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Search of human proteins with 223029420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223029420 SKI-like isoform 2 [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223029420 SKI-like isoform 2 [Homo sapiens] 1279 0.0
gi|223029418 SKI-like isoform 1 [Homo sapiens] 1255 0.0
gi|223029422 SKI-like isoform 3 [Homo sapiens] 1217 0.0
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens] 367 e-101
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 121 2e-27
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 121 2e-27
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 121 2e-27
gi|73476377 LBXCOR1 homolog [Homo sapiens] 109 9e-24
gi|156104908 myosin heavy chain 6 [Homo sapiens] 57 4e-08
gi|21735548 centrosomal protein 2 [Homo sapiens] 55 2e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 55 3e-07
gi|148746195 trichohyalin [Homo sapiens] 54 3e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 54 4e-07
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 54 6e-07
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 53 8e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 1e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 53 1e-06
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 52 1e-06
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 52 1e-06
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 52 1e-06
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 52 1e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 2e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 52 2e-06
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 52 2e-06
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 52 2e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 52 2e-06
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 52 2e-06
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 52 2e-06
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 52 2e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 51 3e-06
>gi|223029420 SKI-like isoform 2 [Homo sapiens]
Length = 638
Score = 1279 bits (3310), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA 60
MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA
Sbjct: 1 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA 60
Query: 61 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV 120
PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
Sbjct: 61 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV 120
Query: 121 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL 180
FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
Sbjct: 121 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL 180
Query: 181 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP 240
QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
Sbjct: 181 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP 240
Query: 241 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP 300
QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
Sbjct: 241 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP 300
Query: 301 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG 360
QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
Sbjct: 301 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG 360
Query: 361 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS 420
KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
Sbjct: 361 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS 420
Query: 421 QSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDD 480
QSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDD
Sbjct: 421 QSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDD 480
Query: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQ 540
KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQ
Sbjct: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQ 540
Query: 541 NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD 600
NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD
Sbjct: 541 NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD 600
Query: 601 RQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
RQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE
Sbjct: 601 RQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
>gi|223029418 SKI-like isoform 1 [Homo sapiens]
Length = 684
Score = 1255 bits (3248), Expect = 0.0
Identities = 637/684 (93%), Positives = 638/684 (93%), Gaps = 46/684 (6%)
Query: 1 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA 60
MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA
Sbjct: 1 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA 60
Query: 61 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV 120
PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
Sbjct: 61 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV 120
Query: 121 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL 180
FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
Sbjct: 121 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL 180
Query: 181 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP 240
QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
Sbjct: 181 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP 240
Query: 241 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP 300
QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
Sbjct: 241 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP 300
Query: 301 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG 360
QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
Sbjct: 301 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG 360
Query: 361 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS 420
KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
Sbjct: 361 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS 420
Query: 421 QSKELTKTEA----------------------------------------------NASI 434
QSKELTKTEA +ASI
Sbjct: 421 QSKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASI 480
Query: 435 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK 494
SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK
Sbjct: 481 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK 540
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 554
QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ
Sbjct: 541 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 600
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA 614
KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA
Sbjct: 601 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA 660
Query: 615 RQKLEMMIKELKLQILKSSKTAKE 638
RQKLEMMIKELKLQILKSSKTAKE
Sbjct: 661 RQKLEMMIKELKLQILKSSKTAKE 684
>gi|223029422 SKI-like isoform 3 [Homo sapiens]
Length = 664
Score = 1217 bits (3148), Expect = 0.0
Identities = 617/664 (92%), Positives = 618/664 (93%), Gaps = 46/664 (6%)
Query: 21 MGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEAPVETDGEHVKRTCTSVPETL 80
MGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEAPVETDGEHVKRTCTSVPETL
Sbjct: 1 MGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEAPVETDGEHVKRTCTSVPETL 60
Query: 81 HLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTVFLPLPSPQVLPGPLLIPSDS 140
HLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTVFLPLPSPQVLPGPLLIPSDS
Sbjct: 61 HLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTVFLPLPSPQVLPGPLLIPSDS 120
Query: 141 STELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSD 200
STELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSD
Sbjct: 121 STELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSD 180
Query: 201 QLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGS 260
QLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGS
Sbjct: 181 QLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGS 240
Query: 261 AFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDKRTCHWGF 320
AFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDKRTCHWGF
Sbjct: 241 AFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDKRTCHWGF 300
Query: 321 ESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSKTDAPSGMELQSWYP 380
ESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSKTDAPSGMELQSWYP
Sbjct: 301 ESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSKTDAPSGMELQSWYP 360
Query: 381 VIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQSKELTKTEA---------- 430
VIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQSKELTKTEA
Sbjct: 361 VIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQSKELTKTEASKSISRQSEK 420
Query: 431 ------------------------------------NASISNNSTSKRKSESATCNLVRD 454
+ASISNNSTSKRKSESATCNLVRD
Sbjct: 421 AHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASISNNSTSKRKSESATCNLVRD 480
Query: 455 INKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVK 514
INKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVK
Sbjct: 481 INKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVK 540
Query: 515 MLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSN 574
MLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSN
Sbjct: 541 MLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSN 600
Query: 575 LEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK 634
LEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK
Sbjct: 601 LEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK 660
Query: 635 TAKE 638
TAKE
Sbjct: 661 TAKE 664
>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
Length = 728
Score = 367 bits (941), Expect = e-101
Identities = 244/697 (35%), Positives = 350/697 (50%), Gaps = 151/697 (21%)
Query: 83 NPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMS-----------------------PT 119
+P L+ TL QFHLSS SSLGGPAAFSAR +QE+ P
Sbjct: 14 HPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEAYKKESAKEAGAAAVPAPVPAATEPPPV 73
Query: 120 VFLPL--PSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLRE 177
+ LP P P VLPGP +PSD STE +TVLEGE+ISCF VGGEKRLCLPQ+LNSVLR+
Sbjct: 74 LHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRD 133
Query: 178 FTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPR 237
F+LQQIN VCDEL+IYCSRCT+DQL ILKV+GILPF+APSCGLIT TDA+RLCNALL
Sbjct: 134 FSLQQINAVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGG 193
Query: 238 TFPQNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGM 297
+P A S L+ + + V HEC GKC+GL P+ Y P A CIQCL+C M
Sbjct: 194 AYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLM 253
Query: 298 FAPQTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSM 357
+ P FV+HSH++ + RTCHWGF+SA W Y+ ++Q Y G E+ +L L+++KEKF
Sbjct: 254 YPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDY 313
Query: 358 RSGKRNQ--------------------SKTDAPSGMELQS-------------------- 377
+ + + S++ APS + S
Sbjct: 314 GNKYKRRVPRVSSEPPASIRPKTDDTSSQSPAPSEKDKPSSWLRTLAGSSNKSLGCVHPR 373
Query: 378 --------WYPVIKQEGDHVS-QTHSFLHPSYYLYMC-DKVVAPNVSL------------ 415
W P + +S + + S+Y Y + VAPNV+L
Sbjct: 374 QRLSAFRPWSPAVSASEKELSPHLPALIRDSFYSYKSFETAVAPNVALAPPAQQKVVSSP 433
Query: 416 --TSAVSQSKELTKT--------------------------------EANASI-SNNSTS 440
+AVS++ E T EA + S +
Sbjct: 434 PCAAAVSRAPEPLATCTQPRKRKLTVDTPGAPETLAPVAAPEEDKDSEAEVEVESREEFT 493
Query: 441 KRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQ--QEK 498
S ++ + + +G A + P V D D +E + +L+Q +
Sbjct: 494 SSLSSLSSPSFTSSSSAKDLGSPGARALPSAVPDAAAPADAPSGLEAELE-HLRQALEGG 552
Query: 499 LNLILQKKQQLQMEVKM-LSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDL 557
L+ K++ L VKM + + + + +++L +ELE L+ +++ E +++L
Sbjct: 553 LDTKEAKEKFLHEVVKMRVKQEEKLSAALQAKRSLHQELEFLRVAKKEKLREATEAKRNL 612
Query: 558 EKKLEQI------------------------MKQKCTCDSNLEKDK-EAEYAGQLAELRQ 592
K++E++ +Q CD E + A+Y+ Q+ +L+
Sbjct: 613 RKEIERLRAENEKKMKEANESRLRLKRELEQARQARVCDKGCEAGRLRAKYSAQIEDLQV 672
Query: 593 RLDHAEADRQELQDELRQEREARQKLEMMIKELKLQI 629
+L HAEADR++L+ +L +EREAR+ LE ++KEL+ Q+
Sbjct: 673 KLQHAEADREQLRADLLREREAREHLEKVVKELQEQL 709
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 121 bits (304), Expect = 2e-27
Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 30/252 (11%)
Query: 120 VFLPLPSPQVLPGPLLIPSDSSTELT-----QTVLEGESISCFQVGGEKRLCLPQVLNSV 174
+ L PS P L P L Q +L G I + G++RLCL Q+ N++
Sbjct: 12 ILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTL 71
Query: 175 LREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALL 234
L+ F+ +I+ L I C +CT QL IL+ G +P ++ CG+IT +A+RLC + L
Sbjct: 72 LKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFL 131
Query: 235 ---RPRTFPQNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQC 291
RP P N AF+V HEC C+G F P Y A CI+C
Sbjct: 132 GENRPPKLPDN-----------------FAFDVSHECAWGCRGSFIPARYNSSRAKCIKC 174
Query: 292 LECCGMFAPQTFVMHSHRSPD-KRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEE 350
C F+P F+ HSHR+PD K T W +L + K +P++ +L E+
Sbjct: 175 SYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDK---SPQD-ELVFAWED 230
Query: 351 MKEKFSMRSGKR 362
+K F+ S KR
Sbjct: 231 VKAMFNGGSRKR 242
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 121 bits (304), Expect = 2e-27
Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 30/252 (11%)
Query: 120 VFLPLPSPQVLPGPLLIPSDSSTELT-----QTVLEGESISCFQVGGEKRLCLPQVLNSV 174
+ L PS P L P L Q +L G I + G++RLCL Q+ N++
Sbjct: 12 ILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTL 71
Query: 175 LREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALL 234
L+ F+ +I+ L I C +CT QL IL+ G +P ++ CG+IT +A+RLC + L
Sbjct: 72 LKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFL 131
Query: 235 ---RPRTFPQNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQC 291
RP P N AF+V HEC C+G F P Y A CI+C
Sbjct: 132 GENRPPKLPDN-----------------FAFDVSHECAWGCRGSFIPARYNSSRAKCIKC 174
Query: 292 LECCGMFAPQTFVMHSHRSPD-KRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEE 350
C F+P F+ HSHR+PD K T W +L + K +P++ +L E+
Sbjct: 175 SYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDK---SPQD-ELVFAWED 230
Query: 351 MKEKFSMRSGKR 362
+K F+ S KR
Sbjct: 231 VKAMFNGGSRKR 242
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 121 bits (304), Expect = 2e-27
Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 30/252 (11%)
Query: 120 VFLPLPSPQVLPGPLLIPSDSSTELT-----QTVLEGESISCFQVGGEKRLCLPQVLNSV 174
+ L PS P L P L Q +L G I + G++RLCL Q+ N++
Sbjct: 12 ILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTL 71
Query: 175 LREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALL 234
L+ F+ +I+ L I C +CT QL IL+ G +P ++ CG+IT +A+RLC + L
Sbjct: 72 LKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFL 131
Query: 235 ---RPRTFPQNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQC 291
RP P N AF+V HEC C+G F P Y A CI+C
Sbjct: 132 GENRPPKLPDN-----------------FAFDVSHECAWGCRGSFIPARYNSSRAKCIKC 174
Query: 292 LECCGMFAPQTFVMHSHRSPD-KRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEE 350
C F+P F+ HSHR+PD K T W +L + K +P++ +L E+
Sbjct: 175 SYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDK---SPQD-ELVFAWED 230
Query: 351 MKEKFSMRSGKR 362
+K F+ S KR
Sbjct: 231 VKAMFNGGSRKR 242
>gi|73476377 LBXCOR1 homolog [Homo sapiens]
Length = 921
Score = 109 bits (272), Expect = 9e-24
Identities = 60/175 (34%), Positives = 92/175 (52%), Gaps = 20/175 (11%)
Query: 143 ELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQL 202
++ +T L G I + G++RLCL Q+ N++L+ ++ +I+ L I C +CT QL
Sbjct: 67 QVGETSLYGVPIVSLVIDGQERLCLAQISNTLLKNYSYNEIHNRRVALGITCVQCTPVQL 126
Query: 203 HILKVLGILPFNAPSCGLITLTDAQRLCNALL---RPRTFPQNGSVLPAKSSLAQLKETG 259
IL+ G +P ++ CG+IT +A+RLC + L +P P+N
Sbjct: 127 EILRRAGAMPISSRRCGMITKREAERLCKSFLGEHKPPKLPEN----------------- 169
Query: 260 SAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDKR 314
AF+V HEC +G F P Y A CI+C C F+P F+ HSHR+PD +
Sbjct: 170 FAFDVVHECAWGSRGSFIPARYNSSRAKCIKCGYCSMYFSPNKFIFHSHRTPDAK 224
Score = 40.0 bits (92), Expect = 0.007
Identities = 26/93 (27%), Positives = 51/93 (54%), Gaps = 10/93 (10%)
Query: 532 LQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELR 591
++K++E+L E Q++ +EQ +L KKLE+ + +L+ + + + +LA
Sbjct: 809 VEKDIENLAREELQKL---LLEQMELRKKLEREFQ-------SLKDNFQDQMKRELAYRE 858
Query: 592 QRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
+ + + R L +EL QER+AR ++ +KE
Sbjct: 859 EMVQQLQIVRDTLCNELDQERKARYAIQQKLKE 891
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 57.4 bits (137), Expect = 4e-08
Identities = 59/252 (23%), Positives = 122/252 (48%), Gaps = 22/252 (8%)
Query: 405 CDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVA 464
CD+++ + L + V + E + E + + + KRK E L +DI+ + + L
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMN-AELTAKKRKLEDECSELKKDIDDLELTLAK 965
Query: 465 AASSPLLVKDVI---CEDDKGKIMEEVMRTYLKQQEKLNLILQKK-QQLQMEV-KMLSSS 519
++ + E+ G ++E++ K+++ L Q+ LQ+E K+ S S
Sbjct: 966 VEKEKHATENKVKNLTEEMAG--LDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLS 1023
Query: 520 KSMKELTEEQQNLQKELES-----LQNEHAQRM--------EEFYVEQKDLEKKLEQIMK 566
KS +L ++ +L+ LE + E A+R +E ++ ++ + +LE+ +K
Sbjct: 1024 KSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLK 1083
Query: 567 QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELK 626
+K D N + K + +L+++L +A +EL++EL ER AR K+E + +L
Sbjct: 1084 KK-EFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLS 1142
Query: 627 LQILKSSKTAKE 638
++ + S+ +E
Sbjct: 1143 RELEEISERLEE 1154
Score = 50.4 bits (119), Expect = 5e-06
Identities = 70/295 (23%), Positives = 127/295 (43%), Gaps = 42/295 (14%)
Query: 340 EEKKLKIILEEMKEKFSMRSGKRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPS 399
+EKK+++ LE K K +S D + +LQ + K+E D ++Q +S +
Sbjct: 1042 QEKKVRMDLERAKRKLEGDLKLTQESIMDLEND-KLQLEEKLKKKEFD-INQQNSKIEDE 1099
Query: 400 YYLYMCDKVVAPNVSLTSAVSQSKELTKTEANAS-----ISNNSTSKRKSESATCNLVRD 454
L A+ K+L + +A + T++ K E +L R+
Sbjct: 1100 QVL---------------ALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRE 1144
Query: 455 INKVGIGLVAA--ASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQME 512
+ ++ L A A+S + + E + K+ ++ L Q E L+KK
Sbjct: 1145 LEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL-QHEATAAALRKKH----- 1198
Query: 513 VKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCD 572
+ S+ EL E+ NLQ+ + L+ E + EF +E D+ +EQI+K K +
Sbjct: 1199 ------ADSVAELGEQIDNLQRVKQKLEKEKS----EFKLELDDVTSNMEQIIKAKANLE 1248
Query: 573 --SNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKEL 625
S +D+ EY +L E ++ L+ R +LQ E + ++ E +I +L
Sbjct: 1249 KVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
Score = 39.7 bits (91), Expect = 0.009
Identities = 40/192 (20%), Positives = 86/192 (44%), Gaps = 36/192 (18%)
Query: 478 EDDKGKIMEEVMRTYLKQ---QEKLNLILQKKQQLQMEV--------------------- 513
+++ G+I E + ++ ++ +EK+ +LQ+K LQ++V
Sbjct: 855 KEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNK 914
Query: 514 -KMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCD 572
++ + K M E E+++ + EL + + + E + DLE L ++ K+K +
Sbjct: 915 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 974
Query: 573 SNLEKDKEAEYAGQ---LAELRQRLDHAEADRQELQDELRQERE-------ARQKLEMMI 622
N K+ E AG +A+L + + Q+ D+L+ E + ++ KLE +
Sbjct: 975 -NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQV 1033
Query: 623 KELKLQILKSSK 634
+L+ + + K
Sbjct: 1034 DDLEGSLEQEKK 1045
Score = 38.5 bits (88), Expect = 0.019
Identities = 38/189 (20%), Positives = 85/189 (44%), Gaps = 23/189 (12%)
Query: 471 LVKDVICE-DDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSM--KELTE 527
L+KD + DD + +++ + + NL+ + ++L+ V+ S+ + +EL E
Sbjct: 1651 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1710
Query: 528 EQQNLQ-------------KELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSN 574
+ +Q K++ES + +EE E ++ E+K ++ +
Sbjct: 1711 TSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEE 1770
Query: 575 LEKDKEAEYAGQLAELRQRLDHAEADRQELQDE-----LRQEREARQKLEMMIKELKLQI 629
L+K+++ + L +++ ++ D Q DE L+ ++ QKLE ++EL+ ++
Sbjct: 1771 LKKEQDT--SAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGEL 1828
Query: 630 LKSSKTAKE 638
K E
Sbjct: 1829 EAEQKRNAE 1837
Score = 36.2 bits (82), Expect = 0.095
Identities = 38/170 (22%), Positives = 81/170 (47%), Gaps = 29/170 (17%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
E+DK ++ E++ ++++ ++ Q + +V L K +KE + L++ELE
Sbjct: 1072 ENDKLQLEEKL------KKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE 1125
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQ------KCTCDSNLEKDKEAEYAGQLAELR 591
+ + A ++E+ + DL ++LE+I ++ + + K +EAE+ +L
Sbjct: 1126 AERTARA-KVEKL---RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLE 1181
Query: 592 Q------------RLDHAEADRQELQDELRQEREARQKLEMMIKELKLQI 629
+ R HA++ EL +++ + +QKLE E KL++
Sbjct: 1182 EATLQHEATAAALRKKHADSVA-ELGEQIDNLQRVKQKLEKEKSEFKLEL 1230
Score = 33.5 bits (75), Expect = 0.62
Identities = 27/142 (19%), Positives = 64/142 (45%), Gaps = 10/142 (7%)
Query: 498 KLNLILQKKQQLQMEVKMLS-----SSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYV 552
K + + + K +LQ E++ L S+ + L ++Q+N K L + ++ + E
Sbjct: 1412 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1471
Query: 553 EQKDLEKKLEQIMKQKCTCDSNLE-----KDKEAEYAGQLAELRQRLDHAEADRQELQDE 607
QK+ ++ K K + +LE K + ++++L ++L + EL+
Sbjct: 1472 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKV 1531
Query: 608 LRQEREARQKLEMMIKELKLQI 629
+Q + +L+ ++E + +
Sbjct: 1532 RKQLEVEKLELQSALEEAEASL 1553
Score = 31.6 bits (70), Expect = 2.3
Identities = 39/213 (18%), Positives = 87/213 (40%), Gaps = 43/213 (20%)
Query: 429 EANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKI---- 484
EA S+++ +T + K ++ L R + + + +I + +GK+
Sbjct: 1267 EAQRSLNDFTTQRAKLQTENGELARQLEEK--------------EALISQLTRGKLSYTQ 1312
Query: 485 -MEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEH 543
ME++ R ++ + N + Q + + +L + +E TE + LQ+ L +E
Sbjct: 1313 QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLR--EQYEEETEAKAELQRVLSKANSEV 1370
Query: 544 AQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQE 603
AQ ++ + ++LE+ K +L QRL AE +
Sbjct: 1371 AQWRTKYETDAIQRTEELEEAKK----------------------KLAQRLQDAEEAVEA 1408
Query: 604 LQDELRQEREARQKLEMMIKELKLQILKSSKTA 636
+ + + + +L+ I++L + + +S+ A
Sbjct: 1409 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Score = 29.6 bits (65), Expect = 8.9
Identities = 27/132 (20%), Positives = 64/132 (48%), Gaps = 8/132 (6%)
Query: 505 KKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQI 564
+K + Q+EV+ L +++E ++ + ++ Q E Q E + + ++++EQ
Sbjct: 1529 EKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQA 1588
Query: 565 MKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDEL----RQEREARQK--- 617
+ +L+ +AE + LR + E D E++ +L R EA+++
Sbjct: 1589 KRNHQRVVDSLQTSLDAETRSRNEVLRVK-KKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
Query: 618 LEMMIKELKLQI 629
L+ ++K+ ++Q+
Sbjct: 1648 LQSLLKDTQIQL 1659
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 55.1 bits (131), Expect = 2e-07
Identities = 57/305 (18%), Positives = 136/305 (44%), Gaps = 39/305 (12%)
Query: 340 EEKKLKIILEEMKEKFSMRSGKRNQSKTDAPSGM-ELQSWYPVIKQEGDHVSQTHSFLHP 398
E+ +L++ L+E + + +R + +T A S + ++Q ++ E + VS + L
Sbjct: 883 EKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQ-----LETEKERVSLLETLLQT 937
Query: 399 SYYLYMCDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCNLVRDINKV 458
K +A + Q ++ K + + T ++++ R
Sbjct: 938 Q-------KELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDD 990
Query: 459 GIGLVAAASSPL------------LVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQK- 505
L +SS L L ++ +DD +++E+ ++ L++ ++ N I ++
Sbjct: 991 LAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKEL 1050
Query: 506 -KQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQI 564
+++ + + ++ + + L E Q+EL +L+ Q M+E EQK+L ++E +
Sbjct: 1051 EREKASLTLSLMEKEQRLLVLQEADSIRQQELSALR----QDMQEAQGEQKELSAQMELL 1106
Query: 565 MKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
++ K+KEA++ Q A+L + L+ + Q+L+ L + +L++ ++
Sbjct: 1107 RQEV--------KEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRS 1158
Query: 625 LKLQI 629
+ Q+
Sbjct: 1159 TESQL 1163
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/145 (28%), Positives = 68/145 (46%), Gaps = 20/145 (13%)
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 554
+QE + Q+K + EV L K KE + QQ L K LESL+ E +
Sbjct: 837 EQEGKTALEQQKAAHEKEVNQLRE-KWEKERSWHQQELAKALESLERE-----------K 884
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQER-- 612
+LE +L K++ T ++ +E E + L Q E +R L + L Q +
Sbjct: 885 MELEMRL----KEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKE 940
Query: 613 --EARQKLEMMIKELKLQILKSSKT 635
+A Q+LE + +++K+Q LK +T
Sbjct: 941 LADASQQLERLRQDMKVQKLKEQET 965
Score = 37.7 bits (86), Expect = 0.033
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 13/114 (11%)
Query: 519 SKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKD 578
++ + +L EE Q++ +E+ + Q V+ + EK+ E + ++ ++ L+K
Sbjct: 616 NQQLLQLEEENQSVCSRMEAAE----QARNALQVDLAEAEKRREALWEKNTHLEAQLQKA 671
Query: 579 KEAEYAGQLAELRQRLDHAEADRQELQDEL----RQEREARQKLEMMIKELKLQ 628
+EA AEL+ L + +++E+Q +L Q+ A +LE + +E K Q
Sbjct: 672 EEAG-----AELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQ 720
Score = 37.0 bits (84), Expect = 0.056
Identities = 39/183 (21%), Positives = 84/183 (45%), Gaps = 34/183 (18%)
Query: 480 DKGKIMEEVMRTYLKQQEKLNLI---------------LQKKQQLQMEVKMLSSSKSMKE 524
++ ++ E +M KQ E L+ + L +++Q ++ + + +S+ E
Sbjct: 520 ERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAE 579
Query: 525 LTEEQQNLQKELESLQNEHAQRM---EEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEA 581
L+ + L+ E+ L+ + E +++ L ++L Q+ ++ + S +E ++A
Sbjct: 580 LSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQA 639
Query: 582 EYAGQ--LAELRQRLD-------HAEADRQ-------ELQDELRQEREARQKLEMMIKEL 625
A Q LAE +R + H EA Q ELQ +LR +E +++++ + E
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Query: 626 KLQ 628
+ Q
Sbjct: 700 RHQ 702
Score = 36.6 bits (83), Expect = 0.073
Identities = 37/145 (25%), Positives = 74/145 (51%), Gaps = 15/145 (10%)
Query: 484 IMEEVMRTYLK----QQEKLNLILQKKQQLQMEVKM-LSSSKSMKE----LTEEQQNLQK 534
I+EE +RT + E++ ++ Q LQ + ++ ++ K+++E LT+ ++
Sbjct: 1376 ILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREE 1435
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRL 594
E+E+L+ + Q +E+ QK + L +K++ N E D + E +L + R L
Sbjct: 1436 EVETLRGQ-IQELEKQREMQKAALELLSLDLKKR-----NQEVDLQQEQIQELEKCRSVL 1489
Query: 595 DHAEADRQELQDELRQEREARQKLE 619
+H QE + +L +RE ++LE
Sbjct: 1490 EHLPMAVQEREQKLTVQREQIRELE 1514
Score = 36.2 bits (82), Expect = 0.095
Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Query: 493 LKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL---QKELESLQNE--HAQRM 547
L Q+E+ ++LQ++ Q E L +L E Q+ L +ELE+LQ E AQ
Sbjct: 1773 LSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQ 1832
Query: 548 EEFYVEQKD-LEKKLEQIMKQKCTCDSNLEKDKE--AEYAGQLAELRQRLDHAEADRQEL 604
EE E+ D L+ LEQ L+ KE +LA +R+ E +L
Sbjct: 1833 EERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDL 1892
Query: 605 QDELRQEREARQKLEMMIKE 624
+ E R++ +A L+ E
Sbjct: 1893 RAESREQEKALLALQQQCAE 1912
Score = 34.3 bits (77), Expect = 0.36
Identities = 26/121 (21%), Positives = 60/121 (49%), Gaps = 19/121 (15%)
Query: 520 KSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDK 579
+++++L ++ Q+ + LQ +H Q E E K L ++L+++ ++ T
Sbjct: 400 QAVQDLRQQLAGCQEAVNLLQQQHDQWEE----EGKALRQRLQKLTGERDT--------- 446
Query: 580 EAEYAGQLAELRQRLDHAEADRQELQ---DELRQEREARQKLEMMIKELKLQILKSSKTA 636
AGQ +L+ +D +R+ LQ +ELRQ+ E ++ ++ + +++ +A
Sbjct: 447 ---LAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSA 503
Query: 637 K 637
+
Sbjct: 504 Q 504
Score = 32.0 bits (71), Expect = 1.8
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQ-QLQMEVKMLSSSKSMKE------- 524
KD + E +G++ + ++ L E L L L++ +++ + K++ + +E
Sbjct: 1534 KDQMIESQRGQVQD--LKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALT 1591
Query: 525 -----LTEEQQNLQKE------LESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDS 573
L E Q LQ + LES A+ ++E E K +++E++ +QK
Sbjct: 1592 HLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQ 1651
Query: 574 NLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQ 610
+LE+ ++ E Q ++ D + L+++L Q
Sbjct: 1652 DLER-RDQELMLQKERIQVLEDQRTRQTKILEEDLEQ 1687
Score = 29.6 bits (65), Expect = 8.9
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 6/125 (4%)
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 554
Q+ + L +Q++Q ++E + ++ E + + +ES Q Q +++ V
Sbjct: 1497 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIES-QRGQVQDLKKQLVTL 1555
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA 614
+ L +LE+ K C L K+ E GQ R L H D +E EL+ +
Sbjct: 1556 ECLALELEE-NHHKMECQQKLIKELE----GQRETQRVALTHLTLDLEERSQELQAQSSQ 1610
Query: 615 RQKLE 619
LE
Sbjct: 1611 IHDLE 1615
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 54.7 bits (130), Expect = 3e-07
Identities = 47/175 (26%), Positives = 82/175 (46%), Gaps = 22/175 (12%)
Query: 478 EDDKGKIMEEV--MRTYLKQQEKLNLILQKKQ----QLQMEVKMLSSSKSMKELTEEQQN 531
E K ++ +E+ + L Q ++ L+KKQ QL E K +S+ + + E +
Sbjct: 1419 EKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEA 1478
Query: 532 LQKELESLQ-----NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSN---LEKDKEAEY 583
+KE ++L E + EEF + K L +E +M K N LEK K A
Sbjct: 1479 REKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA-- 1536
Query: 584 AGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
L Q+++ +EL+DEL+ +A+ +LE+ ++ +K Q + +T E
Sbjct: 1537 ------LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
Score = 49.3 bits (116), Expect = 1e-05
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 21/164 (12%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
K++ CE K++++V +++KL+ +Q ++ K+ + EL E+ L
Sbjct: 1234 KELACEV---KVLQQVKAESEHKRKKLDAQVQ-----ELHAKVSEGDRLRVELAEKASKL 1285
Query: 533 QKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEA--EYAGQLAEL 590
Q EL+++ +EE EKK + K + +S L+ +E E Q L
Sbjct: 1286 QNELDNVST----LLEE-------AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
Query: 591 RQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK 634
R+ E ++ LQ++ +E EAR+ LE + L+ Q+ + K
Sbjct: 1335 SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKK 1378
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/181 (22%), Positives = 91/181 (50%), Gaps = 30/181 (16%)
Query: 485 MEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMK-ELTEEQQNLQK---ELESLQ 540
+EE+ R + + E+ N++ + QLQ E ++ + ++ M+ L ++Q L++ +LES
Sbjct: 875 LEEMERKHQQLLEEKNILAE---QLQAETELFAEAEEMRARLAAKKQELEEILHDLESRV 931
Query: 541 NEHAQRMEEFYVEQK-------DLEKKLEQ-------IMKQKCTCDSNLEK--------- 577
E +R + E+K DLE++L++ + +K T ++ ++K
Sbjct: 932 EEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLE 991
Query: 578 DKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAK 637
D+ +++ + + R+ + E +++ + + R K E+MI +L+ ++ K KT +
Sbjct: 992 DQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ 1051
Query: 638 E 638
E
Sbjct: 1052 E 1052
Score = 43.5 bits (101), Expect = 6e-04
Identities = 41/168 (24%), Positives = 79/168 (47%), Gaps = 18/168 (10%)
Query: 483 KIMEEVMRTYLKQQE--------KLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQK 534
K+++ YLK + K+ +LQ +Q E ++ + + + ++ E+Q ++
Sbjct: 817 KVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQ---EEELQAKDEELLKVKEKQTKVEG 873
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRL 594
ELE ++ +H Q +EE + + L+ + E + + K +E E L +L R+
Sbjct: 874 ELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEI--LHDLESRV 931
Query: 595 DHAEADRQELQDELRQEREARQKLEMMIKE-----LKLQILKSSKTAK 637
+ E Q LQ+E ++ + Q LE + E KLQ+ K + AK
Sbjct: 932 EEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Score = 43.5 bits (101), Expect = 6e-04
Identities = 75/340 (22%), Positives = 140/340 (41%), Gaps = 55/340 (16%)
Query: 340 EEKKLKII-----LEEMKEKFSMRSGKRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHS 394
EE K K++ L + E+ ++ K ++K LQ + + DH Q S
Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN------RLQQELDDLTVDLDHQRQVAS 1444
Query: 395 FLHPSYYLYMCDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCNLVRD 454
L + D+++A S+++ ++ ++ + EA + + R E A +
Sbjct: 1445 NLEKKQKKF--DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEAL-EAKEE 1501
Query: 455 INKVGIGLVAAASSPLLVKDVI------CEDDKGKIMEEV--MRTYLKQ-QEKLNLILQK 505
+ L A + KD + E K + ++V MRT L++ +++L
Sbjct: 1502 FERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDA 1561
Query: 506 KQQLQMEVKMLSSSKSMKELTEEQQNLQK---------ELES-LQNEHAQRM------EE 549
K +L++ ++ + + T ++QN +K ELE+ L++E QR ++
Sbjct: 1562 KLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKK 1621
Query: 550 FYVEQKDLEKKLEQIMKQKCTCDSNLEK--------DKEAEYA--------GQLAELRQR 593
++ KDLE ++E K + L K +E E A Q E ++
Sbjct: 1622 MEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKK 1681
Query: 594 LDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSS 633
L EA+ +LQ+EL AR+ E EL +I S+
Sbjct: 1682 LKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/151 (20%), Positives = 69/151 (45%), Gaps = 18/151 (11%)
Query: 494 KQQEKLNLILQKKQQLQM---EVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRM--- 547
++Q L + +KK ++ + E ++ +++K+ E+ ++ + LQ +++ Q E +
Sbjct: 1609 RKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASR 1668
Query: 548 EEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDE 607
+E + + K+ EKKL+ + + L + A HAE +R EL DE
Sbjct: 1669 DEIFAQSKESEKKLKSLEAEILQLQEELASSERARR------------HAEQERDELADE 1716
Query: 608 LRQEREARQKLEMMIKELKLQILKSSKTAKE 638
+ + L + L+ +I + + +E
Sbjct: 1717 ITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
Score = 41.6 bits (96), Expect = 0.002
Identities = 48/180 (26%), Positives = 89/180 (49%), Gaps = 31/180 (17%)
Query: 481 KGKIMEEVMR---TYLKQQEKLNLILQ-KKQQLQMEVKMLSSSKSMKELTEEQQNLQK-E 535
K + +EE++ + ++++E+ N ILQ +K+++Q ++ L ++L EE+ QK +
Sbjct: 916 KKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLE-----EQLDEEEGARQKLQ 970
Query: 536 LESLQNE-HAQRMEEFYVEQKDL------EKKLEQIMKQKCTCDSNLEKDKEAEYAG--- 585
LE + E ++MEE + +D EKKL + +C+ E++K A
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 586 ----QLAELRQRLDHAEADRQELQ-------DELRQEREARQKLEMMIKELKLQILKSSK 634
+++L +RL E RQEL+ E ++ +L+ I ELKLQ+ K +
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/159 (25%), Positives = 81/159 (50%), Gaps = 21/159 (13%)
Query: 494 KQQEKLN-----LILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRME 548
+Q+E+L L+ K++Q ++E ++ + ++L EE+ L ++L++ + E E
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA-ETELFAEAE 907
Query: 549 EFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ---------LAELRQRLDHAEA 599
E +++LE+I+ +S +E+++E Q + +L ++LD E
Sbjct: 908 EMRARLAAKKQELEEILHD---LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG 964
Query: 600 DRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
RQ+LQ E + A K++ M +E+ L ++SK KE
Sbjct: 965 ARQKLQLE---KVTAEAKIKKMEEEILLLEDQNSKFIKE 1000
Score = 40.8 bits (94), Expect = 0.004
Identities = 36/151 (23%), Positives = 77/151 (50%), Gaps = 19/151 (12%)
Query: 503 LQKKQQLQMEVKMLSSSKSMKELTEEQQNLQK---ELESLQNEHAQRMEEFYVEQKDLEK 559
L+ K++ + + K L + M++L + ++ K ELE + Q++EE + ++LE
Sbjct: 1496 LEAKEEFERQNKQLRAD--MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553
Query: 560 KLEQIMKQKCTCDSNLEK-----DKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA 614
+L+ K + N++ +++ + + E ++RL + +EL+ EL ER+
Sbjct: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV--RELEAELEDERKQ 1611
Query: 615 R-------QKLEMMIKELKLQILKSSKTAKE 638
R +K+E+ +K+L+ QI ++K E
Sbjct: 1612 RALAVASKKKMEIDLKDLEAQIEAANKARDE 1642
Score = 40.4 bits (93), Expect = 0.005
Identities = 41/155 (26%), Positives = 75/155 (48%), Gaps = 34/155 (21%)
Query: 485 MEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA 544
+E+ + T QQE + K++Q E+K K L EE +N + +++ ++ HA
Sbjct: 1155 LEDTLDTTAAQQE----LRTKREQEVAELK--------KALEEETKNHEAQIQDMRQRHA 1202
Query: 545 QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEA------EYAGQLAELRQRLDHAE 598
+EE L ++LEQ + K +NLEK+K+ E A ++ L+Q +E
Sbjct: 1203 TALEE-------LSEQLEQAKRFK----ANLEKNKQGLETDNKELACEVKVLQQVKAESE 1251
Query: 599 ADRQELQDELRQ-----EREARQKLEMMIKELKLQ 628
R++L ++++ R ++E+ K KLQ
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286
Score = 36.6 bits (83), Expect = 0.073
Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 491 TYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQ---KELESLQNEHAQRM 547
T L++ EK + K +E ++ + + ++E T ++ NL ++LE +N ++
Sbjct: 1294 TLLEEAEKKGIKFAK-DAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQ 1352
Query: 548 EEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDE 607
EE +K+LEK++ + Q ++ D G + L + D + L
Sbjct: 1353 EEEEEARKNLEKQVLALQSQLADTKKKVDDD-----LGTIESLEEAKKKLLKDAEALSQR 1407
Query: 608 LRQEREARQKLEMMIKELKLQI 629
L ++ A KLE L+ ++
Sbjct: 1408 LEEKALAYDKLEKTKNRLQQEL 1429
Score = 35.0 bits (79), Expect = 0.21
Identities = 32/158 (20%), Positives = 76/158 (48%), Gaps = 10/158 (6%)
Query: 472 VKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQN 531
+KD E ++ + + + K+ EK L + + LQ++ ++ SS ++ + +E+
Sbjct: 1654 MKDYQRELEEARASRDEIFAQSKESEK-KLKSLEAEILQLQEELASSERARRHAEQERDE 1712
Query: 532 LQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELR 591
L E+ + + + ++E ++ LE ++ Q+ ++ SN+E + + +
Sbjct: 1713 LADEITNSASGKSALLDE----KRRLEARIAQLEEELEEEQSNMELLND-----RFRKTT 1763
Query: 592 QRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQI 629
++D A+ + ++ ARQ+LE KELK ++
Sbjct: 1764 LQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKL 1801
Score = 33.9 bits (76), Expect = 0.47
Identities = 29/142 (20%), Positives = 65/142 (45%), Gaps = 22/142 (15%)
Query: 518 SSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEK 577
+ K ++L+EE + L+ ELE + A + +E +++ +L++ ++++ +
Sbjct: 1137 AEKQKRDLSEELEALKTELEDTLDTTAAQ-QELRTKREQEVAELKKALEEETKNHEAQIQ 1195
Query: 578 DKEAEYAGQLAELRQRLDHA--------------EADRQELQDELR-------QEREARQ 616
D +A L EL ++L+ A E D +EL E++ + R+
Sbjct: 1196 DMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRK 1255
Query: 617 KLEMMIKELKLQILKSSKTAKE 638
KL+ ++EL ++ + + E
Sbjct: 1256 KLDAQVQELHAKVSEGDRLRVE 1277
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/160 (23%), Positives = 85/160 (53%), Gaps = 12/160 (7%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
+ ++ E+ + + +E R Y K+ E + Q+++QL E + + + E++ L
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDE----LQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 533 QKELESLQNEHA-----QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQL 587
Q+E E L E Q +E Y ++++L+++ EQ+++++ E++++ +L
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEEL 1116
Query: 588 AELRQRLDHAEAD---RQELQDELRQEREARQKLEMMIKE 624
+ ++L E + RQEL+ + R+E E +Q+ E +++E
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Score = 51.2 bits (121), Expect = 3e-06
Identities = 32/127 (25%), Positives = 62/127 (48%), Gaps = 10/127 (7%)
Query: 504 QKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDL------ 557
+K+QQ + + + KE + + L+KE E LQ E QR E E++ L
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 558 ----EKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQERE 613
E++ E+ +Q+ + L + +E E Q E R++ + E + + +LR+E+E
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 614 ARQKLEM 620
R++ ++
Sbjct: 345 ERREQQL 351
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/160 (21%), Positives = 85/160 (53%), Gaps = 12/160 (7%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
+ ++ E+ + + ++E R Y +++E + Q+++QL E + + ++ +++ L
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEE----LQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 533 QKELESLQNEHA-----QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQL 587
Q+E E L E Q E E+++L+++ EQ+++++ E +++ ++
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 588 AELRQRLDHAEAD---RQELQDELRQEREARQKLEMMIKE 624
+ ++L E + RQEL+ + R+E E +Q+ E +++E
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
Score = 47.4 bits (111), Expect = 4e-05
Identities = 37/160 (23%), Positives = 83/160 (51%), Gaps = 12/160 (7%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
+ ++ E+ + + +E R Y K ++ + QK++QL E + ++ E++ L
Sbjct: 941 EQLLREEREKRRRQERERQYRKDKK----LQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 533 QKELESLQNEHA-----QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQL 587
Q+E E L E Q E Y ++ +L+++ EQ+++++ E++++ +L
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 588 AELRQRLDHAEAD---RQELQDELRQEREARQKLEMMIKE 624
+ ++L E + RQEL+ + R+E E +Q+ E +++E
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Score = 46.6 bits (109), Expect = 7e-05
Identities = 39/161 (24%), Positives = 81/161 (50%), Gaps = 17/161 (10%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
+ ++ E+ + + +E+ R Y K++E + Q+++QL E + + E++ L
Sbjct: 1061 EQLLGEERETRRRQELERQYRKEEE----LQQEEEQLLREEPEKRRRQERERQCREEEEL 1116
Query: 533 QKELESLQNEHA-----QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQL 587
Q+E E L E Q +E Y E+++++++ EQ+++++ EK + E Q
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP------EKRRRQELERQY 1170
Query: 588 AELRQRLDHAEADRQELQDELRQEREA--RQKLEMMIKELK 626
E + E +E Q++ RQERE R++ E+ ++ K
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 16/147 (10%)
Query: 480 DKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESL 539
++ ++++E L++QE+ +++QQL+ + + K L EEQQ ++ELE
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ------ERERKFLQEEQQLRRQELERK 1724
Query: 540 QNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDS-------NLEKDKEAEYAGQLAELR- 591
E Q +E EQ +++ +I++++ E+D++ QL + R
Sbjct: 1725 FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 592 -QRLDHAEADRQELQDE-LRQEREARQ 616
Q+L E+DR+ ++E LRQERE +Q
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQ 1811
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/147 (28%), Positives = 72/147 (48%), Gaps = 12/147 (8%)
Query: 483 KIMEEVMRTYLKQQEKLNLILQKKQQLQMEVK--MLSSSKSMKELTEEQQNLQKELESLQ 540
K +EE R L++QE+ L+++QQL+ + + L + K EEQQ ++E +
Sbjct: 1375 KFLEEEQR--LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF 1432
Query: 541 NEHAQRMEEFYVEQKDL--EKKLEQIMKQKCTCDSNLEKDKE------AEYAGQLAELRQ 592
E Q++ E+K L E++L Q +K + L +++E E + E Q
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 593 RLDHAEADRQELQDELRQEREARQKLE 619
+L E DR+ + ELR + R+ LE
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLE 1519
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/138 (24%), Positives = 69/138 (50%), Gaps = 3/138 (2%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKE--LTEEQQNLQKELESLQNEHAQRMEEFY 551
+QQ + L+++QQL+ E ++ + +E L EQ+ + E + Q QR++
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 552 VEQKDLEKKLEQIMK-QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQ 610
E++D K+ E+ + ++ L++D+E E + +L + + +R+E Q Q
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 611 EREARQKLEMMIKELKLQ 628
E Q+L+ +E +LQ
Sbjct: 512 EERREQRLKRQEEEERLQ 529
Score = 43.5 bits (101), Expect = 6e-04
Identities = 41/150 (27%), Positives = 78/150 (52%), Gaps = 20/150 (13%)
Query: 483 KIMEEVMRTYLKQQEKLNLILQKKQQLQME--VKMLSSSKSMKELTEEQQNLQKELESLQ 540
K+ EE R +QQE+ L+++Q+ + E +K + +++ +Q L++E E +
Sbjct: 490 KLEEEERR---EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 541 NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAG----QLAELRQRLDH 596
+ +R EE +EQ+ E++L++ +++ D L++++E Q L QRL
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERR--DQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 597 AEADRQELQDELRQER--------EARQKL 618
E +R E Q+E R++R E RQ+L
Sbjct: 605 EEVERLE-QEERREQRLKREEPEEERRQQL 633
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/134 (22%), Positives = 74/134 (55%), Gaps = 8/134 (5%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVE 553
+++E+L ++K++ Q + + + +++ EE+Q L++E E + + +R Y +
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQ--EEEQLLREEREKRRRQERERQ---YRK 962
Query: 554 QKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD---RQELQDELRQ 610
K L++K EQ++ ++ E++K+ +L + ++L E + RQE + + R+
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 611 EREARQKLEMMIKE 624
+ E +Q+ E +++E
Sbjct: 1023 KDELQQEEEQLLRE 1036
Score = 43.1 bits (100), Expect = 8e-04
Identities = 33/146 (22%), Positives = 75/146 (51%), Gaps = 11/146 (7%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
E+++ ++ R +L+++++L + +Q+ Q + + +++ EEQQ L
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ-----LS 1573
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKL----EQIMKQKCTCDSNLEKDKEAEYAGQLAELR-- 591
+ + R+EE V +++ E+K +Q+ +Q+ E+D++ QL + R
Sbjct: 1574 RQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Query: 592 QRLDHAEADRQELQDELRQEREARQK 617
Q+L E DR+ L++E + R+ R++
Sbjct: 1634 QQLHRQERDRKFLEEEPQLRRQEREQ 1659
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 13/130 (10%)
Query: 508 QLQMEVKMLSSSKSMKELTEEQQN-----LQKELESLQNE-----HAQRMEEFYVEQKDL 557
QL+ E K + K +EQ LQ+E E LQ E Q E Y E++ L
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 558 EKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD---RQELQDELRQEREA 614
+++ EQ+++++ E++++ +L + ++L E + RQE + + R+E E
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 615 RQKLEMMIKE 624
+Q+ E +++E
Sbjct: 997 QQEEEQLLRE 1006
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/141 (25%), Positives = 76/141 (53%), Gaps = 10/141 (7%)
Query: 494 KQQEKLNLILQKKQQLQMEV----KMLSSSKSMKELTEE--QQNLQKELESLQNEHAQRM 547
+++E+L L+ +QQL+ E + L + K L +E +Q L++E E +++ +R
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 548 EEFYVE--QKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ--LAELRQRLDHAEADRQE 603
EE + +++ E++LEQ +K++ E+ +E + E RQ+L +E +
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 604 LQDELRQEREARQKLEMMIKE 624
Q +LR+E++ R++ + +E
Sbjct: 643 RQQQLRREQQERREQRLKREE 663
Score = 41.6 bits (96), Expect = 0.002
Identities = 25/151 (16%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
E+ + + E V+R K++EKL ++++ Q + ++ + +++L ++ +++ E
Sbjct: 242 EEKEWRKRETVLR---KEEEKL-----QEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
Q + +R ++ +Q++ ++ ++ +++ E+ +E + + E R++
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 598 EADRQELQDELRQEREARQKLEMMIKELKLQ 628
E + + + +LR+E+E ++ + + +E +L+
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLR 384
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/167 (21%), Positives = 87/167 (52%), Gaps = 14/167 (8%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
+ ++ E+ + + +E + Y +++E + Q+++QL E + + + ++ L
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEE----LQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 533 QKELESLQNEHA-----QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQL 587
Q+E E L E Q E Y E+++L+++ EQ++ ++ ++ ++ E +Y +
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER--ETRRRQELERQYRKE- 1083
Query: 588 AELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK 634
EL+Q + + R+E + RQERE + + E +++ + Q+L+ +
Sbjct: 1084 EELQQ--EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/156 (25%), Positives = 76/156 (48%), Gaps = 12/156 (7%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELES---LQNE 542
EE +LK +E+ Q++++ Q+ + + + EE++ LQ+ L S L+ E
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 543 HAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQ 602
+R E+ +++ EK+LEQ +++ L++++E L +R Q
Sbjct: 542 QEERREQLL--KREEEKRLEQERREQ-----RLKREQEERRDQLLKREEERRQQRLKREQ 594
Query: 603 ELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
E + E R +RE ++LE +E + Q LK + +E
Sbjct: 595 EERLEQRLKREEVERLEQ--EERREQRLKREEPEEE 628
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/143 (22%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
E+ K+ + +R +++E+ L+++QQL+ K + +E EQQ +++ E
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRR--KQEEERREQQEERREQQERREQQE 332
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ + +R +E E+++ + + EQ +++ + L +++E E Q Q+L
Sbjct: 333 ERREQQLRREQE---ERREQQLRREQEEERR---EQQLRREQEEERREQQLRREQQLRRE 386
Query: 598 EADRQELQDELRQEREARQKLEM 620
+ R+E Q LR+E++ R++ ++
Sbjct: 387 QQLRREQQ--LRREQQLRREQQL 407
Score = 40.8 bits (94), Expect = 0.004
Identities = 31/149 (20%), Positives = 73/149 (48%), Gaps = 17/149 (11%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
+E R +++EK L++++QLQ + ++L EE+ LQ++ E +++ +
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERA-------QQLQEEEDGLQEDQERRRSQEQR 869
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQ 605
R +++ + ++ K+ + K L K+++ L E + E R+E +
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL-----LQE-----EEEELQREERE 919
Query: 606 DELRQEREARQKLEMMIKELKLQILKSSK 634
RQE+E + + E +++ + Q+L+ +
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLREER 948
Score = 40.0 bits (92), Expect = 0.007
Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 18/134 (13%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
E +R +QQ + + +++++ Q + K ++ L EE+Q LQ+ E AQ
Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ-LQR------RERAQ 847
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQ 605
+++E E+ L++ E+ Q E+ ++ ++ QL E R+R H + LQ
Sbjct: 848 QLQE---EEDGLQEDQERRRSQ--------EQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 606 DELRQEREARQKLE 619
++LR+E++ Q+ E
Sbjct: 897 EQLRKEQQLLQEEE 910
Score = 40.0 bits (92), Expect = 0.007
Identities = 30/134 (22%), Positives = 71/134 (52%), Gaps = 13/134 (9%)
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 554
QQE+ L+ +++++ + + + K K +E+Q L +E E + Q E+ Y E+
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR---QEREKKYREE 993
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA 614
++L+++ EQ+++++ EK + E+ Q ++ D + + ++L E R++R
Sbjct: 994 EELQQEEEQLLREE------REKRRRQEWERQY----RKKDELQQEEEQLLREEREKRRL 1043
Query: 615 RQKLEMMIKELKLQ 628
+++ +E +LQ
Sbjct: 1044 QERERQYREEEELQ 1057
Score = 39.3 bits (90), Expect = 0.011
Identities = 29/150 (19%), Positives = 78/150 (52%), Gaps = 5/150 (3%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
++ + ++ K+ EE + + QE+ L+K ++ ++ + + + L EQQ
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQ-LRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 533 QKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMK-QKCTCDSNLEKDKEAEYAGQLAELR 591
+K+ E + + +R E+ ++ E++ +Q+ + Q+ + L +++E E Q +LR
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ--QLR 365
Query: 592 QRLDHAEADRQ-ELQDELRQEREARQKLEM 620
+ + ++Q + +LR+E++ R++ ++
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQL 395
Score = 39.3 bits (90), Expect = 0.011
Identities = 32/128 (25%), Positives = 63/128 (49%), Gaps = 8/128 (6%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEE--QQNLQKELESLQNEHAQRMEEFY 551
+QQE+ +++QQL+ E + + +E EE +Q L++E E + E R E+
Sbjct: 329 EQQEE-----RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 552 VEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQE 611
++ L ++ + +Q+ + L ++++ QL +Q E +R E + E ++
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE-QER 442
Query: 612 REARQKLE 619
RE R K E
Sbjct: 443 REQRLKRE 450
Score = 38.9 bits (89), Expect = 0.015
Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 7/144 (4%)
Query: 492 YLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFY 551
+L+++E+L ++ QQLQ E L + + ++EQ+ QK L+ E +R Y
Sbjct: 833 FLEEEEQLQR-RERAQQLQEEEDGLQEDQERRR-SQEQRRDQKWRWQLEEERKRRRHTLY 890
Query: 552 VE---QKDLEKKLEQIMKQKCTCD-SNLEKDKEAEYAGQLAELRQ-RLDHAEADRQELQD 606
+ Q+ L K+ + + +++ EK + E Q E Q + + + R+E +
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Query: 607 ELRQEREARQKLEMMIKELKLQIL 630
RQERE + + + +++ + Q+L
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLL 974
Score = 38.9 bits (89), Expect = 0.015
Identities = 28/160 (17%), Positives = 80/160 (50%), Gaps = 2/160 (1%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
+D K EE +++++L+ ++ ++ ++E + + + ++ E++Q L+++ E
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSR-QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ-E 1608
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
Q +R +F +++ L+++ EQ + ++ LE++ + + +LR D
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Query: 598 EADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAK 637
+ ++L E +++ RQ+ + +E + Q+ + + K
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Score = 38.5 bits (88), Expect = 0.019
Identities = 34/140 (24%), Positives = 69/140 (49%), Gaps = 29/140 (20%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNE-----HAQRME 548
+++E+L Q+++QL E + + ++ E++ +Q+E E L E Q +E
Sbjct: 1111 REEEELQ---QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 549 EFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDEL 608
Y E+++L+++ EQ++++ E++K RQ + + +ELQ
Sbjct: 1168 RQYREEEELQQEEEQLLRE--------EQEKR----------RQERERQYREEEELQ--- 1206
Query: 609 RQEREARQKLEMMIKELKLQ 628
RQ+R+ R + E +LK Q
Sbjct: 1207 RQKRKQRYRDEDQRSDLKWQ 1226
Score = 38.1 bits (87), Expect = 0.025
Identities = 36/154 (23%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEE---F 550
+QQ + L+++QQL+ E ++ + +E EE+ + E E + + EE +
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLE------KDKEAEYAGQLAELRQRLDHAEADR--- 601
+++ E+ ++ KQ+ D E K +E E Q Q+L + +R
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 602 ----QELQDELRQEREARQKLEMMIKELKLQILK 631
QE ++ L+Q + Q+L +E + Q+LK
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Score = 38.1 bits (87), Expect = 0.025
Identities = 34/129 (26%), Positives = 66/129 (51%), Gaps = 3/129 (2%)
Query: 493 LKQQEKLNLILQKKQQLQ-MEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFY 551
L++QE+ +++Q Q E + L S +S ++ EE+Q L++E E Q QR ++
Sbjct: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ-LRQEREEQQLRPQQRDGKYR 1822
Query: 552 VEQKDLE-KKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQ 610
E++ L+ ++ EQ ++Q+ E+ + + E + + RQE + +LR+
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 611 EREARQKLE 619
E RQ+ E
Sbjct: 1883 EHIRRQQKE 1891
Score = 37.7 bits (86), Expect = 0.033
Identities = 31/126 (24%), Positives = 69/126 (54%), Gaps = 17/126 (13%)
Query: 504 QKKQQLQMEVKMLSSSKS--MKELTEEQQNLQKEL--------ESLQNEHAQRMEEFYVE 553
Q++++ + E + L S K +E +E+Q ++EL E Q + +R + + E
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 554 QKDLE-KKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQER 612
+++ E +K E +++++ + L+++ E + +L E ++L E RQEL+ E ++E
Sbjct: 241 EEEKEWRKRETVLRKE---EEKLQEE-EPQRQRELQEEEEQLRKLE--RQELRRERQEEE 294
Query: 613 EARQKL 618
+ +Q+L
Sbjct: 295 QQQQRL 300
Score = 37.7 bits (86), Expect = 0.033
Identities = 39/147 (26%), Positives = 77/147 (52%), Gaps = 9/147 (6%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKE--LTEEQQNLQKELESLQNEHAQRMEEFY 551
+QQ + L+++QQL+ E ++ + +E L EQQ +++ + + + EE
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 552 VEQKDLEKKLEQIMKQKCTCDSN-LEKDKEAEYAGQLAELRQRLDHAEADRQE----LQD 606
EQK +++ EQ +K++ + L++++E E Q +Q E +R+E L++
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE 493
Query: 607 ELRQEREAR--QKLEMMIKELKLQILK 631
E R+E++ R Q+L +E + Q LK
Sbjct: 494 EERREQQERREQQLRREQEERREQRLK 520
Score = 37.4 bits (85), Expect = 0.043
Identities = 30/133 (22%), Positives = 66/133 (49%), Gaps = 11/133 (8%)
Query: 504 QKKQQLQMEVKMLSSSKSMKELTEE---------QQNLQKELESLQNEHAQRMEEFYVEQ 554
+++QQL+ E + + ++ EE +Q L++E + L+ E R E+ +
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE-QQLRREQQLRREQQLRRE 404
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA 614
+ L ++ + +Q+ + L +++E E Q E +R + +++E +D L++E E
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 615 -RQKLEMMIKELK 626
R + E ++LK
Sbjct: 465 ERHEQERRKQQLK 477
Score = 37.4 bits (85), Expect = 0.043
Identities = 30/159 (18%), Positives = 78/159 (49%), Gaps = 8/159 (5%)
Query: 477 CEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQ------ 530
C++ + ++ ++ R + +++++L+ + ++ + E ++ + K L EEQQ
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
Query: 531 -NLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAE 589
++E + LQ Q++ ++K LE++ +Q+ +Q+ ++ + E + E
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEE-QQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 590 LRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQ 628
Q+L + R+ LQ+E + R+ R + ++ K +
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Score = 36.6 bits (83), Expect = 0.073
Identities = 35/131 (26%), Positives = 67/131 (51%), Gaps = 14/131 (10%)
Query: 504 QKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQ 563
QK+Q+ + E+ +E +E+Q+ L++ ++E R + + E++ E++ E+
Sbjct: 139 QKRQEQERELA------EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE--ERRAEE 190
Query: 564 IMKQKCTCDSNLE-KDKEAEYAGQLAELRQR-LDHAEADRQELQDELRQEREARQ--KLE 619
Q C E D+E +L ELR++ + + R+E QD + QE E ++ K E
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE 250
Query: 620 MMIK--ELKLQ 628
+++ E KLQ
Sbjct: 251 TVLRKEEEKLQ 261
Score = 36.6 bits (83), Expect = 0.073
Identities = 34/142 (23%), Positives = 68/142 (47%), Gaps = 9/142 (6%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
E+++ + +E+ + Q+ L +L ++Q+ E + + + EE+Q LE
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ-----LE 1300
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ + A+R + E+K L ++ + +++ D K +E E Q E Q L
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETD---RKFREEEQLLQERE-EQPLRRQ 1356
Query: 598 EADRQELQDELRQEREARQKLE 619
E DR+ ++ELR + + R+ LE
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLE 1378
Score = 36.2 bits (82), Expect = 0.095
Identities = 33/147 (22%), Positives = 72/147 (48%), Gaps = 12/147 (8%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
EE +QE+ L+++Q+ + + E +Q L+++ E + E
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 546 RMEEFYVEQKDLEKKLEQIMK--QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQE 603
++EE E+++ +++ EQ ++ Q+ + L++ +E E L+QRL + R+E
Sbjct: 490 KLEE--EERREQQERREQQLRREQEERREQRLKRQEEEE------RLQQRLRSEQQLRRE 541
Query: 604 LQDELRQ--EREARQKLEMMIKELKLQ 628
++ Q +RE ++LE +E +L+
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLK 568
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/114 (28%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 525 LTEEQQNLQKELESLQNEHAQRMEEFYVEQKD--LEKKLEQIMKQKCTCDSNLEKDKEAE 582
L EE++ ESL + Q ++ E +D LE++ Q +QK E+++E
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQK-----RQEQERELA 149
Query: 583 YAGQLAELRQRLDHAEADRQELQDEL-RQEREARQKLEMMIKELKLQILKSSKT 635
+ +E ++RL+ + DRQ +EL RQ +E +++ E +E +LQ K +T
Sbjct: 150 EGEEQSEKQERLE--QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET 201
Score = 35.0 bits (79), Expect = 0.21
Identities = 26/126 (20%), Positives = 65/126 (51%), Gaps = 3/126 (2%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVE 553
++QE+ Q++++ Q E + + ++L EQ+ +++ + E +R ++ E
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 554 QKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQERE 613
Q++ ++ + +Q+ + L ++++ QL Q+L + R+E Q LR+E++
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQ--LRREQQ 424
Query: 614 ARQKLE 619
R++ E
Sbjct: 425 LRREQE 430
Score = 35.0 bits (79), Expect = 0.21
Identities = 34/171 (19%), Positives = 83/171 (48%), Gaps = 12/171 (7%)
Query: 476 ICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQ-QLQMEVKMLSSSKSMKELTEEQQNLQK 534
+ E+++ + E + K Q +L +Q ++ + + +E E+++ +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 535 ELESLQNEHAQRMEEFYVEQKDL------EKKLEQIMKQKCTCDSNLEKDKEAEYAGQLA 588
EL+ + E A R ++ +++D E+K E+ +Q+ + L + +E + A
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER-GRQRLSARPPLREQRERQLR---A 800
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQK-LEMMIKELKLQILKSSKTAKE 638
E RQ+ + +E +++ R++R R+K L+ + +E +LQ + ++ +E
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Score = 35.0 bits (79), Expect = 0.21
Identities = 27/130 (20%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Query: 493 LKQQEKLNLILQKKQQLQMEV--KMLSSSKSMKELTEEQQNLQ-KELESLQNEHAQRMEE 549
+++QE+ L+++QQL+ E K + ++E E+Q + Q ++ + L+ E R +E
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE 1498
Query: 550 FYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELR 609
+ ++ E + ++ ++ + L + + Q + +R + + RQ+ + R
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 610 QEREARQKLE 619
+E + RQ+ E
Sbjct: 1559 EEEQLRQERE 1568
Score = 34.7 bits (78), Expect = 0.28
Identities = 40/171 (23%), Positives = 83/171 (48%), Gaps = 28/171 (16%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE-------- 537
+++ R +++ + L L+++++ + + + + +E EQ+ ++E E
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 538 ---SLQNEHAQRMEEFYVEQKDLEKKLEQIMK-------QKCTCDSNLEKDKEAEY---- 583
L+ E +R E+ +++ EK+LEQ + Q+ D L++++E
Sbjct: 534 SEQQLRREQEERREQLL--KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 584 AGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK 634
Q L QRL E +R E Q+E R++R R++ E +E + Q+LKS +
Sbjct: 592 REQEERLEQRLKREEVERLE-QEERREQRLKREEPE---EERRQQLLKSEE 638
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 3/143 (2%)
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 554
++E+L Q ++ L+ E ++ + K L EEQQ +E E Q R +F E+
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE--QQLRQDRDRKFREEE 1420
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA 614
+ L ++ E+ K + +++E ++ + +LRQ + ++L E +++
Sbjct: 1421 QQLSRQ-ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1479
Query: 615 RQKLEMMIKELKLQILKSSKTAK 637
RQ+ + E + Q+ + + K
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRK 1502
Score = 33.9 bits (76), Expect = 0.47
Identities = 27/154 (17%), Positives = 77/154 (50%), Gaps = 11/154 (7%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
++ + +++ K +E R Y +++E L QK++Q + S K E +E
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEE---LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Query: 533 QKEL--ESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAEL 590
++ + +NE +++E+ + + ++ L+ ++ ++ E+D+E E
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ------QERDREQERRRWQQRD 1290
Query: 591 RQRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
R + + +R+E ++ R++R+++++ +++ +E
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Score = 33.9 bits (76), Expect = 0.47
Identities = 32/158 (20%), Positives = 80/158 (50%), Gaps = 5/158 (3%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
+E R +L+++ +L +++Q + + + + EEQQ ++E + E Q
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 546 RMEEFYVEQKDLEKKLE---QIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQ 602
++ E+K L+++ + Q +++K + L ++ E E + R+ L+ + +
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 603 ELQDEL-RQEREAR-QKLEMMIKELKLQILKSSKTAKE 638
+ +L RQER+ + ++ E + +E + Q L+S ++ ++
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Score = 32.7 bits (73), Expect = 1.1
Identities = 34/152 (22%), Positives = 72/152 (47%), Gaps = 17/152 (11%)
Query: 494 KQQEKLNLILQKKQQLQMEV--KMLSSSKSMKELTEEQQNLQK----ELESLQNEHAQRM 547
+Q EK + Q+ +Q + E + + +E E++ LQ E E +E R
Sbjct: 153 EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR 212
Query: 548 EEFY-VEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQD 606
E + +K E+K +Q +++ D ++++E E+ + LR+ + ++LQ+
Sbjct: 213 RELLELRRKGREEKQQQRRERQ---DRVFQEEEEKEWRKRETVLRK-------EEEKLQE 262
Query: 607 ELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
E Q + Q+ E +++L+ Q L+ + +E
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Score = 32.7 bits (73), Expect = 1.1
Identities = 37/177 (20%), Positives = 93/177 (52%), Gaps = 18/177 (10%)
Query: 473 KDVICEDDKGKIMEEVMRTYLK--QQEKLNLILQKKQQL-QMEVKMLSSSKSMKELT-EE 528
+ ++ +++ ++ +E LK Q+E+ + +L+++++ Q +K + + L EE
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 529 QQNLQKE------LESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAE 582
+ L++E L+ + E +R + E+++ ++ + +Q+ + L++++E E
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 583 YAGQLAELRQRLDHAEADR-QELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
E R + +H E R QEL +E ++ +AR++++ I + + Q L+S A++
Sbjct: 667 ----RLEQRLKREHEEERREQELAEE--EQEQARERIKSRIPKWQWQ-LESEADARQ 716
Score = 32.7 bits (73), Expect = 1.1
Identities = 34/143 (23%), Positives = 74/143 (51%), Gaps = 14/143 (9%)
Query: 493 LKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQ--QNLQKELESLQNEHAQRMEEF 550
L+++E+ L Q++ + E ++ + K L EEQ + ++E + L+ E R +E
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE- 1403
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDE--L 608
++ L + ++ +++ S E+D+ + E Q++ E +R+ L++E L
Sbjct: 1404 --REQQLRQDRDRKFREEEQQLSRQERDR------KFREEEQQVRRQERERKFLEEEQQL 1455
Query: 609 RQEREAR-QKLEMMIKELKLQIL 630
RQER + ++ E +++E + Q L
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQL 1478
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 53.9 bits (128), Expect = 4e-07
Identities = 42/173 (24%), Positives = 89/173 (51%), Gaps = 24/173 (13%)
Query: 490 RTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMK----ELTEEQQNLQKELESLQNEHAQ 545
R L Q+E+ LI + + L + SS +S+K LTE+++ L KE+ESL++
Sbjct: 1540 RLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIA 1599
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLE---------KDKEAEYAGQL-------AE 589
E+ + K+L+K+ E +++ + E + ++ E G+L E
Sbjct: 1600 ESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKE 1659
Query: 590 LRQRLDHAEADRQELQDELRQEREARQKLEMMIKE----LKLQILKSSKTAKE 638
++L AE + +E+++++R+ +++Q+ + ++E L+ ++ + TAKE
Sbjct: 1660 TEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKE 1712
Score = 42.4 bits (98), Expect = 0.001
Identities = 62/280 (22%), Positives = 122/280 (43%), Gaps = 38/280 (13%)
Query: 380 PVIKQEGDHVSQT--HSFLHPSYYLYMCD-KVVAPNVSLTSAVSQSKELT--KTEANASI 434
P+ K H +Q S L P + + D + S+ +Q KE+ K E +
Sbjct: 1266 PLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKV 1325
Query: 435 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIME-------- 486
S+ ++ K L INK G+ + + + +V E + K+
Sbjct: 1326 SSTTSELTKKSEEVFQLQEQINKQGLE-IESLKTVSHEAEVHAESLQQKLESSQLQIAGL 1384
Query: 487 EVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKE--LTE------EQQNLQK---- 534
E +R + ++L ++ KK++ +V LS S KE LT+ EQ++L K
Sbjct: 1385 EHLRELQPKLDELQKLISKKEE---DVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHT 1441
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRL 594
+LE EH +R+++ VE ++++K E+I + +S ++ + + L ++ L
Sbjct: 1442 QLEMQAKEHDERIKQLQVELCEMKQKPEEIGE-----ESRAKQQIQRKLQAALISRKEAL 1496
Query: 595 DHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK 634
+ + LQ+EL R ++L + +++ Q+ +K
Sbjct: 1497 ----KENKSLQEELSLARGTIERLTKSLADVESQVSAQNK 1532
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/133 (21%), Positives = 68/133 (51%), Gaps = 10/133 (7%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVE 553
K++ + L KK+ Q + K+ ++ + KEL + L++EL +L++E + + E
Sbjct: 974 KEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETE 1033
Query: 554 QKDLEK-KLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQER 612
+ ++E+ K + +KC K +E E L+Q + E + Q ++ +L ++
Sbjct: 1034 RGEVEEDKENKEYSEKCV----TSKCQEIE-----IYLKQTISEKEVELQHIRKDLEEKL 1084
Query: 613 EARQKLEMMIKEL 625
A ++ + ++K++
Sbjct: 1085 AAEEQFQALVKQM 1097
Score = 38.9 bits (89), Expect = 0.015
Identities = 35/168 (20%), Positives = 77/168 (45%), Gaps = 6/168 (3%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQM--EVKMLSSSKSMKELTEEQQ 530
+++ ++D ++++ +R E+L + + + + + E K + + +++ + Q
Sbjct: 2224 EEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQ 2283
Query: 531 NLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE--AEYAGQLA 588
KEL S E E LE +L+ + Q ++LEK KE G +
Sbjct: 2284 GENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIR 2343
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQKL--EMMIKELKLQILKSSK 634
+ + +++ ++L+ +L+ RE +L E+ +KE K+ L S K
Sbjct: 2344 QQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGK 2391
Score = 38.1 bits (87), Expect = 0.025
Identities = 36/188 (19%), Positives = 86/188 (45%), Gaps = 31/188 (16%)
Query: 478 EDDKGKIMEEV------MRTYLKQQEKLNLILQK-KQQLQMEVKMLSSSKSMKELTEEQ- 529
E++K ++ ++ ++ ++ K+NL+ Q+ +++L K+ +++ K+ EE+
Sbjct: 1867 ENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1926
Query: 530 QNLQKELESLQNEHAQRMEEFYVEQK--------------DLEKKLEQIMKQKCTCDSNL 575
N EL + Q + + ++ + +LE++ +Q++K+K +S +
Sbjct: 1927 MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1986
Query: 576 EKD---------KEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELK 626
K+ KE EL++ L + + ++LQ + + +E LE +K L+
Sbjct: 1987 RKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2046
Query: 627 LQILKSSK 634
+S K
Sbjct: 2047 FVQTESQK 2054
Score = 38.1 bits (87), Expect = 0.025
Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 44/194 (22%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQ--KKQQLQMEVKMLSSSKSM------------- 522
E+++ ++EE + + + +L L+ KK+ +Q + ++ S KSM
Sbjct: 2420 EEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGD 2479
Query: 523 --------------------------KELTEEQQNLQKELESLQNEHAQRMEEFYVEQKD 556
+L EE + L+ ++ L +E+A+ E ++D
Sbjct: 2480 YQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRED 2539
Query: 557 LEKKLE-QIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREAR 615
L + + + +QK + L+++KE E + A+L ++L +E ++L+ +E +
Sbjct: 2540 LNQVITIKDSQQKQLLEVQLQQNKELE--NKYAKLEEKLKESEEANEDLRRSFNALQEEK 2597
Query: 616 QKLEMMIKELKLQI 629
Q L I+ LK+ I
Sbjct: 2598 QDLSKEIESLKVSI 2611
Score = 36.6 bits (83), Expect = 0.073
Identities = 50/306 (16%), Positives = 131/306 (42%), Gaps = 31/306 (10%)
Query: 349 EEMKEKFSMRSGKRNQSKTDAPSGM----ELQSWYPVIKQEGDHVSQT--HSFLHPSYYL 402
E+++E + SG + +P+G ELQ + ++K+E + + + ++ L
Sbjct: 947 EQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELL 1006
Query: 403 YMCDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGL 462
++ +L + L++TE + + +K SE + ++I
Sbjct: 1007 QRVSRLEEELANLKDESKKEIPLSETE-RGEVEEDKENKEYSEKCVTSKCQEIEIYLKQT 1065
Query: 463 VAAASSPL------LVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKML 516
++ L L + + E+ +++++ +T + +++L+ + + Q ++ L
Sbjct: 1066 ISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL 1125
Query: 517 SSSKS----------MKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMK 566
+S + +KE E + E +++ E++ L+KKL++ +
Sbjct: 1126 ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALT 1185
Query: 567 QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELK 626
+ + L+K +E E LR+ L + D LQ++ ++ + + + +++L+
Sbjct: 1186 SR---KAILKKAQEKE-----RHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1237
Query: 627 LQILKS 632
+Q+ +S
Sbjct: 1238 IQVRES 1243
Score = 36.2 bits (82), Expect = 0.095
Identities = 38/155 (24%), Positives = 75/155 (48%), Gaps = 11/155 (7%)
Query: 487 EVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQR 546
++++ L E+ N IL ++ Q QME + + +++ EE + L LE ++ E A+R
Sbjct: 276 DLLQQELTAAEQRNQILSQQLQ-QMEAEHNTLRNTVETEREESKIL---LEKMELEVAER 331
Query: 547 MEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDH---AEADRQE 603
F+ Q+++ LEQ +Q + LE A AE+ ++ H + QE
Sbjct: 332 KLSFHNLQEEMHHLLEQ-FEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQE 390
Query: 604 LQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
LQ ++ KL +++ Q ++S++T ++
Sbjct: 391 LQSACDALKDQNSKL---LQDKNEQAVQSAQTIQQ 422
Score = 36.2 bits (82), Expect = 0.095
Identities = 67/326 (20%), Positives = 124/326 (38%), Gaps = 38/326 (11%)
Query: 332 NQKYLGTPEEKKLKII-LEEMKEKF-----SMRSGKRNQSKTDAPSGMELQSWYPVIKQE 385
NQ + E KL + L E KEK S++S K +S ELQ Y ++ Q
Sbjct: 1562 NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQS 1621
Query: 386 GDHVS-QTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKS 444
++VS + H + + + + T A + E EA + RK
Sbjct: 1622 YENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF 1681
Query: 445 ESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQ 504
+ + ++ + L A D + ME ++ + +E+L +
Sbjct: 1682 AKSKQQKILELEEENDRLRAEVHP--------AGDTAKECMETLLSSNASMKEELERVKM 1733
Query: 505 KKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA--QRMEEFYVEQKDLEKKLE 562
+ + L + + L S K L+EE Q+L+ ++E ++ A + E+ + E+ +
Sbjct: 1734 EYETLSKKFQSLMSEKD--SLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQ 1791
Query: 563 QI-----------MKQKCTCDSNLEKDKEAEYA--------GQLAELRQRLDHAEADRQE 603
I M + TC ++ K A A ++ Q++D +
Sbjct: 1792 SIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAG 1851
Query: 604 LQDELRQEREARQKLEMMIKELKLQI 629
L++E ++ +E Q LE L QI
Sbjct: 1852 LEEEKQKNKEFSQTLENEKNTLLSQI 1877
Score = 36.2 bits (82), Expect = 0.095
Identities = 41/179 (22%), Positives = 81/179 (45%), Gaps = 33/179 (18%)
Query: 480 DKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE-- 537
+K K+ E+ + YL +K Q Q E S +K ++EL +E+Q K+L+
Sbjct: 1978 EKTKVESEIRKEYL----------EKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKD 2027
Query: 538 --------SLQNEHAQRMEEFYVE-QKDLE---KKLEQIMKQKCTCDSNLEK------DK 579
S + +E E QKDLE + L Q ++ + + L D
Sbjct: 2028 CIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDT 2087
Query: 580 EAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
++E A LA+ + +++++ ++ +++Q+ E LE +++ + + LK K +E
Sbjct: 2088 QSEAARVLADNLKLKKELQSNKESVKSQMKQKDE---DLERRLEQAEEKHLKEKKNMQE 2143
Score = 36.2 bits (82), Expect = 0.095
Identities = 33/175 (18%), Positives = 80/175 (45%), Gaps = 31/175 (17%)
Query: 480 DKGKIMEEVMRTYLKQQEKLNLI---------LQKKQQLQMEVKMLSSSKSMKELTEEQQ 530
+K + ++++ + ++ QEK++ + +Q + Q +E+ + +++ + E ++
Sbjct: 2016 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEI----TKENLAQAVEHRK 2071
Query: 531 NLQKELESL-------QNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEY 583
Q EL S Q+E A+ + + +K+L+ E + Q D +LE+
Sbjct: 2072 KAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER------ 2125
Query: 584 AGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
L Q + +++ +Q++L R + LE I E+++ + K K ++
Sbjct: 2126 -----RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQ 2175
Score = 35.4 bits (80), Expect = 0.16
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Query: 509 LQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQK 568
++ME K+L +K K LT + Q+ + + SLQN EE ++ + L+++ + K
Sbjct: 2713 VEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK 2772
Query: 569 CTCDSNLEKD---KEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLE 619
N E+D E ++ E L H E Q+L + Q +LE
Sbjct: 2773 EQGLLNRERDALLSETAFSMNSTE-ENSLSHLEKLNQQLLSKDEQLLHLSSQLE 2825
Score = 35.0 bits (79), Expect = 0.21
Identities = 40/163 (24%), Positives = 79/163 (48%), Gaps = 14/163 (8%)
Query: 485 MEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQ----KELESLQ 540
+EE Y Q +L + + + L+ ++ LS+S +++ E++ NL+ ++ +Q
Sbjct: 2293 LEETRHLYHSSQNELAKLESELKSLKDQLTDLSNS--LEKCKEQKGNLEGIIRQQEADIQ 2350
Query: 541 NEHA--QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAE 598
N +++E ++L +L + + K +L KE +AELRQ+ D
Sbjct: 2351 NSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD--- 2407
Query: 599 ADRQELQDELRQEREARQKLEMMIK---ELKLQILKSSKTAKE 638
+ +EL++ L QE E LE K + Q++++ KT K+
Sbjct: 2408 KEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKK 2450
Score = 33.5 bits (75), Expect = 0.62
Identities = 43/198 (21%), Positives = 81/198 (40%), Gaps = 19/198 (9%)
Query: 421 QSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDD 480
Q+KE E + + S+ + A +I K+ L+ ++ I E D
Sbjct: 841 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKD 900
Query: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQ 540
++V EK+ + ++K L +E+K L ++ EE + Q E +
Sbjct: 901 -----QQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEED--- 952
Query: 541 NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQL-------AELRQR 593
NE + +++ Y E QI K++ + +L K + + +L EL QR
Sbjct: 953 NEVSSGLKQNYDEM----SPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1008
Query: 594 LDHAEADRQELQDELRQE 611
+ E + L+DE ++E
Sbjct: 1009 VSRLEEELANLKDESKKE 1026
Score = 32.7 bits (73), Expect = 1.1
Identities = 32/141 (22%), Positives = 57/141 (40%), Gaps = 18/141 (12%)
Query: 485 MEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA 544
M L EKLN +Q L + ++L S +++ + Q+ K + SLQNE
Sbjct: 2792 MNSTEENSLSHLEKLN-----QQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERD 2846
Query: 545 QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQEL 604
E +K E K ++ Q T + ++ L++ + + DR L
Sbjct: 2847 HLWNELEKFRKSEEGK-QRSAAQPSTSPAEVQ------------SLKKAMSSLQNDRDRL 2893
Query: 605 QDELRQEREARQKLEMMIKEL 625
EL+ ++ ++ I EL
Sbjct: 2894 LKELKNLQQQYLQINQEITEL 2914
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 15/147 (10%)
Query: 491 TYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEF 550
T Q+K L +Q +Q ++E K + +KE E ++L++ +LQ E ++
Sbjct: 2545 TIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEE----KQDL 2600
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQL---AELRQRLDHAEADRQELQDE 607
E + L+ + Q+ +Q E+ Y QL E RL + Q+ E
Sbjct: 2601 SKEIESLKVSISQLTRQVTALQ---EEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAE 2657
Query: 608 LRQE-----REARQKLEMMIKELKLQI 629
L +E +EA +K+ + +LK ++
Sbjct: 2658 LEEELVCVQKEAAKKVGEIEDKLKKEL 2684
Score = 31.2 bits (69), Expect = 3.1
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 20/114 (17%)
Query: 517 SSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLE 576
S K+M L ++ L KEL++LQ ++ Q +E E L+ +L++
Sbjct: 2878 SLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEI-TELHPLKAQLQEY------------ 2924
Query: 577 KDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQIL 630
+DK + ELRQ + Q EL Q R + E+ + +K Q L
Sbjct: 2925 QDKTKAFQIMQEELRQ-------ENLSWQHELHQLRMEKSSWEIHERRMKEQYL 2971
Score = 30.8 bits (68), Expect = 4.0
Identities = 53/273 (19%), Positives = 106/273 (38%), Gaps = 28/273 (10%)
Query: 341 EKKLKIILEEMKEKFSMRSGKRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSY 400
+ K + ILE +E +R+ T L S +K+E + V + L +
Sbjct: 1683 KSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKF 1742
Query: 401 YLYMCDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGI 460
M +K SL+ V K + E N S N + K ++ T N+ + +
Sbjct: 1743 QSLMSEKD-----SLSEEVQDLKH--QIEGNVSKQANLEATEKHDNQT-NVTEEGTQSIP 1794
Query: 461 GLVAAASSPLLVKDVICEDD--KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSS 518
G S + C + K + +++N LQ+ QL+ + L
Sbjct: 1795 GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLE- 1853
Query: 519 SKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKD 578
EE+Q ++ ++L+NE + + + +L+ E++ K NL
Sbjct: 1854 --------EEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM------NLLNQ 1899
Query: 579 KEAEYAGQLAELRQRLDHAEADRQELQDELRQE 611
+ E ++ +L++ AE ++ +L++ L +
Sbjct: 1900 QIQEELSRVTKLKET---AEEEKDDLEERLMNQ 1929
Score = 30.4 bits (67), Expect = 5.2
Identities = 25/142 (17%), Positives = 64/142 (45%), Gaps = 8/142 (5%)
Query: 487 EVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQR 546
E+ R ++ ++KL ++ ++ + L +++ S +SM L + + +EL+ L+ ++
Sbjct: 2707 ELARDLVEMEQKLLMVTKENKGLTAQIQ--SFGRSMSSLQNSRDHANEELDELKRKYDAS 2764
Query: 547 MEEF--YVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQEL 604
++E EQ L ++ + ++ + ++ E++ L +L Q+L + L
Sbjct: 2765 LKELAQLKEQGLLNRERDALLSETAFSMNSTEENS----LSHLEKLNQQLLSKDEQLLHL 2820
Query: 605 QDELRQEREARQKLEMMIKELK 626
+L Q + L+
Sbjct: 2821 SSQLEDSYNQVQSFSKAMASLQ 2842
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 53.5 bits (127), Expect = 6e-07
Identities = 50/220 (22%), Positives = 102/220 (46%), Gaps = 15/220 (6%)
Query: 424 ELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGK 483
E+ T I + + AT + D NK+ + A S + ++ + K
Sbjct: 687 EIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAM-------KEMEKK 739
Query: 484 IMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEH 543
++EE RT ++ E L L +K+ L ++ + S + + EL +++ L +++ +L +
Sbjct: 740 LLEE--RTLKQKVENLLLEAEKRCSL-LDCDLKQSQQKINELLKQKDVLNEDVRNLTLKI 796
Query: 544 AQRMEEFYVEQKDLEKKLEQIMKQKCT-----CDSNLEKDKEAEYAGQLAELRQRLDHAE 598
Q ++ + Q DL+ + +Q+ K + ++N + + Q AELR+ A+
Sbjct: 797 EQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDAD 856
Query: 599 ADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
+ELQD+L E+ + ++ELK + + +K KE
Sbjct: 857 GQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKE 896
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/261 (20%), Positives = 113/261 (43%), Gaps = 37/261 (14%)
Query: 409 VAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAA-- 466
+A + ++ ++K E + T K+K E+ + + + L +
Sbjct: 715 LADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQK 774
Query: 467 -SSPLLVKDVICEDDKG---KIMEEVMRTYLKQQE------KLNLILQKKQQLQ------ 510
+ L KDV+ ED + KI +E + L Q + ++N + ++QL+
Sbjct: 775 INELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHL 834
Query: 511 MEVKMLSSSKSMKELTEEQQNLQKELESLQN--EHAQRMEEFYVEQ-------------- 554
ME+KM + K EL +E+Q+ +++ LQ+ E Q Y Q
Sbjct: 835 MEMKM-NLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKL 893
Query: 555 -KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELR-QER 612
K+L++K +++ ++ + + LE + QLA +++ +++++ EL +E
Sbjct: 894 GKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEM 953
Query: 613 EARQKLEMMIKELKLQILKSS 633
AR K E+ K+ + L+ +
Sbjct: 954 MARHKQELTEKDATIASLEET 974
Score = 40.4 bits (93), Expect = 0.005
Identities = 40/191 (20%), Positives = 85/191 (44%), Gaps = 24/191 (12%)
Query: 449 CNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQ 508
C L D+ I L +++ + +K K E+ TY +L +I Q +Q
Sbjct: 649 CGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTY-----QLKVIQQSLEQ 703
Query: 509 LQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIM--- 565
+ E K+ K ++ + + +E ++E + ME+ +E++ L++K+E ++
Sbjct: 704 EEAE------HKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEA 757
Query: 566 KQKCT---CDSNLEKDKEAEYAGQ-------LAELRQRLDHAEADRQELQDELRQEREAR 615
+++C+ CD + K E Q + L +++ R Q++L+ + +
Sbjct: 758 EKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQV 817
Query: 616 QKLEMMIKELK 626
L+M K+LK
Sbjct: 818 NTLKMSEKQLK 828
Score = 35.0 bits (79), Expect = 0.21
Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 41/180 (22%)
Query: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSS--SKSMKELTEE---------- 528
K + +E+ + +E L+ +Q K++L+ + K +++ K+ KEL EE
Sbjct: 438 KNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESA 497
Query: 529 QQNLQKELESLQNEHA--QRMEEFYVEQK---------------DLEK----------KL 561
+ L++E LQ+++A QR + ++K DL+K K+
Sbjct: 498 LRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKV 557
Query: 562 EQIMKQKCTCDSNL--EKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLE 619
Q+ +Q ++ L E D A AE +++ E++ ++LQD+ A+ KLE
Sbjct: 558 NQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLE 617
Score = 31.2 bits (69), Expect = 3.1
Identities = 41/188 (21%), Positives = 91/188 (48%), Gaps = 33/188 (17%)
Query: 480 DKGKIMEEVMRTYLKQQEKLNL---------ILQKKQQLQMEVKMLSSSKSMKELTEEQQ 530
+K KIM+E+ + + K L + + + L +V L++ K +EL + +
Sbjct: 940 EKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEK--EELNNKLK 997
Query: 531 NLQKELESLQNEHAQ------RMEEFYVEQKDLE----KKLEQIMKQKCTC----DSNLE 576
++Q++L L++E + E+ + ++ L+ KL +IM +K D+++
Sbjct: 998 DVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVR 1057
Query: 577 -KDKE-----AEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMI--KELKLQ 628
K+KE E + +L Q++ + + E+Q ++ +E + R +L+M + K+ ++
Sbjct: 1058 RKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIE 1117
Query: 629 ILKSSKTA 636
L+S A
Sbjct: 1118 QLRSQLQA 1125
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 53.1 bits (126), Expect = 8e-07
Identities = 50/253 (19%), Positives = 118/253 (46%), Gaps = 24/253 (9%)
Query: 405 CDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVA 464
CD+++ + L + V + E + E + + + KRK E L RDI+ + + L
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMN-AELTAKKRKLEDECSELKRDIDDLELTLAK 963
Query: 465 AASSPLLVKDVI---CEDDKG------------KIMEEVMRTYLK----QQEKLNLILQK 505
++ + E+ G K ++E + L +++K+N + +
Sbjct: 964 VEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 506 KQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIM 565
K +L+ +V L S +++ + + +L++ L+ + E + D ++ E++
Sbjct: 1024 KVKLEQQVDDLEGS--LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK 1081
Query: 566 KQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKEL 625
K+ ++ + ++ + G ++L+++L +A +EL++EL ER AR K+E + +L
Sbjct: 1082 KKDFELNALNARIEDEQALG--SQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 626 KLQILKSSKTAKE 638
++ + S+ +E
Sbjct: 1140 SRELEEISERLEE 1152
Score = 43.9 bits (102), Expect = 5e-04
Identities = 50/205 (24%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Query: 429 EANASISNNSTSKRKSESATCNLVRDINKVGIGLVAA--ASSPLLVKDVICEDDKGKIME 486
E + T++ K E +L R++ ++ L A A+S + + E + K+
Sbjct: 1117 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1176
Query: 487 EVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQR 546
++ L Q E L+KK + S+ EL E+ NLQ+ + L+ E +
Sbjct: 1177 DLEEATL-QHEATAAALRKKH-----------ADSVAELGEQIDNLQRVKQKLEKEKS-- 1222
Query: 547 MEEFYVEQKDLEKKLEQIMKQKCTCDSNLEK------DKEAEYAGQLAELRQRLDHAEAD 600
EF +E D+ +EQI+K K +NLEK D+ E+ + E ++ ++ +
Sbjct: 1223 --EFKLELDDVTSNMEQIIKAK----ANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 601 RQELQDELRQEREARQKLEMMIKEL 625
R +LQ E + + E +I +L
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQL 1301
Score = 38.9 bits (89), Expect = 0.015
Identities = 38/171 (22%), Positives = 74/171 (43%), Gaps = 33/171 (19%)
Query: 496 QEKLNLILQKKQQLQMEV----------------------KMLSSSKSMKELTEEQQNLQ 533
+EK+ +LQ+K LQ++V ++ + K M E E+++ +
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 534 KELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ---LAEL 590
EL + + + E + DLE L ++ K+K + N K+ E AG +A+L
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE-NKVKNLTEEMAGLDEIIAKL 992
Query: 591 RQRLDHAEADRQELQDELRQERE-------ARQKLEMMIKELKLQILKSSK 634
+ + Q+ D+L+ E + A+ KLE + +L+ + + K
Sbjct: 993 TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKK 1043
Score = 38.5 bits (88), Expect = 0.019
Identities = 40/170 (23%), Positives = 82/170 (48%), Gaps = 29/170 (17%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
E+DK ++ E + + + LN ++ +Q L +++ K +KEL + L++ELE
Sbjct: 1070 ENDKQQLDERLKKKDF-ELNALNARIEDEQALGSQLQ-----KKLKELQARIEELEEELE 1123
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQ------KCTCDSNLEKDKEAEYAGQLAELR 591
+ + A ++E+ + DL ++LE+I ++ + + K +EAE+ +L
Sbjct: 1124 AERTARA-KVEKL---RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLE 1179
Query: 592 Q------------RLDHAEADRQELQDELRQEREARQKLEMMIKELKLQI 629
+ R HA++ EL +++ + +QKLE E KL++
Sbjct: 1180 EATLQHEATAAALRKKHADSVA-ELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Score = 37.4 bits (85), Expect = 0.043
Identities = 34/150 (22%), Positives = 67/150 (44%), Gaps = 19/150 (12%)
Query: 492 YLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE----SLQNEHAQRM 547
++K K+ +L+ ++ + M +KE E+ + +KELE SL E
Sbjct: 829 WMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888
Query: 548 EEFYVEQ---KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQEL 604
+ EQ D E++ +Q++K K ++ ++ E+ +RL+ E EL
Sbjct: 889 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVK------------EMNERLEDEEEMNAEL 936
Query: 605 QDELRQEREARQKLEMMIKELKLQILKSSK 634
+ R+ + +L+ I +L+L + K K
Sbjct: 937 TAKKRKLEDECSELKRDIDDLELTLAKVEK 966
Score = 33.9 bits (76), Expect = 0.47
Identities = 27/142 (19%), Positives = 64/142 (45%), Gaps = 10/142 (7%)
Query: 498 KLNLILQKKQQLQMEVKMLS-----SSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYV 552
K + + + K +LQ E++ L S+ + L ++Q+N K L + ++ + E
Sbjct: 1410 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1469
Query: 553 EQKDLEKKLEQIMKQKCTCDSNLE-----KDKEAEYAGQLAELRQRLDHAEADRQELQDE 607
QK+ ++ K K + +LE K + ++++L ++L + EL+
Sbjct: 1470 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV 1529
Query: 608 LRQEREARQKLEMMIKELKLQI 629
+Q + +L+ ++E + +
Sbjct: 1530 RKQLEAEKMELQSALEEAEASL 1551
Score = 31.2 bits (69), Expect = 3.1
Identities = 37/176 (21%), Positives = 72/176 (40%), Gaps = 46/176 (26%)
Query: 479 DDKGKIMEEVMR---TYLKQQEKLNLILQKKQQLQMEVKMLSS---------------SK 520
D+K ++ ++ R TY +Q E L K+QL+ EVK ++ +
Sbjct: 1292 DEKEALISQLTRGKLTYTQQLEDL------KRQLEEEVKAKNALAHALQSARHDCDLLRE 1345
Query: 521 SMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE 580
+E TE + LQ+ L +E AQ ++ + ++LE+ K
Sbjct: 1346 QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK-------------- 1391
Query: 581 AEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTA 636
+L QRL AE + + + + + +L+ I++L + + +S+ A
Sbjct: 1392 --------KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1439
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/164 (26%), Positives = 77/164 (46%), Gaps = 15/164 (9%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNE--H 543
EE+ K QEKL L+ +K ++Q+ VK L +L QQ LQ E + L E
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 544 AQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQE 603
+ VE+ +L +L Q ++K +++K E+ ++ E +++ E +E
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMW----RQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 604 LQDELRQERE---------ARQKLEMMIKELKLQILKSSKTAKE 638
++++R++ E RQ+ M KE K++ L+ KE
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
Score = 43.5 bits (101), Expect = 6e-04
Identities = 33/160 (20%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQL-QMEVKMLSSSKSM---KELTEE 528
++ I E ++ + EE +R K+QE+ + ++++++ + E K+ K M +E E
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 448
Query: 529 QQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSN----LEKDKEAEYA 584
Q+ +++E + + E R EE EQ+++ ++ E++ +Q+ +++K +
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE 508
Query: 585 GQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
++ E +++ E +E ++++R++ E ++ E M++E
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/162 (22%), Positives = 83/162 (51%), Gaps = 14/162 (8%)
Query: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTE------EQQNLQK 534
+ ++ E + L QQ++ + Q+++ + E K+ + ++E E E+ Q+
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE-AEYAGQLAELRQR 593
E+ + E +R EE E+++ ++LE++M +K EK +E E + ++R++
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK------EEKIRELEEKMHEQEKIREQ 395
Query: 594 LDHAEADRQELQDELRQEREARQ-KLEMMIKELKLQILKSSK 634
+ + + + + E RQE+EA+ + E I+E + +I + K
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/167 (23%), Positives = 85/167 (50%), Gaps = 6/167 (3%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
++ I E++K + EE+ R K +E+ + QK++ + E K ++ EE+ +
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ--EEKMHD 506
Query: 533 QKELESLQNEHAQRMEEFYVEQKD-LEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELR 591
Q+E Q E R EE EQ++ + ++ E+I +Q+ EK E E + + +
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE---EKMQEQ 563
Query: 592 QRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
+++ E +E ++++R+++E ++ E I E + +I + + +E
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/173 (21%), Positives = 82/173 (47%), Gaps = 24/173 (13%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTE---------- 527
+++K + EE+ R K E+ + Q+++ + E KM + ++E E
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR 526
Query: 528 -------EQQNLQKELESLQNEHAQRM---EEFYVEQKDLEKKLEQIMKQKCTCDSNLEK 577
EQ+ +E E + E ++M EE EQ+ + ++ E+I +Q+ EK
Sbjct: 527 EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
Query: 578 DKEAEYAGQLAELRQRLDHAEADRQELQDEL--RQEREARQKLEMMIKELKLQ 628
+E E ++ E +++ E QE ++++ ++E+ Q+ +M +E K++
Sbjct: 587 IREQE--EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
Score = 40.8 bits (94), Expect = 0.004
Identities = 31/150 (20%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Query: 479 DDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELES 538
D + KI E+ + + +Q+EK+ +++++++ + + + + M + EE+ Q+E
Sbjct: 506 DQEEKIREQEEKMW-RQEEKIR---EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ 561
Query: 539 LQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAE 598
Q + ++ E+ +++ + ++ E+I +Q+ EK +E E Q E + +
Sbjct: 562 EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Query: 599 ADRQELQDELRQEREARQKLEMMIKELKLQ 628
QE + + ++E+ RQ+ +M +E++L+
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 651
Score = 40.4 bits (93), Expect = 0.005
Identities = 34/142 (23%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
E++ K QE+ I +++++++ + + + + M EE+ Q+E+ + E +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQ 605
R+EE E+++ ++LE+ M ++ EK +E E + E RQ A+ RQE +
Sbjct: 367 RLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQE-QEAKMWRQEEK 424
Query: 606 DELRQEREARQKLEMMIKELKL 627
++E+ Q+ +M +E K+
Sbjct: 425 IREQEEKIREQEKKMWRQEEKI 446
Score = 40.0 bits (92), Expect = 0.007
Identities = 37/173 (21%), Positives = 86/173 (49%), Gaps = 12/173 (6%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLN-----LILQKKQQLQMEVKMLSSSK-SMKELT 526
++ I E +K + E M +Q+EK+ + Q+K+ + E K+ K +E
Sbjct: 402 EEKIREQEKRQEQEAKM---WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458
Query: 527 EEQQNLQKELESL-QNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAG 585
+EQ+ + ++ E + + E R +E EQ+ + K+ E++ +Q+ EK +E E
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE--E 516
Query: 586 QLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
++ +++ E +E ++++R++ E Q+ E + E + ++ + K ++
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ 569
Score = 38.5 bits (88), Expect = 0.019
Identities = 39/195 (20%), Positives = 86/195 (44%), Gaps = 34/195 (17%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSM---KELTEEQQNLQK 534
+++K + E++ +Q+++ + Q+++ + E K+ K M +E EQ+ +++
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
Query: 535 ELESLQNEHAQRMEEFYVEQKDL-------------EKKLEQIMKQKCTCDSNLEKDKEA 581
E + + E R EE EQ+++ K+ E++ +Q+ EK +E
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ 514
Query: 582 E------------YAGQLAELRQRLDHAEADRQEL------QDELRQEREARQKLEMMIK 623
E ++ E +++ E QE Q+E QE+E ++ E I+
Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR 574
Query: 624 ELKLQILKSSKTAKE 638
E + +I + + +E
Sbjct: 575 EQEEKIREQKEKIRE 589
Score = 37.0 bits (84), Expect = 0.056
Identities = 34/161 (21%), Positives = 79/161 (49%), Gaps = 20/161 (12%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
+++K + EE +R +Q+EK+ Q++ + E KM + M E E+ + L+ E+
Sbjct: 319 QEEKIREQEEKIR---EQEEKMRR--QEEMMWEKEEKMRRQEEMMWEKEEKMRRLE-EMM 372
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ E + +EE EQ+ + ++ E+ +++ + +++EA+ Q ++R++ +
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 432
Query: 598 EADRQEL--------------QDELRQEREARQKLEMMIKE 624
+++ ++E RQE+E + E I+E
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/160 (19%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 486 EEVMRTYLKQQ-EKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA 544
+E +R L+ Q + ++ +K +LQM + Q+ K+LE +
Sbjct: 118 QEALRRELEAQVHTIRILTCQKTELQMALYY-------------SQHAVKQLEGEARDLI 164
Query: 545 QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLE---KDKEA-------------EYAGQLA 588
R+ + + +LE+ L + QK D +E K+++A E + A
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 224
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQ 628
+L+++L E+++ E+Q +++ + ++ ++++ + +LQ
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 264
Score = 31.2 bits (69), Expect = 3.1
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 10/112 (8%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTE---EQQNLQKELESLQNEHAQRM--- 547
K QE+ + Q+++ + E K+ + ++E E EQ+ +E E + E ++M
Sbjct: 559 KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618
Query: 548 EEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEA 599
EE EQ++ ++ E+ M+++ ++E Q ++++ +H EA
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQ----EEKMWEQEVRLRQQEEKMQEHQEHLEA 666
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/158 (24%), Positives = 75/158 (47%), Gaps = 5/158 (3%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNE--H 543
EE+ K QEKL L+ +K ++Q+ VK L +L QQ LQ E + L E
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 544 AQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE---AEYAGQLAELRQRLDHAEAD 600
+ VE+ +L +L Q ++K +++E E ++ E +++ E
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 601 RQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
E ++++R++ E + E I+EL+ ++ + K ++
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Score = 47.4 bits (111), Expect = 4e-05
Identities = 34/168 (20%), Positives = 88/168 (52%), Gaps = 5/168 (2%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
++ I E ++ + EE +R K+QE+ + +++++++ + + + + M + EE+
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415
Query: 533 QKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE--AEYAGQLAEL 590
Q+E Q E Q EE Q++ ++ E+ ++++ + + + +E E ++ E
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ---EEKIREQEEMMQEQEEKMGEQ 472
Query: 591 RQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
++ EA QE ++++R++ E ++ E I+E + +I + + +E
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/165 (24%), Positives = 88/165 (53%), Gaps = 11/165 (6%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTE---EQQNLQK 534
+++K + EE MR +QE++ ++K + Q E+ M + ++EL E EQ+ +++
Sbjct: 307 QEEKIREQEEKMR----RQEEMMWEKEEKMRRQEEM-MWEKEEKIRELEEKMHEQEKIRE 361
Query: 535 ELESLQNEHAQRMEEFYVEQK-DLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQR 593
+ E Q E R +E EQ+ + ++ E+I +Q+ E +E E ++ E ++
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE--EKMGEQEEK 419
Query: 594 LDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
+ E + QE ++++R++ E ++ E I+E + +I + + +E
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Score = 43.1 bits (100), Expect = 8e-04
Identities = 33/144 (22%), Positives = 76/144 (52%), Gaps = 5/144 (3%)
Query: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQ 540
+ ++ E + L QQ++ + Q+++ + E K+ + ++E EE+ Q+E+ +
Sbjct: 270 QAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE-QEEKMRRQEEMMWEK 328
Query: 541 NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD 600
E +R EE E+++ ++LE+ M ++ EK +E E ++ E +R + EA
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE---KIREQEKRQEQ-EAK 384
Query: 601 RQELQDELRQEREARQKLEMMIKE 624
++++R++ E ++ E M++E
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQE 408
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/152 (22%), Positives = 79/152 (51%), Gaps = 17/152 (11%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
++++ + EE MR +Q+EK+ Q+K+ + E K+ + +E+ +EQ+ E E
Sbjct: 423 QEEEMQEQEEKMR---RQEEKIRE--QEKKIREQEEKI----REQEEMMQEQEEKMGEQE 473
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ-----LAELRQ 592
E +M+E +++ + ++ E+I +Q+ EK +E E Q + E +
Sbjct: 474 GKMCEQEAKMQE---QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 530
Query: 593 RLDHAEADRQELQDELRQEREARQKLEMMIKE 624
++ E QE ++++R++ E ++ E+ +++
Sbjct: 531 KMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Score = 40.8 bits (94), Expect = 0.004
Identities = 27/143 (18%), Positives = 76/143 (53%), Gaps = 2/143 (1%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
E++ R K QE+ I +++++++ + + + + M EE+ Q+E+ + E +
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQ 605
+EE EQ+ + ++ E+ +++ + +++EA+ Q ++R++ + + +Q
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ 407
Query: 606 DELRQEREARQKLEMMIKELKLQ 628
++ +E+ Q+ +M +E ++Q
Sbjct: 408 EQ--EEKMGEQEEKMWEQEEEMQ 428
Score = 38.9 bits (89), Expect = 0.015
Identities = 41/164 (25%), Positives = 79/164 (48%), Gaps = 7/164 (4%)
Query: 479 DDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELES 538
D GK ++ V Q E+ L + QQ E KM + ++E E+ Q ++++
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQ--QEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Query: 539 LQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLE-KDKEAEYAGQLAELRQRLD-- 595
Q E +R EE E+++ ++ E++M +K LE K E E + E RQ +
Sbjct: 314 -QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 372
Query: 596 HAEADRQELQDEL-RQEREARQKLEMMIKELKLQILKSSKTAKE 638
+ RQE + ++ RQE + R++ E + ++ ++ + K ++
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Score = 38.9 bits (89), Expect = 0.015
Identities = 34/163 (20%), Positives = 81/163 (49%), Gaps = 9/163 (5%)
Query: 479 DDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELES 538
++K + EE +R +Q+EK+ Q++ + E KM + M E E+ + L++++
Sbjct: 301 EEKIQEQEEKIR---EQEEKMRR--QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355
Query: 539 LQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ---LAELRQRLD 595
Q + ++ E+ E+K E++ Q + K +++E + Q + E +++
Sbjct: 356 -QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 596 HAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
E E ++E++++ E ++ E I+E + +I + + +E
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Score = 35.0 bits (79), Expect = 0.21
Identities = 31/160 (19%), Positives = 75/160 (46%), Gaps = 30/160 (18%)
Query: 486 EEVMRTYLKQQ-EKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA 544
+E +R L+ Q + + ++ +K +LQM + Q+ K+LE +
Sbjct: 106 QEALRRELEAQVQTIRILTCQKTELQMALYY-------------SQHAVKQLEGEARDLI 152
Query: 545 QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLE---KDKEA-------------EYAGQLA 588
R+ + + +LE+ L + QK D +E K+++A E + A
Sbjct: 153 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 212
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQ 628
+L+++L E+++ E+Q +++ + ++ ++++ + +LQ
Sbjct: 213 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 252
Score = 30.0 bits (66), Expect = 6.8
Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 476 ICEDD-KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQK 534
+CE + K + EE MR +Q+EK+ Q+K+ + E K+ + M+E EE+ Q+
Sbjct: 476 MCEQEAKMQEQEEKMR---RQEEKIRE--QEKKIREQEEKIREQEEMMQE-QEEKMWEQE 529
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQK 568
E Q E Q EE Q++ ++ E ++Q+
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/172 (24%), Positives = 89/172 (51%), Gaps = 18/172 (10%)
Query: 478 EDDKGKIMEEVMRTYLKQ---QEKLNLILQ--KKQQLQMEVKMLSSSKSMKELTEEQQNL 532
E + G ++ + LK+ KLN L+ + ++ Q+ +++ K+ +ELTE +NL
Sbjct: 298 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 357
Query: 533 QKELESLQNEHA------QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ 586
Q E SLQ+E+ Q++++ +L ++ E + +K T + N +KE +
Sbjct: 358 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEE----K 413
Query: 587 LAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
L+++ +++ HA +EL+ ++ ++ ++LE I + QI+ K A +
Sbjct: 414 LSKVDEKISHA---TEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 462
Score = 35.8 bits (81), Expect = 0.12
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Query: 525 LTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYA 584
L EE+ L ++ +Q E+ E ++ EK+ + + TC+ + E E
Sbjct: 85 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE-- 142
Query: 585 GQLAELRQRLDHAEADRQELQDELRQEREAR-QKLEMMIKELKLQILKSSKTAK 637
++ L + L ++ E QDEL + R Q LE K LK Q+ ++ T K
Sbjct: 143 DEILCLEKELKEEKSKHSE-QDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 195
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/124 (22%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 507 QQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMK 566
Q L+ + L+ S S EL +E L+KEL+ +++H+++ E D+ K+++ +
Sbjct: 125 QSLEATCEKLNRSNS--ELEDEILCLEKELKEEKSKHSEQDE----LMADISKRIQSLED 178
Query: 567 QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEA--DRQELQDELRQEREARQKLEMMIKE 624
+ + S + + K Q+ E R ++ +A + +LQ+ +Q + + + + E
Sbjct: 179 ESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSE 238
Query: 625 LKLQ 628
L Q
Sbjct: 239 LNKQ 242
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/172 (24%), Positives = 89/172 (51%), Gaps = 18/172 (10%)
Query: 478 EDDKGKIMEEVMRTYLKQ---QEKLNLILQ--KKQQLQMEVKMLSSSKSMKELTEEQQNL 532
E + G ++ + LK+ KLN L+ + ++ Q+ +++ K+ +ELTE +NL
Sbjct: 298 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 357
Query: 533 QKELESLQNEHA------QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ 586
Q E SLQ+E+ Q++++ +L ++ E + +K T + N +KE +
Sbjct: 358 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEE----K 413
Query: 587 LAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
L+++ +++ HA +EL+ ++ ++ ++LE I + QI+ K A +
Sbjct: 414 LSKVDEKISHA---TEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 462
Score = 35.8 bits (81), Expect = 0.12
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Query: 525 LTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYA 584
L EE+ L ++ +Q E+ E ++ EK+ + + TC+ + E E
Sbjct: 85 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE-- 142
Query: 585 GQLAELRQRLDHAEADRQELQDELRQEREAR-QKLEMMIKELKLQILKSSKTAK 637
++ L + L ++ E QDEL + R Q LE K LK Q+ ++ T K
Sbjct: 143 DEILCLEKELKEEKSKHSE-QDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 195
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/124 (22%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 507 QQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMK 566
Q L+ + L+ S S EL +E L+KEL+ +++H+++ E D+ K+++ +
Sbjct: 125 QSLEATCEKLNRSNS--ELEDEILCLEKELKEEKSKHSEQDE----LMADISKRIQSLED 178
Query: 567 QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEA--DRQELQDELRQEREARQKLEMMIKE 624
+ + S + + K Q+ E R ++ +A + +LQ+ +Q + + + + E
Sbjct: 179 ESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSE 238
Query: 625 LKLQ 628
L Q
Sbjct: 239 LNKQ 242
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/172 (24%), Positives = 89/172 (51%), Gaps = 18/172 (10%)
Query: 478 EDDKGKIMEEVMRTYLKQ---QEKLNLILQ--KKQQLQMEVKMLSSSKSMKELTEEQQNL 532
E + G ++ + LK+ KLN L+ + ++ Q+ +++ K+ +ELTE +NL
Sbjct: 269 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 328
Query: 533 QKELESLQNEHA------QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ 586
Q E SLQ+E+ Q++++ +L ++ E + +K T + N +KE +
Sbjct: 329 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEE----K 384
Query: 587 LAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
L+++ +++ HA +EL+ ++ ++ ++LE I + QI+ K A +
Sbjct: 385 LSKVDEKISHA---TEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 433
Score = 35.8 bits (81), Expect = 0.12
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Query: 525 LTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYA 584
L EE+ L ++ +Q E+ E ++ EK+ + + TC+ + E E
Sbjct: 56 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE-- 113
Query: 585 GQLAELRQRLDHAEADRQELQDELRQEREAR-QKLEMMIKELKLQILKSSKTAK 637
++ L + L ++ E QDEL + R Q LE K LK Q+ ++ T K
Sbjct: 114 DEILCLEKELKEEKSKHSE-QDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 166
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/124 (22%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 507 QQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMK 566
Q L+ + L+ S S EL +E L+KEL+ +++H+++ E D+ K+++ +
Sbjct: 96 QSLEATCEKLNRSNS--ELEDEILCLEKELKEEKSKHSEQDE----LMADISKRIQSLED 149
Query: 567 QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEA--DRQELQDELRQEREARQKLEMMIKE 624
+ + S + + K Q+ E R ++ +A + +LQ+ +Q + + + + E
Sbjct: 150 ESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSE 209
Query: 625 LKLQ 628
L Q
Sbjct: 210 LNKQ 213
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/172 (24%), Positives = 89/172 (51%), Gaps = 18/172 (10%)
Query: 478 EDDKGKIMEEVMRTYLKQ---QEKLNLILQ--KKQQLQMEVKMLSSSKSMKELTEEQQNL 532
E + G ++ + LK+ KLN L+ + ++ Q+ +++ K+ +ELTE +NL
Sbjct: 286 ESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 345
Query: 533 QKELESLQNEHA------QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQ 586
Q E SLQ+E+ Q++++ +L ++ E + +K T + N +KE +
Sbjct: 346 QTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEE----K 401
Query: 587 LAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
L+++ +++ HA +EL+ ++ ++ ++LE I + QI+ K A +
Sbjct: 402 LSKVDEKISHA---TEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHD 450
Score = 35.8 bits (81), Expect = 0.12
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Query: 525 LTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYA 584
L EE+ L ++ +Q E+ E ++ EK+ + + TC+ + E E
Sbjct: 73 LIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE-- 130
Query: 585 GQLAELRQRLDHAEADRQELQDELRQEREAR-QKLEMMIKELKLQILKSSKTAK 637
++ L + L ++ E QDEL + R Q LE K LK Q+ ++ T K
Sbjct: 131 DEILCLEKELKEEKSKHSE-QDELMADISKRIQSLEDESKSLKSQVAEAKMTFK 183
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/124 (22%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 507 QQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMK 566
Q L+ + L+ S S EL +E L+KEL+ +++H+++ E D+ K+++ +
Sbjct: 113 QSLEATCEKLNRSNS--ELEDEILCLEKELKEEKSKHSEQDE----LMADISKRIQSLED 166
Query: 567 QKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEA--DRQELQDELRQEREARQKLEMMIKE 624
+ + S + + K Q+ E R ++ +A + +LQ+ +Q + + + + E
Sbjct: 167 ESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSE 226
Query: 625 LKLQ 628
L Q
Sbjct: 227 LNKQ 230
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 52.0 bits (123), Expect = 2e-06
Identities = 39/156 (25%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNE--H 543
EE+ K QEKL L+ +K ++Q+ VK L +L QQ LQ E + L E
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 544 AQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQE 603
+ VE+ +L +L Q ++K +++K E+ ++ E +++ E +E
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMW----RQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 604 LQDELRQEREAR-QKLEMMIKELKLQILKSSKTAKE 638
++++R++ E +K E M ++ ++ K K ++
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
Score = 43.9 bits (102), Expect = 5e-04
Identities = 34/153 (22%), Positives = 81/153 (52%), Gaps = 11/153 (7%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSM---KELTEEQQNLQK 534
+++K + E++ +Q+++ + Q+++ + E K+ K M +E EQ+ +++
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRL 594
E + + E R EE EQ+++ ++ E++ +Q + + K +E + Q ++R++
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ----EEKIRKQEEKVWR-QEEKIREQ- 522
Query: 595 DHAEADRQELQDELRQEREARQKLEMMIKELKL 627
E R++ + RQE + R++ EM +E K+
Sbjct: 523 --EEKIREQEEKMWRQEEKIREQEEMWREEEKM 553
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/151 (22%), Positives = 79/151 (52%), Gaps = 8/151 (5%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
E++ K QE+ I +++++++ + + + + M EE+ Q+E+ + E +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE-AEYAGQLAELRQRLDHAEADRQEL 604
R EE E+++ ++ E++M +K EK +E E + ++R++ + + + +
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEK------EEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
Query: 605 QDELRQEREARQ-KLEMMIKELKLQILKSSK 634
+ E RQE+EA+ + E I+E + +I + K
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/162 (22%), Positives = 82/162 (50%), Gaps = 5/162 (3%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
+++K + EE+ R K E+ + ++K+Q Q E KM + ++E E+ ++++
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ-EDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ + ++ E+ + +++ + ++ E+I +Q+ EK +E E Q E +++
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ--EQEEKMGEQ 652
Query: 598 EADRQELQDELRQEREARQ-KLEMMIKELKLQILKSSKTAKE 638
E E Q+E QE+E + E I+E + +I + + +E
Sbjct: 653 EEKMCE-QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693
Score = 40.8 bits (94), Expect = 0.004
Identities = 41/150 (27%), Positives = 77/150 (51%), Gaps = 8/150 (5%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
+++K + EE +R +Q+EK+ Q++ + E KM + M E EE+ Q+E+
Sbjct: 319 QEEKIREQEEKIR---EQEEKMRR--QEEMMWEKEEKMRRQEEMMWE-KEEKMRRQEEMM 372
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ E +R EE E+++ ++LE+ M ++ EK +E E + E RQ A
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQE-QEA 430
Query: 598 EADRQELQDELRQEREARQKLEMMIKELKL 627
+ RQE + ++E+ Q+ +M +E K+
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Score = 40.0 bits (92), Expect = 0.007
Identities = 35/169 (20%), Positives = 88/169 (52%), Gaps = 13/169 (7%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSM----KELTEE 528
++ I E++K + EE+ R K E+ + QK++ + E K+ + + +++ E+
Sbjct: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ 522
Query: 529 QQNLQKELESL--QNEHAQRMEEFYVEQKDL---EKKLEQIMKQKCTCDSNLEKDKEAEY 583
++ ++++ E + Q E + EE + E++ + EK E+ +Q+ +++K E
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 584 AGQLAELRQRLDHAEADRQELQDEL-RQE---REARQKLEMMIKELKLQ 628
++ +++ E RQE ++++ +QE RE +K++ ++++ Q
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Score = 39.7 bits (91), Expect = 0.009
Identities = 30/153 (19%), Positives = 79/153 (51%), Gaps = 12/153 (7%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLN----LILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQ 533
+++K + EE M KQ+EK+ I +++++++ + + + + M + EE+ Q
Sbjct: 596 QEEKRQEQEEKM---WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 534 KELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE--AEYAGQLAELR 591
+E Q E Q EE Q++ ++ E+ ++++ + + + +E E ++ E
Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ---EEKIREQEEMMQEQEEKMWEQE 709
Query: 592 QRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
+++ E QE ++++R++ E + E+ +++
Sbjct: 710 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Score = 36.2 bits (82), Expect = 0.095
Identities = 34/161 (21%), Positives = 78/161 (48%), Gaps = 20/161 (12%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
+++K + EE+M +++EK+ Q++ + E KM + M E EE+ Q+E+
Sbjct: 333 QEEKMRRQEEMM---WEKEEKMRR--QEEMMWEKEEKMRRQEEMMWE-KEEKMRRQEEMM 386
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ E + +EE EQ+ + ++ E+ +++ + +++EA+ Q ++R++ +
Sbjct: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Query: 598 EADRQEL--------------QDELRQEREARQKLEMMIKE 624
+++ ++E RQE+E + E I E
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Score = 35.8 bits (81), Expect = 0.12
Identities = 27/145 (18%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
E++ K+QE+ + +++++++ + + + + EE+ Q+E+ Q E
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQ 605
EE EQ++ ++ E+ M + +++K E ++ E +++ E QE +
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWR--------QEEKIREQEKKIREQEEKIREQEEMMQEQE 702
Query: 606 DEL--RQEREARQKLEMMIKELKLQ 628
+++ ++E+ Q+ +M +E K++
Sbjct: 703 EKMWEQEEKMCEQEEKMQEQEEKMR 727
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/160 (19%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 486 EEVMRTYLKQQ-EKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA 544
+E +R L+ Q + ++ +K +LQM + Q+ K+LE +
Sbjct: 118 QEALRRELEAQVHTIRILTCQKTELQMALYY-------------SQHAVKQLEGEARDLI 164
Query: 545 QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLE---KDKEA-------------EYAGQLA 588
R+ + + +LE+ L + QK D +E K+++A E + A
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 224
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQ 628
+L+++L E+++ E+Q +++ + ++ ++++ + +LQ
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 264
Score = 31.6 bits (70), Expect = 2.3
Identities = 23/99 (23%), Positives = 52/99 (52%), Gaps = 6/99 (6%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLN----LILQKKQQLQMEVKMLSSSKSMKELTEE 528
++ +CE ++ M+E T +Q+EK+ I +++++++ + +M+ + EE
Sbjct: 653 EEKMCEQEEK--MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 529 QQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQ 567
+ Q+E Q E +R EE EQ+ ++ E+ M++
Sbjct: 711 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 52.0 bits (123), Expect = 2e-06
Identities = 39/156 (25%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNE--H 543
EE+ K QEKL L+ +K ++Q+ VK L +L QQ LQ E + L E
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 544 AQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQE 603
+ VE+ +L +L Q ++K +++K E+ ++ E +++ E +E
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMW----RQEEKIQEWEEKIQEQEEKIREQEEKIRE 393
Query: 604 LQDELRQEREAR-QKLEMMIKELKLQILKSSKTAKE 638
++++R++ E +K E M ++ ++ K K ++
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 429
Score = 46.6 bits (109), Expect = 7e-05
Identities = 37/166 (22%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 473 KDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNL 532
++ I E++K + EE+ R K +E+ + QK++ + E K+ + M EE+ +
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWR-QEEKMHD 568
Query: 533 QKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQ 592
Q+E Q E R EE EQ++ ++ E+ +++ +++ E ++ E +
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE--------QEEMTQEQEEKMGEQEE 620
Query: 593 RLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
++ E QE ++++R++ E ++ E I+E + +I + + +E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/155 (20%), Positives = 80/155 (51%), Gaps = 8/155 (5%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSM---KELTEEQQNLQK 534
+++K + E++ +Q+++ + Q+++ + E K+ + M +E EQ+ +++
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEK-----DKEAEYAGQLAE 589
E + + E R EE EQ+++ ++ E+I +Q+ EK +K + ++ E
Sbjct: 516 EEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE 575
Query: 590 LRQRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
+++ E +E ++++R++ E ++ E M +E
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610
Score = 43.1 bits (100), Expect = 8e-04
Identities = 34/150 (22%), Positives = 78/150 (52%), Gaps = 10/150 (6%)
Query: 479 DDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELES 538
D + KI E+ + + +Q+EK+ +K ++ + +++ +E+T+EQ+ E E
Sbjct: 568 DQEEKIREQEEKVW-RQEEKIREQEEKIREQEEKIR------EQEEMTQEQEEKMGEQEE 620
Query: 539 LQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAE 598
E ++M+E +++ + ++ E+I +Q+ EK +E E Q E + +
Sbjct: 621 KMCEQEEKMQE---QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Query: 599 ADRQELQDELRQEREARQKLEMMIKELKLQ 628
QE + + ++E+ RQ+ +M +E++L+
Sbjct: 678 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/160 (21%), Positives = 84/160 (52%), Gaps = 15/160 (9%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
+++K + EE +R +Q+EK+ Q++ + E KM + M E EE+ Q+E+
Sbjct: 380 QEEKIREQEEKIR---EQEEKMR--RQEEMMWEKEEKMRRQEEMMWE-KEEKMRRQEEMM 433
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ E + +EE EQ+ + ++ E+ +++ + +++EA+ Q ++R++ +
Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 598 EADRQEL---------QDELRQEREARQKLEMMIKELKLQ 628
+++ Q+++R+E + +++ EM +E K++
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 533
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/170 (24%), Positives = 85/170 (50%), Gaps = 13/170 (7%)
Query: 479 DDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKE----LTEEQQNLQK 534
++K E++ K+QE+ + Q+K+Q Q E KM + ++E + E+++ + +
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ-EAKMWRQEEKIREQEEKIREQEEKMWR 502
Query: 535 ELESLQNEHAQRMEEFYVEQKDL---EKKL---EQIMKQKCTCDSNLEKDKEAEYAGQLA 588
+ E + + R EE EQ+++ E+K+ E+I +QK EK ++ E
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
E + D E R++ + RQE + R++ E I+E + +I + + +E
Sbjct: 563 EEKMH-DQEEKIREQEEKVWRQEEKIREQ-EEKIREQEEKIREQEEMTQE 610
Score = 40.0 bits (92), Expect = 0.007
Identities = 34/154 (22%), Positives = 75/154 (48%), Gaps = 15/154 (9%)
Query: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTE------EQQNLQK 534
+ ++ E + L QQ++ + Q+++ + E K+ + ++E E E+ Q+
Sbjct: 343 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 402
Query: 535 ELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRL 594
E+ + E +R EE E+++ ++ E++M +K EK +E E + ++++
Sbjct: 403 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK------EEKIRELE---EKMHEQEKI 453
Query: 595 DHAEADRQELQDELRQEREARQKLEMMIKELKLQ 628
E RQE + QE+ Q+ +M +E K++
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487
Score = 39.3 bits (90), Expect = 0.011
Identities = 32/140 (22%), Positives = 73/140 (52%), Gaps = 5/140 (3%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQ 545
E++ K QE+ I +++++++ + + + + M EE+ Q+E+ + E +
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 546 RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQ 605
R EE E+++ ++LE+ M ++ EK +E E ++ E +R + EA +
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE---KIREQEKRQEQ-EAKMWRQE 483
Query: 606 DELR-QEREARQKLEMMIKE 624
+++R QE + R++ E M ++
Sbjct: 484 EKIREQEEKIREQEEKMWRQ 503
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/160 (19%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 486 EEVMRTYLKQQ-EKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA 544
+E +R L+ Q + ++ +K +LQM + Q+ K+LE +
Sbjct: 179 QEALRRELEAQVHTIRILTCQKTELQMALYY-------------SQHAVKQLEGEARDLI 225
Query: 545 QRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLE---KDKEA-------------EYAGQLA 588
R+ + + +LE+ L + QK D +E K+++A E + A
Sbjct: 226 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 285
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQ 628
+L+++L E+++ E+Q +++ + ++ ++++ + +LQ
Sbjct: 286 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 325
Score = 30.8 bits (68), Expect = 4.0
Identities = 25/99 (25%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 473 KDVICE-DDKGKIMEEVMRTY---LKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEE 528
++ +CE ++K + EE MR +++QEK I +++++++ + +M+ + EE
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKIREQEKK--IREQEEKIREQEEMMQEQEEKMWEQEE 676
Query: 529 QQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQ 567
+ Q+E Q E +R EE EQ+ ++ E+ M++
Sbjct: 677 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 52.0 bits (123), Expect = 2e-06
Identities = 70/320 (21%), Positives = 130/320 (40%), Gaps = 46/320 (14%)
Query: 340 EEKKLKIILEEMKEKFSMRSGKRNQSKTDAP--------SGMELQSWYPVIKQEGDHVSQ 391
E +KLK LEE K++ + + + Q K +A + +LQ + KQ+ D + +
Sbjct: 319 EVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQE 378
Query: 392 THSFLHP-SYYLYMCDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCN 450
L M +K N +S L +EA + N+ KR+ +
Sbjct: 379 LQRELQMLQKESSMAEKEQTSNRKRVEELS----LELSEALRKLENSDKEKRQLQKTVAE 434
Query: 451 LVRDINKVGIGLVAAASSPLLVKDVICED--DKGKIMEEVMRTYLKQQEKLNLILQKKQQ 508
+N + + +K + ED + K++E+ K +E L+ + +
Sbjct: 435 QDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEA 494
Query: 509 LQMEVKMLSSSKSMKE----LTEEQQNLQKELESLQNEHAQRMEEFYVEQK---DLEKKL 561
L+ E K K++KE L EE +NL+ EL+ + + ++ Q+ DL K++
Sbjct: 495 LRQEFK--KKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEI 552
Query: 562 ----EQIMKQKCTCDSNLEKD------------------KEAEYAGQLAELRQRLDHAEA 599
E +M + D L+K+ K A L + ++L+H +
Sbjct: 553 ALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTS 612
Query: 600 DRQELQDELRQEREARQKLE 619
+ + LQ L Q +E + +LE
Sbjct: 613 ETKSLQQSLTQTQEKKAQLE 632
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/184 (23%), Positives = 89/184 (48%), Gaps = 14/184 (7%)
Query: 450 NLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQL 509
NLV+D+ +V + V+ ++ + E D + EE ++ + + ++ + Q+L
Sbjct: 182 NLVKDL-RVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQEL 240
Query: 510 QMEVK-----MLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQI 564
Q+E L K ++E E Q L+K+L +QN ++ +E +Q+ + +LE
Sbjct: 241 QLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKEL-EKQQCMATELEMT 299
Query: 565 MKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
+K ++ +K KEAE AE+++ + E +Q Q+ L ++ A+ K E +
Sbjct: 300 VK-----EAKQDKSKEAECKALQAEVQKLKNSLEEAKQ--QERLAAQQAAQCKEEAALAG 352
Query: 625 LKLQ 628
L+
Sbjct: 353 CHLE 356
Score = 33.1 bits (74), Expect = 0.80
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 28/138 (20%)
Query: 521 SMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDK- 579
S E E+ + + K L+ ++ +EE+ KDL +LE + +QK N+ KD
Sbjct: 151 SSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQK----RNIMKDMM 206
Query: 580 --EAEYAGQLAELRQRLDHAEAD-------RQELQDE--------------LRQEREARQ 616
E + G E ++ + D QELQ E L+++ E Q
Sbjct: 207 KLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQ 266
Query: 617 KLEMMIKELKLQILKSSK 634
+LE + +++ +LK K
Sbjct: 267 ELEKKLTQVQNSLLKKEK 284
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 52.0 bits (123), Expect = 2e-06
Identities = 70/320 (21%), Positives = 130/320 (40%), Gaps = 46/320 (14%)
Query: 340 EEKKLKIILEEMKEKFSMRSGKRNQSKTDAP--------SGMELQSWYPVIKQEGDHVSQ 391
E +KLK LEE K++ + + + Q K +A + +LQ + KQ+ D + +
Sbjct: 464 EVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQE 523
Query: 392 THSFLHP-SYYLYMCDKVVAPNVSLTSAVSQSKELTKTEANASISNNSTSKRKSESATCN 450
L M +K N +S L +EA + N+ KR+ +
Sbjct: 524 LQRELQMLQKESSMAEKEQTSNRKRVEELS----LELSEALRKLENSDKEKRQLQKTVAE 579
Query: 451 LVRDINKVGIGLVAAASSPLLVKDVICED--DKGKIMEEVMRTYLKQQEKLNLILQKKQQ 508
+N + + +K + ED + K++E+ K +E L+ + +
Sbjct: 580 QDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEA 639
Query: 509 LQMEVKMLSSSKSMKE----LTEEQQNLQKELESLQNEHAQRMEEFYVEQK---DLEKKL 561
L+ E K K++KE L EE +NL+ EL+ + + ++ Q+ DL K++
Sbjct: 640 LRQEFK--KKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEI 697
Query: 562 ----EQIMKQKCTCDSNLEKD------------------KEAEYAGQLAELRQRLDHAEA 599
E +M + D L+K+ K A L + ++L+H +
Sbjct: 698 ALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTS 757
Query: 600 DRQELQDELRQEREARQKLE 619
+ + LQ L Q +E + +LE
Sbjct: 758 ETKSLQQSLTQTQEKKAQLE 777
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/184 (23%), Positives = 89/184 (48%), Gaps = 14/184 (7%)
Query: 450 NLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQL 509
NLV+D+ +V + V+ ++ + E D + EE ++ + + ++ + Q+L
Sbjct: 327 NLVKDL-RVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQEL 385
Query: 510 QMEVK-----MLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQI 564
Q+E L K ++E E Q L+K+L +QN ++ +E +Q+ + +LE
Sbjct: 386 QLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKEL-EKQQCMATELEMT 444
Query: 565 MKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKE 624
+K ++ +K KEAE AE+++ + E +Q Q+ L ++ A+ K E +
Sbjct: 445 VK-----EAKQDKSKEAECKALQAEVQKLKNSLEEAKQ--QERLAAQQAAQCKEEAALAG 497
Query: 625 LKLQ 628
L+
Sbjct: 498 CHLE 501
Score = 33.1 bits (74), Expect = 0.80
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 28/138 (20%)
Query: 521 SMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDK- 579
S E E+ + + K L+ ++ +EE+ KDL +LE + +QK N+ KD
Sbjct: 296 SSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQK----RNIMKDMM 351
Query: 580 --EAEYAGQLAELRQRLDHAEAD-------RQELQDE--------------LRQEREARQ 616
E + G E ++ + D QELQ E L+++ E Q
Sbjct: 352 KLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQ 411
Query: 617 KLEMMIKELKLQILKSSK 634
+LE + +++ +LK K
Sbjct: 412 ELEKKLTQVQNSLLKKEK 429
Score = 30.8 bits (68), Expect = 4.0
Identities = 32/159 (20%), Positives = 67/159 (42%), Gaps = 15/159 (9%)
Query: 494 KQQEKLNLILQKKQQLQMEVKMLSS-SKSMKELTEEQQNLQKELESLQNEHAQRME---- 548
K +E +LQ ++Q Q ++KML++ + ++E EE L++ L E +
Sbjct: 814 KLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWSVP 873
Query: 549 ----EFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE------AEYAGQLAELRQRLDHAE 598
Y + LEQ KQ+ + L A+ +G+ L + H +
Sbjct: 874 KDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLHSVMVHLQ 933
Query: 599 ADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAK 637
+ ++L+ E+ +++ + + K L +S++ K
Sbjct: 934 QENKKLKKEIEEKKMKAENTRLCTKALGPSRTESTQREK 972
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/249 (23%), Positives = 107/249 (42%), Gaps = 27/249 (10%)
Query: 390 SQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQ--SKELTKTEANASISNNSTSKRKSESA 447
S ++FL S M D + P + Q + + E ++ N + ++
Sbjct: 191 SSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQ 250
Query: 448 TCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQ 507
+ + I+++ + A+SPL K++ DK + + + LKQ + L +K
Sbjct: 251 IAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKT---EKS 307
Query: 508 QLQMEVKMLSS-----SKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLE 562
Q+ ++ LS S ++E Q LQ L L EH++ +E+ +Q LEK+L
Sbjct: 308 QMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELS 367
Query: 563 QIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMI 622
++ D ++K G+L++L + L +LQD QE K E++
Sbjct: 368 AALQ-----DKKCLEEKNEILQGKLSQLEEHL-------SQLQDNPPQE-----KGEVLG 410
Query: 623 KELKLQILK 631
L+L+ LK
Sbjct: 411 DVLQLETLK 419
Score = 49.7 bits (117), Expect = 8e-06
Identities = 53/227 (23%), Positives = 106/227 (46%), Gaps = 22/227 (9%)
Query: 428 TEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEE 487
T+ +SISN S +K + E A+ + VA+ +S L + + ++
Sbjct: 469 TDLQSSISNLSQAKEELEQASQAHGARLT----AQVASLTSELTTLNATIQQQDQELAGL 524
Query: 488 VMRTYLKQQEKLNLILQKKQQ---LQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHA 544
+ KQ + + Q++Q L+ +V+ LSSS KE ++ + + ++ E+ + +HA
Sbjct: 525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKE--QQLKEVAEKQEATRQDHA 582
Query: 545 QRM------EEFYVEQKDLE-KKLEQIMKQKCT----CDSNLEKDKEAEYAGQLAELRQR 593
Q++ E + ++D K+LE + K+K L+ EA + Q + + +
Sbjct: 583 QQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQ 642
Query: 594 LDHAEADR--QELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE 638
+ AE R +ELQ + R+ + + + + EL+LQ+ + A E
Sbjct: 643 REKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATE 689
Score = 39.7 bits (91), Expect = 0.009
Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 37/175 (21%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEE--------- 528
E K K++EE R Q+E+ L Q +Q +EV +K ++EL+++
Sbjct: 1513 EGAKVKVLEERQRF---QEERQKLTAQVEQ---LEVFQREQTKQVEELSKKLADSDQASK 1566
Query: 529 -QQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAE-YAGQ 586
QQ K +++ E Q + + +L+ +L Q K++ AE Y Q
Sbjct: 1567 VQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQ-------------KEQAAEHYKLQ 1613
Query: 587 LAELRQRLDHAEADRQELQDELR-------QEREARQKLEMMIKELKLQILKSSK 634
+ + + D + QELQ++LR + +E R + E + EL+ LK+ +
Sbjct: 1614 MEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKE 1668
Score = 38.1 bits (87), Expect = 0.025
Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 39/177 (22%)
Query: 496 QEKLNLILQKKQQLQMEVKML-----SSSKSMKELTEEQQNLQKELESLQNEHAQ----- 545
QE L L +K+ E+ L + K ++EL + + L+++L + EHA
Sbjct: 1049 QEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQ 1108
Query: 546 ------------RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYA--------- 584
++E E LE +Q KQ+ DS LE+ EAE A
Sbjct: 1109 SEAAGRTEPTGPKLEALRAEVSKLE---QQCQKQQEQADS-LERSLEAERASRAERDSAL 1164
Query: 585 ----GQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAK 637
GQL E Q L H+++ Q EL R Q E K Q+ + + A+
Sbjct: 1165 ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAE 1221
Score = 35.4 bits (80), Expect = 0.16
Identities = 34/165 (20%), Positives = 74/165 (44%), Gaps = 24/165 (14%)
Query: 474 DVICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSK--SMKELTEEQQN 531
+V + + K ++E+ + +L + ++ Q E++++++ + ++ EE+Q
Sbjct: 1466 EVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQR 1525
Query: 532 LQKE----------LESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEA 581
Q+E LE Q E +++EE L KKL + S +++ K
Sbjct: 1526 FQEERQKLTAQVEQLEVFQREQTKQVEE-------LSKKLADSDQA-----SKVQQQKLK 1573
Query: 582 EYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELK 626
Q E +Q +A ELQ +L Q+ +A + ++ +++ K
Sbjct: 1574 AVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAK 1618
Score = 33.9 bits (76), Expect = 0.47
Identities = 34/142 (23%), Positives = 71/142 (50%), Gaps = 14/142 (9%)
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE----SLQNEHAQRMEEF 550
Q +L L L+ +QQ E + ++ K +L E+ Q L++ L+ SL+ E + +
Sbjct: 672 QVAELELQLRSEQQKATEKERVAQEKD--QLQEQLQALKESLKVTKGSLEEEKRRAADAL 729
Query: 551 YVEQK---DLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD----RQE 603
+Q+ +L+ + +++Q LE+++ A G A L+Q + +A+ R+E
Sbjct: 730 EEQQRCISELKAETRSLVEQHKRERKELEEER-AGRKGLEARLQQLGEAHQAETEVLRRE 788
Query: 604 LQDELRQEREARQKLEMMIKEL 625
L + + + A + E ++KE+
Sbjct: 789 LAEAMAAQHTAESECEQLVKEV 810
Score = 32.7 bits (73), Expect = 1.1
Identities = 32/138 (23%), Positives = 69/138 (50%), Gaps = 12/138 (8%)
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 554
Q+EK L +K ++LQ V+ ++ + E + L+ +L S Q + ++ E E+
Sbjct: 642 QREKAELS-RKVEELQACVE--TARQEQHEAQAQVAELELQLRSEQQKATEK-ERVAQEK 697
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDE------- 607
L+++L+ + + +LE++K A L E ++ + +A+ + L ++
Sbjct: 698 DQLQEQLQALKESLKVTKGSLEEEKRRA-ADALEEQQRCISELKAETRSLVEQHKRERKE 756
Query: 608 LRQEREARQKLEMMIKEL 625
L +ER R+ LE +++L
Sbjct: 757 LEEERAGRKGLEARLQQL 774
Score = 32.3 bits (72), Expect = 1.4
Identities = 22/109 (20%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
Query: 529 QQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLA 588
+Q L+ EL+ + ++ Q E + D E +L ++ ++ + LE A+Y G
Sbjct: 1462 RQFLEVELDQAREKYVQ---ELAAVRADAETRLAEVQREAQSTARELEV-MTAKYEGAKV 1517
Query: 589 ELRQRLDHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSKTAK 637
++ + + +RQ+L ++ Q +++ ++EL ++ S + +K
Sbjct: 1518 KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASK 1566
Score = 32.0 bits (71), Expect = 1.8
Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 8/194 (4%)
Query: 421 QSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAA-ASSPLLVKDVICED 479
Q + E A ++ + S +L +++ + ++ S L + V+ E
Sbjct: 1200 QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 1259
Query: 480 DKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESL 539
+K + +EE +R L Q E + + + + +S++E E+Q+ + L
Sbjct: 1260 EKSQKLEERLR--LLQAETAS---NSARAAERSSALREEVQSLREEAEKQRVASENLRQE 1314
Query: 540 QNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEA 599
A+R EE E K ++K Q K++ LE +L + +A
Sbjct: 1315 LTSQAERAEELGQELKAWQEKFFQ--KEQALSTLQLEHTSTQALVSELLPAKHLCQQLQA 1372
Query: 600 DRQELQDELRQERE 613
++ + R+E E
Sbjct: 1373 EQAAAEKRHREELE 1386
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/140 (28%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 496 QEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQ-----NLQKELESLQNEHAQRMEEF 550
Q+KL + + K++ E + K + L E+QQ QKE E + + + E+
Sbjct: 356 QKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQE 415
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKE-AEYAGQLAELRQRLDHAEADRQELQDELR 609
+ +Q +LEK+LE+ + + + KD E E A Q E ++RL+ RQEL ++
Sbjct: 416 WKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKN 475
Query: 610 QEREARQKLEMMIKELKLQI 629
+E+E +L K L L++
Sbjct: 476 REQEEIVRLNSKKKNLHLEL 495
Score = 32.3 bits (72), Expect = 1.4
Identities = 26/140 (18%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSS-----SKSMKELTEEQQNLQKELESLQ 540
+E++ ++QE++ + KK+ L +E++ L+ S ++++ ++Q + ELE L
Sbjct: 468 QELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLD 527
Query: 541 NE---HAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ +++ E ++ + KL ++ +K + E+ K +++ L
Sbjct: 528 KQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLN---ERIKNMQFSNTPDSGVSLLHKK 584
Query: 598 EADRQELQDELRQEREARQK 617
+++EL L+++ +A +K
Sbjct: 585 SLEKEELCQRLKEQLDALEK 604
Score = 30.4 bits (67), Expect = 5.2
Identities = 35/144 (24%), Positives = 70/144 (48%), Gaps = 23/144 (15%)
Query: 494 KQQEKLNLIL---QKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEF 550
KQ + +N L QK Q+ + + K+ + + ++ E+ N++ L+ ME+
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKANYERGNME-----LEKRRQALMEQ- 388
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQ 610
+Q++ E+K + K+K + + +E E+ QL EL +RL E Q EL +
Sbjct: 389 --QQREAERKAQ---KEKEEWERKQRELQEQEWKKQL-ELEKRL--------EKQRELER 434
Query: 611 EREARQKLEMMIKELKLQILKSSK 634
+RE ++ ++ +E Q L+ +
Sbjct: 435 QREEERRKDIERREAAKQELERQR 458
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/140 (28%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 496 QEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQ-----NLQKELESLQNEHAQRMEEF 550
Q+KL + + K++ E + K + L E+QQ QKE E + + + E+
Sbjct: 356 QKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQE 415
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKE-AEYAGQLAELRQRLDHAEADRQELQDELR 609
+ +Q +LEK+LE+ + + + KD E E A Q E ++RL+ RQEL ++
Sbjct: 416 WKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKN 475
Query: 610 QEREARQKLEMMIKELKLQI 629
+E+E +L K L L++
Sbjct: 476 REQEEIVRLNSKKKNLHLEL 495
Score = 32.3 bits (72), Expect = 1.4
Identities = 26/140 (18%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSS-----SKSMKELTEEQQNLQKELESLQ 540
+E++ ++QE++ + KK+ L +E++ L+ S ++++ ++Q + ELE L
Sbjct: 468 QELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLD 527
Query: 541 NE---HAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ +++ E ++ + KL ++ +K + E+ K +++ L
Sbjct: 528 KQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLN---ERIKNMQFSNTPDSGVSLLHKK 584
Query: 598 EADRQELQDELRQEREARQK 617
+++EL L+++ +A +K
Sbjct: 585 SLEKEELCQRLKEQLDALEK 604
Score = 30.4 bits (67), Expect = 5.2
Identities = 35/144 (24%), Positives = 70/144 (48%), Gaps = 23/144 (15%)
Query: 494 KQQEKLNLIL---QKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEF 550
KQ + +N L QK Q+ + + K+ + + ++ E+ N++ L+ ME+
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKANYERGNME-----LEKRRQALMEQ- 388
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQ 610
+Q++ E+K + K+K + + +E E+ QL EL +RL E Q EL +
Sbjct: 389 --QQREAERKAQ---KEKEEWERKQRELQEQEWKKQL-ELEKRL--------EKQRELER 434
Query: 611 EREARQKLEMMIKELKLQILKSSK 634
+RE ++ ++ +E Q L+ +
Sbjct: 435 QREEERRKDIERREAAKQELERQR 458
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/140 (28%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 496 QEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQ-----NLQKELESLQNEHAQRMEEF 550
Q+KL + + K++ E + K + L E+QQ QKE E + + + E+
Sbjct: 356 QKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQE 415
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKE-AEYAGQLAELRQRLDHAEADRQELQDELR 609
+ +Q +LEK+LE+ + + + KD E E A Q E ++RL+ RQEL ++
Sbjct: 416 WKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKN 475
Query: 610 QEREARQKLEMMIKELKLQI 629
+E+E +L K L L++
Sbjct: 476 REQEEIVRLNSKKKNLHLEL 495
Score = 32.3 bits (72), Expect = 1.4
Identities = 26/140 (18%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 486 EEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSS-----SKSMKELTEEQQNLQKELESLQ 540
+E++ ++QE++ + KK+ L +E++ L+ S ++++ ++Q + ELE L
Sbjct: 468 QELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLD 527
Query: 541 NE---HAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
+ +++ E ++ + KL ++ +K + E+ K +++ L
Sbjct: 528 KQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLN---ERIKNMQFSNTPDSGVSLLHKK 584
Query: 598 EADRQELQDELRQEREARQK 617
+++EL L+++ +A +K
Sbjct: 585 SLEKEELCQRLKEQLDALEK 604
Score = 30.4 bits (67), Expect = 5.2
Identities = 35/144 (24%), Positives = 70/144 (48%), Gaps = 23/144 (15%)
Query: 494 KQQEKLNLIL---QKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEF 550
KQ + +N L QK Q+ + + K+ + + ++ E+ N++ L+ ME+
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKANYERGNME-----LEKRRQALMEQ- 388
Query: 551 YVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQ 610
+Q++ E+K + K+K + + +E E+ QL EL +RL E Q EL +
Sbjct: 389 --QQREAERKAQ---KEKEEWERKQRELQEQEWKKQL-ELEKRL--------EKQRELER 434
Query: 611 EREARQKLEMMIKELKLQILKSSK 634
+RE ++ ++ +E Q L+ +
Sbjct: 435 QREEERRKDIERREAAKQELERQR 458
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 51.2 bits (121), Expect = 3e-06
Identities = 45/144 (31%), Positives = 84/144 (58%), Gaps = 13/144 (9%)
Query: 493 LKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQ-NLQKELESLQNEHAQRMEEFY 551
L+QQ++L L+LQ++ QLQ ++ ++ ++L E+QQ LQ++L Q E Q+ +
Sbjct: 235 LQQQQQL-LLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQ--- 290
Query: 552 VEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLD-HAEADRQEL--QDEL 608
+Q+ L+++ EQ+ +Q+ LE ++E E +L + + E RQEL Q EL
Sbjct: 291 -QQQLLQQQQEQLQQQQLQ-PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348
Query: 609 RQEREARQ---KLEMMIKELKLQI 629
+++E RQ KL+ +++L+ Q+
Sbjct: 349 ERQQEQRQLQLKLQEELQQLEQQL 372
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/156 (25%), Positives = 85/156 (54%), Gaps = 15/156 (9%)
Query: 478 EDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELE 537
E + + +E ++T Q+++ +LQ+++QLQ +V+ + +E ++QQ LQ++ E
Sbjct: 166 EQQRLQQQQEQLQTQQAQEQQ---VLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ-E 221
Query: 538 SLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHA 597
LQ + Q+ +E +Q+ L +++Q+ L + ++A+ QL E +Q A
Sbjct: 222 QLQQQQFQQQQEQLQQQQQL-----LLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ----A 272
Query: 598 EADRQEL--QDELRQEREARQKLEMMIKELKLQILK 631
+ +Q L Q E Q+++ +Q L+ ++L+ Q L+
Sbjct: 273 QLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ 308
Score = 47.0 bits (110), Expect = 5e-05
Identities = 39/155 (25%), Positives = 87/155 (56%), Gaps = 22/155 (14%)
Query: 496 QEKLNLILQKK------QQLQMEVKMLSSSKSMK-ELTEEQQNLQKELESLQNEHAQ--- 545
Q++L+ + Q+K Q+L+ E++++ + ++ + +EQQ LQ++ E LQ + AQ
Sbjct: 127 QQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQ 186
Query: 546 ------RMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEA 599
++++ EQ+ L+++ EQ+ +Q+ E+ ++ ++ Q +L+Q+
Sbjct: 187 VLQQQEQLQQQVQEQQLLQQQQEQLQQQQLL--QQQEQLQQQQFQQQQEQLQQQQQLLLL 244
Query: 600 DRQ-ELQDELRQEREA---RQKLEMMIKELKLQIL 630
+Q +LQ +L Q+++A +Q LE +L+ Q+L
Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLL 279
Score = 46.2 bits (108), Expect = 9e-05
Identities = 36/154 (23%), Positives = 85/154 (55%), Gaps = 19/154 (12%)
Query: 481 KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQN--LQKELES 538
+G++ +++++ +QQ +L L ++QQ Q++ ++L + ++L ++QQ LQ++ E
Sbjct: 247 QGQLQQQLLQ---QQQAQLQQQLLEQQQAQLQQQLLLQQQ--EQLQQQQQQQLLQQQQEQ 301
Query: 539 LQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAE 598
LQ + Q E++++E +L + +L ++E E Q E +Q L+ +
Sbjct: 302 LQQQQLQPPPLEPEEEEEVELELMPV---------DLGSEQELEQQRQELERQQELERQQ 352
Query: 599 ADRQ---ELQDELRQEREARQKLEMMIKELKLQI 629
RQ +LQ+EL+Q + ++ + +++ ++Q+
Sbjct: 353 EQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQL 386
Score = 44.7 bits (104), Expect = 3e-04
Identities = 29/146 (19%), Positives = 81/146 (55%), Gaps = 18/146 (12%)
Query: 483 KIMEEVMRTYLKQQEKLNLILQKKQQLQ----MEVKMLSSSKSMKELTEEQQNLQKELES 538
++M + + +Q ++ + Q+++QLQ E ++L + +++ +EQQ LQ++ E
Sbjct: 151 QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQ 210
Query: 539 LQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAE 598
LQ + + +E ++Q+ +++ EQ+ +Q+ + Q +L+Q+L +
Sbjct: 211 LQQQQLLQQQE-QLQQQQFQQQQEQLQQQQ-----------QLLLLQQQGQLQQQL--LQ 256
Query: 599 ADRQELQDELRQEREARQKLEMMIKE 624
+ +LQ +L ++++A+ + ++++++
Sbjct: 257 QQQAQLQQQLLEQQQAQLQQQLLLQQ 282
Score = 40.4 bits (93), Expect = 0.005
Identities = 35/138 (25%), Positives = 72/138 (52%), Gaps = 3/138 (2%)
Query: 495 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ 554
QQ + +L LQ++ Q Q + LS + K + Q L+ EL+ L ++ Q + EQ
Sbjct: 110 QQPQPHLELQQQPQ-QDGQQQLSQLQQEKHQSVHHQELKPELQ-LMHQQQQLQPQQVQEQ 167
Query: 555 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQEL-QDELRQERE 613
+ L+++ EQ+ Q+ L++ ++ + Q +L Q+ +Q L Q E Q+++
Sbjct: 168 QRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQ 227
Query: 614 ARQKLEMMIKELKLQILK 631
+Q+ E + ++ +L +L+
Sbjct: 228 FQQQQEQLQQQQQLLLLQ 245
Score = 32.7 bits (73), Expect = 1.1
Identities = 34/173 (19%), Positives = 81/173 (46%), Gaps = 34/173 (19%)
Query: 476 ICEDDKGKIMEEVM---RTYLKQQEKLNLILQKKQQLQM-----------EVKMLSSSKS 521
+ E + ++ ++++ + L+QQ++ L+ Q+++QLQ E + +
Sbjct: 266 LLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELM 325
Query: 522 MKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEA 581
+L EQ+ Q+ E + + +R +E Q L+++L+Q+ +
Sbjct: 326 PVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQ--------------- 370
Query: 582 EYAGQLAELRQRLDHAEADRQELQDEL-RQEREARQKLEMMIKELKLQILKSS 633
QL + +Q+L+ E + EL Q++E + +L + EL+L+++ ++
Sbjct: 371 ----QLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAA 419
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,425,358
Number of Sequences: 37866
Number of extensions: 1223172
Number of successful extensions: 11253
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 276
Number of HSP's successfully gapped in prelim test: 950
Number of HSP's that attempted gapping in prelim test: 5657
Number of HSP's gapped (non-prelim): 4447
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.