BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|222537754 hypothetical protein LOC375337 [Homo sapiens] (1692 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|222537754 hypothetical protein LOC375337 [Homo sapiens] 3381 0.0 gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi... 47 2e-04 gi|147903302 MAP7 domain containing 3 [Homo sapiens] 47 2e-04 gi|150418007 RAN binding protein 2 [Homo sapiens] 45 6e-04 gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi... 43 0.002 gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapi... 43 0.002 gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 43 0.002 gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 43 0.002 gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 43 0.003 gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 43 0.003 gi|58530840 desmoplakin isoform I [Homo sapiens] 42 0.007 gi|55770834 centromere protein F [Homo sapiens] 40 0.015 gi|38044112 restin isoform b [Homo sapiens] 39 0.033 gi|4506751 restin isoform a [Homo sapiens] 39 0.033 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 39 0.033 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 39 0.043 gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 39 0.056 gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 39 0.056 gi|45505178 cancer antigen 1 [Homo sapiens] 39 0.056 gi|156139122 CXXC finger 6 [Homo sapiens] 38 0.073 gi|115648142 centrosomal protein 164kDa [Homo sapiens] 38 0.073 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 38 0.095 gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 37 0.12 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 37 0.12 gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 37 0.12 gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 37 0.12 gi|45439327 periplakin [Homo sapiens] 37 0.12 gi|221219020 NYD-SP11 protein [Homo sapiens] 37 0.16 gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] 37 0.16 gi|169213511 PREDICTED: hypothetical protein [Homo sapiens] 37 0.16 >gi|222537754 hypothetical protein LOC375337 [Homo sapiens] Length = 1692 Score = 3381 bits (8767), Expect = 0.0 Identities = 1692/1692 (100%), Positives = 1692/1692 (100%) Query: 1 MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGR 60 MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGR Sbjct: 1 MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGR 60 Query: 61 GEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKR 120 GEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKR Sbjct: 61 GEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKR 120 Query: 121 KVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLEN 180 KVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLEN Sbjct: 121 KVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLEN 180 Query: 181 PPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCND 240 PPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCND Sbjct: 181 PPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCND 240 Query: 241 ENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDL 300 ENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDL Sbjct: 241 ENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDL 300 Query: 301 YQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELML 360 YQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELML Sbjct: 301 YQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELML 360 Query: 361 QENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTI 420 QENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTI Sbjct: 361 QENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTI 420 Query: 421 EPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKL 480 EPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKL Sbjct: 421 EPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKL 480 Query: 481 SCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTH 540 SCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTH Sbjct: 481 SCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTH 540 Query: 541 LTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEE 600 LTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEE Sbjct: 541 LTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEE 600 Query: 601 LSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIH 660 LSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIH Sbjct: 601 LSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIH 660 Query: 661 RKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDN 720 RKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDN Sbjct: 661 RKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDN 720 Query: 721 LSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNS 780 LSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNS Sbjct: 721 LSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNS 780 Query: 781 KPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRK 840 KPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRK Sbjct: 781 KPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRK 840 Query: 841 ITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGE 900 ITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGE Sbjct: 841 ITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGE 900 Query: 901 HQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEV 960 HQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEV Sbjct: 901 HQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEV 960 Query: 961 ANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGEC 1020 ANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGEC Sbjct: 961 ANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGEC 1020 Query: 1021 QFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKN 1080 QFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKN Sbjct: 1021 QFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKN 1080 Query: 1081 VGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELC 1140 VGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELC Sbjct: 1081 VGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELC 1140 Query: 1141 LLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLK 1200 LLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLK Sbjct: 1141 LLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLK 1200 Query: 1201 ILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAV 1260 ILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAV Sbjct: 1201 ILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAV 1260 Query: 1261 LEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFC 1320 LEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFC Sbjct: 1261 LEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFC 1320 Query: 1321 ACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSK 1380 ACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSK Sbjct: 1321 ACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSK 1380 Query: 1381 GRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWI 1440 GRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWI Sbjct: 1381 GRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWI 1440 Query: 1441 INTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSL 1500 INTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSL Sbjct: 1441 INTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSL 1500 Query: 1501 LFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSA 1560 LFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSA Sbjct: 1501 LFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSA 1560 Query: 1561 LSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKR 1620 LSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKR Sbjct: 1561 LSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKR 1620 Query: 1621 CEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENM 1680 CEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENM Sbjct: 1621 CEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENM 1680 Query: 1681 KWAGKVWLFSNH 1692 KWAGKVWLFSNH Sbjct: 1681 KWAGKVWLFSNH 1692 >gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens] Length = 1758 Score = 47.0 bits (110), Expect = 2e-04 Identities = 62/243 (25%), Positives = 99/243 (40%), Gaps = 30/243 (12%) Query: 699 RKEVNAKSSEREAYSPLELLDNLSGADVR---QNRSKENVSMMMLGPQTLSIRNSVTPVQ 755 R+EV A E + L+L + S + R +N ++V G QT + V Sbjct: 816 RQEVKAIKEEMQE---LKLNSSKSASHHRWPTENYGPDSVPDGYQGSQTF--HGAPLTVA 870 Query: 756 ASSDSFYNKKSYSISPSFTKQGNNSKPSNHVSEPGN----IVSNKEVASLTVENNAFS-- 809 + S Y YS SP++ Q +N G+ S KE S+ V + F Sbjct: 871 TTGPSVY----YSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFG 926 Query: 810 -CDPGYVEKSPSFCCNEQETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLI 864 +PG EK F+ +S + GR + + S F D+ K+ + Sbjct: 927 ISEPGNQEKESEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQF 986 Query: 865 DVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLREL 924 + DP+ G S GE F+S+ K++ + N +G+ + D Y K E SDD+ Sbjct: 987 G--KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDAY-----KTEDSDDIHFE 1039 Query: 925 PVL 927 PV+ Sbjct: 1040 PVV 1042 >gi|147903302 MAP7 domain containing 3 [Homo sapiens] Length = 876 Score = 46.6 bits (109), Expect = 2e-04 Identities = 120/588 (20%), Positives = 224/588 (38%), Gaps = 51/588 (8%) Query: 104 KEAELPLQTERHTKEK-RKVTEASSDDPQPGLDLVRK---ESLTSSESFQTVECLQSLGK 159 KE + LQ E+ +E+ RK+ E + Q + K + E F + ++L + Sbjct: 94 KERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAI-LYRTLER 152 Query: 160 ESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEF-QDELYKNTPKYSCNILSP-- 216 + + +++ + ++ N K + K+E L + P S + + Sbjct: 153 RRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVA 212 Query: 217 ----EVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFS------KKENLR 266 + E +S L RD N HS ++ + G +V + + + LR Sbjct: 213 KRKTDKERSSSLNRRDSNL--HSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELR 270 Query: 267 SLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSV 326 ++ T IP + EE+ + + P+ S + N + C + + ++ V Sbjct: 271 AVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFC---NTSMEASPKAGV 327 Query: 327 GRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSH 386 G P V+ + + + SE+ + + ++ EA K L + KVS Sbjct: 328 GMAPEVSTDSFPVVSVDVSPVVSTYD---SEMSMDASPELSI--EALPKVDLETVPKVS- 381 Query: 387 NTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDF 446 V+ + L P V E E V A + ++E K E A P + KE Sbjct: 382 -IVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVA--PKESVKGSPKESM 438 Query: 447 KSMKSFIGKSPNEYHIE---RRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARIS 503 ++ + K+ + +E S + R A ++ ++ Q IP+ KR Y C + S Sbjct: 439 EASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWS 498 Query: 504 AWCWKKASLPESSYFLRGSQESCRQVDVP--KHQTNQTHLTDSKLLLQSSLTETNTESSS 561 + LP R Q++C +P Q+ QT + +Q +L+ + S+ Sbjct: 499 SSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTV 558 Query: 562 KEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELS-------RRGSEVISNTTE 614 K+K ++ S + A+ M+ +E K I + E + RR + E Sbjct: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEE 618 Query: 615 DTQLTSETQSLTGNK-----KKARGNLTKLNLTATSKDGQEANNSAGK 657 + + E Q K K+A G + +L KDGQ+ N + K Sbjct: 619 EERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKL--KDGQQQNETKKK 664 >gi|150418007 RAN binding protein 2 [Homo sapiens] Length = 3224 Score = 45.1 bits (105), Expect = 6e-04 Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 23/165 (13%) Query: 770 SPSFTKQGNNSKPSNHVSEPGNIVSNKEVASLTVENNAFS---CDPGYVEKSPSFCCNEQ 826 SPSF QG+++ S KE S+ V + F +PG EK Sbjct: 1869 SPSFMFQGSSNT---------EFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG 1919 Query: 827 ETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGEL 882 F+ +S + GR + + S F D+ K+ + + DP+ G S GE Sbjct: 1920 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFG--KKDPNFKGFSGAGEK 1977 Query: 883 SFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVL 927 F+S+ K++ + N +G+ + D Y K E SDD+ PV+ Sbjct: 1978 LFSSQYGKMANKANTSGDFEKDDDAY-----KTEDSDDIHFEPVV 2017 >gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapiens] Length = 1756 Score = 43.1 bits (100), Expect = 0.002 Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 18/172 (10%) Query: 767 YSISPSFTKQGNNSKPSNHVSEPGN----IVSNKEVASLTVENNAFS---CDPGYVEKSP 819 YS SP++ Q +N G+ S KE S+ V + F +PG EK Sbjct: 870 YSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKS 929 Query: 820 SFCCNEQETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFG 875 F+ +S + GR + + S F D+ K+ + + DP+ G Sbjct: 930 EKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFG--KKDPNFKG 987 Query: 876 VSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVL 927 S GE F+S+ K++ + N +G+ + D K E SDD+ PV+ Sbjct: 988 FSGAGEKLFSSQCGKMANKANTSGDFEKDDD-----ACKTEDSDDIHFEPVV 1034 >gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapiens] Length = 1013 Score = 43.1 bits (100), Expect = 0.002 Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 18/172 (10%) Query: 767 YSISPSFTKQGNNSKPSNHVSEPGN----IVSNKEVASLTVENNAFS---CDPGYVEKSP 819 YS SP++ Q +N G+ S KE S+ V + F +PG EK Sbjct: 127 YSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKS 186 Query: 820 SFCCNEQETFRP--VSSEVRGRKIT--KNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFG 875 F+ +S + GR + + S F D+ K+ + + DP+ G Sbjct: 187 EKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFG--KKDPNFKG 244 Query: 876 VSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVL 927 S GE F+S+ K++ + N +G+ + D K E SDD+ PV+ Sbjct: 245 FSGAGEKLFSSQCGKMANKANTSGDFEKDDD-----ACKTEDSDDIHFEPVV 291 >gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] Length = 2039 Score = 43.1 bits (100), Expect = 0.002 Identities = 83/400 (20%), Positives = 149/400 (37%), Gaps = 58/400 (14%) Query: 100 LEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQ---- 155 LE + E ++ ++ TKEK E + + + D ++KES S + + + Sbjct: 697 LEKKSKLEKNIKDDKSTKEKHVSKERNFKEER---DKIKKESEKSFREEKIKDLKEEREN 753 Query: 156 ----------SLGKESIIEGIKRRIRNKKLKSLENPPLKITEN----EATQNIKVEFQDE 201 SLG +I E I + K++ +E I E+ E IK + ++ Sbjct: 754 IPTDKDSEFTSLGMSAIEESIGLHLVEKEI-DIEKQEKHIKESKEKPEKRSQIKEKDIEK 812 Query: 202 LYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSK 261 + + T + I L L +C +++ L C E K Sbjct: 813 MERKTFEKEKKIKHEHKSEKDKLDLSEC-----VDKIKEKDKLYSHHTEKCHKEGE---K 864 Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPE-ESDLYQSKTNGLLSCLQHEKNKYS 320 +N ++ + D + + + + K PE E L +SK L+ + + Sbjct: 865 SKNTAAIKKTDDREKSREKMDRKHD-----KEKPEKERHLAESKEKHLMEKKNKQSDNSE 919 Query: 321 IEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNV 380 +S G+ K +L +K E + N N + ++ I DG +A+ + PL++ Sbjct: 920 YSKSEKGKNKEKDRELDKK--EKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSL 977 Query: 381 LRKVSHNTVSLMDHLLSVPETVEKETSS---------EHHVNAVFQKTIEPLLKEETENA 431 K D L P+ EK+ + H + + I LLK ++E A Sbjct: 978 KEKTK-------DEPLKTPDGKEKDKKDKDIDRYKERDKHKDKI---QINSLLKLKSE-A 1026 Query: 432 SEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDL 471 +P S ASK+ K + + ER S +DL Sbjct: 1027 DKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDL 1066 >gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] Length = 2062 Score = 43.1 bits (100), Expect = 0.002 Identities = 83/400 (20%), Positives = 149/400 (37%), Gaps = 58/400 (14%) Query: 100 LEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQ---- 155 LE + E ++ ++ TKEK E + + + D ++KES S + + + Sbjct: 720 LEKKSKLEKNIKDDKSTKEKHVSKERNFKEER---DKIKKESEKSFREEKIKDLKEEREN 776 Query: 156 ----------SLGKESIIEGIKRRIRNKKLKSLENPPLKITEN----EATQNIKVEFQDE 201 SLG +I E I + K++ +E I E+ E IK + ++ Sbjct: 777 IPTDKDSEFTSLGMSAIEESIGLHLVEKEI-DIEKQEKHIKESKEKPEKRSQIKEKDIEK 835 Query: 202 LYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSK 261 + + T + I L L +C +++ L C E K Sbjct: 836 MERKTFEKEKKIKHEHKSEKDKLDLSEC-----VDKIKEKDKLYSHHTEKCHKEGE---K 887 Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPE-ESDLYQSKTNGLLSCLQHEKNKYS 320 +N ++ + D + + + + K PE E L +SK L+ + + Sbjct: 888 SKNTAAIKKTDDREKSREKMDRKHD-----KEKPEKERHLAESKEKHLMEKKNKQSDNSE 942 Query: 321 IEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNV 380 +S G+ K +L +K E + N N + ++ I DG +A+ + PL++ Sbjct: 943 YSKSEKGKNKEKDRELDKK--EKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSL 1000 Query: 381 LRKVSHNTVSLMDHLLSVPETVEKETSS---------EHHVNAVFQKTIEPLLKEETENA 431 K D L P+ EK+ + H + + I LLK ++E A Sbjct: 1001 KEKTK-------DEPLKTPDGKEKDKKDKDIDRYKERDKHKDKI---QINSLLKLKSE-A 1049 Query: 432 SEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDL 471 +P S ASK+ K + + ER S +DL Sbjct: 1050 DKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDL 1089 >gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo sapiens] Length = 1591 Score = 42.7 bits (99), Expect = 0.003 Identities = 106/560 (18%), Positives = 221/560 (39%), Gaps = 83/560 (14%) Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEE---SDLYQSKTNGL---------L 309 ++ L SL + + + +TEEN + KL E ++ Q+K N + Sbjct: 864 QKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAV 923 Query: 310 SCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTE----MNFSNEYNKSELMLQENQM 365 CLQ+EK++ +E ++ +K +++ E V E ++ N+ K +L+ E Q Sbjct: 924 ICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVEND-EKLQLLRAELQS 982 Query: 366 IADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLK 425 + E + L V R + + DH +S+ E ++KE ++ +N + + E + + Sbjct: 983 LEQSHLKELEDTLQV-RHIQEFEKVMTDHRVSLEE-LKKE--NQQIINQIQESHAEIIQE 1038 Query: 426 EETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIE---RRSSREDLRSASEELKLSC 482 +E + ++ K S + + + +E + + ++++ EE + Sbjct: 1039 KEKQ-------------LQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQ 1085 Query: 483 QRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLT 542 + T+ K+ L + + LR Q ++ Q L Sbjct: 1086 KETL----------------------KSLLEQETENLRTEISKLNQKIQDNNENYQVGLA 1123 Query: 543 DSKLLLQSSLTETNTESSSKEKLDSN--SNCLSSVSAVEPTLMVI----KEPIIKDDKKI 596 + + L+ + +E S+ + +SN L+ V+++ I KE II+ K+ Sbjct: 1124 ELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKL 1183 Query: 597 KSE--ELSRRGSEVISNTTEDTQ-----LTSETQSLTGNKKKARGNLT-KLNLTATSKDG 648 SE L R+ E I+ E + L + Q L ++++ R L KLN + Sbjct: 1184 DSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNC-----EK 1238 Query: 649 QEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSE 708 EA +A K + + ++ + + VK L K P + + + A+ E Sbjct: 1239 DEAIQTALKEFKLEREVVEKELL--EKVKHLENQIA---KSPAIDSTRGDSSSLVAELQE 1293 Query: 709 REAYSPLELLDNLSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYS 768 + + L+ L + R+N +NV ++ Q + +T + ++ N S Sbjct: 1294 KLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1353 Query: 769 ISPSFTKQGNNSKPSNHVSE 788 + + +Q + +SE Sbjct: 1354 LKSTMQQQERDKDLIESLSE 1373 >gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo sapiens] Length = 1594 Score = 42.7 bits (99), Expect = 0.003 Identities = 106/560 (18%), Positives = 221/560 (39%), Gaps = 83/560 (14%) Query: 262 KENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEE---SDLYQSKTNGL---------L 309 ++ L SL + + + +TEEN + KL E ++ Q+K N + Sbjct: 864 QKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAV 923 Query: 310 SCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTE----MNFSNEYNKSELMLQENQM 365 CLQ+EK++ +E ++ +K +++ E V E ++ N+ K +L+ E Q Sbjct: 924 ICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVEND-EKLQLLRAELQS 982 Query: 366 IADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLK 425 + E + L V R + + DH +S+ E ++KE ++ +N + + E + + Sbjct: 983 LEQSHLKELEDTLQV-RHIQEFEKVMTDHRVSLEE-LKKE--NQQIINQIQESHAEIIQE 1038 Query: 426 EETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIE---RRSSREDLRSASEELKLSC 482 +E + ++ K S + + + +E + + ++++ EE + Sbjct: 1039 KEKQ-------------LQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQ 1085 Query: 483 QRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLT 542 + T+ K+ L + + LR Q ++ Q L Sbjct: 1086 KETL----------------------KSLLEQETENLRTEISKLNQKIQDNNENYQVGLA 1123 Query: 543 DSKLLLQSSLTETNTESSSKEKLDSN--SNCLSSVSAVEPTLMVI----KEPIIKDDKKI 596 + + L+ + +E S+ + +SN L+ V+++ I KE II+ K+ Sbjct: 1124 ELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKL 1183 Query: 597 KSE--ELSRRGSEVISNTTEDTQ-----LTSETQSLTGNKKKARGNLT-KLNLTATSKDG 648 SE L R+ E I+ E + L + Q L ++++ R L KLN + Sbjct: 1184 DSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNC-----EK 1238 Query: 649 QEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSE 708 EA +A K + + ++ + + VK L K P + + + A+ E Sbjct: 1239 DEAIQTALKEFKLEREVVEKELL--EKVKHLENQIA---KSPAIDSTRGDSSSLVAELQE 1293 Query: 709 REAYSPLELLDNLSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYS 768 + + L+ L + R+N +NV ++ Q + +T + ++ N S Sbjct: 1294 KLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1353 Query: 769 ISPSFTKQGNNSKPSNHVSE 788 + + +Q + +SE Sbjct: 1354 LKSTMQQQERDKDLIESLSE 1373 >gi|58530840 desmoplakin isoform I [Homo sapiens] Length = 2871 Score = 41.6 bits (96), Expect = 0.007 Identities = 110/547 (20%), Positives = 215/547 (39%), Gaps = 90/547 (16%) Query: 156 SLGKESIIEGIKRRI----RNKKLKSLENPPLKITENEATQNIK-VEFQDELYKNT-PKY 209 ++ KE G + +I R + S E LK T + T+N++ VE + K T + Sbjct: 1381 TMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEV 1440 Query: 210 SCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLA 269 S EVE V ++R + + +D + + + K+ N R Sbjct: 1441 SQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCL 1500 Query: 270 EKSDTNSIPQLLQTEENVMG------VNKLLPEESDLYQ-------------------SK 304 E D N+ Q +Q + +NKL +E +L + ++ Sbjct: 1501 E--DENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITR 1558 Query: 305 TNGLLSCLQHEKNKYSIEESSVGRKPR----KRMKLSEKAD--------ETVTEMNFSNE 352 L LQ +K K E + + R KR KL E+ + + + N + + Sbjct: 1559 FQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQ 1618 Query: 353 YNKSELM-------LQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKE 405 ++ ++ L++ + + DG E + LR++S +L LL E+V++ Sbjct: 1619 LEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQ- 1677 Query: 406 TSSEHHVNAVFQKTIEPLLK---------EETENASEPLGYESMASKEDFKSMK---SFI 453 H N FQK IE + E ++ +E L E + +E+ ++++ + Sbjct: 1678 ---AHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDL 1734 Query: 454 GKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASL- 512 + +E ++ ++ +LRS +L++S RT+ + G I+ ++ +L Sbjct: 1735 RRGRSEADSDKNATILELRS---QLQISNNRTLELQG----------LINDLQRERENLR 1781 Query: 513 PESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSK--EKLDSNSN 570 E F + + E+ ++ K+Q Q LL++ + E + + ++L+ + Sbjct: 1782 QEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKS 1841 Query: 571 CLSSVSAVEPTLMVIKEPIIKD------DKKIKSEELSRRGSEVISNTTEDTQLTSETQS 624 L + + V+ L K+ I D K E + + SE + E L SE + Sbjct: 1842 TLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIER 1901 Query: 625 LTGNKKK 631 L K+ Sbjct: 1902 LQAEIKR 1908 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 40.4 bits (93), Expect = 0.015 Identities = 78/386 (20%), Positives = 135/386 (34%), Gaps = 70/386 (18%) Query: 260 SKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKY 319 +K++NL S E + QLLQ + +L QS NGL+ ++ K K Sbjct: 2466 AKEQNLSSQVECLELEKA-QLLQGLDEAKNNYIVL-------QSSVNGLIQEVEDGKQKL 2517 Query: 320 SIEESSVGRKPRK---RMKLSEKADETVTEMNFSNEYN------------KSELMLQENQ 364 ++ + R + + +L K + E E N K +++ +N Sbjct: 2518 EKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNA 2577 Query: 365 MIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLL 424 + D E S N+ ++ + M + V + KET + ++ + QKT E L Sbjct: 2578 SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAE--L 2635 Query: 425 KEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQR 484 +EE L E E+ KS K + ++L + ELK S Sbjct: 2636 QEELSGEKNRLAGELQLLLEEIKSSKDQL---------------KELTLENSELKKSLD- 2679 Query: 485 TIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDS 544 C K + + +E + + H+ + H Sbjct: 2680 ---------------------CMHKDQVEKEGKV----REEIAEYQLRLHEAEKKH---Q 2711 Query: 545 KLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRR 604 LLL ++ + +EKL S CLSS +E L+ + + + K ++ L Sbjct: 2712 ALLLDTNKQYEVEIQTYREKLTSKEECLSS-QKLEIDLLKSSKEELNNSLKATTQILEEL 2770 Query: 605 GSEVISNTTEDTQLTSETQSLTGNKK 630 + N QL E + G K Sbjct: 2771 KKTKMDNLKYVNQLKKENERAQGKMK 2796 Score = 38.5 bits (88), Expect = 0.056 Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 20/231 (8%) Query: 257 ENFSKKEN--LRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKT----NGLLS 310 E F EN R +EK+ L+ + V+ KL E+ + + K LS Sbjct: 1895 ERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELS 1954 Query: 311 CLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGK 370 + E+N+ E ++ +K +LSEK E E+ E ++SE + Sbjct: 1955 VVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQEL----ESHQSECL-----HCIQVA 2005 Query: 371 EAETKSPLNVLRKVSHNTVSLM---DHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEE 427 EAE K +L+ +S + L+ HL +++EK++ + + I L KE+ Sbjct: 2006 EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEK 2065 Query: 428 TENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEEL 478 E ++ S+ D++ + + K+ +E+ L S EE+ Sbjct: 2066 ELLVKESESLQARLSESDYEKLN--VSKALEAALVEKGEFALRLSSTQEEV 2114 Score = 37.4 bits (85), Expect = 0.12 Identities = 56/327 (17%), Positives = 133/327 (40%), Gaps = 24/327 (7%) Query: 138 RKESLTSSESFQTV--ECLQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIK 195 ++E SFQT+ EC+Q K + + +++ + E L + + N++ Sbjct: 397 QEELSRQQRSFQTLDQECIQM--KARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLE 454 Query: 196 VEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKG-------CNDENNLPYKP 248 EF+ +L + + + + S+ +++ N S C+ E L K Sbjct: 455 -EFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAEL--KN 511 Query: 249 DGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSK--TN 306 C++ ++NF+++ ++ ++++ + + + +EN + + KL +DL + + + Sbjct: 512 IKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQ 571 Query: 307 GLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMI 366 LL +H + + + S ++ + + E + E+ E EN+ + Sbjct: 572 DLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEEL--KEEKTLFSCWKSENEKL 629 Query: 367 ADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSE---HHVNAVFQKTIEPL 423 E+E + N+ K++H L + E E+ + E +++ + L Sbjct: 630 LTQMESEKE---NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686 Query: 424 LKEETENASEPLGYESMASKEDFKSMK 450 + E ++ L Y + K +F K Sbjct: 687 DSKSVEVETQKLAYMELQQKAEFSDQK 713 Score = 35.0 bits (79), Expect = 0.62 Identities = 60/290 (20%), Positives = 115/290 (39%), Gaps = 30/290 (10%) Query: 321 IEESSVGRKPRKRMKLSE--KADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPL 378 + +S V ++ KL E A + V S NK + E Q++ D E E ++ + Sbjct: 873 MHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK----ELQLLNDKVETE-QAEI 927 Query: 379 NVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEE--TENASEPLG 436 L+K +H + L + ET+ E + ++ ++ IE L +E + + L Sbjct: 928 QELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987 Query: 437 YESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTG------ 490 E M + +S ++I ER S +L ++ KL + TG Sbjct: 988 QEKMNLIQKSESFANYID--------EREKSISELSDQYKQEKLILLQRCEETGNAYEDL 1039 Query: 491 --KRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLL 548 K +++ + SL E+ + E ++ +HQ T L ++ Sbjct: 1040 SQKYKAAQEKNSKLECLLNECTSLCENR---KNELEQLKEAFAKEHQEFLTKLAFAEERN 1096 Query: 549 QSSLTETNT--ESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKI 596 Q+ + E T ++ E D+ +N S ++ +M +KE K K++ Sbjct: 1097 QNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEV 1146 >gi|38044112 restin isoform b [Homo sapiens] Length = 1392 Score = 39.3 bits (90), Expect = 0.033 Identities = 74/405 (18%), Positives = 153/405 (37%), Gaps = 66/405 (16%) Query: 275 NSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGL----------LSCLQHEKNKYSIEES 324 N QL TEE ++ ++ L S+ +S+ L + L+ EKN S + S Sbjct: 715 NFTSQLKATEEKLLDLDALRKASSE-GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKAS 773 Query: 325 SVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEA-----ETKSPLN 379 S+ R+ + R E ++E++ E + EL + + + +EA + +N Sbjct: 774 SITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVN 833 Query: 380 VLRKVSHNTVSLMDHLLSVPETV--------EKETSSEHHVNA--VFQKTIEPLLKEETE 429 L + L L + E + EK+ E + A + I ++K + Sbjct: 834 KLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD 893 Query: 430 NASE--PLGYESMASKEDFKSMK----------SFIGKSPNEYHIERRSSREDLRSASEE 477 N+S+ + E + D + ++ SF+ KS + ++ S+++ EE Sbjct: 894 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 953 Query: 478 LKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVP-KHQT 536 K +R + K+ + S C+++ + T Sbjct: 954 EKKELERKLSDLEKK--------------------------METSHNQCQELKARYERAT 987 Query: 537 NQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKI 596 ++T ++L T +TE K + NS L + + K +D Sbjct: 988 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQ 1047 Query: 597 KSEELSRRGSEVISNTTEDTQLTSETQS-LTGNKKKARGNLTKLN 640 E++++ +E +++ + Q ++ Q+ L K+ N+ +LN Sbjct: 1048 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1092 >gi|4506751 restin isoform a [Homo sapiens] Length = 1427 Score = 39.3 bits (90), Expect = 0.033 Identities = 74/405 (18%), Positives = 153/405 (37%), Gaps = 66/405 (16%) Query: 275 NSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGL----------LSCLQHEKNKYSIEES 324 N QL TEE ++ ++ L S+ +S+ L + L+ EKN S + S Sbjct: 750 NFTSQLKATEEKLLDLDALRKASSE-GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKAS 808 Query: 325 SVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEA-----ETKSPLN 379 S+ R+ + R E ++E++ E + EL + + + +EA + +N Sbjct: 809 SITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVN 868 Query: 380 VLRKVSHNTVSLMDHLLSVPETV--------EKETSSEHHVNA--VFQKTIEPLLKEETE 429 L + L L + E + EK+ E + A + I ++K + Sbjct: 869 KLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD 928 Query: 430 NASE--PLGYESMASKEDFKSMK----------SFIGKSPNEYHIERRSSREDLRSASEE 477 N+S+ + E + D + ++ SF+ KS + ++ S+++ EE Sbjct: 929 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 988 Query: 478 LKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVP-KHQT 536 K +R + K+ + S C+++ + T Sbjct: 989 EKKELERKLSDLEKK--------------------------METSHNQCQELKARYERAT 1022 Query: 537 NQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKI 596 ++T ++L T +TE K + NS L + + K +D Sbjct: 1023 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQ 1082 Query: 597 KSEELSRRGSEVISNTTEDTQLTSETQS-LTGNKKKARGNLTKLN 640 E++++ +E +++ + Q ++ Q+ L K+ N+ +LN Sbjct: 1083 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1127 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 39.3 bits (90), Expect = 0.033 Identities = 64/324 (19%), Positives = 120/324 (37%), Gaps = 30/324 (9%) Query: 337 SEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLL 396 S+ A+E N + NK E+M+ + + +E + RK+ T L D + Sbjct: 1013 SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA 1072 Query: 397 SVPETVEK-----ETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKSMKS 451 + +++ E A+ + E L K L + +EDF+S K+ Sbjct: 1073 ELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKA 1132 Query: 452 FIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARISAWCWKKAS 511 S N+ ++R E+L + EL+ + T RT A + K + Sbjct: 1133 ----SRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL------KKA 1182 Query: 512 LPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNC 571 L E + + RQ +H T L S+ L Q+ + N E + + N Sbjct: 1183 LEEETKNHEAQIQDMRQ----RHATALEEL--SEQLEQAKRFKANLEKNKQGLETDNKEL 1236 Query: 572 LSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKK 631 V ++ +K + + K ++L + E+ + +E +L E + Sbjct: 1237 ACEVKVLQQ---------VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN 1287 Query: 632 ARGNLTKLNLTATSKDGQEANNSA 655 N++ L A K + A ++A Sbjct: 1288 ELDNVSTLLEEAEKKGIKFAKDAA 1311 Score = 37.4 bits (85), Expect = 0.12 Identities = 92/453 (20%), Positives = 182/453 (40%), Gaps = 68/453 (15%) Query: 76 KAARRQVEGRRGPVSPSDSSDPRGLE-----AAKEAELPLQTERHTKEKRKVTEASSDDP 130 KA+R + E ++ +S + LE A + EL + E+ E +K E + + Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH 1190 Query: 131 QPGLDLVRKESLTSSESF---------------QTVECLQSLGKE-----SIIEGIKRRI 170 + + +R+ T+ E + + L++ KE +++ +K Sbjct: 1191 EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAES 1250 Query: 171 RNKKLK---SLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLR 227 +K+ K ++ K++E + ++VE ++ K L E++N S L L Sbjct: 1251 EHKRKKLDAQVQELHAKVSEGD---RLRVELAEKASK---------LQNELDNVSTL-LE 1297 Query: 228 DCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEK--SDTNSIPQLLQTEE 285 + K D +L + + E +K NL S + + NS+ + + EE Sbjct: 1298 EAEK-KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEE 1356 Query: 286 NVMG--VNKLLPEESDLYQSKTN-----GLLSCLQHEKNKYSIEESSVGRKPRKRMKLSE 338 ++L +S L +K G + L+ K K + ++ ++ ++ + Sbjct: 1357 EARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYD 1416 Query: 339 KADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVL---RKVSHNTVSLMDHL 395 K ++T + E + + L + +A E + K +L + +S D Sbjct: 1417 KLEKTKNRLQ--QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDR- 1473 Query: 396 LSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKSMKSFIGK 455 + E EKET + A+ ++ +E KEE E ++ L A ED S K +GK Sbjct: 1474 -AEAEAREKETKALSLARAL-EEALEA--KEEFERQNKQL----RADMEDLMSSKDDVGK 1525 Query: 456 SPNEYHIERRSSR---EDLRSASEELKLSCQRT 485 + +E +R+ E++R+ EEL+ Q T Sbjct: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 38.9 bits (89), Expect = 0.043 Identities = 146/704 (20%), Positives = 280/704 (39%), Gaps = 118/704 (16%) Query: 98 RGLEAAKEAELPL-QTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQS 156 R +E+ K A + + Q + KE E+ + + GL+L++ SF+ E L Sbjct: 708 RNVESLKCASMKMAQLQLENKE----LESEKEQLKKGLELLKA-------SFKKTERL-- 754 Query: 157 LGKESIIEGIKRRIRNKKL-KSLENPPLKITENEAT-QNIKVEFQDELYKNTP--KYSCN 212 E +G+ I N++L K+LEN KI + E+ Q++++E Q L KN K S Sbjct: 755 ---EVSYQGLD--IENQRLQKTLENSNKKIQQLESELQDLEMENQT-LQKNLEELKISSK 808 Query: 213 ILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKS 272 L + N L+ K EN + LR AE Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKEN--------------------KRLRQQAEIK 848 Query: 273 DTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLL--SCLQ----HEKNKYSIEESSV 326 DT EEN + + L E L SK G+ SC++ ++NK ++ +++ Sbjct: 849 DTT-------LEENNVKIGNLEKENKTL--SKEIGIYKESCVRLKELEKENKELVKRATI 899 Query: 327 GRKPRKRMKLSEKADETVTEMNFSNEYNK-----------SELMLQENQMIADGK----E 371 K ++ + E + +N+ K E +L + Q D + E Sbjct: 900 DIKTLVTLR-EDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE 958 Query: 372 AETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETEN- 430 ++ +S L ++ ++ ++ L ++ E +K E L + + E Sbjct: 959 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT---VKKNYEALKQRQDEER 1015 Query: 431 ---ASEPL-GYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTI 486 +S P+ G ++ +E ++ + + +ER ++ L++ + LK ++ Sbjct: 1016 MVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT--LQAEKQALKTQLKQLE 1073 Query: 487 PMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTD--S 544 A+I A + SL E + L+ +Q + QV+ + T L + + Sbjct: 1074 TQNNNLQ------AQILALQRQTVSLQEQNTTLQ-TQNAKLQVENSTLNSQSTSLMNQNA 1126 Query: 545 KLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIK------EPIIKDDKKIKS 598 +LL+Q S E ES KE+ D S S + E ++ + E +I +KS Sbjct: 1127 QLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKS 1186 Query: 599 EELSRRGSEVISNTTED--TQLTSETQSLTGNKKKARGNLTKL-----NLTATSKDGQEA 651 + + EV ED QL + L +K + K+ N + + ++ Sbjct: 1187 ---AHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKL 1243 Query: 652 NNSAGKTIHRKACIAQQTFIV----PDLVKILNTGRLTNFKIPLLKNK-SEKRKEVNAKS 706 + H + + ++T ++ +L +LN +L ++ +K E+ ++++ S Sbjct: 1244 CGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITS 1303 Query: 707 SEREAYSPLELLDNLSGADVRQNRS-KENVSMMMLGPQTLSIRN 749 ++ + ELL L G +NR + + +ML +TL +N Sbjct: 1304 TKLN--NQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1345 >gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b [Homo sapiens] Length = 1814 Score = 38.5 bits (88), Expect = 0.056 Identities = 47/189 (24%), Positives = 75/189 (39%), Gaps = 6/189 (3%) Query: 294 LPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRM---KLSEKADET-VTEMNF 349 L EE L L+ CL+ EK++ + + +V + + EK ET +M Sbjct: 222 LIEELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEH 281 Query: 350 SNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSE 409 E N E +Q + KE E + K L L S + VE+ S Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341 Query: 410 HHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKS--MKSFIGKSPNEYHIERRSS 467 ++A F K E L K +T+ YE+ S ++ S ++S E H RRS Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSI 401 Query: 468 REDLRSASE 476 ++ + S+ Sbjct: 402 KKITQELSD 410 >gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a [Homo sapiens] Length = 1893 Score = 38.5 bits (88), Expect = 0.056 Identities = 47/189 (24%), Positives = 75/189 (39%), Gaps = 6/189 (3%) Query: 294 LPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRM---KLSEKADET-VTEMNF 349 L EE L L+ CL+ EK++ + + +V + + EK ET +M Sbjct: 222 LIEELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEH 281 Query: 350 SNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSE 409 E N E +Q + KE E + K L L S + VE+ S Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341 Query: 410 HHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKS--MKSFIGKSPNEYHIERRSS 467 ++A F K E L K +T+ YE+ S ++ S ++S E H RRS Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSI 401 Query: 468 REDLRSASE 476 ++ + S+ Sbjct: 402 KKITQELSD 410 >gi|45505178 cancer antigen 1 [Homo sapiens] Length = 641 Score = 38.5 bits (88), Expect = 0.056 Identities = 29/96 (30%), Positives = 53/96 (55%), Gaps = 5/96 (5%) Query: 111 QTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTV-ECLQSLGKESIIEGIKRR 169 + ER + K+++ +A++ LDL+++E + F ++ E Q L KE++ E K + Sbjct: 315 EVERLQQLKKELEKATAS----ALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLK 370 Query: 170 IRNKKLKSLENPPLKITENEATQNIKVEFQDELYKN 205 R +KL + ++ENE T+NIK++ Q KN Sbjct: 371 SRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKN 406 >gi|156139122 CXXC finger 6 [Homo sapiens] Length = 2136 Score = 38.1 bits (87), Expect = 0.073 Identities = 102/530 (19%), Positives = 200/530 (37%), Gaps = 73/530 (13%) Query: 237 GCNDENNLPYKPDGGCMHVAENFSKKENLRS--LAEKSDTNSIPQLLQTEE-----NVMG 289 G +E L P H EN +K E+ + EK N QL + NV Sbjct: 678 GHGEEQKLELNP-----HTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPE 732 Query: 290 VNKLLPEESDLYQSKT---------NGL--LSCLQHEKN----KYSIEESSVGRKPRKRM 334 K E D ++K+ NG+ + CL E N K++IEE + Sbjct: 733 AEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYK 792 Query: 335 KLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDH 394 L + A+ + + + + L + N ++ S + H++ S+++H Sbjct: 793 FLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSS-------IPHSSHSIINH 845 Query: 395 LLSV------PETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKS 448 S+ P+T E S E + Q ++ L+K+ + + E++ + S Sbjct: 846 HASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPS 905 Query: 449 MKSFIGKSPNEYHIERRSS-------------REDLRSASEELKLSCQRTIPMTGKRTWP 495 S KS + E+R++ R+DL+ + + + P K++ Sbjct: 906 ENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQS-- 963 Query: 496 YYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTET 555 SC + + + +L S + Q H+ ++ + S + +S+ ++ Sbjct: 964 --SCNTV-VFNGQTTTLSNSHI-----NSATNQASTKSHEYSKVTNSLSLFIPKSNSSKI 1015 Query: 556 NTESSSKEKLDSNSNCLSSVSAVEPTLMVIK--EPIIKDDKKIKSEELSRRGSEVISNTT 613 +T S + + + NC + + + P ++ ++ KK+ S++LS + + + Sbjct: 1016 DTNKSIAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDA-THTQIE 1074 Query: 614 ED--TQLTSETQSLTGNKKKARGNLTKLNLTATSK---DGQEANNSAGKTIHRKACIAQQ 668 ED TQLT + N K K+ T TS + Q+ N TI +K + Sbjct: 1075 EDVATQLTQLASIIKINYIKPEDK--KVESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVH 1132 Query: 669 TFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELL 718 L K N + P + +K V+ + ++R+ + L + Sbjct: 1133 NNHGSSLTKQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYM 1182 >gi|115648142 centrosomal protein 164kDa [Homo sapiens] Length = 1460 Score = 38.1 bits (87), Expect = 0.073 Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 29/172 (16%) Query: 21 NLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGRGEVESDKSVAASGAGKAARR 80 +LQ+ QAP P AA C + K++ PG+ E E + A Sbjct: 523 SLQREQAPSPPAA---------CEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSP 573 Query: 81 QVEGRRGPVSPSDSSDPRGLEAAKE--AELPLQTERHTKEKRKVTEASSDDPQPGLDLVR 138 +V PV+P + L+A +E A++ Q +RH E + Q + +R Sbjct: 574 EVRSTE-PVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESK----------QEKMQQLR 622 Query: 139 KESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEA 190 E L E + + Q KE + ++ R++ K++E ++ E E+ Sbjct: 623 -EKLCQEEEEEILRLHQQ--KEQSLSSLRERLQ----KAIEEEEARMREEES 667 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 37.7 bits (86), Expect = 0.095 Identities = 144/700 (20%), Positives = 284/700 (40%), Gaps = 111/700 (15%) Query: 98 RGLEAAKEAELPL-QTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQS 156 R +E+ K A + + Q + KE E+ + + GL+L++ SF+ E L Sbjct: 708 RNVESLKCASMKMAQLQLENKE----LESEKEQLKKGLELLKA-------SFKKTERL-- 754 Query: 157 LGKESIIEGIKRRIRNKKL-KSLENPPLKITENEAT-QNIKVEFQDELYKNTP--KYSCN 212 E +G+ I N++L K+LEN KI + E+ Q++++E Q L KN K S Sbjct: 755 ---EVSYQGLD--IENQRLQKTLENSNKKIQQLESELQDLEMENQT-LQKNLEELKISSK 808 Query: 213 ILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKS 272 L + N L+ K EN + LR AE Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKEN--------------------KRLRQQAEIK 848 Query: 273 DTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLL--SCLQ----HEKNKYSIEESSV 326 DT EEN + + L E L SK G+ SC++ ++NK ++ +++ Sbjct: 849 DTT-------LEENNVKIGNLEKENKTL--SKEIGIYKESCVRLKELEKENKELVKRATI 899 Query: 327 GRKPRKRMKLSEKADETVTEMNFSNEYNK-----SELMLQENQMIADGKEAETKSPL--N 379 K ++ + E + +N+ K ++ L + +++ D + + + L + Sbjct: 900 DIKTLVTLR-EDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLES 958 Query: 380 VLRKVSHNTVSLMDHLLSVPET-VEKETSSEHHVNA---VFQKTIEPLLKEETEN----A 431 L ++ + + ++ E +E+ T+ + +K E L + + E + Sbjct: 959 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQS 1018 Query: 432 SEPL-GYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTG 490 S P+ G ++ +E ++ + + +ER ++ L++ + LK ++ Sbjct: 1019 SPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT--LQAEKQALKTQLKQLETQNN 1076 Query: 491 KRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTD--SKLLL 548 A+I A + SL E + L+ +Q + QV+ + T L + ++LL+ Sbjct: 1077 NLQ------AQILALQRQTVSLQEQNTTLQ-TQNAKLQVENSTLNSQSTSLMNQNAQLLI 1129 Query: 549 QSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIK------EPIIKDDKKIKSEELS 602 Q S E ES KE+ D S S + E ++ + E +I +KS + Sbjct: 1130 QQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKS---A 1186 Query: 603 RRGSEVISNTTED--TQLTSETQSLTGNKKKARGNLTKL-----NLTATSKDGQEANNSA 655 + EV ED QL + L +K + K+ N + + ++ Sbjct: 1187 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 1246 Query: 656 GKTIHRKACIAQQTFIV----PDLVKILNTGRLTNFKIPLLKNK-SEKRKEVNAKSSERE 710 + H + + ++T ++ +L +LN +L ++ +K E+ ++++ S++ Sbjct: 1247 DRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306 Query: 711 AYSPLELLDNLSGADVRQNRS-KENVSMMMLGPQTLSIRN 749 + ELL L G +NR + + +ML +TL +N Sbjct: 1307 --NQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1344 >gi|38788333 remodeling and spacing factor 1 [Homo sapiens] Length = 1441 Score = 37.4 bits (85), Expect = 0.12 Identities = 58/221 (26%), Positives = 84/221 (38%), Gaps = 52/221 (23%) Query: 853 ILKAYEDDVLLIDVIQDD------PDLFGVSNEGELSFTSEVPKI----------SQEPN 896 +LKA D VLL + Q D P L + E E PK S+E Sbjct: 204 LLKAQIDPVLLKNSSQQDNSSRESPSL----EDEETKKEEETPKQEEQKESEKMKSEEQP 259 Query: 897 VAGEHQSTDSKYMETPVKKEPSD--DLRELPVL------------------DCGWIKPDI 936 + E++ST + ET VKKE D +L +LPV+ + K ++ Sbjct: 260 MDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFKENV 319 Query: 937 CASNSAESEIKRDPKDVNTSLGE-VANETSENETLGDFSEQIKGSDLDEKHRFTDKVITK 995 E + DPKD +S+ + VA E E G ++ H T+K + Sbjct: 320 KPIKVEVKECRADPKDTKSSMEKPVAQEPERIEF---------GGNIKSSHEITEK--ST 368 Query: 996 EEKENIYEVCKSKDSRNADFMVGECQFAVPVPKPLCLLVPP 1036 EE E + ++K + F PV PLC V P Sbjct: 369 EETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGPLCKSVTP 409 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 37.4 bits (85), Expect = 0.12 Identities = 79/431 (18%), Positives = 164/431 (38%), Gaps = 55/431 (12%) Query: 98 RGLEAAKEAELPLQTERHTK-EKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQS 156 R E +K+ E+ + T+ + +K +EA Q L +E + F+T+ Sbjct: 766 RATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQK-LTKQEEEKQILKQDFETLSQETK 824 Query: 157 LGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSP 216 + E + I+ + + +E L +TE ++ + D L + ++ Sbjct: 825 IQHEELNNRIQTTVTELQKVKMEKEAL-MTELSTVKDKLSKVSDSLKNSKSEF------- 876 Query: 217 EVENN----SVLKL-RDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEK 271 E EN ++L L + C H EN L + + + +KE S K Sbjct: 877 EKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKE------LKKSLEKEKEASHQLK 930 Query: 272 SDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPR 331 + NS+ + L +N + N+ +E Q N L + +K + + + Sbjct: 931 LELNSMQEQLIQAQNTLKQNE---KEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVL 987 Query: 332 KRMKLSEKADETVTEMN------------FSNEYNKSELMLQENQMIADGKEAETKSPLN 379 ++ +L K + +T+ N Y KS+ ++ Q G+E+E + Sbjct: 988 QKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQ 1047 Query: 380 VLRKVSH-----------------NTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEP 422 L+ V N L+ L + T+E++++ + K ++ Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQD 1107 Query: 423 LLKEETENASEPLGYES-MASKEDFK-SMKSFIGKSPNEYHIERRSSREDLRSASEELKL 480 + KE++ E + +S +A E+ K + I K E + S +++ + + +L Sbjct: 1108 IQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQL 1167 Query: 481 SCQRTIPMTGK 491 Q+ + + GK Sbjct: 1168 LIQQKLELQGK 1178 Score = 33.5 bits (75), Expect = 1.8 Identities = 104/502 (20%), Positives = 192/502 (38%), Gaps = 90/502 (17%) Query: 257 ENFSKKENLRSLAEKSD---TNSIPQLLQTE---ENVMGVNKLLPEESDLYQSKTNGLLS 310 + K + L+ K D T+S +L E E N + + DL++ K L + Sbjct: 111 KELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLAT 170 Query: 311 CLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGK 370 + K+KY E S L E A++ VT + + E NK ++Q+ + + Sbjct: 171 EIADIKSKYDEERS-----------LREAAEQKVTRL--TEELNKEATVIQD--LKTELL 215 Query: 371 EAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETEN 430 + + VL+K +LMD++ T+E+E SE LK+E + Sbjct: 216 QRPGIEDVAVLKKELVQVQTLMDNM-----TLERERESEK-------------LKDECKK 257 Query: 431 ASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTG 490 L + +S+ ++S + K P E + + ++ L+S+ EL Q Sbjct: 258 ----LQSQYASSEATISQLRSELAKGPQEVAVYVQELQK-LKSSVNELTQKNQTLTENLL 312 Query: 491 KRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQS 550 K+ Y + E S + Q + Q D+ Q Q+ L+ S ++ Sbjct: 313 KKEQDYTKL---------EEKHNEESVSKKNIQATLHQKDLDCQQL-QSRLSAS----ET 358 Query: 551 SLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRRGSEVIS 610 SL + E S EK ++ +S VE +K + + EE + G ++ S Sbjct: 359 SLHRIHVELS--EKGEATQKLKEELSEVETKYQHLKAEF--KQLQQQREEKEQHGLQLQS 414 Query: 611 NTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIHRKACIAQQTF 670 + ET+ G +A G L ++ S+ K + ++ +A Sbjct: 415 EINQLHSKLLETERQLG---EAHGRLK-----------EQRQLSSEKLMDKEQQVADLQL 460 Query: 671 IVPDLVKIL--NTGRLTNFKIPLLKNKSEKRKEVNAKSSE----REAYSPLELL------ 718 + L + L T + L K K + +++ + S REA + LE + Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGD 520 Query: 719 --DNLSGADVRQNRSKENVSMM 738 + + +SKEN+S++ Sbjct: 521 KDQKIQNLEALLQKSKENISLL 542 >gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] Length = 971 Score = 37.4 bits (85), Expect = 0.12 Identities = 46/227 (20%), Positives = 90/227 (39%), Gaps = 25/227 (11%) Query: 265 LRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEES 324 LRS + D Q+L+ E+ V N+ + + Y+ + L S L+ E + + S Sbjct: 304 LRSKTQSLDEEQKQQILELEKKV---NEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHS 360 Query: 325 SVGRKPRKRMKLSEKA-------DETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSP 377 + + ++ +A D+ +M+ ++NK +L L+E++ + + E ++ Sbjct: 361 KTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDK---NQLQQELENL 417 Query: 378 LNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGY 437 VL + + HL + E+ S + A Q ++ E L Sbjct: 418 KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQ------------DSQERLQN 465 Query: 438 ESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQR 484 E +K+ K K + E ER+ E + + EE KL + Sbjct: 466 ELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDK 512 >gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] Length = 1140 Score = 37.4 bits (85), Expect = 0.12 Identities = 46/227 (20%), Positives = 90/227 (39%), Gaps = 25/227 (11%) Query: 265 LRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEES 324 LRS + D Q+L+ E+ V N+ + + Y+ + L S L+ E + + S Sbjct: 424 LRSKTQSLDEEQKQQILELEKKV---NEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHS 480 Query: 325 SVGRKPRKRMKLSEKA-------DETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSP 377 + + ++ +A D+ +M+ ++NK +L L+E++ + + E ++ Sbjct: 481 KTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDK---NQLQQELENL 537 Query: 378 LNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGY 437 VL + + HL + E+ S + A Q ++ E L Sbjct: 538 KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQ------------DSQERLQN 585 Query: 438 ESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQR 484 E +K+ K K + E ER+ E + + EE KL + Sbjct: 586 ELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDK 632 >gi|45439327 periplakin [Homo sapiens] Length = 1756 Score = 37.4 bits (85), Expect = 0.12 Identities = 72/364 (19%), Positives = 135/364 (37%), Gaps = 43/364 (11%) Query: 263 ENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIE 322 E R+ E+ +L + +E V+ + EE +++ + + E + Sbjct: 1326 ERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKL 1385 Query: 323 ESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLR 382 + + R R+R +L + +E E E + LQ+ + +EAE + + + Sbjct: 1386 RAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445 Query: 383 KV--SHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESM 440 KV + +H L + + E H + + +E L ++ E Sbjct: 1446 KVVLQQDPQQAREHAL-----LRLQLEEEQHRRQLLEGELETLRRKLA-------ALEKA 1493 Query: 441 ASKEDFKSMKSF-IGKSPNEYHIER-RSSREDLRSASEELKLSCQRTIPMTGKRTWPYYS 498 KE +S + K E I+R +SS E+ + EL + R Sbjct: 1494 EVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLE------------ 1541 Query: 499 CARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTE 558 AR+S + + + FLR K Q + +L LQS + TE Sbjct: 1542 -ARLSELEFHNSKSSKELDFLREENH--------KLQLERQNLQLETRRLQSEINMAATE 1592 Query: 559 SSSKEKL---DSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRR-GSEVISNTTE 614 + + DS +N S + ++E L +K + DK ++ +EL +R GS + Sbjct: 1593 TRDLRNMTVADSGTNHDSRLWSLERELDDLKR--LSKDKDLEIDELQKRLGSVAVKREQR 1650 Query: 615 DTQL 618 + L Sbjct: 1651 ENHL 1654 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 37.0 bits (84), Expect = 0.16 Identities = 85/420 (20%), Positives = 157/420 (37%), Gaps = 56/420 (13%) Query: 99 GLEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLG 158 G E + E P T +RK+T+ + + L L K L E + G Sbjct: 1980 GKETLSKGETP-----ETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKG 2034 Query: 159 KESIIEGIKRRIRN-KKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPE 217 K G + ++ +KL +K E+ + + K+ +++ K K + + Sbjct: 2035 KLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKL---NKILKALQKLTRDERKLT 2091 Query: 218 VENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSI 277 E + K++ + +++ L K + +K E + ++ N + Sbjct: 2092 QEEIKMTKMKRALFVKERRLSIEQSKLDIK-EWDFSEKRSELTKDEKKLARKQRKLANKM 2150 Query: 278 PQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSV----------- 326 +++ EE K+ EES L + + +L ++ + IEE V Sbjct: 2151 RRMINKEE------KMTEEESKLARKHSEVILD----DEEEGGIEEEEVIPFLKRRWRKR 2200 Query: 327 -----GRKPRKRMKLSEKADETVTEMNFSNEYNK--SELMLQENQMIADGKEAETKSPLN 379 G KP++ K S + DE +E +FS E EL QE+ + +E E + Sbjct: 2201 KEAKRGDKPKE--KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258 Query: 380 VLRKVSHNTVSLMDHLLSVPETVEKETSSE------------HHVNAVFQKTIEPLLKEE 427 +V + + VEKE + VF++ E + +EE Sbjct: 2259 E-EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE 2317 Query: 428 TENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIP 487 TE+ S+ E S E+ + I K ++ ++ + R+ LR E LS R +P Sbjct: 2318 TESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ-RRKSLR--GRERVLSILRGVP 2374 Score = 31.6 bits (70), Expect = 6.8 Identities = 20/83 (24%), Positives = 41/83 (49%), Gaps = 2/83 (2%) Query: 586 KEPIIKDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATS 645 +E ++++DKK+K EE + ++S+ +++ Q E + + G + +T Sbjct: 1506 EEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQ 1565 Query: 646 KDGQEANNSAGKTIHRKACIAQQ 668 + QE + A IHRK A++ Sbjct: 1566 RHIQEEHKWA--RIHRKRARAEK 1586 >gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] Length = 737 Score = 37.0 bits (84), Expect = 0.16 Identities = 52/263 (19%), Positives = 95/263 (36%), Gaps = 40/263 (15%) Query: 531 VPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPII 590 + + + + T S S +T + T S+S S S+ +S + ++ + I Sbjct: 110 ITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSI 169 Query: 591 KDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQE 650 I S S + SN+T T ++ T + T T T+T+ Sbjct: 170 SSS--ITSTSTSTTSTS--SNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTT 225 Query: 651 ANNSAGK------TIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNA 704 + +++ T H+K C A + + L +++TG K R V Sbjct: 226 STSTSATSSIRKLTPHQKQCGALASAFLFGLSLLVSTG-----------TKGLGRSLVTP 274 Query: 705 KSSEREAYSPLELLDNLSGA----DVRQNRSKENVSMMMLG---------------PQTL 745 + S +P + A + RQ R + V+ G PQ L Sbjct: 275 RPSPPPPLTPQAESGGVDAAPRAPETRQVRKVDGVNPAAAGPRGGATACSGVQSRRPQGL 334 Query: 746 SIRNSVTPVQASSDSFYNKKSYS 768 ++R ++ P + S+D +N S S Sbjct: 335 ALRATLLPAKRSADMRWNSGSCS 357 >gi|169213511 PREDICTED: hypothetical protein [Homo sapiens] Length = 737 Score = 37.0 bits (84), Expect = 0.16 Identities = 52/263 (19%), Positives = 95/263 (36%), Gaps = 40/263 (15%) Query: 531 VPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPII 590 + + + + T S S +T + T S+S S S+ +S + ++ + I Sbjct: 110 ITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSI 169 Query: 591 KDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQE 650 I S S + SN+T T ++ T + T T T+T+ Sbjct: 170 SSS--ITSTSTSTTSTS--SNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTT 225 Query: 651 ANNSAGK------TIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNA 704 + +++ T H+K C A + + L +++TG K R V Sbjct: 226 STSTSATSSIRKLTPHQKQCGALASAFLFGLSLLVSTG-----------TKGLGRSLVTP 274 Query: 705 KSSEREAYSPLELLDNLSGA----DVRQNRSKENVSMMMLG---------------PQTL 745 + S +P + A + RQ R + V+ G PQ L Sbjct: 275 RPSPPPPLTPQAESGGVDAAPRAPETRQVRKVDGVNPAAAGPRGGATACSGVQSRRPQGL 334 Query: 746 SIRNSVTPVQASSDSFYNKKSYS 768 ++R ++ P + S+D +N S S Sbjct: 335 ALRATLLPAKRSADMRWNSGSCS 357 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 64,432,351 Number of Sequences: 37866 Number of extensions: 2990163 Number of successful extensions: 9323 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 19 Number of HSP's successfully gapped in prelim test: 197 Number of HSP's that attempted gapping in prelim test: 8919 Number of HSP's gapped (non-prelim): 618 length of query: 1692 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1576 effective length of database: 13,855,062 effective search space: 21835577712 effective search space used: 21835577712 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.