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Search of human proteins with 222537754
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222537754 hypothetical protein LOC375337 [Homo sapiens]
(1692 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222537754 hypothetical protein LOC375337 [Homo sapiens] 3381 0.0
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi... 47 2e-04
gi|147903302 MAP7 domain containing 3 [Homo sapiens] 47 2e-04
gi|150418007 RAN binding protein 2 [Homo sapiens] 45 6e-04
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi... 43 0.002
gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapi... 43 0.002
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 43 0.002
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 43 0.002
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 43 0.003
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 43 0.003
gi|58530840 desmoplakin isoform I [Homo sapiens] 42 0.007
gi|55770834 centromere protein F [Homo sapiens] 40 0.015
gi|38044112 restin isoform b [Homo sapiens] 39 0.033
gi|4506751 restin isoform a [Homo sapiens] 39 0.033
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 39 0.033
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 39 0.043
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 39 0.056
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 39 0.056
gi|45505178 cancer antigen 1 [Homo sapiens] 39 0.056
gi|156139122 CXXC finger 6 [Homo sapiens] 38 0.073
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 38 0.073
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 38 0.095
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 37 0.12
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 37 0.12
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 37 0.12
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 37 0.12
gi|45439327 periplakin [Homo sapiens] 37 0.12
gi|221219020 NYD-SP11 protein [Homo sapiens] 37 0.16
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] 37 0.16
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens] 37 0.16
>gi|222537754 hypothetical protein LOC375337 [Homo sapiens]
Length = 1692
Score = 3381 bits (8767), Expect = 0.0
Identities = 1692/1692 (100%), Positives = 1692/1692 (100%)
Query: 1 MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGR 60
MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGR
Sbjct: 1 MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGR 60
Query: 61 GEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKR 120
GEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKR
Sbjct: 61 GEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKR 120
Query: 121 KVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLEN 180
KVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLEN
Sbjct: 121 KVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLEN 180
Query: 181 PPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCND 240
PPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCND
Sbjct: 181 PPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCND 240
Query: 241 ENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDL 300
ENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDL
Sbjct: 241 ENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDL 300
Query: 301 YQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELML 360
YQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELML
Sbjct: 301 YQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELML 360
Query: 361 QENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTI 420
QENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTI
Sbjct: 361 QENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTI 420
Query: 421 EPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKL 480
EPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKL
Sbjct: 421 EPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKL 480
Query: 481 SCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTH 540
SCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTH
Sbjct: 481 SCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTH 540
Query: 541 LTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEE 600
LTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEE
Sbjct: 541 LTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEE 600
Query: 601 LSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIH 660
LSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIH
Sbjct: 601 LSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIH 660
Query: 661 RKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDN 720
RKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDN
Sbjct: 661 RKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDN 720
Query: 721 LSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNS 780
LSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNS
Sbjct: 721 LSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNS 780
Query: 781 KPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRK 840
KPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRK
Sbjct: 781 KPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRK 840
Query: 841 ITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGE 900
ITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGE
Sbjct: 841 ITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGE 900
Query: 901 HQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEV 960
HQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEV
Sbjct: 901 HQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEV 960
Query: 961 ANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGEC 1020
ANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGEC
Sbjct: 961 ANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGEC 1020
Query: 1021 QFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKN 1080
QFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKN
Sbjct: 1021 QFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKN 1080
Query: 1081 VGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELC 1140
VGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELC
Sbjct: 1081 VGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELC 1140
Query: 1141 LLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLK 1200
LLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLK
Sbjct: 1141 LLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLK 1200
Query: 1201 ILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAV 1260
ILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAV
Sbjct: 1201 ILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAV 1260
Query: 1261 LEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFC 1320
LEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFC
Sbjct: 1261 LEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFC 1320
Query: 1321 ACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSK 1380
ACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSK
Sbjct: 1321 ACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSK 1380
Query: 1381 GRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWI 1440
GRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWI
Sbjct: 1381 GRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWI 1440
Query: 1441 INTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSL 1500
INTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSL
Sbjct: 1441 INTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSL 1500
Query: 1501 LFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSA 1560
LFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSA
Sbjct: 1501 LFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSA 1560
Query: 1561 LSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKR 1620
LSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKR
Sbjct: 1561 LSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKR 1620
Query: 1621 CEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENM 1680
CEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENM
Sbjct: 1621 CEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENM 1680
Query: 1681 KWAGKVWLFSNH 1692
KWAGKVWLFSNH
Sbjct: 1681 KWAGKVWLFSNH 1692
>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens]
Length = 1758
Score = 47.0 bits (110), Expect = 2e-04
Identities = 62/243 (25%), Positives = 99/243 (40%), Gaps = 30/243 (12%)
Query: 699 RKEVNAKSSEREAYSPLELLDNLSGADVR---QNRSKENVSMMMLGPQTLSIRNSVTPVQ 755
R+EV A E + L+L + S + R +N ++V G QT + V
Sbjct: 816 RQEVKAIKEEMQE---LKLNSSKSASHHRWPTENYGPDSVPDGYQGSQTF--HGAPLTVA 870
Query: 756 ASSDSFYNKKSYSISPSFTKQGNNSKPSNHVSEPGN----IVSNKEVASLTVENNAFS-- 809
+ S Y YS SP++ Q +N G+ S KE S+ V + F
Sbjct: 871 TTGPSVY----YSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFG 926
Query: 810 -CDPGYVEKSPSFCCNEQETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLI 864
+PG EK F+ +S + GR + + S F D+ K+ +
Sbjct: 927 ISEPGNQEKESEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQF 986
Query: 865 DVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLREL 924
+ DP+ G S GE F+S+ K++ + N +G+ + D Y K E SDD+
Sbjct: 987 G--KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDAY-----KTEDSDDIHFE 1039
Query: 925 PVL 927
PV+
Sbjct: 1040 PVV 1042
>gi|147903302 MAP7 domain containing 3 [Homo sapiens]
Length = 876
Score = 46.6 bits (109), Expect = 2e-04
Identities = 120/588 (20%), Positives = 224/588 (38%), Gaps = 51/588 (8%)
Query: 104 KEAELPLQTERHTKEK-RKVTEASSDDPQPGLDLVRK---ESLTSSESFQTVECLQSLGK 159
KE + LQ E+ +E+ RK+ E + Q + K + E F + ++L +
Sbjct: 94 KERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAI-LYRTLER 152
Query: 160 ESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEF-QDELYKNTPKYSCNILSP-- 216
+ + +++ + ++ N K + K+E L + P S + +
Sbjct: 153 RRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVA 212
Query: 217 ----EVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFS------KKENLR 266
+ E +S L RD N HS ++ + G +V + + + LR
Sbjct: 213 KRKTDKERSSSLNRRDSNL--HSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELR 270
Query: 267 SLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSV 326
++ T IP + EE+ + + P+ S + N + C + + ++ V
Sbjct: 271 AVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFC---NTSMEASPKAGV 327
Query: 327 GRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSH 386
G P V+ + + + SE+ + + ++ EA K L + KVS
Sbjct: 328 GMAPEVSTDSFPVVSVDVSPVVSTYD---SEMSMDASPELSI--EALPKVDLETVPKVS- 381
Query: 387 NTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDF 446
V+ + L P V E E V A + ++E K E A P + KE
Sbjct: 382 -IVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVA--PKESVKGSPKESM 438
Query: 447 KSMKSFIGKSPNEYHIE---RRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARIS 503
++ + K+ + +E S + R A ++ ++ Q IP+ KR Y C + S
Sbjct: 439 EASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWS 498
Query: 504 AWCWKKASLPESSYFLRGSQESCRQVDVP--KHQTNQTHLTDSKLLLQSSLTETNTESSS 561
+ LP R Q++C +P Q+ QT + +Q +L+ + S+
Sbjct: 499 SSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTV 558
Query: 562 KEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELS-------RRGSEVISNTTE 614
K+K ++ S + A+ M+ +E K I + E + RR + E
Sbjct: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEE 618
Query: 615 DTQLTSETQSLTGNK-----KKARGNLTKLNLTATSKDGQEANNSAGK 657
+ + E Q K K+A G + +L KDGQ+ N + K
Sbjct: 619 EERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKL--KDGQQQNETKKK 664
>gi|150418007 RAN binding protein 2 [Homo sapiens]
Length = 3224
Score = 45.1 bits (105), Expect = 6e-04
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 23/165 (13%)
Query: 770 SPSFTKQGNNSKPSNHVSEPGNIVSNKEVASLTVENNAFS---CDPGYVEKSPSFCCNEQ 826
SPSF QG+++ S KE S+ V + F +PG EK
Sbjct: 1869 SPSFMFQGSSNT---------EFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG 1919
Query: 827 ETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGEL 882
F+ +S + GR + + S F D+ K+ + + DP+ G S GE
Sbjct: 1920 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFG--KKDPNFKGFSGAGEK 1977
Query: 883 SFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVL 927
F+S+ K++ + N +G+ + D Y K E SDD+ PV+
Sbjct: 1978 LFSSQYGKMANKANTSGDFEKDDDAY-----KTEDSDDIHFEPVV 2017
>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapiens]
Length = 1756
Score = 43.1 bits (100), Expect = 0.002
Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 18/172 (10%)
Query: 767 YSISPSFTKQGNNSKPSNHVSEPGN----IVSNKEVASLTVENNAFS---CDPGYVEKSP 819
YS SP++ Q +N G+ S KE S+ V + F +PG EK
Sbjct: 870 YSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKS 929
Query: 820 SFCCNEQETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFG 875
F+ +S + GR + + S F D+ K+ + + DP+ G
Sbjct: 930 EKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFG--KKDPNFKG 987
Query: 876 VSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVL 927
S GE F+S+ K++ + N +G+ + D K E SDD+ PV+
Sbjct: 988 FSGAGEKLFSSQCGKMANKANTSGDFEKDDD-----ACKTEDSDDIHFEPVV 1034
>gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo
sapiens]
Length = 1013
Score = 43.1 bits (100), Expect = 0.002
Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 18/172 (10%)
Query: 767 YSISPSFTKQGNNSKPSNHVSEPGN----IVSNKEVASLTVENNAFS---CDPGYVEKSP 819
YS SP++ Q +N G+ S KE S+ V + F +PG EK
Sbjct: 127 YSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKS 186
Query: 820 SFCCNEQETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFG 875
F+ +S + GR + + S F D+ K+ + + DP+ G
Sbjct: 187 EKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFG--KKDPNFKG 244
Query: 876 VSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVL 927
S GE F+S+ K++ + N +G+ + D K E SDD+ PV+
Sbjct: 245 FSGAGEKLFSSQCGKMANKANTSGDFEKDDD-----ACKTEDSDDIHFEPVV 291
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 43.1 bits (100), Expect = 0.002
Identities = 83/400 (20%), Positives = 149/400 (37%), Gaps = 58/400 (14%)
Query: 100 LEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQ---- 155
LE + E ++ ++ TKEK E + + + D ++KES S + + +
Sbjct: 697 LEKKSKLEKNIKDDKSTKEKHVSKERNFKEER---DKIKKESEKSFREEKIKDLKEEREN 753
Query: 156 ----------SLGKESIIEGIKRRIRNKKLKSLENPPLKITEN----EATQNIKVEFQDE 201
SLG +I E I + K++ +E I E+ E IK + ++
Sbjct: 754 IPTDKDSEFTSLGMSAIEESIGLHLVEKEI-DIEKQEKHIKESKEKPEKRSQIKEKDIEK 812
Query: 202 LYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSK 261
+ + T + I L L +C +++ L C E K
Sbjct: 813 MERKTFEKEKKIKHEHKSEKDKLDLSEC-----VDKIKEKDKLYSHHTEKCHKEGE---K 864
Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPE-ESDLYQSKTNGLLSCLQHEKNKYS 320
+N ++ + D + + + + K PE E L +SK L+ + +
Sbjct: 865 SKNTAAIKKTDDREKSREKMDRKHD-----KEKPEKERHLAESKEKHLMEKKNKQSDNSE 919
Query: 321 IEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNV 380
+S G+ K +L +K E + N N + ++ I DG +A+ + PL++
Sbjct: 920 YSKSEKGKNKEKDRELDKK--EKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSL 977
Query: 381 LRKVSHNTVSLMDHLLSVPETVEKETSS---------EHHVNAVFQKTIEPLLKEETENA 431
K D L P+ EK+ + H + + I LLK ++E A
Sbjct: 978 KEKTK-------DEPLKTPDGKEKDKKDKDIDRYKERDKHKDKI---QINSLLKLKSE-A 1026
Query: 432 SEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDL 471
+P S ASK+ K + + ER S +DL
Sbjct: 1027 DKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDL 1066
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 43.1 bits (100), Expect = 0.002
Identities = 83/400 (20%), Positives = 149/400 (37%), Gaps = 58/400 (14%)
Query: 100 LEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQ---- 155
LE + E ++ ++ TKEK E + + + D ++KES S + + +
Sbjct: 720 LEKKSKLEKNIKDDKSTKEKHVSKERNFKEER---DKIKKESEKSFREEKIKDLKEEREN 776
Query: 156 ----------SLGKESIIEGIKRRIRNKKLKSLENPPLKITEN----EATQNIKVEFQDE 201
SLG +I E I + K++ +E I E+ E IK + ++
Sbjct: 777 IPTDKDSEFTSLGMSAIEESIGLHLVEKEI-DIEKQEKHIKESKEKPEKRSQIKEKDIEK 835
Query: 202 LYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSK 261
+ + T + I L L +C +++ L C E K
Sbjct: 836 MERKTFEKEKKIKHEHKSEKDKLDLSEC-----VDKIKEKDKLYSHHTEKCHKEGE---K 887
Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPE-ESDLYQSKTNGLLSCLQHEKNKYS 320
+N ++ + D + + + + K PE E L +SK L+ + +
Sbjct: 888 SKNTAAIKKTDDREKSREKMDRKHD-----KEKPEKERHLAESKEKHLMEKKNKQSDNSE 942
Query: 321 IEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNV 380
+S G+ K +L +K E + N N + ++ I DG +A+ + PL++
Sbjct: 943 YSKSEKGKNKEKDRELDKK--EKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSL 1000
Query: 381 LRKVSHNTVSLMDHLLSVPETVEKETSS---------EHHVNAVFQKTIEPLLKEETENA 431
K D L P+ EK+ + H + + I LLK ++E A
Sbjct: 1001 KEKTK-------DEPLKTPDGKEKDKKDKDIDRYKERDKHKDKI---QINSLLKLKSE-A 1049
Query: 432 SEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDL 471
+P S ASK+ K + + ER S +DL
Sbjct: 1050 DKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDL 1089
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 42.7 bits (99), Expect = 0.003
Identities = 106/560 (18%), Positives = 221/560 (39%), Gaps = 83/560 (14%)
Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEE---SDLYQSKTNGL---------L 309
++ L SL + + + +TEEN + KL E ++ Q+K N +
Sbjct: 864 QKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAV 923
Query: 310 SCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTE----MNFSNEYNKSELMLQENQM 365
CLQ+EK++ +E ++ +K +++ E V E ++ N+ K +L+ E Q
Sbjct: 924 ICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVEND-EKLQLLRAELQS 982
Query: 366 IADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLK 425
+ E + L V R + + DH +S+ E ++KE ++ +N + + E + +
Sbjct: 983 LEQSHLKELEDTLQV-RHIQEFEKVMTDHRVSLEE-LKKE--NQQIINQIQESHAEIIQE 1038
Query: 426 EETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIE---RRSSREDLRSASEELKLSC 482
+E + ++ K S + + + +E + + ++++ EE +
Sbjct: 1039 KEKQ-------------LQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQ 1085
Query: 483 QRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLT 542
+ T+ K+ L + + LR Q ++ Q L
Sbjct: 1086 KETL----------------------KSLLEQETENLRTEISKLNQKIQDNNENYQVGLA 1123
Query: 543 DSKLLLQSSLTETNTESSSKEKLDSN--SNCLSSVSAVEPTLMVI----KEPIIKDDKKI 596
+ + L+ + +E S+ + +SN L+ V+++ I KE II+ K+
Sbjct: 1124 ELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKL 1183
Query: 597 KSE--ELSRRGSEVISNTTEDTQ-----LTSETQSLTGNKKKARGNLT-KLNLTATSKDG 648
SE L R+ E I+ E + L + Q L ++++ R L KLN +
Sbjct: 1184 DSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNC-----EK 1238
Query: 649 QEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSE 708
EA +A K + + ++ + + VK L K P + + + A+ E
Sbjct: 1239 DEAIQTALKEFKLEREVVEKELL--EKVKHLENQIA---KSPAIDSTRGDSSSLVAELQE 1293
Query: 709 REAYSPLELLDNLSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYS 768
+ + L+ L + R+N +NV ++ Q + +T + ++ N S
Sbjct: 1294 KLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1353
Query: 769 ISPSFTKQGNNSKPSNHVSE 788
+ + +Q + +SE
Sbjct: 1354 LKSTMQQQERDKDLIESLSE 1373
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 42.7 bits (99), Expect = 0.003
Identities = 106/560 (18%), Positives = 221/560 (39%), Gaps = 83/560 (14%)
Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEE---SDLYQSKTNGL---------L 309
++ L SL + + + +TEEN + KL E ++ Q+K N +
Sbjct: 864 QKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAV 923
Query: 310 SCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTE----MNFSNEYNKSELMLQENQM 365
CLQ+EK++ +E ++ +K +++ E V E ++ N+ K +L+ E Q
Sbjct: 924 ICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVEND-EKLQLLRAELQS 982
Query: 366 IADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLK 425
+ E + L V R + + DH +S+ E ++KE ++ +N + + E + +
Sbjct: 983 LEQSHLKELEDTLQV-RHIQEFEKVMTDHRVSLEE-LKKE--NQQIINQIQESHAEIIQE 1038
Query: 426 EETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIE---RRSSREDLRSASEELKLSC 482
+E + ++ K S + + + +E + + ++++ EE +
Sbjct: 1039 KEKQ-------------LQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQ 1085
Query: 483 QRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLT 542
+ T+ K+ L + + LR Q ++ Q L
Sbjct: 1086 KETL----------------------KSLLEQETENLRTEISKLNQKIQDNNENYQVGLA 1123
Query: 543 DSKLLLQSSLTETNTESSSKEKLDSN--SNCLSSVSAVEPTLMVI----KEPIIKDDKKI 596
+ + L+ + +E S+ + +SN L+ V+++ I KE II+ K+
Sbjct: 1124 ELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKL 1183
Query: 597 KSE--ELSRRGSEVISNTTEDTQ-----LTSETQSLTGNKKKARGNLT-KLNLTATSKDG 648
SE L R+ E I+ E + L + Q L ++++ R L KLN +
Sbjct: 1184 DSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNC-----EK 1238
Query: 649 QEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSE 708
EA +A K + + ++ + + VK L K P + + + A+ E
Sbjct: 1239 DEAIQTALKEFKLEREVVEKELL--EKVKHLENQIA---KSPAIDSTRGDSSSLVAELQE 1293
Query: 709 REAYSPLELLDNLSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYS 768
+ + L+ L + R+N +NV ++ Q + +T + ++ N S
Sbjct: 1294 KLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1353
Query: 769 ISPSFTKQGNNSKPSNHVSE 788
+ + +Q + +SE
Sbjct: 1354 LKSTMQQQERDKDLIESLSE 1373
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 41.6 bits (96), Expect = 0.007
Identities = 110/547 (20%), Positives = 215/547 (39%), Gaps = 90/547 (16%)
Query: 156 SLGKESIIEGIKRRI----RNKKLKSLENPPLKITENEATQNIK-VEFQDELYKNT-PKY 209
++ KE G + +I R + S E LK T + T+N++ VE + K T +
Sbjct: 1381 TMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEV 1440
Query: 210 SCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLA 269
S EVE V ++R + + +D + + + K+ N R
Sbjct: 1441 SQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCL 1500
Query: 270 EKSDTNSIPQLLQTEENVMG------VNKLLPEESDLYQ-------------------SK 304
E D N+ Q +Q + +NKL +E +L + ++
Sbjct: 1501 E--DENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITR 1558
Query: 305 TNGLLSCLQHEKNKYSIEESSVGRKPR----KRMKLSEKAD--------ETVTEMNFSNE 352
L LQ +K K E + + R KR KL E+ + + + N + +
Sbjct: 1559 FQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQ 1618
Query: 353 YNKSELM-------LQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKE 405
++ ++ L++ + + DG E + LR++S +L LL E+V++
Sbjct: 1619 LEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQ- 1677
Query: 406 TSSEHHVNAVFQKTIEPLLK---------EETENASEPLGYESMASKEDFKSMK---SFI 453
H N FQK IE + E ++ +E L E + +E+ ++++ +
Sbjct: 1678 ---AHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDL 1734
Query: 454 GKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASL- 512
+ +E ++ ++ +LRS +L++S RT+ + G I+ ++ +L
Sbjct: 1735 RRGRSEADSDKNATILELRS---QLQISNNRTLELQG----------LINDLQRERENLR 1781
Query: 513 PESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSK--EKLDSNSN 570
E F + + E+ ++ K+Q Q LL++ + E + + ++L+ +
Sbjct: 1782 QEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKS 1841
Query: 571 CLSSVSAVEPTLMVIKEPIIKD------DKKIKSEELSRRGSEVISNTTEDTQLTSETQS 624
L + + V+ L K+ I D K E + + SE + E L SE +
Sbjct: 1842 TLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIER 1901
Query: 625 LTGNKKK 631
L K+
Sbjct: 1902 LQAEIKR 1908
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.4 bits (93), Expect = 0.015
Identities = 78/386 (20%), Positives = 135/386 (34%), Gaps = 70/386 (18%)
Query: 260 SKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKY 319
+K++NL S E + QLLQ + +L QS NGL+ ++ K K
Sbjct: 2466 AKEQNLSSQVECLELEKA-QLLQGLDEAKNNYIVL-------QSSVNGLIQEVEDGKQKL 2517
Query: 320 SIEESSVGRKPRK---RMKLSEKADETVTEMNFSNEYN------------KSELMLQENQ 364
++ + R + + +L K + E E N K +++ +N
Sbjct: 2518 EKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNA 2577
Query: 365 MIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLL 424
+ D E S N+ ++ + M + V + KET + ++ + QKT E L
Sbjct: 2578 SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAE--L 2635
Query: 425 KEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQR 484
+EE L E E+ KS K + ++L + ELK S
Sbjct: 2636 QEELSGEKNRLAGELQLLLEEIKSSKDQL---------------KELTLENSELKKSLD- 2679
Query: 485 TIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDS 544
C K + + +E + + H+ + H
Sbjct: 2680 ---------------------CMHKDQVEKEGKV----REEIAEYQLRLHEAEKKH---Q 2711
Query: 545 KLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRR 604
LLL ++ + +EKL S CLSS +E L+ + + + K ++ L
Sbjct: 2712 ALLLDTNKQYEVEIQTYREKLTSKEECLSS-QKLEIDLLKSSKEELNNSLKATTQILEEL 2770
Query: 605 GSEVISNTTEDTQLTSETQSLTGNKK 630
+ N QL E + G K
Sbjct: 2771 KKTKMDNLKYVNQLKKENERAQGKMK 2796
Score = 38.5 bits (88), Expect = 0.056
Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 20/231 (8%)
Query: 257 ENFSKKEN--LRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKT----NGLLS 310
E F EN R +EK+ L+ + V+ KL E+ + + K LS
Sbjct: 1895 ERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELS 1954
Query: 311 CLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGK 370
+ E+N+ E ++ +K +LSEK E E+ E ++SE +
Sbjct: 1955 VVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQEL----ESHQSECL-----HCIQVA 2005
Query: 371 EAETKSPLNVLRKVSHNTVSLM---DHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEE 427
EAE K +L+ +S + L+ HL +++EK++ + + I L KE+
Sbjct: 2006 EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEK 2065
Query: 428 TENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEEL 478
E ++ S+ D++ + + K+ +E+ L S EE+
Sbjct: 2066 ELLVKESESLQARLSESDYEKLN--VSKALEAALVEKGEFALRLSSTQEEV 2114
Score = 37.4 bits (85), Expect = 0.12
Identities = 56/327 (17%), Positives = 133/327 (40%), Gaps = 24/327 (7%)
Query: 138 RKESLTSSESFQTV--ECLQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIK 195
++E SFQT+ EC+Q K + + +++ + E L + + N++
Sbjct: 397 QEELSRQQRSFQTLDQECIQM--KARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLE 454
Query: 196 VEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKG-------CNDENNLPYKP 248
EF+ +L + + + + S+ +++ N S C+ E L K
Sbjct: 455 -EFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAEL--KN 511
Query: 249 DGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSK--TN 306
C++ ++NF+++ ++ ++++ + + + +EN + + KL +DL + + +
Sbjct: 512 IKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQ 571
Query: 307 GLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMI 366
LL +H + + + S ++ + + E + E+ E EN+ +
Sbjct: 572 DLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEEL--KEEKTLFSCWKSENEKL 629
Query: 367 ADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSE---HHVNAVFQKTIEPL 423
E+E + N+ K++H L + E E+ + E +++ + L
Sbjct: 630 LTQMESEKE---NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686
Query: 424 LKEETENASEPLGYESMASKEDFKSMK 450
+ E ++ L Y + K +F K
Sbjct: 687 DSKSVEVETQKLAYMELQQKAEFSDQK 713
Score = 35.0 bits (79), Expect = 0.62
Identities = 60/290 (20%), Positives = 115/290 (39%), Gaps = 30/290 (10%)
Query: 321 IEESSVGRKPRKRMKLSE--KADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPL 378
+ +S V ++ KL E A + V S NK + E Q++ D E E ++ +
Sbjct: 873 MHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK----ELQLLNDKVETE-QAEI 927
Query: 379 NVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEE--TENASEPLG 436
L+K +H + L + ET+ E + ++ ++ IE L +E + + L
Sbjct: 928 QELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Query: 437 YESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTG------ 490
E M + +S ++I ER S +L ++ KL + TG
Sbjct: 988 QEKMNLIQKSESFANYID--------EREKSISELSDQYKQEKLILLQRCEETGNAYEDL 1039
Query: 491 --KRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLL 548
K +++ + SL E+ + E ++ +HQ T L ++
Sbjct: 1040 SQKYKAAQEKNSKLECLLNECTSLCENR---KNELEQLKEAFAKEHQEFLTKLAFAEERN 1096
Query: 549 QSSLTETNT--ESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKI 596
Q+ + E T ++ E D+ +N S ++ +M +KE K K++
Sbjct: 1097 QNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEV 1146
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 39.3 bits (90), Expect = 0.033
Identities = 74/405 (18%), Positives = 153/405 (37%), Gaps = 66/405 (16%)
Query: 275 NSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGL----------LSCLQHEKNKYSIEES 324
N QL TEE ++ ++ L S+ +S+ L + L+ EKN S + S
Sbjct: 715 NFTSQLKATEEKLLDLDALRKASSE-GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKAS 773
Query: 325 SVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEA-----ETKSPLN 379
S+ R+ + R E ++E++ E + EL + + + +EA + +N
Sbjct: 774 SITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVN 833
Query: 380 VLRKVSHNTVSLMDHLLSVPETV--------EKETSSEHHVNA--VFQKTIEPLLKEETE 429
L + L L + E + EK+ E + A + I ++K +
Sbjct: 834 KLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD 893
Query: 430 NASE--PLGYESMASKEDFKSMK----------SFIGKSPNEYHIERRSSREDLRSASEE 477
N+S+ + E + D + ++ SF+ KS + ++ S+++ EE
Sbjct: 894 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 953
Query: 478 LKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVP-KHQT 536
K +R + K+ + S C+++ + T
Sbjct: 954 EKKELERKLSDLEKK--------------------------METSHNQCQELKARYERAT 987
Query: 537 NQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKI 596
++T ++L T +TE K + NS L + + K +D
Sbjct: 988 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQ 1047
Query: 597 KSEELSRRGSEVISNTTEDTQLTSETQS-LTGNKKKARGNLTKLN 640
E++++ +E +++ + Q ++ Q+ L K+ N+ +LN
Sbjct: 1048 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1092
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 39.3 bits (90), Expect = 0.033
Identities = 74/405 (18%), Positives = 153/405 (37%), Gaps = 66/405 (16%)
Query: 275 NSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGL----------LSCLQHEKNKYSIEES 324
N QL TEE ++ ++ L S+ +S+ L + L+ EKN S + S
Sbjct: 750 NFTSQLKATEEKLLDLDALRKASSE-GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKAS 808
Query: 325 SVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEA-----ETKSPLN 379
S+ R+ + R E ++E++ E + EL + + + +EA + +N
Sbjct: 809 SITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVN 868
Query: 380 VLRKVSHNTVSLMDHLLSVPETV--------EKETSSEHHVNA--VFQKTIEPLLKEETE 429
L + L L + E + EK+ E + A + I ++K +
Sbjct: 869 KLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD 928
Query: 430 NASE--PLGYESMASKEDFKSMK----------SFIGKSPNEYHIERRSSREDLRSASEE 477
N+S+ + E + D + ++ SF+ KS + ++ S+++ EE
Sbjct: 929 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 988
Query: 478 LKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVP-KHQT 536
K +R + K+ + S C+++ + T
Sbjct: 989 EKKELERKLSDLEKK--------------------------METSHNQCQELKARYERAT 1022
Query: 537 NQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKI 596
++T ++L T +TE K + NS L + + K +D
Sbjct: 1023 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQ 1082
Query: 597 KSEELSRRGSEVISNTTEDTQLTSETQS-LTGNKKKARGNLTKLN 640
E++++ +E +++ + Q ++ Q+ L K+ N+ +LN
Sbjct: 1083 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1127
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 39.3 bits (90), Expect = 0.033
Identities = 64/324 (19%), Positives = 120/324 (37%), Gaps = 30/324 (9%)
Query: 337 SEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLL 396
S+ A+E N + NK E+M+ + + +E + RK+ T L D +
Sbjct: 1013 SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA 1072
Query: 397 SVPETVEK-----ETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKSMKS 451
+ +++ E A+ + E L K L + +EDF+S K+
Sbjct: 1073 ELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKA 1132
Query: 452 FIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARISAWCWKKAS 511
S N+ ++R E+L + EL+ + T RT A + K +
Sbjct: 1133 ----SRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL------KKA 1182
Query: 512 LPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNC 571
L E + + RQ +H T L S+ L Q+ + N E + + N
Sbjct: 1183 LEEETKNHEAQIQDMRQ----RHATALEEL--SEQLEQAKRFKANLEKNKQGLETDNKEL 1236
Query: 572 LSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKK 631
V ++ +K + + K ++L + E+ + +E +L E +
Sbjct: 1237 ACEVKVLQQ---------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN 1287
Query: 632 ARGNLTKLNLTATSKDGQEANNSA 655
N++ L A K + A ++A
Sbjct: 1288 ELDNVSTLLEEAEKKGIKFAKDAA 1311
Score = 37.4 bits (85), Expect = 0.12
Identities = 92/453 (20%), Positives = 182/453 (40%), Gaps = 68/453 (15%)
Query: 76 KAARRQVEGRRGPVSPSDSSDPRGLE-----AAKEAELPLQTERHTKEKRKVTEASSDDP 130
KA+R + E ++ +S + LE A + EL + E+ E +K E + +
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH 1190
Query: 131 QPGLDLVRKESLTSSESF---------------QTVECLQSLGKE-----SIIEGIKRRI 170
+ + +R+ T+ E + + L++ KE +++ +K
Sbjct: 1191 EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAES 1250
Query: 171 RNKKLK---SLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLR 227
+K+ K ++ K++E + ++VE ++ K L E++N S L L
Sbjct: 1251 EHKRKKLDAQVQELHAKVSEGD---RLRVELAEKASK---------LQNELDNVSTL-LE 1297
Query: 228 DCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEK--SDTNSIPQLLQTEE 285
+ K D +L + + E +K NL S + + NS+ + + EE
Sbjct: 1298 EAEK-KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEE 1356
Query: 286 NVMG--VNKLLPEESDLYQSKTN-----GLLSCLQHEKNKYSIEESSVGRKPRKRMKLSE 338
++L +S L +K G + L+ K K + ++ ++ ++ +
Sbjct: 1357 EARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYD 1416
Query: 339 KADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVL---RKVSHNTVSLMDHL 395
K ++T + E + + L + +A E + K +L + +S D
Sbjct: 1417 KLEKTKNRLQ--QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDR- 1473
Query: 396 LSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKSMKSFIGK 455
+ E EKET + A+ ++ +E KEE E ++ L A ED S K +GK
Sbjct: 1474 -AEAEAREKETKALSLARAL-EEALEA--KEEFERQNKQL----RADMEDLMSSKDDVGK 1525
Query: 456 SPNEYHIERRSSR---EDLRSASEELKLSCQRT 485
+ +E +R+ E++R+ EEL+ Q T
Sbjct: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 38.9 bits (89), Expect = 0.043
Identities = 146/704 (20%), Positives = 280/704 (39%), Gaps = 118/704 (16%)
Query: 98 RGLEAAKEAELPL-QTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQS 156
R +E+ K A + + Q + KE E+ + + GL+L++ SF+ E L
Sbjct: 708 RNVESLKCASMKMAQLQLENKE----LESEKEQLKKGLELLKA-------SFKKTERL-- 754
Query: 157 LGKESIIEGIKRRIRNKKL-KSLENPPLKITENEAT-QNIKVEFQDELYKNTP--KYSCN 212
E +G+ I N++L K+LEN KI + E+ Q++++E Q L KN K S
Sbjct: 755 ---EVSYQGLD--IENQRLQKTLENSNKKIQQLESELQDLEMENQT-LQKNLEELKISSK 808
Query: 213 ILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKS 272
L + N L+ K EN + LR AE
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKEN--------------------KRLRQQAEIK 848
Query: 273 DTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLL--SCLQ----HEKNKYSIEESSV 326
DT EEN + + L E L SK G+ SC++ ++NK ++ +++
Sbjct: 849 DTT-------LEENNVKIGNLEKENKTL--SKEIGIYKESCVRLKELEKENKELVKRATI 899
Query: 327 GRKPRKRMKLSEKADETVTEMNFSNEYNK-----------SELMLQENQMIADGK----E 371
K ++ + E + +N+ K E +L + Q D + E
Sbjct: 900 DIKTLVTLR-EDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE 958
Query: 372 AETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETEN- 430
++ +S L ++ ++ ++ L ++ E +K E L + + E
Sbjct: 959 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT---VKKNYEALKQRQDEER 1015
Query: 431 ---ASEPL-GYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTI 486
+S P+ G ++ +E ++ + + +ER ++ L++ + LK ++
Sbjct: 1016 MVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT--LQAEKQALKTQLKQLE 1073
Query: 487 PMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTD--S 544
A+I A + SL E + L+ +Q + QV+ + T L + +
Sbjct: 1074 TQNNNLQ------AQILALQRQTVSLQEQNTTLQ-TQNAKLQVENSTLNSQSTSLMNQNA 1126
Query: 545 KLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIK------EPIIKDDKKIKS 598
+LL+Q S E ES KE+ D S S + E ++ + E +I +KS
Sbjct: 1127 QLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKS 1186
Query: 599 EELSRRGSEVISNTTED--TQLTSETQSLTGNKKKARGNLTKL-----NLTATSKDGQEA 651
+ + EV ED QL + L +K + K+ N + + ++
Sbjct: 1187 ---AHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKL 1243
Query: 652 NNSAGKTIHRKACIAQQTFIV----PDLVKILNTGRLTNFKIPLLKNK-SEKRKEVNAKS 706
+ H + + ++T ++ +L +LN +L ++ +K E+ ++++ S
Sbjct: 1244 CGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITS 1303
Query: 707 SEREAYSPLELLDNLSGADVRQNRS-KENVSMMMLGPQTLSIRN 749
++ + ELL L G +NR + + +ML +TL +N
Sbjct: 1304 TKLN--NQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1345
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 38.5 bits (88), Expect = 0.056
Identities = 47/189 (24%), Positives = 75/189 (39%), Gaps = 6/189 (3%)
Query: 294 LPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRM---KLSEKADET-VTEMNF 349
L EE L L+ CL+ EK++ + + +V + + EK ET +M
Sbjct: 222 LIEELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEH 281
Query: 350 SNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSE 409
E N E +Q + KE E + K L L S + VE+ S
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 410 HHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKS--MKSFIGKSPNEYHIERRSS 467
++A F K E L K +T+ YE+ S ++ S ++S E H RRS
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSI 401
Query: 468 REDLRSASE 476
++ + S+
Sbjct: 402 KKITQELSD 410
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 38.5 bits (88), Expect = 0.056
Identities = 47/189 (24%), Positives = 75/189 (39%), Gaps = 6/189 (3%)
Query: 294 LPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRM---KLSEKADET-VTEMNF 349
L EE L L+ CL+ EK++ + + +V + + EK ET +M
Sbjct: 222 LIEELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEH 281
Query: 350 SNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSE 409
E N E +Q + KE E + K L L S + VE+ S
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 410 HHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKS--MKSFIGKSPNEYHIERRSS 467
++A F K E L K +T+ YE+ S ++ S ++S E H RRS
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSI 401
Query: 468 REDLRSASE 476
++ + S+
Sbjct: 402 KKITQELSD 410
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 38.5 bits (88), Expect = 0.056
Identities = 29/96 (30%), Positives = 53/96 (55%), Gaps = 5/96 (5%)
Query: 111 QTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTV-ECLQSLGKESIIEGIKRR 169
+ ER + K+++ +A++ LDL+++E + F ++ E Q L KE++ E K +
Sbjct: 315 EVERLQQLKKELEKATAS----ALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLK 370
Query: 170 IRNKKLKSLENPPLKITENEATQNIKVEFQDELYKN 205
R +KL + ++ENE T+NIK++ Q KN
Sbjct: 371 SRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKN 406
>gi|156139122 CXXC finger 6 [Homo sapiens]
Length = 2136
Score = 38.1 bits (87), Expect = 0.073
Identities = 102/530 (19%), Positives = 200/530 (37%), Gaps = 73/530 (13%)
Query: 237 GCNDENNLPYKPDGGCMHVAENFSKKENLRS--LAEKSDTNSIPQLLQTEE-----NVMG 289
G +E L P H EN +K E+ + EK N QL + NV
Sbjct: 678 GHGEEQKLELNP-----HTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPE 732
Query: 290 VNKLLPEESDLYQSKT---------NGL--LSCLQHEKN----KYSIEESSVGRKPRKRM 334
K E D ++K+ NG+ + CL E N K++IEE +
Sbjct: 733 AEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYK 792
Query: 335 KLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDH 394
L + A+ + + + + L + N ++ S + H++ S+++H
Sbjct: 793 FLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSS-------IPHSSHSIINH 845
Query: 395 LLSV------PETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKS 448
S+ P+T E S E + Q ++ L+K+ + + E++ + S
Sbjct: 846 HASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPS 905
Query: 449 MKSFIGKSPNEYHIERRSS-------------REDLRSASEELKLSCQRTIPMTGKRTWP 495
S KS + E+R++ R+DL+ + + + P K++
Sbjct: 906 ENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQS-- 963
Query: 496 YYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTET 555
SC + + + +L S + Q H+ ++ + S + +S+ ++
Sbjct: 964 --SCNTV-VFNGQTTTLSNSHI-----NSATNQASTKSHEYSKVTNSLSLFIPKSNSSKI 1015
Query: 556 NTESSSKEKLDSNSNCLSSVSAVEPTLMVIK--EPIIKDDKKIKSEELSRRGSEVISNTT 613
+T S + + + NC + + + P ++ ++ KK+ S++LS + + +
Sbjct: 1016 DTNKSIAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDA-THTQIE 1074
Query: 614 ED--TQLTSETQSLTGNKKKARGNLTKLNLTATSK---DGQEANNSAGKTIHRKACIAQQ 668
ED TQLT + N K K+ T TS + Q+ N TI +K +
Sbjct: 1075 EDVATQLTQLASIIKINYIKPEDK--KVESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVH 1132
Query: 669 TFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELL 718
L K N + P + +K V+ + ++R+ + L +
Sbjct: 1133 NNHGSSLTKQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYM 1182
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 38.1 bits (87), Expect = 0.073
Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 29/172 (16%)
Query: 21 NLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGRGEVESDKSVAASGAGKAARR 80
+LQ+ QAP P AA C + K++ PG+ E E + A
Sbjct: 523 SLQREQAPSPPAA---------CEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSP 573
Query: 81 QVEGRRGPVSPSDSSDPRGLEAAKE--AELPLQTERHTKEKRKVTEASSDDPQPGLDLVR 138
+V PV+P + L+A +E A++ Q +RH E + Q + +R
Sbjct: 574 EVRSTE-PVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESK----------QEKMQQLR 622
Query: 139 KESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEA 190
E L E + + Q KE + ++ R++ K++E ++ E E+
Sbjct: 623 -EKLCQEEEEEILRLHQQ--KEQSLSSLRERLQ----KAIEEEEARMREEES 667
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 37.7 bits (86), Expect = 0.095
Identities = 144/700 (20%), Positives = 284/700 (40%), Gaps = 111/700 (15%)
Query: 98 RGLEAAKEAELPL-QTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQS 156
R +E+ K A + + Q + KE E+ + + GL+L++ SF+ E L
Sbjct: 708 RNVESLKCASMKMAQLQLENKE----LESEKEQLKKGLELLKA-------SFKKTERL-- 754
Query: 157 LGKESIIEGIKRRIRNKKL-KSLENPPLKITENEAT-QNIKVEFQDELYKNTP--KYSCN 212
E +G+ I N++L K+LEN KI + E+ Q++++E Q L KN K S
Sbjct: 755 ---EVSYQGLD--IENQRLQKTLENSNKKIQQLESELQDLEMENQT-LQKNLEELKISSK 808
Query: 213 ILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKS 272
L + N L+ K EN + LR AE
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKEN--------------------KRLRQQAEIK 848
Query: 273 DTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLL--SCLQ----HEKNKYSIEESSV 326
DT EEN + + L E L SK G+ SC++ ++NK ++ +++
Sbjct: 849 DTT-------LEENNVKIGNLEKENKTL--SKEIGIYKESCVRLKELEKENKELVKRATI 899
Query: 327 GRKPRKRMKLSEKADETVTEMNFSNEYNK-----SELMLQENQMIADGKEAETKSPL--N 379
K ++ + E + +N+ K ++ L + +++ D + + + L +
Sbjct: 900 DIKTLVTLR-EDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLES 958
Query: 380 VLRKVSHNTVSLMDHLLSVPET-VEKETSSEHHVNA---VFQKTIEPLLKEETEN----A 431
L ++ + + ++ E +E+ T+ + +K E L + + E +
Sbjct: 959 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQS 1018
Query: 432 SEPL-GYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTG 490
S P+ G ++ +E ++ + + +ER ++ L++ + LK ++
Sbjct: 1019 SPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT--LQAEKQALKTQLKQLETQNN 1076
Query: 491 KRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTD--SKLLL 548
A+I A + SL E + L+ +Q + QV+ + T L + ++LL+
Sbjct: 1077 NLQ------AQILALQRQTVSLQEQNTTLQ-TQNAKLQVENSTLNSQSTSLMNQNAQLLI 1129
Query: 549 QSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIK------EPIIKDDKKIKSEELS 602
Q S E ES KE+ D S S + E ++ + E +I +KS +
Sbjct: 1130 QQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKS---A 1186
Query: 603 RRGSEVISNTTED--TQLTSETQSLTGNKKKARGNLTKL-----NLTATSKDGQEANNSA 655
+ EV ED QL + L +K + K+ N + + ++
Sbjct: 1187 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 1246
Query: 656 GKTIHRKACIAQQTFIV----PDLVKILNTGRLTNFKIPLLKNK-SEKRKEVNAKSSERE 710
+ H + + ++T ++ +L +LN +L ++ +K E+ ++++ S++
Sbjct: 1247 DRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306
Query: 711 AYSPLELLDNLSGADVRQNRS-KENVSMMMLGPQTLSIRN 749
+ ELL L G +NR + + +ML +TL +N
Sbjct: 1307 --NQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1344
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 37.4 bits (85), Expect = 0.12
Identities = 58/221 (26%), Positives = 84/221 (38%), Gaps = 52/221 (23%)
Query: 853 ILKAYEDDVLLIDVIQDD------PDLFGVSNEGELSFTSEVPKI----------SQEPN 896
+LKA D VLL + Q D P L + E E PK S+E
Sbjct: 204 LLKAQIDPVLLKNSSQQDNSSRESPSL----EDEETKKEEETPKQEEQKESEKMKSEEQP 259
Query: 897 VAGEHQSTDSKYMETPVKKEPSD--DLRELPVL------------------DCGWIKPDI 936
+ E++ST + ET VKKE D +L +LPV+ + K ++
Sbjct: 260 MDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFKENV 319
Query: 937 CASNSAESEIKRDPKDVNTSLGE-VANETSENETLGDFSEQIKGSDLDEKHRFTDKVITK 995
E + DPKD +S+ + VA E E G ++ H T+K +
Sbjct: 320 KPIKVEVKECRADPKDTKSSMEKPVAQEPERIEF---------GGNIKSSHEITEK--ST 368
Query: 996 EEKENIYEVCKSKDSRNADFMVGECQFAVPVPKPLCLLVPP 1036
EE E + ++K + F PV PLC V P
Sbjct: 369 EETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGPLCKSVTP 409
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 37.4 bits (85), Expect = 0.12
Identities = 79/431 (18%), Positives = 164/431 (38%), Gaps = 55/431 (12%)
Query: 98 RGLEAAKEAELPLQTERHTK-EKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQS 156
R E +K+ E+ + T+ + +K +EA Q L +E + F+T+
Sbjct: 766 RATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQK-LTKQEEEKQILKQDFETLSQETK 824
Query: 157 LGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSP 216
+ E + I+ + + +E L +TE ++ + D L + ++
Sbjct: 825 IQHEELNNRIQTTVTELQKVKMEKEAL-MTELSTVKDKLSKVSDSLKNSKSEF------- 876
Query: 217 EVENN----SVLKL-RDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEK 271
E EN ++L L + C H EN L + + + +KE S K
Sbjct: 877 EKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKE------LKKSLEKEKEASHQLK 930
Query: 272 SDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPR 331
+ NS+ + L +N + N+ +E Q N L + +K + + +
Sbjct: 931 LELNSMQEQLIQAQNTLKQNE---KEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVL 987
Query: 332 KRMKLSEKADETVTEMN------------FSNEYNKSELMLQENQMIADGKEAETKSPLN 379
++ +L K + +T+ N Y KS+ ++ Q G+E+E +
Sbjct: 988 QKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQ 1047
Query: 380 VLRKVSH-----------------NTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEP 422
L+ V N L+ L + T+E++++ + K ++
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQD 1107
Query: 423 LLKEETENASEPLGYES-MASKEDFK-SMKSFIGKSPNEYHIERRSSREDLRSASEELKL 480
+ KE++ E + +S +A E+ K + I K E + S +++ + + +L
Sbjct: 1108 IQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQL 1167
Query: 481 SCQRTIPMTGK 491
Q+ + + GK
Sbjct: 1168 LIQQKLELQGK 1178
Score = 33.5 bits (75), Expect = 1.8
Identities = 104/502 (20%), Positives = 192/502 (38%), Gaps = 90/502 (17%)
Query: 257 ENFSKKENLRSLAEKSD---TNSIPQLLQTE---ENVMGVNKLLPEESDLYQSKTNGLLS 310
+ K + L+ K D T+S +L E E N + + DL++ K L +
Sbjct: 111 KELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLAT 170
Query: 311 CLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGK 370
+ K+KY E S L E A++ VT + + E NK ++Q+ + +
Sbjct: 171 EIADIKSKYDEERS-----------LREAAEQKVTRL--TEELNKEATVIQD--LKTELL 215
Query: 371 EAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETEN 430
+ + VL+K +LMD++ T+E+E SE LK+E +
Sbjct: 216 QRPGIEDVAVLKKELVQVQTLMDNM-----TLERERESEK-------------LKDECKK 257
Query: 431 ASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTG 490
L + +S+ ++S + K P E + + ++ L+S+ EL Q
Sbjct: 258 ----LQSQYASSEATISQLRSELAKGPQEVAVYVQELQK-LKSSVNELTQKNQTLTENLL 312
Query: 491 KRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQS 550
K+ Y + E S + Q + Q D+ Q Q+ L+ S ++
Sbjct: 313 KKEQDYTKL---------EEKHNEESVSKKNIQATLHQKDLDCQQL-QSRLSAS----ET 358
Query: 551 SLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRRGSEVIS 610
SL + E S EK ++ +S VE +K + + EE + G ++ S
Sbjct: 359 SLHRIHVELS--EKGEATQKLKEELSEVETKYQHLKAEF--KQLQQQREEKEQHGLQLQS 414
Query: 611 NTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIHRKACIAQQTF 670
+ ET+ G +A G L ++ S+ K + ++ +A
Sbjct: 415 EINQLHSKLLETERQLG---EAHGRLK-----------EQRQLSSEKLMDKEQQVADLQL 460
Query: 671 IVPDLVKIL--NTGRLTNFKIPLLKNKSEKRKEVNAKSSE----REAYSPLELL------ 718
+ L + L T + L K K + +++ + S REA + LE +
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGD 520
Query: 719 --DNLSGADVRQNRSKENVSMM 738
+ + +SKEN+S++
Sbjct: 521 KDQKIQNLEALLQKSKENISLL 542
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 37.4 bits (85), Expect = 0.12
Identities = 46/227 (20%), Positives = 90/227 (39%), Gaps = 25/227 (11%)
Query: 265 LRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEES 324
LRS + D Q+L+ E+ V N+ + + Y+ + L S L+ E + + S
Sbjct: 304 LRSKTQSLDEEQKQQILELEKKV---NEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHS 360
Query: 325 SVGRKPRKRMKLSEKA-------DETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSP 377
+ + ++ +A D+ +M+ ++NK +L L+E++ + + E ++
Sbjct: 361 KTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDK---NQLQQELENL 417
Query: 378 LNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGY 437
VL + + HL + E+ S + A Q ++ E L
Sbjct: 418 KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQ------------DSQERLQN 465
Query: 438 ESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQR 484
E +K+ K K + E ER+ E + + EE KL +
Sbjct: 466 ELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDK 512
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 37.4 bits (85), Expect = 0.12
Identities = 46/227 (20%), Positives = 90/227 (39%), Gaps = 25/227 (11%)
Query: 265 LRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEES 324
LRS + D Q+L+ E+ V N+ + + Y+ + L S L+ E + + S
Sbjct: 424 LRSKTQSLDEEQKQQILELEKKV---NEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHS 480
Query: 325 SVGRKPRKRMKLSEKA-------DETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSP 377
+ + ++ +A D+ +M+ ++NK +L L+E++ + + E ++
Sbjct: 481 KTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDK---NQLQQELENL 537
Query: 378 LNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGY 437
VL + + HL + E+ S + A Q ++ E L
Sbjct: 538 KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQ------------DSQERLQN 585
Query: 438 ESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQR 484
E +K+ K K + E ER+ E + + EE KL +
Sbjct: 586 ELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDK 632
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 37.4 bits (85), Expect = 0.12
Identities = 72/364 (19%), Positives = 135/364 (37%), Gaps = 43/364 (11%)
Query: 263 ENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIE 322
E R+ E+ +L + +E V+ + EE +++ + + E +
Sbjct: 1326 ERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKL 1385
Query: 323 ESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLR 382
+ + R R+R +L + +E E E + LQ+ + +EAE + + +
Sbjct: 1386 RAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445
Query: 383 KV--SHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESM 440
KV + +H L + + E H + + +E L ++ E
Sbjct: 1446 KVVLQQDPQQAREHAL-----LRLQLEEEQHRRQLLEGELETLRRKLA-------ALEKA 1493
Query: 441 ASKEDFKSMKSF-IGKSPNEYHIER-RSSREDLRSASEELKLSCQRTIPMTGKRTWPYYS 498
KE +S + K E I+R +SS E+ + EL + R
Sbjct: 1494 EVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLE------------ 1541
Query: 499 CARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTE 558
AR+S + + + FLR K Q + +L LQS + TE
Sbjct: 1542 -ARLSELEFHNSKSSKELDFLREENH--------KLQLERQNLQLETRRLQSEINMAATE 1592
Query: 559 SSSKEKL---DSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRR-GSEVISNTTE 614
+ + DS +N S + ++E L +K + DK ++ +EL +R GS +
Sbjct: 1593 TRDLRNMTVADSGTNHDSRLWSLERELDDLKR--LSKDKDLEIDELQKRLGSVAVKREQR 1650
Query: 615 DTQL 618
+ L
Sbjct: 1651 ENHL 1654
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 37.0 bits (84), Expect = 0.16
Identities = 85/420 (20%), Positives = 157/420 (37%), Gaps = 56/420 (13%)
Query: 99 GLEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLG 158
G E + E P T +RK+T+ + + L L K L E + G
Sbjct: 1980 GKETLSKGETP-----ETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKG 2034
Query: 159 KESIIEGIKRRIRN-KKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPE 217
K G + ++ +KL +K E+ + + K+ +++ K K + +
Sbjct: 2035 KLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKL---NKILKALQKLTRDERKLT 2091
Query: 218 VENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSI 277
E + K++ + +++ L K + +K E + ++ N +
Sbjct: 2092 QEEIKMTKMKRALFVKERRLSIEQSKLDIK-EWDFSEKRSELTKDEKKLARKQRKLANKM 2150
Query: 278 PQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSV----------- 326
+++ EE K+ EES L + + +L ++ + IEE V
Sbjct: 2151 RRMINKEE------KMTEEESKLARKHSEVILD----DEEEGGIEEEEVIPFLKRRWRKR 2200
Query: 327 -----GRKPRKRMKLSEKADETVTEMNFSNEYNK--SELMLQENQMIADGKEAETKSPLN 379
G KP++ K S + DE +E +FS E EL QE+ + +E E +
Sbjct: 2201 KEAKRGDKPKE--KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 380 VLRKVSHNTVSLMDHLLSVPETVEKETSSE------------HHVNAVFQKTIEPLLKEE 427
+V + + VEKE + VF++ E + +EE
Sbjct: 2259 E-EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE 2317
Query: 428 TENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIP 487
TE+ S+ E S E+ + I K ++ ++ + R+ LR E LS R +P
Sbjct: 2318 TESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ-RRKSLR--GRERVLSILRGVP 2374
Score = 31.6 bits (70), Expect = 6.8
Identities = 20/83 (24%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 586 KEPIIKDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATS 645
+E ++++DKK+K EE + ++S+ +++ Q E + + G + +T
Sbjct: 1506 EEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQ 1565
Query: 646 KDGQEANNSAGKTIHRKACIAQQ 668
+ QE + A IHRK A++
Sbjct: 1566 RHIQEEHKWA--RIHRKRARAEK 1586
>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 37.0 bits (84), Expect = 0.16
Identities = 52/263 (19%), Positives = 95/263 (36%), Gaps = 40/263 (15%)
Query: 531 VPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPII 590
+ + + + T S S +T + T S+S S S+ +S + ++ + I
Sbjct: 110 ITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSI 169
Query: 591 KDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQE 650
I S S + SN+T T ++ T + T T T+T+
Sbjct: 170 SSS--ITSTSTSTTSTS--SNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTT 225
Query: 651 ANNSAGK------TIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNA 704
+ +++ T H+K C A + + L +++TG K R V
Sbjct: 226 STSTSATSSIRKLTPHQKQCGALASAFLFGLSLLVSTG-----------TKGLGRSLVTP 274
Query: 705 KSSEREAYSPLELLDNLSGA----DVRQNRSKENVSMMMLG---------------PQTL 745
+ S +P + A + RQ R + V+ G PQ L
Sbjct: 275 RPSPPPPLTPQAESGGVDAAPRAPETRQVRKVDGVNPAAAGPRGGATACSGVQSRRPQGL 334
Query: 746 SIRNSVTPVQASSDSFYNKKSYS 768
++R ++ P + S+D +N S S
Sbjct: 335 ALRATLLPAKRSADMRWNSGSCS 357
>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 37.0 bits (84), Expect = 0.16
Identities = 52/263 (19%), Positives = 95/263 (36%), Gaps = 40/263 (15%)
Query: 531 VPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPII 590
+ + + + T S S +T + T S+S S S+ +S + ++ + I
Sbjct: 110 ITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSI 169
Query: 591 KDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQE 650
I S S + SN+T T ++ T + T T T+T+
Sbjct: 170 SSS--ITSTSTSTTSTS--SNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTT 225
Query: 651 ANNSAGK------TIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNA 704
+ +++ T H+K C A + + L +++TG K R V
Sbjct: 226 STSTSATSSIRKLTPHQKQCGALASAFLFGLSLLVSTG-----------TKGLGRSLVTP 274
Query: 705 KSSEREAYSPLELLDNLSGA----DVRQNRSKENVSMMMLG---------------PQTL 745
+ S +P + A + RQ R + V+ G PQ L
Sbjct: 275 RPSPPPPLTPQAESGGVDAAPRAPETRQVRKVDGVNPAAAGPRGGATACSGVQSRRPQGL 334
Query: 746 SIRNSVTPVQASSDSFYNKKSYS 768
++R ++ P + S+D +N S S
Sbjct: 335 ALRATLLPAKRSADMRWNSGSCS 357
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,432,351
Number of Sequences: 37866
Number of extensions: 2990163
Number of successful extensions: 9323
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 8919
Number of HSP's gapped (non-prelim): 618
length of query: 1692
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1576
effective length of database: 13,855,062
effective search space: 21835577712
effective search space used: 21835577712
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.