BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|222831647 KIAA1680 protein isoform 1 [Homo sapiens] (900 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|222831647 KIAA1680 protein isoform 1 [Homo sapiens] 1771 0.0 gi|46575934 KIAA1680 protein isoform 2 [Homo sapiens] 1315 0.0 gi|80861486 granule cell antiserum positive 14 [Homo sapiens] 92 2e-18 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 48 5e-05 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 45 2e-04 gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 45 3e-04 gi|60097902 filaggrin [Homo sapiens] 43 0.001 gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 42 0.002 gi|40068059 CBF1 interacting corepressor [Homo sapiens] 40 0.010 gi|33356174 pinin, desmosome associated protein [Homo sapiens] 40 0.013 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 40 0.013 gi|239752529 PREDICTED: similar to mucin [Homo sapiens] 39 0.028 gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 39 0.028 gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 39 0.028 gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 39 0.028 gi|50962882 G patch domain containing 8 [Homo sapiens] 38 0.037 gi|67782356 corneodesmosin precursor [Homo sapiens] 38 0.048 gi|196114970 protein tyrosine phosphatase, non-receptor type 12 ... 37 0.063 gi|196114967 protein tyrosine phosphatase, non-receptor type 12 ... 37 0.063 gi|196114951 protein tyrosine phosphatase, non-receptor type 12 ... 37 0.063 gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 37 0.063 gi|55741677 SET domain containing 1A [Homo sapiens] 37 0.083 gi|62988361 absent in melanoma 1 [Homo sapiens] 37 0.083 gi|21314720 Smad nuclear interacting protein [Homo sapiens] 37 0.083 gi|188497758 ubiquitin associated protein 2-like isoform a [Homo... 37 0.083 gi|188497756 ubiquitin associated protein 2-like isoform b [Homo... 37 0.083 gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 37 0.11 gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa... 37 0.11 gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ... 37 0.11 gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 37 0.11 >gi|222831647 KIAA1680 protein isoform 1 [Homo sapiens] Length = 900 Score = 1771 bits (4588), Expect = 0.0 Identities = 900/900 (100%), Positives = 900/900 (100%) Query: 1 MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRR 60 MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRR Sbjct: 1 MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRR 60 Query: 61 SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS 120 SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS Sbjct: 61 SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS 120 Query: 121 SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL 180 SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL Sbjct: 121 SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL 180 Query: 181 LPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGS 240 LPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGS Sbjct: 181 LPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGS 240 Query: 241 SLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNS 300 SLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNS Sbjct: 241 SLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNS 300 Query: 301 AAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSV 360 AAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSV Sbjct: 301 AAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSV 360 Query: 361 SHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP 420 SHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP Sbjct: 361 SHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP 420 Query: 421 TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDG 480 TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDG Sbjct: 421 TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDG 480 Query: 481 NIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDS 540 NIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDS Sbjct: 481 NIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDS 540 Query: 541 YHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNS 600 YHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNS Sbjct: 541 YHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNS 600 Query: 601 PSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVS 660 PSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVS Sbjct: 601 PSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVS 660 Query: 661 PLTEEPVPFKDIMKDECSMLKLQLKEKDELISQLQEELGKVRHLQKAFASRVDKSTQTEL 720 PLTEEPVPFKDIMKDECSMLKLQLKEKDELISQLQEELGKVRHLQKAFASRVDKSTQTEL Sbjct: 661 PLTEEPVPFKDIMKDECSMLKLQLKEKDELISQLQEELGKVRHLQKAFASRVDKSTQTEL 720 Query: 721 LCYDGLNLKRLETVQGGREATYRNRIVSQNLSTRDRKAIHTPTEDRFRYSAADQTSPYKN 780 LCYDGLNLKRLETVQGGREATYRNRIVSQNLSTRDRKAIHTPTEDRFRYSAADQTSPYKN Sbjct: 721 LCYDGLNLKRLETVQGGREATYRNRIVSQNLSTRDRKAIHTPTEDRFRYSAADQTSPYKN 780 Query: 781 KTCQLPSLCLSNFLKDKELAEVIKHSRGTYETLTSDVTQNLRATVGQSSLKPTAKTEGLS 840 KTCQLPSLCLSNFLKDKELAEVIKHSRGTYETLTSDVTQNLRATVGQSSLKPTAKTEGLS Sbjct: 781 KTCQLPSLCLSNFLKDKELAEVIKHSRGTYETLTSDVTQNLRATVGQSSLKPTAKTEGLS 840 Query: 841 TFLEKPKDQVATARQHSTFTGRFGQPPRGPISLHMYSRKNVFLHHNLHSTELQTLGQQDG 900 TFLEKPKDQVATARQHSTFTGRFGQPPRGPISLHMYSRKNVFLHHNLHSTELQTLGQQDG Sbjct: 841 TFLEKPKDQVATARQHSTFTGRFGQPPRGPISLHMYSRKNVFLHHNLHSTELQTLGQQDG 900 >gi|46575934 KIAA1680 protein isoform 2 [Homo sapiens] Length = 677 Score = 1315 bits (3404), Expect = 0.0 Identities = 670/670 (100%), Positives = 670/670 (100%) Query: 1 MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRR 60 MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRR Sbjct: 1 MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRR 60 Query: 61 SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS 120 SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS Sbjct: 61 SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS 120 Query: 121 SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL 180 SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL Sbjct: 121 SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL 180 Query: 181 LPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGS 240 LPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGS Sbjct: 181 LPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGS 240 Query: 241 SLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNS 300 SLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNS Sbjct: 241 SLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNS 300 Query: 301 AAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSV 360 AAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSV Sbjct: 301 AAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSV 360 Query: 361 SHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP 420 SHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP Sbjct: 361 SHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP 420 Query: 421 TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDG 480 TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDG Sbjct: 421 TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDG 480 Query: 481 NIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDS 540 NIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDS Sbjct: 481 NIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDS 540 Query: 541 YHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNS 600 YHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNS Sbjct: 541 YHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNS 600 Query: 601 PSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVS 660 PSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVS Sbjct: 601 PSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVS 660 Query: 661 PLTEEPVPFK 670 PLTEEPVPFK Sbjct: 661 PLTEEPVPFK 670 >gi|80861486 granule cell antiserum positive 14 [Homo sapiens] Length = 834 Score = 92.4 bits (228), Expect = 2e-18 Identities = 98/303 (32%), Positives = 137/303 (45%), Gaps = 46/303 (15%) Query: 443 LASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDGNIEEVNSLRKQRAGSSSSKMNS 502 L S + +R G E SS+GT L+P GN+ V S SS+MNS Sbjct: 486 LVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPI-GNVHPVGSYE-------SSEMNS 537 Query: 503 LDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDSYHSVVSCAAVVLTPMEPMIEMK 562 +D+LNNL SC+L++DDLMLD++ E+ L C D+ + V P E Sbjct: 538 IDILNNLESCDLEDDDLMLDVDLPEDAPLENVEC--DNMNRFDRPDRNVRQPQE---GFW 592 Query: 563 KREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNSPSADWPLQGVEENGG------- 615 KR + +LS D S +SR SP + PL E GG Sbjct: 593 KRPPQRWSGQEHYHLS---HPDHYHHHGKSDLSR--GSPYRESPLGHFESYGGMPFFQAQ 647 Query: 616 ------------IDSLPFRLMLQDCTAVKTLLLKMKRVL-QESADMSPASSTTSLPVSPL 662 +D + R M+QDCTAVKT LLK+KR+L Q S SLP SP Sbjct: 648 KMFVDVPENTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPE 707 Query: 663 TE--EPVPFKDIMKDECSMLKLQLKEKDELISQLQEELGKVRHL-----QKAFASRVDKS 715 E + V + + +E LK ++K+KDE I L+ +L +H+ ++ + DK Sbjct: 708 PEDGDKVYKNEDLLNEIKQLKDEIKKKDEKIQLLELQLA-TQHICHQKCKEEKCTYADKY 766 Query: 716 TQT 718 TQT Sbjct: 767 TQT 769 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 47.8 bits (112), Expect = 5e-05 Identities = 73/362 (20%), Positives = 138/362 (38%), Gaps = 7/362 (1%) Query: 27 DSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQN 86 DS SS SS N+ SS+ S ++ SS S+ S + S + S + N Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981 Query: 87 LS----ISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTE--DFEREKE 140 S S+ + S+ S + + S S S N + + ++ D + Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041 Query: 141 HSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQS 200 S + + + SS S+ DS + D + S + S SS S S Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101 Query: 201 ISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEF 260 S S S + + + + S S D ++ + SS S + ++ + S Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161 Query: 261 LALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMS 320 + + DS D+ S S S D+ +DS+ + ++ + +++ + + + S Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220 Query: 321 PGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSEREENIGLQ 380 + S ES+ ++S ++ ++ +S S S+SN +DS+ + G Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280 Query: 381 NG 382 NG Sbjct: 1281 NG 1282 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 45.4 bits (106), Expect = 2e-04 Identities = 69/302 (22%), Positives = 114/302 (37%), Gaps = 36/302 (11%) Query: 5 GSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFR 64 GSRR SR RS +R S S S ++ HS S S + S S S K RS + Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237 Query: 65 TPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNM-QKLSLEEHIKTRGRHSVGFSSSR 123 + S S K S K++ +++ S +K+ +++ S S+ Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSK 297 Query: 124 NKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPK 183 +K +RS E EK S ++ RS ++S R+ + Sbjct: 298 SKSRSRSQERRVEEEKRGSVSRG------------------------RSQEKSLRQSRSR 333 Query: 184 SFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQ 243 S S S+ +S+S + + S E ++ + R S +AGSS + Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKK 393 Query: 244 SPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSM----ASHCDNFGHNDSTSQMSLN 299 D + +++PS SVS+ +KS S +N G N T S + Sbjct: 394 KKKEDTDRSQSRSPSR-------SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRS 446 Query: 300 SA 301 ++ Sbjct: 447 NS 448 >gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial [Homo sapiens] Length = 909 Score = 45.1 bits (105), Expect = 3e-04 Identities = 69/300 (23%), Positives = 113/300 (37%), Gaps = 30/300 (10%) Query: 13 SRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNS-SSGSTGKRRSIFRTPSISFH 71 S P F SI + S+PS ++++ ++ ST S +S T + TPS + Sbjct: 26 SSTPSFTSSITTTETTSHSTPSFTSSISTTETTSHSTPSFTSLITITETTSHSTPSYTTS 85 Query: 72 HKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSL 131 P + SI+ P HS S +T + F+SS T S Sbjct: 86 ITTTETPSHSTPSYTTSITTTETPSHSTPSFTSSITTTETTSHSTPSFTSSIRTTETTS- 144 Query: 132 TEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKF 191 +ST N ++ S S T T + ST SFSS Sbjct: 145 ---------YSTPSFTSSNTITETTSHSTPSYITSITTTETPSSST-----PSFSSSITT 190 Query: 192 SKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADL 251 ++ S S S + E T + ++PS + +T +S +P ++ + Sbjct: 191 TETT--SHSTPGFTSSITTTETTSH---------STPSFTSSITTTETTSHDTPSFTSSI 239 Query: 252 TTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELT 311 TT++TPS + ++ + S S S + ++TS S +S + TTTE T Sbjct: 240 TTSETPSHSTPSSTSLITTTK--TTSHSTPSFTSSITTTETTSH-SAHSFTSSITTTETT 296 Score = 37.4 bits (85), Expect = 0.063 Identities = 82/400 (20%), Positives = 139/400 (34%), Gaps = 34/400 (8%) Query: 16 PIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGS-TGKRRSIFRTPSISFHHKK 74 P F SI+ + S+PS ++ + + ++ ST S + S T TPS + Sbjct: 46 PSFTSSISTTETTSHSTPSFTSLITITETTSHSTPSYTTSITTTETPSHSTPSYTTSITT 105 Query: 75 GSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRS---- 130 P + SI+ HS S +T + F+SS T S Sbjct: 106 TETPSHSTPSFTSSITTTETTSHSTPSFTSSIRTTETTSYSTPSFTSSNTITETTSHSTP 165 Query: 131 --LTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTE-----DQTRRSVKQSTRKLLPK 183 +T E S+ + + ++ + GFT + T S T + Sbjct: 166 SYITSITTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTT 225 Query: 184 SFSSHY--KFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSS 241 +SH F+ + S++ S S SL T ++PS + +T +S Sbjct: 226 ETTSHDTPSFTSSITTSETPSHSTPSSTSLITTT-----KTTSHSTPSFTSSITTTETTS 280 Query: 242 LQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSA 301 + ++ +TT +T S S++ + S S + + S S S +S+ Sbjct: 281 HSAHSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSS 340 Query: 302 AVTKTT-------TELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAE 354 T T T T P + L T S S+ L + Sbjct: 341 ITTTETXXXXXXXTSETAVTPTPVTPSS---LSTDIPTTSLRTLTPSSVGTSTSLTTTTD 397 Query: 355 LPATSVSHSESNLPADSE-REENIGLQNGET--MLGTNSP 391 P S+ S LP + + +Q+ ET ++GT SP Sbjct: 398 FP--SIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSP 435 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 43.1 bits (100), Expect = 0.001 Identities = 93/431 (21%), Positives = 148/431 (34%), Gaps = 52/431 (12%) Query: 21 SINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQ 80 S+++ DS S S G S + + G R + H +Q Sbjct: 3538 SVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQ 3597 Query: 81 EPTNQNLSISNG-AQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREK 139 T+ + S G A H + + E H H SSR+ I R+ Sbjct: 3598 SGTHHAENSSGGQAASSHEQARSSAGERH---GSHHQQSADSSRHSGIGHGQASSAVRDS 3654 Query: 140 EHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQ 199 H SSG D G +ED +SV S SH + ++ + Sbjct: 3655 GHRG---------SSGSQASDSEGHSEDSDTQSV--SAHGQAGPHQQSHQESTRGRSAGR 3703 Query: 200 SISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQT--- 256 S + F +V+ +++ E RA PS R + S SA T Sbjct: 3704 S---GRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRG 3760 Query: 257 -PSEFLALTEDSVSE--MDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGT 313 P + S E +D SGS SH + G +D++ S + +A +T E Sbjct: 3761 HPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNE---- 3816 Query: 314 VPCAIMSPGKYRLEG----QCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESN--L 367 S R G + ST+++S + + + + + +SVS + Sbjct: 3817 ----EQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAY 3872 Query: 368 PADSEREENIGLQN------GETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIPT 421 P DSER +N ++ G+ P H+ A HV+ SDS T Sbjct: 3873 PEDSERRSESASRNHHGSSREQSRDGSRHPG-----SSHRDTASHVQSSPVQSDSS---T 3924 Query: 422 SGDHHIFNKTS 432 + +H F+ S Sbjct: 3925 AKEHGHFSSLS 3935 Score = 38.1 bits (87), Expect = 0.037 Identities = 99/469 (21%), Positives = 162/469 (34%), Gaps = 59/469 (12%) Query: 21 SINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQ 80 S+++ DS S S G S + ++ G R F + H +Q Sbjct: 1269 SVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQ 1328 Query: 81 EPTNQNLSISNG-AQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREK 139 T+ S S+G A H + E H RH SSR+ I R+ Sbjct: 1329 SGTHHTESSSHGQAVSSHEQARSSPGERH---GSRHQQSADSSRHSGIGHRQASSAVRDS 1385 Query: 140 EHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQ 199 H SSG + G +ED +SV + H + K + Q Sbjct: 1386 GHRG---------SSGSQVTNSEGHSEDSDTQSVSAHGQA------GPHQQSHKESARGQ 1430 Query: 200 S-ISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQT-- 256 S S + F +V+ +++ E + +PS R + S SA T Sbjct: 1431 SGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIR 1490 Query: 257 --PSEFLALTEDSVSE--MDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTG 312 P + S E +D SG SH G +D++ S +A +T E Sbjct: 1491 GHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNE--- 1547 Query: 313 TVPCAIMSPGKYRLEG----QCSTESNSLPETSAANQKEVLLQIAELPATSVS------- 361 S R G + ST + S + + + + +SVS Sbjct: 1548 -----EQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEG 1602 Query: 362 HSE-SNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP 420 HSE S ++S + G ++ G+ +PR +++ +A H ++ Sbjct: 1603 HSEDSERRSESASRNHYGSAREQSRHGSRNPRS---HQEDRASHGH--------SAESSR 1651 Query: 421 TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAG 469 SG H +TS G +A ++ A S R G ++ SS++ G Sbjct: 1652 QSGTRHA--ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTG 1698 Score = 34.7 bits (78), Expect = 0.41 Identities = 103/471 (21%), Positives = 153/471 (32%), Gaps = 62/471 (13%) Query: 21 SINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQ 80 S+++ DS S S G S + + G R + H +Q Sbjct: 1917 SVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQ 1976 Query: 81 EPTNQNLSISNG-AQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREK 139 T S S G A H + + E H S SSR+ I R+ Sbjct: 1977 SGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSA--DSSRHSGIGHGQASSAVRDS 2034 Query: 140 EHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQ 199 H SG D G +ED +SV + H + K + Q Sbjct: 2035 GHRGY---------SGSQASDSEGHSEDSDTQSVSAQGKA------GPHQQSHKESARGQ 2079 Query: 200 S-ISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQT-- 256 S S + F +V+ +++ E +++PS + S SA T Sbjct: 2080 SGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIR 2139 Query: 257 ----PSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKT-TTELT 311 PS +D SGS SH + G +D++ S + +A KT E + Sbjct: 2140 GHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQS 2199 Query: 312 G------------TVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATS 359 G A S +GQ S S P S+ +Q + S Sbjct: 2200 GDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQ----------DSDS 2249 Query: 360 VSHSE-SNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKI 418 HSE S + S + G ++ G+ PR H+ A H H S+ Sbjct: 2250 EGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPR-----SHHEDRAGHG---HSAESSR- 2300 Query: 419 IPTSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAG 469 SG HH N S G +A + A S + R G ++ SS G Sbjct: 2301 --QSGTHHAEN--SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG 2347 Score = 30.8 bits (68), Expect = 5.9 Identities = 62/300 (20%), Positives = 102/300 (34%), Gaps = 32/300 (10%) Query: 21 SINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQ 80 S+++ DS S S G S + + G R + H +Q Sbjct: 2242 SVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ 2301 Query: 81 EPTNQNLSISNG-AQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREK 139 T+ + S G A H + + E H H SSR+ I R+ Sbjct: 2302 SGTHHAENSSGGQAASSHEQARSSAGERH---GSHHQQSADSSRHSGIGHGQASSAVRDS 2358 Query: 140 EHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQ 199 H SSG D G +ED +SV S SH + ++ + Sbjct: 2359 GHRG---------SSGSQASDSEGHSEDSDTQSV--SAHGQAGPHQQSHQESTRGRSAGR 2407 Query: 200 SISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSE 259 S + F +V+ +++ E R S R GS + S+ +T+Q + Sbjct: 2408 S---GRSGSFLYQVSTHEQSESAHGRTGTSTG----GRQGSHHKQARDSSRHSTSQEGQD 2460 Query: 260 FLALTEDSVSE----------MDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTE 309 + S S +D SGS SH + G +D++ S + +A +T + Sbjct: 2461 TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRND 2520 Score = 30.4 bits (67), Expect = 7.7 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 3/122 (2%) Query: 2 GDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRS 61 G SGSR ++ +R R +R S SS + HS + + S ++ ++ S Sbjct: 885 GQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGS 944 Query: 62 IFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSS 121 S S H + SE ++N S Q H + S H + R H S Sbjct: 945 SVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRS---HHEDRAGHGHSADS 1001 Query: 122 SR 123 SR Sbjct: 1002 SR 1003 >gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 [Homo sapiens] Length = 568 Score = 42.4 bits (98), Expect = 0.002 Identities = 68/287 (23%), Positives = 116/287 (40%), Gaps = 26/287 (9%) Query: 28 SLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNL 87 S SS SSS++ SSS SS++SSS S+ S + S S HK E K++P+ + Sbjct: 153 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSR 212 Query: 88 SISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLT--EDFEREKEHSTNK 145 + + + K S E K + + + +KI + E KE + Sbjct: 213 EHKSAFKEPSRDHNKSSKESSKKPKENKPL-----KEEKIVPKMAFKEPKPMSKEPKPDS 267 Query: 146 NVFINCLSSGKSEGDDS-----GFTEDQTRRSVKQSTRKLLPKSFSSH----YKFSKPVL 196 N+ ++SG+ + S +E+ + + K+S+ + L KSFSS S Sbjct: 268 NLL--TITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKK 325 Query: 197 QSQSISLVQQSEFSLEVTQYQEREPVLVR----ASPSCSVDVTERAGSSLQSPLLSADLT 252 Q + S V+ + +E ++++ L P+ S DV E S S S + Sbjct: 326 QIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASS 384 Query: 253 TAQTPSEFLALTEDSVSEMDAFSK---SGSMASHCDNFGHNDSTSQM 296 ++ + S F + + K S D ND+ S+M Sbjct: 385 SSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEM 431 >gi|40068059 CBF1 interacting corepressor [Homo sapiens] Length = 450 Score = 40.0 bits (92), Expect = 0.010 Identities = 43/159 (27%), Positives = 68/159 (42%), Gaps = 15/159 (9%) Query: 20 RSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKR--RSIFRTPSISFHHKKGSE 77 RS +++H S SS SSS++ +S SS+ S S + K+ R + S H+ SE Sbjct: 249 RSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSE 308 Query: 78 PKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFER 137 K + + L H N +K K + R SS + K + S ++ R Sbjct: 309 EKDKSKKRKL--HEELSSSHHNREK------AKEKPRFLKHESSREDSKWSHSDSDKKSR 360 Query: 138 EKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQS 176 +HS K S +S G E+++RRS +S Sbjct: 361 THKHSPEKRGSERKEGSSRSHG-----REERSRRSRSRS 394 >gi|33356174 pinin, desmosome associated protein [Homo sapiens] Length = 717 Score = 39.7 bits (91), Expect = 0.013 Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 25/161 (15%) Query: 20 RSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPK 79 RS +R +S S S + SSS SST+SSSGS+ GS Sbjct: 559 RSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSS---------------SSGSSSS 603 Query: 80 QEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSR--NKKITRSLTEDFER 137 + ++ + S S + S+ S E ++RGR G + R + + R + Sbjct: 604 RSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGR---GHNRDRKHRRSVDRKRRDTSGL 660 Query: 138 EKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTR 178 E+ H ++K SS ++G + +RS+ +S+R Sbjct: 661 ERSHKSSKGG-----SSRDTKGSKDKNSRSDRKRSISESSR 696 Score = 39.7 bits (91), Expect = 0.013 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 6/155 (3%) Query: 20 RSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPK 79 R+ N+ S S SSS++ +SS S ++SSSGS+ R S + S S + S Sbjct: 565 RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSS 624 Query: 80 QEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREK 139 ++++ S S G GH+ +K K R + S +K + T+ + + Sbjct: 625 TSSSSESRSRSRGR--GHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKN 682 Query: 140 EHSTNKNVFINCLSSGK----SEGDDSGFTEDQTR 170 S K SGK SE D +D+ R Sbjct: 683 SRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 39.7 bits (91), Expect = 0.013 Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 16/136 (11%) Query: 22 INRRHDSLPSSPSSSNTVGVH---SSSPSSTNSSSGSTGKRRSIFRTPSISFHH------ 72 ++R S P SP + G H SSSP+S N S G + +S TPS Sbjct: 430 VSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489 Query: 73 -KKGSEPKQEPTNQNLSISNGAQPGHS-NMQKLSLEEHIKTRGR----HSVGFSSSRNKK 126 K+G + PT + S S Q S + Q+ + RGR G+S SRN + Sbjct: 490 AKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ 549 Query: 127 ITRSLTEDFEREKEHS 142 R + R + HS Sbjct: 550 -RRGRSRSARRGRSHS 564 Score = 33.9 bits (76), Expect = 0.70 Identities = 53/210 (25%), Positives = 80/210 (38%), Gaps = 30/210 (14%) Query: 40 GVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSN 99 G HS SP+ SS S+ +RR RTP S +K S + P P + Sbjct: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTS---RKRSRSRTSPA-----------PWKRS 1864 Query: 100 MQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEG 159 + S H ++R R + S R++ T ++ R + T + +S S Sbjct: 1865 RSRASPATHRRSRSRTPL-ISRRRSRSRTSPVSRRRSRSRTSVTRRR--SRSRASPVSRR 1921 Query: 160 DDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQER 219 T TRR + T +S S + PV + +S S VT+ + R Sbjct: 1922 RSRSRTPPVTRRRSRSRTPTTRRRSRSR----TPPVTRRRSRSRTP------PVTRRRSR 1971 Query: 220 ---EPVLVRASPSCSVDVTERAGSSLQSPL 246 P+ R S S + VT R S SP+ Sbjct: 1972 SRTSPITRRRSRSRTSPVTRRRSRSRTSPV 2001 Score = 33.9 bits (76), Expect = 0.70 Identities = 31/130 (23%), Positives = 51/130 (39%), Gaps = 12/130 (9%) Query: 13 SRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHH 72 S L + + RR S SS SSS++ SSS SS++ SS S + S+ P ++ Sbjct: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578 Query: 73 ------------KKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS 120 ++G P+ P + S+ + S+ S + S S Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638 Query: 121 SSRNKKITRS 130 SS + + S Sbjct: 2639 SSSSSSSSSS 2648 Score = 31.6 bits (70), Expect = 3.5 Identities = 21/61 (34%), Positives = 31/61 (50%) Query: 24 RRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPT 83 +R S SS SSS++ SSS SS++SSS S+ S + S K G + +P Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA 2663 Query: 84 N 84 + Sbjct: 2664 S 2664 Score = 30.4 bits (67), Expect = 7.7 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Query: 19 RRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHH----KK 74 +R S SS SSS++ SSS SS++SSS S+ S +PS + K Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661 Query: 75 GSEPKQEPTNQNLSIS 90 + PK+ P + S S Sbjct: 2662 PASPKKPPPGERRSRS 2677 >gi|239752529 PREDICTED: similar to mucin [Homo sapiens] Length = 594 Score = 38.5 bits (88), Expect = 0.028 Identities = 81/362 (22%), Positives = 126/362 (34%), Gaps = 43/362 (11%) Query: 16 PIFRRSINRRHDSLPSSPSSSNTVGV-HSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKK 74 P F SI S PS ++ + S+S S + +S T + TPS + Sbjct: 103 PSFTSSIATTETPSHSPPSFTSLITTTESTSHSPLSFTSVITTTESTSHSTPSFTSSIAT 162 Query: 75 GSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTED 134 P + I+ P HSN SL ++ F+S+ T +T Sbjct: 163 TETTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFTSAI---ATTGITS- 218 Query: 135 FEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHY--KFS 192 HST +F + ++ T D T S T + SH FS Sbjct: 219 ------HSTP--IFTSLIA-----------TTDSTSHSTPSFTSSITSTETISHSTPSFS 259 Query: 193 KPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLT 252 + +++ S S SL T ++PS + VT +S +P ++ +T Sbjct: 260 SLITATKTTSHSTPSLTSLITTTNTSH------STPSLTSLVTSTETASHSTPSFTSLIT 313 Query: 253 TAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTT--EL 310 T + S S++ S S ++ + S S SL SA T T + Sbjct: 314 TIEATSHSTPSLTSSITTTGTTSHSTPSFTYLTTITESTSHSTPSLTSAITTTETMSHSI 373 Query: 311 TGTVPCAI--MSPGKYRLEGQCSTESNSLPE-------TSAANQKEVLLQIAELPATSVS 361 G P I +P L T S+S P T +A+ L A ++S Sbjct: 374 LGFTPSIISPSTPSYISLIATTETPSHSTPSFPSSITTTQSASHSTPSLTSAISTTEAMS 433 Query: 362 HS 363 HS Sbjct: 434 HS 435 Score = 36.2 bits (82), Expect = 0.14 Identities = 58/303 (19%), Positives = 109/303 (35%), Gaps = 22/303 (7%) Query: 28 SLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRT--------PSISFHHKKGSEPK 79 ++ ++ + S++ + +SS ++ ++S ST S+ T P+ +F Sbjct: 40 AITTTETRSHSPPIFTSSITTIETTSHSTPSFTSLMTTTETTSLSPPAFTFSISTTETNS 99 Query: 80 QEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSS-----SRNKKITRSLTED 134 P + SI+ P HS SL ++ + F+S T S T Sbjct: 100 HSPPSFTSSIATTETPSHSPPSFTSLITTTESTSHSPLSFTSVITTTESTSHSTPSFTSS 159 Query: 135 FEREKEHSTNKNVFINCLSSGKSEG-DDSGFTE-----DQTRRSVKQSTRKLLPKSFSSH 188 + S F + +++ ++ + FT + T S T + +SH Sbjct: 160 IATTETTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFTSAIATTGITSH 219 Query: 189 YKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLS 248 S P+ S + S + T + ++PS S +T +S +P L+ Sbjct: 220 ---STPIFTSLIATTDSTSHSTPSFTSSITSTETISHSTPSFSSLITATKTTSHSTPSLT 276 Query: 249 ADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTT 308 + +TT T +LT S A + S S ++ +S T TT+ Sbjct: 277 SLITTTNTSHSTPSLTSLVTSTETASHSTPSFTSLITTIEATSHSTPSLTSSITTTGTTS 336 Query: 309 ELT 311 T Sbjct: 337 HST 339 >gi|114155142 nuclear pore complex-associated protein TPR [Homo sapiens] Length = 2363 Score = 38.5 bits (88), Expect = 0.028 Identities = 71/319 (22%), Positives = 123/319 (38%), Gaps = 40/319 (12%) Query: 551 VLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNSPSADWPLQGV 610 +L + + E ++REE E L LKL E+ + + ++ S L Sbjct: 553 LLVALRELGETREREEQETTSSKITELQLKL------ESALTELEQLRKSRQHQMQL--- 603 Query: 611 EENGGIDSLP-----FRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVSPLTEE 665 +DS+ +R++L T V + L + S +P +TS VS T Sbjct: 604 -----VDSIVRQRDMYRILLSQTTGV-AIPLHASSLDDVSLASTPKRPSTSQTVS--TPA 655 Query: 666 PVPFKDIMKDECSMLKLQLKEKDELISQLQEELGKVRHLQKAFASRVD------KSTQTE 719 PVP I E K LK+ E+ ++E + +Q ++ +S T+ Sbjct: 656 PVPV--IESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTK 713 Query: 720 LLCYDGLNLKRLETVQGGREATYRNRIVSQNLSTRDRKAIHTPTEDRFRYSAADQTSPYK 779 + KR E +Q E YR I S L R++K T + + Q Sbjct: 714 ISTQLDFASKRYEMLQDNVEG-YRREITS--LHERNQKLTATTQKQEQIINTMTQDLRGA 770 Query: 780 NKTCQLPSLCLSNFLKDKELAEV--IKHSRGTYETLTSDVTQNLRAT-----VGQSSLKP 832 N+ + + N K+KE+ ++ ++ S+ L QNL T G Sbjct: 771 NEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSE 830 Query: 833 TAKTEGLSTFLEKPKDQVA 851 T + LS+ +EK + +++ Sbjct: 831 TETKQRLSSQIEKLEHEIS 849 >gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2 [Homo sapiens] Length = 1481 Score = 38.5 bits (88), Expect = 0.028 Identities = 38/156 (24%), Positives = 60/156 (38%), Gaps = 2/156 (1%) Query: 19 RRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEP 78 +RS++ SS S + S SP SS +RS+ R+P S K Sbjct: 299 QRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPS--RKSMKSR 356 Query: 79 KQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFERE 138 + P S S+ + S+ + S ++ S+G SR KK + + + Sbjct: 357 SRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMD 416 Query: 139 KEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVK 174 + S VF+ + E DSG + RSVK Sbjct: 417 GKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVK 452 >gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1 [Homo sapiens] Length = 1490 Score = 38.5 bits (88), Expect = 0.028 Identities = 38/156 (24%), Positives = 60/156 (38%), Gaps = 2/156 (1%) Query: 19 RRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEP 78 +RS++ SS S + S SP SS +RS+ R+P S K Sbjct: 299 QRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPS--RKSMKSR 356 Query: 79 KQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFERE 138 + P S S+ + S+ + S ++ S+G SR KK + + + Sbjct: 357 SRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMD 416 Query: 139 KEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVK 174 + S VF+ + E DSG + RSVK Sbjct: 417 GKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVK 452 >gi|50962882 G patch domain containing 8 [Homo sapiens] Length = 1502 Score = 38.1 bits (87), Expect = 0.037 Identities = 60/247 (24%), Positives = 96/247 (38%), Gaps = 30/247 (12%) Query: 3 DSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSS--PSSTNSSSGSTGKRR 60 D RRS LP S ++ + S S + H PSS +G+ R Sbjct: 752 DDSQRRS-----LPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSR 806 Query: 61 SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS 120 S R+ S G E + ++ L + +Q ++ S EH ++R R S Sbjct: 807 SSHRSQPSS-----GDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHS 861 Query: 121 SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDS-GFTEDQTRRSVKQS--- 176 S R+ + + S + D ++ +C S +S DDS D++RR K+S Sbjct: 862 SHRSSRRSYSSSSDASSDQ----------SCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS 911 Query: 177 --TRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDV 234 + K S +K+S S+S Q S T+ + R R+S SCS Sbjct: 912 DDSDYASSKHRSKRHKYSSSD-DDYSLSCSQSRSRSRSHTRERSRSRGRSRSS-SCSRSR 969 Query: 235 TERAGSS 241 ++R S Sbjct: 970 SKRRSRS 976 >gi|67782356 corneodesmosin precursor [Homo sapiens] Length = 529 Score = 37.7 bits (86), Expect = 0.048 Identities = 38/100 (38%), Positives = 46/100 (46%), Gaps = 19/100 (19%) Query: 29 LPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQN-- 86 L SS S S + G HS S SS +SSS S F+ S SF GS PTN N Sbjct: 134 LGSSSSHSGSSGSHSGSSSSHSSSSSS-------FQFSSSSFQVGNGS---ALPTNDNSY 183 Query: 87 LSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKK 126 I N +QPG S+ +T G S G S S N++ Sbjct: 184 RGILNPSQPGQSSSSS-------QTFGVSSSGQSVSSNQR 216 >gi|196114970 protein tyrosine phosphatase, non-receptor type 12 isoform 3 [Homo sapiens] Length = 650 Score = 37.4 bits (85), Expect = 0.063 Identities = 51/233 (21%), Positives = 91/233 (39%), Gaps = 21/233 (9%) Query: 143 TNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSIS 202 T++N ++C + ++ + E Q + + R L + + F P +I Sbjct: 360 TSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGP---ENAIP 416 Query: 203 LVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLA 262 + SE + YQ R+ V + SP+ V+ + SPL +TP F Sbjct: 417 IPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLF-------RTPLSFTN 469 Query: 263 LTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPG 322 S+ D + G++ + N ST+ ++++A T+TE T MS Sbjct: 470 PLHSDDSDSDERNSDGAVTQNKTNI----STASATVSAA----TSTESISTRKVLPMSIA 521 Query: 323 KYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSEREE 375 ++ + G +T S + + + L P + V SE N P SE E Sbjct: 522 RHNIAG--TTHSGAEKDVDVSEDSPPPLP-ERTPESFVLASEHNTPVRSEWSE 571 >gi|196114967 protein tyrosine phosphatase, non-receptor type 12 isoform 2 [Homo sapiens] Length = 661 Score = 37.4 bits (85), Expect = 0.063 Identities = 51/233 (21%), Positives = 91/233 (39%), Gaps = 21/233 (9%) Query: 143 TNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSIS 202 T++N ++C + ++ + E Q + + R L + + F P +I Sbjct: 371 TSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGP---ENAIP 427 Query: 203 LVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLA 262 + SE + YQ R+ V + SP+ V+ + SPL +TP F Sbjct: 428 IPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLF-------RTPLSFTN 480 Query: 263 LTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPG 322 S+ D + G++ + N ST+ ++++A T+TE T MS Sbjct: 481 PLHSDDSDSDERNSDGAVTQNKTNI----STASATVSAA----TSTESISTRKVLPMSIA 532 Query: 323 KYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSEREE 375 ++ + G +T S + + + L P + V SE N P SE E Sbjct: 533 RHNIAG--TTHSGAEKDVDVSEDSPPPLP-ERTPESFVLASEHNTPVRSEWSE 582 >gi|196114951 protein tyrosine phosphatase, non-receptor type 12 isoform 1 [Homo sapiens] Length = 780 Score = 37.4 bits (85), Expect = 0.063 Identities = 51/233 (21%), Positives = 91/233 (39%), Gaps = 21/233 (9%) Query: 143 TNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSIS 202 T++N ++C + ++ + E Q + + R L + + F P +I Sbjct: 490 TSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGP---ENAIP 546 Query: 203 LVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLA 262 + SE + YQ R+ V + SP+ V+ + SPL +TP F Sbjct: 547 IPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLF-------RTPLSFTN 599 Query: 263 LTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPG 322 S+ D + G++ + N ST+ ++++A T+TE T MS Sbjct: 600 PLHSDDSDSDERNSDGAVTQNKTNI----STASATVSAA----TSTESISTRKVLPMSIA 651 Query: 323 KYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSEREE 375 ++ + G +T S + + + L P + V SE N P SE E Sbjct: 652 RHNIAG--TTHSGAEKDVDVSEDSPPPLP-ERTPESFVLASEHNTPVRSEWSE 701 >gi|59710093 G-protein coupled receptor 112 [Homo sapiens] Length = 3080 Score = 37.4 bits (85), Expect = 0.063 Identities = 53/245 (21%), Positives = 100/245 (40%), Gaps = 13/245 (5%) Query: 140 EHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQ 199 +H F+ CL ++ + ++ +V ++ R +P++ + K SQ Sbjct: 189 DHILENEEFMKCLDGNIVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQ---EKSTTVSQ 245 Query: 200 SISLVQQSEFSLEVTQYQEREPVLVRAS-PSCSVDVTERAGSSLQSPLLSADLTTAQTPS 258 I + S+ + Q L+ S P + D T + S+ SP L + TAQ Sbjct: 246 QIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL--ETMTAQKIL 303 Query: 259 EFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLN---SAAVTKTT--TELTGT 313 + L + E + +D S S +++ + +++T+ M S+ TKTT E T Sbjct: 304 KTL-VDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMAT 362 Query: 314 VPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSER 373 +P + L T+++ + TSA + + + L +T S S S P ++ Sbjct: 363 EIFQPPTPSNF-LSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQK 421 Query: 374 EENIG 378 N G Sbjct: 422 STNTG 426 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 37.0 bits (84), Expect = 0.083 Identities = 57/235 (24%), Positives = 81/235 (34%), Gaps = 41/235 (17%) Query: 60 RSIFRTPSISFHHKKGSE--------------PKQEPTNQNLSISNGAQPGHSNMQKLSL 105 R R PS K+ SE P +E + +PG + Sbjct: 885 RGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKR 944 Query: 106 -EEHIKTRGRHSVGF-------------SSSRNKKITRSLTEDFEREKEHSTNKNVFINC 151 EE KT+G+H F SS ++++ ED +RE+ T K Sbjct: 945 DEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKE--TE 1002 Query: 152 LSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEFSL 211 +S G+ E DS S ++ +S SS S S S S SE S Sbjct: 1003 VSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSS 1062 Query: 212 EVTQYQEREPVLVRASP-----------SCSVDVTERAGSSLQSPLLSADLTTAQ 255 E + +ER L ASP V V ER S +PL + + A+ Sbjct: 1063 EDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPAR 1117 >gi|62988361 absent in melanoma 1 [Homo sapiens] Length = 1723 Score = 37.0 bits (84), Expect = 0.083 Identities = 118/556 (21%), Positives = 213/556 (38%), Gaps = 87/556 (15%) Query: 93 AQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFI--- 149 A+P H + L +++ + G FS +K T + FE ++ +S+ ++ I Sbjct: 235 AKPKHVELN-LKTPKNLDSLGNEHNPFSQPVHKGNTATKISLFENKRTNSSPRHTDIRGQ 293 Query: 150 -NCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSE 208 N +S K+ + + + ++Q +K++P S Q+ LV+++ Sbjct: 294 RNTPASSKTFVGRAKLNLAKKAKEMEQPEKKVMPNS-------------PQNGVLVKETA 340 Query: 209 FSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQ-SPLLSADLTT-AQTPSEFLALTED 266 +VT +E ++ A+ + D +E Q + AD+ T A SE +A Sbjct: 341 IETKVTVSEEE---ILPATRGMNGDSSENQALGPQPNQDDKADVQTDAGCLSEPVASALI 397 Query: 267 SVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPGKYRL 326 V + K S A+ + + T ++A TT + P A+ P Sbjct: 398 PVKDHKLLEKEDSEAADSKSLVLENVT-----DTAQDIPTTVDTKDLPPTAMPKPQHTFS 452 Query: 327 EGQCSTESNSLPETSAANQ------KEVLLQ--IAELPATSVSHSESN----LPADSERE 374 + Q ES+ P S + K+ +Q I+ P T + SE++ LP + Sbjct: 453 DSQSPAESSPGPSLSLSAPAPGDVPKDTCVQSPISSFPCTDLKVSENHKGCVLPVSRQNN 512 Query: 375 ENIGLQN--GETM--LGTN-SPRKLGFYEQHKAIAEHVKGIHPISD-----SKIIPTSGD 424 E + L GET L T SP +G + + + + P+ S++IP S + Sbjct: 513 EKMPLLELGGETTPPLSTERSPEAVGSECPSRVLVQVRSFVLPVESTQDVSSQVIPESSE 572 Query: 425 -HHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDGNIE 483 + T H E P V +S +P +E ++E A S ++ P E Sbjct: 573 VREVQLPTCHSNE--PEVVSVASCAPPQEEVLGNEHSHCTAELAAKSGPQVIPPAS---E 627 Query: 484 EVNSLRKQRAGS------SSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCR 537 + ++ Q GS SS NS N+L + + D + + + L+ S Sbjct: 628 KTLPIQAQSQGSRTPLMAESSPTNSPSSGNHLATPQRP-DQTVTNGQDSPASLLNISAGS 686 Query: 538 EDSYHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRM 597 +DS S ME E+ K+ + P K+ + RM Sbjct: 687 DDSVFDSSS-------DMEKFTEIIKQMDSAVCMPMKRKKA-----------------RM 722 Query: 598 PNSPSADWPLQGVEEN 613 PNSP+ + + + E+ Sbjct: 723 PNSPAPHFAMPPIHED 738 >gi|21314720 Smad nuclear interacting protein [Homo sapiens] Length = 396 Score = 37.0 bits (84), Expect = 0.083 Identities = 31/123 (25%), Positives = 48/123 (39%), Gaps = 7/123 (5%) Query: 40 GVHSSSPSSTNSSSGSTGKR-RSIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHS 98 G S P+S + SG G R R + R+P + G K + +N S P HS Sbjct: 50 GGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRS------PHHS 103 Query: 99 NMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSE 158 ++ E RGR ++ R+ D +R + HS + SG+ + Sbjct: 104 TVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQ 163 Query: 159 GDD 161 G D Sbjct: 164 GRD 166 >gi|188497758 ubiquitin associated protein 2-like isoform a [Homo sapiens] Length = 1087 Score = 37.0 bits (84), Expect = 0.083 Identities = 77/412 (18%), Positives = 146/412 (35%), Gaps = 47/412 (11%) Query: 30 PSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSI 89 PSSP S + SP S+++ S S + + KK S + P L++ Sbjct: 452 PSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQ-----KLKQQKKKASLTSKIPA---LAV 503 Query: 90 SNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFI 149 PG +++ L+L+ G V D+E S + + Sbjct: 504 E---MPGSADISGLNLQFGALQFGSEPV--------------LSDYESTPTTSASSSQAP 546 Query: 150 NCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEF 209 + L + + S + +Q++ S QS + +++S P+ + +S Sbjct: 547 SSLYTSTASESSSTISSNQSQESGYQS-GPIQSTTYTSQNNAQGPLYEQRSTQ------- 598 Query: 210 SLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLALTEDSVS 269 R P + +SP + + SS+Q+ L + + S S Sbjct: 599 -------TRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTS 651 Query: 270 EMDAFSKSGSMASHCDNFG-HNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPGKYRLEG 328 + +++ S AS H+ S +S + TTT+ + T+ + G Sbjct: 652 SIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSG 711 Query: 329 QCSTESNSLPETSAANQKEVLLQIAELPATSVSHSES----NLPADSEREENIGLQNGET 384 + ST ++L TS ++ + + TS + S ++ + ++GL G Sbjct: 712 RTST--STLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSN 769 Query: 385 MLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIPTSGDHHIFNKTSHGYE 436 T S R KA G+ P+ + I G H + +GY+ Sbjct: 770 STVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYD 821 >gi|188497756 ubiquitin associated protein 2-like isoform b [Homo sapiens] Length = 983 Score = 37.0 bits (84), Expect = 0.083 Identities = 77/412 (18%), Positives = 146/412 (35%), Gaps = 47/412 (11%) Query: 30 PSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSI 89 PSSP S + SP S+++ S S + + KK S + P L++ Sbjct: 452 PSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQ-----KLKQQKKKASLTSKIPA---LAV 503 Query: 90 SNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFI 149 PG +++ L+L+ G V D+E S + + Sbjct: 504 E---MPGSADISGLNLQFGALQFGSEPV--------------LSDYESTPTTSASSSQAP 546 Query: 150 NCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEF 209 + L + + S + +Q++ S QS + +++S P+ + +S Sbjct: 547 SSLYTSTASESSSTISSNQSQESGYQS-GPIQSTTYTSQNNAQGPLYEQRSTQ------- 598 Query: 210 SLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLALTEDSVS 269 R P + +SP + + SS+Q+ L + + S S Sbjct: 599 -------TRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTS 651 Query: 270 EMDAFSKSGSMASHCDNFG-HNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPGKYRLEG 328 + +++ S AS H+ S +S + TTT+ + T+ + G Sbjct: 652 SIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSG 711 Query: 329 QCSTESNSLPETSAANQKEVLLQIAELPATSVSHSES----NLPADSEREENIGLQNGET 384 + ST ++L TS ++ + + TS + S ++ + ++GL G Sbjct: 712 RTST--STLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSN 769 Query: 385 MLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIPTSGDHHIFNKTSHGYE 436 T S R KA G+ P+ + I G H + +GY+ Sbjct: 770 STVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYD 821 >gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sapiens] Length = 987 Score = 36.6 bits (83), Expect = 0.11 Identities = 133/693 (19%), Positives = 246/693 (35%), Gaps = 75/693 (10%) Query: 39 VGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHS 98 +G HS P + +T KR I S + + P+N S+S+ Sbjct: 1 MGNHSGRPEDPEPGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTP 60 Query: 99 NMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSG--K 156 K K + + G ++ ++ L E ++ E + ++ Sbjct: 61 TPTKHLRTPSTKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTLN 120 Query: 157 SEGDDS-GFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQ 215 +EG D+ G D T SV + + ++ K Q + L +++ E Sbjct: 121 AEGTDALGPNVDGT--SVSPGDTEPMIRALEEKNK----NFQKELSDLEEENRVLKEKLI 174 Query: 216 YQEREPVLVRAS-----PSCSVDVTERAGSSLQSPL---LSADLTTAQTPSEFLALTEDS 267 Y E P A+ SC +T+ SS SP +S+D+ + AL Sbjct: 175 YLEHSPNSEGAASHTGDSSCPTSITQE--SSFGSPTGNQMSSDIDEYKKNIHGNALRTSG 232 Query: 268 VSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPGKYRLE 327 S D S++ +F H T E + +P K Sbjct: 233 SSSSDV--TKASLSPDASDFEH----------------ITAETPSRPLSSTSNPFKSSKC 274 Query: 328 GQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSERE--------ENIGL 379 + NS+ E S A+ E + ++ E ++ ++ L S+++ EN L Sbjct: 275 STAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKL 334 Query: 380 QNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIPTSGDHHIFNKTSHGYEANP 439 + +T+L T+ + QH+ AE + +++ + + N+ E Sbjct: 335 VDEKTILETS-------FHQHRERAEQLS-----QENEKLMNLLQERVKNEEPTTQEGKI 382 Query: 440 AKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDGNIEEVNSLRKQRAGSSSSK 499 ++ +GRF +L + + S R + + G +E + L+++ + K Sbjct: 383 IELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEE-----NEK 437 Query: 500 MNSLDVL----NNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDSYHSVVSCAAVVLTPM 555 +N L NN+ + L+E + L+ +E SL + E + S Sbjct: 438 LNEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESC 497 Query: 556 EPMIEMK-KREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNSPSADWP-LQGVEEN 613 E +K R E + E S L +L K H+S + D+ L+ + ++ Sbjct: 498 EVQEMLKVARAEKDLLELSCNELRQELLK---ANGEIKHVSSLLAKVEKDYSYLKEICDH 554 Query: 614 GGIDSLPFRLMLQDCTAVKTLLLK-MKRVLQESADMSPASSTTSLPVSPLTEEPVPFKDI 672 L LQ+ + +K MK + E D L + L E Sbjct: 555 QAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIK 614 Query: 673 MKDECSMLKLQLKEKDELISQLQEELGKVRHLQ 705 ++++ S L+ QLK L Q++EE + R Q Sbjct: 615 LEEQKSDLERQLK---TLTKQMKEETEEWRRFQ 644 >gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sapiens] Length = 709 Score = 36.6 bits (83), Expect = 0.11 Identities = 133/693 (19%), Positives = 246/693 (35%), Gaps = 75/693 (10%) Query: 39 VGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHS 98 +G HS P + +T KR I S + + P+N S+S+ Sbjct: 1 MGNHSGRPEDPEPGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTP 60 Query: 99 NMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSG--K 156 K K + + G ++ ++ L E ++ E + ++ Sbjct: 61 TPTKHLRTPSTKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTLN 120 Query: 157 SEGDDS-GFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQ 215 +EG D+ G D T SV + + ++ K Q + L +++ E Sbjct: 121 AEGTDALGPNVDGT--SVSPGDTEPMIRALEEKNK----NFQKELSDLEEENRVLKEKLI 174 Query: 216 YQEREPVLVRAS-----PSCSVDVTERAGSSLQSPL---LSADLTTAQTPSEFLALTEDS 267 Y E P A+ SC +T+ SS SP +S+D+ + AL Sbjct: 175 YLEHSPNSEGAASHTGDSSCPTSITQE--SSFGSPTGNQMSSDIDEYKKNIHGNALRTSG 232 Query: 268 VSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPGKYRLE 327 S D S++ +F H T E + +P K Sbjct: 233 SSSSDV--TKASLSPDASDFEH----------------ITAETPSRPLSSTSNPFKSSKC 274 Query: 328 GQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSERE--------ENIGL 379 + NS+ E S A+ E + ++ E ++ ++ L S+++ EN L Sbjct: 275 STAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKL 334 Query: 380 QNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIPTSGDHHIFNKTSHGYEANP 439 + +T+L T+ + QH+ AE + +++ + + N+ E Sbjct: 335 VDEKTILETS-------FHQHRERAEQLS-----QENEKLMNLLQERVKNEEPTTQEGKI 382 Query: 440 AKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDGNIEEVNSLRKQRAGSSSSK 499 ++ +GRF +L + + S R + + G +E + L+++ + K Sbjct: 383 IELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEE-----NEK 437 Query: 500 MNSLDVL----NNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDSYHSVVSCAAVVLTPM 555 +N L NN+ + L+E + L+ +E SL + E + S Sbjct: 438 LNEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESC 497 Query: 556 EPMIEMK-KREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNSPSADWP-LQGVEEN 613 E +K R E + E S L +L K H+S + D+ L+ + ++ Sbjct: 498 EVQEMLKVARAEKDLLELSCNELRQELLK---ANGEIKHVSSLLAKVEKDYSYLKEICDH 554 Query: 614 GGIDSLPFRLMLQDCTAVKTLLLK-MKRVLQESADMSPASSTTSLPVSPLTEEPVPFKDI 672 L LQ+ + +K MK + E D L + L E Sbjct: 555 QAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIK 614 Query: 673 MKDECSMLKLQLKEKDELISQLQEELGKVRHLQ 705 ++++ S L+ QLK L Q++EE + R Q Sbjct: 615 LEEQKSDLERQLK---TLTKQMKEETEEWRRFQ 644 >gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo sapiens] Length = 2542 Score = 36.6 bits (83), Expect = 0.11 Identities = 42/178 (23%), Positives = 71/178 (39%), Gaps = 12/178 (6%) Query: 30 PSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSI 89 P S +++ T+G+ ++S + TN KR ++ TPS + +KK + PT + Sbjct: 1506 PPSATTTTTIGISATSATFTNVFGK---KRANVVTTPSTNRKNKKNKTKETPPTAHLILP 1562 Query: 90 SNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFI 149 K + + RG + G S S N T +E K N F+ Sbjct: 1563 EQHMSLAQQKADKNKING--EPRGGGAGGNSDSDNLDSTDCNSESSSGGKSQELN---FV 1617 Query: 150 NCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL----LPKSFSSHYKFSKPVLQSQSISL 203 ++S K E++T + ++ +L P S S+ YK L S +I L Sbjct: 1618 MDVNSSKYPSLLLHSQEEKTSTATSKTQTRLEGEVTPNSLSTSYKTVSLPLSSPNIKL 1675 >gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] Length = 2617 Score = 36.6 bits (83), Expect = 0.11 Identities = 42/178 (23%), Positives = 71/178 (39%), Gaps = 12/178 (6%) Query: 30 PSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSI 89 P S +++ T+G+ ++S + TN KR ++ TPS + +KK + PT + Sbjct: 1506 PPSATTTTTIGISATSATFTNVFGK---KRANVVTTPSTNRKNKKNKTKETPPTAHLILP 1562 Query: 90 SNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFI 149 K + + RG + G S S N T +E K N F+ Sbjct: 1563 EQHMSLAQQKADKNKING--EPRGGGAGGNSDSDNLDSTDCNSESSSGGKSQELN---FV 1617 Query: 150 NCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL----LPKSFSSHYKFSKPVLQSQSISL 203 ++S K E++T + ++ +L P S S+ YK L S +I L Sbjct: 1618 MDVNSSKYPSLLLHSQEEKTSTATSKTQTRLEGEVTPNSLSTSYKTVSLPLSSPNIKL 1675 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.125 0.345 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,333,014 Number of Sequences: 37866 Number of extensions: 1600487 Number of successful extensions: 6891 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 162 Number of HSP's that attempted gapping in prelim test: 6187 Number of HSP's gapped (non-prelim): 672 length of query: 900 length of database: 18,247,518 effective HSP length: 111 effective length of query: 789 effective length of database: 14,044,392 effective search space: 11081025288 effective search space used: 11081025288 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.