Search of human proteins with 223633999

Search of human proteins with 223633999

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]
         (529 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]       1085   0.0  
gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]        911   0.0  
gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]          551   e-157
gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]         317   1e-86
gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]          115   1e-25
gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]          115   1e-25
gi|22748695 DEP domain containing 4 [Homo sapiens]                     62   1e-09
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                46   7e-05
gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]            42   0.001
gi|215820652 StAR-related lipid transfer (START) domain containi...    42   0.001
gi|215820650 StAR-related lipid transfer (START) domain containi...    42   0.001
gi|31543659 StAR-related lipid transfer (START) domain containin...    42   0.001
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         41   0.003
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         41   0.003
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...    40   0.005
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...    40   0.005
gi|54860079 nadrin isoform 1 [Homo sapiens]                            39   0.009
gi|54860105 nadrin isoform 2 [Homo sapiens]                            39   0.009
gi|189571664 DEP domain containing 6 [Homo sapiens]                    39   0.012
gi|40255080 hypothetical protein LOC158763 [Homo sapiens]              39   0.012
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]            39   0.012
gi|156119615 myosin IXA [Homo sapiens]                                 38   0.026
gi|41281907 StAR-related lipid transfer (START) domain containin...    38   0.026
gi|16445031 StAR-related lipid transfer (START) domain containin...    38   0.026
gi|41281898 StAR-related lipid transfer (START) domain containin...    38   0.026
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    37   0.034
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    37   0.034
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    37   0.034
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            37   0.045
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        37   0.045

>gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]
          Length = 529

 Score = 1085 bits (2805), Expect = 0.0
 Identities = 529/529 (100%), Positives = 529/529 (100%)

Query: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60
           MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS
Sbjct: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60

Query: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120
           QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP
Sbjct: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120

Query: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA 180
           NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA
Sbjct: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA 180

Query: 181 NVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELP 240
           NVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELP
Sbjct: 181 NVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELP 240

Query: 241 HWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLG 300
           HWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLG
Sbjct: 241 HWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLG 300

Query: 301 LLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTF 360
           LLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTF
Sbjct: 301 LLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTF 360

Query: 361 SRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGA 420
           SRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGA
Sbjct: 361 SRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGA 420

Query: 421 DMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKS 480
           DMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKS
Sbjct: 421 DMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKS 480

Query: 481 YPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKPFQPFQRTRSFRM 529
           YPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKPFQPFQRTRSFRM
Sbjct: 481 YPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKPFQPFQRTRSFRM 529


>gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]
          Length = 467

 Score =  911 bits (2354), Expect = 0.0
 Identities = 458/529 (86%), Positives = 464/529 (87%), Gaps = 62/529 (11%)

Query: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60
           MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS
Sbjct: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60

Query: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120
           QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP
Sbjct: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120

Query: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA 180
           NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA
Sbjct: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA 180

Query: 181 NVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELP 240
           NVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELP
Sbjct: 181 NVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELP 240

Query: 241 HWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLG 300
           HWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLG
Sbjct: 241 HWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLG 300

Query: 301 LLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTF 360
           LLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTF
Sbjct: 301 LLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTF 360

Query: 361 SRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGA 420
           SRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQ      
Sbjct: 361 SRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQ------ 414

Query: 421 DMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKS 480
                                +Q+SY                            + +Q+ 
Sbjct: 415 ---------------------FQKSYP---------------------------EVYQER 426

Query: 481 YPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKPFQPFQRTRSFRM 529
           +P        TPESAALLFPEKPKPKPQLLMWALKKPFQPFQRTRSFRM
Sbjct: 427 FP--------TPESAALLFPEKPKPKPQLLMWALKKPFQPFQRTRSFRM 467


>gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]
          Length = 527

 Score =  551 bits (1419), Expect = e-157
 Identities = 282/531 (53%), Positives = 379/531 (71%), Gaps = 24/531 (4%)

Query: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60
           ME + V PGPYRAT+LWNE    FRA MPLRKHR  FK Y +CFTA EAVDWL++LLR +
Sbjct: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60

Query: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120
            NFGPEVTR+QT+QLL+KFLKNHVIEDIKG+WG E+ +DN  L+RFP +SPLK  P++ P
Sbjct: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120

Query: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHR------ 174
             +        N++    S++   +  +   S    KRH + + +    ++ H       
Sbjct: 121 ELRK-------NNIE-NFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ 172

Query: 175 ------RQLTEANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQG 228
                 R+L++ +VEE+W+ + L YLQ ILG+ SLEEV++ K V  ++I++N+ + SK+G
Sbjct: 173 ENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRG 232

Query: 229 VVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLT 288
           VVIL +KS +LPHWVLSAMKCLANWP  +D+  P Y+GFE+DVF+TIADY+  L EPLLT
Sbjct: 233 VVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLT 292

Query: 289 FHLFDAFVSVLGLLQK--EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPL 346
           F  ++ FV++LGLLQ   E+VA++A Q+CCLLLPP NRRKLQLLMRM++R+  N +MP L
Sbjct: 293 FEYYELFVNILGLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKL 352

Query: 347 CDGFGTRTLMVQTFSRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEER 406
            D  GTR+LM+ TFSRC+LC  +EVDLDELLA RLV+FLMD++QEIL+VP  LQT++E+ 
Sbjct: 353 HDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKH 412

Query: 407 VAHLRRVQIKYPGADMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLS 466
           + +L++  I+ PG  +   L   S+C+QIS +EF+ Q+   SQ  +A LLE +I +  L 
Sbjct: 413 LDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLP 472

Query: 467 NKEKKKKLKQFQKSYPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKP 517
            KEK+KKLKQFQK YP +YQ+RFPT ES A LF +KP  K  +L+  L+KP
Sbjct: 473 LKEKRKKLKQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLI--LRKP 521


>gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]
          Length = 811

 Score =  317 bits (813), Expect = 1e-86
 Identities = 159/311 (51%), Positives = 216/311 (69%), Gaps = 20/311 (6%)

Query: 1   MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60
           ME + V PGPYRAT+LWNE    FRA MPLRKHR  FK Y +CFTA EAVDWL++LLR +
Sbjct: 1   MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60

Query: 61  QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120
            NFGPEVTR+QT+QLL+KFLKNHVIEDIKG+WG E+ +DN  L+RFP +SPLK  P++ P
Sbjct: 61  SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120

Query: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVH------- 173
             +        N++    S++   +  +   S    KRH + + +    ++ H       
Sbjct: 121 ELRK-------NNI-ENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ 172

Query: 174 -----RRQLTEANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQG 228
                 R+L++ +VEE+W+ + L YLQ ILG+ SLEEV++ K V  ++I++N+ + SK+G
Sbjct: 173 ENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRG 232

Query: 229 VVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLT 288
           VVIL +KS +LPHWVLSAMKCLANWP  +D+  P Y+GFE+DVF+TIADY+  L EPLLT
Sbjct: 233 VVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLT 292

Query: 289 FHLFDAFVSVL 299
           F  ++ FV++L
Sbjct: 293 FEYYELFVNIL 303



 Score =  236 bits (601), Expect = 5e-62
 Identities = 119/213 (55%), Positives = 159/213 (74%), Gaps = 2/213 (0%)

Query: 305 EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSRCI 364
           E+VA++A Q+CCLLLPP NRRKLQLLMRM++R+  N +MP L D  GTR+LM+ TFSRC+
Sbjct: 595 ERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCV 654

Query: 365 LCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGADMDI 424
           LC  +EVDLDELLA RLV+FLMD++QEIL+VP  LQT++E+ + +L++  I+ PG  +  
Sbjct: 655 LCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFA 714

Query: 425 TLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKSYPEV 484
            L   S+C+QIS +EF+ Q+   SQ  +A LLE +I +  L  KEK+KKLKQFQK YP +
Sbjct: 715 PLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLI 774

Query: 485 YQERFPTPESAALLFPEKPKPKPQLLMWALKKP 517
           YQ+RFPT ES A LF +KP  K  +L+  L+KP
Sbjct: 775 YQKRFPTTESEAALFGDKPTIKQPMLI--LRKP 805


>gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]
          Length = 502

 Score =  115 bits (288), Expect = 1e-25
 Identities = 123/507 (24%), Positives = 228/507 (44%), Gaps = 48/507 (9%)

Query: 6   VGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCSQNFGP 65
           V   P+ AT +W+  +   + ++ ++K R R K +  CF  +EAVD +   L  ++ FG 
Sbjct: 19  VAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGD 78

Query: 66  -EVTRKQTVQLLKKFLKNHVIEDIK----GKWGEEDFEDNR-HLYRFPPSSPLKPYPKKP 119
            ++ R + V++ +  +   V E +     GK  +  FED+   LYRF             
Sbjct: 79  VDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTI---------- 128

Query: 120 PNQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTE 179
           PNQ   +   E     P    + +     + ++ +     ++++    +  +     L+ 
Sbjct: 129 PNQDSQLG-KENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSP 187

Query: 180 ANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKF-------IIHNVYSVSKQGVVIL 232
             + E+W+  T+  L +++ L  L+ +L  +    K         + N  +   +G++  
Sbjct: 188 QVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKA 247

Query: 233 DDKSKELPHWVLSAMKCLANWPNC-------SDLKQPMYLGFEKDV-FKTIADYYGHLKE 284
              S+E   W+ +A+ CL   P+        S  +QP      K++ F  I  YY   +E
Sbjct: 248 YSDSQE-DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSS-RE 305

Query: 285 PLLTFHLFDAFVSVLGLLQ--KEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKE 342
           PLL  HL D    +  LL   K ++A+EA Q+   LL  +NR + + L+  MA +  N  
Sbjct: 306 PLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPS 363

Query: 343 MPPLCDGFGTRTLMVQTFSRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTS 402
              L      R ++ + FS+ I+   D  +L +     LV FLMD+ +++ K+P  L   
Sbjct: 364 EFKLQKESDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKI 420

Query: 403 IEERVAHLRRVQIKYPGADMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITD 462
           +  ++  ++    + P  D         +C++I   ++       +++ L  LL+ +  D
Sbjct: 421 VSVKLMAIQNG--RDPNRDAGYI-----YCQRIDQRDYSNNTEKTTKDELLNLLKTLDED 473

Query: 463 AKLSNKEKKKKLKQFQKSYPEVYQERF 489
           +KLS KEKKK L QF K +P+++ E F
Sbjct: 474 SKLSAKEKKKLLGQFYKCHPDIFIEHF 500


>gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]
          Length = 511

 Score =  115 bits (288), Expect = 1e-25
 Identities = 123/507 (24%), Positives = 228/507 (44%), Gaps = 48/507 (9%)

Query: 6   VGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCSQNFGP 65
           V   P+ AT +W+  +   + ++ ++K R R K +  CF  +EAVD +   L  ++ FG 
Sbjct: 28  VAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGD 87

Query: 66  -EVTRKQTVQLLKKFLKNHVIEDIK----GKWGEEDFEDNR-HLYRFPPSSPLKPYPKKP 119
            ++ R + V++ +  +   V E +     GK  +  FED+   LYRF             
Sbjct: 88  VDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTI---------- 137

Query: 120 PNQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTE 179
           PNQ   +   E     P    + +     + ++ +     ++++    +  +     L+ 
Sbjct: 138 PNQDSQLG-KENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSP 196

Query: 180 ANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKF-------IIHNVYSVSKQGVVIL 232
             + E+W+  T+  L +++ L  L+ +L  +    K         + N  +   +G++  
Sbjct: 197 QVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKA 256

Query: 233 DDKSKELPHWVLSAMKCLANWPNC-------SDLKQPMYLGFEKDV-FKTIADYYGHLKE 284
              S+E   W+ +A+ CL   P+        S  +QP      K++ F  I  YY   +E
Sbjct: 257 YSDSQE-DEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSS-RE 314

Query: 285 PLLTFHLFDAFVSVLGLLQ--KEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKE 342
           PLL  HL D    +  LL   K ++A+EA Q+   LL  +NR + + L+  MA +  N  
Sbjct: 315 PLLN-HLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPS 372

Query: 343 MPPLCDGFGTRTLMVQTFSRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTS 402
              L      R ++ + FS+ I+   D  +L +     LV FLMD+ +++ K+P  L   
Sbjct: 373 EFKLQKESDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKI 429

Query: 403 IEERVAHLRRVQIKYPGADMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITD 462
           +  ++  ++    + P  D         +C++I   ++       +++ L  LL+ +  D
Sbjct: 430 VSVKLMAIQNG--RDPNRDAGYI-----YCQRIDQRDYSNNTEKTTKDELLNLLKTLDED 482

Query: 463 AKLSNKEKKKKLKQFQKSYPEVYQERF 489
           +KLS KEKKK L QF K +P+++ E F
Sbjct: 483 SKLSAKEKKKLLGQFYKCHPDIFIEHF 509


>gi|22748695 DEP domain containing 4 [Homo sapiens]
          Length = 294

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 52/208 (25%), Positives = 101/208 (48%), Gaps = 13/208 (6%)

Query: 9   GPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVD-WLHELLRCSQNFGPEV 67
           GP++AT+LW+  +   +A++ +++ R   ++Y+ CFT ++AVD  L  L++ +     ++
Sbjct: 56  GPFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDI 115

Query: 68  TRKQTVQLLKKFLKNHVIEDIK-----GKWGEEDFED-NRHLYRFPPSSPLKPYPKKPPN 121
           +  + V L +  + + V E +       K  E +FED N  LYRF  +       K+   
Sbjct: 116 SCLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKR--- 172

Query: 122 QKDVIKFPEWND-LPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA 180
           QKD     E+N+ L PG    + P+   +    +    H+I         +  ++     
Sbjct: 173 QKDAEN--EFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRL 230

Query: 181 NVEEIWKSMTLSYLQKILGLDSLEEVLD 208
           + E++WK  TL  L +++ L  L+ +L+
Sbjct: 231 SKEDVWKEQTLLCLLQLIHLPFLDNILE 258


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 1/69 (1%)

Query: 275 IADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMM 334
           +  Y   L EPL+TF L+D ++    L ++    ++A Q  C  LPPEN   L+ LM+ +
Sbjct: 348 LKSYLRELPEPLMTFDLYDDWMRAASL-KEPGARLQALQEVCSRLPPENLSNLRYLMKFL 406

Query: 335 ARICLNKEM 343
           AR+   +E+
Sbjct: 407 ARLAEEQEV 415


>gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
          Length = 494

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 34/234 (14%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVA-----------VEAFQICCLL 318
           DV   +  + G L EPLLT   F+A + +  L+Q +              +EA Q+  L+
Sbjct: 175 DVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLI 234

Query: 319 LPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSRCILCSKDEV--DLDEL 376
           LPP NR  L+LL+ ++ +    ++   +     +   +   F+  +L  K+    DL E 
Sbjct: 235 LPPPNRNLLKLLLDLLYQTAKKQDKNKM-----SAYNLALMFAPHVLWPKNVTANDLQEN 289

Query: 377 LAA--RLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGADMDITLSAPSFCRQ 434
           +      + F++ + Q++ K P  ++   E    H    + +    D+D+  S  +   Q
Sbjct: 290 ITKLNSGMAFMIKHSQKLFKAPAYIR---ECARLHYLGSRTQASKDDLDLIASCHTKSFQ 346

Query: 435 ISPEE---------FEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQK 479
           ++  +          + +  + ++E L  L + V  D   S K KK+ ++QF K
Sbjct: 347 LAKSQKRNRVDSCPHQEETQHHTEEALRELFQHV-HDMPESAK-KKQLIRQFNK 398


>gi|215820652 StAR-related lipid transfer (START) domain containing
           8 isoform b [Homo sapiens]
          Length = 1023

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   +  Y+  L EP+ T  L   F+ +  LL K++    A Q   LLLP ENR  LQ 
Sbjct: 639 DVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAA-QAATLLLPDENREVLQT 697

Query: 330 LMRMMARICLNKE 342
           L+  ++ I   +E
Sbjct: 698 LLYFLSDIASAEE 710


>gi|215820650 StAR-related lipid transfer (START) domain containing
           8 isoform a [Homo sapiens]
          Length = 1103

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   +  Y+  L EP+ T  L   F+ +  LL K++    A Q   LLLP ENR  LQ 
Sbjct: 719 DVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAA-QAATLLLPDENREVLQT 777

Query: 330 LMRMMARICLNKE 342
           L+  ++ I   +E
Sbjct: 778 LLYFLSDIASAEE 790


>gi|31543659 StAR-related lipid transfer (START) domain containing 8
           isoform b [Homo sapiens]
          Length = 1023

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   +  Y+  L EP+ T  L   F+ +  LL K++    A Q   LLLP ENR  LQ 
Sbjct: 639 DVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAA-QAATLLLPDENREVLQT 697

Query: 330 LMRMMARICLNKE 342
           L+  ++ I   +E
Sbjct: 698 LLYFLSDIASAEE 710


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 17/126 (13%)

Query: 270  DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
            DV   +  Y+  L EPL+T  L + F+ +   + K++  ++A +   +LLP ENR  LQ 
Sbjct: 1145 DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPDENREVLQT 1203

Query: 330  LMRMMARICL---NKEMPP----LC---DGFGTRTLMVQTFSRCILCSK------DEVDL 373
            L+  ++ +       +M P    +C     F   TL  +  S  ++  K      D+ DL
Sbjct: 1204 LLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDL 1263

Query: 374  DELLAA 379
            +E LAA
Sbjct: 1264 NENLAA 1269


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 17/126 (13%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   +  Y+  L EPL+T  L + F+ +   + K++  ++A +   +LLP ENR  LQ 
Sbjct: 708 DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPDENREVLQT 766

Query: 330 LMRMMARICL---NKEMPP----LC---DGFGTRTLMVQTFSRCILCSK------DEVDL 373
           L+  ++ +       +M P    +C     F   TL  +  S  ++  K      D+ DL
Sbjct: 767 LLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDL 826

Query: 374 DELLAA 379
           +E LAA
Sbjct: 827 NENLAA 832


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 1/80 (1%)

Query: 258 DLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCL 317
           DL++ +YL     V      Y+  L +PLLT+ L+D F   +G+  + +  V+  ++   
Sbjct: 77  DLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEV-LR 135

Query: 318 LLPPENRRKLQLLMRMMARI 337
            LP  N R L+ LMR +  +
Sbjct: 136 ELPVPNYRTLEFLMRHLVHM 155


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 1/80 (1%)

Query: 258 DLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCL 317
           DL++ +YL     V      Y+  L +PLLT+ L+D F   +G+  + +  V+  ++   
Sbjct: 77  DLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEV-LR 135

Query: 318 LLPPENRRKLQLLMRMMARI 337
            LP  N R L+ LMR +  +
Sbjct: 136 ELPVPNYRTLEFLMRHLVHM 155


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)

Query: 245 SAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQK 304
           S +K L    +CS      +      V   +  Y   L EPL+TF+L++ +  V  +  +
Sbjct: 294 SKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQ 353

Query: 305 EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSRCI 364
           +K   + ++  C  LPP+N    + L++ +A++    ++  +     T + +       +
Sbjct: 354 DKKLQDLWR-TCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKM-----TPSNIAIVLGPNL 407

Query: 365 LCSKDEVDLDELLAARLV 382
           L +++E  L E+ AA  V
Sbjct: 408 LWARNEGTLAEMAAATSV 425


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)

Query: 245 SAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQK 304
           S +K L    +CS      +      V   +  Y   L EPL+TF+L++ +  V  +  +
Sbjct: 294 SKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQ 353

Query: 305 EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSRCI 364
           +K   + ++  C  LPP+N    + L++ +A++    ++  +     T + +       +
Sbjct: 354 DKKLQDLWR-TCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKM-----TPSNIAIVLGPNL 407

Query: 365 LCSKDEVDLDELLAARLV 382
           L +++E  L E+ AA  V
Sbjct: 408 LWARNEGTLAEMAAATSV 425


>gi|189571664 DEP domain containing 6 [Homo sapiens]
          Length = 409

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 37/154 (24%), Positives = 64/154 (41%), Gaps = 20/154 (12%)

Query: 30  LRKHRCRFKSYEHCFTAAEAVDWLHELLRCSQNFGPEVTRKQTVQLLKKFLKNHVIEDIK 89
           ++  R   K+Y +CF A E +DWL E    S        R+  ++L++K     +I  + 
Sbjct: 50  IKDRRHHLKTYPNCFVAKELIDWLIEHKEASD-------RETAIKLMQKLADRGIIHHVC 102

Query: 90  GKWGEEDFEDNRHLYR-------FPPSSPLKPYPKKPPNQKDVIKFPEWNDLPPGTSQEN 142
            +   ++F+D +  YR       FP  + +K +  +     + +  PE N L     +E 
Sbjct: 103 DE--HKEFKDVKLFYRFRKDDGTFPLDNEVKAF-MRGQRLYEKLMSPE-NTLLQPREEEG 158

Query: 143 IPVRPVVMNSEM--WYKRHSIAIGEVPACRLVHR 174
           +      M SE   W  +   A     A +L HR
Sbjct: 159 VKYERTFMASEFLDWLVQEGEATTRKEAEQLCHR 192


>gi|40255080 hypothetical protein LOC158763 [Homo sapiens]
          Length = 547

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 42/189 (22%), Positives = 84/189 (44%), Gaps = 31/189 (16%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   + +++  +K+ LL   L+ +F+    L  +++++  A Q+   L+PP +   L+ 
Sbjct: 289 DVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQLS--ALQLLVYLMPPCHSDTLER 346

Query: 330 LMRMMARICLNKEMPPLCDGF------GTRTLMVQTFSRCIL---------CSKDEVDLD 374
           L++ + +I  N E     DG        T T +   F   +L           K ++ +D
Sbjct: 347 LLKALHKITENCEDSIGIDGQLVPGNRMTSTNLALVFGSALLKKGKFGKRESRKTKLGID 406

Query: 375 ELLAA-RLVTFLMDNYQEILKVPLALQTSIEERV-------------AHLRRVQIKYPGA 420
             +A+  +V  ++DN+  + +VP  +Q  + +RV              +LR++Q      
Sbjct: 407 HYVASVNVVRAMIDNWDVLFQVPPHIQRQVAKRVWKSSPEALDFIRRRNLRKIQSARIKM 466

Query: 421 DMDITLSAP 429
           + D  LS P
Sbjct: 467 EEDALLSDP 475


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 8/94 (8%)

Query: 256 CSDLKQPMYLGF-------EKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVA 308
           C +L+   Y G        + D    +  +   L +PLL+     AF +V  L  K K  
Sbjct: 377 CQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTK-KQQ 435

Query: 309 VEAFQICCLLLPPENRRKLQLLMRMMARICLNKE 342
           ++A  +  +LLP  NR  L+ L+  + R+  NKE
Sbjct: 436 LQALNLLVILLPDANRDTLKALLEFLQRVIDNKE 469


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 51/237 (21%), Positives = 91/237 (38%), Gaps = 28/237 (11%)

Query: 282  LKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNK 341
            L  PL+TF L++ F+  +G LQ+ K  +         L   +   L+ L+  + RI L +
Sbjct: 2141 LPNPLMTFELYEEFLRAMG-LQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQE 2199

Query: 342  EMPPLCDGFGTRTLMVQTFSRCILCSKD---------EVDLDELLAARLVTFLMDNYQEI 392
            +   +     +   +   F+ CIL   D         ++         +V   M+ Y+  
Sbjct: 2200 DTNRM-----SANALAIVFAPCILRCPDTTDPLQSVQDISKTTTCVELIVVEQMNKYKAR 2254

Query: 393  LKVPLAL---QTSIEERVAHLRRVQIK-------YPGADMDITLSAPS---FCRQISPEE 439
            LK   +L   +   + R++ +RR   K       YPG    + +  PS      +    E
Sbjct: 2255 LKDISSLEFAENKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSE 2314

Query: 440  FEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKSYPEVYQERFPTPESAA 496
               +     Q+  A   EE +   ++ N +K+K+   F+    E       T ES A
Sbjct: 2315 AAMETDITEQQQAAMQQEERVLTEQIENLQKEKEELTFEMLVLEPRASDDETLESEA 2371


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   +  ++  L EPL T  L + F+ +   + KE+  ++A Q   LLL  ENR  LQ 
Sbjct: 722 DVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLADENREVLQT 780

Query: 330 LM 331
           L+
Sbjct: 781 LL 782


>gi|16445031 StAR-related lipid transfer (START) domain containing
           13 isoform gamma [Homo sapiens]
          Length = 995

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   +  ++  L EPL T  L + F+ +   + KE+  ++A Q   LLL  ENR  LQ 
Sbjct: 612 DVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLADENREVLQT 670

Query: 330 LM 331
           L+
Sbjct: 671 LL 672


>gi|41281898 StAR-related lipid transfer (START) domain containing
           13 isoform alpha [Homo sapiens]
          Length = 1113

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   +  ++  L EPL T  L + F+ +   + KE+  ++A Q   LLL  ENR  LQ 
Sbjct: 730 DVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLADENREVLQT 788

Query: 330 LM 331
           L+
Sbjct: 789 LL 790


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 19/151 (12%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   + ++   + +PLLT  L+ AF++ L L  +E++     Q+   LLPP N   L  
Sbjct: 261 DVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLG--TLQLLIYLLPPCNCDTLHR 318

Query: 330 LMRMMARICLNKEMPPLCDG----------------FGTRTLMVQTFSRCILCSKDEVDL 373
           L++ ++ +  + +     DG                FG   L  Q  S      +     
Sbjct: 319 LLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARA 378

Query: 374 DELLA-ARLVTFLMDNYQEILKVPLALQTSI 403
           +E  A   +V  +++NY+ +  VP  LQ  +
Sbjct: 379 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 409


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 19/151 (12%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   + ++   + +PLLT  L+ AF++ L L  +E++     Q+   LLPP N   L  
Sbjct: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLG--TLQLLIYLLPPCNCDTLHR 521

Query: 330 LMRMMARICLNKEMPPLCDG----------------FGTRTLMVQTFSRCILCSKDEVDL 373
           L++ ++ +  + +     DG                FG   L  Q  S      +     
Sbjct: 522 LLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARA 581

Query: 374 DELLA-ARLVTFLMDNYQEILKVPLALQTSI 403
           +E  A   +V  +++NY+ +  VP  LQ  +
Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 19/151 (12%)

Query: 270 DVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQL 329
           DV   + ++   + +PLLT  L+ AF++ L L  +E++     Q+   LLPP N   L  
Sbjct: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLG--TLQLLIYLLPPCNCDTLHR 521

Query: 330 LMRMMARICLNKEMPPLCDG----------------FGTRTLMVQTFSRCILCSKDEVDL 373
           L++ ++ +  + +     DG                FG   L  Q  S      +     
Sbjct: 522 LLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARA 581

Query: 374 DELLA-ARLVTFLMDNYQEILKVPLALQTSI 403
           +E  A   +V  +++NY+ +  VP  LQ  +
Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 1/82 (1%)

Query: 256 CSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQIC 315
           C DL + +YL     V      Y+  L  PLLT+ L++ F   +    +E   +   Q  
Sbjct: 76  CPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEG-QLARIQNV 134

Query: 316 CLLLPPENRRKLQLLMRMMARI 337
              LPP + R L+ L+R +A I
Sbjct: 135 IQELPPSHYRTLEYLIRHLAHI 156


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 16/63 (25%), Positives = 35/63 (55%), Gaps = 1/63 (1%)

Query: 275 IADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMM 334
           +  Y   L EPL+TF L+D ++    + +++K  ++A    C  LP  N   ++ L++ +
Sbjct: 327 LKSYLRELPEPLMTFELYDEWIQASNVQEQDK-KLQALWNACEKLPKANHNNIRYLIKFL 385

Query: 335 ARI 337
           +++
Sbjct: 386 SKL 388


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,379,388
Number of Sequences: 37866
Number of extensions: 1061770
Number of successful extensions: 3494
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 3424
Number of HSP's gapped (non-prelim): 108
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.