Search of human proteins with 222446640

Search of human proteins with 222446640

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
sapiens]
         (470 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ...   924   0.0  
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ...   904   0.0  
gi|41352721 solute carrier family 36 member 1 [Homo sapiens]          570   e-163
gi|222418631 solute carrier family 36, member 2 [Homo sapiens]        533   e-151
gi|40807351 solute carrier family 36 (proton/amino acid symporte...   425   e-119
gi|17999520 solute carrier family 32, member 1 [Homo sapiens]          67   3e-11
gi|122937281 solute carrier family 38, member 8 [Homo sapiens]         65   2e-10
gi|24429574 solute carrier family 38, member 6 [Homo sapiens]          61   2e-09
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ...    54   2e-07
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ...    54   2e-07
gi|117168277 amino acid transporter system A1 [Homo sapiens]           54   4e-07
gi|117168275 amino acid transporter system A1 [Homo sapiens]           54   4e-07
gi|193788624 solute carrier family 38, member 5 [Homo sapiens]         52   9e-07
gi|8922692 solute carrier family 38, member 7 [Homo sapiens]           48   2e-05
gi|5870893 solute carrier family 38, member 3 [Homo sapiens]           46   6e-05
gi|21361602 solute carrier family 38, member 2 [Homo sapiens]          45   1e-04
gi|219689132 solute carrier family 38, member 4 [Homo sapiens]         44   2e-04
gi|18482385 solute carrier family 38, member 4 [Homo sapiens]          44   2e-04
gi|222418629 solute carrier family 38, member 9 [Homo sapiens]         37   0.039
gi|53828674 olfactory receptor, family 13, subfamily C, member 4...    33   0.43 
gi|53828744 olfactory receptor, family 11, subfamily G, member 2...    32   0.95 
gi|116812579 transmembrane BAX inhibitor motif containing 4 [Hom...    31   2.8  
gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo sapi...    30   6.2  
gi|4757956 cadherin 16 precursor [Homo sapiens]                        30   6.2  

>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
           sapiens]
          Length = 470

 Score =  924 bits (2389), Expect = 0.0
 Identities = 470/470 (100%), Positives = 470/470 (100%)

Query: 1   MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGL 60
           MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGL
Sbjct: 1   MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGL 60

Query: 61  LGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLE 120
           LGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLE
Sbjct: 61  LGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLE 120

Query: 121 TCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREI 180
           TCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREI
Sbjct: 121 TCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREI 180

Query: 181 LTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPY 240
           LTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPY
Sbjct: 181 LTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPY 240

Query: 241 PSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYIL 300
           PSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYIL
Sbjct: 241 PSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYIL 300

Query: 301 LGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQ 360
           LGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQ
Sbjct: 301 LGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQ 360

Query: 361 VSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFY 420
           VSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFY
Sbjct: 361 VSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFY 420

Query: 421 SEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSMANSTGVHA 470
           SEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSMANSTGVHA
Sbjct: 421 SEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSMANSTGVHA 470


>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
           sapiens]
          Length = 511

 Score =  904 bits (2337), Expect = 0.0
 Identities = 470/511 (91%), Positives = 470/511 (91%), Gaps = 41/511 (8%)

Query: 1   MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGL 60
           MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGL
Sbjct: 1   MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGL 60

Query: 61  LGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLE 120
           LGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLE
Sbjct: 61  LGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLE 120

Query: 121 TCPNTWLRAHAVWGR-----------------------------------------YTVS 139
           TCPNTWLRAHAVWGR                                         YTVS
Sbjct: 121 TCPNTWLRAHAVWGRWNLALSPRLECSGKISAHCNPHLQGSSNSPAQASRVAGIYRYTVS 180

Query: 140 FLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPF 199
           FLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPF
Sbjct: 181 FLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPF 240

Query: 200 LILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGT 259
           LILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGT
Sbjct: 241 LILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGT 300

Query: 260 AIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITL 319
           AIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITL
Sbjct: 301 AIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITL 360

Query: 320 NLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVC 379
           NLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVC
Sbjct: 361 NLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVC 420

Query: 380 LTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVG 439
           LTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVG
Sbjct: 421 LTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVG 480

Query: 440 LLGCIFGTYQALYELPQPISHSMANSTGVHA 470
           LLGCIFGTYQALYELPQPISHSMANSTGVHA
Sbjct: 481 LLGCIFGTYQALYELPQPISHSMANSTGVHA 511


>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
          Length = 476

 Score =  570 bits (1470), Expect = e-163
 Identities = 288/458 (62%), Positives = 363/458 (79%), Gaps = 4/458 (0%)

Query: 3   LLGRDYNSELNSLDNGPQ-SPSESSSSITSENVHPA-GEAG-LSMMQTLIHLLKCNIGTG 59
           L   DY+ + +S D  P+ SPSE  ++++S   +   G++   +  QTLIHLLK NIGTG
Sbjct: 6   LRNEDYH-DYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTG 64

Query: 60  LLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGL 119
           LLGLPLA+KNAG+++GP+SLL IG++ VHCM IL+ CA H  +RL K+FV+YG+  MYGL
Sbjct: 65  LLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGL 124

Query: 120 ETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPRE 179
           E+ P +WLR HA WGR  V F L++TQLGFC VYF+F+ADN +Q++E A+ T+N C   E
Sbjct: 125 ESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNE 184

Query: 180 ILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIP 239
            + LTP +D R YML  LPFL+LLVFI+NL+ LS+FS LANIT L S+ +I+++I++ IP
Sbjct: 185 TVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIP 244

Query: 240 YPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYI 299
            PS+LPL+A WKT+ LFFGTAIF+FEG+GMVLPL+N+MK P++F  +LYLGM IV ILYI
Sbjct: 245 DPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYI 304

Query: 300 LLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAIS 359
            LG LGY++FG++ Q SITLNLPNCWLYQSVKL+YSIGIFFTYALQF+VPAEIIIPF +S
Sbjct: 305 SLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVS 364

Query: 360 QVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIF 419
           +  E   L VDL VR+ LVCLTC+ AILIPRLDLVISLVGSVSSSALALIIP LLE+  F
Sbjct: 365 RAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTF 424

Query: 420 YSEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQP 457
           YSE MS +TI KD +ISI+G +G + GTY+ALYEL QP
Sbjct: 425 YSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQP 462


>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
          Length = 483

 Score =  533 bits (1374), Expect = e-151
 Identities = 269/448 (60%), Positives = 344/448 (76%), Gaps = 9/448 (2%)

Query: 20  QSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSL 79
           +SPSES+    ++        G+++ Q LIHL+K N+GTG+LGLPLA+KNAG+L+GP+SL
Sbjct: 40  ESPSESAGLKKTK--------GITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSL 91

Query: 80  LAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVS 139
           L +G +  HCM IL+ CAQ   +RL K F++YG+  M+GLE  PN WL+ HA WGR+ VS
Sbjct: 92  LVMGFIACHCMHILVKCAQRFCKRLNKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVS 151

Query: 140 FLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPF 199
           F L+ITQLGFC VY +F+ADNL+Q+VE  + T+N C   E + LTP +D R YML  LPF
Sbjct: 152 FFLIITQLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNETVILTPTMDSRLYMLSFLPF 211

Query: 200 LILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGT 259
           L+LLV I+NL++L++FS LANI+ L S+ +I +YI + IP PS LPL+A+WKT+ LFFGT
Sbjct: 212 LVLLVLIRNLRILTIFSMLANISMLVSLVIIIQYITQEIPDPSRLPLVASWKTYPLFFGT 271

Query: 260 AIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITL 319
           AIF+FE +G+VLPL+N+MK+ + F  +L LGMSIV  LYI +  LGY++FG D +ASI+L
Sbjct: 272 AIFSFESIGVVLPLENKMKNARHFPAILSLGMSIVTSLYIGMAALGYLRFGDDIKASISL 331

Query: 320 NLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVC 379
           NLPNCWLYQSVKL+Y  GI  TYALQF+VPAEIIIPFAIS+VS  WAL +DLS+R  +VC
Sbjct: 332 NLPNCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTRWALPLDLSIRLVMVC 391

Query: 380 LTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVG 439
           LTC+ AILIPRLDLVISLVGSVS +ALALIIP LLE+  FYSE MS +TI KD +ISI+G
Sbjct: 392 LTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYSEGMSPLTIFKDALISILG 451

Query: 440 LLGCIFGTYQALYE-LPQPISHSMANST 466
            +G + GTYQAL E L    SH  +NST
Sbjct: 452 FVGFVVGTYQALDELLKSEDSHPFSNST 479


>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
           member 4 [Homo sapiens]
          Length = 504

 Score =  425 bits (1092), Expect = e-119
 Identities = 216/438 (49%), Positives = 300/438 (68%), Gaps = 18/438 (4%)

Query: 39  EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQ 98
           + G+S +QTL+HLLK NIGTGLLGLPLAIKNAG+++GP+SL+ IG+++VHCM IL+ C+ 
Sbjct: 56  QEGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSH 115

Query: 99  HLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMA 158
            L  R +K+ + Y +   + +E  P + L+  A WGR  V F LVITQLGFCSVY +F+A
Sbjct: 116 FLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLA 175

Query: 159 DNLQQM----------VEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQN 208
           +N++Q+          +  +  +SN C+ R +       D+R YML  LPF+ILLVFI+ 
Sbjct: 176 ENVKQVHEGFLESKVFISNSTNSSNPCERRSV-------DLRIYMLCFLPFIILLVFIRE 228

Query: 209 LKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVG 268
           LK L V S LAN++   S+ +I++Y++  +P P NLP++A WK + LFFGTA+F FEG+G
Sbjct: 229 LKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIG 288

Query: 269 MVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLP-NCWLY 327
           +VLPL+NQMK  ++F   L +GM IV  LY+ L TLGYM F  + + SITLNLP + WLY
Sbjct: 289 VVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLY 348

Query: 328 QSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVCLTCVSAIL 387
           QSVK++YS GIF TY++QF+VPAEIIIP   S+    W    +  +RS LV +TC  AIL
Sbjct: 349 QSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAIL 408

Query: 388 IPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVGLLGCIFGT 447
           IPRLD+VIS VG+VSSS LALI+P L+EI+ F  E  +   + K+I I+  G++G + GT
Sbjct: 409 IPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGT 468

Query: 448 YQALYELPQPISHSMANS 465
           Y  + E+  P    +A +
Sbjct: 469 YITVEEIIYPTPKVVAGT 486


>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
          Length = 525

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 58/276 (21%), Positives = 117/276 (42%), Gaps = 22/276 (7%)

Query: 192 YMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPS--NLPLMAN 249
           + +I    L+   F++NLK +S FS L  +       L+  Y +      +   +    +
Sbjct: 243 WSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYID 302

Query: 250 WKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKF 309
            K F +  G  +F++     +  L+  M+ P +F  ++        +L  L   + Y+ +
Sbjct: 303 VKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTW 362

Query: 310 GSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVS------- 362
             +T+  IT NLP   +   V +        +Y L F    E++      + S       
Sbjct: 363 ADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPAC 421

Query: 363 -------ESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLE 415
                  +SW L    ++R ALV  T + AI +P   L++ L GS++ + L  ++P+L  
Sbjct: 422 YSGDGRLKSWGL----TLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFH 477

Query: 416 IVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQAL 451
           + + + + +    +  D+ I ++G +  + G   +L
Sbjct: 478 LRLLWRK-LLWHQVFFDVAIFVIGGICSVSGFVHSL 512


>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
          Length = 435

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 88/408 (21%), Positives = 167/408 (40%), Gaps = 57/408 (13%)

Query: 32  ENVHPAGEAG-LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCM 90
           E  HPA  A  LS M  +  L+K  +G GLL  P A   AG +V    +  + ++ +   
Sbjct: 13  EKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISG 72

Query: 91  VILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFC 150
           +++L  A  +S          G+AT  G+       L   A+       FLL +  +   
Sbjct: 73  LVILGYAAAVS----------GQATYQGVV----RGLCGPAIGKLCEACFLLNLLMISV- 117

Query: 151 SVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFY--MLIILPFLILLVF--- 205
             +   + D L+++ +             +L+ TP     +Y      LP L +LV    
Sbjct: 118 -AFLRVIGDQLEKLCD------------SLLSGTPPAPQPWYADQRFTLPLLSVLVILPL 164

Query: 206 -----IQNLKVLSVFSTLANITTLGSMALIFEYIMEGI---PYPSNLPLMANWKTFLLFF 257
                I   K  S+  TLA       + + +    +G+    +PS  P  A+W +    F
Sbjct: 165 SAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESHPSLSP--ASWTSVFSVF 222

Query: 258 GTAIFTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQA 315
            T  F F+     + +   M+      ++ V  L +    ++Y L G  G++ FG++  A
Sbjct: 223 PTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSA 282

Query: 316 SITLNLP-NCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPF---------AISQVSESW 365
            + ++ P N  +    ++++++ I   Y +   +   ++  F           S +++  
Sbjct: 283 DVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPS 342

Query: 366 ALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPAL 413
            L+V + +    V +T   A+ +P L  ++S++G +SS  +  I P L
Sbjct: 343 GLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISSFFI-FIFPGL 389


>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
          Length = 456

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 91/447 (20%), Positives = 191/447 (42%), Gaps = 42/447 (9%)

Query: 14  SLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLL 73
           S+    ++ +E  S + S  +H     G+S   ++ +L+   +G+G+LGL   + N G+ 
Sbjct: 17  SVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVF 76

Query: 74  VGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVW 133
                LL + +L  + + +L      LS  +Q    +Y +  ++           A  + 
Sbjct: 77  GFSFLLLTVALLASYSVHLL------LSMCIQTAVTSYEDLGLF-----------AFGLP 119

Query: 134 GRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREI--LTLTPILDIRF 191
           G+  V+  ++I  +G  S Y + +   L   + +  +T +  +   +   TL  I+ +  
Sbjct: 120 GKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAE-FLTGDYSRYWYLDGQTLLIIICVGI 178

Query: 192 -YMLIILPFLILLVFIQNLK-VLSVFSTLANITTLGSM--ALIFEYIMEGIPYPSNL--- 244
            + L +LP +  L +  +L     +F  L  I    S+   L   Y+ +G    SN+   
Sbjct: 179 VFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQI-SNVTDD 237

Query: 245 --PLMANW-KTFLLFFGTAIFTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYI 299
             P + ++ K       T  F+F     +LP+  +++ P  ++   V    +++  ++Y 
Sbjct: 238 CKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYF 297

Query: 300 LLGTLGYMKFGSDTQASI----TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPA-EIII 354
           +    GY+ F    ++ +    +  L +  +  +VKL     +  T  L  H PA + + 
Sbjct: 298 ISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPL-IHFPARKAVT 356

Query: 355 PFAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALL 414
               S    SW     +++  AL  +  + AI +P +  V  +VG+ +S+ L  I P L 
Sbjct: 357 MMFFSNFPFSWIRHFLITL--ALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLF 414

Query: 415 EIVIFYSEDMSCVTIAKDIMISIVGLL 441
            + +   + +S   +   +++ I G+L
Sbjct: 415 YLKLSREDFLSWKKLGAFVLL-IFGIL 440


>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
           sapiens]
          Length = 1119

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 72/390 (18%), Positives = 151/390 (38%), Gaps = 43/390 (11%)

Query: 40  AGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQH 99
           A  S    + +++   +G  +L +P   K  G+++G + L+    +T    + L+  A  
Sbjct: 4   AAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASL 63

Query: 100 LSQRLQK--TFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLG--FCSVYFM 155
             +R      F  YG+A    +ET     +    +      +F +VI  LG  F +  F 
Sbjct: 64  SKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCI------AFYVVIGDLGSNFFARLFG 117

Query: 156 FMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVF 215
           F      +M     V+  I  P   L    +  I+ +  + L F  + +F+       V 
Sbjct: 118 FQVGGTFRMFLLFAVSLCIVLPLS-LQRNMMASIQSFSAMALLFYTVFMFV------IVL 170

Query: 216 STLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKN 275
           S+L +    G       Y+               W+           +F     VLP  +
Sbjct: 171 SSLKHGLFSGQWLRRVSYV--------------RWEGVFRCIPIFGMSFACQSQVLPTYD 216

Query: 276 QMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLM 333
            +  P  +  S +    +++V   Y+++G  GY+ F   T  ++ ++ P+  + + +++ 
Sbjct: 217 SLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVG 276

Query: 334 YSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVD---------LSVRSALVCLTCVS 384
           + + +   + +   +P    +   + +  +    F            ++  ++V  T V 
Sbjct: 277 FMMSVAVGFPMMI-LPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVG 335

Query: 385 AILIPRLDLVISLVGSVSSSALALIIPALL 414
            ILIP ++ ++ L G+   S +  I PAL+
Sbjct: 336 GILIPNVETILGLTGATMGSLICFICPALI 365


>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
           sapiens]
          Length = 780

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 72/390 (18%), Positives = 151/390 (38%), Gaps = 43/390 (11%)

Query: 40  AGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQH 99
           A  S    + +++   +G  +L +P   K  G+++G + L+    +T    + L+  A  
Sbjct: 4   AAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASL 63

Query: 100 LSQRLQK--TFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLG--FCSVYFM 155
             +R      F  YG+A    +ET     +    +      +F +VI  LG  F +  F 
Sbjct: 64  SKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCI------AFYVVIGDLGSNFFARLFG 117

Query: 156 FMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVF 215
           F      +M     V+  I  P   L    +  I+ +  + L F  + +F+       V 
Sbjct: 118 FQVGGTFRMFLLFAVSLCIVLPLS-LQRNMMASIQSFSAMALLFYTVFMFV------IVL 170

Query: 216 STLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKN 275
           S+L +    G       Y+               W+           +F     VLP  +
Sbjct: 171 SSLKHGLFSGQWLRRVSYV--------------RWEGVFRCIPIFGMSFACQSQVLPTYD 216

Query: 276 QMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLM 333
            +  P  +  S +    +++V   Y+++G  GY+ F   T  ++ ++ P+  + + +++ 
Sbjct: 217 SLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVG 276

Query: 334 YSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVD---------LSVRSALVCLTCVS 384
           + + +   + +   +P    +   + +  +    F            ++  ++V  T V 
Sbjct: 277 FMMSVAVGFPMMI-LPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVG 335

Query: 385 AILIPRLDLVISLVGSVSSSALALIIPALL 414
            ILIP ++ ++ L G+   S +  I PAL+
Sbjct: 336 GILIPNVETILGLTGATMGSLICFICPALI 365


>gi|117168277 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 81/423 (19%), Positives = 164/423 (38%), Gaps = 51/423 (12%)

Query: 21  SPSESSSSITSENVHPA-------GEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLL 73
           S  ES  S+T+ ++          G   L M  ++ +L    +G+G+LGL  A+ N G+L
Sbjct: 45  SDRESRRSLTNSHLEKKKCDEYIPGTTSLGM--SVFNLSNAIMGSGILGLAFALANTGIL 102

Query: 74  VGPVSLLAIGVLTVHCMVILLNCAQHLSQRL-----QKTFVNYGEATMYGLETCPNTWLR 128
           +  V L ++ +L+++ + +LL C++     +     ++ F   G+  ++G  +  NT   
Sbjct: 103 LFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNT--- 159

Query: 129 AHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILD 188
                G       +V  +L     + M   +          V   I     IL L  + +
Sbjct: 160 -----GAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKN 214

Query: 189 IRF------YMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSM---ALIFEYIMEGIP 239
           + +      + L  + F +++V  +  ++  +   L +  +  S        +Y+     
Sbjct: 215 LGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSK 274

Query: 240 YPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQ--FSFVLYLGMSIVIIL 297
               LP +A             F F     VLP+ +++K   Q     V  +    + ++
Sbjct: 275 TVYALPTIA-------------FAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVM 321

Query: 298 YILLGTLGYMKFGSDTQASI--TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIP 355
           Y L    GY+ F  + Q+ +       +  L  +V+L   + +  T  + F      +  
Sbjct: 322 YFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFE 381

Query: 356 FAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLE 415
            A       + L     V   L+ +  +  I IP +  +  +VG  S++ L  I+P+ L 
Sbjct: 382 LA---KKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLY 438

Query: 416 IVI 418
           + I
Sbjct: 439 LKI 441


>gi|117168275 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 81/423 (19%), Positives = 164/423 (38%), Gaps = 51/423 (12%)

Query: 21  SPSESSSSITSENVHPA-------GEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLL 73
           S  ES  S+T+ ++          G   L M  ++ +L    +G+G+LGL  A+ N G+L
Sbjct: 45  SDRESRRSLTNSHLEKKKCDEYIPGTTSLGM--SVFNLSNAIMGSGILGLAFALANTGIL 102

Query: 74  VGPVSLLAIGVLTVHCMVILLNCAQHLSQRL-----QKTFVNYGEATMYGLETCPNTWLR 128
           +  V L ++ +L+++ + +LL C++     +     ++ F   G+  ++G  +  NT   
Sbjct: 103 LFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNT--- 159

Query: 129 AHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILD 188
                G       +V  +L     + M   +          V   I     IL L  + +
Sbjct: 160 -----GAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKN 214

Query: 189 IRF------YMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSM---ALIFEYIMEGIP 239
           + +      + L  + F +++V  +  ++  +   L +  +  S        +Y+     
Sbjct: 215 LGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSK 274

Query: 240 YPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQ--FSFVLYLGMSIVIIL 297
               LP +A             F F     VLP+ +++K   Q     V  +    + ++
Sbjct: 275 TVYALPTIA-------------FAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVM 321

Query: 298 YILLGTLGYMKFGSDTQASI--TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIP 355
           Y L    GY+ F  + Q+ +       +  L  +V+L   + +  T  + F      +  
Sbjct: 322 YFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFE 381

Query: 356 FAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLE 415
            A       + L     V   L+ +  +  I IP +  +  +VG  S++ L  I+P+ L 
Sbjct: 382 LA---KKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLY 438

Query: 416 IVI 418
           + I
Sbjct: 439 LKI 441


>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
          Length = 472

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 98/435 (22%), Positives = 178/435 (40%), Gaps = 57/435 (13%)

Query: 39  EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQ 98
           E   S   ++ +L    +G+G+LGL  A+ + G++     LL I +L+ + + +LL CA 
Sbjct: 45  EGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAG 104

Query: 99  HLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMA 158
                            + G+        RA    G+  V+ ++ +  +G  S Y   + 
Sbjct: 105 -----------------IAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIK 147

Query: 159 DNLQQMVEKAHVTSNICQPREILTLTP-ILDIRFYMLIILPFLIL-----LVFIQNLKVL 212
             L  ++     T     P     L   +L I   +LIILP  ++     L +   L + 
Sbjct: 148 SELPLVIG----TFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLT 203

Query: 213 SVFSTLANIT----TLGSMALIFEYIME-----GIPYPS-NLPLMANWKTF--LLFFGTA 260
            +   L ++      LG      E  ME     G+P    N    A   T    + +   
Sbjct: 204 CMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVP 263

Query: 261 IFTFEGV--GMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQAS 316
           I  F  V    VLP+  ++  P  ++   V  + +  +  +Y L  T GY+ F S  +A 
Sbjct: 264 IMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAE 323

Query: 317 ITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEII-IPFAISQV-----SESWALFVD 370
           + L++ +    Q   L+  + +    A+   VP  +  I  A+ Q+     + SW   V 
Sbjct: 324 M-LHMYS----QKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVA 378

Query: 371 LSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIA 430
           +++   L+ L  V  I +P +  +  ++GS S+ +L  I+P++  + I  SE    ++  
Sbjct: 379 IAL--ILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWP 436

Query: 431 KDIMISIVGLLGCIF 445
           K I     G+LG +F
Sbjct: 437 K-IQALCFGVLGVLF 450


>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
          Length = 462

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 93/446 (20%), Positives = 169/446 (37%), Gaps = 57/446 (12%)

Query: 4   LGRDYNSELNSLDNGP-----QSPSESSSSITSENVHPAG--EAGLSMMQTLIHLLKCNI 56
           +  DY+    S D G      QSP   ++  +     P G      S +  +  ++   +
Sbjct: 6   INNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIVVNACL 65

Query: 57  GTGLLGLPLAIKNAGLLVGPVSL-LAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEAT 115
           G GLL  P A   AG +   ++L + + V  +  +VIL  C+Q  ++R  +  V      
Sbjct: 66  GAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVV------ 119

Query: 116 MYGLETCPNTWLRAHAVWGRYT---VSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTS 172
                     W    AV G+ T       + +   G C  + + + D   +++       
Sbjct: 120 ----------W----AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIA------ 159

Query: 173 NICQPREILTLTPILDIRFYMLIILPFLILLVF-----IQNLKVLSVFSTLANITTLGSM 227
            +          P    R + + +  FL +L       I   K  S  S +   T   + 
Sbjct: 160 -VMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVG--TWYVTA 216

Query: 228 ALIFEYIMEGIPY-PSN-LPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSF 285
            +I +YI       P N L   A+W        T  F F+     +P+ N M+ P+  ++
Sbjct: 217 IVIIKYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTW 276

Query: 286 --VLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSI-GIFFTY 342
             V+   M I + +Y+  G  G++ FG+     + L+ P+  +  +V   + I  +  +Y
Sbjct: 277 GGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSY 336

Query: 343 ALQFHVPAEII----IPFAISQVSESWALFVDLSVRSALV--CLTCVSAILIPRLDLVIS 396
            +       ++    + +    V E         V   LV   LT + A+ IP +  VIS
Sbjct: 337 PILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVIS 396

Query: 397 LVGSVSSSALALIIPALLEIVIFYSE 422
           ++G + ++    + P L  I    SE
Sbjct: 397 VIGGL-AACFIFVFPGLCLIQAKLSE 421


>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
          Length = 504

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 78/423 (18%), Positives = 163/423 (38%), Gaps = 65/423 (15%)

Query: 39  EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQ 98
           E   S   ++ +L    +G+G+LGL  A+ N G+++    L A+ +L+ + + +LL    
Sbjct: 63  EGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLK--- 119

Query: 99  HLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMA 158
                          + + G+        RA    G+   +  + +  +G  S Y   + 
Sbjct: 120 --------------SSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIK 165

Query: 159 D----------NLQQMVEKAHVTSN----ICQPREILTLTPILDIRF------YMLIILP 198
                      NL++     ++  N    +     IL L  +  + +      + L  + 
Sbjct: 166 SELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMV 225

Query: 199 FLILLVFIQNLKVLSVFSTLANITT--LGSMALIFEYIMEGIPYPSNLPLMANWKTFLLF 256
           F ++ V  +   V        N TT     + ++ E +   +   ++     ++  F L 
Sbjct: 226 FFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSY--FTLN 283

Query: 257 FGTAI------FTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMK 308
             TA       F F     VLP+  ++K P  ++   +  L ++++ I+Y L    GY+ 
Sbjct: 284 SQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLT 343

Query: 309 FGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPF--AISQV----- 361
           F +  ++ +         +  + L   + +     L   +   ++ P   AI Q+     
Sbjct: 344 FYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPI---VLFPVRRAIQQMLFPNQ 400

Query: 362 SESWALFVDLSVRSALVCLTCVSAILI--PRLDLVISLVGSVSSSALALIIPALLEIVIF 419
             SW   V ++V      LTC++ ++I  P +  +  ++G+ S+  L  I PA+    I 
Sbjct: 401 EFSWLRHVLIAVG----LLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIM 456

Query: 420 YSE 422
            +E
Sbjct: 457 PTE 459


>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
          Length = 506

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 80/448 (17%), Positives = 165/448 (36%), Gaps = 84/448 (18%)

Query: 43  SMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQ 102
           S   ++ +L    +G+G+LGL  A+ N G+ +  + L  + + +++ + +LL  A     
Sbjct: 72  SFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTA----- 126

Query: 103 RLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQ 162
                  N G + +Y          +A  + G+   S  + +  +G  S Y   +   L 
Sbjct: 127 -------NEGGSLLY-----EQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYEL- 173

Query: 163 QMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANI- 221
                         P  I  LT I D      +   +L+LLV +  +  LS+F  L  + 
Sbjct: 174 --------------PLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLG 219

Query: 222 --TTLGSMALIFEYIME-----GIPYPSNLPLMAN------------------------- 249
             + L  + ++F  I+       +P P    L+ N                         
Sbjct: 220 YTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTEND 279

Query: 250 -WKTFLLFFGTA--------IFTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILY 298
             +     F +         IF+F     VLP+  ++K    ++   V  +    + ++Y
Sbjct: 280 SCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMY 339

Query: 299 ILLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAI 358
           +L    GY+ F    ++ +     +      + L+  + +     L   V   +I P   
Sbjct: 340 LLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPV---VIFPIRS 396

Query: 359 SQV-----SESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPAL 413
           S       S+ ++ +    +  +++  T +  I +P +  +   +G+ ++S L  I+P+ 
Sbjct: 397 SVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSA 456

Query: 414 LEIVIFYSEDMSCVTIAKDIMISIVGLL 441
             I +   E M  V     +   + G+L
Sbjct: 457 FYIKLVKKEPMKSVQKIGALFFLLSGVL 484


>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 37/190 (19%), Positives = 79/190 (41%), Gaps = 16/190 (8%)

Query: 261 IFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSI--VIILYILLGTLGYMKFGSDTQASI- 317
           +F F     VLP+ +++K   +        +SI  ++++Y+L    GY+ F  + +  + 
Sbjct: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399

Query: 318 -------TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVD 370
                  TL++P       V+L   + +  T  +        +I     +   SW     
Sbjct: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRH-- 453

Query: 371 LSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIA 430
             + + L+ L  V  IL+P +  +   +G+ S++ L  I+PA+  + +   E        
Sbjct: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513

Query: 431 KDIMISIVGL 440
             ++  +VG+
Sbjct: 514 GALIFLVVGI 523



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 35  HPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILL 94
           H  G     M     +L    +G+G+LGL  A+ N G+++  + LLA+ +L+++ + +LL
Sbjct: 70  HHPGTTSFGMSS--FNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLL 127

Query: 95  NCAQ 98
             A+
Sbjct: 128 KTAK 131


>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 37/190 (19%), Positives = 79/190 (41%), Gaps = 16/190 (8%)

Query: 261 IFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSI--VIILYILLGTLGYMKFGSDTQASI- 317
           +F F     VLP+ +++K   +        +SI  ++++Y+L    GY+ F  + +  + 
Sbjct: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399

Query: 318 -------TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVD 370
                  TL++P       V+L   + +  T  +        +I     +   SW     
Sbjct: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRH-- 453

Query: 371 LSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIA 430
             + + L+ L  V  IL+P +  +   +G+ S++ L  I+PA+  + +   E        
Sbjct: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513

Query: 431 KDIMISIVGL 440
             ++  +VG+
Sbjct: 514 GALIFLVVGI 523



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 35  HPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILL 94
           H  G     M     +L    +G+G+LGL  A+ N G+++  + LLA+ +L+++ + +LL
Sbjct: 70  HHPGTTSFGMSS--FNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLL 127

Query: 95  NCAQ 98
             A+
Sbjct: 128 KTAK 131


>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
          Length = 561

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 26/119 (21%), Positives = 54/119 (45%), Gaps = 20/119 (16%)

Query: 47  TLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQK 106
           T+  +    +GT +L +P  IK AG   G   ++ +G+LT++C      C + +  R   
Sbjct: 122 TIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYC------CYRVVKSR--- 172

Query: 107 TFVNYGEATMYGLETC----PNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNL 161
                    M+ L+T     P+        +G+++     +++ +G   VY++ M++ L
Sbjct: 173 -------TMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFL 224


>gi|53828674 olfactory receptor, family 13, subfamily C, member 4
           [Homo sapiens]
          Length = 318

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 61/308 (19%), Positives = 127/308 (41%), Gaps = 56/308 (18%)

Query: 185 PILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITT---LGSMALIFEYIMEGIPYP 241
           P L+I F+ LI++ ++++L+    L + S+  +  ++     LG+++ + +        P
Sbjct: 21  PKLEIIFFALILVMYVVILIGNGVLIIASILDSRLHMPMYFFLGNLSFL-DICYTTSSIP 79

Query: 242 SNLPLMANWKTFLLFFGTAIFTFEGVGMVLP---LKNQMKHPQQFSFVLYLGMSIVI--I 296
           S L  + + K  + F G A+  F G  M      L   M   +  +    L   I++  +
Sbjct: 80  STLVSLISKKRNISFSGCAVQMFFGFAMGSTECFLLGMMAFDRYVAICNPLRYPIIMNKV 139

Query: 297 LYILLGTLGYMKFG--SDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIII 354
           +Y+LL ++ ++  G  S  Q S+ +  P C                   +  H   EI+ 
Sbjct: 140 VYVLLTSVSWLSGGINSTVQTSLAMRWPFCG----------------NNIINHFLCEIL- 182

Query: 355 PFAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVG--------------- 399
             A+ +++ S     D+SV    + ++ ++ +++P L +  S +                
Sbjct: 183 --AVLKLACS-----DISVNIVTLAVSNIAFLVLPLLVIFFSYMFILYTILRTNSATGRH 235

Query: 400 ---SVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQ 456
              S  S+ L ++I     I   Y++  S   + KD + +  GL+   +G    +     
Sbjct: 236 KAFSTCSAHLTVVIIFYGTIFFMYAKPKSQDLLGKDNLQATEGLVSMFYGVVTPML---N 292

Query: 457 PISHSMAN 464
           PI +S+ N
Sbjct: 293 PIIYSLRN 300


>gi|53828744 olfactory receptor, family 11, subfamily G, member 2
           [Homo sapiens]
          Length = 345

 Score = 32.3 bits (72), Expect = 0.95
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 8/78 (10%)

Query: 147 LGFCSVYFMFMADNLQQM--VEKAHVTSNICQPREILTLT----PILDIRFYMLIILPFL 200
           LGF  ++F+    N+ QM       +   +C P  +LTLT    P++++ F +L  LP  
Sbjct: 189 LGF--IWFLIPIVNISQMSFCGSRIIDHFLCDPAPLLTLTCKKGPVIELVFSVLSPLPVF 246

Query: 201 ILLVFIQNLKVLSVFSTL 218
           +L +FI     L V + L
Sbjct: 247 MLFLFIVGSYALVVRAVL 264


>gi|116812579 transmembrane BAX inhibitor motif containing 4 [Homo
           sapiens]
          Length = 238

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 11/88 (12%)

Query: 224 LGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQF 283
           LGS+ LIF  I+    YP NL L+  +          + TF  V ++L            
Sbjct: 78  LGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQ----------- 126

Query: 284 SFVLYLGMSIVIILYILLGTLGYMKFGS 311
           +F+L   +   + +Y L     + KFG+
Sbjct: 127 AFILTTTVFFGLTVYTLQSKKDFSKFGA 154


>gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo
           sapiens]
          Length = 320

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 14/38 (36%), Positives = 22/38 (57%)

Query: 357 AISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLV 394
           +  +  E+WA F DL V + LVC   + +IL+  L +V
Sbjct: 163 SFEKTKETWAFFEDLYVYAVLVCCVGILSILLFMLVIV 200


>gi|4757956 cadherin 16 precursor [Homo sapiens]
          Length = 829

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 339 FFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVCLTCVSAI-----LIPRLDL 393
           + T AL +  P E IIP  +S  ++ W L V + V    V   C+  +     +  +L  
Sbjct: 727 YLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGMPTKLSA 786

Query: 394 VISLVGSVSSSALALII 410
           V  LVG++ +  + LI+
Sbjct: 787 VGILVGTLVAIGIFLIL 803


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,789,342
Number of Sequences: 37866
Number of extensions: 628371
Number of successful extensions: 2194
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2151
Number of HSP's gapped (non-prelim): 37
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.