Guide to the Human Genome
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Search of human proteins with 223029444

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223029444 mothers against decapentaplegic homolog 3 isoform
4 [Homo sapiens]
         (230 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [...   487   e-138
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4...   487   e-138
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3...   487   e-138
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2...   487   e-138
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]   449   e-127
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]    449   e-127
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi...   449   e-127
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]        345   2e-95
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]        345   2e-95
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]        345   2e-95
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]             343   5e-95
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]              343   5e-95
gi|5174519 SMAD family member 9 isoform b [Homo sapiens]              339   1e-93
gi|187828357 SMAD family member 9 isoform a [Homo sapiens]            335   1e-92
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]   171   4e-43
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]            100   2e-21
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]             100   2e-21
gi|5174517 SMAD family member 7 [Homo sapiens]                         89   4e-18
gi|34452173 integrin alpha X precursor [Homo sapiens]                  31   0.78 
gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]            28   5.0  
gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo s...    28   8.6  
gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo s...    28   8.6  
gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo s...    28   8.6  

>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
           [Homo sapiens]
          Length = 425

 Score =  487 bits (1253), Expect = e-138
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60
           MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
Sbjct: 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255

Query: 61  TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120
           TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV
Sbjct: 256 TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315

Query: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180
           QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS
Sbjct: 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375

Query: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
Sbjct: 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425


>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
           [Homo sapiens]
          Length = 230

 Score =  487 bits (1253), Expect = e-138
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60
           MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
Sbjct: 1   MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60

Query: 61  TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120
           TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV
Sbjct: 61  TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120

Query: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180
           QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS
Sbjct: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180

Query: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
Sbjct: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230


>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
           [Homo sapiens]
          Length = 381

 Score =  487 bits (1253), Expect = e-138
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60
           MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
Sbjct: 152 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 211

Query: 61  TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120
           TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV
Sbjct: 212 TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 271

Query: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180
           QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS
Sbjct: 272 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 331

Query: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
Sbjct: 332 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381


>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
           [Homo sapiens]
          Length = 320

 Score =  487 bits (1253), Expect = e-138
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60
           MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
Sbjct: 91  MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 150

Query: 61  TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120
           TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV
Sbjct: 151 TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 210

Query: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180
           QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS
Sbjct: 211 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 270

Query: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
Sbjct: 271 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 320


>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  449 bits (1156), Expect = e-127
 Identities = 212/231 (91%), Positives = 222/231 (96%), Gaps = 1/231 (0%)

Query: 1   MNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPS 59
           +N SMD GSP  LSP  +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS
Sbjct: 237 LNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPS 296

Query: 60  MTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 119
           +TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIF
Sbjct: 297 LTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIF 356

Query: 120 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 179
           VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM
Sbjct: 357 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 416

Query: 180 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 417 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  449 bits (1156), Expect = e-127
 Identities = 212/231 (91%), Positives = 222/231 (96%), Gaps = 1/231 (0%)

Query: 1   MNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPS 59
           +N SMD GSP  LSP  +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS
Sbjct: 237 LNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPS 296

Query: 60  MTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 119
           +TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIF
Sbjct: 297 LTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIF 356

Query: 120 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 179
           VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM
Sbjct: 357 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 416

Query: 180 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 417 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
           sapiens]
          Length = 437

 Score =  449 bits (1156), Expect = e-127
 Identities = 212/231 (91%), Positives = 222/231 (96%), Gaps = 1/231 (0%)

Query: 1   MNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPS 59
           +N SMD GSP  LSP  +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS
Sbjct: 207 LNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPS 266

Query: 60  MTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 119
           +TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIF
Sbjct: 267 LTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIF 326

Query: 120 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 179
           VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM
Sbjct: 327 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 386

Query: 180 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 387 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  345 bits (885), Expect = 2e-95
 Identities = 167/223 (74%), Positives = 188/223 (84%), Gaps = 2/223 (0%)

Query: 9   SPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDP 68
           S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RVGE FHAS  S+ VDGFTDP
Sbjct: 244 SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDP 302

Query: 69  SNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ 127
           SN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN 
Sbjct: 303 SNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNF 362

Query: 128 RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGA 187
            +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFVKGWGA
Sbjct: 363 HHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGA 422

Query: 188 EYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           EY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 423 EYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  345 bits (885), Expect = 2e-95
 Identities = 167/223 (74%), Positives = 188/223 (84%), Gaps = 2/223 (0%)

Query: 9   SPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDP 68
           S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RVGE FHAS  S+ VDGFTDP
Sbjct: 244 SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDP 302

Query: 69  SNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ 127
           SN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN 
Sbjct: 303 SNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNF 362

Query: 128 RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGA 187
            +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFVKGWGA
Sbjct: 363 HHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGA 422

Query: 188 EYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           EY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 423 EYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  345 bits (885), Expect = 2e-95
 Identities = 167/223 (74%), Positives = 188/223 (84%), Gaps = 2/223 (0%)

Query: 9   SPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDP 68
           S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RVGE FHAS  S+ VDGFTDP
Sbjct: 244 SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDP 302

Query: 69  SNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ 127
           SN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN 
Sbjct: 303 SNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNF 362

Query: 128 RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGA 187
            +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFVKGWGA
Sbjct: 363 HHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGA 422

Query: 188 EYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           EY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 423 EYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  343 bits (881), Expect = 5e-95
 Identities = 164/221 (74%), Positives = 183/221 (82%), Gaps = 1/221 (0%)

Query: 11  NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN 70
           N+   P+    N  D+Q V Y EP  WCSI YYELN RVGE FHAS  S+ VDGFTDPSN
Sbjct: 245 NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSN 304

Query: 71  SE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 129
           ++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN  +
Sbjct: 305 NKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHH 364

Query: 130 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 189
           G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY
Sbjct: 365 GFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEY 424

Query: 190 RRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
            RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 425 HRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  343 bits (881), Expect = 5e-95
 Identities = 164/221 (74%), Positives = 183/221 (82%), Gaps = 1/221 (0%)

Query: 11  NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN 70
           N+   P+    N  D+Q V Y EP  WCSI YYELN RVGE FHAS  S+ VDGFTDPSN
Sbjct: 245 NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSN 304

Query: 71  SE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 129
           ++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN  +
Sbjct: 305 NKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHH 364

Query: 130 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 189
           G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY
Sbjct: 365 GFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEY 424

Query: 190 RRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
            RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 425 HRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
          Length = 430

 Score =  339 bits (870), Expect = 1e-93
 Identities = 161/223 (72%), Positives = 186/223 (83%), Gaps = 2/223 (0%)

Query: 9   SPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDP 68
           SP     P SP + + D +PV Y EP  WCS++YYELN RVGETF AS  S+ +DGFTDP
Sbjct: 209 SPGSPSEPESP-YQHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDP 267

Query: 69  SNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ 127
           SN+  RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN 
Sbjct: 268 SNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNY 327

Query: 128 RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGA 187
           ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGA
Sbjct: 328 QHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGA 387

Query: 188 EYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           EY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 388 EYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430


>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
          Length = 467

 Score =  335 bits (860), Expect = 1e-92
 Identities = 157/209 (75%), Positives = 180/209 (86%), Gaps = 1/209 (0%)

Query: 23  NLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSN 81
           N D +PV Y EP  WCS++YYELN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLSN
Sbjct: 259 NGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSN 318

Query: 82  VNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP 141
           VNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP 
Sbjct: 319 VNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPS 378

Query: 142 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 201
           GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWI
Sbjct: 379 GCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWI 438

Query: 202 ELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
           E+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 439 EIHLHGPLQWLDKVLTQMGSPHNPISSVS 467


>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
          Length = 552

 Score =  171 bits (434), Expect = 4e-43
 Identities = 105/252 (41%), Positives = 139/252 (55%), Gaps = 42/252 (16%)

Query: 10  PNLSPNPMS--PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVD 63
           P + P+P    P HN L  QP     PA  +WCSI+Y+E++ +VGETF   +S P +TVD
Sbjct: 292 PPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVD 351

Query: 64  GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQS 122
           G+ DPS  +RFCLG LSNV+R  A+E  R HIG+GV+L   G G+V+  CLSD A+FVQS
Sbjct: 352 GYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQS 411

Query: 123 PNCNQRYGWHPA-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------- 166
              ++  G  P   V KI P   +K+F+         Q+ A   A +  Q          
Sbjct: 412 YYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPG 471

Query: 167 -------------------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 207
                               V  L R+C +RMSFVKGWG +Y RQ++  TPCWIE+HL+ 
Sbjct: 472 PGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHR 531

Query: 208 PLQWLDKVLTQM 219
            LQ LD+VL  M
Sbjct: 532 ALQLLDEVLHTM 543


>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
          Length = 235

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 60/176 (34%), Positives = 91/176 (51%), Gaps = 7/176 (3%)

Query: 33  EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR 92
           +P+ WCS++Y+E   RVG  +     ++++  F D      FCLG L+   R+ +V  TR
Sbjct: 66  KPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTR 123

Query: 93  RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 152
             IG G+ L      V+A    +  IFV SP  +   G     V K+PPG ++K+F+ + 
Sbjct: 124 SKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFER 182

Query: 153 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 208
                A   +   +  Y      ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 183 SGLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 234


>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 60/176 (34%), Positives = 91/176 (51%), Gaps = 7/176 (3%)

Query: 33  EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR 92
           +P+ WCS++Y+E   RVG  +     ++++  F D      FCLG L+   R+ +V  TR
Sbjct: 327 KPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTR 384

Query: 93  RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 152
             IG G+ L      V+A    +  IFV SP  +   G     V K+PPG ++K+F+ + 
Sbjct: 385 SKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFER 443

Query: 153 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 208
                A   +   +  Y      ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 444 SGLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495


>gi|5174517 SMAD family member 7 [Homo sapiens]
          Length = 426

 Score = 88.6 bits (218), Expect = 4e-18
 Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 12/204 (5%)

Query: 4   SMDAGSPN-LSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTV 62
           S + G  N L+P  +S +   L L+P    + + WC ++Y+E   RVG  +   +PS+ +
Sbjct: 232 SAETGGTNYLAPGGLSDSQ--LLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSLDI 286

Query: 63  DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 122
             F D      FCLG L++ N++  V+  R  IG G++L      V+    S   IF++S
Sbjct: 287 --FYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKS 344

Query: 123 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 182
              +         V K+ PG ++K F+ ++  +L  Q  N   E + Q     T+++SFV
Sbjct: 345 ATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFV 400

Query: 183 KGWGAEYRRQTVTSTPCWIELHLN 206
           KGWG  Y RQ ++S PCW+E+  N
Sbjct: 401 KGWGQCYTRQFISSCPCWLEVIFN 424


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score = 31.2 bits (69), Expect = 0.78
 Identities = 13/39 (33%), Positives = 21/39 (53%)

Query: 190  RRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSS 228
            +R    S   W+ + LN    W+D  ++   +PS+RCSS
Sbjct: 962  QRDLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSS 1000


>gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]
          Length = 306

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 11/74 (14%)

Query: 9  SPNLSPNPMSPAHNNLDL-----QPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 63
          SP L  N M+ AH+N  L      P +  + A    + +YE +    E  HASQ  +   
Sbjct: 13 SPRLEHNGMTSAHHNFRLPGSRDSPASASQVAEIIDLEWYEKS----EETHASQIELLET 68

Query: 64 GFT-DPSN-SERFC 75
            T +P N SE FC
Sbjct: 69 SSTQEPLNASEAFC 82


>gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo
           sapiens]
          Length = 1020

 Score = 27.7 bits (60), Expect = 8.6
 Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 103 YIGGEVFAECLSDSAIFVQSPNCNQRYGW-HPATVCKIPPGCNLKIFNNQEFAALLAQSV 161
           Y  G+  +E L D         C+ R    HPA     P G  ++ +++ E   ++  S+
Sbjct: 920 YAWGKTISELLQD---------CSSRLKMTHPARALYTPSGEPIQSWDDIERDMVICVSM 970

Query: 162 NQGFEAVYQLTRMCTIRMSFVK 183
             GF+   +L ++  IR ++ +
Sbjct: 971 GHGFKTPKELKQLMEIRANYAR 992


>gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo
           sapiens]
          Length = 1020

 Score = 27.7 bits (60), Expect = 8.6
 Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 103 YIGGEVFAECLSDSAIFVQSPNCNQRYGW-HPATVCKIPPGCNLKIFNNQEFAALLAQSV 161
           Y  G+  +E L D         C+ R    HPA     P G  ++ +++ E   ++  S+
Sbjct: 920 YAWGKTISELLQD---------CSSRLKMTHPARALYTPSGEPIQSWDDIERDMVICVSM 970

Query: 162 NQGFEAVYQLTRMCTIRMSFVK 183
             GF+   +L ++  IR ++ +
Sbjct: 971 GHGFKTPKELKQLMEIRANYAR 992


>gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo
           sapiens]
          Length = 1020

 Score = 27.7 bits (60), Expect = 8.6
 Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 103 YIGGEVFAECLSDSAIFVQSPNCNQRYGW-HPATVCKIPPGCNLKIFNNQEFAALLAQSV 161
           Y  G+  +E L D         C+ R    HPA     P G  ++ +++ E   ++  S+
Sbjct: 920 YAWGKTISELLQD---------CSSRLKMTHPARALYTPSGEPIQSWDDIERDMVICVSM 970

Query: 162 NQGFEAVYQLTRMCTIRMSFVK 183
             GF+   +L ++  IR ++ +
Sbjct: 971 GHGFKTPKELKQLMEIRANYAR 992


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,631,507
Number of Sequences: 37866
Number of extensions: 420570
Number of successful extensions: 781
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 745
Number of HSP's gapped (non-prelim): 24
length of query: 230
length of database: 18,247,518
effective HSP length: 99
effective length of query: 131
effective length of database: 14,498,784
effective search space: 1899340704
effective search space used: 1899340704
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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