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Search of human proteins with 222352127
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222352127 sidekick 2 [Homo sapiens]
(2172 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222352127 sidekick 2 [Homo sapiens] 4389 0.0
gi|119220552 sidekick 1 [Homo sapiens] 2611 0.0
gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken) ... 582 e-165
gi|75709184 contactin 3 [Homo sapiens] 331 5e-90
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 330 7e-90
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 323 1e-87
gi|7657361 contactin 6 [Homo sapiens] 311 6e-84
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 310 1e-83
gi|4827022 contactin 2 precursor [Homo sapiens] 282 2e-75
gi|28373129 contactin 5 isoform short [Homo sapiens] 275 4e-73
gi|7657359 contactin 5 isoform long [Homo sapiens] 274 6e-73
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 270 1e-71
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 264 8e-70
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 264 8e-70
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 264 8e-70
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 260 9e-69
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 251 5e-66
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 248 5e-65
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 248 6e-65
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 248 6e-65
gi|110349719 titin isoform N2-A [Homo sapiens] 246 1e-64
gi|110349717 titin isoform novex-2 [Homo sapiens] 246 1e-64
gi|110349713 titin isoform novex-1 [Homo sapiens] 246 1e-64
gi|110349715 titin isoform N2-B [Homo sapiens] 246 1e-64
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 245 3e-64
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 245 4e-64
gi|157311649 neogenin homolog 1 [Homo sapiens] 243 2e-63
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 241 7e-63
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 240 1e-62
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 239 2e-62
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 4389 bits (11384), Expect = 0.0
Identities = 2172/2172 (100%), Positives = 2172/2172 (100%)
Query: 1 MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKW 60
MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKW
Sbjct: 1 MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKW 60
Query: 61 LHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEK 120
LHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEK
Sbjct: 61 LHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEK 120
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR 180
HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR
Sbjct: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR 180
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN 240
YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN
Sbjct: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN 240
Query: 241 ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA 300
ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA
Sbjct: 241 ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA 300
Query: 301 YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR
Sbjct: 301 YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV
Sbjct: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS
Sbjct: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
Query: 481 RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT
Sbjct: 481 RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
Query: 541 ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL
Sbjct: 541 ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
Query: 601 STVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARS 660
STVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARS
Sbjct: 601 STVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARS 660
Query: 661 YQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQN 720
YQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQN
Sbjct: 661 YQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQN 720
Query: 721 GILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSS 780
GILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSS
Sbjct: 721 GILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSS 780
Query: 781 KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEV 840
KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEV
Sbjct: 781 KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEV 840
Query: 841 TMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGH 900
TMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGH
Sbjct: 841 TMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGH 900
Query: 901 LSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTA 960
LSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTA
Sbjct: 901 LSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTA 960
Query: 961 LTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGK 1020
LTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGK
Sbjct: 961 LTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGK 1020
Query: 1021 TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS 1080
TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS
Sbjct: 1021 TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS 1080
Query: 1081 PPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR 1140
PPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR
Sbjct: 1081 PPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR 1140
Query: 1141 SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200
SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS
Sbjct: 1141 SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200
Query: 1201 SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRS 1260
SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRS
Sbjct: 1201 SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRS 1260
Query: 1261 AQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI 1320
AQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI
Sbjct: 1261 AQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI 1320
Query: 1321 WQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTR 1380
WQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTR
Sbjct: 1321 WQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTR 1380
Query: 1381 KGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTR 1440
KGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTR
Sbjct: 1381 KGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTR 1440
Query: 1441 ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA
Sbjct: 1441 ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
Query: 1501 PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 1560
PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP
Sbjct: 1501 PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 1560
Query: 1561 GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE 1620
GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE
Sbjct: 1561 GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE 1620
Query: 1621 AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFL 1680
AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFL
Sbjct: 1621 AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFL 1680
Query: 1681 AENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSV 1740
AENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSV
Sbjct: 1681 AENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSV 1740
Query: 1741 NVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFR 1800
NVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFR
Sbjct: 1741 NVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFR 1800
Query: 1801 IRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860
IRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE
Sbjct: 1801 IRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860
Query: 1861 ARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPA 1920
ARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPA
Sbjct: 1861 ARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPA 1920
Query: 1921 QKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEM 1980
QKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEM
Sbjct: 1921 QKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEM 1980
Query: 1981 MSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAE 2040
MSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAE
Sbjct: 1981 MSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAE 2040
Query: 2041 SSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAY 2100
SSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAY
Sbjct: 2041 SSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAY 2100
Query: 2101 SYTESDSGEPDHTTVTNSTSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPG 2160
SYTESDSGEPDHTTVTNSTSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPG
Sbjct: 2101 SYTESDSGEPDHTTVTNSTSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPG 2160
Query: 2161 SRAPIAGFSSFV 2172
SRAPIAGFSSFV
Sbjct: 2161 SRAPIAGFSSFV 2172
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 2611 bits (6767), Expect = 0.0
Identities = 1274/2172 (58%), Positives = 1636/2172 (75%), Gaps = 48/2172 (2%)
Query: 7 WTLLAL--HQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNN 64
W LLAL H +RA AQDDV+PYFKTEP Q+HLEGNRLVLTC+AEGSWPLEFKW+ ++
Sbjct: 84 WALLALQLHLLRAL-AQDDVAPYFKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDD 142
Query: 65 RELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSV 124
ELT +S EY+Y+I SL + AGFYRC+VRNRMGALLQR++EVQVAYMGSF + ++ ++V
Sbjct: 143 SELTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTV 202
Query: 125 SHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQ 184
S G AA++ I S+P+PQVTWFR+G KI PS+RIAITLEN LVIL+T DAG YYVQ
Sbjct: 203 SQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLVILATTTSDAGAYYVQ 262
Query: 185 AVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPL 244
AVN+KNG+NKTS I L++ G + +APTI++PP N SVVAG+SE TLEC+A+ARP+
Sbjct: 263 AVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPV 322
Query: 245 IKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSV 304
L + WK++GV ++ G+ RRLTI NPT +D G Y CEA L S+ A+L +
Sbjct: 323 EDLSVTWKRNGVRITSGLHSFGRRLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFI 382
Query: 305 LEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG 364
+EPP F EPE I+AE+E+ VDI CQA GVP P++ WYKDA + + R++ GG
Sbjct: 383 IEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG 442
Query: 365 LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACE 424
L+I L P+D+G+FQCFA N GE+QT TYL VT+IAP T+ P+D+TV DGM+ +L CE
Sbjct: 443 LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCE 502
Query: 425 TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
SGAP+PAITW++ ILASGSV++PRF LESG L I+P I DAG YTC A N+ G
Sbjct: 503 VSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSL 562
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHP 544
ASA L VW RT I PP+D VIKGT A++ CG THDPRV++RY+W+KD L S
Sbjct: 563 NASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTS 622
Query: 545 RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVE 604
RI ++++GSL ISQTWSGDIG Y+C ++S GGNDSR A L V +LPH+P++ + + ++
Sbjct: 623 RIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPNSSH 682
Query: 605 RRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFR 664
A+ L+W +PFDGNSP++ YI+E+SENN+PW V L++V P+ T VTV GL PAR+YQFR
Sbjct: 683 SHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFR 742
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILK 724
+CAVN+VG+GQ+S +T R+ LPEEPP+APP+N++ASGRTNQSIM+QWQPPPE+ NG+L+
Sbjct: 743 VCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLR 802
Query: 725 GYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTE 784
GYI+RY LAGLP YQ +NIT +VN L+ DLIIWT YEI+VAAYN AGLGV+S VTE
Sbjct: 803 GYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTE 862
Query: 785 WTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT 844
+TLQGVPT PP NV EA NSTTI+F WN P QFINGINQGYKL+AW + E VT+VT
Sbjct: 863 YTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVT 922
Query: 845 ARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFS 904
P+F +H G ++ LKKFT YFTSVLCFTTPGDGP STPQLV T ED PG VGHLSF+
Sbjct: 923 IAPDFH-GVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFT 981
Query: 905 EILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTY 964
EILDTSLKVSWQEP EKNGI+TGY+ISWE Y R ++R+TH L + T EY++ GL++LTTY
Sbjct: 982 EILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTY 1041
Query: 965 TIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSIS 1024
TI+VAA+T+ G G V++STISSGVPP+LPG P+NL ISNI PRS TLQFRPGYDGKTSIS
Sbjct: 1042 TIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSIS 1101
Query: 1025 RWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQ 1084
RW+VE QVG +G+ EEW+ +++ NEPDA+ +E+P+L P+T Y FRM+QVNIVG SP S
Sbjct: 1102 RWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSP 1161
Query: 1085 PSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
SR IQTLQAPPD+AP +V++RTASETSL LRW+PLP+ +YNGNPESVGY+IKY RSD
Sbjct: 1162 SSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQ 1221
Query: 1145 GKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPT 1204
++ VV DR+ER++TIE+LEEW EY +Q+QAFNA+G+GPWS+ V GRTRESVPS+ P
Sbjct: 1222 SSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPE 1281
Query: 1205 NVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLT 1264
NVSA A +S+ +L+ W+ VPE D+NGL+LGYK++++ KD D +PR +V GN ++SA L
Sbjct: 1282 NVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLA 1341
Query: 1265 GLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
GL K+VLYE+QVLAFTRIG+G PS P ILERT DD PGPP+ ++FPEVR TSVR++WQPP
Sbjct: 1342 GLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPP 1401
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
PNGIIL YQI +RL +++ +T T + + RQ+TAT L PES Y+FR++A+TR+GWG
Sbjct: 1402 EEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWG 1461
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPS 1444
E EA V+TTEKR+RP PP +V Q +V ARS+ L W PGSDG SP+RY+T+Q RELP
Sbjct: 1462 EPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPR 1521
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEA 1504
G W +S+S+SH A++ +VDRL+PFTSYK R+KATNDIGDS+FS E+E++TTLQ P E
Sbjct: 1522 GEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEP 1581
Query: 1505 PTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATW 1564
P +S TPHTT+SVLI+WQPP ++ +NG+L G+RI YREL YE G + + NP A
Sbjct: 1582 PGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALH 1641
Query: 1565 AELTSMYSMRNLSRPSL-TQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVP 1623
AELT+ S + ++ S T EL +L K+RRYE+ M+ YN +GE P+S P EVFVGEA P
Sbjct: 1642 AELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAP 1701
Query: 1624 TAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAEN 1683
AP+NV V TA+QL+VTW+PPP +SQNG+IQGYKIY+WEA N TE++K LFL E
Sbjct: 1702 AMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEP 1761
Query: 1684 SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVS 1743
V+LKNLT +T Y+VS++AFNAAGDGP+S P QG+T QAAP APS + FSE+T+T++NVS
Sbjct: 1762 VVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVS 1821
Query: 1744 WEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA 1803
W P NGIL+GYR+VYEP +PV GVSK+VTV+V+GN WLKV+DL +GVTY FR++A
Sbjct: 1822 WGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA 1881
Query: 1804 KTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARP 1863
+T TYGPE++AN+T GP EG+PG P ++ + +S + + W+ G G P T YVIEARP
Sbjct: 1882 RTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARP 1941
Query: 1864 SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKA 1923
SDEGLWD+ +KDIP+ +SYT S+D L+ GV+Y+FRV+AVN+ G+G PS+PS +V AQ
Sbjct: 1942 SDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVE 2001
Query: 1924 NPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEMMSL 1983
PFYEEWWFL+V+AL LI ILL+VF L++ GQ+KKY K +G G E ++L
Sbjct: 2002 APFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKY-KNCSTG----KGISTMEESVTL 2056
Query: 1984 DESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDV-TKYNDLIPAESS 2042
D F ALEL++R L+VK++F +KNG TRSPPRPSPG LHYSDED+ KYN + ES
Sbjct: 2057 DNGGFAALELSSRHLNVKSTFSKKNG--TRSPPRPSPGGLHYSDEDICNKYNGAVLTESV 2114
Query: 2043 SLTEKPSEISDSQGSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRA--QAY 2100
SL EK ++ S+S+ +DS+YE + HSFVNHY+SDPTYYNSW+R+ +G + A +
Sbjct: 2115 SLKEKSADASESEATDSDYE---DALPKHSFVNHYMSDPTYYNSWKRRAQGRAPAPHRYE 2171
Query: 2101 SYTESDSGEPDHTTVTNSTSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPG 2160
+ S++G H +T ++ G ++ P PG
Sbjct: 2172 AVAGSEAGAQLHPVITTQSA---GGVYTP---------------------------AGPG 2201
Query: 2161 SRAPIAGFSSFV 2172
+R P+ GFSSFV
Sbjct: 2202 ARTPLTGFSSFV 2213
>gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken)
[Homo sapiens]
Length = 399
Score = 582 bits (1500), Expect = e-165
Identities = 295/314 (93%), Positives = 299/314 (95%), Gaps = 9/314 (2%)
Query: 242 RPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 301
RPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY
Sbjct: 54 RPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 113
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN
Sbjct: 114 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 173
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVL 421
DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVL
Sbjct: 174 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVL 233
Query: 422 ACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSR 481
ACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSR
Sbjct: 234 ACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSR 293
Query: 482 GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTE 541
GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIR + + GA G
Sbjct: 294 GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRQL--RPGAPSGGH 351
Query: 542 -------SHPRIRL 548
SHP++RL
Sbjct: 352 WTYDSLYSHPQMRL 365
Score = 89.4 bits (220), Expect = 4e-17
Identities = 78/254 (30%), Positives = 107/254 (42%), Gaps = 17/254 (6%)
Query: 340 ITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFA---RNAAGEVQTSTYLA 396
I W KD ++ R+ L I D G ++C A ++ V YL+
Sbjct: 61 IIWKKDGVLLSGGISDHNRR-----LTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLS 115
Query: 397 VTSIAPNITRGPLDSTVIDGMSVV-LACETSGAPRPAITWQKGERILASGSVQLPRFTPL 455
V P + P + VV + C+ G P P+ITW K ++ +L RF
Sbjct: 116 VLE-PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVE--KLTRFRQR 172
Query: 456 ESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA-RTRITKPPQDQSVIKGTQAS 514
G L IS D G + C A N+ G + S L V + IT+ P D +VI G
Sbjct: 173 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 232
Query: 515 MVCGVTHDPRVTIRYIWEKDGATL--GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVI 572
+ C + PR I W+K L G+ PR +GSL IS T D GTYTC
Sbjct: 233 LACETSGAPRPAIT--WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLAT 290
Query: 573 SAGGNDSRSAHLRV 586
++ G D SA L V
Sbjct: 291 NSRGVDEASADLVV 304
Score = 46.2 bits (108), Expect = 3e-04
Identities = 61/249 (24%), Positives = 100/249 (40%), Gaps = 27/249 (10%)
Query: 75 RYMITSLDRTHAGFYRC--IVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVI 132
R I + + AG+Y C ++R+ + R + V F + + + E V
Sbjct: 80 RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVD 139
Query: 133 RAPRIASFPQPQVTWFRDGR--KIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKN 190
+ P P +TW++D ++ +R + L I V D G + A N
Sbjct: 140 IPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARN-AA 198
Query: 191 GDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHII 250
G+ +TS + +T IAP I P +++V+ G S V L C + P + I
Sbjct: 199 GEVQTSTYLAVT---------SIAPNITRGPLDSTVIDGMS-VVLACETSGAP--RPAIT 246
Query: 251 WKK-DGVLLSGGIS------DHNRRLTIPNPTGSDAGYYECEAVLR---SSSVPSVVRGA 300
W+K + +L SG + + L I SDAG Y C A + +V A
Sbjct: 247 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 306
Query: 301 YLSVLEPPQ 309
+ +PPQ
Sbjct: 307 RTRITKPPQ 315
Score = 36.6 bits (83), Expect = 0.28
Identities = 44/164 (26%), Positives = 62/164 (37%), Gaps = 19/164 (11%)
Query: 433 ITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
I W+K +L+ G R + + PT SDAG Y C A + +V
Sbjct: 61 IIWKKDGVLLSGGISDHNRRLTIPN------PTG-SDAGYYECEAVLR---SSSVPSVVR 110
Query: 493 WARTRITKPPQ----DQSVIKGTQASMV---CGVTHDPRVTIRYIWEKDGATLGTESHPR 545
A + +PPQ + I +V C P +I W KD A + E R
Sbjct: 111 GAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTR 168
Query: 546 IRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
R +G L IS D G + C +A G S +L V +
Sbjct: 169 FRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI 212
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 331 bits (848), Expect = 5e-90
Identities = 289/1017 (28%), Positives = 454/1017 (44%), Gaps = 63/1017 (6%)
Query: 26 PYFKTEPVRT--QVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRY------- 76
P F EP + V E ++ L C A G+ ++W N ++ S+E+RY
Sbjct: 26 PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDID-MSMEHRYKLNGGNL 84
Query: 77 -MITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQ-SVSHGEAAVIRA 134
+I G Y+C N +G ++ R+ ++Q AY+ +F+ + SV G+ V+
Sbjct: 85 VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC 144
Query: 135 PRIASFPQPQVTWFRDGRK--IPPSSRIAITLENTLVILSTVAP-DAGRYYVQAVNDKNG 191
+ W + + SR ++ E + +S V P D G Y +
Sbjct: 145 GPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTN 204
Query: 192 DNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIW 251
P L + + G + P I + T A S V LEC A P+ +++ W
Sbjct: 205 ARVLGSPTPLVLRSDGVMGE-YEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQIN--W 261
Query: 252 KK-DGVLLSGGIS--DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP 308
++ DG+ S I + L IPN DAG YEC + +S +V RG +P
Sbjct: 262 RRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYEC--IAENSRGKNVARGRLTYYAKPH 319
Query: 309 --QFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ 366
Q +K+ E +E + C+A G P PS W K+ A + +E+ T Q +G L
Sbjct: 320 WVQLIKDVE----IAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERT---QIENGALT 372
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID--GMSVVLACE 424
IS L D+GMFQC A N G V +S L V + AP+ ++ P+ V G V L C+
Sbjct: 373 ISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCK 432
Query: 425 TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
+PR +W+KG+ + R + L G L I+ +DAGTYTC+A N G
Sbjct: 433 PRASPRALSSWKKGDVSVQEHE----RISLLNDGGLKIANVTKADAGTYTCMAENQFGKA 488
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTE--- 541
+ LVV TRIT P + V G + C V HDP + I + W +GA +
Sbjct: 489 NGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDG 548
Query: 542 SH-PRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
SH ++ +G L I G Y C V + + S +A L VR P PE+ +
Sbjct: 549 SHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPEN--VKV 606
Query: 601 STVERRAINLTWTKPFDGNSPLIRYILEM-SENNAPW---TVLLASVDPKATSVTVKGLV 656
+ L+W + D +SP+I Y ++ + + W T + +D K + TV L
Sbjct: 607 DEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELN 666
Query: 657 PARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPE 716
P Y+FR+ A N +G G+ S +E+V E P PP V G + ++I W P PE
Sbjct: 667 PWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPE 726
Query: 717 SHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL--EDLIIWTNYEIEVAAYNSAG 774
QNG GY++ + G+ Q +T D + E ++ ++ YE++V YN+ G
Sbjct: 727 ELQNGEGFGYVVAFRPLGVTTWIQ-TVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKG 785
Query: 775 LGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEP 834
G +S T ++ + PTV P V A + +S+ I +WN + NG GY++ W
Sbjct: 786 EGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNG 845
Query: 835 EQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDV 894
+EE + + S + GLK Y+T+V + + G GP S V T +
Sbjct: 846 GGKEESSSKMKVAGNETSAR---LRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTP 902
Query: 895 PG-PVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTL 951
P P G++ ++ DT + ++W++ E +TGY++ + ++ N +V + N T
Sbjct: 903 PSQPPGNVVWN-ATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLN--TNKTS 959
Query: 952 EYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRS 1008
V L Y IEV A T G G S+ I + + ISN+ P S
Sbjct: 960 AELV--LPIKEDYIIEVKATTDGGDG-TSSEQIRIPRITSMDARGSTSAISNVHPMS 1013
Score = 157 bits (396), Expect = 1e-37
Identities = 111/376 (29%), Positives = 175/376 (46%), Gaps = 31/376 (8%)
Query: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSAS--- 1453
R P PP V+ +++ + LSW+ G D SPV Y+IQ R S W +
Sbjct: 595 RGSPGPPEN--VKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEV 652
Query: 1454 VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH 1513
+ + V L P+ Y+FRV A+N IG E S SE + T +A P+ P+ ++
Sbjct: 653 IDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGG 712
Query: 1514 TTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSM 1573
+ + ++I W P E+ NG G+ + +R L G+ + + +P T Y
Sbjct: 713 SRSELVITWDPVPEELQNGEGFGYVVAFRPL---GVTTWIQTVVTSPD------TPRYVF 763
Query: 1574 RNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVH 1633
RN +++ + YE+++ VYN GEGP SP VF E PT AP V +
Sbjct: 764 RN-----------ESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSAN 812
Query: 1634 GATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA--ENSVKLKNLT 1691
++++++V+W P NG + GY++ +W G E + +A E S +L+ L
Sbjct: 813 SLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNG--GGKEESSSKMKVAGNETSARLRGLK 870
Query: 1692 GYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPN 1751
AY +V A+N+AG GP S T++ PS P T T V ++WE +
Sbjct: 871 SNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAME 930
Query: 1752 GILE--GYRLVYEPCS 1765
E GY++ Y S
Sbjct: 931 NESEVTGYKVFYRTSS 946
Score = 132 bits (332), Expect = 4e-30
Identities = 119/433 (27%), Positives = 189/433 (43%), Gaps = 40/433 (9%)
Query: 977 GQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV-V 1035
G S S+ + + PGPP N+ + I + L ++ G D + + + ++A+ V
Sbjct: 582 GVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSV 641
Query: 1036 GEGEEWLLIHQLSNEPDARS--MEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
G W + + D ++ V +LNP+ Y FR+ N +G PS PS K++T +
Sbjct: 642 G----WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEE 697
Query: 1094 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ 1153
A P++ P+ V+ S + L + W P+PE NG E GY + + R G + VV
Sbjct: 698 AVPEVPPSEVNGGGGSRSELVITWDPVPEELQNG--EGFGYVVAF-RPLGVTTWIQTVVT 754
Query: 1154 DRVERDYTI--EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALAT 1211
Y E + ++ Y V+V +N G GP+S + E P+ P+ VSA +
Sbjct: 755 SPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSL 814
Query: 1212 TSSSMLVRWSEVPEADRNGLVLGYKVMY-----KEKDSDTQPRFWLVEGNSSRSAQLTGL 1266
+SS + V W+ +P NG +LGY+V Y KE+ S V GN + SA+L GL
Sbjct: 815 SSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMK----VAGNET-SARLRGL 869
Query: 1267 GKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAA 1326
+ Y V A+ G G P + T P P G + T V L W+ A
Sbjct: 870 KSNLAYYTAVRAYNSAGAG-PFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKA 928
Query: 1327 ------PNGIILAYQITHRLNTTTANT--ATVEVLAPSARQYT---------ATGLKPES 1369
G + Y+ + + N NT + E++ P Y G E
Sbjct: 929 MENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSEQ 988
Query: 1370 VYLFRITAQTRKG 1382
+ + RIT+ +G
Sbjct: 989 IRIPRITSMDARG 1001
Score = 99.8 bits (247), Expect = 3e-20
Identities = 111/476 (23%), Positives = 188/476 (39%), Gaps = 53/476 (11%)
Query: 1250 FWLVEGNSS-----RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1304
F V G+SS R+ QL GKYV + G S + + PGPP
Sbjct: 551 FEKVGGSSSGDLMIRNIQLKHSGKYVCM---------VQTGVDSVSSAADLIVRGSPGPP 601
Query: 1305 MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTA---NTATVEVLAPSARQYT 1361
+ E+ T+ +L W+ + +++Y I R + T EV+ T
Sbjct: 602 ENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTAT 661
Query: 1362 ATGLKPESVYLFRITAQTRKGWGEAA-EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLL 1420
L P Y FR+ A + G GE + + V TE+ PPS V +++
Sbjct: 662 VVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSE--VNGGGGSRSELVI 719
Query: 1421 SWEPGSDGLSPVRY--YTIQTRELPSGRWALHSASVSHNASSFIV--DRLKPFTSYKFRV 1476
+W+P + L Y + R L W + + S + ++ + + P++ Y+ +V
Sbjct: 720 TWDPVPEELQNGEGFGYVVAFRPLGVTTW-IQTVVTSPDTPRYVFRNESIVPYSPYEVKV 778
Query: 1477 KATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLG 1536
N+ G+ FS + ++ + + P AP+ +S +++ + + W NG LLG
Sbjct: 779 GVYNNKGEGPFSPVT-TVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLG 837
Query: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYE 1596
+ +RY N G + M N T L L + Y
Sbjct: 838 YEVRYW----------------NGGGKEESSSKMKVAGNE-----TSARLRGLKSNLAYY 876
Query: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
+ YN+ G GP S V + P+ P NVV + AT T++ + WE ++
Sbjct: 877 TAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWN-ATDTKVLLNWEQVKAMENESEV 935
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712
GYK+++ + + N+ AE + +K Y++ V A GDG S
Sbjct: 936 TGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKE-----DYIIEVKATTDGGDGTSS 986
Score = 93.2 bits (230), Expect = 2e-18
Identities = 100/400 (25%), Positives = 169/400 (42%), Gaps = 21/400 (5%)
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG-KTLSHV--VQDRV 1156
P NV + ++T+ L W E + N +P + Y I+ G +T++ V V D
Sbjct: 601 PENVKVDEITDTTAQLSWK---EGKDNHSPV-ISYSIQARTPFSVGWQTVTTVPEVIDGK 656
Query: 1157 ERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSSS 1215
T+ +L W EY +V A N IG G P + RT E+VP P+ V+ + S
Sbjct: 657 THTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSE 716
Query: 1216 MLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYVLYEV 1274
+++ W VPE +NG GY V ++ T + + ++ R + + Y YEV
Sbjct: 717 LVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEV 776
Query: 1275 QVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQ--PPAAPNGIIL 1332
+V + G+G S + ++ P + + ++ + + W P NG +L
Sbjct: 777 KVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLL 836
Query: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
Y++ + +++ +A + GLK Y + A G G + + V
Sbjct: 837 GYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNV 896
Query: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP--GSDGLSPVRYYTIQTRELPSGRWALH 1450
TT+K QPP + D + VLL+WE + S V Y + R +
Sbjct: 897 TTKKTPPSQPPGNVVWNATDTK---VLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVL 953
Query: 1451 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
+ ++ S+ +V +K Y VKAT D GD SE+
Sbjct: 954 N---TNKTSAELVLPIKE--DYIIEVKATTDGGDGTSSEQ 988
Score = 58.2 bits (139), Expect = 9e-08
Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 1823 GAPGPP-GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
G+PGPP V + + + W G P+ Y I+AR W + +P+ +
Sbjct: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQT-VTTVPEVID 654
Query: 1882 SYTFSMDI--LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
T + + L P V Y+FRV+A N G G PS PS+ V ++A P
Sbjct: 655 GKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVP 700
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 330 bits (847), Expect = 7e-90
Identities = 352/1291 (27%), Positives = 541/1291 (41%), Gaps = 135/1291 (10%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHN--------NRELTKFSLEYRYMITSLDRTHAGFYRCI 92
G+++ L+C G+ E W N N +T + E ++ + ++ G Y+C
Sbjct: 328 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHE-NLIMDHMVKSDGGAYQCF 386
Query: 93 VRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASF------PQPQVT 146
VR L Q VQV E+G + E V A ++ P P +T
Sbjct: 387 VRKDK---LSAQDYVQVV----LEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTIT 439
Query: 147 WFRDGRKIPP--SSRIA--ITLENTLV----ILSTVAPDAGRYYVQAVNDKNGDNKTSQP 198
W D I S RI+ IT E +V I S+ D G Y A +N
Sbjct: 440 WTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTA------NNSAGVV 493
Query: 199 ITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLL 258
+ NV GPA I P KN + +AG + + C P + W K+ LL
Sbjct: 494 LYQARINVRGPAS------IRPMKNITAIAGR-DTYIHCRVIGYPYYSIK--WYKNSNLL 544
Query: 259 SGG----ISDHNRRLTIPNPTGS-DAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE 313
++N L + + D G Y C +++ S + +++V PP F+ +
Sbjct: 545 PFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQL--STSQSVHVTVKVPP-FI-Q 600
Query: 314 PERHITAEMEKVVDIPCQA-KGVPPPSITWYKDAAVVEVEK-LTRFRQRNDGGLQISGLV 371
P + + V IPC G P +ITW KD + +T L+IS L
Sbjct: 601 PFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLS 660
Query: 372 PDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRP 431
G + C ARN A V+ + L V + P P D I G +V+L C G P P
Sbjct: 661 LMHNGNYTCIARNEAAAVEHQSQLIVR-VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVP 719
Query: 432 AITWQ--KGERILASGSVQLP-RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA-S 487
I W+ KG + + L R L +GSLLI D+G Y C +N G D + S
Sbjct: 720 TIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKS 779
Query: 488 ADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTE------ 541
L V IT P +G + M C + + +R WEK+ + E
Sbjct: 780 MYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVR--WEKEDRIINPEMARYLV 837
Query: 542 SHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLS 601
S + + +L I T D G ++C I++ G D L V++ P PE +
Sbjct: 838 STKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE---IEIK 894
Query: 602 TVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVD--PKATSVTVKGLVPAR 659
V+ R I L WT FDGNSP+ Y +E + W + D P+ S T+ + P+
Sbjct: 895 DVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSS 954
Query: 660 SYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
+Y R+ A N +GK + S + ++ E P PPQ V ++QSI + W+ P + Q
Sbjct: 955 TYSIRMYAKNRIGKSEPSNELT-ITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQ 1013
Query: 720 NGILKGYIIRYCLAGLPVGYQFKNI---TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG 776
NGI++GY I Y +QF I T D L++L +T Y + V A N AG G
Sbjct: 1014 NGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTG 1073
Query: 777 VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQ 836
S ++ TL+ VP+ PP NV A AT+ +I +W+ S + +NGI QG+++I W
Sbjct: 1074 PSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLM 1133
Query: 837 EEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG 896
+ E+ + Q S+ + GL+K+T Y VL FT GDG RS RT EDVPG
Sbjct: 1134 DGELGEIKNITTTQPSLE---LDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG 1190
Query: 897 PVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVT 956
P + + + + VSW P + NGI+ Y + T P+ + YR+
Sbjct: 1191 PPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPD-SFSYRIP 1249
Query: 957 GLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPG 1016
L+ Y++ V A+TS G+G S+ I+ V P P L S
Sbjct: 1250 NLSRNRQYSVWVVAVTSAGRGN-SSEIIT--VEPLAKAPARILTFSG------------- 1293
Query: 1017 YDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPD--LNPFTCYSFRMRQV 1074
T + W+ + + G+ + + + S+ D + F+ SF +R V
Sbjct: 1294 ----TVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV 1349
Query: 1075 N---------IVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY 1125
I + S +Q PPD VS T+S S+ L W+P
Sbjct: 1350 KAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSS--SITLSWLP----GD 1403
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGP 1185
NG GY ++Y S+ + + ER Y +E+L+ T Y+ + A N +G G
Sbjct: 1404 NGGSSIRGYILQY--SEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGR 1461
Query: 1186 WSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD 1245
S+ + +T P + L + ++ VR + + D + + + Y+ +
Sbjct: 1462 ISEIIEAKTLGKEPQF--SKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTT 1519
Query: 1246 TQPRFWLVEGNSSRSAQLTGLGK-YVLYEVQ 1275
W +AQ T L K Y+LY++Q
Sbjct: 1520 V----W-------TTAQRTSLSKSYILYDLQ 1539
Score = 195 bits (496), Expect = 4e-49
Identities = 184/697 (26%), Positives = 299/697 (42%), Gaps = 73/697 (10%)
Query: 930 ISWEEYNRT-NTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISS-- 986
+ WE+ +R N + YL + + G ++T +++ + G S I+S
Sbjct: 819 VRWEKEDRIINPEMARYLVST----KEVGEEVIST--LQILPTVREDSGFFSCHAINSYG 872
Query: 987 ------GVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEE 1040
+ + P P + I ++ R++TL++ G+DG + I+ + +E + + +
Sbjct: 873 EDRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECK----NKSDS 928
Query: 1041 WLLIHQLSN-EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
W + + P S + D++P + YS RM N +G S PS I +A PD
Sbjct: 929 WDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSN-ELTITADEAAPDGP 987
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD 1159
P V L S S+ + W + NG GY+I Y G +++ D
Sbjct: 988 PQEVHLEPISSQSIRVTWKAPKKHLQNGIIR--GYQIGYREYSTGGNFQFNIISVDTSGD 1045
Query: 1160 ---YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSM 1216
YT+++L ++T+Y + VQA N G+GP SQ ++ T E VPS P NV A+AT+ S+
Sbjct: 1046 SEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESI 1105
Query: 1217 LVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQV 1276
+ WS + + NG++ G++V+Y D + + S +L GL KY Y +QV
Sbjct: 1106 SISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQV 1165
Query: 1277 LAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQI 1336
LAFTR GDG S I RT +DVPGPP G+ + V + W PP NGII Y +
Sbjct: 1166 LAFTRAGDGVRSE-QIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTV 1224
Query: 1337 --THRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTT 1394
+H T + +P + Y L Y + A T G G ++E + V
Sbjct: 1225 FCSHPYPTVISEFEA----SPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITV-- 1278
Query: 1395 EKRDRPQPPSRPMVQQEDVRA---RSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHS 1451
+ P+R + V + ++L + D SP + + PS
Sbjct: 1279 --EPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDP-SPAVKWMKDSNGTPSLVTIDGR 1335
Query: 1452 ASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVT 1511
S+ N SFI+ +K S + A N+ G E + +Q PD+ L+V+
Sbjct: 1336 RSIFSN-GSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQ----VQVPPDQPR--LTVS 1388
Query: 1512 PHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMY 1571
T++S+ + W P D + G+ ++Y E E F +
Sbjct: 1389 KTTSSSITLSWLP--GDNGGSSIRGYILQYSEDNSEQWGSFPI----------------- 1429
Query: 1572 SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG 1608
PS Y L+NL Y+ ++ N VG G
Sbjct: 1430 ------SPSERSYRLENLKCGTWYKFTLTAQNGVGPG 1460
Score = 176 bits (445), Expect = 3e-43
Identities = 110/359 (30%), Positives = 174/359 (48%), Gaps = 22/359 (6%)
Query: 1401 QPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRW--ALHSASVSHNA 1458
+PP P ++ +DV+AR++ L W G DG SP+ Y I+ + S W A + VS
Sbjct: 884 EPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKN-KSDSWDSAQRTKDVSPQL 942
Query: 1459 SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSV 1518
+S + + P ++Y R+ A N IG SE S E ++T +AAPD P + + P ++ S+
Sbjct: 943 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNEL-TITADEAAPDGPPQEVHLEPISSQSI 1001
Query: 1519 LIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSR 1578
+ W+ P + NGI+ G++I YRE G F + ++ G +
Sbjct: 1002 RVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEV------------- 1048
Query: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT 1638
Y LDNLNK +Y + + N G GPSS E VP+ P NV +
Sbjct: 1049 -----YTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPE 1103
Query: 1639 QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMV 1698
+ ++W ++ NG +QG+++ +W +K + + S++L L YT Y +
Sbjct: 1104 SISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSI 1163
Query: 1699 SVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGY 1757
V AF AGDG RS +T++ P P+ VK + + + V VSW P NGI+ Y
Sbjct: 1164 QVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKY 1222
Score = 160 bits (405), Expect = 1e-38
Identities = 318/1528 (20%), Positives = 561/1528 (36%), Gaps = 161/1528 (10%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTH 85
PY T V Q + GN V C+ S + ++ R++ITS +
Sbjct: 125 PY--TVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALY 182
Query: 86 AGF---------YRCIVRNRMGALLQRQTEVQVAYMG------SFEEGEKHQSVSHGEAA 130
YRCI R+R ++ ++ S +G H+ G+
Sbjct: 183 IKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRV 242
Query: 131 VIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKN 190
+ + P+P W +D + S R T+ T +++ + P YV V+++
Sbjct: 243 ELPCKALGH-PEPDYRWLKDNMPLELSGRFQKTV--TGLLIENIRPSDSGSYVCEVSNRY 299
Query: 191 GDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHII 250
G K + + P+ TI P K S V S+V+L C +L
Sbjct: 300 GTAKVIGRLYVK--------QPLKATIS-PRKVKSSVG--SQVSLSCSVTGTEDQELS-- 346
Query: 251 WKKDGVLLSGG-----ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVL 305
W ++G +L+ G ++ L + + SD G Y+C VR LS
Sbjct: 347 WYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQC-----------FVRKDKLSAQ 395
Query: 306 EPPQFVKEP--ERHITAEMEKVVD------IPCQAKGVPPPSITWYKDAAVVEVEKLTRF 357
+ Q V E + I+A EKVV + C KG P P+ITW D + R
Sbjct: 396 DYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 455
Query: 358 RQR--NDGG----LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS 411
Q ++G L IS D G+++C A N+AG V + V P R +
Sbjct: 456 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG--PASIRPMKNI 513
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHIS-DA 470
T I G + C G P +I W K +L Q+ +G+L +S D
Sbjct: 514 TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFEN---NGTLKLSDVQKEVDE 570
Query: 471 GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYI 530
G YTC + + + V +P + G + + C V + I
Sbjct: 571 GEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGD-LPITIT 629
Query: 531 WEKDGATL-GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W+KDG + G+ +D SL IS G YTC + + L VR
Sbjct: 630 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKAT- 648
P P + +A+ L + P+ + + S+ +++ +
Sbjct: 690 PKFVVQP-RDQDGIYGKAVILNCSAE---GYPVPTIVWKFSKGAGVPQFQPIALNGRIQV 745
Query: 649 ----SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTN 704
S+ +K +V S + NDVG V +P + P + G+
Sbjct: 746 LSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKK 805
Query: 705 QS---------IMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLE 755
+ I+++W+ ++ I+ + RY ++ VG + I+ + + E
Sbjct: 806 EMSCTAHGEKPIIVRWEK-----EDRIINPEMARYLVSTKEVGEEV--ISTLQILPTVRE 858
Query: 756 DLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAP 815
D ++ + I NS G + + T+Q P P + + T+R+T
Sbjct: 859 DSGFFSCHAI-----NSYG---EDRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFD 910
Query: 816 SPQFING--INQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLC 873
I G I K +W+ Q + + ++ + + + Y +
Sbjct: 911 GNSPITGYDIECKNKSDSWDSAQRTK--------DVSPQLNSATIIDIHPSSTYSIRMYA 962
Query: 874 FTTPGDGPRSTPQLVRTHEDVP-GPVGHLSFSEILDTSLKVSWQEPGE--KNGILTGYRI 930
G S + E P GP + I S++V+W+ P + +NGI+ GY+I
Sbjct: 963 KNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQI 1022
Query: 931 SWEEYNRTNTRVTHYLPNVTLE-----YRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
+ EY+ T + +V Y + L T Y + V A G G S I+
Sbjct: 1023 GYREYS-TGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIIT 1081
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLI 1044
+ + PP N+ P S+++ + + I + + +GE +
Sbjct: 1082 TTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIK 1141
Query: 1045 HQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQTLQAPPDMAPAN 1102
+ + +P S+E+ L +T YS ++ G S+ +R + + PP A
Sbjct: 1142 NITTTQP---SLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPP----AG 1194
Query: 1103 VSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTI 1162
V AS + +++ W LP ++ NG + K S + +S Y I
Sbjct: 1195 VKAAAASASMVFVSW--LPPLKLNG----IIRKYTVFCSHPYPTVISEFEASPDSFSYRI 1248
Query: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222
+L +Y V V A + G G S+ + P+ + T S ++ W +
Sbjct: 1249 PNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPAR-------ILTFSGTVTTPWMK 1301
Query: 1223 VPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA---F 1279
+ + KDS+ P ++G S + G +++ V+ +
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRS----IFSNGSFIIRTVKAEDSGYY 1357
Query: 1280 TRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR 1339
+ I + + I+ VP + + ++S+ L W P I Y + +
Sbjct: 1358 SCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1417
Query: 1340 LNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEKRD 1398
+ + + ++PS R Y LK + Y F +TAQ G G +E + T K
Sbjct: 1418 EDNSEQWGSFP--ISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEP 1475
Query: 1399 RPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNA 1458
+ R R L+ W +DG P+ +T++ R P G +A + +
Sbjct: 1476 QFSKEQELFASINTTRVRLNLIGW---NDGGCPITSFTLEYR--PFGTTVWTTAQRTSLS 1530
Query: 1459 SSFIVDRLKPFTSYKFRVKATNDIGDSE 1486
S+I+ L+ T Y+ +++ N G +E
Sbjct: 1531 KSYILYDLQEATWYELQMRVCNSAGCAE 1558
Score = 137 bits (344), Expect = 1e-31
Identities = 163/659 (24%), Positives = 270/659 (40%), Gaps = 76/659 (11%)
Query: 1292 ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTAT-V 1350
I++ T+ + P PP I +V+ ++ L W N I Y I + + + ++A
Sbjct: 877 IIQLTVQEPPDPPE-IEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRT 935
Query: 1351 EVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQ 1410
+ ++P T + P S Y R+ A+ R G E + L +T ++ PP V
Sbjct: 936 KDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQE--VHL 993
Query: 1411 EDVRARSVLLSWEPGSDGLSP--VRYYTIQTRELPSG---RWALHSASVSHNASSFIVDR 1465
E + ++S+ ++W+ L +R Y I RE +G ++ + S S ++ + +D
Sbjct: 994 EPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDN 1053
Query: 1466 LKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPP 1525
L FT Y V+A N G S+E + TTL+ P P + + S+ I W
Sbjct: 1054 LNKFTQYGLVVQACNRAGTGPSSQEIIT-TTLEDVPSYPPENVQAIATSPESISISWSTL 1112
Query: 1526 AEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLS--RPSLTQ 1583
+++ +NGIL GFR+ Y L +G G ++N++ +PSL
Sbjct: 1113 SKEALNGILQGFRVIYWANLMDGELG--------------------EIKNITTTQPSL-- 1150
Query: 1584 YELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVT 1643
ELD L K+ Y I++ + G+G S E VP P V A+A+ + V+
Sbjct: 1151 -ELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVP-GPPAGVKAAAASASMVFVS 1208
Query: 1644 WEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAEN---SVKLKNLTGYTAYMVSV 1700
W PP NG I+ Y ++ ++E F A S ++ NL+ Y V V
Sbjct: 1209 WLPPL--KLNGIIRKYTVFCSHPYPTVISE-----FEASPDSFSYRIPNLSRNRQYSVWV 1261
Query: 1701 AAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLV 1760
A +AG G S + AP+ + FS TT + I+ + V
Sbjct: 1262 VAVTSAGRGNSSEIITVEPLAKAPAR--ILTFSGTVTTP---------WMKDIVLPCKAV 1310
Query: 1761 YEPCSPV------DGVSKIVTVD----VKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
+P V +G +VT+D + N ++ AE Y + A
Sbjct: 1311 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVK-AEDSGY-YSCIANNNWGSD 1368
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWD 1870
EI N+ + P P + + SS+I + W GD G I Y+++ + W
Sbjct: 1369 EIILNLQV---QVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWG 1425
Query: 1871 ILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEE 1929
P S ++ ++ LK G Y F + A N G G S ++ K F +E
Sbjct: 1426 ----SFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKE 1480
Score = 134 bits (337), Expect = 1e-30
Identities = 155/614 (25%), Positives = 238/614 (38%), Gaps = 46/614 (7%)
Query: 6 IWTL-LALHQIRAARAQDDV--SPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKW-- 60
+W L L+L Q A +D+ S YF ++ V ++ C A G P+ +W
Sbjct: 1 MWILALSLFQSFANVFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYL 60
Query: 61 --------------LHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTE 106
+H N L F T + H Y C N G + +
Sbjct: 61 ATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLI---HDNTYYCTAENPSGKIRSQDVH 117
Query: 107 VQVAYMGSFEEGEKHQSVSHGEAAVIRA--PRIASFPQPQVTWFRDGRKIPPSSRIAITL 164
++ + + Q G AV + P V+W +D + SR IT
Sbjct: 118 IKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITS 177
Query: 165 ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
L I V + G Y + + +T Q + + V PA+ AP+I+ +
Sbjct: 178 TGALYI-KDVQNEDGLYNYRCITRHRYTGETRQSNSARLF-VSDPANS-APSILDGFDHR 234
Query: 225 SVVAGTSEVTLECVANARPLIKLHIIWKKDGVLL--SGGISDHNRRLTIPNPTGSDAGYY 282
+AG V L C A P + W KD + L SG L I N SD+G Y
Sbjct: 235 KAMAG-QRVELPCKALGHP--EPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSY 291
Query: 283 ECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW 342
CE R + + R L V +P + P R + + + V + C G ++W
Sbjct: 292 VCEVSNRYGTAKVIGR---LYVKQPLKATISP-RKVKSSVGSQVSLSCSVTGTEDQELSW 347
Query: 343 YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAP 402
Y++ ++ K R N L + +V D G +QCF R Q + + P
Sbjct: 348 YRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 407
Query: 403 NITRGPLDSTVIDGMSVVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLES---G 458
I + V V L C G P P ITW + IL GS ++ + E
Sbjct: 408 KIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVS 467
Query: 459 SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCG 518
L IS + + D G Y C A NS GV A + V I +P ++ + I G + C
Sbjct: 468 YLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI-RPMKNITAIAGRDTYIHCR 526
Query: 519 VTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSG-DIGTYTCRV-ISAGG 576
V P +I+ W K+ + L +H ++ + NG+L +S D G YTC V +
Sbjct: 527 VIGYPYYSIK--WYKN-SNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQL 583
Query: 577 NDSRSAHLRVRQLP 590
+ S+S H+ V+ P
Sbjct: 584 STSQSVHVTVKVPP 597
Score = 76.3 bits (186), Expect = 3e-13
Identities = 75/283 (26%), Positives = 124/283 (43%), Gaps = 18/283 (6%)
Query: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG 576
C DP ++++ + +G R + NGS I + D G Y+C + G
Sbjct: 1307 CKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWG 1366
Query: 577 NDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAP- 635
+D +L+V Q+P P+ P T+S +I L+W +G S + YIL+ SE+N+
Sbjct: 1367 SDEIILNLQV-QVP--PDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQ 1423
Query: 636 WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQ 695
W + P S ++ L Y+F L A N VG G+ S+ E +L +EP + Q
Sbjct: 1424 WGSF--PISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQ 1481
Query: 696 NVIASGRTN--QSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNITDADVNNL 752
+ AS T + +I W + G + + + Y G V + + + +
Sbjct: 1482 ELFASINTTRVRLNLIGW------NDGGCPITSFTLEYRPFGTTVWTTAQRTSLS--KSY 1533
Query: 753 LLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPP 795
+L DL T YE+++ NSAG + G T+PP
Sbjct: 1534 ILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDG-STIPP 1575
Score = 42.4 bits (98), Expect = 0.005
Identities = 54/221 (24%), Positives = 91/221 (41%), Gaps = 23/221 (10%)
Query: 1622 VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE---AQRGNLTERVKTL 1678
VP PR + V T++ + ++W P D+ I+GY + + E Q G+ +
Sbjct: 1378 VPPDQPR-LTVSKTTSSSITLSWLPG--DNGGSSIRGYILQYSEDNSEQWGSFP-----I 1429
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPS-APSSVKFSELTT 1737
+E S +L+NL T Y ++ A N G G S + +T P + F+ + T
Sbjct: 1430 SPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINT 1489
Query: 1738 TSVN---VSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
T V + W P + + L Y P G + T S ++ + DL E
Sbjct: 1490 TRVRLNLIGWNDGGCP---ITSFTLEYRPF----GTTVWTTAQRTSLSKSYI-LYDLQEA 1541
Query: 1795 VTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
Y ++R E +AN T +G+ PP + +V+
Sbjct: 1542 TWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQ 1582
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 323 bits (828), Expect = 1e-87
Identities = 337/1312 (25%), Positives = 546/1312 (41%), Gaps = 145/1312 (11%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNR-ELTKFSLEYR------YMITSLDRTHAGFYRCIV 93
G+ ++L+C GS +W N L ++ R +ITS ++H+G Y+C
Sbjct: 389 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF- 447
Query: 94 RNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASF------PQPQVTW 147
A + QT A + + E+G S E V + + P P VTW
Sbjct: 448 -----ATRKAQTAQDFAII-ALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTW 501
Query: 148 FRDGRKIPP-----SSRIAITLENTLVILSTVAP---DAGRYYVQAVNDKNGDNKTSQPI 199
D I +++ ++ T+ ++ P D G Y A N ++
Sbjct: 502 ALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARI- 560
Query: 200 TLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
NV GP I +N + VAG + + C P + W KD +LL
Sbjct: 561 -----NVRGPPS------IRAMRNITAVAGR-DTLINCRVIGYPYYSIK--WYKDALLLP 606
Query: 260 GGISDHNRRLTIPNPT--------GSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFV 311
D++R++ N T G D G Y C +++ S+ + +++V PP
Sbjct: 607 ----DNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQL--SISQSVHVAVKVPPLI- 659
Query: 312 KEPERHITAEMEKVVDIPCQ-AKGVPPPSITWYKDAAVV-EVEKLTRFRQRNDGGLQISG 369
+P A + +++ IPC + G P ITW KD V+ +T + LQIS
Sbjct: 660 -QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISS 718
Query: 370 LVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAP 429
+ G + C A NAA V L V + P P + I G + VL C G P
Sbjct: 719 VSLKHNGNYTCIASNAAATVSRERQLIVR-VPPRFVVQPNNQDGIYGKAGVLNCSVDGYP 777
Query: 430 RPAITWQKGERILASGSVQLPRFTPLE-------SGSLLISPTHISDAGTYTCLATNSRG 482
P + W+ + SG+ Q PL + SLLI D G Y C A+N G
Sbjct: 778 PPKVMWKHAK---GSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 834
Query: 483 VD-EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTE 541
D S L V IT P IKG + C + + IR WEK + +
Sbjct: 835 TDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIR--WEKGDTVIDPD 892
Query: 542 SHPR--IRLDRNG-----SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE 594
R I NG +L + GD ++C I++ G D L V++ P PE
Sbjct: 893 RVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE 952
Query: 595 HPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLAS--VDPKATSVTV 652
+ V+ R++NL WT+ FDGNS + + +E + W ++ + P +
Sbjct: 953 ---LEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANI 1009
Query: 653 KGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQ 712
L PA Y R+ + N +G+ + SK+ +S E P PP +V T+QSI + W+
Sbjct: 1010 VDLHPASVYSIRMYSFNKIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWK 1068
Query: 713 PPPESHQNGILKGYIIRYCLAGLPVGYQFKNI---TDADVNNLLLEDLIIWTNYEIEVAA 769
P + QNG+++GY I Y Q+ + D L++L + Y + V A
Sbjct: 1069 APKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQA 1128
Query: 770 YNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKL 829
+N AG G SS++ TL+ VP+ PP NV A + S +W+ P +NG+ +GY++
Sbjct: 1129 FNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRV 1188
Query: 830 IAW----EPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTP 885
I W + E E + T R + + G++KFT Y VL +T GDG RS+
Sbjct: 1189 IFWSLYVDGEWGEMQNITTTRERVE-------LRGMEKFTNYSVQVLAYTQAGDGVRSSV 1241
Query: 886 QLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHY 945
++T EDVPGP + +S+ VSW P + NG++ Y I + Y
Sbjct: 1242 LYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEY 1301
Query: 946 LPN-VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNI 1004
+ L YR+ L Y + VAA+TS G+G S+ ++ + P + G +
Sbjct: 1302 ETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGN-SSEKVTIEPAGKAPAKIISFGGTVT 1360
Query: 1005 GP--RSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
P + V L D ++ +W +++ + + + + R+++ D
Sbjct: 1361 TPWMKDVRLPCNSVGDPAPAV-KWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSG 1419
Query: 1063 PFTCYS-----FRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRW 1117
+TC + F VN++ PP QP +++ S +S+ L W
Sbjct: 1420 YYTCTATNTGGFDTIIVNLLVQVPPDQP----------------RLTVSKTSASSITLTW 1463
Query: 1118 MPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQA 1177
+P NG G+ ++YS + + V ER + ++ L+ T Y+V++ A
Sbjct: 1464 IP----GDNGGSSIRGFVLQYSVD--NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAA 1517
Query: 1178 FNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKV 1237
N++GSG S+ + +T PS + L T +S R + + + +
Sbjct: 1518 KNSVGSGRISEIIEAKTHGREPSF--SKDQHLFTHINSTHARLNLQGWNNGGCPITAIVL 1575
Query: 1238 MYKEKDSDTQPRFWLVEG---NSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
Y+ K + W +G NSS LT L + YE+++ A G G+
Sbjct: 1576 EYRPKGT------WAWQGLRANSSGEVFLTELREATWYELRMRACNSAGCGN 1621
Score = 218 bits (555), Expect = 5e-56
Identities = 356/1569 (22%), Positives = 598/1569 (38%), Gaps = 169/1569 (10%)
Query: 1 MWGLLIWTLLALHQIRAARAQD-DVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFK 59
MW L+ LL L + AR +D S YF + ++ +V+ C A GS +
Sbjct: 61 MW--LVTFLLLLDSLHKARPEDVGTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALR 118
Query: 60 W----------------LHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQR 103
W +H N L + + + H Y C N G +
Sbjct: 119 WYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFI---HDNDYFCTAENAAGKIRSP 175
Query: 104 QTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQ--PQVTWFRDGRKIPPSSRIA 161
V+ + + + Q G AV + +S + V+W +D I P R
Sbjct: 176 NIRVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFF 235
Query: 162 ITLENTLVILSTVAPDAGRYYVQAVNDK-NGDNKTSQPITLTVENVGGPADPIAPTIIIP 220
IT L I DA Y K +G+ + S L+V + PA+ I PTI+
Sbjct: 236 ITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTD---PAESI-PTILDG 291
Query: 221 PKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNR--RLTIPNPTGSD 278
+ V AG + V L C A+ P+ + W KDG L R LTI + D
Sbjct: 292 FHSQEVWAGHT-VELPCTASGYPIPAIR--WLKDGRPLPADSRWTKRITGLTISDLRTED 348
Query: 279 AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPP 338
+G Y CE +++ S L V++P P++ T V+ + C G P
Sbjct: 349 SGTYICEV---TNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVI-LSCALTGSPEF 404
Query: 339 SITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT 398
+I WY++ +V ++ R ++ L I+ +G +QCFA A Q +A+
Sbjct: 405 TIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALE 464
Query: 399 SIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLES 457
P I + V G L C GAP P +TW E I+ GS + ++T +
Sbjct: 465 DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYT-MSD 523
Query: 458 GSLL----ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQA 513
G+ + ++ I D G Y C A N G E A + V I + ++ + + G
Sbjct: 524 GTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSI-RAMRNITAVAGRDT 582
Query: 514 SMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSG-DIGTYTCRV- 571
+ C V P +I+ W KD A L ++H ++ + NG+L ++ G D G Y C V
Sbjct: 583 LINCRVIGYPYYSIK--WYKD-ALLLPDNHRQVVFE-NGTLKLTDVQKGMDEGEYLCSVL 638
Query: 572 ISAGGNDSRSAHLRVRQLP--HAPEHPVATLSTV---------ERRAINLTWTKPFDGNS 620
I + S+S H+ V+ P E P A++ + I +TW K DG
Sbjct: 639 IQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRK--DG-- 694
Query: 621 PLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT 680
+ I+ S ++S+ + S+ G + A N +
Sbjct: 695 ---QVIISGSGVTIESKEFMSSLQISSVSLKHNG-------NYTCIASNAAA----TVSR 740
Query: 681 ERVSLPEEPP--TAPPQNVIA----SGRTNQSIMIQWQPPPE---SHQNGILKGYIIRYC 731
ER + PP P N +G N S + PPP+ H G G +Y
Sbjct: 741 ERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCS--VDGYPPPKVMWKHAKG--SGNPQQYH 796
Query: 732 LAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVP 791
L Q + + ++L ED+ + A N G + S + +
Sbjct: 797 PVPLTGRIQILPNSSLLIRHVLEEDIGYYL-----CQASNGVGTDISKSMFLTVKIPAMI 851
Query: 792 TVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851
T P A ++ + T P I +G +I +P++ + T + N +
Sbjct: 852 TSHPNTTIAIKGHAKELNCTARGERPIIIRW-EKGDTVI--DPDRVMRYAIAT-KDNGDE 907
Query: 852 SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
+ + + F S + G+ V+ D P L E+ S+
Sbjct: 908 VVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPP----ELEIREVKARSM 963
Query: 912 KVSWQEPGEKNGILTGYRISWEEYNRTNT----RVTHYLPNVTLEYRVTGLTALTTYTIE 967
+ W + + N I+TG+ I ++ N++++ + T + + + L + Y+I
Sbjct: 964 NLRWTQRFDGNSIITGFDIEYK--NKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIR 1021
Query: 968 VAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISR- 1025
+ + G+ + S S GPP ++ + + +S+ + ++ P + + + R
Sbjct: 1022 MYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRG 1081
Query: 1026 WLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 1085
+ + + G ++ ++ ++ D+ + +L F Y ++ N GT PS
Sbjct: 1082 YQIGYRENSPGSNGQYSIV-EMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSS 1139
Query: 1086 SRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY--SRSDG 1143
TL+ P P NV + + + W P NG + GY++ + DG
Sbjct: 1140 EINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLK--GYRVIFWSLYVDG 1197
Query: 1144 HGKTLSHV--VQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSS 1201
+ ++ ++RVE + +E++T Y VQV A+ G G S + +T+E VP
Sbjct: 1198 EWGEMQNITTTRERVE----LRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGP 1253
Query: 1202 GPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA 1261
P + A+ +++SS++V W +P NG++ Y + S
Sbjct: 1254 -PAGIKAVPSSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFY 1310
Query: 1262 QLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT----SV 1317
++ L + Y + V A T G G+ S +E P I F TT V
Sbjct: 1311 RIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPA---GKAPAKIISFGGTVTTPWMKDV 1367
Query: 1318 RL----IWQPPAA-------PNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLK 1366
RL + P A + I HRL T V A + YT
Sbjct: 1368 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTC---- 1423
Query: 1367 PESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS 1426
TA G+ L+V PP +P + A S+ L+W PG
Sbjct: 1424 ---------TATNTGGFDTIIVNLLVQV-------PPDQPRLTVSKTSASSITLTWIPGD 1467
Query: 1427 DGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSE 1486
+G S +R + +Q S W +S + SF +D LK T YK ++ A N +G
Sbjct: 1468 NGGSSIRGFVLQYSVDNSEEW--KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1525
Query: 1487 FSEESESLT 1495
SE E+ T
Sbjct: 1526 ISEIIEAKT 1534
Score = 184 bits (468), Expect = 6e-46
Identities = 186/739 (25%), Positives = 315/739 (42%), Gaps = 87/739 (11%)
Query: 993 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN-EP 1051
P P L I + RS+ L++ +DG + I+ + +E + + + W N P
Sbjct: 947 PPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYK----NKSDSWDFKQSTRNISP 1002
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1111
+ DL+P + YS RM N +G S PS+ I T +A PD P +V+L+ +
Sbjct: 1003 TINQANIVDLHPASVYSIRMYSFNKIGRSEPSK-ELTISTEEAAPDGPPMDVTLQPVTSQ 1061
Query: 1112 SLWLRWM-PLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD---YTIEDLEE 1167
S+ + W P E++ N GY+I Y + +V+ + D YT+++L++
Sbjct: 1062 SIQVTWKAPKKELQ---NGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKK 1118
Query: 1168 WTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
+ +Y V VQAFN G+GP S + T E VPS P NV AL+ TS ++ WSE P +
Sbjct: 1119 FAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRST 1178
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
NG++ GY+V++ D + + +L G+ K+ Y VQVLA+T+ GDG
Sbjct: 1179 LNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVR 1238
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANT 1347
S ++ T +DVPGPP GI +SV + W PP PNG+I Y I +
Sbjct: 1239 SSVLYIQ-TKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPA 1297
Query: 1348 ATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQ------ 1401
+ +P Y L YL + A T G G ++E + + + +
Sbjct: 1298 PSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGG 1357
Query: 1402 PPSRPMVQQEDVRARSV-----LLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVS 1455
+ P ++ + SV + W S D PV ++ +
Sbjct: 1358 TVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPV---------------SMDGHRLI 1402
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTT 1515
H + ++ +K S + ATN G ++ + L P + P L+V+ +
Sbjct: 1403 HTNGTLLLRAVKAEDSGYYTCTATNTGG-----FDTIIVNLLVQVPPDQPR-LTVSKTSA 1456
Query: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
+S+ + W P NG +RGF L+ + W ++ S R+
Sbjct: 1457 SSITLTWIPGD----NG-------------GSSIRGFVLQYSVDNSEEWKDVFISSSERS 1499
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT-AAPRNVVVH- 1633
++LD+L Y+++++ N+VG G S E P+ + +++ H
Sbjct: 1500 --------FKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHI 1551
Query: 1634 GATATQLDVT-WEPP--PLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNL 1690
+T +L++ W P+ + + + + W+ R N + V L L
Sbjct: 1552 NSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRAN----------SSGEVFLTEL 1601
Query: 1691 TGYTAYMVSVAAFNAAGDG 1709
T Y + + A N+AG G
Sbjct: 1602 REATWYELRMRACNSAGCG 1620
Score = 177 bits (449), Expect = 1e-43
Identities = 126/461 (27%), Positives = 207/461 (44%), Gaps = 41/461 (8%)
Query: 1401 QPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSAS--VSHNA 1458
+PP P ++ +V+ARS+ L W DG S + + I+ + S W ++ +S
Sbjct: 946 EPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKN-KSDSWDFKQSTRNISPTI 1004
Query: 1459 SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSV 1518
+ + L P + Y R+ + N IG SE S+E +++T +AAPD P +++ P T+ S+
Sbjct: 1005 NQANIVDLHPASVYSIRMYSFNKIGRSEPSKEL-TISTEEAAPDGPPMDVTLQPVTSQSI 1063
Query: 1519 LIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSR 1578
+ W+ P ++ NG++ G++I YRE N+PG+ YS+ +
Sbjct: 1064 QVTWKAPKKELQNGVIRGYQIGYRE--------------NSPGSN-----GQYSIVEMKA 1104
Query: 1579 PSLTQ-YELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATA 1637
++ Y LDNL K +Y + + +N G GPSS E VP+ P NV T+
Sbjct: 1105 TGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITS 1164
Query: 1638 TQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYM 1697
++W PP + NG ++GY++ FW ++ + V+L+ + +T Y
Sbjct: 1165 DVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYS 1224
Query: 1698 VSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGY 1757
V V A+ AGDG RS+ QT++ P P+ +K + +SV VSW P PNG++ Y
Sbjct: 1225 VQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKY 1284
Query: 1758 RLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVT 1817
+ CS + L+ ++ L G Y + A T VT
Sbjct: 1285 TIF---CSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVT 1341
Query: 1818 TGPGEGAPGPPGVPIIVRYSSAIAIHW---------SSGDP 1849
P AP I+ + + W S GDP
Sbjct: 1342 IEPAGKAPAK-----IISFGGTVTTPWMKDVRLPCNSVGDP 1377
Score = 133 bits (335), Expect = 2e-30
Identities = 148/631 (23%), Positives = 259/631 (41%), Gaps = 58/631 (9%)
Query: 1292 ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN-TATV 1350
+++ T+ + P PP + EV+ S+ L W N II + I ++ + + + +
Sbjct: 939 LIQLTVQEPPDPPE-LEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQST 997
Query: 1351 EVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQ 1410
++P+ Q L P SVY R+ + + G E ++ L ++TE+ PP V
Sbjct: 998 RNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMD--VTL 1055
Query: 1411 EDVRARSVLLSWEPGSDGL--SPVRYYTIQTREL---PSGRWALHSASVSHNASSFIVDR 1465
+ V ++S+ ++W+ L +R Y I RE +G++++ + ++ + +D
Sbjct: 1056 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1115
Query: 1466 LKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPP 1525
LK F Y V+A N G S E + TTL+ P + P + T+ +I W P
Sbjct: 1116 LKKFAQYGVVVQAFNRAGTGPSSSEINA-TTLEDVPSQPPENVRALSITSDVAVISWSEP 1174
Query: 1526 AEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYE 1585
+NG+L G+R+ + L +G W E+ ++ + R + E
Sbjct: 1175 PRSTLNGVLKGYRVIFWSLYVDG--------------EWGEMQNITTTRE-------RVE 1213
Query: 1586 LDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWE 1645
L + K Y +++ Y G+G S + E VP P + ++A+ + V+W
Sbjct: 1214 LRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWL 1272
Query: 1646 PPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNA 1705
PP NG I+ Y I+ G + ++ +L Y++ VAA +
Sbjct: 1273 PP--TKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTS 1330
Query: 1706 AGDGPRSTPTQGQTQQAAPSAPSS-VKFSELTTT----SVNVSWEAPQFPNGILEGYRLV 1760
AG R ++ T + A AP+ + F TT V + + P ++ +
Sbjct: 1331 AG---RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDS 1387
Query: 1761 YEPCSPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTT 1818
+ PV DG I T N L L+ AE Y T + I +
Sbjct: 1388 EDSAIPVSMDGHRLIHT-----NGTLLLRAVK-AEDSGYYTCTATNTGGFDTIIVNLLVQ 1441
Query: 1819 GPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPK 1878
P P P + + +S+I + W GD G I +V++ + W KD+
Sbjct: 1442 VP----PDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEW----KDVFI 1493
Query: 1879 EVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
S +F +D LK G Y ++ A N G G
Sbjct: 1494 SSSERSFKLDSLKCGTWYKVKLAAKNSVGSG 1524
Score = 122 bits (307), Expect = 3e-27
Identities = 135/523 (25%), Positives = 213/523 (40%), Gaps = 65/523 (12%)
Query: 1416 RSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFT---SY 1472
R +++ WE G + P R R+A+ + S + +LKP S
Sbjct: 876 RPIIIRWEKGDTVIDPDRVM----------RYAIATKDNGDEVVSTL--KLKPADRGDSV 923
Query: 1473 KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKING 1532
F A N G+ + T+Q PD P L + S+ +RW + N
Sbjct: 924 FFSCHAINSYGE----DRGLIQLTVQEPPD--PPELEIREVKARSMNLRWTQRFDG--NS 975
Query: 1533 ILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKH 1592
I+ GF I Y+ N +W S RN+S P++ Q + +L+
Sbjct: 976 IITGFDIEYK----------------NKSDSW---DFKQSTRNIS-PTINQANIVDLHPA 1015
Query: 1593 RRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQ 1652
Y IRM +N +G S + EA P P +V + T+ + VTW+ P + Q
Sbjct: 1016 SVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQ 1075
Query: 1653 NGDIQGYKIYFWEAQRGNLTER--VKTLFLAENSV-KLKNLTGYTAYMVSVAAFNAAGDG 1709
NG I+GY+I + E G+ + V+ ++ V L NL + Y V V AFN AG G
Sbjct: 1076 NGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTG 1135
Query: 1710 PRSTPTQGQTQQAAPSAP-SSVKFSELTTTSVNVSWEAPQFP--NGILEGYRLVYEPCSP 1766
P S+ T + PS P +V+ +T+ +SW P NG+L+GYR+++
Sbjct: 1136 PSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLY- 1194
Query: 1767 VDG----VSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVT-TGPG 1821
VDG + I T + ++++ + + Y ++ A T G + ++V
Sbjct: 1195 VDGEWGEMQNITTTRER------VELRGMEKFTNYSVQVLAYTQA-GDGVRSSVLYIQTK 1247
Query: 1822 EGAPGPP-GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEV 1880
E PGPP G+ + +S++ + W G I +Y I S G +
Sbjct: 1248 EDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFC--SSPGSGQPAPSEYETSP 1305
Query: 1881 SSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKA 1923
+ + L G Y V AV G G S PA KA
Sbjct: 1306 EQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKA 1348
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 311 bits (796), Expect = 6e-84
Identities = 272/1020 (26%), Positives = 452/1020 (44%), Gaps = 80/1020 (7%)
Query: 5 LIWTLLALHQIRAARAQDDV--SPYFKTEP--VRTQVHLEGNRLVLTCMAEGSWPLEFKW 60
L+W L+ L + + A D + P F EP V + L + ++L C A G ++W
Sbjct: 3 LLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRW 62
Query: 61 LHNNRELTKFSLEYRYMIT----SLDRTHA----GFYRCIVRNRMGALLQRQTEVQVAYM 112
N ++ F++ Y Y + +++ H G Y+C+ N +G +L R+ ++Q AY+
Sbjct: 63 KQNGTDID-FTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYI 121
Query: 113 GSFEEGEKHQ-SVSHGEAAVIRAPRIASFPQPQVTW-FRDGRK-IPPSSRIAITLENTLV 169
FE + SV G+ V+ F W F D + +R ++ E +
Sbjct: 122 EDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNL 181
Query: 170 ILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAG 229
++ V P Y + +K P T V+ G P I + T A
Sbjct: 182 YIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAK 241
Query: 230 TSEVTLECVANARPLIKLHIIWKK-DGVLLSGGI--SDHNRRLTIPNPTGSDAGYYECEA 286
S V LEC A P+ I W++ DG L G + S L IPN D G+YEC A
Sbjct: 242 DSSVKLECFALGNPVPD--ISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIA 299
Query: 287 V-LRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKD 345
LR ++ +G + P K H++ + + C+A G P P TW K+
Sbjct: 300 SNLRGRNL---AKGQLIFYAPPEWEQKIQNTHLSIYDNLLWE--CKASGKPNPWYTWLKN 354
Query: 346 AAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ E+ Q +G L I+ L D+G++QC A N + + L V + AP+ +
Sbjct: 355 GERLNPEERI---QIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFS 411
Query: 406 RGPLD--STVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLIS 463
+ P+ S V G +V+ C+ + PR AI+W++G L Q R LE GSL I
Sbjct: 412 KSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLR----QSKRIFLLEDGSLKIY 467
Query: 464 PTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP 523
SDAG+YTC+ATN G + + L+V RT IT PP V G + C V+HDP
Sbjct: 468 NITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDP 527
Query: 524 RVTIRYIWEKDGATL----GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDS 579
+ + ++W +G + G RI + G L I G Y C V + + S
Sbjct: 528 SIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLS 587
Query: 580 RSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVL 639
A + VR P PE + + L+W D NSP+ + + + P++V
Sbjct: 588 AVADIIVRGPPGPPED--VQVEDISSTTSQLSWRAGPDNNSPIQIFTI---QTRTPFSVG 642
Query: 640 LASV-------DPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 692
+V + K + TV GL P Y+FR+ A N +G G+ S+ +E + P
Sbjct: 643 WQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVV 702
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVG---YQFKNITDADV 749
P N+ G + ++I W+ PE QNG GYII + PVG + + ++ +
Sbjct: 703 APVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF----RPVGSTTWSKEKVSSVES 758
Query: 750 NNLLL--EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
+ + E +I + +E++V YN+ G G S+ ++ + P + P ++ +++
Sbjct: 759 SRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASE 818
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
+ +WNA + G GY+++ W + +E + + ++ ++GLK T Y
Sbjct: 819 MEVSWNAIAWNRNTGRVLGYEVLYWTDDSKES---MIGKIRVSGNVTTKNITGLKANTIY 875
Query: 868 FTSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQ--EPGEKNGI 924
F SV + T G GP S P V T + P P ++++ ++ ++ L ++W+ + E
Sbjct: 876 FASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAW-KLTNSKLCLNWEHVKTMENESE 934
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT----TYTIEVAAMTSKGQGQVS 980
+ GY+I + + ++ T + LE T L Y IE+ ++ G G S
Sbjct: 935 VLGYKILYRQNRQSKTHI--------LETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSS 986
Score = 146 bits (369), Expect = 2e-34
Identities = 110/376 (29%), Positives = 182/376 (48%), Gaps = 39/376 (10%)
Query: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVS 1455
R P PP VQ ED+ + + LSW G D SP++ +TIQTR S W A+ +
Sbjct: 595 RGPPGPPED--VQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEI 652
Query: 1456 HNASSF--IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH 1513
N ++ V L P+ Y+FRV A N IG E SE SE L T + P AP +
Sbjct: 653 LNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGG 712
Query: 1514 TTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE--LTSMY 1571
+ + ++I W+ E+ NG G+ I +R + TW++ ++S+
Sbjct: 713 SRSELVITWESIPEELQNGEGFGYIIMFRPV---------------GSTTWSKEKVSSVE 757
Query: 1572 SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVV 1631
S R + Y +++ +E+++ VYN GEG S V+ GE P APR
Sbjct: 758 SSRFV-------YRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTS 810
Query: 1632 VHGATATQLDVTWEPPPLDSQNGDIQGYKIYFW-EAQRGNLTERVKTLFLAENSVKLKNL 1690
+ +A++++V+W + G + GY++ +W + + ++ +++ +V KN+
Sbjct: 811 LQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIR----VSGNVTTKNI 866
Query: 1691 TGY---TAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAP 1747
TG T Y SV A+N AG GP S P T+++ PS P + +LT + + ++WE
Sbjct: 867 TGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHV 926
Query: 1748 QFPNGILE--GYRLVY 1761
+ E GY+++Y
Sbjct: 927 KTMENESEVLGYKILY 942
Score = 115 bits (287), Expect = 6e-25
Identities = 96/392 (24%), Positives = 165/392 (42%), Gaps = 17/392 (4%)
Query: 980 SASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGE 1039
S S ++ + PGPP ++ + +I + L +R G D + I + ++ + +
Sbjct: 585 SLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQ 644
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
+ ++ N + V L+P+ Y FR+ N +G PS+PS ++T + P +A
Sbjct: 645 AVATVPEILNGKTYNATVV-GLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVA 703
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY---SRSDGHGKTLSHVVQDRV 1156
P N+ S + L + W +PE NG E GY I + + + +S V R
Sbjct: 704 PVNIHGGGGSRSELVITWESIPEELQNG--EGFGYIIMFRPVGSTTWSKEKVSSVESSRF 761
Query: 1157 ERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSM 1216
Y E + + + V+V +N G G S + + E P P S + ++S M
Sbjct: 762 V--YRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEM 819
Query: 1217 LVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQV 1276
V W+ + G VLGY+V+Y DS + + + +TGL +Y V
Sbjct: 820 EVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASV 879
Query: 1277 LAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQ--PPAAPNGIILAY 1334
A+ G G PS PP+ T P P + ++ + + L W+ +L Y
Sbjct: 880 RAYNTAGTG-PSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGY 938
Query: 1335 QITHRLNTTT------ANTATVEVLAPSARQY 1360
+I +R N + N + E+L P Y
Sbjct: 939 KILYRQNRQSKTHILETNNTSAELLVPFEEDY 970
Score = 96.3 bits (238), Expect = 3e-19
Identities = 95/406 (23%), Positives = 172/406 (42%), Gaps = 25/406 (6%)
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
P P +V + S T+ L W P+ ++ + +S T+ ++ +
Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGK 656
Query: 1156 VERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSS 1214
+ T+ L W EY +V A N+IG G P + + RT+ SVP P N+ + S
Sbjct: 657 TY-NATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRS 715
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSS-RSAQLTGLGKYVL-- 1271
+++ W +PE +NG GY +M++ S T W E SS S++ + ++
Sbjct: 716 ELVITWESIPEELQNGEGFGYIIMFRPVGSTT----WSKEKVSSVESSRFVYRNESIIPL 771
Query: 1272 --YEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPA--AP 1327
+EV+V + G+GS S I+ D+ P G + + + W A
Sbjct: 772 SPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRN 831
Query: 1328 NGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA 1387
G +L Y++ + + + + ++ + TGLK ++Y + A G G ++
Sbjct: 832 TGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSS 891
Query: 1388 EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPSG 1445
+ VTT+K QPP+ + + + + L+WE + S V Y I R+
Sbjct: 892 PPVNVTTKKSPPSQPPANIAWKLTNSK---LCLNWEHVKTMENESEVLGYKILYRQNRQS 948
Query: 1446 RWALHSASVSHNASSFIVDRLKPF-TSYKFRVKATNDIGDSEFSEE 1490
+ H ++ ++ +V PF Y ++ +D GD SEE
Sbjct: 949 K--THILETNNTSAELLV----PFEEDYLIEIRTVSDGGDGSSSEE 988
Score = 61.6 bits (148), Expect = 8e-09
Identities = 70/293 (23%), Positives = 123/293 (41%), Gaps = 16/293 (5%)
Query: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPG-PPMGILFPEVRTTSVR 1318
+A + GL +V YE +V+A IG G PS P L RT VP P+ I + +
Sbjct: 659 NATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELV 718
Query: 1319 LIWQ--PPAAPNGIILAYQITHR-LNTTTANTATVEVLAPSARQYTATGLKPESVYLFRI 1375
+ W+ P NG Y I R + +TT + V + S Y + P S + ++
Sbjct: 719 ITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKV 778
Query: 1376 TAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSV---LLSWEPGSDGLS-- 1430
+G G + +V + + + P +Q V ++W + +
Sbjct: 779 GVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGY 838
Query: 1431 PVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
V Y+T ++E G+ VS N ++ + LK T Y V+A N G S
Sbjct: 839 EVLYWTDDSKESMIGK-----IRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGP-SSP 892
Query: 1491 SESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRE 1543
++TT ++ P + P ++ T + + + W+ + +LG++I YR+
Sbjct: 893 PVNVTTKKSPPSQPPANIA-WKLTNSKLCLNWEHVKTMENESEVLGYKILYRQ 944
Score = 53.9 bits (128), Expect = 2e-06
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 1826 GPPGVPIIVRY----SSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
GPPG P V+ S+ + W +G PI + I+ R W + +P+ ++
Sbjct: 596 GPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQA-VATVPEILN 654
Query: 1882 SYTFSMDI--LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
T++ + L P V Y+FRV+A N G G PS PS+ + + + P
Sbjct: 655 GKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVP 700
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 310 bits (794), Expect = 1e-83
Identities = 274/1010 (27%), Positives = 436/1010 (43%), Gaps = 62/1010 (6%)
Query: 5 LIWTLLALHQIRAARAQDDV--SPYFKTEP--VRTQVHLEGNRLVLTCMAEGSWPLEFKW 60
L W LL L A D P F EP V + E ++ L C +G+ +W
Sbjct: 3 LPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRW 62
Query: 61 LHNNRELTKFSLEYRY-------MITSLDRTH-AGFYRCIVRNRMGALLQRQTEVQVAYM 112
N ++ +++RY +I + ++T AG Y+C N G ++ R+ ++Q AY+
Sbjct: 63 KLNGTDVDT-GMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYL 121
Query: 113 GSFEEGEKHQ-SVSHGEAAVIRAPRIASFPQPQVTW-FRDGRKIPPSSRIAITLENTLVI 170
+F+ + SV G+ V+ + W F + + R L I
Sbjct: 122 DNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYI 181
Query: 171 LSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGT 230
D G Y N P L + N G + P I + T A
Sbjct: 182 AKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGE-YEPKIEVQFPETVPTAKG 240
Query: 231 SEVTLECVANARPLIKLHIIWKK-DGVLLSGGISDH--NRRLTIPNPTGSDAGYYECEAV 287
+ V LEC A P+ IIW++ DG ++ H N L IPN DAG YEC V
Sbjct: 241 ATVKLECFALGNPVPT--IIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYEC--V 296
Query: 288 LRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAA 347
+S +V RG +P K + H+ ME+ V C+A G P P+ W K+
Sbjct: 297 AENSRGKNVARGQLTFYAQPNWIQKINDIHVA--MEENVFWECKANGRPKPTYKWLKNGE 354
Query: 348 VVEVEKLTRFR-QRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITR 406
+ LTR R Q G L I+ + D GM+QC A N G + ++ L+V ++ P+ +R
Sbjct: 355 PL----LTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSR 410
Query: 407 GPLDSTVID--GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISP 464
L + G VV+ C+ +P+P TW+KG IL R T E G+L I
Sbjct: 411 TLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENE----RITISEDGNLRIIN 466
Query: 465 THISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPR 524
SDAG+YTC+ATN G ++ +LVV TR+ PP V G + C VTHD
Sbjct: 467 VTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHS 526
Query: 525 VTIRYIWEKDGATL-----GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDS 579
+ I + W +G + G D G L I G Y C V ++ S
Sbjct: 527 LDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLS 586
Query: 580 RSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE-MSENNAPW-- 636
+A L VR P PE T+ + L+W D +SP+ Y+++ + + W
Sbjct: 587 AAADLIVRGPPGPPE--AVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQA 644
Query: 637 -TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQ 695
+ + +D K + TV GL P Y+FR A N +G G+ S+ +E+ E P P
Sbjct: 645 VSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPA 704
Query: 696 NVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL- 754
NV G + ++I W+ PE QNG GY++ + G + + + AD + +
Sbjct: 705 NVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMI-WMLTVLASADASRYVFR 763
Query: 755 -EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWN 813
E + ++ +E++V +N+ G G +S ++ + PT PP ++ A + ++T I W
Sbjct: 764 NESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWA 823
Query: 814 APSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLC 873
+P + G QGY++ W E +EE Q S ++ LK Y +V
Sbjct: 824 SPLEK-NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTK---ITNLKGSVLYHLAVKA 879
Query: 874 FTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQEPG--EKNGILTGYRI 930
+ + G GP S V T + P P G++ ++ D+ + ++W + + + GY++
Sbjct: 880 YNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNWDQVKALDNESEVKGYKV 938
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS 980
+ +NR ++ ++E L Y IE+ + G G S
Sbjct: 939 LY-RWNRQSSTSVIETNKTSVE---LSLPFDEDYIIEIKPFSDGGDGSSS 984
Score = 141 bits (356), Expect = 6e-33
Identities = 106/381 (27%), Positives = 171/381 (44%), Gaps = 32/381 (8%)
Query: 1386 AAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSG 1445
AA L+V R P PP + +++ + LSW PG D SP+ Y IQ R S
Sbjct: 587 AAADLIV----RGPPGPPEAVTI--DEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSV 640
Query: 1446 RWALHSAS---VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
W S + + V L P+ Y+FR A N IG E S SE T +A P+
Sbjct: 641 GWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPE 700
Query: 1503 EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGA 1562
P +S + + ++I W+ E+ NG G+ + +R G + L + + A
Sbjct: 701 VTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPY---GKMIWMLTVLASADA 757
Query: 1563 TWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV 1622
S Y RN ++++ +E+++ V+N GEGP SP V+ E
Sbjct: 758 ------SRYVFRN-----------ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEE 800
Query: 1623 PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
PT P ++ +AT ++V W PL+ G IQGY++ +W + R +
Sbjct: 801 PTKPPASIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQ 859
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
S K+ NL G Y ++V A+N+AG GP S T++ PS P + + + +
Sbjct: 860 TSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIIL 919
Query: 1743 SWEAPQFPNGILE--GYRLVY 1761
+W+ + + E GY+++Y
Sbjct: 920 NWDQVKALDNESEVKGYKVLY 940
Score = 130 bits (326), Expect = 2e-29
Identities = 108/384 (28%), Positives = 179/384 (46%), Gaps = 28/384 (7%)
Query: 993 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV-VGEGEEWLLIHQLSNEP 1051
PGPP + I I + L +RPG D + I+ ++++A+ VG W + +
Sbjct: 597 PGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVG----WQAVSTVPELI 652
Query: 1052 DARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
D ++ V LNP+ Y FR N++G PS+PS K +T +A P++ PANVS S
Sbjct: 653 DGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGS 712
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVV----QDRVERDYTIEDL 1165
++ L + W +PE NG GY + + +GK + + D + E +
Sbjct: 713 KSELVITWETVPEELQNG--RGFGYVVAFR---PYGKMIWMLTVLASADASRYVFRNESV 767
Query: 1166 EEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPE 1225
++ + V+V FN G GP+S T V + E P+ P ++ A + +++ + V W+ E
Sbjct: 768 HPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLE 827
Query: 1226 ADRNGLVLGYKVMY-KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGD 1284
+R G + GY+V Y + +D + R GN + S ++T L VLY + V A+ G
Sbjct: 828 KNR-GRIQGYEVKYWRHEDKEENARKIRTVGNQT-STKITNLKGSVLYHLAVKAYNSAGT 885
Query: 1285 GSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIW-QPPAAPN-GIILAYQITHRLNT 1342
G PS + T P P G + + + L W Q A N + Y++ +R N
Sbjct: 886 G-PSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNR 944
Query: 1343 TTA------NTATVEVLAPSARQY 1360
++ N +VE+ P Y
Sbjct: 945 QSSTSVIETNKTSVELSLPFDEDY 968
Score = 101 bits (252), Expect = 7e-21
Identities = 98/404 (24%), Positives = 163/404 (40%), Gaps = 22/404 (5%)
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
P P V++ ++T+ L W P P+ N +P ++ Y I+ G V +
Sbjct: 596 PPGPPEAVTIDEITDTTAQLSWRPGPD---NHSPITM-YVIQARTPFSVGWQAVSTVPEL 651
Query: 1156 VERDY---TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALAT 1211
++ T+ L W EY + A N IG G P + RT E++P P NVS
Sbjct: 652 IDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGG 711
Query: 1212 TSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYV 1270
+ S +++ W VPE +NG GY V ++ L ++SR + + +
Sbjct: 712 SKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFS 771
Query: 1271 LYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPN-G 1329
+EV+V F G+G S ++ ++ PP I + T + + W P N G
Sbjct: 772 PFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRG 831
Query: 1330 IILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA 1389
I Y++ + + A + T LK +Y + A G G ++
Sbjct: 832 RIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSAT 891
Query: 1390 LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPSGRW 1447
+ VTT K QPP + D + ++L+W+ D S V+ Y + RW
Sbjct: 892 VNVTTRKPPPSQPPGNIIWNSSDSK---IILNWDQVKALDNESEVKGYKVLY------RW 942
Query: 1448 ALHSASVSHNASSFIVDRLKPF-TSYKFRVKATNDIGDSEFSEE 1490
S++ + V+ PF Y +K +D GD SE+
Sbjct: 943 NRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQ 986
Score = 63.2 bits (152), Expect = 3e-09
Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 1823 GAPGPPGVPIIVRYSSAIA-IHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
G PGPP I + A + W G PIT YVI+AR W + +P+ +
Sbjct: 595 GPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQA-VSTVPELID 653
Query: 1882 SYTFSMDI--LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
TF+ + L P V Y+FR +A N G G PS PS+ ++A P
Sbjct: 654 GKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALP 699
Score = 61.2 bits (147), Expect = 1e-08
Identities = 90/450 (20%), Positives = 168/450 (37%), Gaps = 39/450 (8%)
Query: 791 PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 850
P PP V + TT + +W P P + I Y + A P + T
Sbjct: 596 PPGPPEAVTIDEITDTTAQLSWR-PGPDNHSPITM-YVIQARTPFSVGWQAVSTVPELID 653
Query: 851 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTP-QLVRTHEDVPGPV-GHLSFSEILD 908
V GL + EY + G G S P + RT E +P ++S
Sbjct: 654 GKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSK 713
Query: 909 TSLKVSWQEPGEK--NGILTGYRISWEEYNRTNTRVTHYLPNVTLEY--RVTGLTALTTY 964
+ L ++W+ E+ NG GY +++ Y + +T Y R + + +
Sbjct: 714 SELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPF 773
Query: 965 TIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV------TLQFRPGYD 1018
++V +KG+G S +T+ E PP ++ ++ + L+ G
Sbjct: 774 EVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRI 833
Query: 1019 GKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG 1078
+ W E + E I + N+ S ++ +L Y ++ N G
Sbjct: 834 QGYEVKYWRHE------DKEENARKIRTVGNQ---TSTKITNLKGSVLYHLAVKAYNSAG 884
Query: 1079 TSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY 1138
T PS + + T + PP P N+ + +S++ + L W + ++ E GYK+ Y
Sbjct: 885 TG-PSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALD--NESEVKGYKVLY 940
Query: 1139 SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTV-------V 1191
+ ++ + VE ++ +Y ++++ F+ G G S+ +
Sbjct: 941 RWNRQSSTSVIETNKTSVELSLPFDE-----DYIIEIKPFSDGGDGSSSEQIRIPKISNA 995
Query: 1192 GRTRESVPSSGPTNVSALATTSSSMLVRWS 1221
+S +SA++T S+ R S
Sbjct: 996 YARGSGASTSNACTLSAISTIMISLTARSS 1025
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 282 bits (722), Expect = 2e-75
Identities = 245/954 (25%), Positives = 408/954 (42%), Gaps = 66/954 (6%)
Query: 17 AARAQDDVSPYFKTEPVRTQVHLEGN--RLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY 74
A +Q P F+ +P+ E +++L C A S P ++W N E+ K
Sbjct: 28 ALGSQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEM-KLEPGS 86
Query: 75 RYMITS--------LDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSH 126
R+ + AG Y+C+ N +G ++ R+ ++ ++ F + E+ +H
Sbjct: 87 RHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAH 146
Query: 127 -GEAAVIRAPRIASFPQPQVTWFRDG--RKIPPSSRIAIT-LENTLVILSTVAPDAGRYY 182
G ++ A +P W + IP R ++ L I T A D G Y
Sbjct: 147 EGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYS 206
Query: 183 VQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIP-PKNTSVVAGTSEVTLECVANA 241
A + + K+ + AP+I P T + G +VTLEC A
Sbjct: 207 CLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVG-QQVTLECFAFG 265
Query: 242 RPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 301
P+ ++ W+K LS + L IP+ + D G YECEA +S V+G
Sbjct: 266 NPVPRIK--WRKVDGSLSPQWTTAEPTLQIPSVSFEDEGTYECEA--ENSKGRDTVQGRI 321
Query: 302 LSVLEPP--QFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKD----AAVVEVEKLT 355
+ +P + + + E I + + C A G P P++ W ++ A+ VE L
Sbjct: 322 IVQAQPEWLKVISDTEADIGSNLRW----GCAAAGKPRPTVRWLRNGEPLASQNRVEVLA 377
Query: 356 RFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTV-- 413
G L+ S L +D+GM+QC A N G + S LAV ++AP+ P+ +
Sbjct: 378 -------GDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPA 430
Query: 414 IDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTY 473
G +++ C+ AP+ + W KG IL + S R T G+L+I SD G Y
Sbjct: 431 ARGGEILIPCQPRAAPKAVVLWSKGTEILVNSS----RVTVTPDGTLIIRNISRSDEGKY 486
Query: 474 TCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
TC A N G ++ L V T+IT P + G ++ C +HDP + + + W
Sbjct: 487 TCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTL 546
Query: 534 DGATLGTES----HPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
D + + + R + G L I G YTC + + S+ A + VR
Sbjct: 547 DDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRG 606
Query: 589 LPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNA-PWTVLL---ASVD 644
P P V + + I L+W++ FD +SP+ +Y L+ A W + A+++
Sbjct: 607 PPGPPGGVV--VRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIE 664
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTN 704
A + V GL P Y+FR+ A N +G G+ S + ++ E P+ P + G
Sbjct: 665 GNAETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAP 724
Query: 705 QSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL--EDLIIWTN 762
+++ W P +QNG GY++ + G +Q + AD + E + +T
Sbjct: 725 GELIVNWTPMSREYQNGDGFGYLLSFRRQG-STHWQTARVPGADAQYFVYSNESVRPYTP 783
Query: 763 YEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFING 822
+E+++ +YN G G S ++ + P V P V A+ +S+ + TW P Q +NG
Sbjct: 784 FEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWE-PVQQDMNG 842
Query: 823 INQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPR 882
I GY++ W+ +E S VSGL T+Y +V + G GP
Sbjct: 843 ILLGYEIRYWKAGDKEAAADRVRTAGLDTSAR---VSGLHPNTKYHVTVRAYNRAGTGPA 899
Query: 883 STPQLVRTHEDVP-GPVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWE 933
S T + P P G++S++ +SL + W P +TGY++ ++
Sbjct: 900 SPSANATTMKPPPRRPPGNISWT-FSSSSLSIKWDPVVPFRNESAVTGYKMLYQ 952
Score = 160 bits (405), Expect = 1e-38
Identities = 120/417 (28%), Positives = 196/417 (47%), Gaps = 38/417 (9%)
Query: 1360 YTATGLKPESVYLFRITAQTRKGWGEAAEALVV--------TTEKRDRPQPPSRPMVQQE 1411
Y T +K L + AQ R G A V T R P PP +V+
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVR-- 617
Query: 1412 DVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWA---LHSASVSHNASSFIVDRLKP 1468
D+ ++ LSW G D SP+ YT+Q R P+G+W + A++ NA + V L P
Sbjct: 618 DIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQVLGLTP 677
Query: 1469 FTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAED 1528
+ Y+FRV A+N +G E S S + T +AAP AP+ LS +++ W P + +
Sbjct: 678 WMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSRE 737
Query: 1529 KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDN 1588
NG G+ + +R +G + + PGA + Y + Y ++
Sbjct: 738 YQNGDGFGYLLSFRR---QGSTHWQTARV--PGA-----DAQYFV----------YSNES 777
Query: 1589 LNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPP 1648
+ + +E+++ YN G+GP S V+ E P AP V G ++++++VTWEP
Sbjct: 778 VRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQ 837
Query: 1649 LDSQNGDIQGYKIYFWEA-QRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG 1707
D NG + GY+I +W+A + +RV+T L + S ++ L T Y V+V A+N AG
Sbjct: 838 QD-MNGILLGYEIRYWKAGDKEAAADRVRTAGL-DTSARVSGLHPNTKYHVTVRAYNRAG 895
Query: 1708 DGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE--APQFPNGILEGYRLVYE 1762
GP S T + P P +++S+++ W+ P + GY+++Y+
Sbjct: 896 TGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQ 952
Score = 149 bits (376), Expect = 3e-35
Identities = 130/485 (26%), Positives = 215/485 (44%), Gaps = 46/485 (9%)
Query: 880 GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTN 939
G T Q +H+ P L+F+ LD + + +PG Y RTN
Sbjct: 523 GDNLTLQCHASHD----PTMDLTFTWTLD-DFPIDFDKPGG-------------HYRRTN 564
Query: 940 TRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV-SASTISSGVPPELPGPPTN 998
+ T + LT L T Q V SAS ++ + PGPP
Sbjct: 565 VKET-----------IGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGG 613
Query: 999 LGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEV 1058
+ + +IG ++ L + G+D + I+++ ++A+ G+ ++ + + + E +A + +V
Sbjct: 614 VVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQ-VRTNPANIEGNAETAQV 672
Query: 1059 PDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWM 1118
L P+ Y FR+ NI+GT PS PS KI+T +A P +AP+ +S + L + W
Sbjct: 673 LGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWT 732
Query: 1119 PLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQA 1177
P+ NG + GY + + R H +T D Y+ E + +T + V++++
Sbjct: 733 PMSREYQNG--DGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRS 790
Query: 1178 FNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKV 1237
+N G GP S T + + E P PT V A +SS M V W V + D NG++LGY++
Sbjct: 791 YNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPV-QQDMNGILLGYEI 849
Query: 1238 MYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTL 1297
Y + + SA+++GL Y V V A+ R G G P+ P T+
Sbjct: 850 RYWKAGDKEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTG-PASPSANATTM 908
Query: 1298 DDVPGPPMGILFPEVRTTSVRLIWQP------PAAPNGIILAYQ----ITHRLNTTTANT 1347
P P G + ++S+ + W P +A G + YQ +T L+ T N
Sbjct: 909 KPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQNDLHLTPTLHLTGKNW 968
Query: 1348 ATVEV 1352
+ V
Sbjct: 969 IEIPV 973
Score = 76.6 bits (187), Expect = 2e-13
Identities = 79/305 (25%), Positives = 139/305 (45%), Gaps = 22/305 (7%)
Query: 1253 VEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPG-PPMGILFPE 1311
+EGN+ +AQ+ GL ++ YE +V+A +G G PS P RT + P P G+
Sbjct: 663 IEGNAE-TAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGG 721
Query: 1312 VRTTSVRLIWQPPAAP--NGIILAYQITHRLNTTTA-NTATVEVLAPSARQYTATGLKPE 1368
+ + W P + NG Y ++ R +T TA V Y+ ++P
Sbjct: 722 GAPGELIVNWTPMSREYQNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPY 781
Query: 1369 SVYLFRITAQTRKGWG-EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSD 1427
+ + +I + R+G G E+ ALV + E+ R P V + V + + ++WEP
Sbjct: 782 TPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTK---VWAKGVSSSEMNVTWEPVQQ 838
Query: 1428 GLS------PVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND 1481
++ +RY+ +E + R + +A + +A V L P T Y V+A N
Sbjct: 839 DMNGILLGYEIRYWKAGDKEAAADR--VRTAGLDTSAR---VSGLHPNTKYHVTVRAYNR 893
Query: 1482 IGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRY 1541
G S S + TT++ P P +S T +++S+ I+W P + + G+++ Y
Sbjct: 894 AGTGPASP-SANATTMKPPPRRPPGNISWT-FSSSSLSIKWDPVVPFRNESAVTGYKMLY 951
Query: 1542 RELLY 1546
+ L+
Sbjct: 952 QNDLH 956
Score = 63.5 bits (153), Expect = 2e-09
Identities = 42/132 (31%), Positives = 62/132 (46%), Gaps = 9/132 (6%)
Query: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRY--SSAIAIHWSSGDPGKGPIT 1855
++ A+T EA V G PGPPG ++VR + I + WS G PI
Sbjct: 584 KYTCMAQTVVDSASKEATVLV---RGPPGPPG-GVVVRDIGDTTIQLSWSRGFDNHSPIA 639
Query: 1856 RYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDIL--KPGVSYDFRVIAVNDYGFGTPSS 1913
+Y ++AR G W ++ P + + +L P + Y+FRVIA N G G PS
Sbjct: 640 KYTLQARTPPAGKWK-QVRTNPANIEGNAETAQVLGLTPWMDYEFRVIASNILGTGEPSG 698
Query: 1914 PSQSVPAQKANP 1925
PS + ++A P
Sbjct: 699 PSSKIRTREAAP 710
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 275 bits (703), Expect = 4e-73
Identities = 263/1007 (26%), Positives = 415/1007 (41%), Gaps = 59/1007 (5%)
Query: 7 WTLLALHQIRAARAQD-DVSPYFKTEP--VRTQVHLEGNRLVLTCMAEGSWPLEFKWLHN 63
W L+ + ++ D P F EP + + ++ L C G+ ++WL N
Sbjct: 5 WKLMLFLSVTMCLSESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRN 64
Query: 64 NRELTKFSLEYRYMITS--------LDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSF 115
E+ S +YRY + + +G Y+C+ N +G++L R+ +Q AY+G+F
Sbjct: 65 GTEIDLES-DYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNF 123
Query: 116 EEGEKHQ-SVSHGEAAVIRAPRIASFPQPQVTW-FRDGRK-IPPSSRIAITLENTLVILS 172
+ SV G+ V+ P+ +W F + + SR I+ E + +S
Sbjct: 124 SGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYIS 183
Query: 173 TV-APDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTS 231
V D G Y N S P LT+ N G + P I + T A +
Sbjct: 184 KVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGE-YEPKIEVHFPFTVTAAKGT 242
Query: 232 EVTLECVANARPLIKLHIIWKK-DGVLLSGG-ISDHNRRLTIPNPTGSDAGYYECEAVLR 289
V +EC A P+ I W K +G + S + L IPN DAG YEC A
Sbjct: 243 TVKMECFALGNPVPT--ITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRA--E 298
Query: 290 SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
+S + RG L V P +V E + + C+A G P P+ W K+ V
Sbjct: 299 NSRGKNSFRGQ-LQVYTYPHWV-EKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNG--V 354
Query: 350 EVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL 409
+ +R N G L I + D GM+QC A N G + S L + + AP L
Sbjct: 355 PLSPQSRVEMVN-GVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQL 413
Query: 410 DSTVI--DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHI 467
T+I VV+ C+ G+P+P I+W+KG+R + R L GSL I
Sbjct: 414 KKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENK----RIAILPDGSLRILNASK 469
Query: 468 SDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTI 527
SD G Y C N G E A L V TRI P+ + G + C HD + +
Sbjct: 470 SDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDV 529
Query: 528 RYIWEKDGATLGTESH----PRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSA 582
+ W G + E IR + + L I G Y CRV + + S A
Sbjct: 530 TFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEA 589
Query: 583 HLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEM-SENNAPWTVLLA 641
L VR P P + + + L+W+ D +SP+ Y L+ S + W +
Sbjct: 590 ELLVRGPPGPPG--IVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKT 647
Query: 642 S---VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698
+ S L P Y+FR+ A N +G G S + + E P P NV
Sbjct: 648 VPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVS 707
Query: 699 ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758
++I W+P E QNG GYI+ + G G++ K +T ++ + + D
Sbjct: 708 GRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDES 766
Query: 759 I--WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
+ T +E++V YN+ G G +S V + +G P+ P +V A + + + I W
Sbjct: 767 VPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK 826
Query: 817 PQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTT 876
G QG+++ W+ + E+E T T + +S + ++GL+ T Y +V +
Sbjct: 827 ESL--GRPQGFEVGYWK-DMEQEDTAETVKTRGNESFVI--LTGLEGNTLYHFTVRAYNG 881
Query: 877 PGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWEE 934
G GP S+ T + P E + + + W+ P + GY++ + +
Sbjct: 882 AGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQ 941
Query: 935 YNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA 981
+N++V + L+ V L Y IEV A + G G S+
Sbjct: 942 EGHSNSQV---IETQKLQ-AVVPLPDAGVYIIEVRAYSEGGDGTASS 984
Score = 142 bits (357), Expect = 5e-33
Identities = 114/384 (29%), Positives = 185/384 (48%), Gaps = 38/384 (9%)
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPS 1444
+ AE LV R P PP +V E++ + LSW P +D SP+ Y +Q R S
Sbjct: 587 DEAELLV-----RGPPGPPGIVIV--EEITESTATLSWSPAADNHSPISSYNLQARSPFS 639
Query: 1445 GRWALHSAS---VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
W ++ + S + L P+ Y+FRV ATN IG + S S + T +A P
Sbjct: 640 LGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVP 699
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
APT +S ++I W+P +E+ NG G+ + +R G RG+ + + +
Sbjct: 700 KTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRP---NGTRGWKEKMVTSSE 756
Query: 1562 ATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEA 1621
A S + R+ S P LT +E+++ VYN G+GP S + E
Sbjct: 757 A------SKFIYRDESVPPLTP-----------FEVKVGVYNNKGDGPFSQIVVICSAEG 799
Query: 1622 VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFW-EAQRGNLTERVKTLFL 1680
P+AAP +V + +++ V W+ + G QG+++ +W + ++ + E VKT
Sbjct: 800 EPSAAPTDVKATSVSVSEILVAWK--HIKESLGRPQGFEVGYWKDMEQEDTAETVKTRG- 856
Query: 1681 AENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPS-APSSVKFSELTTTS 1739
E+ V L L G T Y +V A+N AG GP S+ T+++ PS APS++++ E +
Sbjct: 857 NESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRW-EQQGSQ 915
Query: 1740 VNVSWE--APQFPNGILEGYRLVY 1761
V++ WE P + GY++ Y
Sbjct: 916 VSLGWEPVIPLANESEVVGYKVFY 939
Score = 139 bits (351), Expect = 2e-32
Identities = 118/408 (28%), Positives = 180/408 (44%), Gaps = 24/408 (5%)
Query: 993 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
PGPP + + I + TL + P D + IS + ++A+ + + ++ D
Sbjct: 597 PGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITG-D 655
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS 1112
S DLNP+ Y FR+ N +GT PS PSR I+T +A P AP NVS R+
Sbjct: 656 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHE 715
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER-DYTIEDLEEWTEY 1171
L + W P+ E NG E GY + + + G V + Y E + T +
Sbjct: 716 LVIAWEPVSEEFQNG--EGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPF 773
Query: 1172 RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGL 1231
V+V +N G GP+SQ VV + E PS+ PT+V A + + S +LV W + E+ G
Sbjct: 774 EVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKES--LGR 831
Query: 1232 VLGYKVMY-KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP 1290
G++V Y K+ + + GN S LTGL LY V A+ G G PS
Sbjct: 832 PQGFEVGYWKDMEQEDTAETVKTRGNES-FVILTGLEGNTLYHFTVRAYNGAGYGPPS-S 889
Query: 1291 PILERTLDDVPGPPMGILFPEVRTTSVRLIWQP--PAAPNGIILAYQITHR----LNTTT 1344
+ T P L E + + V L W+P P A ++ Y++ +R N+
Sbjct: 890 EVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHSNSQV 949
Query: 1345 ANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
T ++ + P L VY+ + A + G G A+ + V
Sbjct: 950 IETQKLQAVVP---------LPDAGVYIIEVRAYSEGGDGTASSQIRV 988
Score = 138 bits (347), Expect = 7e-32
Identities = 235/1057 (22%), Positives = 403/1057 (38%), Gaps = 115/1057 (10%)
Query: 208 GPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNR 267
GP P II P ++ +V L C P+ W ++G + SD+
Sbjct: 24 GPVFVQEPDDIIFPTDSD----EKKVALNCEVRGNPVPSYR--WLRNGTEIDLE-SDYRY 76
Query: 268 RLT-----IPNPT-GSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAE 321
L I NP+ D+G+Y+C A S+ S R A L F ++
Sbjct: 77 SLIDGTFIISNPSEAKDSGHYQCLATNTVGSILS--REATLQFAYLGNFSGRTRSAVSVR 134
Query: 322 MEKVVDIPCQAKGVPPPSI-TW-YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQ 379
+ V + C P I +W + + E RF + G L IS + D G +
Sbjct: 135 EGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYI 194
Query: 380 CFARNAAGEVQTSTYLAVTSIAPNITRG----------PLDSTVIDGMSVVLACETSGAP 429
C +N + + ++ + G P T G +V + C G P
Sbjct: 195 CLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNP 254
Query: 430 RPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASAD 489
P ITW K +G + L I + DAG Y C A NSRG +
Sbjct: 255 VPTITWMK-----VNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQ 309
Query: 490 LVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD 549
L V+ + D + G+ C T PR T R W K+G L +S +
Sbjct: 310 LQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMV-- 365
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAIN 609
NG L I D G Y C + G SA L++ L AP + L ++ I
Sbjct: 366 -NGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI--LASAPTFALNQL----KKTII 418
Query: 610 LTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVK-GLVPARSYQFRLCAV 668
+T + ++E +P + +A + ++P S + +
Sbjct: 419 VTKDQ---------EVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASK 469
Query: 669 NDVGK------GQFSKDTERVSLPEEPPT----APPQNVIASGRTNQSIMIQWQPPPESH 718
+D GK F SL + PT P + + G +SI++ + ++
Sbjct: 470 SDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVG---ESIVLNCKAIHDAS 526
Query: 719 QNGILKGYIIRYCLAGLPVGYQ-----FKNI-TDADVNNLLLEDLIIWTNYEIEVAAYNS 772
+ + L G P+ ++ F++I A +L++ ++++ +
Sbjct: 527 LD-----VTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTT 581
Query: 773 AGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAW 832
A S E ++G P PPG V E +T +W+ P+ + I+ Y L A
Sbjct: 582 ADS---VSDEAELLVRGPPG-PPGIVIVEEITESTATLSWS-PAADNHSPISS-YNLQAR 635
Query: 833 EPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTP-QLVRTH 891
P T+ T + L + EY V+ G G STP +++RT+
Sbjct: 636 SPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTN 695
Query: 892 EDVPGPVG-HLSFSEILDTSLKVSWQEPGEK--NGILTGYRIS--------WEEYNRTNT 940
E VP ++S L ++W+ E+ NG GY ++ W+E T++
Sbjct: 696 EAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSS 755
Query: 941 RVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLG 1000
+ ++ YR + LT + ++V +KG G S + E PT++
Sbjct: 756 EASKFI------YRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVK 809
Query: 1001 ISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPD 1060
+++ + + ++ K S+ R +VG + E+ + + + +
Sbjct: 810 ATSVSVSEILVAWK---HIKESLGR-PQGFEVGYWKDMEQEDTAETVKTRGNESFVILTG 865
Query: 1061 LNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPL 1120
L T Y F +R N G PPS T ++PP AP+N+ + + L W P+
Sbjct: 866 LEGNTLYHFTVRAYNGAGYGPPSS-EVSATTKKSPPSQAPSNLRWEQQG-SQVSLGWEPV 923
Query: 1121 PEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNA 1180
+ E VGYK+ Y R +GH S V++ ++ + L + Y ++V+A++
Sbjct: 924 --IPLANESEVVGYKVFY-RQEGHSN--SQVIE--TQKLQAVVPLPDAGVYIIEVRAYSE 976
Query: 1181 IGSGPWSQTV-VGRTRESVPSSGPTNVSALATTSSSM 1216
G G S + V +S + + +L+T+SSS+
Sbjct: 977 GGDGTASSQIRVPSYSGGKITSAQSTLHSLSTSSSSV 1013
Score = 95.1 bits (235), Expect = 7e-19
Identities = 100/453 (22%), Positives = 179/453 (39%), Gaps = 45/453 (9%)
Query: 1301 PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR----LNTTTANTATVEVLAPS 1356
PGPP ++ E+ ++ L W P A + I +Y + R L T T E++
Sbjct: 597 PGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVP-EIITGD 655
Query: 1357 ARQYTATGLKPESVYLFRITAQTRKGWGEAA--EALVVTTEKRDRPQPPSRPMVQQEDVR 1414
A L P Y FR+ A G G+ + ++ T E + P + V R
Sbjct: 656 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTN---VSGRSGR 712
Query: 1415 ARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASV-SHNASSFIV--DRLKPFTS 1471
++++WEP S+ + P+G V S AS FI + + P T
Sbjct: 713 RHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTP 772
Query: 1472 YKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKIN 1531
++ +V N+ GD FS+ + + + P APT + T + + +L+ W+ E
Sbjct: 773 FEVKVGVYNNKGDGPFSQ-IVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESL-- 829
Query: 1532 GILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL-SRPSLTQYELDNLN 1590
G GF + Y W ++ + + +R + + L L
Sbjct: 830 GRPQGFEVGY----------------------WKDMEQEDTAETVKTRGNESFVILTGLE 867
Query: 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+ Y + YN G GP S ++ P+ AP N+ +Q+ + WEP
Sbjct: 868 GNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWE-QQGSQVSLGWEPVIPL 926
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
+ ++ GYK+++ Q G+ +V + V L + Y++ V A++ GDG
Sbjct: 927 ANESEVVGYKVFY--RQEGHSNSQVIETQKLQAVVPLPDA---GVYIIEVRAYSEGGDGT 981
Query: 1711 RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVS 1743
S+ + + + L+T+S +V+
Sbjct: 982 ASSQIRVPSYSGGKITSAQSTLHSLSTSSSSVT 1014
Score = 92.0 bits (227), Expect = 6e-18
Identities = 82/349 (23%), Positives = 144/349 (41%), Gaps = 22/349 (6%)
Query: 1086 SRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPL-----PEMEYN---GNPESVGYKIK 1137
S + + L P P V + +E++ L W P P YN +P S+G++
Sbjct: 586 SDEAELLVRGPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTV 645
Query: 1138 YSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRE 1196
KT+ ++ +E + DL W EY +V A N IG+G P + + + RT E
Sbjct: 646 --------KTVPEIITGDMESAMAV-DLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNE 696
Query: 1197 SVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN 1256
+VP + PTNVS + +++ W V E +NG GY V ++ + +
Sbjct: 697 AVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSE 756
Query: 1257 SSRSAQLT-GLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT 1315
+S+ + +EV+V + GDG S ++ + P + V +
Sbjct: 757 ASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVS 816
Query: 1316 SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRI 1375
+ + W+ G +++ + + +TA + TGL+ ++Y F +
Sbjct: 817 EILVAWKHIKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTV 876
Query: 1376 TAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP 1424
A G+G + + TT+K Q PS +Q+ V L WEP
Sbjct: 877 RAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQ---GSQVSLGWEP 922
Score = 62.4 bits (150), Expect = 5e-09
Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 9/132 (6%)
Query: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIA-IHWSSGDPGKGPITR 1856
R+ R +T EA + G PGPPG+ I+ + + A + WS PI+
Sbjct: 573 RYGCRVQTTADSVSDEAELLV---RGPPGPPGIVIVEEITESTATLSWSPAADNHSPISS 629
Query: 1857 YVIEARPSDEGLWDILIKDIPKEVSS---YTFSMDILKPGVSYDFRVIAVNDYGFGTPSS 1913
Y ++AR W +K +P+ ++ ++D L P V Y+FRV+A N G G PS+
Sbjct: 630 YNLQARSPFSLGWQT-VKTVPEIITGDMESAMAVD-LNPWVEYEFRVVATNPIGTGDPST 687
Query: 1914 PSQSVPAQKANP 1925
PS+ + +A P
Sbjct: 688 PSRMIRTNEAVP 699
Score = 43.5 bits (101), Expect = 0.002
Identities = 74/324 (22%), Positives = 121/324 (37%), Gaps = 40/324 (12%)
Query: 1623 PTAAPRNVVVHGATATQLDVTWEPP-----PLDSQNGDIQGYKIYFWEAQRGNLTERVKT 1677
P P V+V T + ++W P P+ S N + W+ + V
Sbjct: 596 PPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQT-----VKTVPE 650
Query: 1678 LFLAE-NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQG-QTQQAAP-SAPSSVKFSE 1734
+ + S +L + Y V A N G G STP++ +T +A P +AP++V
Sbjct: 651 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRS 710
Query: 1735 LTTTSVNVSWE--APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLA 1792
+ ++WE + +F NG GY + + P K+VT +D +
Sbjct: 711 GRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASK----FIYRDES 766
Query: 1793 EGVTYRFRIRAKTFTY---GPEIEANVT-TGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD 1848
F ++ + GP + V + GE + P V S I + W
Sbjct: 767 VPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK 826
Query: 1849 PGKGPITRYVIEARPS--DEGLW-DILIKDIPKEVSSYTFSMDILKPGVS----YDFRVI 1901
G RP + G W D+ +D + V + ++ G+ Y F V
Sbjct: 827 ESLG---------RPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVR 877
Query: 1902 AVNDYGFGTPSSPSQSVPAQKANP 1925
A N G+G PSS S +K+ P
Sbjct: 878 AYNGAGYGPPSS-EVSATTKKSPP 900
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 274 bits (701), Expect = 6e-73
Identities = 261/990 (26%), Positives = 409/990 (41%), Gaps = 58/990 (5%)
Query: 23 DVSPYFKTEP--VRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITS 80
D P F EP + + ++ L C G+ ++WL N E+ S +YRY +
Sbjct: 96 DYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLES-DYRYSLID 154
Query: 81 --------LDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQ-SVSHGEAAV 131
+ +G Y+C+ N +G++L R+ +Q AY+G+F + SV G+ V
Sbjct: 155 GTFIISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVV 214
Query: 132 IRAPRIASFPQPQVTW-FRDGRK-IPPSSRIAITLENTLVILSTV-APDAGRYYVQAVND 188
+ P+ +W F + + SR I+ E + +S V D G Y N
Sbjct: 215 LMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNT 274
Query: 189 KNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLH 248
S P LT+ N G + P I + T A + V +EC A P+
Sbjct: 275 VTNARVLSPPTPLTLRNDGVMGE-YEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT-- 331
Query: 249 IIWKK-DGVLLSGG-ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLE 306
I W K +G + S + L IPN DAG YEC A +S + RG L V
Sbjct: 332 ITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRA--ENSRGKNSFRGQ-LQVYT 388
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ 366
P +V E + + C+A G P P+ W K+ V + +R N G L
Sbjct: 389 YPHWV-EKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNG--VPLSPQSRVEMVN-GVLM 444
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI--DGMSVVLACE 424
I + D GM+QC A N G + S L + + AP L T+I VV+ C+
Sbjct: 445 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK 504
Query: 425 TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
G+P+P I+W+KG+R + R L GSL I SD G Y C N G
Sbjct: 505 PQGSPKPTISWKKGDRAVRENK----RIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESH- 543
E A L V TRI P+ + G + C HD + + + W G + E
Sbjct: 561 EIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEG 620
Query: 544 ---PRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVAT 599
IR + + L I G Y CRV + + S A L VR P P +
Sbjct: 621 GHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPG--IVI 678
Query: 600 LSTVERRAINLTWTKPFDGNSPLIRYILEM-SENNAPWTVLLAS---VDPKATSVTVKGL 655
+ + L+W+ D +SP+ Y L+ S + W + + S L
Sbjct: 679 VEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDL 738
Query: 656 VPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPP 715
P Y+FR+ A N +G G S + + E P P NV ++I W+P
Sbjct: 739 NPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVS 798
Query: 716 ESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII--WTNYEIEVAAYNSA 773
E QNG GYI+ + G G++ K +T ++ + + D + T +E++V YN+
Sbjct: 799 EEFQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNK 857
Query: 774 GLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWE 833
G G +S V + +G P+ P +V A + + + I W G QG+++ W+
Sbjct: 858 GDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESL--GRPQGFEVGYWK 915
Query: 834 PEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHED 893
+ E+E T T + +S + ++GL+ T Y +V + G GP S+ T +
Sbjct: 916 -DMEQEDTAETVKTRGNESFVI--LTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKS 972
Query: 894 VPGPVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTL 951
P E + + + W+ P + GY++ + + +N++V + L
Sbjct: 973 PPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHSNSQV---IETQKL 1029
Query: 952 EYRVTGLTALTTYTIEVAAMTSKGQGQVSA 981
+ V L Y IEV A + G G S+
Sbjct: 1030 Q-AVVPLPDAGVYIIEVRAYSEGGDGTASS 1058
Score = 142 bits (357), Expect = 5e-33
Identities = 114/384 (29%), Positives = 185/384 (48%), Gaps = 38/384 (9%)
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPS 1444
+ AE LV R P PP +V E++ + LSW P +D SP+ Y +Q R S
Sbjct: 661 DEAELLV-----RGPPGPPGIVIV--EEITESTATLSWSPAADNHSPISSYNLQARSPFS 713
Query: 1445 GRWALHSAS---VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
W ++ + S + L P+ Y+FRV ATN IG + S S + T +A P
Sbjct: 714 LGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVP 773
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
APT +S ++I W+P +E+ NG G+ + +R G RG+ + + +
Sbjct: 774 KTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRP---NGTRGWKEKMVTSSE 830
Query: 1562 ATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEA 1621
A S + R+ S P LT +E+++ VYN G+GP S + E
Sbjct: 831 A------SKFIYRDESVPPLTP-----------FEVKVGVYNNKGDGPFSQIVVICSAEG 873
Query: 1622 VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFW-EAQRGNLTERVKTLFL 1680
P+AAP +V + +++ V W+ + G QG+++ +W + ++ + E VKT
Sbjct: 874 EPSAAPTDVKATSVSVSEILVAWK--HIKESLGRPQGFEVGYWKDMEQEDTAETVKTRG- 930
Query: 1681 AENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPS-APSSVKFSELTTTS 1739
E+ V L L G T Y +V A+N AG GP S+ T+++ PS APS++++ E +
Sbjct: 931 NESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRW-EQQGSQ 989
Query: 1740 VNVSWE--APQFPNGILEGYRLVY 1761
V++ WE P + GY++ Y
Sbjct: 990 VSLGWEPVIPLANESEVVGYKVFY 1013
Score = 139 bits (351), Expect = 2e-32
Identities = 118/408 (28%), Positives = 180/408 (44%), Gaps = 24/408 (5%)
Query: 993 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
PGPP + + I + TL + P D + IS + ++A+ + + ++ D
Sbjct: 671 PGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITG-D 729
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS 1112
S DLNP+ Y FR+ N +GT PS PSR I+T +A P AP NVS R+
Sbjct: 730 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHE 789
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER-DYTIEDLEEWTEY 1171
L + W P+ E NG E GY + + + G V + Y E + T +
Sbjct: 790 LVIAWEPVSEEFQNG--EGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPF 847
Query: 1172 RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGL 1231
V+V +N G GP+SQ VV + E PS+ PT+V A + + S +LV W + E+ G
Sbjct: 848 EVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKES--LGR 905
Query: 1232 VLGYKVMY-KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP 1290
G++V Y K+ + + GN S LTGL LY V A+ G G PS
Sbjct: 906 PQGFEVGYWKDMEQEDTAETVKTRGNES-FVILTGLEGNTLYHFTVRAYNGAGYGPPS-S 963
Query: 1291 PILERTLDDVPGPPMGILFPEVRTTSVRLIWQP--PAAPNGIILAYQITHR----LNTTT 1344
+ T P L E + + V L W+P P A ++ Y++ +R N+
Sbjct: 964 EVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHSNSQV 1023
Query: 1345 ANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
T ++ + P L VY+ + A + G G A+ + V
Sbjct: 1024 IETQKLQAVVP---------LPDAGVYIIEVRAYSEGGDGTASSQIRV 1062
Score = 138 bits (347), Expect = 7e-32
Identities = 235/1057 (22%), Positives = 403/1057 (38%), Gaps = 115/1057 (10%)
Query: 208 GPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNR 267
GP P II P ++ +V L C P+ W ++G + SD+
Sbjct: 98 GPVFVQEPDDIIFPTDSD----EKKVALNCEVRGNPVPSYR--WLRNGTEIDLE-SDYRY 150
Query: 268 RLT-----IPNPT-GSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAE 321
L I NP+ D+G+Y+C A S+ S R A L F ++
Sbjct: 151 SLIDGTFIISNPSEAKDSGHYQCLATNTVGSILS--REATLQFAYLGNFSGRTRSAVSVR 208
Query: 322 MEKVVDIPCQAKGVPPPSI-TW-YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQ 379
+ V + C P I +W + + E RF + G L IS + D G +
Sbjct: 209 EGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYI 268
Query: 380 CFARNAAGEVQTSTYLAVTSIAPNITRG----------PLDSTVIDGMSVVLACETSGAP 429
C +N + + ++ + G P T G +V + C G P
Sbjct: 269 CLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNP 328
Query: 430 RPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASAD 489
P ITW K +G + L I + DAG Y C A NSRG +
Sbjct: 329 VPTITWMK-----VNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQ 383
Query: 490 LVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD 549
L V+ + D + G+ C T PR T R W K+G L +S +
Sbjct: 384 LQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMV-- 439
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAIN 609
NG L I D G Y C + G SA L++ L AP + L ++ I
Sbjct: 440 -NGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI--LASAPTFALNQL----KKTII 492
Query: 610 LTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVK-GLVPARSYQFRLCAV 668
+T + ++E +P + +A + ++P S + +
Sbjct: 493 VTKDQ---------EVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASK 543
Query: 669 NDVGK------GQFSKDTERVSLPEEPPT----APPQNVIASGRTNQSIMIQWQPPPESH 718
+D GK F SL + PT P + + G +SI++ + ++
Sbjct: 544 SDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVG---ESIVLNCKAIHDAS 600
Query: 719 QNGILKGYIIRYCLAGLPVGYQ-----FKNI-TDADVNNLLLEDLIIWTNYEIEVAAYNS 772
+ + L G P+ ++ F++I A +L++ ++++ +
Sbjct: 601 LD-----VTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTT 655
Query: 773 AGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAW 832
A S E ++G P PPG V E +T +W+ P+ + I+ Y L A
Sbjct: 656 ADS---VSDEAELLVRGPPG-PPGIVIVEEITESTATLSWS-PAADNHSPISS-YNLQAR 709
Query: 833 EPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTP-QLVRTH 891
P T+ T + L + EY V+ G G STP +++RT+
Sbjct: 710 SPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTN 769
Query: 892 EDVPGPVG-HLSFSEILDTSLKVSWQEPGEK--NGILTGYRIS--------WEEYNRTNT 940
E VP ++S L ++W+ E+ NG GY ++ W+E T++
Sbjct: 770 EAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSS 829
Query: 941 RVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLG 1000
+ ++ YR + LT + ++V +KG G S + E PT++
Sbjct: 830 EASKFI------YRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVK 883
Query: 1001 ISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPD 1060
+++ + + ++ K S+ R +VG + E+ + + + +
Sbjct: 884 ATSVSVSEILVAWK---HIKESLGR-PQGFEVGYWKDMEQEDTAETVKTRGNESFVILTG 939
Query: 1061 LNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPL 1120
L T Y F +R N G PPS T ++PP AP+N+ + + L W P+
Sbjct: 940 LEGNTLYHFTVRAYNGAGYGPPSS-EVSATTKKSPPSQAPSNLRWEQQG-SQVSLGWEPV 997
Query: 1121 PEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNA 1180
+ E VGYK+ Y R +GH S V++ ++ + L + Y ++V+A++
Sbjct: 998 --IPLANESEVVGYKVFY-RQEGHSN--SQVIE--TQKLQAVVPLPDAGVYIIEVRAYSE 1050
Query: 1181 IGSGPWSQTV-VGRTRESVPSSGPTNVSALATTSSSM 1216
G G S + V +S + + +L+T+SSS+
Sbjct: 1051 GGDGTASSQIRVPSYSGGKITSAQSTLHSLSTSSSSV 1087
Score = 95.1 bits (235), Expect = 7e-19
Identities = 100/453 (22%), Positives = 179/453 (39%), Gaps = 45/453 (9%)
Query: 1301 PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR----LNTTTANTATVEVLAPS 1356
PGPP ++ E+ ++ L W P A + I +Y + R L T T E++
Sbjct: 671 PGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVP-EIITGD 729
Query: 1357 ARQYTATGLKPESVYLFRITAQTRKGWGEAA--EALVVTTEKRDRPQPPSRPMVQQEDVR 1414
A L P Y FR+ A G G+ + ++ T E + P + V R
Sbjct: 730 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTN---VSGRSGR 786
Query: 1415 ARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASV-SHNASSFIV--DRLKPFTS 1471
++++WEP S+ + P+G V S AS FI + + P T
Sbjct: 787 RHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTP 846
Query: 1472 YKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKIN 1531
++ +V N+ GD FS+ + + + P APT + T + + +L+ W+ E
Sbjct: 847 FEVKVGVYNNKGDGPFSQ-IVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESL-- 903
Query: 1532 GILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL-SRPSLTQYELDNLN 1590
G GF + Y W ++ + + +R + + L L
Sbjct: 904 GRPQGFEVGY----------------------WKDMEQEDTAETVKTRGNESFVILTGLE 941
Query: 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+ Y + YN G GP S ++ P+ AP N+ +Q+ + WEP
Sbjct: 942 GNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWE-QQGSQVSLGWEPVIPL 1000
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
+ ++ GYK+++ Q G+ +V + V L + Y++ V A++ GDG
Sbjct: 1001 ANESEVVGYKVFY--RQEGHSNSQVIETQKLQAVVPLPDA---GVYIIEVRAYSEGGDGT 1055
Query: 1711 RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVS 1743
S+ + + + L+T+S +V+
Sbjct: 1056 ASSQIRVPSYSGGKITSAQSTLHSLSTSSSSVT 1088
Score = 92.0 bits (227), Expect = 6e-18
Identities = 82/349 (23%), Positives = 144/349 (41%), Gaps = 22/349 (6%)
Query: 1086 SRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPL-----PEMEYN---GNPESVGYKIK 1137
S + + L P P V + +E++ L W P P YN +P S+G++
Sbjct: 660 SDEAELLVRGPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTV 719
Query: 1138 YSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRE 1196
KT+ ++ +E + DL W EY +V A N IG+G P + + + RT E
Sbjct: 720 --------KTVPEIITGDMESAMAV-DLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNE 770
Query: 1197 SVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN 1256
+VP + PTNVS + +++ W V E +NG GY V ++ + +
Sbjct: 771 AVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSE 830
Query: 1257 SSRSAQLT-GLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT 1315
+S+ + +EV+V + GDG S ++ + P + V +
Sbjct: 831 ASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVS 890
Query: 1316 SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRI 1375
+ + W+ G +++ + + +TA + TGL+ ++Y F +
Sbjct: 891 EILVAWKHIKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTV 950
Query: 1376 TAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP 1424
A G+G + + TT+K Q PS +Q+ V L WEP
Sbjct: 951 RAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQ---GSQVSLGWEP 996
Score = 62.4 bits (150), Expect = 5e-09
Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 9/132 (6%)
Query: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIA-IHWSSGDPGKGPITR 1856
R+ R +T EA + G PGPPG+ I+ + + A + WS PI+
Sbjct: 647 RYGCRVQTTADSVSDEAELLV---RGPPGPPGIVIVEEITESTATLSWSPAADNHSPISS 703
Query: 1857 YVIEARPSDEGLWDILIKDIPKEVSS---YTFSMDILKPGVSYDFRVIAVNDYGFGTPSS 1913
Y ++AR W +K +P+ ++ ++D L P V Y+FRV+A N G G PS+
Sbjct: 704 YNLQARSPFSLGWQT-VKTVPEIITGDMESAMAVD-LNPWVEYEFRVVATNPIGTGDPST 761
Query: 1914 PSQSVPAQKANP 1925
PS+ + +A P
Sbjct: 762 PSRMIRTNEAVP 773
Score = 43.5 bits (101), Expect = 0.002
Identities = 74/324 (22%), Positives = 121/324 (37%), Gaps = 40/324 (12%)
Query: 1623 PTAAPRNVVVHGATATQLDVTWEPP-----PLDSQNGDIQGYKIYFWEAQRGNLTERVKT 1677
P P V+V T + ++W P P+ S N + W+ + V
Sbjct: 670 PPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQT-----VKTVPE 724
Query: 1678 LFLAE-NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQG-QTQQAAP-SAPSSVKFSE 1734
+ + S +L + Y V A N G G STP++ +T +A P +AP++V
Sbjct: 725 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRS 784
Query: 1735 LTTTSVNVSWE--APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLA 1792
+ ++WE + +F NG GY + + P K+VT +D +
Sbjct: 785 GRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASK----FIYRDES 840
Query: 1793 EGVTYRFRIRAKTFTY---GPEIEANVT-TGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD 1848
F ++ + GP + V + GE + P V S I + W
Sbjct: 841 VPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK 900
Query: 1849 PGKGPITRYVIEARPS--DEGLW-DILIKDIPKEVSSYTFSMDILKPGVS----YDFRVI 1901
G RP + G W D+ +D + V + ++ G+ Y F V
Sbjct: 901 ESLG---------RPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVR 951
Query: 1902 AVNDYGFGTPSSPSQSVPAQKANP 1925
A N G+G PSS S +K+ P
Sbjct: 952 AYNGAGYGPPSS-EVSATTKKSPP 974
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 270 bits (690), Expect = 1e-71
Identities = 244/953 (25%), Positives = 418/953 (43%), Gaps = 78/953 (8%)
Query: 87 GFYRCIVRNRMGALLQRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQV 145
G YRC N++G + + E V + F +E V G+ V+ P +
Sbjct: 105 GKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHI 164
Query: 146 TWFR-DGRKIPPSSRIAITLENTLVILSTVAPDAGR-YYVQAVNDKNGDNKTSQPITLTV 203
W + I R+ ++ + L + D+ Y A + P+ LTV
Sbjct: 165 YWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTV 224
Query: 204 EN------------VGGPADPIA---PTIIIPP----KNTSVVAGTSEVTL-ECVANARP 243
+ +G A+ I P +++PP +S+ E+ L EC A P
Sbjct: 225 NSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLP 284
Query: 244 LIKLHIIWKKDGVLLSGGIS---DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA 300
++ W K G L G ++ + L I N + D G Y C A S+ + +
Sbjct: 285 TPQVD--WNKIGGDLPKGRETKENYGKTLKIENVSYQDKGNYRCTA---SNFLGTATHDF 339
Query: 301 YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTR---F 357
++ V EPP++ K+P+ + + + + C+A+G P P+I W + + V+ F
Sbjct: 340 HVIVEEPPRWTKKPQSAVYSTGSNGI-LLCEAEGEPQPTIKWRVNGSPVDNHPFAGDVVF 398
Query: 358 RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNI-TRGPLDSTVIDG 416
+ + + L P+ T ++QC A N G + + + V + P I T+ + + G
Sbjct: 399 PRE----ISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTKDGENYATVVG 454
Query: 417 MSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
S L CE +P ++WQK E + ++ R+ E+G+L I+ T DAG+Y+C
Sbjct: 455 YSAFLHCEFFASPEAVVSWQKVEEVKP---LEGRRYHIYENGTLQINRTTEEDAGSYSCW 511
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV--TIRYIWEKD 534
N+ G +A+L + T++ P++ + K + C D + +++ W KD
Sbjct: 512 VENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSWSKD 571
Query: 535 GATL---GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPH 591
G GTE RI +D +L IS D G Y C +A + + + V +P
Sbjct: 572 GEAFEINGTEDG-RIIID-GANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPD 629
Query: 592 APEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAP---WTVLLASVDPKAT 648
PE+ LS + R++ LTW D NS + YI+E N W L V K T
Sbjct: 630 PPEN--LHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEEL-TRVQGKKT 686
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+V + L P YQFR+ AVN+VG+ Q S+ ++ P P PQN+ + ++
Sbjct: 687 TVILP-LAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMI 745
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVA 768
I+W+P QNG Y + + G PV ++ + +T+ + L + ++ Y+++V
Sbjct: 746 IKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTN---HTLRVMTPAVYAPYDVKVQ 802
Query: 769 AYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYK 828
A N G G VT ++ + P P + NST ++ TW+ ++G +GY+
Sbjct: 803 AINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQ 862
Query: 829 LIAWEPE-------QEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGP 881
+ W+ + +EV ++ F + G V L F+E+ +VL + + G GP
Sbjct: 863 INWWKTKSLLDGRTHPKEVNIL----RFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGP 918
Query: 882 RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTR 941
S P + +T E VP L ++ + +SW P + NG LTGY + ++ N T
Sbjct: 919 ESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEI 978
Query: 942 VTHYLPNVTL----EYRVTGLTALTTYTIEVAAMTSKGQGQ---VSASTISSG 987
N+T + ++ L A T Y + A TS+G G+ +ST+ G
Sbjct: 979 GELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGKPITEESSTLGEG 1031
Score = 156 bits (395), Expect = 2e-37
Identities = 164/702 (23%), Positives = 285/702 (40%), Gaps = 133/702 (18%)
Query: 1398 DRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQ---TRELPSGRWALHSASV 1454
D P PP + + + RSV L+WE G+D S + Y ++ +E P GRW +
Sbjct: 626 DVPDPPENLHLSER--QNRSVRLTWEAGADHNSNISEYIVEFEGNKEEP-GRW--EELTR 680
Query: 1455 SHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHT 1514
+ ++ L PF Y+FRV A N++G S+ S+ S+ T AAPD P + V
Sbjct: 681 VQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQ 740
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMR 1574
++I+W+P + NG L +R+ ++ W E T
Sbjct: 741 PKEMIIKWEPLKSMEQNGPGLEYRVTWKP--------------QGAPVEWEEETVTNHTL 786
Query: 1575 NLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHG 1634
+ P++ + Y++++ N +G GP ++ GE P AP V+HG
Sbjct: 787 RVMTPAV----------YAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAP---VIHG 833
Query: 1635 A---TATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR----GNLTERVKTLFLA--ENSV 1685
+T + VTW P D +G ++GY+I +W+ + + V L + NS
Sbjct: 834 VDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSG 893
Query: 1686 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
+ +L ++ + ++V A+N+ G GP S P QT + P P+ +K ++ + +SW
Sbjct: 894 MVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWG 953
Query: 1746 APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNS-PLWLKVKDLAEGVTYRFRIRAK 1804
P+ NG L GY L Y+ + + ++ +++ S P W + +L Y+F +RA
Sbjct: 954 LPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPSW-HLSNLNATTKYKFYLRA- 1011
Query: 1805 TFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPS 1864
T G G P I SS + G G G I+
Sbjct: 1012 ------------CTSQGCGKP-------ITEESSTL----GEGSKGIGKISGV------- 1041
Query: 1865 DEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKAN 1924
++ T +++ +PG + R++ N +G S Q V +
Sbjct: 1042 --------------NLTQKTHPIEVFEPGAEHIVRLMTKN---WGDNDSIFQDVIETRGR 1084
Query: 1925 PF---YE----EWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGH 1977
+ Y+ + WF+ ++ + L+ +LLL + R + KY+ K K
Sbjct: 1085 EYAGLYDDISTQGWFIGLMCAIALLTLLLLTVCFVKRNRGGKYSVK------EKEDLHPD 1138
Query: 1978 SEMMSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDV--TKYND 2035
E+ S+ + +F G Y+ S +P GSL + D+ T+ D
Sbjct: 1139 PEIQSVKDETF--------------------GEYSDSDEKPLKGSLRSLNRDMQPTESAD 1178
Query: 2036 LI----PAESSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSF 2073
+ + +E S I GS + V+SN +F
Sbjct: 1179 SLVEYGEGDHGLFSEDGSFIGAYAGSKEKGSVESNGSSTATF 1220
Score = 149 bits (377), Expect = 2e-35
Identities = 138/491 (28%), Positives = 215/491 (43%), Gaps = 43/491 (8%)
Query: 907 LDTSLKVSWQEPGEK---NGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTT 963
L SLK+SW + GE NG G RI + N T + NVTLE + G+ +
Sbjct: 560 LKHSLKLSWSKDGEAFEINGTEDG-RIIIDGANLT-------ISNVTLEDQ--GIYCCSA 609
Query: 964 YTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSI 1023
+T SA+ I+ ++P PP NL +S RSV L + G D ++I
Sbjct: 610 HT-----------ALDSAADITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGADHNSNI 658
Query: 1024 SRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPS 1083
S ++VE + G EE +L+ ++ + L PF Y FR+ VN VG S PS
Sbjct: 659 SEYIVEFE----GNKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPS 714
Query: 1084 QPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG 1143
QPS +T A PD P N+ ++ + + ++W PL ME NG + Y++ +
Sbjct: 715 QPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNG--PGLEYRVTWKPQGA 772
Query: 1144 HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP 1203
+ V + R T + Y V+VQA N +GSGP Q+V + E P + P
Sbjct: 773 PVEWEEETVTNHTLRVMT---PAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAP 829
Query: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR---- 1259
S+ + V WS VP+ +G + GY++ + + S R E N R
Sbjct: 830 VIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQ 889
Query: 1260 --SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSV 1317
S + L + + + VLA+ G G S P I + T + VP P + +V +
Sbjct: 890 RNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQ-TPEGVPEQPTFLKVIKVDKDTA 948
Query: 1318 RLIWQPPAAPNGIILAYQITHRLNTTT---ANTATVEVLAPSARQYTATGLKPESVYLFR 1374
L W P NG + Y + +++ T + + PS + + L + Y F
Sbjct: 949 TLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFY 1008
Query: 1375 ITAQTRKGWGE 1385
+ A T +G G+
Sbjct: 1009 LRACTSQGCGK 1019
Score = 65.9 bits (159), Expect = 4e-10
Identities = 81/306 (26%), Positives = 117/306 (38%), Gaps = 35/306 (11%)
Query: 30 TEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTK--------FSLEYRYMITSL 81
T+ ++ V+ G+ +L C AEG KW N + F E + T+L
Sbjct: 350 TKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHPFAGDVVFPREISF--TNL 407
Query: 82 DRTHAGFYRCIVRNRMGALLQRQT--EVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIAS 139
H Y+C N G +L V V + ++GE + +V G +A + AS
Sbjct: 408 QPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTKDGENYATVV-GYSAFLHCEFFAS 466
Query: 140 FPQPQVTWFRDGRKIPPSSRIAITLEN-TLVILSTVAPDAGRYYVQAVNDKNGDNKTSQP 198
P+ V+W + P R EN TL I T DAG Y +N KT+
Sbjct: 467 -PEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWV---ENAIGKTAVT 522
Query: 199 ITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIK--LHIIWKKDGV 256
L + N A + + PKN + + L C + +K L + W KDG
Sbjct: 523 ANLDIRN--------ATKLRVSPKNPR-IPKLHMLELHCESKCDSHLKHSLKLSWSKDGE 573
Query: 257 LL------SGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQF 310
G I LTI N T D G Y C A S + + L V +PP+
Sbjct: 574 AFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPDPPEN 633
Query: 311 VKEPER 316
+ ER
Sbjct: 634 LHLSER 639
Score = 52.0 bits (123), Expect = 6e-06
Identities = 74/347 (21%), Positives = 121/347 (34%), Gaps = 48/347 (13%)
Query: 303 SVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND 362
SV + P +K+ + + ++ I C+AKG P P+ +W KD N
Sbjct: 30 SVQQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNS 89
Query: 363 GGLQI--SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSV 419
G +I G + G ++CFA N G + + P + +D V +G +
Sbjct: 90 GTFRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPI 149
Query: 420 VLACE-TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDA-GTYTCLA 477
VL C G P I W I Q R + G L + D+ Y C A
Sbjct: 150 VLPCNPPKGLPPLHIYWM---NIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFA 206
Query: 478 TNSR-------------------GVDEAS-------ADLVVWARTRITKPPQDQ------ 505
R D +S A+ + + ++ PP +
Sbjct: 207 AFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPTESGSESSI 266
Query: 506 SVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL--GTESHPRIRLDRNGSLHISQTWSGD 563
+++KG + C P T + W K G L G E+ + + +L I D
Sbjct: 267 TILKGEILLLECFAEGLP--TPQVDWNKIGGDLPKGRET----KENYGKTLKIENVSYQD 320
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINL 610
G Y C + G + H+ V + P + P + + + I L
Sbjct: 321 KGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILL 367
Score = 46.6 bits (109), Expect = 3e-04
Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 1814 ANVTTGPGEGAPGPP-GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDE--GLWD 1870
A++T P PP + + R + ++ + W +G I+ Y++E + E G W+
Sbjct: 617 ADITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWE 676
Query: 1871 ILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
L + K+ T + L P V Y FRVIAVN+ G PS PS A P
Sbjct: 677 ELTRVQGKK----TTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAP 727
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 264 bits (674), Expect = 8e-70
Identities = 290/1109 (26%), Positives = 466/1109 (42%), Gaps = 119/1109 (10%)
Query: 198 PITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVL 257
P + + V G P I P++ + ++G + C A P K I W K G
Sbjct: 16 PALVMLGLVAGAHGDSKPVFIKVPEDQTGLSG-GVASFVCQATGEP--KPRITWMKKGKK 72
Query: 258 LSGGISDHNRRLTIPNPTGS-----------DAGYYECEAVLRSSSVPSVVRGAYLSVLE 306
+S S + + GS D YEC A ++S+ + A LSVLE
Sbjct: 73 VS---SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTA---TNSLGEINTSAKLSVLE 126
Query: 307 ----PPQFVK---EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLT-RFR 358
PP F P+ + E + + C A G P P I+W+KD V+ R +
Sbjct: 127 EEQLPPGFPSIDMGPQLKVV-EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK 185
Query: 359 QRNDGGLQISGLVPDDTGMFQCFARNAAG---EVQTSTYLAVTSIAPNITRGPLDSTVID 415
Q G LQI D G ++C A N+AG + Y+ V +AP + P V+
Sbjct: 186 QLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP 245
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
G SV L C GAP P + W G +L + + G ++ +++ + YTC
Sbjct: 246 GGSVNLTCVAVGAPMPYVKWMMGAE-------ELTKEDEMPVGRNVLELSNVVRSANYTC 298
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 535
+A +S G+ EA+A + V A + KPP D V + T S+ + Y +
Sbjct: 299 VAISSLGMIEATAQVTVKA---LPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYR 355
Query: 536 ATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG--GNDSRSAHLRVRQLPHAP 593
A GTE P +D + S Y RV++ G S +R R AP
Sbjct: 356 AA-GTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAP 413
Query: 594 EHPVATLST--VERRAINLTWTKPFDGNSPLIRY-ILEMSENNAPWTVLLASVDPKATSV 650
P + + + + W P + N + Y + ++ P
Sbjct: 414 SSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLT 473
Query: 651 TVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQ 710
TV L+P +Y R+ A VG G S T +V + P A P + A ++ I +
Sbjct: 474 TVGSLLPGITYSLRVLAFTAVGDGPPSP-TIQVKTQQGVP-AQPADFQAEVESDTRIQLS 531
Query: 711 WQPPPESHQNGILKGYIIRYCL---AGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEV 767
W PP+ II Y L A Q K +T ++ LEDL T Y ++
Sbjct: 532 WLLPPQER--------IIMYELVYWAAEDEDQQHK-VTFDPTSSYTLEDLKPDTLYRFQL 582
Query: 768 AAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGI---- 823
AA + G+GV++ + T Q P+ PP V + STT+R +W P NG+
Sbjct: 583 AARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQY 642
Query: 824 NQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRS 883
+ Y+ + E V ++ + D + GL+K+TEY V T G GP S
Sbjct: 643 SVAYEAVDGEDRGRHVVDGISREHSSWDLV------GLEKWTEYRVWVRAHTDVGPGPES 696
Query: 884 TPQLVRTHEDVP-GPVGHLSFSEILDTSLKVSWQ--EPGEKNGILTGYRISWEEYNRTNT 940
+P LVRT EDVP GP + + T++ V W+ P +++G + GY++++
Sbjct: 697 SPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756
Query: 941 RVTHYLPNVTL----EYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPP 996
R + +V L E ++GLT TTY++ VAA T+KG G S I + +PG P
Sbjct: 757 RGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVT-TTGAVPGRP 815
Query: 997 TNLGISNIGPRSVTLQFRPGYDGKTSISRWLV------EAQVGVVGEGEEWLLIHQLSNE 1050
T + IS + LQ+ P + + + + EA+ + G+
Sbjct: 816 TMM-ISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGK----------- 863
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110
D + V L+ T Y FR+ N G + ++I+T + P P N+ + +
Sbjct: 864 -DDQHFTVTGLHKGTTYIFRLAAKNRAGLG--EEFEKEIRTPEDLPSGFPQNLHVTGLTT 920
Query: 1111 TSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTE 1170
++ L W P E NG + Y + + R + L ++ D +T+ L+ T
Sbjct: 921 STTELAWDPPVLAERNG--RIISYTVVF-RDINSQQELQNITTD---TRFTLTGLKPDTT 974
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
Y ++V+A+ + GSGP S ++ RT V N A +S+L+ W EVP++ ++
Sbjct: 975 YDIKVRAWTSKGSGPLSPSIQSRTM-PVEQVFAKNFRVAAAMKTSVLLSW-EVPDSYKS- 1031
Query: 1231 LVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
+ +K++Y + + V+G+S R
Sbjct: 1032 -AVPFKILYNGQSVE-------VDGHSMR 1052
Score = 212 bits (540), Expect = 3e-54
Identities = 199/766 (25%), Positives = 326/766 (42%), Gaps = 61/766 (7%)
Query: 890 THEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNV 949
T + +P P L +E TS+ ++W + +T Y I + T
Sbjct: 314 TVKALPKPPIDLVVTETTATSVTLTWDSGNSEP--VTYYGIQYRAAG-TEGPFQEVDGVA 370
Query: 950 TLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV 1009
T Y + GL+ + Y V A+ S G+G S + + PP + + ++
Sbjct: 371 TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTM 430
Query: 1010 TLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSF 1069
+Q+ P + + + V W N V L P YS
Sbjct: 431 LVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW----HKHNTDAGLLTTVGSLLPGITYSL 486
Query: 1070 RMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNP 1129
R+ VG PPS P+ +++T Q P PA+ S+T + L W+ LP E
Sbjct: 487 RVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQLSWL-LPPQE----- 538
Query: 1130 ESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQT 1189
+ Y++ Y ++ + H V YT+EDL+ T YR Q+ A + +G G ++ T
Sbjct: 539 RIIMYELVYWAAEDEDQ--QHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT 596
Query: 1190 VVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPR 1249
+ RT +S PS+ P V ++ S+++ V W P RNG++ Y V Y+ D + + R
Sbjct: 597 IEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGR 656
Query: 1250 FWLVEGNSSR--SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMG 1306
+V+G S S L GL K+ Y V V A T +G G P P+L RT +DVP GPP
Sbjct: 657 H-VVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG-PESSPVLVRTDEDVPSGPPRK 714
Query: 1307 ILFPEVRTTSVRLIWQ--PPAAPNGIILAYQITH-RLNTTTANTATV--EVLAPSARQYT 1361
+ + +T+V + W+ P+ +G I YQ+T+ RL + +V+ A++ T
Sbjct: 715 VEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETT 774
Query: 1362 ATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLS 1421
+GL PE+ Y + A T KG G ++ +VTT P RP + + LL
Sbjct: 775 ISGLTPETTYSVTVAAYTTKGDGARSKPKIVTT----TGAVPGRPTMMISTTAMNTALLQ 830
Query: 1422 WEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND 1481
W P + + Y +Q R ++ + F V L T+Y FR+ A N
Sbjct: 831 WHPPKELPGELLGYRLQYCRADEAR--PNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNR 888
Query: 1482 IGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRY 1541
G E E + + T + P P L VT TT++ + W PP + NG ++ + + +
Sbjct: 889 AGLGE--EFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF 946
Query: 1542 RELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSV 1601
R ++ S ++N++ T++ L L Y+I++
Sbjct: 947 R-----------------------DINSQQELQNITTD--TRFTLTGLKPDTTYDIKVRA 981
Query: 1602 YNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPP 1647
+ + G GP SP + V +N V A T + ++WE P
Sbjct: 982 WTSKGSGPLSPSIQSRT-MPVEQVFAKNFRVAAAMKTSVLLSWEVP 1026
Score = 206 bits (524), Expect = 2e-52
Identities = 192/740 (25%), Positives = 316/740 (42%), Gaps = 78/740 (10%)
Query: 1203 PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQ 1262
P ++ TT++S+ + W ++ + V Y + Y+ + T+ F V+G ++
Sbjct: 322 PIDLVVTETTATSVTLTW----DSGNSEPVTYYGIQYRA--AGTEGPFQEVDGVATTRYS 375
Query: 1263 LTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI-W 1321
+ GL + Y +VLA IG G PS + RT + P P + + + S L+ W
Sbjct: 376 IGGLSPFSEYAFRVLAVNSIGRGPPSEA-VRARTGEQAPSSPPRRVQARMLSASTMLVQW 434
Query: 1322 QPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRK 1381
+PP PNG++ Y++ + ++ A + + T L P Y R+ A T
Sbjct: 435 EPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 1382 GWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRE 1441
G G + + V T++ QP + D R + LSW L P + I
Sbjct: 495 GDGPPSPTIQVKTQQGVPAQPADFQAEVESDTR---IQLSW------LLPPQERIIMYEL 545
Query: 1442 LPSGRWALHSASVSHNA-----SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTT 1496
+ WA H SS+ ++ LKP T Y+F++ A +D+G F+ E+ T
Sbjct: 546 V---YWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTA 602
Query: 1497 LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRG 1556
Q+ P P + +T+V + W PP D NG++ + + Y + E + G
Sbjct: 603 -QSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG 661
Query: 1557 INNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEV 1616
I+ ++W +L L K Y + + + VG GP S P V
Sbjct: 662 ISREHSSW--------------------DLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701
Query: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL--TER 1674
E VP+ PR V V +T + V W+ P Q+G I+GY++ + + G
Sbjct: 702 RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPI 761
Query: 1675 VKTLFLAE-NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFS 1733
++ + LAE + LT T Y V+VAA+ GDG RS P T A P P+ +
Sbjct: 762 IQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMM--- 818
Query: 1734 ELTTTSVN---VSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD 1790
++TT++N + W P+ G L GYRL Y C + ++ T+D G V
Sbjct: 819 -ISTTAMNTALLQWHPPKELPGELLGYRLQY--CRADE--ARPNTIDF-GKDDQHFTVTG 872
Query: 1791 LAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDP 1849
L +G TY FR+ AK G E E + T + P + + +S + W DP
Sbjct: 873 LHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAW---DP 929
Query: 1850 -----GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVN 1904
G I Y + R + +++ + F++ LKP +YD +V A
Sbjct: 930 PVLAERNGRIISYTVVFRDINSQ------QELQNITTDTRFTLTGLKPDTTYDIKVRAWT 983
Query: 1905 DYGFG--TPSSPSQSVPAQK 1922
G G +PS S+++P ++
Sbjct: 984 SKGSGPLSPSIQSRTMPVEQ 1003
Score = 197 bits (502), Expect = 7e-50
Identities = 264/1045 (25%), Positives = 424/1045 (40%), Gaps = 96/1045 (9%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAP-----DAGRYYVQAVNDKNGDNKT 195
P+P++TW + G+K+ I ++ + + P D Y A N G+ T
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSL-GEINT 118
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDG 255
S +++ E P P+I + P+ VV T+ C A P I W KD
Sbjct: 119 SAKLSVLEEE---QLPPGFPSIDMGPQ-LKVVEKARTATMLCAAGGNP--DPEISWFKDF 172
Query: 256 VLLSGGISD------HNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQ 309
+ + S+ + L I + SD G YEC A + + S Y+ V
Sbjct: 173 LPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAP 232
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQI 367
P V++ C A G P P + W A E+LT+ + G L++
Sbjct: 233 RFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGA-----EELTKEDEMPVGRNVLEL 287
Query: 368 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID--GMSVVLACET 425
S +V + + C A ++ G ++ + + V + + + P+D V + SV L +
Sbjct: 288 SNVV--RSANYTCVAISSLGMIEATAQVTVKA----LPKPPIDLVVTETTATSVTLTWD- 340
Query: 426 SGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG-------TYTCLAT 478
SG P + G + A+G+ F ++ ++ T S G + LA
Sbjct: 341 SGNSEPVTYY--GIQYRAAGTE--GPFQEVDG----VATTRYSIGGLSPFSEYAFRVLAV 392
Query: 479 NSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL 538
NS G S V ART P S + QA M+ T V E +G
Sbjct: 393 NSIGRGPPSE--AVRARTGEQAP---SSPPRRVQARMLSAST--MLVQWEPPEEPNGLVR 445
Query: 539 GTESH--PRIRLDRNGSLHISQTWSG---DIG------TYTCRVI--SAGGNDSRSAHLR 585
G + P R N + H T +G +G TY+ RV+ +A G+ S ++
Sbjct: 446 GYRVYYTPDSRRPPN-AWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 586 VRQLPHAPEHPVATLSTVER-RAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVD 644
V+ P P + VE I L+W P + + +E+ + + D
Sbjct: 505 VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKV--TFD 562
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTN 704
P +S T++ L P Y+F+L A +D+G G F+ E + P+APPQ V+ +
Sbjct: 563 P-TSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIE-ARTAQSTPSAPPQKVMCVSMGS 620
Query: 705 QSIMIQWQPPPESHQNGILKGYIIRY-CLAGLPVGYQFKNITDADVNNLLLEDLIIWTNY 763
++ + W PPP +NG++ Y + Y + G G + + ++ L L WT Y
Sbjct: 621 TTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEY 680
Query: 764 EIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGI 823
+ V A+ G G SS V T + VP+ PP V E NST + W P P +G
Sbjct: 681 RVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ 740
Query: 824 NQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRS 883
+GY++ E E + + +SGL T Y +V +TT GDG RS
Sbjct: 741 IRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARS 800
Query: 884 TPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVT 943
P++V T VPG + + ++T+L + W P E G L GYR+ + +
Sbjct: 801 KPKIVTTTGAVPGRPTMMISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRADEARPNTI 859
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELP-GPPTNLGIS 1002
+ + + VTGL TTY +AA G G+ I + P +LP G P NL ++
Sbjct: 860 DFGKD-DQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRT--PEDLPSGFPQNLHVT 916
Query: 1003 NIGPRSVTLQFRPGYDGKTS---ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVP 1059
+ + L + P + + IS +V + E L N +
Sbjct: 917 GLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQE---------LQNITTDTRFTLT 967
Query: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMP 1119
L P T Y ++R G+ P S PS + +T+ A N + A +TS+ L W
Sbjct: 968 GLKPDTTYDIKVRAWTSKGSGPLS-PSIQSRTMPVEQVFA-KNFRVAAAMKTSVLLSW-E 1024
Query: 1120 LPEMEYNGNPESVGYKIKYSRSDGH 1144
+P+ + P + Y + DGH
Sbjct: 1025 VPDSYKSAVPFKILYNGQSVEVDGH 1049
Score = 187 bits (474), Expect = 1e-46
Identities = 207/827 (25%), Positives = 345/827 (41%), Gaps = 97/827 (11%)
Query: 992 LPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
LP PP +L ++ SVTL + G + A G G +E +
Sbjct: 318 LPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA-AGTEGPFQE-------VDGV 369
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1111
+ L+PF+ Y+FR+ VN +G PPS+ R +T + P P V R S +
Sbjct: 370 ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRA-RTGEQAPSSPPRRVQARMLSAS 428
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEY 1171
++ ++W P PE E NG GY++ Y+ H T+ L Y
Sbjct: 429 TMLVQWEP-PE-EPNGLVR--GYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITY 484
Query: 1172 RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGL 1231
++V AF A+G GP S T+ +T++ VP+ P + A + + + + W +P +R
Sbjct: 485 SLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ-PADFQAEVESDTRIQLSWL-LPPQER--- 539
Query: 1232 VLGYKVMY-KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP 1290
++ Y+++Y +D D Q + V + + S L L LY Q+ A + +G G + P
Sbjct: 540 IIMYELVYWAAEDEDQQHK---VTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFT-P 595
Query: 1291 PILERTLDDVPG-PPMGILFPEVRTTSVRLIWQPPAAP--NGIILAYQITHR-LNTTTAN 1346
I RT P PP ++ + +T+VR+ W PP A NG+I Y + + ++
Sbjct: 596 TIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRG 655
Query: 1347 TATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRP 1406
V+ ++ + GL+ + Y + A T G G + ++V T++ D P P R
Sbjct: 656 RHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDE-DVPSGPPRK 714
Query: 1407 MVQQEDVRARSVLLSW-------EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
V+ E + + +V + W + G V Y ++ E P G + ++ A
Sbjct: 715 -VEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGE-PRGLPIIQDVMLAE-AQ 771
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
+ L P T+Y V A GD S+ + +TT A P ++S T T L
Sbjct: 772 ETTISGLTPETTYSVTVAAYTTKGDGARSKP-KIVTTTGAVPGRPTMMISTTAMNTA--L 828
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
++W PP E + G LLG+R++Y + +RP
Sbjct: 829 LQWHPPKE--LPGELLGYRLQY------------------------------CRADEARP 856
Query: 1580 SLTQYELDN-------LNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVV 1632
+ + D+ L+K Y R++ N G G +E+ E +P+ P+N+ V
Sbjct: 857 NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE-KEIRTPEDLPSGFPQNLHV 915
Query: 1633 HGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTG 1692
G T + ++ W+PP L +NG I Y + F + + + T + L L
Sbjct: 916 TGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT----DTRFTLTGLKP 971
Query: 1693 YTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
T Y + V A+ + G GP S Q +T + + + TSV +SWE P
Sbjct: 972 DTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPD---- 1027
Query: 1753 ILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1799
Y+ P + +V+V G+S L + DL Y F
Sbjct: 1028 -------SYKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEYSF 1066
Score = 52.0 bits (123), Expect = 6e-06
Identities = 61/221 (27%), Positives = 85/221 (38%), Gaps = 32/221 (14%)
Query: 1719 TQQAAPSAPSSVKFSELTTTSVNVSWEA----PQFPNGILEGYRLVYEPCSPVDGVSKIV 1774
T +A P P + +E T TSV ++W++ P GI P VDGV+
Sbjct: 314 TVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVA-TT 372
Query: 1775 TVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIEANVTTGPGEGAPGPPGVPII 1833
+ G SP Y FR+ A + GP EA V GE AP P +
Sbjct: 373 RYSIGGLSPF----------SEYAFRVLAVNSIGRGPPSEA-VRARTGEQAPSSPPRRVQ 421
Query: 1834 VRYSSA--IAIHWSSGDPGKGPITRYVIEARPSDE---GLWDILIKDIPKEVSSYTFSMD 1888
R SA + + W + G + Y + P W D + ++
Sbjct: 422 ARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTD-----AGLLTTVG 476
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPS-----SPSQSVPAQKAN 1924
L PG++Y RV+A G G PS Q VPAQ A+
Sbjct: 477 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPAD 517
Score = 38.9 bits (89), Expect = 0.056
Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 14/116 (12%)
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSGDPGKGPITRYVIEARPSD-EG 1867
E A VT + P PP + ++V ++A + + W SG+ P+T Y I+ R + EG
Sbjct: 308 EATAQVTV---KALPKPP-IDLVVTETTATSVTLTWDSGN--SEPVTYYGIQYRAAGTEG 361
Query: 1868 LWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKA 1923
+ + V++ +S+ L P Y FRV+AVN G G PS ++ ++A
Sbjct: 362 PFQEV-----DGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQA 412
>gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo
sapiens]
Length = 1304
Score = 264 bits (674), Expect = 8e-70
Identities = 257/1067 (24%), Positives = 439/1067 (41%), Gaps = 90/1067 (8%)
Query: 44 LVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLD---------------RTHAGF 88
+V+ C A+G P F W N T F ++ ++T T+ G
Sbjct: 64 IVIQCEAKGKPPPSFSWTRNG---THFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
Query: 89 YRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVS--HGEAAVIRAPRIASFPQPQVT 146
Y+C RN GA + V+ + + + EK + ++ G++ V+ P P +
Sbjct: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTK-EKLEPITLQSGQSLVLPCRPPIGLPPPIIF 179
Query: 147 WFRDG-RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDN-KTSQPITLTVE 204
W + +++P S R++ L L + + D Y+ + + QPI++ V
Sbjct: 180 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 239
Query: 205 NVGGPADPIA------------------PTIIIPPKNTSVVAGT--SEVTLECVANARPL 244
+V D IA PT + P N S + ++LEC+A P
Sbjct: 240 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 299
Query: 245 IKLHIIW-KKDGVLLSGGISDHN--RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 301
++ W K+DG+L N + L I + + +D+G Y+C A +++ ++
Sbjct: 300 PIIY--WAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA---KNALGAIHHTIS 354
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
+ V P ++ P+ + + E I C+A G P P I+W + +E+ R+ +
Sbjct: 355 VRVKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKID 413
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNI-TRGPLDSTVIDGMSVV 420
+ S + + ++QC A N G + + ++ V + P I T VI +
Sbjct: 414 GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPAL 473
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
L C G+P P I W KG + ++ + E+G+L I GTYTC+A N
Sbjct: 474 LDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNK 530
Query: 481 RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
G+ + L + T I K P+ V +G+ S C V HD +++ +W KD L +
Sbjct: 531 LGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPS 590
Query: 541 ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE------ 594
+ R +D++ L ++ D GTYTC + + S SA L V P
Sbjct: 591 DE--RFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVP 647
Query: 595 HPVATLSTVER--RAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTV 652
+P L ++ +++ L+WT D NSP+ ++I+E + + + T T
Sbjct: 648 NPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTA 707
Query: 653 K-GLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQW 711
+ L P +Y FR+ AVN +GK S+ +E+ P P V G +++I W
Sbjct: 708 QLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITW 767
Query: 712 QPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYN 771
+P NG G + ++ ++ A+V+ ++ + Y I+V A N
Sbjct: 768 KPLNGFESNG--PGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALN 825
Query: 772 SAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIA 831
G + V + + +P V PGNV NST W+ + I G QGY++
Sbjct: 826 DMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY 885
Query: 832 WEPEQEEEVTMVTARPN---FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLV 888
W+ + + FQ S G + GL+ F+ Y +V G+GP S ++
Sbjct: 886 WKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVF 945
Query: 889 RTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTN---TRVTHY 945
T E VP L SL + W P NGILT Y + ++ N T+ V
Sbjct: 946 NTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLK 1005
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG-QVSASTISSGVPPELPGPPTNLG-ISN 1003
+P + + L T Y A TS G G Q++ +++ + P G +
Sbjct: 1006 IPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQA 1065
Query: 1004 IGPRSVTLQFRPG---------YDGKTSISRWLVEAQVGVVGEGEEW 1041
+ PR L Y+G ++ ++ + GV G EEW
Sbjct: 1066 VNPRISNLTAAAAETYANISWEYEGPEHVNFYV---EYGVAGSKEEW 1109
Score = 203 bits (516), Expect = 2e-51
Identities = 166/591 (28%), Positives = 259/591 (43%), Gaps = 59/591 (9%)
Query: 1398 DRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTREL--PSGRWALHSASVS 1455
D P PP ++ D +SV LSW PG D SP+ + I+ + G W H VS
Sbjct: 645 DVPNPPFD--LELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH-HQTEVS 701
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTT 1515
++ + +L P+ +Y FRV A N IG S SE SE T + PD+ PT +
Sbjct: 702 GTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 760
Query: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
+++I W+P + NG L +++ +R+ + W + + N
Sbjct: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQ--------------KDGDDEWTSVV----VAN 802
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGA 1635
+S+ Y + Y I++ N +G P GE +P AP NV V+
Sbjct: 803 VSK-----YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 857
Query: 1636 TATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQ------RGNLTERVKTLFLAENSVKLKN 1689
+T +V W+P PL S G +QGY+IY+W+ Q R ++ +++ T ++ L
Sbjct: 858 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 917
Query: 1690 LTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQF 1749
L ++ Y ++V N G+GP S T + PSAPSS+K T S+ + W+ P
Sbjct: 918 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSH 977
Query: 1750 PNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT-Y 1808
PNGIL Y L Y+P + + +V + + N W +K+L Y+F A+T
Sbjct: 978 PNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW-TLKNLNFSTRYKFYFYAQTSAGS 1036
Query: 1809 GPEIEANVTTGPGEGAPGPPGV---------PIIVRYSSAIA-----IHWSSGDPGKGPI 1854
G +I T E PP V P I ++A A I W P +
Sbjct: 1037 GSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEH--V 1094
Query: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSP 1914
YV + W K+I S+ F + L PG +Y RV AV D GF +
Sbjct: 1095 NFYVEYGVAGSKEEWR---KEIVNGSRSF-FGLKGLMPGTAYKVRVGAVGDSGFVSSEDV 1150
Query: 1915 SQSVPAQKAN--PFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKK 1963
++ PA + + WF+ ++ V L+ ++LL+ I R + KY K
Sbjct: 1151 FETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVK 1201
Score = 166 bits (420), Expect = 2e-40
Identities = 147/545 (26%), Positives = 232/545 (42%), Gaps = 43/545 (7%)
Query: 979 VSASTISSGVPP--------ELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEA 1030
VSAS + S V P ++P PP +L +++ +SV L + PG D + I+++++E
Sbjct: 625 VSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEY 684
Query: 1031 QVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQ 1090
+ + G L H + ++ L+P+ YSFR+ VN +G S PS+ S +
Sbjct: 685 EDAMHKPG----LWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYL 740
Query: 1091 TLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSH 1150
T + PD P V + +L + W PL E NG + YK+ + + DG + S
Sbjct: 741 TKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG--PGLQYKVSWRQKDGDDEWTSV 798
Query: 1151 VVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALA 1210
VV + + Y + + Y ++VQA N +G P V+G + E +P P NV
Sbjct: 799 VVANVSK--YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV 856
Query: 1211 TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE------GNSSRSAQLT 1264
S+ V W VP G + GY++ Y + S ++ +E S L
Sbjct: 857 VNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLP 916
Query: 1265 GLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
GL + Y + V G+G P+ P + T + VP P + S+ L W PP
Sbjct: 917 GLEPFSHYTLNVRVVNGKGEG-PASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPP 975
Query: 1325 AAPNGIILAYQITHR-LNTTTANTATVEVLAPSAR-QYTATGLKPESVYLFRITAQTRKG 1382
+ PNGI+ Y + ++ +N+T V++ P+ + ++T L + Y F AQT G
Sbjct: 976 SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAG 1035
Query: 1383 WGEAAEALVVTTEKRDRPQPPS---------RPMVQQEDVRARSVL--LSWEPGSDGLSP 1431
G VTT PP P + A +SWE +G
Sbjct: 1036 SGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWE--YEGPEH 1093
Query: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491
V +Y W V+ + S F + L P T+YK RV A +GDS F
Sbjct: 1094 VNFYVEYGVAGSKEEW--RKEIVNGSRSFFGLKGLMPGTAYKVRVGA---VGDSGFVSSE 1148
Query: 1492 ESLTT 1496
+ T
Sbjct: 1149 DVFET 1153
Score = 79.7 bits (195), Expect = 3e-14
Identities = 101/386 (26%), Positives = 151/386 (39%), Gaps = 40/386 (10%)
Query: 39 LEGNRLVLTCMAEG------SWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCI 92
L GN L L C+AEG W E L NR + K + E I + +G Y+CI
Sbjct: 283 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK-NFEKTLQIIHVSEADSGNYQCI 341
Query: 93 VRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGR 152
+N +GA + V+V + ++ +S GE + R P+P+++W +G
Sbjct: 342 AKNALGA-IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC-RANGNPKPRISWLTNGV 399
Query: 153 KI-----PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVG 207
I PS +I + +I S V + AV N N+ + NV
Sbjct: 400 PIEIAPDDPSRKI----DGDTIIFSNVQERS-----SAVYQCNASNEYGYLLANAFVNV- 449
Query: 208 GPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGI--SDH 265
A+P P I+ P V L+C PL + G L I
Sbjct: 450 -LAEP--PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE 506
Query: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
N L IP G Y C A + + V +L + +P VK+PE + + +
Sbjct: 507 NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV---HLEIKDPTWIVKQPE-YAVVQRGSM 562
Query: 326 VDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFAR 383
V C+ K S+T W KD E+ RF D L ++ + DD+G + C A
Sbjct: 563 VSFECKVKHDHTLSLTVLWLKDNR--ELPSDERFTVDKD-HLVVADVSDDDSGTYTCVAN 619
Query: 384 NAAGEVQTSTYLAVTSIAPNITRGPL 409
V S L+V +AP T P+
Sbjct: 620 TTLDSVSASAVLSV--VAPTPTPAPV 643
Score = 61.6 bits (148), Expect = 8e-09
Identities = 41/140 (29%), Positives = 70/140 (50%), Gaps = 9/140 (6%)
Query: 304 VLEPPQFVKE-PERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND 362
+++PP ++ P+ +I E +V I C+AKG PPPS +W ++ +++K +
Sbjct: 42 LVQPPTITQQSPKDYIIDPRENIV-IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 100
Query: 363 GGLQISGLVPDD-----TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDG 416
G I ++ + G++QC ARN G ++ + S +P T+ L+ T+ G
Sbjct: 101 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSG 160
Query: 417 MSVVLACETS-GAPRPAITW 435
S+VL C G P P I W
Sbjct: 161 QSLVLPCRPPIGLPPPIIFW 180
Score = 35.4 bits (80), Expect = 0.61
Identities = 37/167 (22%), Positives = 65/167 (38%), Gaps = 6/167 (3%)
Query: 402 PNITR-GPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 460
P IT+ P D + ++V+ CE G P P+ +W + L P +G+L
Sbjct: 46 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKP-GTGTL 104
Query: 461 LISPTHISDA----GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMV 516
+I+ A G Y C A N RG ++ +V +R+ + + + + + S+V
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLV 164
Query: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
+ I+ D + R+ NG L+ S D
Sbjct: 165 LPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 211
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 264 bits (674), Expect = 8e-70
Identities = 244/994 (24%), Positives = 417/994 (41%), Gaps = 71/994 (7%)
Query: 44 LVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLD---------------RTHAGF 88
+V+ C A+G P F W N T F ++ ++T T+ G
Sbjct: 58 IVIQCEAKGKPPPSFSWTRNG---THFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114
Query: 89 YRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVS--HGEAAVIRAPRIASFPQPQVT 146
Y+C RN GA + V+ + + + EK + ++ G++ V+ P P +
Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTK-EKLEPITLQSGQSLVLPCRPPIGLPPPIIF 173
Query: 147 WFRDG-RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDN-KTSQPITLTVE 204
W + +++P S R++ L L + + D Y+ + + QPI++ V
Sbjct: 174 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 233
Query: 205 NVGGPADPIA------------------PTIIIPPKNTSVVAGT--SEVTLECVANARPL 244
+V D IA PT + P N S + ++LEC+A P
Sbjct: 234 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 293
Query: 245 IKLHIIW-KKDGVLLSGGISDHN--RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 301
++ W K+DG+L N + L I + + +D+G Y+C A +++ ++
Sbjct: 294 PIIY--WAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA---KNALGAIHHTIS 348
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
+ V P ++ P+ + + E I C+A G P P I+W + +E+ R+ +
Sbjct: 349 VRVKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKID 407
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNI-TRGPLDSTVIDGMSVV 420
+ S + + ++QC A N G + + ++ V + P I T VI +
Sbjct: 408 GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPAL 467
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
L C G+P P I W KG + ++ + E+G+L I GTYTC+A N
Sbjct: 468 LDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNK 524
Query: 481 RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
G+ + L + T I K P+ V +G+ S C V HD +++ +W KD L +
Sbjct: 525 LGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPS 584
Query: 541 ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
+ R +D++ L ++ D GTYTC + + S SA L V +P+ P L
Sbjct: 585 DE--RFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFD--LEL 639
Query: 601 STVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVK-GLVPAR 659
+ +++ L+WT D NSP+ ++I+E + + + T T + L P
Sbjct: 640 TDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYV 699
Query: 660 SYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
+Y FR+ AVN +GK S+ +E+ P P V G +++I W+P
Sbjct: 700 NYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 759
Query: 720 NGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYS 779
NG G + ++ ++ A+V+ ++ + Y I+V A N G
Sbjct: 760 NG--PGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEP 817
Query: 780 SKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEE 839
+ V + + +P V PGNV NST W+ + I G QGY++ W+ + +
Sbjct: 818 AVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSK 877
Query: 840 VTMVTARPN---FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG 896
FQ S G + GL+ F+ Y +V G+GP S ++ T E VP
Sbjct: 878 RNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS 937
Query: 897 PVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTN---TRVTHYLPNVTLEY 953
L SL + W P NGILT Y + ++ N T+ V +P +
Sbjct: 938 APSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW 997
Query: 954 RVTGLTALTTYTIEVAAMTSKGQG-QVSASTISS 986
+ L T Y A TS G G Q++ +++
Sbjct: 998 TLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1031
Score = 173 bits (438), Expect = 2e-42
Identities = 121/416 (29%), Positives = 192/416 (46%), Gaps = 36/416 (8%)
Query: 1398 DRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTREL--PSGRWALHSASVS 1455
D P PP ++ D +SV LSW PG D SP+ + I+ + G W H VS
Sbjct: 629 DVPNPPFD--LELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH-HQTEVS 685
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTT 1515
++ + +L P+ +Y FRV A N IG S SE SE T + PD+ PT +
Sbjct: 686 GTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 744
Query: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
+++I W+P + NG L +++ +R+ + W + + N
Sbjct: 745 DNLVITWKPLNGFESNGPGLQYKVSWRQ--------------KDGDDEWTSVV----VAN 786
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGA 1635
+S+ Y + Y I++ N +G P GE +P AP NV V+
Sbjct: 787 VSK-----YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 841
Query: 1636 TATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQ------RGNLTERVKTLFLAENSVKLKN 1689
+T +V W+P PL S G +QGY+IY+W+ Q R ++ +++ T ++ L
Sbjct: 842 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 901
Query: 1690 LTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQF 1749
L ++ Y ++V N G+GP S T + PSAPSS+K T S+ + W+ P
Sbjct: 902 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSH 961
Query: 1750 PNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1805
PNGIL Y L Y+P + + +V + + N W +K+L Y+F A+T
Sbjct: 962 PNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW-TLKNLNFSTRYKFYFYAQT 1016
Score = 155 bits (392), Expect = 4e-37
Identities = 119/424 (28%), Positives = 194/424 (45%), Gaps = 19/424 (4%)
Query: 979 VSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEG 1038
VSAS + S V ++P PP +L +++ +SV L + PG D + I+++++E + + G
Sbjct: 619 VSASAVLSVV--DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPG 676
Query: 1039 EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDM 1098
L H + ++ L+P+ YSFR+ VN +G S PS+ S + T + PD
Sbjct: 677 ----LWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDK 732
Query: 1099 APANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER 1158
P V + +L + W PL E NG + YK+ + + DG + S VV + +
Sbjct: 733 NPTAVEGLGSEPDNLVITWKPLNGFESNG--PGLQYKVSWRQKDGDDEWTSVVVANVSK- 789
Query: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLV 1218
Y + + Y ++VQA N +G P V+G + E +P P NV S+ V
Sbjct: 790 -YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 848
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE------GNSSRSAQLTGLGKYVLY 1272
W VP G + GY++ Y + S ++ +E S L GL + Y
Sbjct: 849 HWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHY 908
Query: 1273 EVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIIL 1332
+ V G+G P+ P + T + VP P + S+ L W PP+ PNGI+
Sbjct: 909 TLNVRVVNGKGEG-PASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILT 967
Query: 1333 AYQITHR-LNTTTANTATVEVLAPSAR-QYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
Y + ++ +N+T V++ P+ + ++T L + Y F AQT G G
Sbjct: 968 EYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEE 1027
Query: 1391 VVTT 1394
VTT
Sbjct: 1028 AVTT 1031
Score = 79.3 bits (194), Expect = 4e-14
Identities = 101/484 (20%), Positives = 177/484 (36%), Gaps = 62/484 (12%)
Query: 1505 PTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATW 1564
P L +T SV + W P D N + F I Y + +++ PG W
Sbjct: 634 PFDLELTDQLDKSVQLSWTPG--DDNNSPITKFIIEYEDAMHK------------PGL-W 678
Query: 1565 AELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAVP 1623
T + + ++ L+ Y Y R+ N++G+ PS ++ + P
Sbjct: 679 HHQTEVSGTQTTAQLKLSPYV--------NYSFRVMAVNSIGKSLPSEASEQYLTKASEP 730
Query: 1624 TAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAEN 1683
P V G+ L +TW+P NG YK+ W + G+ E + +
Sbjct: 731 DKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVS-WRQKDGD-DEWTSVVVANVS 788
Query: 1684 SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPS-APSSVKFSELTTTSVNV 1742
+ + Y++ V A N G P G + + P AP +V+ + + +T V
Sbjct: 789 KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 848
Query: 1743 SWEAPQFPN--GILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFR 1800
W+ + G L+GYR+ Y K + + + K+ T+
Sbjct: 849 HWDPVPLKSIRGHLQGYRIYYW---------KTQSSSKRNRRHIEKKILTFQGSKTHGML 899
Query: 1801 IRAKTFTYGPEIEANVTTGPGEGAPGPP-------GVP-------IIVRYSSAIAIHWSS 1846
+ F++ + V G GEG P GVP I+ ++ + W
Sbjct: 900 PGLEPFSHYT-LNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 958
Query: 1847 GDPGKGPITRYVIEARP--SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVN 1904
G +T Y ++ +P S L ++ IP + +T L Y F A
Sbjct: 959 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKN--LNFSTRYKFYFYAQT 1016
Query: 1905 DYGFGTPSSPSQSVPAQKANPFYE-----EWWFLVVIALVGLIFILLLVFVLIIRGQSKK 1959
G G+ + +A + + WF+ ++ V L+ ++LL+ I R + K
Sbjct: 1017 SAGSGSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGK 1076
Query: 1960 YAKK 1963
Y K
Sbjct: 1077 YPVK 1080
Score = 77.8 bits (190), Expect = 1e-13
Identities = 99/380 (26%), Positives = 148/380 (38%), Gaps = 39/380 (10%)
Query: 39 LEGNRLVLTCMAEG------SWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCI 92
L GN L L C+AEG W E L NR + K + E I + +G Y+CI
Sbjct: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK-NFEKTLQIIHVSEADSGNYQCI 335
Query: 93 VRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGR 152
+N +GA + V+V + ++ +S GE + R P+P+++W +G
Sbjct: 336 AKNALGA-IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC-RANGNPKPRISWLTNGV 393
Query: 153 KI-----PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVG 207
I PS +I + +I S V + AV N N+ + NV
Sbjct: 394 PIEIAPDDPSRKI----DGDTIIFSNVQERS-----SAVYQCNASNEYGYLLANAFVNV- 443
Query: 208 GPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGI--SDH 265
A+P P I+ P V L+C PL + G L I
Sbjct: 444 -LAEP--PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE 500
Query: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
N L IP G Y C A + + V +L + +P VK+PE + + +
Sbjct: 501 NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV---HLEIKDPTWIVKQPE-YAVVQRGSM 556
Query: 326 VDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFAR 383
V C+ K S+T W KD E+ RF D L ++ + DD+G + C A
Sbjct: 557 VSFECKVKHDHTLSLTVLWLKDNR--ELPSDERFTVDKD-HLVVADVSDDDSGTYTCVAN 613
Query: 384 NAAGEVQTSTYLAVTSIAPN 403
V S L+V + PN
Sbjct: 614 TTLDSVSASAVLSVVDV-PN 632
Score = 63.2 bits (152), Expect = 3e-09
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 9/142 (6%)
Query: 302 LSVLEPPQFVKE-PERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
L +++PP ++ P+ +I E +V I C+AKG PPPS +W ++ +++K +
Sbjct: 34 LDLVQPPTITQQSPKDYIIDPRENIV-IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK 92
Query: 361 NDGGLQISGLVPDD-----TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVI 414
G I ++ + G++QC ARN G ++ + S +P T+ L+ T+
Sbjct: 93 PGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQ 152
Query: 415 DGMSVVLACETS-GAPRPAITW 435
G S+VL C G P P I W
Sbjct: 153 SGQSLVLPCRPPIGLPPPIIFW 174
Score = 56.2 bits (134), Expect = 3e-07
Identities = 90/411 (21%), Positives = 153/411 (37%), Gaps = 56/411 (13%)
Query: 1218 VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW--LVEGNSSRSAQLTGLGKYVLYEVQ 1275
V+ S P D N + + + Y+ D+ +P W E + +++ L YV Y +
Sbjct: 647 VQLSWTPGDDNNSPITKFIIEYE--DAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 704
Query: 1276 VLAFTRIGDGSPSHPPILERTLDDVPGP-PMGILFPEVRTTSVRLIWQPPAA--PNGIIL 1332
V+A IG PS T P P + ++ + W+P NG L
Sbjct: 705 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 764
Query: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
Y+++ R + V+ + +Y +G YL ++ A G+ A E VV
Sbjct: 765 QYKVSWRQKD--GDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGF--APEPAVV 820
Query: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVL-----LSWEPGSDGLSPVR--------YYTIQT 1439
+ PMV +VR V + W+P L +R YY
Sbjct: 821 MGHSGE-----DLPMVAPGNVRVNVVNSTLAEVHWDPVP--LKSIRGHLQGYRIYYWKTQ 873
Query: 1440 RELPSGRWALHSASVSHNASSF--IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTL 1497
R + ++ S ++ L+PF+ Y V+ N G+ S + T
Sbjct: 874 SSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPD-RVFNTP 932
Query: 1498 QAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
+ P AP+ L + T S+ + W PP+ NGIL + ++Y+
Sbjct: 933 EGVPS-APSSLKIVNPTLDSLTLEWDPPSHP--NGILTEYTLKYQ--------------- 974
Query: 1558 NNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG 1608
P + EL + ++ + T++ L NLN RY+ + G G
Sbjct: 975 --PINSTHELGPLVDLKIPANK--TRWTLKNLNFSTRYKFYFYAQTSAGSG 1021
Score = 49.3 bits (116), Expect = 4e-05
Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 9/105 (8%)
Query: 1825 PGPP-GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPS--DEGLWDILIKDIPKEVS 1881
P PP + + + ++ + W+ GD PIT+++IE + GLW EVS
Sbjct: 631 PNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHH-----QTEVS 685
Query: 1882 SYTFSMDI-LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
+ + L P V+Y FRV+AVN G PS S+ + + P
Sbjct: 686 GTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEP 730
Score = 35.4 bits (80), Expect = 0.61
Identities = 37/167 (22%), Positives = 65/167 (38%), Gaps = 6/167 (3%)
Query: 402 PNITR-GPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 460
P IT+ P D + ++V+ CE G P P+ +W + L P +G+L
Sbjct: 40 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKP-GTGTL 98
Query: 461 LISPTHISDA----GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMV 516
+I+ A G Y C A N RG ++ +V +R+ + + + + + S+V
Sbjct: 99 IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLV 158
Query: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
+ I+ D + R+ NG L+ S D
Sbjct: 159 LPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 205
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 260 bits (665), Expect = 9e-69
Identities = 290/1118 (25%), Positives = 466/1118 (41%), Gaps = 128/1118 (11%)
Query: 198 PITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVL 257
P + + V G P I P++ + ++G + C A P K I W K G
Sbjct: 16 PALVMLGLVAGAHGDSKPVFIKVPEDQTGLSG-GVASFVCQATGEP--KPRITWMKKGKK 72
Query: 258 LSGGISDHNRRLTIPNPTGS-----------DAGYYECEAVLRSSSVPSVVRGAYLSVLE 306
+S S + + GS D YEC A ++S+ + A LSVLE
Sbjct: 73 VS---SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTA---TNSLGEINTSAKLSVLE 126
Query: 307 ----PPQFVK---EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLT-RFR 358
PP F P+ + E + + C A G P P I+W+KD V+ R +
Sbjct: 127 EEQLPPGFPSIDMGPQLKVV-EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK 185
Query: 359 QRNDGGLQISGLVPDDTGMFQCFARNAAG---EVQTSTYLAVTSIAPNITRGPLDSTVID 415
Q G LQI D G ++C A N+AG + Y+ V +AP + P V+
Sbjct: 186 QLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP 245
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
G SV L C GAP P + W G +L + + G ++ +++ + YTC
Sbjct: 246 GGSVNLTCVAVGAPMPYVKWMMGAE-------ELTKEDEMPVGRNVLELSNVVRSANYTC 298
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 535
+A +S G+ EA+A + V A + KPP D V + T S+ + Y +
Sbjct: 299 VAISSLGMIEATAQVTVKA---LPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYR 355
Query: 536 ATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG--GNDSRSAHLRVRQLPHAP 593
A GTE P +D + S Y RV++ G S +R R AP
Sbjct: 356 AA-GTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAP 413
Query: 594 EHPVATLST--VERRAINLTWTKPFDGNSPLIRY-ILEMSENNAPWTVLLASVDPKATSV 650
P + + + + W P + N + Y + ++ P
Sbjct: 414 SSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLT 473
Query: 651 TVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQ 710
TV L+P +Y R+ A VG G S T +V + P A P + A ++ I +
Sbjct: 474 TVGSLLPGITYSLRVLAFTAVGDGPPSP-TIQVKTQQGVP-AQPADFQAEVESDTRIQLS 531
Query: 711 WQPPPESHQNGILKGYIIRYCL---AGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEV 767
W PP+ II Y L A Q K +T ++ LEDL T Y ++
Sbjct: 532 WLLPPQER--------IIMYELVYWAAEDEDQQHK-VTFDPTSSYTLEDLKPDTLYRFQL 582
Query: 768 AAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGI---- 823
AA + G+GV++ + T Q P+ PP V + STT+R +W P NG+
Sbjct: 583 AARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQY 642
Query: 824 NQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRS 883
+ Y+ + E V ++ + D + GL+K+TEY V T G GP S
Sbjct: 643 SVAYEAVDGEDRGRHVVDGISREHSSWDLV------GLEKWTEYRVWVRAHTDVGPGPES 696
Query: 884 TPQLVRTHEDVP-GPVGHLSFSEILDTSLKVSWQ--EPGEKNGILTGYRISWEEYNRTNT 940
+P LVRT EDVP GP + + T++ V W+ P +++G + GY++++
Sbjct: 697 SPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756
Query: 941 RVTHYLPNVTL-------------EYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSG 987
R + +V L E ++GLT TTY++ VAA T+KG G S I +
Sbjct: 757 RGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVT- 815
Query: 988 VPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLV------EAQVGVVGEGEEW 1041
+PG PT + IS + LQ+ P + + + + EA+ + G+
Sbjct: 816 TTGAVPGRPTMM-ISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGK-- 872
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPA 1101
D + V L+ T Y FR+ N G + ++I+T + P P
Sbjct: 873 ----------DDQHFTVTGLHKGTTYIFRLAAKNRAGLG--EEFEKEIRTPEDLPSGFPQ 920
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYT 1161
N+ + + ++ L W P E NG + Y + + R + L ++ D +T
Sbjct: 921 NLHVTGLTTSTTELAWDPPVLAERNG--RIISYTVVF-RDINSQQELQNITTD---TRFT 974
Query: 1162 IEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWS 1221
+ L+ T Y ++V+A+ + GSGP S ++ RT V N A +S+L+ W
Sbjct: 975 LTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTM-PVEQVFAKNFRVAAAMKTSVLLSW- 1032
Query: 1222 EVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
EVP++ ++ + +K++Y + + V+G+S R
Sbjct: 1033 EVPDSYKS--AVPFKILYNGQSVE-------VDGHSMR 1061
Score = 204 bits (520), Expect = 6e-52
Identities = 199/775 (25%), Positives = 326/775 (42%), Gaps = 70/775 (9%)
Query: 890 THEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNV 949
T + +P P L +E TS+ ++W + +T Y I + T
Sbjct: 314 TVKALPKPPIDLVVTETTATSVTLTWDSGNSEP--VTYYGIQYRAAG-TEGPFQEVDGVA 370
Query: 950 TLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV 1009
T Y + GL+ + Y V A+ S G+G S + + PP + + ++
Sbjct: 371 TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTM 430
Query: 1010 TLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSF 1069
+Q+ P + + + V W N V L P YS
Sbjct: 431 LVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW----HKHNTDAGLLTTVGSLLPGITYSL 486
Query: 1070 RMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNP 1129
R+ VG PPS P+ +++T Q P PA+ S+T + L W+ LP E
Sbjct: 487 RVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQLSWL-LPPQE----- 538
Query: 1130 ESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQT 1189
+ Y++ Y ++ + H V YT+EDL+ T YR Q+ A + +G G ++ T
Sbjct: 539 RIIMYELVYWAAEDEDQ--QHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT 596
Query: 1190 VVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPR 1249
+ RT +S PS+ P V ++ S+++ V W P RNG++ Y V Y+ D + + R
Sbjct: 597 IEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGR 656
Query: 1250 FWLVEGNSSR--SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMG 1306
+V+G S S L GL K+ Y V V A T +G G P P+L RT +DVP GPP
Sbjct: 657 H-VVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG-PESSPVLVRTDEDVPSGPPRK 714
Query: 1307 ILFPEVRTTSVRLIWQ--PPAAPNGIILAYQITH-RLNTTTANTATV--EVLAPSAR--- 1358
+ + +T+V + W+ P+ +G I YQ+T+ RL + +V+ A+
Sbjct: 715 VEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRP 774
Query: 1359 ------QYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQED 1412
+ T +GL PE+ Y + A T KG G ++ +VTT P RP +
Sbjct: 775 EESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTT----TGAVPGRPTMMIST 830
Query: 1413 VRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY 1472
+ LL W P + + Y +Q R ++ + F V L T+Y
Sbjct: 831 TAMNTALLQWHPPKELPGELLGYRLQYCRADEAR--PNTIDFGKDDQHFTVTGLHKGTTY 888
Query: 1473 KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKING 1532
FR+ A N G E E + + T + P P L VT TT++ + W PP + NG
Sbjct: 889 IFRLAAKNRAGLGE--EFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNG 946
Query: 1533 ILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKH 1592
++ + + +R ++ S ++N++ T++ L L
Sbjct: 947 RIISYTVVFR-----------------------DINSQQELQNITTD--TRFTLTGLKPD 981
Query: 1593 RRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPP 1647
Y+I++ + + G GP SP + V +N V A T + ++WE P
Sbjct: 982 TTYDIKVRAWTSKGSGPLSPSIQSRT-MPVEQVFAKNFRVAAAMKTSVLLSWEVP 1035
Score = 202 bits (513), Expect = 4e-51
Identities = 192/749 (25%), Positives = 316/749 (42%), Gaps = 87/749 (11%)
Query: 1203 PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQ 1262
P ++ TT++S+ + W ++ + V Y + Y+ + T+ F V+G ++
Sbjct: 322 PIDLVVTETTATSVTLTW----DSGNSEPVTYYGIQYRA--AGTEGPFQEVDGVATTRYS 375
Query: 1263 LTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI-W 1321
+ GL + Y +VLA IG G PS + RT + P P + + + S L+ W
Sbjct: 376 IGGLSPFSEYAFRVLAVNSIGRGPPSEA-VRARTGEQAPSSPPRRVQARMLSASTMLVQW 434
Query: 1322 QPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRK 1381
+PP PNG++ Y++ + ++ A + + T L P Y R+ A T
Sbjct: 435 EPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 1382 GWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRE 1441
G G + + V T++ QP + D R + LSW L P + I
Sbjct: 495 GDGPPSPTIQVKTQQGVPAQPADFQAEVESDTR---IQLSW------LLPPQERIIMYEL 545
Query: 1442 LPSGRWALHSASVSHNA-----SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTT 1496
+ WA H SS+ ++ LKP T Y+F++ A +D+G F+ E+ T
Sbjct: 546 V---YWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTA 602
Query: 1497 LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRG 1556
Q+ P P + +T+V + W PP D NG++ + + Y + E + G
Sbjct: 603 -QSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG 661
Query: 1557 INNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEV 1616
I+ ++W +L L K Y + + + VG GP S P V
Sbjct: 662 ISREHSSW--------------------DLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701
Query: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL--TER 1674
E VP+ PR V V +T + V W+ P Q+G I+GY++ + + G
Sbjct: 702 RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPI 761
Query: 1675 VKTLFLAE----------NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAP 1724
++ + LAE + LT T Y V+VAA+ GDG RS P T A P
Sbjct: 762 IQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVP 821
Query: 1725 SAPSSVKFSELTTTSVN---VSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGN 1781
P+ + ++TT++N + W P+ G L GYRL Y C + ++ T+D G
Sbjct: 822 GRPTMM----ISTTAMNTALLQWHPPKELPGELLGYRLQY--CRADE--ARPNTIDF-GK 872
Query: 1782 SPLWLKVKDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAI 1840
V L +G TY FR+ AK G E E + T + P + + +S
Sbjct: 873 DDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTT 932
Query: 1841 AIHWSSGDP-----GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVS 1895
+ W DP G I Y + R + +++ + F++ LKP +
Sbjct: 933 ELAW---DPPVLAERNGRIISYTVVFRDINSQ------QELQNITTDTRFTLTGLKPDTT 983
Query: 1896 YDFRVIAVNDYGFG--TPSSPSQSVPAQK 1922
YD +V A G G +PS S+++P ++
Sbjct: 984 YDIKVRAWTSKGSGPLSPSIQSRTMPVEQ 1012
Score = 196 bits (498), Expect = 2e-49
Identities = 268/1055 (25%), Positives = 429/1055 (40%), Gaps = 107/1055 (10%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAP-----DAGRYYVQAVNDKNGDNKT 195
P+P++TW + G+K+ I ++ + + P D Y A N G+ T
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSL-GEINT 118
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDG 255
S +++ E P P+I + P+ VV T+ C A P I W KD
Sbjct: 119 SAKLSVLEEE---QLPPGFPSIDMGPQ-LKVVEKARTATMLCAAGGNP--DPEISWFKDF 172
Query: 256 VLLSGGISD------HNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQ 309
+ + S+ + L I + SD G YEC A + + S Y+ V
Sbjct: 173 LPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAP 232
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQI 367
P V++ C A G P P + W A E+LT+ + G L++
Sbjct: 233 RFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGA-----EELTKEDEMPVGRNVLEL 287
Query: 368 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID--GMSVVLACET 425
S +V + + C A ++ G ++ + + V + + + P+D V + SV L +
Sbjct: 288 SNVV--RSANYTCVAISSLGMIEATAQVTVKA----LPKPPIDLVVTETTATSVTLTWD- 340
Query: 426 SGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG-------TYTCLAT 478
SG P + G + A+G+ F ++ ++ T S G + LA
Sbjct: 341 SGNSEPVTYY--GIQYRAAGTE--GPFQEVDG----VATTRYSIGGLSPFSEYAFRVLAV 392
Query: 479 NSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL 538
NS G S V ART P S + QA M+ T V E +G
Sbjct: 393 NSIGRGPPSE--AVRARTGEQAP---SSPPRRVQARMLSAST--MLVQWEPPEEPNGLVR 445
Query: 539 GTESH--PRIRLDRNGSLHISQTWSG---DIG------TYTCRVI--SAGGNDSRSAHLR 585
G + P R N + H T +G +G TY+ RV+ +A G+ S ++
Sbjct: 446 GYRVYYTPDSRRPPN-AWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 586 VRQLPHAPEHPVATLSTVER-RAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVD 644
V+ P P + VE I L+W P + + +E+ + + D
Sbjct: 505 VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKV--TFD 562
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTN 704
P +S T++ L P Y+F+L A +D+G G F+ E + P+APPQ V+ +
Sbjct: 563 P-TSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIE-ARTAQSTPSAPPQKVMCVSMGS 620
Query: 705 QSIMIQWQPPPESHQNGILKGYIIRY-CLAGLPVGYQFKNITDADVNNLLLEDLIIWTNY 763
++ + W PPP +NG++ Y + Y + G G + + ++ L L WT Y
Sbjct: 621 TTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEY 680
Query: 764 EIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGI 823
+ V A+ G G SS V T + VP+ PP V E NST + W P P +G
Sbjct: 681 RVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ 740
Query: 824 NQGYKLIAWEPEQEE--------EVTMVTA--RPNFQDSIHVGFVSGLKKFTEYFTSVLC 873
+GY++ E E +V + A RP + +SGL T Y +V
Sbjct: 741 IRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYET-TISGLTPETTYSVTVAA 799
Query: 874 FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWE 933
+TT GDG RS P++V T VPG + + ++T+L + W P E G L GYR+ +
Sbjct: 800 YTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTAL-LQWHPPKELPGELLGYRLQYC 858
Query: 934 EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELP 993
+ + + + VTGL TTY +AA G G+ I + P +LP
Sbjct: 859 RADEARPNTIDFGKD-DQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRT--PEDLP 915
Query: 994 -GPPTNLGISNIGPRSVTLQFRPGYDGKTS---ISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
G P NL ++ + + L + P + + IS +V + E L N
Sbjct: 916 SGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQE---------LQN 966
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
+ L P T Y ++R G+ P S PS + +T+ A N + A
Sbjct: 967 ITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLS-PSIQSRTMPVEQVFA-KNFRVAAAM 1024
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
+TS+ L W +P+ + P + Y + DGH
Sbjct: 1025 KTSVLLSW-EVPDSYKSAVPFKILYNGQSVEVDGH 1058
Score = 181 bits (459), Expect = 7e-45
Identities = 208/834 (24%), Positives = 344/834 (41%), Gaps = 102/834 (12%)
Query: 992 LPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
LP PP +L ++ SVTL + G + A G G +E +
Sbjct: 318 LPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA-AGTEGPFQE-------VDGV 369
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1111
+ L+PF+ Y+FR+ VN +G PPS+ R +T + P P V R S +
Sbjct: 370 ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRA-RTGEQAPSSPPRRVQARMLSAS 428
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEY 1171
++ ++W P PE E NG GY++ Y+ H T+ L Y
Sbjct: 429 TMLVQWEP-PE-EPNGLVR--GYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITY 484
Query: 1172 RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGL 1231
++V AF A+G GP S T+ +T++ VP+ P + A + + + + W +P +R
Sbjct: 485 SLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ-PADFQAEVESDTRIQLSWL-LPPQER--- 539
Query: 1232 VLGYKVMY-KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP 1290
++ Y+++Y +D D Q + V + + S L L LY Q+ A + +G G + P
Sbjct: 540 IIMYELVYWAAEDEDQQHK---VTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFT-P 595
Query: 1291 PILERTLDDVPG-PPMGILFPEVRTTSVRLIWQPPAAP--NGIILAYQITHR-LNTTTAN 1346
I RT P PP ++ + +T+VR+ W PP A NG+I Y + + ++
Sbjct: 596 TIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRG 655
Query: 1347 TATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRP 1406
V+ ++ + GL+ + Y + A T G G + ++V T++ D P P R
Sbjct: 656 RHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDE-DVPSGPPRK 714
Query: 1407 MVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPSGR---------WALHSASVS 1455
V+ E + + +V + W+ S +R Y + L +G L A
Sbjct: 715 -VEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWR 773
Query: 1456 HNASS---FIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTP 1512
S + L P T+Y V A GD S+ + +TT A P ++S T
Sbjct: 774 PEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKP-KIVTTTGAVPGRPTMMISTTA 832
Query: 1513 HTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYS 1572
T L++W PP E + G LLG+R++Y
Sbjct: 833 MNTA--LLQWHPPKE--LPGELLGYRLQY------------------------------C 858
Query: 1573 MRNLSRPSLTQYELDN-------LNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTA 1625
+ +RP+ + D+ L+K Y R++ N G G +E+ E +P+
Sbjct: 859 RADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE-KEIRTPEDLPSG 917
Query: 1626 APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSV 1685
P+N+ V G T + ++ W+PP L +NG I Y + F + + + T +
Sbjct: 918 FPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT----DTRF 973
Query: 1686 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
L L T Y + V A+ + G GP S Q +T + + + TSV +SWE
Sbjct: 974 TLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE 1033
Query: 1746 APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1799
P Y+ P + +V+V G+S L + DL Y F
Sbjct: 1034 VPD-----------SYKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEYSF 1075
Score = 52.0 bits (123), Expect = 6e-06
Identities = 61/221 (27%), Positives = 85/221 (38%), Gaps = 32/221 (14%)
Query: 1719 TQQAAPSAPSSVKFSELTTTSVNVSWEA----PQFPNGILEGYRLVYEPCSPVDGVSKIV 1774
T +A P P + +E T TSV ++W++ P GI P VDGV+
Sbjct: 314 TVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVA-TT 372
Query: 1775 TVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIEANVTTGPGEGAPGPPGVPII 1833
+ G SP Y FR+ A + GP EA V GE AP P +
Sbjct: 373 RYSIGGLSPF----------SEYAFRVLAVNSIGRGPPSEA-VRARTGEQAPSSPPRRVQ 421
Query: 1834 VRYSSA--IAIHWSSGDPGKGPITRYVIEARPSDE---GLWDILIKDIPKEVSSYTFSMD 1888
R SA + + W + G + Y + P W D + ++
Sbjct: 422 ARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTD-----AGLLTTVG 476
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPS-----SPSQSVPAQKAN 1924
L PG++Y RV+A G G PS Q VPAQ A+
Sbjct: 477 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPAD 517
Score = 38.9 bits (89), Expect = 0.056
Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 14/116 (12%)
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSGDPGKGPITRYVIEARPSD-EG 1867
E A VT + P PP + ++V ++A + + W SG+ P+T Y I+ R + EG
Sbjct: 308 EATAQVTV---KALPKPP-IDLVVTETTATSVTLTWDSGN--SEPVTYYGIQYRAAGTEG 361
Query: 1868 LWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKA 1923
+ + V++ +S+ L P Y FRV+AVN G G PS ++ ++A
Sbjct: 362 PFQEV-----DGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQA 412
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 251 bits (641), Expect = 5e-66
Identities = 279/1029 (27%), Positives = 442/1029 (42%), Gaps = 111/1029 (10%)
Query: 233 VTLECVANAR---PLIKLHIIWKKDGVLLSGGISDHNRRLT-----IPNPTGS-----DA 279
V L+C A + P+IK WKKDG+ L+ G+ + ++L+ I N S D
Sbjct: 57 VLLDCSAESDRGVPVIK----WKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDE 112
Query: 280 GYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPS 339
G Y+CEA L S + R A ++V P +F+ + E +TA M V + C+ G P P+
Sbjct: 113 GLYQCEASLGDSG-SIISRTAKVAVAGPLRFLSQTES-VTAFMGDTVLLKCEVIGEPMPT 170
Query: 340 ITWYKDAA-VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT 398
I W K+ + + +R G LQIS L P D G+++C ARN A +T V
Sbjct: 171 IHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASS-RTGNEAEVR 229
Query: 399 SIA-PNITRG------PLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPR 451
++ P + R P + I+G VL C SG P P+ TW +GE ++ ++ +
Sbjct: 230 ILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVI---QLRSKK 286
Query: 452 FTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGT 511
++ L +LLIS D+G YTC+ T ASA+L V P + +
Sbjct: 287 YSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESM 346
Query: 512 QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRV 571
C V+ P T+ W K+G + + ++ +L I D G Y C
Sbjct: 347 DIEFECTVSGKPVPTVN--WMKNGDVVIPSDY--FQIVGGSNLRILGVVKSDEGFYQCVA 402
Query: 572 ISAGGNDSRSAHLRVRQ--------LPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLI 623
+ GN SA L V + LP AP V L V R + L+W P + +
Sbjct: 403 ENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVL--VSSRFVRLSWRPPAEAKGNIQ 460
Query: 624 RYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERV 683
+ + S L + P + +TV L P Y FR+ A N+ G G+ S+ +
Sbjct: 461 TFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVA 520
Query: 684 SLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKN 743
+ PE P +N+ A + SI+I W+PP ++ NG ++GY R + G + +N
Sbjct: 521 TQPELQVPGPVENLQAVSTSPTSILITWEPP--AYANGPVQGY--RLFCTEVSTGKE-QN 575
Query: 744 ITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEAT 803
I + D + LE L +T Y + AYN G GV + +T TL VP+ PP NV E
Sbjct: 576 I-EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVV 634
Query: 804 NSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKK 863
NS +I+ +W P NG GYK+ + + E M T PN ++ F +GL+K
Sbjct: 635 NSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGE--METLEPN---NLWYLF-TGLEK 688
Query: 864 FTEYFTSVLCFTTPGDGPRS------TPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
++Y V T G GP S TP+ VP L + + +SW
Sbjct: 689 GSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCII-MSWTP 747
Query: 918 PGEKNGILTGYRIS------WEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAM 971
P N ++ GY I + E R +++ + Y + L + + Y I + A
Sbjct: 748 PLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRY--------YSIERLESSSHYVISLKAF 799
Query: 972 TSKGQG---QVSASTISSGVP-------PELPGPPTNLG------ISNIGPRSVTL---Q 1012
+ G+G SA+T S P P L PT++ + +G ++V L
Sbjct: 800 NNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDA 859
Query: 1013 FRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQL-SNEPDARSMEVPDLNPFTCYSFR 1070
R + D ++ E ++ V + + S + + S L P T Y F
Sbjct: 860 VRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFS 919
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSL--RTASETSLWLRWMPLPEMEYNGN 1128
+ +S S + T +A P AP ++++ R ++ + W P +E NG
Sbjct: 920 VMVTKNRRSSTWSMTAH-ATTYEAAPTSAPKDLTVITREGKPRAVIVSWQ--PPLEANG- 975
Query: 1129 PESVGYKIKYSRSDGHGKTLSHVVQDRVERD---YTIEDLEEWTEYRVQVQAFNAIGSGP 1185
+ Y + Y+ + + + + D + I DL T Y ++QA N+ G GP
Sbjct: 976 -KITAYILFYTLD--KNIPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSKGVGP 1032
Query: 1186 WSQTVVGRT 1194
S ++ RT
Sbjct: 1033 LSDPILFRT 1041
Score = 157 bits (397), Expect = 1e-37
Identities = 191/708 (26%), Positives = 285/708 (40%), Gaps = 105/708 (14%)
Query: 954 RVTGLTALTTYTIEVAAMTSKGQGQVSASTI--SSGVPPE--LPGPPTNLGISNIGPRSV 1009
R+ G+ + A G Q SA I +P LP P ++ + R V
Sbjct: 386 RILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFV 445
Query: 1010 TLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSF 1069
L +RP + K +I + V G+ E L + +P + + V +L P Y+F
Sbjct: 446 RLSWRPPAEAKGNIQTFTVF--FSREGDNRERALN---TTQPGSLQLTVGNLKPEAMYTF 500
Query: 1070 RMRQVNIVGTSPPSQPSRKIQT---LQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYN 1126
R+ N G SQP K+ T LQ P + N+ + S TS+ + W P Y
Sbjct: 501 RVVAYNEWGPGESSQPI-KVATQPELQVPGPVE--NLQAVSTSPTSILITWEP---PAYA 554
Query: 1127 GNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD---YTIEDLEEWTEYRVQVQAFNAIGS 1183
P GY++ + GK + +E D Y +E L+++TEY ++ A+N G
Sbjct: 555 NGPVQ-GYRL-FCTEVSTGK------EQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGP 606
Query: 1184 GPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYK--- 1240
G + + T VPS+ P NVS S S+ V W P +NG + GYK+ ++
Sbjct: 607 GVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTT 666
Query: 1241 ---EKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSH---PPILE 1294
E ++ W + TGL K Y QV A T G G PS+ E
Sbjct: 667 RRGEMETLEPNNLWYL---------FTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPE 717
Query: 1295 RTLDD--VPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEV 1352
LD+ VP P L +T + + W PP PN ++ Y I + + + A T V+
Sbjct: 718 NDLDESQVPDQPSS-LHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVD- 775
Query: 1353 LAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPP--------- 1403
R Y+ L+ S Y+ + A G G T D P
Sbjct: 776 --SKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDF 833
Query: 1404 -------SRPMVQQEDVRA-----RSVLLSWE----PGSDGLSPVRYYTIQTRELPSGRW 1447
S PM+ V+A +V +SW P + S VR YT++ R S
Sbjct: 834 PTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASA 893
Query: 1448 ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
S + + S+ LKP T Y+F V T + S +S + + TT +AAP AP
Sbjct: 894 KYKSEDTT--SLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHA-TTYEAAPTSAPKD 950
Query: 1508 LSVTPH--TTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWA 1565
L+V +V++ WQPP E NG + + + Y TL N P W
Sbjct: 951 LTVITREGKPRAVIVSWQPPLE--ANGKITAYILFY-----------TL-DKNIPIDDWI 996
Query: 1566 ELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPP 1613
M +S LT +++ +LN Y R+ N+ G GP S P
Sbjct: 997 -------METISGDRLT-HQIMDLNLDTMYYFRIQARNSKGVGPLSDP 1036
Score = 136 bits (343), Expect = 2e-31
Identities = 155/640 (24%), Positives = 252/640 (39%), Gaps = 82/640 (12%)
Query: 911 LKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
+++SW+ P E G + + + + R + +L+ V L YT V A
Sbjct: 445 VRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVA 504
Query: 971 MTSKGQGQVSASTISSGVPPEL--PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLV 1028
G G+ S+ I PEL PGP NL + P S+ + + P + + +
Sbjct: 505 YNEWGPGE-SSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRL 563
Query: 1029 EAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
V G+E + E D S ++ L FT YS R N G S
Sbjct: 564 FCT--EVSTGKEQNI------EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPG-VSTDDIT 614
Query: 1089 IQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
+ TL P P NVSL + S+ + W+P P NG GYKI+ H KT
Sbjct: 615 VVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNG--FITGYKIR------HRKTT 666
Query: 1149 SHVVQDRVERD---YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRES--VPSSGP 1203
+ +E + Y LE+ ++Y QV A G+GP S T E+ S P
Sbjct: 667 RRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVP 726
Query: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMY-------KEKDSDTQPRFWLVEGN 1256
S+L + + S P + N +V GY + Y + D++ R++ +E
Sbjct: 727 DQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERL 786
Query: 1257 SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT-------------LDDVPG- 1302
S S Y + + AF G+G P + R+ LDD P
Sbjct: 787 ESSSH----------YVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTS 836
Query: 1303 ---------PPMGILFPEVRTTSVRLIWQPPAAPNG--IILAYQITHRLNTTTANTATVE 1351
PP+G+ + +VR+ W + P T R T+ + +A +
Sbjct: 837 VPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYK 896
Query: 1352 VLAPSARQYTATGLKPESVYLFRI-TAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQ 1410
++ YTATGLKP ++Y F + + R+ + A T E P ++ +
Sbjct: 897 SEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITR 956
Query: 1411 EDVRARSVLLSWEPGSDG----LSPVRYYTIQTRELPSGRWALHSAS---VSHNASSFIV 1463
E + R+V++SW+P + + + +YT+ + +P W + + S ++H +
Sbjct: 957 EG-KPRAVIVSWQPPLEANGKITAYILFYTLD-KNIPIDDWIMETISGDRLTHQIMDLNL 1014
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDE 1503
D T Y FR++A N G S+ T PD+
Sbjct: 1015 D-----TMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDK 1049
Score = 134 bits (336), Expect = 1e-30
Identities = 238/1075 (22%), Positives = 390/1075 (36%), Gaps = 168/1075 (15%)
Query: 28 FKTEPVRTQVHLEGNRLVLTCMAEGSWPLE-FKW----LH-------NNRELTKFSLEYR 75
F +EP V + G ++L C AE + KW +H ++L+ SL +
Sbjct: 42 FLSEP-SDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQ 100
Query: 76 YMITSLD-RTHAGFYRCIVR-NRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIR 133
++ S + G Y+C G+++ R +V VA F + + G+ +++
Sbjct: 101 NILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLK 160
Query: 134 APRIASFPQPQVTWFR---DGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKN 190
I P P + W + D IP SR+ + L I D G Y A N +
Sbjct: 161 CEVIGE-PMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS 219
Query: 191 GDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARP------- 243
+ + + P + P N + G V LEC + P
Sbjct: 220 SRTGNEAEVRI----LSDPGLHRQLYFLQRPSNVVAIEGKDAV-LECCVSGYPPPSFTWL 274
Query: 244 ----LIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG 299
+I+L K LL G L I N T D+G Y C ++ ++ +
Sbjct: 275 RGEEVIQLR---SKKYSLLGGS------NLLISNVTDDDSGMYTCVVTYKNENISA---S 322
Query: 300 AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQ 359
A L+VL PP F+ P ++ A ++ C G P P++ W K+ VV F+
Sbjct: 323 AELTVLVPPWFLNHPS-NLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDY--FQI 379
Query: 360 RNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-------TSIAPNITRGPLDST 412
L+I G+V D G +QC A N AG QTS L V +S+ P+ R +
Sbjct: 380 VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVP-V 438
Query: 413 VIDGMSVVLA----CETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHIS 468
++ V L+ E G + + E G + + GSL ++ ++
Sbjct: 439 LVSSRFVRLSWRPPAEAKGNIQTFTVFFSRE-----GDNRERALNTTQPGSLQLTVGNLK 493
Query: 469 DAGTYT--CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT 526
YT +A N G E+S + V + + P ++ QA V+ P +
Sbjct: 494 PEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVP----GPVENLQA-----VSTSP-TS 543
Query: 527 IRYIWEKDGATLG-------------TESHPRIRLDRNGSLHISQTWSGDIGTYTCRVIS 573
I WE G T I +D L Y+ R ++
Sbjct: 544 ILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVD---GLSYKLEGLKKFTEYSLRFLA 600
Query: 574 -----AGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE 628
G + + + +P AP V+ L V R+I ++W P G +
Sbjct: 601 YNRYGPGVSTDDITVVTLSDVPSAPPQNVS-LEVVNSRSIKVSWLPPPSGTQNGFITGYK 659
Query: 629 MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ----FSKDTERVS 684
+ + +++P GL Y F++ A+ G G ++ +T
Sbjct: 660 IRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPEND 719
Query: 685 LPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI 744
L E P ++ +TN I++ W PP + N +++GYII Y G+ Y
Sbjct: 720 LDESQVPDQPSSLHVRPQTN-CIIMSWTPP--LNPNIVVRGYIIGY---GVGSPYAETVR 773
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV--YSSKVTEWTLQ-------------- 788
D+ +E L ++Y I + A+N+AG GV Y S T
Sbjct: 774 VDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDF 833
Query: 789 -------GVPTVPPGNVHAEATNSTTIRFTW---NAPSPQFINGINQGYKLIAWEPEQEE 838
P +PP V A A +R +W + P Q + + + W
Sbjct: 834 PTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVR--LYTVRWRTSFS- 890
Query: 839 EVTMVTARPNFQDSIHVGFVS-GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGP 897
+A+ +D+ + + + GLK T Y SV+ S T+E P
Sbjct: 891 ----ASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTS 946
Query: 898 VGH---LSFSEILDTSLKVSWQEPGEKNGILTGYRI-----------SWEEYNRTNTRVT 943
+ E ++ VSWQ P E NG +T Y + W + R+T
Sbjct: 947 APKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLT 1006
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN 998
H + ++ L+ T Y + A SKG G +S + + E P N
Sbjct: 1007 HQIMDLNLD---------TMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDKMAN 1052
Score = 117 bits (293), Expect = 1e-25
Identities = 208/925 (22%), Positives = 330/925 (35%), Gaps = 200/925 (21%)
Query: 1197 SVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN 1256
SV S P +V + SS VR S P A+ G + + V + ++ D + R
Sbjct: 426 SVLPSAPRDVVPVLV--SSRFVRLSWRPPAEAKGNIQTFTVFFS-REGDNRERALNTTQP 482
Query: 1257 SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP-PILERTLDDVPGPPMGILFPEVRTT 1315
S + L +Y +V+A+ G G S P + + VPGP + T
Sbjct: 483 GSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPT 542
Query: 1316 SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRI 1375
S+ + W+PPA NG + Y RL T +T + + Y GLK + Y R
Sbjct: 543 SILITWEPPAYANGPVQGY----RLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRF 598
Query: 1376 TAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSP--VR 1433
A R G G + + + V T PP V E V +RS+ +SW P G +
Sbjct: 599 LAYNRYGPGVSTDDITVVTLSDVPSAPPQN--VSLEVVNSRSIKVSWLPPPSGTQNGFIT 656
Query: 1434 YYTIQTREL----------PSGRWALHS-----ASVSHNASSFIVDRLKPFTSYKFRVKA 1478
Y I+ R+ P+ W L + + S S+ V+ P +++
Sbjct: 657 GYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETP 716
Query: 1479 TNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFR 1538
ND+ +S+ PD+ P+ L V P T +++ W PP I ++ G+
Sbjct: 717 ENDLDESQ-------------VPDQ-PSSLHVRPQTNC-IIMSWTPPLNPNI--VVRGYI 759
Query: 1539 IRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIR 1598
I Y G+ +P +AE + S + Y ++ L Y I
Sbjct: 760 IGY--------------GVGSP---YAETVRVDSKQRY-------YSIERLESSSHYVIS 795
Query: 1599 MSVYNAVGEG--------------PSSPPQEVFVGEAVPTAAPR---------NVVVHGA 1635
+ +N GEG P+ P + + PT+ P V
Sbjct: 796 LKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVAL 855
Query: 1636 TATQLDVTW--EPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTG- 1692
T + V+W P + + +++ Y T R +T F A K ++ T
Sbjct: 856 THDAVRVSWADNSVPKNQKTSEVRLY------------TVRWRTSFSASAKYKSEDTTSL 903
Query: 1693 -YTA--------YMVSVAAFNAAGDGPRSTPTQGQTQQAAP-SAPS--SVKFSELTTTSV 1740
YTA Y SV S T +AAP SAP +V E +V
Sbjct: 904 SYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAV 963
Query: 1741 NVSWEAPQFPNGILEGYRLVY--EPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYR 1798
VSW+ P NG + Y L Y + P+D ++ L ++ DL Y
Sbjct: 964 IVSWQPPLEANGKITAYILFYTLDKNIPIDD----WIMETISGDRLTHQIMDLNLDTMYY 1019
Query: 1799 FRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYV 1858
FRI+A+ GP PI+ R + D G
Sbjct: 1020 FRIQAR----------------NSKGVGPLSDPILFRTLKVEHPDKMANDQG-------- 1055
Query: 1859 IEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSV 1918
R D G W + I + +N+ G P SV
Sbjct: 1056 ---RHGDGGYWPVDTNLIDRS----------------------TLNEPPIGQMHPPHGSV 1090
Query: 1919 PAQKANPFYEEWWFLVVIALVGLIFILLLVFVLII--RGQSKKYAKKTDSGNSAKSGALG 1976
QK + ++++ VG+I +L++V V +I R S + KK + ++ K
Sbjct: 1091 TPQKNSNL-----LVIIVVTVGVITVLVVVIVAVICTRRSSAQQRKKRATHSAGKRKG-- 1143
Query: 1977 HSEMMSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDL 2036
S + P L +++ + +KN +PS D + DL
Sbjct: 1144 -----SQKDLRPPDLWIHHEEMEMKNI------------EKPSGTDPAGRDSPIQSCQDL 1186
Query: 2037 IP-AESSSLTEKPSEISDSQGSDSE 2060
P + S S T+ S+ + G D+E
Sbjct: 1187 TPVSHSQSETQLGSKSTSHSGQDTE 1211
Score = 90.1 bits (222), Expect = 2e-17
Identities = 87/344 (25%), Positives = 143/344 (41%), Gaps = 53/344 (15%)
Query: 1474 FRVKATNDIGDSEFSEES-------ESLTTLQAAP-DEAPTILSVTPHTTTSVLIRWQPP 1525
++ A N+ G+++ S + S + L +AP D P ++S + V + W+PP
Sbjct: 398 YQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVS-----SRFVRLSWRPP 452
Query: 1526 AEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYE 1585
AE K G + F + F+ G N A N ++P Q
Sbjct: 453 AEAK--GNIQTFTVF-----------FSREGDNRERAL-----------NTTQPGSLQLT 488
Query: 1586 LDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAP-RNVVVHGATATQLDVTW 1644
+ NL Y R+ YN G G SS P +V + P N+ + T + +TW
Sbjct: 489 VGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITW 548
Query: 1645 EPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFN 1704
EPP NG +QGY+++ E G + + + + S KL+ L +T Y + A+N
Sbjct: 549 EPPAY--ANGPVQGYRLFCTEVSTG----KEQNIEVDGLSYKLEGLKKFTEYSLRFLAYN 602
Query: 1705 AAGDGPRSTPTQGQTQQAAPSA-PSSVKFSELTTTSVNVSWEAPQ--FPNGILEGYRLVY 1761
G G + T PSA P +V + + S+ VSW P NG + GY++ +
Sbjct: 603 RYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRH 662
Query: 1762 EPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1805
++ ++ + LW L +G Y F++ A T
Sbjct: 663 RK------TTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMT 700
Score = 82.0 bits (201), Expect = 6e-15
Identities = 86/311 (27%), Positives = 137/311 (44%), Gaps = 29/311 (9%)
Query: 1613 PQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLT 1672
P+ +V +APR+VV ++ + ++W PP G+IQ + ++F ++ G+
Sbjct: 418 PKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPA--EAKGNIQTFTVFF--SREGDNR 473
Query: 1673 ER-VKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQA--APSAPSS 1729
ER + T + + NL Y V A+N G G S P + TQ P +
Sbjct: 474 ERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVEN 533
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVK 1789
++ + TS+ ++WE P + NG ++GYRL C+ V K ++V G L K++
Sbjct: 534 LQAVSTSPTSILITWEPPAYANGPVQGYRLF---CTEV-STGKEQNIEVDG---LSYKLE 586
Query: 1790 DLAEGVTYRFRIRAKTFTYGPEIEAN----VTTGPGEGAPGPPGVPIIVRYSSAIAIHWS 1845
L + Y R A YGP + + VT AP P V + V S +I + W
Sbjct: 587 GLKKFTEYSLRFLAYN-RYGPGVSTDDITVVTLSDVPSAP-PQNVSLEVVNSRSIKVSWL 644
Query: 1846 SGDPG--KGPITRYVIEARPSD-EGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
G G IT Y I R + G + L E ++ + L+ G Y F+V A
Sbjct: 645 PPPSGTQNGFITGYKIRHRKTTRRGEMETL------EPNNLWYLFTGLEKGSQYSFQVSA 698
Query: 1903 VNDYGFGTPSS 1913
+ G G PS+
Sbjct: 699 MTVNGTGPPSN 709
Score = 49.3 bits (116), Expect = 4e-05
Identities = 47/200 (23%), Positives = 73/200 (36%), Gaps = 9/200 (4%)
Query: 27 YFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY------RYMITS 80
YF P V +EG VL C G P F WL + S +Y +I++
Sbjct: 241 YFLQRPSNV-VAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISN 299
Query: 81 LDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASF 140
+ +G Y C+V + + E+ V F ++ + ++
Sbjct: 300 VTDDDSGMYTCVVTYK-NENISASAELTVLVPPWF-LNHPSNLYAYESMDIEFECTVSGK 357
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPIT 200
P P V W ++G + PS I + L IL V D G Y A N+ ++Q I
Sbjct: 358 PVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV 417
Query: 201 LTVENVGGPADPIAPTIIIP 220
P AP ++P
Sbjct: 418 PKPAIPSSSVLPSAPRDVVP 437
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 248 bits (633), Expect = 5e-65
Identities = 255/1019 (25%), Positives = 419/1019 (41%), Gaps = 69/1019 (6%)
Query: 1 MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKW 60
+W LL+ + L QI + P + R V + + L C A G ++F+W
Sbjct: 8 VWPLLLCSPCLLIQIPEELMEP---PVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW 64
Query: 61 LHNNRELTKFSLEYRYMITSLDRTHAG-----------------FYRCIVRNRMGALLQR 103
R+ F + +T H+G YRC N++G +
Sbjct: 65 ---TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSH 121
Query: 104 QTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDG-RKIPPSSRIA 161
+ + + +E K V GE+ V+ S ++ W I R+
Sbjct: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
Query: 162 ITLENTLVILSTVAPDAGRYYV-QAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIP 220
+ L + + D Y+ A +PI L V+ D P ++ P
Sbjct: 182 MGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR-KPRLLFP 240
Query: 221 PKNTS--VVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS--DHNRRLTIPNPTG 276
++S V + LEC+A P + + + G + + ++ +HN+ L +
Sbjct: 241 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWL-RPSGPMPADRVTYQNHNKTLQLLKVGE 299
Query: 277 SDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVP 336
D G Y C L +S+ S Y++V P ++ +P+ H+ E + CQ +G P
Sbjct: 300 EDDGEYRC---LAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE-TARLDCQVQGRP 355
Query: 337 PPSITW-YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYL 395
P +TW V E+ K ++R + G L +S + P DT + QC ARN G + + Y+
Sbjct: 356 QPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQCEARNRHGLLLANAYI 414
Query: 396 AVTSIAPNI-TRGPLDSTVIDGMSVVLACETSGAPRPAITW--QKGERILASGSVQLPRF 452
V + I T + G + L C+ GAP P++ W + G +L Q RF
Sbjct: 415 YVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-----QDERF 469
Query: 453 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQ 512
P +G+L I +D G Y CLA N + A+L V T+IT+ P+ KG++
Sbjct: 470 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 529
Query: 513 ASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVI 572
+ C + DP + W DG L +G L I D G Y+C V
Sbjct: 530 VTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC-VA 588
Query: 573 SAGGN--DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMS 630
S + +SR+ L V P ++ L + + + ++W+ D N+P+ +Y +E
Sbjct: 589 STELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFE 648
Query: 631 ENN-AP--WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPE 687
+ AP W L V TS T+K L P Y FR+ A+N G G+ S +E V PE
Sbjct: 649 DKEMAPEKW-YSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPE 706
Query: 688 EPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
P P +V G +++I W+P N Y +++ G +Q + ++D
Sbjct: 707 AAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDP 766
Query: 748 DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
L++ + + YEI+V A NS G G ++ + P P E NS+
Sbjct: 767 ---FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSA 823
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG------FVSGL 861
+ W + G +GY + W +E + R +D + V +SGL
Sbjct: 824 VLVKWRPVDLAQVKGHLRGYNVTYW---REGSQRKHSKRHIHKDHVVVPANTTSVILSGL 880
Query: 862 KKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEK 921
+ ++ Y V F G GP S T E VPG L +TSL + WQ P
Sbjct: 881 RPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSH 939
Query: 922 NGILTGYRISWEEYNRTNT-RVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSKGQGQ 978
NG+LTGY +S+ + +++ L + L + +T L+ Y ++ A T +G G+
Sbjct: 940 NGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGE 998
Score = 149 bits (377), Expect = 2e-35
Identities = 154/598 (25%), Positives = 257/598 (42%), Gaps = 67/598 (11%)
Query: 1400 PQPPSRPMVQQEDVRARS-VLLSWEPGSDGLSPVRYYTIQ--TRELPSGRWALHSASVSH 1456
P P R ++ + +S V +SW P D +P+ Y I+ +E+ +W +
Sbjct: 607 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN 666
Query: 1457 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTT 1516
S+ + +L P+ Y FRV A N G E S SE++ T +AAP++ P + + TT
Sbjct: 667 QTSTTL--KLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETT 724
Query: 1517 SVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL 1576
+++I W+P N + +R+++R +G RG W E + +
Sbjct: 725 NMVITWKPLRWMDWNAPQVQYRVQWRP---QGTRG-----------PWQE-------QIV 763
Query: 1577 SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGAT 1636
S P L + N + YEI++ N+ G+GP + GE P A P +
Sbjct: 764 SDPFLV---VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILN 820
Query: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWE--AQRGNLTERVKTLFLA----ENSVKLKNL 1690
++ + V W P L G ++GY + +W +QR + + + SV L L
Sbjct: 821 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 880
Query: 1691 TGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Y++Y + V AFN G GP S T T + P P ++ + TS+ + W+ P
Sbjct: 881 RPYSSYHLEVQAFNGRGSGPASEFT-FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSH 939
Query: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
NG+L GY L Y P +G ++ +++ + DL+ + YRF+++A T GP
Sbjct: 940 NGVLTGYVLSYHPLD--EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATT-KEGP 996
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS--SGDPGKGPIT---RYVIEARPSD 1865
EA V G G G+ S+ ++S S P +G + +A +
Sbjct: 997 G-EAIVREG---GTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEE 1052
Query: 1866 EGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV---------IAVNDYGFGTPSSPSQ 1916
+G + + + SSYT D L+P Y+ + +AV G G P
Sbjct: 1053 KGGASLSPQYVSYNQSSYT-QWD-LQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLP-- 1108
Query: 1917 SVPAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGA 1974
PA F E WF+ ++ + L+ ++LL+ I R + KY+ K S A
Sbjct: 1109 --PA----GFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEA 1160
Score = 146 bits (369), Expect = 2e-34
Identities = 246/1090 (22%), Positives = 416/1090 (38%), Gaps = 117/1090 (10%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITL-----ENTLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
P+ Q W RDG P + +T+ + I + A R+ Q + NK
Sbjct: 58 PEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRF--QGIYRCFASNKL 115
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIK-LHIIWKKD 254
++ + + A P P + P V G S V L C N P + L I W
Sbjct: 116 GTAMSHEIRLMAEGA-PKWPKETVKP--VEVEEGES-VVLPC--NPPPSAEPLRIYWMNS 169
Query: 255 GVLL----SGGISDHNRRLTIPNPTGSDA-GYYECEA-------VLRSSSVPSVVRGAYL 302
+L N L N SD Y C A +++ + V+
Sbjct: 170 KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNS 229
Query: 303 SVLEPPQ--FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
+ P+ F H+ A + + + C A+G P P+I W + + + +++T Q
Sbjct: 230 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY--QN 287
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
++ LQ+ + +D G ++C A N+ G + + Y+ V + AP P G +
Sbjct: 288 HNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA-APYWLHKPQSHLYGPGETAR 346
Query: 421 LACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATN 479
L C+ G P+P +TW+ G + Q R ++ G+L++S SD C A N
Sbjct: 347 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYR---IQRGALILSNVQPSDTMVTQCEARN 403
Query: 480 SRGVDEASADL-VVWARTRI-TKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
G+ A+A + VV +I T Q ++G+ A ++C P +++++ ++DG T
Sbjct: 404 RHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTT 462
Query: 538 LGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
+ + R NG+L I + D G Y C + N + A+L+V+ + P
Sbjct: 463 VLQDE--RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP- 519
Query: 598 ATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVP 657
ST+E++ +T+T + L I + L + G +
Sbjct: 520 --RSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFIEDGRLV 572
Query: 658 ARSYQFRLCAVNDVGKGQFSKDTE------RVSLPEEPPTAPPQNVIASGR---TNQSIM 708
S + +D G TE R L P ++ S T +
Sbjct: 573 IHSLDY-----SDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVR 627
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVG--YQFKNITDADVNNLLLEDLIIWTNYEIE 766
+ W P E H N ++ Y I + + Y + + L L + +Y
Sbjct: 628 VSWSPA-EDH-NAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL--KLSPYVHYTFR 683
Query: 767 VAAYNSAGLGVYSS-KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTW--------NAPSP 817
V A N G G S T T + P P +V E +T + TW NAP
Sbjct: 684 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQV 743
Query: 818 QFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF--VSGLKKFTEYFTSVLCFT 875
Q+ + W P+ T P + + F VS F Y V
Sbjct: 744 QY---------RVQWRPQG-------TRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVN 787
Query: 876 TPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS-LKVSWQ--EPGEKNGILTGYRIS- 931
+ G GP + + ED P + L EIL++S + V W+ + + G L GY ++
Sbjct: 788 SQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTY 847
Query: 932 WEEYNRTNTRVTHY------LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
W E ++ H +P T ++GL ++Y +EV A +G G S T S
Sbjct: 848 WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFS 907
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIH 1045
+ P +PG P L + S+ L+++P ++ +++ + EG + L
Sbjct: 908 T--PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH--PLDEGGKGQLSF 963
Query: 1046 QLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSL 1105
L +P+ R+ + DL+P Y F+++ G L D N+S
Sbjct: 964 NL-RDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF--GNIS- 1019
Query: 1106 RTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDL 1165
TA E + W+P E + N + K + G +LS + YT DL
Sbjct: 1020 ATAGENYSVVSWVP-KEGQCNFRFHIL---FKALGEEKGGASLSPQYVSYNQSSYTQWDL 1075
Query: 1166 EEWTEYRVQV 1175
+ T+Y + +
Sbjct: 1076 QPDTDYEIHL 1085
Score = 145 bits (367), Expect = 3e-34
Identities = 127/495 (25%), Positives = 213/495 (43%), Gaps = 27/495 (5%)
Query: 993 PGPPTNLGISNIG---PRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
PGP L +S++ V + + P D I ++ +E + + E+W + L
Sbjct: 607 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP-EKW---YSLGK 662
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
P ++ L+P+ Y+FR+ +N G PS S + T +A P+ P +V
Sbjct: 663 VPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 722
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
T++ + W PL M++N V Y++++ G +V D + + +
Sbjct: 723 TTNMVITWKPLRWMDWNA--PQVQYRVQWRPQGTRGPWQEQIVSDPF---LVVSNTSTFV 777
Query: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRN 1229
Y ++VQA N+ G GP Q +G + E P + P SS++LV+W V A
Sbjct: 778 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 837
Query: 1230 GLVLGYKVMYKEKDSDTQ------PRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
G + GY V Y + S + + +V ++ S L+GL Y Y ++V AF G
Sbjct: 838 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 897
Query: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQIT-HRLNT 1342
G S T + VPG P + TS+ L WQPP + NG++ Y ++ H L+
Sbjct: 898 SGPASE--FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 955
Query: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402
+ + P R + T L P Y F++ A T++G GEA T
Sbjct: 956 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1015
Query: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTI-QTRELPSGRWALHSASVSHNASSF 1461
+ E+ ++SW P +G R++ + + G +L VS+N SS+
Sbjct: 1016 GNISATAGENYS----VVSWVP-KEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSY 1070
Query: 1462 IVDRLKPFTSYKFRV 1476
L+P T Y+ +
Sbjct: 1071 TQWDLQPDTDYEIHL 1085
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 248 bits (632), Expect = 6e-65
Identities = 256/1021 (25%), Positives = 419/1021 (41%), Gaps = 68/1021 (6%)
Query: 1 MWGLLIWTLLALHQIRAARAQDDVS--PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEF 58
+W LL+ + L QI V P + R V + + L C A G ++F
Sbjct: 8 VWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQF 67
Query: 59 KWLHNNRELTKFSLEYRYMITSLDRTHAG-----------------FYRCIVRNRMGALL 101
+W R+ F + +T H+G YRC N++G +
Sbjct: 68 RW---TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAM 124
Query: 102 QRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDG-RKIPPSSR 159
+ + + +E K V GE+ V+ S ++ W I R
Sbjct: 125 SHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDER 184
Query: 160 IAITLENTLVILSTVAPDAGRYYV-QAVNDKNGDNKTSQPITLTVENVGGPADPIAPTII 218
+ + L + + D Y+ A +PI L V+ D P ++
Sbjct: 185 VTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR-KPRLL 243
Query: 219 IPPKNTS--VVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS--DHNRRLTIPNP 274
P ++S V + LEC+A P + + + G + + ++ +HN+ L +
Sbjct: 244 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL-RPSGPMPADRVTYQNHNKTLQLLKV 302
Query: 275 TGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKG 334
D G Y C L +S+ S Y++V P ++ +P+ H+ E + CQ +G
Sbjct: 303 GEEDDGEYRC---LAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE-TARLDCQVQG 358
Query: 335 VPPPSITW-YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTST 393
P P +TW V E+ K ++R + G L +S + P DT + QC ARN G + +
Sbjct: 359 RPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQCEARNRHGLLLANA 417
Query: 394 YLAVTSIAPNI-TRGPLDSTVIDGMSVVLACETSGAPRPAITW--QKGERILASGSVQLP 450
Y+ V + I T + G + L C+ GAP P++ W + G +L Q
Sbjct: 418 YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-----QDE 472
Query: 451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKG 510
RF P +G+L I +D G Y CLA N + A+L V T+IT+ P+ KG
Sbjct: 473 RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG 532
Query: 511 TQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCR 570
++ + C + DP + W DG L +G L I D G Y+C
Sbjct: 533 SRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC- 591
Query: 571 VISAGGN--DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE 628
V S + +SR+ L V P ++ L + + + ++W+ D N+P+ +Y +E
Sbjct: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
Query: 629 MSENN-AP--WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL 685
+ AP W L V TS T+K L P Y FR+ A+N G G+ S +E V
Sbjct: 652 FEDKEMAPEKW-YSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVT 709
Query: 686 PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNIT 745
PE P P +V G +++I W+P N Y +++ G +Q + ++
Sbjct: 710 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 769
Query: 746 DADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNS 805
D L++ + + YEI+V A NS G G ++ + P P E NS
Sbjct: 770 DP---FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNS 826
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG------FVS 859
+ + W + G +GY + W +E + R +D + V +S
Sbjct: 827 SAVLVKWRPVDLAQVKGHLRGYNVTYW---REGSQRKHSKRHIHKDHVVVPANTTSVILS 883
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
GL+ ++ Y V F G GP S T E VPG L +TSL + WQ P
Sbjct: 884 GLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPL 942
Query: 920 EKNGILTGYRISWEEYNRTNT-RVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSKGQG 977
NG+LTGY +S+ + +++ L + L + +T L+ Y ++ A T +G G
Sbjct: 943 SHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
Query: 978 Q 978
+
Sbjct: 1003 E 1003
Score = 149 bits (377), Expect = 2e-35
Identities = 154/598 (25%), Positives = 257/598 (42%), Gaps = 67/598 (11%)
Query: 1400 PQPPSRPMVQQEDVRARS-VLLSWEPGSDGLSPVRYYTIQ--TRELPSGRWALHSASVSH 1456
P P R ++ + +S V +SW P D +P+ Y I+ +E+ +W +
Sbjct: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN 671
Query: 1457 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTT 1516
S+ + +L P+ Y FRV A N G E S SE++ T +AAP++ P + + TT
Sbjct: 672 QTSTTL--KLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETT 729
Query: 1517 SVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL 1576
+++I W+P N + +R+++R +G RG W E + +
Sbjct: 730 NMVITWKPLRWMDWNAPQVQYRVQWRP---QGTRG-----------PWQE-------QIV 768
Query: 1577 SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGAT 1636
S P L + N + YEI++ N+ G+GP + GE P A P +
Sbjct: 769 SDPFLV---VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILN 825
Query: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWE--AQRGNLTERVKTLFLA----ENSVKLKNL 1690
++ + V W P L G ++GY + +W +QR + + + SV L L
Sbjct: 826 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 885
Query: 1691 TGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Y++Y + V AFN G GP S T T + P P ++ + TS+ + W+ P
Sbjct: 886 RPYSSYHLEVQAFNGRGSGPASEFT-FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSH 944
Query: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
NG+L GY L Y P +G ++ +++ + DL+ + YRF+++A T GP
Sbjct: 945 NGVLTGYVLSYHPLD--EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATT-KEGP 1001
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS--SGDPGKGPIT---RYVIEARPSD 1865
EA V G G G+ S+ ++S S P +G + +A +
Sbjct: 1002 G-EAIVREG---GTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEE 1057
Query: 1866 EGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV---------IAVNDYGFGTPSSPSQ 1916
+G + + + SSYT D L+P Y+ + +AV G G P
Sbjct: 1058 KGGASLSPQYVSYNQSSYT-QWD-LQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLP-- 1113
Query: 1917 SVPAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGA 1974
PA F E WF+ ++ + L+ ++LL+ I R + KY+ K S A
Sbjct: 1114 --PA----GFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEA 1165
Score = 146 bits (369), Expect = 2e-34
Identities = 246/1090 (22%), Positives = 416/1090 (38%), Gaps = 117/1090 (10%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITL-----ENTLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
P+ Q W RDG P + +T+ + I + A R+ Q + NK
Sbjct: 63 PEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRF--QGIYRCFASNKL 120
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIK-LHIIWKKD 254
++ + + A P P + P V G S V L C N P + L I W
Sbjct: 121 GTAMSHEIRLMAEGA-PKWPKETVKP--VEVEEGES-VVLPC--NPPPSAEPLRIYWMNS 174
Query: 255 GVLL----SGGISDHNRRLTIPNPTGSDA-GYYECEA-------VLRSSSVPSVVRGAYL 302
+L N L N SD Y C A +++ + V+
Sbjct: 175 KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNS 234
Query: 303 SVLEPPQ--FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
+ P+ F H+ A + + + C A+G P P+I W + + + +++T Q
Sbjct: 235 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY--QN 292
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
++ LQ+ + +D G ++C A N+ G + + Y+ V + AP P G +
Sbjct: 293 HNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA-APYWLHKPQSHLYGPGETAR 351
Query: 421 LACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATN 479
L C+ G P+P +TW+ G + Q R ++ G+L++S SD C A N
Sbjct: 352 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYR---IQRGALILSNVQPSDTMVTQCEARN 408
Query: 480 SRGVDEASADL-VVWARTRI-TKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
G+ A+A + VV +I T Q ++G+ A ++C P +++++ ++DG T
Sbjct: 409 RHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTT 467
Query: 538 LGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
+ + R NG+L I + D G Y C + N + A+L+V+ + P
Sbjct: 468 VLQDE--RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP- 524
Query: 598 ATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVP 657
ST+E++ +T+T + L I + L + G +
Sbjct: 525 --RSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFIEDGRLV 577
Query: 658 ARSYQFRLCAVNDVGKGQFSKDTE------RVSLPEEPPTAPPQNVIASGR---TNQSIM 708
S + +D G TE R L P ++ S T +
Sbjct: 578 IHSLDY-----SDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVR 632
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVG--YQFKNITDADVNNLLLEDLIIWTNYEIE 766
+ W P E H N ++ Y I + + Y + + L L + +Y
Sbjct: 633 VSWSPA-EDH-NAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL--KLSPYVHYTFR 688
Query: 767 VAAYNSAGLGVYSS-KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTW--------NAPSP 817
V A N G G S T T + P P +V E +T + TW NAP
Sbjct: 689 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQV 748
Query: 818 QFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF--VSGLKKFTEYFTSVLCFT 875
Q+ + W P+ T P + + F VS F Y V
Sbjct: 749 QY---------RVQWRPQG-------TRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVN 792
Query: 876 TPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS-LKVSWQ--EPGEKNGILTGYRIS- 931
+ G GP + + ED P + L EIL++S + V W+ + + G L GY ++
Sbjct: 793 SQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTY 852
Query: 932 WEEYNRTNTRVTHY------LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
W E ++ H +P T ++GL ++Y +EV A +G G S T S
Sbjct: 853 WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFS 912
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIH 1045
+ P +PG P L + S+ L+++P ++ +++ + EG + L
Sbjct: 913 T--PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH--PLDEGGKGQLSF 968
Query: 1046 QLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSL 1105
L +P+ R+ + DL+P Y F+++ G L D N+S
Sbjct: 969 NL-RDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF--GNIS- 1024
Query: 1106 RTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDL 1165
TA E + W+P E + N + K + G +LS + YT DL
Sbjct: 1025 ATAGENYSVVSWVP-KEGQCNFRFHIL---FKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
Query: 1166 EEWTEYRVQV 1175
+ T+Y + +
Sbjct: 1081 QPDTDYEIHL 1090
Score = 145 bits (367), Expect = 3e-34
Identities = 127/495 (25%), Positives = 213/495 (43%), Gaps = 27/495 (5%)
Query: 993 PGPPTNLGISNIG---PRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
PGP L +S++ V + + P D I ++ +E + + E+W + L
Sbjct: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP-EKW---YSLGK 667
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
P ++ L+P+ Y+FR+ +N G PS S + T +A P+ P +V
Sbjct: 668 VPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 727
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
T++ + W PL M++N V Y++++ G +V D + + +
Sbjct: 728 TTNMVITWKPLRWMDWNA--PQVQYRVQWRPQGTRGPWQEQIVSDPF---LVVSNTSTFV 782
Query: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRN 1229
Y ++VQA N+ G GP Q +G + E P + P SS++LV+W V A
Sbjct: 783 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 842
Query: 1230 GLVLGYKVMYKEKDSDTQ------PRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
G + GY V Y + S + + +V ++ S L+GL Y Y ++V AF G
Sbjct: 843 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 902
Query: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQIT-HRLNT 1342
G S T + VPG P + TS+ L WQPP + NG++ Y ++ H L+
Sbjct: 903 SGPASE--FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
Query: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402
+ + P R + T L P Y F++ A T++G GEA T
Sbjct: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
Query: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTI-QTRELPSGRWALHSASVSHNASSF 1461
+ E+ ++SW P +G R++ + + G +L VS+N SS+
Sbjct: 1021 GNISATAGENYS----VVSWVP-KEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSY 1075
Query: 1462 IVDRLKPFTSYKFRV 1476
L+P T Y+ +
Sbjct: 1076 TQWDLQPDTDYEIHL 1090
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 248 bits (632), Expect = 6e-65
Identities = 256/1021 (25%), Positives = 419/1021 (41%), Gaps = 68/1021 (6%)
Query: 1 MWGLLIWTLLALHQIRAARAQDDVS--PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEF 58
+W LL+ + L QI V P + R V + + L C A G ++F
Sbjct: 8 VWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQF 67
Query: 59 KWLHNNRELTKFSLEYRYMITSLDRTHAG-----------------FYRCIVRNRMGALL 101
+W R+ F + +T H+G YRC N++G +
Sbjct: 68 RW---TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAM 124
Query: 102 QRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDG-RKIPPSSR 159
+ + + +E K V GE+ V+ S ++ W I R
Sbjct: 125 SHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDER 184
Query: 160 IAITLENTLVILSTVAPDAGRYYV-QAVNDKNGDNKTSQPITLTVENVGGPADPIAPTII 218
+ + L + + D Y+ A +PI L V+ D P ++
Sbjct: 185 VTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR-KPRLL 243
Query: 219 IPPKNTS--VVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS--DHNRRLTIPNP 274
P ++S V + LEC+A P + + + G + + ++ +HN+ L +
Sbjct: 244 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL-RPSGPMPADRVTYQNHNKTLQLLKV 302
Query: 275 TGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKG 334
D G Y C L +S+ S Y++V P ++ +P+ H+ E + CQ +G
Sbjct: 303 GEEDDGEYRC---LAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE-TARLDCQVQG 358
Query: 335 VPPPSITW-YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTST 393
P P +TW V E+ K ++R + G L +S + P DT + QC ARN G + +
Sbjct: 359 RPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQCEARNRHGLLLANA 417
Query: 394 YLAVTSIAPNI-TRGPLDSTVIDGMSVVLACETSGAPRPAITW--QKGERILASGSVQLP 450
Y+ V + I T + G + L C+ GAP P++ W + G +L Q
Sbjct: 418 YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-----QDE 472
Query: 451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKG 510
RF P +G+L I +D G Y CLA N + A+L V T+IT+ P+ KG
Sbjct: 473 RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG 532
Query: 511 TQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCR 570
++ + C + DP + W DG L +G L I D G Y+C
Sbjct: 533 SRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC- 591
Query: 571 VISAGGN--DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE 628
V S + +SR+ L V P ++ L + + + ++W+ D N+P+ +Y +E
Sbjct: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
Query: 629 MSENN-AP--WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL 685
+ AP W L V TS T+K L P Y FR+ A+N G G+ S +E V
Sbjct: 652 FEDKEMAPEKW-YSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVT 709
Query: 686 PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNIT 745
PE P P +V G +++I W+P N Y +++ G +Q + ++
Sbjct: 710 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 769
Query: 746 DADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNS 805
D L++ + + YEI+V A NS G G ++ + P P E NS
Sbjct: 770 DP---FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNS 826
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG------FVS 859
+ + W + G +GY + W +E + R +D + V +S
Sbjct: 827 SAVLVKWRPVDLAQVKGHLRGYNVTYW---REGSQRKHSKRHIHKDHVVVPANTTSVILS 883
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
GL+ ++ Y V F G GP S T E VPG L +TSL + WQ P
Sbjct: 884 GLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPL 942
Query: 920 EKNGILTGYRISWEEYNRTNT-RVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSKGQG 977
NG+LTGY +S+ + +++ L + L + +T L+ Y ++ A T +G G
Sbjct: 943 SHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
Query: 978 Q 978
+
Sbjct: 1003 E 1003
Score = 150 bits (378), Expect = 2e-35
Identities = 161/633 (25%), Positives = 269/633 (42%), Gaps = 70/633 (11%)
Query: 1400 PQPPSRPMVQQEDVRARS-VLLSWEPGSDGLSPVRYYTIQ--TRELPSGRWALHSASVSH 1456
P P R ++ + +S V +SW P D +P+ Y I+ +E+ +W +
Sbjct: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN 671
Query: 1457 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTT 1516
S+ + +L P+ Y FRV A N G E S SE++ T +AAP++ P + + TT
Sbjct: 672 QTSTTL--KLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETT 729
Query: 1517 SVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL 1576
+++I W+P N + +R+++R +G RG W E + +
Sbjct: 730 NMVITWKPLRWMDWNAPQVQYRVQWRP---QGTRG-----------PWQE-------QIV 768
Query: 1577 SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGAT 1636
S P L + N + YEI++ N+ G+GP + GE P A P +
Sbjct: 769 SDPFLV---VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILN 825
Query: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWE--AQRGNLTERVKTLFLA----ENSVKLKNL 1690
++ + V W P L G ++GY + +W +QR + + + SV L L
Sbjct: 826 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 885
Query: 1691 TGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Y++Y + V AFN G GP S T T + P P ++ + TS+ + W+ P
Sbjct: 886 RPYSSYHLEVQAFNGRGSGPASEFT-FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSH 944
Query: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
NG+L GY L Y P +G ++ +++ + DL+ + YRF+++A T GP
Sbjct: 945 NGVLTGYVLSYHPLD--EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATT-KEGP 1001
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS--SGDPGKGPIT---RYVIEARPSD 1865
EA V G G G+ S+ ++S S P +G + +A +
Sbjct: 1002 G-EAIVREG---GTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEE 1057
Query: 1866 EGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV---------IAVNDYGFGTPSSPSQ 1916
+G + + + SSYT D L+P Y+ + +AV G G P
Sbjct: 1058 KGGASLSPQYVSYNQSSYT-QWD-LQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLP-- 1113
Query: 1917 SVPAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALG 1976
PA F E WF+ ++ + L+ ++LL+ I R + KY+ K S A
Sbjct: 1114 --PA----GFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEA-- 1165
Query: 1977 HSEMMSLDESSFPALELNNRRLSVKNSFCRKNG 2009
M + +LE +N + +S NG
Sbjct: 1166 -RPMKDETFGEYRSLESDNEEKAFGSSQPSLNG 1197
Score = 146 bits (369), Expect = 2e-34
Identities = 246/1090 (22%), Positives = 416/1090 (38%), Gaps = 117/1090 (10%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITL-----ENTLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
P+ Q W RDG P + +T+ + I + A R+ Q + NK
Sbjct: 63 PEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRF--QGIYRCFASNKL 120
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIK-LHIIWKKD 254
++ + + A P P + P V G S V L C N P + L I W
Sbjct: 121 GTAMSHEIRLMAEGA-PKWPKETVKP--VEVEEGES-VVLPC--NPPPSAEPLRIYWMNS 174
Query: 255 GVLL----SGGISDHNRRLTIPNPTGSDA-GYYECEA-------VLRSSSVPSVVRGAYL 302
+L N L N SD Y C A +++ + V+
Sbjct: 175 KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNS 234
Query: 303 SVLEPPQ--FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
+ P+ F H+ A + + + C A+G P P+I W + + + +++T Q
Sbjct: 235 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY--QN 292
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
++ LQ+ + +D G ++C A N+ G + + Y+ V + AP P G +
Sbjct: 293 HNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA-APYWLHKPQSHLYGPGETAR 351
Query: 421 LACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATN 479
L C+ G P+P +TW+ G + Q R ++ G+L++S SD C A N
Sbjct: 352 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYR---IQRGALILSNVQPSDTMVTQCEARN 408
Query: 480 SRGVDEASADL-VVWARTRI-TKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
G+ A+A + VV +I T Q ++G+ A ++C P +++++ ++DG T
Sbjct: 409 RHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTT 467
Query: 538 LGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
+ + R NG+L I + D G Y C + N + A+L+V+ + P
Sbjct: 468 VLQDE--RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP- 524
Query: 598 ATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVP 657
ST+E++ +T+T + L I + L + G +
Sbjct: 525 --RSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFIEDGRLV 577
Query: 658 ARSYQFRLCAVNDVGKGQFSKDTE------RVSLPEEPPTAPPQNVIASGR---TNQSIM 708
S + +D G TE R L P ++ S T +
Sbjct: 578 IHSLDY-----SDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVR 632
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVG--YQFKNITDADVNNLLLEDLIIWTNYEIE 766
+ W P E H N ++ Y I + + Y + + L L + +Y
Sbjct: 633 VSWSPA-EDH-NAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL--KLSPYVHYTFR 688
Query: 767 VAAYNSAGLGVYSS-KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTW--------NAPSP 817
V A N G G S T T + P P +V E +T + TW NAP
Sbjct: 689 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQV 748
Query: 818 QFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF--VSGLKKFTEYFTSVLCFT 875
Q+ + W P+ T P + + F VS F Y V
Sbjct: 749 QY---------RVQWRPQG-------TRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVN 792
Query: 876 TPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS-LKVSWQ--EPGEKNGILTGYRIS- 931
+ G GP + + ED P + L EIL++S + V W+ + + G L GY ++
Sbjct: 793 SQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTY 852
Query: 932 WEEYNRTNTRVTHY------LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
W E ++ H +P T ++GL ++Y +EV A +G G S T S
Sbjct: 853 WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFS 912
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIH 1045
+ P +PG P L + S+ L+++P ++ +++ + EG + L
Sbjct: 913 T--PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH--PLDEGGKGQLSF 968
Query: 1046 QLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSL 1105
L +P+ R+ + DL+P Y F+++ G L D N+S
Sbjct: 969 NL-RDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF--GNIS- 1024
Query: 1106 RTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDL 1165
TA E + W+P E + N + K + G +LS + YT DL
Sbjct: 1025 ATAGENYSVVSWVP-KEGQCNFRFHIL---FKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
Query: 1166 EEWTEYRVQV 1175
+ T+Y + +
Sbjct: 1081 QPDTDYEIHL 1090
Score = 145 bits (367), Expect = 3e-34
Identities = 127/495 (25%), Positives = 213/495 (43%), Gaps = 27/495 (5%)
Query: 993 PGPPTNLGISNIG---PRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
PGP L +S++ V + + P D I ++ +E + + E+W + L
Sbjct: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP-EKW---YSLGK 667
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
P ++ L+P+ Y+FR+ +N G PS S + T +A P+ P +V
Sbjct: 668 VPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 727
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
T++ + W PL M++N V Y++++ G +V D + + +
Sbjct: 728 TTNMVITWKPLRWMDWNA--PQVQYRVQWRPQGTRGPWQEQIVSDPF---LVVSNTSTFV 782
Query: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRN 1229
Y ++VQA N+ G GP Q +G + E P + P SS++LV+W V A
Sbjct: 783 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 842
Query: 1230 GLVLGYKVMYKEKDSDTQ------PRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
G + GY V Y + S + + +V ++ S L+GL Y Y ++V AF G
Sbjct: 843 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 902
Query: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQIT-HRLNT 1342
G S T + VPG P + TS+ L WQPP + NG++ Y ++ H L+
Sbjct: 903 SGPASE--FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
Query: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402
+ + P R + T L P Y F++ A T++G GEA T
Sbjct: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
Query: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTI-QTRELPSGRWALHSASVSHNASSF 1461
+ E+ ++SW P +G R++ + + G +L VS+N SS+
Sbjct: 1021 GNISATAGENYS----VVSWVP-KEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSY 1075
Query: 1462 IVDRLKPFTSYKFRV 1476
L+P T Y+ +
Sbjct: 1076 TQWDLQPDTDYEIHL 1090
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 246 bits (629), Expect = 1e-64
Identities = 395/1726 (22%), Positives = 665/1726 (38%), Gaps = 198/1726 (11%)
Query: 147 WFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
W ++G ++P +R++ ++ + L I PD G Y V A DK S L +
Sbjct: 12766 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDK------SVAELLII 12819
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS 263
E APT + V + C + K ++ W ++G + G
Sbjct: 12820 E---------APTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKK 12867
Query: 264 ------DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE-PER 316
RL I + D Y C R S V + ++ PPQ + E P
Sbjct: 12868 YKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGA 12927
Query: 317 HIT--AEMEKVVDIPCQAKGVPPPSITWYKD-AAVVEVEKLTRFRQRNDGGLQISGLVPD 373
+ AE+ K + W ++ VV+ +K + LQI + P
Sbjct: 12928 DVVFLAELNK-----------DKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR 12976
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D G ++ A++ E + LA AP I D V G + + P+
Sbjct: 12977 DQGEYRFIAKDK--EARAKLELAA---APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEA 13031
Query: 434 TWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW 493
W K L++ ++ T E S I D G Y + N G E +L V
Sbjct: 13032 EWFKENEPLSTKTID----TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV- 13086
Query: 494 ARTRITKPPQDQSVIKGTQASMVCG----VTHDPRVTIRYIWEKDGATLGTESHPRIRLD 549
+ P ++ V + + +T I Y+ E+ T + D
Sbjct: 13087 --IDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV---LATD 13141
Query: 550 RNGSLHISQTWSGDIGT-YTCRV-----ISAGGNDSRSAHLRVRQLPHAPEHPV-ATLST 602
R S + T G Y RV + G + R P P+ T++
Sbjct: 13142 RAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITD 13201
Query: 603 VERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSY 661
V R ++LTW P +DG + + Y++E+ + + +V + S TV +V + Y
Sbjct: 13202 VNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEY 13261
Query: 662 QFRLCAVNDVGKGQFSKDTE--RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
FR+ A N +G G+ S T +V+ P E P+ PP N+ +S +T S+ ++W+PP +
Sbjct: 13262 SFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSSVQLKWEPPLKDGG 13320
Query: 720 NGILKGYIIRYCLAGLP--VGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
+ IL GYII C G + K + + LE Y V+A N AG+
Sbjct: 13321 SPIL-GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK---GNKYLYRVSAENKAGVSD 13376
Query: 778 YSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837
S + T P ++ A I P+P I + GY
Sbjct: 13377 PSEILGPLTADDAFVEPTMDLSAFKDGLEVI-----VPNPITILVPSTGYP--------- 13422
Query: 838 EEVTMVTARPNFQDSI-HVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG 896
TA F D + G +K + Y V+ + D T +L + + G
Sbjct: 13423 ----RPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 13478
Query: 897 PVG-----------HLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR-TNTRVT 943
+ L F +I S+ ++W+ P + G LTGY + E +R T T+V
Sbjct: 13479 EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVM 13538
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA--STISSGVPPELPGPPTNLGI 1001
++ + LE+ V L Y +V A G G+ + ++ P +P PP N+
Sbjct: 13539 DFVTD--LEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKW 13596
Query: 1002 SNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS-MEVP 1059
+ S+ L + P DG + I ++VE ++W+ EP A + MEV
Sbjct: 13597 RDRTANSIFLTWDPPKNDGGSRIKGYIVER---CPRGSDKWVAC----GEPVAETKMEVT 13649
Query: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTL--QAPPDM-----APANVSLRTASETS 1112
L Y++R++ +N G S PS+P+ +IQ + Q P++ A ++++ ++
Sbjct: 13650 GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIE 13709
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER--DYTIEDLEEWTE 1170
L G PE KI ++++D K + + V + TI D +
Sbjct: 13710 L--------PATVTGKPEP---KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 13758
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
++A N G T V P T+ S L+ W+ P D
Sbjct: 13759 GTYIIEAVNVCGRA----TAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP-PRDDGGS 13813
Query: 1231 LVLGYKVMYKEKDSDTQPRF-WLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-S 1288
+ Y V + DS+ + V+ + ++ +L +Y+ +V A G G P
Sbjct: 13814 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF---RVAAENMYGVGEPVQ 13870
Query: 1289 HPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTA 1348
PI + D PGPP + ++ +V L W P G + RL+ T
Sbjct: 13871 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 13930
Query: 1349 TVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRP 1406
+ Y GL + Y FR+ A+ G G+ +++ ++ + D P PP +P
Sbjct: 13931 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKP 13990
Query: 1407 MVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDR 1465
V +DV SV L+W +P DG + + Y I+ + + W + V + ++
Sbjct: 13991 TV--KDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVP--TTQHLLPG 14046
Query: 1466 LKPFTSYKFRVKATNDIGDSEFSEESES-LTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
L Y FRV+A N G+SE SE S+ L + P P L V T + ++W
Sbjct: 14047 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 14106
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
P +D + + + R++ +G W + + + LT+
Sbjct: 14107 PEKDG-GSPITNYIVEKRDVRRKG---------------WQTVDTTVKDTKCTVTPLTEG 14150
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT--AAPRNVVVHGATATQLDV 1642
L Y R++ NA+G+ + ++ + + T P + V T +D+
Sbjct: 14151 SL--------YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 14202
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
WEPP D IQ Y I E + KT + + ++ ++ T V A
Sbjct: 14203 KWEPPKNDG-GRPIQRYVIEKKERLGTRWVKAGKTAG-PDCNFRVTDVIEGTEVQFQVRA 14260
Query: 1703 FNAAGDGPRSTPTQ---GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
N AG G S PT+ + + PS P + ++ + ++W+ P+ G + GY
Sbjct: 14261 ENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYH 14320
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD-LAEGVTYRFRIRA 1803
+ E C PV G K + V+ + L KV++ + Y R+RA
Sbjct: 14321 V--EMC-PV-GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 14362
Score = 225 bits (573), Expect = 4e-58
Identities = 433/1960 (22%), Positives = 731/1960 (37%), Gaps = 276/1960 (14%)
Query: 72 LEYRYMITSLDRTHAGFYRCIVRNRMGAL---------LQRQTEVQVAYMGSFEEGEKHQ 122
+E ++ ++ L +R I +N GA+ + + EV++ + +
Sbjct: 23576 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 23635
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTLVILSTVAPDAG 179
V+ GE + A + P P + W R ++I S+R I + L++ + D G
Sbjct: 23636 VVNAGETFRLEAD-VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 23694
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVA 239
+Y ++A N S P+ + V + GP P V TSE
Sbjct: 23695 QYILRA---SNVAGSKSFPVNVKVLDRPGP----------PEGPVQVTGVTSE------- 23734
Query: 240 NARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAG-YYECEAVLRSSSVPSVVR 298
K + W L G SD + + T A E V S V ++
Sbjct: 23735 ------KCSLTWSPP---LQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLE 23785
Query: 299 G---AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV------ 349
G + + V EP M+ +P K + +I KD+ V
Sbjct: 23786 GNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIA--KDSMTVCWNRPD 23843
Query: 350 ----------EVEKLTRF---------RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQ 390
VEK R R+ D L+++GL D F+ A NAAG +
Sbjct: 23844 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 23903
Query: 391 TS-TYLAVTSIAPNITRGP------LDST-----------VIDGMSVVLA-----CETSG 427
S + + P GP +D+T + DG S +L C+
Sbjct: 23904 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 23963
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA- 486
+T Q G R+ T E L T + C A N G+ EA
Sbjct: 23964 EEWQIVTPQTGLRV-----------TRFEISKL----TEHQEYKIRVC-ALNKVGLGEAT 24007
Query: 487 SADLVVWARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
S V ++ P D + ++ S + R T W ++
Sbjct: 24008 SVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---- 24063
Query: 541 ESHPRIRLDRNGS---LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
E ++++++ + L I D G Y ++ ++ G+ S ++V P P++
Sbjct: 24064 EFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-- 24121
Query: 598 ATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLV 656
+ V + + L W P DG + + Y+++ E+ ++S K TS V+ L
Sbjct: 24122 LAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLT 24180
Query: 657 PARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPE 716
Y FR+ A N+ G G + + V E P +PP V + + S + W+ P
Sbjct: 24181 EGAIYYFRVMAENEFGVGVPVETVDAVKAAE--PPSPPGKVTLTDVSQTSASLMWEKPEH 24238
Query: 717 SHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG 776
+ +L GY++ G ++ + ++ V N ++ L Y+ V AYN G
Sbjct: 24239 DGGSRVL-GYVVEMQPKGTE---KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKG-- 24292
Query: 777 VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF-------INGINQGYKL 829
++ + GVP + + T +++ +N S Q I I +
Sbjct: 24293 -----KSDPRVLGVPVIA-----KDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 24342
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
I+W ++ E T R N +++ V +K+ + T +T L
Sbjct: 24343 ISW--VKDGEPLKQTTRVNVEETA-TSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 24399
Query: 890 THEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLP 947
+ PG PVG + F E+ + +SW+ P G ++ Y + R T T ++
Sbjct: 24400 IVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMV 24455
Query: 948 NVTL---EYRVTGLTALTTYTIEVAAMTSKGQ-GQVSASTISSGVPPELPGPPTNLGISN 1003
+ T+ ++T L T Y + A G+ + + + P + PGPP +++
Sbjct: 24456 SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTS 24515
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I + +Q+ P DG T I + +E + E L + + L+
Sbjct: 24516 ISKDQMLVQWHEPVNDGGTKIIGYHLEQK-----EKNSILWVKLNKTPIQDTKFKTTGLD 24570
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPE 1122
Y F++ NIVG PS+ S + P P + ++ L+W +
Sbjct: 24571 EGLEYEFKVSAENIVGIGKPSKVSECF--VARDPCDPPGRPEAIVITRNNVTLKW---KK 24625
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G + GY ++ + G+ + + +E ++T+ L E Y +V A NA G
Sbjct: 24626 PAYDGGSKITGYIVE-KKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 24684
Query: 1183 --SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE--VPEADRNGLVLGYKVM 1238
S P + R+ + + N S ++V E V EAD G + V
Sbjct: 24685 NFSEPSDSSGAITARDEIDA---PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 24741
Query: 1239 YKE-KDSDTQPRFWLVEGNSSRSAQL------TGLGKYVLYEVQVLAFTRIGDGSPSHPP 1291
K+ K+ + ++ ++ + T G+Y+L V G P
Sbjct: 24742 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNV--------GGTKSIP 24793
Query: 1292 ILERTLDDVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATV 1350
I + LD PGPP G L V L W PP G +++ I + T+ + V
Sbjct: 24794 ITVKVLDR-PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 24852
Query: 1351 EVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTT-EKRDRPQPPSRPMVQ 1409
A Y T L P + Y+FR+ A + G GE E+ VT P PPS P V
Sbjct: 24853 ST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVS 24911
Query: 1410 QEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKP 1468
+ S++++W P DG + + Y ++ R+ RW + + V L
Sbjct: 24912 A--ITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDL-RLRVTGLTE 24968
Query: 1469 FTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAE 1527
SY+FRV A N G E SE S A P P+ VT + +SV + W P
Sbjct: 24969 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKP-- 25026
Query: 1528 DKINGILLGFRIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
+Y+G ++G+ + W T ++ Q+
Sbjct: 25027 -----------------IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG------KQF 25063
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAVP------TAAPRNVVVHGATA 1637
+ L ++ Y R+ N+ G G P++ P V E + A R VVV A+A
Sbjct: 25064 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 25123
Query: 1638 T-QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE-NSVKLKNLTGYTA 1695
T +L VT + P WE G LT+R + + + + N+T + +
Sbjct: 25124 TLRLFVTIKGRPEPEVK----------WEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDS 25173
Query: 1696 YMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILE 1755
++ N +G T +PSAP ++ E+ SV +SWE P G
Sbjct: 25174 GRYNLTLENNSGS---KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGA-- 25228
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN 1815
++ + K + ++++L EG +Y FR+ A YG + A
Sbjct: 25229 --KITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASN-EYGIGLPAE 25285
Query: 1816 VTTGPGEGA--PGPPG-VPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDI 1871
TT P + + P PPG V ++ + I W + G IT YV+E + W
Sbjct: 25286 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 25344
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
+V + ++ L G Y FRV AVN+ G P
Sbjct: 25345 C-----TQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDP 25379
Score = 218 bits (556), Expect = 4e-56
Identities = 418/1900 (22%), Positives = 731/1900 (38%), Gaps = 252/1900 (13%)
Query: 136 RIASFPQPQVTWFRDGRKIPPS----------SRIAITLENTLVILSTVAPDAGRYYVQA 185
+I P P +TWF+ K P + +++ + TLVI + D G Y + A
Sbjct: 16139 KIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITA 16198
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTII------------IPPKNTSVVAGTSEV 233
VN+ +K + + +G P P+ P PPK+ T+ V
Sbjct: 16199 VNNLGTASKE-----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 16253
Query: 234 TLECVANARPLIKLHIIWKKDGVLLSGGISDHNR--RLTIPNPTG-SDAGYYECEAVLRS 290
+ AN + + + K+ + + H R+ N G + E E
Sbjct: 16254 IEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 16313
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY--KDAAV 348
SVP + P +T E+ + G P + W KD
Sbjct: 16314 FSVPGAP--------DKPTVSSVTRNSMTVNWEEP-----EYDGGSPVTGYWLEMKDTTS 16360
Query: 349 VEVEKLTR--FRQRNDG-GLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIA 401
+++ R + G +++GL+ F+ +A NAAG + + A IA
Sbjct: 16361 KRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 16420
Query: 402 P---------NITRGPLD----STVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQ 448
P + T+ D + DG S V W+KG+ G+
Sbjct: 16421 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 16480
Query: 449 LPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE-ASADLVVWARTRITKPP----- 502
+ T L+ G+ + A N G+ E V+ + R+ P
Sbjct: 16481 V--VTGLKEGAFY----------KFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 16528
Query: 503 --QDQSVIK-GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
+D+ V+ G ++ V+ P T+ W + TL E+ + S+ I
Sbjct: 16529 SVRDRIVVHAGGVIRIIAYVSGKPPPTVT--WNMNERTLPQEATIETTAI-SSSMVIKNC 16585
Query: 560 WSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-G 618
G Y+ + G ++ + V +P P + + LTW P D G
Sbjct: 16586 QRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA-HNLTNESCKLTWFSPEDDG 16644
Query: 619 NSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS 677
SP+ Y++E E++ WT + +V + + TV+GL+ ++Y FR+ A N +G G F
Sbjct: 16645 GSPITNYVIEKRESDRRAWTPVTYTVTRQ--NATVQGLIQGKAYFFRIAAENSIGMGPFV 16702
Query: 678 KDTERVSLPEEPPTAP--PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGL 735
+ +E + + EP T P P+++ T ++ + W PP + G II Y L
Sbjct: 16703 ETSEALVI-REPITVPERPEDLEVKEVTKNTVTLTWNPP--KYDGG---SEIINYVLESR 16756
Query: 736 PVGYQ-FKNITDADV--NNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPT 792
+G + F +T+ ++ ++ L YE V+A N G G S T +
Sbjct: 16757 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKD--E 16814
Query: 793 VPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQ----EEEVTMVTARPN 848
+ P +H + + TIR +G + ++W ++ E++ T + P
Sbjct: 16815 LAPPTLHLDFRDKLTIRVGEAFALTGRYSG--KPKPKVSWFKDEADVLEDDRTHIKTTPA 16872
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILD 908
++ + + + + + V+ +T G R V + PVG +SF E+
Sbjct: 16873 ---TLALEKIKAKRSDSGKYCVVVENST---GSRKGFCQVNVVDRPGPPVGPVSFDEVTK 16926
Query: 909 TSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVTLEYRVTGLTALTTYTI 966
+ +SW+ P + G +T Y I +E + VT T +V+ L Y
Sbjct: 16927 DYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC--KVSKLLEGKDYIF 16984
Query: 967 EVAAMTSKGQGQVSASTISSGVPPE----LPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
+ A G +S +S + + +P P ++ + S + + +DG
Sbjct: 16985 RIHAENLYG---ISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKP 17041
Query: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
I+ +++E + + + W + + P + VPDL Y FR+ N +G P
Sbjct: 17042 ITNYILEKRETM---SKRWARVTKDPIHPYTK-FRVPDLLEGCQYEFRVSAENEIGIGDP 17097
Query: 1083 SQPSRKIQTLQ--APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR 1140
S PS+ + A P P N + S+ L W P ++G + +GY ++Y +
Sbjct: 17098 SPPSKPVFAKDPIAKPS-PPVNPEAIDTTCNSVDLTWQP---PRHDGGSKILGYIVEYQK 17153
Query: 1141 -SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRE 1196
D + +H + E Y + L + Y+ +V A NA G + + V+ + R
Sbjct: 17154 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 17213
Query: 1197 SVPS-------SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD--TQ 1247
P + ++ T S +++ P KV +K++D D T+
Sbjct: 17214 EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP-----------KVTWKKEDRDAPTK 17262
Query: 1248 PRFWLVEGNSS---RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1304
R + S R+A G Y L + + + S ++ + D PGPP
Sbjct: 17263 ARIDVTPVGSKLEIRNAAHEDGGIYSL---------TVENPAGSKTVSVKVLVLDKPGPP 17313
Query: 1305 MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
+ E+R S L W+ P G ++ + R + +A + + + + + A
Sbjct: 17314 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK-KSHFAKH 17372
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSW- 1422
L + YLFR+ A+ + G G E + D PP P + DV V L W
Sbjct: 17373 LNEGNQYLFRVAAENQYGRGPFVET-PKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 17431
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
+P DG SP+ Y ++ +E + W + +V L+ +Y+FRVKA N +
Sbjct: 17432 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC---VVTGLQQGKTYRFRVKAENIV 17488
Query: 1483 GDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK----INGILL--G 1536
G PD + P L+ PP+ + I G+++ G
Sbjct: 17489 G--------------LGLPD------TTIPIECQEKLV---PPSVELDVKLIEGLVVKAG 17525
Query: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWA------ELTSMYSMRNLSRPSLTQYELDNLN 1590
+R+ ++ RG+ P A W + Y++ + S+ + N
Sbjct: 17526 TTVRFPAII---------RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT--IKNCL 17574
Query: 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+ E +++V NA G + V PT P N++ T + ++W+PP D
Sbjct: 17575 RRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINIL--DVTPEHMTISWQPPK-D 17630
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
+ Y + + ++ T V + ++ +K+ +L Y+ V A N G GP
Sbjct: 17631 DGGSPVINYIVEKQDTRKD--TWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGP 17688
Query: 1711 R--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPV 1767
STPT + + + PS P +++T + VSW P+ G + GY Y V
Sbjct: 17689 PLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGY---YMERREV 17745
Query: 1768 DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTTGPGEG 1823
G K V V+ + L +V L EG TY FR+ A+ P + P +
Sbjct: 17746 TG--KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK- 17802
Query: 1824 APGPPGVPIIVRYSSAIA-IHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
PGPP P + S A + W+ G PI YV+E + W+ + KD + +
Sbjct: 17803 PPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD--ELIR 17860
Query: 1882 SYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
F + L G Y FR+ A N G G P ++SV A+
Sbjct: 17861 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAK 17900
Score = 215 bits (548), Expect = 3e-55
Identities = 424/1882 (22%), Positives = 697/1882 (37%), Gaps = 278/1882 (14%)
Query: 378 FQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMSVVLACETSGAP 429
F+ A+N AG E +S + I P + + +I G + SG P
Sbjct: 28616 FRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRP 28675
Query: 430 RPAITWQKGE-RILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASA 488
P +TW+ E R+ + V + T + +L + + D+G Y N+ GV S
Sbjct: 28676 APKVTWKLEEMRLKETDRVSIT--TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV 28733
Query: 489 DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--IRYIWEK--DGATLGTESHP 544
+VV R P + S + + G D T YI EK G T +
Sbjct: 28734 TVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNS 28793
Query: 545 RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLST-- 602
++ + H+++ Y+ RV S + + P EHP S
Sbjct: 28794 SVKRTQIKVTHLTKYME-----YSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPT 28845
Query: 603 ------VERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGL 655
V A+++ W +P+ DG S +I Y +E E N V V + V GL
Sbjct: 28846 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 28905
Query: 656 VPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPP 715
V YQFR A+N G + S + R + + P AP + + T ++ + W P
Sbjct: 28906 VEGLEYQFRTYALNAAGVSKAS-EASRPIMAQNPVDAPGRPEVTDV-TRSTVSLIWSAPA 28963
Query: 716 ESHQNGILKGYII-RYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSA 773
+ ++ GYII R ++ + G K N T N + L YE V A N+A
Sbjct: 28964 YDGGSKVV-GYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAA 29022
Query: 774 GLGVYSSKVTEWTLQGVPTVPP-----GNVHAEATNSTTIRFTWNAPSPQFINGINQGYK 828
G+ S+ T PP +H + TIR + + G + K
Sbjct: 29023 GVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV---TIRAGSDLVLDAAVGGKPEP-K 29078
Query: 829 LIAWEPEQE----EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRST 884
+I + ++E E+V++ I S K+T + G ++
Sbjct: 29079 IIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA-------SGTKAV 29131
Query: 885 PQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVT 943
+V+ D PGP G L+ S + ++W P E G +T Y + E +R N +
Sbjct: 29132 SVMVKVL-DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 29190
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG-QVSASTI---SSGVPPELPGPPTNL 999
TL Y VT L Y V A+ G G V + I +S P PG P +
Sbjct: 29191 EG-ECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEV 29249
Query: 1000 GISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEV 1058
G G + +Q+ +P DG IS +LV+ + + W +++ D R ++V
Sbjct: 29250 GT---GKEHIIIQWTKPESDGGNEISNYLVDKREK---KSLRWTRVNKDYVVYDTR-LKV 29302
Query: 1059 PDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP----PDMAPANVSLRTASETSLW 1114
L Y FR+ VN G S PS+ S I + P AP V S + W
Sbjct: 29303 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 29362
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
+ M Y+G + VGY ++ D H ++T+ DL+ +Y +
Sbjct: 29363 TKPM------YDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFR 29416
Query: 1175 VQAFNAIGSGPWSQTVVGRT---RESVPSSGPTN-----VSALATTSSSMLVRWSEVPEA 1226
V A N G +S+++ R +P + V+ A S ++V S P
Sbjct: 29417 VAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP 29476
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
+ + ++ D R + +++ S L + K Y+
Sbjct: 29477 ---------VITWSKQGIDLASRAII---DTTESYSLLIVDKVNRYDAGKYTIEAENQSG 29524
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+L + D PGP + EV SV + W+ P G + I +
Sbjct: 29525 KKSATVLVKVYD-TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRA 29583
Query: 1347 TATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPS 1404
TV S Y +GL ++Y FR+ + G GE E V+ +E P P+
Sbjct: 29584 FKTVTTKC-SKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PLVPA 29639
Query: 1405 RPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
+ ++ DV +V L+WE P DG S + Y ++ + + RW + ++ V
Sbjct: 29640 K--LEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW-MKVVTLKPTVLEHTV 29696
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRW 1522
L Y FR++A N+ G SE E ++T PTI LS P T V
Sbjct: 29697 TSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRV--LPTIDLSTMPQKTIHV---- 29750
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLT 1582
PA + ++ + G P A+W S +R R ++
Sbjct: 29751 --PAGRPVELVI------------------PIAGRPPPAASWFFAGS--KLRESERVTVE 29788
Query: 1583 QYELDNLNKHRRYEIRMSVYNAVGE---------GPSSPPQEVFV-GEAVPTAAPRNVVV 1632
+ K + IR + GE G +S +V + + P P + +
Sbjct: 29789 TH-----TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP--IKI 29841
Query: 1633 HGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTG 1692
AT + ++WEPP LD + GY + +A R +++ ++ K LT
Sbjct: 29842 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTE 29898
Query: 1693 YTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Y+ VAA N G G +S + ++ P P +++ +++ + ++W P+
Sbjct: 29899 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 29958
Query: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
G V+ + + + W++V + +T R R+ T G
Sbjct: 29959 GG---------------SQVTGYIVERKEVRADRWVRVNKVPVTMT---RYRSTGLTEGL 30000
Query: 1811 EIEANVTT--GPGEGAPGPPGVPIIVR-----------------YSSAIAIHWS-SGDPG 1850
E E VT G G P P PI+ +++++ WS D G
Sbjct: 30001 EYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEG 30060
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
+T Y+IE + D+ W P ++ YT + L G Y FRV+A N G G
Sbjct: 30061 GSKVTGYLIEMQKVDQHEWT-KCNTTPTKIREYTLTH--LPQGAEYRFRVLACNAGGPGE 30117
Query: 1911 PSSPSQSV--------PAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAK 1962
P+ +V P + + Y+E F+ ++ L + I+G+ K
Sbjct: 30118 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRL--------TIPIKGKPFPICK 30169
Query: 1963 KTDSGNSAKSGAL-----GHSEMMSLD----ESSFPALELNNRRLSVKNSFCRKNGLYTR 2013
T G A+ H+E++ + +S L L N+ C K +Y +
Sbjct: 30170 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENK--------CGKKAVYIK 30221
Query: 2014 SPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSF 2073
SP S E +Y+D I S ++ +P +D G+D +
Sbjct: 30222 VRVIGSPN----SPEGPLEYDD-IQVRSVRVSWRPP--ADDGGADI---------LGYIL 30265
Query: 2074 VNHYISDPTYYNSWRRQQ------KGISRAQAYSYTESDSGEPDHTTVTNSTSTQQGSLF 2127
+ +Y R + KG+ Y + S + Q +
Sbjct: 30266 ERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVS--------------AENQFGIS 30311
Query: 2128 RPKASRTP----TPQNPPNPPS 2145
+P S P TP NPP PPS
Sbjct: 30312 KPLKSEEPVTPKTPLNPPEPPS 30333
Score = 213 bits (541), Expect = 2e-54
Identities = 413/1864 (22%), Positives = 693/1864 (37%), Gaps = 243/1864 (13%)
Query: 147 WFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
WFR+ I SS+ I ++ TL I D Y V N + + K++ + +
Sbjct: 12672 WFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEE 12731
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV------L 257
E++ I+ P K+ + S VT C N + + + W K+G
Sbjct: 12732 EDL---------RIVEPLKDIETMEKKS-VTFWCKVNR---LNVTLKWTKNGEEVPFDNR 12778
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP-QFVKEPER 316
+S + + LTI + D G Y ++ + SV A L ++E P +FV+ E
Sbjct: 12779 VSYRVDKYKHMLTIKDCGFPDEGEY----IVTAGQDKSV---AELLIIEAPTEFVEHLED 12831
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ---ISGLVPD 373
E + V CQ ++ WY++ E+++ +++ DG + I D
Sbjct: 12832 QTVTEFDDAV-FSCQLSR-EKANVKWYRNGR--EIKEGKKYKFEKDGSIHRLIIKDCRLD 12887
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D + C + + L V I I R P D G VV E + + +
Sbjct: 12888 DECEYACGVEDRKSRAR----LFVEEIPVEIIRPPQDILEAPGADVVFLAELN-KDKVEV 12942
Query: 434 TWQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAGTYTCLATNSRGVDEASADL 490
W + ++ G + + G L I D G Y +A + EA A L
Sbjct: 12943 QWLRNNMVVVQGD----KHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKL 12994
Query: 491 VVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR 550
+ A +I QD V G +MV V +D W K+ L T++
Sbjct: 12995 ELAAAPKIKTADQDLVVDVGKPLTMV--VPYDAYPKAEAEWFKENEPLSTKTIDTTA--E 13050
Query: 551 NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER--RAI 608
S I + GD G Y + + G +L+V +P PV L E +
Sbjct: 13051 QTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPG----PVRNLEVTETFDGEV 13106
Query: 609 NLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPAR-SYQFRLC 666
+L W +P DG S +I Y++E + T +LA+ ++ TV GL Y FR+
Sbjct: 13107 SLAWEEPLTDGGSKIIGYVVERRDIKRK-TWVLATDRAESCEFTVTGLQKGGVEYLFRVS 13165
Query: 667 AVNDVGKGQ-FSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKG 725
A N VG G+ D + + PP NV + + + W+ PPE +
Sbjct: 13166 ARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWE-PPEYDGGAEITN 13224
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
Y+I + + A+ + + D++ Y V A N G+G S T +
Sbjct: 13225 YVIE-LRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVG-KPSAATPF 13282
Query: 786 TLQGVP---TVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
P PP N+ + ++++ W P + G ++ + E+ EE
Sbjct: 13283 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK------DGGSPILGYIIERCEEGKD 13336
Query: 843 VTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHL 901
R N + + + V+GL+K +Y V G V ++ GP+
Sbjct: 13337 NWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG---------VSDPSEILGPL--T 13385
Query: 902 SFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLE----YRVTG 957
+ ++ ++ +S + G + + I T + LE ++
Sbjct: 13386 ADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKT 13445
Query: 958 LTALTTYTIEVAAMTSKG----QGQVSASTISSGVPPEL---PGPPTNLGISNIGPRSVT 1010
L+A I + + KG + + TIS + + P P L +I SV
Sbjct: 13446 LSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVH 13505
Query: 1011 LQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSF 1069
L + P DG + ++ ++VE + + W + + + VPDL Y F
Sbjct: 13506 LTWEPPDDDGGSPLTGYVVEKR---EVSRKTWTKVMDFVTDLE---FTVPDLVQGKEYLF 13559
Query: 1070 RMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
++ N G P+ + T PD P NV R + S++L W P + +G
Sbjct: 13560 KVCARNKCGPGEPAYVDEPVNMSTPATVPD-PPENVKWRDRTANSIFLTWDP---PKNDG 13615
Query: 1128 NPESVGYKIKY--SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
GY ++ SD V + ++E + LEE Y +V+A N G
Sbjct: 13616 GSRIKGYIVERCPRGSDKWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASK 13671
Query: 1183 -SGPWSQTVVGRTRE--------------SVPSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
S P + T+E +V + + A T + W++
Sbjct: 13672 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKA---- 13727
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++L ++ + +V+ S + G Y++ V V
Sbjct: 13728 --DMILKQDKRITIENVPKKSTVTIVDSKRSDT------GTYIIEAVNVCG--------- 13770
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILA----------YQIT 1337
++E + D PGPP +V S L W PP G + ++
Sbjct: 13771 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 13830
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKR 1397
H+L++T +T + AT L P Y+FR+ A+ G GE +A +T + +
Sbjct: 13831 HKLSSTVKDT-----------NFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ 13879
Query: 1398 -DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
D P PP+R ++ D+ +V L+W EP DG SP+ Y ++ + + +W + +
Sbjct: 13880 FDPPGPPTR--LEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW-VRCNKMP 13936
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVT 1511
+++ V L Y+FRV A N G + S+ +E + P PT+ V
Sbjct: 13937 VKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDV- 13995
Query: 1512 PHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMY 1571
TSV + W P D G +I + + + W
Sbjct: 13996 --GKTSVRLNWTKPEHDG------GAKI----------ESYVIEMLKTGTDEW------- 14030
Query: 1572 SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAV-PTAAPRN 1629
+R TQ+ L L + + Y R+ N GE PS P V E + P + PR
Sbjct: 14031 -VRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRW 14089
Query: 1630 VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKN 1689
+ V T D+ W P D I Y + + +R + V T + + +
Sbjct: 14090 LEVINITKNTADLKWTVPEKDG-GSPITNYIVEKRDVRRKG-WQTVDTT-VKDTKCTVTP 14146
Query: 1690 LTGYTAYMVSVAAFNAAGDGPRS---TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEA 1746
LT + Y+ VAA NA G + + P P ++ ++T V++ WE
Sbjct: 14147 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEP 14206
Query: 1747 PQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTF 1806
P+ G R V E + ++ V +V D+ EG +F++RA+
Sbjct: 14207 PKNDGG-RPIQRYVIEKKERLG--TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENE 14263
Query: 1807 TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA----IAIHWSSGDP-GKGPITRYVIEA 1861
E PP P+ + + A IAI W + G PI Y +E
Sbjct: 14264 AGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM 14323
Query: 1862 RPSDEGLWDIL----IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
P W + IKD+ +V + + P Y RV AVN G PS S++
Sbjct: 14324 CPVGTEKWMRVNSRPIKDLKFKVE------EGVVPDKEYVLRVRAVNAIGVSEPSEISEN 14377
Query: 1918 VPAQ 1921
V A+
Sbjct: 14378 VVAK 14381
Score = 213 bits (541), Expect = 2e-54
Identities = 357/1619 (22%), Positives = 619/1619 (38%), Gaps = 152/1619 (9%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQ--TSTYLAVTSI----APNITRGPLDSTVI---DGM 417
+SGLV D F+ ARNAAG + + A+T+ APN + P VI G
Sbjct: 24664 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGE 24723
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ VL + G P P + W K + L + ++ + ++ +L++ +D G Y
Sbjct: 24724 TFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 24783
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT------IRYIW 531
+N G + V R PP+ + G A C + +P + YI
Sbjct: 24784 SNVGGTKSIPITVKVLDRPG---PPEGPLKVTGVTAEK-CYLAWNPPLQDGGANISHYII 24839
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAHLRVR 587
EK + + + + +L+ T Y RV++ G S +
Sbjct: 24840 EKRETSRLSWTQVSTEVQ---ALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC 24896
Query: 588 QLPHAPEHPVAT--LSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVD 644
P+ P P +T +S + + ++ +TW +P D G + + YILE +
Sbjct: 24897 N-PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT 24955
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQNVIASGRT 703
+ V GL SY+FR+ A N G G+ S+ + + P PP N + +
Sbjct: 24956 LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 25015
Query: 704 NQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGL--------PVGYQFKNITDADVNNLLL 754
S+ + W P + G +KGY++ A P G Q K T +
Sbjct: 25016 RSSVSLAWSKP--IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN-- 25071
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
T Y + A NS G+G ++ Q + P + +A + +A
Sbjct: 25072 ------TEYNFRICAINSEGVGEPATLPGSVVAQ--ERIEPPEIELDADLRKVVVLRASA 25123
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
F+ + + WE + E + A+ S + + + +F ++
Sbjct: 25124 TLRLFVTIKGRPEPEVKWE--KAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 25181
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G ++ VR + PV +L+ E+ S+ +SW+ P G +T Y +
Sbjct: 25182 NNSGS--KTAFVNVRVLDSPSAPV-NLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 25238
Query: 934 EYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R +T+ T +R+ L +Y V A G G + A T E
Sbjct: 25239 ETTRKAYATITNNCTKTT--FRIENLQEGCSYYFRVLASNEYGIG-LPAETTEPVKVSEP 25295
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
P PP + + ++ + T+++ +P DG + I+ ++VE Q E+W Q+
Sbjct: 25296 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKT-- 25350
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTAS 1109
+ L Y FR+ VN G S P Q + + ++ P + + +
Sbjct: 25351 --LEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKA 25408
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
L + ++ + G P++ + + + G+TL + V T+ L
Sbjct: 25409 REQLKI------DVPFKGRPQAT---VNWRKD---GQTLKETTRVNVSSSKTVTSLSIKE 25456
Query: 1170 EYRVQVQAF-----NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVP 1224
+ V + N+ GS T++ R P GP + ++ S+ + W+ P
Sbjct: 25457 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP--GPIRIDEVSC--DSITISWNP-P 25511
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV--EGNSSRSAQLTGLGKYVLYEVQVLAFTRI 1282
E D + Y V KE S T W + + + S ++ L Y+ +V A R
Sbjct: 25512 EYDGGCQISNYIVEKKETTSTT----WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 25567
Query: 1283 GDGSPSHPP-ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL 1340
G S S ++ PGPP +++ + WQ P G ++ Y + ++
Sbjct: 25568 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 25627
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + ++L Q +GL +Y +R+ A+ G G+ +++ RD
Sbjct: 25628 RSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPC 25685
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP +P V ++ +SV L W +P DG + + Y ++ RELP GRW L + +
Sbjct: 25686 DPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW-LKCNYTNIQET 25742
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
F V L Y+FRV A N SE SES + D P + + ++
Sbjct: 25743 YFEVTELTEDQRYEFRVFARN--AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIV 25800
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
++ KIN + G R ++ G + + ++ ++++ R
Sbjct: 25801 VKAGEVL--KINADIAG---RPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRR 25855
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1639
QY L N + ++ GP + P E+ +G TA +
Sbjct: 25856 DTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEI----------------NGLTAEK 25899
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
++W P D DI Y + + + +L + L S K+ L Y+
Sbjct: 25900 CSLSWGRPQEDG-GADIDYYIVE--KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFR 25956
Query: 1700 VAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEG 1756
V N G G S + PS P+S++ + +T S+ + W P+ G + G
Sbjct: 25957 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 26016
Query: 1757 YRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT---FTYGPEIE 1813
Y + + + + V V+ K L +K L EG Y +R+ A+ + E
Sbjct: 26017 YIIERREKNSL----RWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETS 26072
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDI 1871
+ P PP P IV + I I W G PIT Y +E + SD+ W
Sbjct: 26073 PLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKT 26132
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS--QSVPAQKANPFYE 1928
I+ + + YT S L G Y FRV +VN G PS S Q ++ P ++
Sbjct: 26133 SIQSL--RGTEYTISG--LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD 26187
Score = 211 bits (538), Expect = 5e-54
Identities = 373/1635 (22%), Positives = 612/1635 (37%), Gaps = 185/1635 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQ-----TSTYLAVTSIAPNITRGPLDS---- 411
+D ++ L DT F+ A+NAAG + T AP + LD+
Sbjct: 28997 SDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAP--PKAELDARLHG 29054
Query: 412 ---TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHIS 468
T+ G +VL G P P I W KG++ L ++T + + +I S
Sbjct: 29055 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG-KRATAVIKFCDRS 29113
Query: 469 DAGTYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGT--QASMVCGVT 520
D+G YT N+ G S + V + +++ Q++ + + Q +T
Sbjct: 29114 DSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEIT 29173
Query: 521 H---DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG-- 575
H + R T R W T S+ RL +N Y RV +
Sbjct: 29174 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNE-------------YIFRVRAVNKY 29220
Query: 576 --GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEM 629
G S + R +P P P + E I + WTKP DG + + Y+++
Sbjct: 29221 GPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH--IIIQWTKPESDGGNEISNYLVDK 29278
Query: 630 SENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE 688
E + WT + T + V L+ YQFR+ AVN G + S+ + +S E
Sbjct: 29279 REKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP 29338
Query: 689 PPT-APPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
T PP T SI + W P I+ GY++ Y+ T+A
Sbjct: 29339 SYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIV-GYVLEMQEKDTDQWYRVH--TNA 29395
Query: 748 DVNN--LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNS 805
+ N + DL + Y VAA N G+ YS + E +P + + +
Sbjct: 29396 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 29455
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
TIR A ++ + +I W + + + S+ + + K
Sbjct: 29456 VTIRA--GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-----VDKVN 29508
Query: 866 EYFTSVLCFTTPGD-GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y G +S LV+ + D PGP + E+ S+ ++W+ P G
Sbjct: 29509 RYDAGKYTIEAENQSGKKSATVLVKVY-DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 29567
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + E + + TL YR++GL T Y V G G+ T
Sbjct: 29568 PVNNYIVEKREAAMRAFKTVTTKCSKTL-YRISGLVEGTMYYFRVLPENIYGIGE-PCET 29625
Query: 984 ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEA-QVGVVGEGEEW 1041
+ + E+P P L + ++ +VTL + +P YDG + ++ +++EA + G E W
Sbjct: 29626 SDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT----ERW 29681
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQTLQAPPDMA 1099
+ + L +P V LN Y FR+R N G S P + + +Q L+ P +
Sbjct: 29682 MKVVTL--KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTID 29739
Query: 1100 PANVSLRTAS-------ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS---DGHGKTLS 1149
+ + +T E + + P P + G K++ S + H K
Sbjct: 29740 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWF----FAGSKLRESERVTVETHTKVAK 29795
Query: 1150 HVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
+ R+ TI D E+T ++ N G+ + V+ + P +GP + +
Sbjct: 29796 LTI-----RETTIRDTGEYT-----LELKNVTGTTSETIKVIILDKPG-PPTGPIKIDEI 29844
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGK 1268
TS + + W E PE D + GY V E+ +P + V + +RS + T L +
Sbjct: 29845 DATS--ITISW-EPPELDGGAPLSGYVV---EQRDAHRPGWLPVSESVTRSTFKFTRLTE 29898
Query: 1269 YVLYEVQVLAFTRIGDGSPSHPPILE-RTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAP 1327
Y +V A R G GS ++E R+ +PGPP + +V + L W PP
Sbjct: 29899 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 29958
Query: 1328 NGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA 1387
G + I R V + + +Y +TGL Y R+TA +G G+ +
Sbjct: 29959 GGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPS 30018
Query: 1388 EAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPS 1444
+V + P P P V D SV L+W P +G S V Y I+ +++
Sbjct: 30019 RPSKPIVAMDPIAPPGKPQNPRV--TDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ 30076
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEA 1504
W + + + + + L Y+FRV A N G E P E
Sbjct: 30077 HEWTKCNTTPT-KIREYTLTHLPQGAEYRFRVLACNAGGPGE--------------PAEV 30121
Query: 1505 PTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-----FTLRGINN 1559
P + VT ++ + D+ RY+E ++ G ++G
Sbjct: 30122 PGTVKVTE------MLEYPDYELDE----------RYQEGIFVRQGGVIRLTIPIKGKPF 30165
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
P W + S R + S T EL R Y+ V E + V++
Sbjct: 30166 PICKWTKEGQDISKRAMIATSETHTELVIKEADRG---DSGTYDLVLENKCG-KKAVYIK 30221
Query: 1620 EAV---PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG---NLTE 1673
V P + + + V+W PP D DI GY + E + +
Sbjct: 30222 VRVIGSPNSPEGPLEYDDIQVRSVRVSWR-PPADDGGADILGYILERREVPKAAWYTIDS 30280
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQAAPSAPSS- 1729
RV+ S+ +K L Y V+A N G P +T P PS+
Sbjct: 30281 RVR-----GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP 30335
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ ++T +SV++SW P+ G + GY + + S K V + + V
Sbjct: 30336 PEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETS----TDKWVRHNKTQITTTMYTV 30391
Query: 1789 KDLAEGVTYRFRIRAKT----FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHW 1844
L Y+FRI A+ P E V P + P + I+ ++ + W
Sbjct: 30392 TGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQW 30451
Query: 1845 SSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAV 1903
+ G I Y +E R S + W K + + F++ L Y+FRV A
Sbjct: 30452 EKPECDGGKEILGYWVEYRQSGDSAWK---KSNKERIKDKQFTIGGLLEATEYEFRVFAE 30508
Query: 1904 NDYGFGTPSSPSQSV 1918
N+ G P + S+
Sbjct: 30509 NETGLSRPRRTAMSI 30523
Score = 211 bits (537), Expect = 6e-54
Identities = 408/1878 (21%), Positives = 683/1878 (36%), Gaps = 218/1878 (11%)
Query: 136 RIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGD 192
R+ P+P +TW ++G+ + R+ + + L I V D G+Y + A KN
Sbjct: 17931 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISA---KNSS 17987
Query: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKL 247
+ V + GP + T + T + G SE+T V +P K
Sbjct: 17988 GHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQK- 18046
Query: 248 HIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP 307
W S SD +RL N ++ Y+ A + P++ + + P
Sbjct: 18047 --GW-------SIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINP 18097
Query: 308 PQFVKEPER-HITAEMEKVVDIPCQAKGVP--PPSITWYKDAAVVEVEKLTRFRQRN--D 362
EPE HI + + V + + P+++++ + + + R + + +
Sbjct: 18098 IDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKE 18157
Query: 363 GGLQISGLVPDDTGMFQCFARNAAGE---VQTSTYLAVTSIAPNITRGPLDS--TVIDGM 417
+ V + F+ +N GE V+T + + + L TV G
Sbjct: 18158 THYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 18217
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRF---TPLESGSLLISPTHISDAGTYT 474
++ L G P P + W K + A+ + PR T +S ++ SD G Y
Sbjct: 18218 TIRLEAGVRGKPFPEVAWTKDKD--ATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 18275
Query: 475 CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPR---------- 524
ATN+ G A A + V + KP +++ +S C V DP
Sbjct: 18276 VTATNTAGSFVAYATVNV-----LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQN 18330
Query: 525 ------VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGND 578
T R +W AT+ T RL IGT +
Sbjct: 18331 YILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGT-------GPPTE 18383
Query: 579 SRSAHLRVR-QLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP- 635
S+ + + P P+ P T V + + + W P +DG + Y LE E ++
Sbjct: 18384 SKPVIAKTKYDKPGRPDPPEVT--KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 18441
Query: 636 WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--PEEPPTAP 693
W + S P+ + V+ L+P YQFR+ A N++G G+ S + V P EPP P
Sbjct: 18442 WVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP-GP 18499
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII---------------RYCLAGLPVG 738
P N T SI + W P I+ GY++ + C A +
Sbjct: 18500 PTNFRVVDTTKHSITLGWGKPVYDGGAPII-GYVVEMRPKIADASPDEGWKRCNAAAQLV 18558
Query: 739 YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV 798
+ +T D N YE V A N G+G +++ E ++ + P +
Sbjct: 18559 RKEFTVTSLDENQ----------EYEFRVCAQNQVGIG-RPAELKE-AIKPKEILEPPEI 18606
Query: 799 HAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFV 858
+A+ + P F + + W + V R D +
Sbjct: 18607 DLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNV----VRKGQVDLVDTMAF 18662
Query: 859 SGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP 918
+ T + T + D PGPV L S++ TS VSW P
Sbjct: 18663 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPP 18722
Query: 919 GEKNGI-LTGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
G +T Y + E +R T + VT + + + VT L Y V A+ G
Sbjct: 18723 ENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS--FHVTNLVPGNEYYFRVTAVNEYGP 18780
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLV--EAQ 1031
G + + + P P PP L ++ + S TL + P DG I ++ +
Sbjct: 18781 GVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREE 18840
Query: 1032 VGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS---RK 1088
E+ ++ L S+ V L Y FR+ N VG S P +
Sbjct: 18841 EQPADRWTEYSVVKDL-------SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 18893
Query: 1089 IQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
+ L P + P ++++ + + E G P K+ + + T
Sbjct: 18894 KEQLLPPKILMPEQITIKAGKKLRI--------EAHVYGKPHPT---CKWKKGEDEVVTS 18942
Query: 1149 SHVVQDRVERD--YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNV 1206
SH+ + + I+D+ + A N+ G+ VV P P ++
Sbjct: 18943 SHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG-PPQPPFDI 19001
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL-----VEGNSSRSA 1261
S + + S+ W +P D + Y V + D W+ V S R
Sbjct: 19002 SDIDADACSL--SW-HIPLEDGGSNITNYIV----EKCDVSRGDWVTALASVTKTSCRVG 19054
Query: 1262 QLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLI 1320
+L +Y+ +V A R G P + P ++ + VP P +V + +
Sbjct: 19055 KLIPGQEYIF---RVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVA 19111
Query: 1321 WQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
W P + G I+ Y I + + + L S +Y GL Y FRI A
Sbjct: 19112 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRST-EYPCAGLVEGLEYSFRIYALN 19170
Query: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQ 1438
+ G ++ T R PP +P V DV +V L W P DG S + Y ++
Sbjct: 19171 KAGSSPPSKPTEYVT-ARMPVDPPGKPEV--IDVTKSTVSLIWARPKHDGGSKIIGYFVE 19227
Query: 1439 TRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTL 1497
+LP +W ++A + L+ Y+FR A + S SE S+ +T L
Sbjct: 19228 ACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL 19287
Query: 1498 QAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
+V P SV ++ + N L T+ G
Sbjct: 19288 AE---------NVPPRIDLSVAMKSLLTVKAGTNVCL----------------DATVFGK 19322
Query: 1558 NNPGATWAE----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPP 1613
P +W + L ++ + +L EL ++N+ + ++ N+ G ++
Sbjct: 19323 PMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 19382
Query: 1614 QEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE 1673
+V P +V ++ + + ++WE PPL+ +I Y + E R N +
Sbjct: 19383 LKVL----DKPGPPASVKINKMYSDRAMLSWE-PPLEDGGSEITNYIVDKRETSRPNWAQ 19437
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFN--AAGDGPRSTPTQGQTQQAAPSAPSSVK 1731
T+ + SV+ K + G+ Y + A N GD + P + P
Sbjct: 19438 VSATVPITSCSVE-KLIEGH-EYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 19495
Query: 1732 FSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD 1790
S +T + VSW+ P G + GY L V+ V+ K LK
Sbjct: 19496 ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VNRKPIIERTLKATG 19551
Query: 1791 LAEGVTYRFRIRAKTFTYGPEIEANVTTG----PGEGAPGPPGVPIIVRYS-SAIAIHWS 1845
L EG Y FR+ A GP ++ + + PGPP P + + S++++ W
Sbjct: 19552 LQEGTEYEFRVTAIN-KAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW- 19609
Query: 1846 SGDP---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
G P G PI Y++E + +D W + ++P+ + F + L Y FRV A
Sbjct: 19610 -GKPAYDGGSPIIGYLVEVKRADSDNW--VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYA 19666
Query: 1903 VNDYGFGTPSS-PSQSVP 1919
VN G+ PS P + P
Sbjct: 19667 VNKIGYSDPSDVPDKHYP 19684
Score = 211 bits (537), Expect = 6e-54
Identities = 342/1451 (23%), Positives = 555/1451 (38%), Gaps = 168/1451 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W K G + +I S L I D G YT + G + V +
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 20472
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAP-WTVLLASVDPKA 647
P P PV +S V LTWT P DG SP+ YILE E + WTV+ S D ++
Sbjct: 20473 P-GPPGPVE-ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVV--SEDIQS 20528
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
L+ Y FR+ AVN GKG+ + + P PP+ S T +
Sbjct: 20529 CRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTA 20588
Query: 708 MIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKN-ITDADVNNLLLEDLIIWTNYEIE 766
+ W+ P + + I ++ R L K ++D L++ + YE
Sbjct: 20589 TVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQE---GSTYEFR 20645
Query: 767 VAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824
V+A N AG+G S ++ P PP N H T + W P +
Sbjct: 20646 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH------YD 20699
Query: 825 QGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG--FVSGLKKFTEYFTSVLCFTTPGDGPR 882
G ++ + E ++ + ++ + V L+ +Y + G G
Sbjct: 20700 GGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEP 20759
Query: 883 STPQLVRTHEDVPGPVGHLSFSEILDT-------SLKVSWQEPGEKNGILTGYRISWEEY 935
+ V E P L +E+ T S+++ G +T + +
Sbjct: 20760 AVIPDVEIVEREMAPDFELD-AELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK 20818
Query: 936 NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGP 995
NR N T + + T TIE A K G V+ + + PGP
Sbjct: 20819 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPA--GKKSGFVNVRVLDT------PGP 20870
Query: 996 PTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDAR 1054
NL ++I SVTL + P DG + I+ ++VE + + +
Sbjct: 20871 VLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS------YSTATTKCHKC 20924
Query: 1055 SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLW 1114
+ +V L+ Y FR+ N G P++ + ++ +AP P ++++ +++++
Sbjct: 20925 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSP--PDSLNIMDITKSTVS 20982
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
L W P+ +++G + GY I+ R T V+ + + +L E EY Q
Sbjct: 20983 LAW---PKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL---ECVVRNLTEGEEYTFQ 21036
Query: 1175 VQAFNAIG-SGPW-SQTVVGRTRESVPS---SGPTNVSALATTSSSMLVRWSEVPEADRN 1229
V A N+ G S P S+ V+ + + +P G +A ++ V E+P R
Sbjct: 21037 VMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV---EIPVLGRP 21093
Query: 1230 GLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFT------RIG 1283
+ +K K + V ++ ++ + + + V + T +G
Sbjct: 21094 KPTVTWK-----KGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVG 21148
Query: 1284 DGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342
D ++ + D+PGPP G I F EV + V W PP G+ ++ + T
Sbjct: 21149 D-------VITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 21201
Query: 1343 TTANTATVEVLAPSARQ-YTATGLKPESVYLFRITAQTRKGWGEA-AEALVVTTEKRDRP 1400
+ T VE+ R Y AT L Y FR+ AQ R G G A +V P
Sbjct: 21202 DS--TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVP 21259
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVSHNA 1458
PP P V V S+ +SW EP SDG SP+ Y ++ +E W + A V N
Sbjct: 21260 GPPGTPQVTA--VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 21317
Query: 1459 --SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTT 1515
SS + D + +Y+FRV A N G S+ S+ SE + L P P L++T HT
Sbjct: 21318 FKSSGLTDGI----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTV 21373
Query: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
T ++W P + G GF+I + + + P W + N
Sbjct: 21374 T---LKWAKP---EYTG---GFKIT----------SYIVEKRDLPNGRWLKA-------N 21407
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGPSSPPQEVFVGEAVPTAAPR----- 1628
S ++ + L + YE R+ NA G PS P + + V AP+
Sbjct: 21408 FSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDV 21465
Query: 1629 ----NVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
V++ A +L DV+ PPP + D + G +K +
Sbjct: 21466 KFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD--------GKELEGTAKLEIKIADFST 21517
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
N V K+ T + ++ A N G + + P P +V +E+T+ +
Sbjct: 21518 NLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAV--TEVTSEKCVL 21574
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLW-LKVKDLAEGVTYRFRI 1801
SW P G + +V + S++ +V + LKV L +G Y FR+
Sbjct: 21575 SWFPPLDDGGAKIDHYIVQKR-----ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRV 21629
Query: 1802 RA-KTFTYGPEIEANVTTGPGE-GAPGPPGVPIIVRYSS-AIAIHWSSGDP-GKGPITRY 1857
A + G +E+ G P PP P + + ++ + W D G I Y
Sbjct: 21630 MAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 21689
Query: 1858 VIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
++E R W IK K ++ + + L G Y+FR++A N G PS S
Sbjct: 21690 IVERRDKAGQRW---IKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-- 21744
Query: 1918 VPAQKANPFYE 1928
PFY+
Sbjct: 21745 -------PFYK 21748
Score = 211 bits (537), Expect = 6e-54
Identities = 438/1934 (22%), Positives = 700/1934 (36%), Gaps = 355/1934 (18%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY----YVQAVNDKNGDNKTS 196
P P+VTW +D + + I T TL+I+ P+ RY +V + + G K S
Sbjct: 20804 PAPEVTWTKDNINLKNRANIENTESFTLLII----PECNRYDTGKFVMTIENPAG--KKS 20857
Query: 197 QPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKLHIIW 251
+ + V + GP + PT I T ++ G S +T +I+
Sbjct: 20858 GFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT------------NYIVE 20905
Query: 252 KKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFV 311
K++ S + TG G CE R + G EP V
Sbjct: 20906 KREATRKSYSTATTKCHKCTYKVTGLSEG---CEYFFRVMAENEYGIGEPTETTEP---V 20959
Query: 312 KEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLV 371
K E + ++DI S+ W K ++DGG +I+G V
Sbjct: 20960 KASEAPSPPDSLNIMDITKST-----VSLAWPK--------------PKHDGGSKITGYV 21000
Query: 372 PD-------------DTGMFQCFARN-AAGEVQTSTYLAVTS------------------ 399
+ +C RN GE T +AV S
Sbjct: 21001 IEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 21060
Query: 400 IAPNI-TRGPLDSTVI--DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLE 456
+ P + RG VI G ++ + G P+P +TW+KG++IL Q F
Sbjct: 21061 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK--QTQRVNFETTA 21118
Query: 457 SGSLL-ISPTHISDAGTYTCLATNSRG----------------------VDEASADLVVW 493
+ ++L I+ SD+G Y A N G DE S+D V +
Sbjct: 21119 TSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 21178
Query: 494 ARTRITKPPQDQS-------VIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
+ PP++ V++ Q V V IR ++ T G E R+
Sbjct: 21179 S----WDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-IRTTYKATRLTTGLEYQFRV 21233
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
+ + T + + Y +V P P P T V +
Sbjct: 21234 KAQNRYGVGPGITSACIVANYPFKV------------------PGPPGTPQVT--AVTKD 21273
Query: 607 AINLTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFR 664
++ ++W +P DG SP++ Y +E E N W + ++ P GL +Y+FR
Sbjct: 21274 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP-GNIFKSSGLTDGIAYEFR 21332
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-L 723
+ A N GK + SK +E + + P PP + T ++ ++W P + G +
Sbjct: 21333 VIAENMAGKSKPSKPSEPMLALD--PIDPPGKPVPLNITRHTVTLKWAKP--EYTGGFKI 21388
Query: 724 KGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782
YI+ LP G K N ++ N + L YE V A N+AG
Sbjct: 21389 TSYIVE--KRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG-------- 21438
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
PP +E +++ T R AP + L A E + E
Sbjct: 21439 --------AISPP----SEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 21486
Query: 843 VTARPNFQDSIHVGFVSGLK----KFTEYFTSVL----------CFTTPGDGPRSTPQLV 888
P + S + G K ++ T+++ +T P + +
Sbjct: 21487 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHI 21546
Query: 889 RTHE--DVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTH 944
+ D PG P G L+ +E+ +SW P + G + Y + E +R
Sbjct: 21547 FNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA 21606
Query: 945 YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISN 1003
VT + +VT L Y V A+ G G+ + + + + P P PP N ++
Sbjct: 21607 SEVQVT-KLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTT 21665
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I S+ + + P DG + I ++VE + G+ W+ ++ D R +V L
Sbjct: 21666 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKA---GQRWIKCNK-KTLTDLR-YKVSGLT 21720
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPS---RKIQTLQAPPDMAPANVSLRTASETSLWLRW-M 1118
Y FR+ N G S PS S + T+ P P N + S +S+ + W
Sbjct: 21721 EGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG--PPGNPRVLDTSRSSISIAWNK 21778
Query: 1119 PLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAF 1178
P+ Y+G E GY ++ + + + YTI L E EY++++ A
Sbjct: 21779 PI----YDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAM 21834
Query: 1179 NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR---------------WSEV 1223
N+ G G +V T ++ P + A + +R EV
Sbjct: 21835 NSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEV 21892
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
A +G + + K T L+ GN +R GKY+L +
Sbjct: 21893 KWARDHG-----ESLDKASIESTSSYTLLIVGNVNRFDS----GKYIL---------TVE 21934
Query: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTT 1343
+ S S + + D PGPP + EV TSV L W PP G + I + +T
Sbjct: 21935 NSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 21994
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPP 1403
+TV + L+ Y FR+ A+ G G AE + + +RP PP
Sbjct: 21995 RKAYSTVATNCHKT-SWKVDQLQEGCSYYFRVLAENEYGIGLPAET-AESVKASERPLPP 22052
Query: 1404 SRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462
+ + DV SV LSWE P DG S + Y ++ + S +WA + +
Sbjct: 22053 GK--ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA---TCATVKVTEAT 22107
Query: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRW 1522
+ L Y FRV A N+ G S+ P LSV P ++I
Sbjct: 22108 ITGLIQGEEYSFRVSAQNEKGISD------------------PRQLSV-PVIAKDLVI-- 22146
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATW------AELTSM 1570
PPA F++ + + L G L+ G P TW + T+
Sbjct: 22147 -PPA----------FKLLFN--TFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTR 22193
Query: 1571 YSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV 1630
+ + SL + Y ++++ N+ GE + V PT V
Sbjct: 22194 VNAESTENNSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIVLDKPGPPTGP---V 22248
Query: 1631 VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNL 1690
+ TA + ++W PP D I Y + + T ++ + +A ++K L
Sbjct: 22249 KMDEVTADSITLSWGPPKYDG-GSSINNYIVE--KRDTSTTTWQIVSATVARTTIKACRL 22305
Query: 1691 TGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
Y +AA N G S PT Q P P + + + S+ V W
Sbjct: 22306 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWN--- 22362
Query: 1749 FPNGILEGYRLVYEPCSPVDGVSKIVTVDV---KGNSPLWLKVK------------DLAE 1793
EP S DG S+++ + + NS LW+K+ L E
Sbjct: 22363 -------------EPIS--DGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 22407
Query: 1794 GVTYRFRIRAKTFT----YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD- 1848
GV Y FR+ A+ E V P + PG P I+ R +++ + W
Sbjct: 22408 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCD-PPGRPEAIIVTR--NSVTLQWKKPTY 22464
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG- 1907
G IT Y++E + EG W +K + F + L Y+FRVIA N G
Sbjct: 22465 DGGSKITGYIVEKKELPEGRW---MKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 22521
Query: 1908 FGTPSSPSQSVPAQ 1921
F PS + ++ A+
Sbjct: 22522 FSEPSESTGAITAR 22535
Score = 210 bits (535), Expect = 1e-53
Identities = 345/1488 (23%), Positives = 556/1488 (37%), Gaps = 155/1488 (10%)
Query: 506 SVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LDRNGSLHISQTWSGDI 564
+V GT+ + VT P I W K L + I + + ++ I + D
Sbjct: 13701 TVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 13758
Query: 565 GTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLI 623
GTY ++ G + + V P P ++ V + LTW P D G S +
Sbjct: 13759 GTYIIEAVNVCGRATAVVEVNVLDKPGPPA--AFDITDVTNESCLLTWNPPRDDGGSKIT 13816
Query: 624 RYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
Y++E ++ W L ++V K T+ L+P + Y FR+ A N G G+ + +
Sbjct: 13817 NYVVERRATDSEVWHKLSSTV--KDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 13874
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
+ + P PP + S T ++ + W P + + I GY + +
Sbjct: 13875 TAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT-GYWVERLDPDTDKWVRCN 13933
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHA 800
+ D ++ L Y V A N AG G S ++ P PPG
Sbjct: 13934 KMPVKDTT-YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTV 13992
Query: 801 EATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ T++R W P I + Y + + +E V + P Q + G
Sbjct: 13993 KDVGKTSVRLNWTKPEHDGGAKI-ESYVIEMLKTGTDEWVRVAEGVPTTQH-----LLPG 14046
Query: 861 LKKFTEYFTSVLCFTTPGDGPRSTPQ---LVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G+ S P L R P P L I + + W
Sbjct: 14047 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 14106
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +T Y + + R + T + VT LT + Y VAA + GQ
Sbjct: 14107 PEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDT-KCTVTPLTEGSLYVFRVAAENAIGQ 14165
Query: 977 GQVSA--STISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVG 1033
+ ++ + PGPP L + ++ R V L++ P DG I R+++E +
Sbjct: 14166 SDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKER 14225
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
+ G W+ + + PD + V D+ T F++R N G PS+P+ +I +++
Sbjct: 14226 L---GTRWVKAGKTAG-PDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT-EILSIE 14279
Query: 1094 AP--PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKI--------KYSRSDG 1143
P P P ++ + A + + W P E NG +GY + K+ R +
Sbjct: 14280 DPTSPPSPPLDLHVTDAGRKHIAIAWKP---PEKNGGSPIIGYHVEMCPVGTEKWMRVNS 14336
Query: 1144 HG-KTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG---SGPWSQTVVGRTRESVP 1199
K L V++ V D EY ++V+A NAIG S+ VV + + P
Sbjct: 14337 RPIKDLKFKVEEGVVPD---------KEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKP 14387
Query: 1200 SSG--PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
+ ++ + S+ V + VP V +K + K SD L N
Sbjct: 14388 TIDLETHDIIVIEGEKLSIPVPFRAVPVPT----VSWHKDGKEVKASDR-----LTMKND 14438
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFT---RIGDGSPSHPPILERTLDDVPGPPMGILFPEVRT 1314
SA L + K V + + T ++G + S + + +PGP I ++
Sbjct: 14439 HISAHLE-VPKSVRADAGIYTITLENKLGSATAS----INVKVIGLPGPCKDIKASDITK 14493
Query: 1315 TSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFR 1374
+S +L W+PP G + + + R V + + +T L P Y FR
Sbjct: 14494 SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFR 14552
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSWEPGS-DGLSPV 1432
+ A + G GE E L +D QPP P+ V+ + A ++ ++W+P DG S +
Sbjct: 14553 VKAVNKVGGGEYIE-LKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 14611
Query: 1433 RYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE 1492
Y I+ RW + + ++ L+ Y+FRV+A N G SE S +
Sbjct: 14612 MGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATP 14670
Query: 1493 SLTTLQAAPDEAPTIL-------------------SVTPHTTTSVLIRWQP------PAE 1527
T P +AP ++ S +P+ T I W P E
Sbjct: 14671 P--TKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPT----ITWIKDENVIVPEE 14724
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
K L +R R+ + F L LT S+ N + D
Sbjct: 14725 IKKRAAPL---VRRRKGEVQEEEPFVL-----------PLTQRLSIDNSKKGESQLRVRD 14770
Query: 1588 NLNK-HRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEP 1646
+L H Y I++ + + + P + V P N V T + WEP
Sbjct: 14771 SLRPDHGLYMIKVENDHGIAKAPCT------VSVLDTPGPPINFVFEDIRKTSVLCKWEP 14824
Query: 1647 PPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAA 1706
P LD +I Y + + + + V T L + L Y+ V A N
Sbjct: 14825 P-LDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 14883
Query: 1707 GDGPR--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
G GP S P + P AP ++T+ S+ V W P+ + GY L
Sbjct: 14884 GPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREV 14943
Query: 1765 SPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTT 1818
+ V+K + +K N V L EG+TY FR+ A+ + P +
Sbjct: 14944 NSTHWSRVNKSLLNALKAN------VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAH 14997
Query: 1819 GPGEGAPGPPGVPIIVRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIP 1877
P PGPP + S+ I + W G G I Y ++ + W + +
Sbjct: 14998 DP-ISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI 15056
Query: 1878 KEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
K V YT ++ G Y RV AVN G G P A+ P
Sbjct: 15057 K-VRQYTVKE--IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP 15101
Score = 207 bits (527), Expect = 9e-53
Identities = 337/1448 (23%), Positives = 550/1448 (37%), Gaps = 155/1448 (10%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGGNDSRS 581
P+ T+ W KDG TL + + + SL I + D+GTY V ++ G+ +
Sbjct: 25422 PQATVN--WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 25479
Query: 582 AHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVL 639
+ V P P P+ + V +I ++W P +DG + YI+E E + W ++
Sbjct: 25480 ITIIVLDRP-GPPGPIR-IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 25537
Query: 640 LASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIA 699
+V TS+ + L YQFR+CA N GK +S+ + V+ P PP
Sbjct: 25538 SQAV--ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV 25595
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
T ++++ WQ P + ++ GY + Y + + I AD + + L
Sbjct: 25596 VHATKSTMLVTWQVPVNDGGSRVI-GYHLEYKERSSILWSKANKILIADTQ-MKVSGLDE 25653
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
YE V A N AG+G SK E P PPG ++ W+ P
Sbjct: 25654 GLMYEYRVYAENIAGIGK-CSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPH--- 25709
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEY----FTSVLCF 874
+ G K+ + E+ E + N+ + F V+ L + Y F
Sbjct: 25710 ---YDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAAD 25766
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS----LKVSWQEPGEKNGILTGYRI 930
+ + P +V+ + P + + F +++ LK++ G +++ +
Sbjct: 25767 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 25826
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPP 990
E R T + + L + Y + + + V+ +
Sbjct: 25827 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK---- 25882
Query: 991 ELPGPPTN-LGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP L I+ + +L + RP DG I ++VE + W +
Sbjct: 25883 --PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET---SHLAWTICE--- 25934
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP--SQPSRKIQTLQAPPDMAPANVSLR 1106
E S +V L Y FR+ VN G P S + + P P ++ +
Sbjct: 25935 GELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEIT 25992
Query: 1107 TASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV-VQDRVERDYTIED- 1164
+ ++ S+ L W E +G E GY I+ + +L V V + D ++
Sbjct: 25993 SVTKESMTLCWS---RPESDGGSEISGYIIERREKN----SLRWVRVNKKPVYDLRVKST 26045
Query: 1165 -LEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESV----PSSGPTNVSALATTSSSMLV 1218
L E EY +V A NA G S P + + R + V P S P V + TT + +
Sbjct: 26046 GLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTT---ITI 26102
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLT--GLGKYVLYEVQV 1276
W + P D + GY V YK+ D DT W S R + T GL Y +V
Sbjct: 26103 AWVK-PLFDGGAPITGYTVEYKKSD-DTD---WKTSIQSLRGTEYTISGLTTGAEYVFRV 26157
Query: 1277 LAFTRIGDGSPSH---PPILERTLDDVPGPPMGILFPEVRTTSV---RLIWQPPAAPNGI 1330
+ ++G PS P I + ++ P+ + E+R T + + G
Sbjct: 26158 KSVNKVGASDPSDSSDPQIAKEREEE----PLFDIDSEMRKTLIVKAGASFTMTVPFRGR 26213
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ + + +T A V+ S T + +T Q +A +L
Sbjct: 26214 PVPNVLWSKPDTDLRTRAYVDT-TDSRTSLTIENANRNDSGKYTLTIQNVL----SAASL 26268
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWAL 1449
+ + D P PP+ VQ DV S +LSW+ P +DG +PV+ Y I+ RE W
Sbjct: 26269 TLVVKVLDTPGPPTNITVQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWV- 26325
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
S + + N S+ V L+ Y FRV N+ G +E E + + P L
Sbjct: 26326 -SVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKP--SPPEKLG 26382
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + SV + W P D G RI + + + + W +
Sbjct: 26383 VTSISKDSVSLTWLKPEHDG------GSRIVH----------YVVEALEKGQKNWVKCAV 26426
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------P 1623
S T + + L ++ Y R+ N G S P+E+ + + P
Sbjct: 26427 AKS---------THHVVSGLRENSEYFFRVFAENQAG---LSDPRELLLPVLIKEQLEPP 26474
Query: 1624 TAAPRN-----VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
+N V V + ++D+ PL G + T R T
Sbjct: 26475 EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL--------KATMRFNTE 26526
Query: 1679 FLAEN-SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737
AEN ++ LK A + A N++G + P+ P V S++T
Sbjct: 26527 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP--VVISDITE 26584
Query: 1738 TSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVT 1796
SV + WE P++ G + Y L+ S TV + +KV L G
Sbjct: 26585 ESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV-----ARTMMKVMKLTTGEE 26639
Query: 1797 YRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKG 1852
Y+FRI+A+ F I+ A VT PGPP P + + +I + W G
Sbjct: 26640 YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGS 26699
Query: 1853 PITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ Y +E + + LW K + + + F + + G+ Y+FRV A N G G PS
Sbjct: 26700 AVVGYHLEMKDRNSILWQKANKLV---IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPS 26756
Query: 1913 SPSQSVPA 1920
PS+ V A
Sbjct: 26757 HPSEPVLA 26764
Score = 207 bits (526), Expect = 1e-52
Identities = 333/1443 (23%), Positives = 538/1443 (37%), Gaps = 164/1443 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W DG+ + T+ H + D S L I D G Y V +A G+ + + HL V +
Sbjct: 17544 WTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDV 17603
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P+ L + ++W P D G SP+I YI+E + +++S K T
Sbjct: 17604 PGPPTGPINILDVTPEH-MTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 17661
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ + L Y FR+ A N +G G T V+ + P +PP + + T +
Sbjct: 17662 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT 17721
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVA 768
+ W P + I Y+ R + G V I D + L YE V
Sbjct: 17722 VSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADL---KFRVTGLYEGNTYEFRVF 17778
Query: 769 AYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG 826
A N AGL SS + P PP N + + T W P + G
Sbjct: 17779 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS------DGG 17832
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIH--VGFVSGLKKFTEYFTSVLCFTTPGDG-PRS 883
++ + E ++ T R N + I V GL + EY + G+G PR
Sbjct: 17833 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 17892
Query: 884 TPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYR------ISWEEYNR 937
+ V + + H E+ T V G+ IL + I+W + +
Sbjct: 17893 LAESV-----IAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 17947
Query: 938 TNTR-----VTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
R + LP V L+ + Y I + QG + + +
Sbjct: 17948 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVL------DR 18001
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
PGP NL ++N+ + T+ + P +G + I+ ++VE + + W ++ +++
Sbjct: 18002 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR---KPNQKGWSIV---ASDV 18055
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQ---PSRKIQTLQAPPDMAPANVSLRTA 1108
R ++ +L Y FR+ N VG P + P I + P + P N+ +
Sbjct: 18056 TKRLIKA-NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGE--PENLHIADK 18112
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLE 1166
+T ++L+W +Y+G ++ Y + + SD + ++ E Y ++
Sbjct: 18113 GKTFVYLKWR---RPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK---ETHYMVDRCV 18166
Query: 1167 EWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS-------SGPTNVSALATTSSSMLVR 1219
E Y +VQ N G W +T +E + SG V A T VR
Sbjct: 18167 ENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVR 18226
Query: 1220 WSEVPEA----DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQ 1275
PE D++ L K +F L + S GKYV
Sbjct: 18227 GKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDG------GKYV----- 18275
Query: 1276 VLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ 1335
V A G S + D PGP + +V + + W PP G +
Sbjct: 18276 VTATNTAG----SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 18331
Query: 1336 ITHRLNTTTA--NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VV 1392
I + T +T + VL P T T L + Y+FR+ A+ + G G E+ V+
Sbjct: 18332 ILEKCETKRMVWSTYSATVLTPGT---TVTRLIEGNEYIFRVRAENKIGTGPPTESKPVI 18388
Query: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWA-LH 1450
K D+P P P V + V + + W P DG + Y ++ +E S RW ++
Sbjct: 18389 AKTKYDKPGRPDPPEVTK--VSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN 18446
Query: 1451 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ-AAPDEAPTILS 1509
+++ V L P Y+FRVKA N+IG E S S + P PT
Sbjct: 18447 KSAIPERRMK--VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFR 18504
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
V T S+ + W P D ++G+ + R + + +P W +
Sbjct: 18505 VVDTTKHSITLGWGKPVYDG-GAPIIGYVVEMRPKIADA----------SPDEGWKRCNA 18553
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG------PSSPPQEVFVGEAVP 1623
+ ++ + +L++++ YE R+ N VG G + P+E+ +
Sbjct: 18554 AAQLVR------KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEID 18607
Query: 1624 TAAP--RNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL- 1678
A + V+V +L V P P + K+ R + V T+
Sbjct: 18608 LDASMRKLVIVRAGCPIRLFAIVRGRPAP------KVTWRKVGIDNVVRKGQVDLVDTMA 18661
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
FL + + Y+ +V+ A A R T P S +K S++T T
Sbjct: 18662 FLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDT--------PGPVSDLKVSDVTKT 18713
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYR 1798
S +VSW P+ G + +V E VT +VK S V +L G Y
Sbjct: 18714 SCHVSWAPPENDGGSQVTHYIV-EKREADRKTWSTVTPEVKKTS---FHVTNLVPGNEYY 18769
Query: 1799 FRIRAKTFTYGPEIEANV-----TTGPGEGAPGPPGVPIIVRYSSAIAIHW-----SSGD 1848
FR+ A YGP + +V + P P + + ++ + W G
Sbjct: 18770 FRVTAVN-EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGA 18828
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGF 1908
G IT Y E +P+D ++KD+ V+ LK G Y FRV A N G
Sbjct: 18829 KIDGYITSYREEEQPADRWTEYSVVKDLSLVVTG-------LKEGKKYKFRVAARNAVGV 18881
Query: 1909 GTP 1911
P
Sbjct: 18882 SLP 18884
Score = 204 bits (520), Expect = 6e-52
Identities = 375/1638 (22%), Positives = 639/1638 (39%), Gaps = 191/1638 (11%)
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAG---EVQTSTYLAVTS----IAPNITRGP--LDST 412
D +++GLV D F+ ARNAAG E ST A+T+ P I+ P D+
Sbjct: 22495 DTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTG-AITARDEVDPPRISMDPKYKDTI 22553
Query: 413 VID-GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
V+ G S + + G P P I W KG++ L S + +L + + SL + D+G
Sbjct: 22554 VVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAVRVDSG 22612
Query: 472 TYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQA---------------SMV 516
Y A N G + ++ V R PP+ VI G A S +
Sbjct: 22613 NYILKAKNVAGERSVTVNVKVLDR---PGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDI 22669
Query: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG- 575
+ R T R +W A + T S +++ G+ YT R+++
Sbjct: 22670 INYIVERRETSRLVWTVVDANVQTL-----------SCKVTKLLEGN--EYTFRIMAVNK 22716
Query: 576 ---GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILE 628
G S + + +P AP+ P T TV + ++ + W +P DG S ++ Y+LE
Sbjct: 22717 YGVGEPLESEPVVAKNPFVVPDAPKAPEVT--TVTKDSMIVVWERPASDGGSEILGYVLE 22774
Query: 629 MSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT--ERVSL 685
+ WT + + + V GL+ Y+FR+ A N G + S + ++
Sbjct: 22775 KRDKEGIRWTRCHKRLIGE-LRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 22833
Query: 686 PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
P P PP N T S+ + W P + G ++GYI+ C +
Sbjct: 22834 PIYKP-GPPNNPKVIDITRSSVFLSWSKP--IYDGGCEIQGYIVEKCDVSVGEWTMCTPP 22890
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T + N+ +E L+ Y + A N AG+G ++ ++ P ++ E
Sbjct: 22891 TGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRK 22950
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLK 862
IR F+ + + W E + ++ +F + L
Sbjct: 22951 IINIRA--GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV-------LD 23001
Query: 863 KFTEYFTSVLCFTTP-GDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEK 921
Y + T G +S VR D P P +L +EI S+ ++W+ P
Sbjct: 23002 NVNRYDSGKYTLTLENSSGTKSAFVTVRV-LDTPSPPVNLKVTEITKDSVSITWEPPLLD 23060
Query: 922 NGI-LTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ 978
G + Y + E R + VT+ N +++ L +Y V A G G
Sbjct: 23061 GGSKIKNYIVEKREATRKSYAAVVTNCHKN---SWKIDQLQEGCSYYFRVTAENEYGIG- 23116
Query: 979 VSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+ A T E+P PP + + ++ SV+L + +P +DG + I +++VE Q
Sbjct: 23117 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ---AKH 23173
Query: 1038 GEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQ 1093
E+W S +S++ + +L Y FR+ VN G S P + I + L
Sbjct: 23174 SEKW------SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV 23227
Query: 1094 APPDMAPA--NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV 1151
PD+ PA + S++ + + E+ +G P+ I +++ K + +
Sbjct: 23228 IEPDVKPAFSSYSVQVGQDLKI--------EVPISGRPKPT---ITWTKDGLPLKQTTRI 23276
Query: 1152 -VQDRVE-RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
V D ++ +I++ + + + N +G S +V + P GP +
Sbjct: 23277 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD-PPKGPVKFDDV 23335
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW-LVEGNSSRSA-QLTGLG 1267
++ S+ + W+ P G + ++ K DT W +V +R+ ++T L
Sbjct: 23336 --SAESITLSWN--PPLYTGGCQITNYIVQKR---DTTTTVWDVVSATVARTTLKVTKLK 23388
Query: 1268 KYVLYEVQVLAFTRIGDG-SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAA 1326
Y+ ++ A R G + PI+ + PGPP + S+ + W P
Sbjct: 23389 TGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVN 23448
Query: 1327 PNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGE 1385
G ++ Y + + + T + + Q+ A L+ Y FR+ A+ G G+
Sbjct: 23449 NGGSPVIGYHLERKERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGK 23507
Query: 1386 AAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTREL 1442
A++ V + D P P MV++ + + L W +P DG S + Y ++ R+L
Sbjct: 23508 ASKNSECYVARDPCDPPGTPEPIMVKRNE-----ITLQWTKPVYDGGSMITGYIVEKRDL 23562
Query: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
P GRW + ++ + + F V L Y+FRV A N G S+ S+S + A +
Sbjct: 23563 PDGRW-MKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG--AISKPSDSTGPITAKDE 23619
Query: 1503 EAPTILSVTPHTTTSVLIRWQPP--AEDKINGILLGFRIRYRELLYEGLRG-FTLRGINN 1559
+S+ P ++++ E ++G L E LRG +
Sbjct: 23620 VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP--------TIEWLRGDKEIEESAR 23671
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYEL--DNLNKHRRYEIRMSVYNAVG--EGPSSPPQE 1615
+ ++ +++ R QY L N+ + + + + V + G EGP
Sbjct: 23672 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP------ 23725
Query: 1616 VFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERV 1675
V V G T+ + +TW PPL DI Y + E R L V
Sbjct: 23726 --------------VQVTGVTSEKCSLTWS-PPLQDGGSDISHYVVEKRETSR--LAWTV 23768
Query: 1676 KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFS 1733
+ NS+K+ L Y+ + A N G G S P + P P S++ +
Sbjct: 23769 VASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 23828
Query: 1734 ELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLA 1792
+ S+ V W P G + GY + S + + + + + + L L+V L
Sbjct: 23829 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGI----RWIKCNKRRITDLRLRVTGLT 23884
Query: 1793 EGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPP-GVPIIVRYSSAIAIHWSSGD 1848
E Y FR+ A+ G A V + PGPP I+ ++I + W G
Sbjct: 23885 EDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW--GK 23942
Query: 1849 P---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
P G I YV+E +DE W I+ V+ + S L Y RV A+N
Sbjct: 23943 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISK--LTEHQEYKIRVCALNK 24000
Query: 1906 YGFGTPSS-PSQSVPAQK 1922
G G +S P P K
Sbjct: 24001 VGLGEATSVPGTVKPEDK 24018
Score = 202 bits (515), Expect = 2e-51
Identities = 431/1978 (21%), Positives = 725/1978 (36%), Gaps = 286/1978 (14%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGAL----------LQRQTEVQ--VAYMGSFEEGEK 120
E +Y +T L +R I RN +G + + R V V + + +G
Sbjct: 27910 ECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDG-- 27967
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT--LENTLVILSTVAPDA 178
+ GE+ I+A + P P+VTWF+DG +I + IT L +T + + D
Sbjct: 27968 -LIIKSGESLRIKA-LVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDH 28025
Query: 179 GRYYVQAVNDKNGDNKTSQPITL--TVENVGGPA-------------------DPIAPTI 217
Y + +G K + + T V GP D AP
Sbjct: 28026 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 28085
Query: 218 --IIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPT 275
II + TS +A + +C A + IKL +G +S N+ + P
Sbjct: 28086 HYIIEKRETSRLAWAL-IEDKCEAQSYTAIKLI-----NGNEYQFRVSAVNK-FGVGRPL 28138
Query: 276 GSDAGYYECEAVLRSSS---VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQA 332
SD + + + + PS + G +++ PE +E+++ + +
Sbjct: 28139 DSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA-----RPESDGGSEIQQYILERREK 28193
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
K S W K + + + TRF+ ++GL + F A NAAG S
Sbjct: 28194 K-----STRWVKVISKRPISE-TRFK--------VTGLTEGNEYEFHVMAENAAGVGPAS 28239
Query: 393 ------------------TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
T + VT + V DG ++
Sbjct: 28240 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 28299
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGV-DEASADLVVW 493
W K + A V+ R+T ++ + + A N G D +
Sbjct: 28300 WHK---VNAEACVKT-RYT--------VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIK 28347
Query: 494 ARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR 547
A R+T P D Q+ + AS+ + + R T +W K + L +
Sbjct: 28348 AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT 28407
Query: 548 LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRA 607
D +L + D G YT V + G+ S + ++V P P P+ T V R +
Sbjct: 28408 -DSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTP-GPPGPI-TFKDVTRGS 28464
Query: 608 INLTWTKPF-DGNSPLIRYILEMSE-NNAPWTVLLASVDPKATS--VTVKGLVPARSYQF 663
L W P DG + + Y++E E + W V + K T V L Y F
Sbjct: 28465 ATLMWDAPLLDGGARIHHYVVEKREASRRSWQV----ISEKCTRQIFKVNDLAEGVPYYF 28520
Query: 664 RLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI- 722
R+ AVN+ G G+ + E + E+P APP+ + + S ++ W P H G
Sbjct: 28521 RVSAVNEYGVGEPYEMPEPIVATEQP--APPRRLDVVDTSKSSAVLAWLKP--DHDGGSR 28576
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG----VY 778
+ GY++ G + + +E L+ T YE V A N AG +
Sbjct: 28577 ITGYLLEMRQKGSDFWVEAGHTKQL---TFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 28633
Query: 779 SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG-------YKLIA 831
SS + + P + P A+ T T T A SP I+ G +KL
Sbjct: 28634 SSVIIK-----EPQIEPT---ADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEE 28685
Query: 832 WEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH 891
++ + V++ T + ++ + YF ++ T G S +V
Sbjct: 28686 MRLKETDRVSITTTKDRTTLTVKDSMRGDSGR---YFLTLE--NTAGVKTFSVTVVVIGR 28740
Query: 892 EDVPGPV-GHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNV 949
PGPV G + S + S +SW EP + G +T Y + E T ++ +
Sbjct: 28741 ---PGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKR 28797
Query: 950 TLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNIGPRS 1008
T + +VT LT Y+ V++ G + + ++ I + P P PT + ++ +
Sbjct: 28798 T-QIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANA 28856
Query: 1009 VTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
+++++ P +DG + I + VE + E L + + + +V L Y
Sbjct: 28857 MSIRWEEPYHDGGSKIIGYWVEKK-----ERNTILWVKENKVPCLECNYKVTGLVEGLEY 28911
Query: 1068 SFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
FR +N G S S+ SR I Q P D AP + + +++ L W Y+G
Sbjct: 28912 QFRTYALNAAGVSKASEASRPIMA-QNPVD-APGRPEVTDVTRSTVSLIWSA---PAYDG 28966
Query: 1128 NPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGP 1185
+ VGY I K G G+ L + +T+ L E Y +V A NA G
Sbjct: 28967 GSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG--- 29023
Query: 1186 WSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD 1245
V+ + ES + A + V + LVL V K
Sbjct: 29024 ----VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKP---- 29075
Query: 1246 TQPRFWLVEGNSSR------SAQLTGL--------------GKYVLYEVQVLAFTRIGDG 1285
+P+ +G+ S Q TG GKY L +
Sbjct: 29076 -EPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS-- 29132
Query: 1286 SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTA 1345
++ + LD PGP + V L W P G + + I R T+
Sbjct: 29133 ------VMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 29185
Query: 1346 NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEKRDRPQPPS 1404
N VE P+ Y T L + Y+FR+ A + G G E+ +V P PP
Sbjct: 29186 NWVIVEGECPTL-SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPG 29244
Query: 1405 RPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
P ++ +++ W +P SDG + + Y + RE S RW + + V
Sbjct: 29245 IP--EEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKV 29302
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVTPHTTTSVL 1519
L Y+FRV A N G+SE SE S ++ + + P AP ++ T H S+
Sbjct: 29303 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKH---SIS 29359
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
+ W P D I+ G+ L W + + ++RN
Sbjct: 29360 LAWTKPMYDGGTDIV----------------GYVLEMQEKDTDQWYRVHTNATIRN---- 29399
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSS-------PPQEVFVGE-AVPTAAPRNVV 1631
T++ + +L ++Y R++ N G S P + + + + + + V
Sbjct: 29400 --TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVT 29457
Query: 1632 VHGATATQL--DVTWEPPPL---DSQNGDIQGYKIY-FWEAQRGNLTERVKTLFLAENSV 1685
+ + +L V+ PPP+ Q D+ I E+ + ++V + ++
Sbjct: 29458 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTI 29517
Query: 1686 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
+ +N +G + V V ++ G P SVK E++ SV ++WE
Sbjct: 29518 EAENQSGKKSATVLVKVYDTPGPCP------------------SVKVKEVSRDSVTITWE 29559
Query: 1746 APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1805
P G +V + + + TV K + L+ ++ L EG Y FR+ +
Sbjct: 29560 IPTIDGGAPVNNYIVEKREA---AMRAFKTVTTKCSKTLY-RISGLVEGTMYYFRVLPEN 29615
Query: 1806 -FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARP 1863
+ G E + E P + ++ S + + W G +T YV+EA
Sbjct: 29616 IYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK 29675
Query: 1864 SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
+ W +K + + + ++ L G Y FR+ A N+ G P +V Q
Sbjct: 29676 AGTERW---MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 29730
Score = 201 bits (512), Expect = 5e-51
Identities = 369/1646 (22%), Positives = 603/1646 (36%), Gaps = 237/1646 (14%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVIDGMS----- 418
++ LV F+ A+N AG + + T I + P LD T+ DG++
Sbjct: 20335 VTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGD 20394
Query: 419 --VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ A G P P +W K + + + TP S L I DAG YT
Sbjct: 20395 TIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSS-MLTIKYATRKDAGEYTIT 20453
Query: 477 ATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVTHDPRV 525
ATN G + V I+ +++ + T S + + R
Sbjct: 20454 ATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRE 20513
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRS 581
T R +W + + H +L + Y RV + G +S
Sbjct: 20514 TSRLLWTVVSEDIQSCRHVATKLIQGNE-------------YIFRVSAVNHYGKGEPVQS 20560
Query: 582 AHLRVRQL---PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWT 637
+++ P PE P +S V + ++W +P D G S + Y +E E +
Sbjct: 20561 EPVKMVDRFGPPGPPEKP--EVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRW 20618
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQN 696
V V GL +Y+FR+ A N G G S+ ++ V + + P PP N
Sbjct: 20619 VRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 20678
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILK--GYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
+ T +S + W P H +G L+ GY++ + G + T + ++
Sbjct: 20679 PHVTDTTKKSASLAWGKP---HYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVV 20735
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
DL Y ++A N AG+G + + + + P + AE + +R
Sbjct: 20736 PDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVEREMAPDFELDAELRRTLVVR----- 20789
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
G + + P + VT +D+I++ + ++ TE FT ++
Sbjct: 20790 ----------AGLSIRIFVPIKGRPAPEVTWT---KDNINLKNRANIEN-TESFTLLII- 20834
Query: 875 TTPGDGPRSTPQLVRTHE---------------DVPGPVGHLSFSEILDTSLKVSWQEPG 919
P T + V T E D PGPV +L ++I S+ + W P
Sbjct: 20835 --PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPL 20892
Query: 920 EKNGI-LTGYRISWEEYNR----TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
G +T Y + E R T T H Y+VTGL+ Y V A
Sbjct: 20893 IDGGSRITNYIVEKREATRKSYSTATTKCH-----KCTYKVTGLSEGCEYFFRVMAENEY 20947
Query: 975 GQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVG 1033
G G+ + +T E P PP +L I +I +V+L + +P +DG + I+ +++EAQ
Sbjct: 20948 GIGEPTETT-EPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRK 21006
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
++W I + V +L Y+F++ VN G S
Sbjct: 21007 ---GSDQWTHITTVKG----LECVVRNLTEGEEYTFQVMAVNSAGRS------------- 21046
Query: 1094 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESV-------GYKIKYSRSDGHGK 1146
AP + P V +T LPE++ G + + K++
Sbjct: 21047 APRESRPVIVKEQTM-----------LPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKP 21095
Query: 1147 TLSHVVQDRVERDYTIEDLEEW-TEYRVQVQAFNAIGSGPWSQT---VVGRTRESV---- 1198
T++ D++ + + E T + + SGP+ T +VG + +
Sbjct: 21096 TVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQV 21155
Query: 1199 -----PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV 1253
P +GP ++ S + W + PE D + Y V ++ DS T
Sbjct: 21156 HDIPGPPTGPIKFDEVS--SDFVTFSW-DPPENDGGVPISNYVVEMRQTDSTTWVELATT 21212
Query: 1254 EGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEV 1312
++ A T L + Y+ +V A R G G + I+ VPGPP V
Sbjct: 21213 VIRTTYKA--TRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAV 21270
Query: 1313 RTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY 1371
S+ + W P + G IL Y + + + L P + ++GL Y
Sbjct: 21271 TKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPG-NIFKSSGLTDGIAY 21329
Query: 1372 LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE-----------DVRARSVLL 1420
FR+ A+ G + +P PS PM+ + ++ +V L
Sbjct: 21330 EFRVIAENMAG--------------KSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTL 21375
Query: 1421 SW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKAT 1479
W +P G + Y ++ R+LP+GRW + S + + F V L +Y+FRV A
Sbjct: 21376 KWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFS-NILENEFTVSGLTEDAAYEFRVIAK 21434
Query: 1480 NDIGD-SEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFR 1538
N G S SE S+++T EAP I T +L + FR
Sbjct: 21435 NAAGAISPPSEPSDAITCRDDV--EAPKIKVDVKFKDTVILKAGE------------AFR 21480
Query: 1539 IRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIR 1598
+ + G P W++ + + + +NK
Sbjct: 21481 LEA-----------DVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRR-D 21528
Query: 1599 MSVYNAVGEGPSSPPQEVFVGEAVPTAAPRN--VVVHGATATQLDVTWEPPPLDSQNGDI 1656
Y P + +F + + P + V T+ + ++W PP LD I
Sbjct: 21529 SGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPP-LDDGGAKI 21587
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
Y + E R T + + + +K+ L Y+ V A N G G S P
Sbjct: 21588 DHYIVQKRETSRLAWTNVASEVQVTK--LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 21645
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIV 1774
P P + + + +T S+ V W P G E + E + +
Sbjct: 21646 VLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS-EIINYIVERRDKAG--QRWI 21702
Query: 1775 TVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGA------PGPP 1828
+ K + L KV L EG Y FRI A+ I A T P A PGPP
Sbjct: 21703 KCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN---AAGISAPSPTSPFYKACDTVFKPGPP 21759
Query: 1829 GVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 1886
G P ++ S S+I+I W+ G IT Y++E +E W I+ + +SYT +
Sbjct: 21760 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 21819
Query: 1887 MDILKPGVSYDFRVIAVNDYGFGTPS 1912
L Y R+ A+N G G P+
Sbjct: 21820 G--LTENQEYKIRIYAMNSEGLGEPA 21843
Score = 201 bits (510), Expect = 8e-51
Identities = 370/1602 (23%), Positives = 611/1602 (38%), Gaps = 215/1602 (13%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G +V L G P P ++W+K +L + +L + + D+G
Sbjct: 19306 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLCTLELFSVNRKDSG 19364
Query: 472 TYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVT 520
YT A NS G A+ L V A +I K D++++ S +
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424
Query: 521 HDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
D R T R W + AT+ S +L C G D
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFR----------ICAENKYGVGDPV 19474
Query: 581 SAHLRVRQLPHAP----EHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP 635
+ + P+ P + PV +S + + + ++W P D G SP+ Y+LE E A
Sbjct: 19475 FTEPAIAKNPYDPPGRCDPPV--ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAV 19532
Query: 636 -WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP--PTA 692
WT + + T + GL Y+FR+ A+N G G+ S D + + +P P
Sbjct: 19533 NWTKVNRKPIIERT-LKATGLQEGTEYEFRVTAINKAGPGKPS-DASKAAYARDPQYPPG 19590
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIR--------YCLAGLPVGYQFKNI 744
PP T S+ + W P + I+ GY++ + LP Q
Sbjct: 19591 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPII-GYLVEVKRADSDNWVRCNLPQNLQK--- 19646
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T +V L+ ED T Y+ V A N G S + + + P G + A+
Sbjct: 19647 TRFEVTGLM-ED----TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 19701
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT-ARPNFQDSIHVGFVSGLKK 863
+ +R G + + P + +T ++PN +G K
Sbjct: 19702 TLILR---------------AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDI---K 19743
Query: 864 FTEYFTSVLC------------FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
T++ T + C T + +V D PGP +++ EI S
Sbjct: 19744 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 19803
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
V+W+ P G + Y + + R + + T +RV L +Y V A
Sbjct: 19804 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT-SFRVANLEEGKSYFFRVFA 19862
Query: 971 MTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVE 1029
G G T + + PGP +L + ++ S ++ ++ P DG + I ++V+
Sbjct: 19863 ENEYGIGD-PGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 19921
Query: 1030 AQVGVVGEGEEWL-LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
+ E +W ++ LS + A+ DL Y+FR+ N G PS+
Sbjct: 19922 ----FLTEENKWQRVMKSLSLQYSAK-----DLTEGKEYTFRVSAENENGEGTPSEI--- 19969
Query: 1089 IQTLQAPPDMAPANVSLR-------TASETSLW-----LRWMPLPEMEYNGNPESVGYKI 1136
T+ A D+ ++ L+ A E S + ++ P P + + + +
Sbjct: 19970 --TVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT 20027
Query: 1137 KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGS--GPWSQTVVGRT 1194
+ S V V + D ++ + + N G+ G S VVG+
Sbjct: 20028 RVS-----------VESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 20076
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE 1254
+P+ GP + T+ +M ++W+ P+ D + Y + +++DS
Sbjct: 20077 --GIPT-GPIKFDEV--TAEAMTLKWAP-PKDDGGSEITNY--ILEKRDSVNNKWVTCAS 20128
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTR--IGDGSPSHPPILERTLD--DVPGPPMGILFP 1310
+ ++T L + + Y +V A + +G+G S P + D D P PP +
Sbjct: 20129 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV--- 20185
Query: 1311 EVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTT----ANTATVEVLAPSARQYTATGL 1365
+VR SV L W P G I Y + + + AN + + R + TGL
Sbjct: 20186 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM-----RDFKVTGL 20240
Query: 1366 KPESVYLFRITAQTRKGWGEAA---EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW 1422
Y FR+ A G G+ + E +V D PP +P V ++ SV L W
Sbjct: 20241 TEGLEYEFRVMAINLAGVGKPSLPSEPVVAL----DPIDPPGKPEVI--NITRNSVTLIW 20294
Query: 1423 -EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND 1481
EP DG + Y ++ R+LPS W + + V+ +F V L Y+FR++A N
Sbjct: 20295 TEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 20353
Query: 1482 IGDSEFSEESESLTTLQAAPD-EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIR 1540
G S SES T+ + EAPTI+ P +D G I+
Sbjct: 20354 AG--AISAPSESTETIICKDEYEAPTIVL-------------DPTIKD-------GLTIK 20391
Query: 1541 YRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL----SRPSLTQYELDNLNKHRRYE 1596
+ + L ++ G P ++W++ ++ S P+ + + + E
Sbjct: 20392 AGDTIV--LNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 20449
Query: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
++ N G + + V V P V + +A + +TW PP L+ I
Sbjct: 20450 YTITATNPFG----TKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP-LEDGGSPI 20504
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
+ Y + E R L V + V K + G Y+ V+A N G G +S P
Sbjct: 20505 KSYILEKRETSR-LLWTVVSEDIQSCRHVATKLIQG-NEYIFRVSAVNHYGKGEPVQSEP 20562
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKI 1773
+ + P P + S +T + VSW+ P G + GY + + V I
Sbjct: 20563 VKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAI 20622
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPPGV 1830
T S L KV L EG TY FR+ A+ GP EA+ + + A PGPP
Sbjct: 20623 KTPV----SDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 20678
Query: 1831 PIIVRYSSAIA-IHWSSGDPGKG-PITRYVIEARPSDEGLWDILIKDIPKEVSSYT-FSM 1887
P + + A + W G IT YV+E + + W IKD T F +
Sbjct: 20679 PHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVV 20735
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPS-SPSQSVPAQKANPFYE 1928
L+ Y+FR+ A+ND G G P+ P + ++ P +E
Sbjct: 20736 PDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFE 20777
Score = 200 bits (508), Expect = 1e-50
Identities = 369/1617 (22%), Positives = 631/1617 (39%), Gaps = 210/1617 (12%)
Query: 477 ATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
A N+ GV + SA + R PP + V +GT ++V + P T+ W
Sbjct: 16093 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLT--W 16150
Query: 532 EKDGATLGTESHP--------RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
K P ++ +D +L I Q+ D G YT ++ G S+
Sbjct: 16151 FKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 16210
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
L V P P P+ +V + L+W P D G S + Y++E E N V ++S
Sbjct: 16211 LNVLGRPGPPVGPIK-FESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSS 16269
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--------PP 694
+PK + T+ L+ Y FR+ A N G G+ L EP TA P
Sbjct: 16270 -EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE--------PLDSEPETARNLFSVPGAP 16320
Query: 695 QNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
S T S+ + W+ P E + GY + ++K + + + L
Sbjct: 16321 DKPTVSSVTRNSMTVNWEEP-EYDGGSPVTGYWLEMKDT---TSKRWKRVNRDPIKAMTL 16376
Query: 755 ------EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST-- 806
LI ++Y+ V A N+AG+G S T + P PPG + T+ T
Sbjct: 16377 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD-PIAPPGPPFPKVTDWTKS 16435
Query: 807 TIRFTWNAP---SPQFINGINQGYKLIA---WEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ W+ P + G YK WE +++EV V+G
Sbjct: 16436 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL-----------VVTG 16484
Query: 861 LKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP- 918
LK+ Y V G G P ++ + + P D L S ++
Sbjct: 16485 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP----------DLQLDASVRDRI 16534
Query: 919 -GEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVT-GLTALTTYTI---------E 967
G++ RI + VT + TL T TA+++ +
Sbjct: 16535 VVHAGGVI---RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQG 16591
Query: 968 VAAMTSKGQGQVSASTISSGVPPELPGPP-TNLGISNIGPRSVTLQ-FRPGYDGKTSISR 1025
V ++ +K + TI V ++PGP T N+ S L F P DG + I+
Sbjct: 16592 VYSLLAKNEAGERKKTIIVDVL-DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITN 16650
Query: 1026 WLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 1085
+++E + + W + +A V L Y FR+ N +G P +
Sbjct: 16651 YVIEKRES---DRRAWTPVTYTVTRQNAT---VQGLIQGKAYFFRIAAENSIGMGPFVET 16704
Query: 1086 SRKIQTLQAPPDMA--PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG 1143
S + ++ P + P ++ ++ ++ ++ L W P +Y+G E + Y ++ SR G
Sbjct: 16705 SEAL-VIREPITVPERPEDLEVKEVTKNTVTLTWNP---PKYDGGSEIINYVLE-SRLIG 16759
Query: 1144 HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRESVPS 1200
K + + R YT++ L+E Y +V A N +G G S + + + + P+
Sbjct: 16760 TEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPT 16819
Query: 1201 ---SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS-DTQPRFWLVEGN 1256
++ + ++ R+S P+ + V+ ++ T P +E
Sbjct: 16820 LHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALE-- 16877
Query: 1257 SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTT 1315
A+ + GKY + + + + S + + D PGPP+G + F EV
Sbjct: 16878 -KIKAKRSDSGKYCVV---------VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927
Query: 1316 SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV-YLFR 1374
+ + W+PP G + I + + V + SA+ E Y+FR
Sbjct: 16928 YMVISWKPPLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKLLEGKDYIFR 16985
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
I A+ G + + + + R R P P +P+V + V S L++W DG P+
Sbjct: 16986 IHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE--VTKDSALVTWNKPHDGGKPIT 17043
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESES 1493
Y ++ RE S RWA + H + F V L Y+FRV A N+IG + S S+
Sbjct: 17044 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 17103
Query: 1494 LTTLQAAPDEAPTILSVTPHTT-TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGF 1552
+ +P + TT SV + WQPP D +LG+ + Y+++ E R
Sbjct: 17104 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG-GSKILGYIVEYQKVGDEEWR-- 17160
Query: 1553 TLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSS 1611
R + P S P T+Y++ L + Y+ R+ NA GE P+
Sbjct: 17161 --RANHTPE---------------SCPE-TKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 17202
Query: 1612 PPQEVFVGEAVPTAAPRNVVVHGATATQLDV-TWEPPPLDSQNGDIQGYKIYFWEAQRGN 1670
P+ V V + + P +++ A + + + L + + K+ + + R
Sbjct: 17203 VPEPVLVKDRL---EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA 17259
Query: 1671 LTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSV 1730
T+ + + ++++N + S+ N AG T + P P +
Sbjct: 17260 PTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGS---KTVSVKVLVLDKPGPPRDL 17316
Query: 1731 KFSELTTTSVNVSWEAP------QFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPL 1784
+ SE+ S ++W+ P N ++E + SP+ SK K +
Sbjct: 17317 EVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSK-----KKSHF-- 17369
Query: 1785 WLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAP--GPPGVPIIVRY----S 1837
K L EG Y FR+ A+ + GP +E T P + PPG P + +
Sbjct: 17370 ---AKHLNEGNQYLFRVAAENQYGRGPFVE---TPKPIKALDPLHPPGPPKDLHHVDVDK 17423
Query: 1838 SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSY 1896
+ +++ W+ D G PIT Y++E + +EG D + K V++ + L+ G +Y
Sbjct: 17424 TEVSLVWNKPDRDGGSPITGYLVEYQ--EEGTQDWIKF---KTVTNLECVVTGLQQGKTY 17478
Query: 1897 DFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEEWWFLVVIALVGLIFI--LLLVFVLIIR 1954
FRV A N G G P + ++P + L V + GL+ + F IIR
Sbjct: 17479 RFRVKAENIVGLGLPDT---TIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIR 17535
Query: 1955 GQSKKYAKKTDSGNSAKSGALGHSEMMSLDESSFPALELNNRRLSVKNSFCRKNGLY 2011
G AK T G+ K+ E +++ +F ++ L++KN R G Y
Sbjct: 17536 GVPVPTAKWTTDGSEIKT-----DEHYTVETDNFSSV------LTIKNCLRRDTGEY 17581
Score = 200 bits (508), Expect = 1e-50
Identities = 379/1720 (22%), Positives = 629/1720 (36%), Gaps = 216/1720 (12%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT-LENTLVILSTVAPDAGRYY 182
V H + ++ P P VTW + R +P + I T + +++VI + G Y
Sbjct: 16535 VVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYS 16594
Query: 183 VQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANAR 242
+ A N+ KT I + V +V GP T + T+ + + E +
Sbjct: 16595 LLAKNEAGERKKT---IIVDVLDVPGPVG----TPFLAHNLTNESCKLTWFSPE--DDGG 16645
Query: 243 PLIKLHIIWKKDG---VLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG 299
I ++I K++ + + T+ A ++ A P V
Sbjct: 16646 SPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETS 16705
Query: 300 AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPP------PSITWYKDAAVVEVEK 353
L + EP + PER E+++V PP I + ++ ++ EK
Sbjct: 16706 EALVIREP---ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 16762
Query: 354 LTRFRQRN--DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL-- 409
+ N + GL DT ++ A N G+ + S + + L
Sbjct: 16763 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 16822
Query: 410 ----DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
T+ G + L SG P+P ++W K E + + TP I
Sbjct: 16823 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 16882
Query: 466 HISDAGTYTCLATNSRG----------------------VDEASADLVVWARTRITKPPQ 503
SD+G Y + NS G DE + D +V + KPP
Sbjct: 16883 R-SDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVIS----WKPPL 16937
Query: 504 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
D S + + + + +W + ++ ++ G +I + + +
Sbjct: 16938 DDG------GSKITNYIIEKKEVGKDVW-MPVTSASAKTTCKVSKLLEGKDYIFRIHAEN 16990
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLI 623
+ + ++S DS A R R +P AP+ P+ T V + + +TW KP DG P+
Sbjct: 16991 LYGISDPLVS----DSMKAKDRFR-VPDAPDQPIVT--EVTKDSALVTWNKPHDGGKPIT 17043
Query: 624 RYILEMSEN-NAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
YILE E + W + T V L+ Y+FR+ A N++G G S ++
Sbjct: 17044 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 17103
Query: 683 VSLPEE-PPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQF 741
V + +PP N A T S+ + WQPP + IL GYI+ Y G +
Sbjct: 17104 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKIL-GYIVEYQKVGDEEWRRA 17162
Query: 742 KNITDA-DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV-H 799
+ ++ + L Y+ V A N+AG + V E L PP +
Sbjct: 17163 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES-DPAHVPEPVLVKDRLEPPELILD 17221
Query: 800 AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS 859
A I+ I G+ + + W+ E + T D VG
Sbjct: 17222 ANMAREQHIKVGDTLRLSAIIKGV--PFPKVTWKKEDRDAPTKARI-----DVTPVGSKL 17274
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
++ + T T + D PGP L SEI S ++W+EP
Sbjct: 17275 EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL 17334
Query: 920 EKNG-ILTGYRI--------SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
+ G ++T Y + W + T+ + +H+ + L Y VAA
Sbjct: 17335 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH---------LNEGNQYLFRVAA 17385
Query: 971 MTSKGQGQV--SASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWL 1027
G+G + I + P PGPP +L ++ V+L + +P DG + I+ +L
Sbjct: 17386 ENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYL 17445
Query: 1028 VEAQVGVVGEG-EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS-PPSQP 1085
VE Q EG ++W+ ++N V L Y FR++ NIVG P +
Sbjct: 17446 VEYQ----EEGTQDWIKFKTVTN----LECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI 17497
Query: 1086 SRKIQTLQAPPD-------MAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY 1138
+ Q PP + V T +R +P+P ++ + +
Sbjct: 17498 PIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI------ 17551
Query: 1139 SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESV 1198
++D H V D TI++ Q+ NA GS V T V
Sbjct: 17552 -KTDEH----YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGS---KTVAVHLTVLDV 17603
Query: 1199 PS--SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV--E 1254
P +GP N+ L T M + W + P+ D V+ Y V + DT+ W V
Sbjct: 17604 PGPPTGPINI--LDVTPEHMTISW-QPPKDDGGSPVINYIV----EKQDTRKDTWGVVSS 17656
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVR 1313
G+S ++ L K Y +V A +IG G P P + + P PP + ++
Sbjct: 17657 GSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDIT 17716
Query: 1314 TTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+ + W P + G I Y + R T V + ++ TGL + Y
Sbjct: 17717 ENAATVSWTLPKSDGGSPITGYYMERR--EVTGKWVRVNKTPIADLKFRVTGLYEGNTYE 17774
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLS 1430
FR+ A+ G + + + + P PP P ++ + R + L+ +P SDG S
Sbjct: 17775 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS-RETADLVWTKPLSDGGS 17833
Query: 1431 PVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
P+ Y ++ ++ + +W + +F V L Y+FR+KA N +G+ E E
Sbjct: 17834 PILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 17893
Query: 1491 SESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLR 1550
+ES+ A IL P V R + + +G IR
Sbjct: 17894 AESVI--------AKDILH-PPEVELDVTCR-------DVITVRVGQTIRILA------- 17930
Query: 1551 GFTLRGINNPGATWAELTSMY-------SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
++G P TW + + +++L R L E + H +Y I S N
Sbjct: 17931 --RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRAD-HGKYII--SAKN 17985
Query: 1604 AVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF 1663
+ G S V +N+ V T ++WE PLD+ +I + + +
Sbjct: 17986 SSGHAQGS----AIVNVLDRPGPCQNLKVTNVTKENCTISWE-NPLDNGGSEITNFIVEY 18040
Query: 1664 -------WEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP---RS 1712
W ++T+R +K LA N Y V A N G GP
Sbjct: 18041 RKPNQKGWSIVASDVTKRLIKANLLANNE-----------YYFRVCAENKVGVGPTIETK 18089
Query: 1713 TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
TP P P ++ ++ T V + W P + G
Sbjct: 18090 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGG 18129
Score = 198 bits (503), Expect = 5e-50
Identities = 328/1450 (22%), Positives = 557/1450 (38%), Gaps = 178/1450 (12%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSA 582
P+VT W K G +D L I + D G Y+ +++ G +
Sbjct: 18636 PKVT----WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 18691
Query: 583 HLRVRQLPHAPEHPVATL--STVERRAINLTWTKPF-DGNSPLIRYILEMSE-NNAPWTV 638
++RV P PV+ L S V + + +++W P DG S + YI+E E + W+
Sbjct: 18692 NVRVLDTPG----PVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWST 18747
Query: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--PPQN 696
+ V K TS V LVP Y FR+ AVN+ G G D + L +P + PP+
Sbjct: 18748 VTPEV--KKTSFHVTNLVPGNEYYFRVTAVNEYGPG-VPTDVPKPVLASDPLSEPDPPRK 18804
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED 756
+ + T S + W PP + GYI Y P + D+ +L++
Sbjct: 18805 LEVTEMTKNSATLAWLPPLRD-GGAKIDGYITSYREEEQPADRWTEYSVVKDL-SLVVTG 18862
Query: 757 LIIWTNYEIEVAAYNSAGL-------GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIR 809
L Y+ VAA N+ G+ GVY +K L + P + +A I
Sbjct: 18863 LKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE---QLLPPKILMPEQITIKAGKKLRIE 18919
Query: 810 -FTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYF 868
+ P P W+ ++E VT + DS + + + + +
Sbjct: 18920 AHVYGKPHP-----------TCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 18968
Query: 869 TSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
S+ + G + +V D PG P S+I + +SW P E G +T
Sbjct: 18969 YSLTAENSSGTDTQKIKVVVM---DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 19025
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTIS 985
Y + + +R + VT RV L Y V A G + +++ +
Sbjct: 19026 NYIVEKCDVSRGDW-VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 19084
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLI 1044
+ P +P P N ++ + + + + RP DG + I +L+E + E L+
Sbjct: 19085 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK-------ERNSLL 19137
Query: 1045 HQLSNEPDARSMEVP--DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQT-LQAPPDMAPA 1101
+N+ RS E P L YSFR+ +N G+SPPS+P+ + + P P
Sbjct: 19138 WVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE 19197
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
+ + ++ + +W R +++G + +GY ++ + G + ++ + +Y
Sbjct: 19198 VIDVTKSTVSLIWAR------PKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 19251
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRW 1220
T LEE +Y+ + A A+ P S+ T + + P + S + V+
Sbjct: 19252 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPVT--ILAENVPPRIDLSVAMKSLLTVKA 19309
Query: 1221 SEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLG-KYVLYEVQVLAF 1279
+ L V K + + W +G + A+ + + L +++ +
Sbjct: 19310 G-------TNVCLDATVFGKPMPTVS----WKKDGTLLKPAEGIKMAMQRNLCTLELFSV 19358
Query: 1280 TRIGDG---------SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
R G S S ++ + D PGPP + ++ + L W+PP G
Sbjct: 19359 NRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS 19418
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA-EA 1389
+ I + T+ N A V P + L Y FRI A+ + G G+
Sbjct: 19419 EITNYIVDKRETSRPNWAQVSATVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTE 19477
Query: 1390 LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWA 1448
+ D P P++ ++ + +SW+ P DG SP+ Y ++ RE + W
Sbjct: 19478 PAIAKNPYDPPGRCDPPVI--SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWT 19535
Query: 1449 LHSASVSHNASSFIVDR------LKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-P 1501
+ I++R L+ T Y+FRV A N G + S+ S++ P
Sbjct: 19536 KVNRKP-------IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYP 19588
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
P V T +SV + W PA D + I+ G+ +
Sbjct: 19589 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPII----------------GYLVEVKRADS 19632
Query: 1562 ATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG-EGPSSPPQE----- 1615
W +++ T++E+ L + +Y+ R+ N +G PS P +
Sbjct: 19633 DNWVRCNLPQNLQK------TRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 19686
Query: 1616 -VFVGEAVPTAAPRNVVVHGATATQ---LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL 1671
+ E A R ++ A T + V PPP KI W NL
Sbjct: 19687 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPP-----------KI-TWSKPNVNL 19734
Query: 1672 TERV-----KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSA 1726
+R+ T F + ++ +N+ Y A + N+ G + T P
Sbjct: 19735 RDRIGLDIKSTDF--DTFLRCENVNKYDAGKYILTLENSCG---KKEYTIVVKVLDTPGP 19789
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P +V E++ S V+WE P G +V + + S + T K +
Sbjct: 19790 PVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTS----F 19845
Query: 1787 KVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAPGPPGVPIIVR--YSSAIAIH 1843
+V +L EG +Y FR+ A+ + G E + PGP V + VR S+ +I
Sbjct: 19846 RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQ-TPGPV-VDLKVRSVSKSSCSIG 19903
Query: 1844 WSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
W G I YV++ ++E W ++K + S +S L G Y FRV A
Sbjct: 19904 WKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-----SLQYSAKDLTEGKEYTFRVSA 19957
Query: 1903 VNDYGFGTPS 1912
N+ G GTPS
Sbjct: 19958 ENENGEGTPS 19967
Score = 195 bits (495), Expect = 5e-49
Identities = 428/1972 (21%), Positives = 746/1972 (37%), Gaps = 272/1972 (13%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP 135
++++ L F+R N+ G R+ + V E E +RA
Sbjct: 26432 HVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAG 26491
Query: 136 R-------IASFPQPQVTWFRDGRKIPPSSRI--AITLEN-TLVILSTVAPDAGRYYVQA 185
I+ P P+VT RDG + + R IT EN T+ + +V DAGRY + A
Sbjct: 26492 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 26551
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVA--------GTSEVTLEC 237
N T I + V + GP P P +I SV G S+VT
Sbjct: 26552 ANSSG---TTKAFINIVVLDRPGP--PTGPVVISDITEESVTLKWEPPKYDGGSQVTNYI 26606
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI---------SDHNRRLTIPNPTG-SDAGYYECEAV 287
+ +W + ++ + ++ R+ N G SD C V
Sbjct: 26607 LLKRETSTA---VWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTV 26663
Query: 288 LRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAA 347
+ P +++ + ++ VV + K SI W K
Sbjct: 26664 KLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD--RNSILWQKANK 26721
Query: 348 VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS--------------- 392
+V + T F+ +GL+ + F+ +A NAAG + S
Sbjct: 26722 LVI--RTTHFKVTTIS----AGLIYE----FRVYAENAAGVGKPSHPSEPVLAIDACEPP 26771
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRF 452
+ +T I+ N DG S + P W K F
Sbjct: 26772 RNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS------------F 26819
Query: 453 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV-------VWARTRITKPPQDQ 505
T + +IS + + A N+ G +++V + I P +
Sbjct: 26820 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYT 26879
Query: 506 SVIK---GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWS 561
V+K GT + G++ P TI W KD L T + + + S+ I
Sbjct: 26880 EVVKYRAGTSVKLRAGISGKPAPTIE--WYKDDKELQTNALVCVENTTDLASILIKDADR 26937
Query: 562 GDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNS 620
+ G Y ++ +A G+ S + +++ P P P+ TV I L W P D G +
Sbjct: 26938 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIE-FKTVTAEKITLLWRPPADDGGA 26996
Query: 621 PLIRYILEMSENN-APWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKD 679
+ YI+E E + W+++ ++ +T ++ Y FR+ AVN G G+ +
Sbjct: 26997 KITHYIVEKRETSRVVWSMVSEHLEE--CIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 27054
Query: 680 TERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII----RYCLAGL 735
V+ PP + T S+ + W P + I GY + + L
Sbjct: 27055 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI-SGYFLEKRDKKSLGWF 27113
Query: 736 PVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPP 795
V + T V L ++Y+ V A N+AG G +S +E+ P PP
Sbjct: 27114 KVLKETIRDTRQKVTGLTEN-----SDYQYRVCAVNAAGQGPFSEP-SEFYKAADPIDPP 27167
Query: 796 G---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDS 852
G + + ++I W+ P + + GY ++ +EEE T V+ + + +
Sbjct: 27168 GPPAKIRIADSTKSSITLGWSKPVYDGGSAVT-GY-VVEIRQGEEEEWTTVSTKGEVRTT 27225
Query: 853 IHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEI-LDTS 910
+V VS LK Y+ V G G P + V+ + + P EI LD +
Sbjct: 27226 EYV--VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP-------EIDLDVA 27276
Query: 911 LKVSW-QEPGEKNGILTGYR------ISWEEYNRTNTRVTHY-LPNVTLEYRVTGLTALT 962
L+ S + GE +L ++ ++W + + Y + N +T
Sbjct: 27277 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 27336
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKT 1021
T + G G+ +ST+S V + P L + ++ +VTL + P DG +
Sbjct: 27337 NDTGKYILTIENGVGEPKSSTVSVKVL-DTPAACQKLQVKHVSRGTVTLLWDPPLIDGGS 27395
Query: 1022 SISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +++E + W ++ S++ + S ++ DL+ T + FR+ N +G
Sbjct: 27396 PIINYVIEKRDATK---RTWSVV---SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 27449
Query: 1082 PSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS 1141
P + + ++ + P + ++S++ +++TS+ L W + +++G Y ++ R
Sbjct: 27450 PCETTEPVKAAEVPAPIR--DLSMKDSTKTSVILSWT---KPDFDGGSVITEYVVE--RK 27502
Query: 1142 DGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPS 1200
+T SH + + + L+E + +V A N G S P +
Sbjct: 27503 GKGEQTWSHAGISKT-CEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------VT 27548
Query: 1201 SGPTNVSALATTSSSMLVRWSEVPEAD---RNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
GP V L T V S++P A R G + ++ YK K + WL +G
Sbjct: 27549 IGPITVKELIITPE---VDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSIS--WLKDGLP 27603
Query: 1258 SRSAQLTGLGKY---VLYEVQVLA------FTRIGDGSPSH--PPILERTLDDVPGPPMG 1306
+ ++ K + ++ +T I D + PI TL P
Sbjct: 27604 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 27663
Query: 1307 ILFPEVRTTSVRLIWQPPAAPNG-IILAYQITHRLNTTTANTATVEVLAPSARQ-YTATG 1364
I F E++ SV L W P G I Y I R T+ T V + AR +
Sbjct: 27664 IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR---ETSQTNWKMVCSSVARTTFKVPN 27720
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWE 1423
L ++ Y FR+ A+ R G + + ++ + + R P PP +P++ +V + + L+W+
Sbjct: 27721 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY--NVTSDGMSLTWD 27778
Query: 1424 -PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
P DG S V + ++ +E S W + S + + L Y+FRV A N
Sbjct: 27779 APVYDGGSEVTGFHVEKKERNSILWQKVNTSPI-SGREYRATGLVEGLDYQFRVYAENSA 27837
Query: 1483 GDSEFSEESE-SLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRY 1541
G S S+ S+ +L P P + VT T T ++W PP D + I+ G+ I
Sbjct: 27838 GLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETIT---LKWNPPLRDGGSKIV-GYSIEK 27893
Query: 1542 RELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSV 1601
R+ W N + S QY + L+ RYE R+
Sbjct: 27894 RQ----------------GNERWVRC-------NFTDVSECQYTVTGLSPGDRYEFRIIA 27930
Query: 1602 YNAVGEGPSSPPQE-----VFVGEAVPTAAP------RNVVVHGATATQLDVTWEPPPLD 1650
NAVG SPP + + E VP +++ + ++ + P+
Sbjct: 27931 RNAVGT--ISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVP 27988
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
G +I +R N+ T L S+ +++ T + +V A NA+G
Sbjct: 27989 RVTWFKDGVEI----EKRMNMEI---TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 28041
Query: 1711 RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV 1770
+ Q P ++F+ +T + + W+AP + + C+P+
Sbjct: 28042 AEIKVKVQDTPGKVVGP--IRFTNITGEKMTLWWDAP------------LNDGCAPITHY 28087
Query: 1771 SKIVTVDVKGNSPL-WLKVKDLAE-----------GVTYRFRIRA-KTFTYGPEIEANVT 1817
++ + S L W ++D E G Y+FR+ A F G ++++
Sbjct: 28088 ----IIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPV 28143
Query: 1818 TGPGE-GAPGPPGVPIIVRYS-SAIAIHWSSGDP-GKGPITRYVIEARPSDEGLWDILIK 1874
+ P PG+P + ++I + W+ + G I +Y++E R W +I
Sbjct: 28144 VAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVIS 28203
Query: 1875 DIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQK-ANP 1925
P +S F + L G Y+F V+A N G G S S+ + ++ NP
Sbjct: 28204 KRP--ISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNP 28253
Score = 193 bits (490), Expect = 2e-48
Identities = 350/1604 (21%), Positives = 572/1604 (35%), Gaps = 169/1604 (10%)
Query: 378 FQCFARNAAGEVQTSTYLAVTS---IAPNIT-RGPLDSTVI--DGMSVVLACETSGAPRP 431
F+ A N GE S V +AP++ +G D + + + L G P P
Sbjct: 19953 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 20012
Query: 432 AITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV 491
+++W+KGE LA+ ++ + + +L++ SDAG YT N G E + +
Sbjct: 20013 SVSWKKGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 20071
Query: 492 VWARTRITKPPQDQSVIKGTQASMVCGVTHDP--RVTIRYIWEK----DGATLGTESHPR 545
V + I P + ++ D YI EK + + S +
Sbjct: 20072 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 20131
Query: 546 IRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
R LH ++ + + G +P AP P + V
Sbjct: 20132 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP--PPPNIVDVRH 20189
Query: 606 RAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFR 664
+++LTWT P G SP+ Y LE E N+ + V GL Y+FR
Sbjct: 20190 DSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFR 20249
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEP-----PTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
+ A+N G G + SLP EP P PP T S+ + W P +
Sbjct: 20250 VMAINLAGVG-------KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP--KYD 20300
Query: 720 NG-ILKGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
G L GYI+ LP K N + + DL+ YE + A N+AG
Sbjct: 20301 GGHKLTGYIVE--KRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 20358
Query: 778 YSSKVTEW----------TLQGVPTVPPG-NVHAEATNSTTIRFTWNAPSPQFINGINQG 826
S+ TE T+ PT+ G + A T P P+ + ++
Sbjct: 20359 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPK--SSWSKA 20416
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQ 886
K I + ++T +T+ P + +K T T
Sbjct: 20417 GKDI-----RPSDITQITSTP-------TSSMLTIKYATRKDAGEYTITATNPFGTKVEH 20464
Query: 887 LVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
+ T DVPGP G + S + ++W P E G + Y + E +R V
Sbjct: 20465 VKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE 20524
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNI 1004
+ + T L Y V+A+ G+G+ V + + PGPP +SN+
Sbjct: 20525 -DIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNV 20583
Query: 1005 GPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNP 1063
+ T+ + RP DG + I+ + VE + E + + + +V L
Sbjct: 20584 TKNTATVSWKRPVDDGGSEITGYHVERR-----EKKSLRWVRAIKTPVSDLRCKVTGLQE 20638
Query: 1064 FTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPE 1122
+ Y FR+ N G PPS+ S + A P P+N + ++ S L W +
Sbjct: 20639 GSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAW---GK 20695
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G E GY +++ + + + DL+ +Y ++ A N G
Sbjct: 20696 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 20755
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
G + V E V + A +++VR L ++ K
Sbjct: 20756 VG---EPAVIPDVEIVEREMAPDFELDAELRRTLVVRAG-----------LSIRIFVPIK 20801
Query: 1243 DSDTQPRFWLVEG-NSSRSAQLTGLGKYVL--------YEVQVLAFTRIGDGSPSHPPIL 1293
W + N A + + L Y+ T +
Sbjct: 20802 GRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 20861
Query: 1294 ERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVL 1353
R L D PGP + + ++ SV L W P G + I + T + +T
Sbjct: 20862 VRVL-DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTK 20920
Query: 1354 APSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRP-MVQQED 1412
Y TGL Y FR+ A+ G GE E TTE + PS P + D
Sbjct: 20921 CHKC-TYKVTGLSEGCEYFFRVMAENEYGIGEPTE----TTEPVKASEAPSPPDSLNIMD 20975
Query: 1413 VRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTS 1471
+ +V L+W +P DG S + Y I+ + S +W H +V +V L
Sbjct: 20976 ITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWT-HITTV--KGLECVVRNLTEGEE 21032
Query: 1472 YKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKIN 1531
Y F+V A N G S P + V+++ Q +
Sbjct: 21033 YTFQVMAVNSAGRS-------------------------APRESRPVIVKEQTMLPE--- 21064
Query: 1532 GILLGFRIRYRELLY----EGLR-GFTLRGINNPGATWAELTSMYSM-RNLSRPSLTQYE 1585
L R Y++L+ + ++ + G P TW + + + ++ +
Sbjct: 21065 ---LDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 21121
Query: 1586 LDNLNKHRRYE---IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDV 1642
+ N+N+ R + ++ N VGE +V PT + ++ +
Sbjct: 21122 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGP---IKFDEVSSDFVTF 21178
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
+W+PP D I Y + + E T+ + K LT Y V A
Sbjct: 21179 SWDPPENDG-GVPISNYVVEMRQTDSTTWVELATTVI--RTTYKATRLTTGLEYQFRVKA 21235
Query: 1703 FNAAGDGPRSTPT--QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRL 1759
N G GP T P P + + + +T S+ +SW P G + GY +
Sbjct: 21236 QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHV 21295
Query: 1760 VYEPCSPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVT 1817
+ + + VSK + V GN K L +G+ Y FR+ A+ +
Sbjct: 21296 ERKERNGILWQTVSKAL---VPGNI---FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSE 21349
Query: 1818 TGPGEGAPGPPGVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKD 1875
PPG P+ + + + + W+ + G IT Y++E R G W +K
Sbjct: 21350 PMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW---LKA 21406
Query: 1876 IPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG-FGTPSSPSQSV 1918
+ F++ L +Y+FRVIA N G PS PS ++
Sbjct: 21407 NFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAI 21450
Score = 193 bits (490), Expect = 2e-48
Identities = 343/1510 (22%), Positives = 596/1510 (39%), Gaps = 171/1510 (11%)
Query: 473 YTCLATNSRG-VDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVT 526
+ +A N +G D S + + A+ + +P SV G + ++ P+ T
Sbjct: 23201 FRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT 23260
Query: 527 IRYIWEKDGATLGTESHPRIR--LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
I W KDG L + + LD +L I +T D G Y V + G + S +
Sbjct: 23261 IT--WTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQYGITVANVVGQKTASIEI 23317
Query: 585 RVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLLAS 642
P P+ PV V +I L+W P + G + YI++ + W V+ A+
Sbjct: 23318 VTLDKPDPPKGPVK-FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 23376
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERV--SLPEEPPTAPPQNVIAS 700
V T++ V L YQFR+ A N G+ F+ +++ + P + P PP A+
Sbjct: 23377 V--ARTTLKVTKLKTGTEYQFRIFAENRYGQS-FALESDPIVAQYPYKEP-GPPGTPFAT 23432
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED---- 756
+ S++IQW P + + ++ ++ R + +I VN ++ D
Sbjct: 23433 AISKDSMVIQWHEPVNNGGSPVIGYHLERK---------ERNSILWTKVNKTIIHDTQFK 23483
Query: 757 ---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWN 813
L YE V A N G+G +SK +E + P PPG I W
Sbjct: 23484 AQNLEEGIEYEFRVYAENIVGVGK-ASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 23542
Query: 814 APSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVL 872
P + G + + E+ + + +F + I F VSGL + Y V+
Sbjct: 23543 KPV------YDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVI 23596
Query: 873 CFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRI 930
G P + + ++V P +S ++ V+ E + G +
Sbjct: 23597 AKNAAGAISKPSDSTGPITAKDEVELP--RISMDPKFRDTIVVNAGETFRLEADVHGKPL 23654
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI--SSGV 988
E+ R + + + E + T AL ++ A GQ + AS + S
Sbjct: 23655 PTIEWLRGDKEIEE---SARCEIKNTDFKALLI--VKDAIRIDGGQYILRASNVAGSKSF 23709
Query: 989 PPEL-----PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEW 1041
P + PGPP + ++ + +L + P DG + IS ++VE + W
Sbjct: 23710 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRET---SRLAW 23766
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPA 1101
++ ++E S++V L Y FR+ VN G P + + + P
Sbjct: 23767 TVV---ASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPK 23823
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
++ + ++ S+ + W + +G E +GY ++ + D G + R+ +
Sbjct: 23824 SLEVTNIAKDSMTVCWN---RPDSDGGSEIIGYIVE--KRDRSGIRWIKCNKRRITDLRL 23878
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLV 1218
+ L E EY +V A NA G G P TV + + V GP TN + TT +S+ +
Sbjct: 23879 RVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITL 23938
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
W + P D +LGY V + D + G +++ L ++ Y+++V A
Sbjct: 23939 AWGK-PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 23997
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH 1338
++G G + P + D + P + L E+R GI++ +
Sbjct: 23998 LNKVGLGEATSVPGTVKPEDKLEAPELD-LDSELR--------------KGIVVRAGGSA 24042
Query: 1339 RLNTTTANTATVEVL-APSARQYTATGLKPESVYLFRITAQT--RKGWGE---------A 1386
R++ T E+ + ++T + V +++ R G+
Sbjct: 24043 RIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG 24102
Query: 1387 AEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSG 1445
+++ VT + D P PP V++ VR S L WEP DG + V+ Y I RE S
Sbjct: 24103 SKSAFVTVKVLDTPGPPQNLAVKE--VRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--ST 24158
Query: 1446 RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAP 1505
R A + S + +SF V+ L Y FRV A N+ G E +++ A P P
Sbjct: 24159 RKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKA--AEPPSPP 24216
Query: 1506 TILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWA 1565
+++T + TS + W+ P D + +L G+ + E+ +G +++
Sbjct: 24217 GKVTLTDVSQTSASLMWEKPEHDGGSRVL-GYVV---EMQPKGTEKWSI----------- 24261
Query: 1566 ELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVP-- 1623
++ + + L+ + Y+ R+ YN G+ S P+ + V
Sbjct: 24262 ----------VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK---SDPRVLGVPVIAKDL 24308
Query: 1624 TAAPRNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA 1681
T P + + Q D+ E P + +I K + + T RV A
Sbjct: 24309 TIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVK----DGEPLKQTTRVNVEETA 24364
Query: 1682 ENSV---KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
++V K N + Y +V A N+AG + + P P V+F E++
Sbjct: 24365 TSTVLHIKEGNKDDFGKY--TVTATNSAGTATENLSVIVLEKPGPPVGP--VRFDEVSAD 24420
Query: 1739 SVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTY 1797
V +SWE P + G + Y + E +V+ V + +K+ L G Y
Sbjct: 24421 FVVISWEPPAYTGGCQISNY--IVEKRDTTTTTWHMVSATVARTT---IKITKLKTGTEY 24475
Query: 1798 RFRIRAKTFTYGP----EIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGK 1851
+FRI A+ YG + +A + P + PGPPG P + S + + W + G
Sbjct: 24476 QFRIFAEN-RYGKSAPLDSKAVIVQYPFK-EPGPPGTPFVTSISKDQMLVQWHEPVNDGG 24533
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
I Y +E + + LW L K ++ T +D G+ Y+F+V A N G G P
Sbjct: 24534 TKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD---EGLEYEFKVSAENIVGIGKP 24590
Query: 1912 SSPSQSVPAQ 1921
S S+ A+
Sbjct: 24591 SKVSECFVAR 24600
Score = 192 bits (489), Expect = 2e-48
Identities = 323/1397 (23%), Positives = 511/1397 (36%), Gaps = 198/1397 (14%)
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
R + L I + D GTYT + G+ R+ H+ V P P + T ++
Sbjct: 15455 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVT--DIKAE 15512
Query: 607 AINLTWTKPFD-GNSPLIRYILEM---SENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662
+ LTW P D G S + Y+++ S A W + + K + L+P Y+
Sbjct: 15513 SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK--LIPNGQYE 15570
Query: 663 FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722
FR+ AVN G K + V PP RT S+++ W PP ++ + I
Sbjct: 15571 FRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPI 15630
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED-------LIIWTNYEIEVAAYNSAGL 775
GY + G P + ++ A + + L+ L+ Y+ A N+AG+
Sbjct: 15631 -TGYWLEKREEGSP---YWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGI 15686
Query: 776 GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT---IRFTWNAPSPQFINGINQGYKLIAW 832
G S+ ++ + G P PPG T I W P+ + G + +
Sbjct: 15687 GP-PSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAK------DGGSPIKGY 15739
Query: 833 EPEQEEEVTMVTARPNFQDSIHVG---FVSGLKKFTEYFTSVLCFTTPGDGPRS--TPQL 887
E +EE T R N D + V LK+ +Y V G+ S T ++
Sbjct: 15740 IVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI 15799
Query: 888 VRTH-EDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYL 946
T ++ P + + L + P G T + SWE + + +
Sbjct: 15800 PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTP-KSSWEFDGKAKKAMKDGV 15858
Query: 947 PNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA------STISSGVP-PELPGPPTNL 999
++ + ++ + I + G+ ++A T + V ++PGPP +L
Sbjct: 15859 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 15918
Query: 1000 GISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS--M 1056
+S+I S L ++ P DG I +++E + +G+ W ++ PD S
Sbjct: 15919 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVN-----PDCGSTTF 15970
Query: 1057 EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQA--PPDMAPANVSLRTASETSLW 1114
VPDL Y FR+R N G PP + ++ PPD P + + ++ ++
Sbjct: 15971 VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPD-PPIKLKIGLITKNTVH 16029
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ----DRVERDYTIEDLEEWTE 1170
L W P + +G Y ++ D G Q D E +T+EDL E E
Sbjct: 16030 LSWKP---PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGE 16086
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
Y +V+A NA G S TV GP + S L + EV E
Sbjct: 16087 YEFRVKAVNAAGVSKPSATV-----------GPCDCQRPDMPPSIDLKEFMEVEEGTNVN 16135
Query: 1231 LV-----------LGYKVMYKEKDS------DTQPRFWLVEGNSSRSAQLTGLGKYVLYE 1273
+V +K K+ D+ DT +V+ + + LY
Sbjct: 16136 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLY- 16194
Query: 1274 VQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIIL 1332
+ A +G S + + PGPP+G I F V + L W PP G +
Sbjct: 16195 -TITAVNNLGTASKE----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKI 16249
Query: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
+ + V P YT L Y+FRI AQ + G GE ++
Sbjct: 16250 TNYVIEKREANRKTWVHVS-SEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPE 16308
Query: 1393 TTEKR-DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALH 1450
T P P +P V V S+ ++W EP DG SPV Y ++ ++ S RW
Sbjct: 16309 TARNLFSVPGAPDKPTV--SSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRV 16366
Query: 1451 SASVSHNAS---SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
+ + S+ V L + Y+FRV A N G S S+ T P
Sbjct: 16367 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPF 16426
Query: 1508 LSVTPHTTTSVLIRWQPPAED---KINGILLGFR--------------IRYRELLYEGL- 1549
VT T +S + W PP +D K+ G ++ ++ +R +L+ GL
Sbjct: 16427 PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLK 16486
Query: 1550 ---------RGFTLRGINNPGATWAELTSMYSMRN-LSRP--SLTQYELDNLNKHRRYEI 1597
R + GI PG E+T + M++ L P L D + H I
Sbjct: 16487 EGAFYKFRVRAVNIAGIGEPG----EVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVI 16542
Query: 1598 RMSVYNAVGEGPS--------SPPQEVFV------------------------------G 1619
R+ Y + P+ + PQE + G
Sbjct: 16543 RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 16602
Query: 1620 EA----------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG 1669
E VP + H T +TW P D I Y I E+ R
Sbjct: 16603 ERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPE-DDGGSPITNYVIEKRESDRR 16661
Query: 1670 NLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQG---QTQQAAPSA 1726
T T + + ++ L AY +AA N+ G GP ++ + P
Sbjct: 16662 AWTP--VTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 16719
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P ++ E+T +V ++W P++ G E V E S + G K V
Sbjct: 16720 PEDLEVKEVTKNTVTLTWNPPKYDGG-SEIINYVLE--SRLIGTEKFHKVTNDNLLSRKY 16776
Query: 1787 KVKDLAEGVTYRFRIRA 1803
VK L EG TY +R+ A
Sbjct: 16777 TVKGLKEGDTYEYRVSA 16793
Score = 190 bits (483), Expect = 1e-47
Identities = 365/1536 (23%), Positives = 598/1536 (38%), Gaps = 180/1536 (11%)
Query: 448 QLPRFTPLESGSLLISPTHISDAGT-------YTCLATNSRGV--DEASADLVVWARTRI 498
+LP +++ I TH G + +A N+ GV + + + + AR +
Sbjct: 22479 ELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEV 22538
Query: 499 TKPP-------QDQSVIKGTQASMV-CGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LD 549
P +D V+ ++ V + P TI+ W K L + I+ D
Sbjct: 22539 DPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQ--WIKGDQELSNTARLEIKSTD 22596
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAIN 609
SL + D G Y + + G S + +++V P PE PV +S V
Sbjct: 22597 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVV-ISGVTAEKCT 22655
Query: 610 LTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCA 667
L W P DG S +I YI+E E + WTV+ A+V + VT L+ Y FR+ A
Sbjct: 22656 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTK--LLEGNEYTFRIMA 22713
Query: 668 VNDVGKGQFSKDTERVSL-PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGY 726
VN G G+ + V+ P P AP + + T S+++ W+ P + IL GY
Sbjct: 22714 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV-TKDSMIVVWERPASDGGSEIL-GY 22771
Query: 727 IIRYCLAGLPVGYQFKNITDADVNNLLLE--DLIIWTNYEIEVAAYNSAGLGVYS--SKV 782
++ G ++ + L L LI +YE V+A N+AGL S S
Sbjct: 22772 VLE---KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAY 22828
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN-QGYKLIAWEPEQEEEVT 841
+ PP N +++ +W+ P + G QGY ++ E T
Sbjct: 22829 QKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI--YDGGCEIQGY-IVEKCDVSVGEWT 22885
Query: 842 MVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPV--- 898
M T P + ++ L+K EY + G G H DVPGP+
Sbjct: 22886 MCTP-PTGINKTNIEVEKLLEKH-EYNFRICAINKAGVGE---------HADVPGPIIVE 22934
Query: 899 GHLSFSEI-LDTSLK--VSWQEPGEKNGI--LTGYRISWEEYNRTNTRVTHY-LPNVTLE 952
L +I LD L+ ++ + G + G ++ + + + + +VT
Sbjct: 22935 EKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 22994
Query: 953 YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQ 1012
+ L + Y +T + ++ ++ V + P PP NL ++ I SV++
Sbjct: 22995 FTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL-DTPSPPVNLKVTEITKDSVSIT 23053
Query: 1013 FRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRM 1071
+ P DG + I ++VE + E ++N S ++ L Y FR+
Sbjct: 23054 WEPPLLDGGSKIKNYIVEKR-----EATRKSYAAVVTN-CHKNSWKIDQLQEGCSYYFRV 23107
Query: 1072 RQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPES 1131
N G P+Q + I+ + P P +++ + S+ L W + E++G +
Sbjct: 23108 TAENEYGIGLPAQTADPIKVAEVP--QPPGKITVDDVTRNSVSLSWT---KPEHDGGSKI 23162
Query: 1132 VGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTV 1190
+ Y ++ H + S + + I +L + EY +V A N G S P S V
Sbjct: 23163 IQYIVEMQAK--HSEKWSECARVK-SLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAV 23219
Query: 1191 VGRTRESV--PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQP 1248
++ V P P S + + EVP + R + + D P
Sbjct: 23220 PIVAKDLVIEPDVKPAFSSYSVQVGQDLKI---EVPISGRPKPTITWT-------KDGLP 23269
Query: 1249 RFWLVEGNSSRSAQLTGL----------GKYVLYEVQVLAFTRIGDGSPSHPPILERTLD 1298
N + S LT L G+Y + V +G + S +E
Sbjct: 23270 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV-----VGQKTAS----IEIVTL 23320
Query: 1299 DVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA 1357
D P PP G + F +V S+ L W PP G + I + +TTT T V A A
Sbjct: 23321 DKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTT--TVWDVVSATVA 23378
Query: 1358 R-QYTATGLKPESVYLFRITAQTRKGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
R T LK + Y FRI A+ R G A E+ +V P PP P +
Sbjct: 23379 RTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATA--ISK 23436
Query: 1416 RSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S+++ W EP ++G SPV Y ++ +E S W + ++ H+ + F L+ Y+F
Sbjct: 23437 DSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHD-TQFKAQNLEEGIEYEF 23495
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV A N +G + S+ SE P P + V + T ++W P D +
Sbjct: 23496 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEIT---LQWTKPVYDG-GSM 23551
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
+ G+ + R+L P W + S N+ TQ+ + L + +
Sbjct: 23552 ITGYIVEKRDL---------------PDGRWMKA----SFTNVIE---TQFTVSGLTEDQ 23589
Query: 1594 RYEIRMSVYNAVG--------EGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT---QLDV 1642
RYE R+ NA G GP + EV + R+ +V A T + DV
Sbjct: 23590 RYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADV 23649
Query: 1643 TWEP-PPLDSQNGDIQGYKIYFWEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSV 1700
+P P ++ GD + E+ R + K L + ++++++ +
Sbjct: 23650 HGKPLPTIEWLRGDKE-----IEESARCEIKNTDFKALLIVKDAIRI------DGGQYIL 23698
Query: 1701 AAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLV 1760
A N AG +S P + V+ + +T+ +++W +P +G + V
Sbjct: 23699 RASNVAGS--KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPLQDGGSDISHYV 23755
Query: 1761 YEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIE-ANVTT 1818
E +V +V NS LKV L EG Y FRI A + G +E A V
Sbjct: 23756 VEKRETSRLAWTVVASEVVTNS---LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLM 23812
Query: 1819 GPGEGAPGPP-GVPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDI 1876
PGPP + + ++ + W+ D G I Y++E R W IK
Sbjct: 23813 KNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW---IKCN 23869
Query: 1877 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ ++ + L Y+FRV A N G G PS
Sbjct: 23870 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 23905
Score = 190 bits (482), Expect = 1e-47
Identities = 360/1569 (22%), Positives = 576/1569 (36%), Gaps = 242/1569 (15%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G + L +G P P ITW K + IL P +S ++ I + SD G
Sbjct: 13701 TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS-TVTIVDSKRSDTG 13759
Query: 472 TYTCLATNSRGVDEASADLVVWAR---------TRITK--------PPQDQSVIKGTQAS 514
TY A N G A ++ V + T +T PP+D S
Sbjct: 13760 TYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDG------GS 13813
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA 574
+ + R T +W K +T+ + +L N Y RV +
Sbjct: 13814 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKE-------------YIFRVAAE 13860
Query: 575 ---GGNDSRSAHLRVRQLPHAPEHPVATL--STVERRAINLTWTKPFD-GNSPLIRYILE 628
G + A + P P L S + + A+ LTW +P D G SP+ Y +E
Sbjct: 13861 NMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE 13920
Query: 629 MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--P 686
+ + V + K T+ VKGL + Y+FR+ A N G G+ SK TE + + P
Sbjct: 13921 RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP 13980
Query: 687 EEPPTAPPQNVIAS-GRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
+PP P + + G+T S+ + W P H G ++ Y+I G +
Sbjct: 13981 IDPPWPPGKPTVKDVGKT--SVRLNWTKP--EHDGGAKIESYVIEMLKTGTDEWVRVAE- 14035
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEA 802
LL L+ Y V A N AG S S + P PP +
Sbjct: 14036 -GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 14094
Query: 803 TNSTTIRFTWNAPSPQFINGI------NQGYKLIAWEP-EQEEEVTMVTARPNFQDSIHV 855
T W P + I + + W+ + + T T P + S++V
Sbjct: 14095 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYV 14154
Query: 856 GFVS-----GLKKFTEYFTSVLC---FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
V+ G +TE SVL FTT PGP L+ ++
Sbjct: 14155 FRVAAENAIGQSDYTEIEDSVLAKDTFTT------------------PGPPYALAVVDVT 14196
Query: 908 DTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTI 966
+ + W+ P G + Y I +E T +RVT + T
Sbjct: 14197 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 14256
Query: 967 EVAAMTSKGQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSI 1023
+V A G G S T +S P P PP +L +++ G + + + ++ P +G + I
Sbjct: 14257 QVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 14316
Query: 1024 SRWLVE-AQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
+ VE VG E+W+ ++ + D + + P Y R+R VN +G S P
Sbjct: 14317 IGYHVEMCPVGT----EKWMRVNSRPIK-DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 14371
Query: 1083 SQPSRKIQTLQAPPDMAPANVSLRTAS---------ETSLWLRWMPLPEMEYNGNPESVG 1133
S+ S + + PD P + L T + R +P+P + ++ + + V
Sbjct: 14372 SEISENV--VAKDPDCKP-TIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK 14428
Query: 1134 YKIKYSRSDGHGKTLSHV-VQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVG 1192
+ + + H +H+ V V D I Y + ++ N +GS S V
Sbjct: 14429 ASDRLTMKNDH--ISAHLEVPKSVRADAGI--------YTITLE--NKLGSATASINV-- 14474
Query: 1193 RTRESVPSSGP-TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW 1251
+ + GP ++ A T SS + W E PE D +L Y + + +++ +
Sbjct: 14475 ---KVIGLPGPCKDIKASDITKSSCKLTW-EPPEFDGGTPILHY--VLERREAGRRTYIP 14528
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILF 1309
++ G + S + L Y +V A ++G G P++ + P PP+ +
Sbjct: 14529 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 14588
Query: 1310 PEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPE 1368
++ + W+PP G I+ Y I E L P YTA GL+
Sbjct: 14589 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEG 14647
Query: 1369 SVYLFRITAQTRKGWGEAAEALVVT--TEKRDRPQPPSRPM--VQQEDVRARSVLLS--- 1421
Y FR+ A+ G E + A T + D P+ R V++ D A +S
Sbjct: 14648 KEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSP 14707
Query: 1422 -----WEPGSDGLSPV------------RYYTIQTRE---LPSGRWALHSASVSHNASSF 1461
W + + P R +Q E LP + S +
Sbjct: 14708 YPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLR 14767
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH-TTTSVLI 1520
+ D L+P + +K ND G +++ T+ P I V TSVL
Sbjct: 14768 VRDSLRPDHGL-YMIKVENDHG------IAKAPCTVSVLDTPGPPINFVFEDIRKTSVLC 14820
Query: 1521 RWQPPAEDKINGILLGFRIRYRELLYEGLRGFTL--RGINNPGATWAELTSMYSMRNLSR 1578
+W+PP +D + I+ +TL + P + W +TS ++R+
Sbjct: 14821 KWEPPLDDGGSEII----------------NYTLEKKDKTKPDSEWIVVTS--TLRH--- 14859
Query: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV-PTAAPRNVVVHGATA 1637
+Y + L + + Y R+ N G GP + + + P AP +V T+
Sbjct: 14860 ---CKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS 14916
Query: 1638 TQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQRGNLT--ERVKTLFLAENSVKLKNLTGYT 1694
+ V W P NG I G Y+ E + N T RV L + L
Sbjct: 14917 NSMLVKWNEP---KDNGSPILG---YWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 14970
Query: 1695 AYMVSVAAFNAAGDGPRSTPTQGQT--QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
Y+ V A NAAG G S P+ +T +P P + ++ ++T++ + WE P F G
Sbjct: 14971 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGG 15030
Query: 1753 ILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEI 1812
G + Y + G ++ K VK++ EG Y+ R+ A
Sbjct: 15031 ---GEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSA--------- 15078
Query: 1813 EANVTTGPGEGAPG------------PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860
GEG PG PP V + V I I GK V+
Sbjct: 15079 ----VNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIM-----AGKTLRIPAVVT 15129
Query: 1861 ARPSDEGLW 1869
RP +W
Sbjct: 15130 GRPVPTKVW 15138
Score = 189 bits (481), Expect = 2e-47
Identities = 331/1484 (22%), Positives = 562/1484 (37%), Gaps = 198/1484 (13%)
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTY 473
G S+ L G P P + W K G ++ + S SL++ + D+G Y
Sbjct: 22957 GGSLRLFVPIKGRPTPEVKWGK-----VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKY 23011
Query: 474 TCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTI------ 527
T NS G A + V PP + V + T+ S+ +T +P +
Sbjct: 23012 TLTLENSSGTKSAFVTVRV---LDTPSPPVNLKVTEITKDSV--SITWEPPLLDGGSKIK 23066
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAH 583
YI EK AT + + +N S I Q G +Y RV + G +++A
Sbjct: 23067 NYIVEKREATRKSYAAVVTNCHKN-SWKIDQLQEGC--SYYFRVTAENEYGIGLPAQTAD 23123
Query: 584 -LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
++V ++P P T+ V R +++L+WTKP DG S +I+YI+EM ++ A
Sbjct: 23124 PIKVAEVPQPPGK--ITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 23181
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ--------FSKDTERVSLPEEPPTAP 693
V K+ + L Y FR+ AVN+ G+ +KD V P+ P
Sbjct: 23182 RV--KSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL--VIEPDVKPAFS 23237
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK-NITDADVNNL 752
+V + I +P P I + GLP+ + N+TD+ L
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPT-----------ITWTKDGLPLKQTTRINVTDS----L 23282
Query: 753 LLEDLIIWTNYEIEVAAYNSAGLGVYSSKVT--EWTLQGVPTVPPGNVHAEATNSTTIRF 810
L L I ++ + Y V K E P P G V + ++ +I
Sbjct: 23283 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITL 23342
Query: 811 TWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTS 870
+WN P G ++ + ++ + T V + + V+ LK TEY
Sbjct: 23343 SWNPPL------YTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFR 23396
Query: 871 VLCFTTPGDG--PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTG 927
+ G S P + + PGP G + I S+ + W EP G + G
Sbjct: 23397 IFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 23456
Query: 928 YRISWEEYN-----RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAS 982
Y + +E N + N + H +++ L Y V A G G+ S +
Sbjct: 23457 YHLERKERNSILWTKVNKTIIH-----DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 23511
Query: 983 T--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGE 1039
+ + P + PG P + + +TLQ+ +P YDG + I+ ++VE + G
Sbjct: 23512 SECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWM 23568
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
+ + + + V L Y FR+ N G S+PS + A ++
Sbjct: 23569 KASFTNVIETQ-----FTVSGLTEDQRYEFRVIAKNAAGAI--SKPSDSTGPITAKDEVE 23621
Query: 1100 PANVSLR---------TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKT 1147
+S+ A ET + PLP +E+ + + + + K
Sbjct: 23622 LPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKA 23681
Query: 1148 LSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVS 1207
L +V+D + D + ++A N GS + V R P GP V+
Sbjct: 23682 LL-IVKDAIRIDGG----------QYILRASNVAGSKSFPVNVKVLDRPG-PPEGPVQVT 23729
Query: 1208 ALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS--SRSAQLTG 1265
+ TS + WS P G + + V+ K +T W V + + S ++T
Sbjct: 23730 GV--TSEKCSLTWS--PPLQDGGSDISHYVVEKR---ETSRLAWTVVASEVVTNSLKVTK 23782
Query: 1266 LGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
L + Y +++A + G G P P+L + +PGPP + + S+ + W P
Sbjct: 23783 LLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRP 23842
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
+ G + I + + + + + TGL + Y FR++A+ G G
Sbjct: 23843 DSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 23902
Query: 1385 EAAEALVV--TTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRE 1441
E + A V + +P PP+ + D S+ L+W +P DG S + Y ++ +
Sbjct: 23903 EPSPATVYYKACDPVFKPGPPTNAHIV--DTTKNSITLAWGKPIYDGGSEILGYVVEICK 23960
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
W + + + F + +L YK RV A N +G E + S T
Sbjct: 23961 ADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTVKPEDK 24018
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
EAP L + +++R A I +G P
Sbjct: 24019 LEAPE-LDLDSELRKGIVVRAGGSARIHI----------------------PFKGRPTPE 24055
Query: 1562 ATWAELTSMYS--MRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
TW+ ++ ++ + TQ +DN +++ + + + N+ G S V V
Sbjct: 24056 ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG----SKSAFVTVK 24111
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR---GNLTERVK 1676
P+N+ V + WEPP +D ++ Y I E+ R N++ +
Sbjct: 24112 VLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDG-GAKVKNYVIDKRESTRKAYANVSSK-- 24168
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELT 1736
++ S K++NLT Y V A N G G PS P V ++++
Sbjct: 24169 ---CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 24225
Query: 1737 TTSVNVSWEAPQFPNGI-LEGYRLVYEPCS----PVDGVSKIVTVDVKGNSPLWLKVKDL 1791
TS ++ WE P+ G + GY + +P + SK+ V G L
Sbjct: 24226 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTG----------L 24275
Query: 1792 AEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
+ G Y+FR++A Y + G+ P GVP+I +
Sbjct: 24276 SSGQEYQFRVKA----YNEK---------GKSDPRVLGVPVIAK 24306
Score = 189 bits (479), Expect = 3e-47
Identities = 429/1885 (22%), Positives = 716/1885 (37%), Gaps = 273/1885 (14%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAGR 180
V GE I P + P P V+W +DG+++ S R+ + ++ L + +V DAG
Sbjct: 14398 VIEGEKLSIPVP-FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGI 14456
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN 240
Y + N K G S I + V + GP I K + + + ++T E
Sbjct: 14457 YTITLEN-KLGSATAS--INVKVIGLPGPCKDI--------KASDITKSSCKLTWEPPEF 14505
Query: 241 ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVL-------RSSSV 293
LH + ++ + RR IP +G + + + ++ R +V
Sbjct: 14506 DGGTPILHYVLER---------REAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 14556
Query: 294 PSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW----YKDAAVV 349
V G Y+ L+ P ++P++ + VD+ +ITW Y + +
Sbjct: 14557 NKVGGGEYIE-LKNPVIAQDPKQ----PPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 14611
Query: 350 E---VEKLTRFRQR----NDGGLQI-----SGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
+EK+ + +R N+ + I GL F+ A NAAG + S
Sbjct: 14612 MGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPP 14671
Query: 398 TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLES 457
T I D V+L R ++ ++G+ I S+ S
Sbjct: 14672 TKAVDPI----------DAPKVIL--------RTSLEVKRGDEIALDASI---------S 14704
Query: 458 GSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVC 517
GS + T I D + + +A LV + + + ++ V+ TQ
Sbjct: 14705 GSPYPTITWIKDENVIV-----PEEIKKRAAPLVRRRKGEVQE--EEPFVLPLTQ----- 14752
Query: 518 GVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGN 577
R++I D + G ES R+R + D G Y +V + G
Sbjct: 14753 ------RLSI------DNSKKG-ESQLRVR----------DSLRPDHGLYMIKVENDHGI 14789
Query: 578 DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP- 635
+ V P P + V + + ++ W P D G S +I Y LE + P
Sbjct: 14790 AKAPCTVSVLDTPGPPINFV--FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPD 14847
Query: 636 --WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL-PEEPPTA 692
W V+ +++ SVT L+ + Y FR+ A N G G V+ P PP A
Sbjct: 14848 SEWIVVTSTLRHCKYSVTK--LIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 14905
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNL 752
P + ++ +N S++++W P + NG I+ Y L V + + + N
Sbjct: 14906 PDKPIVEDVTSN-SMLVKWNEPKD---NG---SPILGYWLEKREVNSTHWSRVNKSLLNA 14958
Query: 753 L---LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV--HAEATNSTT 807
L ++ L+ Y V A N+AG G +S T P PPG T+STT
Sbjct: 14959 LKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTT 15017
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTAR-PNFQDSIHVGFVSGLKKFTE 866
I W P+ N G +++ + +++ T +R + V +++ +
Sbjct: 15018 IELEWEPPA------FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGAD 15071
Query: 867 YFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKN---- 922
Y V G+GP Q V E P L D S+K Q K
Sbjct: 15072 YKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVEL------DVSVKGGIQIMAGKTLRIP 15125
Query: 923 GILTGYRIS---W--EEYNRTNTRVTHYLPNVTLEYRVTGLTALTT-YTIEVAAMTSKGQ 976
++TG + W EE RV + NV + + AL + V T+
Sbjct: 15126 AVVTGRPVPTKVWTKEEGELDKDRVV--IDNVGTKSELIIKDALRKDHGRYVITATNSCG 15183
Query: 977 GQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVV 1035
+ +A+ + ++PGP +L + L + P DG + I+ +++E + +
Sbjct: 15184 SKFAAARVEVF---DVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 15240
Query: 1036 GEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP 1095
+ + E + ++ L Y FR+ N G PP + +
Sbjct: 15241 HTWRQPI-------ETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLG 15293
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
P +P ++ +++++ L W E NG GY I+ R H K V R
Sbjct: 15294 PPTSPERLTYTERTKSTITLDWK---EPRSNGGSPIQGYIIEKRR---HDKPDFERVNKR 15347
Query: 1156 V--ERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGPTNVSALATT 1212
+ + +E+L+E Y +V+A N IG S P V + VP PT L+
Sbjct: 15348 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP---PTIKLRLSVR 15404
Query: 1213 SSSMLVRWSE---VPEADRNGLVLGYKVMYKEKDSDTQPR--FWLVEGNSSRSAQLTGLG 1267
++ V+ E +P AD GL + K + +P + + SRS T L
Sbjct: 15405 GDTIKVKAGEPVHIP-ADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 15463
Query: 1268 --KYVLYE---VQVLAFTRIGDGSPS-HPPILERTLDDVPGPPMGILFPEVRTTSVRLIW 1321
K V + V A R+G + H + +R P PP + +++ S L W
Sbjct: 15464 IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDR-----PSPPRNLAVTDIKAESCYLTW 15518
Query: 1322 QPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA-RQYTATGLKPESVYLFRITAQTR 1380
P G + + + + + + EV + ++Y L P Y FR+ A +
Sbjct: 15519 DAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNK 15578
Query: 1381 KGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQ 1438
G + ++ VV + P PP +P V S+L+SW P D G SP+ Y ++
Sbjct: 15579 YGISDECKSDKVVIQDPYRLPGPPGKPKVLART--KGSMLVSWTPPLDNGGSPITGYWLE 15636
Query: 1439 TRELPSGRWALHSAS----VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE-S 1493
RE S W+ S + V F V RL Y+FR A N G SE S+
Sbjct: 15637 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPE 15696
Query: 1494 LTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT 1553
+ P P+ V T +S+ + W+PPA+D + I G+ + +E EG +
Sbjct: 15697 VAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIK-GYIVEMQE---EGTTDW- 15751
Query: 1554 LRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSP 1612
+ +N P + + NL + R+Y R+ N GE PS
Sbjct: 15752 -KRVNEPDKLITTCECV---------------VPNLKELRKYRFRVKAVNEAGESEPSDT 15795
Query: 1613 PQEVFVGEA-------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
E+ + + A +V + ++ + P + + G +
Sbjct: 15796 TGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMK 15855
Query: 1666 AQRGNLTERVKTLFLAENSVKL------KNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQT 1719
++ E + L AENS + ++ TG S+ A N AG + T
Sbjct: 15856 DGVHDIPEDAQ-LETAENSSVIIIPECKRSHTG----KYSITAKNKAG---QKTANCRVK 15907
Query: 1720 QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDV 1778
P P +K S++T S +SW+ P G ++GY + +DG +
Sbjct: 15908 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT---IDGKAWTKVNPD 15964
Query: 1779 KGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEA-NVTTGPGEGAPGPPGVPIIVRY 1836
G++ V DL Y FR+RA+ F GP +E TT P P + + +
Sbjct: 15965 CGSTTF--VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 16022
Query: 1837 SSAIAIHWSSGDP---GKGPITRYVIEARPSD-----EGLWDILIKDIPKEVSSYTFSMD 1888
+ +H S P G P+T Y++E D + W K ++V F+++
Sbjct: 16023 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK---RDVEELQFTVE 16079
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSS 1913
L G Y+FRV AVN G PS+
Sbjct: 16080 DLVEGGEYEFRVKAVNAAGVSKPSA 16104
Score = 187 bits (474), Expect = 1e-46
Identities = 315/1447 (21%), Positives = 553/1447 (38%), Gaps = 151/1447 (10%)
Query: 524 RVTIRYIWEKDGATLGTESHPRIRLDRNGSL-HISQTWSGDIGTYTCRVISAGGNDSRSA 582
R T W KD L + N SL I D+G Y ++ ++ G +
Sbjct: 22174 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL 22233
Query: 583 HLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLL 640
++ V P P PV + V +I L+W P +DG S + YI+E + + W ++
Sbjct: 22234 NVIVLDKPGPPTGPVK-MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 22292
Query: 641 ASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIAS 700
A+V T++ L YQFR+ A N GK + V+ PP + +
Sbjct: 22293 ATV--ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 22350
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIW 760
+ S+ +QW P + ++ ++ R + + N T L
Sbjct: 22351 LSSRDSMEVQWNEPISDGGSRVIGYHLERK--ERNSILWVKLNKTPIPQTKFKTTGLEEG 22408
Query: 761 TNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFI 820
YE V+A N G+G SKV+E + P PPG A ++ W P+
Sbjct: 22409 VEYEFRVSAENIVGIGK-PSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPT---- 22463
Query: 821 NGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG- 878
+ G K+ + E++E + +F + I F V+GL + Y V+ G
Sbjct: 22464 --YDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 22521
Query: 879 -DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNR 937
P + + ++V P +S ++ V E + + + G I ++ +
Sbjct: 22522 FSEPSESTGAITARDEVDPP--RISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK 22579
Query: 938 TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL----- 992
+ +++ T + T+ +++ A G + A ++ +
Sbjct: 22580 GDQELSN-----TARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 22634
Query: 993 --PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP + IS + TL ++P DG + I ++VE + L+ +
Sbjct: 22635 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRE------TSRLVWTVVD 22688
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTA 1108
S +V L Y+FR+ VN G P + + AP + T
Sbjct: 22689 ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV 22748
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLE 1166
++ S+ + W +G E +GY ++ +G T H R+ E + L
Sbjct: 22749 TKDSMIVVW---ERPASDGGSEILGYVLEKRDKEGIRWTRCH---KRLIGELRLRVTGLI 22802
Query: 1167 EWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLVRWSEVP 1224
E +Y +V A NA G S P + + + + GP N + T SS+ + WS+ P
Sbjct: 22803 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK-P 22861
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV----EGNSSRSAQLTGLGKYVLYEVQVLAFT 1280
D + GY V + D W + G + + ++ L + Y ++ A
Sbjct: 22862 IYDGGCEIQGYIV----EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 22917
Query: 1281 RIGDGSPSHPP---ILERTLDDVPGPPMGILFPEVRTT----SVRLIWQPPAAPNGIILA 1333
+ G G + P I+E L+ P + + ++ S+RL P +
Sbjct: 22918 KAGVGEHADVPGPIIVEEKLE-APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 22976
Query: 1334 YQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY---LFRITAQTRKGWGEAAEAL 1390
++ + + A ++V + +T+ L + Y + +T + G ++
Sbjct: 22977 GKVDGEIR----DAAIIDVTS----SFTSLVLDNVNRYDSGKYTLTLENSSG----TKSA 23024
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
VT D P PP V + + SV ++WEP DG S ++ Y ++ RE +A
Sbjct: 23025 FVTVRVLDTPSPPVNLKVTE--ITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 23082
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
+ N S+ +D+L+ SY FRV A N+ G ++ ++ + + + P ++
Sbjct: 23083 VVTNCHKN--SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVP--QPPGKIT 23138
Query: 1510 VTPHTTTSVLIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE 1566
V T SV + W P D KI ++ + ++ E W+E
Sbjct: 23139 VDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-------------------KWSE 23179
Query: 1567 LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-------PSSPPQEVFVG 1619
+ S+ Q + NL + Y R+ N G P V
Sbjct: 23180 CARVKSL---------QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 23230
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF 1679
+ P + +V V ++ ++ P P + D K + R N+T+ +L
Sbjct: 23231 DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK----QTTRINVTD---SLD 23283
Query: 1680 LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTS 1739
L S+K + Y ++VA N G S + P P VKF +++ S
Sbjct: 23284 LTTLSIKETHKDDGGQYGITVA--NVVGQKTASIEIVTLDKPDPPKGP--VKFDDVSAES 23339
Query: 1740 VNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1799
+ +SW P + G + + + V +V+ V + LKV L G Y+F
Sbjct: 23340 ITLSWNPPLYTGGC-QITNYIVQKRDTTTTVWDVVSATVARTT---LKVTKLKTGTEYQF 23395
Query: 1800 RIRAKTF---TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGKGPI 1854
RI A+ ++ E + V P + PGPPG P S ++ I W + G P+
Sbjct: 23396 RIFAENRYGQSFALESDPIVAQYPYK-EPGPPGTPFATAISKDSMVIQWHEPVNNGGSPV 23454
Query: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSP 1914
Y +E + + LW + K I + F L+ G+ Y+FRV A N G G S
Sbjct: 23455 IGYHLERKERNSILWTKVNKTI---IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 23511
Query: 1915 SQSVPAQ 1921
S+ A+
Sbjct: 23512 SECYVAR 23518
Score = 177 bits (449), Expect = 1e-43
Identities = 352/1605 (21%), Positives = 600/1605 (37%), Gaps = 162/1605 (10%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP-------LDSTVI--DGM 417
+SGL D F+ A+NAAG + + + + P TVI G
Sbjct: 21418 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 21477
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ L + SG P P + W K + L G+ +L S +L+ + D+G YT A
Sbjct: 21478 AFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 21536
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP-------RVTIRYI 530
TN G + ++ V R PP+ + S C ++ P ++ +
Sbjct: 21537 TNPGGFAKHIFNVKVLDRPG---PPEGPLAVTEV-TSEKCVLSWFPPLDDGGAKIDHYIV 21592
Query: 531 WEKDGATLG-TESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA---GGNDSRSAHLRV 586
+++ + L T +++ + L +++ G+ Y RV++ G + + +
Sbjct: 21593 QKRETSRLAWTNVASEVQVTK---LKVTKLLKGN--EYIFRVMAVNKYGVGEPLESEPVL 21647
Query: 587 RQLPHAPEHPVAT--LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
P+ P P ++T+ + ++ + W P DG S +I YI+E + +
Sbjct: 21648 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 21707
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVG------KGQFSKDTERVSLPEEPPTAPPQNV 697
V GL Y+FR+ A N G F K + V P PP N
Sbjct: 21708 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKP-----GPPGNP 21762
Query: 698 IASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA---DVNNLLL 754
+ SI I W P + I GY++ L P +++ +T + +
Sbjct: 21763 RVLDTSRSSISIAWNKPIYDGGSEIT-GYMVEIAL---PEEDEWQIVTPPAGLKATSYTI 21818
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
L Y+I + A NS GLG + T + + P + +A +
Sbjct: 21819 TGLTENQEYKIRIYAMNSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACC 21876
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT--EYFTSVL 872
F+ + + W + E + + ++ + V + +F +Y +V
Sbjct: 21877 TLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI--VGNVNRFDSGKYILTV- 21933
Query: 873 CFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS 931
G +S VR D PGP L E+ TS+ ++W P G + Y +
Sbjct: 21934 ---ENSSGSKSAFVNVRVL-DTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE 21989
Query: 932 WEEYNR-------TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
E R TN T ++V L +Y V A G G + A T
Sbjct: 21990 KRESTRKAYSTVATNCHKT--------SWKVDQLQEGCSYYFRVLAENEYGIG-LPAETA 22040
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
S E P PP + + ++ SV+L + +P +DG + I ++VE Q ++W
Sbjct: 22041 ESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQ---TKGSDKWAT 22097
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPA 1101
+ + L YSFR+ N G S P Q S + + L PP
Sbjct: 22098 CATVK----VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLL 22153
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD-- 1159
+ + L + ++ + G P + + + + K + V + E +
Sbjct: 22154 FNTFTVLAGEDLKV------DVPFIGRPTPA---VTWHKDNVPLKQTTRVNAESTENNSL 22204
Query: 1160 YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR 1219
TI+D V+ N+ G + V+ + P +GP + + T+ S+ +
Sbjct: 22205 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG-PPTGPVKMDEV--TADSITLS 22261
Query: 1220 WSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYVLYEVQVLA 1278
W P+ D + Y V EK + + +V +R+ + L Y+ ++ A
Sbjct: 22262 WGP-PKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAA 22317
Query: 1279 FTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQ 1335
R G + S P + + VPGPP + S+ + W P + G ++ Y
Sbjct: 22318 ENRYGKSTYLNSEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYH 22376
Query: 1336 ITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTE 1395
+ + + + P + + TGL+ Y FR++A+ G G+ ++
Sbjct: 22377 LERKERNSILWVKLNKTPIPQTK-FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYV- 22434
Query: 1396 KRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASV 1454
RD PP RP + V SV L W +P DG S + Y ++ +ELP GRW + ++
Sbjct: 22435 ARDPCDPPGRP--EAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRW-MKASFT 22491
Query: 1455 SHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHT 1514
+ + F V L Y+FRV A N G FSE SES + A + P +S+ P
Sbjct: 22492 NIIDTHFEVTGLVEDHRYEFRVIARNAAG--VFSEPSESTGAITARDEVDPPRISMDPKY 22549
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-FTLRGINNPGATWAELTSMYSM 1573
++++ K++ + G I + ++G L + + S+
Sbjct: 22550 KDTIVV--HAGESFKVDADIYGKPIP----TIQWIKGDQELSNTARLEIKSTDFATSLSV 22603
Query: 1574 RNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVH 1633
++ R Y L N + ++V GP P VV+
Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGP----------------VVIS 22647
Query: 1634 GATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGY 1693
G TA + + W+ PPL DI Y + E R L V + S K+ L
Sbjct: 22648 GVTAEKCTLAWK-PPLQDGGSDIINYIVERRETSR--LVWTVVDANVQTLSCKVTKLLEG 22704
Query: 1694 TAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPN 1751
Y + A N G G S P + P AP + + + +T S+ V WE P
Sbjct: 22705 NEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDG 22764
Query: 1752 GI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT--- 1807
G + GY L + + + L L+V L E Y FR+ A+
Sbjct: 22765 GSEILGYVLEKRDKEGI----RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLS 22820
Query: 1808 -YGPEIEANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPS 1864
P P PGPP P ++ + S++ + WS G I Y++E
Sbjct: 22821 EPSPPSAYQKACDP-IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 22879
Query: 1865 DEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G W + P ++ ++ L Y+FR+ A+N G G
Sbjct: 22880 SVGEWTMCTP--PTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 22922
Score = 177 bits (449), Expect = 1e-43
Identities = 292/1333 (21%), Positives = 502/1333 (37%), Gaps = 167/1333 (12%)
Query: 647 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGR-TNQ 705
+T++ K S + L A N G F+K V + + P PP+ +A T++
Sbjct: 21516 STNLVNKDSTRRDSGAYTLTATNP---GGFAKHIFNVKVLDRP--GPPEGPLAVTEVTSE 21570
Query: 706 SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNNLLLEDLIIWTNYE 764
++ W PP + + YI++ + N+ ++ V L + L+ Y
Sbjct: 21571 KCVLSWFPPLDDG-GAKIDHYIVQKRETSR---LAWTNVASEVQVTKLKVTKLLKGNEYI 21626
Query: 765 IEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFING 822
V A N G+G + S V G P PP N ++ W P
Sbjct: 21627 FRVMAVNKYGVGEPLESEPVLAVNPYGPPD-PPKNPEVTTITKDSMVVCWGHPDS----- 21680
Query: 823 INQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-DG 880
+ G ++I + E+ ++ + N + + + VSGL + EY ++ G
Sbjct: 21681 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 21739
Query: 881 PRSTPQLVRTHEDV--PGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR 937
P T + + V PGP G+ + +S+ ++W +P G +TGY +
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 21799
Query: 938 TNTRVTHYLPNVTLE---YRVTGLTALTTYTIEVAAMTSKGQGQVSA-----STISSGVP 989
++ P L+ Y +TGLT Y I + AM S+G G+ + +P
Sbjct: 21800 DEWQIV--TPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 21857
Query: 990 PELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
PE+ + I F P +W + GE + I S+
Sbjct: 21858 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH-----GESLDKASIESTSS 21912
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
+ V ++N F + + N G+ R + T P D+ ++ +
Sbjct: 21913 YT---LLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDL-----KVKEVT 21964
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
+TS+ L W P P ++ G + Y ++ + + K S V + + + ++ L+E
Sbjct: 21965 KTSVTLTWDP-PLLD--GGSKIKNYIVE--KRESTRKAYSTVATNCHKTSWKVDQLQEGC 22019
Query: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSG----PTNVSALATTSSSMLVRWSEVPE 1225
Y +V A N G G + T ESV +S P ++ + T +S+ + W E PE
Sbjct: 22020 SYYFRVLAENEYGIG-----LPAETAESVKASERPLPPGKITLMDVTRNSVSLSW-EKPE 22073
Query: 1226 ADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDG 1285
D +LGY V + K SD V+ A +TGL + Y +V A G
Sbjct: 22074 HDGGSRILGYIVEMQTKGSDKWATCATVKVTE---ATITGLIQGEEYSFRVSAQNEKGIS 22130
Query: 1286 SPSH------------PP---ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
P PP +L T + G + + P + + + W P
Sbjct: 22131 DPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVP--- 22187
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ T R+N + ++ + + R+ Y+ ++T GEA E L
Sbjct: 22188 ---LKQTTRVNAESTENNSLLTIKDACREDVGH-------YVVKLTNSA----GEAIETL 22233
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
V D+P PP+ P V+ ++V A S+ LSW P DG S + Y ++ R+ + W +
Sbjct: 22234 NVIV--LDKPGPPTGP-VKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQI 22290
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
SA+V+ ++ RLK Y+FR+ A N G S + ++ P
Sbjct: 22291 VSATVAR--TTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV 22348
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + S+ ++W P D + ++ G+ L W +L
Sbjct: 22349 VTLSSRDSMEVQWNEPISDGGSRVI----------------GYHLERKERNSILWVKL-- 22390
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE--AVPTAAP 1627
N + T+++ L + YE R+S N VG G S E +V P P
Sbjct: 22391 -----NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRP 22445
Query: 1628 RNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKL 1687
++V T + + W+ P D I GY + E G + T + + ++
Sbjct: 22446 EAIIV---TRNSVTLQWKKPTYDG-GSKITGYIVEKKELPEGRWMKASFTNII-DTHFEV 22500
Query: 1688 KNLTGYTAYMVSVAAFNAAGDGPRSTPTQG----QTQQAAPSAPSSVKFSELTTTSVNVS 1743
L Y V A NAAG + + G + + P K+ + S
Sbjct: 22501 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 22560
Query: 1744 WEAPQFPNGILEGYRLVYEPCSPVDGV------SKIVTVDVKGNS-PLWLKVKDLAEGVT 1796
++ G +P + + S +++K L VKD +
Sbjct: 22561 FKVDADIYG---------KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 22611
Query: 1797 YRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGKGP 1853
+ ++AK + NV PGPP P+++ +A + W G
Sbjct: 22612 GNYILKAKNVAGERSVTVNVKV---LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSD 22668
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSS 1913
I Y++E R + +W + + V + + + L G Y FR++AVN YG G
Sbjct: 22669 IINYIVERRETSRLVWTV----VDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG---E 22721
Query: 1914 PSQSVPAQKANPF 1926
P +S P NPF
Sbjct: 22722 PLESEPVVAKNPF 22734
Score = 171 bits (433), Expect = 7e-42
Identities = 352/1639 (21%), Positives = 604/1639 (36%), Gaps = 203/1639 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL--------DSTVIDGM 417
+++ L D F+ FARNAA V + I + P D V+
Sbjct: 25745 EVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAG 25804
Query: 418 SVV-LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ + + +G P P I+W K + I + + L + D G Y
Sbjct: 25805 EVLKINADIAGRPLPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 25863
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
N G + + V + PP I G A C ++ W +
Sbjct: 25864 LKNVAGTRSVAVNCKVLDKPG---PPAGPLEINGLTAEK-CSLS----------WGRPQE 25909
Query: 537 TLGTESHPRIRLDRNGSLHISQT-WSGDIGTYTCRVIS-----------------AGGND 578
G + I +++ + H++ T G++ +C+V G
Sbjct: 25910 DGGADIDYYI-VEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 25968
Query: 579 SRSAHLRVRQLPHAPEHPVAT-LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPW 636
S ++ P P + +++V + ++ L W++P DG S + YI+E E N+
Sbjct: 25969 LESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLR 26028
Query: 637 TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT------ERVSLPEEPP 690
V + V GL Y++R+ A N G S+ + + V LP PP
Sbjct: 26029 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPS-PP 26087
Query: 691 TAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
+ P ++ SG+T +I I W P + GY + Y K D D
Sbjct: 26088 SKP--KIVDSGKT--TITIAWVKPLFDG-GAPITGYTVEY-----------KKSDDTDWK 26131
Query: 751 NLL---------LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAE 801
+ + L Y V + N G S + P ++ +E
Sbjct: 26132 TSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 26191
Query: 802 ATNSTTIR----FTWNAPS-----PQFI-NGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851
+ ++ FT P P + + + + A+ + ++ N D
Sbjct: 26192 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRND 26251
Query: 852 SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
S K+T +VL ++ LV D PGP +++ ++ S
Sbjct: 26252 S---------GKYTLTIQNVLS--------AASLTLVVKVLDTPGPPTNITVQDVTKESA 26294
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTN-TRVTHYLPNVTLEYRVTGLTALTTYTIEVA 969
+SW P G + Y I E ++ VT+ L Y+VT L Y V+
Sbjct: 26295 VLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNR--LSYKVTNLQEGAIYYFRVS 26352
Query: 970 AMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLV 1028
G G + A T E P PP LG+++I SV+L + +P +DG + I ++V
Sbjct: 26353 GENEFGVG-IPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVV 26411
Query: 1029 EAQVGVVGEGEE-WLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSR 1087
EA + +G++ W+ + V L + Y FR+ N G S P +
Sbjct: 26412 EA----LEKGQKNWVKCAVAKSTHHV----VSGLRENSEYFFRVFAENQAGLSDPRE--- 26460
Query: 1088 KIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY--NGNPESVGYKIKYSRSDGHG 1145
+ + + P + ++ ++++R +++ +G P K+ SR
Sbjct: 26461 LLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLP---KVTLSRDGVPL 26517
Query: 1146 KTLSHVVQDRVERDYTIEDLEEWTEY--RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP 1203
K + + TI E T R ++ A N+ G+ +V R P +GP
Sbjct: 26518 KATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG-PPTGP 26576
Query: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 1263
+S + T S+ ++W E P+ D V Y ++ +E + +
Sbjct: 26577 VVISDI--TEESVTLKW-EPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 26633
Query: 1264 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD-DVPGPPMGILFPEVRTTSVRLIWQ 1322
G+ Y+ ++ A R G + L PGPP V S+ + W
Sbjct: 26634 LTTGEE--YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWH 26691
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
P + G + + + L + T + +Y FR+ A+ G
Sbjct: 26692 EPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAG 26751
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRE 1441
G+ + D +PP V+ D+ SV LSW+ P DG S + Y ++ R+
Sbjct: 26752 VGKPSHPSEPVLAI-DACEPPRN--VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRD 26808
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
LP GRW S + + + FI+ L + Y+FRV A N +G S SE + +
Sbjct: 26809 LPDGRWTKASFT-NVTETQFIISGLTQNSQYEFRVFARNAVGS--ISNPSEVVGPITCID 26865
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
++ + P T V ++YR LR + G P
Sbjct: 26866 SYGGPVIDL-PLEYTEV--------------------VKYRAGTSVKLRA-GISGKPAPT 26903
Query: 1562 ATW------AELTSMYSMRNLSR-PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ 1614
W + ++ + N + S+ + D LN YE+++ NA+G ++
Sbjct: 26904 IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-YELKLR--NAMGSASATIRV 26960
Query: 1615 EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTER 1674
++ + + P P + TA ++ + W PP D G KI + ++ +
Sbjct: 26961 QI-LDKPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITHYIVEKRETSRV 27011
Query: 1675 VKTLF---LAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSS 1729
V ++ L E + + Y+ V A N G G S + P P
Sbjct: 27012 VWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 27071
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ +++T S+ V W P G + GY L + G K++ ++ KV
Sbjct: 27072 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIRDTRQ---KV 27127
Query: 1789 KDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGPPGVPIIVRYS----SAIAIH 1843
L E Y++R+ A GP E + + PPG P +R + S+I +
Sbjct: 27128 TGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID-PPGPPAKIRIADSTKSSITLG 27186
Query: 1844 WSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
WS G +T YV+E R +E W + EV + + + LKPGV+Y FRV A
Sbjct: 27187 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTV--STKGEVRTTEYVVSNLKPGVNYYFRVSA 27244
Query: 1903 VNDYGFGTPSSPSQSVPAQ 1921
VN G G P ++ V A+
Sbjct: 27245 VNCAGQGEPIEMNEPVQAK 27263
Score = 167 bits (423), Expect = 1e-40
Identities = 305/1309 (23%), Positives = 495/1309 (37%), Gaps = 158/1309 (12%)
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+++ + P PE T ++ + +++LTW KP DG S ++ Y++E E V A
Sbjct: 26369 VKITEKPSPPEKLGVT--SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAV 26426
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPE--EPPTAPPQN---- 696
K+T V GL Y FR+ A N G + V + E EPP +N
Sbjct: 26427 A--KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 26484
Query: 697 ---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLL 753
V A I I +P P+ + G+P+ + T+ NL
Sbjct: 26485 TVYVRAGSNLKVDIPISGKPLPK-----------VTLSRDGVPLKATMRFNTEITAENLT 26533
Query: 754 --LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
L++ + E+ A NS+G + G PT P V ++
Sbjct: 26534 INLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP---VVISDITEESVTLK 26590
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEE----EVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W P +G +Q I + E EV+ AR + V L EY
Sbjct: 26591 WEPPK---YDGGSQVTNYILLKRETSTAVWTEVSATVARTMMK-------VMKLTTGEEY 26640
Query: 868 FTSVLCFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
+ G D S V+ PGP + + S+ V W EP G
Sbjct: 26641 QFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSA 26700
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
+ GY + ++ N + + L T ++VT ++A Y V A + G G+ S +
Sbjct: 26701 VVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPS- 26759
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ + PP N+ I++I SV+L ++ P +DG + I+ ++VE + G +
Sbjct: 26760 EPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTK--- 26816
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQ---PSRKIQTLQAPPDMA 1099
+N + + + + L + Y FR+ N VG+ S PS+ P I + P
Sbjct: 26817 -ASFTNVTETQFI-ISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 26874
Query: 1100 PANVS--LRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE 1157
P + ++ + TS+ LR +G P I++ + D +T + V +
Sbjct: 26875 PLEYTEVVKYRAGTSVKLR------AGISGKPAPT---IEWYKDDKELQTNALVCVENTT 26925
Query: 1158 --RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTV-VGRTRESVPSSGPTNVSALATTSS 1214
I+D + +++ NA+GS S T+ V + P GP +
Sbjct: 26926 DLASILIKDADRLNSGCYELKLRNAMGSA--SATIRVQILDKPGPPGGPIEFKTVTAEKI 26983
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTG--LGKYVLY 1272
++L R P AD G + + ++ K + S W + +T + K Y
Sbjct: 26984 TLLWR----PPADDGGAKITHYIVEKRETSRV---VWSMVSEHLEECIITTTKIIKGNEY 27036
Query: 1273 EVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI- 1330
+V A + G G P ++ + PGPP ++ S+ ++W P A G
Sbjct: 27037 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 27096
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA- 1389
I Y + R + ++ RQ TGL S Y +R+ A G G +E
Sbjct: 27097 ISGYFLEKRDKKSLGWFKVLKETIRDTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPS 27155
Query: 1390 -LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW 1447
+ D P PP++ ++ D S+ L W +P DG S V Y ++ R+ W
Sbjct: 27156 EFYKAADPIDPPGPPAK--IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEW 27213
Query: 1448 ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
S + ++V LKP +Y FRV A N G E E +E + EAP I
Sbjct: 27214 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL--EAPEI 27271
Query: 1508 LSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE- 1566
+ TSV+ + ED +L+ F +G P TW +
Sbjct: 27272 -DLDVALRTSVIAK---AGEDV--QVLIPF-----------------KGRPPPTVTWRKD 27308
Query: 1567 -----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEA 1621
+ YS+ N SL N +Y +++ N VGE P S V V +
Sbjct: 27309 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY--ILTIENGVGE-PKSSTVSVKVLD- 27364
Query: 1622 VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF-- 1679
P A + V H + T + + W+PP +D G I + ++ + T+R ++
Sbjct: 27365 TPAACQKLQVKHVSRGT-VTLLWDPPLIDG------GSPIINYVIEKRDATKRTWSVVSH 27417
Query: 1680 -LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ S KL +L+ T + V A N G G T+ P+ + + T T
Sbjct: 27418 KCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKT 27477
Query: 1739 SVNVSWEAPQFPNGILEGYRLVY-----EPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAE 1793
SV +SW P F G + +V E G+SK ++ V L E
Sbjct: 27478 SVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIE----------VSQLKE 27527
Query: 1794 GVTYRFRIRAKT-------FTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
FR+ AK T GP + P PG + VR
Sbjct: 27528 QSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR 27576
Score = 164 bits (414), Expect = 1e-39
Identities = 332/1511 (21%), Positives = 556/1511 (36%), Gaps = 169/1511 (11%)
Query: 473 YTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRY--- 529
+ A N +G+ + + + I P D S I G Q ++ G H+ + + Y
Sbjct: 27533 FRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIG--HNVHLELPYKGK 27590
Query: 530 -----IWEKDGATLGTESHPRIRLDRNG-SLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
W KDG L R N +L I G YT + +A +
Sbjct: 27591 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPIT 27650
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP-WTVLLA 641
+ P P+ P+ ++ ++ L+W P D G + Y +E E + W ++ +
Sbjct: 27651 VITLGPPSKPKGPIR-FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 27709
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
SV T+ V LV YQFR+ A N G Q + V+ + PP +
Sbjct: 27710 SV--ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYN 27767
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T+ + + W P + + ++ + + +Q N + L+
Sbjct: 27768 VTSDGMSLTWDAPVYDGGSEVTGFHVEKK--ERNSILWQKVNTSPISGREYRATGLVEGL 27825
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
+Y+ V A NSAGL S +++TL P PPG TI WN P
Sbjct: 27826 DYQFRVYAENSAGLSSPSDP-SKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLR---- 27880
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-- 878
+ G K++ + E+ + R NF D + V+GL Y ++ G
Sbjct: 27881 --DGGSKIVGYSIEKRQGNER-WVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI 27937
Query: 879 DGPRSTPQLVRTHEDVPGPV---GHLSFSEIL---DTSLKVSWQEPGEKNGILTGYRISW 932
P + ++ T ++ P+ G F ++ SL++ G +T ++
Sbjct: 27938 SPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGV 27997
Query: 933 EEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R N +T L + +L R YT+E A + G + P ++
Sbjct: 27998 EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE--AKNASGSAKAEIKVKVQDTPGKV 28055
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
GP + +NI +TL + P DG I+ +++E + W LI ++
Sbjct: 28056 VGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRET---SRLAWALIE---DKC 28106
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1111
+A+S L Y FR+ VN G P + +Q AP +
Sbjct: 28107 EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGN 28166
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLEEWT 1169
S+ L W E +G E Y ++ R + V+ R E + + L E
Sbjct: 28167 SITLTWA---RPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRFKVTGLTEGN 28221
Query: 1170 EYRVQVQAFNAIGSGPWSQ-TVVGRTRESV-PSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
EY V A NA G GP S + + + RE V P PT V T+ +++ + WS+ P D
Sbjct: 28222 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK-PVFD 28280
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++GY + + D + E +T L Y+ +V A G G
Sbjct: 28281 GGMEIIGYIIEMCKADLGDWHKV-NAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDS 28339
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ-------ITHRL 1340
+ +D + P + I +T VR A + +AYQ + +
Sbjct: 28340 CEVTGTIKAVDRLTAPELDIDANFKQTHVVRA-----GASIRLFIAYQGRPTPTAVWSKP 28394
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + A + S T + +T + G ++++ T + D P
Sbjct: 28395 DSNLSLRADIHT-TDSFSTLTVENCNRNDAGKYTLTVENNSG----SKSITFTVKVLDTP 28449
Query: 1401 QPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP + +DV S L W+ P DG + + +Y ++ RE W + S +
Sbjct: 28450 GPPGP--ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI- 28506
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT-TLQAAPDEAPTILSVTPHTTTSV 1518
F V+ L Y FRV A N+ G E E E + T Q AP P L V + +S
Sbjct: 28507 -FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP---PRRLDVVDTSKSSA 28562
Query: 1519 LIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
++ W P D +I G LL R + + E G T +LT
Sbjct: 28563 VLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHT-----------KQLT------- 28602
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------PTA---- 1625
+ ++ L + YE R+ N G S P+E F + PTA
Sbjct: 28603 --------FTVERLVEKTEYEFRVKAKNDAGY---SEPREAFSSVIIKEPQIEPTADLTG 28651
Query: 1626 -APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE-RVKTLFLAEN 1683
+ + + +DV P ++ ++ E R ++T + +T ++
Sbjct: 28652 ITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK--ETDRVSITTTKDRTTLTVKD 28709
Query: 1684 SVK---------LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSE 1734
S++ L+N G + V+V G P G + ++ SA S V
Sbjct: 28710 SMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG------PVTGPIEVSSVSAESCV---- 28759
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+SW P+ G E + E ++V VK +KV L +
Sbjct: 28760 -------LSWGEPKDGGGT-EITNYIVEKRESGTTAWQLVNSSVKRTQ---IKVTHLTKY 28808
Query: 1795 VTYRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPG 1850
+ Y FR+ ++ F +E A + P P P + S+ A++I W G
Sbjct: 28809 MEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDG 28868
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
I Y +E + + LW +K+ + + L G+ Y FR A+N G
Sbjct: 28869 GSKIIGYWVEKKERNTILW---VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 28925
Query: 1911 PSSPSQSVPAQ 1921
S S+ + AQ
Sbjct: 28926 ASEASRPIMAQ 28936
Score = 161 bits (408), Expect = 6e-39
Identities = 283/1169 (24%), Positives = 437/1169 (37%), Gaps = 141/1169 (12%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLI-SPTHISDA 470
T+ G S+ L SG P P ITW K LAS ++ ES SLLI + DA
Sbjct: 29457 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI----IDTTESYSLLIVDKVNRYDA 29512
Query: 471 GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV----- 525
G YT A N G A+ + V+ T P +K V P +
Sbjct: 29513 GKYTIEAENQSGKKSATVLVKVYD----TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAP 29568
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVI-----SAGGNDSR 580
YI EK A + + + IS G + Y RV+ G
Sbjct: 29569 VNNYIVEKREAAMRAFKTVTTKCSKT-LYRISGLVEGTM--YYFRVLPENIYGIGEPCET 29625
Query: 581 SAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP-FDGNSPLIRYILEMSENNAPWT 637
S + V ++P P A L V+ + + L W KP +DG S L Y+LE +
Sbjct: 29626 SDAVLVSEVPLVP----AKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW 29681
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS------LPEEPPT 691
+ + ++ P TV L Y FR+ A N+ G + + V+ LP +
Sbjct: 29682 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 29741
Query: 692 APPQNVI--ASGRTNQSIM-IQWQPPPESHQNGILKGYIIRYCLAG--LPVGYQFKNITD 746
PQ I +GR + ++ I +PPP + + AG L + T
Sbjct: 29742 TMPQKTIHVPAGRPVELVIPIAGRPPPAAS-----------WFFAGSKLRESERVTVETH 29790
Query: 747 ADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
V L + + I E + N G + KV G PT P + + ++T
Sbjct: 29791 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP---IKIDEIDAT 29847
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEE-------VTMVTARPNFQDSIHVGFVS 859
+I +W P ++ G L + EQ + V+ R F+ +
Sbjct: 29848 SITISWEPPE------LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFK-------FT 29894
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLV--RTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G G +++ R+ +PGP L ++ + ++W
Sbjct: 29895 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 29954
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +TGY + +E + +P YR TGLT Y V A+ ++G
Sbjct: 29955 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 30014
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVG 1033
G+ S + I + P PG P N +++ SV+L + P +G + ++ +L+E Q
Sbjct: 30015 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 30074
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQT 1091
+ EW + + R + L Y FR+ N G P++ + K+
Sbjct: 30075 ---DQHEWTKCNTTPTK--IREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 30129
Query: 1092 LQAPPDMA-----PANVSLRTASETSLWL--RWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
+ PD + +R L + + P P ++ + + + + S+ H
Sbjct: 30130 MLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH 30189
Query: 1145 GKTLSHVVQDRVERDYTIEDL--EEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSS- 1201
+ V+++ D DL E + IGS P+S
Sbjct: 30190 TEL---VIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS---------------PNSP 30231
Query: 1202 -GPTNVSALATTSSSMLVRWSEVPEADRNGL-VLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
GP + S VR S P AD G +LGY + +E W + R
Sbjct: 30232 EGPLEYDDIQVRS----VRVSWRPPADDGGADILGYILERREVPKAA----WYTIDSRVR 30283
Query: 1260 SAQLT--GLGKYVLYEVQVLAFTRIGDGSP--SHPPILERTLDDVPGPPMGILFPEV--- 1312
L GL + V Y +V A + G P S P+ +T + P PP PEV
Sbjct: 30284 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP--PEVLDV 30341
Query: 1313 RTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+SV L W P G + R T+T + YT TGL P++ Y
Sbjct: 30342 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 30401
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGL 1429
FRI AQ G E + A VV + D+P P ++ + SV L WE P DG
Sbjct: 30402 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE--LEILSISKDSVTLQWEKPECDGG 30459
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+ Y ++ R+ W S F + L T Y+FRV A N+ G S
Sbjct: 30460 KEILGYWVEYRQSGDSAWK-KSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 30518
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSV 1518
+ S+ T + EAP I TT +
Sbjct: 30519 TAMSIKT-KLTSGEAPGIRKEMKDVTTKL 30546
Score = 158 bits (400), Expect = 5e-38
Identities = 355/1546 (22%), Positives = 567/1546 (36%), Gaps = 189/1546 (12%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
G P P+I WYKD ++ L D + I ++G ++ RNA G +
Sbjct: 26898 GKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT 26957
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVL----ACETSGAPRPAITWQKGERILASGSVQ 448
+ + P GP++ + + L + GA +K E S+
Sbjct: 26958 IRVQILD-KPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMV 27016
Query: 449 LPRFTPLESGSLLISPTHISDAGTY--TCLATNSRGVDE-ASADLVVWARTRITK-PPQD 504
+I+ T I Y A N G+ E +D VV +T PP
Sbjct: 27017 SEHLE-----ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 27071
Query: 505 QSVIKGTQASMVCGVTH-----DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
V K T+ SM + ++ ++ ++D +LG + + T
Sbjct: 27072 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLT 27131
Query: 560 WSGDIGTYTCRVISAG-GNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
+ D C V +AG G S + P P P A + + + +I L W+KP
Sbjct: 27132 ENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPV 27191
Query: 616 FDGNSPLIRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S + Y++E+ + WT + + + T V L P +Y FR+ AVN G+G
Sbjct: 27192 YDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG 27251
Query: 675 QFSKDTERVSLPE--EPP-----TAPPQNVIASGRTNQSIMIQW--QPPPESHQNGILKG 725
+ + E V + E P A +VIA + ++I + +PPP K
Sbjct: 27252 EPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKN 27311
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
G Y +N D ++LL + + + + G+G S
Sbjct: 27312 -------LGSDARYSIEN---TDSSSLLTIPQVTRNDTGKYILTIEN-GVGEPKSSTVSV 27360
Query: 786 TLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTA 845
+ P + + + T+ W+ P I+ G +I + E+ + +
Sbjct: 27361 KVLDTPAACQ-KLQVKHVSRGTVTLLWDPPL------IDGGSPIINYVIEKRDATKRTWS 27413
Query: 846 RPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFS 904
+ + S + L + T +F VL G G P T + V+ E VP P+ LS
Sbjct: 27414 VVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE-VPAPIRDLSMK 27472
Query: 905 EILDTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTT 963
+ TS+ +SW +P G ++T Y + E + +H + T E V+ L +
Sbjct: 27473 DSTKTSVILSWTKPDFDGGSVITEYVV--ERKGKGEQTWSHAGISKTCEIEVSQLKEQSV 27530
Query: 964 YTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPG------Y 1017
V A KG TI EL P + +S+I VT++ Y
Sbjct: 27531 LEFRVFAKNEKGLS--DPVTIGPITVKELIITP-EVDLSDIPGAQVTVRIGHNVHLELPY 27587
Query: 1018 DGKTSIS-RW------LVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
GK S W L E++ + E + + + + + L+ C
Sbjct: 27588 KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRI-- 27645
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPE 1130
+ ++ PPS+P I+ + D S+ L W +P E NG E
Sbjct: 27646 AVPITVITLGPPSKPKGPIRFDEIKAD--------------SVILSW-DVP--EDNGGGE 27688
Query: 1131 SVGYKI-KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-S 1187
Y I K S + K + V + + +L + EY+ +V+A N G S P S
Sbjct: 27689 ITCYSIEKRETSQTNWKMVCSSV---ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 27745
Query: 1188 QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS--- 1244
+V + + +P P TS M + W + P D V G+ V KE++S
Sbjct: 27746 SIIVAKHQFRIPGP-PGKPVIYNVTSDGMSLTW-DAPVYDGGSEVTGFHVEKKERNSILW 27803
Query: 1245 ---DTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD--D 1299
+T P S R + TGL + + Y+ +V A G SPS P + D
Sbjct: 27804 QKVNTSP-------ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVD 27856
Query: 1300 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSA 1357
PG P I +V ++ L W PP G I+ Y I R N +V S
Sbjct: 27857 PPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDV---SE 27910
Query: 1358 RQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARS 1417
QYT TGL P Y FRI A+ G RD P P+V+
Sbjct: 27911 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVP---PIVEFGPEYFDG 27967
Query: 1418 VLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY----- 1472
+++ G S +Q R +P W + + I D L + +
Sbjct: 27968 LII-----KSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT 28022
Query: 1473 -----KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAE 1527
+ V+A N G S ++E +Q P + + T T + + W P
Sbjct: 28023 RDHRGVYTVEAKNASG----SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLN 28078
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
D I + I RE WA + S T +L
Sbjct: 28079 DGCAPI-THYIIEKRE---------------TSRLAWALIED-----KCEAQSYTAIKLI 28117
Query: 1588 NLNKHRRYEIRMSVYNAVGEGP--SSPPQEVFVGEAVPTA----APRNVVVHGATATQLD 1641
N N+ Y+ R+S N G G S P + VP A P N+ T +
Sbjct: 28118 NGNE---YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNI-----TGNSIT 28169
Query: 1642 VTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVA 1701
+TW P D +IQ Y + E + + + ++E K+ LT Y V
Sbjct: 28170 LTWARPESDG-GSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVM 28228
Query: 1702 AFNAAGDGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGY 1757
A NAAG GP S + + + P P+ VK ++ + T+V++ W P F G+ + GY
Sbjct: 28229 AENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGY 28288
Query: 1758 RLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA 1803
+ E C + V+ + V DL G Y+FR+ A
Sbjct: 28289 --IIEMCKA--DLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSA 28330
Score = 158 bits (399), Expect = 6e-38
Identities = 319/1434 (22%), Positives = 534/1434 (37%), Gaps = 160/1434 (11%)
Query: 531 WEKDGATLGTESHPRIRLD-RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W KD A + + I+ +L + D G Y V ++ G+ + V
Sbjct: 16852 WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 16911
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P PV+ V + + ++W P D G S + YI+E E + + S K T
Sbjct: 16912 PGPPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-T 16969
Query: 649 SVTVKGLVPARSYQFRLCAVNDVG-KGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
+ V L+ + Y FR+ A N G D+ + P AP Q ++ T S
Sbjct: 16970 TCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEV-TKDSA 17028
Query: 708 MIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNITDADVN---NLLLEDLIIWTNY 763
++ W P H G + YI+ + ++ +T ++ + DL+ Y
Sbjct: 17029 LVTWNKP---HDGGKPITNYILE---KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 17082
Query: 764 EIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
E V+A N G+G S SK PP N A T ++ TW P +
Sbjct: 17083 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 17142
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG- 880
I GY ++ ++ +EE P V+GL+ Y VL G+
Sbjct: 17143 KI-LGY-IVEYQKVGDEEWRRANHTPESCPETKYK-VTGLRDGQTYKFRVLAVNAAGESD 17199
Query: 881 PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGY---RISWEEYNR 937
P P+ V + + P L + + +KV + + I+ G +++W++ +R
Sbjct: 17200 PAHVPEPVLVKDRLEPPELILDANMAREQHIKVG--DTLRLSAIIKGVPFPKVTWKKEDR 17257
Query: 938 ---TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGV-PPELP 993
T R+ LE R Y++ V + + T+S V + P
Sbjct: 17258 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLVLDKP 17310
Query: 994 GPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
GPP +L +S I S L ++ P DG + I+ ++VE + +W LS
Sbjct: 17311 GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVA---SAQW---SPLSATSK 17364
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ-APPDMAPANVSLRTASET 1111
+S LN Y FR+ N G P + + I+ L P P ++ +T
Sbjct: 17365 KKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKT 17424
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG----KTLSHVVQDRVERDYTIEDLEE 1167
+ L W + + +G GY ++Y KT++++ + + L++
Sbjct: 17425 EVSLVW---NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNL-------ECVVTGLQQ 17474
Query: 1168 WTEYRVQVQAFNAIGSGPWSQTVVGRTRES-VPSSGPTNVSAL--------ATTSSSMLV 1218
YR +V+A N +G G T+ +E VP S +V + T ++
Sbjct: 17475 GKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAII 17534
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
R VP A K + T + + N S + + E Q+
Sbjct: 17535 RGVPVPTA---------KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI-- 17583
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQIT 1337
+ + + S + T+ DVPGPP G I +V + + WQPP G + I
Sbjct: 17584 --TVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIV 17641
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEK 1396
+ T +T V S + L+ Y+FR+ A+ + G G ++ V K
Sbjct: 17642 EK-QDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHK 17700
Query: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
P PP +P+V D+ + +SW P SDG SP+ Y ++ RE+ +G+W + +
Sbjct: 17701 FSPPSPPGKPVV--TDITENAATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPI 17757
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHT 1514
+ F V L +Y+FRV A N G S+ S S+ + + P I + +
Sbjct: 17758 ADL-KFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS 17816
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMR 1574
+ + W P D + IL G+ + A W + +R
Sbjct: 17817 RETADLVWTKPLSDGGSPIL----------------GYVVECQKPGTAQWNRINKDELIR 17860
Query: 1575 NLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVVV 1632
+ + + L + Y R+ N VGEG E + + + P +V
Sbjct: 17861 QCA------FRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTC 17914
Query: 1633 HGATATQLDVTW----------EPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
++ T EP ++ G + R + ++ L E
Sbjct: 17915 RDVITVRVGQTIRILARVKGRPEPDITWTKEGKV---------LVREKRVDLIQDLPRVE 17965
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
+K + Y++S A N++G S + P ++K + +T + +
Sbjct: 17966 LQIKEAVRADHGKYIIS--AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKENCTI 18020
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIR 1802
SWE P NG E + E P IV DV + +K LA Y FR+
Sbjct: 18021 SWENP-LDNGGSEITNFIVEYRKPNQKGWSIVASDV---TKRLIKANLLANN-EYYFRVC 18075
Query: 1803 AKT-FTYGPEIEA-------NVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD-PGKGP 1853
A+ GP IE N PGE P + I + + + + W D G P
Sbjct: 18076 AENKVGVGPTIETKTPILAINPIDRPGE----PENLHIADKGKTFVYLKWRRPDYDGGSP 18131
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG 1907
Y +E R W+ + K KE + +D Y+FRV N+ G
Sbjct: 18132 NLSYHVERRLKGSDDWERVHKGSIKETH---YMVDRCVENQIYEFRVQTKNEGG 18182
Score = 158 bits (399), Expect = 6e-38
Identities = 293/1278 (22%), Positives = 490/1278 (38%), Gaps = 155/1278 (12%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW-YKDAAVVEVEKLTRFRQR 360
L VL P++ I + V++ G PPP+ +W + + + E E++T
Sbjct: 29732 LRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 29791
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
L I DTG + +N G + T + P GP+ ID S+
Sbjct: 29792 KVAKLTIRETTIRDTGEYTLELKNVTG-TTSETIKVIILDKPGPPTGPIKIDEIDATSIT 29850
Query: 421 LACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISP---THISDAGTY 473
++ E GAP ++ P + P+ S S+ S T +++ Y
Sbjct: 29851 ISWEPPELDGGAPLSGY-------VVEQRDAHRPGWLPV-SESVTRSTFKFTRLTEGNEY 29902
Query: 474 T--CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
ATN G+ V+ R+ I P +++ + V+ D Y
Sbjct: 29903 VFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETL-------QIFDVSRDGMTLTWYPP 29955
Query: 532 EKDGATLGT---ESHPRIRLD---RNGSLHISQTWSGDIG-----TYTCRVIS----AGG 576
E DG + T +R D R + ++ T G Y RV + G
Sbjct: 29956 EDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 30015
Query: 577 NDSRSAHLRVRQLPHA----PEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSE 631
SR + V P A P++P T +T R +++L W+ P D G S + Y++EM +
Sbjct: 30016 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTT--RTSVSLAWSVPEDEGGSKVTGYLIEMQK 30073
Query: 632 NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS------KDTERVSL 685
+ + K T+ L Y+FR+ A N G G+ + K TE +
Sbjct: 30074 VDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEY 30133
Query: 686 PEEPPTAPPQN---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
P+ Q V G +I I+ +P P I ++ G + +
Sbjct: 30134 PDYELDERYQEGIFVRQGGVIRLTIPIKGKPFP-----------ICKWTKEGQDISKRAM 30182
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEA 802
T L++++ + ++ N G KV + G P P G + +
Sbjct: 30183 IATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKV---RVIGSPNSPEGPLEYDD 30239
Query: 803 TNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSG 860
++R +W P+ + G ++ + E+ E + T + + V V G
Sbjct: 30240 IQVRSVRVSWRPPAD------DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKG 30291
Query: 861 LKKFTEYFTSVLCFTTPG-DGPRSTPQLVRTHEDVPGPVGHLSFSEILD---TSLKVSWQ 916
LK+ EY V G P + + V + P + E+LD +S+ +SW
Sbjct: 30292 LKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 30351
Query: 917 EPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSK 974
P + G +TGY I +E T+ V H +T Y VTGL Y + A
Sbjct: 30352 RPKDDGGSRVTGYYIERKE-TSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDV 30410
Query: 975 GQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYD-GKTSISRWLVEA 1030
G + S ++ + P + P P L I +I SVTLQ+ +P D GK + W+
Sbjct: 30411 GLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYR 30470
Query: 1031 QVGVVGEGEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
Q G W + SN+ + + + L T Y FR+ N G S P + +
Sbjct: 30471 QSG----DSAW----KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 30522
Query: 1089 IQTL----QAP---PDMAPANVSLRTASETSLWLRWMPLPEME-YNGNPESVGYKIKYSR 1140
I+T +AP +M L A++ S + PLP+++ Y E + +
Sbjct: 30523 IKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 30582
Query: 1141 SDGHGKTLSHVVQDRVERDY-----TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRT 1194
SDG TL+ + +++ + T E E T ++ +QA G P + G
Sbjct: 30583 SDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG-- 30640
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKD---SDTQPRFW 1251
+V S+ +V + +M W G K++ ++ +T+
Sbjct: 30641 --AVGSTLRLHVMYIGRPVPAM--TWFH-----------GQKLLQNSENITIENTEHYTH 30685
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFP 1310
LV N R T GKY + V + IL+ + D P P G I+
Sbjct: 30686 LVMKNVQRK---THAGKYKVQLSNVFG---------TVDAILDVEIQDKPDKPTGPIVIE 30733
Query: 1311 EVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
+ S + W+PPA G + + + + A S L +
Sbjct: 30734 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 30793
Query: 1371 YLFRITAQTRKGWGEAAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSD 1427
Y FR++AQ G + E ++V+ ++P P +P + V S +++W+ P SD
Sbjct: 30794 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA--VTKDSCVVAWKPPASD 30851
Query: 1428 GLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEF 1487
G + +R Y ++ RE +W + + + F V L Y+FRVK N G+SE+
Sbjct: 30852 GGAKIRNYYLEKREKKQNKW-ISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 30910
Query: 1488 SEESESLTTLQAAPDEAP 1505
SE SE +T P +AP
Sbjct: 30911 SEISEPITPKSDVPIQAP 30928
Score = 155 bits (392), Expect = 4e-37
Identities = 154/607 (25%), Positives = 250/607 (41%), Gaps = 52/607 (8%)
Query: 24 VSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITS--- 80
V P F T ++ L G+ +V+ C GS P+ W H E++ +Y+ +T
Sbjct: 7680 VPPSF-TRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISS-GRKYQTTLTDNTC 7737
Query: 81 ------LDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRA 134
L+ + +G Y CI N G+ + + V SF + V G +
Sbjct: 7738 ALTVNMLEESDSGDYTCIATNMAGSD-ECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTS 7796
Query: 135 PRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNK 194
+ P V+WF+ ++ P R ++LE+++ L D + N K
Sbjct: 7797 I-VKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGK 7855
Query: 195 TSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKD 254
S L ++ AP + N + + LE P I + WKK+
Sbjct: 7856 ASCTTHLYIK---------APAKFVKRLNDYSIEKGKPLILEGTFTGTPPIS--VTWKKN 7904
Query: 255 GVLLSGG------ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP 308
G+ ++ ++ + L IP+ T DAG Y C + +S S A + +LEPP
Sbjct: 7905 GINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCY-IENASGKDSC--SAQILILEPP 7961
Query: 309 QFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQIS 368
FVK+ E + + + CQ G P ++WYK + + RN+ +
Sbjct: 7962 YFVKQLEP-VKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF 8020
Query: 369 GLVP-DDTGMFQCFARNAAGEVQTSTYLAVTS--IAPNITRGPLDSTVIDGMSVVLACET 425
V +D+G + C A N+ GEV ST+L V + P+ +R D G+ VV C
Sbjct: 8021 NQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAI 8080
Query: 426 SGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
SG+ +++W K G+ + S +VQ + +L I T S AG Y+C ATN G
Sbjct: 8081 SGSEPISVSWYKDGKPLKDSPNVQTSFLD--NTATLNIFKTDRSLAGQYSCTATNPIGSA 8138
Query: 485 EASADLVVWARTRITKPP------QDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL 538
+SA L++ T PP + G A C VT + + W KD +
Sbjct: 8139 SSSARLIL---TEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVS--WAKDSREI 8193
Query: 539 GTESHPRIR-LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
+ +I L+ + L + + GD G YTC ++ G DS +A L +++ P
Sbjct: 8194 RSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 8253
Query: 598 ATLSTVE 604
TVE
Sbjct: 8254 RLSETVE 8260
Score = 154 bits (390), Expect = 7e-37
Identities = 325/1603 (20%), Positives = 591/1603 (36%), Gaps = 176/1603 (10%)
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV-EVEKLTRFRQRNDGGLQISGLVPDDT 375
++ A + +D+P KG P ++ W KD + E ++ + L I +D
Sbjct: 25405 NVKAREQLKIDVPF--KGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDV 25462
Query: 376 GMFQCFARNAAGEVQTS-TYLAVTSIAPNITRGPLDSTVIDGMSVVLA---------CET 425
G ++ N+AG + T + + P GP+ + S+ ++ C+
Sbjct: 25463 GTYELCVSNSAGSITVPITIIVLDRPGPP---GPIRIDEVSCDSITISWNPPEYDGGCQI 25519
Query: 426 SG-----APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
S + TW + +A S+++ R T +GS + A N
Sbjct: 25520 SNYIVEKKETTSTTWHIVSQAVARTSIKIVRLT---TGSEY----------QFRVCAENR 25566
Query: 481 RGVDEASADLVVWARTRITKP--PQDQSVIKGTQASM--------------VCGVTHDPR 524
G S V A + P P V+ T+++M V G + +
Sbjct: 25567 YGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYK 25626
Query: 525 VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH- 583
+W K L ++ ++ G ++ + ++ +I G S+S
Sbjct: 25627 ERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGI--------GKCSKSCEP 25678
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+ R P P T + R++++L W+KP +DG + + YI+E E +
Sbjct: 25679 VPARDPCDPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 25736
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGK-GQFSKDTERVSLPEEPPTAPPQNVIASG 701
+ + T V L + Y+FR+ A N + S+ T + + ++ P V+
Sbjct: 25737 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDD---VEPPRVMMDV 25793
Query: 702 RTNQSIMIQWQPPPESHQNGILKGY---IIRYCLAGLPVGYQFKN-ITDADVNNLL-LED 756
+ I+++ + N + G +I + G+ + + + I D + LL ++D
Sbjct: 25794 KFRDVIVVKAGEVLKI--NADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 25851
Query: 757 LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
I + + N AG S + P P G + + +W P
Sbjct: 25852 CIRRDTGQYVLTLKNVAGT---RSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 25908
Query: 817 PQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTT 876
G + Y ++ E + + Q + V+ L K EY V
Sbjct: 25909 ED--GGADIDYYIV--EKRETSHLAWTICEGELQMTSCK--VTKLLKGNEYIFRVTGVNK 25962
Query: 877 PGDGPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G G ++ + VP P L + + S+ + W P G ++GY I
Sbjct: 25963 YGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERR 26022
Query: 934 EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST--ISSGVPPE 991
E N + P L + TGL Y V A + G S ++ I + P
Sbjct: 26023 EKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVF 26082
Query: 992 LPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 1050
LP PP+ I + G ++T+ + +P +DG I+ + VE + + +W Q
Sbjct: 26083 LPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKS---DDTDWKTSIQSLRG 26139
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS-------RKIQTL-QAPPDMAPAN 1102
+ + L Y FR++ VN VG S PS S R+ + L +M
Sbjct: 26140 TE---YTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTL 26196
Query: 1103 VSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTI 1162
+ AS T M +P + G P + +S+ D +T ++V TI
Sbjct: 26197 IVKAGASFT------MTVP---FRGRPVP---NVLWSKPDTDLRTRAYVDTTDSRTSLTI 26244
Query: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222
E+ + + N + + S T+V + ++ PTN++ T S ++ W +
Sbjct: 26245 ENANRNDSGKYTLTIQNVLSAA--SLTLVVKVLDT--PGPPTNITVQDVTKESAVLSW-D 26299
Query: 1223 VPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR-SAQLTGLGKYVLYEVQVLAFTR 1281
VPE D V Y + EK ++ + V N +R S ++T L + +Y +V
Sbjct: 26300 VPENDGGAPVKNYHI---EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENE 26356
Query: 1282 IGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLN 1341
G G P+ + + + P PP + + SV L W P G + + + L
Sbjct: 26357 FGVGIPAETKEGVK-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALE 26415
Query: 1342 TTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQ 1401
N V+ + + +GL+ S Y FR+ A+ + G + E L+ K ++ +
Sbjct: 26416 KGQKNW--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIK-EQLE 26472
Query: 1402 PPSRPMVQQED----VRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
PP M VRA S L P S P+ T+ +P + ++
Sbjct: 26473 PPEIDMKNFPSHTVYVRAGSNLKVDIPISG--KPLPKVTLSRDGVPLKATMRFNTEITAE 26530
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
+ + + ++ + A N G ++ L + P P ++S T S
Sbjct: 26531 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLD--RPGPPTGPVVISDI--TEES 26586
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLS 1577
V ++W+PP D + + + L A W E+++ + +
Sbjct: 26587 VTLKWEPPKYDGGSQVT----------------NYILLKRETSTAVWTEVSATVARTMMK 26630
Query: 1578 RPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVV-VHGAT 1636
LT E Y+ R+ N G V V T P + V T
Sbjct: 26631 VMKLTTGE--------EYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVT 26682
Query: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAY 1696
+ V W P + + + GY + + + L ++ L + K+ ++ Y
Sbjct: 26683 RESITVGWHEP-VSNGGSAVVGYHLEMKD-RNSILWQKANKLVIRTTHFKVTTISAGLIY 26740
Query: 1697 MVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LE 1755
V A NAAG G S P++ A P +V+ ++++ SV++SW+ P F G +
Sbjct: 26741 EFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKIT 26800
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPE 1811
GY + E DG + + + L + Y FR+ A+ + + E
Sbjct: 26801 GY--IVERRDLPDG--RWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 26856
Query: 1812 IEANVTTGPGEGAPG---PPGVPIIVRYSSAIAIHWSSGDPGK 1851
+ +T G P P +V+Y + ++ +G GK
Sbjct: 26857 VVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 26899
Score = 152 bits (385), Expect = 3e-36
Identities = 144/585 (24%), Positives = 243/585 (41%), Gaps = 44/585 (7%)
Query: 22 DDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYM---- 77
D + P T+ ++ ++G+ + L C+ GS P+ +W +++E++ S +Y++
Sbjct: 4670 DLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISA-SEKYKFSFHDN 4728
Query: 78 -----ITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVI 132
I+ L+ T +G Y C N+ G Q + V F E + Q V+ +
Sbjct: 4729 TAFLEISQLEGTDSGTYTCSATNKAGHN-QCSGHLTVKEPPYFVEKPQSQDVNPNTRVQL 4787
Query: 133 RAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAGRYYVQAVNDK 189
+A + P + WF+D +++ + ++ ++T L + + A D+G Y Q ND
Sbjct: 4788 KALVGGTAPMT-IKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDV 4846
Query: 190 NGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHI 249
+ TL V+ P I P V+ T EC P K+ +
Sbjct: 4847 G---TATSKATLFVKE--------PPQFIKKPSPVLVLRNGQSTTFECQITGTP--KIRV 4893
Query: 250 IWKKDG----VLLSGGIS--DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLS 303
W DG + GIS D I ++G Y CEA + + + L
Sbjct: 4894 SWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIE---LK 4950
Query: 304 VLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR-ND 362
V EPP F++E + + V++ C+ G PP +TW K+ + K R +
Sbjct: 4951 VKEPPTFIREL-KPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSV 5009
Query: 363 GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLA 422
L I+ P DTG +QC N G ST +A+ P+ + ++T + S
Sbjct: 5010 FNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE-PPSFIKKIENTTTVLKSSATFQ 5068
Query: 423 CETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRG 482
+G+P +ITW K ++IL F +L I +G YTC A N G
Sbjct: 5069 STVAGSPPISITWLKDDQILDEDDNVYISFVD-SVATLQIRSVDNGHSGRYTCQAKNESG 5127
Query: 483 VDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTES 542
V+ A L+V +I + + V + ++ C V P + ++ W KDG +
Sbjct: 5128 VERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVK--WLKDGKQIVPSR 5185
Query: 543 HPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
+ + + N S I D G YT +V + G+ S A+LRV
Sbjct: 5186 YFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 5230
Score = 149 bits (376), Expect = 3e-35
Identities = 359/1701 (21%), Positives = 599/1701 (35%), Gaps = 236/1701 (13%)
Query: 305 LEPPQFVKEPERH--ITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTR---FRQ 359
+EPP+ + + + I + +V+ I G P P I+W KD +E+E+ R
Sbjct: 25784 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDG--IEIEERARTEIIST 25841
Query: 360 RNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSV 419
N L + + DTG + +N AG + V P GPL+ +
Sbjct: 25842 DNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLD-KPGPPAGPLEINGLTAEKC 25900
Query: 420 VLAC----ETSGAPRPAITWQKGER-----ILASGSVQLP--RFTPLESGSLLISPTHIS 468
L+ E GA +K E + G +Q+ + T L G+ I
Sbjct: 25901 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI------ 25954
Query: 469 DAGTYTCLATNSRGVDEASADLVVWARTRIT--KPPQDQSVIKGTQASMVCGVTHDPRVT 526
+ N GV E + + A T PP + T+ SM
Sbjct: 25955 ----FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMT---------- 26000
Query: 527 IRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W + + G+E I ++R + Y RV S G + RV
Sbjct: 26001 --LCWSRPESDGGSEISGYI-IERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRV 26057
Query: 587 RQ-----------------------LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPL 622
LP P P S + I + W KP FDG +P+
Sbjct: 26058 YAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDS--GKTTITIAWVKPLFDGGAPI 26115
Query: 623 IRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTE 681
Y +E + ++ W + S+ + T T+ GL Y FR+ +VN VG S ++
Sbjct: 26116 TGYTVEYKKSDDTDWKTSIQSL--RGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 26173
Query: 682 RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILK---GYIIRYCLAGLPVG 738
PQ IA R + + + E + I+K + + G PV
Sbjct: 26174 ------------PQ--IAKEREEEPL---FDIDSEMRKTLIVKAGASFTMTVPFRGRPVP 26216
Query: 739 YQFKNITDADVNNLLLEDLI-IWTNYEIEVAAYNSAG------LGVYSSKVTEWTLQGVP 791
+ D D+ D T+ IE A N +G V S+ ++ +
Sbjct: 26217 NVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLD 26276
Query: 792 TV-PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 850
T PP N+ + + +W+ P N K E + + V+ N
Sbjct: 26277 TPGPPTNITVQDVTKESAVLSWDVPE----NDGGAPVKNYHIEKREASKKAWVSVTNNCN 26332
Query: 851 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDT 909
+ V+ L++ Y+ V G G P T + V+ E P P L + I
Sbjct: 26333 RLSYK--VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK-PSPPEKLGVTSISKD 26389
Query: 910 SLKVSWQEPGEKNGI-LTGYRISWEEYNRTN------TRVTHYLPNVTLEYRVTGLTALT 962
S+ ++W +P G + Y + E + N + TH++ V+GL +
Sbjct: 26390 SVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHV--------VSGLRENS 26441
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
Y V A G + + +L P + + N S T+ R G + K
Sbjct: 26442 EYFFRVFAENQAGLSDPRELLLPVLIKEQL--EPPEIDMKNF--PSHTVYVRAGSNLKVD 26497
Query: 1023 IS-RWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +V + +G + + E A ++ + T + R ++ +S
Sbjct: 26498 IPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY-EITAANSSG 26556
Query: 1082 PSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY-KIKYS 1139
++ I L P P P +S +E S+ L+W P +Y+G + Y +K
Sbjct: 26557 TTKAFINIVVLDRPGPPTGPVVIS--DITEESVTLKWEP---PKYDGGSQVTNYILLKRE 26611
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
S +S V + + + L EY+ +++A N G + +
Sbjct: 26612 TSTAVWTEVSATVARTMMK---VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYT 26668
Query: 1200 SSGPTNVSALA-TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN-- 1256
+ GP + + T S+ V W E P ++ V+GY + K+++S W
Sbjct: 26669 TPGPPSTPWVTNVTRESITVGWHE-PVSNGGSAVVGYHLEMKDRNS----ILWQKANKLV 26723
Query: 1257 -SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVR 1313
+ ++T + ++YE +V A G G PSHP P+L D PP + ++
Sbjct: 26724 IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVL---AIDACEPPRNVRITDIS 26780
Query: 1314 TTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
SV L WQ PA G + I R + + Q+ +GL S Y F
Sbjct: 26781 KNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEF 26840
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPP--SRPMVQQEDVRARS-VLLSWEPGSDGL- 1429
R+ A+ G +V D P P+ E V+ R+ + G G
Sbjct: 26841 RVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKP 26900
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+P + +EL + AL + + +S ++ S + +K N +G + +
Sbjct: 26901 APTIEWYKDDKELQTN--ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 26958
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGL 1549
+ L + P P + T + + W+PPA+D G +I +
Sbjct: 26959 RVQILD--KPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITH-------- 27000
Query: 1550 RGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP 1609
+ + W+ ++ +L +T + K Y R+ N G G
Sbjct: 27001 --YIVEKRETSRVVWSMVS-----EHLEECIIT---TTKIIKGNEYIFRVRAVNKYGIGE 27050
Query: 1610 SSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR 1668
V A T P + V T + V W P D DI G YF E +
Sbjct: 27051 PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADG-GSDISG---YFLEKRD 27106
Query: 1669 GNLTERVKTL--FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ---GQTQQAA 1723
K L + + K+ LT + Y V A NAAG GP S P++
Sbjct: 27107 KKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 27166
Query: 1724 PSAPSSVKFSELTTTSVNVSWEAPQFPNG-ILEGYRLVYEPCSPVDGVSKIVTVDVKGN- 1781
P P+ ++ ++ T +S+ + W P + G + GY + + TV KG
Sbjct: 27167 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE----EEWTTVSTKGEV 27222
Query: 1782 SPLWLKVKDLAEGVTYRFR------------------IRAKTFTYGPEIEANVTTGPGEG 1823
V +L GV Y FR ++AK PEI+ +V
Sbjct: 27223 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVI 27282
Query: 1824 APGPPGVPIIVRYSS--AIAIHWSSGDPGKGPITRYVIEARPS------------DEGLW 1869
A V +++ + + W + G RY IE S D G +
Sbjct: 27283 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 27342
Query: 1870 DILIKDIPKEVSSYTFSMDIL 1890
+ I++ E S T S+ +L
Sbjct: 27343 ILTIENGVGEPKSSTVSVKVL 27363
Score = 149 bits (376), Expect = 3e-35
Identities = 360/1644 (21%), Positives = 594/1644 (36%), Gaps = 223/1644 (13%)
Query: 367 ISGLVPDDTGMFQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMS 418
++ L + +F+ A+N G E T+ + + P I + I G
Sbjct: 29696 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 29755
Query: 419 VVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
V L +G P PA +W G ++ S V + T + L I T I D G YT
Sbjct: 29756 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV--AKLTIRETTIRDTGEYTLEL 29813
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASM------------VCGVTHDPRV 525
N G + +++ + P I T ++ + G + R
Sbjct: 29814 KNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRD 29873
Query: 526 TIRYIW--EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
R W + T T R+ ++ T IG+Y + + + RS+
Sbjct: 29874 AHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSI 29929
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
++P PE + V R + LTW P D G S + YI+E E A V +
Sbjct: 29930 ----RIPGPPE--TLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNK 29983
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER-VSLPEEPPTAPPQNVIASG 701
V T GL Y+ R+ A+N G G+ S+ ++ V++ P PQN +
Sbjct: 29984 VPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTD 30043
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T S+ + W P E + GY+I + N T + L L
Sbjct: 30044 TTRTSVSLAWSVP-EDEGGSKVTGYLIEMQKVDQHEWTKC-NTTPTKIREYTLTHLPQGA 30101
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
Y V A N+ G G P PG V + + + ++
Sbjct: 30102 EYRFRVLACNAGG-------------PGEPAEVPGTVKV----TEMLEYPDYELDERYQE 30144
Query: 822 GI--NQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
GI QG + P + + + QD ++ + TE V+ GD
Sbjct: 30145 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL---VIKEADRGD 30201
Query: 880 ------------GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
G ++ VR P G L + +I S++VSW+ P + G +
Sbjct: 30202 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 30261
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV--SASTI 984
GY + E + T V GL Y V+A G + S +
Sbjct: 30262 GYILERREVPKAAWYTIDSRVRGT-SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 30320
Query: 985 SSGVPPELPGPPTNLG-ISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWL 1042
+ P P PP+N + ++ SV+L + RP DG + ++ + +E + ++W
Sbjct: 30321 TPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETST---DKW- 30376
Query: 1043 LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG---TSPPSQPSRKIQTLQAPPDMA 1099
+ + V L P Y FR+ N VG TSP S+P P
Sbjct: 30377 -VRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQ-- 30433
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ER 1158
P + + + S+ S+ L+W + E +G E +GY ++Y +S S+ ++R+ ++
Sbjct: 30434 PGELEILSISKDSVTLQW---EKPECDGGKEILGYWVEYRQSGDSAWKKSN--KERIKDK 30488
Query: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP----------TNVSA 1208
+TI L E TEY +V A N G +T + + P T +
Sbjct: 30489 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGE 30548
Query: 1209 LATTSSSMLVRWSEVPEADRNGLVLGYKVMYK-EKDSDTQPRFWLVEGNSSRSAQLTGLG 1267
A S ++ R + R G L YK D T + E G
Sbjct: 30549 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDE-------G 30601
Query: 1268 KYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL----IWQP 1323
Y +A +G+ S +L+ T PG P+ + +++RL I +P
Sbjct: 30602 VYTC-----IATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRP 30656
Query: 1324 PAAPNGIILAYQITHRLNTTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A + + N T NT ++ + ++ T G +++ G
Sbjct: 30657 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK-------YKVQLSNVFG 30709
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYTIQTRE 1441
+A ++ E +D+P P+ P+V E + S ++SW+P DG S + Y ++ E
Sbjct: 30710 TVDA----ILDVEIQDKPDKPTGPIVI-EALLKNSAVISWKPPADDGGSWITNYVVEKCE 30764
Query: 1442 LPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
G W L S+++S + L Y FRV A N G S+ E S + +
Sbjct: 30765 AKEGAEWQLVSSAISVTTCRIV--NLTENAGYYFRVSAQNTFGISDPLEVSS--VVIIKS 30820
Query: 1501 PDE---APTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
P E AP ++T T S ++ W+PPA D G +IR + L
Sbjct: 30821 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDG------GAKIR----------NYYLEKR 30864
Query: 1558 NNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617
W +T+ T + + NL + YE R+ N GE S E
Sbjct: 30865 EKKQNKWISVTTEEIRE-------TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPI 30917
Query: 1618 VGEA-VPTAAPR--------NVVVHGATATQLDVTWEPPPL------------DSQNGDI 1656
++ VP AP NV VT P P+ D I
Sbjct: 30918 TPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRI 30977
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ 1716
Q +K + + ++T+ T++ + + +++G + V V A P++
Sbjct: 30978 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL---PKTLEGM 31034
Query: 1717 GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTV 1776
G A S+K ++W+ Q Y+++ V++ T
Sbjct: 31035 GAVH-ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI---------VTRSFTS 31084
Query: 1777 DVKGNSPLWLKVKDLAEGVTY---RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPII 1833
V N ++ KD V RF I KT +E +V P P GV +
Sbjct: 31085 LVFPNG---VERKDAGFYVVCAKNRFGIDQKT------VELDVADVPDP----PRGVKVS 31131
Query: 1834 VRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892
++ + W+ G IT Y++E + W + + +++ L
Sbjct: 31132 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-----GQARETRYTVINLFG 31186
Query: 1893 GVSYDFRVIAVNDYGFGTPSSPSQ 1916
SY FRVIA N +G PS PS+
Sbjct: 31187 KTSYQFRVIAENKFGLSKPSEPSE 31210
Score = 147 bits (372), Expect = 8e-35
Identities = 327/1497 (21%), Positives = 538/1497 (35%), Gaps = 177/1497 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
ND G+ ++PD + R A + + L T + V G+S+
Sbjct: 20752 NDAGVGEPAVIPD----VEIVEREMAPDFELDAELRRTLV------------VRAGLSIR 20795
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT-HISDAGTYTCLATN 479
+ G P P +TW K L + + ES +LLI P + D G + N
Sbjct: 20796 IFVPIKGRPAPEVTWTKDNINLKNRA----NIENTESFTLLIIPECNRYDTGKFVMTIEN 20851
Query: 480 SRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH--------DPRVTIRYIW 531
G + R+ P ++ T + H R+T YI
Sbjct: 20852 PAGKKSG------FVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT-NYIV 20904
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA-----GGNDSRSAHLRV 586
EK AT + S + + T + Y RV++ G + ++
Sbjct: 20905 EKREATRKSYSTATTKCHK---CTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 20961
Query: 587 RQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDP 645
+ P P+ + + + ++L W KP DG S + Y++E + + +V
Sbjct: 20962 SEAPSPPDS--LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV-- 21017
Query: 646 KATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT-----ERVSLPEEPPTAPPQN-VIA 699
K V+ L Y F++ AVN G+ + E+ LPE Q VIA
Sbjct: 21018 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIA 21077
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
N + I P+ I++ V ++ T A L + + +
Sbjct: 21078 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQR---VNFE----TTATSTILNINECVR 21130
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
+ + A N G V + +P P G + + +S + F+W+ P
Sbjct: 21131 SDSGPYPLTARNIVG---EVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPEND- 21186
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
G+ ++ E Q + T V + + + L EY V G
Sbjct: 21187 -GGVPISNYVV--EMRQTDSTTWVELATTVIRTTYKA--TRLTTGLEYQFRVKAQNRYGV 21241
Query: 880 GPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYN 936
GP T + + VPGP G + + S+ +SW EP G + GY + +E N
Sbjct: 21242 GPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERN 21301
Query: 937 RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA--MTSKGQGQVSASTISSGVPPELPG 994
+ ++ +GLT Y V A M K + + + + P + PG
Sbjct: 21302 GILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPG 21361
Query: 995 PPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDA 1053
P L NI +VTL++ +P Y G I+ ++VE + G + + L NE
Sbjct: 21362 KPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENE--- 21415
Query: 1054 RSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQPSRKI---QTLQAPP---DMAPANVSLR 1106
V L Y FR+ N G SPPS+PS I ++AP D+ + +
Sbjct: 21416 --FTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 21473
Query: 1107 TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIE 1163
A E + P P ME++ + + + K ++ + V +D T
Sbjct: 21474 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIK------IADFSTNLVNKDSTRR 21527
Query: 1164 DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEV 1223
D +T + A N G V R P GP V+ + TS ++ W
Sbjct: 21528 DSGAYT-----LTATNPGGFAKHIFNVKVLDRPG-PPEGPLAVTEV--TSEKCVLSW--F 21577
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL--TGLGKYVLYEVQVLAFTR 1281
P D G + + ++ K +T W + + +L T L K Y +V+A +
Sbjct: 21578 PPLDDGGAKIDHYIVQKR---ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNK 21634
Query: 1282 IGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRL 1340
G G P P+L P PP + S+ + W P + G + I R
Sbjct: 21635 YGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR 21694
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG--EAAEALVVTTEKRD 1398
+ + +Y +GL Y FRI A+ G +
Sbjct: 21695 DKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 21754
Query: 1399 RPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
+P PP P V D S+ ++W +P DG S + Y ++ W + +
Sbjct: 21755 KPGPPGNPRVL--DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLK 21812
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
A+S+ + L YK R+ A N G E P ++ TP
Sbjct: 21813 ATSYTITGLTENQEYKIRIYAMNSEGLGE------------------PALVPGTPKAEDR 21854
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT-LRGINNPGATWAELTSMYSMRNL 1576
+L P E +++ L + R LR F ++G P WA S+
Sbjct: 21855 ML-----PPEIELDADLRKV-VTIRACC--TLRLFVPIKGRPAPEVKWAR-DHGESLDKA 21905
Query: 1577 SRPSLTQYEL---DNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVV 1631
S S + Y L N+N+ + ++V N SS + FV V P+++
Sbjct: 21906 SIESTSSYTLLIVGNVNRFDSGKYILTVEN------SSGSKSAFVNVRVLDTPGPPQDLK 21959
Query: 1632 VHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA---ENSVKLK 1688
V T T + +TW+PP LD G KI + ++ T + + + S K+
Sbjct: 21960 VKEVTKTSVTLTWDPPLLDG------GSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVD 22013
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
L +Y V A N G G + + P P + ++T SV++SWE P+
Sbjct: 22014 QLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPE 22073
Query: 1749 FPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
G + GY +V D + TV V + + L +G Y FR+ A+
Sbjct: 22074 HDGGSRILGY-IVEMQTKGSDKWATCATVKVTEAT-----ITGLIQGEEYSFRVSAQ 22124
Score = 143 bits (361), Expect = 2e-33
Identities = 145/585 (24%), Positives = 238/585 (40%), Gaps = 50/585 (8%)
Query: 31 EPVRTQVHLEGNRLV-------LTCMAEGSWPLEFKWLHNNREL---TKFSLEYRYMITS 80
EP R LE +R+V C GS ++ W + E+ +KF + + +
Sbjct: 7303 EPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAV 7362
Query: 81 LDRTH-----AGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP 135
L+ + +G Y C N G+ T ++V F + + H + A V
Sbjct: 7363 LEMHNLSVEDSGDYTCEAHNAAGSA-SSSTSLKVKEPPIFRK-KPHPIETLKGADVHLEC 7420
Query: 136 RIASFPQPQVTWFRDGRKIPPSSRIAITLENTLV---ILSTVAPDAGRYYVQAVNDKNGD 192
+ P V+W++D R++ + I EN L IL+ A D G Y +A ND D
Sbjct: 7421 ELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSD 7480
Query: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLI------K 246
VG A P + + S V G + A P+ K
Sbjct: 7481 TC-----------VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDK 7529
Query: 247 LHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLE 306
I+ + D + +S S++ L ++AG Y C+ + + + A LSVLE
Sbjct: 7530 GEIVRESDNIWIS--YSENIATLQFSRVEPANAGKYTCQ-IKNDAGMQECF--ATLSVLE 7584
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND-GGL 365
P V++PE I + C G P S W+KD + + + N GL
Sbjct: 7585 PATIVEKPES-IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL 7643
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT--SIAPNITRGPLDSTVIDGMSVVLAC 423
+I + P D+G++ +N G+ + L V+ ++ P+ TR ++ + G SVV+ C
Sbjct: 7644 KIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMEC 7703
Query: 424 ETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGV 483
+ G+P +++W ++SG T + +L ++ SD+G YTC+ATN G
Sbjct: 7704 KVYGSPPISVSWFHEGNEISSGRKYQTTLTD-NTCALTVNMLEESDSGDYTCIATNMAGS 7762
Query: 484 DEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESH 543
DE SA L V + P V+ GT + V P ++ W K + L
Sbjct: 7763 DECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVS--WFKGSSELVPGDR 7820
Query: 544 PRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVR 587
+ L D L + + G YTC V + G S + HL ++
Sbjct: 7821 CNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Score = 142 bits (359), Expect = 3e-33
Identities = 154/583 (26%), Positives = 222/583 (38%), Gaps = 65/583 (11%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMIT-----------SLDRTHAGFY 89
G +L C GS P+ W H E TK +Y T SLD + G Y
Sbjct: 5814 GASCILECKVAGSSPISVAWFH---EKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNY 5870
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFR 149
C+ N G+ R + V SF + + V G+ + I P +V WFR
Sbjct: 5871 TCVAANVAGSDECRAV-LTVQEPPSFVKEPEPLEVLPGKNVTFTSV-IRGTPPFKVNWFR 5928
Query: 150 DGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGP 209
R++ R I E+T+ L N D S T V N G
Sbjct: 5929 GARELVKGDRCNIYFEDTVAELELF---------------NIDISQSGEYTCVVSNNAGQ 5973
Query: 210 ADPIAPTIIIPP-------KNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG- 261
A + P + SV G S + P+ + WKKDG ++
Sbjct: 5974 ASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPI---SVTWKKDGFNITTSE 6030
Query: 262 -----ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPER 316
++ L I N T DAG Y CE + V GA +S LEPP FV E E
Sbjct: 6031 KCNIVTTEKTCILEILNSTKRDAGQYSCEI---ENEAGRDVCGALVSTLEPPYFVTELE- 6086
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKLTRFRQRNDGGLQISGLVPDDT 375
+ A + V + CQ G P +++WYK D + + + N L + + +D+
Sbjct: 6087 PLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDS 6146
Query: 376 GMFQCFARNAAGEVQTSTYLAV--TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
G + C A N+ G + T + + P+ R D G+ V L C +G+ +
Sbjct: 6147 GEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQV 6206
Query: 434 TWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW 493
W + + +L L +L I T +S +G Y+C A+N G +SA L
Sbjct: 6207 CWYR-DGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT-- 6263
Query: 494 ARTRITKP-----PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR- 547
AR P P VI G A C VT +R W KD + + I
Sbjct: 6264 AREPKKSPFFDIKPVSIDVIAGESADFECHVT--GAQPMRITWSKDNKEIRPGGNYTITC 6321
Query: 548 LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLP 590
+ L I + GD G YTC+ + G D SA L V++ P
Sbjct: 6322 VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPP 6364
Score = 142 bits (358), Expect = 4e-33
Identities = 142/602 (23%), Positives = 256/602 (42%), Gaps = 41/602 (6%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKFS----LEYRYMITSL-----DRTHAGFYRC 91
G + L EG+ P+ W + E+ + S + Y I +L + +AG Y C
Sbjct: 7506 GKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTC 7565
Query: 92 IVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDG 151
++N G + + + V + E + V+ G+ + +A P+ WF+DG
Sbjct: 7566 QIKNDAG-MQECFATLSVLEPATIVEKPESIKVTTGDTCTLECT-VAGTPELSTKWFKDG 7623
Query: 152 RKIPPSSRIAITLENT---LVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGG 208
+++ ++ I+ N L I++ D+G Y + N D+ T+ +L V +
Sbjct: 7624 KELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTA---SLQVSDRTV 7680
Query: 209 PADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG------I 262
P P+ K T+ ++G+S V +EC P I + W +G +S G +
Sbjct: 7681 P-----PSFTRKLKETNGLSGSS-VVMECKVYGSPPIS--VSWFHEGNEISSGRKYQTTL 7732
Query: 263 SDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEM 322
+D+ LT+ SD+G Y C A + S A L+V EPP FV++P+
Sbjct: 7733 TDNTCALTVNMLEESDSGDYTCIATNMAGSDEC---SAPLTVREPPSFVQKPDPMDVLTG 7789
Query: 323 EKVVDIPCQAKGVPPPSITWYKDAA-VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCF 381
V KG PP S++W+K ++ +V ++ + + L++ + +G + C
Sbjct: 7790 TNVT-FTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCI 7848
Query: 382 ARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERI 441
N AG+ +T+L + + A + R D ++ G ++L +G P ++TW+K I
Sbjct: 7849 VSNEAGKASCTTHLYIKAPAKFVKRLN-DYSIEKGKPLILEGTFTGTPPISVTWKKNG-I 7906
Query: 442 LASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP 501
+ S + T +S L I + + DAG Y C N+ G D SA +++ K
Sbjct: 7907 NVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQ 7966
Query: 502 PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTW 560
+ V G AS+ C + P + + W K L + ++ N +L +Q
Sbjct: 7967 LEPVKVSVGDSASLQCQLAGTPEIGVS--WYKGDTKLRPTTTYKMHFRNNVATLVFNQVD 8024
Query: 561 SGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNS 620
D G Y C+ ++ G S S L V++ P E + + + G+
Sbjct: 8025 INDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSE 8084
Query: 621 PL 622
P+
Sbjct: 8085 PI 8086
Score = 142 bits (357), Expect = 5e-33
Identities = 172/697 (24%), Positives = 274/697 (39%), Gaps = 62/697 (8%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTK---FSLEYRYMITSL- 81
PYF EP+ + G L C +G+ + W + +L + ++++ + SL
Sbjct: 7020 PYF-IEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLV 7078
Query: 82 ----DRTHAGFYRCIVRNRMGALLQRQTEVQVAYM--GSFEEGEKHQSVSHGEAAVIRAP 135
D + G Y C N +GA+ V A F K + G
Sbjct: 7079 INKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFEC- 7137
Query: 136 RIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGD 192
RI QV+W++DG + + + + + TL IL T G+Y A N G
Sbjct: 7138 RINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPL-GT 7196
Query: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWK 252
+S + L+ V P + P + + G S T +C IK I W
Sbjct: 7197 ASSSAKLILSEHEV-------PPFFDLKPVSVDLALGESG-TFKCHVTGTAPIK--ITWA 7246
Query: 253 KDGVLLSGG------ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLE 306
KD + G + ++ LT+ DAG Y C A S+ A L V E
Sbjct: 7247 KDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA---SNIAGKDSCSAQLGVQE 7303
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR---NDG 363
PP+F+K+ E + ++ C+ G P + WYKD E+++ ++FR +
Sbjct: 7304 PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDE--TEIQESSKFRMSFVDSVA 7361
Query: 364 GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLAC 423
L++ L +D+G + C A NAAG +ST L V P + P + G V L C
Sbjct: 7362 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE-PPIFRKKPHPIETLKGADVHLEC 7420
Query: 424 ETSGAPRPAITWQKGERILASG---SVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
E G P ++W K +R L SG + F S+ I +D G Y C ATN
Sbjct: 7421 ELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLT----SIHILNVDAADIGEYQCKATND 7476
Query: 481 RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
G D + + A R K D S + G + + T + I +W KD +
Sbjct: 7477 VGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQL--QTTIEGAEPISVVWFKDKGEIVR 7534
Query: 541 ES-HPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVA 598
ES + I N +L S+ + G YTC++ + G A L V + E P +
Sbjct: 7535 ESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPES 7594
Query: 599 -TLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVP 657
++T + + T + ++ + E++ +N S K + + + + P
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNK----YKISFFNKVSGLKIINVAP 7650
Query: 658 ARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP 694
+ S + N VG KD+ SL T PP
Sbjct: 7651 SDSGVYSFEVQNPVG-----KDSCTASLQVSDRTVPP 7682
Score = 142 bits (357), Expect = 5e-33
Identities = 357/1681 (21%), Positives = 598/1681 (35%), Gaps = 218/1681 (12%)
Query: 289 RSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAV 348
RS +VP V + V+EP VK + ++ + + I G P P+ITW KD
Sbjct: 23215 RSLAVPIVAKDL---VIEPD--VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG-- 23267
Query: 349 VEVEKLTRFRQRND---GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ +++ TR + L I DD G + N G+ +T++ VT P+
Sbjct: 23268 LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-KTASIEIVTLDKPDPP 23326
Query: 406 RGPLDSTVIDGMSVVLACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+GP+ + S+ L+ T G QK + V + +L
Sbjct: 23327 KGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVV---SATVARTTLK 23383
Query: 462 ISPTHISDAGTYTCLATNSRGVDEA--SADLVVWARTRITKPP---------QDQSVIK- 509
++ + A N G A S +V + PP +D VI+
Sbjct: 23384 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 23443
Query: 510 ----GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIG 565
S V G + + +W K T+ ++ + + ++ + +
Sbjct: 23444 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQ-------NLEEGIEYEFR 23496
Query: 566 TYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIR 624
Y ++ G S R P P + V+R I L WTKP +DG S +
Sbjct: 23497 VYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITG 23554
Query: 625 YILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT---- 680
YI+E + + + + T TV GL + Y+FR+ A N G D+
Sbjct: 23555 YIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 23614
Query: 681 ---ERVSLP--EEPPTAPPQNVIASGRT-NQSIMIQWQPPPESHQNGILKGYIIRYCLAG 734
+ V LP P V+ +G T + +P P +
Sbjct: 23615 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP---------------TIEW 23659
Query: 735 LPVGYQFKNITDADVNN------LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ 788
L + + ++ N L+++D I + + A N AG + V +
Sbjct: 23660 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV---KVL 23716
Query: 789 GVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN 848
P P G V S TW SP +G + + + E V A
Sbjct: 23717 DRPGPPEGPVQVTGVTSEKCSLTW---SPPLQDGGSDISHYVVEKRETSRLAWTVVASEV 23773
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEI 906
+S+ V+ L + EY ++ G G S P L++ +PGP L + I
Sbjct: 23774 VTNSLK---VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNI 23830
Query: 907 LDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVT-LEYRVTGLTALTT 963
S+ V W P G + GY + E+ +R+ R + +T L RVTGLT
Sbjct: 23831 AKDSMTVCWNRPDSDGGSEIIGYIV--EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 23888
Query: 964 YTIEVAAMTSKGQGQVSASTI--SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGK 1020
Y V+A + G G+ S +T+ + P PGPPTN I + S+TL + +P YDG
Sbjct: 23889 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 23948
Query: 1021 TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG-- 1078
+ I ++VE + EEW ++ + R E+ L Y R+ +N VG
Sbjct: 23949 SEILGYVVEI---CKADEEEWQIVTPQTGLRVTR-FEISKLTEHQEYKIRVCALNKVGLG 24004
Query: 1079 --TSPPS--QPSRKIQTLQAPPDM-APANVSLRTASETSLWLRWMPLPEMEYNGNPESVG 1133
TS P +P K++ + D + +R + + + G P
Sbjct: 24005 EATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARI--------HIPFKGRPTP-- 24054
Query: 1134 YKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
+I +SR +G + + +I++ + + ++ N+ GS TV
Sbjct: 24055 -EITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTV--- 24110
Query: 1194 TRESVPSSG-PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL 1252
+ + + G P N++ S + W E P D V Y + +K T+ +
Sbjct: 24111 --KVLDTPGPPQNLAVKEVRKDSAFLVW-EPPIIDGGAKVKNYVI---DKRESTRKAYAN 24164
Query: 1253 VEGNSSR-SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPE 1311
V S+ S ++ L + +Y +V+A G G P + + P PP + +
Sbjct: 24165 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-PSPPGKVTLTD 24223
Query: 1312 VRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
V TS L+W+ P G +L Y + + T + E +A TGL
Sbjct: 24224 VSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNA---VVTGLSSGQE 24280
Query: 1371 YLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL----------- 1419
Y FR+ A KG + V K QP + ++A L
Sbjct: 24281 YQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPR 24340
Query: 1420 --LSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVK 1477
+SW DG P++ T E + LH N F K+ V
Sbjct: 24341 PNISWV--KDG-EPLKQTTRVNVEETATSTVLHIK--EGNKDDF----------GKYTVT 24385
Query: 1478 ATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGF 1537
ATN G + +E + + P P + V+I W+PPA
Sbjct: 24386 ATNSAGTA--TENLSVIVLEKPGPPVGPVRFDEV--SADFVVISWEPPA----------- 24430
Query: 1538 RIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRR 1594
Y G + + + + TW +++ + T ++ L
Sbjct: 24431 --------YTGGCQISNYIVEKRDTTTTTWHMVSATVAR--------TTIKITKLKTGTE 24474
Query: 1595 YEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQN 1653
Y+ R+ N G+ + V V P V + Q+ V W P D
Sbjct: 24475 YQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG-G 24533
Query: 1654 GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST 1713
I GY + E + L ++ + + K L Y V+A N G G S
Sbjct: 24534 TKIIGYHLEQKE-KNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 24592
Query: 1714 PTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSK 1772
++ + P + +T +V + W+ P + G + GY + E DG +
Sbjct: 24593 VSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGY--IVEKKDLPDG--R 24648
Query: 1773 IVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPEIEANVTTGPGEGAPGPP 1828
+ V L E Y FR+ A+ F+ + +T AP
Sbjct: 24649 WMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNAS 24708
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
P +Y I +H +G+ +V+EA + + D++ KE+ M+
Sbjct: 24709 LDP---KYKDVIVVH--AGE-------TFVLEADIRGKPIPDVVWSKDGKELEETAARME 24756
Query: 1889 I 1889
I
Sbjct: 24757 I 24757
Score = 139 bits (350), Expect = 3e-32
Identities = 336/1554 (21%), Positives = 565/1554 (36%), Gaps = 218/1554 (14%)
Query: 378 FQCFARNAAGEVQ---TSTYLAVTSIAPN----ITRGPLDSTVID-GMSVVLACETSGAP 429
F+ A N AGE + T+ + T I I G D V G + + G P
Sbjct: 15779 FRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRP 15838
Query: 430 RPAITWQ---KGERILASGSVQLPRFTPLE----SGSLLISPTHISDAGTYTCLATNSRG 482
P +W+ K ++ + G +P LE S ++I S G Y+ A N G
Sbjct: 15839 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 15898
Query: 483 VDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVT-----HDPRVTIR-YIWEKDGA 536
A+ + V + PP+D V T+ S C ++ D I+ Y+ EK
Sbjct: 15899 QKTANCRVKVMD---VPGPPKDLKVSDITRGS--CRLSWKMPDDDGGDRIKGYVIEK--R 15951
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRV-----ISAGGNDSRSAHLRVRQLPH 591
T+ ++ ++ D + + + Y RV G R +
Sbjct: 15952 TIDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIY 16010
Query: 592 APEHPVAT-LSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLA-----SVD 644
P+ P+ + + + ++L+W P DG SP+ YI+E + T A D
Sbjct: 16011 PPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 16070
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSK-----DTERVSLPE--------EPPT 691
+ TV+ LV Y+FR+ AVN G + S D +R +P E
Sbjct: 16071 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 16130
Query: 692 APPQNVIASGRTNQSIMIQW-QPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
N++A + + W + PP+ N PV Y D VN
Sbjct: 16131 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-------------PVLY------DTHVN 16171
Query: 751 NLLLED---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ--GVPTVPPGNVHAEATNS 805
L+++D L+I + + Y + + E L G P P G + E+ ++
Sbjct: 16172 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSA 16231
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
+ +W P + G K+ + E+ E + + + L +
Sbjct: 16232 DQMTLSWFPPKD------DGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGH 16285
Query: 866 EYFTSVLCFTTPGDGPR--STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG 923
EY ++ G G S P+ R VPG + S + S+ V+W+EP G
Sbjct: 16286 EYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGG 16345
Query: 924 I-LTGYRIS--------WEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
+TGY + W+ NR + + + Y+VTGL + Y V A+ +
Sbjct: 16346 SPVTGYWLEMKDTTSKRWKRVNRDPIKAM----TLGVSYKVTGLIEGSDYQFRVYAINAA 16401
Query: 975 GQGQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQ 1031
G G S + ++ P PGPP +++ S L++ P DG + ++ ++VE +
Sbjct: 16402 GVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK 16460
Query: 1032 VGVVGEG-EEWLLIHQLSNEPDAR--SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
EG EEW + + + R + V L Y FR+R VNI G P + +
Sbjct: 16461 ----EEGKEEW----EKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV 16512
Query: 1089 IQ---TLQAPPDMAPANVSLRTASETS------LWLRWMPLPEMEYNGNPESVGYKIKYS 1139
I+ L +P A+V R ++ P P + +N N ++ +
Sbjct: 16513 IEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE---- 16568
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
+ + + I++ + + + A N +G +T++ + VP
Sbjct: 16569 ---------ATIETTAISSSMVIKNCQRSHQGVYSLLAKNE--AGERKKTIIVDVLD-VP 16616
Query: 1200 SSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW--LVEGNS 1257
T A T+ S + W PE D + Y + +E D R W + +
Sbjct: 16617 GPVGTPFLAHNLTNESCKLTWFS-PEDDGGSPITNYVIEKRESDR----RAWTPVTYTVT 16671
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTT 1315
++A + GL + Y ++ A IG G + ++ R VP P + EV
Sbjct: 16672 RQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKN 16731
Query: 1316 SVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
+V L W PP G I+ Y + RL T + T + L +R+YT GLK Y +
Sbjct: 16732 TVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLL--SRKYTVKGLKEGDTYEY 16789
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
R++A G G+ + T K D PP+ + D R + L+ G R
Sbjct: 16790 RVSAVNIVGQGKPSFCTKPITCK-DELAPPTLHL----DFRDK---LTIRVGEAFALTGR 16841
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND------IGDSEF 1487
Y + P W A V + + I K + K ++ + +S
Sbjct: 16842 Y---SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 16898
Query: 1488 SEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYE 1547
S + + P +S T ++I W+PP +D + + I +E+ +
Sbjct: 16899 SRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG-GSKITNYIIEKKEVGKD 16957
Query: 1548 GLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGE 1607
W +T S + T ++ L + + Y R+ N G
Sbjct: 16958 ---------------VWMPVT--------SASAKTTCKVSKLLEGKDYIFRIHAENLYGI 16994
Query: 1608 GPSSPPQEVFVGE--AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
+ + VP AP +V T VTW P I Y + E
Sbjct: 16995 SDPLVSDSMKAKDRFRVPD-APDQPIVTEVTKDSALVTWNKP--HDGGKPITNYILEKRE 17051
Query: 1666 AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQA 1722
K ++ +L Y V+A N G G P S P + A
Sbjct: 17052 TMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIA 17111
Query: 1723 APSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGN 1781
PS P + + + T SV+++W+ P+ G + GY + Y+ D + +
Sbjct: 17112 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVG--DEEWRRANHTPESC 17169
Query: 1782 SPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
KV L +G TY+FR+ A GE P P++V+
Sbjct: 17170 PETKYKVTGLRDGQTYKFRVLA-------------VNAAGESDPAHVPEPVLVK 17210
Score = 138 bits (347), Expect = 7e-32
Identities = 278/1273 (21%), Positives = 477/1273 (37%), Gaps = 148/1273 (11%)
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNN 751
PPQ++ T S+ + W PP + I K YI+ + + + T+ +
Sbjct: 21954 PPQDLKVKEVTKTSVTLTWDPPLLDGGSKI-KNYIVEKRESTRKA---YSTVATNCHKTS 22009
Query: 752 LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
++ L +Y V A N G+G+ ++ E +PPG + ++ +
Sbjct: 22010 WKVDQLQEGCSYYFRVLAENEYGIGL-PAETAESVKASERPLPPGKITLMDVTRNSVSLS 22068
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSV 871
W P + I GY + ++ T T + + ++GL + EY V
Sbjct: 22069 WEKPEHDGGSRI-LGYIVEMQTKGSDKWATCATVK------VTEATITGLIQGEEYSFRV 22121
Query: 872 LCFTTPG-DGPRSTPQLVRTHEDVPGPVGHL---SFSEILDTSLKVSWQEPGEKNGILTG 927
G PR V + V P L +F+ + LKV G +T
Sbjct: 22122 SAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTW 22181
Query: 928 YR--ISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
++ + ++ R N T N L + + Y +++ S G+ + + I
Sbjct: 22182 HKDNVPLKQTTRVNAESTEN--NSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIV 22237
Query: 986 SGVPPELPGPPTN-LGISNIGPRSVTLQFRPG-YDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ PGPPT + + + S+TL + P YDG +SI+ ++VE + +
Sbjct: 22238 L----DKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR-------DTSTT 22286
Query: 1044 IHQLSNEPDARS-MEVPDLNPFTCYSFRMRQVNIVGTSP--PSQPSRKIQTLQAPPDMAP 1100
Q+ + AR+ ++ L Y FR+ N G S S+P+ + P
Sbjct: 22287 TWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGT 22346
Query: 1101 ANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV---E 1157
V+L +S S+ ++W E +G +GY ++ + ++ V ++ +
Sbjct: 22347 PVVTL--SSRDSMEVQWN---EPISDGGSRVIGYHLERKERN----SILWVKLNKTPIPQ 22397
Query: 1158 RDYTIEDLEEWTEYRVQVQAFNAIGSGP---WSQTVVGRTRESVPSSGPTNVSALATTSS 1214
+ LEE EY +V A N +G G S+ V R P P A+ T +
Sbjct: 22398 TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD----PCDPPGRPEAIIVTRN 22453
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA---------QLTG 1265
S+ ++W + P D + GY V KE L EG +++ ++TG
Sbjct: 22454 SVTLQWKK-PTYDGGSKITGYIVEKKE----------LPEGRWMKASFTNIIDTHFEVTG 22502
Query: 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI---WQ 1322
L + YE +V+A G S T D PP + P+ + T V ++
Sbjct: 22503 LVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFK 22562
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A G + + + +NTA +E+ + AT L + K
Sbjct: 22563 VDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF----ATSLSVKDAVRVDSGNYILKA 22618
Query: 1383 WGEAAE-ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSPVRYYTIQTR 1440
A E ++ V + DRP PP P+V V A L+W+P DG S + Y ++ R
Sbjct: 22619 KNVAGERSVTVNVKVLDRPGPPEGPVVIS-GVTAEKCTLAWKPPLQDGGSDIINYIVERR 22677
Query: 1441 ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
E W + A+V S V +L Y FR+ A N G E E +
Sbjct: 22678 ETSRLVWTVVDANVQ--TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFV 22735
Query: 1501 PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 1560
+AP VT T S+++ W+ PA D + IL G+ L +
Sbjct: 22736 VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL----------------GYVLEKRDKE 22779
Query: 1561 GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ--EVFV 1618
G W R + L + L ++ YE R+S NA G SPP +
Sbjct: 22780 GIRWTRC----HKRLIGELRL---RVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKAC 22832
Query: 1619 GEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
P N V T + + ++W P D +IQGY + + G T
Sbjct: 22833 DPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG-GCEIQGYIVEKCDVSVGEWTMCTPPT 22891
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ + +++++ L Y + A N AG G + A P V+ +L
Sbjct: 22892 GINKTNIEVEKLLEKHEYNFRICAINKAGVG----------EHADVPGPIIVE-EKLEAP 22940
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPC----------SPVDG-VSKIVTVDVKGN-SPLWL 1786
+++ E + N G ++ P VDG + +DV + + L L
Sbjct: 22941 DIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 23000
Query: 1787 KVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSS 1846
+ + Y + + T + V P P + + +++I W
Sbjct: 23001 DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSP----PVNLKVTEITKDSVSITWEP 23056
Query: 1847 G-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
G I Y++E R + + ++ + K ++ +D L+ G SY FRV A N+
Sbjct: 23057 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKN----SWKIDQLQEGCSYYFRVTAENE 23112
Query: 1906 YGFGTPSSPSQSV 1918
YG G P+ + +
Sbjct: 23113 YGIGLPAQTADPI 23125
Score = 136 bits (343), Expect = 2e-31
Identities = 147/574 (25%), Positives = 232/574 (40%), Gaps = 47/574 (8%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNREL-------TKFSLEYRYM-ITSLDRTHAGFYRCI 92
G +VL C GS P+ W + E+ + FS + ++ L+ + G Y C+
Sbjct: 6755 GASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCV 6814
Query: 93 VRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGR 152
N G+ + + V SFE+ V G + + I P +V WF+ R
Sbjct: 6815 AANVAGSD-ECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSV-IRGTPPFKVKWFKGSR 6872
Query: 153 KIPPSSRIAITLEN--TLVILSTVAP-DAGRYYVQAVNDKNGDNKTSQPITLTVENVGGP 209
++ P I+LE+ T + L V P ++G Y ND + T+ V P
Sbjct: 6873 ELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF------VKEP 6926
Query: 210 ADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG------IS 263
A T + + SV G S + LE P I + W KD L+S ++
Sbjct: 6927 A-----TFVKRLADFSVETG-SPIVLEATYTGTPPIS--VSWIKDEYLISQSERCSITMT 6978
Query: 264 DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEME 323
+ + L I T D Y C L + + A +SVLEPP F+ EP H+ A +
Sbjct: 6979 EKSTILEILESTIEDYAQYSC---LIENEAGQDICEALVSVLEPPYFI-EPLEHVEAVIG 7034
Query: 324 KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFA 382
+ + C+ G P I+WYK+ + + + +N+ L I+ + D G + C A
Sbjct: 7035 EPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKA 7094
Query: 383 RNAAGEVQTSTYLAVTS--IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGER 440
N+ G V +S L + + + P R D G V C +G+ ++W K +
Sbjct: 7095 DNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYK-DG 7153
Query: 441 ILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR---TR 497
+L L +L I T S G Y C A+N G +SA L++
Sbjct: 7154 VLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPF 7213
Query: 498 ITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHI 556
P + G + C VT I+ W KD + + ++ L N +L +
Sbjct: 7214 FDLKPVSVDLALGESGTFKCHVT--GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTV 7271
Query: 557 SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLP 590
+ GD G YTC + G DS SA L V++ P
Sbjct: 7272 LKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305
Score = 136 bits (342), Expect = 3e-31
Identities = 142/582 (24%), Positives = 240/582 (41%), Gaps = 58/582 (9%)
Query: 32 PVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNREL--------TKFSLEYRYMITSLDR 83
P++ V EG C G+ L+ W ++++ T+F Y+ I
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3408
Query: 84 THAGFYRCIVRNRMGAL------------------LQRQTEVQVAYMGSFEEGEKHQSVS 125
G Y + N +G + ++++ E+++ + + V+
Sbjct: 3409 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVA 3468
Query: 126 HGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYY 182
G A I S P + WF+ GR+I S + +I ++L IL T D G Y
Sbjct: 3469 LGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 3527
Query: 183 VQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANAR 242
+A N+ + T+ TLTV + PT + PK+ + G + + C
Sbjct: 3528 CKASNEYGSVSCTA---TLTV------TEAYPPTFLSRPKSLTTFVGKAAKFI-CTVTGT 3577
Query: 243 PLIKLHIIWKKDGVLLSGG----ISDHNRR--LTIPNPTGSDAGYYECEAVLRSSSVPSV 296
P+I+ IW+KDG LS ISD + L + N T D G Y C+A S+ +
Sbjct: 3578 PVIET--IWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKA---SNKFGAD 3632
Query: 297 VRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTR 356
+ A L +++ P F+KE E + + + K V + CQ ++TW KD + K +
Sbjct: 3633 ICQAELIIIDKPHFIKELEP-VQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYK 3691
Query: 357 FRQRND-GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID 415
+ L+I D+G + C A N AG S + V + + ++
Sbjct: 3692 ICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLP 3751
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
G S L C+ G+P +TW K + L+ + F E+ L I+ + D+G+Y+C
Sbjct: 3752 GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA-ILDITDVKVEDSGSYSC 3810
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 535
A N G D S ++V+ K + +++GT A + C V+ I W KD
Sbjct: 3811 EAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEIS--WFKDK 3868
Query: 536 ATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGG 576
+ + R+ ++ L I S D+G Y C V + G
Sbjct: 3869 KQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVG 3910
Score = 136 bits (342), Expect = 3e-31
Identities = 157/600 (26%), Positives = 242/600 (40%), Gaps = 56/600 (9%)
Query: 26 PYFKTE--PVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITS--- 80
PYF TE P+ V G+ + L C G+ + W + +L + EYR T+
Sbjct: 6079 PYFVTELEPLEAAV---GDSVSLQCQVAGTPEITVSWYKGDTKLRP-TPEYRTYFTNNVA 6134
Query: 81 ------LDRTHAGFYRCIVRNRMGALLQRQT-EVQVAYMG-SFEEGEKHQSVSHGEAAVI 132
++ +G Y C N +G + +Q + SF K + G +
Sbjct: 6135 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTL 6194
Query: 133 RAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDK 189
S P QV W+RDG + + + + TL IL T +G+Y A N
Sbjct: 6195 TCRLNGSAPI-QVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPL 6253
Query: 190 NGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLEC-VANARPLIKLH 248
G +S +T +P I P + V+AG S EC V A+P+
Sbjct: 6254 -GTASSSARLTAREPKK-------SPFFDIKPVSIDVIAGES-ADFECHVTGAQPM---R 6301
Query: 249 IIWKKDG---------VLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG 299
I W KD + G + H R L + D+G Y C+A ++ V +
Sbjct: 6302 ITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK---GDSGQYTCQA---TNDVGKDMCS 6355
Query: 300 AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKLTRFR 358
A LSV EPP+FVK+ E A+ + + + C+ G P ++W++ D+ + E K
Sbjct: 6356 AQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF 6415
Query: 359 QRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMS 418
+ L I+ +D+G + C A N G+ ST L V + P T+ P + G
Sbjct: 6416 INSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA-PPVFTQKPSPVGALKGSD 6474
Query: 419 VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLAT 478
V+L CE SG P + W K +R S + + SL I SD G Y C AT
Sbjct: 6475 VILQCEISGTPPFEVVWVK-DRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKAT 6533
Query: 479 NSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKD-GAT 537
N G D S + R K D S + G + V +++ +W KD G
Sbjct: 6534 NEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISV--VWLKDRGEV 6591
Query: 538 LGTESHPRIR-LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHP 596
+ + RI +D +L + + + G Y C++ + G SA L V + E P
Sbjct: 6592 IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP 6651
Score = 133 bits (335), Expect = 2e-30
Identities = 151/578 (26%), Positives = 242/578 (41%), Gaps = 49/578 (8%)
Query: 37 VHLEGNRLVLTCMAEGSWPLEFKWLHNN---RELTKFSLEYR-----YMITSLDRTHAGF 88
+ L G + L GS P+ W+ RE K + + +I + + G
Sbjct: 3934 IALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGK 3993
Query: 89 YRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWF 148
Y C+ N G+ E+ V E + V+ G+ A + +A P+ + W+
Sbjct: 3994 YTCLAENEAGSQTS-VGELIVKEPAKIIERAELIQVTAGDPATLEYT-VAGTPELKPKWY 4051
Query: 149 RDGRKIPPSSRIAITLENTLVIL---STVAPDAGRYYVQAVNDKNGDNKTSQPITLTVEN 205
+DGR + S + I+ +N + L S D+G+Y + N+ +S T TV +
Sbjct: 4052 KDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGS---SSCETTFTVLD 4108
Query: 206 VGGPADPIAPTIIIPPKNT-SVVAGTSEVTLEC-VANARPLIKLHIIWKKDGVLLSGGIS 263
IAP P +N SVV GT L+C +A + P+ + W KDG ++ S
Sbjct: 4109 -----RDIAPFFTKPLRNVDSVVNGTCR--LDCKIAGSLPM---RVSWFKDGKEIAA--S 4156
Query: 264 DHNR--------RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPE 315
D R L I +DAG + C A ++SV S L V EPP FV +P
Sbjct: 4157 DRYRIAFVEGTASLEIIRVDMNDAGNFTCRA---TNSVGSKDSSGALIVQEPPSFVTKPG 4213
Query: 316 RHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKLTRFRQRNDGGLQISGLVPDD 374
V + +G P +I W+K + +V ++ + L++ + D
Sbjct: 4214 SKDVLPGSAVC-LKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSD 4272
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
+G + C N AG V+ S L V A + + + G + LAC+ +G P IT
Sbjct: 4273 SGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKIT 4332
Query: 435 WQKGERILASGSVQLPRFTPLESGSLL-ISPTHISDAGTYTCLATNSRGVDEASADLVVW 493
W +R + S R + +ES ++L ++ I D+G Y C A N G D S+ ++V
Sbjct: 4333 WFANDREIKESSKH--RMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVK 4390
Query: 494 ARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT-ESHPRIRLDRNG 552
TK + V+K ++ V P I W KD L + + D
Sbjct: 4391 ESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEI--TWFKDNTILRSGRKYKTFIQDHLV 4448
Query: 553 SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLP 590
SL I + + D G Y CRV + G+ SA + +R+ P
Sbjct: 4449 SLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 4486
Score = 132 bits (331), Expect = 5e-30
Identities = 149/604 (24%), Positives = 242/604 (40%), Gaps = 45/604 (7%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRY---------MITSLDRTHAGFYRC 91
G L EG+ P+ +WL E+ + S R + +AG Y C
Sbjct: 5624 GEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYIC 5683
Query: 92 IVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDG 151
++N G + + + V E +V+ GE + ++A P+ V W++DG
Sbjct: 5684 QIKND-GGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLEC-KVAGTPELSVEWYKDG 5741
Query: 152 RKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGG 208
+ + S + + N +L ILS DAG Y Q N+ + T+ V +V
Sbjct: 5742 KLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTA------VVDVSD 5795
Query: 209 PADPIAPTIIIPPKNTSVVAGTSEVTLEC-VANARPLIKLHIIWKKDGVLLSGG------ 261
A P P+ KNT V G S + LEC VA + P+ + W + + G
Sbjct: 5796 RAVP--PSFTRRLKNTGGVLGASCI-LECKVAGSSPI---SVAWFHEKTKIVSGAKYQTT 5849
Query: 262 ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAE 321
SD+ L + + SD G Y C A + S A L+V EPP FVKEPE +
Sbjct: 5850 FSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDEC---RAVLTVQEPPSFVKEPEP-LEVL 5905
Query: 322 MEKVVDIPCQAKGVPPPSITWYKDAA-VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQC 380
K V +G PP + W++ A +V+ ++ + + L++ + +G + C
Sbjct: 5906 PGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTC 5965
Query: 381 FARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GE 439
N AG+ +T L V A + R D +V G S++L +G ++TW+K G
Sbjct: 5966 VVSNNAGQASCTTRLFVKEPAAFLKRLS-DHSVEPGKSIILESTYTGTLPISVTWKKDGF 6024
Query: 440 RILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRIT 499
I S + T ++ L I + DAG Y+C N G D A +
Sbjct: 6025 NITTSEKCNI--VTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFV 6082
Query: 500 KPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQ 558
+ G S+ C V P +T+ W K L R N +L ++
Sbjct: 6083 TELEPLEAAVGDSVSLQCQVAGTPEITVS--WYKGDTKLRPTPEYRTYFTNNVATLVFNK 6140
Query: 559 TWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDG 618
D G YTC+ ++ G S R+++ P + + +T T +G
Sbjct: 6141 VNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNG 6200
Query: 619 NSPL 622
++P+
Sbjct: 6201 SAPI 6204
Score = 130 bits (326), Expect = 2e-29
Identities = 330/1569 (21%), Positives = 558/1569 (35%), Gaps = 197/1569 (12%)
Query: 222 KNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV-LLSGGISDHNRR---LTIPNPTGS 277
K ++ AG S + V+ P + I W K G+ L S I D L +
Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPV---ITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 29510
Query: 278 DAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV-DIPCQAKGVP 336
DAG Y EA +S + V P VK E ++ + + +IP G P
Sbjct: 29511 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE--VSRDSVTITWEIPTIDGGAP 29568
Query: 337 PPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLA 396
+ K A + K T + + +ISGLV F+ N G +
Sbjct: 29569 VNNYIVEKREAAMRAFK-TVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE--- 29624
Query: 397 VTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA-------SGSVQL 449
TS A ++ PL ++ + V + T +P + G R+ +G+ +
Sbjct: 29625 -TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPL--YDGGSRLTGYVLEACKAGTERW 29681
Query: 450 PRFTPLESGSLLISPTHISDAGTYT--CLATNSRGVDEASA--------DLVVWARTRIT 499
+ L+ L + T +++ Y A N +GV E DL V ++
Sbjct: 29682 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 29741
Query: 500 KPPQDQ-SVIKGTQASMVCGVTHDPRVTIRYIWE----KDGATLGTESHPRIRLDRNGSL 554
PQ V G +V + P + + ++ + E+H ++ L
Sbjct: 29742 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV-----AKL 29796
Query: 555 HISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTK 614
I +T D G YT + + G S + + + P P P+ + ++ +I ++W
Sbjct: 29797 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIK-IDEIDATSITISWEP 29855
Query: 615 P-FDGNSPLIRYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVG 672
P DG +PL Y++E + + P W + SV T L Y FR+ A N G
Sbjct: 29856 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFG 29913
Query: 673 KGQFSKDT-----ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYI 727
G + + + +P P T +V G T + W PP E + GYI
Sbjct: 29914 IGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMT-----LTWYPP-EDDGGSQVTGYI 29967
Query: 728 IRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTL 787
+ + + + L YE V A N+ G G S+ ++ +
Sbjct: 29968 VERKEVRADRWVRVNKVP-VTMTRYRSTGLTEGLEYEHRVTAINARGSGK-PSRPSKPIV 30025
Query: 788 QGVPTVPPG---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT 844
P PPG N T T++ W+ P + + + GY LI + + E T
Sbjct: 30026 AMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVT-GY-LIEMQKVDQHEWTKCN 30083
Query: 845 ARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFS 904
P I ++ L + EY VL G G + +VPG V
Sbjct: 30084 TTPT---KIREYTLTHLPQGAEYRFRVLACNAGGPGEPA---------EVPGTVKVTEML 30131
Query: 905 EILDTSLKVSWQE----------------PGEKNGILTGYRISWEEYNRTNTRVTHYLPN 948
E D L +QE G+ I + + R +
Sbjct: 30132 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE 30191
Query: 949 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRS 1008
+ ++ G + TY + + K + I S PE P L +I RS
Sbjct: 30192 LVIKEADRGDSG--TYDLVLENKCGKKAVYIKVRVIGSPNSPEGP-----LEYDDIQVRS 30244
Query: 1009 VTLQFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
V + +RP DG I +++E + W + + + S+ V L Y
Sbjct: 30245 VRVSWRPPADDGGADILGYILERREVPKAA---W---YTIDSRVRGTSLVVKGLKENVEY 30298
Query: 1068 SFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY 1125
FR+ N G S P + + +T PP+ + +++S+ L W +
Sbjct: 30299 HFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD--- 30355
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
+G GY I+ + K + H YT+ L EY+ ++ A N +G
Sbjct: 30356 DGGSRVTGYYIE-RKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSE 30414
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
+ P S+ VV + PS P + L+ + S+ ++W E PE D +LGY V Y++
Sbjct: 30415 TSPASEPVVCKDPFDKPSQ-PGELEILSISKDSVTLQW-EKPECDGGKEILGYWVEYRQS 30472
Query: 1243 DSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT-LDDVP 1301
D+ + E + + GL + YE +V A G P + +T L
Sbjct: 30473 -GDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGE 30531
Query: 1302 GPPMGILFPEVRTT---SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P + +V T + +L Q P I Y+ L + ++ R
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-----MSSDGR 30586
Query: 1359 QYTATGL--KPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416
+T T + + E ++ A G E + L++ + P P +
Sbjct: 30587 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYY------- 30639
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY---- 1472
G+ G + + R +P+ W H + N+ + ++ + +T
Sbjct: 30640 --------GAVGSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKN 30690
Query: 1473 --------KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
K++V+ +N G + + E +Q PD+ + + S +I W+P
Sbjct: 30691 VQRKTHAGKYKVQLSNVFGTVDAILDVE----IQDKPDKPTGPIVIEALLKNSAVISWKP 30746
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
PA+D + + + E GA W ++S S+T
Sbjct: 30747 PADDG-GSWITNYVVEKCEA--------------KEGAEWQLVSSAI--------SVTTC 30783
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT-----AAPRNVVVHGATATQ 1639
+ NL ++ Y R+S N G S P EV + + AP + T
Sbjct: 30784 RIVNLTENAGYYFRVSAQNTFG---ISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 30840
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
V W+PP D I+ Y + E ++ N V T + E +KNL Y
Sbjct: 30841 CVVAWKPPASDG-GAKIRNYYLEKRE-KKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 30898
Query: 1700 VAAFNAAGD 1708
V N G+
Sbjct: 30899 VKCENLGGE 30907
Score = 129 bits (325), Expect = 2e-29
Identities = 159/625 (25%), Positives = 253/625 (40%), Gaps = 67/625 (10%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNREL------------TKFSLE 73
PYF +P V+ R+ L + G+ P+ KW +N+EL T SLE
Sbjct: 4768 PYFVEKPQSQDVN-PNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLE 4826
Query: 74 YRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIR 133
+ + T +G Y C + N +G + T ++ + +G++
Sbjct: 4827 ----LFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFE 4882
Query: 134 APRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKN 190
+I P+ +V+W+ DG +I + I+ + T I ++G Y +A ND
Sbjct: 4883 C-QITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 4941
Query: 191 GDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHII 250
S I L V+ PT I K VV S+V LEC P +
Sbjct: 4942 ---TASCSIELKVKE--------PPTFIRELKPVEVVK-YSDVELECEVTGTP--PFEVT 4987
Query: 251 WKKDG--------VLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYL 302
W K+ L+ +S N +T +P SD G Y+C S R +
Sbjct: 4988 WLKNNREIRSSKKYTLTDRVSVFNLHITKCDP--SDTGEYQCIVSNEGGSCSCSTR---V 5042
Query: 303 SVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND 362
++ EPP F+K+ E + T ++ G PP SITW KD +++ + +
Sbjct: 5043 ALKEPPSFIKKIE-NTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDS 5101
Query: 363 -GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP-LDSTVIDGMSVV 420
LQI + +G + C A+N +G + +L V A + + +D T D M+
Sbjct: 5102 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMT-- 5159
Query: 421 LACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATN 479
L C +G P + W K G++I+ S + + S I D+G YT N
Sbjct: 5160 LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNV--ASFRIQSVMKQDSGQYTFKVEN 5217
Query: 480 SRGVDEASADLVVWART---RITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
G A L V + TK + G+ M C V+ ++ + W KDG
Sbjct: 5218 DFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ--WFKDGK 5275
Query: 537 TLGTESHPRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEH 595
+ T + R+ +R+ SL ++ D YTC+V + G+D+ S L V++ P
Sbjct: 5276 EISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVK 5335
Query: 596 P----VATLSTVERRAINLTWTKPF 616
P STVE +AI L T PF
Sbjct: 5336 PGRQQAIPDSTVEFKAI-LKGTPPF 5359
Score = 129 bits (324), Expect = 3e-29
Identities = 151/641 (23%), Positives = 253/641 (39%), Gaps = 68/641 (10%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---KFSLEYRYMITSLD 82
P F + ++V +G + L C GS ++ W N+ EL K+++ + + L
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 6423
Query: 83 RTHA-----GFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRI 137
A G Y C N +G T + V F + G +++ I
Sbjct: 6424 INEASAEDSGDYICEAHNGVGDA-SCSTALTVKAPPVFTQKPSPVGALKGSDVILQC-EI 6481
Query: 138 ASFPQPQVTWFRDGRKIPPSSRIAIT---LENTLVILSTVAPDAGRYYVQAVNDKNGDN- 193
+ P +V W +D +++ S + IT + +L IL+ A D G Y+ +A N+ D
Sbjct: 6482 SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTC 6541
Query: 194 ----KTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHI 249
K +P P + +TS + G + V +P+ +
Sbjct: 6542 SCSVKFKEP----------------PRFVKKLSDTSTLIGDAVELRAIVEGFQPI---SV 6582
Query: 250 IWKKD-GVLLSGGIS------DHNRRLTIPNPTGSDAGYYECE----AVLRSSSVPSVVR 298
+W KD G ++ + D+ L + +P S++G Y C+ A +R S
Sbjct: 6583 VWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECS------ 6636
Query: 299 GAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFR 358
A L+VLEP + +++PE +T + C G P S W+KD + +
Sbjct: 6637 -AVLTVLEPARIIEKPEP-MTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHIT 6694
Query: 359 QRND-GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS--IAPNITRGPLDSTVID 415
N L+I D G++ +N+ G+ + + V+ + P+ R D I
Sbjct: 6695 FINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAIL 6754
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
G SVVL C SG+ ++ W + + SG F+ +L +S SD G YTC
Sbjct: 6755 GASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSE-NVCTLNLSLLEPSDTGIYTC 6813
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 535
+A N G DE SA L V + P V+ G + + P ++ W K
Sbjct: 6814 VAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVK--WFKGS 6871
Query: 536 ATLGTESHPRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ----LP 590
L I L D L + + + G Y+C V + G+ S + HL V++ +
Sbjct: 6872 RELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVK 6931
Query: 591 HAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSE 631
+ V T S + A T T P + Y++ SE
Sbjct: 6932 RLADFSVETGSPIVLEA-TYTGTPPISVSWIKDEYLISQSE 6971
Score = 128 bits (321), Expect = 7e-29
Identities = 170/673 (25%), Positives = 261/673 (38%), Gaps = 90/673 (13%)
Query: 1299 DVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
DVPGP + E V L W+ P G + + R + A S
Sbjct: 13088 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 13146
Query: 1359 QYTATGLKPESV-YLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
++T TGL+ V YLFR++A+ R G GE E V K D P PP + DV
Sbjct: 13147 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT--DVNR 13204
Query: 1416 RSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
V L+WEP DG + + Y I+ R+ S RW + + S+ + D ++ Y F
Sbjct: 13205 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEG-QEYSF 13263
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV+A N IG + S + + +P + L+ + T +SV ++W+PP +D + I
Sbjct: 13264 RVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPI 13323
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
L G+ + W P LT Y++ L K
Sbjct: 13324 L----------------GYIIERCEEGKDNWIRCNMKLV------PELT-YKVTGLEKGN 13360
Query: 1594 RYEIRMSVYNAVGEGPSSP------PQEVFVGEAVPTAAPRN---VVVHGATATQLDVTW 1644
+Y R+S N G S + FV + +A ++ V+V + T
Sbjct: 13361 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 13420
Query: 1645 EPPPLDSQN-GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAF 1703
P P + GD K L + VK+K L+ Y ++S +
Sbjct: 13421 YPRPTATWCFGD--------------------KVLETGDR-VKMKTLSAYAELVISPSER 13459
Query: 1704 NAAGDGPRSTPTQGQTQQ--------AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-L 1754
+ G + +T A PSAP +KF ++T SV+++WE P G L
Sbjct: 13460 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 13519
Query: 1755 EGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP---- 1810
GY + S K T + + L V DL +G Y F++ A+ GP
Sbjct: 13520 TGYVVEKREVS-----RKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARN-KCGPGEPA 13573
Query: 1811 EIEANVTTGPGEGAPGPP-GVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGL 1868
++ V P PP V R +++I + W + G I Y++E P
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 13633
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYE 1928
W + V+ + L+ G Y +RV A+N G PS P++ + A E
Sbjct: 13634 W----VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 13689
Query: 1929 EWWFLVVIALVGL 1941
FL V L GL
Sbjct: 13690 --IFLDVKLLAGL 13700
Score = 127 bits (320), Expect = 9e-29
Identities = 317/1464 (21%), Positives = 519/1464 (35%), Gaps = 187/1464 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVID------G 416
++ GL+ + F+ A N GE + LA + IA +I P LD T D G
Sbjct: 17865 RVPGLIEGNEYRFRIKAANIVGEGEPRE-LAESVIAKDILHPPEVELDVTCRDVITVRVG 17923
Query: 417 MSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
++ + G P P ITW K ++L ++ L L I +D G Y
Sbjct: 17924 QTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIIS 17982
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
A NS G + SA + V R P Q+ V T+ + C ++ WE
Sbjct: 17983 AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKEN--CTIS----------WENPLD 18027
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV---RQLPHAP 593
G+E I R + + WS T R+I A + + RV ++ P
Sbjct: 18028 NGGSEITNFIVEYRKPN---QKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGP 18084
Query: 594 ----EHPVATLSTVERRA--------------INLTWTKP-FDGNSPLIRYILEMSENNA 634
+ P+ ++ ++R + L W +P +DG SP + Y +E +
Sbjct: 18085 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 18144
Query: 635 PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE---PPT 691
+ K T V V + Y+FR+ N+ G+ + K TE V + E+ P
Sbjct: 18145 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TEEVVVKEDLQKPVL 18203
Query: 692 APPQNVIASGRTNQSIM----IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
+ + + + +I ++ +P PE + L + K T A
Sbjct: 18204 DLKLSGVLTVKAGDTIRLEAGVRGKPFPE-------VAWTKDKDATDLTRSPRVKIDTRA 18256
Query: 748 DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
D + L + V A N+AG V + V G P N+ +S
Sbjct: 18257 DSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG----PVRNLKIVDVSSDR 18312
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W+ P + G ++ + E+ E MV + + V+ L + EY
Sbjct: 18313 CTVCWDPPED------DGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY 18366
Query: 868 FTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
V G GP S P + +T D PG +++ + V W P G
Sbjct: 18367 IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKS 18426
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS--AS 982
+TGY + +E + T + +V L Y V A G G+ S +
Sbjct: 18427 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 18486
Query: 983 TISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVE--AQVGVVGEGE 1039
+ + P E PGPPTN + + S+TL + +P YDG I ++VE ++ E
Sbjct: 18487 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDE 18546
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
W + + + + V L+ Y FR+ N VG P++ I+ + +
Sbjct: 18547 GWKRCNAAA-QLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI---LE 18602
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD 1159
P + L + + +R G P + ++ G+ V +V D
Sbjct: 18603 PPEIDLDASMRKLVIVR---------AGCPIRLFAIVR-------GRPAPKVTWRKVGID 18646
Query: 1160 YTIE----DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRES--------VPSSGP-TNV 1206
+ DL + + V + SG +S T+V E + + GP +++
Sbjct: 18647 NVVRKGQVDLVDTMAFLV-IPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 18705
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGL 1266
T +S V W+ PE D V Y V +E D T + S +T L
Sbjct: 18706 KVSDVTKTSCHVSWAP-PENDGGSQVTHYIVEKREADRKTWST--VTPEVKKTSFHVTNL 18762
Query: 1267 GKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
Y +V A G G P+ P+L P PP + E+ S L W PP
Sbjct: 18763 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 18822
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
G + IT E TGLK Y FR+ A+ G
Sbjct: 18823 LRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS 18882
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL-------------LSWEPGSDGLSP 1431
EA V E +++ PP M +Q ++A L W+ G D +
Sbjct: 18883 LPREAEGV-YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEV-- 18939
Query: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491
+ S A+H A ++S I+ + S + + A N G ++
Sbjct: 18940 ----------VTSSHLAVHKAD---SSSILIIKDVTRKDSGYYSLTAENSSG----TDTQ 18982
Query: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG 1551
+ + AP ++ + + W P ED + I
Sbjct: 18983 KIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNI----------------TN 19026
Query: 1552 FTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGP 1609
+ + + W +T++ S+ + T + L + Y R+ N G E
Sbjct: 19027 YIVEKCDVSRGDW--VTALASV------TKTSCRVGKLIPGQEYIFRVRAENRFGISEPL 19078
Query: 1610 SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQR 1668
+SP VP + P+N V + V W+ P DS G I GY I E +
Sbjct: 19079 TSPKMVAQFPFGVP-SEPKNARVTKVNKDCIFVAWDRP--DSDGGSPIIGYLIERKE-RN 19134
Query: 1669 GNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPS 1728
L + + L Y + A N AG P S PT+ T + P
Sbjct: 19135 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG 19194
Query: 1729 SVKFSELTTTSVNVSWEAPQFPNG 1752
+ ++T ++V++ W P+ G
Sbjct: 19195 KPEVIDVTKSTVSLIWARPKHDGG 19218
Score = 127 bits (319), Expect = 1e-28
Identities = 190/818 (23%), Positives = 304/818 (37%), Gaps = 69/818 (8%)
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER-DYTIEDLEEW-TEYRVQVQAFNAIGS 1183
+G + +GY ++ R D KT + DR E ++T+ L++ EY +V A N +G+
Sbjct: 13116 DGGSKIIGYVVE--RRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGT 13172
Query: 1184 GPWSQT---VVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYK 1240
G +T V R++ VP P NV+ + + W E PE D + Y + +
Sbjct: 13173 GEPVETDNPVEARSKYDVPGP-PLNVTITDVNRFGVSLTW-EPPEYDGGAEITNYVIELR 13230
Query: 1241 EKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDV 1300
+K S V SA +T + + Y +V A RIG G PS + D +
Sbjct: 13231 DKTSIRWDTAMTVRAEDL-SATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPI 13289
Query: 1301 --PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P PP+ + + +SV+L W+PP G + I R N +
Sbjct: 13290 ERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPEL 13349
Query: 1359 QYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE--DVRAR 1416
Y TGL+ + YL+R++A+ + G + +E L T +P ++ +V
Sbjct: 13350 TYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVP 13409
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFR 1475
+ + P + P + + L +G R + + S + ++ + +
Sbjct: 13410 NPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAY---AELVISPSERSDKGIYT 13466
Query: 1476 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 1535
+K N + S + A AP L T SV + W+PP +D L
Sbjct: 13467 LKLENRV-----KTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDG-GSPLT 13520
Query: 1536 GFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRY 1595
G+ + RE+ + TW ++ + + P L Q + Y
Sbjct: 13521 GYVVEKREVSRK---------------TWTKVMDFVTDLEFTVPDLVQ--------GKEY 13557
Query: 1596 EIRMSVYNAVGEGPSS---PPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQ 1652
++ N G G + P + VP P NV TA + +TW+PP D
Sbjct: 13558 LFKVCARNKCGPGEPAYVDEPVNMSTPATVPDP-PENVKWRDRTANSIFLTWDPPKNDG- 13615
Query: 1653 NGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712
I+GY + RG+ +AE +++ L Y V A N G S
Sbjct: 13616 GSRIKGYIVE--RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPS 13673
Query: 1713 TPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDG 1769
PT Q Q AP VK T E P G E ++ + +
Sbjct: 13674 RPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP-KITWTKADMILK 13732
Query: 1770 VSKIVTVD-VKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPP 1828
K +T++ V S + + ++ TY +E NV PG P
Sbjct: 13733 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGP----PA 13788
Query: 1829 GVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSM 1887
I + + + W+ D G IT YV+E R +D +W L V F
Sbjct: 13789 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL----SSTVKDTNFKA 13844
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
L P Y FRV A N YG G P S + +P
Sbjct: 13845 TKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDP 13882
Score = 127 bits (318), Expect = 2e-28
Identities = 153/659 (23%), Positives = 269/659 (40%), Gaps = 54/659 (8%)
Query: 39 LEGNRLVLTCMAEGSWPLEFKWLHNNRELTK---FSLEYRYMITSL-----DRTHAGFYR 90
L G +GS P+ WL ++ E+T+ + + + SL + H G Y
Sbjct: 4498 LRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYV 4557
Query: 91 CIVRNRMGALLQRQTEV-QVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFR 149
C +N G +QR + + V + E V+ G+ A ++ + + + WF+
Sbjct: 4558 CQAKNDAG--IQRCSALLSVKEPATITEEAVSIDVTQGDPATLQV-KFSGTKEITAKWFK 4614
Query: 150 DGRKIPPSSRIAITLENT---LVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENV 206
DG+++ S+ I++ +T L I+ST D+G Y + ND + ++ L +
Sbjct: 4615 DGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLI-- 4672
Query: 207 GGPADPIAPTIIIPPKNTSVVAGTSEVTLEC-VANARPLIKLHIIWKKDGVLLSGG---- 261
I P+ K + G S + LEC VA + P+ I W KD +S
Sbjct: 4673 ------IPPSFTKKLKKMDSIKG-SFIDLECIVAGSHPI---SIQWFKDDQEISASEKYK 4722
Query: 262 --ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHIT 319
D+ L I G+D+G Y C A ++ +L+V EPP FV++P+
Sbjct: 4723 FSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQC---SGHLTVKEPPYFVEKPQSQDV 4779
Query: 320 AEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTR-FRQRNDGGLQISGLVPDDTGMF 378
+V + G P +I W+KD + ++ L++ D+G +
Sbjct: 4780 NPNTRV-QLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTY 4838
Query: 379 QCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI-DGMSVVLACETSGAPRPAITWQ- 436
C N G + L V P + P V+ +G S C+ +G P+ ++W
Sbjct: 4839 ICQLSNDVGTATSKATLFVKE-PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYL 4897
Query: 437 KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWART 496
G I A + L + IS + ++GTY C A N G S +L V
Sbjct: 4898 DGNEITAIQKHGISFIDGL--ATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 4955
Query: 497 RITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG--SL 554
+ + V+K + + C VT P + W K+ + S DR +L
Sbjct: 4956 TFIRELKPVEVVKYSDVELECEVTGTPPFEV--TWLKNNREI-RSSKKYTLTDRVSVFNL 5012
Query: 555 HISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTK 614
HI++ D G Y C V + GG+ S S + +++ P + T + ++ A T+
Sbjct: 5013 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSA---TFQS 5069
Query: 615 PFDGNSPL-IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVG 672
G+ P+ I ++ + + V ++ VD AT + ++ + S ++ A N+ G
Sbjct: 5070 TVAGSPPISITWLKDDQILDEDDNVYISFVDSVAT-LQIRSVDNGHSGRYTCQAKNESG 5127
Score = 124 bits (311), Expect = 1e-27
Identities = 299/1315 (22%), Positives = 478/1315 (36%), Gaps = 170/1315 (12%)
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
VS+ + P PP N + S++ +W+PP + + I I Y L + K
Sbjct: 14796 VSVLDTP--GPPINFVFEDIRKTSVLCKWEPPLDDGGSEI-----INYTL-------EKK 14841
Query: 743 NITDADVNNLLLED-----------LIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQG 789
+ T D +++ LI Y V A N G G S + G
Sbjct: 14842 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFG 14901
Query: 790 VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN- 848
P P + + T+++ + WN P + G ++ + E+ E + +R N
Sbjct: 14902 PPDAPDKPIVEDVTSNSML-VKWNEPK-------DNGSPILGYWLEKREVNSTHWSRVNK 14953
Query: 849 -FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
+++ V GL + Y V G G S P +T D P G +
Sbjct: 14954 SLLNALKAN-VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGP-PIPRVT 15011
Query: 908 DTS---LKVSWQEPG-EKNGILTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTAL 961
DTS +++ W+ P G + GY + ++ TN +R T + V +Y V +
Sbjct: 15012 DTSSTTIELEWEPPAFNGGGEIVGYFVD-KQLVGTNEWSRCTEKMIKVR-QYTVKEIREG 15069
Query: 962 TTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV----TLQFRPGY 1017
Y + V+A+ + G+G + + P+ P P L +S G + TL+
Sbjct: 15070 ADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP-PAVELDVSVKGGIQIMAGKTLRIPAVV 15128
Query: 1018 DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G+ V +V EGE + N + + D + + N
Sbjct: 15129 TGRP------VPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSC 15182
Query: 1078 GTSPPSQPSRKIQTLQAPP---DMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY 1134
G+ + +++ P D+ P + L W + E +G E G+
Sbjct: 15183 GSK---FAAARVEVFDVPGPVLDLKPV-----VTNRKMCLLNWS---DPEDDGGSEITGF 15231
Query: 1135 KIKYSRSDGHGKTLSHVVQ-DRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
I+ R D T ++ +R + D T L E EY+ +V A N G GP +G
Sbjct: 15232 IIE--RKDAKMHTWRQPIETERSKCDIT--GLLEGQEYKFRVIAKNKFGCGP--PVEIGP 15285
Query: 1194 TRESVPSSGPTNVSALA---TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRF 1250
P PT+ L T S++ + W E P ++ + GY + EK +P F
Sbjct: 15286 ILAVDPLGPPTSPERLTYTERTKSTITLDWKE-PRSNGGSPIQGYII---EKRRHDKPDF 15341
Query: 1251 WLVEGN--SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGIL 1308
V + S + L ++ +YE +V A IG+ PS P L + D PP L
Sbjct: 15342 ERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLP--LNVVIQDDEVPPTIKL 15399
Query: 1309 FPEVRTTSVRL-IWQP---PAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
VR ++++ +P PA G+ + +I N T T + L + + + +
Sbjct: 15400 RLSVRGDTIKVKAGEPVHIPADVTGLPMP-KIEWSKNETVIEKPT-DALQITKEEVSRSE 15457
Query: 1365 LK-----PESVY----LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRA 1415
K P++V + +TA R G + V E DRP PP V D++A
Sbjct: 15458 AKTELSIPKAVREDKGTYTVTASNRLG----SVFRNVHVEVYDRPSPPRNLAVT--DIKA 15511
Query: 1416 RSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S L+W+ P +G S + +Y I R+ + + + + + +L P Y+F
Sbjct: 15512 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 15571
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGIL 1534
RV+A N G S+ + + + P V T S+L+ W PP D +
Sbjct: 15572 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSPI 15630
Query: 1535 LGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSL--TQYELDNLNKH 1592
G+ + RE EG + S S +++ L ++ + L +
Sbjct: 15631 TGYWLEKRE---EG----------------SPYWSRVSRAPITKVGLKGVEFNVPRLLEG 15671
Query: 1593 RRYEIRMSVYNAVGEGPSSPPQ--EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+Y+ R NA G GP S P EV P P V T + + + W+PP D
Sbjct: 15672 VKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKD 15731
Query: 1651 SQNGDIQGYKIYFWE---AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG 1707
I+GY + E + E K + E V NL Y V A N AG
Sbjct: 15732 G-GSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVV--PNLKELRKYRFRVKAVNEAG 15788
Query: 1708 DGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
+ S T Q P + + P G R +
Sbjct: 15789 ESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG-----RPTPKSS 15843
Query: 1765 SPVDGVSKIVTVDVKGNSP-----------LWLKVKDLAEGVTYRFRIRAKTFTYGPEIE 1813
DG +K D + P + + + T ++ I AK
Sbjct: 15844 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 15903
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGLWDIL 1872
V G P V I R S ++ W D G I YVIE R D W
Sbjct: 15904 CRVKVMDVPGPPKDLKVSDITRGSCRLS--WKMPDDDGGDRIKGYVIEKRTIDGKAW--- 15958
Query: 1873 IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFY 1927
+ + S TF + L Y FRV A N +G G P Q A+ +P Y
Sbjct: 15959 -TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR--DPIY 16010
Score = 122 bits (307), Expect = 3e-27
Identities = 293/1394 (21%), Positives = 498/1394 (35%), Gaps = 169/1394 (12%)
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P T T + + +L W+ P DG S + YI+E E + + T
Sbjct: 16421 PPGPPFPKVTDWT--KSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 16478
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ V GL Y+FR+ AVN G G+ + T+ + + + +P + AS R +
Sbjct: 16479 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-VSPDLQLDASVRDRIVV- 16536
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLP---VGYQFKNIT---DADVNNLLLEDLIIWTN 762
H G+++ II Y ++G P V + T +A + + ++ N
Sbjct: 16537 ---------HAGGVIR--IIAY-VSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKN 16584
Query: 763 YE------IEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
+ + A N AG + V + G P P H TN + + TW +P
Sbjct: 16585 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAH-NLTNESC-KLTWFSPE 16641
Query: 817 PQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
+ I Y + E ++ VT R N V GL + YF +
Sbjct: 16642 DDGGSPITN-YVIEKRESDRRAWTPVTYTVTRQN-------ATVQGLIQGKAYFFRIAAE 16693
Query: 875 TTPGDGP---RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG------IL 925
+ G GP S ++R VP L E+ ++ ++W P G +L
Sbjct: 16694 NSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 16753
Query: 926 TGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
I E++++ TN + ++ +Y V GL TY V+A+ GQG+ S T
Sbjct: 16754 ESRLIGTEKFHKVTNDNL------LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTK 16807
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFRPG--------YDGKTSISRWLVEAQVGVVG 1036
EL P +L + L R G Y GK + + V+
Sbjct: 16808 PITCKDELAPPTLHLDFRD------KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861
Query: 1037 EGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP- 1095
+ + P ++E + + N G+ + ++ + P
Sbjct: 16862 DDRT-----HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSR---KGFCQVNVVDRPG 16913
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL-SHVVQD 1154
P + P VS ++ + + W P + +G + Y I+ GK + V
Sbjct: 16914 PPVGP--VSFDEVTKDYMVISWKPPLD---DGGSKITNYIIEKKEV---GKDVWMPVTSA 16965
Query: 1155 RVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTRESVPSSGPTNVSALATT 1212
+ + L E +Y ++ A N G S P S ++ + R VP + P T
Sbjct: 16966 SAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDA-PDQPIVTEVT 17024
Query: 1213 SSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLY 1272
S LV W++ + + + Y + +E S R + ++ L + Y
Sbjct: 17025 KDSALVTWNKPHDGGKP--ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 17082
Query: 1273 EVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
E +V A IG G PS P P+ + P PP+ + SV L WQPP G
Sbjct: 17083 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 17142
Query: 1331 -ILAYQITH-RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE 1388
IL Y + + ++ A + +Y TGL+ Y FR+ A G + A
Sbjct: 17143 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 17202
Query: 1389 ALVVTTEKRDRPQPPS----RPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPS 1444
K DR +PP M +++ ++ L LS + I+ P
Sbjct: 17203 VPEPVLVK-DRLEPPELILDANMAREQHIKVGDTLR--------LSAI----IKGVPFPK 17249
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIG------DSEFSEESESLTTLQ 1498
W A +D + + R A D G ++ ++ S+ L
Sbjct: 17250 VTWKKEDRDAPTKAR---IDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV 17306
Query: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558
P L V+ S + W+ P +D ++ + + R++
Sbjct: 17307 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDG-GSVITNYVVERRDVA------------- 17352
Query: 1559 NPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP--SSPPQEV 1616
A W+ L++ ++ + +LN+ +Y R++ N G GP +P
Sbjct: 17353 --SAQWSPLSATSKKKS--------HFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIK 17402
Query: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVK 1676
+ P P+++ T++ + W P D I GY + E Q + +K
Sbjct: 17403 ALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDG-GSPITGYLV---EYQEEGTQDWIK 17458
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST--PTQGQTQQAAPSAPSSVKFSE 1734
+ + L Y V A N G G T P + Q + PS VK E
Sbjct: 17459 FKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIE 17518
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+ P G+ S + + TV+ S + L +K+
Sbjct: 17519 GLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTVETDNFSSV-LTIKNCLRR 17576
Query: 1795 VTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGK 1851
T ++I + ++T PGPP PI + + + I W D G
Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTV---LDVPGPPTGPINILDVTPEHMTISWQPPKDDGG 17633
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
P+ Y++E + + + W + + S + L+ G Y FRV A N G G P
Sbjct: 17634 SPVINYIVEKQDTRKDTWGV----VSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPP 17689
Query: 1912 SSPSQSVPAQKANP 1925
+ +V K +P
Sbjct: 17690 LDSTPTVAKHKFSP 17703
Score = 119 bits (299), Expect = 2e-26
Identities = 335/1620 (20%), Positives = 584/1620 (36%), Gaps = 266/1620 (16%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAK--------GVPPPSITWYKDAAVVEVEK 353
++ +EP + ++ P+ + +++K V I A G PPP ITW K +
Sbjct: 29432 IAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA 29491
Query: 354 LTRFRQRNDGGLQISGLVPD-----DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP 408
+ D S L+ D D G + A N +G+ + + V T GP
Sbjct: 29492 II------DTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD-----TPGP 29540
Query: 409 LDSTVI-----DGMSVVLACET--SGAPRPAITWQKGER-------ILASGSVQLPRFTP 454
S + D +++ T GAP +K E + S L R +
Sbjct: 29541 CPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISG 29600
Query: 455 LESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQAS 514
L G++ + L N G+ E + + P V+ T++
Sbjct: 29601 LVEGTMYY----------FRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKS- 29649
Query: 515 MVCGVTHDPRVTIRYIWEK---DGAT-----------LGTESHPRIRLDRNGSLHISQTW 560
T+ WEK DG + GTE ++ + L + T
Sbjct: 29650 -----------TVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTS 29698
Query: 561 SGDIGTYTCRVISA---GGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD 617
+ Y R+ + G ++ R V + P LST+ ++ I++ +P +
Sbjct: 29699 LNEGEQYLFRIRAQNEKGVSEPRETVTAVT-VQDLRVLPTIDLSTMPQKTIHVPAGRPVE 29757
Query: 618 GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGK---- 673
L+ I A W S ++ VTV+ R + D G+
Sbjct: 29758 ----LVIPIAGRPPPAASW-FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 29812
Query: 674 -----GQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII 728
G S+ + + L + P P + T SI I W+PP E L GY++
Sbjct: 29813 LKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDAT--SITISWEPP-ELDGGAPLSGYVV 29869
Query: 729 RYCLAG----LPVG-------YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
A LPV ++F +T+ + Y VAA N G+G
Sbjct: 29870 EQRDAHRPGWLPVSESVTRSTFKFTRLTEGN-------------EYVFRVAATNRFGIGS 29916
Query: 778 Y-SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGY-------KL 829
Y S+V E PP + + + TW P + + GY +
Sbjct: 29917 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRA 29975
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
W + VTM R +GL + EY V G G S P
Sbjct: 29976 DRWVRVNKVPVTMTRYRS-----------TGLTEGLEYEHRVTAINARGSGKPSRPSKPI 30024
Query: 890 THEDVPGPVGHLSFSEILDT---SLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
D P G + DT S+ ++W P ++ G +TGY I ++ ++ +
Sbjct: 30025 VAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT 30084
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLG----- 1000
P EY +T L Y V A + G G+ + + V L P L
Sbjct: 30085 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 30144
Query: 1001 ---ISNIGPRSVTLQFRPGYDGKT-SISRWLVEAQ------VGVVGEGEEWLLIHQLSNE 1050
+ G +T+ + GK I +W E Q + E L+I + ++
Sbjct: 30145 GIFVRQGGVIRLTIPIK----GKPFPICKWTKEGQDISKRAMIATSETHTELVIKE-ADR 30199
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110
D+ + ++ N + ++ V ++G+ P+ P ++ ++ +R
Sbjct: 30200 GDSGTYDLVLENKCGKKAVYIK-VRVIGS--PNSPEGPLEY---------DDIQVR---- 30243
Query: 1111 TSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE-RDYTIEDLEEWT 1169
S+ + W P + +G + +GY ++ K + + RV ++ L+E
Sbjct: 30244 -SVRVSWRPPAD---DGGADILGYILERREVP---KAAWYTIDSRVRGTSLVVKGLKENV 30296
Query: 1170 EYRVQVQAFNAIG-SGPWS--QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 1226
EY +V A N G S P + V +T + P L T SS+ + WS P+
Sbjct: 30297 EYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSR-PKD 30355
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG--D 1284
D V GY + KE +D R + ++ +TGL Y+ +++A +G +
Sbjct: 30356 DGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYT-VTGLVPDAEYQFRIIAQNDVGLSE 30414
Query: 1285 GSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTT 1343
SP+ P++ + D P P + + SV L W+ P G IL Y + +R +
Sbjct: 30415 TSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGD 30474
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE-ALVVTTEKRDRPQP 1402
+A + + +Q+T GL + Y FR+ A+ G A+ + T+ P
Sbjct: 30475 SAWKKSNKERIKD-KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP 30533
Query: 1403 PSRPMVQQEDVR-ARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF 1461
R ++ + + LS + L +++Y + S ++ + S +H +
Sbjct: 30534 GIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVM 30593
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 1521
++ + ATN++G+ E S S LQA P P
Sbjct: 30594 TEEQEDEGV---YTCIATNEVGEVETS----SKLLLQATPQFHPGY-------------- 30632
Query: 1522 WQPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATWAELTSMY-SMR 1574
P ++K Y G G TLR G P TW + +
Sbjct: 30633 ---PLKEK----------------YYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 30673
Query: 1575 NLSRPSLTQYE---LDNLNKHR---RYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPR 1628
N++ + Y + N+ + +Y++++S N G + E+ PT
Sbjct: 30674 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLS--NVFGTVDAILDVEIQDKPDKPTGP-- 30729
Query: 1629 NVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLK 1688
+V+ ++W+PP D I Y + EA+ G + V + ++ + ++
Sbjct: 30730 -IVIEALLKNSAVISWKPPA-DDGGSWITNYVVEKCEAKEGAEWQLVSSA-ISVTTCRIV 30786
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPR---STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
NLT Y V+A N G S+ ++ P AP + +T S V+W+
Sbjct: 30787 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK 30846
Query: 1746 APQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
P G + Y L +K ++V + VK+L EG+ Y FR++ +
Sbjct: 30847 PPASDGGAKIRNYYLEKREKKQ----NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCE 30902
Score = 118 bits (296), Expect = 6e-26
Identities = 156/702 (22%), Positives = 269/702 (38%), Gaps = 67/702 (9%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT-----KFSLE---YRYM 77
P F +P V L G + T + +G+ P W + EL SLE
Sbjct: 7775 PSFVQKPDPMDV-LTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELE 7833
Query: 78 ITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRI 137
+ +D + +G Y CIV N G T + + F + S+ G+ ++
Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKA-SCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGT-F 7891
Query: 138 ASFPQPQVTWFRDGRKIPPSSRIAITLENTLVIL---STVAPDAGRYYVQAVNDKNGDNK 194
P VTW ++G + PS R IT IL S+ DAG+Y N D+
Sbjct: 7892 TGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSC 7951
Query: 195 TSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECV---ANARPLIKLHIIW 251
++Q + L +P+ ++ +AGT E+ + RP + +
Sbjct: 7952 SAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHF 8011
Query: 252 KKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLE---PP 308
+ + L D N D+G Y C+A +SV V +L+V E PP
Sbjct: 8012 RNNVATLVFNQVDIN-----------DSGEYICKA---ENSVGEVSASTFLTVQEQKLPP 8057
Query: 309 QFVKEPERHITAEMEKVVDIP----CQAKGVPPPSITWYKDAAVVEVEK--LTRFRQRND 362
F ++ ++++ V +P C G P S++WYKD ++ T F N
Sbjct: 8058 SFSRQ-----LRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLD-NT 8111
Query: 363 GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAP----NITRGPLDSTVIDGMS 418
L I G + C A N G +S L +T +I P+D+ V G S
Sbjct: 8112 ATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVV--GES 8169
Query: 419 VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLAT 478
C +G ++W K R + SG + S L + D+G YTC A
Sbjct: 8170 ADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLE-NSAHLTVLKVDKGDSGQYTCYAV 8228
Query: 479 NSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT----IRYIWEKD 534
N G D +A L + + R+ P + + + + + + RV I W K+
Sbjct: 8229 NEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKN 8286
Query: 535 GATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAP 593
+ S+ I N L + + D G YTC+V + G+ ++ + +++ P
Sbjct: 8287 NIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 8346
Query: 594 --EHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVT 651
+ + ++ E + L+ G+ P+ L+ P S +
Sbjct: 8347 VFDQHLTPVTVSEGEYVQLSC--HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLE 8404
Query: 652 VKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAP 693
++ + A S + +C ++V +K +V++ ++P AP
Sbjct: 8405 LRDVAKADSGDY-VCKASNVAGSDTTK--SKVTIKDKPAVAP 8443
Score = 115 bits (288), Expect = 5e-25
Identities = 161/653 (24%), Positives = 252/653 (38%), Gaps = 89/653 (13%)
Query: 1299 DVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN--TATVEVLAP 1355
D PGPP ++ + L W P G + I + + + + TA V
Sbjct: 18990 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKT 19049
Query: 1356 SARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP---PSRPM-VQQE 1411
S R L P Y+FR+ A+ R G E +T+ K P PS P +
Sbjct: 19050 SCR---VGKLIPGQEYIFRVRAENRFGISEP-----LTSPKMVAQFPFGVPSEPKNARVT 19101
Query: 1412 DVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFT 1470
V + ++W+ P SDG SP+ Y I+ +E S W + ++ + + + L
Sbjct: 19102 KVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRS-TEYPCAGLVEGL 19160
Query: 1471 SYKFRVKATNDIGDSEFSEESESLTT-LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK 1529
Y FR+ A N G S S+ +E +T + P P ++ VT T + + W P D
Sbjct: 19161 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLI---WARPKHDG 19217
Query: 1530 INGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQ--YELD 1587
+ I+ G+ + PG W N + + Q Y
Sbjct: 19218 GSKII----------------GYFVEACKLPGDKWVRC-------NTAPHQIPQEEYTAT 19254
Query: 1588 NLNKHRRYEIRMSVYNAVGEGPSSPPQE--VFVGEAVPTAAPRNVV------VHGATATQ 1639
L + +Y+ R AV P S P + + E VP +V V T
Sbjct: 19255 GLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVC 19314
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
LD T P+ + + G + E + + + TL L SV K+ YT
Sbjct: 19315 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGDYT----- 19367
Query: 1700 VAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
+ A N++G + + + P P+SVK +++ + +SWE P G + Y
Sbjct: 19368 ITAENSSGSKSATIKLKVLDK---PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG--------P 1810
+ S + TV + S V+ L EG Y+FRI A+ YG P
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCS-----VEKLIEGHEYQFRICAEN-KYGVGDPVFTEP 19478
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSA-IAIHWSS-GDPGKGPITRYVIEARPSDEGL 1868
I N PG P P+I + + + W D G PIT Y++E R +
Sbjct: 19479 AIAKNPYDPPGRCDP-----PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 19533
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
W + + K + T L+ G Y+FRV A+N G G PS S++ A+
Sbjct: 19534 WTKVNR---KPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYAR 19583
Score = 115 bits (287), Expect = 6e-25
Identities = 158/689 (22%), Positives = 275/689 (39%), Gaps = 62/689 (8%)
Query: 29 KTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYM---------IT 79
K EP +Q+ +G+ L C G+ P++ W N+RE+ K S ++R +T
Sbjct: 4304 KLEP--SQLLKKGDATQLACKVTGTPPIKITWFANDREI-KESSKHRMSFVESTAVLRLT 4360
Query: 80 SLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIAS 139
+ +G Y C +N G+ + + + + E E V+ +A
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGS--DHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAG 4418
Query: 140 FPQPQVTWFRDGRKIPPSSRIAITLENTLV---ILSTVAPDAGRYYVQAVNDKNGDNKTS 196
P ++TWF+D + + +++ LV IL VA DAG Y + N+ G + S
Sbjct: 4419 TPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEV-GSSICS 4477
Query: 197 QPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV 256
+TL +P P+ I ++TS + G + + + P+ + W KD
Sbjct: 4478 ARVTLR--------EP--PSFIKKIESTSSLRGGTAAFQATLKGSLPIT---VTWLKDSD 4524
Query: 257 LLSGGISDHNRRLTIPNPTGS---------DAGYYECEAVLRSSSVPSVVRGAYLSVLEP 307
++ D N R+T N S G Y C+A + + R + L ++
Sbjct: 4525 EIT---EDDNIRMTFENNVASLYLSGIEVKHDGKYVCQA----KNDAGIQRCSALLSVKE 4577
Query: 308 PQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQ 366
P + E I + + G + W+KD + + + + L+
Sbjct: 4578 PATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILK 4637
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS--IAPNITRGPLDSTVIDGMSVVLACE 424
I D+G + +N G + V I P+ T+ I G + L C
Sbjct: 4638 IISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECI 4697
Query: 425 TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
+G+ +I W K ++ +++ F + L IS +D+GTYTC ATN G +
Sbjct: 4698 VAGSHPISIQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKAGHN 4756
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHP 544
+ S L V + PQ Q V T+ + V +TI+ W KD L + +
Sbjct: 4757 QCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIK--WFKDNKELHSGAAR 4814
Query: 545 RI-RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTV 603
+ + D + SL + + D GTY C++ + G + A L V++ P + P L V
Sbjct: 4815 SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVL--V 4872
Query: 604 ERRAINLTWTKPFDGNSPL-IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662
R + T+ G + + + L+ +E A ++ +D AT + G S
Sbjct: 4873 LRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLAT-FQISGARVENSGT 4931
Query: 663 FRLCAVNDVGKGQFSKDTERVSLPEEPPT 691
+ A ND G S + + +EPPT
Sbjct: 4932 YVCEARNDAGTASCSIELK----VKEPPT 4956
Score = 114 bits (285), Expect = 1e-24
Identities = 351/1625 (21%), Positives = 576/1625 (35%), Gaps = 260/1625 (16%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARN 384
V+IP G P P++TW K +++ + F L I+ V D+G + ARN
Sbjct: 21085 VEIP--VLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 21142
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILAS 444
GEV + V I P GP+ + V +W E
Sbjct: 21143 IVGEVGDVITIQVHDI-PGPPTGPIKFDEVSSDFV------------TFSWDPPEN---D 21186
Query: 445 GSVQLPRF----------TPLESGSLLISPTHISDAGT------YTCLATNSRGVDE--A 486
G V + + T +E + +I T+ + T + A N GV
Sbjct: 21187 GGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 21246
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
SA +V ++ PP V T+ SM H+P DG + H
Sbjct: 21247 SACIVANYPFKVPGPPGTPQVTAVTKDSMTIS-WHEPL--------SDGGSPILGYHVE- 21296
Query: 547 RLDRNGSLHISQTWS-----GDIGTYTCRVISAGGNDSRSAHLRV-------RQLPHAPE 594
R +RNG L QT S G+I S+G D + RV + P P
Sbjct: 21297 RKERNGILW--QTVSKALVPGNI------FKSSGLTDGIAYEFRVIAENMAGKSKPSKPS 21348
Query: 595 HPVATLSTVE-----------RRAINLTWTKP-FDGNSPLIRYILEMSE-NNAPWTVLLA 641
P+ L ++ R + L W KP + G + YI+E + N W
Sbjct: 21349 EPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 21408
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
S + TV GL +Y+FR+ A N G + + AP V
Sbjct: 21409 S-NILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKF 21467
Query: 702 RTNQSIM----------IQWQPPPE---SHQNGILKGYIIRYCLAGLPVGYQFKNITDAD 748
+ + + +PPP S L+G A L + I D
Sbjct: 21468 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEG------TAKLEI-----KIADFS 21516
Query: 749 VNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
NL+ +D + + A N G +++ KV + P P G + S
Sbjct: 21517 -TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLD-----RPGPPEGPLAVTEVTSE 21570
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTE 866
+W P + G K+ + ++ E + + + V+ L K E
Sbjct: 21571 KCVLSWFPPLD------DGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 21624
Query: 867 YFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y V+ G G S P L P P + + I S+ V W P G
Sbjct: 21625 YIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS 21684
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + + + L Y+V+GLT Y + A + G +SA +
Sbjct: 21685 EIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAG---ISAPS 21741
Query: 984 ISSGVPPEL-----PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+S PGPP N + + S+++ + +P YDG + I+ ++VE + E
Sbjct: 21742 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEI---ALPE 21798
Query: 1038 GEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPS--QPSRKIQTLQAP 1095
+EW ++ + A S + L Y R+ +N G P+ + K + P
Sbjct: 21799 EDEWQIVTPPAG-LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 21857
Query: 1096 PDM-----APANVSLRTASETSLW--LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
P++ V++R L+ ++ P PE +K++R HG++L
Sbjct: 21858 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-------------VKWARD--HGESL 21902
Query: 1149 SHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSA 1208
+IE +T + V N SG + TV S S NV
Sbjct: 21903 DKA---------SIESTSSYT--LLIVGNVNRFDSGKYILTV---ENSSGSKSAFVNVRV 21948
Query: 1209 LAT------------TSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN 1256
L T T +S+ + W + P D + Y V EK T+ + V N
Sbjct: 21949 LDTPGPPQDLKVKEVTKTSVTLTW-DPPLLDGGSKIKNYIV---EKRESTRKAYSTVATN 22004
Query: 1257 SSRSA-QLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT 1315
+++ ++ L + Y +VLA G G P+ + + P PP I +V
Sbjct: 22005 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA-SERPLPPGKITLMDVTRN 22063
Query: 1316 SVRLIWQPPAAPNGI-ILAY--QITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
SV L W+ P G IL Y ++ + + A ATV+V + T TGL Y
Sbjct: 22064 SVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKV-----TEATITGLIQGEEYS 22118
Query: 1373 FRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-------VQQEDVRARSVLLSWEPG 1425
FR++AQ KG + + L V +D PP+ + + ED++ +
Sbjct: 22119 FRVSAQNEKGISDPRQ-LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG---- 22173
Query: 1426 SDGLSPVRYYTIQTRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGD 1484
P T +P + +++ S +N+ I D + + + VK TN G
Sbjct: 22174 ----RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGH-YVVKLTNSAG- 22227
Query: 1485 SEFSEESESLTTLQAAPDEAPT-ILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRE 1543
E E+L + PT + + T S+ + W PP D + I
Sbjct: 22228 ----EAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSI---------- 22273
Query: 1544 LLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
+ + + TW +++ + T + L Y+ R++ N
Sbjct: 22274 ------NNYIVEKRDTSTTTWQIVSATVAR--------TTIKACRLKTGCEYQFRIAAEN 22319
Query: 1604 AVGEGP--SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKI 1661
G+ +S P VP P VV ++ ++V W P D + GY +
Sbjct: 22320 RYGKSTYLNSEPTVAQYPFKVP-GPPGTPVVTLSSRDSMEVQWNEPISDG-GSRVIGYHL 22377
Query: 1662 YFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQ 1721
E + L ++ + + K L Y V+A N G G S ++ +
Sbjct: 22378 ERKE-RNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVAR 22436
Query: 1722 AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKG 1780
P + +T SV + W+ P + G + GY +V + P K ++
Sbjct: 22437 DPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGY-IVEKKELPEGRWMKASFTNIID 22495
Query: 1781 NSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTG--PGEGAPGPPGVPIIVRYSS 1838
+V L E Y FR+ A+ G E + +TG PP + + +Y
Sbjct: 22496 TH---FEVTGLVEDHRYEFRVIARN-AAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 22551
Query: 1839 AIAIH 1843
I +H
Sbjct: 22552 TIVVH 22556
Score = 112 bits (280), Expect = 4e-24
Identities = 148/591 (25%), Positives = 244/591 (41%), Gaps = 58/591 (9%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITS---LD 82
P F + + + L G L C +GS ++ W NN+EL++ + Y + S LD
Sbjct: 3737 PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILD 3796
Query: 83 RT-----HAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRI 137
T +G Y C N +G+ TE+ + SF + + + G A+++
Sbjct: 3797 ITDVKVEDSGSYSCEAVNDVGS-DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVS 3855
Query: 138 ASFPQPQVTWFRDGRKIPPSSRIAITLENTLV---ILSTVAPDAGRYYVQAVNDKNGDNK 194
+ P +++WF+D ++I S + + + +LV I S + D G Y N+
Sbjct: 3856 GTGPF-EISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANE------ 3908
Query: 195 TSQPITLTVENVGGPADPI--APTIIIPPKNTSVVAGTSEVTLE-CVANARPL----IKL 247
V G A + P + + + G VTL+ V + P+ +K
Sbjct: 3909 --------VGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKG 3960
Query: 248 HIIWKKDGVL---LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSV 304
+ ++DG + S G++ L IP+ S G Y C A + S SV L V
Sbjct: 3961 QEVIREDGKIKMSFSNGVA----VLIIPDVQISFGGKYTCLAENEAGSQTSV---GELIV 4013
Query: 305 LEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND-G 363
EP + ++ E I + G P WYKD + K R +N+
Sbjct: 4014 KEPAKIIERAEL-IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVA 4072
Query: 364 GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV--TSIAPNITRGPLDS--TVIDGMSV 419
L+ D+G + N G T V IAP T+ PL + +V++G +
Sbjct: 4073 QLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTK-PLRNVDSVVNG-TC 4130
Query: 420 VLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLAT 478
L C+ +G+ ++W K G+ I AS ++ + SL I ++DAG +TC AT
Sbjct: 4131 RLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE--GTASLEIIRVDMNDAGNFTCRAT 4188
Query: 479 NSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL 538
NS G ++S L+V P + V+ G+ + +TIR W K L
Sbjct: 4189 NSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIR--WFKGNKEL 4246
Query: 539 GTESHPRIRLDR-NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
+ I + SL + + D GTYTC+V + G SA+L V++
Sbjct: 4247 VSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE 4297
Score = 112 bits (279), Expect = 5e-24
Identities = 145/601 (24%), Positives = 232/601 (38%), Gaps = 58/601 (9%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAIT---LENTLVILSTVAPDAGRYYVQAVNDKNGDN 193
I+ PQP+++W+++ + + + E TL+++ DA Y +A ND G
Sbjct: 3262 ISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY-GVA 3320
Query: 194 KTSQPITLTVENVGGPAD--PIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIW 251
TS +++ V V P P+ P II P +V + +C + L + W
Sbjct: 3321 TTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL---KVSW 3377
Query: 252 -KKDGVLLSGGIS-----DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVL 305
KD + + +L I D G Y A S++V V A LS+
Sbjct: 3378 YSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA---SNAVGQVSSTANLSLE 3434
Query: 306 EPPQFVKEP-ERHITAEMEK-----------------VVDIPCQAKGVPPPSITWYKDAA 347
P + E E+ I EM+ + C+ + P W+K
Sbjct: 3435 APESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGR 3494
Query: 348 -VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT-SIAPNIT 405
+ E +K + + L+I D G + C A N G V + L VT + P
Sbjct: 3495 EIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFL 3554
Query: 406 RGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL-ISP 464
P T G + C +G P WQK L+ R + E+ +L +S
Sbjct: 3555 SRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNW--RISDAENKHILELSN 3612
Query: 465 THISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPR 524
I D G Y+C A+N G D A+L++ + K + + + C V D +
Sbjct: 3613 LTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRK 3672
Query: 525 VTIRYIWEKDGATLGTESHPRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
VT+ W KDG L +I D+ +L I D GTY C + G+ S SA
Sbjct: 3673 VTVT--WSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSAT 3730
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYI-----LEMSENNAPWTV 638
+ VR+ P + + + + L SP+I+ E+SE+N TV
Sbjct: 3731 VTVREPPSFVKKVDPSYLMLPGESARLHCKLK---GSPVIQVTWFKNNKELSESN---TV 3784
Query: 639 LLASVDPKA-TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNV 697
+ V+ +A +T + + SY AVNDVG S + P T P ++
Sbjct: 3785 RMYFVNSEAILDITDVKVEDSGSYSCE--AVNDVGSDSCSTEIVIKEPPSFIKTLEPADI 3842
Query: 698 I 698
+
Sbjct: 3843 V 3843
Score = 110 bits (275), Expect = 2e-23
Identities = 139/629 (22%), Positives = 246/629 (39%), Gaps = 71/629 (11%)
Query: 30 TEPVRTQVHLEGNRLV-------LTCMAEGSWPLEFKWLHNNRELTKFSLEYR------- 75
TEP + LE +++V L C GS + W N EL S +YR
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPA-SDKYRMTFIDSV 5478
Query: 76 --YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEK-HQSVSHGEAAVI 132
+ +L +G + C +N G+ T+V V F +++ + E ++
Sbjct: 5479 AVIQMNNLSTEDSGDFICEAQNPAGS-TSCSTKVIVKEPPVFSSFPPIVETLKNAEVSL- 5536
Query: 133 RAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDK 189
++ P +V W++D R++ S + I +N ++ IL+ D G Y+ +A N+
Sbjct: 5537 -ECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEV 5595
Query: 190 NGDN-----KTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPL 244
D K +P P + + +VVAG + A+P+
Sbjct: 5596 GSDTCVCTVKLKEP----------------PRFVSKLNSLTVVAGEPAELQASIEGAQPI 5639
Query: 245 IKLHIIWKKDGVLLSGGIS----DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA 300
+ K++ + S I ++ L ++AG Y C+ ++ A
Sbjct: 5640 FVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENM---A 5696
Query: 301 YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
L VLEP V E +T + + + C+ G P S+ WYKD ++ + +F
Sbjct: 5697 TLMVLEPAVIV-EKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFY 5755
Query: 361 ND-GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT--SIAPNITRGPLDSTVIDGM 417
N L+I + D G + +N G+ + + V+ ++ P+ TR ++ + G
Sbjct: 5756 NKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGA 5815
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
S +L C+ +G+ ++ W + + SG+ F+ +L ++ SD G YTC+A
Sbjct: 5816 SCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSD-NVCTLQLNSLDSSDMGNYTCVA 5874
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
N G DE A L V K P+ V+ G + + P + W +
Sbjct: 5875 ANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVN--WFRGARE 5932
Query: 538 LGTESHPRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ----LPHA 592
L I D L + G YTC V + G S + L V++ L
Sbjct: 5933 LVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRL 5992
Query: 593 PEHPVATLSTVERRA-------INLTWTK 614
+H V ++ + I++TW K
Sbjct: 5993 SDHSVEPGKSIILESTYTGTLPISVTWKK 6021
Score = 110 bits (274), Expect = 2e-23
Identities = 129/573 (22%), Positives = 230/573 (40%), Gaps = 52/573 (9%)
Query: 40 EGNRLVLTCMAEGSWPLEFKWLHNNRELTK---FSLEYR-----YMITSLDRTHAGFYRC 91
E + + L C+ G+ L+ KWL + +++ FS+ + + I S+ + +G Y
Sbjct: 5154 EKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTF 5213
Query: 92 IVRNRMGA------LLQRQTEVQVAYMGSFEEGEKHQSVS-HGEAAVIRAPRIASFPQPQ 144
V N G+ L + ++ + +K S H E V + I++
Sbjct: 5214 KVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISA----- 5268
Query: 145 VTWFRDGRKIPPSSRIAITLENTLVIL--STVAPDAGRYYVQAVNDKNGDNKTSQPITLT 202
WF+DG++I S++ + V L + + + Y V++ GD+ S +T+
Sbjct: 5269 -QWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Query: 203 VENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV-LLSG- 260
+P P+ ++ P + S V + + P K+ W KD V L+SG
Sbjct: 5328 --------EP--PSFLVKPGRQQAIPD-STVEFKAILKGTPPFKIK--WFKDDVELVSGP 5374
Query: 261 ----GISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPER 316
G+ L + + S G Y C ++ V S L V EPP+FVK+ E
Sbjct: 5375 KCFIGLEGSTSFLNLYSVDASKTGQYTCHV---TNDVGSDSCTTMLLVTEPPKFVKKLEA 5431
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR---NDGGLQISGLVPD 373
+ + C+ G P + W+++ E+ ++R + +Q++ L +
Sbjct: 5432 SKIVKAGDSSRLECKIAGSPEIRVVWFRNEH--ELPASDKYRMTFIDSVAVIQMNNLSTE 5489
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D+G F C A+N AG ST + V P + P + V L CE SG P +
Sbjct: 5490 DSGDFICEAQNPAGSTSCSTKVIVKE-PPVFSSFPPIVETLKNAEVSLECELSGTPPFEV 5548
Query: 434 TWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW 493
W K +R L S + S+ I SD G Y C A N G D + +
Sbjct: 5549 VWYKDKRQLRSSKKYKIASKNFHT-SIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLK 5607
Query: 494 ARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS 553
R +V+ G A + + + ++++ EK+ +E+ ++ +
Sbjct: 5608 EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVAT 5667
Query: 554 LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
L ++ + G Y C++ + GG A L V
Sbjct: 5668 LQFAKAEPANAGKYICQIKNDGGMRENMATLMV 5700
Score = 108 bits (269), Expect = 7e-23
Identities = 140/589 (23%), Positives = 219/589 (37%), Gaps = 50/589 (8%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---KFSLEY-----RYM 77
P F +P V G C G+ + W + E+T K + + +
Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 4920
Query: 78 ITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRI 137
I+ ++G Y C RN G E++V +F K V + +
Sbjct: 4921 ISGARVENSGTYVCEARNDAGTA-SCSIELKVKEPPTFIRELKPVEVVKYSDVELEC-EV 4978
Query: 138 ASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAGRYYVQAVNDKNGDNK 194
P +VTW ++ R+I S + +T + L I D G Y V+++ G
Sbjct: 4979 TGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC-IVSNEGGSCS 5037
Query: 195 TSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKD 254
S + L +P P+ I +NT+ V +S VA + P+ I W KD
Sbjct: 5038 CSTRVALK--------EP--PSFIKKIENTTTVLKSSATFQSTVAGSPPI---SITWLKD 5084
Query: 255 GVLLSG------GISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP 308
+L D L I + +G Y C+A S A+L V EP
Sbjct: 5085 DQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCY---AFLLVQEPA 5141
Query: 309 QFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAA-VVEVEKLTRFRQRNDGGLQI 367
Q V++ + E + + + C G P + W KD +V + + N +I
Sbjct: 5142 QIVEKAKSVDVTEKDPMT-LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRI 5200
Query: 368 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVT--SIAPNITRGPLDSTVIDGMSVVLACET 425
++ D+G + N G YL V +I P+ T+ + G S+ + C+
Sbjct: 5201 QSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKV 5260
Query: 426 SGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
SG+ + W K G+ I S +L S SL ++ + D YTC +N G D
Sbjct: 5261 SGSLPISAQWFKDGKEISTSAKYRLVCHE--RSVSLEVNNLELEDTANYTCKVSNVAGDD 5318
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHP 544
S L V P Q I + + P I+ W KD L S P
Sbjct: 5319 ACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIK--WFKDDVEL--VSGP 5374
Query: 545 RIRLDRNGSLHISQTWSGDI---GTYTCRVISAGGNDSRSAHLRVRQLP 590
+ + GS +S D G YTC V + G+DS + L V + P
Sbjct: 5375 KCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPP 5423
Score = 105 bits (263), Expect = 4e-22
Identities = 280/1353 (20%), Positives = 493/1353 (36%), Gaps = 159/1353 (11%)
Query: 621 PLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT 680
P + + + +AP T V P + + ++ + L N G S
Sbjct: 17246 PFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSV-- 17302
Query: 681 ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQ 740
+V + ++P PP+++ S S + W+ P + + I + R +A Q
Sbjct: 17303 -KVLVLDKP--GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASA----Q 17355
Query: 741 FKNIT-DADVNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGN 797
+ ++ + + + L Y VAA N G G V + K + P PP +
Sbjct: 17356 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 17415
Query: 798 VHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF 857
+H + T + WN P + I GY L+ ++ E ++ N +
Sbjct: 17416 LHHVDVDKTEVSLVWNKPDRDGGSPIT-GY-LVEYQEEGTQDWIKFKTVTNLEC-----V 17468
Query: 858 VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVS--- 914
V+GL++ Y V G G T + E + P L I +K
Sbjct: 17469 VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTV 17528
Query: 915 ---------------WQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLT 959
W G + Y + + ++ T + + L T EY++T
Sbjct: 17529 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT-IKNCLRRDTGEYQITVSN 17587
Query: 960 ALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN-LGISNIGPRSVTLQFRPGYD 1018
A + T+ V ++PGPPT + I ++ P +T+ ++P D
Sbjct: 17588 AAGSKTVAVHLTVL-----------------DVPGPPTGPINILDVTPEHMTISWQPPKD 17630
Query: 1019 -GKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G + + ++VE Q + W ++ S++ +++P L Y FR+R N +
Sbjct: 17631 DGGSPVINYIVEKQDT---RKDTWGVVSSGSSKT---KLKIPHLQKGCEYVFRVRAENKI 17684
Query: 1078 GTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIK 1137
G PP + + + P P + +E + + W LP+ + G GY ++
Sbjct: 17685 GVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSD--GGSPITGYYME 17741
Query: 1138 YSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTR 1195
R + GK + + + + L E Y +V A N G S P S + R
Sbjct: 17742 --RREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR 17799
Query: 1196 ESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG 1255
P P N + + + W++ P +D +LGY V ++ + R E
Sbjct: 17800 PIKPPGPPINPKLKDKSRETADLVWTK-PLSDGGSPILGYVVECQKPGTAQWNRINKDEL 17858
Query: 1256 NSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVR 1313
+ ++ GL + Y ++ A +G+G P ++ + + P + + +V
Sbjct: 17859 IRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVI 17918
Query: 1314 TT----SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPES 1369
T ++R++ + P I + ++ ++ L Q
Sbjct: 17919 TVRVGQTIRILARVKGRPEPDI-TWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977
Query: 1370 VYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDG 1428
Y+ I+A+ G + + + V DRP P V +V + +SWE P +G
Sbjct: 17978 KYI--ISAKNSSGHAQGSAIVNVL----DRPGPCQNLKVT--NVTKENCTISWENPLDNG 18029
Query: 1429 LSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 1488
S + + ++ R+ W++ ++ V+ I L Y FRV A N +G
Sbjct: 18030 GSEITNFIVEYRKPNQKGWSIVASDVTKR---LIKANLLANNEYYFRVCAENKVGVGPTI 18086
Query: 1489 EESESLTTLQAA--PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLY 1546
E + + P E P L + T V ++W+ P D L + + R
Sbjct: 18087 ETKTPILAINPIDRPGE-PENLHIADKGKTFVYLKWRRPDYDG-GSPNLSYHVERR---- 18140
Query: 1547 EGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG 1606
L+G ++ W E S++ T Y +D +++ YE R+ N G
Sbjct: 18141 -------LKGSDD----W-ERVHKGSIKE------THYMVDRCVENQIYEFRVQTKNEGG 18182
Query: 1607 EGPSSPPQEVFVGEAVPT-------AAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGY 1659
E +EV V E + + V + V +P P + D
Sbjct: 18183 ESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDAT 18242
Query: 1660 KIYFWEAQRGNLTERVKTLFLAENS----VKLKNLTGYTAYMVSVAAFNAAGDGPRSTPT 1715
+ + RVK A++S K K G Y+V+ A N AG
Sbjct: 18243 DL--------TRSPRVKIDTRADSSKFSLTKAKRSDG-GKYVVT--ATNTAGSFVAYATV 18291
Query: 1716 QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV--SKI 1773
+ P ++K ++++ V W+ P+ G E + E C V +
Sbjct: 18292 NVLDK---PGPVRNLKIVDVSSDRCTVCWDPPEDDGGC-EIQNYILEKCETKRMVWSTYS 18347
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGE----GAPGPP 1828
TV G + V L EG Y FR+RA+ GP E+ + G P PP
Sbjct: 18348 ATVLTPGTT-----VTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPP 18402
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
V + + + + D GK IT Y +E + W + K + +
Sbjct: 18403 EVTKVSKEEMTVVWNPPEYDGGKS-ITGYFLEKKEKHSTRWVPVNKSA---IPERRMKVQ 18458
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
L P Y FRV A N+ G G PS PS+ V A+
Sbjct: 18459 NLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 18491
Score = 100 bits (248), Expect = 2e-20
Identities = 154/690 (22%), Positives = 263/690 (38%), Gaps = 56/690 (8%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRA- 134
+ +TSLD +R +N++G + + + E E S + ++RA
Sbjct: 18562 FTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAG 18621
Query: 135 ------PRIASFPQPQVTWFRDG--RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAV 186
+ P P+VTW + G + + LVI ++ D+G+Y + V
Sbjct: 18622 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLV 18681
Query: 187 NDKNGDNKTSQPITLTVENVGGPADPIAPTIII---------PPKNTSVVAGTSEVTLEC 237
N + + + + V + GP + + + PP+N T + +
Sbjct: 18682 NPAG---EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKR 18738
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI--SDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPS 295
A+ + + KK ++ + +++ R+T N G + VL S
Sbjct: 18739 EADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP--- 18795
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPS--ITWYKDAAVVEVEK 353
LS +PP+ ++ E +T + +P G IT Y++ ++
Sbjct: 18796 ------LSEPDPPRKLEVTE--MTKNSATLAWLPPLRDGGAKIDGYITSYREEEQ-PADR 18846
Query: 354 LTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIAPNITRGPL 409
T + D L ++GL F+ ARNA G Y A + P P
Sbjct: 18847 WTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPE 18906
Query: 410 DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
T+ G + + G P P W+KGE + + S L S L+I D
Sbjct: 18907 QITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS-HLAVHKADSSSILIIKDVTRKD 18965
Query: 470 AGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--I 527
+G Y+ A NS G D +VV +PP D S I S+ + + +
Sbjct: 18966 SGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 19025
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG-NDSRSAHLRV 586
YI EK + G + + S + + G + R + G ++ ++ V
Sbjct: 19026 NYIVEKCDVSRGDWVTALASVTKT-SCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 19084
Query: 587 RQLPHA-PEHPV-ATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
Q P P P A ++ V + I + W +P DG SP+I Y++E E N+ V
Sbjct: 19085 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 19144
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS--LPEEPPTAPPQNVIASG 701
++T GLV Y FR+ A+N G SK TE V+ +P +PP P +
Sbjct: 19145 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDV--- 19201
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYC 731
T ++ + W P + I+ GY + C
Sbjct: 19202 -TKSTVSLIWARPKHDGGSKII-GYFVEAC 19229
Score = 95.9 bits (237), Expect = 4e-19
Identities = 141/605 (23%), Positives = 223/605 (36%), Gaps = 65/605 (10%)
Query: 26 PYF--KTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNREL---TKFSLEYRYMITS 80
PYF + EPV+ V G+ L C G+ + W + +L T + + +R + +
Sbjct: 7961 PYFVKQLEPVKVSV---GDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVAT 8017
Query: 81 L-----DRTHAGFYRCIVRNRMGALLQRQ--TEVQVAYMGSFEEGEKHQSVSHGEAAVIR 133
L D +G Y C N +G + T + SF + + G V
Sbjct: 8018 LVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFD 8077
Query: 134 APRIASFPQPQVTWFRDGRKIPPSSRIAIT-LENT--LVILSTVAPDAGRYYVQAVNDKN 190
S P V+W++DG+ + S + + L+NT L I T AG+Y A N
Sbjct: 8078 CAISGSEPI-SVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPI- 8135
Query: 191 GDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHII 250
G +S + LT G P + P V G S EC IK +
Sbjct: 8136 GSASSSARLILTE----GKNPPFFDIRLAP---VDAVVGES-ADFECHVTGTQPIK--VS 8185
Query: 251 WKKDG-VLLSGG-----ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSV 304
W KD + SGG +++ LT+ D+G Y C AV +
Sbjct: 8186 WAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 8245
Query: 305 LEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG- 363
L PP F K + + + G P ++ WYK+ ++ +N+
Sbjct: 8246 LIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTL 8305
Query: 364 GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA--PNITRGPLDSTVIDGMSVVL 421
LQ+ +D G++ C N AG ++ + + P + TV +G V L
Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQL 8365
Query: 422 ACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHIS--DAGTYTCLATN 479
+C G+ I W K R + F SG+ ++ ++ D+G Y C A+N
Sbjct: 8366 SCHVQGSEPIRIQWLKAGREIKPSDRCSFSFA---SGTAVLELRDVAKADSGDYVCKASN 8422
Query: 480 SRGVDE---------------ASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPR 524
G D A+ V R PQ V++ T A+ + V DP
Sbjct: 8423 VAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPI 8482
Query: 525 VTIRYIWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRS 581
++ W K G R+ + + G L I T D G Y C + G +
Sbjct: 8483 PNVK--WTK-GKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESN 8539
Query: 582 AHLRV 586
+L+V
Sbjct: 8540 VNLQV 8544
Score = 94.0 bits (232), Expect = 1e-18
Identities = 163/705 (23%), Positives = 268/705 (38%), Gaps = 83/705 (11%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHA-----------GFY 89
G L+C G + KW +EL + +Y ++S RTH G Y
Sbjct: 30547 GEAAQLSCQIVGRPLPDIKWYRFGKELIQ---SRKYKMSSDGRTHTLTVMTEEQEDEGVY 30603
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASF--PQPQVTW 147
CI N +G + + +++ + F G + +G + P P +TW
Sbjct: 30604 TCIATNEVGEV-ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTW 30662
Query: 148 FRDGRKIPPSSRIAITLENTLVILSTVAPD------AGRYYVQAVNDKNGDNKTSQPITL 201
F G+K+ +S IT+ENT V + AG+Y VQ N + L
Sbjct: 30663 FH-GQKLLQNSE-NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG-----TVDAIL 30715
Query: 202 TVENVGGPADPIAPTIIIPP-KNTSVVA-------GTSEVTLECVANARPLIKLHIIWKK 253
VE P P P +I KN++V++ G S +T V K W+
Sbjct: 30716 DVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEA--KEGAEWQ- 30772
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE 313
L+S IS R+ N T +AGYY + + + + + + +++ P ++
Sbjct: 30773 ---LVSSAISVTTCRIV--NLT-ENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP--FEK 30824
Query: 314 PERHITAEMEKVVDIPCQAKGVPPPSI------TWYKDAAVVEVEKLTRF--RQRNDGGL 365
P + V C PP S +Y + + K + +
Sbjct: 30825 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 30884
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLA-------VTSIAPNITRGPLDSTVIDGMS 418
+ L+ F+ N GE + S V AP+ + V +
Sbjct: 30885 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 30944
Query: 419 VVLACETSGAPRPAITW-QKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTC 475
L C+ +G P+P + W ++G+ I+A G R + G L+I+ DA Y
Sbjct: 30945 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY--RIQEFKGGYHQLIIASVTDDDATVYQV 31002
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSV-----IKGTQASMVCGVTHDPRVTIRYI 530
ATN G +A L V +I P + + ++G S+ + P I
Sbjct: 31003 RATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVIT-- 31060
Query: 531 WEKDGATLGTESHPRIRLDRNGSLHI--SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
W+K + H ++ + R+ + + + D G Y + G D ++ L V
Sbjct: 31061 WQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVAD 31120
Query: 589 LPHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKA 647
+P P +S V R ++NLTWT+P DG S + YI+E A + + +
Sbjct: 31121 VPDPPRG--VKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RE 31176
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 692
T TV L SYQFR+ A N G + S+ +E E+ A
Sbjct: 31177 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 31221
Score = 90.5 bits (223), Expect = 2e-17
Identities = 155/724 (21%), Positives = 278/724 (38%), Gaps = 106/724 (14%)
Query: 311 VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG---GLQI 367
+++ + +T ++ + + CQ G P P I WY+ E+ + +++ +DG L +
Sbjct: 30535 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGK--ELIQSRKYKMSSDGRTHTLTV 30592
Query: 368 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS- 426
+D G++ C A N GEV+TS+ L + + PL + L
Sbjct: 30593 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 30652
Query: 427 -GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE 485
G P PA+TW G+++L + T + ++ + + AG Y +N G +
Sbjct: 30653 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVD 30712
Query: 486 ASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTI-RYIWEKDGATLGTESH 543
A D+ + + + T P ++++K + D I Y+ EK A G E
Sbjct: 30713 AILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE-- 30770
Query: 544 PRIRLDRNGSLHISQTWSGDIGTYTCRV------------ISAGGNDSRSAHLRVRQL-- 589
Q S I TCR+ +SA S L V +
Sbjct: 30771 -------------WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 30817
Query: 590 -------PHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
P AP P T++ V + + + W P DG + + Y LE E + +
Sbjct: 30818 IKSPFEKPGAPGKP--TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVT 30875
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP------Q 695
+ + + T +VK L+ Y+FR+ N G+ ++S+ +E ++ + P P +
Sbjct: 30876 TEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELR 30935
Query: 696 NVIASGRTNQSIMIQWQPPPESHQNGILKGYI---------IRYCLAGLPVGYQ---FKN 743
N+ ++N +++ + H I+K Y ++Y + GY +
Sbjct: 30936 NLNVRYQSNATLVCK----VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIAS 30991
Query: 744 ITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEAT 803
+TD D + TN V+ S + V + TL+G+ G VHA
Sbjct: 30992 VTDDDATVYQVRA----TNQGGSVSGTASLEVEVPAKIHLPKTLEGM-----GAVHALRG 31042
Query: 804 NSTTIRFTWNA-PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS--- 859
+I+ ++ P P +I W+ Q+ ++ ++Q + F S
Sbjct: 31043 EVVSIKIPFSGKPDP-----------VITWQKGQD----LIDNNGHYQVIVTRSFTSLVF 31087
Query: 860 --GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
G+++ F V+C + T +L DVP P + S++ S+ ++W E
Sbjct: 31088 PNGVERKDAGF-YVVCAKNRFGIDQKTVEL--DVADVPDPPRGVKVSDVSRDSVNLTWTE 31144
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P G +T Y + E+ T R Y V L T+Y V A G
Sbjct: 31145 PASDGGSKITNYIV--EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGL 31202
Query: 977 GQVS 980
+ S
Sbjct: 31203 SKPS 31206
Score = 85.9 bits (211), Expect = 4e-16
Identities = 117/518 (22%), Positives = 207/518 (39%), Gaps = 71/518 (13%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKF-SLEYRYM-------ITSLDRTHAGFYRCI 92
G +V C GS P+ W + + L +++ ++ I DR+ AG Y C
Sbjct: 8071 GLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCT 8130
Query: 93 VRNRMGALLQRQTEVQVAYMGS--FEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRD 150
N +G+ + F+ GE+A + P +V+W +D
Sbjct: 8131 ATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPI-KVSWAKD 8189
Query: 151 GRKIPPSSRIAIT-LENT--LVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVG 207
R+I + I+ LEN+ L +L D+G+Y AVN+ D+ T+Q L ++
Sbjct: 8190 SREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQ---LNIKER- 8245
Query: 208 GPADPIAPTIIIPPKNTSVVAGTSEVT------LEC-VANARPLIKLHIIWKKDGVLLSG 260
+IPP T ++ T E T LE VA ++P+ + W K+ + +
Sbjct: 8246 ----------LIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPIT---VAWYKNNIEIQ- 8291
Query: 261 GISDHNRRLTIPNPT---------GSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP--PQ 309
N +T N T +DAG Y C+ S+ S + + + + EP P
Sbjct: 8292 --PTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKV---SNDAGSALCTSSIVIKEPKKPP 8346
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQIS 368
+ +T + V + C +G P I W K ++ F + L++
Sbjct: 8347 VFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELR 8406
Query: 369 GLVPDDTGMFQCFARNAAGEVQTSTYLAVT---SIAPNITRGPLDST-----------VI 414
+ D+G + C A N AG T + + + ++AP + +D V+
Sbjct: 8407 DVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVV 8466
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
+ + + G P P + W KG+ + ++ + L I T +D+G Y
Sbjct: 8467 EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYR 8526
Query: 475 CLATNSRGVDEASADLVVWARTRITKPPQD-QSVIKGT 511
C+A N G E++ +L V R + K D ++++K T
Sbjct: 8527 CVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKT 8564
Score = 83.6 bits (205), Expect = 2e-15
Identities = 113/486 (23%), Positives = 191/486 (39%), Gaps = 71/486 (14%)
Query: 120 KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAP 176
K +V+ GE A S+ V W+ G+K+ PS ++ E +TL +
Sbjct: 12203 KDVTVTAGETATFDCE--LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 12260
Query: 177 DAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
DAG + A + K N L V+ P P V + LE
Sbjct: 12261 DAGEVQLTAKDFKTHAN-------LFVKE--------PPVEFTKPLEDQTVEEGATAVLE 12305
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-----ISDHN-RRLTIPNPTGSDAGYYECEAVLRS 290
C + + W K+G + ++D R+L I + T D Y C+A
Sbjct: 12306 CEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK 12362
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVE 350
+S L+V+ P P + +++ C+ + W+KD A E
Sbjct: 12363 TS-------CNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVKWFKDGA--E 12412
Query: 351 VEKLTRFRQRNDGGLQI---SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRG 407
++K ++ + G ++I + + DD + C R A +TS L V T+
Sbjct: 12413 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLEEEAVFTKN 12468
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKG-ERILASGSVQLPRFTPLESGSLLISPTH 466
+ V + ++ L CE S P + W KG E I+ +G ++ T L+I H
Sbjct: 12469 LANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEI--LTEGRKRILVIQNAH 12525
Query: 467 ISDAGTYTCLATNSR-----GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
+ DAG Y C +SR V E +A+ + PQ+ +++G +A VC ++
Sbjct: 12526 LEDAGNYNCRLPSSRTDGKVKVHELAAEFI--------SKPQNLEILEGEKAEFVCSISK 12577
Query: 522 DPRVTIRYIWEKDGATLGT-ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
+ + W++D TL + + + I + L + D+GTY V G
Sbjct: 12578 E---SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARA 12630
Query: 581 SAHLRV 586
+AHL V
Sbjct: 12631 AAHLTV 12636
Score = 77.4 bits (189), Expect = 1e-13
Identities = 101/443 (22%), Positives = 159/443 (35%), Gaps = 77/443 (17%)
Query: 118 GEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTV 174
G K+ +V GE+ + I+ +P P VTW+R+ +I S IT ++ L+I
Sbjct: 948 GLKNVTVIEGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAF 1006
Query: 175 APDAGRYYVQAVNDKNGDNKT-------------------------------SQPITLT- 202
A D+GR+ AVN+ + + S+ + +T
Sbjct: 1007 AEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1066
Query: 203 ---VENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
E GP +P AP I P +V G S V C P K H+ WKK GV L+
Sbjct: 1067 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS-VVFGCQVGGNP--KPHVYWKKSGVPLT 1123
Query: 260 GGIS---DHNR-----RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQF- 310
G +N+ +L I DAG Y V+R+ + A S+LE +
Sbjct: 1124 TGYRYKVSYNKQTGECKLVISMTFADDAGEY--TIVVRNKHGET---SASASLLEEADYE 1178
Query: 311 -VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISG 369
+ + ++ + + + + G P + + E E+ ++ + +
Sbjct: 1179 LLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRT 1238
Query: 370 LVPDDTGMFQCFARNAAGEVQ---------------TSTYLAVTSIAPNITRGPLDS--- 411
V D F E++ +AV DS
Sbjct: 1239 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1298
Query: 412 --TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
+++GM V C+ SG P P I W K + + G F SL I D
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358
Query: 470 AGTYTCLATNSRGVDEASADLVV 492
G YT A+N +G S L V
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYV 1381
Score = 77.0 bits (188), Expect = 2e-13
Identities = 71/269 (26%), Positives = 105/269 (39%), Gaps = 58/269 (21%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-- 364
PP V + E E V + C G P P++TWY++ ++E F+ G
Sbjct: 942 PPTLVSGLKNVTVIEGESVT-LECHISGYPSPTVTWYRED--YQIESSIDFQITFQSGIA 998
Query: 365 -LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-------------------------- 397
L I +D+G F C A N AG V TS YLAV
Sbjct: 999 RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1058
Query: 398 --------TSI-----------APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKG 438
TS+ AP P+ +++G SVV C+ G P+P + W+K
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1118
Query: 439 ERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWART 496
L +G + ++G L+IS T DAG YT + N G ASA L+ A
Sbjct: 1119 GVPLTTGYRYKVSYNK-QTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177
Query: 497 RITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ Q + + + + V +P+V
Sbjct: 1178 ELLMKSQQEMLYQ----TQVTAFVQEPKV 1202
Score = 69.3 bits (168), Expect = 4e-11
Identities = 134/549 (24%), Positives = 214/549 (38%), Gaps = 78/549 (14%)
Query: 897 PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS-WEEYNRTNTRVTHYLPNVTLEYR 954
P G + +L S +SW+ P + G +T Y + E ++ +VT R
Sbjct: 30726 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTT-CR 30784
Query: 955 VTGLTALTTYTIEVAAMTSKGQG---QVSASTISSGVPPELPGPPTNLGISNIGPRSVTL 1011
+ LT Y V+A + G +VS+ I P E PG P I+ + S +
Sbjct: 30785 IVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS-PFEKPGAPGKPTITAVTKDSCVV 30843
Query: 1012 QFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
++P DG I + +E + + +W+ + + E V +L Y FR
Sbjct: 30844 AWKPPASDGGAKIRNYYLEKREK---KQNKWISV--TTEEIRETVFSVKNLIEGLEYEFR 30898
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAP------ANVSLRTASETSLWLRWM--PLPE 1122
++ N+ G S S+ S I P AP N+++R S +L + P P
Sbjct: 30899 VKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 30958
Query: 1123 ME-YNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAI 1181
++ Y E + +KY + G ++ + D T+ QV+A N
Sbjct: 30959 VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATV----------YQVRATNQG 31008
Query: 1182 GS--GPWSQTVVGRTRESVPSS--GPTNVSALATTSSSMLVRWSEVPEA----------- 1226
GS G S V + +P + G V AL S+ + +S P+
Sbjct: 31009 GSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLI 31068
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
D NG Y+V+ + LV N + G YV V A R G
Sbjct: 31069 DNNG---HYQVIVTRSFTS------LVFPNG---VERKDAGFYV-----VCAKNRFGIDQ 31111
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+ +E + DVP PP G+ +V SV L W PA+ G +IT+ + A
Sbjct: 31112 KT----VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG----SKITNYIVEKCAT 31163
Query: 1347 TATVEVLAPSARQ--YTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPS 1404
TA + AR+ YT L ++ Y FR+ A+ + G + +E T K D+ +
Sbjct: 31164 TAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK----T 31219
Query: 1405 RPMVQQEDV 1413
R M E+V
Sbjct: 31220 RAMNYDEEV 31228
Score = 67.8 bits (164), Expect = 1e-10
Identities = 85/414 (20%), Positives = 173/414 (41%), Gaps = 46/414 (11%)
Query: 16 RAARAQDDVSPYFKTEPVRTQVHL-EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY 74
+ ++A ++V + + + TQ+ + EG RLVL G+ + KW+ N ELT S EY
Sbjct: 33027 KTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA--TDVKWVLNGVELTN-SEEY 33083
Query: 75 RYMITSLDRT---------HAGFYRCIVRNRMGALLQRQTEV----QVAYMGSFEEGEKH 121
RY ++ D+T G CI + + G +++ Q ++ +++ +F +
Sbjct: 33084 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEG-IVKCQYDLTLSKELSDAPAFISQPRS 33142
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDA 178
Q+++ G+ + I+ P P++ WF++ I SS ++I+ +L I + D+
Sbjct: 33143 QNINEGQNVLFTC-EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 33201
Query: 179 GRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECV 238
G+Y ++A N + + T+ + L + +P ++ +TS+ S +++
Sbjct: 33202 GKYTIKAKNFRGQCSATASLMVLPLVE-----EPSREVVLRTSGDTSLQGSFSSQSVQMS 33256
Query: 239 ANARPL-------IKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSS 291
A+ + + + +S + + + S G + S+
Sbjct: 33257 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESST 33316
Query: 292 S--VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S + + +RG PP+ P I+ + KV+ + C G P P +TW +
Sbjct: 33317 SKMLKAGIRGI------PPKIEALPS-DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 33369
Query: 350 EVEKLTRFRQRNDGGLQ---ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI 400
++ RF N L I + D G++ N G + + + SI
Sbjct: 33370 HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423
Score = 65.9 bits (159), Expect = 4e-10
Identities = 107/426 (25%), Positives = 171/426 (40%), Gaps = 45/426 (10%)
Query: 283 ECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEP-ERHITAEMEKVVDIPCQA--KGVPPPS 339
E EA + S P+ + LS+ +P P + H+T K + I + K P
Sbjct: 14261 ENEAGVGHPSEPTEI----LSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 14316
Query: 340 ITWYKDAAVVEVEKLTRFRQRNDGGLQIS---GLVPDDTGMFQCFARNAAG-----EVQT 391
I ++ + V EK R R L+ G+VPD + + A NA G E+
Sbjct: 14317 IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 14376
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLP 450
+ P I D VI+G + + P P ++W K G+ + AS + +
Sbjct: 14377 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 14436
Query: 451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKG 510
S L + + +DAG YT N G AS ++ V + P +D
Sbjct: 14437 N--DHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIG---LPGPCKDIKASDI 14491
Query: 511 TQASMVCGVTHDP------RVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDI 564
T++S C +T +P + Y+ E+ A G ++ + +G +S T I
Sbjct: 14492 TKSS--CKLTWEPPEFDGGTPILHYVLERREA--GRRTYIPVM---SGENKLSWTVKDLI 14544
Query: 565 --GTYTCRVISA----GGNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
G Y RV + GG + + Q P P P + A+ +TW P
Sbjct: 14545 PNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPL 14604
Query: 616 FDGNSPLIRYILE-MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S ++ YI+E +++ W + P T T KGL + YQFR+ A N G
Sbjct: 14605 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILT-YTAKGLEEGKEYQFRVRAENAAGIS 14663
Query: 675 QFSKDT 680
+ S+ T
Sbjct: 14664 EPSRAT 14669
Score = 65.9 bits (159), Expect = 4e-10
Identities = 75/363 (20%), Positives = 146/363 (40%), Gaps = 33/363 (9%)
Query: 251 WKKDGVLLSG------GISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSV 304
W +GV L+ G+S ++ LTI + D G C S + +V+ Y
Sbjct: 33070 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI----SKTKEGIVKCQYDLT 33125
Query: 305 L-----EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFR 358
L + P F+ +P E + V+ C+ G P P I W+K+ + + ++ R
Sbjct: 33126 LSKELSDAPAFISQPRSQNINEGQNVL-FTCEISGEPSPEIEWFKNNLPISISSNVSISR 33184
Query: 359 QRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL----DSTVI 414
RN L+I D+G + A+N G+ + L V + +R + T +
Sbjct: 33185 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 33244
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
G + + S + + A ++ AS ++ +F + + S+ + + +
Sbjct: 33245 QGSFSSQSVQMSASKQEA-SFSSFSSSSASSMTEM-KFASMSAQSMSSMQESFVEMSSSS 33302
Query: 475 CLATNSRGVDEASADLVVWARTRITKP-----PQDQSVIKGTQASMVCGVTHDPRVTIRY 529
+ ++ E+S ++ A R P P D S+ +G ++ C T +P T
Sbjct: 33303 FMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEP--TPEV 33360
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W G + ++ R ++ +L I D G YT + + G+DS + ++ +
Sbjct: 33361 TWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Query: 587 RQL 589
R +
Sbjct: 33421 RSI 33423
Score = 64.7 bits (156), Expect = 9e-10
Identities = 118/468 (25%), Positives = 185/468 (39%), Gaps = 61/468 (13%)
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN----TLVILSTVAPD 177
Q+V G A R R+ P P+ W+++G KI S RI LVI A D
Sbjct: 2087 QTVGQGSDAHFRV-RVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAED 2145
Query: 178 AGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSE--VTL 235
+ V+A+N +TS L V+ I + VVA + T
Sbjct: 2146 SASIMVKAINIA---GETSSHAFLLVQ--------AKQLITFTQELQDVVAKEKDTMATF 2194
Query: 236 ECVANARPLIKLHIIWKKDGVLLSGG--ISDHNRR----LTIPNPTGSDAGYYECEAVLR 289
EC + P +K + W KDG+ + G H+ R L+I SDA Y C V
Sbjct: 2195 EC-ETSEPFVK--VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2251
Query: 290 ---SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY-KD 345
++ +V GA + ++ Q ++ PE + + E+E +V P +G WY D
Sbjct: 2252 ENVKTTAKLIVEGAVVEFVKELQDIEVPESY-SGELECIVS-PENIEG------KWYHND 2303
Query: 346 AAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ K T +R L + + +D G + +T+ L + I
Sbjct: 2304 VELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKLKMKPRPIAIL 2359
Query: 406 RGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
+G D V +G V L + S + + G+ + S V + +S LLI
Sbjct: 2360 QGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI--VIDKQSHMLLIEDM 2417
Query: 466 HISDAGTYTC------LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGV 519
DAG Y+ L+T+ R V S D++ P +D +VI+GT+A + C V
Sbjct: 2418 TKEDAGNYSFTIPALGLSTSGR-VSVYSVDVIT--------PLKDVNVIEGTKAVLECKV 2468
Query: 520 THDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
+ P VT + D + I L I++T + D G Y
Sbjct: 2469 S-VPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2515
Score = 64.7 bits (156), Expect = 9e-10
Identities = 89/345 (25%), Positives = 132/345 (38%), Gaps = 38/345 (11%)
Query: 268 RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVD 327
RL IP+ SDAG Y A S+ V G + + + +K+ E + + VV+
Sbjct: 3113 RLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRI----RSIKK-EVQVIEKQRAVVE 3167
Query: 328 IPCQAKGVPPPSITWYKDAAVVEVEKLTRFR---QRNDGGLQISGLVPDDTGMFQCFARN 384
V WYKD + + R + +R + IS D G +
Sbjct: 3168 FEVNEDDV---DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF---- 3220
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLACETSGAPRPAITWQKGERILA 443
AG ++S L V + P L TV G SG P+P I+W K E++L+
Sbjct: 3221 VAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLS 3280
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA--------- 494
+G + + +LL+ DA YTC A N GV SA L V
Sbjct: 3281 TG-FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3339
Query: 495 ----RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW-EKDGATLGTESHPRIRLD 549
I P QD +G A C V+ ++ W KD + + +
Sbjct: 3340 MPVYPPAIITPLQDTVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIKPSRFFRMTQFE 3396
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE 594
L I++ + D GTYT +A G S +A+L + APE
Sbjct: 3397 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL----EAPE 3437
Score = 64.3 bits (155), Expect = 1e-09
Identities = 103/471 (21%), Positives = 164/471 (34%), Gaps = 106/471 (22%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQ 197
P P VTW R G+ + S+R +T ++T I S A D G Y V +N + K
Sbjct: 32588 PVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVV---ENSEGKQEA 32644
Query: 198 PITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVL 257
TLT++ A + PP+ V + P +K K
Sbjct: 32645 EFTLTIQK----ARVTEKAVTSPPR---------------VKSPEPRVKSPEAVKSP--- 32682
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA-YLSVLEPPQFVKEPER 316
+R+ P P+ +AV + + P+ +L V PP+ + +
Sbjct: 32683 ---------KRVKSPEPSHP-------KAVSPTETKPTPTEKVQHLPVSAPPKITQFLKA 32726
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQISGLVPDD 374
+ E+ K+ + ++ + +TWYKD ++ +F DG L+I+ L D
Sbjct: 32727 EASKEIAKLTCV-VESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESD 32785
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G + CE SG
Sbjct: 32786 QGEY-------------------------------------------VCEISG------- 32795
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 494
+G + F + IS T SD T T E A + +
Sbjct: 32796 --EGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT---EPKAPEPISS 32850
Query: 495 RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS- 553
+ I QD +V + A T +PR T IW KDG + ++ D+ G
Sbjct: 32851 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTA--IWTKDGKAITQGGKYKLSEDKGGFF 32908
Query: 554 LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVE 604
L I +T + D G YTC V ++ G+ S S L ++ + V+T T E
Sbjct: 32909 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 32959
Score = 62.4 bits (150), Expect = 5e-09
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 8/165 (4%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQ 390
G P P ++W++D V+ L + G L I + ++G + A N +G+
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQAT 90
Query: 391 TSTYLAVTS--IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSV 447
++ L V + PN + TV G V L +G P P + + + G I +S
Sbjct: 91 STAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDF 150
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
Q+ + L S LLI+ + D+GTY+ ATNS G ++A+L+V
Sbjct: 151 QISQEGDLYS--LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 62.0 bits (149), Expect = 6e-09
Identities = 51/212 (24%), Positives = 104/212 (49%), Gaps = 13/212 (6%)
Query: 397 VTSIAPNITRGPLDSTVI-DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPL 455
+T+ AP T+ PL S V+ +G + SG P P ++W + +++++ ++ + +
Sbjct: 1 MTTQAPTFTQ-PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS 59
Query: 456 ESGSLLISPTHI-SDAGTYTCLATNSRGVDEASADLVVWART---RITKPPQDQSVIKGT 511
+ + L P +++G Y+ ATN G ++A+L+V A T + Q +V +G+
Sbjct: 60 DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGS 119
Query: 512 QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH---ISQTWSGDIGTYT 568
Q + VT P +++ +DGA + +S ++ + G L+ I++ + D GTY+
Sbjct: 120 QVRLQVRVTGIPTPVVKFY--RDGAEI--QSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 569 CRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
++ G + +A L V+ P T+
Sbjct: 176 VNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Score = 62.0 bits (149), Expect = 6e-09
Identities = 50/193 (25%), Positives = 85/193 (44%), Gaps = 13/193 (6%)
Query: 214 APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG--------ISDH 265
APT P ++ V+ G S T E + P+ + + W +DG ++S SD
Sbjct: 5 APTFTQPLQSVVVLEG-STATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDG 61
Query: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
+LTIP T +++G Y +A S S + PP FV+ + +T
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-SMTVRQGSQ 120
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARN 384
V + + G+P P + +Y+D A ++ + Q D L I+ P+D+G + A N
Sbjct: 121 VRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 385 AAGEVQTSTYLAV 397
+ G ++ L V
Sbjct: 181 SVGRATSTAELLV 193
Score = 61.6 bits (148), Expect = 8e-09
Identities = 73/294 (24%), Positives = 108/294 (36%), Gaps = 64/294 (21%)
Query: 343 YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA- 401
YK A VEV+K + G+ I+G + F+ A +T+ A I
Sbjct: 890 YKSEAGVEVKK--------EVGVSITGTTVREE-RFEVLHGREAKVTETARVPAPVEIPV 940
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P + G + TVI+G SV L C SG P P +TW + + + S S+
Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIES-SIDFQITFQSGIAR 999
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADL----------------------------- 490
L+I D+G +TC A N G S L
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059
Query: 491 --VVWARTRITK---------------PPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
VV T +T+ P Q +++G C V +P+ + W+K
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV--YWKK 1117
Query: 534 DGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
G L T ++ ++ L IS T++ D G YT V + G S SA L
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 58.9 bits (141), Expect = 5e-08
Identities = 73/277 (26%), Positives = 111/277 (40%), Gaps = 21/277 (7%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSI--TWYKDAAVVEVEKLTRF-RQRNDG 363
P +FVKE + I E E V V P + TW KD + + RF D
Sbjct: 11114 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 11173
Query: 364 GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLA 422
L I + D G + C R E ++ L V + + + TV+ G + L+
Sbjct: 11174 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLS 11233
Query: 423 CETSGAPRPAITWQKGERILASGSVQLP-RFTPLESG---SLLISPTHISDAGTYTCLAT 478
CE + + W+K +I+ V+ P R P G +L I+ +DAGTYT
Sbjct: 11234 CELN--KERDVVWRKDGKIV----VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 11287
Query: 479 NSRGVDEASADLVVWA-RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
N+ ++ +S VV R + KP +DQ V A C + D T W K
Sbjct: 11288 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKD---TPNIKWFKGYDE 11344
Query: 538 LGTESHPRIRLDRNGS---LHISQTWSGDIGTYTCRV 571
+ E + + + R+G+ L I DI Y +
Sbjct: 11345 IPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 11381
Score = 58.5 bits (140), Expect = 7e-08
Identities = 119/615 (19%), Positives = 209/615 (33%), Gaps = 95/615 (15%)
Query: 22 DDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSL 81
+ +PYF T+PV Q +EG +V C G+ W + LT YRY ++
Sbjct: 1078 EPAAPYFITKPV-VQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTT---GYRYKVSYN 1133
Query: 82 DRT-------------HAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGE 128
+T AG Y +VRN+ G + ++ A + ++
Sbjct: 1134 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQV 1193
Query: 129 AAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVND 188
A ++ P++ V + + I + V++ T D +++ + +
Sbjct: 1194 TAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQ-EFHISSFEE 1252
Query: 189 KNGDNKTSQPITLTVENVG------------GPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
+ + I T+E + ++ + KN ++ G VT
Sbjct: 1253 RLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMG-VTFH 1311
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-------ISDHNRRLTIPNPTGSDAGYYECEAVLR 289
C + PL K I W KDG + G + D L IP D G Y A
Sbjct: 1312 CKMSGYPLPK--IAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA--- 1366
Query: 290 SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S ++G + C K P+ +
Sbjct: 1367 -----SNIKGNAI---------------------------CSGKLYVEPAAPLGAPTYIP 1394
Query: 350 EVEKLTRFRQRNDGGLQISGLVPDDTGMFQCF---ARNAAGEVQTSTYLAVTSIA----- 401
+E ++R R + + S + M AR + + L T +
Sbjct: 1395 TLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERL 1454
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P P+ ++G + + G P P W + + + + S
Sbjct: 1455 YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQS 1514
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQAS 514
L+I P SD+G +T +A N G S L V A KP ++ ++ +G++
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1574
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD---RNGSLHISQTWSGDIGTYTCRV 571
M T +P I +W K+ + +P+IR++ +L I T S D YT
Sbjct: 1575 MKVRATGNPNPDI--VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1632
Query: 572 ISAGGNDSRSAHLRV 586
I+ G D+ + V
Sbjct: 1633 INKAGRDTTRCKVNV 1647
Score = 58.5 bits (140), Expect = 7e-08
Identities = 63/252 (25%), Positives = 95/252 (37%), Gaps = 21/252 (8%)
Query: 262 ISDHNRRLTIPNPTGSDAGYYEC---------EAVLRSSSVPSVVRGAYLSVLEPPQFVK 312
+ D R + N G D+ Y E + R + R + +LE P
Sbjct: 31634 LDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFT 31693
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRNDGGLQ---IS 368
P + TA + + V P P +TWYK ++ + ++ +D GL I+
Sbjct: 31694 LPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTIN 31753
Query: 369 GLVPDDTGMFQCFARNAAGEVQTSTYLAVT--------SIAPNITRGPLDSTVIDGMSVV 420
+ DD + ARN GE L VT ++ P R ++ +G SV
Sbjct: 31754 SVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVC 31813
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
SG P P + W+K + L+ G L+ +L I T D G Y ATN+
Sbjct: 31814 FEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT 31873
Query: 481 RGVDEASADLVV 492
G A L V
Sbjct: 31874 AGSTSCQAHLQV 31885
Score = 57.8 bits (138), Expect = 1e-07
Identities = 84/361 (23%), Positives = 124/361 (34%), Gaps = 62/361 (17%)
Query: 279 AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPP 338
A C +RS SV + S+ P V H E V C+ +
Sbjct: 31540 AARISCGGAIRSQKGVSVAKVKVASIEIGP--VSGQIMHAVGEEGGHVKYVCKIENYDQS 31597
Query: 339 S-ITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTY 394
+ +TWY V ++E ++ + G L + + D G ++C N GE +
Sbjct: 31598 TQVTWY--FGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAE 31655
Query: 395 LAVTSIA---------------------------PNITRGPLDSTVIDGMSVVLACETSG 427
L V + P T + T G +V +
Sbjct: 31656 LFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITV 31715
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDE 485
P P +TW K + + G + G L I+ D YT +A N G D
Sbjct: 31716 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS 31775
Query: 486 ASADLVVWARTRITKPPQDQSV---IKGTQASMVCG----------VTHDPRVTIRYIWE 532
A L V + PP D ++ K A+ C V+ P T++ WE
Sbjct: 31776 CKAKLTV----TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WE 31829
Query: 533 KDGATLGTESHPRIRLDRNG----SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
KDG L P I + G +LHI T D G Y + G+ S AHL+V +
Sbjct: 31830 KDGQPLSLG--PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVER 31887
Query: 589 L 589
L
Sbjct: 31888 L 31888
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Query: 388 EVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSV 447
E +++T T++A I P TV +G S +C+T G P P +TW + ++L++ +
Sbjct: 32547 EEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSAR 32606
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW----ARTRITKPPQ 503
T +S + IS SD G Y+ + NS G EA L + +T PP+
Sbjct: 32607 HQVTTTKYKS-TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPR 32665
Query: 504 DQS 506
+S
Sbjct: 32666 VKS 32668
Score = 55.8 bits (133), Expect = 4e-07
Identities = 90/391 (23%), Positives = 145/391 (37%), Gaps = 54/391 (13%)
Query: 56 LEFKWLHNN--RELTKF--SLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY 111
L+ WL R TK +L++R +L + R G ++ Q V VA
Sbjct: 31500 LQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAK 31559
Query: 112 M--GSFEEGEKHQSVSH--GEAA--VIRAPRIASFPQP-QVTWFRDGRKIPPSSRIAITL 164
+ S E G + H GE V +I ++ Q QVTW+ R++ S + IT
Sbjct: 31560 VKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 31619
Query: 165 ENTLVIL---STVAPDAGRYYVQAVNDKNGDNKTSQPIT------------LTVENVGGP 209
E+ + IL D G Y + VND D+ ++ T++ +
Sbjct: 31620 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 31679
Query: 210 ADPI-----APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISD 264
D + P +P N + G V P + H+ W K G + G +D
Sbjct: 31680 TDTMRLLERPPEFTLPLYNKTAYVG-ENVRFGVTITVHP--EPHVTWYKSGQKIKPGDND 31736
Query: 265 HN---------RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP---QFVK 312
+LTI + T D Y V R+ + L PP ++
Sbjct: 31737 KKYTFESDKGLYQLTINSVTTDDDAEY--TVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 31794
Query: 313 EPERHITAEME----KVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRND-GGLQ 366
+ + A E + V + G+PPP++ W KD + + + + D L
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
I +P+DTG ++ A N AG +L V
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 55.5 bits (132), Expect = 6e-07
Identities = 129/618 (20%), Positives = 223/618 (36%), Gaps = 82/618 (13%)
Query: 24 VSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFS---LEYR----- 75
+ P F T EGN L GS P+ W NN E+ S + ++
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 8306
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEV--QVAYMGSFEEGEKHQSVSHGEAAVIR 133
+ AG Y C V N G+ L + V + F++ +VS GE +
Sbjct: 8307 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLS 8366
Query: 134 APRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVIL---STVAPDAGRYYVQAVNDKN 190
S P ++ W + GR+I PS R + + + +L D+G Y +A N
Sbjct: 8367 CHVQGSEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASN-VA 8424
Query: 191 GDNKTSQPITLTVENVGGPADPIAPT-----IIIPPKNTSVVAGTSEVTLECVANARPLI 245
G + T +T+ + PA A + P++ VV T+ T P+
Sbjct: 8425 GSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTT-ATFIAKVGGDPIP 8483
Query: 246 KLHIIWKKDGVLLSGG-ISDHNR----RLTIPNPTGSDAGYYECEAVLRSSSVPS----- 295
+ K L GG + H + +L I + T +D+G Y C A + S
Sbjct: 8484 NVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQ 8543
Query: 296 --------VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAA 347
+ G ++L+ +K+ A E+ +DI K V P Y
Sbjct: 8544 VDERKKQEKIEGDLRAMLKKTPILKK-----GAGEEEEIDIMELLKNVDPKEYEKY---- 8594
Query: 348 VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQC--FARNAAGEVQTSTYLA-----VTSI 400
+ +T FR + ++T + R+ E + ++ ++
Sbjct: 8595 -ARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQT 8653
Query: 401 AP-NITRGPLDSTVIDGMSVVLACETS-GAPRPAITWQKG-ERILASGSVQLPRFTPLES 457
P + + + TV+ V + P ++W KG E++ S ++ +
Sbjct: 8654 EPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEIS--IDGDR 8711
Query: 458 GSLLISPTHISDAGTYTCLATNSRGVDEASADLVV----WARTRITKPPQDQSVIKGTQA 513
+L + + D G Y + G ASA L V W R QD ++ +G
Sbjct: 8712 HTLRVKNCQLKDQGNYRLVC----GPHIASAKLTVIEPAWERHL-----QDVTLKEGQTC 8762
Query: 514 SMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVI 572
+M C + ++ W ++G L + + ++ L I+ + D G YTC+
Sbjct: 8763 TMTCQFSVP---NVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYE 8819
Query: 573 SAGGNDSRSAHLRVRQLP 590
SA LR+ P
Sbjct: 8820 DL----ETSAELRIEAEP 8833
Score = 55.5 bits (132), Expect = 6e-07
Identities = 62/224 (27%), Positives = 93/224 (41%), Gaps = 25/224 (11%)
Query: 1721 QAAPSAPSS-VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVS-KIVTVD 1777
Q P P+ + L S +SW+ P G + Y V E C +G ++V+
Sbjct: 30720 QDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNY--VVEKCEAKEGAEWQLVSSA 30777
Query: 1778 VKGNSPLWLKVKDLAEGVTYRFRIRAK-TFTYGPEIEAN---VTTGPGE--GAPGPPGVP 1831
+ S ++ +L E Y FR+ A+ TF +E + + P E GAPG P +
Sbjct: 30778 I---SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 30834
Query: 1832 IIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILK 1891
+ + S +A + D G I Y +E R + W I +E+ FS+ L
Sbjct: 30835 AVTKDSCVVAWKPPASDGG-AKIRNYYLEKREKKQNKW---ISVTTEEIRETVFSVKNLI 30890
Query: 1892 PGVSYDFRVIAVNDYG------FGTPSSPSQSVPAQKANPFYEE 1929
G+ Y+FRV N G P +P VP Q A F EE
Sbjct: 30891 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ-APHFKEE 30933
Score = 55.1 bits (131), Expect = 7e-07
Identities = 128/600 (21%), Positives = 208/600 (34%), Gaps = 102/600 (17%)
Query: 23 DVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---KFSLEYRYM-- 77
+ PYF T + + +E + + L C P+ KW + E+ K+S++ +
Sbjct: 11660 EADPYF-TVKLHDKTAVEKDEITLKCEVSKDVPV--KWFKDGEEIVPSPKYSIKADGLRR 11716
Query: 78 ---ITSLDRTHAGFYRCIV---RNRMGALLQRQ----------TEVQVAYMGSFEEGEKH 121
I D G Y C + + ++ + EV V FE
Sbjct: 11717 ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSE 11776
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY 181
V HG+ + P AS P DG+K + L++ + G
Sbjct: 11777 PDV-HGQWKLKGQPLTAS---PDCEIIEDGKK------------HILILHNCQLGMTGEV 11820
Query: 182 YVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANA 241
QA N K+ N L V+ + P I I P + V E EC +
Sbjct: 11821 SFQAANAKSAAN-------LKVKEL--------PLIFITPLSDVKVFEKDEAKFECEVSR 11865
Query: 242 RPLIKLHIIWKKDGVLLSGG-----ISDHNRR-LTIPNPTGSDAGYYECEAVLRSSSVPS 295
P W K ++G I D + + I + D Y EA + +S
Sbjct: 11866 EPKT---FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKL 11922
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKL 354
++ G L L P + V E+ V + + + W+K D + +
Sbjct: 11923 IIEGIRLKFLTPLKDVTAKEKE-----SAVFTVELSHDNI---RVKWFKNDQRLHTTRSV 11974
Query: 355 TRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI 414
+ + + L DDT + A + E + L V P T D T +
Sbjct: 11975 SMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAK----LTVLEGDPYFTGKLQDYTGV 12030
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
+ V+L CE S A P ++ G+ I S + + + L++ SD G YT
Sbjct: 12031 EKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIK--ADGKKRMLILKKALKSDIGQYT 12088
Query: 475 CLATNSRGVDEASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
C G D+ S L + R ++ +P V++ A ++ D I W+
Sbjct: 12089 C----DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISED---DIHANWKL 12141
Query: 534 DGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG------NDSRSAHLRVR 587
G L P + G +H + + CR+ GG N SAHLRV+
Sbjct: 12142 KGEAL--LQTPDCEIKEEGKIH-------SLVLHNCRLDQTGGVDFQAANVKSSAHLRVK 12192
Score = 54.7 bits (130), Expect = 1e-06
Identities = 91/439 (20%), Positives = 152/439 (34%), Gaps = 53/439 (12%)
Query: 92 IVRNRMGALLQRQTEVQVAY--------MGSFEEGEKHQSVSHGEAAVIRAPRIASFPQP 143
I++ + LL+ E ++A F+ K+ + G +++ +P P
Sbjct: 1262 IIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHC-KMSGYPLP 1320
Query: 144 QVTWFRDGRKIPPSSRIAITL----ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPI 199
++ W++DG++I R + +L I + D G Y A N K + +
Sbjct: 1321 KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK-- 1378
Query: 200 TLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
L VE PA P+ IP TLE V+ R L + + + +S
Sbjct: 1379 -LYVE----PAAPLGAPTYIP-------------TLEPVSRIRSLSPRSV--SRSPIRMS 1418
Query: 260 GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHIT 319
R +P L + + R L P FV +P
Sbjct: 1419 PARMSPARM----SPARMSPARMSPGRRLEETDESQLER------LYKPVFVLKPVSFKC 1468
Query: 320 AEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGLVPDDTGM 377
E + + G P P W+ D + + + + DG L I P D+G
Sbjct: 1469 LEGQ-TARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGE 1527
Query: 378 FQCFARNAAGEVQTSTYLAVTSIA----PNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
+ A+N AG S L V ++ P + + +G + + +G P P I
Sbjct: 1528 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1587
Query: 434 TWQKGERILASGSVQLPRFTPLES-GSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
W K I+ R + +L I T D+ YT A N G D + V
Sbjct: 1588 VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Query: 493 WARTRITKPPQDQSVIKGT 511
+P + + +GT
Sbjct: 1648 EVEFAEPEPERKLIIPRGT 1666
Score = 53.5 bits (127), Expect = 2e-06
Identities = 85/398 (21%), Positives = 146/398 (36%), Gaps = 47/398 (11%)
Query: 221 PKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG-----ISDHNRRLTIPNPT 275
P V + ECV + ++IW K ++ I+D + + + N +
Sbjct: 11491 PLKDVTVPERRQARFECVLTR----EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 11546
Query: 276 G-SDAGYYECEAVLRSSSVPSVVRGAYLSVLEP--PQFVKEPERHITAEMEKVVDIPCQA 332
D G Y E + +S V G L + P Q VKE E C+
Sbjct: 11547 QFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGE---------TATFVCEL 11597
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARNAAGEVQT 391
+ W+K+ A + + L++ + DD + + E+ +
Sbjct: 11598 SH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----ELSS 11652
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPR 451
+ L V P T D T ++ + L CE S P ++ GE I+ S P+
Sbjct: 11653 TAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVKWFKDGEEIVPS-----PK 11706
Query: 452 FTPLESG---SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR-TRITKPPQDQSV 507
++ G L I + D G Y C G D+ A++ V AR ++ KP V
Sbjct: 11707 YSIKADGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARLIKVEKPLYGVEV 11762
Query: 508 IKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
G A ++ + W+ G L + P + +G HI + +G
Sbjct: 11763 FVGETAHFEIELSEP---DVHGQWKLKGQPL--TASPDCEIIEDGKKHILILHNCQLG-M 11816
Query: 568 TCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
T V N +A+L+V++LP P++ + E+
Sbjct: 11817 TGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEK 11854
Score = 53.1 bits (126), Expect = 3e-06
Identities = 97/442 (21%), Positives = 163/442 (36%), Gaps = 51/442 (11%)
Query: 145 VTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITL 201
V WF+DG++I PS I + L++ + D G+Y G +KTS + +
Sbjct: 12048 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC-----GTDKTSGKLDI 12102
Query: 202 TVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLL--- 258
+ + P + T +E++ + +H WK G L
Sbjct: 12103 EDREI----KLVRPLHSVEVMETETARFETEISED---------DIHANWKLKGEALLQT 12149
Query: 259 -SGGISDHNR--RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPE 315
I + + L + N G + +A SS V+ + +L P + V
Sbjct: 12150 PDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT--- 12206
Query: 316 RHITAEMEKVVDIPCQAKGVPPPSITWY-KDAAVVEVEKLTRFRQRNDGGLQISGLVPDD 374
+TA D + +P + WY K + +K+ + L + + +D
Sbjct: 12207 --VTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 12261
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G Q A+ + +T L V T+ D TV +G + VL CE S
Sbjct: 12262 AGEVQLTAK----DFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKW 12317
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADL-VVW 493
++ G IL S ++ + L+I D TYTC A + + S +L VV
Sbjct: 12318 FKNGTEILKSKKYEIVADGRVR--KLVIHDCTPEDIKTYTCDAKDFK----TSCNLNVVP 12371
Query: 494 ARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT-ESHPRIRLDRNG 552
+P D V + A C ++ R + W KDGA + + + I
Sbjct: 12372 PHVEFLRPLTDLQVREKEMARFECELS---RENAKVKWFKDGAEIKKGKKYDIISKGAVR 12428
Query: 553 SLHISQTWSGDIGTYTCRVISA 574
L I++ D Y+C V +A
Sbjct: 12429 ILVINKCLLDDEAEYSCEVRTA 12450
Score = 50.8 bits (120), Expect = 1e-05
Identities = 68/294 (23%), Positives = 106/294 (36%), Gaps = 43/294 (14%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTR--FRQRNDGGLQISGLVPDDTGMFQCFAR 383
V C+ G P P I WYKD ++ + + F Q L+I ++P+D G++ FA
Sbjct: 1308 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1367
Query: 384 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 443
N G S L V AP GAP T + RI +
Sbjct: 1368 NIKGNAICSGKLYVEPAAP-----------------------LGAPTYIPTLEPVSRIRS 1404
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP-- 501
+ R +P+ +SP +S A + R ++E + R+ KP
Sbjct: 1405 LSPRSVSR-SPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQL----ERLYKPVF 1459
Query: 502 ---PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG--SLHI 556
P ++G A V P W DG + + ++ + +G SL I
Sbjct: 1460 VLKPVSFKCLEGQTARFDLKVVGRPMP--ETFWFHDGQQIVNDYTHKVVIKEDGTQSLII 1517
Query: 557 SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINL 610
D G +T + G S S L V A EH V + + + +N+
Sbjct: 1518 VPATPSDSGEWTVVAQNRAGRSSISVILTV----EAVEHQVKPMFVEKLKNVNI 1567
Score = 50.4 bits (119), Expect = 2e-05
Identities = 104/471 (22%), Positives = 175/471 (37%), Gaps = 66/471 (14%)
Query: 113 GSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLV 169
G+ + Q+V+ + AV + P + W RDG+ +P ++ I + L+
Sbjct: 2620 GAISKPLTDQTVAESQEAVFECE--VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLI 2677
Query: 170 ILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAG 229
I +T D G Y + K L VE V I T+ KN +V
Sbjct: 2678 IAATKLDDIGEYTYKVATSKTS-------AKLKVEAV-----KIKKTL----KNLTVT-- 2719
Query: 230 TSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLR 289
++ + V P +K + W K+GV+L + N + I S G +
Sbjct: 2720 ETQDAVFTVELTHPNVK-GVQWIKNGVVL-----ESNEKYAI-----SVKGTIYSLRIKN 2768
Query: 290 SSSVPSVVRGAYLSVL--------EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSIT 341
+ V V G L L E + +K+P + +TA V P
Sbjct: 2769 CAIVDESVYGFRLGRLGASARLHVETVKIIKKP-KDVTALENATVAFEVSVSHDTVPVKW 2827
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
++K + +K +R L + + P D G + G+++ L V ++
Sbjct: 2828 FHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTA----VVGQLECKAKLFVETL- 2882
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+IT+ + V + + CE S P++ + G I S ++ L L+
Sbjct: 2883 -HITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLH--QLI 2939
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
I T D+ YT + N D+ SA L V P S++K A +T
Sbjct: 2940 IMNTSTEDSAEYTFVCGN----DQVSATLTV-------TPIMITSMLKDINAEEKDTITF 2988
Query: 522 DPRVT---IRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYT 568
+ V I Y W K+G + + ++R + SL+I GD YT
Sbjct: 2989 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYT 3039
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/350 (24%), Positives = 134/350 (38%), Gaps = 39/350 (11%)
Query: 232 EVTLEC-VANARPLIKLHIIWKKDGVLLSGG------ISDHNRRLTIPNPTGSDAGYYEC 284
EV L+C ++ A +K W KDG + R L + SD G Y C
Sbjct: 12034 EVILQCEISKADAPVK----WFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC 12089
Query: 285 EAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV---DIPCQAKGVPPPSIT 341
+ +S + + ++ P V+ E TA E + DI K
Sbjct: 12090 DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETE-TARFETEISEDDIHANWK-------- 12140
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
K A+++ + L + D TG A N V++S +L V
Sbjct: 12141 -LKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAAN----VKSSAHLRVKPRV 12195
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+ R D TV G + CE S P + KG+++ S V +PR + + +L
Sbjct: 12196 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKV-VPR-SEGKVHTLT 12253
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVV-WARTRITKPPQDQSVIKGTQASMVCGVT 520
+ + DAG A + + A+L V TKP +DQ+V +G A + C V+
Sbjct: 12254 LRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS 12309
Query: 521 HDPRVTIRYIWEKDGA-TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTC 569
R + W K+G L ++ + + R L I DI TYTC
Sbjct: 12310 ---RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 12356
Score = 48.1 bits (113), Expect = 9e-05
Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 1850 GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G +T Y++E R +D W + EV +F + L PG Y FRV AVN+YG G
Sbjct: 18726 GGSQVTHYIVEKREADRKTWST----VTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPG 18781
Query: 1910 TPSSPSQSVPA 1920
P+ + V A
Sbjct: 18782 VPTDVPKPVLA 18792
Score = 47.8 bits (112), Expect = 1e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 1364 GLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW- 1422
G++ + + + A+ R G + L V D P PP V+ DV SV L+W
Sbjct: 31090 GVERKDAGFYVVCAKNRFGIDQKTVELDVA----DVPDPPRG--VKVSDVSRDSVNLTWT 31143
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
EP SDG S + Y ++ + RW + + + V L TSY+FRV A N
Sbjct: 31144 EPASDGGSKITNYIVEKCATTAERWLRVGQA---RETRYTVINLFGKTSYQFRVIAENKF 31200
Query: 1483 GDSEFSEESESLTT 1496
G S+ SE SE T
Sbjct: 31201 GLSKPSEPSEPTIT 31214
Score = 47.0 bits (110), Expect = 2e-04
Identities = 66/318 (20%), Positives = 120/318 (37%), Gaps = 55/318 (17%)
Query: 30 TEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSL----------EYRYMIT 79
T+P+++ V LEG+ G E W + + ++ +L + I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 80 SLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP-RIA 138
++ + ++G Y N G + A ++ QS++ + + +R R+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 139 SFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
P P V ++RDG +I S I+ E +L+I D+G Y V A N T
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATST 188
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVT----------LECVANARPLI 245
++ + E V P K T + T++++ +E +AR +
Sbjct: 189 AELLVQGEEEV-------------PAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIA 235
Query: 246 KLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVL 305
+ ++ DG +G H IP S RS + PS+ A L+
Sbjct: 236 TVEMV--IDGA--AGQQLPHKTPPRIPPKPKS-----------RSPTPPSIAAKAQLARQ 280
Query: 306 EPPQFVK---EPERHITA 320
+ P ++ P RH+ A
Sbjct: 281 QSPSPIRHSPSPVRHVRA 298
Score = 46.2 bits (108), Expect = 3e-04
Identities = 64/304 (21%), Positives = 114/304 (37%), Gaps = 32/304 (10%)
Query: 304 VLEPPQFVKEPERHITAEMEKVVDIPC--------QAKGVPPPSITWYKDAAVVEVEKLT 355
VL F + IT M +PC + P + WY + VE+++ +
Sbjct: 32362 VLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQSKPTAEVKWYHNG--VELQESS 32418
Query: 356 RFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-----TSIAPNITRG 407
+ N G L+I DD+G ++ N GE L V T+ A
Sbjct: 32419 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDE 32478
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHI 467
+ +V ++ A S +++K + AS SV+ + E+ L S H
Sbjct: 32479 EVPRSVFPELTRTEAYAVS-------SFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 32531
Query: 468 SDAGTYTCLATNSRGVDEASA--DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ A + A + ++E S + RI P+ +V +G A C +P
Sbjct: 32532 ASAEMKSA-ALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVP 32590
Query: 526 TIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
T+ W + G L T + ++ + + IS + D G Y+ V ++ G L
Sbjct: 32591 TV--TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 32648
Query: 585 RVRQ 588
+++
Sbjct: 32649 TIQK 32652
Score = 42.7 bits (99), Expect = 0.004
Identities = 102/543 (18%), Positives = 186/543 (34%), Gaps = 78/543 (14%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDN 193
+ S P +V W+ +G ++ SS+I T + TL IL D+G Y N K
Sbjct: 32397 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG--- 32453
Query: 194 KTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKK 253
+ S TL V GG A SV + V++ + K
Sbjct: 32454 EASDYATLDV--TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK---------KT 32502
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSD----AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQ 309
+ S + + ++T + S A A L S+ + +
Sbjct: 32503 SEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR 32562
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVE---KLTRFRQRNDGGLQ 366
+ +P R +T + C G P P++TW + V+ ++T + ++ +
Sbjct: 32563 ILTKP-RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKST--FE 32619
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS 426
IS + D G + N+ G+ + L + +T V +
Sbjct: 32620 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKA--RVTE-----------KAVTSPPRV 32666
Query: 427 GAPRPAITWQKGERILASGSVQLPRF--TPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
+P P R+ + +V+ P+ +P S +SPT T
Sbjct: 32667 KSPEP--------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPT------------ 32706
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHP 544
E L V A +IT+ + ++ A + C V W KDG L H
Sbjct: 32707 EKVQHLPVSAPPKITQFLKAEA--SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHF 32764
Query: 545 RIRLDRNGS--LHISQTWSGDIGTYTCRVISAGGNDS----------RSAHLRVRQLPHA 592
+ +G+ L I+ D G Y C + GG +S H +V ++
Sbjct: 32765 QFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISET 32824
Query: 593 PEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE--MSENNAPWTVLLASVDPKATSV 650
+ T + R +P ++ + + +S ++ + A+ +P+ T++
Sbjct: 32825 KKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAI 32884
Query: 651 TVK 653
K
Sbjct: 32885 WTK 32887
Score = 40.8 bits (94), Expect = 0.015
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 11/145 (7%)
Query: 77 MITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE-----KHQSVSHGEAAV 131
+IT+L + +R + N G R V + E + SV G+
Sbjct: 23189 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 23248
Query: 132 IRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVND 188
I P I+ P+P +TW +DG + ++RI +T TL I T D G+Y + N
Sbjct: 23249 IEVP-ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV 23307
Query: 189 KNGDNKTSQPITLTVENVGGPADPI 213
KT+ +T++ P P+
Sbjct: 23308 VG--QKTASIEIVTLDKPDPPKGPV 23330
Score = 40.4 bits (93), Expect = 0.019
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAG 179
++ G+ V+ A I P P+ +W + G+ I PS IT T L I DAG
Sbjct: 20389 TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAG 20448
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
Y + A N + + +TV +V GP P+ + + K T
Sbjct: 20449 EYTITATNP---FGTKVEHVKVTVLDVPGPPGPVEISNVSAEKAT 20490
Score = 40.0 bits (92), Expect = 0.025
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 20/175 (11%)
Query: 416 GMSVVLACETSGAPRPAIT-WQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAG 471
G S + C S P AIT W K S + P+ + G L I +SDAG
Sbjct: 11133 GSSAIFECLVS--PSTAITTWMKD----GSNIRESPKHRFIADGKDRKLHIIDVQLSDAG 11186
Query: 472 TYTCLATNSRGVDEASADLVV-WARTRITKPPQDQ-SVIKGTQASMVCGVTHDPRVTIRY 529
YTC+ ++A LVV R K +++ +V+KG + C + + V
Sbjct: 11187 EYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV---- 11242
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRS 581
+W KDG + E RI G +L I+ D GTYT V +A + S
Sbjct: 11243 VWRKDGKIV-VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSS 11296
Score = 39.3 bits (90), Expect = 0.043
Identities = 54/219 (24%), Positives = 84/219 (38%), Gaps = 29/219 (13%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---------KFSLEYRY 76
P F +PV + LEG G E W H+ +++ K
Sbjct: 1457 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 77 MITSLDRTHAGFYRCIVRNRMGA------LLQRQTEVQVAYMGSFEEGEKHQSVSHGEAA 130
+I + +G + + +NR G L E QV M F E K+ ++ G
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPM--FVEKLKNVNIKEGSRL 1573
Query: 131 VIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT-----LVILSTVAPDAGRYYVQA 185
++ R P P + W ++ I P I +E T L I STV+ D+ Y A
Sbjct: 1574 EMKV-RATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1632
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
+N K G + T + + VE A+P +I P+ T
Sbjct: 1633 IN-KAGRDTTRCKVNVEVEF----AEPEPERKLIIPRGT 1666
Score = 38.9 bits (89), Expect = 0.056
Identities = 39/150 (26%), Positives = 59/150 (39%), Gaps = 16/150 (10%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY-----MGSFEEGEKHQSVSH---G 127
+ +TSL+ +R +N G R+T V + + + Q H G
Sbjct: 29694 HTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAG 29753
Query: 128 EAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAI---TLENTLVILSTVAPDAGRYYVQ 184
+ P IA P P +WF G K+ S R+ + T L I T D G Y ++
Sbjct: 29754 RPVELVIP-IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 29812
Query: 185 AVNDKNGDNKTSQPI-TLTVENVGGPADPI 213
KN TS+ I + ++ G P PI
Sbjct: 29813 L---KNVTGTTSETIKVIILDKPGPPTGPI 29839
Score = 38.9 bits (89), Expect = 0.056
Identities = 58/210 (27%), Positives = 85/210 (40%), Gaps = 29/210 (13%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSR-IAITLEN-----TLVILSTVAPDAGRYYVQAVNDKN 190
I P+P VTW++ G+KI P T E+ L I S D Y V A N K
Sbjct: 31713 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARN-KY 31771
Query: 191 GDNKTSQPITLTVENVGGPAD-PIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHI 249
G++ +T+T+ P D + P N G S V E + P L
Sbjct: 31772 GEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANAECQEGQS-VCFEIRVSGIPPPTLK- 31827
Query: 250 IWKKDGVLLSGGISDH-------NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYL 302
W+KDG LS G + L I + D GYY V +++ S A+L
Sbjct: 31828 -WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR---VTATNTAGSTSCQAHL 31883
Query: 303 SV----LEPPQF--VKEPERHITAEMEKVV 326
V + +F +E ERH+ +++K +
Sbjct: 31884 QVERLRYKKQEFKSKEEHERHVQKQIDKTL 31913
Score = 38.5 bits (88), Expect = 0.073
Identities = 48/178 (26%), Positives = 71/178 (39%), Gaps = 11/178 (6%)
Query: 401 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESG- 458
AP I TV G G P P W K G +I S + + P ++
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW--YWPEDNVC 2134
Query: 459 SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVI---KGTQASM 515
L+I D+ + A N G + A L+V A+ IT + Q V+ K T A+
Sbjct: 2135 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATF 2194
Query: 516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVI 572
C T +P V ++ W KDG + R+ DR L I + D Y+C ++
Sbjct: 2195 ECE-TSEPFVKVK--WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Score = 37.4 bits (85), Expect = 0.16
Identities = 40/183 (21%), Positives = 75/183 (40%), Gaps = 14/183 (7%)
Query: 40 EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGA 99
+G + +L E + W +N+E K + ++ I L +R N G
Sbjct: 30457 DGGKEILGYWVEYRQSGDSAWKKSNKERIK---DKQFTIGGLLEATEYEFRVFAENETGL 30513
Query: 100 LLQRQTEVQVAYMGSFEEGE------KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
R+T + + + E K + GEAA + +I P P + W+R G++
Sbjct: 30514 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKE 30572
Query: 154 IPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPA 210
+ S + ++ + +TL +++ D G Y A N+ G+ +TS + L P
Sbjct: 30573 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEV-GEVETSSKLLLQATPQFHPG 30631
Query: 211 DPI 213
P+
Sbjct: 30632 YPL 30634
Score = 37.0 bits (84), Expect = 0.21
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGL 370
EP R + E + C+ G P P + WY + ++ K RFR R DG L I
Sbjct: 1848 EPVRVLEGETAR---FRCRVTGYPQPKVNWYLNGQLIRKSK--RFRVRYDGIHYLDIVDC 1902
Query: 371 VPDDTGMFQCFARNAAGEVQTSTYLAV 397
DTG + A N G ++ L +
Sbjct: 1903 KSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 37.0 bits (84), Expect = 0.21
Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 31/211 (14%)
Query: 139 SFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
S P + WFR+GR + P R +E + L I A D G+Y K D +T
Sbjct: 8769 SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQY-----TCKYEDLET 8823
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDG 255
S + + A+PI T I VV+ T EC + I + W K
Sbjct: 8824 SAELRI-------EAEPIQFTKRI---QNIVVSEHQSATFECEVSFDDAI---VTWYKGP 8870
Query: 256 VLLSGGISDHNRR------LTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQ 309
L+ + R +TI N T D G Y A L YL+ E
Sbjct: 8871 TELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKL 8930
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSI 340
+K P+ I + +P +A VPP I
Sbjct: 8931 ELKPPD--IPDSRVPIPTMPIRA--VPPEEI 8957
Score = 36.6 bits (83), Expect = 0.28
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 17/162 (10%)
Query: 56 LEFKWLHNN--------RELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEV 107
+E +WL NN ++ +R I + G YR I +++ + + ++
Sbjct: 12940 VEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK-----EARAKL 12994
Query: 108 QVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT 167
++A + ++ V G+ + P A +P+ + WF++ + + + +
Sbjct: 12995 ELAAAPKIKTADQDLVVDVGKPLTMVVPYDA-YPKAEAEWFKENEPLSTKTIDTTAEQTS 13053
Query: 168 LVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGP 209
IL D GRY + + +K+G K I L V +V GP
Sbjct: 13054 FRILEAKKGDKGRYKI-VLQNKHG--KAEGFINLKVIDVPGP 13092
Score = 36.2 bits (82), Expect = 0.36
Identities = 35/147 (23%), Positives = 56/147 (38%), Gaps = 10/147 (6%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE--------KHQSV 124
E +Y +T L +R + N G V E E + Q +
Sbjct: 17171 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 17230
Query: 125 SHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQ 184
G+ + A I P P+VTW ++ R P +RI +T + + + A + G Y
Sbjct: 17231 KVGDTLRLSAI-IKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 17289
Query: 185 AVNDKNGDNKTSQPITLTVENVGGPAD 211
V + G +KT L ++ G P D
Sbjct: 17290 TVENPAG-SKTVSVKVLVLDKPGPPRD 17315
Score = 35.4 bits (80), Expect = 0.61
Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 59 KWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEG 118
KW+ + + +E +T L+ YR NR GA + ++ + + E
Sbjct: 13633 KWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 13688
Query: 119 EKHQSVSHGEAAVIRA-------PRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTL 168
E V ++A + P+P++TW + + RI I ++T+
Sbjct: 13689 EIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTV 13748
Query: 169 VILSTVAPDAGRYYVQAVN 187
I+ + D G Y ++AVN
Sbjct: 13749 TIVDSKRSDTGTYIIEAVN 13767
Score = 35.0 bits (79), Expect = 0.80
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE--NTLVILSTVAPDAGRY 181
V GE A R R+ +PQP+V W+ +G+ I S R + + + L I+ + D G
Sbjct: 1852 VLEGETARFRC-RVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1910
Query: 182 YVQAVN 187
V A N
Sbjct: 1911 KVTAEN 1916
Score = 35.0 bits (79), Expect = 0.80
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 505 QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD-RNGSLHISQTWSGD 563
+S G+ A C V+ +T W KDG+ + R D ++ LHI D
Sbjct: 11128 ESEFVGSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSD 11184
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLP 590
G YTC + + +A L V +LP
Sbjct: 11185 AGEYTCVLRLGNKEKTSTAKLVVEELP 11211
Score = 34.7 bits (78), Expect = 1.0
Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 53 SWPLEFKWLHNNREL-TKFS--LEYRYMITSLDRTHAGFYRCIVRNRMGALLQ-RQTEVQ 108
S+ +E + L N R L FS LE + ++ L A +R I +N GA+ +
Sbjct: 21390 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 21449
Query: 109 VAYMGSFEEGEKHQSVSHGEAAVIRAPR-------IASFPQPQVTWFRDGRKIPPSSRIA 161
+ E + V + +++A ++ P P + W +DG+++ ++++
Sbjct: 21450 ITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE 21509
Query: 162 ITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTII 218
I + LV + D+G Y + A N G K + + ++ G P P+A T +
Sbjct: 21510 IKIADFSTNLVNKDSTRRDSGAYTLTATN-PGGFAKHIFNVKV-LDRPGPPEGPLAVTEV 21567
Query: 219 IPPK 222
K
Sbjct: 21568 TSEK 21571
Score = 34.7 bits (78), Expect = 1.0
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILS---TVAPDAGRYYVQAVNDKNGDNKTSQ 197
PQ V W +DG+ + ++R+ ++ T+ LS D G Y + N +
Sbjct: 25422 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV---SNSAGSITV 25478
Query: 198 PITLTVENVGGPADPI 213
PIT+ V + GP PI
Sbjct: 25479 PITIIVLDRPGPPGPI 25494
Score = 33.5 bits (75), Expect = 2.3
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRI-AITLENT--LVILSTVAPDAG 179
+V GE + P I P P VTW +D + ++R+ A + EN L I D G
Sbjct: 22158 TVLAGEDLKVDVPFIGR-PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVG 22216
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPI 213
Y V+ N +T I L + G P P+
Sbjct: 22217 HYVVKLTNSAGEAIETLNVIVL--DKPGPPTGPV 22248
Score = 33.1 bits (74), Expect = 3.0
Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 18/155 (11%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQV-----AYMG-------SFEEGEK 120
E +++I+ L + +R RN +G++ V +Y G + E K
Sbjct: 26824 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVK 26883
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR 180
+++ G + +RA I+ P P + W++D +++ ++ + + ENT + S + DA R
Sbjct: 26884 YRA---GTSVKLRAG-ISGKPAPTIEWYKDDKELQTNALVCV--ENTTDLASILIKDADR 26937
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAP 215
K + S T+ V+ + P P P
Sbjct: 26938 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGP 26972
Score = 31.6 bits (70), Expect = 8.9
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 1/86 (1%)
Query: 427 GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA 486
G P + W + L + + +L SL + D+G TC ATN G D
Sbjct: 1730 GDPTMVVEWLHDGKPLEAAN-RLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHT 1788
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQ 512
SA L+V + + Q KG Q
Sbjct: 1789 SATLIVKDEKSLVEESQLPEGRKGLQ 1814
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 246 bits (629), Expect = 1e-64
Identities = 395/1726 (22%), Positives = 665/1726 (38%), Gaps = 198/1726 (11%)
Query: 147 WFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
W ++G ++P +R++ ++ + L I PD G Y V A DK S L +
Sbjct: 6461 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDK------SVAELLII 6514
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS 263
E APT + V + C + K ++ W ++G + G
Sbjct: 6515 E---------APTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKK 6562
Query: 264 ------DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE-PER 316
RL I + D Y C R S V + ++ PPQ + E P
Sbjct: 6563 YKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGA 6622
Query: 317 HIT--AEMEKVVDIPCQAKGVPPPSITWYKD-AAVVEVEKLTRFRQRNDGGLQISGLVPD 373
+ AE+ K + W ++ VV+ +K + LQI + P
Sbjct: 6623 DVVFLAELNK-----------DKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR 6671
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D G ++ A++ E + LA AP I D V G + + P+
Sbjct: 6672 DQGEYRFIAKDK--EARAKLELAA---APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEA 6726
Query: 434 TWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW 493
W K L++ ++ T E S I D G Y + N G E +L V
Sbjct: 6727 EWFKENEPLSTKTID----TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV- 6781
Query: 494 ARTRITKPPQDQSVIKGTQASMVCG----VTHDPRVTIRYIWEKDGATLGTESHPRIRLD 549
+ P ++ V + + +T I Y+ E+ T + D
Sbjct: 6782 --IDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV---LATD 6836
Query: 550 RNGSLHISQTWSGDIGT-YTCRV-----ISAGGNDSRSAHLRVRQLPHAPEHPV-ATLST 602
R S + T G Y RV + G + R P P+ T++
Sbjct: 6837 RAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITD 6896
Query: 603 VERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSY 661
V R ++LTW P +DG + + Y++E+ + + +V + S TV +V + Y
Sbjct: 6897 VNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEY 6956
Query: 662 QFRLCAVNDVGKGQFSKDTE--RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
FR+ A N +G G+ S T +V+ P E P+ PP N+ +S +T S+ ++W+PP +
Sbjct: 6957 SFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSSVQLKWEPPLKDGG 7015
Query: 720 NGILKGYIIRYCLAGLP--VGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
+ IL GYII C G + K + + LE Y V+A N AG+
Sbjct: 7016 SPIL-GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK---GNKYLYRVSAENKAGVSD 7071
Query: 778 YSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837
S + T P ++ A I P+P I + GY
Sbjct: 7072 PSEILGPLTADDAFVEPTMDLSAFKDGLEVI-----VPNPITILVPSTGYP--------- 7117
Query: 838 EEVTMVTARPNFQDSI-HVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG 896
TA F D + G +K + Y V+ + D T +L + + G
Sbjct: 7118 ----RPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7173
Query: 897 PVG-----------HLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR-TNTRVT 943
+ L F +I S+ ++W+ P + G LTGY + E +R T T+V
Sbjct: 7174 EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVM 7233
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA--STISSGVPPELPGPPTNLGI 1001
++ + LE+ V L Y +V A G G+ + ++ P +P PP N+
Sbjct: 7234 DFVTD--LEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKW 7291
Query: 1002 SNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS-MEVP 1059
+ S+ L + P DG + I ++VE ++W+ EP A + MEV
Sbjct: 7292 RDRTANSIFLTWDPPKNDGGSRIKGYIVER---CPRGSDKWVAC----GEPVAETKMEVT 7344
Query: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTL--QAPPDM-----APANVSLRTASETS 1112
L Y++R++ +N G S PS+P+ +IQ + Q P++ A ++++ ++
Sbjct: 7345 GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIE 7404
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER--DYTIEDLEEWTE 1170
L G PE KI ++++D K + + V + TI D +
Sbjct: 7405 L--------PATVTGKPEP---KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7453
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
++A N G T V P T+ S L+ W+ P D
Sbjct: 7454 GTYIIEAVNVCGRA----TAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP-PRDDGGS 7508
Query: 1231 LVLGYKVMYKEKDSDTQPRF-WLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-S 1288
+ Y V + DS+ + V+ + ++ +L +Y+ +V A G G P
Sbjct: 7509 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF---RVAAENMYGVGEPVQ 7565
Query: 1289 HPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTA 1348
PI + D PGPP + ++ +V L W P G + RL+ T
Sbjct: 7566 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7625
Query: 1349 TVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRP 1406
+ Y GL + Y FR+ A+ G G+ +++ ++ + D P PP +P
Sbjct: 7626 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKP 7685
Query: 1407 MVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDR 1465
V +DV SV L+W +P DG + + Y I+ + + W + V + ++
Sbjct: 7686 TV--KDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVP--TTQHLLPG 7741
Query: 1466 LKPFTSYKFRVKATNDIGDSEFSEESES-LTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
L Y FRV+A N G+SE SE S+ L + P P L V T + ++W
Sbjct: 7742 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 7801
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
P +D + + + R++ +G W + + + LT+
Sbjct: 7802 PEKDG-GSPITNYIVEKRDVRRKG---------------WQTVDTTVKDTKCTVTPLTEG 7845
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT--AAPRNVVVHGATATQLDV 1642
L Y R++ NA+G+ + ++ + + T P + V T +D+
Sbjct: 7846 SL--------YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7897
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
WEPP D IQ Y I E + KT + + ++ ++ T V A
Sbjct: 7898 KWEPPKNDG-GRPIQRYVIEKKERLGTRWVKAGKTAG-PDCNFRVTDVIEGTEVQFQVRA 7955
Query: 1703 FNAAGDGPRSTPTQ---GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
N AG G S PT+ + + PS P + ++ + ++W+ P+ G + GY
Sbjct: 7956 ENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYH 8015
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD-LAEGVTYRFRIRA 1803
+ E C PV G K + V+ + L KV++ + Y R+RA
Sbjct: 8016 V--EMC-PV-GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 8057
Score = 225 bits (573), Expect = 4e-58
Identities = 433/1960 (22%), Positives = 731/1960 (37%), Gaps = 276/1960 (14%)
Query: 72 LEYRYMITSLDRTHAGFYRCIVRNRMGAL---------LQRQTEVQVAYMGSFEEGEKHQ 122
+E ++ ++ L +R I +N GA+ + + EV++ + +
Sbjct: 17271 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 17330
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTLVILSTVAPDAG 179
V+ GE + A + P P + W R ++I S+R I + L++ + D G
Sbjct: 17331 VVNAGETFRLEAD-VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 17389
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVA 239
+Y ++A N S P+ + V + GP P V TSE
Sbjct: 17390 QYILRA---SNVAGSKSFPVNVKVLDRPGP----------PEGPVQVTGVTSE------- 17429
Query: 240 NARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAG-YYECEAVLRSSSVPSVVR 298
K + W L G SD + + T A E V S V ++
Sbjct: 17430 ------KCSLTWSPP---LQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLE 17480
Query: 299 G---AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV------ 349
G + + V EP M+ +P K + +I KD+ V
Sbjct: 17481 GNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIA--KDSMTVCWNRPD 17538
Query: 350 ----------EVEKLTRF---------RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQ 390
VEK R R+ D L+++GL D F+ A NAAG +
Sbjct: 17539 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17598
Query: 391 TS-TYLAVTSIAPNITRGP------LDST-----------VIDGMSVVLA-----CETSG 427
S + + P GP +D+T + DG S +L C+
Sbjct: 17599 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 17658
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA- 486
+T Q G R+ T E L T + C A N G+ EA
Sbjct: 17659 EEWQIVTPQTGLRV-----------TRFEISKL----TEHQEYKIRVC-ALNKVGLGEAT 17702
Query: 487 SADLVVWARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
S V ++ P D + ++ S + R T W ++
Sbjct: 17703 SVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---- 17758
Query: 541 ESHPRIRLDRNGS---LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
E ++++++ + L I D G Y ++ ++ G+ S ++V P P++
Sbjct: 17759 EFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-- 17816
Query: 598 ATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLV 656
+ V + + L W P DG + + Y+++ E+ ++S K TS V+ L
Sbjct: 17817 LAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLT 17875
Query: 657 PARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPE 716
Y FR+ A N+ G G + + V E P +PP V + + S + W+ P
Sbjct: 17876 EGAIYYFRVMAENEFGVGVPVETVDAVKAAE--PPSPPGKVTLTDVSQTSASLMWEKPEH 17933
Query: 717 SHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG 776
+ +L GY++ G ++ + ++ V N ++ L Y+ V AYN G
Sbjct: 17934 DGGSRVL-GYVVEMQPKGTE---KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKG-- 17987
Query: 777 VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF-------INGINQGYKL 829
++ + GVP + + T +++ +N S Q I I +
Sbjct: 17988 -----KSDPRVLGVPVIA-----KDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 18037
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
I+W ++ E T R N +++ V +K+ + T +T L
Sbjct: 18038 ISW--VKDGEPLKQTTRVNVEETA-TSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 18094
Query: 890 THEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLP 947
+ PG PVG + F E+ + +SW+ P G ++ Y + R T T ++
Sbjct: 18095 IVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMV 18150
Query: 948 NVTL---EYRVTGLTALTTYTIEVAAMTSKGQ-GQVSASTISSGVPPELPGPPTNLGISN 1003
+ T+ ++T L T Y + A G+ + + + P + PGPP +++
Sbjct: 18151 SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTS 18210
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I + +Q+ P DG T I + +E + E L + + L+
Sbjct: 18211 ISKDQMLVQWHEPVNDGGTKIIGYHLEQK-----EKNSILWVKLNKTPIQDTKFKTTGLD 18265
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPE 1122
Y F++ NIVG PS+ S + P P + ++ L+W +
Sbjct: 18266 EGLEYEFKVSAENIVGIGKPSKVSECF--VARDPCDPPGRPEAIVITRNNVTLKW---KK 18320
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G + GY ++ + G+ + + +E ++T+ L E Y +V A NA G
Sbjct: 18321 PAYDGGSKITGYIVE-KKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 18379
Query: 1183 --SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE--VPEADRNGLVLGYKVM 1238
S P + R+ + + N S ++V E V EAD G + V
Sbjct: 18380 NFSEPSDSSGAITARDEIDA---PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 18436
Query: 1239 YKE-KDSDTQPRFWLVEGNSSRSAQL------TGLGKYVLYEVQVLAFTRIGDGSPSHPP 1291
K+ K+ + ++ ++ + T G+Y+L V G P
Sbjct: 18437 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNV--------GGTKSIP 18488
Query: 1292 ILERTLDDVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATV 1350
I + LD PGPP G L V L W PP G +++ I + T+ + V
Sbjct: 18489 ITVKVLDR-PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 18547
Query: 1351 EVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTT-EKRDRPQPPSRPMVQ 1409
A Y T L P + Y+FR+ A + G GE E+ VT P PPS P V
Sbjct: 18548 ST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVS 18606
Query: 1410 QEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKP 1468
+ S++++W P DG + + Y ++ R+ RW + + V L
Sbjct: 18607 A--ITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDL-RLRVTGLTE 18663
Query: 1469 FTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAE 1527
SY+FRV A N G E SE S A P P+ VT + +SV + W P
Sbjct: 18664 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKP-- 18721
Query: 1528 DKINGILLGFRIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
+Y+G ++G+ + W T ++ Q+
Sbjct: 18722 -----------------IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG------KQF 18758
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAVP------TAAPRNVVVHGATA 1637
+ L ++ Y R+ N+ G G P++ P V E + A R VVV A+A
Sbjct: 18759 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18818
Query: 1638 T-QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE-NSVKLKNLTGYTA 1695
T +L VT + P WE G LT+R + + + + N+T + +
Sbjct: 18819 TLRLFVTIKGRPEPEVK----------WEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDS 18868
Query: 1696 YMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILE 1755
++ N +G T +PSAP ++ E+ SV +SWE P G
Sbjct: 18869 GRYNLTLENNSGS---KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGA-- 18923
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN 1815
++ + K + ++++L EG +Y FR+ A YG + A
Sbjct: 18924 --KITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASN-EYGIGLPAE 18980
Query: 1816 VTTGPGEGA--PGPPG-VPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDI 1871
TT P + + P PPG V ++ + I W + G IT YV+E + W
Sbjct: 18981 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 19039
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
+V + ++ L G Y FRV AVN+ G P
Sbjct: 19040 C-----TQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDP 19074
Score = 218 bits (556), Expect = 4e-56
Identities = 418/1900 (22%), Positives = 731/1900 (38%), Gaps = 252/1900 (13%)
Query: 136 RIASFPQPQVTWFRDGRKIPPS----------SRIAITLENTLVILSTVAPDAGRYYVQA 185
+I P P +TWF+ K P + +++ + TLVI + D G Y + A
Sbjct: 9834 KIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITA 9893
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTII------------IPPKNTSVVAGTSEV 233
VN+ +K + + +G P P+ P PPK+ T+ V
Sbjct: 9894 VNNLGTASKE-----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9948
Query: 234 TLECVANARPLIKLHIIWKKDGVLLSGGISDHNR--RLTIPNPTG-SDAGYYECEAVLRS 290
+ AN + + + K+ + + H R+ N G + E E
Sbjct: 9949 IEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 10008
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY--KDAAV 348
SVP + P +T E+ + G P + W KD
Sbjct: 10009 FSVPGAP--------DKPTVSSVTRNSMTVNWEEP-----EYDGGSPVTGYWLEMKDTTS 10055
Query: 349 VEVEKLTR--FRQRNDG-GLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIA 401
+++ R + G +++GL+ F+ +A NAAG + + A IA
Sbjct: 10056 KRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 10115
Query: 402 P---------NITRGPLD----STVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQ 448
P + T+ D + DG S V W+KG+ G+
Sbjct: 10116 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 10175
Query: 449 LPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE-ASADLVVWARTRITKPP----- 502
+ T L+ G+ + A N G+ E V+ + R+ P
Sbjct: 10176 V--VTGLKEGAFY----------KFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 10223
Query: 503 --QDQSVIK-GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
+D+ V+ G ++ V+ P T+ W + TL E+ + S+ I
Sbjct: 10224 SVRDRIVVHAGGVIRIIAYVSGKPPPTVT--WNMNERTLPQEATIETTAI-SSSMVIKNC 10280
Query: 560 WSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-G 618
G Y+ + G ++ + V +P P + + LTW P D G
Sbjct: 10281 QRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA-HNLTNESCKLTWFSPEDDG 10339
Query: 619 NSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS 677
SP+ Y++E E++ WT + +V + + TV+GL+ ++Y FR+ A N +G G F
Sbjct: 10340 GSPITNYVIEKRESDRRAWTPVTYTVTRQ--NATVQGLIQGKAYFFRIAAENSIGMGPFV 10397
Query: 678 KDTERVSLPEEPPTAP--PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGL 735
+ +E + + EP T P P+++ T ++ + W PP + G II Y L
Sbjct: 10398 ETSEALVI-REPITVPERPEDLEVKEVTKNTVTLTWNPP--KYDGG---SEIINYVLESR 10451
Query: 736 PVGYQ-FKNITDADV--NNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPT 792
+G + F +T+ ++ ++ L YE V+A N G G S T +
Sbjct: 10452 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKD--E 10509
Query: 793 VPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQ----EEEVTMVTARPN 848
+ P +H + + TIR +G + ++W ++ E++ T + P
Sbjct: 10510 LAPPTLHLDFRDKLTIRVGEAFALTGRYSG--KPKPKVSWFKDEADVLEDDRTHIKTTPA 10567
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILD 908
++ + + + + + V+ +T G R V + PVG +SF E+
Sbjct: 10568 ---TLALEKIKAKRSDSGKYCVVVENST---GSRKGFCQVNVVDRPGPPVGPVSFDEVTK 10621
Query: 909 TSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVTLEYRVTGLTALTTYTI 966
+ +SW+ P + G +T Y I +E + VT T +V+ L Y
Sbjct: 10622 DYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC--KVSKLLEGKDYIF 10679
Query: 967 EVAAMTSKGQGQVSASTISSGVPPE----LPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
+ A G +S +S + + +P P ++ + S + + +DG
Sbjct: 10680 RIHAENLYG---ISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKP 10736
Query: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
I+ +++E + + + W + + P + VPDL Y FR+ N +G P
Sbjct: 10737 ITNYILEKRETM---SKRWARVTKDPIHPYTK-FRVPDLLEGCQYEFRVSAENEIGIGDP 10792
Query: 1083 SQPSRKIQTLQ--APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR 1140
S PS+ + A P P N + S+ L W P ++G + +GY ++Y +
Sbjct: 10793 SPPSKPVFAKDPIAKPS-PPVNPEAIDTTCNSVDLTWQP---PRHDGGSKILGYIVEYQK 10848
Query: 1141 -SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRE 1196
D + +H + E Y + L + Y+ +V A NA G + + V+ + R
Sbjct: 10849 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10908
Query: 1197 SVPS-------SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD--TQ 1247
P + ++ T S +++ P KV +K++D D T+
Sbjct: 10909 EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP-----------KVTWKKEDRDAPTK 10957
Query: 1248 PRFWLVEGNSS---RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1304
R + S R+A G Y L + + + S ++ + D PGPP
Sbjct: 10958 ARIDVTPVGSKLEIRNAAHEDGGIYSL---------TVENPAGSKTVSVKVLVLDKPGPP 11008
Query: 1305 MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
+ E+R S L W+ P G ++ + R + +A + + + + + A
Sbjct: 11009 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK-KSHFAKH 11067
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSW- 1422
L + YLFR+ A+ + G G E + D PP P + DV V L W
Sbjct: 11068 LNEGNQYLFRVAAENQYGRGPFVET-PKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 11126
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
+P DG SP+ Y ++ +E + W + +V L+ +Y+FRVKA N +
Sbjct: 11127 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC---VVTGLQQGKTYRFRVKAENIV 11183
Query: 1483 GDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK----INGILL--G 1536
G PD + P L+ PP+ + I G+++ G
Sbjct: 11184 G--------------LGLPD------TTIPIECQEKLV---PPSVELDVKLIEGLVVKAG 11220
Query: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWA------ELTSMYSMRNLSRPSLTQYELDNLN 1590
+R+ ++ RG+ P A W + Y++ + S+ + N
Sbjct: 11221 TTVRFPAII---------RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT--IKNCL 11269
Query: 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+ E +++V NA G + V PT P N++ T + ++W+PP D
Sbjct: 11270 RRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINIL--DVTPEHMTISWQPPK-D 11325
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
+ Y + + ++ T V + ++ +K+ +L Y+ V A N G GP
Sbjct: 11326 DGGSPVINYIVEKQDTRKD--TWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGP 11383
Query: 1711 R--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPV 1767
STPT + + + PS P +++T + VSW P+ G + GY Y V
Sbjct: 11384 PLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGY---YMERREV 11440
Query: 1768 DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTTGPGEG 1823
G K V V+ + L +V L EG TY FR+ A+ P + P +
Sbjct: 11441 TG--KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK- 11497
Query: 1824 APGPPGVPIIVRYSSAIA-IHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
PGPP P + S A + W+ G PI YV+E + W+ + KD + +
Sbjct: 11498 PPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD--ELIR 11555
Query: 1882 SYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
F + L G Y FR+ A N G G P ++SV A+
Sbjct: 11556 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAK 11595
Score = 215 bits (548), Expect = 3e-55
Identities = 424/1882 (22%), Positives = 697/1882 (37%), Gaps = 278/1882 (14%)
Query: 378 FQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMSVVLACETSGAP 429
F+ A+N AG E +S + I P + + +I G + SG P
Sbjct: 22311 FRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRP 22370
Query: 430 RPAITWQKGE-RILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASA 488
P +TW+ E R+ + V + T + +L + + D+G Y N+ GV S
Sbjct: 22371 APKVTWKLEEMRLKETDRVSIT--TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV 22428
Query: 489 DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--IRYIWEK--DGATLGTESHP 544
+VV R P + S + + G D T YI EK G T +
Sbjct: 22429 TVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNS 22488
Query: 545 RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLST-- 602
++ + H+++ Y+ RV S + + P EHP S
Sbjct: 22489 SVKRTQIKVTHLTKYME-----YSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPT 22540
Query: 603 ------VERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGL 655
V A+++ W +P+ DG S +I Y +E E N V V + V GL
Sbjct: 22541 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22600
Query: 656 VPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPP 715
V YQFR A+N G + S + R + + P AP + + T ++ + W P
Sbjct: 22601 VEGLEYQFRTYALNAAGVSKAS-EASRPIMAQNPVDAPGRPEVTDV-TRSTVSLIWSAPA 22658
Query: 716 ESHQNGILKGYII-RYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSA 773
+ ++ GYII R ++ + G K N T N + L YE V A N+A
Sbjct: 22659 YDGGSKVV-GYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAA 22717
Query: 774 GLGVYSSKVTEWTLQGVPTVPP-----GNVHAEATNSTTIRFTWNAPSPQFINGINQGYK 828
G+ S+ T PP +H + TIR + + G + K
Sbjct: 22718 GVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV---TIRAGSDLVLDAAVGGKPEP-K 22773
Query: 829 LIAWEPEQE----EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRST 884
+I + ++E E+V++ I S K+T + G ++
Sbjct: 22774 IIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA-------SGTKAV 22826
Query: 885 PQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVT 943
+V+ D PGP G L+ S + ++W P E G +T Y + E +R N +
Sbjct: 22827 SVMVKVL-DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 22885
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG-QVSASTI---SSGVPPELPGPPTNL 999
TL Y VT L Y V A+ G G V + I +S P PG P +
Sbjct: 22886 EG-ECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEV 22944
Query: 1000 GISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEV 1058
G G + +Q+ +P DG IS +LV+ + + W +++ D R ++V
Sbjct: 22945 GT---GKEHIIIQWTKPESDGGNEISNYLVDKREK---KSLRWTRVNKDYVVYDTR-LKV 22997
Query: 1059 PDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP----PDMAPANVSLRTASETSLW 1114
L Y FR+ VN G S PS+ S I + P AP V S + W
Sbjct: 22998 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 23057
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
+ M Y+G + VGY ++ D H ++T+ DL+ +Y +
Sbjct: 23058 TKPM------YDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFR 23111
Query: 1175 VQAFNAIGSGPWSQTVVGRT---RESVPSSGPTN-----VSALATTSSSMLVRWSEVPEA 1226
V A N G +S+++ R +P + V+ A S ++V S P
Sbjct: 23112 VAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP 23171
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
+ + ++ D R + +++ S L + K Y+
Sbjct: 23172 ---------VITWSKQGIDLASRAII---DTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23219
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+L + D PGP + EV SV + W+ P G + I +
Sbjct: 23220 KKSATVLVKVYD-TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRA 23278
Query: 1347 TATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPS 1404
TV S Y +GL ++Y FR+ + G GE E V+ +E P P+
Sbjct: 23279 FKTVTTKC-SKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PLVPA 23334
Query: 1405 RPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
+ ++ DV +V L+WE P DG S + Y ++ + + RW + ++ V
Sbjct: 23335 K--LEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW-MKVVTLKPTVLEHTV 23391
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRW 1522
L Y FR++A N+ G SE E ++T PTI LS P T V
Sbjct: 23392 TSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRV--LPTIDLSTMPQKTIHV---- 23445
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLT 1582
PA + ++ + G P A+W S +R R ++
Sbjct: 23446 --PAGRPVELVI------------------PIAGRPPPAASWFFAGS--KLRESERVTVE 23483
Query: 1583 QYELDNLNKHRRYEIRMSVYNAVGE---------GPSSPPQEVFV-GEAVPTAAPRNVVV 1632
+ K + IR + GE G +S +V + + P P + +
Sbjct: 23484 TH-----TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP--IKI 23536
Query: 1633 HGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTG 1692
AT + ++WEPP LD + GY + +A R +++ ++ K LT
Sbjct: 23537 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTE 23593
Query: 1693 YTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Y+ VAA N G G +S + ++ P P +++ +++ + ++W P+
Sbjct: 23594 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23653
Query: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
G V+ + + + W++V + +T R R+ T G
Sbjct: 23654 GG---------------SQVTGYIVERKEVRADRWVRVNKVPVTMT---RYRSTGLTEGL 23695
Query: 1811 EIEANVTT--GPGEGAPGPPGVPIIVR-----------------YSSAIAIHWS-SGDPG 1850
E E VT G G P P PI+ +++++ WS D G
Sbjct: 23696 EYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEG 23755
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
+T Y+IE + D+ W P ++ YT + L G Y FRV+A N G G
Sbjct: 23756 GSKVTGYLIEMQKVDQHEWT-KCNTTPTKIREYTLTH--LPQGAEYRFRVLACNAGGPGE 23812
Query: 1911 PSSPSQSV--------PAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAK 1962
P+ +V P + + Y+E F+ ++ L + I+G+ K
Sbjct: 23813 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRL--------TIPIKGKPFPICK 23864
Query: 1963 KTDSGNSAKSGAL-----GHSEMMSLD----ESSFPALELNNRRLSVKNSFCRKNGLYTR 2013
T G A+ H+E++ + +S L L N+ C K +Y +
Sbjct: 23865 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENK--------CGKKAVYIK 23916
Query: 2014 SPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSF 2073
SP S E +Y+D I S ++ +P +D G+D +
Sbjct: 23917 VRVIGSPN----SPEGPLEYDD-IQVRSVRVSWRPP--ADDGGADI---------LGYIL 23960
Query: 2074 VNHYISDPTYYNSWRRQQ------KGISRAQAYSYTESDSGEPDHTTVTNSTSTQQGSLF 2127
+ +Y R + KG+ Y + S + Q +
Sbjct: 23961 ERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVS--------------AENQFGIS 24006
Query: 2128 RPKASRTP----TPQNPPNPPS 2145
+P S P TP NPP PPS
Sbjct: 24007 KPLKSEEPVTPKTPLNPPEPPS 24028
Score = 213 bits (541), Expect = 2e-54
Identities = 413/1864 (22%), Positives = 693/1864 (37%), Gaps = 243/1864 (13%)
Query: 147 WFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
WFR+ I SS+ I ++ TL I D Y V N + + K++ + +
Sbjct: 6367 WFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEE 6426
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV------L 257
E++ I+ P K+ + S VT C N + + + W K+G
Sbjct: 6427 EDL---------RIVEPLKDIETMEKKS-VTFWCKVNR---LNVTLKWTKNGEEVPFDNR 6473
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP-QFVKEPER 316
+S + + LTI + D G Y ++ + SV A L ++E P +FV+ E
Sbjct: 6474 VSYRVDKYKHMLTIKDCGFPDEGEY----IVTAGQDKSV---AELLIIEAPTEFVEHLED 6526
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ---ISGLVPD 373
E + V CQ ++ WY++ E+++ +++ DG + I D
Sbjct: 6527 QTVTEFDDAV-FSCQLSR-EKANVKWYRNGR--EIKEGKKYKFEKDGSIHRLIIKDCRLD 6582
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D + C + + L V I I R P D G VV E + + +
Sbjct: 6583 DECEYACGVEDRKSRAR----LFVEEIPVEIIRPPQDILEAPGADVVFLAELN-KDKVEV 6637
Query: 434 TWQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAGTYTCLATNSRGVDEASADL 490
W + ++ G + + G L I D G Y +A + EA A L
Sbjct: 6638 QWLRNNMVVVQGD----KHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKL 6689
Query: 491 VVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR 550
+ A +I QD V G +MV V +D W K+ L T++
Sbjct: 6690 ELAAAPKIKTADQDLVVDVGKPLTMV--VPYDAYPKAEAEWFKENEPLSTKTIDTTA--E 6745
Query: 551 NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER--RAI 608
S I + GD G Y + + G +L+V +P PV L E +
Sbjct: 6746 QTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPG----PVRNLEVTETFDGEV 6801
Query: 609 NLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPAR-SYQFRLC 666
+L W +P DG S +I Y++E + T +LA+ ++ TV GL Y FR+
Sbjct: 6802 SLAWEEPLTDGGSKIIGYVVERRDIKRK-TWVLATDRAESCEFTVTGLQKGGVEYLFRVS 6860
Query: 667 AVNDVGKGQ-FSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKG 725
A N VG G+ D + + PP NV + + + W+ PPE +
Sbjct: 6861 ARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWE-PPEYDGGAEITN 6919
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
Y+I + + A+ + + D++ Y V A N G+G S T +
Sbjct: 6920 YVIE-LRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVG-KPSAATPF 6977
Query: 786 TLQGVP---TVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
P PP N+ + ++++ W P + G ++ + E+ EE
Sbjct: 6978 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK------DGGSPILGYIIERCEEGKD 7031
Query: 843 VTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHL 901
R N + + + V+GL+K +Y V G V ++ GP+
Sbjct: 7032 NWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG---------VSDPSEILGPL--T 7080
Query: 902 SFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLE----YRVTG 957
+ ++ ++ +S + G + + I T + LE ++
Sbjct: 7081 ADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKT 7140
Query: 958 LTALTTYTIEVAAMTSKG----QGQVSASTISSGVPPEL---PGPPTNLGISNIGPRSVT 1010
L+A I + + KG + + TIS + + P P L +I SV
Sbjct: 7141 LSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVH 7200
Query: 1011 LQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSF 1069
L + P DG + ++ ++VE + + W + + + VPDL Y F
Sbjct: 7201 LTWEPPDDDGGSPLTGYVVEKR---EVSRKTWTKVMDFVTDLE---FTVPDLVQGKEYLF 7254
Query: 1070 RMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
++ N G P+ + T PD P NV R + S++L W P + +G
Sbjct: 7255 KVCARNKCGPGEPAYVDEPVNMSTPATVPD-PPENVKWRDRTANSIFLTWDP---PKNDG 7310
Query: 1128 NPESVGYKIKY--SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
GY ++ SD V + ++E + LEE Y +V+A N G
Sbjct: 7311 GSRIKGYIVERCPRGSDKWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASK 7366
Query: 1183 -SGPWSQTVVGRTRE--------------SVPSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
S P + T+E +V + + A T + W++
Sbjct: 7367 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKA---- 7422
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++L ++ + +V+ S + G Y++ V V
Sbjct: 7423 --DMILKQDKRITIENVPKKSTVTIVDSKRSDT------GTYIIEAVNVCG--------- 7465
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILA----------YQIT 1337
++E + D PGPP +V S L W PP G + ++
Sbjct: 7466 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 7525
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKR 1397
H+L++T +T + AT L P Y+FR+ A+ G GE +A +T + +
Sbjct: 7526 HKLSSTVKDT-----------NFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ 7574
Query: 1398 -DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
D P PP+R ++ D+ +V L+W EP DG SP+ Y ++ + + +W + +
Sbjct: 7575 FDPPGPPTR--LEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW-VRCNKMP 7631
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVT 1511
+++ V L Y+FRV A N G + S+ +E + P PT+ V
Sbjct: 7632 VKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDV- 7690
Query: 1512 PHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMY 1571
TSV + W P D G +I + + + W
Sbjct: 7691 --GKTSVRLNWTKPEHDG------GAKI----------ESYVIEMLKTGTDEW------- 7725
Query: 1572 SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAV-PTAAPRN 1629
+R TQ+ L L + + Y R+ N GE PS P V E + P + PR
Sbjct: 7726 -VRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRW 7784
Query: 1630 VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKN 1689
+ V T D+ W P D I Y + + +R + V T + + +
Sbjct: 7785 LEVINITKNTADLKWTVPEKDG-GSPITNYIVEKRDVRRKG-WQTVDTT-VKDTKCTVTP 7841
Query: 1690 LTGYTAYMVSVAAFNAAGDGPRS---TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEA 1746
LT + Y+ VAA NA G + + P P ++ ++T V++ WE
Sbjct: 7842 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEP 7901
Query: 1747 PQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTF 1806
P+ G R V E + ++ V +V D+ EG +F++RA+
Sbjct: 7902 PKNDGG-RPIQRYVIEKKERLG--TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENE 7958
Query: 1807 TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA----IAIHWSSGDP-GKGPITRYVIEA 1861
E PP P+ + + A IAI W + G PI Y +E
Sbjct: 7959 AGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM 8018
Query: 1862 RPSDEGLWDIL----IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
P W + IKD+ +V + + P Y RV AVN G PS S++
Sbjct: 8019 CPVGTEKWMRVNSRPIKDLKFKVE------EGVVPDKEYVLRVRAVNAIGVSEPSEISEN 8072
Query: 1918 VPAQ 1921
V A+
Sbjct: 8073 VVAK 8076
Score = 213 bits (541), Expect = 2e-54
Identities = 357/1619 (22%), Positives = 619/1619 (38%), Gaps = 152/1619 (9%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQ--TSTYLAVTSI----APNITRGPLDSTVI---DGM 417
+SGLV D F+ ARNAAG + + A+T+ APN + P VI G
Sbjct: 18359 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGE 18418
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ VL + G P P + W K + L + ++ + ++ +L++ +D G Y
Sbjct: 18419 TFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 18478
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT------IRYIW 531
+N G + V R PP+ + G A C + +P + YI
Sbjct: 18479 SNVGGTKSIPITVKVLDRPG---PPEGPLKVTGVTAEK-CYLAWNPPLQDGGANISHYII 18534
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAHLRVR 587
EK + + + + +L+ T Y RV++ G S +
Sbjct: 18535 EKRETSRLSWTQVSTEVQ---ALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC 18591
Query: 588 QLPHAPEHPVAT--LSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVD 644
P+ P P +T +S + + ++ +TW +P D G + + YILE +
Sbjct: 18592 N-PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT 18650
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQNVIASGRT 703
+ V GL SY+FR+ A N G G+ S+ + + P PP N + +
Sbjct: 18651 LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 18710
Query: 704 NQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGL--------PVGYQFKNITDADVNNLLL 754
S+ + W P + G +KGY++ A P G Q K T +
Sbjct: 18711 RSSVSLAWSKP--IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN-- 18766
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
T Y + A NS G+G ++ Q + P + +A + +A
Sbjct: 18767 ------TEYNFRICAINSEGVGEPATLPGSVVAQ--ERIEPPEIELDADLRKVVVLRASA 18818
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
F+ + + WE + E + A+ S + + + +F ++
Sbjct: 18819 TLRLFVTIKGRPEPEVKWE--KAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 18876
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G ++ VR + PV +L+ E+ S+ +SW+ P G +T Y +
Sbjct: 18877 NNSGS--KTAFVNVRVLDSPSAPV-NLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18933
Query: 934 EYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R +T+ T +R+ L +Y V A G G + A T E
Sbjct: 18934 ETTRKAYATITNNCTKTT--FRIENLQEGCSYYFRVLASNEYGIG-LPAETTEPVKVSEP 18990
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
P PP + + ++ + T+++ +P DG + I+ ++VE Q E+W Q+
Sbjct: 18991 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKT-- 19045
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTAS 1109
+ L Y FR+ VN G S P Q + + ++ P + + +
Sbjct: 19046 --LEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKA 19103
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
L + ++ + G P++ + + + G+TL + V T+ L
Sbjct: 19104 REQLKI------DVPFKGRPQAT---VNWRKD---GQTLKETTRVNVSSSKTVTSLSIKE 19151
Query: 1170 EYRVQVQAF-----NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVP 1224
+ V + N+ GS T++ R P GP + ++ S+ + W+ P
Sbjct: 19152 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP--GPIRIDEVSC--DSITISWNP-P 19206
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV--EGNSSRSAQLTGLGKYVLYEVQVLAFTRI 1282
E D + Y V KE S T W + + + S ++ L Y+ +V A R
Sbjct: 19207 EYDGGCQISNYIVEKKETTSTT----WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19262
Query: 1283 GDGSPSHPP-ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL 1340
G S S ++ PGPP +++ + WQ P G ++ Y + ++
Sbjct: 19263 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19322
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + ++L Q +GL +Y +R+ A+ G G+ +++ RD
Sbjct: 19323 RSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPC 19380
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP +P V ++ +SV L W +P DG + + Y ++ RELP GRW L + +
Sbjct: 19381 DPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW-LKCNYTNIQET 19437
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
F V L Y+FRV A N SE SES + D P + + ++
Sbjct: 19438 YFEVTELTEDQRYEFRVFARN--AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIV 19495
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
++ KIN + G R ++ G + + ++ ++++ R
Sbjct: 19496 VKAGEVL--KINADIAG---RPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRR 19550
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1639
QY L N + ++ GP + P E+ +G TA +
Sbjct: 19551 DTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEI----------------NGLTAEK 19594
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
++W P D DI Y + + + +L + L S K+ L Y+
Sbjct: 19595 CSLSWGRPQEDG-GADIDYYIVE--KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFR 19651
Query: 1700 VAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEG 1756
V N G G S + PS P+S++ + +T S+ + W P+ G + G
Sbjct: 19652 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19711
Query: 1757 YRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT---FTYGPEIE 1813
Y + + + + V V+ K L +K L EG Y +R+ A+ + E
Sbjct: 19712 YIIERREKNSL----RWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETS 19767
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDI 1871
+ P PP P IV + I I W G PIT Y +E + SD+ W
Sbjct: 19768 PLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKT 19827
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS--QSVPAQKANPFYE 1928
I+ + + YT S L G Y FRV +VN G PS S Q ++ P ++
Sbjct: 19828 SIQSL--RGTEYTISG--LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD 19882
Score = 211 bits (538), Expect = 5e-54
Identities = 373/1635 (22%), Positives = 612/1635 (37%), Gaps = 185/1635 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQ-----TSTYLAVTSIAPNITRGPLDS---- 411
+D ++ L DT F+ A+NAAG + T AP + LD+
Sbjct: 22692 SDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAP--PKAELDARLHG 22749
Query: 412 ---TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHIS 468
T+ G +VL G P P I W KG++ L ++T + + +I S
Sbjct: 22750 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG-KRATAVIKFCDRS 22808
Query: 469 DAGTYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGT--QASMVCGVT 520
D+G YT N+ G S + V + +++ Q++ + + Q +T
Sbjct: 22809 DSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEIT 22868
Query: 521 H---DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG-- 575
H + R T R W T S+ RL +N Y RV +
Sbjct: 22869 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNE-------------YIFRVRAVNKY 22915
Query: 576 --GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEM 629
G S + R +P P P + E I + WTKP DG + + Y+++
Sbjct: 22916 GPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH--IIIQWTKPESDGGNEISNYLVDK 22973
Query: 630 SENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE 688
E + WT + T + V L+ YQFR+ AVN G + S+ + +S E
Sbjct: 22974 REKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP 23033
Query: 689 PPT-APPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
T PP T SI + W P I+ GY++ Y+ T+A
Sbjct: 23034 SYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIV-GYVLEMQEKDTDQWYRVH--TNA 23090
Query: 748 DVNN--LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNS 805
+ N + DL + Y VAA N G+ YS + E +P + + +
Sbjct: 23091 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 23150
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
TIR A ++ + +I W + + + S+ + + K
Sbjct: 23151 VTIRA--GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-----VDKVN 23203
Query: 866 EYFTSVLCFTTPGD-GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y G +S LV+ + D PGP + E+ S+ ++W+ P G
Sbjct: 23204 RYDAGKYTIEAENQSGKKSATVLVKVY-DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23262
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + E + + TL YR++GL T Y V G G+ T
Sbjct: 23263 PVNNYIVEKREAAMRAFKTVTTKCSKTL-YRISGLVEGTMYYFRVLPENIYGIGE-PCET 23320
Query: 984 ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEA-QVGVVGEGEEW 1041
+ + E+P P L + ++ +VTL + +P YDG + ++ +++EA + G E W
Sbjct: 23321 SDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT----ERW 23376
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQTLQAPPDMA 1099
+ + L +P V LN Y FR+R N G S P + + +Q L+ P +
Sbjct: 23377 MKVVTL--KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTID 23434
Query: 1100 PANVSLRTAS-------ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS---DGHGKTLS 1149
+ + +T E + + P P + G K++ S + H K
Sbjct: 23435 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWF----FAGSKLRESERVTVETHTKVAK 23490
Query: 1150 HVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
+ R+ TI D E+T ++ N G+ + V+ + P +GP + +
Sbjct: 23491 LTI-----RETTIRDTGEYT-----LELKNVTGTTSETIKVIILDKPG-PPTGPIKIDEI 23539
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGK 1268
TS + + W E PE D + GY V E+ +P + V + +RS + T L +
Sbjct: 23540 DATS--ITISW-EPPELDGGAPLSGYVV---EQRDAHRPGWLPVSESVTRSTFKFTRLTE 23593
Query: 1269 YVLYEVQVLAFTRIGDGSPSHPPILE-RTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAP 1327
Y +V A R G GS ++E R+ +PGPP + +V + L W PP
Sbjct: 23594 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23653
Query: 1328 NGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA 1387
G + I R V + + +Y +TGL Y R+TA +G G+ +
Sbjct: 23654 GGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPS 23713
Query: 1388 EAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPS 1444
+V + P P P V D SV L+W P +G S V Y I+ +++
Sbjct: 23714 RPSKPIVAMDPIAPPGKPQNPRV--TDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ 23771
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEA 1504
W + + + + + L Y+FRV A N G E P E
Sbjct: 23772 HEWTKCNTTPT-KIREYTLTHLPQGAEYRFRVLACNAGGPGE--------------PAEV 23816
Query: 1505 PTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-----FTLRGINN 1559
P + VT ++ + D+ RY+E ++ G ++G
Sbjct: 23817 PGTVKVTE------MLEYPDYELDE----------RYQEGIFVRQGGVIRLTIPIKGKPF 23860
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
P W + S R + S T EL R Y+ V E + V++
Sbjct: 23861 PICKWTKEGQDISKRAMIATSETHTELVIKEADRG---DSGTYDLVLENKCG-KKAVYIK 23916
Query: 1620 EAV---PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG---NLTE 1673
V P + + + V+W PP D DI GY + E + +
Sbjct: 23917 VRVIGSPNSPEGPLEYDDIQVRSVRVSWR-PPADDGGADILGYILERREVPKAAWYTIDS 23975
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQAAPSAPSS- 1729
RV+ S+ +K L Y V+A N G P +T P PS+
Sbjct: 23976 RVR-----GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP 24030
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ ++T +SV++SW P+ G + GY + + S K V + + V
Sbjct: 24031 PEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETS----TDKWVRHNKTQITTTMYTV 24086
Query: 1789 KDLAEGVTYRFRIRAKT----FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHW 1844
L Y+FRI A+ P E V P + P + I+ ++ + W
Sbjct: 24087 TGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQW 24146
Query: 1845 SSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAV 1903
+ G I Y +E R S + W K + + F++ L Y+FRV A
Sbjct: 24147 EKPECDGGKEILGYWVEYRQSGDSAWK---KSNKERIKDKQFTIGGLLEATEYEFRVFAE 24203
Query: 1904 NDYGFGTPSSPSQSV 1918
N+ G P + S+
Sbjct: 24204 NETGLSRPRRTAMSI 24218
Score = 211 bits (537), Expect = 6e-54
Identities = 408/1878 (21%), Positives = 683/1878 (36%), Gaps = 218/1878 (11%)
Query: 136 RIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGD 192
R+ P+P +TW ++G+ + R+ + + L I V D G+Y + A KN
Sbjct: 11626 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISA---KNSS 11682
Query: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKL 247
+ V + GP + T + T + G SE+T V +P K
Sbjct: 11683 GHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQK- 11741
Query: 248 HIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP 307
W S SD +RL N ++ Y+ A + P++ + + P
Sbjct: 11742 --GW-------SIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINP 11792
Query: 308 PQFVKEPER-HITAEMEKVVDIPCQAKGVP--PPSITWYKDAAVVEVEKLTRFRQRN--D 362
EPE HI + + V + + P+++++ + + + R + + +
Sbjct: 11793 IDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKE 11852
Query: 363 GGLQISGLVPDDTGMFQCFARNAAGE---VQTSTYLAVTSIAPNITRGPLDS--TVIDGM 417
+ V + F+ +N GE V+T + + + L TV G
Sbjct: 11853 THYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11912
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRF---TPLESGSLLISPTHISDAGTYT 474
++ L G P P + W K + A+ + PR T +S ++ SD G Y
Sbjct: 11913 TIRLEAGVRGKPFPEVAWTKDKD--ATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11970
Query: 475 CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPR---------- 524
ATN+ G A A + V + KP +++ +S C V DP
Sbjct: 11971 VTATNTAGSFVAYATVNV-----LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQN 12025
Query: 525 ------VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGND 578
T R +W AT+ T RL IGT +
Sbjct: 12026 YILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGT-------GPPTE 12078
Query: 579 SRSAHLRVR-QLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP- 635
S+ + + P P+ P T V + + + W P +DG + Y LE E ++
Sbjct: 12079 SKPVIAKTKYDKPGRPDPPEVT--KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 12136
Query: 636 WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--PEEPPTAP 693
W + S P+ + V+ L+P YQFR+ A N++G G+ S + V P EPP P
Sbjct: 12137 WVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP-GP 12194
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII---------------RYCLAGLPVG 738
P N T SI + W P I+ GY++ + C A +
Sbjct: 12195 PTNFRVVDTTKHSITLGWGKPVYDGGAPII-GYVVEMRPKIADASPDEGWKRCNAAAQLV 12253
Query: 739 YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV 798
+ +T D N YE V A N G+G +++ E ++ + P +
Sbjct: 12254 RKEFTVTSLDENQ----------EYEFRVCAQNQVGIG-RPAELKE-AIKPKEILEPPEI 12301
Query: 799 HAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFV 858
+A+ + P F + + W + V R D +
Sbjct: 12302 DLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNV----VRKGQVDLVDTMAF 12357
Query: 859 SGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP 918
+ T + T + D PGPV L S++ TS VSW P
Sbjct: 12358 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPP 12417
Query: 919 GEKNGI-LTGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
G +T Y + E +R T + VT + + + VT L Y V A+ G
Sbjct: 12418 ENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS--FHVTNLVPGNEYYFRVTAVNEYGP 12475
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLV--EAQ 1031
G + + + P P PP L ++ + S TL + P DG I ++ +
Sbjct: 12476 GVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREE 12535
Query: 1032 VGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS---RK 1088
E+ ++ L S+ V L Y FR+ N VG S P +
Sbjct: 12536 EQPADRWTEYSVVKDL-------SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12588
Query: 1089 IQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
+ L P + P ++++ + + E G P K+ + + T
Sbjct: 12589 KEQLLPPKILMPEQITIKAGKKLRI--------EAHVYGKPHPT---CKWKKGEDEVVTS 12637
Query: 1149 SHVVQDRVERD--YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNV 1206
SH+ + + I+D+ + A N+ G+ VV P P ++
Sbjct: 12638 SHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG-PPQPPFDI 12696
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL-----VEGNSSRSA 1261
S + + S+ W +P D + Y V + D W+ V S R
Sbjct: 12697 SDIDADACSL--SW-HIPLEDGGSNITNYIV----EKCDVSRGDWVTALASVTKTSCRVG 12749
Query: 1262 QLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLI 1320
+L +Y+ +V A R G P + P ++ + VP P +V + +
Sbjct: 12750 KLIPGQEYIF---RVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVA 12806
Query: 1321 WQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
W P + G I+ Y I + + + L S +Y GL Y FRI A
Sbjct: 12807 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRST-EYPCAGLVEGLEYSFRIYALN 12865
Query: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQ 1438
+ G ++ T R PP +P V DV +V L W P DG S + Y ++
Sbjct: 12866 KAGSSPPSKPTEYVT-ARMPVDPPGKPEV--IDVTKSTVSLIWARPKHDGGSKIIGYFVE 12922
Query: 1439 TRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTL 1497
+LP +W ++A + L+ Y+FR A + S SE S+ +T L
Sbjct: 12923 ACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL 12982
Query: 1498 QAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
+V P SV ++ + N L T+ G
Sbjct: 12983 AE---------NVPPRIDLSVAMKSLLTVKAGTNVCL----------------DATVFGK 13017
Query: 1558 NNPGATWAE----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPP 1613
P +W + L ++ + +L EL ++N+ + ++ N+ G ++
Sbjct: 13018 PMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13077
Query: 1614 QEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE 1673
+V P +V ++ + + ++WE PPL+ +I Y + E R N +
Sbjct: 13078 LKVL----DKPGPPASVKINKMYSDRAMLSWE-PPLEDGGSEITNYIVDKRETSRPNWAQ 13132
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFN--AAGDGPRSTPTQGQTQQAAPSAPSSVK 1731
T+ + SV+ K + G+ Y + A N GD + P + P
Sbjct: 13133 VSATVPITSCSVE-KLIEGH-EYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 13190
Query: 1732 FSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD 1790
S +T + VSW+ P G + GY L V+ V+ K LK
Sbjct: 13191 ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VNRKPIIERTLKATG 13246
Query: 1791 LAEGVTYRFRIRAKTFTYGPEIEANVTTG----PGEGAPGPPGVPIIVRYS-SAIAIHWS 1845
L EG Y FR+ A GP ++ + + PGPP P + + S++++ W
Sbjct: 13247 LQEGTEYEFRVTAIN-KAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW- 13304
Query: 1846 SGDP---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
G P G PI Y++E + +D W + ++P+ + F + L Y FRV A
Sbjct: 13305 -GKPAYDGGSPIIGYLVEVKRADSDNW--VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYA 13361
Query: 1903 VNDYGFGTPSS-PSQSVP 1919
VN G+ PS P + P
Sbjct: 13362 VNKIGYSDPSDVPDKHYP 13379
Score = 211 bits (537), Expect = 6e-54
Identities = 342/1451 (23%), Positives = 555/1451 (38%), Gaps = 168/1451 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W K G + +I S L I D G YT + G + V +
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14167
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAP-WTVLLASVDPKA 647
P P PV +S V LTWT P DG SP+ YILE E + WTV+ S D ++
Sbjct: 14168 P-GPPGPVE-ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVV--SEDIQS 14223
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
L+ Y FR+ AVN GKG+ + + P PP+ S T +
Sbjct: 14224 CRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTA 14283
Query: 708 MIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKN-ITDADVNNLLLEDLIIWTNYEIE 766
+ W+ P + + I ++ R L K ++D L++ + YE
Sbjct: 14284 TVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQE---GSTYEFR 14340
Query: 767 VAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824
V+A N AG+G S ++ P PP N H T + W P +
Sbjct: 14341 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH------YD 14394
Query: 825 QGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG--FVSGLKKFTEYFTSVLCFTTPGDGPR 882
G ++ + E ++ + ++ + V L+ +Y + G G
Sbjct: 14395 GGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEP 14454
Query: 883 STPQLVRTHEDVPGPVGHLSFSEILDT-------SLKVSWQEPGEKNGILTGYRISWEEY 935
+ V E P L +E+ T S+++ G +T + +
Sbjct: 14455 AVIPDVEIVEREMAPDFELD-AELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK 14513
Query: 936 NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGP 995
NR N T + + T TIE A K G V+ + + PGP
Sbjct: 14514 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPA--GKKSGFVNVRVLDT------PGP 14565
Query: 996 PTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDAR 1054
NL ++I SVTL + P DG + I+ ++VE + + +
Sbjct: 14566 VLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS------YSTATTKCHKC 14619
Query: 1055 SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLW 1114
+ +V L+ Y FR+ N G P++ + ++ +AP P ++++ +++++
Sbjct: 14620 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSP--PDSLNIMDITKSTVS 14677
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
L W P+ +++G + GY I+ R T V+ + + +L E EY Q
Sbjct: 14678 LAW---PKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL---ECVVRNLTEGEEYTFQ 14731
Query: 1175 VQAFNAIG-SGPW-SQTVVGRTRESVPS---SGPTNVSALATTSSSMLVRWSEVPEADRN 1229
V A N+ G S P S+ V+ + + +P G +A ++ V E+P R
Sbjct: 14732 VMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV---EIPVLGRP 14788
Query: 1230 GLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFT------RIG 1283
+ +K K + V ++ ++ + + + V + T +G
Sbjct: 14789 KPTVTWK-----KGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVG 14843
Query: 1284 DGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342
D ++ + D+PGPP G I F EV + V W PP G+ ++ + T
Sbjct: 14844 D-------VITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 14896
Query: 1343 TTANTATVEVLAPSARQ-YTATGLKPESVYLFRITAQTRKGWGEA-AEALVVTTEKRDRP 1400
+ T VE+ R Y AT L Y FR+ AQ R G G A +V P
Sbjct: 14897 DS--TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVP 14954
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVSHNA 1458
PP P V V S+ +SW EP SDG SP+ Y ++ +E W + A V N
Sbjct: 14955 GPPGTPQVTA--VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 15012
Query: 1459 --SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTT 1515
SS + D + +Y+FRV A N G S+ S+ SE + L P P L++T HT
Sbjct: 15013 FKSSGLTDGI----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTV 15068
Query: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
T ++W P + G GF+I + + + P W + N
Sbjct: 15069 T---LKWAKP---EYTG---GFKIT----------SYIVEKRDLPNGRWLKA-------N 15102
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGPSSPPQEVFVGEAVPTAAPR----- 1628
S ++ + L + YE R+ NA G PS P + + V AP+
Sbjct: 15103 FSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDV 15160
Query: 1629 ----NVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
V++ A +L DV+ PPP + D + G +K +
Sbjct: 15161 KFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD--------GKELEGTAKLEIKIADFST 15212
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
N V K+ T + ++ A N G + + P P +V +E+T+ +
Sbjct: 15213 NLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAV--TEVTSEKCVL 15269
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLW-LKVKDLAEGVTYRFRI 1801
SW P G + +V + S++ +V + LKV L +G Y FR+
Sbjct: 15270 SWFPPLDDGGAKIDHYIVQKR-----ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRV 15324
Query: 1802 RA-KTFTYGPEIEANVTTGPGE-GAPGPPGVPIIVRYSS-AIAIHWSSGDP-GKGPITRY 1857
A + G +E+ G P PP P + + ++ + W D G I Y
Sbjct: 15325 MAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15384
Query: 1858 VIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
++E R W IK K ++ + + L G Y+FR++A N G PS S
Sbjct: 15385 IVERRDKAGQRW---IKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-- 15439
Query: 1918 VPAQKANPFYE 1928
PFY+
Sbjct: 15440 -------PFYK 15443
Score = 211 bits (537), Expect = 6e-54
Identities = 438/1934 (22%), Positives = 700/1934 (36%), Gaps = 355/1934 (18%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY----YVQAVNDKNGDNKTS 196
P P+VTW +D + + I T TL+I+ P+ RY +V + + G K S
Sbjct: 14499 PAPEVTWTKDNINLKNRANIENTESFTLLII----PECNRYDTGKFVMTIENPAG--KKS 14552
Query: 197 QPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKLHIIW 251
+ + V + GP + PT I T ++ G S +T +I+
Sbjct: 14553 GFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT------------NYIVE 14600
Query: 252 KKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFV 311
K++ S + TG G CE R + G EP V
Sbjct: 14601 KREATRKSYSTATTKCHKCTYKVTGLSEG---CEYFFRVMAENEYGIGEPTETTEP---V 14654
Query: 312 KEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLV 371
K E + ++DI S+ W K ++DGG +I+G V
Sbjct: 14655 KASEAPSPPDSLNIMDITKST-----VSLAWPK--------------PKHDGGSKITGYV 14695
Query: 372 PD-------------DTGMFQCFARN-AAGEVQTSTYLAVTS------------------ 399
+ +C RN GE T +AV S
Sbjct: 14696 IEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14755
Query: 400 IAPNI-TRGPLDSTVI--DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLE 456
+ P + RG VI G ++ + G P+P +TW+KG++IL Q F
Sbjct: 14756 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK--QTQRVNFETTA 14813
Query: 457 SGSLL-ISPTHISDAGTYTCLATNSRG----------------------VDEASADLVVW 493
+ ++L I+ SD+G Y A N G DE S+D V +
Sbjct: 14814 TSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 14873
Query: 494 ARTRITKPPQDQS-------VIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
+ PP++ V++ Q V V IR ++ T G E R+
Sbjct: 14874 S----WDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-IRTTYKATRLTTGLEYQFRV 14928
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
+ + T + + Y +V P P P T V +
Sbjct: 14929 KAQNRYGVGPGITSACIVANYPFKV------------------PGPPGTPQVT--AVTKD 14968
Query: 607 AINLTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFR 664
++ ++W +P DG SP++ Y +E E N W + ++ P GL +Y+FR
Sbjct: 14969 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP-GNIFKSSGLTDGIAYEFR 15027
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-L 723
+ A N GK + SK +E + + P PP + T ++ ++W P + G +
Sbjct: 15028 VIAENMAGKSKPSKPSEPMLALD--PIDPPGKPVPLNITRHTVTLKWAKP--EYTGGFKI 15083
Query: 724 KGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782
YI+ LP G K N ++ N + L YE V A N+AG
Sbjct: 15084 TSYIVE--KRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG-------- 15133
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
PP +E +++ T R AP + L A E + E
Sbjct: 15134 --------AISPP----SEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 15181
Query: 843 VTARPNFQDSIHVGFVSGLK----KFTEYFTSVL----------CFTTPGDGPRSTPQLV 888
P + S + G K ++ T+++ +T P + +
Sbjct: 15182 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHI 15241
Query: 889 RTHE--DVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTH 944
+ D PG P G L+ +E+ +SW P + G + Y + E +R
Sbjct: 15242 FNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA 15301
Query: 945 YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISN 1003
VT + +VT L Y V A+ G G+ + + + + P P PP N ++
Sbjct: 15302 SEVQVT-KLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTT 15360
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I S+ + + P DG + I ++VE + G+ W+ ++ D R +V L
Sbjct: 15361 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKA---GQRWIKCNK-KTLTDLR-YKVSGLT 15415
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPS---RKIQTLQAPPDMAPANVSLRTASETSLWLRW-M 1118
Y FR+ N G S PS S + T+ P P N + S +S+ + W
Sbjct: 15416 EGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG--PPGNPRVLDTSRSSISIAWNK 15473
Query: 1119 PLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAF 1178
P+ Y+G E GY ++ + + + YTI L E EY++++ A
Sbjct: 15474 PI----YDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAM 15529
Query: 1179 NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR---------------WSEV 1223
N+ G G +V T ++ P + A + +R EV
Sbjct: 15530 NSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEV 15587
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
A +G + + K T L+ GN +R GKY+L +
Sbjct: 15588 KWARDHG-----ESLDKASIESTSSYTLLIVGNVNRFDS----GKYIL---------TVE 15629
Query: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTT 1343
+ S S + + D PGPP + EV TSV L W PP G + I + +T
Sbjct: 15630 NSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 15689
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPP 1403
+TV + L+ Y FR+ A+ G G AE + + +RP PP
Sbjct: 15690 RKAYSTVATNCHKT-SWKVDQLQEGCSYYFRVLAENEYGIGLPAET-AESVKASERPLPP 15747
Query: 1404 SRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462
+ + DV SV LSWE P DG S + Y ++ + S +WA + +
Sbjct: 15748 GK--ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA---TCATVKVTEAT 15802
Query: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRW 1522
+ L Y FRV A N+ G S+ P LSV P ++I
Sbjct: 15803 ITGLIQGEEYSFRVSAQNEKGISD------------------PRQLSV-PVIAKDLVI-- 15841
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATW------AELTSM 1570
PPA F++ + + L G L+ G P TW + T+
Sbjct: 15842 -PPA----------FKLLFN--TFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTR 15888
Query: 1571 YSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV 1630
+ + SL + Y ++++ N+ GE + V PT V
Sbjct: 15889 VNAESTENNSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIVLDKPGPPTGP---V 15943
Query: 1631 VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNL 1690
+ TA + ++W PP D I Y + + T ++ + +A ++K L
Sbjct: 15944 KMDEVTADSITLSWGPPKYDG-GSSINNYIVE--KRDTSTTTWQIVSATVARTTIKACRL 16000
Query: 1691 TGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
Y +AA N G S PT Q P P + + + S+ V W
Sbjct: 16001 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWN--- 16057
Query: 1749 FPNGILEGYRLVYEPCSPVDGVSKIVTVDV---KGNSPLWLKVK------------DLAE 1793
EP S DG S+++ + + NS LW+K+ L E
Sbjct: 16058 -------------EPIS--DGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 16102
Query: 1794 GVTYRFRIRAKTFT----YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD- 1848
GV Y FR+ A+ E V P + PG P I+ R +++ + W
Sbjct: 16103 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCD-PPGRPEAIIVTR--NSVTLQWKKPTY 16159
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG- 1907
G IT Y++E + EG W +K + F + L Y+FRVIA N G
Sbjct: 16160 DGGSKITGYIVEKKELPEGRW---MKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 16216
Query: 1908 FGTPSSPSQSVPAQ 1921
F PS + ++ A+
Sbjct: 16217 FSEPSESTGAITAR 16230
Score = 210 bits (535), Expect = 1e-53
Identities = 345/1488 (23%), Positives = 556/1488 (37%), Gaps = 155/1488 (10%)
Query: 506 SVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LDRNGSLHISQTWSGDI 564
+V GT+ + VT P I W K L + I + + ++ I + D
Sbjct: 7396 TVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7453
Query: 565 GTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLI 623
GTY ++ G + + V P P ++ V + LTW P D G S +
Sbjct: 7454 GTYIIEAVNVCGRATAVVEVNVLDKPGPPA--AFDITDVTNESCLLTWNPPRDDGGSKIT 7511
Query: 624 RYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
Y++E ++ W L ++V K T+ L+P + Y FR+ A N G G+ + +
Sbjct: 7512 NYVVERRATDSEVWHKLSSTV--KDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 7569
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
+ + P PP + S T ++ + W P + + I GY + +
Sbjct: 7570 TAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT-GYWVERLDPDTDKWVRCN 7628
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHA 800
+ D ++ L Y V A N AG G S ++ P PPG
Sbjct: 7629 KMPVKDTT-YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTV 7687
Query: 801 EATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ T++R W P I + Y + + +E V + P Q + G
Sbjct: 7688 KDVGKTSVRLNWTKPEHDGGAKI-ESYVIEMLKTGTDEWVRVAEGVPTTQH-----LLPG 7741
Query: 861 LKKFTEYFTSVLCFTTPGDGPRSTPQ---LVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G+ S P L R P P L I + + W
Sbjct: 7742 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 7801
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +T Y + + R + T + VT LT + Y VAA + GQ
Sbjct: 7802 PEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDT-KCTVTPLTEGSLYVFRVAAENAIGQ 7860
Query: 977 GQVSA--STISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVG 1033
+ ++ + PGPP L + ++ R V L++ P DG I R+++E +
Sbjct: 7861 SDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKER 7920
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
+ G W+ + + PD + V D+ T F++R N G PS+P+ +I +++
Sbjct: 7921 L---GTRWVKAGKTAG-PDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT-EILSIE 7974
Query: 1094 AP--PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKI--------KYSRSDG 1143
P P P ++ + A + + W P E NG +GY + K+ R +
Sbjct: 7975 DPTSPPSPPLDLHVTDAGRKHIAIAWKP---PEKNGGSPIIGYHVEMCPVGTEKWMRVNS 8031
Query: 1144 HG-KTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG---SGPWSQTVVGRTRESVP 1199
K L V++ V D EY ++V+A NAIG S+ VV + + P
Sbjct: 8032 RPIKDLKFKVEEGVVPD---------KEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKP 8082
Query: 1200 SSG--PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
+ ++ + S+ V + VP V +K + K SD L N
Sbjct: 8083 TIDLETHDIIVIEGEKLSIPVPFRAVPVPT----VSWHKDGKEVKASDR-----LTMKND 8133
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFT---RIGDGSPSHPPILERTLDDVPGPPMGILFPEVRT 1314
SA L + K V + + T ++G + S + + +PGP I ++
Sbjct: 8134 HISAHLE-VPKSVRADAGIYTITLENKLGSATAS----INVKVIGLPGPCKDIKASDITK 8188
Query: 1315 TSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFR 1374
+S +L W+PP G + + + R V + + +T L P Y FR
Sbjct: 8189 SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFR 8247
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSWEPGS-DGLSPV 1432
+ A + G GE E L +D QPP P+ V+ + A ++ ++W+P DG S +
Sbjct: 8248 VKAVNKVGGGEYIE-LKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8306
Query: 1433 RYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE 1492
Y I+ RW + + ++ L+ Y+FRV+A N G SE S +
Sbjct: 8307 MGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATP 8365
Query: 1493 SLTTLQAAPDEAPTIL-------------------SVTPHTTTSVLIRWQP------PAE 1527
T P +AP ++ S +P+ T I W P E
Sbjct: 8366 P--TKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPT----ITWIKDENVIVPEE 8419
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
K L +R R+ + F L LT S+ N + D
Sbjct: 8420 IKKRAAPL---VRRRKGEVQEEEPFVL-----------PLTQRLSIDNSKKGESQLRVRD 8465
Query: 1588 NLNK-HRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEP 1646
+L H Y I++ + + + P + V P N V T + WEP
Sbjct: 8466 SLRPDHGLYMIKVENDHGIAKAPCT------VSVLDTPGPPINFVFEDIRKTSVLCKWEP 8519
Query: 1647 PPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAA 1706
P LD +I Y + + + + V T L + L Y+ V A N
Sbjct: 8520 P-LDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8578
Query: 1707 GDGPR--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
G GP S P + P AP ++T+ S+ V W P+ + GY L
Sbjct: 8579 GPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREV 8638
Query: 1765 SPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTT 1818
+ V+K + +K N V L EG+TY FR+ A+ + P +
Sbjct: 8639 NSTHWSRVNKSLLNALKAN------VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAH 8692
Query: 1819 GPGEGAPGPPGVPIIVRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIP 1877
P PGPP + S+ I + W G G I Y ++ + W + +
Sbjct: 8693 DP-ISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI 8751
Query: 1878 KEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
K V YT ++ G Y RV AVN G G P A+ P
Sbjct: 8752 K-VRQYTVKE--IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP 8796
Score = 207 bits (527), Expect = 9e-53
Identities = 337/1448 (23%), Positives = 550/1448 (37%), Gaps = 155/1448 (10%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGGNDSRS 581
P+ T+ W KDG TL + + + SL I + D+GTY V ++ G+ +
Sbjct: 19117 PQATVN--WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 19174
Query: 582 AHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVL 639
+ V P P P+ + V +I ++W P +DG + YI+E E + W ++
Sbjct: 19175 ITIIVLDRP-GPPGPIR-IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19232
Query: 640 LASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIA 699
+V TS+ + L YQFR+CA N GK +S+ + V+ P PP
Sbjct: 19233 SQAV--ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV 19290
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
T ++++ WQ P + ++ GY + Y + + I AD + + L
Sbjct: 19291 VHATKSTMLVTWQVPVNDGGSRVI-GYHLEYKERSSILWSKANKILIADTQ-MKVSGLDE 19348
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
YE V A N AG+G SK E P PPG ++ W+ P
Sbjct: 19349 GLMYEYRVYAENIAGIGK-CSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPH--- 19404
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEY----FTSVLCF 874
+ G K+ + E+ E + N+ + F V+ L + Y F
Sbjct: 19405 ---YDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAAD 19461
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS----LKVSWQEPGEKNGILTGYRI 930
+ + P +V+ + P + + F +++ LK++ G +++ +
Sbjct: 19462 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19521
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPP 990
E R T + + L + Y + + + V+ +
Sbjct: 19522 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK---- 19577
Query: 991 ELPGPPTN-LGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP L I+ + +L + RP DG I ++VE + W +
Sbjct: 19578 --PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET---SHLAWTICE--- 19629
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP--SQPSRKIQTLQAPPDMAPANVSLR 1106
E S +V L Y FR+ VN G P S + + P P ++ +
Sbjct: 19630 GELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEIT 19687
Query: 1107 TASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV-VQDRVERDYTIED- 1164
+ ++ S+ L W E +G E GY I+ + +L V V + D ++
Sbjct: 19688 SVTKESMTLCWS---RPESDGGSEISGYIIERREKN----SLRWVRVNKKPVYDLRVKST 19740
Query: 1165 -LEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESV----PSSGPTNVSALATTSSSMLV 1218
L E EY +V A NA G S P + + R + V P S P V + TT + +
Sbjct: 19741 GLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTT---ITI 19797
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLT--GLGKYVLYEVQV 1276
W + P D + GY V YK+ D DT W S R + T GL Y +V
Sbjct: 19798 AWVK-PLFDGGAPITGYTVEYKKSD-DTD---WKTSIQSLRGTEYTISGLTTGAEYVFRV 19852
Query: 1277 LAFTRIGDGSPSH---PPILERTLDDVPGPPMGILFPEVRTTSV---RLIWQPPAAPNGI 1330
+ ++G PS P I + ++ P+ + E+R T + + G
Sbjct: 19853 KSVNKVGASDPSDSSDPQIAKEREEE----PLFDIDSEMRKTLIVKAGASFTMTVPFRGR 19908
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ + + +T A V+ S T + +T Q +A +L
Sbjct: 19909 PVPNVLWSKPDTDLRTRAYVDT-TDSRTSLTIENANRNDSGKYTLTIQNVL----SAASL 19963
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWAL 1449
+ + D P PP+ VQ DV S +LSW+ P +DG +PV+ Y I+ RE W
Sbjct: 19964 TLVVKVLDTPGPPTNITVQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWV- 20020
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
S + + N S+ V L+ Y FRV N+ G +E E + + P L
Sbjct: 20021 -SVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKP--SPPEKLG 20077
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + SV + W P D G RI + + + + W +
Sbjct: 20078 VTSISKDSVSLTWLKPEHDG------GSRIVH----------YVVEALEKGQKNWVKCAV 20121
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------P 1623
S T + + L ++ Y R+ N G S P+E+ + + P
Sbjct: 20122 AKS---------THHVVSGLRENSEYFFRVFAENQAG---LSDPRELLLPVLIKEQLEPP 20169
Query: 1624 TAAPRN-----VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
+N V V + ++D+ PL G + T R T
Sbjct: 20170 EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL--------KATMRFNTE 20221
Query: 1679 FLAEN-SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737
AEN ++ LK A + A N++G + P+ P V S++T
Sbjct: 20222 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP--VVISDITE 20279
Query: 1738 TSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVT 1796
SV + WE P++ G + Y L+ S TV + +KV L G
Sbjct: 20280 ESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV-----ARTMMKVMKLTTGEE 20334
Query: 1797 YRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKG 1852
Y+FRI+A+ F I+ A VT PGPP P + + +I + W G
Sbjct: 20335 YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGS 20394
Query: 1853 PITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ Y +E + + LW K + + + F + + G+ Y+FRV A N G G PS
Sbjct: 20395 AVVGYHLEMKDRNSILWQKANKLV---IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPS 20451
Query: 1913 SPSQSVPA 1920
PS+ V A
Sbjct: 20452 HPSEPVLA 20459
Score = 207 bits (526), Expect = 1e-52
Identities = 333/1443 (23%), Positives = 538/1443 (37%), Gaps = 164/1443 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W DG+ + T+ H + D S L I D G Y V +A G+ + + HL V +
Sbjct: 11239 WTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDV 11298
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P+ L + ++W P D G SP+I YI+E + +++S K T
Sbjct: 11299 PGPPTGPINILDVTPEH-MTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 11356
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ + L Y FR+ A N +G G T V+ + P +PP + + T +
Sbjct: 11357 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT 11416
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVA 768
+ W P + I Y+ R + G V I D + L YE V
Sbjct: 11417 VSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADL---KFRVTGLYEGNTYEFRVF 11473
Query: 769 AYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG 826
A N AGL SS + P PP N + + T W P + G
Sbjct: 11474 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS------DGG 11527
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIH--VGFVSGLKKFTEYFTSVLCFTTPGDG-PRS 883
++ + E ++ T R N + I V GL + EY + G+G PR
Sbjct: 11528 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11587
Query: 884 TPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYR------ISWEEYNR 937
+ V + + H E+ T V G+ IL + I+W + +
Sbjct: 11588 LAESV-----IAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11642
Query: 938 TNTR-----VTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
R + LP V L+ + Y I + QG + + +
Sbjct: 11643 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVL------DR 11696
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
PGP NL ++N+ + T+ + P +G + I+ ++VE + + W ++ +++
Sbjct: 11697 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR---KPNQKGWSIV---ASDV 11750
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQ---PSRKIQTLQAPPDMAPANVSLRTA 1108
R ++ +L Y FR+ N VG P + P I + P + P N+ +
Sbjct: 11751 TKRLIKA-NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGE--PENLHIADK 11807
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLE 1166
+T ++L+W +Y+G ++ Y + + SD + ++ E Y ++
Sbjct: 11808 GKTFVYLKWR---RPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK---ETHYMVDRCV 11861
Query: 1167 EWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS-------SGPTNVSALATTSSSMLVR 1219
E Y +VQ N G W +T +E + SG V A T VR
Sbjct: 11862 ENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVR 11921
Query: 1220 WSEVPEA----DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQ 1275
PE D++ L K +F L + S GKYV
Sbjct: 11922 GKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDG------GKYV----- 11970
Query: 1276 VLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ 1335
V A G S + D PGP + +V + + W PP G +
Sbjct: 11971 VTATNTAG----SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 12026
Query: 1336 ITHRLNTTTA--NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VV 1392
I + T +T + VL P T T L + Y+FR+ A+ + G G E+ V+
Sbjct: 12027 ILEKCETKRMVWSTYSATVLTPGT---TVTRLIEGNEYIFRVRAENKIGTGPPTESKPVI 12083
Query: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWA-LH 1450
K D+P P P V + V + + W P DG + Y ++ +E S RW ++
Sbjct: 12084 AKTKYDKPGRPDPPEVTK--VSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN 12141
Query: 1451 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ-AAPDEAPTILS 1509
+++ V L P Y+FRVKA N+IG E S S + P PT
Sbjct: 12142 KSAIPERRMK--VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFR 12199
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
V T S+ + W P D ++G+ + R + + +P W +
Sbjct: 12200 VVDTTKHSITLGWGKPVYDG-GAPIIGYVVEMRPKIADA----------SPDEGWKRCNA 12248
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG------PSSPPQEVFVGEAVP 1623
+ ++ + +L++++ YE R+ N VG G + P+E+ +
Sbjct: 12249 AAQLVR------KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEID 12302
Query: 1624 TAAP--RNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL- 1678
A + V+V +L V P P + K+ R + V T+
Sbjct: 12303 LDASMRKLVIVRAGCPIRLFAIVRGRPAP------KVTWRKVGIDNVVRKGQVDLVDTMA 12356
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
FL + + Y+ +V+ A A R T P S +K S++T T
Sbjct: 12357 FLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDT--------PGPVSDLKVSDVTKT 12408
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYR 1798
S +VSW P+ G + +V E VT +VK S V +L G Y
Sbjct: 12409 SCHVSWAPPENDGGSQVTHYIV-EKREADRKTWSTVTPEVKKTS---FHVTNLVPGNEYY 12464
Query: 1799 FRIRAKTFTYGPEIEANV-----TTGPGEGAPGPPGVPIIVRYSSAIAIHW-----SSGD 1848
FR+ A YGP + +V + P P + + ++ + W G
Sbjct: 12465 FRVTAVN-EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGA 12523
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGF 1908
G IT Y E +P+D ++KD+ V+ LK G Y FRV A N G
Sbjct: 12524 KIDGYITSYREEEQPADRWTEYSVVKDLSLVVTG-------LKEGKKYKFRVAARNAVGV 12576
Query: 1909 GTP 1911
P
Sbjct: 12577 SLP 12579
Score = 204 bits (520), Expect = 6e-52
Identities = 375/1638 (22%), Positives = 639/1638 (39%), Gaps = 191/1638 (11%)
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAG---EVQTSTYLAVTS----IAPNITRGP--LDST 412
D +++GLV D F+ ARNAAG E ST A+T+ P I+ P D+
Sbjct: 16190 DTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTG-AITARDEVDPPRISMDPKYKDTI 16248
Query: 413 VID-GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
V+ G S + + G P P I W KG++ L S + +L + + SL + D+G
Sbjct: 16249 VVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAVRVDSG 16307
Query: 472 TYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQA---------------SMV 516
Y A N G + ++ V R PP+ VI G A S +
Sbjct: 16308 NYILKAKNVAGERSVTVNVKVLDR---PGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDI 16364
Query: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG- 575
+ R T R +W A + T S +++ G+ YT R+++
Sbjct: 16365 INYIVERRETSRLVWTVVDANVQTL-----------SCKVTKLLEGN--EYTFRIMAVNK 16411
Query: 576 ---GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILE 628
G S + + +P AP+ P T TV + ++ + W +P DG S ++ Y+LE
Sbjct: 16412 YGVGEPLESEPVVAKNPFVVPDAPKAPEVT--TVTKDSMIVVWERPASDGGSEILGYVLE 16469
Query: 629 MSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT--ERVSL 685
+ WT + + + V GL+ Y+FR+ A N G + S + ++
Sbjct: 16470 KRDKEGIRWTRCHKRLIGE-LRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 16528
Query: 686 PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
P P PP N T S+ + W P + G ++GYI+ C +
Sbjct: 16529 PIYKP-GPPNNPKVIDITRSSVFLSWSKP--IYDGGCEIQGYIVEKCDVSVGEWTMCTPP 16585
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T + N+ +E L+ Y + A N AG+G ++ ++ P ++ E
Sbjct: 16586 TGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRK 16645
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLK 862
IR F+ + + W E + ++ +F + L
Sbjct: 16646 IINIRA--GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV-------LD 16696
Query: 863 KFTEYFTSVLCFTTP-GDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEK 921
Y + T G +S VR D P P +L +EI S+ ++W+ P
Sbjct: 16697 NVNRYDSGKYTLTLENSSGTKSAFVTVRV-LDTPSPPVNLKVTEITKDSVSITWEPPLLD 16755
Query: 922 NGI-LTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ 978
G + Y + E R + VT+ N +++ L +Y V A G G
Sbjct: 16756 GGSKIKNYIVEKREATRKSYAAVVTNCHKN---SWKIDQLQEGCSYYFRVTAENEYGIG- 16811
Query: 979 VSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+ A T E+P PP + + ++ SV+L + +P +DG + I +++VE Q
Sbjct: 16812 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ---AKH 16868
Query: 1038 GEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQ 1093
E+W S +S++ + +L Y FR+ VN G S P + I + L
Sbjct: 16869 SEKW------SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV 16922
Query: 1094 APPDMAPA--NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV 1151
PD+ PA + S++ + + E+ +G P+ I +++ K + +
Sbjct: 16923 IEPDVKPAFSSYSVQVGQDLKI--------EVPISGRPKPT---ITWTKDGLPLKQTTRI 16971
Query: 1152 -VQDRVE-RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
V D ++ +I++ + + + N +G S +V + P GP +
Sbjct: 16972 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD-PPKGPVKFDDV 17030
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW-LVEGNSSRSA-QLTGLG 1267
++ S+ + W+ P G + ++ K DT W +V +R+ ++T L
Sbjct: 17031 --SAESITLSWN--PPLYTGGCQITNYIVQKR---DTTTTVWDVVSATVARTTLKVTKLK 17083
Query: 1268 KYVLYEVQVLAFTRIGDG-SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAA 1326
Y+ ++ A R G + PI+ + PGPP + S+ + W P
Sbjct: 17084 TGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVN 17143
Query: 1327 PNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGE 1385
G ++ Y + + + T + + Q+ A L+ Y FR+ A+ G G+
Sbjct: 17144 NGGSPVIGYHLERKERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGK 17202
Query: 1386 AAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTREL 1442
A++ V + D P P MV++ + + L W +P DG S + Y ++ R+L
Sbjct: 17203 ASKNSECYVARDPCDPPGTPEPIMVKRNE-----ITLQWTKPVYDGGSMITGYIVEKRDL 17257
Query: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
P GRW + ++ + + F V L Y+FRV A N G S+ S+S + A +
Sbjct: 17258 PDGRW-MKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG--AISKPSDSTGPITAKDE 17314
Query: 1503 EAPTILSVTPHTTTSVLIRWQPP--AEDKINGILLGFRIRYRELLYEGLRG-FTLRGINN 1559
+S+ P ++++ E ++G L E LRG +
Sbjct: 17315 VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP--------TIEWLRGDKEIEESAR 17366
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYEL--DNLNKHRRYEIRMSVYNAVG--EGPSSPPQE 1615
+ ++ +++ R QY L N+ + + + + V + G EGP
Sbjct: 17367 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP------ 17420
Query: 1616 VFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERV 1675
V V G T+ + +TW PPL DI Y + E R L V
Sbjct: 17421 --------------VQVTGVTSEKCSLTWS-PPLQDGGSDISHYVVEKRETSR--LAWTV 17463
Query: 1676 KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFS 1733
+ NS+K+ L Y+ + A N G G S P + P P S++ +
Sbjct: 17464 VASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 17523
Query: 1734 ELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLA 1792
+ S+ V W P G + GY + S + + + + + + L L+V L
Sbjct: 17524 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGI----RWIKCNKRRITDLRLRVTGLT 17579
Query: 1793 EGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPP-GVPIIVRYSSAIAIHWSSGD 1848
E Y FR+ A+ G A V + PGPP I+ ++I + W G
Sbjct: 17580 EDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW--GK 17637
Query: 1849 P---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
P G I YV+E +DE W I+ V+ + S L Y RV A+N
Sbjct: 17638 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISK--LTEHQEYKIRVCALNK 17695
Query: 1906 YGFGTPSS-PSQSVPAQK 1922
G G +S P P K
Sbjct: 17696 VGLGEATSVPGTVKPEDK 17713
Score = 202 bits (515), Expect = 2e-51
Identities = 431/1978 (21%), Positives = 725/1978 (36%), Gaps = 286/1978 (14%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGAL----------LQRQTEVQ--VAYMGSFEEGEK 120
E +Y +T L +R I RN +G + + R V V + + +G
Sbjct: 21605 ECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDG-- 21662
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT--LENTLVILSTVAPDA 178
+ GE+ I+A + P P+VTWF+DG +I + IT L +T + + D
Sbjct: 21663 -LIIKSGESLRIKA-LVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDH 21720
Query: 179 GRYYVQAVNDKNGDNKTSQPITL--TVENVGGPA-------------------DPIAPTI 217
Y + +G K + + T V GP D AP
Sbjct: 21721 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 21780
Query: 218 --IIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPT 275
II + TS +A + +C A + IKL +G +S N+ + P
Sbjct: 21781 HYIIEKRETSRLAWAL-IEDKCEAQSYTAIKLI-----NGNEYQFRVSAVNK-FGVGRPL 21833
Query: 276 GSDAGYYECEAVLRSSS---VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQA 332
SD + + + + PS + G +++ PE +E+++ + +
Sbjct: 21834 DSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA-----RPESDGGSEIQQYILERREK 21888
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
K S W K + + + TRF+ ++GL + F A NAAG S
Sbjct: 21889 K-----STRWVKVISKRPISE-TRFK--------VTGLTEGNEYEFHVMAENAAGVGPAS 21934
Query: 393 ------------------TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
T + VT + V DG ++
Sbjct: 21935 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21994
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGV-DEASADLVVW 493
W K + A V+ R+T ++ + + A N G D +
Sbjct: 21995 WHK---VNAEACVKT-RYT--------VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIK 22042
Query: 494 ARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR 547
A R+T P D Q+ + AS+ + + R T +W K + L +
Sbjct: 22043 AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT 22102
Query: 548 LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRA 607
D +L + D G YT V + G+ S + ++V P P P+ T V R +
Sbjct: 22103 -DSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTP-GPPGPI-TFKDVTRGS 22159
Query: 608 INLTWTKPF-DGNSPLIRYILEMSE-NNAPWTVLLASVDPKATS--VTVKGLVPARSYQF 663
L W P DG + + Y++E E + W V + K T V L Y F
Sbjct: 22160 ATLMWDAPLLDGGARIHHYVVEKREASRRSWQV----ISEKCTRQIFKVNDLAEGVPYYF 22215
Query: 664 RLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI- 722
R+ AVN+ G G+ + E + E+P APP+ + + S ++ W P H G
Sbjct: 22216 RVSAVNEYGVGEPYEMPEPIVATEQP--APPRRLDVVDTSKSSAVLAWLKP--DHDGGSR 22271
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG----VY 778
+ GY++ G + + +E L+ T YE V A N AG +
Sbjct: 22272 ITGYLLEMRQKGSDFWVEAGHTKQL---TFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 22328
Query: 779 SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG-------YKLIA 831
SS + + P + P A+ T T T A SP I+ G +KL
Sbjct: 22329 SSVIIK-----EPQIEPT---ADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEE 22380
Query: 832 WEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH 891
++ + V++ T + ++ + YF ++ T G S +V
Sbjct: 22381 MRLKETDRVSITTTKDRTTLTVKDSMRGDSGR---YFLTLE--NTAGVKTFSVTVVVIGR 22435
Query: 892 EDVPGPV-GHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNV 949
PGPV G + S + S +SW EP + G +T Y + E T ++ +
Sbjct: 22436 ---PGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKR 22492
Query: 950 TLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNIGPRS 1008
T + +VT LT Y+ V++ G + + ++ I + P P PT + ++ +
Sbjct: 22493 T-QIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANA 22551
Query: 1009 VTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
+++++ P +DG + I + VE + E L + + + +V L Y
Sbjct: 22552 MSIRWEEPYHDGGSKIIGYWVEKK-----ERNTILWVKENKVPCLECNYKVTGLVEGLEY 22606
Query: 1068 SFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
FR +N G S S+ SR I Q P D AP + + +++ L W Y+G
Sbjct: 22607 QFRTYALNAAGVSKASEASRPIMA-QNPVD-APGRPEVTDVTRSTVSLIWSA---PAYDG 22661
Query: 1128 NPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGP 1185
+ VGY I K G G+ L + +T+ L E Y +V A NA G
Sbjct: 22662 GSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG--- 22718
Query: 1186 WSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD 1245
V+ + ES + A + V + LVL V K
Sbjct: 22719 ----VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKP---- 22770
Query: 1246 TQPRFWLVEGNSSR------SAQLTGL--------------GKYVLYEVQVLAFTRIGDG 1285
+P+ +G+ S Q TG GKY L +
Sbjct: 22771 -EPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS-- 22827
Query: 1286 SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTA 1345
++ + LD PGP + V L W P G + + I R T+
Sbjct: 22828 ------VMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 22880
Query: 1346 NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEKRDRPQPPS 1404
N VE P+ Y T L + Y+FR+ A + G G E+ +V P PP
Sbjct: 22881 NWVIVEGECPTL-SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPG 22939
Query: 1405 RPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
P ++ +++ W +P SDG + + Y + RE S RW + + V
Sbjct: 22940 IP--EEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKV 22997
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVTPHTTTSVL 1519
L Y+FRV A N G+SE SE S ++ + + P AP ++ T H S+
Sbjct: 22998 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKH---SIS 23054
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
+ W P D I+ G+ L W + + ++RN
Sbjct: 23055 LAWTKPMYDGGTDIV----------------GYVLEMQEKDTDQWYRVHTNATIRN---- 23094
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSS-------PPQEVFVGE-AVPTAAPRNVV 1631
T++ + +L ++Y R++ N G S P + + + + + + V
Sbjct: 23095 --TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVT 23152
Query: 1632 VHGATATQL--DVTWEPPPL---DSQNGDIQGYKIY-FWEAQRGNLTERVKTLFLAENSV 1685
+ + +L V+ PPP+ Q D+ I E+ + ++V + ++
Sbjct: 23153 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTI 23212
Query: 1686 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
+ +N +G + V V ++ G P SVK E++ SV ++WE
Sbjct: 23213 EAENQSGKKSATVLVKVYDTPGPCP------------------SVKVKEVSRDSVTITWE 23254
Query: 1746 APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1805
P G +V + + + TV K + L+ ++ L EG Y FR+ +
Sbjct: 23255 IPTIDGGAPVNNYIVEKREA---AMRAFKTVTTKCSKTLY-RISGLVEGTMYYFRVLPEN 23310
Query: 1806 -FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARP 1863
+ G E + E P + ++ S + + W G +T YV+EA
Sbjct: 23311 IYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK 23370
Query: 1864 SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
+ W +K + + + ++ L G Y FR+ A N+ G P +V Q
Sbjct: 23371 AGTERW---MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 23425
Score = 201 bits (512), Expect = 5e-51
Identities = 369/1646 (22%), Positives = 603/1646 (36%), Gaps = 237/1646 (14%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVIDGMS----- 418
++ LV F+ A+N AG + + T I + P LD T+ DG++
Sbjct: 14030 VTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGD 14089
Query: 419 --VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ A G P P +W K + + + TP S L I DAG YT
Sbjct: 14090 TIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSS-MLTIKYATRKDAGEYTIT 14148
Query: 477 ATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVTHDPRV 525
ATN G + V I+ +++ + T S + + R
Sbjct: 14149 ATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRE 14208
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRS 581
T R +W + + H +L + Y RV + G +S
Sbjct: 14209 TSRLLWTVVSEDIQSCRHVATKLIQGNE-------------YIFRVSAVNHYGKGEPVQS 14255
Query: 582 AHLRVRQL---PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWT 637
+++ P PE P +S V + ++W +P D G S + Y +E E +
Sbjct: 14256 EPVKMVDRFGPPGPPEKP--EVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRW 14313
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQN 696
V V GL +Y+FR+ A N G G S+ ++ V + + P PP N
Sbjct: 14314 VRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 14373
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILK--GYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
+ T +S + W P H +G L+ GY++ + G + T + ++
Sbjct: 14374 PHVTDTTKKSASLAWGKP---HYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVV 14430
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
DL Y ++A N AG+G + + + + P + AE + +R
Sbjct: 14431 PDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVEREMAPDFELDAELRRTLVVR----- 14484
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
G + + P + VT +D+I++ + ++ TE FT ++
Sbjct: 14485 ----------AGLSIRIFVPIKGRPAPEVTWT---KDNINLKNRANIEN-TESFTLLII- 14529
Query: 875 TTPGDGPRSTPQLVRTHE---------------DVPGPVGHLSFSEILDTSLKVSWQEPG 919
P T + V T E D PGPV +L ++I S+ + W P
Sbjct: 14530 --PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14587
Query: 920 EKNGI-LTGYRISWEEYNR----TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
G +T Y + E R T T H Y+VTGL+ Y V A
Sbjct: 14588 IDGGSRITNYIVEKREATRKSYSTATTKCH-----KCTYKVTGLSEGCEYFFRVMAENEY 14642
Query: 975 GQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVG 1033
G G+ + +T E P PP +L I +I +V+L + +P +DG + I+ +++EAQ
Sbjct: 14643 GIGEPTETT-EPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRK 14701
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
++W I + V +L Y+F++ VN G S
Sbjct: 14702 ---GSDQWTHITTVKG----LECVVRNLTEGEEYTFQVMAVNSAGRS------------- 14741
Query: 1094 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESV-------GYKIKYSRSDGHGK 1146
AP + P V +T LPE++ G + + K++
Sbjct: 14742 APRESRPVIVKEQTM-----------LPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKP 14790
Query: 1147 TLSHVVQDRVERDYTIEDLEEW-TEYRVQVQAFNAIGSGPWSQT---VVGRTRESV---- 1198
T++ D++ + + E T + + SGP+ T +VG + +
Sbjct: 14791 TVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQV 14850
Query: 1199 -----PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV 1253
P +GP ++ S + W + PE D + Y V ++ DS T
Sbjct: 14851 HDIPGPPTGPIKFDEVS--SDFVTFSW-DPPENDGGVPISNYVVEMRQTDSTTWVELATT 14907
Query: 1254 EGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEV 1312
++ A T L + Y+ +V A R G G + I+ VPGPP V
Sbjct: 14908 VIRTTYKA--TRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAV 14965
Query: 1313 RTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY 1371
S+ + W P + G IL Y + + + L P + ++GL Y
Sbjct: 14966 TKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPG-NIFKSSGLTDGIAY 15024
Query: 1372 LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE-----------DVRARSVLL 1420
FR+ A+ G + +P PS PM+ + ++ +V L
Sbjct: 15025 EFRVIAENMAG--------------KSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTL 15070
Query: 1421 SW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKAT 1479
W +P G + Y ++ R+LP+GRW + S + + F V L +Y+FRV A
Sbjct: 15071 KWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFS-NILENEFTVSGLTEDAAYEFRVIAK 15129
Query: 1480 NDIGD-SEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFR 1538
N G S SE S+++T EAP I T +L + FR
Sbjct: 15130 NAAGAISPPSEPSDAITCRDDV--EAPKIKVDVKFKDTVILKAGE------------AFR 15175
Query: 1539 IRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIR 1598
+ + G P W++ + + + +NK
Sbjct: 15176 LEA-----------DVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRR-D 15223
Query: 1599 MSVYNAVGEGPSSPPQEVFVGEAVPTAAPRN--VVVHGATATQLDVTWEPPPLDSQNGDI 1656
Y P + +F + + P + V T+ + ++W PP LD I
Sbjct: 15224 SGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPP-LDDGGAKI 15282
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
Y + E R T + + + +K+ L Y+ V A N G G S P
Sbjct: 15283 DHYIVQKRETSRLAWTNVASEVQVTK--LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 15340
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIV 1774
P P + + + +T S+ V W P G E + E + +
Sbjct: 15341 VLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS-EIINYIVERRDKAG--QRWI 15397
Query: 1775 TVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGA------PGPP 1828
+ K + L KV L EG Y FRI A+ I A T P A PGPP
Sbjct: 15398 KCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN---AAGISAPSPTSPFYKACDTVFKPGPP 15454
Query: 1829 GVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 1886
G P ++ S S+I+I W+ G IT Y++E +E W I+ + +SYT +
Sbjct: 15455 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 15514
Query: 1887 MDILKPGVSYDFRVIAVNDYGFGTPS 1912
L Y R+ A+N G G P+
Sbjct: 15515 G--LTENQEYKIRIYAMNSEGLGEPA 15538
Score = 201 bits (510), Expect = 8e-51
Identities = 370/1602 (23%), Positives = 611/1602 (38%), Gaps = 215/1602 (13%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G +V L G P P ++W+K +L + +L + + D+G
Sbjct: 13001 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLCTLELFSVNRKDSG 13059
Query: 472 TYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVT 520
YT A NS G A+ L V A +I K D++++ S +
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119
Query: 521 HDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
D R T R W + AT+ S +L C G D
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFR----------ICAENKYGVGDPV 13169
Query: 581 SAHLRVRQLPHAP----EHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP 635
+ + P+ P + PV +S + + + ++W P D G SP+ Y+LE E A
Sbjct: 13170 FTEPAIAKNPYDPPGRCDPPV--ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAV 13227
Query: 636 -WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP--PTA 692
WT + + T + GL Y+FR+ A+N G G+ S D + + +P P
Sbjct: 13228 NWTKVNRKPIIERT-LKATGLQEGTEYEFRVTAINKAGPGKPS-DASKAAYARDPQYPPG 13285
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIR--------YCLAGLPVGYQFKNI 744
PP T S+ + W P + I+ GY++ + LP Q
Sbjct: 13286 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPII-GYLVEVKRADSDNWVRCNLPQNLQK--- 13341
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T +V L+ ED T Y+ V A N G S + + + P G + A+
Sbjct: 13342 TRFEVTGLM-ED----TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 13396
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT-ARPNFQDSIHVGFVSGLKK 863
+ +R G + + P + +T ++PN +G K
Sbjct: 13397 TLILR---------------AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDI---K 13438
Query: 864 FTEYFTSVLC------------FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
T++ T + C T + +V D PGP +++ EI S
Sbjct: 13439 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13498
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
V+W+ P G + Y + + R + + T +RV L +Y V A
Sbjct: 13499 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT-SFRVANLEEGKSYFFRVFA 13557
Query: 971 MTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVE 1029
G G T + + PGP +L + ++ S ++ ++ P DG + I ++V+
Sbjct: 13558 ENEYGIGD-PGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 13616
Query: 1030 AQVGVVGEGEEWL-LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
+ E +W ++ LS + A+ DL Y+FR+ N G PS+
Sbjct: 13617 ----FLTEENKWQRVMKSLSLQYSAK-----DLTEGKEYTFRVSAENENGEGTPSEI--- 13664
Query: 1089 IQTLQAPPDMAPANVSLR-------TASETSLW-----LRWMPLPEMEYNGNPESVGYKI 1136
T+ A D+ ++ L+ A E S + ++ P P + + + +
Sbjct: 13665 --TVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT 13722
Query: 1137 KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGS--GPWSQTVVGRT 1194
+ S V V + D ++ + + N G+ G S VVG+
Sbjct: 13723 RVS-----------VESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13771
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE 1254
+P+ GP + T+ +M ++W+ P+ D + Y + +++DS
Sbjct: 13772 --GIPT-GPIKFDEV--TAEAMTLKWAP-PKDDGGSEITNY--ILEKRDSVNNKWVTCAS 13823
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTR--IGDGSPSHPPILERTLD--DVPGPPMGILFP 1310
+ ++T L + + Y +V A + +G+G S P + D D P PP +
Sbjct: 13824 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV--- 13880
Query: 1311 EVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTT----ANTATVEVLAPSARQYTATGL 1365
+VR SV L W P G I Y + + + AN + + R + TGL
Sbjct: 13881 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM-----RDFKVTGL 13935
Query: 1366 KPESVYLFRITAQTRKGWGEAA---EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW 1422
Y FR+ A G G+ + E +V D PP +P V ++ SV L W
Sbjct: 13936 TEGLEYEFRVMAINLAGVGKPSLPSEPVVAL----DPIDPPGKPEVI--NITRNSVTLIW 13989
Query: 1423 -EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND 1481
EP DG + Y ++ R+LPS W + + V+ +F V L Y+FR++A N
Sbjct: 13990 TEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 14048
Query: 1482 IGDSEFSEESESLTTLQAAPD-EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIR 1540
G S SES T+ + EAPTI+ P +D G I+
Sbjct: 14049 AG--AISAPSESTETIICKDEYEAPTIVL-------------DPTIKD-------GLTIK 14086
Query: 1541 YRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL----SRPSLTQYELDNLNKHRRYE 1596
+ + L ++ G P ++W++ ++ S P+ + + + E
Sbjct: 14087 AGDTIV--LNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14144
Query: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
++ N G + + V V P V + +A + +TW PP L+ I
Sbjct: 14145 YTITATNPFG----TKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP-LEDGGSPI 14199
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
+ Y + E R L V + V K + G Y+ V+A N G G +S P
Sbjct: 14200 KSYILEKRETSR-LLWTVVSEDIQSCRHVATKLIQG-NEYIFRVSAVNHYGKGEPVQSEP 14257
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKI 1773
+ + P P + S +T + VSW+ P G + GY + + V I
Sbjct: 14258 VKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAI 14317
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPPGV 1830
T S L KV L EG TY FR+ A+ GP EA+ + + A PGPP
Sbjct: 14318 KTPV----SDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 14373
Query: 1831 PIIVRYSSAIA-IHWSSGDPGKG-PITRYVIEARPSDEGLWDILIKDIPKEVSSYT-FSM 1887
P + + A + W G IT YV+E + + W IKD T F +
Sbjct: 14374 PHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVV 14430
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPS-SPSQSVPAQKANPFYE 1928
L+ Y+FR+ A+ND G G P+ P + ++ P +E
Sbjct: 14431 PDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFE 14472
Score = 200 bits (508), Expect = 1e-50
Identities = 369/1617 (22%), Positives = 631/1617 (39%), Gaps = 210/1617 (12%)
Query: 477 ATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
A N+ GV + SA + R PP + V +GT ++V + P T+ W
Sbjct: 9788 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLT--W 9845
Query: 532 EKDGATLGTESHP--------RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
K P ++ +D +L I Q+ D G YT ++ G S+
Sbjct: 9846 FKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 9905
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
L V P P P+ +V + L+W P D G S + Y++E E N V ++S
Sbjct: 9906 LNVLGRPGPPVGPIK-FESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSS 9964
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--------PP 694
+PK + T+ L+ Y FR+ A N G G+ L EP TA P
Sbjct: 9965 -EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE--------PLDSEPETARNLFSVPGAP 10015
Query: 695 QNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
S T S+ + W+ P E + GY + ++K + + + L
Sbjct: 10016 DKPTVSSVTRNSMTVNWEEP-EYDGGSPVTGYWLEMKDT---TSKRWKRVNRDPIKAMTL 10071
Query: 755 ------EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST-- 806
LI ++Y+ V A N+AG+G S T + P PPG + T+ T
Sbjct: 10072 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD-PIAPPGPPFPKVTDWTKS 10130
Query: 807 TIRFTWNAP---SPQFINGINQGYKLIA---WEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ W+ P + G YK WE +++EV V+G
Sbjct: 10131 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL-----------VVTG 10179
Query: 861 LKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP- 918
LK+ Y V G G P ++ + + P D L S ++
Sbjct: 10180 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP----------DLQLDASVRDRI 10229
Query: 919 -GEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVT-GLTALTTYTI---------E 967
G++ RI + VT + TL T TA+++ +
Sbjct: 10230 VVHAGGVI---RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQG 10286
Query: 968 VAAMTSKGQGQVSASTISSGVPPELPGPP-TNLGISNIGPRSVTLQ-FRPGYDGKTSISR 1025
V ++ +K + TI V ++PGP T N+ S L F P DG + I+
Sbjct: 10287 VYSLLAKNEAGERKKTIIVDVL-DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITN 10345
Query: 1026 WLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 1085
+++E + + W + +A V L Y FR+ N +G P +
Sbjct: 10346 YVIEKRES---DRRAWTPVTYTVTRQNAT---VQGLIQGKAYFFRIAAENSIGMGPFVET 10399
Query: 1086 SRKIQTLQAPPDMA--PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG 1143
S + ++ P + P ++ ++ ++ ++ L W P +Y+G E + Y ++ SR G
Sbjct: 10400 SEAL-VIREPITVPERPEDLEVKEVTKNTVTLTWNP---PKYDGGSEIINYVLE-SRLIG 10454
Query: 1144 HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRESVPS 1200
K + + R YT++ L+E Y +V A N +G G S + + + + P+
Sbjct: 10455 TEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPT 10514
Query: 1201 ---SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS-DTQPRFWLVEGN 1256
++ + ++ R+S P+ + V+ ++ T P +E
Sbjct: 10515 LHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALE-- 10572
Query: 1257 SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTT 1315
A+ + GKY + + + + S + + D PGPP+G + F EV
Sbjct: 10573 -KIKAKRSDSGKYCVV---------VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622
Query: 1316 SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV-YLFR 1374
+ + W+PP G + I + + V + SA+ E Y+FR
Sbjct: 10623 YMVISWKPPLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKLLEGKDYIFR 10680
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
I A+ G + + + + R R P P +P+V + V S L++W DG P+
Sbjct: 10681 IHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE--VTKDSALVTWNKPHDGGKPIT 10738
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESES 1493
Y ++ RE S RWA + H + F V L Y+FRV A N+IG + S S+
Sbjct: 10739 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10798
Query: 1494 LTTLQAAPDEAPTILSVTPHTT-TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGF 1552
+ +P + TT SV + WQPP D +LG+ + Y+++ E R
Sbjct: 10799 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG-GSKILGYIVEYQKVGDEEWR-- 10855
Query: 1553 TLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSS 1611
R + P S P T+Y++ L + Y+ R+ NA GE P+
Sbjct: 10856 --RANHTPE---------------SCPE-TKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 10897
Query: 1612 PPQEVFVGEAVPTAAPRNVVVHGATATQLDV-TWEPPPLDSQNGDIQGYKIYFWEAQRGN 1670
P+ V V + + P +++ A + + + L + + K+ + + R
Sbjct: 10898 VPEPVLVKDRL---EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA 10954
Query: 1671 LTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSV 1730
T+ + + ++++N + S+ N AG T + P P +
Sbjct: 10955 PTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGS---KTVSVKVLVLDKPGPPRDL 11011
Query: 1731 KFSELTTTSVNVSWEAP------QFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPL 1784
+ SE+ S ++W+ P N ++E + SP+ SK K +
Sbjct: 11012 EVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSK-----KKSHF-- 11064
Query: 1785 WLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAP--GPPGVPIIVRY----S 1837
K L EG Y FR+ A+ + GP +E T P + PPG P + +
Sbjct: 11065 ---AKHLNEGNQYLFRVAAENQYGRGPFVE---TPKPIKALDPLHPPGPPKDLHHVDVDK 11118
Query: 1838 SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSY 1896
+ +++ W+ D G PIT Y++E + +EG D + K V++ + L+ G +Y
Sbjct: 11119 TEVSLVWNKPDRDGGSPITGYLVEYQ--EEGTQDWIKF---KTVTNLECVVTGLQQGKTY 11173
Query: 1897 DFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEEWWFLVVIALVGLIFI--LLLVFVLIIR 1954
FRV A N G G P + ++P + L V + GL+ + F IIR
Sbjct: 11174 RFRVKAENIVGLGLPDT---TIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIR 11230
Query: 1955 GQSKKYAKKTDSGNSAKSGALGHSEMMSLDESSFPALELNNRRLSVKNSFCRKNGLY 2011
G AK T G+ K+ E +++ +F ++ L++KN R G Y
Sbjct: 11231 GVPVPTAKWTTDGSEIKT-----DEHYTVETDNFSSV------LTIKNCLRRDTGEY 11276
Score = 200 bits (508), Expect = 1e-50
Identities = 379/1720 (22%), Positives = 629/1720 (36%), Gaps = 216/1720 (12%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT-LENTLVILSTVAPDAGRYY 182
V H + ++ P P VTW + R +P + I T + +++VI + G Y
Sbjct: 10230 VVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYS 10289
Query: 183 VQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANAR 242
+ A N+ KT I + V +V GP T + T+ + + E +
Sbjct: 10290 LLAKNEAGERKKT---IIVDVLDVPGPVG----TPFLAHNLTNESCKLTWFSPE--DDGG 10340
Query: 243 PLIKLHIIWKKDG---VLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG 299
I ++I K++ + + T+ A ++ A P V
Sbjct: 10341 SPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETS 10400
Query: 300 AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPP------PSITWYKDAAVVEVEK 353
L + EP + PER E+++V PP I + ++ ++ EK
Sbjct: 10401 EALVIREP---ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10457
Query: 354 LTRFRQRN--DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL-- 409
+ N + GL DT ++ A N G+ + S + + L
Sbjct: 10458 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10517
Query: 410 ----DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
T+ G + L SG P+P ++W K E + + TP I
Sbjct: 10518 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 10577
Query: 466 HISDAGTYTCLATNSRG----------------------VDEASADLVVWARTRITKPPQ 503
SD+G Y + NS G DE + D +V + KPP
Sbjct: 10578 R-SDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVIS----WKPPL 10632
Query: 504 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
D S + + + + +W + ++ ++ G +I + + +
Sbjct: 10633 DDG------GSKITNYIIEKKEVGKDVW-MPVTSASAKTTCKVSKLLEGKDYIFRIHAEN 10685
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLI 623
+ + ++S DS A R R +P AP+ P+ T V + + +TW KP DG P+
Sbjct: 10686 LYGISDPLVS----DSMKAKDRFR-VPDAPDQPIVT--EVTKDSALVTWNKPHDGGKPIT 10738
Query: 624 RYILEMSEN-NAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
YILE E + W + T V L+ Y+FR+ A N++G G S ++
Sbjct: 10739 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10798
Query: 683 VSLPEE-PPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQF 741
V + +PP N A T S+ + WQPP + IL GYI+ Y G +
Sbjct: 10799 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKIL-GYIVEYQKVGDEEWRRA 10857
Query: 742 KNITDA-DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV-H 799
+ ++ + L Y+ V A N+AG + V E L PP +
Sbjct: 10858 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES-DPAHVPEPVLVKDRLEPPELILD 10916
Query: 800 AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS 859
A I+ I G+ + + W+ E + T D VG
Sbjct: 10917 ANMAREQHIKVGDTLRLSAIIKGV--PFPKVTWKKEDRDAPTKARI-----DVTPVGSKL 10969
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
++ + T T + D PGP L SEI S ++W+EP
Sbjct: 10970 EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL 11029
Query: 920 EKNG-ILTGYRI--------SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
+ G ++T Y + W + T+ + +H+ + L Y VAA
Sbjct: 11030 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH---------LNEGNQYLFRVAA 11080
Query: 971 MTSKGQGQV--SASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWL 1027
G+G + I + P PGPP +L ++ V+L + +P DG + I+ +L
Sbjct: 11081 ENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYL 11140
Query: 1028 VEAQVGVVGEG-EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS-PPSQP 1085
VE Q EG ++W+ ++N V L Y FR++ NIVG P +
Sbjct: 11141 VEYQ----EEGTQDWIKFKTVTN----LECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI 11192
Query: 1086 SRKIQTLQAPPD-------MAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY 1138
+ Q PP + V T +R +P+P ++ + +
Sbjct: 11193 PIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI------ 11246
Query: 1139 SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESV 1198
++D H V D TI++ Q+ NA GS V T V
Sbjct: 11247 -KTDEH----YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGS---KTVAVHLTVLDV 11298
Query: 1199 PS--SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV--E 1254
P +GP N+ L T M + W + P+ D V+ Y V + DT+ W V
Sbjct: 11299 PGPPTGPINI--LDVTPEHMTISW-QPPKDDGGSPVINYIV----EKQDTRKDTWGVVSS 11351
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVR 1313
G+S ++ L K Y +V A +IG G P P + + P PP + ++
Sbjct: 11352 GSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDIT 11411
Query: 1314 TTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+ + W P + G I Y + R T V + ++ TGL + Y
Sbjct: 11412 ENAATVSWTLPKSDGGSPITGYYMERR--EVTGKWVRVNKTPIADLKFRVTGLYEGNTYE 11469
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLS 1430
FR+ A+ G + + + + P PP P ++ + R + L+ +P SDG S
Sbjct: 11470 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS-RETADLVWTKPLSDGGS 11528
Query: 1431 PVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
P+ Y ++ ++ + +W + +F V L Y+FR+KA N +G+ E E
Sbjct: 11529 PILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11588
Query: 1491 SESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLR 1550
+ES+ A IL P V R + + +G IR
Sbjct: 11589 AESVI--------AKDILH-PPEVELDVTCR-------DVITVRVGQTIRILA------- 11625
Query: 1551 GFTLRGINNPGATWAELTSMY-------SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
++G P TW + + +++L R L E + H +Y I S N
Sbjct: 11626 --RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRAD-HGKYII--SAKN 11680
Query: 1604 AVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF 1663
+ G S V +N+ V T ++WE PLD+ +I + + +
Sbjct: 11681 SSGHAQGS----AIVNVLDRPGPCQNLKVTNVTKENCTISWE-NPLDNGGSEITNFIVEY 11735
Query: 1664 -------WEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP---RS 1712
W ++T+R +K LA N Y V A N G GP
Sbjct: 11736 RKPNQKGWSIVASDVTKRLIKANLLANNE-----------YYFRVCAENKVGVGPTIETK 11784
Query: 1713 TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
TP P P ++ ++ T V + W P + G
Sbjct: 11785 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGG 11824
Score = 198 bits (503), Expect = 5e-50
Identities = 328/1450 (22%), Positives = 557/1450 (38%), Gaps = 178/1450 (12%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSA 582
P+VT W K G +D L I + D G Y+ +++ G +
Sbjct: 12331 PKVT----WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12386
Query: 583 HLRVRQLPHAPEHPVATL--STVERRAINLTWTKPF-DGNSPLIRYILEMSE-NNAPWTV 638
++RV P PV+ L S V + + +++W P DG S + YI+E E + W+
Sbjct: 12387 NVRVLDTPG----PVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWST 12442
Query: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--PPQN 696
+ V K TS V LVP Y FR+ AVN+ G G D + L +P + PP+
Sbjct: 12443 VTPEV--KKTSFHVTNLVPGNEYYFRVTAVNEYGPG-VPTDVPKPVLASDPLSEPDPPRK 12499
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED 756
+ + T S + W PP + GYI Y P + D+ +L++
Sbjct: 12500 LEVTEMTKNSATLAWLPPLRD-GGAKIDGYITSYREEEQPADRWTEYSVVKDL-SLVVTG 12557
Query: 757 LIIWTNYEIEVAAYNSAGL-------GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIR 809
L Y+ VAA N+ G+ GVY +K L + P + +A I
Sbjct: 12558 LKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE---QLLPPKILMPEQITIKAGKKLRIE 12614
Query: 810 -FTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYF 868
+ P P W+ ++E VT + DS + + + + +
Sbjct: 12615 AHVYGKPHP-----------TCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 12663
Query: 869 TSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
S+ + G + +V D PG P S+I + +SW P E G +T
Sbjct: 12664 YSLTAENSSGTDTQKIKVVVM---DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 12720
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTIS 985
Y + + +R + VT RV L Y V A G + +++ +
Sbjct: 12721 NYIVEKCDVSRGDW-VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 12779
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLI 1044
+ P +P P N ++ + + + + RP DG + I +L+E + E L+
Sbjct: 12780 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK-------ERNSLL 12832
Query: 1045 HQLSNEPDARSMEVP--DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQT-LQAPPDMAPA 1101
+N+ RS E P L YSFR+ +N G+SPPS+P+ + + P P
Sbjct: 12833 WVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE 12892
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
+ + ++ + +W R +++G + +GY ++ + G + ++ + +Y
Sbjct: 12893 VIDVTKSTVSLIWAR------PKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 12946
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRW 1220
T LEE +Y+ + A A+ P S+ T + + P + S + V+
Sbjct: 12947 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPVT--ILAENVPPRIDLSVAMKSLLTVKA 13004
Query: 1221 SEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLG-KYVLYEVQVLAF 1279
+ L V K + + W +G + A+ + + L +++ +
Sbjct: 13005 G-------TNVCLDATVFGKPMPTVS----WKKDGTLLKPAEGIKMAMQRNLCTLELFSV 13053
Query: 1280 TRIGDG---------SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
R G S S ++ + D PGPP + ++ + L W+PP G
Sbjct: 13054 NRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS 13113
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA-EA 1389
+ I + T+ N A V P + L Y FRI A+ + G G+
Sbjct: 13114 EITNYIVDKRETSRPNWAQVSATVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTE 13172
Query: 1390 LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWA 1448
+ D P P++ ++ + +SW+ P DG SP+ Y ++ RE + W
Sbjct: 13173 PAIAKNPYDPPGRCDPPVI--SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWT 13230
Query: 1449 LHSASVSHNASSFIVDR------LKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-P 1501
+ I++R L+ T Y+FRV A N G + S+ S++ P
Sbjct: 13231 KVNRKP-------IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYP 13283
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
P V T +SV + W PA D + I+ G+ +
Sbjct: 13284 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPII----------------GYLVEVKRADS 13327
Query: 1562 ATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG-EGPSSPPQE----- 1615
W +++ T++E+ L + +Y+ R+ N +G PS P +
Sbjct: 13328 DNWVRCNLPQNLQK------TRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 13381
Query: 1616 -VFVGEAVPTAAPRNVVVHGATATQ---LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL 1671
+ E A R ++ A T + V PPP KI W NL
Sbjct: 13382 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPP-----------KI-TWSKPNVNL 13429
Query: 1672 TERV-----KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSA 1726
+R+ T F + ++ +N+ Y A + N+ G + T P
Sbjct: 13430 RDRIGLDIKSTDF--DTFLRCENVNKYDAGKYILTLENSCG---KKEYTIVVKVLDTPGP 13484
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P +V E++ S V+WE P G +V + + S + T K +
Sbjct: 13485 PVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTS----F 13540
Query: 1787 KVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAPGPPGVPIIVR--YSSAIAIH 1843
+V +L EG +Y FR+ A+ + G E + PGP V + VR S+ +I
Sbjct: 13541 RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQ-TPGPV-VDLKVRSVSKSSCSIG 13598
Query: 1844 WSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
W G I YV++ ++E W ++K + S +S L G Y FRV A
Sbjct: 13599 WKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-----SLQYSAKDLTEGKEYTFRVSA 13652
Query: 1903 VNDYGFGTPS 1912
N+ G GTPS
Sbjct: 13653 ENENGEGTPS 13662
Score = 195 bits (495), Expect = 5e-49
Identities = 428/1972 (21%), Positives = 746/1972 (37%), Gaps = 272/1972 (13%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP 135
++++ L F+R N+ G R+ + V E E +RA
Sbjct: 20127 HVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAG 20186
Query: 136 R-------IASFPQPQVTWFRDGRKIPPSSRI--AITLEN-TLVILSTVAPDAGRYYVQA 185
I+ P P+VT RDG + + R IT EN T+ + +V DAGRY + A
Sbjct: 20187 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 20246
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVA--------GTSEVTLEC 237
N T I + V + GP P P +I SV G S+VT
Sbjct: 20247 ANSSG---TTKAFINIVVLDRPGP--PTGPVVISDITEESVTLKWEPPKYDGGSQVTNYI 20301
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI---------SDHNRRLTIPNPTG-SDAGYYECEAV 287
+ +W + ++ + ++ R+ N G SD C V
Sbjct: 20302 LLKRETSTA---VWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTV 20358
Query: 288 LRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAA 347
+ P +++ + ++ VV + K SI W K
Sbjct: 20359 KLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD--RNSILWQKANK 20416
Query: 348 VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS--------------- 392
+V + T F+ +GL+ + F+ +A NAAG + S
Sbjct: 20417 LVI--RTTHFKVTTIS----AGLIYE----FRVYAENAAGVGKPSHPSEPVLAIDACEPP 20466
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRF 452
+ +T I+ N DG S + P W K F
Sbjct: 20467 RNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS------------F 20514
Query: 453 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV-------VWARTRITKPPQDQ 505
T + +IS + + A N+ G +++V + I P +
Sbjct: 20515 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYT 20574
Query: 506 SVIK---GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWS 561
V+K GT + G++ P TI W KD L T + + + S+ I
Sbjct: 20575 EVVKYRAGTSVKLRAGISGKPAPTIE--WYKDDKELQTNALVCVENTTDLASILIKDADR 20632
Query: 562 GDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNS 620
+ G Y ++ +A G+ S + +++ P P P+ TV I L W P D G +
Sbjct: 20633 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIE-FKTVTAEKITLLWRPPADDGGA 20691
Query: 621 PLIRYILEMSENN-APWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKD 679
+ YI+E E + W+++ ++ +T ++ Y FR+ AVN G G+ +
Sbjct: 20692 KITHYIVEKRETSRVVWSMVSEHLEE--CIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20749
Query: 680 TERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII----RYCLAGL 735
V+ PP + T S+ + W P + I GY + + L
Sbjct: 20750 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI-SGYFLEKRDKKSLGWF 20808
Query: 736 PVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPP 795
V + T V L ++Y+ V A N+AG G +S +E+ P PP
Sbjct: 20809 KVLKETIRDTRQKVTGLTEN-----SDYQYRVCAVNAAGQGPFSEP-SEFYKAADPIDPP 20862
Query: 796 G---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDS 852
G + + ++I W+ P + + GY ++ +EEE T V+ + + +
Sbjct: 20863 GPPAKIRIADSTKSSITLGWSKPVYDGGSAVT-GY-VVEIRQGEEEEWTTVSTKGEVRTT 20920
Query: 853 IHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEI-LDTS 910
+V VS LK Y+ V G G P + V+ + + P EI LD +
Sbjct: 20921 EYV--VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP-------EIDLDVA 20971
Query: 911 LKVSW-QEPGEKNGILTGYR------ISWEEYNRTNTRVTHY-LPNVTLEYRVTGLTALT 962
L+ S + GE +L ++ ++W + + Y + N +T
Sbjct: 20972 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 21031
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKT 1021
T + G G+ +ST+S V + P L + ++ +VTL + P DG +
Sbjct: 21032 NDTGKYILTIENGVGEPKSSTVSVKVL-DTPAACQKLQVKHVSRGTVTLLWDPPLIDGGS 21090
Query: 1022 SISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +++E + W ++ S++ + S ++ DL+ T + FR+ N +G
Sbjct: 21091 PIINYVIEKRDATK---RTWSVV---SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 21144
Query: 1082 PSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS 1141
P + + ++ + P + ++S++ +++TS+ L W + +++G Y ++ R
Sbjct: 21145 PCETTEPVKAAEVPAPIR--DLSMKDSTKTSVILSWT---KPDFDGGSVITEYVVE--RK 21197
Query: 1142 DGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPS 1200
+T SH + + + L+E + +V A N G S P +
Sbjct: 21198 GKGEQTWSHAGISKT-CEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------VT 21243
Query: 1201 SGPTNVSALATTSSSMLVRWSEVPEAD---RNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
GP V L T V S++P A R G + ++ YK K + WL +G
Sbjct: 21244 IGPITVKELIITPE---VDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSIS--WLKDGLP 21298
Query: 1258 SRSAQLTGLGKY---VLYEVQVLA------FTRIGDGSPSH--PPILERTLDDVPGPPMG 1306
+ ++ K + ++ +T I D + PI TL P
Sbjct: 21299 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 21358
Query: 1307 ILFPEVRTTSVRLIWQPPAAPNG-IILAYQITHRLNTTTANTATVEVLAPSARQ-YTATG 1364
I F E++ SV L W P G I Y I R T+ T V + AR +
Sbjct: 21359 IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR---ETSQTNWKMVCSSVARTTFKVPN 21415
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWE 1423
L ++ Y FR+ A+ R G + + ++ + + R P PP +P++ +V + + L+W+
Sbjct: 21416 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY--NVTSDGMSLTWD 21473
Query: 1424 -PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
P DG S V + ++ +E S W + S + + L Y+FRV A N
Sbjct: 21474 APVYDGGSEVTGFHVEKKERNSILWQKVNTSPI-SGREYRATGLVEGLDYQFRVYAENSA 21532
Query: 1483 GDSEFSEESE-SLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRY 1541
G S S+ S+ +L P P + VT T T ++W PP D + I+ G+ I
Sbjct: 21533 GLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETIT---LKWNPPLRDGGSKIV-GYSIEK 21588
Query: 1542 RELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSV 1601
R+ W N + S QY + L+ RYE R+
Sbjct: 21589 RQ----------------GNERWVRC-------NFTDVSECQYTVTGLSPGDRYEFRIIA 21625
Query: 1602 YNAVGEGPSSPPQE-----VFVGEAVPTAAP------RNVVVHGATATQLDVTWEPPPLD 1650
NAVG SPP + + E VP +++ + ++ + P+
Sbjct: 21626 RNAVGT--ISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVP 21683
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
G +I +R N+ T L S+ +++ T + +V A NA+G
Sbjct: 21684 RVTWFKDGVEI----EKRMNMEI---TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21736
Query: 1711 RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV 1770
+ Q P ++F+ +T + + W+AP + + C+P+
Sbjct: 21737 AEIKVKVQDTPGKVVGP--IRFTNITGEKMTLWWDAP------------LNDGCAPITHY 21782
Query: 1771 SKIVTVDVKGNSPL-WLKVKDLAE-----------GVTYRFRIRA-KTFTYGPEIEANVT 1817
++ + S L W ++D E G Y+FR+ A F G ++++
Sbjct: 21783 ----IIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPV 21838
Query: 1818 TGPGE-GAPGPPGVPIIVRYS-SAIAIHWSSGDP-GKGPITRYVIEARPSDEGLWDILIK 1874
+ P PG+P + ++I + W+ + G I +Y++E R W +I
Sbjct: 21839 VAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVIS 21898
Query: 1875 DIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQK-ANP 1925
P +S F + L G Y+F V+A N G G S S+ + ++ NP
Sbjct: 21899 KRP--ISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNP 21948
Score = 193 bits (490), Expect = 2e-48
Identities = 350/1604 (21%), Positives = 572/1604 (35%), Gaps = 169/1604 (10%)
Query: 378 FQCFARNAAGEVQTSTYLAVTS---IAPNIT-RGPLDSTVI--DGMSVVLACETSGAPRP 431
F+ A N GE S V +AP++ +G D + + + L G P P
Sbjct: 13648 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13707
Query: 432 AITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV 491
+++W+KGE LA+ ++ + + +L++ SDAG YT N G E + +
Sbjct: 13708 SVSWKKGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 13766
Query: 492 VWARTRITKPPQDQSVIKGTQASMVCGVTHDP--RVTIRYIWEK----DGATLGTESHPR 545
V + I P + ++ D YI EK + + S +
Sbjct: 13767 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 13826
Query: 546 IRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
R LH ++ + + G +P AP P + V
Sbjct: 13827 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP--PPPNIVDVRH 13884
Query: 606 RAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFR 664
+++LTWT P G SP+ Y LE E N+ + V GL Y+FR
Sbjct: 13885 DSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFR 13944
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEP-----PTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
+ A+N G G + SLP EP P PP T S+ + W P +
Sbjct: 13945 VMAINLAGVG-------KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP--KYD 13995
Query: 720 NG-ILKGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
G L GYI+ LP K N + + DL+ YE + A N+AG
Sbjct: 13996 GGHKLTGYIVE--KRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 14053
Query: 778 YSSKVTEW----------TLQGVPTVPPG-NVHAEATNSTTIRFTWNAPSPQFINGINQG 826
S+ TE T+ PT+ G + A T P P+ + ++
Sbjct: 14054 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPK--SSWSKA 14111
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQ 886
K I + ++T +T+ P + +K T T
Sbjct: 14112 GKDI-----RPSDITQITSTP-------TSSMLTIKYATRKDAGEYTITATNPFGTKVEH 14159
Query: 887 LVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
+ T DVPGP G + S + ++W P E G + Y + E +R V
Sbjct: 14160 VKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE 14219
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNI 1004
+ + T L Y V+A+ G+G+ V + + PGPP +SN+
Sbjct: 14220 -DIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNV 14278
Query: 1005 GPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNP 1063
+ T+ + RP DG + I+ + VE + E + + + +V L
Sbjct: 14279 TKNTATVSWKRPVDDGGSEITGYHVERR-----EKKSLRWVRAIKTPVSDLRCKVTGLQE 14333
Query: 1064 FTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPE 1122
+ Y FR+ N G PPS+ S + A P P+N + ++ S L W +
Sbjct: 14334 GSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAW---GK 14390
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G E GY +++ + + + DL+ +Y ++ A N G
Sbjct: 14391 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14450
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
G + V E V + A +++VR L ++ K
Sbjct: 14451 VG---EPAVIPDVEIVEREMAPDFELDAELRRTLVVRAG-----------LSIRIFVPIK 14496
Query: 1243 DSDTQPRFWLVEG-NSSRSAQLTGLGKYVL--------YEVQVLAFTRIGDGSPSHPPIL 1293
W + N A + + L Y+ T +
Sbjct: 14497 GRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14556
Query: 1294 ERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVL 1353
R L D PGP + + ++ SV L W P G + I + T + +T
Sbjct: 14557 VRVL-DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTK 14615
Query: 1354 APSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRP-MVQQED 1412
Y TGL Y FR+ A+ G GE E TTE + PS P + D
Sbjct: 14616 CHKC-TYKVTGLSEGCEYFFRVMAENEYGIGEPTE----TTEPVKASEAPSPPDSLNIMD 14670
Query: 1413 VRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTS 1471
+ +V L+W +P DG S + Y I+ + S +W H +V +V L
Sbjct: 14671 ITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWT-HITTV--KGLECVVRNLTEGEE 14727
Query: 1472 YKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKIN 1531
Y F+V A N G S P + V+++ Q +
Sbjct: 14728 YTFQVMAVNSAGRS-------------------------APRESRPVIVKEQTMLPE--- 14759
Query: 1532 GILLGFRIRYRELLY----EGLR-GFTLRGINNPGATWAELTSMYSM-RNLSRPSLTQYE 1585
L R Y++L+ + ++ + G P TW + + + ++ +
Sbjct: 14760 ---LDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 14816
Query: 1586 LDNLNKHRRYE---IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDV 1642
+ N+N+ R + ++ N VGE +V PT + ++ +
Sbjct: 14817 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGP---IKFDEVSSDFVTF 14873
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
+W+PP D I Y + + E T+ + K LT Y V A
Sbjct: 14874 SWDPPENDG-GVPISNYVVEMRQTDSTTWVELATTVI--RTTYKATRLTTGLEYQFRVKA 14930
Query: 1703 FNAAGDGPRSTPT--QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRL 1759
N G GP T P P + + + +T S+ +SW P G + GY +
Sbjct: 14931 QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHV 14990
Query: 1760 VYEPCSPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVT 1817
+ + + VSK + V GN K L +G+ Y FR+ A+ +
Sbjct: 14991 ERKERNGILWQTVSKAL---VPGNI---FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSE 15044
Query: 1818 TGPGEGAPGPPGVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKD 1875
PPG P+ + + + + W+ + G IT Y++E R G W +K
Sbjct: 15045 PMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW---LKA 15101
Query: 1876 IPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG-FGTPSSPSQSV 1918
+ F++ L +Y+FRVIA N G PS PS ++
Sbjct: 15102 NFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAI 15145
Score = 193 bits (490), Expect = 2e-48
Identities = 343/1510 (22%), Positives = 596/1510 (39%), Gaps = 171/1510 (11%)
Query: 473 YTCLATNSRG-VDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVT 526
+ +A N +G D S + + A+ + +P SV G + ++ P+ T
Sbjct: 16896 FRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT 16955
Query: 527 IRYIWEKDGATLGTESHPRIR--LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
I W KDG L + + LD +L I +T D G Y V + G + S +
Sbjct: 16956 IT--WTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQYGITVANVVGQKTASIEI 17012
Query: 585 RVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLLAS 642
P P+ PV V +I L+W P + G + YI++ + W V+ A+
Sbjct: 17013 VTLDKPDPPKGPVK-FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 17071
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERV--SLPEEPPTAPPQNVIAS 700
V T++ V L YQFR+ A N G+ F+ +++ + P + P PP A+
Sbjct: 17072 V--ARTTLKVTKLKTGTEYQFRIFAENRYGQS-FALESDPIVAQYPYKEP-GPPGTPFAT 17127
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED---- 756
+ S++IQW P + + ++ ++ R + +I VN ++ D
Sbjct: 17128 AISKDSMVIQWHEPVNNGGSPVIGYHLERK---------ERNSILWTKVNKTIIHDTQFK 17178
Query: 757 ---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWN 813
L YE V A N G+G +SK +E + P PPG I W
Sbjct: 17179 AQNLEEGIEYEFRVYAENIVGVGK-ASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 17237
Query: 814 APSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVL 872
P + G + + E+ + + +F + I F VSGL + Y V+
Sbjct: 17238 KPV------YDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVI 17291
Query: 873 CFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRI 930
G P + + ++V P +S ++ V+ E + G +
Sbjct: 17292 AKNAAGAISKPSDSTGPITAKDEVELP--RISMDPKFRDTIVVNAGETFRLEADVHGKPL 17349
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI--SSGV 988
E+ R + + + E + T AL ++ A GQ + AS + S
Sbjct: 17350 PTIEWLRGDKEIEE---SARCEIKNTDFKALLI--VKDAIRIDGGQYILRASNVAGSKSF 17404
Query: 989 PPEL-----PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEW 1041
P + PGPP + ++ + +L + P DG + IS ++VE + W
Sbjct: 17405 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRET---SRLAW 17461
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPA 1101
++ ++E S++V L Y FR+ VN G P + + + P
Sbjct: 17462 TVV---ASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPK 17518
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
++ + ++ S+ + W + +G E +GY ++ + D G + R+ +
Sbjct: 17519 SLEVTNIAKDSMTVCWN---RPDSDGGSEIIGYIVE--KRDRSGIRWIKCNKRRITDLRL 17573
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLV 1218
+ L E EY +V A NA G G P TV + + V GP TN + TT +S+ +
Sbjct: 17574 RVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITL 17633
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
W + P D +LGY V + D + G +++ L ++ Y+++V A
Sbjct: 17634 AWGK-PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17692
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH 1338
++G G + P + D + P + L E+R GI++ +
Sbjct: 17693 LNKVGLGEATSVPGTVKPEDKLEAPELD-LDSELR--------------KGIVVRAGGSA 17737
Query: 1339 RLNTTTANTATVEVL-APSARQYTATGLKPESVYLFRITAQT--RKGWGE---------A 1386
R++ T E+ + ++T + V +++ R G+
Sbjct: 17738 RIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG 17797
Query: 1387 AEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSG 1445
+++ VT + D P PP V++ VR S L WEP DG + V+ Y I RE S
Sbjct: 17798 SKSAFVTVKVLDTPGPPQNLAVKE--VRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--ST 17853
Query: 1446 RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAP 1505
R A + S + +SF V+ L Y FRV A N+ G E +++ A P P
Sbjct: 17854 RKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKA--AEPPSPP 17911
Query: 1506 TILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWA 1565
+++T + TS + W+ P D + +L G+ + E+ +G +++
Sbjct: 17912 GKVTLTDVSQTSASLMWEKPEHDGGSRVL-GYVV---EMQPKGTEKWSI----------- 17956
Query: 1566 ELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVP-- 1623
++ + + L+ + Y+ R+ YN G+ S P+ + V
Sbjct: 17957 ----------VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK---SDPRVLGVPVIAKDL 18003
Query: 1624 TAAPRNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA 1681
T P + + Q D+ E P + +I K + + T RV A
Sbjct: 18004 TIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVK----DGEPLKQTTRVNVEETA 18059
Query: 1682 ENSV---KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
++V K N + Y +V A N+AG + + P P V+F E++
Sbjct: 18060 TSTVLHIKEGNKDDFGKY--TVTATNSAGTATENLSVIVLEKPGPPVGP--VRFDEVSAD 18115
Query: 1739 SVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTY 1797
V +SWE P + G + Y + E +V+ V + +K+ L G Y
Sbjct: 18116 FVVISWEPPAYTGGCQISNY--IVEKRDTTTTTWHMVSATVARTT---IKITKLKTGTEY 18170
Query: 1798 RFRIRAKTFTYGP----EIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGK 1851
+FRI A+ YG + +A + P + PGPPG P + S + + W + G
Sbjct: 18171 QFRIFAEN-RYGKSAPLDSKAVIVQYPFK-EPGPPGTPFVTSISKDQMLVQWHEPVNDGG 18228
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
I Y +E + + LW L K ++ T +D G+ Y+F+V A N G G P
Sbjct: 18229 TKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD---EGLEYEFKVSAENIVGIGKP 18285
Query: 1912 SSPSQSVPAQ 1921
S S+ A+
Sbjct: 18286 SKVSECFVAR 18295
Score = 192 bits (489), Expect = 2e-48
Identities = 323/1397 (23%), Positives = 511/1397 (36%), Gaps = 198/1397 (14%)
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
R + L I + D GTYT + G+ R+ H+ V P P + T ++
Sbjct: 9150 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVT--DIKAE 9207
Query: 607 AINLTWTKPFD-GNSPLIRYILEM---SENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662
+ LTW P D G S + Y+++ S A W + + K + L+P Y+
Sbjct: 9208 SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK--LIPNGQYE 9265
Query: 663 FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722
FR+ AVN G K + V PP RT S+++ W PP ++ + I
Sbjct: 9266 FRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPI 9325
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED-------LIIWTNYEIEVAAYNSAGL 775
GY + G P + ++ A + + L+ L+ Y+ A N+AG+
Sbjct: 9326 -TGYWLEKREEGSP---YWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGI 9381
Query: 776 GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT---IRFTWNAPSPQFINGINQGYKLIAW 832
G S+ ++ + G P PPG T I W P+ + G + +
Sbjct: 9382 GP-PSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAK------DGGSPIKGY 9434
Query: 833 EPEQEEEVTMVTARPNFQDSIHVG---FVSGLKKFTEYFTSVLCFTTPGDGPRS--TPQL 887
E +EE T R N D + V LK+ +Y V G+ S T ++
Sbjct: 9435 IVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI 9494
Query: 888 VRTH-EDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYL 946
T ++ P + + L + P G T + SWE + + +
Sbjct: 9495 PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTP-KSSWEFDGKAKKAMKDGV 9553
Query: 947 PNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA------STISSGVP-PELPGPPTNL 999
++ + ++ + I + G+ ++A T + V ++PGPP +L
Sbjct: 9554 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9613
Query: 1000 GISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS--M 1056
+S+I S L ++ P DG I +++E + +G+ W ++ PD S
Sbjct: 9614 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVN-----PDCGSTTF 9665
Query: 1057 EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQA--PPDMAPANVSLRTASETSLW 1114
VPDL Y FR+R N G PP + ++ PPD P + + ++ ++
Sbjct: 9666 VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPD-PPIKLKIGLITKNTVH 9724
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ----DRVERDYTIEDLEEWTE 1170
L W P + +G Y ++ D G Q D E +T+EDL E E
Sbjct: 9725 LSWKP---PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGE 9781
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
Y +V+A NA G S TV GP + S L + EV E
Sbjct: 9782 YEFRVKAVNAAGVSKPSATV-----------GPCDCQRPDMPPSIDLKEFMEVEEGTNVN 9830
Query: 1231 LV-----------LGYKVMYKEKDS------DTQPRFWLVEGNSSRSAQLTGLGKYVLYE 1273
+V +K K+ D+ DT +V+ + + LY
Sbjct: 9831 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLY- 9889
Query: 1274 VQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIIL 1332
+ A +G S + + PGPP+G I F V + L W PP G +
Sbjct: 9890 -TITAVNNLGTASKE----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKI 9944
Query: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
+ + V P YT L Y+FRI AQ + G GE ++
Sbjct: 9945 TNYVIEKREANRKTWVHVS-SEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPE 10003
Query: 1393 TTEKR-DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALH 1450
T P P +P V V S+ ++W EP DG SPV Y ++ ++ S RW
Sbjct: 10004 TARNLFSVPGAPDKPTV--SSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRV 10061
Query: 1451 SASVSHNAS---SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
+ + S+ V L + Y+FRV A N G S S+ T P
Sbjct: 10062 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPF 10121
Query: 1508 LSVTPHTTTSVLIRWQPPAED---KINGILLGFR--------------IRYRELLYEGL- 1549
VT T +S + W PP +D K+ G ++ ++ +R +L+ GL
Sbjct: 10122 PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLK 10181
Query: 1550 ---------RGFTLRGINNPGATWAELTSMYSMRN-LSRP--SLTQYELDNLNKHRRYEI 1597
R + GI PG E+T + M++ L P L D + H I
Sbjct: 10182 EGAFYKFRVRAVNIAGIGEPG----EVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVI 10237
Query: 1598 RMSVYNAVGEGPS--------SPPQEVFV------------------------------G 1619
R+ Y + P+ + PQE + G
Sbjct: 10238 RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10297
Query: 1620 EA----------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG 1669
E VP + H T +TW P D I Y I E+ R
Sbjct: 10298 ERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPE-DDGGSPITNYVIEKRESDRR 10356
Query: 1670 NLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQG---QTQQAAPSA 1726
T T + + ++ L AY +AA N+ G GP ++ + P
Sbjct: 10357 AWTP--VTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 10414
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P ++ E+T +V ++W P++ G E V E S + G K V
Sbjct: 10415 PEDLEVKEVTKNTVTLTWNPPKYDGG-SEIINYVLE--SRLIGTEKFHKVTNDNLLSRKY 10471
Query: 1787 KVKDLAEGVTYRFRIRA 1803
VK L EG TY +R+ A
Sbjct: 10472 TVKGLKEGDTYEYRVSA 10488
Score = 190 bits (483), Expect = 1e-47
Identities = 365/1536 (23%), Positives = 598/1536 (38%), Gaps = 180/1536 (11%)
Query: 448 QLPRFTPLESGSLLISPTHISDAGT-------YTCLATNSRGV--DEASADLVVWARTRI 498
+LP +++ I TH G + +A N+ GV + + + + AR +
Sbjct: 16174 ELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEV 16233
Query: 499 TKPP-------QDQSVIKGTQASMV-CGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LD 549
P +D V+ ++ V + P TI+ W K L + I+ D
Sbjct: 16234 DPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQ--WIKGDQELSNTARLEIKSTD 16291
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAIN 609
SL + D G Y + + G S + +++V P PE PV +S V
Sbjct: 16292 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVV-ISGVTAEKCT 16350
Query: 610 LTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCA 667
L W P DG S +I YI+E E + WTV+ A+V + VT L+ Y FR+ A
Sbjct: 16351 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTK--LLEGNEYTFRIMA 16408
Query: 668 VNDVGKGQFSKDTERVSL-PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGY 726
VN G G+ + V+ P P AP + + T S+++ W+ P + IL GY
Sbjct: 16409 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV-TKDSMIVVWERPASDGGSEIL-GY 16466
Query: 727 IIRYCLAGLPVGYQFKNITDADVNNLLLE--DLIIWTNYEIEVAAYNSAGLGVYS--SKV 782
++ G ++ + L L LI +YE V+A N+AGL S S
Sbjct: 16467 VLE---KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAY 16523
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN-QGYKLIAWEPEQEEEVT 841
+ PP N +++ +W+ P + G QGY ++ E T
Sbjct: 16524 QKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI--YDGGCEIQGY-IVEKCDVSVGEWT 16580
Query: 842 MVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPV--- 898
M T P + ++ L+K EY + G G H DVPGP+
Sbjct: 16581 MCTP-PTGINKTNIEVEKLLEKH-EYNFRICAINKAGVGE---------HADVPGPIIVE 16629
Query: 899 GHLSFSEI-LDTSLK--VSWQEPGEKNGI--LTGYRISWEEYNRTNTRVTHY-LPNVTLE 952
L +I LD L+ ++ + G + G ++ + + + + +VT
Sbjct: 16630 EKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 16689
Query: 953 YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQ 1012
+ L + Y +T + ++ ++ V + P PP NL ++ I SV++
Sbjct: 16690 FTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL-DTPSPPVNLKVTEITKDSVSIT 16748
Query: 1013 FRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRM 1071
+ P DG + I ++VE + E ++N S ++ L Y FR+
Sbjct: 16749 WEPPLLDGGSKIKNYIVEKR-----EATRKSYAAVVTN-CHKNSWKIDQLQEGCSYYFRV 16802
Query: 1072 RQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPES 1131
N G P+Q + I+ + P P +++ + S+ L W + E++G +
Sbjct: 16803 TAENEYGIGLPAQTADPIKVAEVP--QPPGKITVDDVTRNSVSLSWT---KPEHDGGSKI 16857
Query: 1132 VGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTV 1190
+ Y ++ H + S + + I +L + EY +V A N G S P S V
Sbjct: 16858 IQYIVEMQAK--HSEKWSECARVK-SLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAV 16914
Query: 1191 VGRTRESV--PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQP 1248
++ V P P S + + EVP + R + + D P
Sbjct: 16915 PIVAKDLVIEPDVKPAFSSYSVQVGQDLKI---EVPISGRPKPTITWT-------KDGLP 16964
Query: 1249 RFWLVEGNSSRSAQLTGL----------GKYVLYEVQVLAFTRIGDGSPSHPPILERTLD 1298
N + S LT L G+Y + V +G + S +E
Sbjct: 16965 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV-----VGQKTAS----IEIVTL 17015
Query: 1299 DVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA 1357
D P PP G + F +V S+ L W PP G + I + +TTT T V A A
Sbjct: 17016 DKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTT--TVWDVVSATVA 17073
Query: 1358 R-QYTATGLKPESVYLFRITAQTRKGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
R T LK + Y FRI A+ R G A E+ +V P PP P +
Sbjct: 17074 RTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATA--ISK 17131
Query: 1416 RSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S+++ W EP ++G SPV Y ++ +E S W + ++ H+ + F L+ Y+F
Sbjct: 17132 DSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHD-TQFKAQNLEEGIEYEF 17190
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV A N +G + S+ SE P P + V + T ++W P D +
Sbjct: 17191 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEIT---LQWTKPVYDG-GSM 17246
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
+ G+ + R+L P W + S N+ TQ+ + L + +
Sbjct: 17247 ITGYIVEKRDL---------------PDGRWMKA----SFTNVIE---TQFTVSGLTEDQ 17284
Query: 1594 RYEIRMSVYNAVG--------EGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT---QLDV 1642
RYE R+ NA G GP + EV + R+ +V A T + DV
Sbjct: 17285 RYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADV 17344
Query: 1643 TWEP-PPLDSQNGDIQGYKIYFWEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSV 1700
+P P ++ GD + E+ R + K L + ++++++ +
Sbjct: 17345 HGKPLPTIEWLRGDKE-----IEESARCEIKNTDFKALLIVKDAIRI------DGGQYIL 17393
Query: 1701 AAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLV 1760
A N AG +S P + V+ + +T+ +++W +P +G + V
Sbjct: 17394 RASNVAGS--KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPLQDGGSDISHYV 17450
Query: 1761 YEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIE-ANVTT 1818
E +V +V NS LKV L EG Y FRI A + G +E A V
Sbjct: 17451 VEKRETSRLAWTVVASEVVTNS---LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLM 17507
Query: 1819 GPGEGAPGPP-GVPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDI 1876
PGPP + + ++ + W+ D G I Y++E R W IK
Sbjct: 17508 KNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW---IKCN 17564
Query: 1877 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ ++ + L Y+FRV A N G G PS
Sbjct: 17565 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17600
Score = 190 bits (482), Expect = 1e-47
Identities = 360/1569 (22%), Positives = 576/1569 (36%), Gaps = 242/1569 (15%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G + L +G P P ITW K + IL P +S ++ I + SD G
Sbjct: 7396 TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS-TVTIVDSKRSDTG 7454
Query: 472 TYTCLATNSRGVDEASADLVVWAR---------TRITK--------PPQDQSVIKGTQAS 514
TY A N G A ++ V + T +T PP+D S
Sbjct: 7455 TYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDG------GS 7508
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA 574
+ + R T +W K +T+ + +L N Y RV +
Sbjct: 7509 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKE-------------YIFRVAAE 7555
Query: 575 ---GGNDSRSAHLRVRQLPHAPEHPVATL--STVERRAINLTWTKPFD-GNSPLIRYILE 628
G + A + P P L S + + A+ LTW +P D G SP+ Y +E
Sbjct: 7556 NMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE 7615
Query: 629 MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--P 686
+ + V + K T+ VKGL + Y+FR+ A N G G+ SK TE + + P
Sbjct: 7616 RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP 7675
Query: 687 EEPPTAPPQNVIAS-GRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
+PP P + + G+T S+ + W P H G ++ Y+I G +
Sbjct: 7676 IDPPWPPGKPTVKDVGKT--SVRLNWTKP--EHDGGAKIESYVIEMLKTGTDEWVRVAE- 7730
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEA 802
LL L+ Y V A N AG S S + P PP +
Sbjct: 7731 -GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7789
Query: 803 TNSTTIRFTWNAPSPQFINGI------NQGYKLIAWEP-EQEEEVTMVTARPNFQDSIHV 855
T W P + I + + W+ + + T T P + S++V
Sbjct: 7790 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYV 7849
Query: 856 GFVS-----GLKKFTEYFTSVLC---FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
V+ G +TE SVL FTT PGP L+ ++
Sbjct: 7850 FRVAAENAIGQSDYTEIEDSVLAKDTFTT------------------PGPPYALAVVDVT 7891
Query: 908 DTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTI 966
+ + W+ P G + Y I +E T +RVT + T
Sbjct: 7892 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 7951
Query: 967 EVAAMTSKGQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSI 1023
+V A G G S T +S P P PP +L +++ G + + + ++ P +G + I
Sbjct: 7952 QVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 8011
Query: 1024 SRWLVE-AQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
+ VE VG E+W+ ++ + D + + P Y R+R VN +G S P
Sbjct: 8012 IGYHVEMCPVGT----EKWMRVNSRPIK-DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 8066
Query: 1083 SQPSRKIQTLQAPPDMAPANVSLRTAS---------ETSLWLRWMPLPEMEYNGNPESVG 1133
S+ S + + PD P + L T + R +P+P + ++ + + V
Sbjct: 8067 SEISENV--VAKDPDCKP-TIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK 8123
Query: 1134 YKIKYSRSDGHGKTLSHV-VQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVG 1192
+ + + H +H+ V V D I Y + ++ N +GS S V
Sbjct: 8124 ASDRLTMKNDH--ISAHLEVPKSVRADAGI--------YTITLE--NKLGSATASINV-- 8169
Query: 1193 RTRESVPSSGP-TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW 1251
+ + GP ++ A T SS + W E PE D +L Y + + +++ +
Sbjct: 8170 ---KVIGLPGPCKDIKASDITKSSCKLTW-EPPEFDGGTPILHY--VLERREAGRRTYIP 8223
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILF 1309
++ G + S + L Y +V A ++G G P++ + P PP+ +
Sbjct: 8224 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8283
Query: 1310 PEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPE 1368
++ + W+PP G I+ Y I E L P YTA GL+
Sbjct: 8284 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEG 8342
Query: 1369 SVYLFRITAQTRKGWGEAAEALVVT--TEKRDRPQPPSRPM--VQQEDVRARSVLLS--- 1421
Y FR+ A+ G E + A T + D P+ R V++ D A +S
Sbjct: 8343 KEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSP 8402
Query: 1422 -----WEPGSDGLSPV------------RYYTIQTRE---LPSGRWALHSASVSHNASSF 1461
W + + P R +Q E LP + S +
Sbjct: 8403 YPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLR 8462
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH-TTTSVLI 1520
+ D L+P + +K ND G +++ T+ P I V TSVL
Sbjct: 8463 VRDSLRPDHGL-YMIKVENDHG------IAKAPCTVSVLDTPGPPINFVFEDIRKTSVLC 8515
Query: 1521 RWQPPAEDKINGILLGFRIRYRELLYEGLRGFTL--RGINNPGATWAELTSMYSMRNLSR 1578
+W+PP +D + I+ +TL + P + W +TS ++R+
Sbjct: 8516 KWEPPLDDGGSEII----------------NYTLEKKDKTKPDSEWIVVTS--TLRH--- 8554
Query: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV-PTAAPRNVVVHGATA 1637
+Y + L + + Y R+ N G GP + + + P AP +V T+
Sbjct: 8555 ---CKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS 8611
Query: 1638 TQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQRGNLT--ERVKTLFLAENSVKLKNLTGYT 1694
+ V W P NG I G Y+ E + N T RV L + L
Sbjct: 8612 NSMLVKWNEP---KDNGSPILG---YWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 8665
Query: 1695 AYMVSVAAFNAAGDGPRSTPTQGQT--QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
Y+ V A NAAG G S P+ +T +P P + ++ ++T++ + WE P F G
Sbjct: 8666 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGG 8725
Query: 1753 ILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEI 1812
G + Y + G ++ K VK++ EG Y+ R+ A
Sbjct: 8726 ---GEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSA--------- 8773
Query: 1813 EANVTTGPGEGAPG------------PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860
GEG PG PP V + V I I GK V+
Sbjct: 8774 ----VNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIM-----AGKTLRIPAVVT 8824
Query: 1861 ARPSDEGLW 1869
RP +W
Sbjct: 8825 GRPVPTKVW 8833
Score = 189 bits (481), Expect = 2e-47
Identities = 331/1484 (22%), Positives = 562/1484 (37%), Gaps = 198/1484 (13%)
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTY 473
G S+ L G P P + W K G ++ + S SL++ + D+G Y
Sbjct: 16652 GGSLRLFVPIKGRPTPEVKWGK-----VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKY 16706
Query: 474 TCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTI------ 527
T NS G A + V PP + V + T+ S+ +T +P +
Sbjct: 16707 TLTLENSSGTKSAFVTVRV---LDTPSPPVNLKVTEITKDSV--SITWEPPLLDGGSKIK 16761
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAH 583
YI EK AT + + +N S I Q G +Y RV + G +++A
Sbjct: 16762 NYIVEKREATRKSYAAVVTNCHKN-SWKIDQLQEGC--SYYFRVTAENEYGIGLPAQTAD 16818
Query: 584 -LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
++V ++P P T+ V R +++L+WTKP DG S +I+YI+EM ++ A
Sbjct: 16819 PIKVAEVPQPPGK--ITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16876
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ--------FSKDTERVSLPEEPPTAP 693
V K+ + L Y FR+ AVN+ G+ +KD V P+ P
Sbjct: 16877 RV--KSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL--VIEPDVKPAFS 16932
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK-NITDADVNNL 752
+V + I +P P I + GLP+ + N+TD+ L
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPT-----------ITWTKDGLPLKQTTRINVTDS----L 16977
Query: 753 LLEDLIIWTNYEIEVAAYNSAGLGVYSSKVT--EWTLQGVPTVPPGNVHAEATNSTTIRF 810
L L I ++ + Y V K E P P G V + ++ +I
Sbjct: 16978 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITL 17037
Query: 811 TWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTS 870
+WN P G ++ + ++ + T V + + V+ LK TEY
Sbjct: 17038 SWNPPL------YTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFR 17091
Query: 871 VLCFTTPGDG--PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTG 927
+ G S P + + PGP G + I S+ + W EP G + G
Sbjct: 17092 IFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 17151
Query: 928 YRISWEEYN-----RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAS 982
Y + +E N + N + H +++ L Y V A G G+ S +
Sbjct: 17152 YHLERKERNSILWTKVNKTIIH-----DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17206
Query: 983 T--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGE 1039
+ + P + PG P + + +TLQ+ +P YDG + I+ ++VE + G
Sbjct: 17207 SECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWM 17263
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
+ + + + V L Y FR+ N G S+PS + A ++
Sbjct: 17264 KASFTNVIETQ-----FTVSGLTEDQRYEFRVIAKNAAGAI--SKPSDSTGPITAKDEVE 17316
Query: 1100 PANVSLR---------TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKT 1147
+S+ A ET + PLP +E+ + + + + K
Sbjct: 17317 LPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKA 17376
Query: 1148 LSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVS 1207
L +V+D + D + ++A N GS + V R P GP V+
Sbjct: 17377 LL-IVKDAIRIDGG----------QYILRASNVAGSKSFPVNVKVLDRPG-PPEGPVQVT 17424
Query: 1208 ALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS--SRSAQLTG 1265
+ TS + WS P G + + V+ K +T W V + + S ++T
Sbjct: 17425 GV--TSEKCSLTWS--PPLQDGGSDISHYVVEKR---ETSRLAWTVVASEVVTNSLKVTK 17477
Query: 1266 LGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
L + Y +++A + G G P P+L + +PGPP + + S+ + W P
Sbjct: 17478 LLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRP 17537
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
+ G + I + + + + + TGL + Y FR++A+ G G
Sbjct: 17538 DSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 17597
Query: 1385 EAAEALVV--TTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRE 1441
E + A V + +P PP+ + D S+ L+W +P DG S + Y ++ +
Sbjct: 17598 EPSPATVYYKACDPVFKPGPPTNAHIV--DTTKNSITLAWGKPIYDGGSEILGYVVEICK 17655
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
W + + + F + +L YK RV A N +G E + S T
Sbjct: 17656 ADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTVKPEDK 17713
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
EAP L + +++R A I +G P
Sbjct: 17714 LEAPE-LDLDSELRKGIVVRAGGSARIHI----------------------PFKGRPTPE 17750
Query: 1562 ATWAELTSMYS--MRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
TW+ ++ ++ + TQ +DN +++ + + + N+ G S V V
Sbjct: 17751 ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG----SKSAFVTVK 17806
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR---GNLTERVK 1676
P+N+ V + WEPP +D ++ Y I E+ R N++ +
Sbjct: 17807 VLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDG-GAKVKNYVIDKRESTRKAYANVSSK-- 17863
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELT 1736
++ S K++NLT Y V A N G G PS P V ++++
Sbjct: 17864 ---CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17920
Query: 1737 TTSVNVSWEAPQFPNGI-LEGYRLVYEPCS----PVDGVSKIVTVDVKGNSPLWLKVKDL 1791
TS ++ WE P+ G + GY + +P + SK+ V G L
Sbjct: 17921 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTG----------L 17970
Query: 1792 AEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
+ G Y+FR++A Y + G+ P GVP+I +
Sbjct: 17971 SSGQEYQFRVKA----YNEK---------GKSDPRVLGVPVIAK 18001
Score = 189 bits (479), Expect = 3e-47
Identities = 429/1885 (22%), Positives = 716/1885 (37%), Gaps = 273/1885 (14%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAGR 180
V GE I P + P P V+W +DG+++ S R+ + ++ L + +V DAG
Sbjct: 8093 VIEGEKLSIPVP-FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGI 8151
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN 240
Y + N K G S I + V + GP I K + + + ++T E
Sbjct: 8152 YTITLEN-KLGSATAS--INVKVIGLPGPCKDI--------KASDITKSSCKLTWEPPEF 8200
Query: 241 ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVL-------RSSSV 293
LH + ++ + RR IP +G + + + ++ R +V
Sbjct: 8201 DGGTPILHYVLER---------REAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8251
Query: 294 PSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW----YKDAAVV 349
V G Y+ L+ P ++P++ + VD+ +ITW Y + +
Sbjct: 8252 NKVGGGEYIE-LKNPVIAQDPKQ----PPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8306
Query: 350 E---VEKLTRFRQR----NDGGLQI-----SGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
+EK+ + +R N+ + I GL F+ A NAAG + S
Sbjct: 8307 MGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPP 8366
Query: 398 TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLES 457
T I D V+L R ++ ++G+ I S+ S
Sbjct: 8367 TKAVDPI----------DAPKVIL--------RTSLEVKRGDEIALDASI---------S 8399
Query: 458 GSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVC 517
GS + T I D + + +A LV + + + ++ V+ TQ
Sbjct: 8400 GSPYPTITWIKDENVIV-----PEEIKKRAAPLVRRRKGEVQE--EEPFVLPLTQ----- 8447
Query: 518 GVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGN 577
R++I D + G ES R+R + D G Y +V + G
Sbjct: 8448 ------RLSI------DNSKKG-ESQLRVR----------DSLRPDHGLYMIKVENDHGI 8484
Query: 578 DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP- 635
+ V P P + V + + ++ W P D G S +I Y LE + P
Sbjct: 8485 AKAPCTVSVLDTPGPPINFV--FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPD 8542
Query: 636 --WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL-PEEPPTA 692
W V+ +++ SVT L+ + Y FR+ A N G G V+ P PP A
Sbjct: 8543 SEWIVVTSTLRHCKYSVTK--LIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8600
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNL 752
P + ++ +N S++++W P + NG I+ Y L V + + + N
Sbjct: 8601 PDKPIVEDVTSN-SMLVKWNEPKD---NG---SPILGYWLEKREVNSTHWSRVNKSLLNA 8653
Query: 753 L---LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV--HAEATNSTT 807
L ++ L+ Y V A N+AG G +S T P PPG T+STT
Sbjct: 8654 LKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTT 8712
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTAR-PNFQDSIHVGFVSGLKKFTE 866
I W P+ N G +++ + +++ T +R + V +++ +
Sbjct: 8713 IELEWEPPA------FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGAD 8766
Query: 867 YFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKN---- 922
Y V G+GP Q V E P L D S+K Q K
Sbjct: 8767 YKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVEL------DVSVKGGIQIMAGKTLRIP 8820
Query: 923 GILTGYRIS---W--EEYNRTNTRVTHYLPNVTLEYRVTGLTALTT-YTIEVAAMTSKGQ 976
++TG + W EE RV + NV + + AL + V T+
Sbjct: 8821 AVVTGRPVPTKVWTKEEGELDKDRVV--IDNVGTKSELIIKDALRKDHGRYVITATNSCG 8878
Query: 977 GQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVV 1035
+ +A+ + ++PGP +L + L + P DG + I+ +++E + +
Sbjct: 8879 SKFAAARVEVF---DVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 8935
Query: 1036 GEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP 1095
+ + E + ++ L Y FR+ N G PP + +
Sbjct: 8936 HTWRQPI-------ETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLG 8988
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
P +P ++ +++++ L W E NG GY I+ R H K V R
Sbjct: 8989 PPTSPERLTYTERTKSTITLDWK---EPRSNGGSPIQGYIIEKRR---HDKPDFERVNKR 9042
Query: 1156 V--ERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGPTNVSALATT 1212
+ + +E+L+E Y +V+A N IG S P V + VP PT L+
Sbjct: 9043 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP---PTIKLRLSVR 9099
Query: 1213 SSSMLVRWSE---VPEADRNGLVLGYKVMYKEKDSDTQPR--FWLVEGNSSRSAQLTGLG 1267
++ V+ E +P AD GL + K + +P + + SRS T L
Sbjct: 9100 GDTIKVKAGEPVHIP-ADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 9158
Query: 1268 --KYVLYE---VQVLAFTRIGDGSPS-HPPILERTLDDVPGPPMGILFPEVRTTSVRLIW 1321
K V + V A R+G + H + +R P PP + +++ S L W
Sbjct: 9159 IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDR-----PSPPRNLAVTDIKAESCYLTW 9213
Query: 1322 QPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA-RQYTATGLKPESVYLFRITAQTR 1380
P G + + + + + + EV + ++Y L P Y FR+ A +
Sbjct: 9214 DAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNK 9273
Query: 1381 KGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQ 1438
G + ++ VV + P PP +P V S+L+SW P D G SP+ Y ++
Sbjct: 9274 YGISDECKSDKVVIQDPYRLPGPPGKPKVLART--KGSMLVSWTPPLDNGGSPITGYWLE 9331
Query: 1439 TRELPSGRWALHSAS----VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE-S 1493
RE S W+ S + V F V RL Y+FR A N G SE S+
Sbjct: 9332 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPE 9391
Query: 1494 LTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT 1553
+ P P+ V T +S+ + W+PPA+D + I G+ + +E EG +
Sbjct: 9392 VAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIK-GYIVEMQE---EGTTDW- 9446
Query: 1554 LRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSP 1612
+ +N P + + NL + R+Y R+ N GE PS
Sbjct: 9447 -KRVNEPDKLITTCECV---------------VPNLKELRKYRFRVKAVNEAGESEPSDT 9490
Query: 1613 PQEVFVGEA-------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
E+ + + A +V + ++ + P + + G +
Sbjct: 9491 TGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMK 9550
Query: 1666 AQRGNLTERVKTLFLAENSVKL------KNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQT 1719
++ E + L AENS + ++ TG S+ A N AG + T
Sbjct: 9551 DGVHDIPEDAQ-LETAENSSVIIIPECKRSHTG----KYSITAKNKAG---QKTANCRVK 9602
Query: 1720 QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDV 1778
P P +K S++T S +SW+ P G ++GY + +DG +
Sbjct: 9603 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT---IDGKAWTKVNPD 9659
Query: 1779 KGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEA-NVTTGPGEGAPGPPGVPIIVRY 1836
G++ V DL Y FR+RA+ F GP +E TT P P + + +
Sbjct: 9660 CGSTTF--VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9717
Query: 1837 SSAIAIHWSSGDP---GKGPITRYVIEARPSD-----EGLWDILIKDIPKEVSSYTFSMD 1888
+ +H S P G P+T Y++E D + W K ++V F+++
Sbjct: 9718 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK---RDVEELQFTVE 9774
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSS 1913
L G Y+FRV AVN G PS+
Sbjct: 9775 DLVEGGEYEFRVKAVNAAGVSKPSA 9799
Score = 187 bits (474), Expect = 1e-46
Identities = 315/1447 (21%), Positives = 553/1447 (38%), Gaps = 151/1447 (10%)
Query: 524 RVTIRYIWEKDGATLGTESHPRIRLDRNGSL-HISQTWSGDIGTYTCRVISAGGNDSRSA 582
R T W KD L + N SL I D+G Y ++ ++ G +
Sbjct: 15869 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL 15928
Query: 583 HLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLL 640
++ V P P PV + V +I L+W P +DG S + YI+E + + W ++
Sbjct: 15929 NVIVLDKPGPPTGPVK-MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15987
Query: 641 ASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIAS 700
A+V T++ L YQFR+ A N GK + V+ PP + +
Sbjct: 15988 ATV--ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 16045
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIW 760
+ S+ +QW P + ++ ++ R + + N T L
Sbjct: 16046 LSSRDSMEVQWNEPISDGGSRVIGYHLERK--ERNSILWVKLNKTPIPQTKFKTTGLEEG 16103
Query: 761 TNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFI 820
YE V+A N G+G SKV+E + P PPG A ++ W P+
Sbjct: 16104 VEYEFRVSAENIVGIGK-PSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPT---- 16158
Query: 821 NGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG- 878
+ G K+ + E++E + +F + I F V+GL + Y V+ G
Sbjct: 16159 --YDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 16216
Query: 879 -DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNR 937
P + + ++V P +S ++ V E + + + G I ++ +
Sbjct: 16217 FSEPSESTGAITARDEVDPP--RISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK 16274
Query: 938 TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL----- 992
+ +++ T + T+ +++ A G + A ++ +
Sbjct: 16275 GDQELSN-----TARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 16329
Query: 993 --PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP + IS + TL ++P DG + I ++VE + L+ +
Sbjct: 16330 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRE------TSRLVWTVVD 16383
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTA 1108
S +V L Y+FR+ VN G P + + AP + T
Sbjct: 16384 ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV 16443
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLE 1166
++ S+ + W +G E +GY ++ +G T H R+ E + L
Sbjct: 16444 TKDSMIVVW---ERPASDGGSEILGYVLEKRDKEGIRWTRCH---KRLIGELRLRVTGLI 16497
Query: 1167 EWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLVRWSEVP 1224
E +Y +V A NA G S P + + + + GP N + T SS+ + WS+ P
Sbjct: 16498 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK-P 16556
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV----EGNSSRSAQLTGLGKYVLYEVQVLAFT 1280
D + GY V + D W + G + + ++ L + Y ++ A
Sbjct: 16557 IYDGGCEIQGYIV----EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16612
Query: 1281 RIGDGSPSHPP---ILERTLDDVPGPPMGILFPEVRTT----SVRLIWQPPAAPNGIILA 1333
+ G G + P I+E L+ P + + ++ S+RL P +
Sbjct: 16613 KAGVGEHADVPGPIIVEEKLE-APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 16671
Query: 1334 YQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY---LFRITAQTRKGWGEAAEAL 1390
++ + + A ++V + +T+ L + Y + +T + G ++
Sbjct: 16672 GKVDGEIR----DAAIIDVTS----SFTSLVLDNVNRYDSGKYTLTLENSSG----TKSA 16719
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
VT D P PP V + + SV ++WEP DG S ++ Y ++ RE +A
Sbjct: 16720 FVTVRVLDTPSPPVNLKVTE--ITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16777
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
+ N S+ +D+L+ SY FRV A N+ G ++ ++ + + + P ++
Sbjct: 16778 VVTNCHKN--SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVP--QPPGKIT 16833
Query: 1510 VTPHTTTSVLIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE 1566
V T SV + W P D KI ++ + ++ E W+E
Sbjct: 16834 VDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-------------------KWSE 16874
Query: 1567 LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-------PSSPPQEVFVG 1619
+ S+ Q + NL + Y R+ N G P V
Sbjct: 16875 CARVKSL---------QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 16925
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF 1679
+ P + +V V ++ ++ P P + D K + R N+T+ +L
Sbjct: 16926 DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK----QTTRINVTD---SLD 16978
Query: 1680 LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTS 1739
L S+K + Y ++VA N G S + P P VKF +++ S
Sbjct: 16979 LTTLSIKETHKDDGGQYGITVA--NVVGQKTASIEIVTLDKPDPPKGP--VKFDDVSAES 17034
Query: 1740 VNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1799
+ +SW P + G + + + V +V+ V + LKV L G Y+F
Sbjct: 17035 ITLSWNPPLYTGGC-QITNYIVQKRDTTTTVWDVVSATVARTT---LKVTKLKTGTEYQF 17090
Query: 1800 RIRAKTF---TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGKGPI 1854
RI A+ ++ E + V P + PGPPG P S ++ I W + G P+
Sbjct: 17091 RIFAENRYGQSFALESDPIVAQYPYK-EPGPPGTPFATAISKDSMVIQWHEPVNNGGSPV 17149
Query: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSP 1914
Y +E + + LW + K I + F L+ G+ Y+FRV A N G G S
Sbjct: 17150 IGYHLERKERNSILWTKVNKTI---IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17206
Query: 1915 SQSVPAQ 1921
S+ A+
Sbjct: 17207 SECYVAR 17213
Score = 177 bits (449), Expect = 1e-43
Identities = 352/1605 (21%), Positives = 600/1605 (37%), Gaps = 162/1605 (10%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP-------LDSTVI--DGM 417
+SGL D F+ A+NAAG + + + + P TVI G
Sbjct: 15113 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 15172
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ L + SG P P + W K + L G+ +L S +L+ + D+G YT A
Sbjct: 15173 AFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 15231
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP-------RVTIRYI 530
TN G + ++ V R PP+ + S C ++ P ++ +
Sbjct: 15232 TNPGGFAKHIFNVKVLDRPG---PPEGPLAVTEV-TSEKCVLSWFPPLDDGGAKIDHYIV 15287
Query: 531 WEKDGATLG-TESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA---GGNDSRSAHLRV 586
+++ + L T +++ + L +++ G+ Y RV++ G + + +
Sbjct: 15288 QKRETSRLAWTNVASEVQVTK---LKVTKLLKGN--EYIFRVMAVNKYGVGEPLESEPVL 15342
Query: 587 RQLPHAPEHPVAT--LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
P+ P P ++T+ + ++ + W P DG S +I YI+E + +
Sbjct: 15343 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15402
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVG------KGQFSKDTERVSLPEEPPTAPPQNV 697
V GL Y+FR+ A N G F K + V P PP N
Sbjct: 15403 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKP-----GPPGNP 15457
Query: 698 IASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA---DVNNLLL 754
+ SI I W P + I GY++ L P +++ +T + +
Sbjct: 15458 RVLDTSRSSISIAWNKPIYDGGSEIT-GYMVEIAL---PEEDEWQIVTPPAGLKATSYTI 15513
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
L Y+I + A NS GLG + T + + P + +A +
Sbjct: 15514 TGLTENQEYKIRIYAMNSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACC 15571
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT--EYFTSVL 872
F+ + + W + E + + ++ + V + +F +Y +V
Sbjct: 15572 TLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI--VGNVNRFDSGKYILTV- 15628
Query: 873 CFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS 931
G +S VR D PGP L E+ TS+ ++W P G + Y +
Sbjct: 15629 ---ENSSGSKSAFVNVRVL-DTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE 15684
Query: 932 WEEYNR-------TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
E R TN T ++V L +Y V A G G + A T
Sbjct: 15685 KRESTRKAYSTVATNCHKT--------SWKVDQLQEGCSYYFRVLAENEYGIG-LPAETA 15735
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
S E P PP + + ++ SV+L + +P +DG + I ++VE Q ++W
Sbjct: 15736 ESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQ---TKGSDKWAT 15792
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPA 1101
+ + L YSFR+ N G S P Q S + + L PP
Sbjct: 15793 CATVK----VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLL 15848
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD-- 1159
+ + L + ++ + G P + + + + K + V + E +
Sbjct: 15849 FNTFTVLAGEDLKV------DVPFIGRPTPA---VTWHKDNVPLKQTTRVNAESTENNSL 15899
Query: 1160 YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR 1219
TI+D V+ N+ G + V+ + P +GP + + T+ S+ +
Sbjct: 15900 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG-PPTGPVKMDEV--TADSITLS 15956
Query: 1220 WSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYVLYEVQVLA 1278
W P+ D + Y V EK + + +V +R+ + L Y+ ++ A
Sbjct: 15957 WGP-PKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAA 16012
Query: 1279 FTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQ 1335
R G + S P + + VPGPP + S+ + W P + G ++ Y
Sbjct: 16013 ENRYGKSTYLNSEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYH 16071
Query: 1336 ITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTE 1395
+ + + + P + + TGL+ Y FR++A+ G G+ ++
Sbjct: 16072 LERKERNSILWVKLNKTPIPQTK-FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYV- 16129
Query: 1396 KRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASV 1454
RD PP RP + V SV L W +P DG S + Y ++ +ELP GRW + ++
Sbjct: 16130 ARDPCDPPGRP--EAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRW-MKASFT 16186
Query: 1455 SHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHT 1514
+ + F V L Y+FRV A N G FSE SES + A + P +S+ P
Sbjct: 16187 NIIDTHFEVTGLVEDHRYEFRVIARNAAG--VFSEPSESTGAITARDEVDPPRISMDPKY 16244
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-FTLRGINNPGATWAELTSMYSM 1573
++++ K++ + G I + ++G L + + S+
Sbjct: 16245 KDTIVV--HAGESFKVDADIYGKPIP----TIQWIKGDQELSNTARLEIKSTDFATSLSV 16298
Query: 1574 RNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVH 1633
++ R Y L N + ++V GP P VV+
Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGP----------------VVIS 16342
Query: 1634 GATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGY 1693
G TA + + W+ PPL DI Y + E R L V + S K+ L
Sbjct: 16343 GVTAEKCTLAWK-PPLQDGGSDIINYIVERRETSR--LVWTVVDANVQTLSCKVTKLLEG 16399
Query: 1694 TAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPN 1751
Y + A N G G S P + P AP + + + +T S+ V WE P
Sbjct: 16400 NEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDG 16459
Query: 1752 GI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT--- 1807
G + GY L + + + L L+V L E Y FR+ A+
Sbjct: 16460 GSEILGYVLEKRDKEGI----RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLS 16515
Query: 1808 -YGPEIEANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPS 1864
P P PGPP P ++ + S++ + WS G I Y++E
Sbjct: 16516 EPSPPSAYQKACDP-IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 16574
Query: 1865 DEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G W + P ++ ++ L Y+FR+ A+N G G
Sbjct: 16575 SVGEWTMCTP--PTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16617
Score = 177 bits (449), Expect = 1e-43
Identities = 292/1333 (21%), Positives = 502/1333 (37%), Gaps = 167/1333 (12%)
Query: 647 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGR-TNQ 705
+T++ K S + L A N G F+K V + + P PP+ +A T++
Sbjct: 15211 STNLVNKDSTRRDSGAYTLTATNP---GGFAKHIFNVKVLDRP--GPPEGPLAVTEVTSE 15265
Query: 706 SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNNLLLEDLIIWTNYE 764
++ W PP + + YI++ + N+ ++ V L + L+ Y
Sbjct: 15266 KCVLSWFPPLDDG-GAKIDHYIVQKRETSR---LAWTNVASEVQVTKLKVTKLLKGNEYI 15321
Query: 765 IEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFING 822
V A N G+G + S V G P PP N ++ W P
Sbjct: 15322 FRVMAVNKYGVGEPLESEPVLAVNPYGPPD-PPKNPEVTTITKDSMVVCWGHPDS----- 15375
Query: 823 INQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-DG 880
+ G ++I + E+ ++ + N + + + VSGL + EY ++ G
Sbjct: 15376 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15434
Query: 881 PRSTPQLVRTHEDV--PGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR 937
P T + + V PGP G+ + +S+ ++W +P G +TGY +
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15494
Query: 938 TNTRVTHYLPNVTLE---YRVTGLTALTTYTIEVAAMTSKGQGQVSA-----STISSGVP 989
++ P L+ Y +TGLT Y I + AM S+G G+ + +P
Sbjct: 15495 DEWQIV--TPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 15552
Query: 990 PELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
PE+ + I F P +W + GE + I S+
Sbjct: 15553 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH-----GESLDKASIESTSS 15607
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
+ V ++N F + + N G+ R + T P D+ ++ +
Sbjct: 15608 YT---LLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDL-----KVKEVT 15659
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
+TS+ L W P P ++ G + Y ++ + + K S V + + + ++ L+E
Sbjct: 15660 KTSVTLTWDP-PLLD--GGSKIKNYIVE--KRESTRKAYSTVATNCHKTSWKVDQLQEGC 15714
Query: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSG----PTNVSALATTSSSMLVRWSEVPE 1225
Y +V A N G G + T ESV +S P ++ + T +S+ + W E PE
Sbjct: 15715 SYYFRVLAENEYGIG-----LPAETAESVKASERPLPPGKITLMDVTRNSVSLSW-EKPE 15768
Query: 1226 ADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDG 1285
D +LGY V + K SD V+ A +TGL + Y +V A G
Sbjct: 15769 HDGGSRILGYIVEMQTKGSDKWATCATVKVTE---ATITGLIQGEEYSFRVSAQNEKGIS 15825
Query: 1286 SPSH------------PP---ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
P PP +L T + G + + P + + + W P
Sbjct: 15826 DPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVP--- 15882
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ T R+N + ++ + + R+ Y+ ++T GEA E L
Sbjct: 15883 ---LKQTTRVNAESTENNSLLTIKDACREDVGH-------YVVKLTNSA----GEAIETL 15928
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
V D+P PP+ P V+ ++V A S+ LSW P DG S + Y ++ R+ + W +
Sbjct: 15929 NVIV--LDKPGPPTGP-VKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQI 15985
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
SA+V+ ++ RLK Y+FR+ A N G S + ++ P
Sbjct: 15986 VSATVAR--TTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV 16043
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + S+ ++W P D + ++ G+ L W +L
Sbjct: 16044 VTLSSRDSMEVQWNEPISDGGSRVI----------------GYHLERKERNSILWVKL-- 16085
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE--AVPTAAP 1627
N + T+++ L + YE R+S N VG G S E +V P P
Sbjct: 16086 -----NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRP 16140
Query: 1628 RNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKL 1687
++V T + + W+ P D I GY + E G + T + + ++
Sbjct: 16141 EAIIV---TRNSVTLQWKKPTYDG-GSKITGYIVEKKELPEGRWMKASFTNII-DTHFEV 16195
Query: 1688 KNLTGYTAYMVSVAAFNAAGDGPRSTPTQG----QTQQAAPSAPSSVKFSELTTTSVNVS 1743
L Y V A NAAG + + G + + P K+ + S
Sbjct: 16196 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 16255
Query: 1744 WEAPQFPNGILEGYRLVYEPCSPVDGV------SKIVTVDVKGNS-PLWLKVKDLAEGVT 1796
++ G +P + + S +++K L VKD +
Sbjct: 16256 FKVDADIYG---------KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16306
Query: 1797 YRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGKGP 1853
+ ++AK + NV PGPP P+++ +A + W G
Sbjct: 16307 GNYILKAKNVAGERSVTVNVKV---LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSD 16363
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSS 1913
I Y++E R + +W + + V + + + L G Y FR++AVN YG G
Sbjct: 16364 IINYIVERRETSRLVWTV----VDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG---E 16416
Query: 1914 PSQSVPAQKANPF 1926
P +S P NPF
Sbjct: 16417 PLESEPVVAKNPF 16429
Score = 171 bits (433), Expect = 7e-42
Identities = 352/1639 (21%), Positives = 604/1639 (36%), Gaps = 203/1639 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL--------DSTVIDGM 417
+++ L D F+ FARNAA V + I + P D V+
Sbjct: 19440 EVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAG 19499
Query: 418 SVV-LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ + + +G P P I+W K + I + + L + D G Y
Sbjct: 19500 EVLKINADIAGRPLPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19558
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
N G + + V + PP I G A C ++ W +
Sbjct: 19559 LKNVAGTRSVAVNCKVLDKPG---PPAGPLEINGLTAEK-CSLS----------WGRPQE 19604
Query: 537 TLGTESHPRIRLDRNGSLHISQT-WSGDIGTYTCRVIS-----------------AGGND 578
G + I +++ + H++ T G++ +C+V G
Sbjct: 19605 DGGADIDYYI-VEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19663
Query: 579 SRSAHLRVRQLPHAPEHPVAT-LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPW 636
S ++ P P + +++V + ++ L W++P DG S + YI+E E N+
Sbjct: 19664 LESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLR 19723
Query: 637 TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT------ERVSLPEEPP 690
V + V GL Y++R+ A N G S+ + + V LP PP
Sbjct: 19724 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPS-PP 19782
Query: 691 TAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
+ P ++ SG+T +I I W P + GY + Y K D D
Sbjct: 19783 SKP--KIVDSGKT--TITIAWVKPLFDG-GAPITGYTVEY-----------KKSDDTDWK 19826
Query: 751 NLL---------LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAE 801
+ + L Y V + N G S + P ++ +E
Sbjct: 19827 TSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 19886
Query: 802 ATNSTTIR----FTWNAPS-----PQFI-NGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851
+ ++ FT P P + + + + A+ + ++ N D
Sbjct: 19887 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRND 19946
Query: 852 SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
S K+T +VL ++ LV D PGP +++ ++ S
Sbjct: 19947 S---------GKYTLTIQNVLS--------AASLTLVVKVLDTPGPPTNITVQDVTKESA 19989
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTN-TRVTHYLPNVTLEYRVTGLTALTTYTIEVA 969
+SW P G + Y I E ++ VT+ L Y+VT L Y V+
Sbjct: 19990 VLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNR--LSYKVTNLQEGAIYYFRVS 20047
Query: 970 AMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLV 1028
G G + A T E P PP LG+++I SV+L + +P +DG + I ++V
Sbjct: 20048 GENEFGVG-IPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVV 20106
Query: 1029 EAQVGVVGEGEE-WLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSR 1087
EA + +G++ W+ + V L + Y FR+ N G S P +
Sbjct: 20107 EA----LEKGQKNWVKCAVAKSTHHV----VSGLRENSEYFFRVFAENQAGLSDPRE--- 20155
Query: 1088 KIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY--NGNPESVGYKIKYSRSDGHG 1145
+ + + P + ++ ++++R +++ +G P K+ SR
Sbjct: 20156 LLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLP---KVTLSRDGVPL 20212
Query: 1146 KTLSHVVQDRVERDYTIEDLEEWTEY--RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP 1203
K + + TI E T R ++ A N+ G+ +V R P +GP
Sbjct: 20213 KATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG-PPTGP 20271
Query: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 1263
+S + T S+ ++W E P+ D V Y ++ +E + +
Sbjct: 20272 VVISDI--TEESVTLKW-EPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 20328
Query: 1264 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD-DVPGPPMGILFPEVRTTSVRLIWQ 1322
G+ Y+ ++ A R G + L PGPP V S+ + W
Sbjct: 20329 LTTGEE--YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWH 20386
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
P + G + + + L + T + +Y FR+ A+ G
Sbjct: 20387 EPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAG 20446
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRE 1441
G+ + D +PP V+ D+ SV LSW+ P DG S + Y ++ R+
Sbjct: 20447 VGKPSHPSEPVLAI-DACEPPRN--VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRD 20503
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
LP GRW S + + + FI+ L + Y+FRV A N +G S SE + +
Sbjct: 20504 LPDGRWTKASFT-NVTETQFIISGLTQNSQYEFRVFARNAVGS--ISNPSEVVGPITCID 20560
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
++ + P T V ++YR LR + G P
Sbjct: 20561 SYGGPVIDL-PLEYTEV--------------------VKYRAGTSVKLRA-GISGKPAPT 20598
Query: 1562 ATW------AELTSMYSMRNLSR-PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ 1614
W + ++ + N + S+ + D LN YE+++ NA+G ++
Sbjct: 20599 IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-YELKLR--NAMGSASATIRV 20655
Query: 1615 EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTER 1674
++ + + P P + TA ++ + W PP D G KI + ++ +
Sbjct: 20656 QI-LDKPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITHYIVEKRETSRV 20706
Query: 1675 VKTLF---LAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSS 1729
V ++ L E + + Y+ V A N G G S + P P
Sbjct: 20707 VWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 20766
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ +++T S+ V W P G + GY L + G K++ ++ KV
Sbjct: 20767 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIRDTRQ---KV 20822
Query: 1789 KDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGPPGVPIIVRYS----SAIAIH 1843
L E Y++R+ A GP E + + PPG P +R + S+I +
Sbjct: 20823 TGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID-PPGPPAKIRIADSTKSSITLG 20881
Query: 1844 WSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
WS G +T YV+E R +E W + EV + + + LKPGV+Y FRV A
Sbjct: 20882 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTV--STKGEVRTTEYVVSNLKPGVNYYFRVSA 20939
Query: 1903 VNDYGFGTPSSPSQSVPAQ 1921
VN G G P ++ V A+
Sbjct: 20940 VNCAGQGEPIEMNEPVQAK 20958
Score = 167 bits (423), Expect = 1e-40
Identities = 305/1309 (23%), Positives = 495/1309 (37%), Gaps = 158/1309 (12%)
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+++ + P PE T ++ + +++LTW KP DG S ++ Y++E E V A
Sbjct: 20064 VKITEKPSPPEKLGVT--SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAV 20121
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPE--EPPTAPPQN---- 696
K+T V GL Y FR+ A N G + V + E EPP +N
Sbjct: 20122 A--KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 20179
Query: 697 ---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLL 753
V A I I +P P+ + G+P+ + T+ NL
Sbjct: 20180 TVYVRAGSNLKVDIPISGKPLPK-----------VTLSRDGVPLKATMRFNTEITAENLT 20228
Query: 754 --LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
L++ + E+ A NS+G + G PT P V ++
Sbjct: 20229 INLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP---VVISDITEESVTLK 20285
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEE----EVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W P +G +Q I + E EV+ AR + V L EY
Sbjct: 20286 WEPPK---YDGGSQVTNYILLKRETSTAVWTEVSATVARTMMK-------VMKLTTGEEY 20335
Query: 868 FTSVLCFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
+ G D S V+ PGP + + S+ V W EP G
Sbjct: 20336 QFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSA 20395
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
+ GY + ++ N + + L T ++VT ++A Y V A + G G+ S +
Sbjct: 20396 VVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPS- 20454
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ + PP N+ I++I SV+L ++ P +DG + I+ ++VE + G +
Sbjct: 20455 EPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTK--- 20511
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQ---PSRKIQTLQAPPDMA 1099
+N + + + + L + Y FR+ N VG+ S PS+ P I + P
Sbjct: 20512 -ASFTNVTETQFI-ISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20569
Query: 1100 PANVS--LRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE 1157
P + ++ + TS+ LR +G P I++ + D +T + V +
Sbjct: 20570 PLEYTEVVKYRAGTSVKLR------AGISGKPAPT---IEWYKDDKELQTNALVCVENTT 20620
Query: 1158 --RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTV-VGRTRESVPSSGPTNVSALATTSS 1214
I+D + +++ NA+GS S T+ V + P GP +
Sbjct: 20621 DLASILIKDADRLNSGCYELKLRNAMGSA--SATIRVQILDKPGPPGGPIEFKTVTAEKI 20678
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTG--LGKYVLY 1272
++L R P AD G + + ++ K + S W + +T + K Y
Sbjct: 20679 TLLWR----PPADDGGAKITHYIVEKRETSRV---VWSMVSEHLEECIITTTKIIKGNEY 20731
Query: 1273 EVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI- 1330
+V A + G G P ++ + PGPP ++ S+ ++W P A G
Sbjct: 20732 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 20791
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA- 1389
I Y + R + ++ RQ TGL S Y +R+ A G G +E
Sbjct: 20792 ISGYFLEKRDKKSLGWFKVLKETIRDTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPS 20850
Query: 1390 -LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW 1447
+ D P PP++ ++ D S+ L W +P DG S V Y ++ R+ W
Sbjct: 20851 EFYKAADPIDPPGPPAK--IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEW 20908
Query: 1448 ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
S + ++V LKP +Y FRV A N G E E +E + EAP I
Sbjct: 20909 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL--EAPEI 20966
Query: 1508 LSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE- 1566
+ TSV+ + ED +L+ F +G P TW +
Sbjct: 20967 -DLDVALRTSVIAK---AGEDV--QVLIPF-----------------KGRPPPTVTWRKD 21003
Query: 1567 -----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEA 1621
+ YS+ N SL N +Y +++ N VGE P S V V +
Sbjct: 21004 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY--ILTIENGVGE-PKSSTVSVKVLD- 21059
Query: 1622 VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF-- 1679
P A + V H + T + + W+PP +D G I + ++ + T+R ++
Sbjct: 21060 TPAACQKLQVKHVSRGT-VTLLWDPPLIDG------GSPIINYVIEKRDATKRTWSVVSH 21112
Query: 1680 -LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ S KL +L+ T + V A N G G T+ P+ + + T T
Sbjct: 21113 KCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKT 21172
Query: 1739 SVNVSWEAPQFPNGILEGYRLVY-----EPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAE 1793
SV +SW P F G + +V E G+SK ++ V L E
Sbjct: 21173 SVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIE----------VSQLKE 21222
Query: 1794 GVTYRFRIRAKT-------FTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
FR+ AK T GP + P PG + VR
Sbjct: 21223 QSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR 21271
Score = 164 bits (414), Expect = 1e-39
Identities = 332/1511 (21%), Positives = 556/1511 (36%), Gaps = 169/1511 (11%)
Query: 473 YTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRY--- 529
+ A N +G+ + + + I P D S I G Q ++ G H+ + + Y
Sbjct: 21228 FRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIG--HNVHLELPYKGK 21285
Query: 530 -----IWEKDGATLGTESHPRIRLDRNG-SLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
W KDG L R N +L I G YT + +A +
Sbjct: 21286 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPIT 21345
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP-WTVLLA 641
+ P P+ P+ ++ ++ L+W P D G + Y +E E + W ++ +
Sbjct: 21346 VITLGPPSKPKGPIR-FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21404
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
SV T+ V LV YQFR+ A N G Q + V+ + PP +
Sbjct: 21405 SV--ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYN 21462
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T+ + + W P + + ++ + + +Q N + L+
Sbjct: 21463 VTSDGMSLTWDAPVYDGGSEVTGFHVEKK--ERNSILWQKVNTSPISGREYRATGLVEGL 21520
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
+Y+ V A NSAGL S +++TL P PPG TI WN P
Sbjct: 21521 DYQFRVYAENSAGLSSPSDP-SKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLR---- 21575
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-- 878
+ G K++ + E+ + R NF D + V+GL Y ++ G
Sbjct: 21576 --DGGSKIVGYSIEKRQGNER-WVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI 21632
Query: 879 DGPRSTPQLVRTHEDVPGPV---GHLSFSEIL---DTSLKVSWQEPGEKNGILTGYRISW 932
P + ++ T ++ P+ G F ++ SL++ G +T ++
Sbjct: 21633 SPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGV 21692
Query: 933 EEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R N +T L + +L R YT+E A + G + P ++
Sbjct: 21693 EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE--AKNASGSAKAEIKVKVQDTPGKV 21750
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
GP + +NI +TL + P DG I+ +++E + W LI ++
Sbjct: 21751 VGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRET---SRLAWALIE---DKC 21801
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1111
+A+S L Y FR+ VN G P + +Q AP +
Sbjct: 21802 EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGN 21861
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLEEWT 1169
S+ L W E +G E Y ++ R + V+ R E + + L E
Sbjct: 21862 SITLTWA---RPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRFKVTGLTEGN 21916
Query: 1170 EYRVQVQAFNAIGSGPWSQ-TVVGRTRESV-PSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
EY V A NA G GP S + + + RE V P PT V T+ +++ + WS+ P D
Sbjct: 21917 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK-PVFD 21975
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++GY + + D + E +T L Y+ +V A G G
Sbjct: 21976 GGMEIIGYIIEMCKADLGDWHKV-NAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDS 22034
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ-------ITHRL 1340
+ +D + P + I +T VR A + +AYQ + +
Sbjct: 22035 CEVTGTIKAVDRLTAPELDIDANFKQTHVVRA-----GASIRLFIAYQGRPTPTAVWSKP 22089
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + A + S T + +T + G ++++ T + D P
Sbjct: 22090 DSNLSLRADIHT-TDSFSTLTVENCNRNDAGKYTLTVENNSG----SKSITFTVKVLDTP 22144
Query: 1401 QPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP + +DV S L W+ P DG + + +Y ++ RE W + S +
Sbjct: 22145 GPPGP--ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI- 22201
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT-TLQAAPDEAPTILSVTPHTTTSV 1518
F V+ L Y FRV A N+ G E E E + T Q AP P L V + +S
Sbjct: 22202 -FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP---PRRLDVVDTSKSSA 22257
Query: 1519 LIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
++ W P D +I G LL R + + E G T +LT
Sbjct: 22258 VLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHT-----------KQLT------- 22297
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------PTA---- 1625
+ ++ L + YE R+ N G S P+E F + PTA
Sbjct: 22298 --------FTVERLVEKTEYEFRVKAKNDAGY---SEPREAFSSVIIKEPQIEPTADLTG 22346
Query: 1626 -APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE-RVKTLFLAEN 1683
+ + + +DV P ++ ++ E R ++T + +T ++
Sbjct: 22347 ITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK--ETDRVSITTTKDRTTLTVKD 22404
Query: 1684 SVK---------LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSE 1734
S++ L+N G + V+V G P G + ++ SA S V
Sbjct: 22405 SMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG------PVTGPIEVSSVSAESCV---- 22454
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+SW P+ G E + E ++V VK +KV L +
Sbjct: 22455 -------LSWGEPKDGGGT-EITNYIVEKRESGTTAWQLVNSSVKRTQ---IKVTHLTKY 22503
Query: 1795 VTYRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPG 1850
+ Y FR+ ++ F +E A + P P P + S+ A++I W G
Sbjct: 22504 MEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDG 22563
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
I Y +E + + LW +K+ + + L G+ Y FR A+N G
Sbjct: 22564 GSKIIGYWVEKKERNTILW---VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 22620
Query: 1911 PSSPSQSVPAQ 1921
S S+ + AQ
Sbjct: 22621 ASEASRPIMAQ 22631
Score = 161 bits (408), Expect = 6e-39
Identities = 283/1169 (24%), Positives = 437/1169 (37%), Gaps = 141/1169 (12%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLI-SPTHISDA 470
T+ G S+ L SG P P ITW K LAS ++ ES SLLI + DA
Sbjct: 23152 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI----IDTTESYSLLIVDKVNRYDA 23207
Query: 471 GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV----- 525
G YT A N G A+ + V+ T P +K V P +
Sbjct: 23208 GKYTIEAENQSGKKSATVLVKVYD----TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAP 23263
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVI-----SAGGNDSR 580
YI EK A + + + IS G + Y RV+ G
Sbjct: 23264 VNNYIVEKREAAMRAFKTVTTKCSKT-LYRISGLVEGTM--YYFRVLPENIYGIGEPCET 23320
Query: 581 SAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP-FDGNSPLIRYILEMSENNAPWT 637
S + V ++P P A L V+ + + L W KP +DG S L Y+LE +
Sbjct: 23321 SDAVLVSEVPLVP----AKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW 23376
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS------LPEEPPT 691
+ + ++ P TV L Y FR+ A N+ G + + V+ LP +
Sbjct: 23377 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23436
Query: 692 APPQNVI--ASGRTNQSIM-IQWQPPPESHQNGILKGYIIRYCLAG--LPVGYQFKNITD 746
PQ I +GR + ++ I +PPP + + AG L + T
Sbjct: 23437 TMPQKTIHVPAGRPVELVIPIAGRPPPAAS-----------WFFAGSKLRESERVTVETH 23485
Query: 747 ADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
V L + + I E + N G + KV G PT P + + ++T
Sbjct: 23486 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP---IKIDEIDAT 23542
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEE-------VTMVTARPNFQDSIHVGFVS 859
+I +W P ++ G L + EQ + V+ R F+ +
Sbjct: 23543 SITISWEPPE------LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFK-------FT 23589
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLV--RTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G G +++ R+ +PGP L ++ + ++W
Sbjct: 23590 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23649
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +TGY + +E + +P YR TGLT Y V A+ ++G
Sbjct: 23650 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23709
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVG 1033
G+ S + I + P PG P N +++ SV+L + P +G + ++ +L+E Q
Sbjct: 23710 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23769
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQT 1091
+ EW + + R + L Y FR+ N G P++ + K+
Sbjct: 23770 ---DQHEWTKCNTTPTK--IREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 23824
Query: 1092 LQAPPDMA-----PANVSLRTASETSLWL--RWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
+ PD + +R L + + P P ++ + + + + S+ H
Sbjct: 23825 MLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH 23884
Query: 1145 GKTLSHVVQDRVERDYTIEDL--EEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSS- 1201
+ V+++ D DL E + IGS P+S
Sbjct: 23885 TEL---VIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS---------------PNSP 23926
Query: 1202 -GPTNVSALATTSSSMLVRWSEVPEADRNGL-VLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
GP + S VR S P AD G +LGY + +E W + R
Sbjct: 23927 EGPLEYDDIQVRS----VRVSWRPPADDGGADILGYILERREVPKAA----WYTIDSRVR 23978
Query: 1260 SAQLT--GLGKYVLYEVQVLAFTRIGDGSP--SHPPILERTLDDVPGPPMGILFPEV--- 1312
L GL + V Y +V A + G P S P+ +T + P PP PEV
Sbjct: 23979 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP--PEVLDV 24036
Query: 1313 RTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+SV L W P G + R T+T + YT TGL P++ Y
Sbjct: 24037 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 24096
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGL 1429
FRI AQ G E + A VV + D+P P ++ + SV L WE P DG
Sbjct: 24097 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE--LEILSISKDSVTLQWEKPECDGG 24154
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+ Y ++ R+ W S F + L T Y+FRV A N+ G S
Sbjct: 24155 KEILGYWVEYRQSGDSAWK-KSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24213
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSV 1518
+ S+ T + EAP I TT +
Sbjct: 24214 TAMSIKT-KLTSGEAPGIRKEMKDVTTKL 24241
Score = 158 bits (400), Expect = 5e-38
Identities = 355/1546 (22%), Positives = 567/1546 (36%), Gaps = 189/1546 (12%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
G P P+I WYKD ++ L D + I ++G ++ RNA G +
Sbjct: 20593 GKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT 20652
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVL----ACETSGAPRPAITWQKGERILASGSVQ 448
+ + P GP++ + + L + GA +K E S+
Sbjct: 20653 IRVQILD-KPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMV 20711
Query: 449 LPRFTPLESGSLLISPTHISDAGTY--TCLATNSRGVDE-ASADLVVWARTRITK-PPQD 504
+I+ T I Y A N G+ E +D VV +T PP
Sbjct: 20712 SEHLE-----ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 20766
Query: 505 QSVIKGTQASMVCGVTH-----DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
V K T+ SM + ++ ++ ++D +LG + + T
Sbjct: 20767 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLT 20826
Query: 560 WSGDIGTYTCRVISAG-GNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
+ D C V +AG G S + P P P A + + + +I L W+KP
Sbjct: 20827 ENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPV 20886
Query: 616 FDGNSPLIRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S + Y++E+ + WT + + + T V L P +Y FR+ AVN G+G
Sbjct: 20887 YDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG 20946
Query: 675 QFSKDTERVSLPE--EPP-----TAPPQNVIASGRTNQSIMIQW--QPPPESHQNGILKG 725
+ + E V + E P A +VIA + ++I + +PPP K
Sbjct: 20947 EPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKN 21006
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
G Y +N D ++LL + + + + G+G S
Sbjct: 21007 -------LGSDARYSIEN---TDSSSLLTIPQVTRNDTGKYILTIEN-GVGEPKSSTVSV 21055
Query: 786 TLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTA 845
+ P + + + T+ W+ P I+ G +I + E+ + +
Sbjct: 21056 KVLDTPAACQ-KLQVKHVSRGTVTLLWDPPL------IDGGSPIINYVIEKRDATKRTWS 21108
Query: 846 RPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFS 904
+ + S + L + T +F VL G G P T + V+ E VP P+ LS
Sbjct: 21109 VVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE-VPAPIRDLSMK 21167
Query: 905 EILDTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTT 963
+ TS+ +SW +P G ++T Y + E + +H + T E V+ L +
Sbjct: 21168 DSTKTSVILSWTKPDFDGGSVITEYVV--ERKGKGEQTWSHAGISKTCEIEVSQLKEQSV 21225
Query: 964 YTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPG------Y 1017
V A KG TI EL P + +S+I VT++ Y
Sbjct: 21226 LEFRVFAKNEKGLS--DPVTIGPITVKELIITP-EVDLSDIPGAQVTVRIGHNVHLELPY 21282
Query: 1018 DGKTSIS-RW------LVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
GK S W L E++ + E + + + + + L+ C
Sbjct: 21283 KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRI-- 21340
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPE 1130
+ ++ PPS+P I+ + D S+ L W +P E NG E
Sbjct: 21341 AVPITVITLGPPSKPKGPIRFDEIKAD--------------SVILSW-DVP--EDNGGGE 21383
Query: 1131 SVGYKI-KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-S 1187
Y I K S + K + V + + +L + EY+ +V+A N G S P S
Sbjct: 21384 ITCYSIEKRETSQTNWKMVCSSV---ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21440
Query: 1188 QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS--- 1244
+V + + +P P TS M + W + P D V G+ V KE++S
Sbjct: 21441 SIIVAKHQFRIPGP-PGKPVIYNVTSDGMSLTW-DAPVYDGGSEVTGFHVEKKERNSILW 21498
Query: 1245 ---DTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD--D 1299
+T P S R + TGL + + Y+ +V A G SPS P + D
Sbjct: 21499 QKVNTSP-------ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVD 21551
Query: 1300 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSA 1357
PG P I +V ++ L W PP G I+ Y I R N +V S
Sbjct: 21552 PPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDV---SE 21605
Query: 1358 RQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARS 1417
QYT TGL P Y FRI A+ G RD P P+V+
Sbjct: 21606 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVP---PIVEFGPEYFDG 21662
Query: 1418 VLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY----- 1472
+++ G S +Q R +P W + + I D L + +
Sbjct: 21663 LII-----KSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT 21717
Query: 1473 -----KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAE 1527
+ V+A N G S ++E +Q P + + T T + + W P
Sbjct: 21718 RDHRGVYTVEAKNASG----SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLN 21773
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
D I + I RE WA + S T +L
Sbjct: 21774 DGCAPI-THYIIEKRE---------------TSRLAWALIED-----KCEAQSYTAIKLI 21812
Query: 1588 NLNKHRRYEIRMSVYNAVGEGP--SSPPQEVFVGEAVPTA----APRNVVVHGATATQLD 1641
N N+ Y+ R+S N G G S P + VP A P N+ T +
Sbjct: 21813 NGNE---YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNI-----TGNSIT 21864
Query: 1642 VTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVA 1701
+TW P D +IQ Y + E + + + ++E K+ LT Y V
Sbjct: 21865 LTWARPESDG-GSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVM 21923
Query: 1702 AFNAAGDGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGY 1757
A NAAG GP S + + + P P+ VK ++ + T+V++ W P F G+ + GY
Sbjct: 21924 AENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGY 21983
Query: 1758 RLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA 1803
+ E C + V+ + V DL G Y+FR+ A
Sbjct: 21984 --IIEMCKA--DLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSA 22025
Score = 158 bits (399), Expect = 6e-38
Identities = 319/1434 (22%), Positives = 534/1434 (37%), Gaps = 160/1434 (11%)
Query: 531 WEKDGATLGTESHPRIRLD-RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W KD A + + I+ +L + D G Y V ++ G+ + V
Sbjct: 10547 WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10606
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P PV+ V + + ++W P D G S + YI+E E + + S K T
Sbjct: 10607 PGPPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-T 10664
Query: 649 SVTVKGLVPARSYQFRLCAVNDVG-KGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
+ V L+ + Y FR+ A N G D+ + P AP Q ++ T S
Sbjct: 10665 TCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEV-TKDSA 10723
Query: 708 MIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNITDADVN---NLLLEDLIIWTNY 763
++ W P H G + YI+ + ++ +T ++ + DL+ Y
Sbjct: 10724 LVTWNKP---HDGGKPITNYILE---KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 10777
Query: 764 EIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
E V+A N G+G S SK PP N A T ++ TW P +
Sbjct: 10778 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10837
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG- 880
I GY ++ ++ +EE P V+GL+ Y VL G+
Sbjct: 10838 KI-LGY-IVEYQKVGDEEWRRANHTPESCPETKYK-VTGLRDGQTYKFRVLAVNAAGESD 10894
Query: 881 PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGY---RISWEEYNR 937
P P+ V + + P L + + +KV + + I+ G +++W++ +R
Sbjct: 10895 PAHVPEPVLVKDRLEPPELILDANMAREQHIKVG--DTLRLSAIIKGVPFPKVTWKKEDR 10952
Query: 938 ---TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGV-PPELP 993
T R+ LE R Y++ V + + T+S V + P
Sbjct: 10953 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLVLDKP 11005
Query: 994 GPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
GPP +L +S I S L ++ P DG + I+ ++VE + +W LS
Sbjct: 11006 GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVA---SAQW---SPLSATSK 11059
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ-APPDMAPANVSLRTASET 1111
+S LN Y FR+ N G P + + I+ L P P ++ +T
Sbjct: 11060 KKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKT 11119
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG----KTLSHVVQDRVERDYTIEDLEE 1167
+ L W + + +G GY ++Y KT++++ + + L++
Sbjct: 11120 EVSLVW---NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNL-------ECVVTGLQQ 11169
Query: 1168 WTEYRVQVQAFNAIGSGPWSQTVVGRTRES-VPSSGPTNVSAL--------ATTSSSMLV 1218
YR +V+A N +G G T+ +E VP S +V + T ++
Sbjct: 11170 GKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAII 11229
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
R VP A K + T + + N S + + E Q+
Sbjct: 11230 RGVPVPTA---------KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI-- 11278
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQIT 1337
+ + + S + T+ DVPGPP G I +V + + WQPP G + I
Sbjct: 11279 --TVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIV 11336
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEK 1396
+ T +T V S + L+ Y+FR+ A+ + G G ++ V K
Sbjct: 11337 EK-QDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHK 11395
Query: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
P PP +P+V D+ + +SW P SDG SP+ Y ++ RE+ +G+W + +
Sbjct: 11396 FSPPSPPGKPVV--TDITENAATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPI 11452
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHT 1514
+ F V L +Y+FRV A N G S+ S S+ + + P I + +
Sbjct: 11453 ADL-KFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS 11511
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMR 1574
+ + W P D + IL G+ + A W + +R
Sbjct: 11512 RETADLVWTKPLSDGGSPIL----------------GYVVECQKPGTAQWNRINKDELIR 11555
Query: 1575 NLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVVV 1632
+ + + L + Y R+ N VGEG E + + + P +V
Sbjct: 11556 QCA------FRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTC 11609
Query: 1633 HGATATQLDVTW----------EPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
++ T EP ++ G + R + ++ L E
Sbjct: 11610 RDVITVRVGQTIRILARVKGRPEPDITWTKEGKV---------LVREKRVDLIQDLPRVE 11660
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
+K + Y++S A N++G S + P ++K + +T + +
Sbjct: 11661 LQIKEAVRADHGKYIIS--AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKENCTI 11715
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIR 1802
SWE P NG E + E P IV DV + +K LA Y FR+
Sbjct: 11716 SWENP-LDNGGSEITNFIVEYRKPNQKGWSIVASDV---TKRLIKANLLANN-EYYFRVC 11770
Query: 1803 AKT-FTYGPEIEA-------NVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD-PGKGP 1853
A+ GP IE N PGE P + I + + + + W D G P
Sbjct: 11771 AENKVGVGPTIETKTPILAINPIDRPGE----PENLHIADKGKTFVYLKWRRPDYDGGSP 11826
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG 1907
Y +E R W+ + K KE + +D Y+FRV N+ G
Sbjct: 11827 NLSYHVERRLKGSDDWERVHKGSIKETH---YMVDRCVENQIYEFRVQTKNEGG 11877
Score = 158 bits (399), Expect = 6e-38
Identities = 293/1278 (22%), Positives = 490/1278 (38%), Gaps = 155/1278 (12%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW-YKDAAVVEVEKLTRFRQR 360
L VL P++ I + V++ G PPP+ +W + + + E E++T
Sbjct: 23427 LRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 23486
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
L I DTG + +N G + T + P GP+ ID S+
Sbjct: 23487 KVAKLTIRETTIRDTGEYTLELKNVTG-TTSETIKVIILDKPGPPTGPIKIDEIDATSIT 23545
Query: 421 LACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISP---THISDAGTY 473
++ E GAP ++ P + P+ S S+ S T +++ Y
Sbjct: 23546 ISWEPPELDGGAPLSGY-------VVEQRDAHRPGWLPV-SESVTRSTFKFTRLTEGNEY 23597
Query: 474 T--CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
ATN G+ V+ R+ I P +++ + V+ D Y
Sbjct: 23598 VFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETL-------QIFDVSRDGMTLTWYPP 23650
Query: 532 EKDGATLGT---ESHPRIRLD---RNGSLHISQTWSGDIG-----TYTCRVIS----AGG 576
E DG + T +R D R + ++ T G Y RV + G
Sbjct: 23651 EDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 23710
Query: 577 NDSRSAHLRVRQLPHA----PEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSE 631
SR + V P A P++P T +T R +++L W+ P D G S + Y++EM +
Sbjct: 23711 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTT--RTSVSLAWSVPEDEGGSKVTGYLIEMQK 23768
Query: 632 NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS------KDTERVSL 685
+ + K T+ L Y+FR+ A N G G+ + K TE +
Sbjct: 23769 VDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEY 23828
Query: 686 PEEPPTAPPQN---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
P+ Q V G +I I+ +P P I ++ G + +
Sbjct: 23829 PDYELDERYQEGIFVRQGGVIRLTIPIKGKPFP-----------ICKWTKEGQDISKRAM 23877
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEA 802
T L++++ + ++ N G KV + G P P G + +
Sbjct: 23878 IATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKV---RVIGSPNSPEGPLEYDD 23934
Query: 803 TNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSG 860
++R +W P+ + G ++ + E+ E + T + + V V G
Sbjct: 23935 IQVRSVRVSWRPPAD------DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKG 23986
Query: 861 LKKFTEYFTSVLCFTTPG-DGPRSTPQLVRTHEDVPGPVGHLSFSEILD---TSLKVSWQ 916
LK+ EY V G P + + V + P + E+LD +S+ +SW
Sbjct: 23987 LKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 24046
Query: 917 EPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSK 974
P + G +TGY I +E T+ V H +T Y VTGL Y + A
Sbjct: 24047 RPKDDGGSRVTGYYIERKE-TSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDV 24105
Query: 975 GQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYD-GKTSISRWLVEA 1030
G + S ++ + P + P P L I +I SVTLQ+ +P D GK + W+
Sbjct: 24106 GLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYR 24165
Query: 1031 QVGVVGEGEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
Q G W + SN+ + + + L T Y FR+ N G S P + +
Sbjct: 24166 QSG----DSAW----KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 24217
Query: 1089 IQTL----QAP---PDMAPANVSLRTASETSLWLRWMPLPEME-YNGNPESVGYKIKYSR 1140
I+T +AP +M L A++ S + PLP+++ Y E + +
Sbjct: 24218 IKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 24277
Query: 1141 SDGHGKTLSHVVQDRVERDY-----TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRT 1194
SDG TL+ + +++ + T E E T ++ +QA G P + G
Sbjct: 24278 SDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG-- 24335
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKD---SDTQPRFW 1251
+V S+ +V + +M W G K++ ++ +T+
Sbjct: 24336 --AVGSTLRLHVMYIGRPVPAM--TWFH-----------GQKLLQNSENITIENTEHYTH 24380
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFP 1310
LV N R T GKY + V + IL+ + D P P G I+
Sbjct: 24381 LVMKNVQRK---THAGKYKVQLSNVFG---------TVDAILDVEIQDKPDKPTGPIVIE 24428
Query: 1311 EVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
+ S + W+PPA G + + + + A S L +
Sbjct: 24429 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 24488
Query: 1371 YLFRITAQTRKGWGEAAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSD 1427
Y FR++AQ G + E ++V+ ++P P +P + V S +++W+ P SD
Sbjct: 24489 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA--VTKDSCVVAWKPPASD 24546
Query: 1428 GLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEF 1487
G + +R Y ++ RE +W + + + F V L Y+FRVK N G+SE+
Sbjct: 24547 GGAKIRNYYLEKREKKQNKW-ISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24605
Query: 1488 SEESESLTTLQAAPDEAP 1505
SE SE +T P +AP
Sbjct: 24606 SEISEPITPKSDVPIQAP 24623
Score = 154 bits (390), Expect = 7e-37
Identities = 325/1603 (20%), Positives = 591/1603 (36%), Gaps = 176/1603 (10%)
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV-EVEKLTRFRQRNDGGLQISGLVPDDT 375
++ A + +D+P KG P ++ W KD + E ++ + L I +D
Sbjct: 19100 NVKAREQLKIDVPF--KGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDV 19157
Query: 376 GMFQCFARNAAGEVQTS-TYLAVTSIAPNITRGPLDSTVIDGMSVVLA---------CET 425
G ++ N+AG + T + + P GP+ + S+ ++ C+
Sbjct: 19158 GTYELCVSNSAGSITVPITIIVLDRPGPP---GPIRIDEVSCDSITISWNPPEYDGGCQI 19214
Query: 426 SG-----APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
S + TW + +A S+++ R T +GS + A N
Sbjct: 19215 SNYIVEKKETTSTTWHIVSQAVARTSIKIVRLT---TGSEY----------QFRVCAENR 19261
Query: 481 RGVDEASADLVVWARTRITKP--PQDQSVIKGTQASM--------------VCGVTHDPR 524
G S V A + P P V+ T+++M V G + +
Sbjct: 19262 YGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYK 19321
Query: 525 VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH- 583
+W K L ++ ++ G ++ + ++ +I G S+S
Sbjct: 19322 ERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGI--------GKCSKSCEP 19373
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+ R P P T + R++++L W+KP +DG + + YI+E E +
Sbjct: 19374 VPARDPCDPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 19431
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGK-GQFSKDTERVSLPEEPPTAPPQNVIASG 701
+ + T V L + Y+FR+ A N + S+ T + + ++ P V+
Sbjct: 19432 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDD---VEPPRVMMDV 19488
Query: 702 RTNQSIMIQWQPPPESHQNGILKGY---IIRYCLAGLPVGYQFKN-ITDADVNNLL-LED 756
+ I+++ + N + G +I + G+ + + + I D + LL ++D
Sbjct: 19489 KFRDVIVVKAGEVLKI--NADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 19546
Query: 757 LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
I + + N AG S + P P G + + +W P
Sbjct: 19547 CIRRDTGQYVLTLKNVAGT---RSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 19603
Query: 817 PQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTT 876
G + Y ++ E + + Q + V+ L K EY V
Sbjct: 19604 ED--GGADIDYYIV--EKRETSHLAWTICEGELQMTSCK--VTKLLKGNEYIFRVTGVNK 19657
Query: 877 PGDGPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G G ++ + VP P L + + S+ + W P G ++GY I
Sbjct: 19658 YGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERR 19717
Query: 934 EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST--ISSGVPPE 991
E N + P L + TGL Y V A + G S ++ I + P
Sbjct: 19718 EKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVF 19777
Query: 992 LPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 1050
LP PP+ I + G ++T+ + +P +DG I+ + VE + + +W Q
Sbjct: 19778 LPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKS---DDTDWKTSIQSLRG 19834
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS-------RKIQTL-QAPPDMAPAN 1102
+ + L Y FR++ VN VG S PS S R+ + L +M
Sbjct: 19835 TE---YTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTL 19891
Query: 1103 VSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTI 1162
+ AS T M +P + G P + +S+ D +T ++V TI
Sbjct: 19892 IVKAGASFT------MTVP---FRGRPVP---NVLWSKPDTDLRTRAYVDTTDSRTSLTI 19939
Query: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222
E+ + + N + + S T+V + ++ PTN++ T S ++ W +
Sbjct: 19940 ENANRNDSGKYTLTIQNVLSAA--SLTLVVKVLDT--PGPPTNITVQDVTKESAVLSW-D 19994
Query: 1223 VPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR-SAQLTGLGKYVLYEVQVLAFTR 1281
VPE D V Y + EK ++ + V N +R S ++T L + +Y +V
Sbjct: 19995 VPENDGGAPVKNYHI---EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENE 20051
Query: 1282 IGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLN 1341
G G P+ + + + P PP + + SV L W P G + + + L
Sbjct: 20052 FGVGIPAETKEGVK-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALE 20110
Query: 1342 TTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQ 1401
N V+ + + +GL+ S Y FR+ A+ + G + E L+ K ++ +
Sbjct: 20111 KGQKNW--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIK-EQLE 20167
Query: 1402 PPSRPMVQQED----VRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
PP M VRA S L P S P+ T+ +P + ++
Sbjct: 20168 PPEIDMKNFPSHTVYVRAGSNLKVDIPISG--KPLPKVTLSRDGVPLKATMRFNTEITAE 20225
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
+ + + ++ + A N G ++ L + P P ++S T S
Sbjct: 20226 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLD--RPGPPTGPVVISDI--TEES 20281
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLS 1577
V ++W+PP D + + + L A W E+++ + +
Sbjct: 20282 VTLKWEPPKYDGGSQVT----------------NYILLKRETSTAVWTEVSATVARTMMK 20325
Query: 1578 RPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVV-VHGAT 1636
LT E Y+ R+ N G V V T P + V T
Sbjct: 20326 VMKLTTGE--------EYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVT 20377
Query: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAY 1696
+ V W P + + + GY + + + L ++ L + K+ ++ Y
Sbjct: 20378 RESITVGWHEP-VSNGGSAVVGYHLEMKD-RNSILWQKANKLVIRTTHFKVTTISAGLIY 20435
Query: 1697 MVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LE 1755
V A NAAG G S P++ A P +V+ ++++ SV++SW+ P F G +
Sbjct: 20436 EFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKIT 20495
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPE 1811
GY + E DG + + + L + Y FR+ A+ + + E
Sbjct: 20496 GY--IVERRDLPDG--RWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20551
Query: 1812 IEANVTTGPGEGAPG---PPGVPIIVRYSSAIAIHWSSGDPGK 1851
+ +T G P P +V+Y + ++ +G GK
Sbjct: 20552 VVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 20594
Score = 149 bits (376), Expect = 3e-35
Identities = 359/1701 (21%), Positives = 599/1701 (35%), Gaps = 236/1701 (13%)
Query: 305 LEPPQFVKEPERH--ITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTR---FRQ 359
+EPP+ + + + I + +V+ I G P P I+W KD +E+E+ R
Sbjct: 19479 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDG--IEIEERARTEIIST 19536
Query: 360 RNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSV 419
N L + + DTG + +N AG + V P GPL+ +
Sbjct: 19537 DNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLD-KPGPPAGPLEINGLTAEKC 19595
Query: 420 VLAC----ETSGAPRPAITWQKGER-----ILASGSVQLP--RFTPLESGSLLISPTHIS 468
L+ E GA +K E + G +Q+ + T L G+ I
Sbjct: 19596 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI------ 19649
Query: 469 DAGTYTCLATNSRGVDEASADLVVWARTRIT--KPPQDQSVIKGTQASMVCGVTHDPRVT 526
+ N GV E + + A T PP + T+ SM
Sbjct: 19650 ----FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMT---------- 19695
Query: 527 IRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W + + G+E I ++R + Y RV S G + RV
Sbjct: 19696 --LCWSRPESDGGSEISGYI-IERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRV 19752
Query: 587 RQ-----------------------LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPL 622
LP P P S + I + W KP FDG +P+
Sbjct: 19753 YAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDS--GKTTITIAWVKPLFDGGAPI 19810
Query: 623 IRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTE 681
Y +E + ++ W + S+ + T T+ GL Y FR+ +VN VG S ++
Sbjct: 19811 TGYTVEYKKSDDTDWKTSIQSL--RGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19868
Query: 682 RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILK---GYIIRYCLAGLPVG 738
PQ IA R + + + E + I+K + + G PV
Sbjct: 19869 ------------PQ--IAKEREEEPL---FDIDSEMRKTLIVKAGASFTMTVPFRGRPVP 19911
Query: 739 YQFKNITDADVNNLLLEDLI-IWTNYEIEVAAYNSAG------LGVYSSKVTEWTLQGVP 791
+ D D+ D T+ IE A N +G V S+ ++ +
Sbjct: 19912 NVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLD 19971
Query: 792 TV-PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 850
T PP N+ + + +W+ P N K E + + V+ N
Sbjct: 19972 TPGPPTNITVQDVTKESAVLSWDVPE----NDGGAPVKNYHIEKREASKKAWVSVTNNCN 20027
Query: 851 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDT 909
+ V+ L++ Y+ V G G P T + V+ E P P L + I
Sbjct: 20028 RLSYK--VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK-PSPPEKLGVTSISKD 20084
Query: 910 SLKVSWQEPGEKNGI-LTGYRISWEEYNRTN------TRVTHYLPNVTLEYRVTGLTALT 962
S+ ++W +P G + Y + E + N + TH++ V+GL +
Sbjct: 20085 SVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHV--------VSGLRENS 20136
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
Y V A G + + +L P + + N S T+ R G + K
Sbjct: 20137 EYFFRVFAENQAGLSDPRELLLPVLIKEQL--EPPEIDMKNF--PSHTVYVRAGSNLKVD 20192
Query: 1023 IS-RWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +V + +G + + E A ++ + T + R ++ +S
Sbjct: 20193 IPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY-EITAANSSG 20251
Query: 1082 PSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY-KIKYS 1139
++ I L P P P +S +E S+ L+W P +Y+G + Y +K
Sbjct: 20252 TTKAFINIVVLDRPGPPTGPVVIS--DITEESVTLKWEP---PKYDGGSQVTNYILLKRE 20306
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
S +S V + + + L EY+ +++A N G + +
Sbjct: 20307 TSTAVWTEVSATVARTMMK---VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYT 20363
Query: 1200 SSGPTNVSALA-TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN-- 1256
+ GP + + T S+ V W E P ++ V+GY + K+++S W
Sbjct: 20364 TPGPPSTPWVTNVTRESITVGWHE-PVSNGGSAVVGYHLEMKDRNS----ILWQKANKLV 20418
Query: 1257 -SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVR 1313
+ ++T + ++YE +V A G G PSHP P+L D PP + ++
Sbjct: 20419 IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVL---AIDACEPPRNVRITDIS 20475
Query: 1314 TTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
SV L WQ PA G + I R + + Q+ +GL S Y F
Sbjct: 20476 KNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEF 20535
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPP--SRPMVQQEDVRARS-VLLSWEPGSDGL- 1429
R+ A+ G +V D P P+ E V+ R+ + G G
Sbjct: 20536 RVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKP 20595
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+P + +EL + AL + + +S ++ S + +K N +G + +
Sbjct: 20596 APTIEWYKDDKELQTN--ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 20653
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGL 1549
+ L + P P + T + + W+PPA+D G +I +
Sbjct: 20654 RVQILD--KPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITH-------- 20695
Query: 1550 RGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP 1609
+ + W+ ++ +L +T + K Y R+ N G G
Sbjct: 20696 --YIVEKRETSRVVWSMVS-----EHLEECIIT---TTKIIKGNEYIFRVRAVNKYGIGE 20745
Query: 1610 SSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR 1668
V A T P + V T + V W P D DI G YF E +
Sbjct: 20746 PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADG-GSDISG---YFLEKRD 20801
Query: 1669 GNLTERVKTL--FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ---GQTQQAA 1723
K L + + K+ LT + Y V A NAAG GP S P++
Sbjct: 20802 KKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 20861
Query: 1724 PSAPSSVKFSELTTTSVNVSWEAPQFPNG-ILEGYRLVYEPCSPVDGVSKIVTVDVKGN- 1781
P P+ ++ ++ T +S+ + W P + G + GY + + TV KG
Sbjct: 20862 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE----EEWTTVSTKGEV 20917
Query: 1782 SPLWLKVKDLAEGVTYRFR------------------IRAKTFTYGPEIEANVTTGPGEG 1823
V +L GV Y FR ++AK PEI+ +V
Sbjct: 20918 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVI 20977
Query: 1824 APGPPGVPIIVRYSS--AIAIHWSSGDPGKGPITRYVIEARPS------------DEGLW 1869
A V +++ + + W + G RY IE S D G +
Sbjct: 20978 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 21037
Query: 1870 DILIKDIPKEVSSYTFSMDIL 1890
+ I++ E S T S+ +L
Sbjct: 21038 ILTIENGVGEPKSSTVSVKVL 21058
Score = 149 bits (376), Expect = 3e-35
Identities = 360/1644 (21%), Positives = 594/1644 (36%), Gaps = 223/1644 (13%)
Query: 367 ISGLVPDDTGMFQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMS 418
++ L + +F+ A+N G E T+ + + P I + I G
Sbjct: 23391 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23450
Query: 419 VVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
V L +G P PA +W G ++ S V + T + L I T I D G YT
Sbjct: 23451 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV--AKLTIRETTIRDTGEYTLEL 23508
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASM------------VCGVTHDPRV 525
N G + +++ + P I T ++ + G + R
Sbjct: 23509 KNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRD 23568
Query: 526 TIRYIW--EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
R W + T T R+ ++ T IG+Y + + + RS+
Sbjct: 23569 AHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSI 23624
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
++P PE + V R + LTW P D G S + YI+E E A V +
Sbjct: 23625 ----RIPGPPE--TLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNK 23678
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER-VSLPEEPPTAPPQNVIASG 701
V T GL Y+ R+ A+N G G+ S+ ++ V++ P PQN +
Sbjct: 23679 VPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTD 23738
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T S+ + W P E + GY+I + N T + L L
Sbjct: 23739 TTRTSVSLAWSVP-EDEGGSKVTGYLIEMQKVDQHEWTKC-NTTPTKIREYTLTHLPQGA 23796
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
Y V A N+ G G P PG V + + + ++
Sbjct: 23797 EYRFRVLACNAGG-------------PGEPAEVPGTVKV----TEMLEYPDYELDERYQE 23839
Query: 822 GI--NQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
GI QG + P + + + QD ++ + TE V+ GD
Sbjct: 23840 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL---VIKEADRGD 23896
Query: 880 ------------GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
G ++ VR P G L + +I S++VSW+ P + G +
Sbjct: 23897 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23956
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV--SASTI 984
GY + E + T V GL Y V+A G + S +
Sbjct: 23957 GYILERREVPKAAWYTIDSRVRGT-SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 24015
Query: 985 SSGVPPELPGPPTNLG-ISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWL 1042
+ P P PP+N + ++ SV+L + RP DG + ++ + +E + ++W
Sbjct: 24016 TPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETST---DKW- 24071
Query: 1043 LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG---TSPPSQPSRKIQTLQAPPDMA 1099
+ + V L P Y FR+ N VG TSP S+P P
Sbjct: 24072 -VRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQ-- 24128
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ER 1158
P + + + S+ S+ L+W + E +G E +GY ++Y +S S+ ++R+ ++
Sbjct: 24129 PGELEILSISKDSVTLQW---EKPECDGGKEILGYWVEYRQSGDSAWKKSN--KERIKDK 24183
Query: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP----------TNVSA 1208
+TI L E TEY +V A N G +T + + P T +
Sbjct: 24184 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGE 24243
Query: 1209 LATTSSSMLVRWSEVPEADRNGLVLGYKVMYK-EKDSDTQPRFWLVEGNSSRSAQLTGLG 1267
A S ++ R + R G L YK D T + E G
Sbjct: 24244 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDE-------G 24296
Query: 1268 KYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL----IWQP 1323
Y +A +G+ S +L+ T PG P+ + +++RL I +P
Sbjct: 24297 VYTC-----IATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRP 24351
Query: 1324 PAAPNGIILAYQITHRLNTTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A + + N T NT ++ + ++ T G +++ G
Sbjct: 24352 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK-------YKVQLSNVFG 24404
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYTIQTRE 1441
+A ++ E +D+P P+ P+V E + S ++SW+P DG S + Y ++ E
Sbjct: 24405 TVDA----ILDVEIQDKPDKPTGPIVI-EALLKNSAVISWKPPADDGGSWITNYVVEKCE 24459
Query: 1442 LPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
G W L S+++S + L Y FRV A N G S+ E S + +
Sbjct: 24460 AKEGAEWQLVSSAISVTTCRIV--NLTENAGYYFRVSAQNTFGISDPLEVSS--VVIIKS 24515
Query: 1501 PDE---APTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
P E AP ++T T S ++ W+PPA D G +IR + L
Sbjct: 24516 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDG------GAKIR----------NYYLEKR 24559
Query: 1558 NNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617
W +T+ T + + NL + YE R+ N GE S E
Sbjct: 24560 EKKQNKWISVTTEEIRE-------TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPI 24612
Query: 1618 VGEA-VPTAAPR--------NVVVHGATATQLDVTWEPPPL------------DSQNGDI 1656
++ VP AP NV VT P P+ D I
Sbjct: 24613 TPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRI 24672
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ 1716
Q +K + + ++T+ T++ + + +++G + V V A P++
Sbjct: 24673 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL---PKTLEGM 24729
Query: 1717 GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTV 1776
G A S+K ++W+ Q Y+++ V++ T
Sbjct: 24730 GAVH-ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI---------VTRSFTS 24779
Query: 1777 DVKGNSPLWLKVKDLAEGVTY---RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPII 1833
V N ++ KD V RF I KT +E +V P P GV +
Sbjct: 24780 LVFPNG---VERKDAGFYVVCAKNRFGIDQKT------VELDVADVPDP----PRGVKVS 24826
Query: 1834 VRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892
++ + W+ G IT Y++E + W + + +++ L
Sbjct: 24827 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-----GQARETRYTVINLFG 24881
Query: 1893 GVSYDFRVIAVNDYGFGTPSSPSQ 1916
SY FRVIA N +G PS PS+
Sbjct: 24882 KTSYQFRVIAENKFGLSKPSEPSE 24905
Score = 147 bits (372), Expect = 8e-35
Identities = 327/1497 (21%), Positives = 538/1497 (35%), Gaps = 177/1497 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
ND G+ ++PD + R A + + L T + V G+S+
Sbjct: 14447 NDAGVGEPAVIPD----VEIVEREMAPDFELDAELRRTLV------------VRAGLSIR 14490
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT-HISDAGTYTCLATN 479
+ G P P +TW K L + + ES +LLI P + D G + N
Sbjct: 14491 IFVPIKGRPAPEVTWTKDNINLKNRA----NIENTESFTLLIIPECNRYDTGKFVMTIEN 14546
Query: 480 SRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH--------DPRVTIRYIW 531
G + R+ P ++ T + H R+T YI
Sbjct: 14547 PAGKKSG------FVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT-NYIV 14599
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA-----GGNDSRSAHLRV 586
EK AT + S + + T + Y RV++ G + ++
Sbjct: 14600 EKREATRKSYSTATTKCHK---CTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14656
Query: 587 RQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDP 645
+ P P+ + + + ++L W KP DG S + Y++E + + +V
Sbjct: 14657 SEAPSPPDS--LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV-- 14712
Query: 646 KATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT-----ERVSLPEEPPTAPPQN-VIA 699
K V+ L Y F++ AVN G+ + E+ LPE Q VIA
Sbjct: 14713 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIA 14772
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
N + I P+ I++ V ++ T A L + + +
Sbjct: 14773 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQR---VNFE----TTATSTILNINECVR 14825
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
+ + A N G V + +P P G + + +S + F+W+ P
Sbjct: 14826 SDSGPYPLTARNIVG---EVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPEND- 14881
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
G+ ++ E Q + T V + + + L EY V G
Sbjct: 14882 -GGVPISNYVV--EMRQTDSTTWVELATTVIRTTYKA--TRLTTGLEYQFRVKAQNRYGV 14936
Query: 880 GPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYN 936
GP T + + VPGP G + + S+ +SW EP G + GY + +E N
Sbjct: 14937 GPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERN 14996
Query: 937 RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA--MTSKGQGQVSASTISSGVPPELPG 994
+ ++ +GLT Y V A M K + + + + P + PG
Sbjct: 14997 GILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPG 15056
Query: 995 PPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDA 1053
P L NI +VTL++ +P Y G I+ ++VE + G + + L NE
Sbjct: 15057 KPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENE--- 15110
Query: 1054 RSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQPSRKI---QTLQAPP---DMAPANVSLR 1106
V L Y FR+ N G SPPS+PS I ++AP D+ + +
Sbjct: 15111 --FTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 15168
Query: 1107 TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIE 1163
A E + P P ME++ + + + K ++ + V +D T
Sbjct: 15169 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIK------IADFSTNLVNKDSTRR 15222
Query: 1164 DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEV 1223
D +T + A N G V R P GP V+ + TS ++ W
Sbjct: 15223 DSGAYT-----LTATNPGGFAKHIFNVKVLDRPG-PPEGPLAVTEV--TSEKCVLSW--F 15272
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL--TGLGKYVLYEVQVLAFTR 1281
P D G + + ++ K +T W + + +L T L K Y +V+A +
Sbjct: 15273 PPLDDGGAKIDHYIVQKR---ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNK 15329
Query: 1282 IGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRL 1340
G G P P+L P PP + S+ + W P + G + I R
Sbjct: 15330 YGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR 15389
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG--EAAEALVVTTEKRD 1398
+ + +Y +GL Y FRI A+ G +
Sbjct: 15390 DKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 15449
Query: 1399 RPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
+P PP P V D S+ ++W +P DG S + Y ++ W + +
Sbjct: 15450 KPGPPGNPRVL--DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLK 15507
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
A+S+ + L YK R+ A N G E P ++ TP
Sbjct: 15508 ATSYTITGLTENQEYKIRIYAMNSEGLGE------------------PALVPGTPKAEDR 15549
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT-LRGINNPGATWAELTSMYSMRNL 1576
+L P E +++ L + R LR F ++G P WA S+
Sbjct: 15550 ML-----PPEIELDADLRKV-VTIRACC--TLRLFVPIKGRPAPEVKWAR-DHGESLDKA 15600
Query: 1577 SRPSLTQYEL---DNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVV 1631
S S + Y L N+N+ + ++V N SS + FV V P+++
Sbjct: 15601 SIESTSSYTLLIVGNVNRFDSGKYILTVEN------SSGSKSAFVNVRVLDTPGPPQDLK 15654
Query: 1632 VHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA---ENSVKLK 1688
V T T + +TW+PP LD G KI + ++ T + + + S K+
Sbjct: 15655 VKEVTKTSVTLTWDPPLLDG------GSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVD 15708
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
L +Y V A N G G + + P P + ++T SV++SWE P+
Sbjct: 15709 QLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPE 15768
Query: 1749 FPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
G + GY +V D + TV V + + L +G Y FR+ A+
Sbjct: 15769 HDGGSRILGY-IVEMQTKGSDKWATCATVKVTEAT-----ITGLIQGEEYSFRVSAQ 15819
Score = 142 bits (357), Expect = 5e-33
Identities = 357/1681 (21%), Positives = 598/1681 (35%), Gaps = 218/1681 (12%)
Query: 289 RSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAV 348
RS +VP V + V+EP VK + ++ + + I G P P+ITW KD
Sbjct: 16910 RSLAVPIVAKDL---VIEPD--VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG-- 16962
Query: 349 VEVEKLTRFRQRND---GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ +++ TR + L I DD G + N G+ +T++ VT P+
Sbjct: 16963 LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-KTASIEIVTLDKPDPP 17021
Query: 406 RGPLDSTVIDGMSVVLACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+GP+ + S+ L+ T G QK + V + +L
Sbjct: 17022 KGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVV---SATVARTTLK 17078
Query: 462 ISPTHISDAGTYTCLATNSRGVDEA--SADLVVWARTRITKPP---------QDQSVIK- 509
++ + A N G A S +V + PP +D VI+
Sbjct: 17079 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 17138
Query: 510 ----GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIG 565
S V G + + +W K T+ ++ + + ++ + +
Sbjct: 17139 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQ-------NLEEGIEYEFR 17191
Query: 566 TYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIR 624
Y ++ G S R P P + V+R I L WTKP +DG S +
Sbjct: 17192 VYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITG 17249
Query: 625 YILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT---- 680
YI+E + + + + T TV GL + Y+FR+ A N G D+
Sbjct: 17250 YIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 17309
Query: 681 ---ERVSLP--EEPPTAPPQNVIASGRT-NQSIMIQWQPPPESHQNGILKGYIIRYCLAG 734
+ V LP P V+ +G T + +P P +
Sbjct: 17310 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP---------------TIEW 17354
Query: 735 LPVGYQFKNITDADVNN------LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ 788
L + + ++ N L+++D I + + A N AG + V +
Sbjct: 17355 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV---KVL 17411
Query: 789 GVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN 848
P P G V S TW SP +G + + + E V A
Sbjct: 17412 DRPGPPEGPVQVTGVTSEKCSLTW---SPPLQDGGSDISHYVVEKRETSRLAWTVVASEV 17468
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEI 906
+S+ V+ L + EY ++ G G S P L++ +PGP L + I
Sbjct: 17469 VTNSLK---VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNI 17525
Query: 907 LDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVT-LEYRVTGLTALTT 963
S+ V W P G + GY + E+ +R+ R + +T L RVTGLT
Sbjct: 17526 AKDSMTVCWNRPDSDGGSEIIGYIV--EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 17583
Query: 964 YTIEVAAMTSKGQGQVSASTI--SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGK 1020
Y V+A + G G+ S +T+ + P PGPPTN I + S+TL + +P YDG
Sbjct: 17584 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 17643
Query: 1021 TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG-- 1078
+ I ++VE + EEW ++ + R E+ L Y R+ +N VG
Sbjct: 17644 SEILGYVVEI---CKADEEEWQIVTPQTGLRVTR-FEISKLTEHQEYKIRVCALNKVGLG 17699
Query: 1079 --TSPPS--QPSRKIQTLQAPPDM-APANVSLRTASETSLWLRWMPLPEMEYNGNPESVG 1133
TS P +P K++ + D + +R + + + G P
Sbjct: 17700 EATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARI--------HIPFKGRPTP-- 17749
Query: 1134 YKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
+I +SR +G + + +I++ + + ++ N+ GS TV
Sbjct: 17750 -EITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTV--- 17805
Query: 1194 TRESVPSSG-PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL 1252
+ + + G P N++ S + W E P D V Y + +K T+ +
Sbjct: 17806 --KVLDTPGPPQNLAVKEVRKDSAFLVW-EPPIIDGGAKVKNYVI---DKRESTRKAYAN 17859
Query: 1253 VEGNSSR-SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPE 1311
V S+ S ++ L + +Y +V+A G G P + + P PP + +
Sbjct: 17860 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-PSPPGKVTLTD 17918
Query: 1312 VRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
V TS L+W+ P G +L Y + + T + E +A TGL
Sbjct: 17919 VSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNA---VVTGLSSGQE 17975
Query: 1371 YLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL----------- 1419
Y FR+ A KG + V K QP + ++A L
Sbjct: 17976 YQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPR 18035
Query: 1420 --LSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVK 1477
+SW DG P++ T E + LH N F K+ V
Sbjct: 18036 PNISWV--KDG-EPLKQTTRVNVEETATSTVLHIK--EGNKDDF----------GKYTVT 18080
Query: 1478 ATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGF 1537
ATN G + +E + + P P + V+I W+PPA
Sbjct: 18081 ATNSAGTA--TENLSVIVLEKPGPPVGPVRFDEV--SADFVVISWEPPA----------- 18125
Query: 1538 RIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRR 1594
Y G + + + + TW +++ + T ++ L
Sbjct: 18126 --------YTGGCQISNYIVEKRDTTTTTWHMVSATVAR--------TTIKITKLKTGTE 18169
Query: 1595 YEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQN 1653
Y+ R+ N G+ + V V P V + Q+ V W P D
Sbjct: 18170 YQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG-G 18228
Query: 1654 GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST 1713
I GY + E + L ++ + + K L Y V+A N G G S
Sbjct: 18229 TKIIGYHLEQKE-KNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18287
Query: 1714 PTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSK 1772
++ + P + +T +V + W+ P + G + GY + E DG +
Sbjct: 18288 VSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGY--IVEKKDLPDG--R 18343
Query: 1773 IVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPEIEANVTTGPGEGAPGPP 1828
+ V L E Y FR+ A+ F+ + +T AP
Sbjct: 18344 WMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNAS 18403
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
P +Y I +H +G+ +V+EA + + D++ KE+ M+
Sbjct: 18404 LDP---KYKDVIVVH--AGE-------TFVLEADIRGKPIPDVVWSKDGKELEETAARME 18451
Query: 1889 I 1889
I
Sbjct: 18452 I 18452
Score = 139 bits (350), Expect = 3e-32
Identities = 336/1554 (21%), Positives = 565/1554 (36%), Gaps = 218/1554 (14%)
Query: 378 FQCFARNAAGEVQ---TSTYLAVTSIAPN----ITRGPLDSTVID-GMSVVLACETSGAP 429
F+ A N AGE + T+ + T I I G D V G + + G P
Sbjct: 9474 FRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRP 9533
Query: 430 RPAITWQ---KGERILASGSVQLPRFTPLE----SGSLLISPTHISDAGTYTCLATNSRG 482
P +W+ K ++ + G +P LE S ++I S G Y+ A N G
Sbjct: 9534 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 9593
Query: 483 VDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVT-----HDPRVTIR-YIWEKDGA 536
A+ + V + PP+D V T+ S C ++ D I+ Y+ EK
Sbjct: 9594 QKTANCRVKVMD---VPGPPKDLKVSDITRGS--CRLSWKMPDDDGGDRIKGYVIEK--R 9646
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRV-----ISAGGNDSRSAHLRVRQLPH 591
T+ ++ ++ D + + + Y RV G R +
Sbjct: 9647 TIDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIY 9705
Query: 592 APEHPVAT-LSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLA-----SVD 644
P+ P+ + + + ++L+W P DG SP+ YI+E + T A D
Sbjct: 9706 PPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9765
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSK-----DTERVSLPE--------EPPT 691
+ TV+ LV Y+FR+ AVN G + S D +R +P E
Sbjct: 9766 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9825
Query: 692 APPQNVIASGRTNQSIMIQW-QPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
N++A + + W + PP+ N PV Y D VN
Sbjct: 9826 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-------------PVLY------DTHVN 9866
Query: 751 NLLLED---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ--GVPTVPPGNVHAEATNS 805
L+++D L+I + + Y + + E L G P P G + E+ ++
Sbjct: 9867 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSA 9926
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
+ +W P + G K+ + E+ E + + + L +
Sbjct: 9927 DQMTLSWFPPKD------DGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGH 9980
Query: 866 EYFTSVLCFTTPGDGPR--STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG 923
EY ++ G G S P+ R VPG + S + S+ V+W+EP G
Sbjct: 9981 EYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGG 10040
Query: 924 I-LTGYRIS--------WEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
+TGY + W+ NR + + + Y+VTGL + Y V A+ +
Sbjct: 10041 SPVTGYWLEMKDTTSKRWKRVNRDPIKAM----TLGVSYKVTGLIEGSDYQFRVYAINAA 10096
Query: 975 GQGQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQ 1031
G G S + ++ P PGPP +++ S L++ P DG + ++ ++VE +
Sbjct: 10097 GVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK 10155
Query: 1032 VGVVGEG-EEWLLIHQLSNEPDAR--SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
EG EEW + + + R + V L Y FR+R VNI G P + +
Sbjct: 10156 ----EEGKEEW----EKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV 10207
Query: 1089 IQ---TLQAPPDMAPANVSLRTASETS------LWLRWMPLPEMEYNGNPESVGYKIKYS 1139
I+ L +P A+V R ++ P P + +N N ++ +
Sbjct: 10208 IEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE---- 10263
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
+ + + I++ + + + A N +G +T++ + VP
Sbjct: 10264 ---------ATIETTAISSSMVIKNCQRSHQGVYSLLAKNE--AGERKKTIIVDVLD-VP 10311
Query: 1200 SSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW--LVEGNS 1257
T A T+ S + W PE D + Y + +E D R W + +
Sbjct: 10312 GPVGTPFLAHNLTNESCKLTWFS-PEDDGGSPITNYVIEKRESDR----RAWTPVTYTVT 10366
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTT 1315
++A + GL + Y ++ A IG G + ++ R VP P + EV
Sbjct: 10367 RQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKN 10426
Query: 1316 SVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
+V L W PP G I+ Y + RL T + T + L +R+YT GLK Y +
Sbjct: 10427 TVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLL--SRKYTVKGLKEGDTYEY 10484
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
R++A G G+ + T K D PP+ + D R + L+ G R
Sbjct: 10485 RVSAVNIVGQGKPSFCTKPITCK-DELAPPTLHL----DFRDK---LTIRVGEAFALTGR 10536
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND------IGDSEF 1487
Y + P W A V + + I K + K ++ + +S
Sbjct: 10537 Y---SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10593
Query: 1488 SEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYE 1547
S + + P +S T ++I W+PP +D + + I +E+ +
Sbjct: 10594 SRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG-GSKITNYIIEKKEVGKD 10652
Query: 1548 GLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGE 1607
W +T S + T ++ L + + Y R+ N G
Sbjct: 10653 ---------------VWMPVT--------SASAKTTCKVSKLLEGKDYIFRIHAENLYGI 10689
Query: 1608 GPSSPPQEVFVGE--AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
+ + VP AP +V T VTW P I Y + E
Sbjct: 10690 SDPLVSDSMKAKDRFRVPD-APDQPIVTEVTKDSALVTWNKP--HDGGKPITNYILEKRE 10746
Query: 1666 AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQA 1722
K ++ +L Y V+A N G G P S P + A
Sbjct: 10747 TMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIA 10806
Query: 1723 APSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGN 1781
PS P + + + T SV+++W+ P+ G + GY + Y+ D + +
Sbjct: 10807 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVG--DEEWRRANHTPESC 10864
Query: 1782 SPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
KV L +G TY+FR+ A GE P P++V+
Sbjct: 10865 PETKYKVTGLRDGQTYKFRVLA-------------VNAAGESDPAHVPEPVLVK 10905
Score = 138 bits (347), Expect = 7e-32
Identities = 278/1273 (21%), Positives = 477/1273 (37%), Gaps = 148/1273 (11%)
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNN 751
PPQ++ T S+ + W PP + I K YI+ + + + T+ +
Sbjct: 15649 PPQDLKVKEVTKTSVTLTWDPPLLDGGSKI-KNYIVEKRESTRKA---YSTVATNCHKTS 15704
Query: 752 LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
++ L +Y V A N G+G+ ++ E +PPG + ++ +
Sbjct: 15705 WKVDQLQEGCSYYFRVLAENEYGIGL-PAETAESVKASERPLPPGKITLMDVTRNSVSLS 15763
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSV 871
W P + I GY + ++ T T + + ++GL + EY V
Sbjct: 15764 WEKPEHDGGSRI-LGYIVEMQTKGSDKWATCATVK------VTEATITGLIQGEEYSFRV 15816
Query: 872 LCFTTPG-DGPRSTPQLVRTHEDVPGPVGHL---SFSEILDTSLKVSWQEPGEKNGILTG 927
G PR V + V P L +F+ + LKV G +T
Sbjct: 15817 SAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTW 15876
Query: 928 YR--ISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
++ + ++ R N T N L + + Y +++ S G+ + + I
Sbjct: 15877 HKDNVPLKQTTRVNAESTEN--NSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIV 15932
Query: 986 SGVPPELPGPPTN-LGISNIGPRSVTLQFRPG-YDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ PGPPT + + + S+TL + P YDG +SI+ ++VE + +
Sbjct: 15933 L----DKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR-------DTSTT 15981
Query: 1044 IHQLSNEPDARS-MEVPDLNPFTCYSFRMRQVNIVGTSP--PSQPSRKIQTLQAPPDMAP 1100
Q+ + AR+ ++ L Y FR+ N G S S+P+ + P
Sbjct: 15982 TWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGT 16041
Query: 1101 ANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV---E 1157
V+L +S S+ ++W E +G +GY ++ + ++ V ++ +
Sbjct: 16042 PVVTL--SSRDSMEVQWN---EPISDGGSRVIGYHLERKERN----SILWVKLNKTPIPQ 16092
Query: 1158 RDYTIEDLEEWTEYRVQVQAFNAIGSGP---WSQTVVGRTRESVPSSGPTNVSALATTSS 1214
+ LEE EY +V A N +G G S+ V R P P A+ T +
Sbjct: 16093 TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD----PCDPPGRPEAIIVTRN 16148
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA---------QLTG 1265
S+ ++W + P D + GY V KE L EG +++ ++TG
Sbjct: 16149 SVTLQWKK-PTYDGGSKITGYIVEKKE----------LPEGRWMKASFTNIIDTHFEVTG 16197
Query: 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI---WQ 1322
L + YE +V+A G S T D PP + P+ + T V ++
Sbjct: 16198 LVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFK 16257
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A G + + + +NTA +E+ + AT L + K
Sbjct: 16258 VDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF----ATSLSVKDAVRVDSGNYILKA 16313
Query: 1383 WGEAAE-ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSPVRYYTIQTR 1440
A E ++ V + DRP PP P+V V A L+W+P DG S + Y ++ R
Sbjct: 16314 KNVAGERSVTVNVKVLDRPGPPEGPVVIS-GVTAEKCTLAWKPPLQDGGSDIINYIVERR 16372
Query: 1441 ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
E W + A+V S V +L Y FR+ A N G E E +
Sbjct: 16373 ETSRLVWTVVDANVQ--TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFV 16430
Query: 1501 PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 1560
+AP VT T S+++ W+ PA D + IL G+ L +
Sbjct: 16431 VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL----------------GYVLEKRDKE 16474
Query: 1561 GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ--EVFV 1618
G W R + L + L ++ YE R+S NA G SPP +
Sbjct: 16475 GIRWTRC----HKRLIGELRL---RVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKAC 16527
Query: 1619 GEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
P N V T + + ++W P D +IQGY + + G T
Sbjct: 16528 DPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG-GCEIQGYIVEKCDVSVGEWTMCTPPT 16586
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ + +++++ L Y + A N AG G + A P V+ +L
Sbjct: 16587 GINKTNIEVEKLLEKHEYNFRICAINKAGVG----------EHADVPGPIIVE-EKLEAP 16635
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPC----------SPVDG-VSKIVTVDVKGN-SPLWL 1786
+++ E + N G ++ P VDG + +DV + + L L
Sbjct: 16636 DIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 16695
Query: 1787 KVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSS 1846
+ + Y + + T + V P P + + +++I W
Sbjct: 16696 DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSP----PVNLKVTEITKDSVSITWEP 16751
Query: 1847 G-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
G I Y++E R + + ++ + K ++ +D L+ G SY FRV A N+
Sbjct: 16752 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKN----SWKIDQLQEGCSYYFRVTAENE 16807
Query: 1906 YGFGTPSSPSQSV 1918
YG G P+ + +
Sbjct: 16808 YGIGLPAQTADPI 16820
Score = 130 bits (326), Expect = 2e-29
Identities = 330/1569 (21%), Positives = 558/1569 (35%), Gaps = 197/1569 (12%)
Query: 222 KNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV-LLSGGISDHNRR---LTIPNPTGS 277
K ++ AG S + V+ P + I W K G+ L S I D L +
Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPV---ITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 23205
Query: 278 DAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV-DIPCQAKGVP 336
DAG Y EA +S + V P VK E ++ + + +IP G P
Sbjct: 23206 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE--VSRDSVTITWEIPTIDGGAP 23263
Query: 337 PPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLA 396
+ K A + K T + + +ISGLV F+ N G +
Sbjct: 23264 VNNYIVEKREAAMRAFK-TVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE--- 23319
Query: 397 VTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA-------SGSVQL 449
TS A ++ PL ++ + V + T +P + G R+ +G+ +
Sbjct: 23320 -TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPL--YDGGSRLTGYVLEACKAGTERW 23376
Query: 450 PRFTPLESGSLLISPTHISDAGTYT--CLATNSRGVDEASA--------DLVVWARTRIT 499
+ L+ L + T +++ Y A N +GV E DL V ++
Sbjct: 23377 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23436
Query: 500 KPPQDQ-SVIKGTQASMVCGVTHDPRVTIRYIWE----KDGATLGTESHPRIRLDRNGSL 554
PQ V G +V + P + + ++ + E+H ++ L
Sbjct: 23437 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV-----AKL 23491
Query: 555 HISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTK 614
I +T D G YT + + G S + + + P P P+ + ++ +I ++W
Sbjct: 23492 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIK-IDEIDATSITISWEP 23550
Query: 615 P-FDGNSPLIRYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVG 672
P DG +PL Y++E + + P W + SV T L Y FR+ A N G
Sbjct: 23551 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFG 23608
Query: 673 KGQFSKDT-----ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYI 727
G + + + +P P T +V G T + W PP E + GYI
Sbjct: 23609 IGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMT-----LTWYPP-EDDGGSQVTGYI 23662
Query: 728 IRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTL 787
+ + + + L YE V A N+ G G S+ ++ +
Sbjct: 23663 VERKEVRADRWVRVNKVP-VTMTRYRSTGLTEGLEYEHRVTAINARGSGK-PSRPSKPIV 23720
Query: 788 QGVPTVPPG---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT 844
P PPG N T T++ W+ P + + + GY LI + + E T
Sbjct: 23721 AMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVT-GY-LIEMQKVDQHEWTKCN 23778
Query: 845 ARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFS 904
P I ++ L + EY VL G G + +VPG V
Sbjct: 23779 TTPT---KIREYTLTHLPQGAEYRFRVLACNAGGPGEPA---------EVPGTVKVTEML 23826
Query: 905 EILDTSLKVSWQE----------------PGEKNGILTGYRISWEEYNRTNTRVTHYLPN 948
E D L +QE G+ I + + R +
Sbjct: 23827 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE 23886
Query: 949 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRS 1008
+ ++ G + TY + + K + I S PE P L +I RS
Sbjct: 23887 LVIKEADRGDSG--TYDLVLENKCGKKAVYIKVRVIGSPNSPEGP-----LEYDDIQVRS 23939
Query: 1009 VTLQFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
V + +RP DG I +++E + W + + + S+ V L Y
Sbjct: 23940 VRVSWRPPADDGGADILGYILERREVPKAA---W---YTIDSRVRGTSLVVKGLKENVEY 23993
Query: 1068 SFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY 1125
FR+ N G S P + + +T PP+ + +++S+ L W +
Sbjct: 23994 HFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD--- 24050
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
+G GY I+ + K + H YT+ L EY+ ++ A N +G
Sbjct: 24051 DGGSRVTGYYIE-RKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSE 24109
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
+ P S+ VV + PS P + L+ + S+ ++W E PE D +LGY V Y++
Sbjct: 24110 TSPASEPVVCKDPFDKPSQ-PGELEILSISKDSVTLQW-EKPECDGGKEILGYWVEYRQS 24167
Query: 1243 DSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT-LDDVP 1301
D+ + E + + GL + YE +V A G P + +T L
Sbjct: 24168 -GDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGE 24226
Query: 1302 GPPMGILFPEVRTT---SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P + +V T + +L Q P I Y+ L + ++ R
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-----MSSDGR 24281
Query: 1359 QYTATGL--KPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416
+T T + + E ++ A G E + L++ + P P +
Sbjct: 24282 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYY------- 24334
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY---- 1472
G+ G + + R +P+ W H + N+ + ++ + +T
Sbjct: 24335 --------GAVGSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKN 24385
Query: 1473 --------KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
K++V+ +N G + + E +Q PD+ + + S +I W+P
Sbjct: 24386 VQRKTHAGKYKVQLSNVFGTVDAILDVE----IQDKPDKPTGPIVIEALLKNSAVISWKP 24441
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
PA+D + + + E GA W ++S S+T
Sbjct: 24442 PADDG-GSWITNYVVEKCEA--------------KEGAEWQLVSSAI--------SVTTC 24478
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT-----AAPRNVVVHGATATQ 1639
+ NL ++ Y R+S N G S P EV + + AP + T
Sbjct: 24479 RIVNLTENAGYYFRVSAQNTFG---ISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24535
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
V W+PP D I+ Y + E ++ N V T + E +KNL Y
Sbjct: 24536 CVVAWKPPASDG-GAKIRNYYLEKRE-KKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 24593
Query: 1700 VAAFNAAGD 1708
V N G+
Sbjct: 24594 VKCENLGGE 24602
Score = 128 bits (321), Expect = 7e-29
Identities = 170/673 (25%), Positives = 261/673 (38%), Gaps = 90/673 (13%)
Query: 1299 DVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
DVPGP + E V L W+ P G + + R + A S
Sbjct: 6783 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 6841
Query: 1359 QYTATGLKPESV-YLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
++T TGL+ V YLFR++A+ R G GE E V K D P PP + DV
Sbjct: 6842 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT--DVNR 6899
Query: 1416 RSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
V L+WEP DG + + Y I+ R+ S RW + + S+ + D ++ Y F
Sbjct: 6900 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEG-QEYSF 6958
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV+A N IG + S + + +P + L+ + T +SV ++W+PP +D + I
Sbjct: 6959 RVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPI 7018
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
L G+ + W P LT Y++ L K
Sbjct: 7019 L----------------GYIIERCEEGKDNWIRCNMKLV------PELT-YKVTGLEKGN 7055
Query: 1594 RYEIRMSVYNAVGEGPSSP------PQEVFVGEAVPTAAPRN---VVVHGATATQLDVTW 1644
+Y R+S N G S + FV + +A ++ V+V + T
Sbjct: 7056 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7115
Query: 1645 EPPPLDSQN-GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAF 1703
P P + GD K L + VK+K L+ Y ++S +
Sbjct: 7116 YPRPTATWCFGD--------------------KVLETGDR-VKMKTLSAYAELVISPSER 7154
Query: 1704 NAAGDGPRSTPTQGQTQQ--------AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-L 1754
+ G + +T A PSAP +KF ++T SV+++WE P G L
Sbjct: 7155 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7214
Query: 1755 EGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP---- 1810
GY + S K T + + L V DL +G Y F++ A+ GP
Sbjct: 7215 TGYVVEKREVS-----RKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARN-KCGPGEPA 7268
Query: 1811 EIEANVTTGPGEGAPGPP-GVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGL 1868
++ V P PP V R +++I + W + G I Y++E P
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7328
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYE 1928
W + V+ + L+ G Y +RV A+N G PS P++ + A E
Sbjct: 7329 W----VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7384
Query: 1929 EWWFLVVIALVGL 1941
FL V L GL
Sbjct: 7385 --IFLDVKLLAGL 7395
Score = 127 bits (320), Expect = 9e-29
Identities = 317/1464 (21%), Positives = 519/1464 (35%), Gaps = 187/1464 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVID------G 416
++ GL+ + F+ A N GE + LA + IA +I P LD T D G
Sbjct: 11560 RVPGLIEGNEYRFRIKAANIVGEGEPRE-LAESVIAKDILHPPEVELDVTCRDVITVRVG 11618
Query: 417 MSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
++ + G P P ITW K ++L ++ L L I +D G Y
Sbjct: 11619 QTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11677
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
A NS G + SA + V R P Q+ V T+ + C ++ WE
Sbjct: 11678 AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKEN--CTIS----------WENPLD 11722
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV---RQLPHAP 593
G+E I R + + WS T R+I A + + RV ++ P
Sbjct: 11723 NGGSEITNFIVEYRKPN---QKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGP 11779
Query: 594 ----EHPVATLSTVERRA--------------INLTWTKP-FDGNSPLIRYILEMSENNA 634
+ P+ ++ ++R + L W +P +DG SP + Y +E +
Sbjct: 11780 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11839
Query: 635 PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE---PPT 691
+ K T V V + Y+FR+ N+ G+ + K TE V + E+ P
Sbjct: 11840 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TEEVVVKEDLQKPVL 11898
Query: 692 APPQNVIASGRTNQSIM----IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
+ + + + +I ++ +P PE + L + K T A
Sbjct: 11899 DLKLSGVLTVKAGDTIRLEAGVRGKPFPE-------VAWTKDKDATDLTRSPRVKIDTRA 11951
Query: 748 DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
D + L + V A N+AG V + V G P N+ +S
Sbjct: 11952 DSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG----PVRNLKIVDVSSDR 12007
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W+ P + G ++ + E+ E MV + + V+ L + EY
Sbjct: 12008 CTVCWDPPED------DGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY 12061
Query: 868 FTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
V G GP S P + +T D PG +++ + V W P G
Sbjct: 12062 IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKS 12121
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS--AS 982
+TGY + +E + T + +V L Y V A G G+ S +
Sbjct: 12122 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 12181
Query: 983 TISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVE--AQVGVVGEGE 1039
+ + P E PGPPTN + + S+TL + +P YDG I ++VE ++ E
Sbjct: 12182 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDE 12241
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
W + + + + V L+ Y FR+ N VG P++ I+ + +
Sbjct: 12242 GWKRCNAAA-QLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI---LE 12297
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD 1159
P + L + + +R G P + ++ G+ V +V D
Sbjct: 12298 PPEIDLDASMRKLVIVR---------AGCPIRLFAIVR-------GRPAPKVTWRKVGID 12341
Query: 1160 YTIE----DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRES--------VPSSGP-TNV 1206
+ DL + + V + SG +S T+V E + + GP +++
Sbjct: 12342 NVVRKGQVDLVDTMAFLV-IPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 12400
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGL 1266
T +S V W+ PE D V Y V +E D T + S +T L
Sbjct: 12401 KVSDVTKTSCHVSWAP-PENDGGSQVTHYIVEKREADRKTWST--VTPEVKKTSFHVTNL 12457
Query: 1267 GKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
Y +V A G G P+ P+L P PP + E+ S L W PP
Sbjct: 12458 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 12517
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
G + IT E TGLK Y FR+ A+ G
Sbjct: 12518 LRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS 12577
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL-------------LSWEPGSDGLSP 1431
EA V E +++ PP M +Q ++A L W+ G D +
Sbjct: 12578 LPREAEGV-YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEV-- 12634
Query: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491
+ S A+H A ++S I+ + S + + A N G ++
Sbjct: 12635 ----------VTSSHLAVHKAD---SSSILIIKDVTRKDSGYYSLTAENSSG----TDTQ 12677
Query: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG 1551
+ + AP ++ + + W P ED + I
Sbjct: 12678 KIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNI----------------TN 12721
Query: 1552 FTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGP 1609
+ + + W +T++ S+ + T + L + Y R+ N G E
Sbjct: 12722 YIVEKCDVSRGDW--VTALASV------TKTSCRVGKLIPGQEYIFRVRAENRFGISEPL 12773
Query: 1610 SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQR 1668
+SP VP + P+N V + V W+ P DS G I GY I E +
Sbjct: 12774 TSPKMVAQFPFGVP-SEPKNARVTKVNKDCIFVAWDRP--DSDGGSPIIGYLIERKE-RN 12829
Query: 1669 GNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPS 1728
L + + L Y + A N AG P S PT+ T + P
Sbjct: 12830 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG 12889
Query: 1729 SVKFSELTTTSVNVSWEAPQFPNG 1752
+ ++T ++V++ W P+ G
Sbjct: 12890 KPEVIDVTKSTVSLIWARPKHDGG 12913
Score = 127 bits (319), Expect = 1e-28
Identities = 190/818 (23%), Positives = 304/818 (37%), Gaps = 69/818 (8%)
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER-DYTIEDLEEW-TEYRVQVQAFNAIGS 1183
+G + +GY ++ R D KT + DR E ++T+ L++ EY +V A N +G+
Sbjct: 6811 DGGSKIIGYVVE--RRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGT 6867
Query: 1184 GPWSQT---VVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYK 1240
G +T V R++ VP P NV+ + + W E PE D + Y + +
Sbjct: 6868 GEPVETDNPVEARSKYDVPGP-PLNVTITDVNRFGVSLTW-EPPEYDGGAEITNYVIELR 6925
Query: 1241 EKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDV 1300
+K S V SA +T + + Y +V A RIG G PS + D +
Sbjct: 6926 DKTSIRWDTAMTVRAEDL-SATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPI 6984
Query: 1301 --PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P PP+ + + +SV+L W+PP G + I R N +
Sbjct: 6985 ERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPEL 7044
Query: 1359 QYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE--DVRAR 1416
Y TGL+ + YL+R++A+ + G + +E L T +P ++ +V
Sbjct: 7045 TYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVP 7104
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFR 1475
+ + P + P + + L +G R + + S + ++ + +
Sbjct: 7105 NPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAY---AELVISPSERSDKGIYT 7161
Query: 1476 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 1535
+K N + S + A AP L T SV + W+PP +D L
Sbjct: 7162 LKLENRV-----KTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDG-GSPLT 7215
Query: 1536 GFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRY 1595
G+ + RE+ + TW ++ + + P L Q + Y
Sbjct: 7216 GYVVEKREVSRK---------------TWTKVMDFVTDLEFTVPDLVQ--------GKEY 7252
Query: 1596 EIRMSVYNAVGEGPSS---PPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQ 1652
++ N G G + P + VP P NV TA + +TW+PP D
Sbjct: 7253 LFKVCARNKCGPGEPAYVDEPVNMSTPATVPDP-PENVKWRDRTANSIFLTWDPPKNDG- 7310
Query: 1653 NGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712
I+GY + RG+ +AE +++ L Y V A N G S
Sbjct: 7311 GSRIKGYIVE--RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPS 7368
Query: 1713 TPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDG 1769
PT Q Q AP VK T E P G E ++ + +
Sbjct: 7369 RPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP-KITWTKADMILK 7427
Query: 1770 VSKIVTVD-VKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPP 1828
K +T++ V S + + ++ TY +E NV PG P
Sbjct: 7428 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGP----PA 7483
Query: 1829 GVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSM 1887
I + + + W+ D G IT YV+E R +D +W L V F
Sbjct: 7484 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL----SSTVKDTNFKA 7539
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
L P Y FRV A N YG G P S + +P
Sbjct: 7540 TKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDP 7577
Score = 124 bits (311), Expect = 1e-27
Identities = 299/1315 (22%), Positives = 478/1315 (36%), Gaps = 170/1315 (12%)
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
VS+ + P PP N + S++ +W+PP + + I I Y L + K
Sbjct: 8491 VSVLDTP--GPPINFVFEDIRKTSVLCKWEPPLDDGGSEI-----INYTL-------EKK 8536
Query: 743 NITDADVNNLLLED-----------LIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQG 789
+ T D +++ LI Y V A N G G S + G
Sbjct: 8537 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFG 8596
Query: 790 VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN- 848
P P + + T+++ + WN P + G ++ + E+ E + +R N
Sbjct: 8597 PPDAPDKPIVEDVTSNSML-VKWNEPK-------DNGSPILGYWLEKREVNSTHWSRVNK 8648
Query: 849 -FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
+++ V GL + Y V G G S P +T D P G +
Sbjct: 8649 SLLNALKAN-VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGP-PIPRVT 8706
Query: 908 DTS---LKVSWQEPG-EKNGILTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTAL 961
DTS +++ W+ P G + GY + ++ TN +R T + V +Y V +
Sbjct: 8707 DTSSTTIELEWEPPAFNGGGEIVGYFVD-KQLVGTNEWSRCTEKMIKVR-QYTVKEIREG 8764
Query: 962 TTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV----TLQFRPGY 1017
Y + V+A+ + G+G + + P+ P P L +S G + TL+
Sbjct: 8765 ADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP-PAVELDVSVKGGIQIMAGKTLRIPAVV 8823
Query: 1018 DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G+ V +V EGE + N + + D + + N
Sbjct: 8824 TGRP------VPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSC 8877
Query: 1078 GTSPPSQPSRKIQTLQAPP---DMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY 1134
G+ + +++ P D+ P + L W + E +G E G+
Sbjct: 8878 GSK---FAAARVEVFDVPGPVLDLKPV-----VTNRKMCLLNWS---DPEDDGGSEITGF 8926
Query: 1135 KIKYSRSDGHGKTLSHVVQ-DRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
I+ R D T ++ +R + D T L E EY+ +V A N G GP +G
Sbjct: 8927 IIE--RKDAKMHTWRQPIETERSKCDIT--GLLEGQEYKFRVIAKNKFGCGP--PVEIGP 8980
Query: 1194 TRESVPSSGPTNVSALA---TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRF 1250
P PT+ L T S++ + W E P ++ + GY + EK +P F
Sbjct: 8981 ILAVDPLGPPTSPERLTYTERTKSTITLDWKE-PRSNGGSPIQGYII---EKRRHDKPDF 9036
Query: 1251 WLVEGN--SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGIL 1308
V + S + L ++ +YE +V A IG+ PS P L + D PP L
Sbjct: 9037 ERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLP--LNVVIQDDEVPPTIKL 9094
Query: 1309 FPEVRTTSVRL-IWQP---PAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
VR ++++ +P PA G+ + +I N T T + L + + + +
Sbjct: 9095 RLSVRGDTIKVKAGEPVHIPADVTGLPMP-KIEWSKNETVIEKPT-DALQITKEEVSRSE 9152
Query: 1365 LK-----PESVY----LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRA 1415
K P++V + +TA R G + V E DRP PP V D++A
Sbjct: 9153 AKTELSIPKAVREDKGTYTVTASNRLG----SVFRNVHVEVYDRPSPPRNLAVT--DIKA 9206
Query: 1416 RSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S L+W+ P +G S + +Y I R+ + + + + + +L P Y+F
Sbjct: 9207 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 9266
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGIL 1534
RV+A N G S+ + + + P V T S+L+ W PP D +
Sbjct: 9267 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSPI 9325
Query: 1535 LGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSL--TQYELDNLNKH 1592
G+ + RE EG + S S +++ L ++ + L +
Sbjct: 9326 TGYWLEKRE---EG----------------SPYWSRVSRAPITKVGLKGVEFNVPRLLEG 9366
Query: 1593 RRYEIRMSVYNAVGEGPSSPPQ--EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+Y+ R NA G GP S P EV P P V T + + + W+PP D
Sbjct: 9367 VKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKD 9426
Query: 1651 SQNGDIQGYKIYFWE---AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG 1707
I+GY + E + E K + E V NL Y V A N AG
Sbjct: 9427 G-GSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVV--PNLKELRKYRFRVKAVNEAG 9483
Query: 1708 DGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
+ S T Q P + + P G R +
Sbjct: 9484 ESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG-----RPTPKSS 9538
Query: 1765 SPVDGVSKIVTVDVKGNSP-----------LWLKVKDLAEGVTYRFRIRAKTFTYGPEIE 1813
DG +K D + P + + + T ++ I AK
Sbjct: 9539 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 9598
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGLWDIL 1872
V G P V I R S ++ W D G I YVIE R D W
Sbjct: 9599 CRVKVMDVPGPPKDLKVSDITRGSCRLS--WKMPDDDGGDRIKGYVIEKRTIDGKAW--- 9653
Query: 1873 IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFY 1927
+ + S TF + L Y FRV A N +G G P Q A+ +P Y
Sbjct: 9654 -TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR--DPIY 9705
Score = 122 bits (307), Expect = 3e-27
Identities = 293/1394 (21%), Positives = 498/1394 (35%), Gaps = 169/1394 (12%)
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P T T + + +L W+ P DG S + YI+E E + + T
Sbjct: 10116 PPGPPFPKVTDWT--KSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10173
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ V GL Y+FR+ AVN G G+ + T+ + + + +P + AS R +
Sbjct: 10174 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-VSPDLQLDASVRDRIVV- 10231
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLP---VGYQFKNIT---DADVNNLLLEDLIIWTN 762
H G+++ II Y ++G P V + T +A + + ++ N
Sbjct: 10232 ---------HAGGVIR--IIAY-VSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKN 10279
Query: 763 YE------IEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
+ + A N AG + V + G P P H TN + + TW +P
Sbjct: 10280 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAH-NLTNESC-KLTWFSPE 10336
Query: 817 PQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
+ I Y + E ++ VT R N V GL + YF +
Sbjct: 10337 DDGGSPITN-YVIEKRESDRRAWTPVTYTVTRQN-------ATVQGLIQGKAYFFRIAAE 10388
Query: 875 TTPGDGP---RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG------IL 925
+ G GP S ++R VP L E+ ++ ++W P G +L
Sbjct: 10389 NSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 10448
Query: 926 TGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
I E++++ TN + ++ +Y V GL TY V+A+ GQG+ S T
Sbjct: 10449 ESRLIGTEKFHKVTNDNL------LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTK 10502
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFRPG--------YDGKTSISRWLVEAQVGVVG 1036
EL P +L + L R G Y GK + + V+
Sbjct: 10503 PITCKDELAPPTLHLDFRD------KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556
Query: 1037 EGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP- 1095
+ + P ++E + + N G+ + ++ + P
Sbjct: 10557 DDRT-----HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSR---KGFCQVNVVDRPG 10608
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL-SHVVQD 1154
P + P VS ++ + + W P + +G + Y I+ GK + V
Sbjct: 10609 PPVGP--VSFDEVTKDYMVISWKPPLD---DGGSKITNYIIEKKEV---GKDVWMPVTSA 10660
Query: 1155 RVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTRESVPSSGPTNVSALATT 1212
+ + L E +Y ++ A N G S P S ++ + R VP + P T
Sbjct: 10661 SAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDA-PDQPIVTEVT 10719
Query: 1213 SSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLY 1272
S LV W++ + + + Y + +E S R + ++ L + Y
Sbjct: 10720 KDSALVTWNKPHDGGKP--ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 10777
Query: 1273 EVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
E +V A IG G PS P P+ + P PP+ + SV L WQPP G
Sbjct: 10778 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10837
Query: 1331 -ILAYQITH-RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE 1388
IL Y + + ++ A + +Y TGL+ Y FR+ A G + A
Sbjct: 10838 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 10897
Query: 1389 ALVVTTEKRDRPQPPS----RPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPS 1444
K DR +PP M +++ ++ L LS + I+ P
Sbjct: 10898 VPEPVLVK-DRLEPPELILDANMAREQHIKVGDTLR--------LSAI----IKGVPFPK 10944
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIG------DSEFSEESESLTTLQ 1498
W A +D + + R A D G ++ ++ S+ L
Sbjct: 10945 VTWKKEDRDAPTKAR---IDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV 11001
Query: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558
P L V+ S + W+ P +D ++ + + R++
Sbjct: 11002 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDG-GSVITNYVVERRDVA------------- 11047
Query: 1559 NPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP--SSPPQEV 1616
A W+ L++ ++ + +LN+ +Y R++ N G GP +P
Sbjct: 11048 --SAQWSPLSATSKKKS--------HFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIK 11097
Query: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVK 1676
+ P P+++ T++ + W P D I GY + E Q + +K
Sbjct: 11098 ALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDG-GSPITGYLV---EYQEEGTQDWIK 11153
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST--PTQGQTQQAAPSAPSSVKFSE 1734
+ + L Y V A N G G T P + Q + PS VK E
Sbjct: 11154 FKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIE 11213
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+ P G+ S + + TV+ S + L +K+
Sbjct: 11214 GLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTVETDNFSSV-LTIKNCLRR 11271
Query: 1795 VTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGK 1851
T ++I + ++T PGPP PI + + + I W D G
Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTV---LDVPGPPTGPINILDVTPEHMTISWQPPKDDGG 11328
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
P+ Y++E + + + W + + S + L+ G Y FRV A N G G P
Sbjct: 11329 SPVINYIVEKQDTRKDTWGV----VSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPP 11384
Query: 1912 SSPSQSVPAQKANP 1925
+ +V K +P
Sbjct: 11385 LDSTPTVAKHKFSP 11398
Score = 119 bits (299), Expect = 2e-26
Identities = 335/1620 (20%), Positives = 584/1620 (36%), Gaps = 266/1620 (16%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAK--------GVPPPSITWYKDAAVVEVEK 353
++ +EP + ++ P+ + +++K V I A G PPP ITW K +
Sbjct: 23127 IAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA 23186
Query: 354 LTRFRQRNDGGLQISGLVPD-----DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP 408
+ D S L+ D D G + A N +G+ + + V T GP
Sbjct: 23187 II------DTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD-----TPGP 23235
Query: 409 LDSTVI-----DGMSVVLACET--SGAPRPAITWQKGER-------ILASGSVQLPRFTP 454
S + D +++ T GAP +K E + S L R +
Sbjct: 23236 CPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISG 23295
Query: 455 LESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQAS 514
L G++ + L N G+ E + + P V+ T++
Sbjct: 23296 LVEGTMYY----------FRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKS- 23344
Query: 515 MVCGVTHDPRVTIRYIWEK---DGAT-----------LGTESHPRIRLDRNGSLHISQTW 560
T+ WEK DG + GTE ++ + L + T
Sbjct: 23345 -----------TVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTS 23393
Query: 561 SGDIGTYTCRVISA---GGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD 617
+ Y R+ + G ++ R V + P LST+ ++ I++ +P +
Sbjct: 23394 LNEGEQYLFRIRAQNEKGVSEPRETVTAVT-VQDLRVLPTIDLSTMPQKTIHVPAGRPVE 23452
Query: 618 GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGK---- 673
L+ I A W S ++ VTV+ R + D G+
Sbjct: 23453 ----LVIPIAGRPPPAASW-FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23507
Query: 674 -----GQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII 728
G S+ + + L + P P + T SI I W+PP E L GY++
Sbjct: 23508 LKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDAT--SITISWEPP-ELDGGAPLSGYVV 23564
Query: 729 RYCLAG----LPVG-------YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
A LPV ++F +T+ + Y VAA N G+G
Sbjct: 23565 EQRDAHRPGWLPVSESVTRSTFKFTRLTEGN-------------EYVFRVAATNRFGIGS 23611
Query: 778 Y-SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGY-------KL 829
Y S+V E PP + + + TW P + + GY +
Sbjct: 23612 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRA 23670
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
W + VTM R +GL + EY V G G S P
Sbjct: 23671 DRWVRVNKVPVTMTRYRS-----------TGLTEGLEYEHRVTAINARGSGKPSRPSKPI 23719
Query: 890 THEDVPGPVGHLSFSEILDT---SLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
D P G + DT S+ ++W P ++ G +TGY I ++ ++ +
Sbjct: 23720 VAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT 23779
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLG----- 1000
P EY +T L Y V A + G G+ + + V L P L
Sbjct: 23780 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 23839
Query: 1001 ---ISNIGPRSVTLQFRPGYDGKT-SISRWLVEAQ------VGVVGEGEEWLLIHQLSNE 1050
+ G +T+ + GK I +W E Q + E L+I + ++
Sbjct: 23840 GIFVRQGGVIRLTIPIK----GKPFPICKWTKEGQDISKRAMIATSETHTELVIKE-ADR 23894
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110
D+ + ++ N + ++ V ++G+ P+ P ++ ++ +R
Sbjct: 23895 GDSGTYDLVLENKCGKKAVYIK-VRVIGS--PNSPEGPLEY---------DDIQVR---- 23938
Query: 1111 TSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE-RDYTIEDLEEWT 1169
S+ + W P + +G + +GY ++ K + + RV ++ L+E
Sbjct: 23939 -SVRVSWRPPAD---DGGADILGYILERREVP---KAAWYTIDSRVRGTSLVVKGLKENV 23991
Query: 1170 EYRVQVQAFNAIG-SGPWS--QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 1226
EY +V A N G S P + V +T + P L T SS+ + WS P+
Sbjct: 23992 EYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSR-PKD 24050
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG--D 1284
D V GY + KE +D R + ++ +TGL Y+ +++A +G +
Sbjct: 24051 DGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYT-VTGLVPDAEYQFRIIAQNDVGLSE 24109
Query: 1285 GSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTT 1343
SP+ P++ + D P P + + SV L W+ P G IL Y + +R +
Sbjct: 24110 TSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGD 24169
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE-ALVVTTEKRDRPQP 1402
+A + + +Q+T GL + Y FR+ A+ G A+ + T+ P
Sbjct: 24170 SAWKKSNKERIKD-KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP 24228
Query: 1403 PSRPMVQQEDVR-ARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF 1461
R ++ + + LS + L +++Y + S ++ + S +H +
Sbjct: 24229 GIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVM 24288
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 1521
++ + ATN++G+ E S S LQA P P
Sbjct: 24289 TEEQEDEGV---YTCIATNEVGEVETS----SKLLLQATPQFHPGY-------------- 24327
Query: 1522 WQPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATWAELTSMY-SMR 1574
P ++K Y G G TLR G P TW + +
Sbjct: 24328 ---PLKEK----------------YYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24368
Query: 1575 NLSRPSLTQYE---LDNLNKHR---RYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPR 1628
N++ + Y + N+ + +Y++++S N G + E+ PT
Sbjct: 24369 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLS--NVFGTVDAILDVEIQDKPDKPTGP-- 24424
Query: 1629 NVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLK 1688
+V+ ++W+PP D I Y + EA+ G + V + ++ + ++
Sbjct: 24425 -IVIEALLKNSAVISWKPPA-DDGGSWITNYVVEKCEAKEGAEWQLVSSA-ISVTTCRIV 24481
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPR---STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
NLT Y V+A N G S+ ++ P AP + +T S V+W+
Sbjct: 24482 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK 24541
Query: 1746 APQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
P G + Y L +K ++V + VK+L EG+ Y FR++ +
Sbjct: 24542 PPASDGGAKIRNYYLEKREKKQ----NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCE 24597
Score = 115 bits (288), Expect = 5e-25
Identities = 161/653 (24%), Positives = 252/653 (38%), Gaps = 89/653 (13%)
Query: 1299 DVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN--TATVEVLAP 1355
D PGPP ++ + L W P G + I + + + + TA V
Sbjct: 12685 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKT 12744
Query: 1356 SARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP---PSRPM-VQQE 1411
S R L P Y+FR+ A+ R G E +T+ K P PS P +
Sbjct: 12745 SCR---VGKLIPGQEYIFRVRAENRFGISEP-----LTSPKMVAQFPFGVPSEPKNARVT 12796
Query: 1412 DVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFT 1470
V + ++W+ P SDG SP+ Y I+ +E S W + ++ + + + L
Sbjct: 12797 KVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRS-TEYPCAGLVEGL 12855
Query: 1471 SYKFRVKATNDIGDSEFSEESESLTT-LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK 1529
Y FR+ A N G S S+ +E +T + P P ++ VT T + + W P D
Sbjct: 12856 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLI---WARPKHDG 12912
Query: 1530 INGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQ--YELD 1587
+ I+ G+ + PG W N + + Q Y
Sbjct: 12913 GSKII----------------GYFVEACKLPGDKWVRC-------NTAPHQIPQEEYTAT 12949
Query: 1588 NLNKHRRYEIRMSVYNAVGEGPSSPPQE--VFVGEAVPTAAPRNVV------VHGATATQ 1639
L + +Y+ R AV P S P + + E VP +V V T
Sbjct: 12950 GLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVC 13009
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
LD T P+ + + G + E + + + TL L SV K+ YT
Sbjct: 13010 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGDYT----- 13062
Query: 1700 VAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
+ A N++G + + + P P+SVK +++ + +SWE P G + Y
Sbjct: 13063 ITAENSSGSKSATIKLKVLDK---PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG--------P 1810
+ S + TV + S V+ L EG Y+FRI A+ YG P
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCS-----VEKLIEGHEYQFRICAEN-KYGVGDPVFTEP 13173
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSA-IAIHWSS-GDPGKGPITRYVIEARPSDEGL 1868
I N PG P P+I + + + W D G PIT Y++E R +
Sbjct: 13174 AIAKNPYDPPGRCDP-----PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 13228
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
W + + K + T L+ G Y+FRV A+N G G PS S++ A+
Sbjct: 13229 WTKVNR---KPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYAR 13278
Score = 114 bits (285), Expect = 1e-24
Identities = 351/1625 (21%), Positives = 576/1625 (35%), Gaps = 260/1625 (16%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARN 384
V+IP G P P++TW K +++ + F L I+ V D+G + ARN
Sbjct: 14780 VEIP--VLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14837
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILAS 444
GEV + V I P GP+ + V +W E
Sbjct: 14838 IVGEVGDVITIQVHDI-PGPPTGPIKFDEVSSDFV------------TFSWDPPEN---D 14881
Query: 445 GSVQLPRF----------TPLESGSLLISPTHISDAGT------YTCLATNSRGVDE--A 486
G V + + T +E + +I T+ + T + A N GV
Sbjct: 14882 GGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 14941
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
SA +V ++ PP V T+ SM H+P DG + H
Sbjct: 14942 SACIVANYPFKVPGPPGTPQVTAVTKDSMTIS-WHEPL--------SDGGSPILGYHVE- 14991
Query: 547 RLDRNGSLHISQTWS-----GDIGTYTCRVISAGGNDSRSAHLRV-------RQLPHAPE 594
R +RNG L QT S G+I S+G D + RV + P P
Sbjct: 14992 RKERNGILW--QTVSKALVPGNI------FKSSGLTDGIAYEFRVIAENMAGKSKPSKPS 15043
Query: 595 HPVATLSTVE-----------RRAINLTWTKP-FDGNSPLIRYILEMSE-NNAPWTVLLA 641
P+ L ++ R + L W KP + G + YI+E + N W
Sbjct: 15044 EPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 15103
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
S + TV GL +Y+FR+ A N G + + AP V
Sbjct: 15104 S-NILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKF 15162
Query: 702 RTNQSIM----------IQWQPPPE---SHQNGILKGYIIRYCLAGLPVGYQFKNITDAD 748
+ + + +PPP S L+G A L + I D
Sbjct: 15163 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEG------TAKLEI-----KIADFS 15211
Query: 749 VNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
NL+ +D + + A N G +++ KV + P P G + S
Sbjct: 15212 -TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLD-----RPGPPEGPLAVTEVTSE 15265
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTE 866
+W P + G K+ + ++ E + + + V+ L K E
Sbjct: 15266 KCVLSWFPPLD------DGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 15319
Query: 867 YFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y V+ G G S P L P P + + I S+ V W P G
Sbjct: 15320 YIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS 15379
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + + + L Y+V+GLT Y + A + G +SA +
Sbjct: 15380 EIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAG---ISAPS 15436
Query: 984 ISSGVPPEL-----PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+S PGPP N + + S+++ + +P YDG + I+ ++VE + E
Sbjct: 15437 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEI---ALPE 15493
Query: 1038 GEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPS--QPSRKIQTLQAP 1095
+EW ++ + A S + L Y R+ +N G P+ + K + P
Sbjct: 15494 EDEWQIVTPPAG-LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 15552
Query: 1096 PDM-----APANVSLRTASETSLW--LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
P++ V++R L+ ++ P PE +K++R HG++L
Sbjct: 15553 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-------------VKWARD--HGESL 15597
Query: 1149 SHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSA 1208
+IE +T + V N SG + TV S S NV
Sbjct: 15598 DKA---------SIESTSSYT--LLIVGNVNRFDSGKYILTV---ENSSGSKSAFVNVRV 15643
Query: 1209 LAT------------TSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN 1256
L T T +S+ + W + P D + Y V EK T+ + V N
Sbjct: 15644 LDTPGPPQDLKVKEVTKTSVTLTW-DPPLLDGGSKIKNYIV---EKRESTRKAYSTVATN 15699
Query: 1257 SSRSA-QLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT 1315
+++ ++ L + Y +VLA G G P+ + + P PP I +V
Sbjct: 15700 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA-SERPLPPGKITLMDVTRN 15758
Query: 1316 SVRLIWQPPAAPNGI-ILAY--QITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
SV L W+ P G IL Y ++ + + A ATV+V + T TGL Y
Sbjct: 15759 SVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKV-----TEATITGLIQGEEYS 15813
Query: 1373 FRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-------VQQEDVRARSVLLSWEPG 1425
FR++AQ KG + + L V +D PP+ + + ED++ +
Sbjct: 15814 FRVSAQNEKGISDPRQ-LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG---- 15868
Query: 1426 SDGLSPVRYYTIQTRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGD 1484
P T +P + +++ S +N+ I D + + + VK TN G
Sbjct: 15869 ----RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGH-YVVKLTNSAG- 15922
Query: 1485 SEFSEESESLTTLQAAPDEAPT-ILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRE 1543
E E+L + PT + + T S+ + W PP D + I
Sbjct: 15923 ----EAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSI---------- 15968
Query: 1544 LLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
+ + + TW +++ + T + L Y+ R++ N
Sbjct: 15969 ------NNYIVEKRDTSTTTWQIVSATVAR--------TTIKACRLKTGCEYQFRIAAEN 16014
Query: 1604 AVGEGP--SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKI 1661
G+ +S P VP P VV ++ ++V W P D + GY +
Sbjct: 16015 RYGKSTYLNSEPTVAQYPFKVP-GPPGTPVVTLSSRDSMEVQWNEPISDG-GSRVIGYHL 16072
Query: 1662 YFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQ 1721
E + L ++ + + K L Y V+A N G G S ++ +
Sbjct: 16073 ERKE-RNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVAR 16131
Query: 1722 AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKG 1780
P + +T SV + W+ P + G + GY +V + P K ++
Sbjct: 16132 DPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGY-IVEKKELPEGRWMKASFTNIID 16190
Query: 1781 NSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTG--PGEGAPGPPGVPIIVRYSS 1838
+V L E Y FR+ A+ G E + +TG PP + + +Y
Sbjct: 16191 TH---FEVTGLVEDHRYEFRVIARN-AAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16246
Query: 1839 AIAIH 1843
I +H
Sbjct: 16247 TIVVH 16251
Score = 105 bits (263), Expect = 4e-22
Identities = 280/1353 (20%), Positives = 493/1353 (36%), Gaps = 159/1353 (11%)
Query: 621 PLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT 680
P + + + +AP T V P + + ++ + L N G S
Sbjct: 10941 PFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSV-- 10997
Query: 681 ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQ 740
+V + ++P PP+++ S S + W+ P + + I + R +A Q
Sbjct: 10998 -KVLVLDKP--GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASA----Q 11050
Query: 741 FKNIT-DADVNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGN 797
+ ++ + + + L Y VAA N G G V + K + P PP +
Sbjct: 11051 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11110
Query: 798 VHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF 857
+H + T + WN P + I GY L+ ++ E ++ N +
Sbjct: 11111 LHHVDVDKTEVSLVWNKPDRDGGSPIT-GY-LVEYQEEGTQDWIKFKTVTNLEC-----V 11163
Query: 858 VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVS--- 914
V+GL++ Y V G G T + E + P L I +K
Sbjct: 11164 VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTV 11223
Query: 915 ---------------WQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLT 959
W G + Y + + ++ T + + L T EY++T
Sbjct: 11224 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT-IKNCLRRDTGEYQITVSN 11282
Query: 960 ALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN-LGISNIGPRSVTLQFRPGYD 1018
A + T+ V ++PGPPT + I ++ P +T+ ++P D
Sbjct: 11283 AAGSKTVAVHLTVL-----------------DVPGPPTGPINILDVTPEHMTISWQPPKD 11325
Query: 1019 -GKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G + + ++VE Q + W ++ S++ +++P L Y FR+R N +
Sbjct: 11326 DGGSPVINYIVEKQDT---RKDTWGVVSSGSSKT---KLKIPHLQKGCEYVFRVRAENKI 11379
Query: 1078 GTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIK 1137
G PP + + + P P + +E + + W LP+ + G GY ++
Sbjct: 11380 GVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSD--GGSPITGYYME 11436
Query: 1138 YSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTR 1195
R + GK + + + + L E Y +V A N G S P S + R
Sbjct: 11437 --RREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR 11494
Query: 1196 ESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG 1255
P P N + + + W++ P +D +LGY V ++ + R E
Sbjct: 11495 PIKPPGPPINPKLKDKSRETADLVWTK-PLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11553
Query: 1256 NSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVR 1313
+ ++ GL + Y ++ A +G+G P ++ + + P + + +V
Sbjct: 11554 IRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVI 11613
Query: 1314 TT----SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPES 1369
T ++R++ + P I + ++ ++ L Q
Sbjct: 11614 TVRVGQTIRILARVKGRPEPDI-TWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672
Query: 1370 VYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDG 1428
Y+ I+A+ G + + + V DRP P V +V + +SWE P +G
Sbjct: 11673 KYI--ISAKNSSGHAQGSAIVNVL----DRPGPCQNLKVT--NVTKENCTISWENPLDNG 11724
Query: 1429 LSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 1488
S + + ++ R+ W++ ++ V+ I L Y FRV A N +G
Sbjct: 11725 GSEITNFIVEYRKPNQKGWSIVASDVTKR---LIKANLLANNEYYFRVCAENKVGVGPTI 11781
Query: 1489 EESESLTTLQAA--PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLY 1546
E + + P E P L + T V ++W+ P D L + + R
Sbjct: 11782 ETKTPILAINPIDRPGE-PENLHIADKGKTFVYLKWRRPDYDG-GSPNLSYHVERR---- 11835
Query: 1547 EGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG 1606
L+G ++ W E S++ T Y +D +++ YE R+ N G
Sbjct: 11836 -------LKGSDD----W-ERVHKGSIKE------THYMVDRCVENQIYEFRVQTKNEGG 11877
Query: 1607 EGPSSPPQEVFVGEAVPT-------AAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGY 1659
E +EV V E + + V + V +P P + D
Sbjct: 11878 ESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDAT 11937
Query: 1660 KIYFWEAQRGNLTERVKTLFLAENS----VKLKNLTGYTAYMVSVAAFNAAGDGPRSTPT 1715
+ + RVK A++S K K G Y+V+ A N AG
Sbjct: 11938 DL--------TRSPRVKIDTRADSSKFSLTKAKRSDG-GKYVVT--ATNTAGSFVAYATV 11986
Query: 1716 QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV--SKI 1773
+ P ++K ++++ V W+ P+ G E + E C V +
Sbjct: 11987 NVLDK---PGPVRNLKIVDVSSDRCTVCWDPPEDDGGC-EIQNYILEKCETKRMVWSTYS 12042
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGE----GAPGPP 1828
TV G + V L EG Y FR+RA+ GP E+ + G P PP
Sbjct: 12043 ATVLTPGTT-----VTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPP 12097
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
V + + + + D GK IT Y +E + W + K + +
Sbjct: 12098 EVTKVSKEEMTVVWNPPEYDGGKS-ITGYFLEKKEKHSTRWVPVNKSA---IPERRMKVQ 12153
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
L P Y FRV A N+ G G PS PS+ V A+
Sbjct: 12154 NLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 12186
Score = 100 bits (248), Expect = 2e-20
Identities = 154/690 (22%), Positives = 263/690 (38%), Gaps = 56/690 (8%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRA- 134
+ +TSLD +R +N++G + + + E E S + ++RA
Sbjct: 12257 FTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAG 12316
Query: 135 ------PRIASFPQPQVTWFRDG--RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAV 186
+ P P+VTW + G + + LVI ++ D+G+Y + V
Sbjct: 12317 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLV 12376
Query: 187 NDKNGDNKTSQPITLTVENVGGPADPIAPTIII---------PPKNTSVVAGTSEVTLEC 237
N + + + + V + GP + + + PP+N T + +
Sbjct: 12377 NPAG---EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKR 12433
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI--SDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPS 295
A+ + + KK ++ + +++ R+T N G + VL S
Sbjct: 12434 EADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP--- 12490
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPS--ITWYKDAAVVEVEK 353
LS +PP+ ++ E +T + +P G IT Y++ ++
Sbjct: 12491 ------LSEPDPPRKLEVTE--MTKNSATLAWLPPLRDGGAKIDGYITSYREEEQ-PADR 12541
Query: 354 LTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIAPNITRGPL 409
T + D L ++GL F+ ARNA G Y A + P P
Sbjct: 12542 WTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPE 12601
Query: 410 DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
T+ G + + G P P W+KGE + + S L S L+I D
Sbjct: 12602 QITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS-HLAVHKADSSSILIIKDVTRKD 12660
Query: 470 AGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--I 527
+G Y+ A NS G D +VV +PP D S I S+ + + +
Sbjct: 12661 SGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 12720
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG-NDSRSAHLRV 586
YI EK + G + + S + + G + R + G ++ ++ V
Sbjct: 12721 NYIVEKCDVSRGDWVTALASVTKT-SCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 12779
Query: 587 RQLPHA-PEHPV-ATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
Q P P P A ++ V + I + W +P DG SP+I Y++E E N+ V
Sbjct: 12780 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 12839
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS--LPEEPPTAPPQNVIASG 701
++T GLV Y FR+ A+N G SK TE V+ +P +PP P +
Sbjct: 12840 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDV--- 12896
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYC 731
T ++ + W P + I+ GY + C
Sbjct: 12897 -TKSTVSLIWARPKHDGGSKII-GYFVEAC 12924
Score = 94.0 bits (232), Expect = 1e-18
Identities = 163/705 (23%), Positives = 268/705 (38%), Gaps = 83/705 (11%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHA-----------GFY 89
G L+C G + KW +EL + +Y ++S RTH G Y
Sbjct: 24242 GEAAQLSCQIVGRPLPDIKWYRFGKELIQ---SRKYKMSSDGRTHTLTVMTEEQEDEGVY 24298
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASF--PQPQVTW 147
CI N +G + + +++ + F G + +G + P P +TW
Sbjct: 24299 TCIATNEVGEV-ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTW 24357
Query: 148 FRDGRKIPPSSRIAITLENTLVILSTVAPD------AGRYYVQAVNDKNGDNKTSQPITL 201
F G+K+ +S IT+ENT V + AG+Y VQ N + L
Sbjct: 24358 FH-GQKLLQNSE-NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG-----TVDAIL 24410
Query: 202 TVENVGGPADPIAPTIIIPP-KNTSVVA-------GTSEVTLECVANARPLIKLHIIWKK 253
VE P P P +I KN++V++ G S +T V K W+
Sbjct: 24411 DVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEA--KEGAEWQ- 24467
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE 313
L+S IS R+ N T +AGYY + + + + + + +++ P ++
Sbjct: 24468 ---LVSSAISVTTCRIV--NLT-ENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP--FEK 24519
Query: 314 PERHITAEMEKVVDIPCQAKGVPPPSI------TWYKDAAVVEVEKLTRF--RQRNDGGL 365
P + V C PP S +Y + + K + +
Sbjct: 24520 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 24579
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLA-------VTSIAPNITRGPLDSTVIDGMS 418
+ L+ F+ N GE + S V AP+ + V +
Sbjct: 24580 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 24639
Query: 419 VVLACETSGAPRPAITW-QKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTC 475
L C+ +G P+P + W ++G+ I+A G R + G L+I+ DA Y
Sbjct: 24640 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY--RIQEFKGGYHQLIIASVTDDDATVYQV 24697
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSV-----IKGTQASMVCGVTHDPRVTIRYI 530
ATN G +A L V +I P + + ++G S+ + P I
Sbjct: 24698 RATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVIT-- 24755
Query: 531 WEKDGATLGTESHPRIRLDRNGSLHI--SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
W+K + H ++ + R+ + + + D G Y + G D ++ L V
Sbjct: 24756 WQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVAD 24815
Query: 589 LPHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKA 647
+P P +S V R ++NLTWT+P DG S + YI+E A + + +
Sbjct: 24816 VPDPPRG--VKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RE 24871
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 692
T TV L SYQFR+ A N G + S+ +E E+ A
Sbjct: 24872 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 24916
Score = 90.5 bits (223), Expect = 2e-17
Identities = 155/724 (21%), Positives = 278/724 (38%), Gaps = 106/724 (14%)
Query: 311 VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG---GLQI 367
+++ + +T ++ + + CQ G P P I WY+ E+ + +++ +DG L +
Sbjct: 24230 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGK--ELIQSRKYKMSSDGRTHTLTV 24287
Query: 368 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS- 426
+D G++ C A N GEV+TS+ L + + PL + L
Sbjct: 24288 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24347
Query: 427 -GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE 485
G P PA+TW G+++L + T + ++ + + AG Y +N G +
Sbjct: 24348 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVD 24407
Query: 486 ASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTI-RYIWEKDGATLGTESH 543
A D+ + + + T P ++++K + D I Y+ EK A G E
Sbjct: 24408 AILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE-- 24465
Query: 544 PRIRLDRNGSLHISQTWSGDIGTYTCRV------------ISAGGNDSRSAHLRVRQL-- 589
Q S I TCR+ +SA S L V +
Sbjct: 24466 -------------WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 24512
Query: 590 -------PHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
P AP P T++ V + + + W P DG + + Y LE E + +
Sbjct: 24513 IKSPFEKPGAPGKP--TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVT 24570
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP------Q 695
+ + + T +VK L+ Y+FR+ N G+ ++S+ +E ++ + P P +
Sbjct: 24571 TEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELR 24630
Query: 696 NVIASGRTNQSIMIQWQPPPESHQNGILKGYI---------IRYCLAGLPVGYQ---FKN 743
N+ ++N +++ + H I+K Y ++Y + GY +
Sbjct: 24631 NLNVRYQSNATLVCK----VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIAS 24686
Query: 744 ITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEAT 803
+TD D + TN V+ S + V + TL+G+ G VHA
Sbjct: 24687 VTDDDATVYQVRA----TNQGGSVSGTASLEVEVPAKIHLPKTLEGM-----GAVHALRG 24737
Query: 804 NSTTIRFTWNA-PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS--- 859
+I+ ++ P P +I W+ Q+ ++ ++Q + F S
Sbjct: 24738 EVVSIKIPFSGKPDP-----------VITWQKGQD----LIDNNGHYQVIVTRSFTSLVF 24782
Query: 860 --GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
G+++ F V+C + T +L DVP P + S++ S+ ++W E
Sbjct: 24783 PNGVERKDAGF-YVVCAKNRFGIDQKTVEL--DVADVPDPPRGVKVSDVSRDSVNLTWTE 24839
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P G +T Y + E+ T R Y V L T+Y V A G
Sbjct: 24840 PASDGGSKITNYIV--EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGL 24897
Query: 977 GQVS 980
+ S
Sbjct: 24898 SKPS 24901
Score = 83.6 bits (205), Expect = 2e-15
Identities = 113/486 (23%), Positives = 191/486 (39%), Gaps = 71/486 (14%)
Query: 120 KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAP 176
K +V+ GE A S+ V W+ G+K+ PS ++ E +TL +
Sbjct: 5898 KDVTVTAGETATFDCE--LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 5955
Query: 177 DAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
DAG + A + K N L V+ P P V + LE
Sbjct: 5956 DAGEVQLTAKDFKTHAN-------LFVKE--------PPVEFTKPLEDQTVEEGATAVLE 6000
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-----ISDHN-RRLTIPNPTGSDAGYYECEAVLRS 290
C + + W K+G + ++D R+L I + T D Y C+A
Sbjct: 6001 CEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK 6057
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVE 350
+S L+V+ P P + +++ C+ + W+KD A E
Sbjct: 6058 TS-------CNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVKWFKDGA--E 6107
Query: 351 VEKLTRFRQRNDGGLQI---SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRG 407
++K ++ + G ++I + + DD + C R A +TS L V T+
Sbjct: 6108 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLEEEAVFTKN 6163
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKG-ERILASGSVQLPRFTPLESGSLLISPTH 466
+ V + ++ L CE S P + W KG E I+ +G ++ T L+I H
Sbjct: 6164 LANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEI--LTEGRKRILVIQNAH 6220
Query: 467 ISDAGTYTCLATNSR-----GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
+ DAG Y C +SR V E +A+ + PQ+ +++G +A VC ++
Sbjct: 6221 LEDAGNYNCRLPSSRTDGKVKVHELAAEFI--------SKPQNLEILEGEKAEFVCSISK 6272
Query: 522 DPRVTIRYIWEKDGATLGT-ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
+ + W++D TL + + + I + L + D+GTY V G
Sbjct: 6273 E---SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARA 6325
Query: 581 SAHLRV 586
+AHL V
Sbjct: 6326 AAHLTV 6331
Score = 77.4 bits (189), Expect = 1e-13
Identities = 101/443 (22%), Positives = 159/443 (35%), Gaps = 77/443 (17%)
Query: 118 GEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTV 174
G K+ +V GE+ + I+ +P P VTW+R+ +I S IT ++ L+I
Sbjct: 902 GLKNVTVIEGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAF 960
Query: 175 APDAGRYYVQAVNDKNGDNKT-------------------------------SQPITLT- 202
A D+GR+ AVN+ + + S+ + +T
Sbjct: 961 AEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1020
Query: 203 ---VENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
E GP +P AP I P +V G S V C P K H+ WKK GV L+
Sbjct: 1021 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS-VVFGCQVGGNP--KPHVYWKKSGVPLT 1077
Query: 260 GGIS---DHNR-----RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQF- 310
G +N+ +L I DAG Y V+R+ + A S+LE +
Sbjct: 1078 TGYRYKVSYNKQTGECKLVISMTFADDAGEY--TIVVRNKHGET---SASASLLEEADYE 1132
Query: 311 -VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISG 369
+ + ++ + + + + G P + + E E+ ++ + +
Sbjct: 1133 LLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRT 1192
Query: 370 LVPDDTGMFQCFARNAAGEVQ---------------TSTYLAVTSIAPNITRGPLDS--- 411
V D F E++ +AV DS
Sbjct: 1193 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1252
Query: 412 --TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
+++GM V C+ SG P P I W K + + G F SL I D
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 470 AGTYTCLATNSRGVDEASADLVV 492
G YT A+N +G S L V
Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYV 1335
Score = 77.0 bits (188), Expect = 2e-13
Identities = 71/269 (26%), Positives = 105/269 (39%), Gaps = 58/269 (21%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-- 364
PP V + E E V + C G P P++TWY++ ++E F+ G
Sbjct: 896 PPTLVSGLKNVTVIEGESVT-LECHISGYPSPTVTWYRED--YQIESSIDFQITFQSGIA 952
Query: 365 -LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-------------------------- 397
L I +D+G F C A N AG V TS YLAV
Sbjct: 953 RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1012
Query: 398 --------TSI-----------APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKG 438
TS+ AP P+ +++G SVV C+ G P+P + W+K
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072
Query: 439 ERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWART 496
L +G + ++G L+IS T DAG YT + N G ASA L+ A
Sbjct: 1073 GVPLTTGYRYKVSYNK-QTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Query: 497 RITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ Q + + + + V +P+V
Sbjct: 1132 ELLMKSQQEMLYQ----TQVTAFVQEPKV 1156
Score = 69.3 bits (168), Expect = 4e-11
Identities = 134/549 (24%), Positives = 214/549 (38%), Gaps = 78/549 (14%)
Query: 897 PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS-WEEYNRTNTRVTHYLPNVTLEYR 954
P G + +L S +SW+ P + G +T Y + E ++ +VT R
Sbjct: 24421 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTT-CR 24479
Query: 955 VTGLTALTTYTIEVAAMTSKGQG---QVSASTISSGVPPELPGPPTNLGISNIGPRSVTL 1011
+ LT Y V+A + G +VS+ I P E PG P I+ + S +
Sbjct: 24480 IVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS-PFEKPGAPGKPTITAVTKDSCVV 24538
Query: 1012 QFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
++P DG I + +E + + +W+ + + E V +L Y FR
Sbjct: 24539 AWKPPASDGGAKIRNYYLEKREK---KQNKWISV--TTEEIRETVFSVKNLIEGLEYEFR 24593
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAP------ANVSLRTASETSLWLRWM--PLPE 1122
++ N+ G S S+ S I P AP N+++R S +L + P P
Sbjct: 24594 VKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 24653
Query: 1123 ME-YNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAI 1181
++ Y E + +KY + G ++ + D T+ QV+A N
Sbjct: 24654 VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATV----------YQVRATNQG 24703
Query: 1182 GS--GPWSQTVVGRTRESVPSS--GPTNVSALATTSSSMLVRWSEVPEA----------- 1226
GS G S V + +P + G V AL S+ + +S P+
Sbjct: 24704 GSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLI 24763
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
D NG Y+V+ + LV N + G YV V A R G
Sbjct: 24764 DNNG---HYQVIVTRSFTS------LVFPNG---VERKDAGFYV-----VCAKNRFGIDQ 24806
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+ +E + DVP PP G+ +V SV L W PA+ G +IT+ + A
Sbjct: 24807 KT----VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG----SKITNYIVEKCAT 24858
Query: 1347 TATVEVLAPSARQ--YTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPS 1404
TA + AR+ YT L ++ Y FR+ A+ + G + +E T K D+ +
Sbjct: 24859 TAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK----T 24914
Query: 1405 RPMVQQEDV 1413
R M E+V
Sbjct: 24915 RAMNYDEEV 24923
Score = 67.8 bits (164), Expect = 1e-10
Identities = 85/414 (20%), Positives = 173/414 (41%), Gaps = 46/414 (11%)
Query: 16 RAARAQDDVSPYFKTEPVRTQVHL-EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY 74
+ ++A ++V + + + TQ+ + EG RLVL G+ + KW+ N ELT S EY
Sbjct: 26722 KTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA--TDVKWVLNGVELTN-SEEY 26778
Query: 75 RYMITSLDRT---------HAGFYRCIVRNRMGALLQRQTEV----QVAYMGSFEEGEKH 121
RY ++ D+T G CI + + G +++ Q ++ +++ +F +
Sbjct: 26779 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEG-IVKCQYDLTLSKELSDAPAFISQPRS 26837
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDA 178
Q+++ G+ + I+ P P++ WF++ I SS ++I+ +L I + D+
Sbjct: 26838 QNINEGQNVLFTC-EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 26896
Query: 179 GRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECV 238
G+Y ++A N + + T+ + L + +P ++ +TS+ S +++
Sbjct: 26897 GKYTIKAKNFRGQCSATASLMVLPLVE-----EPSREVVLRTSGDTSLQGSFSSQSVQMS 26951
Query: 239 ANARPL-------IKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSS 291
A+ + + + +S + + + S G + S+
Sbjct: 26952 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESST 27011
Query: 292 S--VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S + + +RG PP+ P I+ + KV+ + C G P P +TW +
Sbjct: 27012 SKMLKAGIRGI------PPKIEALPS-DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 27064
Query: 350 EVEKLTRFRQRNDGGLQ---ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI 400
++ RF N L I + D G++ N G + + + SI
Sbjct: 27065 HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118
Score = 65.9 bits (159), Expect = 4e-10
Identities = 107/426 (25%), Positives = 171/426 (40%), Gaps = 45/426 (10%)
Query: 283 ECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEP-ERHITAEMEKVVDIPCQA--KGVPPPS 339
E EA + S P+ + LS+ +P P + H+T K + I + K P
Sbjct: 7956 ENEAGVGHPSEPTEI----LSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 8011
Query: 340 ITWYKDAAVVEVEKLTRFRQRNDGGLQIS---GLVPDDTGMFQCFARNAAG-----EVQT 391
I ++ + V EK R R L+ G+VPD + + A NA G E+
Sbjct: 8012 IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 8071
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLP 450
+ P I D VI+G + + P P ++W K G+ + AS + +
Sbjct: 8072 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 8131
Query: 451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKG 510
S L + + +DAG YT N G AS ++ V + P +D
Sbjct: 8132 N--DHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIG---LPGPCKDIKASDI 8186
Query: 511 TQASMVCGVTHDP------RVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDI 564
T++S C +T +P + Y+ E+ A G ++ + +G +S T I
Sbjct: 8187 TKSS--CKLTWEPPEFDGGTPILHYVLERREA--GRRTYIPVM---SGENKLSWTVKDLI 8239
Query: 565 --GTYTCRVISA----GGNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
G Y RV + GG + + Q P P P + A+ +TW P
Sbjct: 8240 PNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPL 8299
Query: 616 FDGNSPLIRYILE-MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S ++ YI+E +++ W + P T T KGL + YQFR+ A N G
Sbjct: 8300 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILT-YTAKGLEEGKEYQFRVRAENAAGIS 8358
Query: 675 QFSKDT 680
+ S+ T
Sbjct: 8359 EPSRAT 8364
Score = 65.9 bits (159), Expect = 4e-10
Identities = 75/363 (20%), Positives = 146/363 (40%), Gaps = 33/363 (9%)
Query: 251 WKKDGVLLSG------GISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSV 304
W +GV L+ G+S ++ LTI + D G C S + +V+ Y
Sbjct: 26765 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI----SKTKEGIVKCQYDLT 26820
Query: 305 L-----EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFR 358
L + P F+ +P E + V+ C+ G P P I W+K+ + + ++ R
Sbjct: 26821 LSKELSDAPAFISQPRSQNINEGQNVL-FTCEISGEPSPEIEWFKNNLPISISSNVSISR 26879
Query: 359 QRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL----DSTVI 414
RN L+I D+G + A+N G+ + L V + +R + T +
Sbjct: 26880 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 26939
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
G + + S + + A ++ AS ++ +F + + S+ + + +
Sbjct: 26940 QGSFSSQSVQMSASKQEA-SFSSFSSSSASSMTEM-KFASMSAQSMSSMQESFVEMSSSS 26997
Query: 475 CLATNSRGVDEASADLVVWARTRITKP-----PQDQSVIKGTQASMVCGVTHDPRVTIRY 529
+ ++ E+S ++ A R P P D S+ +G ++ C T +P T
Sbjct: 26998 FMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEP--TPEV 27055
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W G + ++ R ++ +L I D G YT + + G+DS + ++ +
Sbjct: 27056 TWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Query: 587 RQL 589
R +
Sbjct: 27116 RSI 27118
Score = 64.7 bits (156), Expect = 9e-10
Identities = 118/468 (25%), Positives = 185/468 (39%), Gaps = 61/468 (13%)
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN----TLVILSTVAPD 177
Q+V G A R R+ P P+ W+++G KI S RI LVI A D
Sbjct: 2041 QTVGQGSDAHFRV-RVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAED 2099
Query: 178 AGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSE--VTL 235
+ V+A+N +TS L V+ I + VVA + T
Sbjct: 2100 SASIMVKAINIA---GETSSHAFLLVQ--------AKQLITFTQELQDVVAKEKDTMATF 2148
Query: 236 ECVANARPLIKLHIIWKKDGVLLSGG--ISDHNRR----LTIPNPTGSDAGYYECEAVLR 289
EC + P +K + W KDG+ + G H+ R L+I SDA Y C V
Sbjct: 2149 EC-ETSEPFVK--VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2205
Query: 290 ---SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY-KD 345
++ +V GA + ++ Q ++ PE + + E+E +V P +G WY D
Sbjct: 2206 ENVKTTAKLIVEGAVVEFVKELQDIEVPESY-SGELECIVS-PENIEG------KWYHND 2257
Query: 346 AAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ K T +R L + + +D G + +T+ L + I
Sbjct: 2258 VELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKLKMKPRPIAIL 2313
Query: 406 RGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
+G D V +G V L + S + + G+ + S V + +S LLI
Sbjct: 2314 QGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI--VIDKQSHMLLIEDM 2371
Query: 466 HISDAGTYTC------LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGV 519
DAG Y+ L+T+ R V S D++ P +D +VI+GT+A + C V
Sbjct: 2372 TKEDAGNYSFTIPALGLSTSGR-VSVYSVDVIT--------PLKDVNVIEGTKAVLECKV 2422
Query: 520 THDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
+ P VT + D + I L I++T + D G Y
Sbjct: 2423 S-VPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2469
Score = 64.3 bits (155), Expect = 1e-09
Identities = 86/335 (25%), Positives = 128/335 (38%), Gaps = 34/335 (10%)
Query: 268 RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVD 327
RL IP+ SDAG Y A S+ V G + + + +K+ E + + VV+
Sbjct: 3067 RLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRI----RSIKK-EVQVIEKQRAVVE 3121
Query: 328 IPCQAKGVPPPSITWYKDAAVVEVEKLTRFR---QRNDGGLQISGLVPDDTGMFQCFARN 384
V WYKD + + R + +R + IS D G +
Sbjct: 3122 FEVNEDDV---DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF---- 3174
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLACETSGAPRPAITWQKGERILA 443
AG ++S L V + P L TV G SG P+P I+W K E++L+
Sbjct: 3175 VAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLS 3234
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA--------- 494
+G + + +LL+ DA YTC A N GV SA L V
Sbjct: 3235 TG-FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Query: 495 ----RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW-EKDGATLGTESHPRIRLD 549
I P QD +G A C V+ ++ W KD + + +
Sbjct: 3294 MPVYPPAIITPLQDTVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
L I++ + D GTYT +A G S +A+L
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 64.3 bits (155), Expect = 1e-09
Identities = 103/471 (21%), Positives = 164/471 (34%), Gaps = 106/471 (22%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQ 197
P P VTW R G+ + S+R +T ++T I S A D G Y V +N + K
Sbjct: 26283 PVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVV---ENSEGKQEA 26339
Query: 198 PITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVL 257
TLT++ A + PP+ V + P +K K
Sbjct: 26340 EFTLTIQK----ARVTEKAVTSPPR---------------VKSPEPRVKSPEAVKSP--- 26377
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA-YLSVLEPPQFVKEPER 316
+R+ P P+ +AV + + P+ +L V PP+ + +
Sbjct: 26378 ---------KRVKSPEPSHP-------KAVSPTETKPTPTEKVQHLPVSAPPKITQFLKA 26421
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQISGLVPDD 374
+ E+ K+ + ++ + +TWYKD ++ +F DG L+I+ L D
Sbjct: 26422 EASKEIAKLTCV-VESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESD 26480
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G + CE SG
Sbjct: 26481 QGEY-------------------------------------------VCEISG------- 26490
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 494
+G + F + IS T SD T T E A + +
Sbjct: 26491 --EGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT---EPKAPEPISS 26545
Query: 495 RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS- 553
+ I QD +V + A T +PR T IW KDG + ++ D+ G
Sbjct: 26546 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTA--IWTKDGKAITQGGKYKLSEDKGGFF 26603
Query: 554 LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVE 604
L I +T + D G YTC V ++ G+ S S L ++ + V+T T E
Sbjct: 26604 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 26654
Score = 63.9 bits (154), Expect = 2e-09
Identities = 140/627 (22%), Positives = 231/627 (36%), Gaps = 83/627 (13%)
Query: 17 AARAQDDVSPYFKTEPVRTQVH------LEGNRLVLTCMAEGSWP-LEFKWLHNNRELT- 68
A +A + Y + + + H LE R + C E S P + +W+ +++EL
Sbjct: 2996 AGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFEC--EVSEPDITVQWMKDDQELQI 3053
Query: 69 -------KFSLEYRYMITSLDRTHAGFYRCIVRNRMGA--LLQRQTEVQVAYMGSFEEGE 119
K +R +I S + AG Y + + L +V++ + +
Sbjct: 3054 TDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSI------K 3107
Query: 120 KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKI--PPSSRIAITLE---NTLVILSTV 174
K V + AV+ + W++DG +I R +E + + I T
Sbjct: 3108 KEVQVIEKQRAVVEFE--VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3165
Query: 175 APDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVT 234
DAG Y A G N++S +TL V P P ++ + +V +G
Sbjct: 3166 QSDAGEYTFVA-----GRNRSS--VTLYVNA------PEPPQVLQELQPVTVQSG-KPAR 3211
Query: 235 LECVANARPLIKLHIIWKKDGVLLSGGIS------DHNRRLTIPNPTGSDAGYYECEA-- 286
V + RP K I W K+ LLS G L + DA Y CEA
Sbjct: 3212 FCAVISGRPQPK--ISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKN 3269
Query: 287 --------VLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPP 338
S VP VV + PP + + +T+E + C+ G
Sbjct: 3270 DYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPA-RFQCRVSGTDL- 3327
Query: 339 SITWYKDAAVVEVEKLTRFRQRNDG-GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
++WY ++ + R Q D L+I+ P+D G + A NA G+V ++ L++
Sbjct: 3328 KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Query: 398 TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLES 457
A + R V + ++S + QK + S + ES
Sbjct: 3388 EVQA--LDRQSSGKDVRESAKSQAVADSSFTKEESKISQKEIKSFQGSSYEY-EVQVFES 3444
Query: 458 GSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPP------QDQSVIKGT 511
S T S T C + + E++ A+ + P QD +V G
Sbjct: 3445 VSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGD 3504
Query: 512 QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS---LHISQTWSGDIGTYT 568
A +C + D + + W +GA + E R++ +NG+ L I D G Y+
Sbjct: 3505 TAQFLCVLKDDSFIDV--TWTHEGAKI--EESERLKQSQNGNIQFLTICNVQLVDQGLYS 3560
Query: 569 CRVISAGGNDSRSAHLRVRQLPHAPEH 595
C V + G + SA L V P + H
Sbjct: 3561 CIVHNDCGERTTSAVLSVEGAPESILH 3587
Score = 62.4 bits (150), Expect = 5e-09
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 8/165 (4%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQ 390
G P P ++W++D V+ L + G L I + ++G + A N +G+
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQAT 90
Query: 391 TSTYLAVTS--IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSV 447
++ L V + PN + TV G V L +G P P + + + G I +S
Sbjct: 91 STAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDF 150
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
Q+ + L S LLI+ + D+GTY+ ATNS G ++A+L+V
Sbjct: 151 QISQEGDLYS--LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 62.0 bits (149), Expect = 6e-09
Identities = 51/212 (24%), Positives = 104/212 (49%), Gaps = 13/212 (6%)
Query: 397 VTSIAPNITRGPLDSTVI-DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPL 455
+T+ AP T+ PL S V+ +G + SG P P ++W + +++++ ++ + +
Sbjct: 1 MTTQAPTFTQ-PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS 59
Query: 456 ESGSLLISPTHI-SDAGTYTCLATNSRGVDEASADLVVWART---RITKPPQDQSVIKGT 511
+ + L P +++G Y+ ATN G ++A+L+V A T + Q +V +G+
Sbjct: 60 DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGS 119
Query: 512 QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH---ISQTWSGDIGTYT 568
Q + VT P +++ +DGA + +S ++ + G L+ I++ + D GTY+
Sbjct: 120 QVRLQVRVTGIPTPVVKFY--RDGAEI--QSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 569 CRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
++ G + +A L V+ P T+
Sbjct: 176 VNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Score = 62.0 bits (149), Expect = 6e-09
Identities = 50/193 (25%), Positives = 85/193 (44%), Gaps = 13/193 (6%)
Query: 214 APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG--------ISDH 265
APT P ++ V+ G S T E + P+ + + W +DG ++S SD
Sbjct: 5 APTFTQPLQSVVVLEG-STATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDG 61
Query: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
+LTIP T +++G Y +A S S + PP FV+ + +T
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-SMTVRQGSQ 120
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARN 384
V + + G+P P + +Y+D A ++ + Q D L I+ P+D+G + A N
Sbjct: 121 VRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 385 AAGEVQTSTYLAV 397
+ G ++ L V
Sbjct: 181 SVGRATSTAELLV 193
Score = 61.6 bits (148), Expect = 8e-09
Identities = 73/294 (24%), Positives = 108/294 (36%), Gaps = 64/294 (21%)
Query: 343 YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA- 401
YK A VEV+K + G+ I+G + F+ A +T+ A I
Sbjct: 844 YKSEAGVEVKK--------EVGVSITGTTVREE-RFEVLHGREAKVTETARVPAPVEIPV 894
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P + G + TVI+G SV L C SG P P +TW + + + S S+
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIES-SIDFQITFQSGIAR 953
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADL----------------------------- 490
L+I D+G +TC A N G S L
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013
Query: 491 --VVWARTRITK---------------PPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
VV T +T+ P Q +++G C V +P+ + W+K
Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV--YWKK 1071
Query: 534 DGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
G L T ++ ++ L IS T++ D G YT V + G S SA L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 58.9 bits (141), Expect = 5e-08
Identities = 73/277 (26%), Positives = 111/277 (40%), Gaps = 21/277 (7%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSI--TWYKDAAVVEVEKLTRF-RQRNDG 363
P +FVKE + I E E V V P + TW KD + + RF D
Sbjct: 4809 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 4868
Query: 364 GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLA 422
L I + D G + C R E ++ L V + + + TV+ G + L+
Sbjct: 4869 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLS 4928
Query: 423 CETSGAPRPAITWQKGERILASGSVQLP-RFTPLESG---SLLISPTHISDAGTYTCLAT 478
CE + + W+K +I+ V+ P R P G +L I+ +DAGTYT
Sbjct: 4929 CELN--KERDVVWRKDGKIV----VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 4982
Query: 479 NSRGVDEASADLVVWA-RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
N+ ++ +S VV R + KP +DQ V A C + D T W K
Sbjct: 4983 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKD---TPNIKWFKGYDE 5039
Query: 538 LGTESHPRIRLDRNGS---LHISQTWSGDIGTYTCRV 571
+ E + + + R+G+ L I DI Y +
Sbjct: 5040 IPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 5076
Score = 58.5 bits (140), Expect = 7e-08
Identities = 119/615 (19%), Positives = 209/615 (33%), Gaps = 95/615 (15%)
Query: 22 DDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSL 81
+ +PYF T+PV Q +EG +V C G+ W + LT YRY ++
Sbjct: 1032 EPAAPYFITKPV-VQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTT---GYRYKVSYN 1087
Query: 82 DRT-------------HAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGE 128
+T AG Y +VRN+ G + ++ A + ++
Sbjct: 1088 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQV 1147
Query: 129 AAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVND 188
A ++ P++ V + + I + V++ T D +++ + +
Sbjct: 1148 TAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQ-EFHISSFEE 1206
Query: 189 KNGDNKTSQPITLTVENVG------------GPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
+ + I T+E + ++ + KN ++ G VT
Sbjct: 1207 RLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMG-VTFH 1265
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-------ISDHNRRLTIPNPTGSDAGYYECEAVLR 289
C + PL K I W KDG + G + D L IP D G Y A
Sbjct: 1266 CKMSGYPLPK--IAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA--- 1320
Query: 290 SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S ++G + C K P+ +
Sbjct: 1321 -----SNIKGNAI---------------------------CSGKLYVEPAAPLGAPTYIP 1348
Query: 350 EVEKLTRFRQRNDGGLQISGLVPDDTGMFQCF---ARNAAGEVQTSTYLAVTSIA----- 401
+E ++R R + + S + M AR + + L T +
Sbjct: 1349 TLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERL 1408
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P P+ ++G + + G P P W + + + + S
Sbjct: 1409 YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQS 1468
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQAS 514
L+I P SD+G +T +A N G S L V A KP ++ ++ +G++
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1528
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD---RNGSLHISQTWSGDIGTYTCRV 571
M T +P I +W K+ + +P+IR++ +L I T S D YT
Sbjct: 1529 MKVRATGNPNPDI--VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1586
Query: 572 ISAGGNDSRSAHLRV 586
I+ G D+ + V
Sbjct: 1587 INKAGRDTTRCKVNV 1601
Score = 58.5 bits (140), Expect = 7e-08
Identities = 63/252 (25%), Positives = 95/252 (37%), Gaps = 21/252 (8%)
Query: 262 ISDHNRRLTIPNPTGSDAGYYEC---------EAVLRSSSVPSVVRGAYLSVLEPPQFVK 312
+ D R + N G D+ Y E + R + R + +LE P
Sbjct: 25329 LDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFT 25388
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRNDGGLQ---IS 368
P + TA + + V P P +TWYK ++ + ++ +D GL I+
Sbjct: 25389 LPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTIN 25448
Query: 369 GLVPDDTGMFQCFARNAAGEVQTSTYLAVT--------SIAPNITRGPLDSTVIDGMSVV 420
+ DD + ARN GE L VT ++ P R ++ +G SV
Sbjct: 25449 SVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVC 25508
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
SG P P + W+K + L+ G L+ +L I T D G Y ATN+
Sbjct: 25509 FEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT 25568
Query: 481 RGVDEASADLVV 492
G A L V
Sbjct: 25569 AGSTSCQAHLQV 25580
Score = 57.8 bits (138), Expect = 1e-07
Identities = 84/361 (23%), Positives = 124/361 (34%), Gaps = 62/361 (17%)
Query: 279 AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPP 338
A C +RS SV + S+ P V H E V C+ +
Sbjct: 25235 AARISCGGAIRSQKGVSVAKVKVASIEIGP--VSGQIMHAVGEEGGHVKYVCKIENYDQS 25292
Query: 339 S-ITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTY 394
+ +TWY V ++E ++ + G L + + D G ++C N GE +
Sbjct: 25293 TQVTWY--FGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAE 25350
Query: 395 LAVTSIA---------------------------PNITRGPLDSTVIDGMSVVLACETSG 427
L V + P T + T G +V +
Sbjct: 25351 LFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITV 25410
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDE 485
P P +TW K + + G + G L I+ D YT +A N G D
Sbjct: 25411 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS 25470
Query: 486 ASADLVVWARTRITKPPQDQSV---IKGTQASMVCG----------VTHDPRVTIRYIWE 532
A L V + PP D ++ K A+ C V+ P T++ WE
Sbjct: 25471 CKAKLTV----TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WE 25524
Query: 533 KDGATLGTESHPRIRLDRNG----SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
KDG L P I + G +LHI T D G Y + G+ S AHL+V +
Sbjct: 25525 KDGQPLSLG--PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVER 25582
Query: 589 L 589
L
Sbjct: 25583 L 25583
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Query: 388 EVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSV 447
E +++T T++A I P TV +G S +C+T G P P +TW + ++L++ +
Sbjct: 26242 EEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSAR 26301
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW----ARTRITKPPQ 503
T +S + IS SD G Y+ + NS G EA L + +T PP+
Sbjct: 26302 HQVTTTKYKS-TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPR 26360
Query: 504 DQS 506
+S
Sbjct: 26361 VKS 26363
Score = 57.4 bits (137), Expect = 2e-07
Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 26/210 (12%)
Query: 308 PQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFR-QRNDGGLQ 366
P F+KE + M V + G+P P I W+ + ++ +F +D L
Sbjct: 3649 PIFIKEVS-NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLI 3707
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS-------------IAPNITR--GPLDS 411
I +D G + C A N G+ S YL + S +A ++ + GP
Sbjct: 3708 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3767
Query: 412 TVI---------DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLI 462
+ G+ + G P P +TW K + L + P SG+ ++
Sbjct: 3768 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 3827
Query: 463 SPTHISDAGTYTCLATNSRGVDEASADLVV 492
+ D+G Y C A N G +A+L+V
Sbjct: 3828 NDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 55.8 bits (133), Expect = 4e-07
Identities = 90/391 (23%), Positives = 145/391 (37%), Gaps = 54/391 (13%)
Query: 56 LEFKWLHNN--RELTKF--SLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY 111
L+ WL R TK +L++R +L + R G ++ Q V VA
Sbjct: 25195 LQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAK 25254
Query: 112 M--GSFEEGEKHQSVSH--GEAA--VIRAPRIASFPQP-QVTWFRDGRKIPPSSRIAITL 164
+ S E G + H GE V +I ++ Q QVTW+ R++ S + IT
Sbjct: 25255 VKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25314
Query: 165 ENTLVIL---STVAPDAGRYYVQAVNDKNGDNKTSQPIT------------LTVENVGGP 209
E+ + IL D G Y + VND D+ ++ T++ +
Sbjct: 25315 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25374
Query: 210 ADPI-----APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISD 264
D + P +P N + G V P + H+ W K G + G +D
Sbjct: 25375 TDTMRLLERPPEFTLPLYNKTAYVG-ENVRFGVTITVHP--EPHVTWYKSGQKIKPGDND 25431
Query: 265 HN---------RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP---QFVK 312
+LTI + T D Y V R+ + L PP ++
Sbjct: 25432 KKYTFESDKGLYQLTINSVTTDDDAEY--TVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25489
Query: 313 EPERHITAEME----KVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRND-GGLQ 366
+ + A E + V + G+PPP++ W KD + + + + D L
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
I +P+DTG ++ A N AG +L V
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25580
Score = 55.5 bits (132), Expect = 6e-07
Identities = 62/224 (27%), Positives = 93/224 (41%), Gaps = 25/224 (11%)
Query: 1721 QAAPSAPSS-VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVS-KIVTVD 1777
Q P P+ + L S +SW+ P G + Y V E C +G ++V+
Sbjct: 24415 QDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNY--VVEKCEAKEGAEWQLVSSA 24472
Query: 1778 VKGNSPLWLKVKDLAEGVTYRFRIRAK-TFTYGPEIEAN---VTTGPGE--GAPGPPGVP 1831
+ S ++ +L E Y FR+ A+ TF +E + + P E GAPG P +
Sbjct: 24473 I---SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24529
Query: 1832 IIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILK 1891
+ + S +A + D G I Y +E R + W I +E+ FS+ L
Sbjct: 24530 AVTKDSCVVAWKPPASDGG-AKIRNYYLEKREKKQNKW---ISVTTEEIRETVFSVKNLI 24585
Query: 1892 PGVSYDFRVIAVNDYG------FGTPSSPSQSVPAQKANPFYEE 1929
G+ Y+FRV N G P +P VP Q A F EE
Sbjct: 24586 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ-APHFKEE 24628
Score = 55.1 bits (131), Expect = 7e-07
Identities = 128/600 (21%), Positives = 208/600 (34%), Gaps = 102/600 (17%)
Query: 23 DVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---KFSLEYRYM-- 77
+ PYF T + + +E + + L C P+ KW + E+ K+S++ +
Sbjct: 5355 EADPYF-TVKLHDKTAVEKDEITLKCEVSKDVPV--KWFKDGEEIVPSPKYSIKADGLRR 5411
Query: 78 ---ITSLDRTHAGFYRCIV---RNRMGALLQRQ----------TEVQVAYMGSFEEGEKH 121
I D G Y C + + ++ + EV V FE
Sbjct: 5412 ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSE 5471
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY 181
V HG+ + P AS P DG+K + L++ + G
Sbjct: 5472 PDV-HGQWKLKGQPLTAS---PDCEIIEDGKK------------HILILHNCQLGMTGEV 5515
Query: 182 YVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANA 241
QA N K+ N L V+ + P I I P + V E EC +
Sbjct: 5516 SFQAANAKSAAN-------LKVKEL--------PLIFITPLSDVKVFEKDEAKFECEVSR 5560
Query: 242 RPLIKLHIIWKKDGVLLSGG-----ISDHNRR-LTIPNPTGSDAGYYECEAVLRSSSVPS 295
P W K ++G I D + + I + D Y EA + +S
Sbjct: 5561 EPKT---FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKL 5617
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKL 354
++ G L L P + V E+ V + + + W+K D + +
Sbjct: 5618 IIEGIRLKFLTPLKDVTAKEKE-----SAVFTVELSHDNI---RVKWFKNDQRLHTTRSV 5669
Query: 355 TRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI 414
+ + + L DDT + A + E + L V P T D T +
Sbjct: 5670 SMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAK----LTVLEGDPYFTGKLQDYTGV 5725
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
+ V+L CE S A P ++ G+ I S + + + L++ SD G YT
Sbjct: 5726 EKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIK--ADGKKRMLILKKALKSDIGQYT 5783
Query: 475 CLATNSRGVDEASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
C G D+ S L + R ++ +P V++ A ++ D I W+
Sbjct: 5784 C----DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISED---DIHANWKL 5836
Query: 534 DGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG------NDSRSAHLRVR 587
G L P + G +H + + CR+ GG N SAHLRV+
Sbjct: 5837 KGEAL--LQTPDCEIKEEGKIH-------SLVLHNCRLDQTGGVDFQAANVKSSAHLRVK 5887
Score = 54.7 bits (130), Expect = 1e-06
Identities = 91/439 (20%), Positives = 152/439 (34%), Gaps = 53/439 (12%)
Query: 92 IVRNRMGALLQRQTEVQVAY--------MGSFEEGEKHQSVSHGEAAVIRAPRIASFPQP 143
I++ + LL+ E ++A F+ K+ + G +++ +P P
Sbjct: 1216 IIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHC-KMSGYPLP 1274
Query: 144 QVTWFRDGRKIPPSSRIAITL----ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPI 199
++ W++DG++I R + +L I + D G Y A N K + +
Sbjct: 1275 KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK-- 1332
Query: 200 TLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
L VE PA P+ IP TLE V+ R L + + + +S
Sbjct: 1333 -LYVE----PAAPLGAPTYIP-------------TLEPVSRIRSLSPRSV--SRSPIRMS 1372
Query: 260 GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHIT 319
R +P L + + R L P FV +P
Sbjct: 1373 PARMSPARM----SPARMSPARMSPGRRLEETDESQLER------LYKPVFVLKPVSFKC 1422
Query: 320 AEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGLVPDDTGM 377
E + + G P P W+ D + + + + DG L I P D+G
Sbjct: 1423 LEGQ-TARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGE 1481
Query: 378 FQCFARNAAGEVQTSTYLAVTSIA----PNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
+ A+N AG S L V ++ P + + +G + + +G P P I
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 434 TWQKGERILASGSVQLPRFTPLES-GSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
W K I+ R + +L I T D+ YT A N G D + V
Sbjct: 1542 VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Query: 493 WARTRITKPPQDQSVIKGT 511
+P + + +GT
Sbjct: 1602 EVEFAEPEPERKLIIPRGT 1620
Score = 53.5 bits (127), Expect = 2e-06
Identities = 85/398 (21%), Positives = 146/398 (36%), Gaps = 47/398 (11%)
Query: 221 PKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG-----ISDHNRRLTIPNPT 275
P V + ECV + ++IW K ++ I+D + + + N +
Sbjct: 5186 PLKDVTVPERRQARFECVLTR----EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 5241
Query: 276 G-SDAGYYECEAVLRSSSVPSVVRGAYLSVLEP--PQFVKEPERHITAEMEKVVDIPCQA 332
D G Y E + +S V G L + P Q VKE E C+
Sbjct: 5242 QFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGE---------TATFVCEL 5292
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARNAAGEVQT 391
+ W+K+ A + + L++ + DD + + E+ +
Sbjct: 5293 SH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----ELSS 5347
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPR 451
+ L V P T D T ++ + L CE S P ++ GE I+ S P+
Sbjct: 5348 TAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVKWFKDGEEIVPS-----PK 5401
Query: 452 FTPLESG---SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR-TRITKPPQDQSV 507
++ G L I + D G Y C G D+ A++ V AR ++ KP V
Sbjct: 5402 YSIKADGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARLIKVEKPLYGVEV 5457
Query: 508 IKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
G A ++ + W+ G L + P + +G HI + +G
Sbjct: 5458 FVGETAHFEIELSEP---DVHGQWKLKGQPL--TASPDCEIIEDGKKHILILHNCQLG-M 5511
Query: 568 TCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
T V N +A+L+V++LP P++ + E+
Sbjct: 5512 TGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEK 5549
Score = 53.1 bits (126), Expect = 3e-06
Identities = 97/442 (21%), Positives = 163/442 (36%), Gaps = 51/442 (11%)
Query: 145 VTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITL 201
V WF+DG++I PS I + L++ + D G+Y G +KTS + +
Sbjct: 5743 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC-----GTDKTSGKLDI 5797
Query: 202 TVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLL--- 258
+ + P + T +E++ + +H WK G L
Sbjct: 5798 EDREI----KLVRPLHSVEVMETETARFETEISED---------DIHANWKLKGEALLQT 5844
Query: 259 -SGGISDHNR--RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPE 315
I + + L + N G + +A SS V+ + +L P + V
Sbjct: 5845 PDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT--- 5901
Query: 316 RHITAEMEKVVDIPCQAKGVPPPSITWY-KDAAVVEVEKLTRFRQRNDGGLQISGLVPDD 374
+TA D + +P + WY K + +K+ + L + + +D
Sbjct: 5902 --VTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 5956
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G Q A+ + +T L V T+ D TV +G + VL CE S
Sbjct: 5957 AGEVQLTAK----DFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKW 6012
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADL-VVW 493
++ G IL S ++ + L+I D TYTC A + + S +L VV
Sbjct: 6013 FKNGTEILKSKKYEIVADGRVR--KLVIHDCTPEDIKTYTCDAKDFK----TSCNLNVVP 6066
Query: 494 ARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT-ESHPRIRLDRNG 552
+P D V + A C ++ R + W KDGA + + + I
Sbjct: 6067 PHVEFLRPLTDLQVREKEMARFECELS---RENAKVKWFKDGAEIKKGKKYDIISKGAVR 6123
Query: 553 SLHISQTWSGDIGTYTCRVISA 574
L I++ D Y+C V +A
Sbjct: 6124 ILVINKCLLDDEAEYSCEVRTA 6145
Score = 50.8 bits (120), Expect = 1e-05
Identities = 68/294 (23%), Positives = 106/294 (36%), Gaps = 43/294 (14%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTR--FRQRNDGGLQISGLVPDDTGMFQCFAR 383
V C+ G P P I WYKD ++ + + F Q L+I ++P+D G++ FA
Sbjct: 1262 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1321
Query: 384 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 443
N G S L V AP GAP T + RI +
Sbjct: 1322 NIKGNAICSGKLYVEPAAP-----------------------LGAPTYIPTLEPVSRIRS 1358
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP-- 501
+ R +P+ +SP +S A + R ++E + R+ KP
Sbjct: 1359 LSPRSVSR-SPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQL----ERLYKPVF 1413
Query: 502 ---PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG--SLHI 556
P ++G A V P W DG + + ++ + +G SL I
Sbjct: 1414 VLKPVSFKCLEGQTARFDLKVVGRPMP--ETFWFHDGQQIVNDYTHKVVIKEDGTQSLII 1471
Query: 557 SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINL 610
D G +T + G S S L V A EH V + + + +N+
Sbjct: 1472 VPATPSDSGEWTVVAQNRAGRSSISVILTV----EAVEHQVKPMFVEKLKNVNI 1521
Score = 50.4 bits (119), Expect = 2e-05
Identities = 104/471 (22%), Positives = 175/471 (37%), Gaps = 66/471 (14%)
Query: 113 GSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLV 169
G+ + Q+V+ + AV + P + W RDG+ +P ++ I + L+
Sbjct: 2574 GAISKPLTDQTVAESQEAVFECE--VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLI 2631
Query: 170 ILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAG 229
I +T D G Y + K L VE V I T+ KN +V
Sbjct: 2632 IAATKLDDIGEYTYKVATSKTS-------AKLKVEAV-----KIKKTL----KNLTVT-- 2673
Query: 230 TSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLR 289
++ + V P +K + W K+GV+L + N + I S G +
Sbjct: 2674 ETQDAVFTVELTHPNVK-GVQWIKNGVVL-----ESNEKYAI-----SVKGTIYSLRIKN 2722
Query: 290 SSSVPSVVRGAYLSVL--------EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSIT 341
+ V V G L L E + +K+P + +TA V P
Sbjct: 2723 CAIVDESVYGFRLGRLGASARLHVETVKIIKKP-KDVTALENATVAFEVSVSHDTVPVKW 2781
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
++K + +K +R L + + P D G + G+++ L V ++
Sbjct: 2782 FHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTA----VVGQLECKAKLFVETL- 2836
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+IT+ + V + + CE S P++ + G I S ++ L L+
Sbjct: 2837 -HITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLH--QLI 2893
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
I T D+ YT + N D+ SA L V P S++K A +T
Sbjct: 2894 IMNTSTEDSAEYTFVCGN----DQVSATLTV-------TPIMITSMLKDINAEEKDTITF 2942
Query: 522 DPRVT---IRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYT 568
+ V I Y W K+G + + ++R + SL+I GD YT
Sbjct: 2943 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYT 2993
Score = 50.1 bits (118), Expect = 2e-05
Identities = 48/156 (30%), Positives = 63/156 (40%), Gaps = 4/156 (2%)
Query: 340 ITWY-KDAAVVEVEKLTRFRQRNDGGLQISGLVPDD-TGMFQCFARNAAGEVQTSTYLAV 397
+ WY ++ V EK + +N L I + +D G + C A N +G+ TS L V
Sbjct: 4464 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4523
Query: 398 TS-IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLE 456
AP I R V G CE AP W K R + R +
Sbjct: 4524 VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4583
Query: 457 SGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
S SL I T + D G YTC A+N G +A L V
Sbjct: 4584 S-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/350 (24%), Positives = 134/350 (38%), Gaps = 39/350 (11%)
Query: 232 EVTLEC-VANARPLIKLHIIWKKDGVLLSGG------ISDHNRRLTIPNPTGSDAGYYEC 284
EV L+C ++ A +K W KDG + R L + SD G Y C
Sbjct: 5729 EVILQCEISKADAPVK----WFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC 5784
Query: 285 EAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV---DIPCQAKGVPPPSIT 341
+ +S + + ++ P V+ E TA E + DI K
Sbjct: 5785 DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETE-TARFETEISEDDIHANWK-------- 5835
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
K A+++ + L + D TG A N V++S +L V
Sbjct: 5836 -LKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAAN----VKSSAHLRVKPRV 5890
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+ R D TV G + CE S P + KG+++ S V +PR + + +L
Sbjct: 5891 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKV-VPR-SEGKVHTLT 5948
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVV-WARTRITKPPQDQSVIKGTQASMVCGVT 520
+ + DAG A + + A+L V TKP +DQ+V +G A + C V+
Sbjct: 5949 LRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS 6004
Query: 521 HDPRVTIRYIWEKDGA-TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTC 569
R + W K+G L ++ + + R L I DI TYTC
Sbjct: 6005 ---RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 6051
Score = 48.1 bits (113), Expect = 9e-05
Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 1850 GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G +T Y++E R +D W + EV +F + L PG Y FRV AVN+YG G
Sbjct: 12421 GGSQVTHYIVEKREADRKTWST----VTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPG 12476
Query: 1910 TPSSPSQSVPA 1920
P+ + V A
Sbjct: 12477 VPTDVPKPVLA 12487
Score = 47.8 bits (112), Expect = 1e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 1364 GLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW- 1422
G++ + + + A+ R G + L V D P PP V+ DV SV L+W
Sbjct: 24785 GVERKDAGFYVVCAKNRFGIDQKTVELDVA----DVPDPPRG--VKVSDVSRDSVNLTWT 24838
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
EP SDG S + Y ++ + RW + + + V L TSY+FRV A N
Sbjct: 24839 EPASDGGSKITNYIVEKCATTAERWLRVGQA---RETRYTVINLFGKTSYQFRVIAENKF 24895
Query: 1483 GDSEFSEESESLTT 1496
G S+ SE SE T
Sbjct: 24896 GLSKPSEPSEPTIT 24909
Score = 47.0 bits (110), Expect = 2e-04
Identities = 66/318 (20%), Positives = 120/318 (37%), Gaps = 55/318 (17%)
Query: 30 TEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSL----------EYRYMIT 79
T+P+++ V LEG+ G E W + + ++ +L + I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 80 SLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP-RIA 138
++ + ++G Y N G + A ++ QS++ + + +R R+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 139 SFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
P P V ++RDG +I S I+ E +L+I D+G Y V A N T
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATST 188
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVT----------LECVANARPLI 245
++ + E V P K T + T++++ +E +AR +
Sbjct: 189 AELLVQGEEEV-------------PAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIA 235
Query: 246 KLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVL 305
+ ++ DG +G H IP S RS + PS+ A L+
Sbjct: 236 TVEMV--IDGA--AGQQLPHKTPPRIPPKPKS-----------RSPTPPSIAAKAQLARQ 280
Query: 306 EPPQFVK---EPERHITA 320
+ P ++ P RH+ A
Sbjct: 281 QSPSPIRHSPSPVRHVRA 298
Score = 46.2 bits (108), Expect = 3e-04
Identities = 64/304 (21%), Positives = 114/304 (37%), Gaps = 32/304 (10%)
Query: 304 VLEPPQFVKEPERHITAEMEKVVDIPC--------QAKGVPPPSITWYKDAAVVEVEKLT 355
VL F + IT M +PC + P + WY + VE+++ +
Sbjct: 26057 VLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQSKPTAEVKWYHNG--VELQESS 26113
Query: 356 RFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-----TSIAPNITRG 407
+ N G L+I DD+G ++ N GE L V T+ A
Sbjct: 26114 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDE 26173
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHI 467
+ +V ++ A S +++K + AS SV+ + E+ L S H
Sbjct: 26174 EVPRSVFPELTRTEAYAVS-------SFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 26226
Query: 468 SDAGTYTCLATNSRGVDEASA--DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ A + A + ++E S + RI P+ +V +G A C +P
Sbjct: 26227 ASAEMKSA-ALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVP 26285
Query: 526 TIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
T+ W + G L T + ++ + + IS + D G Y+ V ++ G L
Sbjct: 26286 TV--TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 26343
Query: 585 RVRQ 588
+++
Sbjct: 26344 TIQK 26347
Score = 45.4 bits (106), Expect = 6e-04
Identities = 52/240 (21%), Positives = 89/240 (37%), Gaps = 51/240 (21%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITL---ENTLVILSTVAPDAGR 180
+S G+ A + + P+P++ WF +G + PS+ +++L+IL T D G
Sbjct: 3660 ISMGDVATLSVT-VIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGE 3718
Query: 181 YYVQAVND-----------------KNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKN 223
Y A ND + D +T + ++E +GGP P + P +
Sbjct: 3719 YTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRC 3778
Query: 224 TSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGI-------SDHNRRLTIPNPTG 276
+ E T+ V P + W K+ L + + + + +P
Sbjct: 3779 AQGLPAIFEYTV--VGEPAPT----VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQR 3832
Query: 277 SDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVP 336
D+G Y C+A + + A L VL E + D PC+AK P
Sbjct: 3833 EDSGLYICKA---ENMLGESTCAAELLVL--------------LEDTDMTDTPCKAKSTP 3875
Score = 44.3 bits (103), Expect = 0.001
Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 459 SLLISPTHISD-AGTYTCLATNSRGVDEASADLVVWARTR--ITKPPQDQSVIKGTQASM 515
+L+I + D G Y C A N G SA L V R I + + V G A
Sbjct: 4489 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKF 4548
Query: 516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISA 574
C + P V R+ W K G + IR + SL I +T D G YTC+ +
Sbjct: 4549 TCEIQSAPNV--RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4606
Query: 575 GGNDSRSAHLRV 586
G+ S +A L V
Sbjct: 4607 YGSVSCTATLTV 4618
Score = 42.7 bits (99), Expect = 0.004
Identities = 102/543 (18%), Positives = 186/543 (34%), Gaps = 78/543 (14%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDN 193
+ S P +V W+ +G ++ SS+I T + TL IL D+G Y N K
Sbjct: 26092 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG--- 26148
Query: 194 KTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKK 253
+ S TL V GG A SV + V++ + K
Sbjct: 26149 EASDYATLDV--TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK---------KT 26197
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSD----AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQ 309
+ S + + ++T + S A A L S+ + +
Sbjct: 26198 SEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR 26257
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVE---KLTRFRQRNDGGLQ 366
+ +P R +T + C G P P++TW + V+ ++T + ++ +
Sbjct: 26258 ILTKP-RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKST--FE 26314
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS 426
IS + D G + N+ G+ + L + +T V +
Sbjct: 26315 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKA--RVTE-----------KAVTSPPRV 26361
Query: 427 GAPRPAITWQKGERILASGSVQLPRF--TPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
+P P R+ + +V+ P+ +P S +SPT T
Sbjct: 26362 KSPEP--------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPT------------ 26401
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHP 544
E L V A +IT+ + ++ A + C V W KDG L H
Sbjct: 26402 EKVQHLPVSAPPKITQFLKAEA--SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHF 26459
Query: 545 RIRLDRNGS--LHISQTWSGDIGTYTCRVISAGGNDS----------RSAHLRVRQLPHA 592
+ +G+ L I+ D G Y C + GG +S H +V ++
Sbjct: 26460 QFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISET 26519
Query: 593 PEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE--MSENNAPWTVLLASVDPKATSV 650
+ T + R +P ++ + + +S ++ + A+ +P+ T++
Sbjct: 26520 KKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAI 26579
Query: 651 TVK 653
K
Sbjct: 26580 WTK 26582
Score = 40.8 bits (94), Expect = 0.015
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 11/145 (7%)
Query: 77 MITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE-----KHQSVSHGEAAV 131
+IT+L + +R + N G R V + E + SV G+
Sbjct: 16884 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16943
Query: 132 IRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVND 188
I P I+ P+P +TW +DG + ++RI +T TL I T D G+Y + N
Sbjct: 16944 IEVP-ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV 17002
Query: 189 KNGDNKTSQPITLTVENVGGPADPI 213
KT+ +T++ P P+
Sbjct: 17003 VG--QKTASIEIVTLDKPDPPKGPV 17025
Score = 40.4 bits (93), Expect = 0.019
Identities = 47/198 (23%), Positives = 74/198 (37%), Gaps = 30/198 (15%)
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
G L+ G P+P I W +L + S + SL+I T + D G YTC
Sbjct: 3663 GDVATLSVTVIGIPKPKIQWFFNG-VLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTC 3721
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVI-------------------------KG 510
+A+N G SA L + ++ K + +S + +G
Sbjct: 3722 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3781
Query: 511 TQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS--LHISQTWSGDIGTYT 568
A V +P T+ W K+ L T + I + NGS ++ D G Y
Sbjct: 3782 LPAIFEYTVVGEPAPTV--TWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYI 3839
Query: 569 CRVISAGGNDSRSAHLRV 586
C+ + G + +A L V
Sbjct: 3840 CKAENMLGESTCAAELLV 3857
Score = 40.4 bits (93), Expect = 0.019
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAG 179
++ G+ V+ A I P P+ +W + G+ I PS IT T L I DAG
Sbjct: 14084 TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAG 14143
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
Y + A N + + +TV +V GP P+ + + K T
Sbjct: 14144 EYTITATNP---FGTKVEHVKVTVLDVPGPPGPVEISNVSAEKAT 14185
Score = 40.0 bits (92), Expect = 0.025
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 20/175 (11%)
Query: 416 GMSVVLACETSGAPRPAIT-WQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAG 471
G S + C S P AIT W K S + P+ + G L I +SDAG
Sbjct: 4828 GSSAIFECLVS--PSTAITTWMKD----GSNIRESPKHRFIADGKDRKLHIIDVQLSDAG 4881
Query: 472 TYTCLATNSRGVDEASADLVV-WARTRITKPPQDQ-SVIKGTQASMVCGVTHDPRVTIRY 529
YTC+ ++A LVV R K +++ +V+KG + C + + V
Sbjct: 4882 EYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV---- 4937
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRS 581
+W KDG + E RI G +L I+ D GTYT V +A + S
Sbjct: 4938 VWRKDGKIV-VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSS 4991
Score = 39.3 bits (90), Expect = 0.043
Identities = 54/219 (24%), Positives = 84/219 (38%), Gaps = 29/219 (13%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---------KFSLEYRY 76
P F +PV + LEG G E W H+ +++ K
Sbjct: 1411 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 77 MITSLDRTHAGFYRCIVRNRMGA------LLQRQTEVQVAYMGSFEEGEKHQSVSHGEAA 130
+I + +G + + +NR G L E QV M F E K+ ++ G
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPM--FVEKLKNVNIKEGSRL 1527
Query: 131 VIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT-----LVILSTVAPDAGRYYVQA 185
++ R P P + W ++ I P I +E T L I STV+ D+ Y A
Sbjct: 1528 EMKV-RATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1586
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
+N K G + T + + VE A+P +I P+ T
Sbjct: 1587 IN-KAGRDTTRCKVNVEVEF----AEPEPERKLIIPRGT 1620
Score = 38.9 bits (89), Expect = 0.056
Identities = 39/150 (26%), Positives = 59/150 (39%), Gaps = 16/150 (10%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY-----MGSFEEGEKHQSVSH---G 127
+ +TSL+ +R +N G R+T V + + + Q H G
Sbjct: 23389 HTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAG 23448
Query: 128 EAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAI---TLENTLVILSTVAPDAGRYYVQ 184
+ P IA P P +WF G K+ S R+ + T L I T D G Y ++
Sbjct: 23449 RPVELVIP-IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23507
Query: 185 AVNDKNGDNKTSQPI-TLTVENVGGPADPI 213
KN TS+ I + ++ G P PI
Sbjct: 23508 L---KNVTGTTSETIKVIILDKPGPPTGPI 23534
Score = 38.9 bits (89), Expect = 0.056
Identities = 58/210 (27%), Positives = 85/210 (40%), Gaps = 29/210 (13%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSR-IAITLEN-----TLVILSTVAPDAGRYYVQAVNDKN 190
I P+P VTW++ G+KI P T E+ L I S D Y V A N K
Sbjct: 25408 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARN-KY 25466
Query: 191 GDNKTSQPITLTVENVGGPAD-PIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHI 249
G++ +T+T+ P D + P N G S V E + P L
Sbjct: 25467 GEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANAECQEGQS-VCFEIRVSGIPPPTLK- 25522
Query: 250 IWKKDGVLLSGGISDH-------NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYL 302
W+KDG LS G + L I + D GYY V +++ S A+L
Sbjct: 25523 -WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR---VTATNTAGSTSCQAHL 25578
Query: 303 SV----LEPPQF--VKEPERHITAEMEKVV 326
V + +F +E ERH+ +++K +
Sbjct: 25579 QVERLRYKKQEFKSKEEHERHVQKQIDKTL 25608
Score = 38.5 bits (88), Expect = 0.073
Identities = 48/178 (26%), Positives = 71/178 (39%), Gaps = 11/178 (6%)
Query: 401 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESG- 458
AP I TV G G P P W K G +I S + + P ++
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW--YWPEDNVC 2088
Query: 459 SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVI---KGTQASM 515
L+I D+ + A N G + A L+V A+ IT + Q V+ K T A+
Sbjct: 2089 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATF 2148
Query: 516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVI 572
C T +P V ++ W KDG + R+ DR L I + D Y+C ++
Sbjct: 2149 ECE-TSEPFVKVK--WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Score = 37.4 bits (85), Expect = 0.16
Identities = 40/183 (21%), Positives = 75/183 (40%), Gaps = 14/183 (7%)
Query: 40 EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGA 99
+G + +L E + W +N+E K + ++ I L +R N G
Sbjct: 24152 DGGKEILGYWVEYRQSGDSAWKKSNKERIK---DKQFTIGGLLEATEYEFRVFAENETGL 24208
Query: 100 LLQRQTEVQVAYMGSFEEGE------KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
R+T + + + E K + GEAA + +I P P + W+R G++
Sbjct: 24209 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKE 24267
Query: 154 IPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPA 210
+ S + ++ + +TL +++ D G Y A N+ G+ +TS + L P
Sbjct: 24268 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEV-GEVETSSKLLLQATPQFHPG 24326
Query: 211 DPI 213
P+
Sbjct: 24327 YPL 24329
Score = 37.0 bits (84), Expect = 0.21
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGL 370
EP R + E + C+ G P P + WY + ++ K RFR R DG L I
Sbjct: 1802 EPVRVLEGETAR---FRCRVTGYPQPKVNWYLNGQLIRKSK--RFRVRYDGIHYLDIVDC 1856
Query: 371 VPDDTGMFQCFARNAAGEVQTSTYLAV 397
DTG + A N G ++ L +
Sbjct: 1857 KSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 36.6 bits (83), Expect = 0.28
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 17/162 (10%)
Query: 56 LEFKWLHNN--------RELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEV 107
+E +WL NN ++ +R I + G YR I +++ + + ++
Sbjct: 6635 VEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK-----EARAKL 6689
Query: 108 QVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT 167
++A + ++ V G+ + P A +P+ + WF++ + + + +
Sbjct: 6690 ELAAAPKIKTADQDLVVDVGKPLTMVVPYDA-YPKAEAEWFKENEPLSTKTIDTTAEQTS 6748
Query: 168 LVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGP 209
IL D GRY + + +K+G K I L V +V GP
Sbjct: 6749 FRILEAKKGDKGRYKI-VLQNKHG--KAEGFINLKVIDVPGP 6787
Score = 36.2 bits (82), Expect = 0.36
Identities = 35/147 (23%), Positives = 56/147 (38%), Gaps = 10/147 (6%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE--------KHQSV 124
E +Y +T L +R + N G V E E + Q +
Sbjct: 10866 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 10925
Query: 125 SHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQ 184
G+ + A I P P+VTW ++ R P +RI +T + + + A + G Y
Sbjct: 10926 KVGDTLRLSAI-IKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10984
Query: 185 AVNDKNGDNKTSQPITLTVENVGGPAD 211
V + G +KT L ++ G P D
Sbjct: 10985 TVENPAG-SKTVSVKVLVLDKPGPPRD 11010
Score = 35.8 bits (81), Expect = 0.47
Identities = 62/277 (22%), Positives = 103/277 (37%), Gaps = 44/277 (15%)
Query: 318 ITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ---ISGLVPDD 374
+T + C K +TW + A ++E+ R +Q +G +Q I + D
Sbjct: 3498 VTVKCGDTAQFLCVLKDDSFIDVTWTHEGA--KIEESERLKQSQNGNIQFLTICNVQLVD 3555
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGM----SVVLACETSGAPR 430
G++ C N GE TS L+V +I ++ + M S L+ E G
Sbjct: 3556 QGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEMKEFSSSFLSAEEEG--- 3612
Query: 431 PAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADL 490
L S +QL + E+ LL S++ Y T E + +
Sbjct: 3613 -----------LHSAELQLSKIN--ETLELL------SESPVY---PTKFDSEKEGTGPI 3650
Query: 491 VVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR 550
+ K + + G A++ V P+ I+ W +G L + + D
Sbjct: 3651 FI-------KEVSNADISMGDVATLSVTVIGIPKPKIQ--WFFNGVLLTPSADYKFVFDG 3701
Query: 551 NG-SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
+ SL I T D G YTC + G SA+L++
Sbjct: 3702 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3738
Score = 35.4 bits (80), Expect = 0.61
Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 59 KWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEG 118
KW+ + + +E +T L+ YR NR GA + ++ + + E
Sbjct: 7328 KWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 7383
Query: 119 EKHQSVSHGEAAVIRA-------PRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTL 168
E V ++A + P+P++TW + + RI I ++T+
Sbjct: 7384 EIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTV 7443
Query: 169 VILSTVAPDAGRYYVQAVN 187
I+ + D G Y ++AVN
Sbjct: 7444 TIVDSKRSDTGTYIIEAVN 7462
Score = 35.0 bits (79), Expect = 0.80
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE--NTLVILSTVAPDAGRY 181
V GE A R R+ +PQP+V W+ +G+ I S R + + + L I+ + D G
Sbjct: 1806 VLEGETARFRC-RVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1864
Query: 182 YVQAVN 187
V A N
Sbjct: 1865 KVTAEN 1870
Score = 35.0 bits (79), Expect = 0.80
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDN 193
I S P + WF+ GR+I S + +I ++L IL T D G Y +A N+ +
Sbjct: 4552 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVS 4611
Query: 194 KTSQPITLTVENVGG 208
T+ TLTV GG
Sbjct: 4612 CTA---TLTVTVPGG 4623
Score = 35.0 bits (79), Expect = 0.80
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 505 QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD-RNGSLHISQTWSGD 563
+S G+ A C V+ +T W KDG+ + R D ++ LHI D
Sbjct: 4823 ESEFVGSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSD 4879
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLP 590
G YTC + + +A L V +LP
Sbjct: 4880 AGEYTCVLRLGNKEKTSTAKLVVEELP 4906
Score = 34.7 bits (78), Expect = 1.0
Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 53 SWPLEFKWLHNNREL-TKFS--LEYRYMITSLDRTHAGFYRCIVRNRMGALLQ-RQTEVQ 108
S+ +E + L N R L FS LE + ++ L A +R I +N GA+ +
Sbjct: 15085 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15144
Query: 109 VAYMGSFEEGEKHQSVSHGEAAVIRAPR-------IASFPQPQVTWFRDGRKIPPSSRIA 161
+ E + V + +++A ++ P P + W +DG+++ ++++
Sbjct: 15145 ITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE 15204
Query: 162 ITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTII 218
I + LV + D+G Y + A N G K + + ++ G P P+A T +
Sbjct: 15205 IKIADFSTNLVNKDSTRRDSGAYTLTATN-PGGFAKHIFNVKV-LDRPGPPEGPLAVTEV 15262
Query: 219 IPPK 222
K
Sbjct: 15263 TSEK 15266
Score = 34.7 bits (78), Expect = 1.0
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILS---TVAPDAGRYYVQAVNDKNGDNKTSQ 197
PQ V W +DG+ + ++R+ ++ T+ LS D G Y + N +
Sbjct: 19117 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV---SNSAGSITV 19173
Query: 198 PITLTVENVGGPADPI 213
PIT+ V + GP PI
Sbjct: 19174 PITIIVLDRPGPPGPI 19189
Score = 33.5 bits (75), Expect = 2.3
Identities = 57/314 (18%), Positives = 111/314 (35%), Gaps = 26/314 (8%)
Query: 94 RNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
R + GA Q E M SF +K + ++ E + + + S +V++F +
Sbjct: 4323 RIQQGAKTSLQEE-----MDSFSGSQKVEPITEPE---VESKYLIS--TEEVSYFNVQSR 4372
Query: 154 IPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENV-GGPADP 212
+ +T ++S D + + + ++ T + T+ ++ GG
Sbjct: 4373 VKYLDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKE 4432
Query: 213 IAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG-----ISDHNR 267
P I P +T G + NA+ + W + L+ + D N
Sbjct: 4433 DGPMIHTPLVDTVSEEGDIVHLTTSITNAK-----EVNWYFENKLVPSDEKFKCLQDQNT 4487
Query: 268 RLTIPNPTGSD--AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
+ + ++ G Y CEA+ S + + + P +K + + +
Sbjct: 4488 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP--VIKRKIEPLEVALGHL 4545
Query: 326 VDIPCQAKGVPPPSITWYKDAA-VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARN 384
C+ + P W+K + E +K + + L+I D G + C A N
Sbjct: 4546 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASN 4605
Query: 385 AAGEVQTSTYLAVT 398
G V + L VT
Sbjct: 4606 EYGSVSCTATLTVT 4619
Score = 33.5 bits (75), Expect = 2.3
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRI-AITLENT--LVILSTVAPDAG 179
+V GE + P I P P VTW +D + ++R+ A + EN L I D G
Sbjct: 15853 TVLAGEDLKVDVPFIGR-PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVG 15911
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPI 213
Y V+ N +T I L + G P P+
Sbjct: 15912 HYVVKLTNSAGEAIETLNVIVL--DKPGPPTGPV 15943
Score = 33.1 bits (74), Expect = 3.0
Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 18/155 (11%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQV-----AYMG-------SFEEGEK 120
E +++I+ L + +R RN +G++ V +Y G + E K
Sbjct: 20519 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVK 20578
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR 180
+++ G + +RA I+ P P + W++D +++ ++ + + ENT + S + DA R
Sbjct: 20579 YRA---GTSVKLRAG-ISGKPAPTIEWYKDDKELQTNALVCV--ENTTDLASILIKDADR 20632
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAP 215
K + S T+ V+ + P P P
Sbjct: 20633 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGP 20667
Score = 31.6 bits (70), Expect = 8.9
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 1/86 (1%)
Query: 427 GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA 486
G P + W + L + + +L SL + D+G TC ATN G D
Sbjct: 1684 GDPTMVVEWLHDGKPLEAAN-RLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHT 1742
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQ 512
SA L+V + + Q KG Q
Sbjct: 1743 SATLIVKDEKSLVEESQLPEGRKGLQ 1768
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 246 bits (629), Expect = 1e-64
Identities = 395/1726 (22%), Positives = 665/1726 (38%), Gaps = 198/1726 (11%)
Query: 147 WFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
W ++G ++P +R++ ++ + L I PD G Y V A DK S L +
Sbjct: 6394 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDK------SVAELLII 6447
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS 263
E APT + V + C + K ++ W ++G + G
Sbjct: 6448 E---------APTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKK 6495
Query: 264 ------DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE-PER 316
RL I + D Y C R S V + ++ PPQ + E P
Sbjct: 6496 YKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGA 6555
Query: 317 HIT--AEMEKVVDIPCQAKGVPPPSITWYKD-AAVVEVEKLTRFRQRNDGGLQISGLVPD 373
+ AE+ K + W ++ VV+ +K + LQI + P
Sbjct: 6556 DVVFLAELNK-----------DKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR 6604
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D G ++ A++ E + LA AP I D V G + + P+
Sbjct: 6605 DQGEYRFIAKDK--EARAKLELAA---APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEA 6659
Query: 434 TWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW 493
W K L++ ++ T E S I D G Y + N G E +L V
Sbjct: 6660 EWFKENEPLSTKTID----TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV- 6714
Query: 494 ARTRITKPPQDQSVIKGTQASMVCG----VTHDPRVTIRYIWEKDGATLGTESHPRIRLD 549
+ P ++ V + + +T I Y+ E+ T + D
Sbjct: 6715 --IDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV---LATD 6769
Query: 550 RNGSLHISQTWSGDIGT-YTCRV-----ISAGGNDSRSAHLRVRQLPHAPEHPV-ATLST 602
R S + T G Y RV + G + R P P+ T++
Sbjct: 6770 RAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITD 6829
Query: 603 VERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSY 661
V R ++LTW P +DG + + Y++E+ + + +V + S TV +V + Y
Sbjct: 6830 VNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEY 6889
Query: 662 QFRLCAVNDVGKGQFSKDTE--RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
FR+ A N +G G+ S T +V+ P E P+ PP N+ +S +T S+ ++W+PP +
Sbjct: 6890 SFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSSVQLKWEPPLKDGG 6948
Query: 720 NGILKGYIIRYCLAGLP--VGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
+ IL GYII C G + K + + LE Y V+A N AG+
Sbjct: 6949 SPIL-GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK---GNKYLYRVSAENKAGVSD 7004
Query: 778 YSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837
S + T P ++ A I P+P I + GY
Sbjct: 7005 PSEILGPLTADDAFVEPTMDLSAFKDGLEVI-----VPNPITILVPSTGYP--------- 7050
Query: 838 EEVTMVTARPNFQDSI-HVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG 896
TA F D + G +K + Y V+ + D T +L + + G
Sbjct: 7051 ----RPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7106
Query: 897 PVG-----------HLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR-TNTRVT 943
+ L F +I S+ ++W+ P + G LTGY + E +R T T+V
Sbjct: 7107 EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVM 7166
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA--STISSGVPPELPGPPTNLGI 1001
++ + LE+ V L Y +V A G G+ + ++ P +P PP N+
Sbjct: 7167 DFVTD--LEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKW 7224
Query: 1002 SNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS-MEVP 1059
+ S+ L + P DG + I ++VE ++W+ EP A + MEV
Sbjct: 7225 RDRTANSIFLTWDPPKNDGGSRIKGYIVER---CPRGSDKWVAC----GEPVAETKMEVT 7277
Query: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTL--QAPPDM-----APANVSLRTASETS 1112
L Y++R++ +N G S PS+P+ +IQ + Q P++ A ++++ ++
Sbjct: 7278 GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIE 7337
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER--DYTIEDLEEWTE 1170
L G PE KI ++++D K + + V + TI D +
Sbjct: 7338 L--------PATVTGKPEP---KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7386
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
++A N G T V P T+ S L+ W+ P D
Sbjct: 7387 GTYIIEAVNVCGRA----TAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP-PRDDGGS 7441
Query: 1231 LVLGYKVMYKEKDSDTQPRF-WLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-S 1288
+ Y V + DS+ + V+ + ++ +L +Y+ +V A G G P
Sbjct: 7442 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF---RVAAENMYGVGEPVQ 7498
Query: 1289 HPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTA 1348
PI + D PGPP + ++ +V L W P G + RL+ T
Sbjct: 7499 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7558
Query: 1349 TVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRP 1406
+ Y GL + Y FR+ A+ G G+ +++ ++ + D P PP +P
Sbjct: 7559 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKP 7618
Query: 1407 MVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDR 1465
V +DV SV L+W +P DG + + Y I+ + + W + V + ++
Sbjct: 7619 TV--KDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVP--TTQHLLPG 7674
Query: 1466 LKPFTSYKFRVKATNDIGDSEFSEESES-LTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
L Y FRV+A N G+SE SE S+ L + P P L V T + ++W
Sbjct: 7675 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 7734
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
P +D + + + R++ +G W + + + LT+
Sbjct: 7735 PEKDG-GSPITNYIVEKRDVRRKG---------------WQTVDTTVKDTKCTVTPLTEG 7778
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT--AAPRNVVVHGATATQLDV 1642
L Y R++ NA+G+ + ++ + + T P + V T +D+
Sbjct: 7779 SL--------YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7830
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
WEPP D IQ Y I E + KT + + ++ ++ T V A
Sbjct: 7831 KWEPPKNDG-GRPIQRYVIEKKERLGTRWVKAGKTAG-PDCNFRVTDVIEGTEVQFQVRA 7888
Query: 1703 FNAAGDGPRSTPTQ---GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
N AG G S PT+ + + PS P + ++ + ++W+ P+ G + GY
Sbjct: 7889 ENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYH 7948
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD-LAEGVTYRFRIRA 1803
+ E C PV G K + V+ + L KV++ + Y R+RA
Sbjct: 7949 V--EMC-PV-GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 7990
Score = 225 bits (573), Expect = 4e-58
Identities = 433/1960 (22%), Positives = 731/1960 (37%), Gaps = 276/1960 (14%)
Query: 72 LEYRYMITSLDRTHAGFYRCIVRNRMGAL---------LQRQTEVQVAYMGSFEEGEKHQ 122
+E ++ ++ L +R I +N GA+ + + EV++ + +
Sbjct: 17204 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 17263
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTLVILSTVAPDAG 179
V+ GE + A + P P + W R ++I S+R I + L++ + D G
Sbjct: 17264 VVNAGETFRLEAD-VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 17322
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVA 239
+Y ++A N S P+ + V + GP P V TSE
Sbjct: 17323 QYILRA---SNVAGSKSFPVNVKVLDRPGP----------PEGPVQVTGVTSE------- 17362
Query: 240 NARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAG-YYECEAVLRSSSVPSVVR 298
K + W L G SD + + T A E V S V ++
Sbjct: 17363 ------KCSLTWSPP---LQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLE 17413
Query: 299 G---AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV------ 349
G + + V EP M+ +P K + +I KD+ V
Sbjct: 17414 GNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIA--KDSMTVCWNRPD 17471
Query: 350 ----------EVEKLTRF---------RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQ 390
VEK R R+ D L+++GL D F+ A NAAG +
Sbjct: 17472 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17531
Query: 391 TS-TYLAVTSIAPNITRGP------LDST-----------VIDGMSVVLA-----CETSG 427
S + + P GP +D+T + DG S +L C+
Sbjct: 17532 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 17591
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA- 486
+T Q G R+ T E L T + C A N G+ EA
Sbjct: 17592 EEWQIVTPQTGLRV-----------TRFEISKL----TEHQEYKIRVC-ALNKVGLGEAT 17635
Query: 487 SADLVVWARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
S V ++ P D + ++ S + R T W ++
Sbjct: 17636 SVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---- 17691
Query: 541 ESHPRIRLDRNGS---LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
E ++++++ + L I D G Y ++ ++ G+ S ++V P P++
Sbjct: 17692 EFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-- 17749
Query: 598 ATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLV 656
+ V + + L W P DG + + Y+++ E+ ++S K TS V+ L
Sbjct: 17750 LAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLT 17808
Query: 657 PARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPE 716
Y FR+ A N+ G G + + V E P +PP V + + S + W+ P
Sbjct: 17809 EGAIYYFRVMAENEFGVGVPVETVDAVKAAE--PPSPPGKVTLTDVSQTSASLMWEKPEH 17866
Query: 717 SHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG 776
+ +L GY++ G ++ + ++ V N ++ L Y+ V AYN G
Sbjct: 17867 DGGSRVL-GYVVEMQPKGTE---KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKG-- 17920
Query: 777 VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF-------INGINQGYKL 829
++ + GVP + + T +++ +N S Q I I +
Sbjct: 17921 -----KSDPRVLGVPVIA-----KDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 17970
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
I+W ++ E T R N +++ V +K+ + T +T L
Sbjct: 17971 ISW--VKDGEPLKQTTRVNVEETA-TSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 18027
Query: 890 THEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLP 947
+ PG PVG + F E+ + +SW+ P G ++ Y + R T T ++
Sbjct: 18028 IVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMV 18083
Query: 948 NVTL---EYRVTGLTALTTYTIEVAAMTSKGQ-GQVSASTISSGVPPELPGPPTNLGISN 1003
+ T+ ++T L T Y + A G+ + + + P + PGPP +++
Sbjct: 18084 SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTS 18143
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I + +Q+ P DG T I + +E + E L + + L+
Sbjct: 18144 ISKDQMLVQWHEPVNDGGTKIIGYHLEQK-----EKNSILWVKLNKTPIQDTKFKTTGLD 18198
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPE 1122
Y F++ NIVG PS+ S + P P + ++ L+W +
Sbjct: 18199 EGLEYEFKVSAENIVGIGKPSKVSECF--VARDPCDPPGRPEAIVITRNNVTLKW---KK 18253
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G + GY ++ + G+ + + +E ++T+ L E Y +V A NA G
Sbjct: 18254 PAYDGGSKITGYIVE-KKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 18312
Query: 1183 --SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE--VPEADRNGLVLGYKVM 1238
S P + R+ + + N S ++V E V EAD G + V
Sbjct: 18313 NFSEPSDSSGAITARDEIDA---PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 18369
Query: 1239 YKE-KDSDTQPRFWLVEGNSSRSAQL------TGLGKYVLYEVQVLAFTRIGDGSPSHPP 1291
K+ K+ + ++ ++ + T G+Y+L V G P
Sbjct: 18370 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNV--------GGTKSIP 18421
Query: 1292 ILERTLDDVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATV 1350
I + LD PGPP G L V L W PP G +++ I + T+ + V
Sbjct: 18422 ITVKVLDR-PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 18480
Query: 1351 EVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTT-EKRDRPQPPSRPMVQ 1409
A Y T L P + Y+FR+ A + G GE E+ VT P PPS P V
Sbjct: 18481 ST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVS 18539
Query: 1410 QEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKP 1468
+ S++++W P DG + + Y ++ R+ RW + + V L
Sbjct: 18540 A--ITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDL-RLRVTGLTE 18596
Query: 1469 FTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAE 1527
SY+FRV A N G E SE S A P P+ VT + +SV + W P
Sbjct: 18597 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKP-- 18654
Query: 1528 DKINGILLGFRIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
+Y+G ++G+ + W T ++ Q+
Sbjct: 18655 -----------------IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG------KQF 18691
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAVP------TAAPRNVVVHGATA 1637
+ L ++ Y R+ N+ G G P++ P V E + A R VVV A+A
Sbjct: 18692 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18751
Query: 1638 T-QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE-NSVKLKNLTGYTA 1695
T +L VT + P WE G LT+R + + + + N+T + +
Sbjct: 18752 TLRLFVTIKGRPEPEVK----------WEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDS 18801
Query: 1696 YMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILE 1755
++ N +G T +PSAP ++ E+ SV +SWE P G
Sbjct: 18802 GRYNLTLENNSGS---KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGA-- 18856
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN 1815
++ + K + ++++L EG +Y FR+ A YG + A
Sbjct: 18857 --KITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASN-EYGIGLPAE 18913
Query: 1816 VTTGPGEGA--PGPPG-VPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDI 1871
TT P + + P PPG V ++ + I W + G IT YV+E + W
Sbjct: 18914 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 18972
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
+V + ++ L G Y FRV AVN+ G P
Sbjct: 18973 C-----TQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDP 19007
Score = 218 bits (556), Expect = 4e-56
Identities = 418/1900 (22%), Positives = 731/1900 (38%), Gaps = 252/1900 (13%)
Query: 136 RIASFPQPQVTWFRDGRKIPPS----------SRIAITLENTLVILSTVAPDAGRYYVQA 185
+I P P +TWF+ K P + +++ + TLVI + D G Y + A
Sbjct: 9767 KIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITA 9826
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTII------------IPPKNTSVVAGTSEV 233
VN+ +K + + +G P P+ P PPK+ T+ V
Sbjct: 9827 VNNLGTASKE-----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9881
Query: 234 TLECVANARPLIKLHIIWKKDGVLLSGGISDHNR--RLTIPNPTG-SDAGYYECEAVLRS 290
+ AN + + + K+ + + H R+ N G + E E
Sbjct: 9882 IEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 9941
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY--KDAAV 348
SVP + P +T E+ + G P + W KD
Sbjct: 9942 FSVPGAP--------DKPTVSSVTRNSMTVNWEEP-----EYDGGSPVTGYWLEMKDTTS 9988
Query: 349 VEVEKLTR--FRQRNDG-GLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIA 401
+++ R + G +++GL+ F+ +A NAAG + + A IA
Sbjct: 9989 KRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 10048
Query: 402 P---------NITRGPLD----STVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQ 448
P + T+ D + DG S V W+KG+ G+
Sbjct: 10049 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 10108
Query: 449 LPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE-ASADLVVWARTRITKPP----- 502
+ T L+ G+ + A N G+ E V+ + R+ P
Sbjct: 10109 V--VTGLKEGAFY----------KFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 10156
Query: 503 --QDQSVIK-GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
+D+ V+ G ++ V+ P T+ W + TL E+ + S+ I
Sbjct: 10157 SVRDRIVVHAGGVIRIIAYVSGKPPPTVT--WNMNERTLPQEATIETTAI-SSSMVIKNC 10213
Query: 560 WSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-G 618
G Y+ + G ++ + V +P P + + LTW P D G
Sbjct: 10214 QRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA-HNLTNESCKLTWFSPEDDG 10272
Query: 619 NSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS 677
SP+ Y++E E++ WT + +V + + TV+GL+ ++Y FR+ A N +G G F
Sbjct: 10273 GSPITNYVIEKRESDRRAWTPVTYTVTRQ--NATVQGLIQGKAYFFRIAAENSIGMGPFV 10330
Query: 678 KDTERVSLPEEPPTAP--PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGL 735
+ +E + + EP T P P+++ T ++ + W PP + G II Y L
Sbjct: 10331 ETSEALVI-REPITVPERPEDLEVKEVTKNTVTLTWNPP--KYDGG---SEIINYVLESR 10384
Query: 736 PVGYQ-FKNITDADV--NNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPT 792
+G + F +T+ ++ ++ L YE V+A N G G S T +
Sbjct: 10385 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKD--E 10442
Query: 793 VPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQ----EEEVTMVTARPN 848
+ P +H + + TIR +G + ++W ++ E++ T + P
Sbjct: 10443 LAPPTLHLDFRDKLTIRVGEAFALTGRYSG--KPKPKVSWFKDEADVLEDDRTHIKTTPA 10500
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILD 908
++ + + + + + V+ +T G R V + PVG +SF E+
Sbjct: 10501 ---TLALEKIKAKRSDSGKYCVVVENST---GSRKGFCQVNVVDRPGPPVGPVSFDEVTK 10554
Query: 909 TSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVTLEYRVTGLTALTTYTI 966
+ +SW+ P + G +T Y I +E + VT T +V+ L Y
Sbjct: 10555 DYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC--KVSKLLEGKDYIF 10612
Query: 967 EVAAMTSKGQGQVSASTISSGVPPE----LPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
+ A G +S +S + + +P P ++ + S + + +DG
Sbjct: 10613 RIHAENLYG---ISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKP 10669
Query: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
I+ +++E + + + W + + P + VPDL Y FR+ N +G P
Sbjct: 10670 ITNYILEKRETM---SKRWARVTKDPIHPYTK-FRVPDLLEGCQYEFRVSAENEIGIGDP 10725
Query: 1083 SQPSRKIQTLQ--APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR 1140
S PS+ + A P P N + S+ L W P ++G + +GY ++Y +
Sbjct: 10726 SPPSKPVFAKDPIAKPS-PPVNPEAIDTTCNSVDLTWQP---PRHDGGSKILGYIVEYQK 10781
Query: 1141 -SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRE 1196
D + +H + E Y + L + Y+ +V A NA G + + V+ + R
Sbjct: 10782 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10841
Query: 1197 SVPS-------SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD--TQ 1247
P + ++ T S +++ P KV +K++D D T+
Sbjct: 10842 EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP-----------KVTWKKEDRDAPTK 10890
Query: 1248 PRFWLVEGNSS---RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1304
R + S R+A G Y L + + + S ++ + D PGPP
Sbjct: 10891 ARIDVTPVGSKLEIRNAAHEDGGIYSL---------TVENPAGSKTVSVKVLVLDKPGPP 10941
Query: 1305 MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
+ E+R S L W+ P G ++ + R + +A + + + + + A
Sbjct: 10942 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK-KSHFAKH 11000
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSW- 1422
L + YLFR+ A+ + G G E + D PP P + DV V L W
Sbjct: 11001 LNEGNQYLFRVAAENQYGRGPFVET-PKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 11059
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
+P DG SP+ Y ++ +E + W + +V L+ +Y+FRVKA N +
Sbjct: 11060 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC---VVTGLQQGKTYRFRVKAENIV 11116
Query: 1483 GDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK----INGILL--G 1536
G PD + P L+ PP+ + I G+++ G
Sbjct: 11117 G--------------LGLPD------TTIPIECQEKLV---PPSVELDVKLIEGLVVKAG 11153
Query: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWA------ELTSMYSMRNLSRPSLTQYELDNLN 1590
+R+ ++ RG+ P A W + Y++ + S+ + N
Sbjct: 11154 TTVRFPAII---------RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT--IKNCL 11202
Query: 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+ E +++V NA G + V PT P N++ T + ++W+PP D
Sbjct: 11203 RRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINIL--DVTPEHMTISWQPPK-D 11258
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
+ Y + + ++ T V + ++ +K+ +L Y+ V A N G GP
Sbjct: 11259 DGGSPVINYIVEKQDTRKD--TWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGP 11316
Query: 1711 R--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPV 1767
STPT + + + PS P +++T + VSW P+ G + GY Y V
Sbjct: 11317 PLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGY---YMERREV 11373
Query: 1768 DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTTGPGEG 1823
G K V V+ + L +V L EG TY FR+ A+ P + P +
Sbjct: 11374 TG--KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK- 11430
Query: 1824 APGPPGVPIIVRYSSAIA-IHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
PGPP P + S A + W+ G PI YV+E + W+ + KD + +
Sbjct: 11431 PPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD--ELIR 11488
Query: 1882 SYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
F + L G Y FR+ A N G G P ++SV A+
Sbjct: 11489 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAK 11528
Score = 215 bits (548), Expect = 3e-55
Identities = 424/1882 (22%), Positives = 697/1882 (37%), Gaps = 278/1882 (14%)
Query: 378 FQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMSVVLACETSGAP 429
F+ A+N AG E +S + I P + + +I G + SG P
Sbjct: 22244 FRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRP 22303
Query: 430 RPAITWQKGE-RILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASA 488
P +TW+ E R+ + V + T + +L + + D+G Y N+ GV S
Sbjct: 22304 APKVTWKLEEMRLKETDRVSIT--TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV 22361
Query: 489 DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--IRYIWEK--DGATLGTESHP 544
+VV R P + S + + G D T YI EK G T +
Sbjct: 22362 TVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNS 22421
Query: 545 RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLST-- 602
++ + H+++ Y+ RV S + + P EHP S
Sbjct: 22422 SVKRTQIKVTHLTKYME-----YSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPT 22473
Query: 603 ------VERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGL 655
V A+++ W +P+ DG S +I Y +E E N V V + V GL
Sbjct: 22474 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22533
Query: 656 VPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPP 715
V YQFR A+N G + S + R + + P AP + + T ++ + W P
Sbjct: 22534 VEGLEYQFRTYALNAAGVSKAS-EASRPIMAQNPVDAPGRPEVTDV-TRSTVSLIWSAPA 22591
Query: 716 ESHQNGILKGYII-RYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSA 773
+ ++ GYII R ++ + G K N T N + L YE V A N+A
Sbjct: 22592 YDGGSKVV-GYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAA 22650
Query: 774 GLGVYSSKVTEWTLQGVPTVPP-----GNVHAEATNSTTIRFTWNAPSPQFINGINQGYK 828
G+ S+ T PP +H + TIR + + G + K
Sbjct: 22651 GVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV---TIRAGSDLVLDAAVGGKPEP-K 22706
Query: 829 LIAWEPEQE----EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRST 884
+I + ++E E+V++ I S K+T + G ++
Sbjct: 22707 IIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA-------SGTKAV 22759
Query: 885 PQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVT 943
+V+ D PGP G L+ S + ++W P E G +T Y + E +R N +
Sbjct: 22760 SVMVKVL-DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 22818
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG-QVSASTI---SSGVPPELPGPPTNL 999
TL Y VT L Y V A+ G G V + I +S P PG P +
Sbjct: 22819 EG-ECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEV 22877
Query: 1000 GISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEV 1058
G G + +Q+ +P DG IS +LV+ + + W +++ D R ++V
Sbjct: 22878 GT---GKEHIIIQWTKPESDGGNEISNYLVDKREK---KSLRWTRVNKDYVVYDTR-LKV 22930
Query: 1059 PDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP----PDMAPANVSLRTASETSLW 1114
L Y FR+ VN G S PS+ S I + P AP V S + W
Sbjct: 22931 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 22990
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
+ M Y+G + VGY ++ D H ++T+ DL+ +Y +
Sbjct: 22991 TKPM------YDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFR 23044
Query: 1175 VQAFNAIGSGPWSQTVVGRT---RESVPSSGPTN-----VSALATTSSSMLVRWSEVPEA 1226
V A N G +S+++ R +P + V+ A S ++V S P
Sbjct: 23045 VAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP 23104
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
+ + ++ D R + +++ S L + K Y+
Sbjct: 23105 ---------VITWSKQGIDLASRAII---DTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23152
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+L + D PGP + EV SV + W+ P G + I +
Sbjct: 23153 KKSATVLVKVYD-TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRA 23211
Query: 1347 TATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPS 1404
TV S Y +GL ++Y FR+ + G GE E V+ +E P P+
Sbjct: 23212 FKTVTTKC-SKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PLVPA 23267
Query: 1405 RPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
+ ++ DV +V L+WE P DG S + Y ++ + + RW + ++ V
Sbjct: 23268 K--LEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW-MKVVTLKPTVLEHTV 23324
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRW 1522
L Y FR++A N+ G SE E ++T PTI LS P T V
Sbjct: 23325 TSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRV--LPTIDLSTMPQKTIHV---- 23378
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLT 1582
PA + ++ + G P A+W S +R R ++
Sbjct: 23379 --PAGRPVELVI------------------PIAGRPPPAASWFFAGS--KLRESERVTVE 23416
Query: 1583 QYELDNLNKHRRYEIRMSVYNAVGE---------GPSSPPQEVFV-GEAVPTAAPRNVVV 1632
+ K + IR + GE G +S +V + + P P + +
Sbjct: 23417 TH-----TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP--IKI 23469
Query: 1633 HGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTG 1692
AT + ++WEPP LD + GY + +A R +++ ++ K LT
Sbjct: 23470 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTE 23526
Query: 1693 YTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Y+ VAA N G G +S + ++ P P +++ +++ + ++W P+
Sbjct: 23527 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23586
Query: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
G V+ + + + W++V + +T R R+ T G
Sbjct: 23587 GG---------------SQVTGYIVERKEVRADRWVRVNKVPVTMT---RYRSTGLTEGL 23628
Query: 1811 EIEANVTT--GPGEGAPGPPGVPIIVR-----------------YSSAIAIHWS-SGDPG 1850
E E VT G G P P PI+ +++++ WS D G
Sbjct: 23629 EYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEG 23688
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
+T Y+IE + D+ W P ++ YT + L G Y FRV+A N G G
Sbjct: 23689 GSKVTGYLIEMQKVDQHEWT-KCNTTPTKIREYTLTH--LPQGAEYRFRVLACNAGGPGE 23745
Query: 1911 PSSPSQSV--------PAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAK 1962
P+ +V P + + Y+E F+ ++ L + I+G+ K
Sbjct: 23746 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRL--------TIPIKGKPFPICK 23797
Query: 1963 KTDSGNSAKSGAL-----GHSEMMSLD----ESSFPALELNNRRLSVKNSFCRKNGLYTR 2013
T G A+ H+E++ + +S L L N+ C K +Y +
Sbjct: 23798 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENK--------CGKKAVYIK 23849
Query: 2014 SPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSF 2073
SP S E +Y+D I S ++ +P +D G+D +
Sbjct: 23850 VRVIGSPN----SPEGPLEYDD-IQVRSVRVSWRPP--ADDGGADI---------LGYIL 23893
Query: 2074 VNHYISDPTYYNSWRRQQ------KGISRAQAYSYTESDSGEPDHTTVTNSTSTQQGSLF 2127
+ +Y R + KG+ Y + S + Q +
Sbjct: 23894 ERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVS--------------AENQFGIS 23939
Query: 2128 RPKASRTP----TPQNPPNPPS 2145
+P S P TP NPP PPS
Sbjct: 23940 KPLKSEEPVTPKTPLNPPEPPS 23961
Score = 213 bits (541), Expect = 2e-54
Identities = 413/1864 (22%), Positives = 693/1864 (37%), Gaps = 243/1864 (13%)
Query: 147 WFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
WFR+ I SS+ I ++ TL I D Y V N + + K++ + +
Sbjct: 6300 WFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEE 6359
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV------L 257
E++ I+ P K+ + S VT C N + + + W K+G
Sbjct: 6360 EDL---------RIVEPLKDIETMEKKS-VTFWCKVNR---LNVTLKWTKNGEEVPFDNR 6406
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP-QFVKEPER 316
+S + + LTI + D G Y ++ + SV A L ++E P +FV+ E
Sbjct: 6407 VSYRVDKYKHMLTIKDCGFPDEGEY----IVTAGQDKSV---AELLIIEAPTEFVEHLED 6459
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ---ISGLVPD 373
E + V CQ ++ WY++ E+++ +++ DG + I D
Sbjct: 6460 QTVTEFDDAV-FSCQLSR-EKANVKWYRNGR--EIKEGKKYKFEKDGSIHRLIIKDCRLD 6515
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D + C + + L V I I R P D G VV E + + +
Sbjct: 6516 DECEYACGVEDRKSRAR----LFVEEIPVEIIRPPQDILEAPGADVVFLAELN-KDKVEV 6570
Query: 434 TWQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAGTYTCLATNSRGVDEASADL 490
W + ++ G + + G L I D G Y +A + EA A L
Sbjct: 6571 QWLRNNMVVVQGD----KHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKL 6622
Query: 491 VVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR 550
+ A +I QD V G +MV V +D W K+ L T++
Sbjct: 6623 ELAAAPKIKTADQDLVVDVGKPLTMV--VPYDAYPKAEAEWFKENEPLSTKTIDTTA--E 6678
Query: 551 NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER--RAI 608
S I + GD G Y + + G +L+V +P PV L E +
Sbjct: 6679 QTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPG----PVRNLEVTETFDGEV 6734
Query: 609 NLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPAR-SYQFRLC 666
+L W +P DG S +I Y++E + T +LA+ ++ TV GL Y FR+
Sbjct: 6735 SLAWEEPLTDGGSKIIGYVVERRDIKRK-TWVLATDRAESCEFTVTGLQKGGVEYLFRVS 6793
Query: 667 AVNDVGKGQ-FSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKG 725
A N VG G+ D + + PP NV + + + W+ PPE +
Sbjct: 6794 ARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWE-PPEYDGGAEITN 6852
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
Y+I + + A+ + + D++ Y V A N G+G S T +
Sbjct: 6853 YVIE-LRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVG-KPSAATPF 6910
Query: 786 TLQGVP---TVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
P PP N+ + ++++ W P + G ++ + E+ EE
Sbjct: 6911 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK------DGGSPILGYIIERCEEGKD 6964
Query: 843 VTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHL 901
R N + + + V+GL+K +Y V G V ++ GP+
Sbjct: 6965 NWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG---------VSDPSEILGPL--T 7013
Query: 902 SFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLE----YRVTG 957
+ ++ ++ +S + G + + I T + LE ++
Sbjct: 7014 ADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKT 7073
Query: 958 LTALTTYTIEVAAMTSKG----QGQVSASTISSGVPPEL---PGPPTNLGISNIGPRSVT 1010
L+A I + + KG + + TIS + + P P L +I SV
Sbjct: 7074 LSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVH 7133
Query: 1011 LQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSF 1069
L + P DG + ++ ++VE + + W + + + VPDL Y F
Sbjct: 7134 LTWEPPDDDGGSPLTGYVVEKR---EVSRKTWTKVMDFVTDLE---FTVPDLVQGKEYLF 7187
Query: 1070 RMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
++ N G P+ + T PD P NV R + S++L W P + +G
Sbjct: 7188 KVCARNKCGPGEPAYVDEPVNMSTPATVPD-PPENVKWRDRTANSIFLTWDP---PKNDG 7243
Query: 1128 NPESVGYKIKY--SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
GY ++ SD V + ++E + LEE Y +V+A N G
Sbjct: 7244 GSRIKGYIVERCPRGSDKWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASK 7299
Query: 1183 -SGPWSQTVVGRTRE--------------SVPSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
S P + T+E +V + + A T + W++
Sbjct: 7300 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKA---- 7355
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++L ++ + +V+ S + G Y++ V V
Sbjct: 7356 --DMILKQDKRITIENVPKKSTVTIVDSKRSDT------GTYIIEAVNVCG--------- 7398
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILA----------YQIT 1337
++E + D PGPP +V S L W PP G + ++
Sbjct: 7399 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 7458
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKR 1397
H+L++T +T + AT L P Y+FR+ A+ G GE +A +T + +
Sbjct: 7459 HKLSSTVKDT-----------NFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ 7507
Query: 1398 -DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
D P PP+R ++ D+ +V L+W EP DG SP+ Y ++ + + +W + +
Sbjct: 7508 FDPPGPPTR--LEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW-VRCNKMP 7564
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVT 1511
+++ V L Y+FRV A N G + S+ +E + P PT+ V
Sbjct: 7565 VKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDV- 7623
Query: 1512 PHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMY 1571
TSV + W P D G +I + + + W
Sbjct: 7624 --GKTSVRLNWTKPEHDG------GAKI----------ESYVIEMLKTGTDEW------- 7658
Query: 1572 SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAV-PTAAPRN 1629
+R TQ+ L L + + Y R+ N GE PS P V E + P + PR
Sbjct: 7659 -VRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRW 7717
Query: 1630 VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKN 1689
+ V T D+ W P D I Y + + +R + V T + + +
Sbjct: 7718 LEVINITKNTADLKWTVPEKDG-GSPITNYIVEKRDVRRKG-WQTVDTT-VKDTKCTVTP 7774
Query: 1690 LTGYTAYMVSVAAFNAAGDGPRS---TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEA 1746
LT + Y+ VAA NA G + + P P ++ ++T V++ WE
Sbjct: 7775 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEP 7834
Query: 1747 PQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTF 1806
P+ G R V E + ++ V +V D+ EG +F++RA+
Sbjct: 7835 PKNDGG-RPIQRYVIEKKERLG--TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENE 7891
Query: 1807 TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA----IAIHWSSGDP-GKGPITRYVIEA 1861
E PP P+ + + A IAI W + G PI Y +E
Sbjct: 7892 AGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM 7951
Query: 1862 RPSDEGLWDIL----IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
P W + IKD+ +V + + P Y RV AVN G PS S++
Sbjct: 7952 CPVGTEKWMRVNSRPIKDLKFKVE------EGVVPDKEYVLRVRAVNAIGVSEPSEISEN 8005
Query: 1918 VPAQ 1921
V A+
Sbjct: 8006 VVAK 8009
Score = 213 bits (541), Expect = 2e-54
Identities = 357/1619 (22%), Positives = 619/1619 (38%), Gaps = 152/1619 (9%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQ--TSTYLAVTSI----APNITRGPLDSTVI---DGM 417
+SGLV D F+ ARNAAG + + A+T+ APN + P VI G
Sbjct: 18292 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGE 18351
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ VL + G P P + W K + L + ++ + ++ +L++ +D G Y
Sbjct: 18352 TFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 18411
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT------IRYIW 531
+N G + V R PP+ + G A C + +P + YI
Sbjct: 18412 SNVGGTKSIPITVKVLDRPG---PPEGPLKVTGVTAEK-CYLAWNPPLQDGGANISHYII 18467
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAHLRVR 587
EK + + + + +L+ T Y RV++ G S +
Sbjct: 18468 EKRETSRLSWTQVSTEVQ---ALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC 18524
Query: 588 QLPHAPEHPVAT--LSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVD 644
P+ P P +T +S + + ++ +TW +P D G + + YILE +
Sbjct: 18525 N-PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT 18583
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQNVIASGRT 703
+ V GL SY+FR+ A N G G+ S+ + + P PP N + +
Sbjct: 18584 LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 18643
Query: 704 NQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGL--------PVGYQFKNITDADVNNLLL 754
S+ + W P + G +KGY++ A P G Q K T +
Sbjct: 18644 RSSVSLAWSKP--IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN-- 18699
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
T Y + A NS G+G ++ Q + P + +A + +A
Sbjct: 18700 ------TEYNFRICAINSEGVGEPATLPGSVVAQ--ERIEPPEIELDADLRKVVVLRASA 18751
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
F+ + + WE + E + A+ S + + + +F ++
Sbjct: 18752 TLRLFVTIKGRPEPEVKWE--KAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 18809
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G ++ VR + PV +L+ E+ S+ +SW+ P G +T Y +
Sbjct: 18810 NNSGS--KTAFVNVRVLDSPSAPV-NLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18866
Query: 934 EYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R +T+ T +R+ L +Y V A G G + A T E
Sbjct: 18867 ETTRKAYATITNNCTKTT--FRIENLQEGCSYYFRVLASNEYGIG-LPAETTEPVKVSEP 18923
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
P PP + + ++ + T+++ +P DG + I+ ++VE Q E+W Q+
Sbjct: 18924 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKT-- 18978
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTAS 1109
+ L Y FR+ VN G S P Q + + ++ P + + +
Sbjct: 18979 --LEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKA 19036
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
L + ++ + G P++ + + + G+TL + V T+ L
Sbjct: 19037 REQLKI------DVPFKGRPQAT---VNWRKD---GQTLKETTRVNVSSSKTVTSLSIKE 19084
Query: 1170 EYRVQVQAF-----NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVP 1224
+ V + N+ GS T++ R P GP + ++ S+ + W+ P
Sbjct: 19085 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP--GPIRIDEVSC--DSITISWNP-P 19139
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV--EGNSSRSAQLTGLGKYVLYEVQVLAFTRI 1282
E D + Y V KE S T W + + + S ++ L Y+ +V A R
Sbjct: 19140 EYDGGCQISNYIVEKKETTSTT----WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19195
Query: 1283 GDGSPSHPP-ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL 1340
G S S ++ PGPP +++ + WQ P G ++ Y + ++
Sbjct: 19196 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19255
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + ++L Q +GL +Y +R+ A+ G G+ +++ RD
Sbjct: 19256 RSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPC 19313
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP +P V ++ +SV L W +P DG + + Y ++ RELP GRW L + +
Sbjct: 19314 DPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW-LKCNYTNIQET 19370
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
F V L Y+FRV A N SE SES + D P + + ++
Sbjct: 19371 YFEVTELTEDQRYEFRVFARN--AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIV 19428
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
++ KIN + G R ++ G + + ++ ++++ R
Sbjct: 19429 VKAGEVL--KINADIAG---RPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRR 19483
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1639
QY L N + ++ GP + P E+ +G TA +
Sbjct: 19484 DTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEI----------------NGLTAEK 19527
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
++W P D DI Y + + + +L + L S K+ L Y+
Sbjct: 19528 CSLSWGRPQEDG-GADIDYYIVE--KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFR 19584
Query: 1700 VAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEG 1756
V N G G S + PS P+S++ + +T S+ + W P+ G + G
Sbjct: 19585 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19644
Query: 1757 YRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT---FTYGPEIE 1813
Y + + + + V V+ K L +K L EG Y +R+ A+ + E
Sbjct: 19645 YIIERREKNSL----RWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETS 19700
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDI 1871
+ P PP P IV + I I W G PIT Y +E + SD+ W
Sbjct: 19701 PLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKT 19760
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS--QSVPAQKANPFYE 1928
I+ + + YT S L G Y FRV +VN G PS S Q ++ P ++
Sbjct: 19761 SIQSL--RGTEYTISG--LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD 19815
Score = 211 bits (538), Expect = 5e-54
Identities = 373/1635 (22%), Positives = 612/1635 (37%), Gaps = 185/1635 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQ-----TSTYLAVTSIAPNITRGPLDS---- 411
+D ++ L DT F+ A+NAAG + T AP + LD+
Sbjct: 22625 SDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAP--PKAELDARLHG 22682
Query: 412 ---TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHIS 468
T+ G +VL G P P I W KG++ L ++T + + +I S
Sbjct: 22683 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG-KRATAVIKFCDRS 22741
Query: 469 DAGTYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGT--QASMVCGVT 520
D+G YT N+ G S + V + +++ Q++ + + Q +T
Sbjct: 22742 DSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEIT 22801
Query: 521 H---DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG-- 575
H + R T R W T S+ RL +N Y RV +
Sbjct: 22802 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNE-------------YIFRVRAVNKY 22848
Query: 576 --GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEM 629
G S + R +P P P + E I + WTKP DG + + Y+++
Sbjct: 22849 GPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH--IIIQWTKPESDGGNEISNYLVDK 22906
Query: 630 SENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE 688
E + WT + T + V L+ YQFR+ AVN G + S+ + +S E
Sbjct: 22907 REKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP 22966
Query: 689 PPT-APPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
T PP T SI + W P I+ GY++ Y+ T+A
Sbjct: 22967 SYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIV-GYVLEMQEKDTDQWYRVH--TNA 23023
Query: 748 DVNN--LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNS 805
+ N + DL + Y VAA N G+ YS + E +P + + +
Sbjct: 23024 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 23083
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
TIR A ++ + +I W + + + S+ + + K
Sbjct: 23084 VTIRA--GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-----VDKVN 23136
Query: 866 EYFTSVLCFTTPGD-GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y G +S LV+ + D PGP + E+ S+ ++W+ P G
Sbjct: 23137 RYDAGKYTIEAENQSGKKSATVLVKVY-DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23195
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + E + + TL YR++GL T Y V G G+ T
Sbjct: 23196 PVNNYIVEKREAAMRAFKTVTTKCSKTL-YRISGLVEGTMYYFRVLPENIYGIGE-PCET 23253
Query: 984 ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEA-QVGVVGEGEEW 1041
+ + E+P P L + ++ +VTL + +P YDG + ++ +++EA + G E W
Sbjct: 23254 SDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT----ERW 23309
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQTLQAPPDMA 1099
+ + L +P V LN Y FR+R N G S P + + +Q L+ P +
Sbjct: 23310 MKVVTL--KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTID 23367
Query: 1100 PANVSLRTAS-------ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS---DGHGKTLS 1149
+ + +T E + + P P + G K++ S + H K
Sbjct: 23368 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWF----FAGSKLRESERVTVETHTKVAK 23423
Query: 1150 HVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
+ R+ TI D E+T ++ N G+ + V+ + P +GP + +
Sbjct: 23424 LTI-----RETTIRDTGEYT-----LELKNVTGTTSETIKVIILDKPG-PPTGPIKIDEI 23472
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGK 1268
TS + + W E PE D + GY V E+ +P + V + +RS + T L +
Sbjct: 23473 DATS--ITISW-EPPELDGGAPLSGYVV---EQRDAHRPGWLPVSESVTRSTFKFTRLTE 23526
Query: 1269 YVLYEVQVLAFTRIGDGSPSHPPILE-RTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAP 1327
Y +V A R G GS ++E R+ +PGPP + +V + L W PP
Sbjct: 23527 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23586
Query: 1328 NGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA 1387
G + I R V + + +Y +TGL Y R+TA +G G+ +
Sbjct: 23587 GGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPS 23646
Query: 1388 EAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPS 1444
+V + P P P V D SV L+W P +G S V Y I+ +++
Sbjct: 23647 RPSKPIVAMDPIAPPGKPQNPRV--TDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ 23704
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEA 1504
W + + + + + L Y+FRV A N G E P E
Sbjct: 23705 HEWTKCNTTPT-KIREYTLTHLPQGAEYRFRVLACNAGGPGE--------------PAEV 23749
Query: 1505 PTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-----FTLRGINN 1559
P + VT ++ + D+ RY+E ++ G ++G
Sbjct: 23750 PGTVKVTE------MLEYPDYELDE----------RYQEGIFVRQGGVIRLTIPIKGKPF 23793
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
P W + S R + S T EL R Y+ V E + V++
Sbjct: 23794 PICKWTKEGQDISKRAMIATSETHTELVIKEADRG---DSGTYDLVLENKCG-KKAVYIK 23849
Query: 1620 EAV---PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG---NLTE 1673
V P + + + V+W PP D DI GY + E + +
Sbjct: 23850 VRVIGSPNSPEGPLEYDDIQVRSVRVSWR-PPADDGGADILGYILERREVPKAAWYTIDS 23908
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQAAPSAPSS- 1729
RV+ S+ +K L Y V+A N G P +T P PS+
Sbjct: 23909 RVR-----GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP 23963
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ ++T +SV++SW P+ G + GY + + S K V + + V
Sbjct: 23964 PEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETS----TDKWVRHNKTQITTTMYTV 24019
Query: 1789 KDLAEGVTYRFRIRAKT----FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHW 1844
L Y+FRI A+ P E V P + P + I+ ++ + W
Sbjct: 24020 TGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQW 24079
Query: 1845 SSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAV 1903
+ G I Y +E R S + W K + + F++ L Y+FRV A
Sbjct: 24080 EKPECDGGKEILGYWVEYRQSGDSAWK---KSNKERIKDKQFTIGGLLEATEYEFRVFAE 24136
Query: 1904 NDYGFGTPSSPSQSV 1918
N+ G P + S+
Sbjct: 24137 NETGLSRPRRTAMSI 24151
Score = 211 bits (537), Expect = 6e-54
Identities = 408/1878 (21%), Positives = 683/1878 (36%), Gaps = 218/1878 (11%)
Query: 136 RIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGD 192
R+ P+P +TW ++G+ + R+ + + L I V D G+Y + A KN
Sbjct: 11559 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISA---KNSS 11615
Query: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKL 247
+ V + GP + T + T + G SE+T V +P K
Sbjct: 11616 GHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQK- 11674
Query: 248 HIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP 307
W S SD +RL N ++ Y+ A + P++ + + P
Sbjct: 11675 --GW-------SIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINP 11725
Query: 308 PQFVKEPER-HITAEMEKVVDIPCQAKGVP--PPSITWYKDAAVVEVEKLTRFRQRN--D 362
EPE HI + + V + + P+++++ + + + R + + +
Sbjct: 11726 IDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKE 11785
Query: 363 GGLQISGLVPDDTGMFQCFARNAAGE---VQTSTYLAVTSIAPNITRGPLDS--TVIDGM 417
+ V + F+ +N GE V+T + + + L TV G
Sbjct: 11786 THYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11845
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRF---TPLESGSLLISPTHISDAGTYT 474
++ L G P P + W K + A+ + PR T +S ++ SD G Y
Sbjct: 11846 TIRLEAGVRGKPFPEVAWTKDKD--ATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11903
Query: 475 CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPR---------- 524
ATN+ G A A + V + KP +++ +S C V DP
Sbjct: 11904 VTATNTAGSFVAYATVNV-----LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQN 11958
Query: 525 ------VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGND 578
T R +W AT+ T RL IGT +
Sbjct: 11959 YILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGT-------GPPTE 12011
Query: 579 SRSAHLRVR-QLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP- 635
S+ + + P P+ P T V + + + W P +DG + Y LE E ++
Sbjct: 12012 SKPVIAKTKYDKPGRPDPPEVT--KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 12069
Query: 636 WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--PEEPPTAP 693
W + S P+ + V+ L+P YQFR+ A N++G G+ S + V P EPP P
Sbjct: 12070 WVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP-GP 12127
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII---------------RYCLAGLPVG 738
P N T SI + W P I+ GY++ + C A +
Sbjct: 12128 PTNFRVVDTTKHSITLGWGKPVYDGGAPII-GYVVEMRPKIADASPDEGWKRCNAAAQLV 12186
Query: 739 YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV 798
+ +T D N YE V A N G+G +++ E ++ + P +
Sbjct: 12187 RKEFTVTSLDENQ----------EYEFRVCAQNQVGIG-RPAELKE-AIKPKEILEPPEI 12234
Query: 799 HAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFV 858
+A+ + P F + + W + V R D +
Sbjct: 12235 DLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNV----VRKGQVDLVDTMAF 12290
Query: 859 SGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP 918
+ T + T + D PGPV L S++ TS VSW P
Sbjct: 12291 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPP 12350
Query: 919 GEKNGI-LTGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
G +T Y + E +R T + VT + + + VT L Y V A+ G
Sbjct: 12351 ENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS--FHVTNLVPGNEYYFRVTAVNEYGP 12408
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLV--EAQ 1031
G + + + P P PP L ++ + S TL + P DG I ++ +
Sbjct: 12409 GVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREE 12468
Query: 1032 VGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS---RK 1088
E+ ++ L S+ V L Y FR+ N VG S P +
Sbjct: 12469 EQPADRWTEYSVVKDL-------SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12521
Query: 1089 IQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
+ L P + P ++++ + + E G P K+ + + T
Sbjct: 12522 KEQLLPPKILMPEQITIKAGKKLRI--------EAHVYGKPHPT---CKWKKGEDEVVTS 12570
Query: 1149 SHVVQDRVERD--YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNV 1206
SH+ + + I+D+ + A N+ G+ VV P P ++
Sbjct: 12571 SHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG-PPQPPFDI 12629
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL-----VEGNSSRSA 1261
S + + S+ W +P D + Y V + D W+ V S R
Sbjct: 12630 SDIDADACSL--SW-HIPLEDGGSNITNYIV----EKCDVSRGDWVTALASVTKTSCRVG 12682
Query: 1262 QLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLI 1320
+L +Y+ +V A R G P + P ++ + VP P +V + +
Sbjct: 12683 KLIPGQEYIF---RVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVA 12739
Query: 1321 WQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
W P + G I+ Y I + + + L S +Y GL Y FRI A
Sbjct: 12740 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRST-EYPCAGLVEGLEYSFRIYALN 12798
Query: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQ 1438
+ G ++ T R PP +P V DV +V L W P DG S + Y ++
Sbjct: 12799 KAGSSPPSKPTEYVT-ARMPVDPPGKPEV--IDVTKSTVSLIWARPKHDGGSKIIGYFVE 12855
Query: 1439 TRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTL 1497
+LP +W ++A + L+ Y+FR A + S SE S+ +T L
Sbjct: 12856 ACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL 12915
Query: 1498 QAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
+V P SV ++ + N L T+ G
Sbjct: 12916 AE---------NVPPRIDLSVAMKSLLTVKAGTNVCL----------------DATVFGK 12950
Query: 1558 NNPGATWAE----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPP 1613
P +W + L ++ + +L EL ++N+ + ++ N+ G ++
Sbjct: 12951 PMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13010
Query: 1614 QEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE 1673
+V P +V ++ + + ++WE PPL+ +I Y + E R N +
Sbjct: 13011 LKVL----DKPGPPASVKINKMYSDRAMLSWE-PPLEDGGSEITNYIVDKRETSRPNWAQ 13065
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFN--AAGDGPRSTPTQGQTQQAAPSAPSSVK 1731
T+ + SV+ K + G+ Y + A N GD + P + P
Sbjct: 13066 VSATVPITSCSVE-KLIEGH-EYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 13123
Query: 1732 FSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD 1790
S +T + VSW+ P G + GY L V+ V+ K LK
Sbjct: 13124 ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VNRKPIIERTLKATG 13179
Query: 1791 LAEGVTYRFRIRAKTFTYGPEIEANVTTG----PGEGAPGPPGVPIIVRYS-SAIAIHWS 1845
L EG Y FR+ A GP ++ + + PGPP P + + S++++ W
Sbjct: 13180 LQEGTEYEFRVTAIN-KAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW- 13237
Query: 1846 SGDP---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
G P G PI Y++E + +D W + ++P+ + F + L Y FRV A
Sbjct: 13238 -GKPAYDGGSPIIGYLVEVKRADSDNW--VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYA 13294
Query: 1903 VNDYGFGTPSS-PSQSVP 1919
VN G+ PS P + P
Sbjct: 13295 VNKIGYSDPSDVPDKHYP 13312
Score = 211 bits (537), Expect = 6e-54
Identities = 342/1451 (23%), Positives = 555/1451 (38%), Gaps = 168/1451 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W K G + +I S L I D G YT + G + V +
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14100
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAP-WTVLLASVDPKA 647
P P PV +S V LTWT P DG SP+ YILE E + WTV+ S D ++
Sbjct: 14101 P-GPPGPVE-ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVV--SEDIQS 14156
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
L+ Y FR+ AVN GKG+ + + P PP+ S T +
Sbjct: 14157 CRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTA 14216
Query: 708 MIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKN-ITDADVNNLLLEDLIIWTNYEIE 766
+ W+ P + + I ++ R L K ++D L++ + YE
Sbjct: 14217 TVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQE---GSTYEFR 14273
Query: 767 VAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824
V+A N AG+G S ++ P PP N H T + W P +
Sbjct: 14274 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH------YD 14327
Query: 825 QGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG--FVSGLKKFTEYFTSVLCFTTPGDGPR 882
G ++ + E ++ + ++ + V L+ +Y + G G
Sbjct: 14328 GGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEP 14387
Query: 883 STPQLVRTHEDVPGPVGHLSFSEILDT-------SLKVSWQEPGEKNGILTGYRISWEEY 935
+ V E P L +E+ T S+++ G +T + +
Sbjct: 14388 AVIPDVEIVEREMAPDFELD-AELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK 14446
Query: 936 NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGP 995
NR N T + + T TIE A K G V+ + + PGP
Sbjct: 14447 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPA--GKKSGFVNVRVLDT------PGP 14498
Query: 996 PTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDAR 1054
NL ++I SVTL + P DG + I+ ++VE + + +
Sbjct: 14499 VLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS------YSTATTKCHKC 14552
Query: 1055 SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLW 1114
+ +V L+ Y FR+ N G P++ + ++ +AP P ++++ +++++
Sbjct: 14553 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSP--PDSLNIMDITKSTVS 14610
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
L W P+ +++G + GY I+ R T V+ + + +L E EY Q
Sbjct: 14611 LAW---PKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL---ECVVRNLTEGEEYTFQ 14664
Query: 1175 VQAFNAIG-SGPW-SQTVVGRTRESVPS---SGPTNVSALATTSSSMLVRWSEVPEADRN 1229
V A N+ G S P S+ V+ + + +P G +A ++ V E+P R
Sbjct: 14665 VMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV---EIPVLGRP 14721
Query: 1230 GLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFT------RIG 1283
+ +K K + V ++ ++ + + + V + T +G
Sbjct: 14722 KPTVTWK-----KGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVG 14776
Query: 1284 DGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342
D ++ + D+PGPP G I F EV + V W PP G+ ++ + T
Sbjct: 14777 D-------VITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 14829
Query: 1343 TTANTATVEVLAPSARQ-YTATGLKPESVYLFRITAQTRKGWGEA-AEALVVTTEKRDRP 1400
+ T VE+ R Y AT L Y FR+ AQ R G G A +V P
Sbjct: 14830 DS--TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVP 14887
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVSHNA 1458
PP P V V S+ +SW EP SDG SP+ Y ++ +E W + A V N
Sbjct: 14888 GPPGTPQVTA--VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 14945
Query: 1459 --SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTT 1515
SS + D + +Y+FRV A N G S+ S+ SE + L P P L++T HT
Sbjct: 14946 FKSSGLTDGI----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTV 15001
Query: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
T ++W P + G GF+I + + + P W + N
Sbjct: 15002 T---LKWAKP---EYTG---GFKIT----------SYIVEKRDLPNGRWLKA-------N 15035
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGPSSPPQEVFVGEAVPTAAPR----- 1628
S ++ + L + YE R+ NA G PS P + + V AP+
Sbjct: 15036 FSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDV 15093
Query: 1629 ----NVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
V++ A +L DV+ PPP + D + G +K +
Sbjct: 15094 KFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD--------GKELEGTAKLEIKIADFST 15145
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
N V K+ T + ++ A N G + + P P +V +E+T+ +
Sbjct: 15146 NLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAV--TEVTSEKCVL 15202
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLW-LKVKDLAEGVTYRFRI 1801
SW P G + +V + S++ +V + LKV L +G Y FR+
Sbjct: 15203 SWFPPLDDGGAKIDHYIVQKR-----ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRV 15257
Query: 1802 RA-KTFTYGPEIEANVTTGPGE-GAPGPPGVPIIVRYSS-AIAIHWSSGDP-GKGPITRY 1857
A + G +E+ G P PP P + + ++ + W D G I Y
Sbjct: 15258 MAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15317
Query: 1858 VIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
++E R W IK K ++ + + L G Y+FR++A N G PS S
Sbjct: 15318 IVERRDKAGQRW---IKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-- 15372
Query: 1918 VPAQKANPFYE 1928
PFY+
Sbjct: 15373 -------PFYK 15376
Score = 211 bits (537), Expect = 6e-54
Identities = 438/1934 (22%), Positives = 700/1934 (36%), Gaps = 355/1934 (18%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY----YVQAVNDKNGDNKTS 196
P P+VTW +D + + I T TL+I+ P+ RY +V + + G K S
Sbjct: 14432 PAPEVTWTKDNINLKNRANIENTESFTLLII----PECNRYDTGKFVMTIENPAG--KKS 14485
Query: 197 QPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKLHIIW 251
+ + V + GP + PT I T ++ G S +T +I+
Sbjct: 14486 GFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT------------NYIVE 14533
Query: 252 KKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFV 311
K++ S + TG G CE R + G EP V
Sbjct: 14534 KREATRKSYSTATTKCHKCTYKVTGLSEG---CEYFFRVMAENEYGIGEPTETTEP---V 14587
Query: 312 KEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLV 371
K E + ++DI S+ W K ++DGG +I+G V
Sbjct: 14588 KASEAPSPPDSLNIMDITKST-----VSLAWPK--------------PKHDGGSKITGYV 14628
Query: 372 PD-------------DTGMFQCFARN-AAGEVQTSTYLAVTS------------------ 399
+ +C RN GE T +AV S
Sbjct: 14629 IEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14688
Query: 400 IAPNI-TRGPLDSTVI--DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLE 456
+ P + RG VI G ++ + G P+P +TW+KG++IL Q F
Sbjct: 14689 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK--QTQRVNFETTA 14746
Query: 457 SGSLL-ISPTHISDAGTYTCLATNSRG----------------------VDEASADLVVW 493
+ ++L I+ SD+G Y A N G DE S+D V +
Sbjct: 14747 TSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 14806
Query: 494 ARTRITKPPQDQS-------VIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
+ PP++ V++ Q V V IR ++ T G E R+
Sbjct: 14807 S----WDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-IRTTYKATRLTTGLEYQFRV 14861
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
+ + T + + Y +V P P P T V +
Sbjct: 14862 KAQNRYGVGPGITSACIVANYPFKV------------------PGPPGTPQVT--AVTKD 14901
Query: 607 AINLTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFR 664
++ ++W +P DG SP++ Y +E E N W + ++ P GL +Y+FR
Sbjct: 14902 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP-GNIFKSSGLTDGIAYEFR 14960
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-L 723
+ A N GK + SK +E + + P PP + T ++ ++W P + G +
Sbjct: 14961 VIAENMAGKSKPSKPSEPMLALD--PIDPPGKPVPLNITRHTVTLKWAKP--EYTGGFKI 15016
Query: 724 KGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782
YI+ LP G K N ++ N + L YE V A N+AG
Sbjct: 15017 TSYIVE--KRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG-------- 15066
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
PP +E +++ T R AP + L A E + E
Sbjct: 15067 --------AISPP----SEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 15114
Query: 843 VTARPNFQDSIHVGFVSGLK----KFTEYFTSVL----------CFTTPGDGPRSTPQLV 888
P + S + G K ++ T+++ +T P + +
Sbjct: 15115 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHI 15174
Query: 889 RTHE--DVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTH 944
+ D PG P G L+ +E+ +SW P + G + Y + E +R
Sbjct: 15175 FNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA 15234
Query: 945 YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISN 1003
VT + +VT L Y V A+ G G+ + + + + P P PP N ++
Sbjct: 15235 SEVQVT-KLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTT 15293
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I S+ + + P DG + I ++VE + G+ W+ ++ D R +V L
Sbjct: 15294 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKA---GQRWIKCNK-KTLTDLR-YKVSGLT 15348
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPS---RKIQTLQAPPDMAPANVSLRTASETSLWLRW-M 1118
Y FR+ N G S PS S + T+ P P N + S +S+ + W
Sbjct: 15349 EGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG--PPGNPRVLDTSRSSISIAWNK 15406
Query: 1119 PLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAF 1178
P+ Y+G E GY ++ + + + YTI L E EY++++ A
Sbjct: 15407 PI----YDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAM 15462
Query: 1179 NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR---------------WSEV 1223
N+ G G +V T ++ P + A + +R EV
Sbjct: 15463 NSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEV 15520
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
A +G + + K T L+ GN +R GKY+L +
Sbjct: 15521 KWARDHG-----ESLDKASIESTSSYTLLIVGNVNRFDS----GKYIL---------TVE 15562
Query: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTT 1343
+ S S + + D PGPP + EV TSV L W PP G + I + +T
Sbjct: 15563 NSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 15622
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPP 1403
+TV + L+ Y FR+ A+ G G AE + + +RP PP
Sbjct: 15623 RKAYSTVATNCHKT-SWKVDQLQEGCSYYFRVLAENEYGIGLPAET-AESVKASERPLPP 15680
Query: 1404 SRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462
+ + DV SV LSWE P DG S + Y ++ + S +WA + +
Sbjct: 15681 GK--ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA---TCATVKVTEAT 15735
Query: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRW 1522
+ L Y FRV A N+ G S+ P LSV P ++I
Sbjct: 15736 ITGLIQGEEYSFRVSAQNEKGISD------------------PRQLSV-PVIAKDLVI-- 15774
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATW------AELTSM 1570
PPA F++ + + L G L+ G P TW + T+
Sbjct: 15775 -PPA----------FKLLFN--TFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTR 15821
Query: 1571 YSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV 1630
+ + SL + Y ++++ N+ GE + V PT V
Sbjct: 15822 VNAESTENNSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIVLDKPGPPTGP---V 15876
Query: 1631 VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNL 1690
+ TA + ++W PP D I Y + + T ++ + +A ++K L
Sbjct: 15877 KMDEVTADSITLSWGPPKYDG-GSSINNYIVE--KRDTSTTTWQIVSATVARTTIKACRL 15933
Query: 1691 TGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
Y +AA N G S PT Q P P + + + S+ V W
Sbjct: 15934 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWN--- 15990
Query: 1749 FPNGILEGYRLVYEPCSPVDGVSKIVTVDV---KGNSPLWLKVK------------DLAE 1793
EP S DG S+++ + + NS LW+K+ L E
Sbjct: 15991 -------------EPIS--DGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 16035
Query: 1794 GVTYRFRIRAKTFT----YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD- 1848
GV Y FR+ A+ E V P + PG P I+ R +++ + W
Sbjct: 16036 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCD-PPGRPEAIIVTR--NSVTLQWKKPTY 16092
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG- 1907
G IT Y++E + EG W +K + F + L Y+FRVIA N G
Sbjct: 16093 DGGSKITGYIVEKKELPEGRW---MKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 16149
Query: 1908 FGTPSSPSQSVPAQ 1921
F PS + ++ A+
Sbjct: 16150 FSEPSESTGAITAR 16163
Score = 210 bits (535), Expect = 1e-53
Identities = 345/1488 (23%), Positives = 556/1488 (37%), Gaps = 155/1488 (10%)
Query: 506 SVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LDRNGSLHISQTWSGDI 564
+V GT+ + VT P I W K L + I + + ++ I + D
Sbjct: 7329 TVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7386
Query: 565 GTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLI 623
GTY ++ G + + V P P ++ V + LTW P D G S +
Sbjct: 7387 GTYIIEAVNVCGRATAVVEVNVLDKPGPPA--AFDITDVTNESCLLTWNPPRDDGGSKIT 7444
Query: 624 RYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
Y++E ++ W L ++V K T+ L+P + Y FR+ A N G G+ + +
Sbjct: 7445 NYVVERRATDSEVWHKLSSTV--KDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 7502
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
+ + P PP + S T ++ + W P + + I GY + +
Sbjct: 7503 TAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT-GYWVERLDPDTDKWVRCN 7561
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHA 800
+ D ++ L Y V A N AG G S ++ P PPG
Sbjct: 7562 KMPVKDTT-YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTV 7620
Query: 801 EATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ T++R W P I + Y + + +E V + P Q + G
Sbjct: 7621 KDVGKTSVRLNWTKPEHDGGAKI-ESYVIEMLKTGTDEWVRVAEGVPTTQH-----LLPG 7674
Query: 861 LKKFTEYFTSVLCFTTPGDGPRSTPQ---LVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G+ S P L R P P L I + + W
Sbjct: 7675 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 7734
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +T Y + + R + T + VT LT + Y VAA + GQ
Sbjct: 7735 PEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDT-KCTVTPLTEGSLYVFRVAAENAIGQ 7793
Query: 977 GQVSA--STISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVG 1033
+ ++ + PGPP L + ++ R V L++ P DG I R+++E +
Sbjct: 7794 SDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKER 7853
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
+ G W+ + + PD + V D+ T F++R N G PS+P+ +I +++
Sbjct: 7854 L---GTRWVKAGKTAG-PDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT-EILSIE 7907
Query: 1094 AP--PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKI--------KYSRSDG 1143
P P P ++ + A + + W P E NG +GY + K+ R +
Sbjct: 7908 DPTSPPSPPLDLHVTDAGRKHIAIAWKP---PEKNGGSPIIGYHVEMCPVGTEKWMRVNS 7964
Query: 1144 HG-KTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG---SGPWSQTVVGRTRESVP 1199
K L V++ V D EY ++V+A NAIG S+ VV + + P
Sbjct: 7965 RPIKDLKFKVEEGVVPD---------KEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKP 8015
Query: 1200 SSG--PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
+ ++ + S+ V + VP V +K + K SD L N
Sbjct: 8016 TIDLETHDIIVIEGEKLSIPVPFRAVPVPT----VSWHKDGKEVKASDR-----LTMKND 8066
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFT---RIGDGSPSHPPILERTLDDVPGPPMGILFPEVRT 1314
SA L + K V + + T ++G + S + + +PGP I ++
Sbjct: 8067 HISAHLE-VPKSVRADAGIYTITLENKLGSATAS----INVKVIGLPGPCKDIKASDITK 8121
Query: 1315 TSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFR 1374
+S +L W+PP G + + + R V + + +T L P Y FR
Sbjct: 8122 SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFR 8180
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSWEPGS-DGLSPV 1432
+ A + G GE E L +D QPP P+ V+ + A ++ ++W+P DG S +
Sbjct: 8181 VKAVNKVGGGEYIE-LKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8239
Query: 1433 RYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE 1492
Y I+ RW + + ++ L+ Y+FRV+A N G SE S +
Sbjct: 8240 MGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATP 8298
Query: 1493 SLTTLQAAPDEAPTIL-------------------SVTPHTTTSVLIRWQP------PAE 1527
T P +AP ++ S +P+ T I W P E
Sbjct: 8299 P--TKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPT----ITWIKDENVIVPEE 8352
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
K L +R R+ + F L LT S+ N + D
Sbjct: 8353 IKKRAAPL---VRRRKGEVQEEEPFVL-----------PLTQRLSIDNSKKGESQLRVRD 8398
Query: 1588 NLNK-HRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEP 1646
+L H Y I++ + + + P + V P N V T + WEP
Sbjct: 8399 SLRPDHGLYMIKVENDHGIAKAPCT------VSVLDTPGPPINFVFEDIRKTSVLCKWEP 8452
Query: 1647 PPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAA 1706
P LD +I Y + + + + V T L + L Y+ V A N
Sbjct: 8453 P-LDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8511
Query: 1707 GDGPR--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
G GP S P + P AP ++T+ S+ V W P+ + GY L
Sbjct: 8512 GPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREV 8571
Query: 1765 SPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTT 1818
+ V+K + +K N V L EG+TY FR+ A+ + P +
Sbjct: 8572 NSTHWSRVNKSLLNALKAN------VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAH 8625
Query: 1819 GPGEGAPGPPGVPIIVRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIP 1877
P PGPP + S+ I + W G G I Y ++ + W + +
Sbjct: 8626 DP-ISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI 8684
Query: 1878 KEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
K V YT ++ G Y RV AVN G G P A+ P
Sbjct: 8685 K-VRQYTVKE--IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP 8729
Score = 207 bits (527), Expect = 9e-53
Identities = 337/1448 (23%), Positives = 550/1448 (37%), Gaps = 155/1448 (10%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGGNDSRS 581
P+ T+ W KDG TL + + + SL I + D+GTY V ++ G+ +
Sbjct: 19050 PQATVN--WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 19107
Query: 582 AHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVL 639
+ V P P P+ + V +I ++W P +DG + YI+E E + W ++
Sbjct: 19108 ITIIVLDRP-GPPGPIR-IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19165
Query: 640 LASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIA 699
+V TS+ + L YQFR+CA N GK +S+ + V+ P PP
Sbjct: 19166 SQAV--ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV 19223
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
T ++++ WQ P + ++ GY + Y + + I AD + + L
Sbjct: 19224 VHATKSTMLVTWQVPVNDGGSRVI-GYHLEYKERSSILWSKANKILIADTQ-MKVSGLDE 19281
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
YE V A N AG+G SK E P PPG ++ W+ P
Sbjct: 19282 GLMYEYRVYAENIAGIGK-CSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPH--- 19337
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEY----FTSVLCF 874
+ G K+ + E+ E + N+ + F V+ L + Y F
Sbjct: 19338 ---YDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAAD 19394
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS----LKVSWQEPGEKNGILTGYRI 930
+ + P +V+ + P + + F +++ LK++ G +++ +
Sbjct: 19395 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19454
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPP 990
E R T + + L + Y + + + V+ +
Sbjct: 19455 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK---- 19510
Query: 991 ELPGPPTN-LGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP L I+ + +L + RP DG I ++VE + W +
Sbjct: 19511 --PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET---SHLAWTICE--- 19562
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP--SQPSRKIQTLQAPPDMAPANVSLR 1106
E S +V L Y FR+ VN G P S + + P P ++ +
Sbjct: 19563 GELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEIT 19620
Query: 1107 TASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV-VQDRVERDYTIED- 1164
+ ++ S+ L W E +G E GY I+ + +L V V + D ++
Sbjct: 19621 SVTKESMTLCWS---RPESDGGSEISGYIIERREKN----SLRWVRVNKKPVYDLRVKST 19673
Query: 1165 -LEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESV----PSSGPTNVSALATTSSSMLV 1218
L E EY +V A NA G S P + + R + V P S P V + TT + +
Sbjct: 19674 GLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTT---ITI 19730
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLT--GLGKYVLYEVQV 1276
W + P D + GY V YK+ D DT W S R + T GL Y +V
Sbjct: 19731 AWVK-PLFDGGAPITGYTVEYKKSD-DTD---WKTSIQSLRGTEYTISGLTTGAEYVFRV 19785
Query: 1277 LAFTRIGDGSPSH---PPILERTLDDVPGPPMGILFPEVRTTSV---RLIWQPPAAPNGI 1330
+ ++G PS P I + ++ P+ + E+R T + + G
Sbjct: 19786 KSVNKVGASDPSDSSDPQIAKEREEE----PLFDIDSEMRKTLIVKAGASFTMTVPFRGR 19841
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ + + +T A V+ S T + +T Q +A +L
Sbjct: 19842 PVPNVLWSKPDTDLRTRAYVDT-TDSRTSLTIENANRNDSGKYTLTIQNVL----SAASL 19896
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWAL 1449
+ + D P PP+ VQ DV S +LSW+ P +DG +PV+ Y I+ RE W
Sbjct: 19897 TLVVKVLDTPGPPTNITVQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWV- 19953
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
S + + N S+ V L+ Y FRV N+ G +E E + + P L
Sbjct: 19954 -SVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKP--SPPEKLG 20010
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + SV + W P D G RI + + + + W +
Sbjct: 20011 VTSISKDSVSLTWLKPEHDG------GSRIVH----------YVVEALEKGQKNWVKCAV 20054
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------P 1623
S T + + L ++ Y R+ N G S P+E+ + + P
Sbjct: 20055 AKS---------THHVVSGLRENSEYFFRVFAENQAG---LSDPRELLLPVLIKEQLEPP 20102
Query: 1624 TAAPRN-----VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
+N V V + ++D+ PL G + T R T
Sbjct: 20103 EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL--------KATMRFNTE 20154
Query: 1679 FLAEN-SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737
AEN ++ LK A + A N++G + P+ P V S++T
Sbjct: 20155 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP--VVISDITE 20212
Query: 1738 TSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVT 1796
SV + WE P++ G + Y L+ S TV + +KV L G
Sbjct: 20213 ESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV-----ARTMMKVMKLTTGEE 20267
Query: 1797 YRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKG 1852
Y+FRI+A+ F I+ A VT PGPP P + + +I + W G
Sbjct: 20268 YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGS 20327
Query: 1853 PITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ Y +E + + LW K + + + F + + G+ Y+FRV A N G G PS
Sbjct: 20328 AVVGYHLEMKDRNSILWQKANKLV---IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPS 20384
Query: 1913 SPSQSVPA 1920
PS+ V A
Sbjct: 20385 HPSEPVLA 20392
Score = 207 bits (526), Expect = 1e-52
Identities = 333/1443 (23%), Positives = 538/1443 (37%), Gaps = 164/1443 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W DG+ + T+ H + D S L I D G Y V +A G+ + + HL V +
Sbjct: 11172 WTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDV 11231
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P+ L + ++W P D G SP+I YI+E + +++S K T
Sbjct: 11232 PGPPTGPINILDVTPEH-MTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 11289
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ + L Y FR+ A N +G G T V+ + P +PP + + T +
Sbjct: 11290 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT 11349
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVA 768
+ W P + I Y+ R + G V I D + L YE V
Sbjct: 11350 VSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADL---KFRVTGLYEGNTYEFRVF 11406
Query: 769 AYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG 826
A N AGL SS + P PP N + + T W P + G
Sbjct: 11407 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS------DGG 11460
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIH--VGFVSGLKKFTEYFTSVLCFTTPGDG-PRS 883
++ + E ++ T R N + I V GL + EY + G+G PR
Sbjct: 11461 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11520
Query: 884 TPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYR------ISWEEYNR 937
+ V + + H E+ T V G+ IL + I+W + +
Sbjct: 11521 LAESV-----IAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11575
Query: 938 TNTR-----VTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
R + LP V L+ + Y I + QG + + +
Sbjct: 11576 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVL------DR 11629
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
PGP NL ++N+ + T+ + P +G + I+ ++VE + + W ++ +++
Sbjct: 11630 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR---KPNQKGWSIV---ASDV 11683
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQ---PSRKIQTLQAPPDMAPANVSLRTA 1108
R ++ +L Y FR+ N VG P + P I + P + P N+ +
Sbjct: 11684 TKRLIKA-NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGE--PENLHIADK 11740
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLE 1166
+T ++L+W +Y+G ++ Y + + SD + ++ E Y ++
Sbjct: 11741 GKTFVYLKWR---RPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK---ETHYMVDRCV 11794
Query: 1167 EWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS-------SGPTNVSALATTSSSMLVR 1219
E Y +VQ N G W +T +E + SG V A T VR
Sbjct: 11795 ENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVR 11854
Query: 1220 WSEVPEA----DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQ 1275
PE D++ L K +F L + S GKYV
Sbjct: 11855 GKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDG------GKYV----- 11903
Query: 1276 VLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ 1335
V A G S + D PGP + +V + + W PP G +
Sbjct: 11904 VTATNTAG----SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 11959
Query: 1336 ITHRLNTTTA--NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VV 1392
I + T +T + VL P T T L + Y+FR+ A+ + G G E+ V+
Sbjct: 11960 ILEKCETKRMVWSTYSATVLTPGT---TVTRLIEGNEYIFRVRAENKIGTGPPTESKPVI 12016
Query: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWA-LH 1450
K D+P P P V + V + + W P DG + Y ++ +E S RW ++
Sbjct: 12017 AKTKYDKPGRPDPPEVTK--VSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN 12074
Query: 1451 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ-AAPDEAPTILS 1509
+++ V L P Y+FRVKA N+IG E S S + P PT
Sbjct: 12075 KSAIPERRMK--VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFR 12132
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
V T S+ + W P D ++G+ + R + + +P W +
Sbjct: 12133 VVDTTKHSITLGWGKPVYDG-GAPIIGYVVEMRPKIADA----------SPDEGWKRCNA 12181
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG------PSSPPQEVFVGEAVP 1623
+ ++ + +L++++ YE R+ N VG G + P+E+ +
Sbjct: 12182 AAQLVR------KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEID 12235
Query: 1624 TAAP--RNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL- 1678
A + V+V +L V P P + K+ R + V T+
Sbjct: 12236 LDASMRKLVIVRAGCPIRLFAIVRGRPAP------KVTWRKVGIDNVVRKGQVDLVDTMA 12289
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
FL + + Y+ +V+ A A R T P S +K S++T T
Sbjct: 12290 FLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDT--------PGPVSDLKVSDVTKT 12341
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYR 1798
S +VSW P+ G + +V E VT +VK S V +L G Y
Sbjct: 12342 SCHVSWAPPENDGGSQVTHYIV-EKREADRKTWSTVTPEVKKTS---FHVTNLVPGNEYY 12397
Query: 1799 FRIRAKTFTYGPEIEANV-----TTGPGEGAPGPPGVPIIVRYSSAIAIHW-----SSGD 1848
FR+ A YGP + +V + P P + + ++ + W G
Sbjct: 12398 FRVTAVN-EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGA 12456
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGF 1908
G IT Y E +P+D ++KD+ V+ LK G Y FRV A N G
Sbjct: 12457 KIDGYITSYREEEQPADRWTEYSVVKDLSLVVTG-------LKEGKKYKFRVAARNAVGV 12509
Query: 1909 GTP 1911
P
Sbjct: 12510 SLP 12512
Score = 204 bits (520), Expect = 6e-52
Identities = 375/1638 (22%), Positives = 639/1638 (39%), Gaps = 191/1638 (11%)
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAG---EVQTSTYLAVTS----IAPNITRGP--LDST 412
D +++GLV D F+ ARNAAG E ST A+T+ P I+ P D+
Sbjct: 16123 DTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTG-AITARDEVDPPRISMDPKYKDTI 16181
Query: 413 VID-GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
V+ G S + + G P P I W KG++ L S + +L + + SL + D+G
Sbjct: 16182 VVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAVRVDSG 16240
Query: 472 TYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQA---------------SMV 516
Y A N G + ++ V R PP+ VI G A S +
Sbjct: 16241 NYILKAKNVAGERSVTVNVKVLDR---PGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDI 16297
Query: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG- 575
+ R T R +W A + T S +++ G+ YT R+++
Sbjct: 16298 INYIVERRETSRLVWTVVDANVQTL-----------SCKVTKLLEGN--EYTFRIMAVNK 16344
Query: 576 ---GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILE 628
G S + + +P AP+ P T TV + ++ + W +P DG S ++ Y+LE
Sbjct: 16345 YGVGEPLESEPVVAKNPFVVPDAPKAPEVT--TVTKDSMIVVWERPASDGGSEILGYVLE 16402
Query: 629 MSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT--ERVSL 685
+ WT + + + V GL+ Y+FR+ A N G + S + ++
Sbjct: 16403 KRDKEGIRWTRCHKRLIGE-LRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 16461
Query: 686 PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
P P PP N T S+ + W P + G ++GYI+ C +
Sbjct: 16462 PIYKP-GPPNNPKVIDITRSSVFLSWSKP--IYDGGCEIQGYIVEKCDVSVGEWTMCTPP 16518
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T + N+ +E L+ Y + A N AG+G ++ ++ P ++ E
Sbjct: 16519 TGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRK 16578
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLK 862
IR F+ + + W E + ++ +F + L
Sbjct: 16579 IINIRA--GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV-------LD 16629
Query: 863 KFTEYFTSVLCFTTP-GDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEK 921
Y + T G +S VR D P P +L +EI S+ ++W+ P
Sbjct: 16630 NVNRYDSGKYTLTLENSSGTKSAFVTVRV-LDTPSPPVNLKVTEITKDSVSITWEPPLLD 16688
Query: 922 NGI-LTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ 978
G + Y + E R + VT+ N +++ L +Y V A G G
Sbjct: 16689 GGSKIKNYIVEKREATRKSYAAVVTNCHKN---SWKIDQLQEGCSYYFRVTAENEYGIG- 16744
Query: 979 VSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+ A T E+P PP + + ++ SV+L + +P +DG + I +++VE Q
Sbjct: 16745 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ---AKH 16801
Query: 1038 GEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQ 1093
E+W S +S++ + +L Y FR+ VN G S P + I + L
Sbjct: 16802 SEKW------SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV 16855
Query: 1094 APPDMAPA--NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV 1151
PD+ PA + S++ + + E+ +G P+ I +++ K + +
Sbjct: 16856 IEPDVKPAFSSYSVQVGQDLKI--------EVPISGRPKPT---ITWTKDGLPLKQTTRI 16904
Query: 1152 -VQDRVE-RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
V D ++ +I++ + + + N +G S +V + P GP +
Sbjct: 16905 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD-PPKGPVKFDDV 16963
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW-LVEGNSSRSA-QLTGLG 1267
++ S+ + W+ P G + ++ K DT W +V +R+ ++T L
Sbjct: 16964 --SAESITLSWN--PPLYTGGCQITNYIVQKR---DTTTTVWDVVSATVARTTLKVTKLK 17016
Query: 1268 KYVLYEVQVLAFTRIGDG-SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAA 1326
Y+ ++ A R G + PI+ + PGPP + S+ + W P
Sbjct: 17017 TGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVN 17076
Query: 1327 PNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGE 1385
G ++ Y + + + T + + Q+ A L+ Y FR+ A+ G G+
Sbjct: 17077 NGGSPVIGYHLERKERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGK 17135
Query: 1386 AAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTREL 1442
A++ V + D P P MV++ + + L W +P DG S + Y ++ R+L
Sbjct: 17136 ASKNSECYVARDPCDPPGTPEPIMVKRNE-----ITLQWTKPVYDGGSMITGYIVEKRDL 17190
Query: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
P GRW + ++ + + F V L Y+FRV A N G S+ S+S + A +
Sbjct: 17191 PDGRW-MKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG--AISKPSDSTGPITAKDE 17247
Query: 1503 EAPTILSVTPHTTTSVLIRWQPP--AEDKINGILLGFRIRYRELLYEGLRG-FTLRGINN 1559
+S+ P ++++ E ++G L E LRG +
Sbjct: 17248 VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP--------TIEWLRGDKEIEESAR 17299
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYEL--DNLNKHRRYEIRMSVYNAVG--EGPSSPPQE 1615
+ ++ +++ R QY L N+ + + + + V + G EGP
Sbjct: 17300 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP------ 17353
Query: 1616 VFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERV 1675
V V G T+ + +TW PPL DI Y + E R L V
Sbjct: 17354 --------------VQVTGVTSEKCSLTWS-PPLQDGGSDISHYVVEKRETSR--LAWTV 17396
Query: 1676 KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFS 1733
+ NS+K+ L Y+ + A N G G S P + P P S++ +
Sbjct: 17397 VASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 17456
Query: 1734 ELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLA 1792
+ S+ V W P G + GY + S + + + + + + L L+V L
Sbjct: 17457 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGI----RWIKCNKRRITDLRLRVTGLT 17512
Query: 1793 EGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPP-GVPIIVRYSSAIAIHWSSGD 1848
E Y FR+ A+ G A V + PGPP I+ ++I + W G
Sbjct: 17513 EDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW--GK 17570
Query: 1849 P---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
P G I YV+E +DE W I+ V+ + S L Y RV A+N
Sbjct: 17571 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISK--LTEHQEYKIRVCALNK 17628
Query: 1906 YGFGTPSS-PSQSVPAQK 1922
G G +S P P K
Sbjct: 17629 VGLGEATSVPGTVKPEDK 17646
Score = 202 bits (515), Expect = 2e-51
Identities = 431/1978 (21%), Positives = 725/1978 (36%), Gaps = 286/1978 (14%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGAL----------LQRQTEVQ--VAYMGSFEEGEK 120
E +Y +T L +R I RN +G + + R V V + + +G
Sbjct: 21538 ECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDG-- 21595
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT--LENTLVILSTVAPDA 178
+ GE+ I+A + P P+VTWF+DG +I + IT L +T + + D
Sbjct: 21596 -LIIKSGESLRIKA-LVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDH 21653
Query: 179 GRYYVQAVNDKNGDNKTSQPITL--TVENVGGPA-------------------DPIAPTI 217
Y + +G K + + T V GP D AP
Sbjct: 21654 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 21713
Query: 218 --IIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPT 275
II + TS +A + +C A + IKL +G +S N+ + P
Sbjct: 21714 HYIIEKRETSRLAWAL-IEDKCEAQSYTAIKLI-----NGNEYQFRVSAVNK-FGVGRPL 21766
Query: 276 GSDAGYYECEAVLRSSS---VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQA 332
SD + + + + PS + G +++ PE +E+++ + +
Sbjct: 21767 DSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA-----RPESDGGSEIQQYILERREK 21821
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
K S W K + + + TRF+ ++GL + F A NAAG S
Sbjct: 21822 K-----STRWVKVISKRPISE-TRFK--------VTGLTEGNEYEFHVMAENAAGVGPAS 21867
Query: 393 ------------------TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
T + VT + V DG ++
Sbjct: 21868 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21927
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGV-DEASADLVVW 493
W K + A V+ R+T ++ + + A N G D +
Sbjct: 21928 WHK---VNAEACVKT-RYT--------VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIK 21975
Query: 494 ARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR 547
A R+T P D Q+ + AS+ + + R T +W K + L +
Sbjct: 21976 AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT 22035
Query: 548 LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRA 607
D +L + D G YT V + G+ S + ++V P P P+ T V R +
Sbjct: 22036 -DSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTP-GPPGPI-TFKDVTRGS 22092
Query: 608 INLTWTKPF-DGNSPLIRYILEMSE-NNAPWTVLLASVDPKATS--VTVKGLVPARSYQF 663
L W P DG + + Y++E E + W V + K T V L Y F
Sbjct: 22093 ATLMWDAPLLDGGARIHHYVVEKREASRRSWQV----ISEKCTRQIFKVNDLAEGVPYYF 22148
Query: 664 RLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI- 722
R+ AVN+ G G+ + E + E+P APP+ + + S ++ W P H G
Sbjct: 22149 RVSAVNEYGVGEPYEMPEPIVATEQP--APPRRLDVVDTSKSSAVLAWLKP--DHDGGSR 22204
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG----VY 778
+ GY++ G + + +E L+ T YE V A N AG +
Sbjct: 22205 ITGYLLEMRQKGSDFWVEAGHTKQL---TFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 22261
Query: 779 SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG-------YKLIA 831
SS + + P + P A+ T T T A SP I+ G +KL
Sbjct: 22262 SSVIIK-----EPQIEPT---ADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEE 22313
Query: 832 WEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH 891
++ + V++ T + ++ + YF ++ T G S +V
Sbjct: 22314 MRLKETDRVSITTTKDRTTLTVKDSMRGDSGR---YFLTLE--NTAGVKTFSVTVVVIGR 22368
Query: 892 EDVPGPV-GHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNV 949
PGPV G + S + S +SW EP + G +T Y + E T ++ +
Sbjct: 22369 ---PGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKR 22425
Query: 950 TLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNIGPRS 1008
T + +VT LT Y+ V++ G + + ++ I + P P PT + ++ +
Sbjct: 22426 T-QIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANA 22484
Query: 1009 VTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
+++++ P +DG + I + VE + E L + + + +V L Y
Sbjct: 22485 MSIRWEEPYHDGGSKIIGYWVEKK-----ERNTILWVKENKVPCLECNYKVTGLVEGLEY 22539
Query: 1068 SFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
FR +N G S S+ SR I Q P D AP + + +++ L W Y+G
Sbjct: 22540 QFRTYALNAAGVSKASEASRPIMA-QNPVD-APGRPEVTDVTRSTVSLIWSA---PAYDG 22594
Query: 1128 NPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGP 1185
+ VGY I K G G+ L + +T+ L E Y +V A NA G
Sbjct: 22595 GSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG--- 22651
Query: 1186 WSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD 1245
V+ + ES + A + V + LVL V K
Sbjct: 22652 ----VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKP---- 22703
Query: 1246 TQPRFWLVEGNSSR------SAQLTGL--------------GKYVLYEVQVLAFTRIGDG 1285
+P+ +G+ S Q TG GKY L +
Sbjct: 22704 -EPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS-- 22760
Query: 1286 SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTA 1345
++ + LD PGP + V L W P G + + I R T+
Sbjct: 22761 ------VMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 22813
Query: 1346 NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEKRDRPQPPS 1404
N VE P+ Y T L + Y+FR+ A + G G E+ +V P PP
Sbjct: 22814 NWVIVEGECPTL-SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPG 22872
Query: 1405 RPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
P ++ +++ W +P SDG + + Y + RE S RW + + V
Sbjct: 22873 IP--EEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKV 22930
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVTPHTTTSVL 1519
L Y+FRV A N G+SE SE S ++ + + P AP ++ T H S+
Sbjct: 22931 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKH---SIS 22987
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
+ W P D I+ G+ L W + + ++RN
Sbjct: 22988 LAWTKPMYDGGTDIV----------------GYVLEMQEKDTDQWYRVHTNATIRN---- 23027
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSS-------PPQEVFVGE-AVPTAAPRNVV 1631
T++ + +L ++Y R++ N G S P + + + + + + V
Sbjct: 23028 --TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVT 23085
Query: 1632 VHGATATQL--DVTWEPPPL---DSQNGDIQGYKIY-FWEAQRGNLTERVKTLFLAENSV 1685
+ + +L V+ PPP+ Q D+ I E+ + ++V + ++
Sbjct: 23086 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTI 23145
Query: 1686 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
+ +N +G + V V ++ G P SVK E++ SV ++WE
Sbjct: 23146 EAENQSGKKSATVLVKVYDTPGPCP------------------SVKVKEVSRDSVTITWE 23187
Query: 1746 APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1805
P G +V + + + TV K + L+ ++ L EG Y FR+ +
Sbjct: 23188 IPTIDGGAPVNNYIVEKREA---AMRAFKTVTTKCSKTLY-RISGLVEGTMYYFRVLPEN 23243
Query: 1806 -FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARP 1863
+ G E + E P + ++ S + + W G +T YV+EA
Sbjct: 23244 IYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK 23303
Query: 1864 SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
+ W +K + + + ++ L G Y FR+ A N+ G P +V Q
Sbjct: 23304 AGTERW---MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 23358
Score = 201 bits (512), Expect = 5e-51
Identities = 369/1646 (22%), Positives = 603/1646 (36%), Gaps = 237/1646 (14%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVIDGMS----- 418
++ LV F+ A+N AG + + T I + P LD T+ DG++
Sbjct: 13963 VTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGD 14022
Query: 419 --VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ A G P P +W K + + + TP S L I DAG YT
Sbjct: 14023 TIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSS-MLTIKYATRKDAGEYTIT 14081
Query: 477 ATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVTHDPRV 525
ATN G + V I+ +++ + T S + + R
Sbjct: 14082 ATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRE 14141
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRS 581
T R +W + + H +L + Y RV + G +S
Sbjct: 14142 TSRLLWTVVSEDIQSCRHVATKLIQGNE-------------YIFRVSAVNHYGKGEPVQS 14188
Query: 582 AHLRVRQL---PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWT 637
+++ P PE P +S V + ++W +P D G S + Y +E E +
Sbjct: 14189 EPVKMVDRFGPPGPPEKP--EVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRW 14246
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQN 696
V V GL +Y+FR+ A N G G S+ ++ V + + P PP N
Sbjct: 14247 VRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 14306
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILK--GYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
+ T +S + W P H +G L+ GY++ + G + T + ++
Sbjct: 14307 PHVTDTTKKSASLAWGKP---HYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVV 14363
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
DL Y ++A N AG+G + + + + P + AE + +R
Sbjct: 14364 PDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVEREMAPDFELDAELRRTLVVR----- 14417
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
G + + P + VT +D+I++ + ++ TE FT ++
Sbjct: 14418 ----------AGLSIRIFVPIKGRPAPEVTWT---KDNINLKNRANIEN-TESFTLLII- 14462
Query: 875 TTPGDGPRSTPQLVRTHE---------------DVPGPVGHLSFSEILDTSLKVSWQEPG 919
P T + V T E D PGPV +L ++I S+ + W P
Sbjct: 14463 --PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14520
Query: 920 EKNGI-LTGYRISWEEYNR----TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
G +T Y + E R T T H Y+VTGL+ Y V A
Sbjct: 14521 IDGGSRITNYIVEKREATRKSYSTATTKCH-----KCTYKVTGLSEGCEYFFRVMAENEY 14575
Query: 975 GQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVG 1033
G G+ + +T E P PP +L I +I +V+L + +P +DG + I+ +++EAQ
Sbjct: 14576 GIGEPTETT-EPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRK 14634
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
++W I + V +L Y+F++ VN G S
Sbjct: 14635 ---GSDQWTHITTVKG----LECVVRNLTEGEEYTFQVMAVNSAGRS------------- 14674
Query: 1094 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESV-------GYKIKYSRSDGHGK 1146
AP + P V +T LPE++ G + + K++
Sbjct: 14675 APRESRPVIVKEQTM-----------LPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKP 14723
Query: 1147 TLSHVVQDRVERDYTIEDLEEW-TEYRVQVQAFNAIGSGPWSQT---VVGRTRESV---- 1198
T++ D++ + + E T + + SGP+ T +VG + +
Sbjct: 14724 TVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQV 14783
Query: 1199 -----PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV 1253
P +GP ++ S + W + PE D + Y V ++ DS T
Sbjct: 14784 HDIPGPPTGPIKFDEVS--SDFVTFSW-DPPENDGGVPISNYVVEMRQTDSTTWVELATT 14840
Query: 1254 EGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEV 1312
++ A T L + Y+ +V A R G G + I+ VPGPP V
Sbjct: 14841 VIRTTYKA--TRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAV 14898
Query: 1313 RTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY 1371
S+ + W P + G IL Y + + + L P + ++GL Y
Sbjct: 14899 TKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPG-NIFKSSGLTDGIAY 14957
Query: 1372 LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE-----------DVRARSVLL 1420
FR+ A+ G + +P PS PM+ + ++ +V L
Sbjct: 14958 EFRVIAENMAG--------------KSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTL 15003
Query: 1421 SW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKAT 1479
W +P G + Y ++ R+LP+GRW + S + + F V L +Y+FRV A
Sbjct: 15004 KWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFS-NILENEFTVSGLTEDAAYEFRVIAK 15062
Query: 1480 NDIGD-SEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFR 1538
N G S SE S+++T EAP I T +L + FR
Sbjct: 15063 NAAGAISPPSEPSDAITCRDDV--EAPKIKVDVKFKDTVILKAGE------------AFR 15108
Query: 1539 IRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIR 1598
+ + G P W++ + + + +NK
Sbjct: 15109 LEA-----------DVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRR-D 15156
Query: 1599 MSVYNAVGEGPSSPPQEVFVGEAVPTAAPRN--VVVHGATATQLDVTWEPPPLDSQNGDI 1656
Y P + +F + + P + V T+ + ++W PP LD I
Sbjct: 15157 SGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPP-LDDGGAKI 15215
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
Y + E R T + + + +K+ L Y+ V A N G G S P
Sbjct: 15216 DHYIVQKRETSRLAWTNVASEVQVTK--LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 15273
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIV 1774
P P + + + +T S+ V W P G E + E + +
Sbjct: 15274 VLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS-EIINYIVERRDKAG--QRWI 15330
Query: 1775 TVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGA------PGPP 1828
+ K + L KV L EG Y FRI A+ I A T P A PGPP
Sbjct: 15331 KCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN---AAGISAPSPTSPFYKACDTVFKPGPP 15387
Query: 1829 GVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 1886
G P ++ S S+I+I W+ G IT Y++E +E W I+ + +SYT +
Sbjct: 15388 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 15447
Query: 1887 MDILKPGVSYDFRVIAVNDYGFGTPS 1912
L Y R+ A+N G G P+
Sbjct: 15448 G--LTENQEYKIRIYAMNSEGLGEPA 15471
Score = 201 bits (510), Expect = 8e-51
Identities = 370/1602 (23%), Positives = 611/1602 (38%), Gaps = 215/1602 (13%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G +V L G P P ++W+K +L + +L + + D+G
Sbjct: 12934 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLCTLELFSVNRKDSG 12992
Query: 472 TYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVT 520
YT A NS G A+ L V A +I K D++++ S +
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052
Query: 521 HDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
D R T R W + AT+ S +L C G D
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFR----------ICAENKYGVGDPV 13102
Query: 581 SAHLRVRQLPHAP----EHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP 635
+ + P+ P + PV +S + + + ++W P D G SP+ Y+LE E A
Sbjct: 13103 FTEPAIAKNPYDPPGRCDPPV--ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAV 13160
Query: 636 -WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP--PTA 692
WT + + T + GL Y+FR+ A+N G G+ S D + + +P P
Sbjct: 13161 NWTKVNRKPIIERT-LKATGLQEGTEYEFRVTAINKAGPGKPS-DASKAAYARDPQYPPG 13218
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIR--------YCLAGLPVGYQFKNI 744
PP T S+ + W P + I+ GY++ + LP Q
Sbjct: 13219 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPII-GYLVEVKRADSDNWVRCNLPQNLQK--- 13274
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T +V L+ ED T Y+ V A N G S + + + P G + A+
Sbjct: 13275 TRFEVTGLM-ED----TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 13329
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT-ARPNFQDSIHVGFVSGLKK 863
+ +R G + + P + +T ++PN +G K
Sbjct: 13330 TLILR---------------AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDI---K 13371
Query: 864 FTEYFTSVLC------------FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
T++ T + C T + +V D PGP +++ EI S
Sbjct: 13372 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13431
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
V+W+ P G + Y + + R + + T +RV L +Y V A
Sbjct: 13432 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT-SFRVANLEEGKSYFFRVFA 13490
Query: 971 MTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVE 1029
G G T + + PGP +L + ++ S ++ ++ P DG + I ++V+
Sbjct: 13491 ENEYGIGD-PGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 13549
Query: 1030 AQVGVVGEGEEWL-LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
+ E +W ++ LS + A+ DL Y+FR+ N G PS+
Sbjct: 13550 ----FLTEENKWQRVMKSLSLQYSAK-----DLTEGKEYTFRVSAENENGEGTPSEI--- 13597
Query: 1089 IQTLQAPPDMAPANVSLR-------TASETSLW-----LRWMPLPEMEYNGNPESVGYKI 1136
T+ A D+ ++ L+ A E S + ++ P P + + + +
Sbjct: 13598 --TVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT 13655
Query: 1137 KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGS--GPWSQTVVGRT 1194
+ S V V + D ++ + + N G+ G S VVG+
Sbjct: 13656 RVS-----------VESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13704
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE 1254
+P+ GP + T+ +M ++W+ P+ D + Y + +++DS
Sbjct: 13705 --GIPT-GPIKFDEV--TAEAMTLKWAP-PKDDGGSEITNY--ILEKRDSVNNKWVTCAS 13756
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTR--IGDGSPSHPPILERTLD--DVPGPPMGILFP 1310
+ ++T L + + Y +V A + +G+G S P + D D P PP +
Sbjct: 13757 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV--- 13813
Query: 1311 EVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTT----ANTATVEVLAPSARQYTATGL 1365
+VR SV L W P G I Y + + + AN + + R + TGL
Sbjct: 13814 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM-----RDFKVTGL 13868
Query: 1366 KPESVYLFRITAQTRKGWGEAA---EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW 1422
Y FR+ A G G+ + E +V D PP +P V ++ SV L W
Sbjct: 13869 TEGLEYEFRVMAINLAGVGKPSLPSEPVVAL----DPIDPPGKPEVI--NITRNSVTLIW 13922
Query: 1423 -EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND 1481
EP DG + Y ++ R+LPS W + + V+ +F V L Y+FR++A N
Sbjct: 13923 TEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13981
Query: 1482 IGDSEFSEESESLTTLQAAPD-EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIR 1540
G S SES T+ + EAPTI+ P +D G I+
Sbjct: 13982 AG--AISAPSESTETIICKDEYEAPTIVL-------------DPTIKD-------GLTIK 14019
Query: 1541 YRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL----SRPSLTQYELDNLNKHRRYE 1596
+ + L ++ G P ++W++ ++ S P+ + + + E
Sbjct: 14020 AGDTIV--LNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14077
Query: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
++ N G + + V V P V + +A + +TW PP L+ I
Sbjct: 14078 YTITATNPFG----TKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP-LEDGGSPI 14132
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
+ Y + E R L V + V K + G Y+ V+A N G G +S P
Sbjct: 14133 KSYILEKRETSR-LLWTVVSEDIQSCRHVATKLIQG-NEYIFRVSAVNHYGKGEPVQSEP 14190
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKI 1773
+ + P P + S +T + VSW+ P G + GY + + V I
Sbjct: 14191 VKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAI 14250
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPPGV 1830
T S L KV L EG TY FR+ A+ GP EA+ + + A PGPP
Sbjct: 14251 KTPV----SDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 14306
Query: 1831 PIIVRYSSAIA-IHWSSGDPGKG-PITRYVIEARPSDEGLWDILIKDIPKEVSSYT-FSM 1887
P + + A + W G IT YV+E + + W IKD T F +
Sbjct: 14307 PHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVV 14363
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPS-SPSQSVPAQKANPFYE 1928
L+ Y+FR+ A+ND G G P+ P + ++ P +E
Sbjct: 14364 PDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFE 14405
Score = 200 bits (508), Expect = 1e-50
Identities = 369/1617 (22%), Positives = 631/1617 (39%), Gaps = 210/1617 (12%)
Query: 477 ATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
A N+ GV + SA + R PP + V +GT ++V + P T+ W
Sbjct: 9721 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLT--W 9778
Query: 532 EKDGATLGTESHP--------RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
K P ++ +D +L I Q+ D G YT ++ G S+
Sbjct: 9779 FKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 9838
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
L V P P P+ +V + L+W P D G S + Y++E E N V ++S
Sbjct: 9839 LNVLGRPGPPVGPIK-FESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSS 9897
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--------PP 694
+PK + T+ L+ Y FR+ A N G G+ L EP TA P
Sbjct: 9898 -EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE--------PLDSEPETARNLFSVPGAP 9948
Query: 695 QNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
S T S+ + W+ P E + GY + ++K + + + L
Sbjct: 9949 DKPTVSSVTRNSMTVNWEEP-EYDGGSPVTGYWLEMKDT---TSKRWKRVNRDPIKAMTL 10004
Query: 755 ------EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST-- 806
LI ++Y+ V A N+AG+G S T + P PPG + T+ T
Sbjct: 10005 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD-PIAPPGPPFPKVTDWTKS 10063
Query: 807 TIRFTWNAP---SPQFINGINQGYKLIA---WEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ W+ P + G YK WE +++EV V+G
Sbjct: 10064 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL-----------VVTG 10112
Query: 861 LKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP- 918
LK+ Y V G G P ++ + + P D L S ++
Sbjct: 10113 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP----------DLQLDASVRDRI 10162
Query: 919 -GEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVT-GLTALTTYTI---------E 967
G++ RI + VT + TL T TA+++ +
Sbjct: 10163 VVHAGGVI---RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQG 10219
Query: 968 VAAMTSKGQGQVSASTISSGVPPELPGPP-TNLGISNIGPRSVTLQ-FRPGYDGKTSISR 1025
V ++ +K + TI V ++PGP T N+ S L F P DG + I+
Sbjct: 10220 VYSLLAKNEAGERKKTIIVDVL-DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITN 10278
Query: 1026 WLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 1085
+++E + + W + +A V L Y FR+ N +G P +
Sbjct: 10279 YVIEKRES---DRRAWTPVTYTVTRQNAT---VQGLIQGKAYFFRIAAENSIGMGPFVET 10332
Query: 1086 SRKIQTLQAPPDMA--PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG 1143
S + ++ P + P ++ ++ ++ ++ L W P +Y+G E + Y ++ SR G
Sbjct: 10333 SEAL-VIREPITVPERPEDLEVKEVTKNTVTLTWNP---PKYDGGSEIINYVLE-SRLIG 10387
Query: 1144 HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRESVPS 1200
K + + R YT++ L+E Y +V A N +G G S + + + + P+
Sbjct: 10388 TEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPT 10447
Query: 1201 ---SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS-DTQPRFWLVEGN 1256
++ + ++ R+S P+ + V+ ++ T P +E
Sbjct: 10448 LHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALE-- 10505
Query: 1257 SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTT 1315
A+ + GKY + + + + S + + D PGPP+G + F EV
Sbjct: 10506 -KIKAKRSDSGKYCVV---------VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555
Query: 1316 SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV-YLFR 1374
+ + W+PP G + I + + V + SA+ E Y+FR
Sbjct: 10556 YMVISWKPPLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKLLEGKDYIFR 10613
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
I A+ G + + + + R R P P +P+V + V S L++W DG P+
Sbjct: 10614 IHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE--VTKDSALVTWNKPHDGGKPIT 10671
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESES 1493
Y ++ RE S RWA + H + F V L Y+FRV A N+IG + S S+
Sbjct: 10672 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10731
Query: 1494 LTTLQAAPDEAPTILSVTPHTT-TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGF 1552
+ +P + TT SV + WQPP D +LG+ + Y+++ E R
Sbjct: 10732 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG-GSKILGYIVEYQKVGDEEWR-- 10788
Query: 1553 TLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSS 1611
R + P S P T+Y++ L + Y+ R+ NA GE P+
Sbjct: 10789 --RANHTPE---------------SCPE-TKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 10830
Query: 1612 PPQEVFVGEAVPTAAPRNVVVHGATATQLDV-TWEPPPLDSQNGDIQGYKIYFWEAQRGN 1670
P+ V V + + P +++ A + + + L + + K+ + + R
Sbjct: 10831 VPEPVLVKDRL---EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA 10887
Query: 1671 LTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSV 1730
T+ + + ++++N + S+ N AG T + P P +
Sbjct: 10888 PTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGS---KTVSVKVLVLDKPGPPRDL 10944
Query: 1731 KFSELTTTSVNVSWEAP------QFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPL 1784
+ SE+ S ++W+ P N ++E + SP+ SK K +
Sbjct: 10945 EVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSK-----KKSHF-- 10997
Query: 1785 WLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAP--GPPGVPIIVRY----S 1837
K L EG Y FR+ A+ + GP +E T P + PPG P + +
Sbjct: 10998 ---AKHLNEGNQYLFRVAAENQYGRGPFVE---TPKPIKALDPLHPPGPPKDLHHVDVDK 11051
Query: 1838 SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSY 1896
+ +++ W+ D G PIT Y++E + +EG D + K V++ + L+ G +Y
Sbjct: 11052 TEVSLVWNKPDRDGGSPITGYLVEYQ--EEGTQDWIKF---KTVTNLECVVTGLQQGKTY 11106
Query: 1897 DFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEEWWFLVVIALVGLIFI--LLLVFVLIIR 1954
FRV A N G G P + ++P + L V + GL+ + F IIR
Sbjct: 11107 RFRVKAENIVGLGLPDT---TIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIR 11163
Query: 1955 GQSKKYAKKTDSGNSAKSGALGHSEMMSLDESSFPALELNNRRLSVKNSFCRKNGLY 2011
G AK T G+ K+ E +++ +F ++ L++KN R G Y
Sbjct: 11164 GVPVPTAKWTTDGSEIKT-----DEHYTVETDNFSSV------LTIKNCLRRDTGEY 11209
Score = 200 bits (508), Expect = 1e-50
Identities = 379/1720 (22%), Positives = 629/1720 (36%), Gaps = 216/1720 (12%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT-LENTLVILSTVAPDAGRYY 182
V H + ++ P P VTW + R +P + I T + +++VI + G Y
Sbjct: 10163 VVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYS 10222
Query: 183 VQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANAR 242
+ A N+ KT I + V +V GP T + T+ + + E +
Sbjct: 10223 LLAKNEAGERKKT---IIVDVLDVPGPVG----TPFLAHNLTNESCKLTWFSPE--DDGG 10273
Query: 243 PLIKLHIIWKKDG---VLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG 299
I ++I K++ + + T+ A ++ A P V
Sbjct: 10274 SPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETS 10333
Query: 300 AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPP------PSITWYKDAAVVEVEK 353
L + EP + PER E+++V PP I + ++ ++ EK
Sbjct: 10334 EALVIREP---ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10390
Query: 354 LTRFRQRN--DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL-- 409
+ N + GL DT ++ A N G+ + S + + L
Sbjct: 10391 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10450
Query: 410 ----DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
T+ G + L SG P+P ++W K E + + TP I
Sbjct: 10451 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 10510
Query: 466 HISDAGTYTCLATNSRG----------------------VDEASADLVVWARTRITKPPQ 503
SD+G Y + NS G DE + D +V + KPP
Sbjct: 10511 R-SDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVIS----WKPPL 10565
Query: 504 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
D S + + + + +W + ++ ++ G +I + + +
Sbjct: 10566 DDG------GSKITNYIIEKKEVGKDVW-MPVTSASAKTTCKVSKLLEGKDYIFRIHAEN 10618
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLI 623
+ + ++S DS A R R +P AP+ P+ T V + + +TW KP DG P+
Sbjct: 10619 LYGISDPLVS----DSMKAKDRFR-VPDAPDQPIVT--EVTKDSALVTWNKPHDGGKPIT 10671
Query: 624 RYILEMSEN-NAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
YILE E + W + T V L+ Y+FR+ A N++G G S ++
Sbjct: 10672 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10731
Query: 683 VSLPEE-PPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQF 741
V + +PP N A T S+ + WQPP + IL GYI+ Y G +
Sbjct: 10732 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKIL-GYIVEYQKVGDEEWRRA 10790
Query: 742 KNITDA-DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV-H 799
+ ++ + L Y+ V A N+AG + V E L PP +
Sbjct: 10791 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES-DPAHVPEPVLVKDRLEPPELILD 10849
Query: 800 AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS 859
A I+ I G+ + + W+ E + T D VG
Sbjct: 10850 ANMAREQHIKVGDTLRLSAIIKGV--PFPKVTWKKEDRDAPTKARI-----DVTPVGSKL 10902
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
++ + T T + D PGP L SEI S ++W+EP
Sbjct: 10903 EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL 10962
Query: 920 EKNG-ILTGYRI--------SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
+ G ++T Y + W + T+ + +H+ + L Y VAA
Sbjct: 10963 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH---------LNEGNQYLFRVAA 11013
Query: 971 MTSKGQGQV--SASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWL 1027
G+G + I + P PGPP +L ++ V+L + +P DG + I+ +L
Sbjct: 11014 ENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYL 11073
Query: 1028 VEAQVGVVGEG-EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS-PPSQP 1085
VE Q EG ++W+ ++N V L Y FR++ NIVG P +
Sbjct: 11074 VEYQ----EEGTQDWIKFKTVTN----LECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI 11125
Query: 1086 SRKIQTLQAPPD-------MAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY 1138
+ Q PP + V T +R +P+P ++ + +
Sbjct: 11126 PIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI------ 11179
Query: 1139 SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESV 1198
++D H V D TI++ Q+ NA GS V T V
Sbjct: 11180 -KTDEH----YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGS---KTVAVHLTVLDV 11231
Query: 1199 PS--SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV--E 1254
P +GP N+ L T M + W + P+ D V+ Y V + DT+ W V
Sbjct: 11232 PGPPTGPINI--LDVTPEHMTISW-QPPKDDGGSPVINYIV----EKQDTRKDTWGVVSS 11284
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVR 1313
G+S ++ L K Y +V A +IG G P P + + P PP + ++
Sbjct: 11285 GSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDIT 11344
Query: 1314 TTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+ + W P + G I Y + R T V + ++ TGL + Y
Sbjct: 11345 ENAATVSWTLPKSDGGSPITGYYMERR--EVTGKWVRVNKTPIADLKFRVTGLYEGNTYE 11402
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLS 1430
FR+ A+ G + + + + P PP P ++ + R + L+ +P SDG S
Sbjct: 11403 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS-RETADLVWTKPLSDGGS 11461
Query: 1431 PVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
P+ Y ++ ++ + +W + +F V L Y+FR+KA N +G+ E E
Sbjct: 11462 PILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11521
Query: 1491 SESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLR 1550
+ES+ A IL P V R + + +G IR
Sbjct: 11522 AESVI--------AKDILH-PPEVELDVTCR-------DVITVRVGQTIRILA------- 11558
Query: 1551 GFTLRGINNPGATWAELTSMY-------SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
++G P TW + + +++L R L E + H +Y I S N
Sbjct: 11559 --RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRAD-HGKYII--SAKN 11613
Query: 1604 AVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF 1663
+ G S V +N+ V T ++WE PLD+ +I + + +
Sbjct: 11614 SSGHAQGS----AIVNVLDRPGPCQNLKVTNVTKENCTISWE-NPLDNGGSEITNFIVEY 11668
Query: 1664 -------WEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP---RS 1712
W ++T+R +K LA N Y V A N G GP
Sbjct: 11669 RKPNQKGWSIVASDVTKRLIKANLLANNE-----------YYFRVCAENKVGVGPTIETK 11717
Query: 1713 TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
TP P P ++ ++ T V + W P + G
Sbjct: 11718 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGG 11757
Score = 198 bits (503), Expect = 5e-50
Identities = 328/1450 (22%), Positives = 557/1450 (38%), Gaps = 178/1450 (12%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSA 582
P+VT W K G +D L I + D G Y+ +++ G +
Sbjct: 12264 PKVT----WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12319
Query: 583 HLRVRQLPHAPEHPVATL--STVERRAINLTWTKPF-DGNSPLIRYILEMSE-NNAPWTV 638
++RV P PV+ L S V + + +++W P DG S + YI+E E + W+
Sbjct: 12320 NVRVLDTPG----PVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWST 12375
Query: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--PPQN 696
+ V K TS V LVP Y FR+ AVN+ G G D + L +P + PP+
Sbjct: 12376 VTPEV--KKTSFHVTNLVPGNEYYFRVTAVNEYGPG-VPTDVPKPVLASDPLSEPDPPRK 12432
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED 756
+ + T S + W PP + GYI Y P + D+ +L++
Sbjct: 12433 LEVTEMTKNSATLAWLPPLRD-GGAKIDGYITSYREEEQPADRWTEYSVVKDL-SLVVTG 12490
Query: 757 LIIWTNYEIEVAAYNSAGL-------GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIR 809
L Y+ VAA N+ G+ GVY +K L + P + +A I
Sbjct: 12491 LKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE---QLLPPKILMPEQITIKAGKKLRIE 12547
Query: 810 -FTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYF 868
+ P P W+ ++E VT + DS + + + + +
Sbjct: 12548 AHVYGKPHP-----------TCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 12596
Query: 869 TSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
S+ + G + +V D PG P S+I + +SW P E G +T
Sbjct: 12597 YSLTAENSSGTDTQKIKVVVM---DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 12653
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTIS 985
Y + + +R + VT RV L Y V A G + +++ +
Sbjct: 12654 NYIVEKCDVSRGDW-VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 12712
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLI 1044
+ P +P P N ++ + + + + RP DG + I +L+E + E L+
Sbjct: 12713 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK-------ERNSLL 12765
Query: 1045 HQLSNEPDARSMEVP--DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQT-LQAPPDMAPA 1101
+N+ RS E P L YSFR+ +N G+SPPS+P+ + + P P
Sbjct: 12766 WVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE 12825
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
+ + ++ + +W R +++G + +GY ++ + G + ++ + +Y
Sbjct: 12826 VIDVTKSTVSLIWAR------PKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 12879
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRW 1220
T LEE +Y+ + A A+ P S+ T + + P + S + V+
Sbjct: 12880 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPVT--ILAENVPPRIDLSVAMKSLLTVKA 12937
Query: 1221 SEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLG-KYVLYEVQVLAF 1279
+ L V K + + W +G + A+ + + L +++ +
Sbjct: 12938 G-------TNVCLDATVFGKPMPTVS----WKKDGTLLKPAEGIKMAMQRNLCTLELFSV 12986
Query: 1280 TRIGDG---------SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
R G S S ++ + D PGPP + ++ + L W+PP G
Sbjct: 12987 NRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS 13046
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA-EA 1389
+ I + T+ N A V P + L Y FRI A+ + G G+
Sbjct: 13047 EITNYIVDKRETSRPNWAQVSATVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTE 13105
Query: 1390 LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWA 1448
+ D P P++ ++ + +SW+ P DG SP+ Y ++ RE + W
Sbjct: 13106 PAIAKNPYDPPGRCDPPVI--SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWT 13163
Query: 1449 LHSASVSHNASSFIVDR------LKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-P 1501
+ I++R L+ T Y+FRV A N G + S+ S++ P
Sbjct: 13164 KVNRKP-------IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYP 13216
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
P V T +SV + W PA D + I+ G+ +
Sbjct: 13217 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPII----------------GYLVEVKRADS 13260
Query: 1562 ATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG-EGPSSPPQE----- 1615
W +++ T++E+ L + +Y+ R+ N +G PS P +
Sbjct: 13261 DNWVRCNLPQNLQK------TRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 13314
Query: 1616 -VFVGEAVPTAAPRNVVVHGATATQ---LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL 1671
+ E A R ++ A T + V PPP KI W NL
Sbjct: 13315 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPP-----------KI-TWSKPNVNL 13362
Query: 1672 TERV-----KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSA 1726
+R+ T F + ++ +N+ Y A + N+ G + T P
Sbjct: 13363 RDRIGLDIKSTDF--DTFLRCENVNKYDAGKYILTLENSCG---KKEYTIVVKVLDTPGP 13417
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P +V E++ S V+WE P G +V + + S + T K +
Sbjct: 13418 PVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTS----F 13473
Query: 1787 KVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAPGPPGVPIIVR--YSSAIAIH 1843
+V +L EG +Y FR+ A+ + G E + PGP V + VR S+ +I
Sbjct: 13474 RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQ-TPGPV-VDLKVRSVSKSSCSIG 13531
Query: 1844 WSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
W G I YV++ ++E W ++K + S +S L G Y FRV A
Sbjct: 13532 WKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-----SLQYSAKDLTEGKEYTFRVSA 13585
Query: 1903 VNDYGFGTPS 1912
N+ G GTPS
Sbjct: 13586 ENENGEGTPS 13595
Score = 195 bits (495), Expect = 5e-49
Identities = 428/1972 (21%), Positives = 746/1972 (37%), Gaps = 272/1972 (13%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP 135
++++ L F+R N+ G R+ + V E E +RA
Sbjct: 20060 HVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAG 20119
Query: 136 R-------IASFPQPQVTWFRDGRKIPPSSRI--AITLEN-TLVILSTVAPDAGRYYVQA 185
I+ P P+VT RDG + + R IT EN T+ + +V DAGRY + A
Sbjct: 20120 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 20179
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVA--------GTSEVTLEC 237
N T I + V + GP P P +I SV G S+VT
Sbjct: 20180 ANSSG---TTKAFINIVVLDRPGP--PTGPVVISDITEESVTLKWEPPKYDGGSQVTNYI 20234
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI---------SDHNRRLTIPNPTG-SDAGYYECEAV 287
+ +W + ++ + ++ R+ N G SD C V
Sbjct: 20235 LLKRETSTA---VWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTV 20291
Query: 288 LRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAA 347
+ P +++ + ++ VV + K SI W K
Sbjct: 20292 KLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD--RNSILWQKANK 20349
Query: 348 VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS--------------- 392
+V + T F+ +GL+ + F+ +A NAAG + S
Sbjct: 20350 LVI--RTTHFKVTTIS----AGLIYE----FRVYAENAAGVGKPSHPSEPVLAIDACEPP 20399
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRF 452
+ +T I+ N DG S + P W K F
Sbjct: 20400 RNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS------------F 20447
Query: 453 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV-------VWARTRITKPPQDQ 505
T + +IS + + A N+ G +++V + I P +
Sbjct: 20448 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYT 20507
Query: 506 SVIK---GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWS 561
V+K GT + G++ P TI W KD L T + + + S+ I
Sbjct: 20508 EVVKYRAGTSVKLRAGISGKPAPTIE--WYKDDKELQTNALVCVENTTDLASILIKDADR 20565
Query: 562 GDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNS 620
+ G Y ++ +A G+ S + +++ P P P+ TV I L W P D G +
Sbjct: 20566 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIE-FKTVTAEKITLLWRPPADDGGA 20624
Query: 621 PLIRYILEMSENN-APWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKD 679
+ YI+E E + W+++ ++ +T ++ Y FR+ AVN G G+ +
Sbjct: 20625 KITHYIVEKRETSRVVWSMVSEHLEE--CIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20682
Query: 680 TERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII----RYCLAGL 735
V+ PP + T S+ + W P + I GY + + L
Sbjct: 20683 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI-SGYFLEKRDKKSLGWF 20741
Query: 736 PVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPP 795
V + T V L ++Y+ V A N+AG G +S +E+ P PP
Sbjct: 20742 KVLKETIRDTRQKVTGLTEN-----SDYQYRVCAVNAAGQGPFSEP-SEFYKAADPIDPP 20795
Query: 796 G---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDS 852
G + + ++I W+ P + + GY ++ +EEE T V+ + + +
Sbjct: 20796 GPPAKIRIADSTKSSITLGWSKPVYDGGSAVT-GY-VVEIRQGEEEEWTTVSTKGEVRTT 20853
Query: 853 IHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEI-LDTS 910
+V VS LK Y+ V G G P + V+ + + P EI LD +
Sbjct: 20854 EYV--VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP-------EIDLDVA 20904
Query: 911 LKVSW-QEPGEKNGILTGYR------ISWEEYNRTNTRVTHY-LPNVTLEYRVTGLTALT 962
L+ S + GE +L ++ ++W + + Y + N +T
Sbjct: 20905 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 20964
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKT 1021
T + G G+ +ST+S V + P L + ++ +VTL + P DG +
Sbjct: 20965 NDTGKYILTIENGVGEPKSSTVSVKVL-DTPAACQKLQVKHVSRGTVTLLWDPPLIDGGS 21023
Query: 1022 SISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +++E + W ++ S++ + S ++ DL+ T + FR+ N +G
Sbjct: 21024 PIINYVIEKRDATK---RTWSVV---SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 21077
Query: 1082 PSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS 1141
P + + ++ + P + ++S++ +++TS+ L W + +++G Y ++ R
Sbjct: 21078 PCETTEPVKAAEVPAPIR--DLSMKDSTKTSVILSWT---KPDFDGGSVITEYVVE--RK 21130
Query: 1142 DGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPS 1200
+T SH + + + L+E + +V A N G S P +
Sbjct: 21131 GKGEQTWSHAGISKT-CEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------VT 21176
Query: 1201 SGPTNVSALATTSSSMLVRWSEVPEAD---RNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
GP V L T V S++P A R G + ++ YK K + WL +G
Sbjct: 21177 IGPITVKELIITPE---VDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSIS--WLKDGLP 21231
Query: 1258 SRSAQLTGLGKY---VLYEVQVLA------FTRIGDGSPSH--PPILERTLDDVPGPPMG 1306
+ ++ K + ++ +T I D + PI TL P
Sbjct: 21232 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 21291
Query: 1307 ILFPEVRTTSVRLIWQPPAAPNG-IILAYQITHRLNTTTANTATVEVLAPSARQ-YTATG 1364
I F E++ SV L W P G I Y I R T+ T V + AR +
Sbjct: 21292 IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR---ETSQTNWKMVCSSVARTTFKVPN 21348
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWE 1423
L ++ Y FR+ A+ R G + + ++ + + R P PP +P++ +V + + L+W+
Sbjct: 21349 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY--NVTSDGMSLTWD 21406
Query: 1424 -PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
P DG S V + ++ +E S W + S + + L Y+FRV A N
Sbjct: 21407 APVYDGGSEVTGFHVEKKERNSILWQKVNTSPI-SGREYRATGLVEGLDYQFRVYAENSA 21465
Query: 1483 GDSEFSEESE-SLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRY 1541
G S S+ S+ +L P P + VT T T ++W PP D + I+ G+ I
Sbjct: 21466 GLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETIT---LKWNPPLRDGGSKIV-GYSIEK 21521
Query: 1542 RELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSV 1601
R+ W N + S QY + L+ RYE R+
Sbjct: 21522 RQ----------------GNERWVRC-------NFTDVSECQYTVTGLSPGDRYEFRIIA 21558
Query: 1602 YNAVGEGPSSPPQE-----VFVGEAVPTAAP------RNVVVHGATATQLDVTWEPPPLD 1650
NAVG SPP + + E VP +++ + ++ + P+
Sbjct: 21559 RNAVGT--ISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVP 21616
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
G +I +R N+ T L S+ +++ T + +V A NA+G
Sbjct: 21617 RVTWFKDGVEI----EKRMNMEI---TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21669
Query: 1711 RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV 1770
+ Q P ++F+ +T + + W+AP + + C+P+
Sbjct: 21670 AEIKVKVQDTPGKVVGP--IRFTNITGEKMTLWWDAP------------LNDGCAPITHY 21715
Query: 1771 SKIVTVDVKGNSPL-WLKVKDLAE-----------GVTYRFRIRA-KTFTYGPEIEANVT 1817
++ + S L W ++D E G Y+FR+ A F G ++++
Sbjct: 21716 ----IIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPV 21771
Query: 1818 TGPGE-GAPGPPGVPIIVRYS-SAIAIHWSSGDP-GKGPITRYVIEARPSDEGLWDILIK 1874
+ P PG+P + ++I + W+ + G I +Y++E R W +I
Sbjct: 21772 VAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVIS 21831
Query: 1875 DIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQK-ANP 1925
P +S F + L G Y+F V+A N G G S S+ + ++ NP
Sbjct: 21832 KRP--ISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNP 21881
Score = 193 bits (490), Expect = 2e-48
Identities = 350/1604 (21%), Positives = 572/1604 (35%), Gaps = 169/1604 (10%)
Query: 378 FQCFARNAAGEVQTSTYLAVTS---IAPNIT-RGPLDSTVI--DGMSVVLACETSGAPRP 431
F+ A N GE S V +AP++ +G D + + + L G P P
Sbjct: 13581 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13640
Query: 432 AITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV 491
+++W+KGE LA+ ++ + + +L++ SDAG YT N G E + +
Sbjct: 13641 SVSWKKGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 13699
Query: 492 VWARTRITKPPQDQSVIKGTQASMVCGVTHDP--RVTIRYIWEK----DGATLGTESHPR 545
V + I P + ++ D YI EK + + S +
Sbjct: 13700 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 13759
Query: 546 IRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
R LH ++ + + G +P AP P + V
Sbjct: 13760 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP--PPPNIVDVRH 13817
Query: 606 RAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFR 664
+++LTWT P G SP+ Y LE E N+ + V GL Y+FR
Sbjct: 13818 DSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFR 13877
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEP-----PTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
+ A+N G G + SLP EP P PP T S+ + W P +
Sbjct: 13878 VMAINLAGVG-------KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP--KYD 13928
Query: 720 NG-ILKGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
G L GYI+ LP K N + + DL+ YE + A N+AG
Sbjct: 13929 GGHKLTGYIVE--KRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13986
Query: 778 YSSKVTEW----------TLQGVPTVPPG-NVHAEATNSTTIRFTWNAPSPQFINGINQG 826
S+ TE T+ PT+ G + A T P P+ + ++
Sbjct: 13987 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPK--SSWSKA 14044
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQ 886
K I + ++T +T+ P + +K T T
Sbjct: 14045 GKDI-----RPSDITQITSTP-------TSSMLTIKYATRKDAGEYTITATNPFGTKVEH 14092
Query: 887 LVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
+ T DVPGP G + S + ++W P E G + Y + E +R V
Sbjct: 14093 VKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE 14152
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNI 1004
+ + T L Y V+A+ G+G+ V + + PGPP +SN+
Sbjct: 14153 -DIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNV 14211
Query: 1005 GPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNP 1063
+ T+ + RP DG + I+ + VE + E + + + +V L
Sbjct: 14212 TKNTATVSWKRPVDDGGSEITGYHVERR-----EKKSLRWVRAIKTPVSDLRCKVTGLQE 14266
Query: 1064 FTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPE 1122
+ Y FR+ N G PPS+ S + A P P+N + ++ S L W +
Sbjct: 14267 GSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAW---GK 14323
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G E GY +++ + + + DL+ +Y ++ A N G
Sbjct: 14324 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14383
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
G + V E V + A +++VR L ++ K
Sbjct: 14384 VG---EPAVIPDVEIVEREMAPDFELDAELRRTLVVRAG-----------LSIRIFVPIK 14429
Query: 1243 DSDTQPRFWLVEG-NSSRSAQLTGLGKYVL--------YEVQVLAFTRIGDGSPSHPPIL 1293
W + N A + + L Y+ T +
Sbjct: 14430 GRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14489
Query: 1294 ERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVL 1353
R L D PGP + + ++ SV L W P G + I + T + +T
Sbjct: 14490 VRVL-DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTK 14548
Query: 1354 APSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRP-MVQQED 1412
Y TGL Y FR+ A+ G GE E TTE + PS P + D
Sbjct: 14549 CHKC-TYKVTGLSEGCEYFFRVMAENEYGIGEPTE----TTEPVKASEAPSPPDSLNIMD 14603
Query: 1413 VRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTS 1471
+ +V L+W +P DG S + Y I+ + S +W H +V +V L
Sbjct: 14604 ITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWT-HITTV--KGLECVVRNLTEGEE 14660
Query: 1472 YKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKIN 1531
Y F+V A N G S P + V+++ Q +
Sbjct: 14661 YTFQVMAVNSAGRS-------------------------APRESRPVIVKEQTMLPE--- 14692
Query: 1532 GILLGFRIRYRELLY----EGLR-GFTLRGINNPGATWAELTSMYSM-RNLSRPSLTQYE 1585
L R Y++L+ + ++ + G P TW + + + ++ +
Sbjct: 14693 ---LDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 14749
Query: 1586 LDNLNKHRRYE---IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDV 1642
+ N+N+ R + ++ N VGE +V PT + ++ +
Sbjct: 14750 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGP---IKFDEVSSDFVTF 14806
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
+W+PP D I Y + + E T+ + K LT Y V A
Sbjct: 14807 SWDPPENDG-GVPISNYVVEMRQTDSTTWVELATTVI--RTTYKATRLTTGLEYQFRVKA 14863
Query: 1703 FNAAGDGPRSTPT--QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRL 1759
N G GP T P P + + + +T S+ +SW P G + GY +
Sbjct: 14864 QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHV 14923
Query: 1760 VYEPCSPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVT 1817
+ + + VSK + V GN K L +G+ Y FR+ A+ +
Sbjct: 14924 ERKERNGILWQTVSKAL---VPGNI---FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSE 14977
Query: 1818 TGPGEGAPGPPGVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKD 1875
PPG P+ + + + + W+ + G IT Y++E R G W +K
Sbjct: 14978 PMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW---LKA 15034
Query: 1876 IPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG-FGTPSSPSQSV 1918
+ F++ L +Y+FRVIA N G PS PS ++
Sbjct: 15035 NFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAI 15078
Score = 193 bits (490), Expect = 2e-48
Identities = 343/1510 (22%), Positives = 596/1510 (39%), Gaps = 171/1510 (11%)
Query: 473 YTCLATNSRG-VDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVT 526
+ +A N +G D S + + A+ + +P SV G + ++ P+ T
Sbjct: 16829 FRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT 16888
Query: 527 IRYIWEKDGATLGTESHPRIR--LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
I W KDG L + + LD +L I +T D G Y V + G + S +
Sbjct: 16889 IT--WTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQYGITVANVVGQKTASIEI 16945
Query: 585 RVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLLAS 642
P P+ PV V +I L+W P + G + YI++ + W V+ A+
Sbjct: 16946 VTLDKPDPPKGPVK-FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 17004
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERV--SLPEEPPTAPPQNVIAS 700
V T++ V L YQFR+ A N G+ F+ +++ + P + P PP A+
Sbjct: 17005 V--ARTTLKVTKLKTGTEYQFRIFAENRYGQS-FALESDPIVAQYPYKEP-GPPGTPFAT 17060
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED---- 756
+ S++IQW P + + ++ ++ R + +I VN ++ D
Sbjct: 17061 AISKDSMVIQWHEPVNNGGSPVIGYHLERK---------ERNSILWTKVNKTIIHDTQFK 17111
Query: 757 ---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWN 813
L YE V A N G+G +SK +E + P PPG I W
Sbjct: 17112 AQNLEEGIEYEFRVYAENIVGVGK-ASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 17170
Query: 814 APSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVL 872
P + G + + E+ + + +F + I F VSGL + Y V+
Sbjct: 17171 KPV------YDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVI 17224
Query: 873 CFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRI 930
G P + + ++V P +S ++ V+ E + G +
Sbjct: 17225 AKNAAGAISKPSDSTGPITAKDEVELP--RISMDPKFRDTIVVNAGETFRLEADVHGKPL 17282
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI--SSGV 988
E+ R + + + E + T AL ++ A GQ + AS + S
Sbjct: 17283 PTIEWLRGDKEIEE---SARCEIKNTDFKALLI--VKDAIRIDGGQYILRASNVAGSKSF 17337
Query: 989 PPEL-----PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEW 1041
P + PGPP + ++ + +L + P DG + IS ++VE + W
Sbjct: 17338 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRET---SRLAW 17394
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPA 1101
++ ++E S++V L Y FR+ VN G P + + + P
Sbjct: 17395 TVV---ASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPK 17451
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
++ + ++ S+ + W + +G E +GY ++ + D G + R+ +
Sbjct: 17452 SLEVTNIAKDSMTVCWN---RPDSDGGSEIIGYIVE--KRDRSGIRWIKCNKRRITDLRL 17506
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLV 1218
+ L E EY +V A NA G G P TV + + V GP TN + TT +S+ +
Sbjct: 17507 RVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITL 17566
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
W + P D +LGY V + D + G +++ L ++ Y+++V A
Sbjct: 17567 AWGK-PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17625
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH 1338
++G G + P + D + P + L E+R GI++ +
Sbjct: 17626 LNKVGLGEATSVPGTVKPEDKLEAPELD-LDSELR--------------KGIVVRAGGSA 17670
Query: 1339 RLNTTTANTATVEVL-APSARQYTATGLKPESVYLFRITAQT--RKGWGE---------A 1386
R++ T E+ + ++T + V +++ R G+
Sbjct: 17671 RIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG 17730
Query: 1387 AEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSG 1445
+++ VT + D P PP V++ VR S L WEP DG + V+ Y I RE S
Sbjct: 17731 SKSAFVTVKVLDTPGPPQNLAVKE--VRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--ST 17786
Query: 1446 RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAP 1505
R A + S + +SF V+ L Y FRV A N+ G E +++ A P P
Sbjct: 17787 RKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKA--AEPPSPP 17844
Query: 1506 TILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWA 1565
+++T + TS + W+ P D + +L G+ + E+ +G +++
Sbjct: 17845 GKVTLTDVSQTSASLMWEKPEHDGGSRVL-GYVV---EMQPKGTEKWSI----------- 17889
Query: 1566 ELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVP-- 1623
++ + + L+ + Y+ R+ YN G+ S P+ + V
Sbjct: 17890 ----------VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK---SDPRVLGVPVIAKDL 17936
Query: 1624 TAAPRNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA 1681
T P + + Q D+ E P + +I K + + T RV A
Sbjct: 17937 TIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVK----DGEPLKQTTRVNVEETA 17992
Query: 1682 ENSV---KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
++V K N + Y +V A N+AG + + P P V+F E++
Sbjct: 17993 TSTVLHIKEGNKDDFGKY--TVTATNSAGTATENLSVIVLEKPGPPVGP--VRFDEVSAD 18048
Query: 1739 SVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTY 1797
V +SWE P + G + Y + E +V+ V + +K+ L G Y
Sbjct: 18049 FVVISWEPPAYTGGCQISNY--IVEKRDTTTTTWHMVSATVARTT---IKITKLKTGTEY 18103
Query: 1798 RFRIRAKTFTYGP----EIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGK 1851
+FRI A+ YG + +A + P + PGPPG P + S + + W + G
Sbjct: 18104 QFRIFAEN-RYGKSAPLDSKAVIVQYPFK-EPGPPGTPFVTSISKDQMLVQWHEPVNDGG 18161
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
I Y +E + + LW L K ++ T +D G+ Y+F+V A N G G P
Sbjct: 18162 TKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD---EGLEYEFKVSAENIVGIGKP 18218
Query: 1912 SSPSQSVPAQ 1921
S S+ A+
Sbjct: 18219 SKVSECFVAR 18228
Score = 192 bits (489), Expect = 2e-48
Identities = 323/1397 (23%), Positives = 511/1397 (36%), Gaps = 198/1397 (14%)
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
R + L I + D GTYT + G+ R+ H+ V P P + T ++
Sbjct: 9083 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVT--DIKAE 9140
Query: 607 AINLTWTKPFD-GNSPLIRYILEM---SENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662
+ LTW P D G S + Y+++ S A W + + K + L+P Y+
Sbjct: 9141 SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK--LIPNGQYE 9198
Query: 663 FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722
FR+ AVN G K + V PP RT S+++ W PP ++ + I
Sbjct: 9199 FRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPI 9258
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED-------LIIWTNYEIEVAAYNSAGL 775
GY + G P + ++ A + + L+ L+ Y+ A N+AG+
Sbjct: 9259 -TGYWLEKREEGSP---YWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGI 9314
Query: 776 GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT---IRFTWNAPSPQFINGINQGYKLIAW 832
G S+ ++ + G P PPG T I W P+ + G + +
Sbjct: 9315 GP-PSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAK------DGGSPIKGY 9367
Query: 833 EPEQEEEVTMVTARPNFQDSIHVG---FVSGLKKFTEYFTSVLCFTTPGDGPRS--TPQL 887
E +EE T R N D + V LK+ +Y V G+ S T ++
Sbjct: 9368 IVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI 9427
Query: 888 VRTH-EDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYL 946
T ++ P + + L + P G T + SWE + + +
Sbjct: 9428 PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTP-KSSWEFDGKAKKAMKDGV 9486
Query: 947 PNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA------STISSGVP-PELPGPPTNL 999
++ + ++ + I + G+ ++A T + V ++PGPP +L
Sbjct: 9487 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9546
Query: 1000 GISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS--M 1056
+S+I S L ++ P DG I +++E + +G+ W ++ PD S
Sbjct: 9547 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVN-----PDCGSTTF 9598
Query: 1057 EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQA--PPDMAPANVSLRTASETSLW 1114
VPDL Y FR+R N G PP + ++ PPD P + + ++ ++
Sbjct: 9599 VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPD-PPIKLKIGLITKNTVH 9657
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ----DRVERDYTIEDLEEWTE 1170
L W P + +G Y ++ D G Q D E +T+EDL E E
Sbjct: 9658 LSWKP---PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGE 9714
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
Y +V+A NA G S TV GP + S L + EV E
Sbjct: 9715 YEFRVKAVNAAGVSKPSATV-----------GPCDCQRPDMPPSIDLKEFMEVEEGTNVN 9763
Query: 1231 LV-----------LGYKVMYKEKDS------DTQPRFWLVEGNSSRSAQLTGLGKYVLYE 1273
+V +K K+ D+ DT +V+ + + LY
Sbjct: 9764 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLY- 9822
Query: 1274 VQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIIL 1332
+ A +G S + + PGPP+G I F V + L W PP G +
Sbjct: 9823 -TITAVNNLGTASKE----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKI 9877
Query: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
+ + V P YT L Y+FRI AQ + G GE ++
Sbjct: 9878 TNYVIEKREANRKTWVHVS-SEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPE 9936
Query: 1393 TTEKR-DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALH 1450
T P P +P V V S+ ++W EP DG SPV Y ++ ++ S RW
Sbjct: 9937 TARNLFSVPGAPDKPTV--SSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRV 9994
Query: 1451 SASVSHNAS---SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
+ + S+ V L + Y+FRV A N G S S+ T P
Sbjct: 9995 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPF 10054
Query: 1508 LSVTPHTTTSVLIRWQPPAED---KINGILLGFR--------------IRYRELLYEGL- 1549
VT T +S + W PP +D K+ G ++ ++ +R +L+ GL
Sbjct: 10055 PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLK 10114
Query: 1550 ---------RGFTLRGINNPGATWAELTSMYSMRN-LSRP--SLTQYELDNLNKHRRYEI 1597
R + GI PG E+T + M++ L P L D + H I
Sbjct: 10115 EGAFYKFRVRAVNIAGIGEPG----EVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVI 10170
Query: 1598 RMSVYNAVGEGPS--------SPPQEVFV------------------------------G 1619
R+ Y + P+ + PQE + G
Sbjct: 10171 RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10230
Query: 1620 EA----------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG 1669
E VP + H T +TW P D I Y I E+ R
Sbjct: 10231 ERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPE-DDGGSPITNYVIEKRESDRR 10289
Query: 1670 NLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQG---QTQQAAPSA 1726
T T + + ++ L AY +AA N+ G GP ++ + P
Sbjct: 10290 AWTP--VTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 10347
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P ++ E+T +V ++W P++ G E V E S + G K V
Sbjct: 10348 PEDLEVKEVTKNTVTLTWNPPKYDGG-SEIINYVLE--SRLIGTEKFHKVTNDNLLSRKY 10404
Query: 1787 KVKDLAEGVTYRFRIRA 1803
VK L EG TY +R+ A
Sbjct: 10405 TVKGLKEGDTYEYRVSA 10421
Score = 190 bits (483), Expect = 1e-47
Identities = 365/1536 (23%), Positives = 598/1536 (38%), Gaps = 180/1536 (11%)
Query: 448 QLPRFTPLESGSLLISPTHISDAGT-------YTCLATNSRGV--DEASADLVVWARTRI 498
+LP +++ I TH G + +A N+ GV + + + + AR +
Sbjct: 16107 ELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEV 16166
Query: 499 TKPP-------QDQSVIKGTQASMV-CGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LD 549
P +D V+ ++ V + P TI+ W K L + I+ D
Sbjct: 16167 DPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQ--WIKGDQELSNTARLEIKSTD 16224
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAIN 609
SL + D G Y + + G S + +++V P PE PV +S V
Sbjct: 16225 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVV-ISGVTAEKCT 16283
Query: 610 LTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCA 667
L W P DG S +I YI+E E + WTV+ A+V + VT L+ Y FR+ A
Sbjct: 16284 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTK--LLEGNEYTFRIMA 16341
Query: 668 VNDVGKGQFSKDTERVSL-PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGY 726
VN G G+ + V+ P P AP + + T S+++ W+ P + IL GY
Sbjct: 16342 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV-TKDSMIVVWERPASDGGSEIL-GY 16399
Query: 727 IIRYCLAGLPVGYQFKNITDADVNNLLLE--DLIIWTNYEIEVAAYNSAGLGVYS--SKV 782
++ G ++ + L L LI +YE V+A N+AGL S S
Sbjct: 16400 VLE---KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAY 16456
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN-QGYKLIAWEPEQEEEVT 841
+ PP N +++ +W+ P + G QGY ++ E T
Sbjct: 16457 QKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI--YDGGCEIQGY-IVEKCDVSVGEWT 16513
Query: 842 MVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPV--- 898
M T P + ++ L+K EY + G G H DVPGP+
Sbjct: 16514 MCTP-PTGINKTNIEVEKLLEKH-EYNFRICAINKAGVGE---------HADVPGPIIVE 16562
Query: 899 GHLSFSEI-LDTSLK--VSWQEPGEKNGI--LTGYRISWEEYNRTNTRVTHY-LPNVTLE 952
L +I LD L+ ++ + G + G ++ + + + + +VT
Sbjct: 16563 EKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 16622
Query: 953 YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQ 1012
+ L + Y +T + ++ ++ V + P PP NL ++ I SV++
Sbjct: 16623 FTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL-DTPSPPVNLKVTEITKDSVSIT 16681
Query: 1013 FRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRM 1071
+ P DG + I ++VE + E ++N S ++ L Y FR+
Sbjct: 16682 WEPPLLDGGSKIKNYIVEKR-----EATRKSYAAVVTN-CHKNSWKIDQLQEGCSYYFRV 16735
Query: 1072 RQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPES 1131
N G P+Q + I+ + P P +++ + S+ L W + E++G +
Sbjct: 16736 TAENEYGIGLPAQTADPIKVAEVP--QPPGKITVDDVTRNSVSLSWT---KPEHDGGSKI 16790
Query: 1132 VGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTV 1190
+ Y ++ H + S + + I +L + EY +V A N G S P S V
Sbjct: 16791 IQYIVEMQAK--HSEKWSECARVK-SLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAV 16847
Query: 1191 VGRTRESV--PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQP 1248
++ V P P S + + EVP + R + + D P
Sbjct: 16848 PIVAKDLVIEPDVKPAFSSYSVQVGQDLKI---EVPISGRPKPTITWT-------KDGLP 16897
Query: 1249 RFWLVEGNSSRSAQLTGL----------GKYVLYEVQVLAFTRIGDGSPSHPPILERTLD 1298
N + S LT L G+Y + V +G + S +E
Sbjct: 16898 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV-----VGQKTAS----IEIVTL 16948
Query: 1299 DVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA 1357
D P PP G + F +V S+ L W PP G + I + +TTT T V A A
Sbjct: 16949 DKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTT--TVWDVVSATVA 17006
Query: 1358 R-QYTATGLKPESVYLFRITAQTRKGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
R T LK + Y FRI A+ R G A E+ +V P PP P +
Sbjct: 17007 RTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATA--ISK 17064
Query: 1416 RSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S+++ W EP ++G SPV Y ++ +E S W + ++ H+ + F L+ Y+F
Sbjct: 17065 DSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHD-TQFKAQNLEEGIEYEF 17123
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV A N +G + S+ SE P P + V + T ++W P D +
Sbjct: 17124 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEIT---LQWTKPVYDG-GSM 17179
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
+ G+ + R+L P W + S N+ TQ+ + L + +
Sbjct: 17180 ITGYIVEKRDL---------------PDGRWMKA----SFTNVIE---TQFTVSGLTEDQ 17217
Query: 1594 RYEIRMSVYNAVG--------EGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT---QLDV 1642
RYE R+ NA G GP + EV + R+ +V A T + DV
Sbjct: 17218 RYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADV 17277
Query: 1643 TWEP-PPLDSQNGDIQGYKIYFWEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSV 1700
+P P ++ GD + E+ R + K L + ++++++ +
Sbjct: 17278 HGKPLPTIEWLRGDKE-----IEESARCEIKNTDFKALLIVKDAIRI------DGGQYIL 17326
Query: 1701 AAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLV 1760
A N AG +S P + V+ + +T+ +++W +P +G + V
Sbjct: 17327 RASNVAGS--KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPLQDGGSDISHYV 17383
Query: 1761 YEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIE-ANVTT 1818
E +V +V NS LKV L EG Y FRI A + G +E A V
Sbjct: 17384 VEKRETSRLAWTVVASEVVTNS---LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLM 17440
Query: 1819 GPGEGAPGPP-GVPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDI 1876
PGPP + + ++ + W+ D G I Y++E R W IK
Sbjct: 17441 KNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW---IKCN 17497
Query: 1877 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ ++ + L Y+FRV A N G G PS
Sbjct: 17498 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17533
Score = 190 bits (482), Expect = 1e-47
Identities = 360/1569 (22%), Positives = 576/1569 (36%), Gaps = 242/1569 (15%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G + L +G P P ITW K + IL P +S ++ I + SD G
Sbjct: 7329 TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS-TVTIVDSKRSDTG 7387
Query: 472 TYTCLATNSRGVDEASADLVVWAR---------TRITK--------PPQDQSVIKGTQAS 514
TY A N G A ++ V + T +T PP+D S
Sbjct: 7388 TYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDG------GS 7441
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA 574
+ + R T +W K +T+ + +L N Y RV +
Sbjct: 7442 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKE-------------YIFRVAAE 7488
Query: 575 ---GGNDSRSAHLRVRQLPHAPEHPVATL--STVERRAINLTWTKPFD-GNSPLIRYILE 628
G + A + P P L S + + A+ LTW +P D G SP+ Y +E
Sbjct: 7489 NMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE 7548
Query: 629 MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--P 686
+ + V + K T+ VKGL + Y+FR+ A N G G+ SK TE + + P
Sbjct: 7549 RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP 7608
Query: 687 EEPPTAPPQNVIAS-GRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
+PP P + + G+T S+ + W P H G ++ Y+I G +
Sbjct: 7609 IDPPWPPGKPTVKDVGKT--SVRLNWTKP--EHDGGAKIESYVIEMLKTGTDEWVRVAE- 7663
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEA 802
LL L+ Y V A N AG S S + P PP +
Sbjct: 7664 -GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7722
Query: 803 TNSTTIRFTWNAPSPQFINGI------NQGYKLIAWEP-EQEEEVTMVTARPNFQDSIHV 855
T W P + I + + W+ + + T T P + S++V
Sbjct: 7723 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYV 7782
Query: 856 GFVS-----GLKKFTEYFTSVLC---FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
V+ G +TE SVL FTT PGP L+ ++
Sbjct: 7783 FRVAAENAIGQSDYTEIEDSVLAKDTFTT------------------PGPPYALAVVDVT 7824
Query: 908 DTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTI 966
+ + W+ P G + Y I +E T +RVT + T
Sbjct: 7825 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 7884
Query: 967 EVAAMTSKGQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSI 1023
+V A G G S T +S P P PP +L +++ G + + + ++ P +G + I
Sbjct: 7885 QVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 7944
Query: 1024 SRWLVE-AQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
+ VE VG E+W+ ++ + D + + P Y R+R VN +G S P
Sbjct: 7945 IGYHVEMCPVGT----EKWMRVNSRPIK-DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7999
Query: 1083 SQPSRKIQTLQAPPDMAPANVSLRTAS---------ETSLWLRWMPLPEMEYNGNPESVG 1133
S+ S + + PD P + L T + R +P+P + ++ + + V
Sbjct: 8000 SEISENV--VAKDPDCKP-TIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK 8056
Query: 1134 YKIKYSRSDGHGKTLSHV-VQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVG 1192
+ + + H +H+ V V D I Y + ++ N +GS S V
Sbjct: 8057 ASDRLTMKNDH--ISAHLEVPKSVRADAGI--------YTITLE--NKLGSATASINV-- 8102
Query: 1193 RTRESVPSSGP-TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW 1251
+ + GP ++ A T SS + W E PE D +L Y + + +++ +
Sbjct: 8103 ---KVIGLPGPCKDIKASDITKSSCKLTW-EPPEFDGGTPILHY--VLERREAGRRTYIP 8156
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILF 1309
++ G + S + L Y +V A ++G G P++ + P PP+ +
Sbjct: 8157 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8216
Query: 1310 PEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPE 1368
++ + W+PP G I+ Y I E L P YTA GL+
Sbjct: 8217 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEG 8275
Query: 1369 SVYLFRITAQTRKGWGEAAEALVVT--TEKRDRPQPPSRPM--VQQEDVRARSVLLS--- 1421
Y FR+ A+ G E + A T + D P+ R V++ D A +S
Sbjct: 8276 KEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSP 8335
Query: 1422 -----WEPGSDGLSPV------------RYYTIQTRE---LPSGRWALHSASVSHNASSF 1461
W + + P R +Q E LP + S +
Sbjct: 8336 YPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLR 8395
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH-TTTSVLI 1520
+ D L+P + +K ND G +++ T+ P I V TSVL
Sbjct: 8396 VRDSLRPDHGL-YMIKVENDHG------IAKAPCTVSVLDTPGPPINFVFEDIRKTSVLC 8448
Query: 1521 RWQPPAEDKINGILLGFRIRYRELLYEGLRGFTL--RGINNPGATWAELTSMYSMRNLSR 1578
+W+PP +D + I+ +TL + P + W +TS ++R+
Sbjct: 8449 KWEPPLDDGGSEII----------------NYTLEKKDKTKPDSEWIVVTS--TLRH--- 8487
Query: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV-PTAAPRNVVVHGATA 1637
+Y + L + + Y R+ N G GP + + + P AP +V T+
Sbjct: 8488 ---CKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS 8544
Query: 1638 TQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQRGNLT--ERVKTLFLAENSVKLKNLTGYT 1694
+ V W P NG I G Y+ E + N T RV L + L
Sbjct: 8545 NSMLVKWNEP---KDNGSPILG---YWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 8598
Query: 1695 AYMVSVAAFNAAGDGPRSTPTQGQT--QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
Y+ V A NAAG G S P+ +T +P P + ++ ++T++ + WE P F G
Sbjct: 8599 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGG 8658
Query: 1753 ILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEI 1812
G + Y + G ++ K VK++ EG Y+ R+ A
Sbjct: 8659 ---GEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSA--------- 8706
Query: 1813 EANVTTGPGEGAPG------------PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860
GEG PG PP V + V I I GK V+
Sbjct: 8707 ----VNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIM-----AGKTLRIPAVVT 8757
Query: 1861 ARPSDEGLW 1869
RP +W
Sbjct: 8758 GRPVPTKVW 8766
Score = 189 bits (481), Expect = 2e-47
Identities = 331/1484 (22%), Positives = 562/1484 (37%), Gaps = 198/1484 (13%)
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTY 473
G S+ L G P P + W K G ++ + S SL++ + D+G Y
Sbjct: 16585 GGSLRLFVPIKGRPTPEVKWGK-----VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKY 16639
Query: 474 TCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTI------ 527
T NS G A + V PP + V + T+ S+ +T +P +
Sbjct: 16640 TLTLENSSGTKSAFVTVRV---LDTPSPPVNLKVTEITKDSV--SITWEPPLLDGGSKIK 16694
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAH 583
YI EK AT + + +N S I Q G +Y RV + G +++A
Sbjct: 16695 NYIVEKREATRKSYAAVVTNCHKN-SWKIDQLQEGC--SYYFRVTAENEYGIGLPAQTAD 16751
Query: 584 -LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
++V ++P P T+ V R +++L+WTKP DG S +I+YI+EM ++ A
Sbjct: 16752 PIKVAEVPQPPGK--ITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16809
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ--------FSKDTERVSLPEEPPTAP 693
V K+ + L Y FR+ AVN+ G+ +KD V P+ P
Sbjct: 16810 RV--KSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL--VIEPDVKPAFS 16865
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK-NITDADVNNL 752
+V + I +P P I + GLP+ + N+TD+ L
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPT-----------ITWTKDGLPLKQTTRINVTDS----L 16910
Query: 753 LLEDLIIWTNYEIEVAAYNSAGLGVYSSKVT--EWTLQGVPTVPPGNVHAEATNSTTIRF 810
L L I ++ + Y V K E P P G V + ++ +I
Sbjct: 16911 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITL 16970
Query: 811 TWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTS 870
+WN P G ++ + ++ + T V + + V+ LK TEY
Sbjct: 16971 SWNPPL------YTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFR 17024
Query: 871 VLCFTTPGDG--PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTG 927
+ G S P + + PGP G + I S+ + W EP G + G
Sbjct: 17025 IFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 17084
Query: 928 YRISWEEYN-----RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAS 982
Y + +E N + N + H +++ L Y V A G G+ S +
Sbjct: 17085 YHLERKERNSILWTKVNKTIIH-----DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17139
Query: 983 T--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGE 1039
+ + P + PG P + + +TLQ+ +P YDG + I+ ++VE + G
Sbjct: 17140 SECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWM 17196
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
+ + + + V L Y FR+ N G S+PS + A ++
Sbjct: 17197 KASFTNVIETQ-----FTVSGLTEDQRYEFRVIAKNAAGAI--SKPSDSTGPITAKDEVE 17249
Query: 1100 PANVSLR---------TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKT 1147
+S+ A ET + PLP +E+ + + + + K
Sbjct: 17250 LPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKA 17309
Query: 1148 LSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVS 1207
L +V+D + D + ++A N GS + V R P GP V+
Sbjct: 17310 LL-IVKDAIRIDGG----------QYILRASNVAGSKSFPVNVKVLDRPG-PPEGPVQVT 17357
Query: 1208 ALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS--SRSAQLTG 1265
+ TS + WS P G + + V+ K +T W V + + S ++T
Sbjct: 17358 GV--TSEKCSLTWS--PPLQDGGSDISHYVVEKR---ETSRLAWTVVASEVVTNSLKVTK 17410
Query: 1266 LGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
L + Y +++A + G G P P+L + +PGPP + + S+ + W P
Sbjct: 17411 LLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRP 17470
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
+ G + I + + + + + TGL + Y FR++A+ G G
Sbjct: 17471 DSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 17530
Query: 1385 EAAEALVV--TTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRE 1441
E + A V + +P PP+ + D S+ L+W +P DG S + Y ++ +
Sbjct: 17531 EPSPATVYYKACDPVFKPGPPTNAHIV--DTTKNSITLAWGKPIYDGGSEILGYVVEICK 17588
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
W + + + F + +L YK RV A N +G E + S T
Sbjct: 17589 ADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTVKPEDK 17646
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
EAP L + +++R A I +G P
Sbjct: 17647 LEAPE-LDLDSELRKGIVVRAGGSARIHI----------------------PFKGRPTPE 17683
Query: 1562 ATWAELTSMYS--MRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
TW+ ++ ++ + TQ +DN +++ + + + N+ G S V V
Sbjct: 17684 ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG----SKSAFVTVK 17739
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR---GNLTERVK 1676
P+N+ V + WEPP +D ++ Y I E+ R N++ +
Sbjct: 17740 VLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDG-GAKVKNYVIDKRESTRKAYANVSSK-- 17796
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELT 1736
++ S K++NLT Y V A N G G PS P V ++++
Sbjct: 17797 ---CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17853
Query: 1737 TTSVNVSWEAPQFPNGI-LEGYRLVYEPCS----PVDGVSKIVTVDVKGNSPLWLKVKDL 1791
TS ++ WE P+ G + GY + +P + SK+ V G L
Sbjct: 17854 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTG----------L 17903
Query: 1792 AEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
+ G Y+FR++A Y + G+ P GVP+I +
Sbjct: 17904 SSGQEYQFRVKA----YNEK---------GKSDPRVLGVPVIAK 17934
Score = 189 bits (479), Expect = 3e-47
Identities = 429/1885 (22%), Positives = 716/1885 (37%), Gaps = 273/1885 (14%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAGR 180
V GE I P + P P V+W +DG+++ S R+ + ++ L + +V DAG
Sbjct: 8026 VIEGEKLSIPVP-FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGI 8084
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN 240
Y + N K G S I + V + GP I K + + + ++T E
Sbjct: 8085 YTITLEN-KLGSATAS--INVKVIGLPGPCKDI--------KASDITKSSCKLTWEPPEF 8133
Query: 241 ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVL-------RSSSV 293
LH + ++ + RR IP +G + + + ++ R +V
Sbjct: 8134 DGGTPILHYVLER---------REAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8184
Query: 294 PSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW----YKDAAVV 349
V G Y+ L+ P ++P++ + VD+ +ITW Y + +
Sbjct: 8185 NKVGGGEYIE-LKNPVIAQDPKQ----PPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8239
Query: 350 E---VEKLTRFRQR----NDGGLQI-----SGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
+EK+ + +R N+ + I GL F+ A NAAG + S
Sbjct: 8240 MGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPP 8299
Query: 398 TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLES 457
T I D V+L R ++ ++G+ I S+ S
Sbjct: 8300 TKAVDPI----------DAPKVIL--------RTSLEVKRGDEIALDASI---------S 8332
Query: 458 GSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVC 517
GS + T I D + + +A LV + + + ++ V+ TQ
Sbjct: 8333 GSPYPTITWIKDENVIV-----PEEIKKRAAPLVRRRKGEVQE--EEPFVLPLTQ----- 8380
Query: 518 GVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGN 577
R++I D + G ES R+R + D G Y +V + G
Sbjct: 8381 ------RLSI------DNSKKG-ESQLRVR----------DSLRPDHGLYMIKVENDHGI 8417
Query: 578 DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP- 635
+ V P P + V + + ++ W P D G S +I Y LE + P
Sbjct: 8418 AKAPCTVSVLDTPGPPINFV--FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPD 8475
Query: 636 --WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL-PEEPPTA 692
W V+ +++ SVT L+ + Y FR+ A N G G V+ P PP A
Sbjct: 8476 SEWIVVTSTLRHCKYSVTK--LIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8533
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNL 752
P + ++ +N S++++W P + NG I+ Y L V + + + N
Sbjct: 8534 PDKPIVEDVTSN-SMLVKWNEPKD---NG---SPILGYWLEKREVNSTHWSRVNKSLLNA 8586
Query: 753 L---LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV--HAEATNSTT 807
L ++ L+ Y V A N+AG G +S T P PPG T+STT
Sbjct: 8587 LKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTT 8645
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTAR-PNFQDSIHVGFVSGLKKFTE 866
I W P+ N G +++ + +++ T +R + V +++ +
Sbjct: 8646 IELEWEPPA------FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGAD 8699
Query: 867 YFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKN---- 922
Y V G+GP Q V E P L D S+K Q K
Sbjct: 8700 YKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVEL------DVSVKGGIQIMAGKTLRIP 8753
Query: 923 GILTGYRIS---W--EEYNRTNTRVTHYLPNVTLEYRVTGLTALTT-YTIEVAAMTSKGQ 976
++TG + W EE RV + NV + + AL + V T+
Sbjct: 8754 AVVTGRPVPTKVWTKEEGELDKDRVV--IDNVGTKSELIIKDALRKDHGRYVITATNSCG 8811
Query: 977 GQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVV 1035
+ +A+ + ++PGP +L + L + P DG + I+ +++E + +
Sbjct: 8812 SKFAAARVEVF---DVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 8868
Query: 1036 GEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP 1095
+ + E + ++ L Y FR+ N G PP + +
Sbjct: 8869 HTWRQPI-------ETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLG 8921
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
P +P ++ +++++ L W E NG GY I+ R H K V R
Sbjct: 8922 PPTSPERLTYTERTKSTITLDWK---EPRSNGGSPIQGYIIEKRR---HDKPDFERVNKR 8975
Query: 1156 V--ERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGPTNVSALATT 1212
+ + +E+L+E Y +V+A N IG S P V + VP PT L+
Sbjct: 8976 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP---PTIKLRLSVR 9032
Query: 1213 SSSMLVRWSE---VPEADRNGLVLGYKVMYKEKDSDTQPR--FWLVEGNSSRSAQLTGLG 1267
++ V+ E +P AD GL + K + +P + + SRS T L
Sbjct: 9033 GDTIKVKAGEPVHIP-ADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 9091
Query: 1268 --KYVLYE---VQVLAFTRIGDGSPS-HPPILERTLDDVPGPPMGILFPEVRTTSVRLIW 1321
K V + V A R+G + H + +R P PP + +++ S L W
Sbjct: 9092 IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDR-----PSPPRNLAVTDIKAESCYLTW 9146
Query: 1322 QPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA-RQYTATGLKPESVYLFRITAQTR 1380
P G + + + + + + EV + ++Y L P Y FR+ A +
Sbjct: 9147 DAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNK 9206
Query: 1381 KGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQ 1438
G + ++ VV + P PP +P V S+L+SW P D G SP+ Y ++
Sbjct: 9207 YGISDECKSDKVVIQDPYRLPGPPGKPKVLART--KGSMLVSWTPPLDNGGSPITGYWLE 9264
Query: 1439 TRELPSGRWALHSAS----VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE-S 1493
RE S W+ S + V F V RL Y+FR A N G SE S+
Sbjct: 9265 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPE 9324
Query: 1494 LTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT 1553
+ P P+ V T +S+ + W+PPA+D + I G+ + +E EG +
Sbjct: 9325 VAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIK-GYIVEMQE---EGTTDW- 9379
Query: 1554 LRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSP 1612
+ +N P + + NL + R+Y R+ N GE PS
Sbjct: 9380 -KRVNEPDKLITTCECV---------------VPNLKELRKYRFRVKAVNEAGESEPSDT 9423
Query: 1613 PQEVFVGEA-------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
E+ + + A +V + ++ + P + + G +
Sbjct: 9424 TGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMK 9483
Query: 1666 AQRGNLTERVKTLFLAENSVKL------KNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQT 1719
++ E + L AENS + ++ TG S+ A N AG + T
Sbjct: 9484 DGVHDIPEDAQ-LETAENSSVIIIPECKRSHTG----KYSITAKNKAG---QKTANCRVK 9535
Query: 1720 QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDV 1778
P P +K S++T S +SW+ P G ++GY + +DG +
Sbjct: 9536 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT---IDGKAWTKVNPD 9592
Query: 1779 KGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEA-NVTTGPGEGAPGPPGVPIIVRY 1836
G++ V DL Y FR+RA+ F GP +E TT P P + + +
Sbjct: 9593 CGSTTF--VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9650
Query: 1837 SSAIAIHWSSGDP---GKGPITRYVIEARPSD-----EGLWDILIKDIPKEVSSYTFSMD 1888
+ +H S P G P+T Y++E D + W K ++V F+++
Sbjct: 9651 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK---RDVEELQFTVE 9707
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSS 1913
L G Y+FRV AVN G PS+
Sbjct: 9708 DLVEGGEYEFRVKAVNAAGVSKPSA 9732
Score = 187 bits (474), Expect = 1e-46
Identities = 315/1447 (21%), Positives = 553/1447 (38%), Gaps = 151/1447 (10%)
Query: 524 RVTIRYIWEKDGATLGTESHPRIRLDRNGSL-HISQTWSGDIGTYTCRVISAGGNDSRSA 582
R T W KD L + N SL I D+G Y ++ ++ G +
Sbjct: 15802 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL 15861
Query: 583 HLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLL 640
++ V P P PV + V +I L+W P +DG S + YI+E + + W ++
Sbjct: 15862 NVIVLDKPGPPTGPVK-MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15920
Query: 641 ASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIAS 700
A+V T++ L YQFR+ A N GK + V+ PP + +
Sbjct: 15921 ATV--ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 15978
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIW 760
+ S+ +QW P + ++ ++ R + + N T L
Sbjct: 15979 LSSRDSMEVQWNEPISDGGSRVIGYHLERK--ERNSILWVKLNKTPIPQTKFKTTGLEEG 16036
Query: 761 TNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFI 820
YE V+A N G+G SKV+E + P PPG A ++ W P+
Sbjct: 16037 VEYEFRVSAENIVGIGK-PSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPT---- 16091
Query: 821 NGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG- 878
+ G K+ + E++E + +F + I F V+GL + Y V+ G
Sbjct: 16092 --YDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 16149
Query: 879 -DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNR 937
P + + ++V P +S ++ V E + + + G I ++ +
Sbjct: 16150 FSEPSESTGAITARDEVDPP--RISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK 16207
Query: 938 TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL----- 992
+ +++ T + T+ +++ A G + A ++ +
Sbjct: 16208 GDQELSN-----TARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 16262
Query: 993 --PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP + IS + TL ++P DG + I ++VE + L+ +
Sbjct: 16263 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRE------TSRLVWTVVD 16316
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTA 1108
S +V L Y+FR+ VN G P + + AP + T
Sbjct: 16317 ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV 16376
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLE 1166
++ S+ + W +G E +GY ++ +G T H R+ E + L
Sbjct: 16377 TKDSMIVVW---ERPASDGGSEILGYVLEKRDKEGIRWTRCH---KRLIGELRLRVTGLI 16430
Query: 1167 EWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLVRWSEVP 1224
E +Y +V A NA G S P + + + + GP N + T SS+ + WS+ P
Sbjct: 16431 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK-P 16489
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV----EGNSSRSAQLTGLGKYVLYEVQVLAFT 1280
D + GY V + D W + G + + ++ L + Y ++ A
Sbjct: 16490 IYDGGCEIQGYIV----EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16545
Query: 1281 RIGDGSPSHPP---ILERTLDDVPGPPMGILFPEVRTT----SVRLIWQPPAAPNGIILA 1333
+ G G + P I+E L+ P + + ++ S+RL P +
Sbjct: 16546 KAGVGEHADVPGPIIVEEKLE-APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 16604
Query: 1334 YQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY---LFRITAQTRKGWGEAAEAL 1390
++ + + A ++V + +T+ L + Y + +T + G ++
Sbjct: 16605 GKVDGEIR----DAAIIDVTS----SFTSLVLDNVNRYDSGKYTLTLENSSG----TKSA 16652
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
VT D P PP V + + SV ++WEP DG S ++ Y ++ RE +A
Sbjct: 16653 FVTVRVLDTPSPPVNLKVTE--ITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16710
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
+ N S+ +D+L+ SY FRV A N+ G ++ ++ + + + P ++
Sbjct: 16711 VVTNCHKN--SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVP--QPPGKIT 16766
Query: 1510 VTPHTTTSVLIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE 1566
V T SV + W P D KI ++ + ++ E W+E
Sbjct: 16767 VDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-------------------KWSE 16807
Query: 1567 LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-------PSSPPQEVFVG 1619
+ S+ Q + NL + Y R+ N G P V
Sbjct: 16808 CARVKSL---------QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 16858
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF 1679
+ P + +V V ++ ++ P P + D K + R N+T+ +L
Sbjct: 16859 DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK----QTTRINVTD---SLD 16911
Query: 1680 LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTS 1739
L S+K + Y ++VA N G S + P P VKF +++ S
Sbjct: 16912 LTTLSIKETHKDDGGQYGITVA--NVVGQKTASIEIVTLDKPDPPKGP--VKFDDVSAES 16967
Query: 1740 VNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1799
+ +SW P + G + + + V +V+ V + LKV L G Y+F
Sbjct: 16968 ITLSWNPPLYTGGC-QITNYIVQKRDTTTTVWDVVSATVARTT---LKVTKLKTGTEYQF 17023
Query: 1800 RIRAKTF---TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGKGPI 1854
RI A+ ++ E + V P + PGPPG P S ++ I W + G P+
Sbjct: 17024 RIFAENRYGQSFALESDPIVAQYPYK-EPGPPGTPFATAISKDSMVIQWHEPVNNGGSPV 17082
Query: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSP 1914
Y +E + + LW + K I + F L+ G+ Y+FRV A N G G S
Sbjct: 17083 IGYHLERKERNSILWTKVNKTI---IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17139
Query: 1915 SQSVPAQ 1921
S+ A+
Sbjct: 17140 SECYVAR 17146
Score = 177 bits (449), Expect = 1e-43
Identities = 352/1605 (21%), Positives = 600/1605 (37%), Gaps = 162/1605 (10%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP-------LDSTVI--DGM 417
+SGL D F+ A+NAAG + + + + P TVI G
Sbjct: 15046 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 15105
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ L + SG P P + W K + L G+ +L S +L+ + D+G YT A
Sbjct: 15106 AFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 15164
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP-------RVTIRYI 530
TN G + ++ V R PP+ + S C ++ P ++ +
Sbjct: 15165 TNPGGFAKHIFNVKVLDRPG---PPEGPLAVTEV-TSEKCVLSWFPPLDDGGAKIDHYIV 15220
Query: 531 WEKDGATLG-TESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA---GGNDSRSAHLRV 586
+++ + L T +++ + L +++ G+ Y RV++ G + + +
Sbjct: 15221 QKRETSRLAWTNVASEVQVTK---LKVTKLLKGN--EYIFRVMAVNKYGVGEPLESEPVL 15275
Query: 587 RQLPHAPEHPVAT--LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
P+ P P ++T+ + ++ + W P DG S +I YI+E + +
Sbjct: 15276 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15335
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVG------KGQFSKDTERVSLPEEPPTAPPQNV 697
V GL Y+FR+ A N G F K + V P PP N
Sbjct: 15336 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKP-----GPPGNP 15390
Query: 698 IASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA---DVNNLLL 754
+ SI I W P + I GY++ L P +++ +T + +
Sbjct: 15391 RVLDTSRSSISIAWNKPIYDGGSEIT-GYMVEIAL---PEEDEWQIVTPPAGLKATSYTI 15446
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
L Y+I + A NS GLG + T + + P + +A +
Sbjct: 15447 TGLTENQEYKIRIYAMNSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACC 15504
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT--EYFTSVL 872
F+ + + W + E + + ++ + V + +F +Y +V
Sbjct: 15505 TLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI--VGNVNRFDSGKYILTV- 15561
Query: 873 CFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS 931
G +S VR D PGP L E+ TS+ ++W P G + Y +
Sbjct: 15562 ---ENSSGSKSAFVNVRVL-DTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE 15617
Query: 932 WEEYNR-------TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
E R TN T ++V L +Y V A G G + A T
Sbjct: 15618 KRESTRKAYSTVATNCHKT--------SWKVDQLQEGCSYYFRVLAENEYGIG-LPAETA 15668
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
S E P PP + + ++ SV+L + +P +DG + I ++VE Q ++W
Sbjct: 15669 ESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQ---TKGSDKWAT 15725
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPA 1101
+ + L YSFR+ N G S P Q S + + L PP
Sbjct: 15726 CATVK----VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLL 15781
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD-- 1159
+ + L + ++ + G P + + + + K + V + E +
Sbjct: 15782 FNTFTVLAGEDLKV------DVPFIGRPTPA---VTWHKDNVPLKQTTRVNAESTENNSL 15832
Query: 1160 YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR 1219
TI+D V+ N+ G + V+ + P +GP + + T+ S+ +
Sbjct: 15833 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG-PPTGPVKMDEV--TADSITLS 15889
Query: 1220 WSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYVLYEVQVLA 1278
W P+ D + Y V EK + + +V +R+ + L Y+ ++ A
Sbjct: 15890 WGP-PKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAA 15945
Query: 1279 FTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQ 1335
R G + S P + + VPGPP + S+ + W P + G ++ Y
Sbjct: 15946 ENRYGKSTYLNSEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYH 16004
Query: 1336 ITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTE 1395
+ + + + P + + TGL+ Y FR++A+ G G+ ++
Sbjct: 16005 LERKERNSILWVKLNKTPIPQTK-FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYV- 16062
Query: 1396 KRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASV 1454
RD PP RP + V SV L W +P DG S + Y ++ +ELP GRW + ++
Sbjct: 16063 ARDPCDPPGRP--EAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRW-MKASFT 16119
Query: 1455 SHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHT 1514
+ + F V L Y+FRV A N G FSE SES + A + P +S+ P
Sbjct: 16120 NIIDTHFEVTGLVEDHRYEFRVIARNAAG--VFSEPSESTGAITARDEVDPPRISMDPKY 16177
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-FTLRGINNPGATWAELTSMYSM 1573
++++ K++ + G I + ++G L + + S+
Sbjct: 16178 KDTIVV--HAGESFKVDADIYGKPIP----TIQWIKGDQELSNTARLEIKSTDFATSLSV 16231
Query: 1574 RNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVH 1633
++ R Y L N + ++V GP P VV+
Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGP----------------VVIS 16275
Query: 1634 GATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGY 1693
G TA + + W+ PPL DI Y + E R L V + S K+ L
Sbjct: 16276 GVTAEKCTLAWK-PPLQDGGSDIINYIVERRETSR--LVWTVVDANVQTLSCKVTKLLEG 16332
Query: 1694 TAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPN 1751
Y + A N G G S P + P AP + + + +T S+ V WE P
Sbjct: 16333 NEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDG 16392
Query: 1752 GI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT--- 1807
G + GY L + + + L L+V L E Y FR+ A+
Sbjct: 16393 GSEILGYVLEKRDKEGI----RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLS 16448
Query: 1808 -YGPEIEANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPS 1864
P P PGPP P ++ + S++ + WS G I Y++E
Sbjct: 16449 EPSPPSAYQKACDP-IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 16507
Query: 1865 DEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G W + P ++ ++ L Y+FR+ A+N G G
Sbjct: 16508 SVGEWTMCTP--PTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16550
Score = 177 bits (449), Expect = 1e-43
Identities = 292/1333 (21%), Positives = 502/1333 (37%), Gaps = 167/1333 (12%)
Query: 647 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGR-TNQ 705
+T++ K S + L A N G F+K V + + P PP+ +A T++
Sbjct: 15144 STNLVNKDSTRRDSGAYTLTATNP---GGFAKHIFNVKVLDRP--GPPEGPLAVTEVTSE 15198
Query: 706 SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNNLLLEDLIIWTNYE 764
++ W PP + + YI++ + N+ ++ V L + L+ Y
Sbjct: 15199 KCVLSWFPPLDDG-GAKIDHYIVQKRETSR---LAWTNVASEVQVTKLKVTKLLKGNEYI 15254
Query: 765 IEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFING 822
V A N G+G + S V G P PP N ++ W P
Sbjct: 15255 FRVMAVNKYGVGEPLESEPVLAVNPYGPPD-PPKNPEVTTITKDSMVVCWGHPDS----- 15308
Query: 823 INQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-DG 880
+ G ++I + E+ ++ + N + + + VSGL + EY ++ G
Sbjct: 15309 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15367
Query: 881 PRSTPQLVRTHEDV--PGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR 937
P T + + V PGP G+ + +S+ ++W +P G +TGY +
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15427
Query: 938 TNTRVTHYLPNVTLE---YRVTGLTALTTYTIEVAAMTSKGQGQVSA-----STISSGVP 989
++ P L+ Y +TGLT Y I + AM S+G G+ + +P
Sbjct: 15428 DEWQIV--TPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 15485
Query: 990 PELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
PE+ + I F P +W + GE + I S+
Sbjct: 15486 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH-----GESLDKASIESTSS 15540
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
+ V ++N F + + N G+ R + T P D+ ++ +
Sbjct: 15541 YT---LLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDL-----KVKEVT 15592
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
+TS+ L W P P ++ G + Y ++ + + K S V + + + ++ L+E
Sbjct: 15593 KTSVTLTWDP-PLLD--GGSKIKNYIVE--KRESTRKAYSTVATNCHKTSWKVDQLQEGC 15647
Query: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSG----PTNVSALATTSSSMLVRWSEVPE 1225
Y +V A N G G + T ESV +S P ++ + T +S+ + W E PE
Sbjct: 15648 SYYFRVLAENEYGIG-----LPAETAESVKASERPLPPGKITLMDVTRNSVSLSW-EKPE 15701
Query: 1226 ADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDG 1285
D +LGY V + K SD V+ A +TGL + Y +V A G
Sbjct: 15702 HDGGSRILGYIVEMQTKGSDKWATCATVKVTE---ATITGLIQGEEYSFRVSAQNEKGIS 15758
Query: 1286 SPSH------------PP---ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
P PP +L T + G + + P + + + W P
Sbjct: 15759 DPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVP--- 15815
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ T R+N + ++ + + R+ Y+ ++T GEA E L
Sbjct: 15816 ---LKQTTRVNAESTENNSLLTIKDACREDVGH-------YVVKLTNSA----GEAIETL 15861
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
V D+P PP+ P V+ ++V A S+ LSW P DG S + Y ++ R+ + W +
Sbjct: 15862 NVIV--LDKPGPPTGP-VKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQI 15918
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
SA+V+ ++ RLK Y+FR+ A N G S + ++ P
Sbjct: 15919 VSATVAR--TTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV 15976
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + S+ ++W P D + ++ G+ L W +L
Sbjct: 15977 VTLSSRDSMEVQWNEPISDGGSRVI----------------GYHLERKERNSILWVKL-- 16018
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE--AVPTAAP 1627
N + T+++ L + YE R+S N VG G S E +V P P
Sbjct: 16019 -----NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRP 16073
Query: 1628 RNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKL 1687
++V T + + W+ P D I GY + E G + T + + ++
Sbjct: 16074 EAIIV---TRNSVTLQWKKPTYDG-GSKITGYIVEKKELPEGRWMKASFTNII-DTHFEV 16128
Query: 1688 KNLTGYTAYMVSVAAFNAAGDGPRSTPTQG----QTQQAAPSAPSSVKFSELTTTSVNVS 1743
L Y V A NAAG + + G + + P K+ + S
Sbjct: 16129 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 16188
Query: 1744 WEAPQFPNGILEGYRLVYEPCSPVDGV------SKIVTVDVKGNS-PLWLKVKDLAEGVT 1796
++ G +P + + S +++K L VKD +
Sbjct: 16189 FKVDADIYG---------KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16239
Query: 1797 YRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGKGP 1853
+ ++AK + NV PGPP P+++ +A + W G
Sbjct: 16240 GNYILKAKNVAGERSVTVNVKV---LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSD 16296
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSS 1913
I Y++E R + +W + + V + + + L G Y FR++AVN YG G
Sbjct: 16297 IINYIVERRETSRLVWTV----VDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG---E 16349
Query: 1914 PSQSVPAQKANPF 1926
P +S P NPF
Sbjct: 16350 PLESEPVVAKNPF 16362
Score = 171 bits (433), Expect = 7e-42
Identities = 352/1639 (21%), Positives = 604/1639 (36%), Gaps = 203/1639 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL--------DSTVIDGM 417
+++ L D F+ FARNAA V + I + P D V+
Sbjct: 19373 EVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAG 19432
Query: 418 SVV-LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ + + +G P P I+W K + I + + L + D G Y
Sbjct: 19433 EVLKINADIAGRPLPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19491
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
N G + + V + PP I G A C ++ W +
Sbjct: 19492 LKNVAGTRSVAVNCKVLDKPG---PPAGPLEINGLTAEK-CSLS----------WGRPQE 19537
Query: 537 TLGTESHPRIRLDRNGSLHISQT-WSGDIGTYTCRVIS-----------------AGGND 578
G + I +++ + H++ T G++ +C+V G
Sbjct: 19538 DGGADIDYYI-VEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19596
Query: 579 SRSAHLRVRQLPHAPEHPVAT-LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPW 636
S ++ P P + +++V + ++ L W++P DG S + YI+E E N+
Sbjct: 19597 LESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLR 19656
Query: 637 TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT------ERVSLPEEPP 690
V + V GL Y++R+ A N G S+ + + V LP PP
Sbjct: 19657 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPS-PP 19715
Query: 691 TAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
+ P ++ SG+T +I I W P + GY + Y K D D
Sbjct: 19716 SKP--KIVDSGKT--TITIAWVKPLFDG-GAPITGYTVEY-----------KKSDDTDWK 19759
Query: 751 NLL---------LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAE 801
+ + L Y V + N G S + P ++ +E
Sbjct: 19760 TSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 19819
Query: 802 ATNSTTIR----FTWNAPS-----PQFI-NGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851
+ ++ FT P P + + + + A+ + ++ N D
Sbjct: 19820 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRND 19879
Query: 852 SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
S K+T +VL ++ LV D PGP +++ ++ S
Sbjct: 19880 S---------GKYTLTIQNVLS--------AASLTLVVKVLDTPGPPTNITVQDVTKESA 19922
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTN-TRVTHYLPNVTLEYRVTGLTALTTYTIEVA 969
+SW P G + Y I E ++ VT+ L Y+VT L Y V+
Sbjct: 19923 VLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNR--LSYKVTNLQEGAIYYFRVS 19980
Query: 970 AMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLV 1028
G G + A T E P PP LG+++I SV+L + +P +DG + I ++V
Sbjct: 19981 GENEFGVG-IPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVV 20039
Query: 1029 EAQVGVVGEGEE-WLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSR 1087
EA + +G++ W+ + V L + Y FR+ N G S P +
Sbjct: 20040 EA----LEKGQKNWVKCAVAKSTHHV----VSGLRENSEYFFRVFAENQAGLSDPRE--- 20088
Query: 1088 KIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY--NGNPESVGYKIKYSRSDGHG 1145
+ + + P + ++ ++++R +++ +G P K+ SR
Sbjct: 20089 LLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLP---KVTLSRDGVPL 20145
Query: 1146 KTLSHVVQDRVERDYTIEDLEEWTEY--RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP 1203
K + + TI E T R ++ A N+ G+ +V R P +GP
Sbjct: 20146 KATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG-PPTGP 20204
Query: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 1263
+S + T S+ ++W E P+ D V Y ++ +E + +
Sbjct: 20205 VVISDI--TEESVTLKW-EPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 20261
Query: 1264 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD-DVPGPPMGILFPEVRTTSVRLIWQ 1322
G+ Y+ ++ A R G + L PGPP V S+ + W
Sbjct: 20262 LTTGEE--YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWH 20319
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
P + G + + + L + T + +Y FR+ A+ G
Sbjct: 20320 EPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAG 20379
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRE 1441
G+ + D +PP V+ D+ SV LSW+ P DG S + Y ++ R+
Sbjct: 20380 VGKPSHPSEPVLAI-DACEPPRN--VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRD 20436
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
LP GRW S + + + FI+ L + Y+FRV A N +G S SE + +
Sbjct: 20437 LPDGRWTKASFT-NVTETQFIISGLTQNSQYEFRVFARNAVGS--ISNPSEVVGPITCID 20493
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
++ + P T V ++YR LR + G P
Sbjct: 20494 SYGGPVIDL-PLEYTEV--------------------VKYRAGTSVKLRA-GISGKPAPT 20531
Query: 1562 ATW------AELTSMYSMRNLSR-PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ 1614
W + ++ + N + S+ + D LN YE+++ NA+G ++
Sbjct: 20532 IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-YELKLR--NAMGSASATIRV 20588
Query: 1615 EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTER 1674
++ + + P P + TA ++ + W PP D G KI + ++ +
Sbjct: 20589 QI-LDKPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITHYIVEKRETSRV 20639
Query: 1675 VKTLF---LAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSS 1729
V ++ L E + + Y+ V A N G G S + P P
Sbjct: 20640 VWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 20699
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ +++T S+ V W P G + GY L + G K++ ++ KV
Sbjct: 20700 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIRDTRQ---KV 20755
Query: 1789 KDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGPPGVPIIVRYS----SAIAIH 1843
L E Y++R+ A GP E + + PPG P +R + S+I +
Sbjct: 20756 TGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID-PPGPPAKIRIADSTKSSITLG 20814
Query: 1844 WSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
WS G +T YV+E R +E W + EV + + + LKPGV+Y FRV A
Sbjct: 20815 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTV--STKGEVRTTEYVVSNLKPGVNYYFRVSA 20872
Query: 1903 VNDYGFGTPSSPSQSVPAQ 1921
VN G G P ++ V A+
Sbjct: 20873 VNCAGQGEPIEMNEPVQAK 20891
Score = 167 bits (423), Expect = 1e-40
Identities = 305/1309 (23%), Positives = 495/1309 (37%), Gaps = 158/1309 (12%)
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+++ + P PE T ++ + +++LTW KP DG S ++ Y++E E V A
Sbjct: 19997 VKITEKPSPPEKLGVT--SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAV 20054
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPE--EPPTAPPQN---- 696
K+T V GL Y FR+ A N G + V + E EPP +N
Sbjct: 20055 A--KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 20112
Query: 697 ---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLL 753
V A I I +P P+ + G+P+ + T+ NL
Sbjct: 20113 TVYVRAGSNLKVDIPISGKPLPK-----------VTLSRDGVPLKATMRFNTEITAENLT 20161
Query: 754 --LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
L++ + E+ A NS+G + G PT P V ++
Sbjct: 20162 INLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP---VVISDITEESVTLK 20218
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEE----EVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W P +G +Q I + E EV+ AR + V L EY
Sbjct: 20219 WEPPK---YDGGSQVTNYILLKRETSTAVWTEVSATVARTMMK-------VMKLTTGEEY 20268
Query: 868 FTSVLCFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
+ G D S V+ PGP + + S+ V W EP G
Sbjct: 20269 QFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSA 20328
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
+ GY + ++ N + + L T ++VT ++A Y V A + G G+ S +
Sbjct: 20329 VVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPS- 20387
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ + PP N+ I++I SV+L ++ P +DG + I+ ++VE + G +
Sbjct: 20388 EPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTK--- 20444
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQ---PSRKIQTLQAPPDMA 1099
+N + + + + L + Y FR+ N VG+ S PS+ P I + P
Sbjct: 20445 -ASFTNVTETQFI-ISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20502
Query: 1100 PANVS--LRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE 1157
P + ++ + TS+ LR +G P I++ + D +T + V +
Sbjct: 20503 PLEYTEVVKYRAGTSVKLR------AGISGKPAPT---IEWYKDDKELQTNALVCVENTT 20553
Query: 1158 --RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTV-VGRTRESVPSSGPTNVSALATTSS 1214
I+D + +++ NA+GS S T+ V + P GP +
Sbjct: 20554 DLASILIKDADRLNSGCYELKLRNAMGSA--SATIRVQILDKPGPPGGPIEFKTVTAEKI 20611
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTG--LGKYVLY 1272
++L R P AD G + + ++ K + S W + +T + K Y
Sbjct: 20612 TLLWR----PPADDGGAKITHYIVEKRETSRV---VWSMVSEHLEECIITTTKIIKGNEY 20664
Query: 1273 EVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI- 1330
+V A + G G P ++ + PGPP ++ S+ ++W P A G
Sbjct: 20665 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 20724
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA- 1389
I Y + R + ++ RQ TGL S Y +R+ A G G +E
Sbjct: 20725 ISGYFLEKRDKKSLGWFKVLKETIRDTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPS 20783
Query: 1390 -LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW 1447
+ D P PP++ ++ D S+ L W +P DG S V Y ++ R+ W
Sbjct: 20784 EFYKAADPIDPPGPPAK--IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEW 20841
Query: 1448 ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
S + ++V LKP +Y FRV A N G E E +E + EAP I
Sbjct: 20842 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL--EAPEI 20899
Query: 1508 LSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE- 1566
+ TSV+ + ED +L+ F +G P TW +
Sbjct: 20900 -DLDVALRTSVIAK---AGEDV--QVLIPF-----------------KGRPPPTVTWRKD 20936
Query: 1567 -----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEA 1621
+ YS+ N SL N +Y +++ N VGE P S V V +
Sbjct: 20937 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY--ILTIENGVGE-PKSSTVSVKVLD- 20992
Query: 1622 VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF-- 1679
P A + V H + T + + W+PP +D G I + ++ + T+R ++
Sbjct: 20993 TPAACQKLQVKHVSRGT-VTLLWDPPLIDG------GSPIINYVIEKRDATKRTWSVVSH 21045
Query: 1680 -LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ S KL +L+ T + V A N G G T+ P+ + + T T
Sbjct: 21046 KCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKT 21105
Query: 1739 SVNVSWEAPQFPNGILEGYRLVY-----EPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAE 1793
SV +SW P F G + +V E G+SK ++ V L E
Sbjct: 21106 SVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIE----------VSQLKE 21155
Query: 1794 GVTYRFRIRAKT-------FTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
FR+ AK T GP + P PG + VR
Sbjct: 21156 QSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR 21204
Score = 164 bits (414), Expect = 1e-39
Identities = 332/1511 (21%), Positives = 556/1511 (36%), Gaps = 169/1511 (11%)
Query: 473 YTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRY--- 529
+ A N +G+ + + + I P D S I G Q ++ G H+ + + Y
Sbjct: 21161 FRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIG--HNVHLELPYKGK 21218
Query: 530 -----IWEKDGATLGTESHPRIRLDRNG-SLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
W KDG L R N +L I G YT + +A +
Sbjct: 21219 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPIT 21278
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP-WTVLLA 641
+ P P+ P+ ++ ++ L+W P D G + Y +E E + W ++ +
Sbjct: 21279 VITLGPPSKPKGPIR-FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21337
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
SV T+ V LV YQFR+ A N G Q + V+ + PP +
Sbjct: 21338 SV--ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYN 21395
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T+ + + W P + + ++ + + +Q N + L+
Sbjct: 21396 VTSDGMSLTWDAPVYDGGSEVTGFHVEKK--ERNSILWQKVNTSPISGREYRATGLVEGL 21453
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
+Y+ V A NSAGL S +++TL P PPG TI WN P
Sbjct: 21454 DYQFRVYAENSAGLSSPSDP-SKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLR---- 21508
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-- 878
+ G K++ + E+ + R NF D + V+GL Y ++ G
Sbjct: 21509 --DGGSKIVGYSIEKRQGNER-WVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI 21565
Query: 879 DGPRSTPQLVRTHEDVPGPV---GHLSFSEIL---DTSLKVSWQEPGEKNGILTGYRISW 932
P + ++ T ++ P+ G F ++ SL++ G +T ++
Sbjct: 21566 SPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGV 21625
Query: 933 EEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R N +T L + +L R YT+E A + G + P ++
Sbjct: 21626 EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE--AKNASGSAKAEIKVKVQDTPGKV 21683
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
GP + +NI +TL + P DG I+ +++E + W LI ++
Sbjct: 21684 VGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRET---SRLAWALIE---DKC 21734
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1111
+A+S L Y FR+ VN G P + +Q AP +
Sbjct: 21735 EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGN 21794
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLEEWT 1169
S+ L W E +G E Y ++ R + V+ R E + + L E
Sbjct: 21795 SITLTWA---RPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRFKVTGLTEGN 21849
Query: 1170 EYRVQVQAFNAIGSGPWSQ-TVVGRTRESV-PSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
EY V A NA G GP S + + + RE V P PT V T+ +++ + WS+ P D
Sbjct: 21850 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK-PVFD 21908
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++GY + + D + E +T L Y+ +V A G G
Sbjct: 21909 GGMEIIGYIIEMCKADLGDWHKV-NAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDS 21967
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ-------ITHRL 1340
+ +D + P + I +T VR A + +AYQ + +
Sbjct: 21968 CEVTGTIKAVDRLTAPELDIDANFKQTHVVRA-----GASIRLFIAYQGRPTPTAVWSKP 22022
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + A + S T + +T + G ++++ T + D P
Sbjct: 22023 DSNLSLRADIHT-TDSFSTLTVENCNRNDAGKYTLTVENNSG----SKSITFTVKVLDTP 22077
Query: 1401 QPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP + +DV S L W+ P DG + + +Y ++ RE W + S +
Sbjct: 22078 GPPGP--ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI- 22134
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT-TLQAAPDEAPTILSVTPHTTTSV 1518
F V+ L Y FRV A N+ G E E E + T Q AP P L V + +S
Sbjct: 22135 -FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP---PRRLDVVDTSKSSA 22190
Query: 1519 LIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
++ W P D +I G LL R + + E G T +LT
Sbjct: 22191 VLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHT-----------KQLT------- 22230
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------PTA---- 1625
+ ++ L + YE R+ N G S P+E F + PTA
Sbjct: 22231 --------FTVERLVEKTEYEFRVKAKNDAGY---SEPREAFSSVIIKEPQIEPTADLTG 22279
Query: 1626 -APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE-RVKTLFLAEN 1683
+ + + +DV P ++ ++ E R ++T + +T ++
Sbjct: 22280 ITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK--ETDRVSITTTKDRTTLTVKD 22337
Query: 1684 SVK---------LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSE 1734
S++ L+N G + V+V G P G + ++ SA S V
Sbjct: 22338 SMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG------PVTGPIEVSSVSAESCV---- 22387
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+SW P+ G E + E ++V VK +KV L +
Sbjct: 22388 -------LSWGEPKDGGGT-EITNYIVEKRESGTTAWQLVNSSVKRTQ---IKVTHLTKY 22436
Query: 1795 VTYRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPG 1850
+ Y FR+ ++ F +E A + P P P + S+ A++I W G
Sbjct: 22437 MEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDG 22496
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
I Y +E + + LW +K+ + + L G+ Y FR A+N G
Sbjct: 22497 GSKIIGYWVEKKERNTILW---VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 22553
Query: 1911 PSSPSQSVPAQ 1921
S S+ + AQ
Sbjct: 22554 ASEASRPIMAQ 22564
Score = 161 bits (408), Expect = 6e-39
Identities = 283/1169 (24%), Positives = 437/1169 (37%), Gaps = 141/1169 (12%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLI-SPTHISDA 470
T+ G S+ L SG P P ITW K LAS ++ ES SLLI + DA
Sbjct: 23085 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI----IDTTESYSLLIVDKVNRYDA 23140
Query: 471 GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV----- 525
G YT A N G A+ + V+ T P +K V P +
Sbjct: 23141 GKYTIEAENQSGKKSATVLVKVYD----TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAP 23196
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVI-----SAGGNDSR 580
YI EK A + + + IS G + Y RV+ G
Sbjct: 23197 VNNYIVEKREAAMRAFKTVTTKCSKT-LYRISGLVEGTM--YYFRVLPENIYGIGEPCET 23253
Query: 581 SAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP-FDGNSPLIRYILEMSENNAPWT 637
S + V ++P P A L V+ + + L W KP +DG S L Y+LE +
Sbjct: 23254 SDAVLVSEVPLVP----AKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW 23309
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS------LPEEPPT 691
+ + ++ P TV L Y FR+ A N+ G + + V+ LP +
Sbjct: 23310 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23369
Query: 692 APPQNVI--ASGRTNQSIM-IQWQPPPESHQNGILKGYIIRYCLAG--LPVGYQFKNITD 746
PQ I +GR + ++ I +PPP + + AG L + T
Sbjct: 23370 TMPQKTIHVPAGRPVELVIPIAGRPPPAAS-----------WFFAGSKLRESERVTVETH 23418
Query: 747 ADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
V L + + I E + N G + KV G PT P + + ++T
Sbjct: 23419 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP---IKIDEIDAT 23475
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEE-------VTMVTARPNFQDSIHVGFVS 859
+I +W P ++ G L + EQ + V+ R F+ +
Sbjct: 23476 SITISWEPPE------LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFK-------FT 23522
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLV--RTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G G +++ R+ +PGP L ++ + ++W
Sbjct: 23523 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23582
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +TGY + +E + +P YR TGLT Y V A+ ++G
Sbjct: 23583 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23642
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVG 1033
G+ S + I + P PG P N +++ SV+L + P +G + ++ +L+E Q
Sbjct: 23643 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23702
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQT 1091
+ EW + + R + L Y FR+ N G P++ + K+
Sbjct: 23703 ---DQHEWTKCNTTPTK--IREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 23757
Query: 1092 LQAPPDMA-----PANVSLRTASETSLWL--RWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
+ PD + +R L + + P P ++ + + + + S+ H
Sbjct: 23758 MLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH 23817
Query: 1145 GKTLSHVVQDRVERDYTIEDL--EEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSS- 1201
+ V+++ D DL E + IGS P+S
Sbjct: 23818 TEL---VIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS---------------PNSP 23859
Query: 1202 -GPTNVSALATTSSSMLVRWSEVPEADRNGL-VLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
GP + S VR S P AD G +LGY + +E W + R
Sbjct: 23860 EGPLEYDDIQVRS----VRVSWRPPADDGGADILGYILERREVPKAA----WYTIDSRVR 23911
Query: 1260 SAQLT--GLGKYVLYEVQVLAFTRIGDGSP--SHPPILERTLDDVPGPPMGILFPEV--- 1312
L GL + V Y +V A + G P S P+ +T + P PP PEV
Sbjct: 23912 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP--PEVLDV 23969
Query: 1313 RTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+SV L W P G + R T+T + YT TGL P++ Y
Sbjct: 23970 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 24029
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGL 1429
FRI AQ G E + A VV + D+P P ++ + SV L WE P DG
Sbjct: 24030 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE--LEILSISKDSVTLQWEKPECDGG 24087
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+ Y ++ R+ W S F + L T Y+FRV A N+ G S
Sbjct: 24088 KEILGYWVEYRQSGDSAWK-KSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24146
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSV 1518
+ S+ T + EAP I TT +
Sbjct: 24147 TAMSIKT-KLTSGEAPGIRKEMKDVTTKL 24174
Score = 158 bits (400), Expect = 5e-38
Identities = 355/1546 (22%), Positives = 567/1546 (36%), Gaps = 189/1546 (12%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
G P P+I WYKD ++ L D + I ++G ++ RNA G +
Sbjct: 20526 GKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT 20585
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVL----ACETSGAPRPAITWQKGERILASGSVQ 448
+ + P GP++ + + L + GA +K E S+
Sbjct: 20586 IRVQILD-KPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMV 20644
Query: 449 LPRFTPLESGSLLISPTHISDAGTY--TCLATNSRGVDE-ASADLVVWARTRITK-PPQD 504
+I+ T I Y A N G+ E +D VV +T PP
Sbjct: 20645 SEHLE-----ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 20699
Query: 505 QSVIKGTQASMVCGVTH-----DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
V K T+ SM + ++ ++ ++D +LG + + T
Sbjct: 20700 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLT 20759
Query: 560 WSGDIGTYTCRVISAG-GNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
+ D C V +AG G S + P P P A + + + +I L W+KP
Sbjct: 20760 ENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPV 20819
Query: 616 FDGNSPLIRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S + Y++E+ + WT + + + T V L P +Y FR+ AVN G+G
Sbjct: 20820 YDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG 20879
Query: 675 QFSKDTERVSLPE--EPP-----TAPPQNVIASGRTNQSIMIQW--QPPPESHQNGILKG 725
+ + E V + E P A +VIA + ++I + +PPP K
Sbjct: 20880 EPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKN 20939
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
G Y +N D ++LL + + + + G+G S
Sbjct: 20940 -------LGSDARYSIEN---TDSSSLLTIPQVTRNDTGKYILTIEN-GVGEPKSSTVSV 20988
Query: 786 TLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTA 845
+ P + + + T+ W+ P I+ G +I + E+ + +
Sbjct: 20989 KVLDTPAACQ-KLQVKHVSRGTVTLLWDPPL------IDGGSPIINYVIEKRDATKRTWS 21041
Query: 846 RPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFS 904
+ + S + L + T +F VL G G P T + V+ E VP P+ LS
Sbjct: 21042 VVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE-VPAPIRDLSMK 21100
Query: 905 EILDTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTT 963
+ TS+ +SW +P G ++T Y + E + +H + T E V+ L +
Sbjct: 21101 DSTKTSVILSWTKPDFDGGSVITEYVV--ERKGKGEQTWSHAGISKTCEIEVSQLKEQSV 21158
Query: 964 YTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPG------Y 1017
V A KG TI EL P + +S+I VT++ Y
Sbjct: 21159 LEFRVFAKNEKGLS--DPVTIGPITVKELIITP-EVDLSDIPGAQVTVRIGHNVHLELPY 21215
Query: 1018 DGKTSIS-RW------LVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
GK S W L E++ + E + + + + + L+ C
Sbjct: 21216 KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRI-- 21273
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPE 1130
+ ++ PPS+P I+ + D S+ L W +P E NG E
Sbjct: 21274 AVPITVITLGPPSKPKGPIRFDEIKAD--------------SVILSW-DVP--EDNGGGE 21316
Query: 1131 SVGYKI-KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-S 1187
Y I K S + K + V + + +L + EY+ +V+A N G S P S
Sbjct: 21317 ITCYSIEKRETSQTNWKMVCSSV---ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21373
Query: 1188 QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS--- 1244
+V + + +P P TS M + W + P D V G+ V KE++S
Sbjct: 21374 SIIVAKHQFRIPGP-PGKPVIYNVTSDGMSLTW-DAPVYDGGSEVTGFHVEKKERNSILW 21431
Query: 1245 ---DTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD--D 1299
+T P S R + TGL + + Y+ +V A G SPS P + D
Sbjct: 21432 QKVNTSP-------ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVD 21484
Query: 1300 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSA 1357
PG P I +V ++ L W PP G I+ Y I R N +V S
Sbjct: 21485 PPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDV---SE 21538
Query: 1358 RQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARS 1417
QYT TGL P Y FRI A+ G RD P P+V+
Sbjct: 21539 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVP---PIVEFGPEYFDG 21595
Query: 1418 VLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY----- 1472
+++ G S +Q R +P W + + I D L + +
Sbjct: 21596 LII-----KSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT 21650
Query: 1473 -----KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAE 1527
+ V+A N G S ++E +Q P + + T T + + W P
Sbjct: 21651 RDHRGVYTVEAKNASG----SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLN 21706
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
D I + I RE WA + S T +L
Sbjct: 21707 DGCAPI-THYIIEKRE---------------TSRLAWALIED-----KCEAQSYTAIKLI 21745
Query: 1588 NLNKHRRYEIRMSVYNAVGEGP--SSPPQEVFVGEAVPTA----APRNVVVHGATATQLD 1641
N N+ Y+ R+S N G G S P + VP A P N+ T +
Sbjct: 21746 NGNE---YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNI-----TGNSIT 21797
Query: 1642 VTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVA 1701
+TW P D +IQ Y + E + + + ++E K+ LT Y V
Sbjct: 21798 LTWARPESDG-GSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVM 21856
Query: 1702 AFNAAGDGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGY 1757
A NAAG GP S + + + P P+ VK ++ + T+V++ W P F G+ + GY
Sbjct: 21857 AENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGY 21916
Query: 1758 RLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA 1803
+ E C + V+ + V DL G Y+FR+ A
Sbjct: 21917 --IIEMCKA--DLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSA 21958
Score = 158 bits (399), Expect = 6e-38
Identities = 319/1434 (22%), Positives = 534/1434 (37%), Gaps = 160/1434 (11%)
Query: 531 WEKDGATLGTESHPRIRLD-RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W KD A + + I+ +L + D G Y V ++ G+ + V
Sbjct: 10480 WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10539
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P PV+ V + + ++W P D G S + YI+E E + + S K T
Sbjct: 10540 PGPPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-T 10597
Query: 649 SVTVKGLVPARSYQFRLCAVNDVG-KGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
+ V L+ + Y FR+ A N G D+ + P AP Q ++ T S
Sbjct: 10598 TCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEV-TKDSA 10656
Query: 708 MIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNITDADVN---NLLLEDLIIWTNY 763
++ W P H G + YI+ + ++ +T ++ + DL+ Y
Sbjct: 10657 LVTWNKP---HDGGKPITNYILE---KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 10710
Query: 764 EIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
E V+A N G+G S SK PP N A T ++ TW P +
Sbjct: 10711 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10770
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG- 880
I GY ++ ++ +EE P V+GL+ Y VL G+
Sbjct: 10771 KI-LGY-IVEYQKVGDEEWRRANHTPESCPETKYK-VTGLRDGQTYKFRVLAVNAAGESD 10827
Query: 881 PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGY---RISWEEYNR 937
P P+ V + + P L + + +KV + + I+ G +++W++ +R
Sbjct: 10828 PAHVPEPVLVKDRLEPPELILDANMAREQHIKVG--DTLRLSAIIKGVPFPKVTWKKEDR 10885
Query: 938 ---TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGV-PPELP 993
T R+ LE R Y++ V + + T+S V + P
Sbjct: 10886 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLVLDKP 10938
Query: 994 GPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
GPP +L +S I S L ++ P DG + I+ ++VE + +W LS
Sbjct: 10939 GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVA---SAQW---SPLSATSK 10992
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ-APPDMAPANVSLRTASET 1111
+S LN Y FR+ N G P + + I+ L P P ++ +T
Sbjct: 10993 KKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKT 11052
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG----KTLSHVVQDRVERDYTIEDLEE 1167
+ L W + + +G GY ++Y KT++++ + + L++
Sbjct: 11053 EVSLVW---NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNL-------ECVVTGLQQ 11102
Query: 1168 WTEYRVQVQAFNAIGSGPWSQTVVGRTRES-VPSSGPTNVSAL--------ATTSSSMLV 1218
YR +V+A N +G G T+ +E VP S +V + T ++
Sbjct: 11103 GKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAII 11162
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
R VP A K + T + + N S + + E Q+
Sbjct: 11163 RGVPVPTA---------KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI-- 11211
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQIT 1337
+ + + S + T+ DVPGPP G I +V + + WQPP G + I
Sbjct: 11212 --TVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIV 11269
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEK 1396
+ T +T V S + L+ Y+FR+ A+ + G G ++ V K
Sbjct: 11270 EK-QDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHK 11328
Query: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
P PP +P+V D+ + +SW P SDG SP+ Y ++ RE+ +G+W + +
Sbjct: 11329 FSPPSPPGKPVV--TDITENAATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPI 11385
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHT 1514
+ F V L +Y+FRV A N G S+ S S+ + + P I + +
Sbjct: 11386 ADL-KFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS 11444
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMR 1574
+ + W P D + IL G+ + A W + +R
Sbjct: 11445 RETADLVWTKPLSDGGSPIL----------------GYVVECQKPGTAQWNRINKDELIR 11488
Query: 1575 NLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVVV 1632
+ + + L + Y R+ N VGEG E + + + P +V
Sbjct: 11489 QCA------FRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTC 11542
Query: 1633 HGATATQLDVTW----------EPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
++ T EP ++ G + R + ++ L E
Sbjct: 11543 RDVITVRVGQTIRILARVKGRPEPDITWTKEGKV---------LVREKRVDLIQDLPRVE 11593
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
+K + Y++S A N++G S + P ++K + +T + +
Sbjct: 11594 LQIKEAVRADHGKYIIS--AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKENCTI 11648
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIR 1802
SWE P NG E + E P IV DV + +K LA Y FR+
Sbjct: 11649 SWENP-LDNGGSEITNFIVEYRKPNQKGWSIVASDV---TKRLIKANLLANN-EYYFRVC 11703
Query: 1803 AKT-FTYGPEIEA-------NVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD-PGKGP 1853
A+ GP IE N PGE P + I + + + + W D G P
Sbjct: 11704 AENKVGVGPTIETKTPILAINPIDRPGE----PENLHIADKGKTFVYLKWRRPDYDGGSP 11759
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG 1907
Y +E R W+ + K KE + +D Y+FRV N+ G
Sbjct: 11760 NLSYHVERRLKGSDDWERVHKGSIKETH---YMVDRCVENQIYEFRVQTKNEGG 11810
Score = 158 bits (399), Expect = 6e-38
Identities = 293/1278 (22%), Positives = 490/1278 (38%), Gaps = 155/1278 (12%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW-YKDAAVVEVEKLTRFRQR 360
L VL P++ I + V++ G PPP+ +W + + + E E++T
Sbjct: 23360 LRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 23419
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
L I DTG + +N G + T + P GP+ ID S+
Sbjct: 23420 KVAKLTIRETTIRDTGEYTLELKNVTG-TTSETIKVIILDKPGPPTGPIKIDEIDATSIT 23478
Query: 421 LACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISP---THISDAGTY 473
++ E GAP ++ P + P+ S S+ S T +++ Y
Sbjct: 23479 ISWEPPELDGGAPLSGY-------VVEQRDAHRPGWLPV-SESVTRSTFKFTRLTEGNEY 23530
Query: 474 T--CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
ATN G+ V+ R+ I P +++ + V+ D Y
Sbjct: 23531 VFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETL-------QIFDVSRDGMTLTWYPP 23583
Query: 532 EKDGATLGT---ESHPRIRLD---RNGSLHISQTWSGDIG-----TYTCRVIS----AGG 576
E DG + T +R D R + ++ T G Y RV + G
Sbjct: 23584 EDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 23643
Query: 577 NDSRSAHLRVRQLPHA----PEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSE 631
SR + V P A P++P T +T R +++L W+ P D G S + Y++EM +
Sbjct: 23644 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTT--RTSVSLAWSVPEDEGGSKVTGYLIEMQK 23701
Query: 632 NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS------KDTERVSL 685
+ + K T+ L Y+FR+ A N G G+ + K TE +
Sbjct: 23702 VDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEY 23761
Query: 686 PEEPPTAPPQN---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
P+ Q V G +I I+ +P P I ++ G + +
Sbjct: 23762 PDYELDERYQEGIFVRQGGVIRLTIPIKGKPFP-----------ICKWTKEGQDISKRAM 23810
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEA 802
T L++++ + ++ N G KV + G P P G + +
Sbjct: 23811 IATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKV---RVIGSPNSPEGPLEYDD 23867
Query: 803 TNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSG 860
++R +W P+ + G ++ + E+ E + T + + V V G
Sbjct: 23868 IQVRSVRVSWRPPAD------DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKG 23919
Query: 861 LKKFTEYFTSVLCFTTPG-DGPRSTPQLVRTHEDVPGPVGHLSFSEILD---TSLKVSWQ 916
LK+ EY V G P + + V + P + E+LD +S+ +SW
Sbjct: 23920 LKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 23979
Query: 917 EPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSK 974
P + G +TGY I +E T+ V H +T Y VTGL Y + A
Sbjct: 23980 RPKDDGGSRVTGYYIERKE-TSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDV 24038
Query: 975 GQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYD-GKTSISRWLVEA 1030
G + S ++ + P + P P L I +I SVTLQ+ +P D GK + W+
Sbjct: 24039 GLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYR 24098
Query: 1031 QVGVVGEGEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
Q G W + SN+ + + + L T Y FR+ N G S P + +
Sbjct: 24099 QSG----DSAW----KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 24150
Query: 1089 IQTL----QAP---PDMAPANVSLRTASETSLWLRWMPLPEME-YNGNPESVGYKIKYSR 1140
I+T +AP +M L A++ S + PLP+++ Y E + +
Sbjct: 24151 IKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 24210
Query: 1141 SDGHGKTLSHVVQDRVERDY-----TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRT 1194
SDG TL+ + +++ + T E E T ++ +QA G P + G
Sbjct: 24211 SDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG-- 24268
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKD---SDTQPRFW 1251
+V S+ +V + +M W G K++ ++ +T+
Sbjct: 24269 --AVGSTLRLHVMYIGRPVPAM--TWFH-----------GQKLLQNSENITIENTEHYTH 24313
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFP 1310
LV N R T GKY + V + IL+ + D P P G I+
Sbjct: 24314 LVMKNVQRK---THAGKYKVQLSNVFG---------TVDAILDVEIQDKPDKPTGPIVIE 24361
Query: 1311 EVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
+ S + W+PPA G + + + + A S L +
Sbjct: 24362 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 24421
Query: 1371 YLFRITAQTRKGWGEAAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSD 1427
Y FR++AQ G + E ++V+ ++P P +P + V S +++W+ P SD
Sbjct: 24422 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA--VTKDSCVVAWKPPASD 24479
Query: 1428 GLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEF 1487
G + +R Y ++ RE +W + + + F V L Y+FRVK N G+SE+
Sbjct: 24480 GGAKIRNYYLEKREKKQNKW-ISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24538
Query: 1488 SEESESLTTLQAAPDEAP 1505
SE SE +T P +AP
Sbjct: 24539 SEISEPITPKSDVPIQAP 24556
Score = 154 bits (390), Expect = 7e-37
Identities = 325/1603 (20%), Positives = 591/1603 (36%), Gaps = 176/1603 (10%)
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV-EVEKLTRFRQRNDGGLQISGLVPDDT 375
++ A + +D+P KG P ++ W KD + E ++ + L I +D
Sbjct: 19033 NVKAREQLKIDVPF--KGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDV 19090
Query: 376 GMFQCFARNAAGEVQTS-TYLAVTSIAPNITRGPLDSTVIDGMSVVLA---------CET 425
G ++ N+AG + T + + P GP+ + S+ ++ C+
Sbjct: 19091 GTYELCVSNSAGSITVPITIIVLDRPGPP---GPIRIDEVSCDSITISWNPPEYDGGCQI 19147
Query: 426 SG-----APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
S + TW + +A S+++ R T +GS + A N
Sbjct: 19148 SNYIVEKKETTSTTWHIVSQAVARTSIKIVRLT---TGSEY----------QFRVCAENR 19194
Query: 481 RGVDEASADLVVWARTRITKP--PQDQSVIKGTQASM--------------VCGVTHDPR 524
G S V A + P P V+ T+++M V G + +
Sbjct: 19195 YGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYK 19254
Query: 525 VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH- 583
+W K L ++ ++ G ++ + ++ +I G S+S
Sbjct: 19255 ERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGI--------GKCSKSCEP 19306
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+ R P P T + R++++L W+KP +DG + + YI+E E +
Sbjct: 19307 VPARDPCDPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 19364
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGK-GQFSKDTERVSLPEEPPTAPPQNVIASG 701
+ + T V L + Y+FR+ A N + S+ T + + ++ P V+
Sbjct: 19365 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDD---VEPPRVMMDV 19421
Query: 702 RTNQSIMIQWQPPPESHQNGILKGY---IIRYCLAGLPVGYQFKN-ITDADVNNLL-LED 756
+ I+++ + N + G +I + G+ + + + I D + LL ++D
Sbjct: 19422 KFRDVIVVKAGEVLKI--NADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 19479
Query: 757 LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
I + + N AG S + P P G + + +W P
Sbjct: 19480 CIRRDTGQYVLTLKNVAGT---RSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 19536
Query: 817 PQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTT 876
G + Y ++ E + + Q + V+ L K EY V
Sbjct: 19537 ED--GGADIDYYIV--EKRETSHLAWTICEGELQMTSCK--VTKLLKGNEYIFRVTGVNK 19590
Query: 877 PGDGPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G G ++ + VP P L + + S+ + W P G ++GY I
Sbjct: 19591 YGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERR 19650
Query: 934 EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST--ISSGVPPE 991
E N + P L + TGL Y V A + G S ++ I + P
Sbjct: 19651 EKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVF 19710
Query: 992 LPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 1050
LP PP+ I + G ++T+ + +P +DG I+ + VE + + +W Q
Sbjct: 19711 LPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKS---DDTDWKTSIQSLRG 19767
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS-------RKIQTL-QAPPDMAPAN 1102
+ + L Y FR++ VN VG S PS S R+ + L +M
Sbjct: 19768 TE---YTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTL 19824
Query: 1103 VSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTI 1162
+ AS T M +P + G P + +S+ D +T ++V TI
Sbjct: 19825 IVKAGASFT------MTVP---FRGRPVP---NVLWSKPDTDLRTRAYVDTTDSRTSLTI 19872
Query: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222
E+ + + N + + S T+V + ++ PTN++ T S ++ W +
Sbjct: 19873 ENANRNDSGKYTLTIQNVLSAA--SLTLVVKVLDT--PGPPTNITVQDVTKESAVLSW-D 19927
Query: 1223 VPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR-SAQLTGLGKYVLYEVQVLAFTR 1281
VPE D V Y + EK ++ + V N +R S ++T L + +Y +V
Sbjct: 19928 VPENDGGAPVKNYHI---EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENE 19984
Query: 1282 IGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLN 1341
G G P+ + + + P PP + + SV L W P G + + + L
Sbjct: 19985 FGVGIPAETKEGVK-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALE 20043
Query: 1342 TTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQ 1401
N V+ + + +GL+ S Y FR+ A+ + G + E L+ K ++ +
Sbjct: 20044 KGQKNW--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIK-EQLE 20100
Query: 1402 PPSRPMVQQED----VRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
PP M VRA S L P S P+ T+ +P + ++
Sbjct: 20101 PPEIDMKNFPSHTVYVRAGSNLKVDIPISG--KPLPKVTLSRDGVPLKATMRFNTEITAE 20158
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
+ + + ++ + A N G ++ L + P P ++S T S
Sbjct: 20159 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLD--RPGPPTGPVVISDI--TEES 20214
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLS 1577
V ++W+PP D + + + L A W E+++ + +
Sbjct: 20215 VTLKWEPPKYDGGSQVT----------------NYILLKRETSTAVWTEVSATVARTMMK 20258
Query: 1578 RPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVV-VHGAT 1636
LT E Y+ R+ N G V V T P + V T
Sbjct: 20259 VMKLTTGE--------EYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVT 20310
Query: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAY 1696
+ V W P + + + GY + + + L ++ L + K+ ++ Y
Sbjct: 20311 RESITVGWHEP-VSNGGSAVVGYHLEMKD-RNSILWQKANKLVIRTTHFKVTTISAGLIY 20368
Query: 1697 MVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LE 1755
V A NAAG G S P++ A P +V+ ++++ SV++SW+ P F G +
Sbjct: 20369 EFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKIT 20428
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPE 1811
GY + E DG + + + L + Y FR+ A+ + + E
Sbjct: 20429 GY--IVERRDLPDG--RWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20484
Query: 1812 IEANVTTGPGEGAPG---PPGVPIIVRYSSAIAIHWSSGDPGK 1851
+ +T G P P +V+Y + ++ +G GK
Sbjct: 20485 VVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 20527
Score = 149 bits (376), Expect = 3e-35
Identities = 359/1701 (21%), Positives = 599/1701 (35%), Gaps = 236/1701 (13%)
Query: 305 LEPPQFVKEPERH--ITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTR---FRQ 359
+EPP+ + + + I + +V+ I G P P I+W KD +E+E+ R
Sbjct: 19412 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDG--IEIEERARTEIIST 19469
Query: 360 RNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSV 419
N L + + DTG + +N AG + V P GPL+ +
Sbjct: 19470 DNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLD-KPGPPAGPLEINGLTAEKC 19528
Query: 420 VLAC----ETSGAPRPAITWQKGER-----ILASGSVQLP--RFTPLESGSLLISPTHIS 468
L+ E GA +K E + G +Q+ + T L G+ I
Sbjct: 19529 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI------ 19582
Query: 469 DAGTYTCLATNSRGVDEASADLVVWARTRIT--KPPQDQSVIKGTQASMVCGVTHDPRVT 526
+ N GV E + + A T PP + T+ SM
Sbjct: 19583 ----FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMT---------- 19628
Query: 527 IRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W + + G+E I ++R + Y RV S G + RV
Sbjct: 19629 --LCWSRPESDGGSEISGYI-IERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRV 19685
Query: 587 RQ-----------------------LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPL 622
LP P P S + I + W KP FDG +P+
Sbjct: 19686 YAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDS--GKTTITIAWVKPLFDGGAPI 19743
Query: 623 IRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTE 681
Y +E + ++ W + S+ + T T+ GL Y FR+ +VN VG S ++
Sbjct: 19744 TGYTVEYKKSDDTDWKTSIQSL--RGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19801
Query: 682 RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILK---GYIIRYCLAGLPVG 738
PQ IA R + + + E + I+K + + G PV
Sbjct: 19802 ------------PQ--IAKEREEEPL---FDIDSEMRKTLIVKAGASFTMTVPFRGRPVP 19844
Query: 739 YQFKNITDADVNNLLLEDLI-IWTNYEIEVAAYNSAG------LGVYSSKVTEWTLQGVP 791
+ D D+ D T+ IE A N +G V S+ ++ +
Sbjct: 19845 NVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLD 19904
Query: 792 TV-PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 850
T PP N+ + + +W+ P N K E + + V+ N
Sbjct: 19905 TPGPPTNITVQDVTKESAVLSWDVPE----NDGGAPVKNYHIEKREASKKAWVSVTNNCN 19960
Query: 851 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDT 909
+ V+ L++ Y+ V G G P T + V+ E P P L + I
Sbjct: 19961 RLSYK--VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK-PSPPEKLGVTSISKD 20017
Query: 910 SLKVSWQEPGEKNGI-LTGYRISWEEYNRTN------TRVTHYLPNVTLEYRVTGLTALT 962
S+ ++W +P G + Y + E + N + TH++ V+GL +
Sbjct: 20018 SVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHV--------VSGLRENS 20069
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
Y V A G + + +L P + + N S T+ R G + K
Sbjct: 20070 EYFFRVFAENQAGLSDPRELLLPVLIKEQL--EPPEIDMKNF--PSHTVYVRAGSNLKVD 20125
Query: 1023 IS-RWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +V + +G + + E A ++ + T + R ++ +S
Sbjct: 20126 IPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY-EITAANSSG 20184
Query: 1082 PSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY-KIKYS 1139
++ I L P P P +S +E S+ L+W P +Y+G + Y +K
Sbjct: 20185 TTKAFINIVVLDRPGPPTGPVVIS--DITEESVTLKWEP---PKYDGGSQVTNYILLKRE 20239
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
S +S V + + + L EY+ +++A N G + +
Sbjct: 20240 TSTAVWTEVSATVARTMMK---VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYT 20296
Query: 1200 SSGPTNVSALA-TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN-- 1256
+ GP + + T S+ V W E P ++ V+GY + K+++S W
Sbjct: 20297 TPGPPSTPWVTNVTRESITVGWHE-PVSNGGSAVVGYHLEMKDRNS----ILWQKANKLV 20351
Query: 1257 -SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVR 1313
+ ++T + ++YE +V A G G PSHP P+L D PP + ++
Sbjct: 20352 IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVL---AIDACEPPRNVRITDIS 20408
Query: 1314 TTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
SV L WQ PA G + I R + + Q+ +GL S Y F
Sbjct: 20409 KNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEF 20468
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPP--SRPMVQQEDVRARS-VLLSWEPGSDGL- 1429
R+ A+ G +V D P P+ E V+ R+ + G G
Sbjct: 20469 RVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKP 20528
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+P + +EL + AL + + +S ++ S + +K N +G + +
Sbjct: 20529 APTIEWYKDDKELQTN--ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 20586
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGL 1549
+ L + P P + T + + W+PPA+D G +I +
Sbjct: 20587 RVQILD--KPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITH-------- 20628
Query: 1550 RGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP 1609
+ + W+ ++ +L +T + K Y R+ N G G
Sbjct: 20629 --YIVEKRETSRVVWSMVS-----EHLEECIIT---TTKIIKGNEYIFRVRAVNKYGIGE 20678
Query: 1610 SSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR 1668
V A T P + V T + V W P D DI G YF E +
Sbjct: 20679 PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADG-GSDISG---YFLEKRD 20734
Query: 1669 GNLTERVKTL--FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ---GQTQQAA 1723
K L + + K+ LT + Y V A NAAG GP S P++
Sbjct: 20735 KKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 20794
Query: 1724 PSAPSSVKFSELTTTSVNVSWEAPQFPNG-ILEGYRLVYEPCSPVDGVSKIVTVDVKGN- 1781
P P+ ++ ++ T +S+ + W P + G + GY + + TV KG
Sbjct: 20795 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE----EEWTTVSTKGEV 20850
Query: 1782 SPLWLKVKDLAEGVTYRFR------------------IRAKTFTYGPEIEANVTTGPGEG 1823
V +L GV Y FR ++AK PEI+ +V
Sbjct: 20851 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVI 20910
Query: 1824 APGPPGVPIIVRYSS--AIAIHWSSGDPGKGPITRYVIEARPS------------DEGLW 1869
A V +++ + + W + G RY IE S D G +
Sbjct: 20911 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20970
Query: 1870 DILIKDIPKEVSSYTFSMDIL 1890
+ I++ E S T S+ +L
Sbjct: 20971 ILTIENGVGEPKSSTVSVKVL 20991
Score = 149 bits (376), Expect = 3e-35
Identities = 360/1644 (21%), Positives = 594/1644 (36%), Gaps = 223/1644 (13%)
Query: 367 ISGLVPDDTGMFQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMS 418
++ L + +F+ A+N G E T+ + + P I + I G
Sbjct: 23324 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23383
Query: 419 VVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
V L +G P PA +W G ++ S V + T + L I T I D G YT
Sbjct: 23384 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV--AKLTIRETTIRDTGEYTLEL 23441
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASM------------VCGVTHDPRV 525
N G + +++ + P I T ++ + G + R
Sbjct: 23442 KNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRD 23501
Query: 526 TIRYIW--EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
R W + T T R+ ++ T IG+Y + + + RS+
Sbjct: 23502 AHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSI 23557
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
++P PE + V R + LTW P D G S + YI+E E A V +
Sbjct: 23558 ----RIPGPPE--TLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNK 23611
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER-VSLPEEPPTAPPQNVIASG 701
V T GL Y+ R+ A+N G G+ S+ ++ V++ P PQN +
Sbjct: 23612 VPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTD 23671
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T S+ + W P E + GY+I + N T + L L
Sbjct: 23672 TTRTSVSLAWSVP-EDEGGSKVTGYLIEMQKVDQHEWTKC-NTTPTKIREYTLTHLPQGA 23729
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
Y V A N+ G G P PG V + + + ++
Sbjct: 23730 EYRFRVLACNAGG-------------PGEPAEVPGTVKV----TEMLEYPDYELDERYQE 23772
Query: 822 GI--NQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
GI QG + P + + + QD ++ + TE V+ GD
Sbjct: 23773 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL---VIKEADRGD 23829
Query: 880 ------------GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
G ++ VR P G L + +I S++VSW+ P + G +
Sbjct: 23830 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23889
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV--SASTI 984
GY + E + T V GL Y V+A G + S +
Sbjct: 23890 GYILERREVPKAAWYTIDSRVRGT-SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 23948
Query: 985 SSGVPPELPGPPTNLG-ISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWL 1042
+ P P PP+N + ++ SV+L + RP DG + ++ + +E + ++W
Sbjct: 23949 TPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETST---DKW- 24004
Query: 1043 LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG---TSPPSQPSRKIQTLQAPPDMA 1099
+ + V L P Y FR+ N VG TSP S+P P
Sbjct: 24005 -VRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQ-- 24061
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ER 1158
P + + + S+ S+ L+W + E +G E +GY ++Y +S S+ ++R+ ++
Sbjct: 24062 PGELEILSISKDSVTLQW---EKPECDGGKEILGYWVEYRQSGDSAWKKSN--KERIKDK 24116
Query: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP----------TNVSA 1208
+TI L E TEY +V A N G +T + + P T +
Sbjct: 24117 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGE 24176
Query: 1209 LATTSSSMLVRWSEVPEADRNGLVLGYKVMYK-EKDSDTQPRFWLVEGNSSRSAQLTGLG 1267
A S ++ R + R G L YK D T + E G
Sbjct: 24177 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDE-------G 24229
Query: 1268 KYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL----IWQP 1323
Y +A +G+ S +L+ T PG P+ + +++RL I +P
Sbjct: 24230 VYTC-----IATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRP 24284
Query: 1324 PAAPNGIILAYQITHRLNTTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A + + N T NT ++ + ++ T G +++ G
Sbjct: 24285 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK-------YKVQLSNVFG 24337
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYTIQTRE 1441
+A ++ E +D+P P+ P+V E + S ++SW+P DG S + Y ++ E
Sbjct: 24338 TVDA----ILDVEIQDKPDKPTGPIVI-EALLKNSAVISWKPPADDGGSWITNYVVEKCE 24392
Query: 1442 LPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
G W L S+++S + L Y FRV A N G S+ E S + +
Sbjct: 24393 AKEGAEWQLVSSAISVTTCRIV--NLTENAGYYFRVSAQNTFGISDPLEVSS--VVIIKS 24448
Query: 1501 PDE---APTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
P E AP ++T T S ++ W+PPA D G +IR + L
Sbjct: 24449 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDG------GAKIR----------NYYLEKR 24492
Query: 1558 NNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617
W +T+ T + + NL + YE R+ N GE S E
Sbjct: 24493 EKKQNKWISVTTEEIRE-------TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPI 24545
Query: 1618 VGEA-VPTAAPR--------NVVVHGATATQLDVTWEPPPL------------DSQNGDI 1656
++ VP AP NV VT P P+ D I
Sbjct: 24546 TPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRI 24605
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ 1716
Q +K + + ++T+ T++ + + +++G + V V A P++
Sbjct: 24606 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL---PKTLEGM 24662
Query: 1717 GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTV 1776
G A S+K ++W+ Q Y+++ V++ T
Sbjct: 24663 GAVH-ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI---------VTRSFTS 24712
Query: 1777 DVKGNSPLWLKVKDLAEGVTY---RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPII 1833
V N ++ KD V RF I KT +E +V P P GV +
Sbjct: 24713 LVFPNG---VERKDAGFYVVCAKNRFGIDQKT------VELDVADVPDP----PRGVKVS 24759
Query: 1834 VRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892
++ + W+ G IT Y++E + W + + +++ L
Sbjct: 24760 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-----GQARETRYTVINLFG 24814
Query: 1893 GVSYDFRVIAVNDYGFGTPSSPSQ 1916
SY FRVIA N +G PS PS+
Sbjct: 24815 KTSYQFRVIAENKFGLSKPSEPSE 24838
Score = 147 bits (372), Expect = 8e-35
Identities = 327/1497 (21%), Positives = 538/1497 (35%), Gaps = 177/1497 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
ND G+ ++PD + R A + + L T + V G+S+
Sbjct: 14380 NDAGVGEPAVIPD----VEIVEREMAPDFELDAELRRTLV------------VRAGLSIR 14423
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT-HISDAGTYTCLATN 479
+ G P P +TW K L + + ES +LLI P + D G + N
Sbjct: 14424 IFVPIKGRPAPEVTWTKDNINLKNRA----NIENTESFTLLIIPECNRYDTGKFVMTIEN 14479
Query: 480 SRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH--------DPRVTIRYIW 531
G + R+ P ++ T + H R+T YI
Sbjct: 14480 PAGKKSG------FVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT-NYIV 14532
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA-----GGNDSRSAHLRV 586
EK AT + S + + T + Y RV++ G + ++
Sbjct: 14533 EKREATRKSYSTATTKCHK---CTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14589
Query: 587 RQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDP 645
+ P P+ + + + ++L W KP DG S + Y++E + + +V
Sbjct: 14590 SEAPSPPDS--LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV-- 14645
Query: 646 KATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT-----ERVSLPEEPPTAPPQN-VIA 699
K V+ L Y F++ AVN G+ + E+ LPE Q VIA
Sbjct: 14646 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIA 14705
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
N + I P+ I++ V ++ T A L + + +
Sbjct: 14706 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQR---VNFE----TTATSTILNINECVR 14758
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
+ + A N G V + +P P G + + +S + F+W+ P
Sbjct: 14759 SDSGPYPLTARNIVG---EVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPEND- 14814
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
G+ ++ E Q + T V + + + L EY V G
Sbjct: 14815 -GGVPISNYVV--EMRQTDSTTWVELATTVIRTTYKA--TRLTTGLEYQFRVKAQNRYGV 14869
Query: 880 GPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYN 936
GP T + + VPGP G + + S+ +SW EP G + GY + +E N
Sbjct: 14870 GPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERN 14929
Query: 937 RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA--MTSKGQGQVSASTISSGVPPELPG 994
+ ++ +GLT Y V A M K + + + + P + PG
Sbjct: 14930 GILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPG 14989
Query: 995 PPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDA 1053
P L NI +VTL++ +P Y G I+ ++VE + G + + L NE
Sbjct: 14990 KPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENE--- 15043
Query: 1054 RSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQPSRKI---QTLQAPP---DMAPANVSLR 1106
V L Y FR+ N G SPPS+PS I ++AP D+ + +
Sbjct: 15044 --FTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 15101
Query: 1107 TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIE 1163
A E + P P ME++ + + + K ++ + V +D T
Sbjct: 15102 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIK------IADFSTNLVNKDSTRR 15155
Query: 1164 DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEV 1223
D +T + A N G V R P GP V+ + TS ++ W
Sbjct: 15156 DSGAYT-----LTATNPGGFAKHIFNVKVLDRPG-PPEGPLAVTEV--TSEKCVLSW--F 15205
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL--TGLGKYVLYEVQVLAFTR 1281
P D G + + ++ K +T W + + +L T L K Y +V+A +
Sbjct: 15206 PPLDDGGAKIDHYIVQKR---ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNK 15262
Query: 1282 IGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRL 1340
G G P P+L P PP + S+ + W P + G + I R
Sbjct: 15263 YGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR 15322
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG--EAAEALVVTTEKRD 1398
+ + +Y +GL Y FRI A+ G +
Sbjct: 15323 DKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 15382
Query: 1399 RPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
+P PP P V D S+ ++W +P DG S + Y ++ W + +
Sbjct: 15383 KPGPPGNPRVL--DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLK 15440
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
A+S+ + L YK R+ A N G E P ++ TP
Sbjct: 15441 ATSYTITGLTENQEYKIRIYAMNSEGLGE------------------PALVPGTPKAEDR 15482
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT-LRGINNPGATWAELTSMYSMRNL 1576
+L P E +++ L + R LR F ++G P WA S+
Sbjct: 15483 ML-----PPEIELDADLRKV-VTIRACC--TLRLFVPIKGRPAPEVKWAR-DHGESLDKA 15533
Query: 1577 SRPSLTQYEL---DNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVV 1631
S S + Y L N+N+ + ++V N SS + FV V P+++
Sbjct: 15534 SIESTSSYTLLIVGNVNRFDSGKYILTVEN------SSGSKSAFVNVRVLDTPGPPQDLK 15587
Query: 1632 VHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA---ENSVKLK 1688
V T T + +TW+PP LD G KI + ++ T + + + S K+
Sbjct: 15588 VKEVTKTSVTLTWDPPLLDG------GSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVD 15641
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
L +Y V A N G G + + P P + ++T SV++SWE P+
Sbjct: 15642 QLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPE 15701
Query: 1749 FPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
G + GY +V D + TV V + + L +G Y FR+ A+
Sbjct: 15702 HDGGSRILGY-IVEMQTKGSDKWATCATVKVTEAT-----ITGLIQGEEYSFRVSAQ 15752
Score = 142 bits (357), Expect = 5e-33
Identities = 357/1681 (21%), Positives = 598/1681 (35%), Gaps = 218/1681 (12%)
Query: 289 RSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAV 348
RS +VP V + V+EP VK + ++ + + I G P P+ITW KD
Sbjct: 16843 RSLAVPIVAKDL---VIEPD--VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG-- 16895
Query: 349 VEVEKLTRFRQRND---GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ +++ TR + L I DD G + N G+ +T++ VT P+
Sbjct: 16896 LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-KTASIEIVTLDKPDPP 16954
Query: 406 RGPLDSTVIDGMSVVLACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+GP+ + S+ L+ T G QK + V + +L
Sbjct: 16955 KGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVV---SATVARTTLK 17011
Query: 462 ISPTHISDAGTYTCLATNSRGVDEA--SADLVVWARTRITKPP---------QDQSVIK- 509
++ + A N G A S +V + PP +D VI+
Sbjct: 17012 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 17071
Query: 510 ----GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIG 565
S V G + + +W K T+ ++ + + ++ + +
Sbjct: 17072 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQ-------NLEEGIEYEFR 17124
Query: 566 TYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIR 624
Y ++ G S R P P + V+R I L WTKP +DG S +
Sbjct: 17125 VYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITG 17182
Query: 625 YILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT---- 680
YI+E + + + + T TV GL + Y+FR+ A N G D+
Sbjct: 17183 YIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 17242
Query: 681 ---ERVSLP--EEPPTAPPQNVIASGRT-NQSIMIQWQPPPESHQNGILKGYIIRYCLAG 734
+ V LP P V+ +G T + +P P +
Sbjct: 17243 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP---------------TIEW 17287
Query: 735 LPVGYQFKNITDADVNN------LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ 788
L + + ++ N L+++D I + + A N AG + V +
Sbjct: 17288 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV---KVL 17344
Query: 789 GVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN 848
P P G V S TW SP +G + + + E V A
Sbjct: 17345 DRPGPPEGPVQVTGVTSEKCSLTW---SPPLQDGGSDISHYVVEKRETSRLAWTVVASEV 17401
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEI 906
+S+ V+ L + EY ++ G G S P L++ +PGP L + I
Sbjct: 17402 VTNSLK---VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNI 17458
Query: 907 LDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVT-LEYRVTGLTALTT 963
S+ V W P G + GY + E+ +R+ R + +T L RVTGLT
Sbjct: 17459 AKDSMTVCWNRPDSDGGSEIIGYIV--EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 17516
Query: 964 YTIEVAAMTSKGQGQVSASTI--SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGK 1020
Y V+A + G G+ S +T+ + P PGPPTN I + S+TL + +P YDG
Sbjct: 17517 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 17576
Query: 1021 TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG-- 1078
+ I ++VE + EEW ++ + R E+ L Y R+ +N VG
Sbjct: 17577 SEILGYVVEI---CKADEEEWQIVTPQTGLRVTR-FEISKLTEHQEYKIRVCALNKVGLG 17632
Query: 1079 --TSPPS--QPSRKIQTLQAPPDM-APANVSLRTASETSLWLRWMPLPEMEYNGNPESVG 1133
TS P +P K++ + D + +R + + + G P
Sbjct: 17633 EATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARI--------HIPFKGRPTP-- 17682
Query: 1134 YKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
+I +SR +G + + +I++ + + ++ N+ GS TV
Sbjct: 17683 -EITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTV--- 17738
Query: 1194 TRESVPSSG-PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL 1252
+ + + G P N++ S + W E P D V Y + +K T+ +
Sbjct: 17739 --KVLDTPGPPQNLAVKEVRKDSAFLVW-EPPIIDGGAKVKNYVI---DKRESTRKAYAN 17792
Query: 1253 VEGNSSR-SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPE 1311
V S+ S ++ L + +Y +V+A G G P + + P PP + +
Sbjct: 17793 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-PSPPGKVTLTD 17851
Query: 1312 VRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
V TS L+W+ P G +L Y + + T + E +A TGL
Sbjct: 17852 VSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNA---VVTGLSSGQE 17908
Query: 1371 YLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL----------- 1419
Y FR+ A KG + V K QP + ++A L
Sbjct: 17909 YQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPR 17968
Query: 1420 --LSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVK 1477
+SW DG P++ T E + LH N F K+ V
Sbjct: 17969 PNISWV--KDG-EPLKQTTRVNVEETATSTVLHIK--EGNKDDF----------GKYTVT 18013
Query: 1478 ATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGF 1537
ATN G + +E + + P P + V+I W+PPA
Sbjct: 18014 ATNSAGTA--TENLSVIVLEKPGPPVGPVRFDEV--SADFVVISWEPPA----------- 18058
Query: 1538 RIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRR 1594
Y G + + + + TW +++ + T ++ L
Sbjct: 18059 --------YTGGCQISNYIVEKRDTTTTTWHMVSATVAR--------TTIKITKLKTGTE 18102
Query: 1595 YEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQN 1653
Y+ R+ N G+ + V V P V + Q+ V W P D
Sbjct: 18103 YQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG-G 18161
Query: 1654 GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST 1713
I GY + E + L ++ + + K L Y V+A N G G S
Sbjct: 18162 TKIIGYHLEQKE-KNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18220
Query: 1714 PTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSK 1772
++ + P + +T +V + W+ P + G + GY + E DG +
Sbjct: 18221 VSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGY--IVEKKDLPDG--R 18276
Query: 1773 IVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPEIEANVTTGPGEGAPGPP 1828
+ V L E Y FR+ A+ F+ + +T AP
Sbjct: 18277 WMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNAS 18336
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
P +Y I +H +G+ +V+EA + + D++ KE+ M+
Sbjct: 18337 LDP---KYKDVIVVH--AGE-------TFVLEADIRGKPIPDVVWSKDGKELEETAARME 18384
Query: 1889 I 1889
I
Sbjct: 18385 I 18385
Score = 139 bits (350), Expect = 3e-32
Identities = 336/1554 (21%), Positives = 565/1554 (36%), Gaps = 218/1554 (14%)
Query: 378 FQCFARNAAGEVQ---TSTYLAVTSIAPN----ITRGPLDSTVID-GMSVVLACETSGAP 429
F+ A N AGE + T+ + T I I G D V G + + G P
Sbjct: 9407 FRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRP 9466
Query: 430 RPAITWQ---KGERILASGSVQLPRFTPLE----SGSLLISPTHISDAGTYTCLATNSRG 482
P +W+ K ++ + G +P LE S ++I S G Y+ A N G
Sbjct: 9467 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 9526
Query: 483 VDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVT-----HDPRVTIR-YIWEKDGA 536
A+ + V + PP+D V T+ S C ++ D I+ Y+ EK
Sbjct: 9527 QKTANCRVKVMD---VPGPPKDLKVSDITRGS--CRLSWKMPDDDGGDRIKGYVIEK--R 9579
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRV-----ISAGGNDSRSAHLRVRQLPH 591
T+ ++ ++ D + + + Y RV G R +
Sbjct: 9580 TIDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIY 9638
Query: 592 APEHPVAT-LSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLA-----SVD 644
P+ P+ + + + ++L+W P DG SP+ YI+E + T A D
Sbjct: 9639 PPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9698
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSK-----DTERVSLPE--------EPPT 691
+ TV+ LV Y+FR+ AVN G + S D +R +P E
Sbjct: 9699 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9758
Query: 692 APPQNVIASGRTNQSIMIQW-QPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
N++A + + W + PP+ N PV Y D VN
Sbjct: 9759 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-------------PVLY------DTHVN 9799
Query: 751 NLLLED---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ--GVPTVPPGNVHAEATNS 805
L+++D L+I + + Y + + E L G P P G + E+ ++
Sbjct: 9800 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSA 9859
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
+ +W P + G K+ + E+ E + + + L +
Sbjct: 9860 DQMTLSWFPPKD------DGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGH 9913
Query: 866 EYFTSVLCFTTPGDGPR--STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG 923
EY ++ G G S P+ R VPG + S + S+ V+W+EP G
Sbjct: 9914 EYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGG 9973
Query: 924 I-LTGYRIS--------WEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
+TGY + W+ NR + + + Y+VTGL + Y V A+ +
Sbjct: 9974 SPVTGYWLEMKDTTSKRWKRVNRDPIKAM----TLGVSYKVTGLIEGSDYQFRVYAINAA 10029
Query: 975 GQGQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQ 1031
G G S + ++ P PGPP +++ S L++ P DG + ++ ++VE +
Sbjct: 10030 GVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK 10088
Query: 1032 VGVVGEG-EEWLLIHQLSNEPDAR--SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
EG EEW + + + R + V L Y FR+R VNI G P + +
Sbjct: 10089 ----EEGKEEW----EKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV 10140
Query: 1089 IQ---TLQAPPDMAPANVSLRTASETS------LWLRWMPLPEMEYNGNPESVGYKIKYS 1139
I+ L +P A+V R ++ P P + +N N ++ +
Sbjct: 10141 IEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE---- 10196
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
+ + + I++ + + + A N +G +T++ + VP
Sbjct: 10197 ---------ATIETTAISSSMVIKNCQRSHQGVYSLLAKNE--AGERKKTIIVDVLD-VP 10244
Query: 1200 SSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW--LVEGNS 1257
T A T+ S + W PE D + Y + +E D R W + +
Sbjct: 10245 GPVGTPFLAHNLTNESCKLTWFS-PEDDGGSPITNYVIEKRESDR----RAWTPVTYTVT 10299
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTT 1315
++A + GL + Y ++ A IG G + ++ R VP P + EV
Sbjct: 10300 RQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKN 10359
Query: 1316 SVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
+V L W PP G I+ Y + RL T + T + L +R+YT GLK Y +
Sbjct: 10360 TVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLL--SRKYTVKGLKEGDTYEY 10417
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
R++A G G+ + T K D PP+ + D R + L+ G R
Sbjct: 10418 RVSAVNIVGQGKPSFCTKPITCK-DELAPPTLHL----DFRDK---LTIRVGEAFALTGR 10469
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND------IGDSEF 1487
Y + P W A V + + I K + K ++ + +S
Sbjct: 10470 Y---SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10526
Query: 1488 SEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYE 1547
S + + P +S T ++I W+PP +D + + I +E+ +
Sbjct: 10527 SRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG-GSKITNYIIEKKEVGKD 10585
Query: 1548 GLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGE 1607
W +T S + T ++ L + + Y R+ N G
Sbjct: 10586 ---------------VWMPVT--------SASAKTTCKVSKLLEGKDYIFRIHAENLYGI 10622
Query: 1608 GPSSPPQEVFVGE--AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
+ + VP AP +V T VTW P I Y + E
Sbjct: 10623 SDPLVSDSMKAKDRFRVPD-APDQPIVTEVTKDSALVTWNKP--HDGGKPITNYILEKRE 10679
Query: 1666 AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQA 1722
K ++ +L Y V+A N G G P S P + A
Sbjct: 10680 TMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIA 10739
Query: 1723 APSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGN 1781
PS P + + + T SV+++W+ P+ G + GY + Y+ D + +
Sbjct: 10740 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVG--DEEWRRANHTPESC 10797
Query: 1782 SPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
KV L +G TY+FR+ A GE P P++V+
Sbjct: 10798 PETKYKVTGLRDGQTYKFRVLA-------------VNAAGESDPAHVPEPVLVK 10838
Score = 138 bits (347), Expect = 7e-32
Identities = 278/1273 (21%), Positives = 477/1273 (37%), Gaps = 148/1273 (11%)
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNN 751
PPQ++ T S+ + W PP + I K YI+ + + + T+ +
Sbjct: 15582 PPQDLKVKEVTKTSVTLTWDPPLLDGGSKI-KNYIVEKRESTRKA---YSTVATNCHKTS 15637
Query: 752 LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
++ L +Y V A N G+G+ ++ E +PPG + ++ +
Sbjct: 15638 WKVDQLQEGCSYYFRVLAENEYGIGL-PAETAESVKASERPLPPGKITLMDVTRNSVSLS 15696
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSV 871
W P + I GY + ++ T T + + ++GL + EY V
Sbjct: 15697 WEKPEHDGGSRI-LGYIVEMQTKGSDKWATCATVK------VTEATITGLIQGEEYSFRV 15749
Query: 872 LCFTTPG-DGPRSTPQLVRTHEDVPGPVGHL---SFSEILDTSLKVSWQEPGEKNGILTG 927
G PR V + V P L +F+ + LKV G +T
Sbjct: 15750 SAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTW 15809
Query: 928 YR--ISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
++ + ++ R N T N L + + Y +++ S G+ + + I
Sbjct: 15810 HKDNVPLKQTTRVNAESTEN--NSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIV 15865
Query: 986 SGVPPELPGPPTN-LGISNIGPRSVTLQFRPG-YDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ PGPPT + + + S+TL + P YDG +SI+ ++VE + +
Sbjct: 15866 L----DKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR-------DTSTT 15914
Query: 1044 IHQLSNEPDARS-MEVPDLNPFTCYSFRMRQVNIVGTSP--PSQPSRKIQTLQAPPDMAP 1100
Q+ + AR+ ++ L Y FR+ N G S S+P+ + P
Sbjct: 15915 TWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGT 15974
Query: 1101 ANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV---E 1157
V+L +S S+ ++W E +G +GY ++ + ++ V ++ +
Sbjct: 15975 PVVTL--SSRDSMEVQWN---EPISDGGSRVIGYHLERKERN----SILWVKLNKTPIPQ 16025
Query: 1158 RDYTIEDLEEWTEYRVQVQAFNAIGSGP---WSQTVVGRTRESVPSSGPTNVSALATTSS 1214
+ LEE EY +V A N +G G S+ V R P P A+ T +
Sbjct: 16026 TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD----PCDPPGRPEAIIVTRN 16081
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA---------QLTG 1265
S+ ++W + P D + GY V KE L EG +++ ++TG
Sbjct: 16082 SVTLQWKK-PTYDGGSKITGYIVEKKE----------LPEGRWMKASFTNIIDTHFEVTG 16130
Query: 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI---WQ 1322
L + YE +V+A G S T D PP + P+ + T V ++
Sbjct: 16131 LVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFK 16190
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A G + + + +NTA +E+ + AT L + K
Sbjct: 16191 VDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF----ATSLSVKDAVRVDSGNYILKA 16246
Query: 1383 WGEAAE-ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSPVRYYTIQTR 1440
A E ++ V + DRP PP P+V V A L+W+P DG S + Y ++ R
Sbjct: 16247 KNVAGERSVTVNVKVLDRPGPPEGPVVIS-GVTAEKCTLAWKPPLQDGGSDIINYIVERR 16305
Query: 1441 ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
E W + A+V S V +L Y FR+ A N G E E +
Sbjct: 16306 ETSRLVWTVVDANVQ--TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFV 16363
Query: 1501 PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 1560
+AP VT T S+++ W+ PA D + IL G+ L +
Sbjct: 16364 VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL----------------GYVLEKRDKE 16407
Query: 1561 GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ--EVFV 1618
G W R + L + L ++ YE R+S NA G SPP +
Sbjct: 16408 GIRWTRC----HKRLIGELRL---RVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKAC 16460
Query: 1619 GEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
P N V T + + ++W P D +IQGY + + G T
Sbjct: 16461 DPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG-GCEIQGYIVEKCDVSVGEWTMCTPPT 16519
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ + +++++ L Y + A N AG G + A P V+ +L
Sbjct: 16520 GINKTNIEVEKLLEKHEYNFRICAINKAGVG----------EHADVPGPIIVE-EKLEAP 16568
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPC----------SPVDG-VSKIVTVDVKGN-SPLWL 1786
+++ E + N G ++ P VDG + +DV + + L L
Sbjct: 16569 DIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 16628
Query: 1787 KVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSS 1846
+ + Y + + T + V P P + + +++I W
Sbjct: 16629 DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSP----PVNLKVTEITKDSVSITWEP 16684
Query: 1847 G-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
G I Y++E R + + ++ + K ++ +D L+ G SY FRV A N+
Sbjct: 16685 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKN----SWKIDQLQEGCSYYFRVTAENE 16740
Query: 1906 YGFGTPSSPSQSV 1918
YG G P+ + +
Sbjct: 16741 YGIGLPAQTADPI 16753
Score = 130 bits (326), Expect = 2e-29
Identities = 330/1569 (21%), Positives = 558/1569 (35%), Gaps = 197/1569 (12%)
Query: 222 KNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV-LLSGGISDHNRR---LTIPNPTGS 277
K ++ AG S + V+ P + I W K G+ L S I D L +
Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPV---ITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 23138
Query: 278 DAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV-DIPCQAKGVP 336
DAG Y EA +S + V P VK E ++ + + +IP G P
Sbjct: 23139 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE--VSRDSVTITWEIPTIDGGAP 23196
Query: 337 PPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLA 396
+ K A + K T + + +ISGLV F+ N G +
Sbjct: 23197 VNNYIVEKREAAMRAFK-TVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE--- 23252
Query: 397 VTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA-------SGSVQL 449
TS A ++ PL ++ + V + T +P + G R+ +G+ +
Sbjct: 23253 -TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPL--YDGGSRLTGYVLEACKAGTERW 23309
Query: 450 PRFTPLESGSLLISPTHISDAGTYT--CLATNSRGVDEASA--------DLVVWARTRIT 499
+ L+ L + T +++ Y A N +GV E DL V ++
Sbjct: 23310 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23369
Query: 500 KPPQDQ-SVIKGTQASMVCGVTHDPRVTIRYIWE----KDGATLGTESHPRIRLDRNGSL 554
PQ V G +V + P + + ++ + E+H ++ L
Sbjct: 23370 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV-----AKL 23424
Query: 555 HISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTK 614
I +T D G YT + + G S + + + P P P+ + ++ +I ++W
Sbjct: 23425 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIK-IDEIDATSITISWEP 23483
Query: 615 P-FDGNSPLIRYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVG 672
P DG +PL Y++E + + P W + SV T L Y FR+ A N G
Sbjct: 23484 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFG 23541
Query: 673 KGQFSKDT-----ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYI 727
G + + + +P P T +V G T + W PP E + GYI
Sbjct: 23542 IGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMT-----LTWYPP-EDDGGSQVTGYI 23595
Query: 728 IRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTL 787
+ + + + L YE V A N+ G G S+ ++ +
Sbjct: 23596 VERKEVRADRWVRVNKVP-VTMTRYRSTGLTEGLEYEHRVTAINARGSGK-PSRPSKPIV 23653
Query: 788 QGVPTVPPG---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT 844
P PPG N T T++ W+ P + + + GY LI + + E T
Sbjct: 23654 AMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVT-GY-LIEMQKVDQHEWTKCN 23711
Query: 845 ARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFS 904
P I ++ L + EY VL G G + +VPG V
Sbjct: 23712 TTPT---KIREYTLTHLPQGAEYRFRVLACNAGGPGEPA---------EVPGTVKVTEML 23759
Query: 905 EILDTSLKVSWQE----------------PGEKNGILTGYRISWEEYNRTNTRVTHYLPN 948
E D L +QE G+ I + + R +
Sbjct: 23760 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE 23819
Query: 949 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRS 1008
+ ++ G + TY + + K + I S PE P L +I RS
Sbjct: 23820 LVIKEADRGDSG--TYDLVLENKCGKKAVYIKVRVIGSPNSPEGP-----LEYDDIQVRS 23872
Query: 1009 VTLQFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
V + +RP DG I +++E + W + + + S+ V L Y
Sbjct: 23873 VRVSWRPPADDGGADILGYILERREVPKAA---W---YTIDSRVRGTSLVVKGLKENVEY 23926
Query: 1068 SFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY 1125
FR+ N G S P + + +T PP+ + +++S+ L W +
Sbjct: 23927 HFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD--- 23983
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
+G GY I+ + K + H YT+ L EY+ ++ A N +G
Sbjct: 23984 DGGSRVTGYYIE-RKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSE 24042
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
+ P S+ VV + PS P + L+ + S+ ++W E PE D +LGY V Y++
Sbjct: 24043 TSPASEPVVCKDPFDKPSQ-PGELEILSISKDSVTLQW-EKPECDGGKEILGYWVEYRQS 24100
Query: 1243 DSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT-LDDVP 1301
D+ + E + + GL + YE +V A G P + +T L
Sbjct: 24101 -GDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGE 24159
Query: 1302 GPPMGILFPEVRTT---SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P + +V T + +L Q P I Y+ L + ++ R
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-----MSSDGR 24214
Query: 1359 QYTATGL--KPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416
+T T + + E ++ A G E + L++ + P P +
Sbjct: 24215 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYY------- 24267
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY---- 1472
G+ G + + R +P+ W H + N+ + ++ + +T
Sbjct: 24268 --------GAVGSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKN 24318
Query: 1473 --------KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
K++V+ +N G + + E +Q PD+ + + S +I W+P
Sbjct: 24319 VQRKTHAGKYKVQLSNVFGTVDAILDVE----IQDKPDKPTGPIVIEALLKNSAVISWKP 24374
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
PA+D + + + E GA W ++S S+T
Sbjct: 24375 PADDG-GSWITNYVVEKCEA--------------KEGAEWQLVSSAI--------SVTTC 24411
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT-----AAPRNVVVHGATATQ 1639
+ NL ++ Y R+S N G S P EV + + AP + T
Sbjct: 24412 RIVNLTENAGYYFRVSAQNTFG---ISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24468
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
V W+PP D I+ Y + E ++ N V T + E +KNL Y
Sbjct: 24469 CVVAWKPPASDG-GAKIRNYYLEKRE-KKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 24526
Query: 1700 VAAFNAAGD 1708
V N G+
Sbjct: 24527 VKCENLGGE 24535
Score = 128 bits (321), Expect = 7e-29
Identities = 170/673 (25%), Positives = 261/673 (38%), Gaps = 90/673 (13%)
Query: 1299 DVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
DVPGP + E V L W+ P G + + R + A S
Sbjct: 6716 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 6774
Query: 1359 QYTATGLKPESV-YLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
++T TGL+ V YLFR++A+ R G GE E V K D P PP + DV
Sbjct: 6775 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT--DVNR 6832
Query: 1416 RSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
V L+WEP DG + + Y I+ R+ S RW + + S+ + D ++ Y F
Sbjct: 6833 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEG-QEYSF 6891
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV+A N IG + S + + +P + L+ + T +SV ++W+PP +D + I
Sbjct: 6892 RVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPI 6951
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
L G+ + W P LT Y++ L K
Sbjct: 6952 L----------------GYIIERCEEGKDNWIRCNMKLV------PELT-YKVTGLEKGN 6988
Query: 1594 RYEIRMSVYNAVGEGPSSP------PQEVFVGEAVPTAAPRN---VVVHGATATQLDVTW 1644
+Y R+S N G S + FV + +A ++ V+V + T
Sbjct: 6989 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7048
Query: 1645 EPPPLDSQN-GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAF 1703
P P + GD K L + VK+K L+ Y ++S +
Sbjct: 7049 YPRPTATWCFGD--------------------KVLETGDR-VKMKTLSAYAELVISPSER 7087
Query: 1704 NAAGDGPRSTPTQGQTQQ--------AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-L 1754
+ G + +T A PSAP +KF ++T SV+++WE P G L
Sbjct: 7088 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7147
Query: 1755 EGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP---- 1810
GY + S K T + + L V DL +G Y F++ A+ GP
Sbjct: 7148 TGYVVEKREVS-----RKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARN-KCGPGEPA 7201
Query: 1811 EIEANVTTGPGEGAPGPP-GVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGL 1868
++ V P PP V R +++I + W + G I Y++E P
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7261
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYE 1928
W + V+ + L+ G Y +RV A+N G PS P++ + A E
Sbjct: 7262 W----VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7317
Query: 1929 EWWFLVVIALVGL 1941
FL V L GL
Sbjct: 7318 --IFLDVKLLAGL 7328
Score = 127 bits (320), Expect = 9e-29
Identities = 317/1464 (21%), Positives = 519/1464 (35%), Gaps = 187/1464 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVID------G 416
++ GL+ + F+ A N GE + LA + IA +I P LD T D G
Sbjct: 11493 RVPGLIEGNEYRFRIKAANIVGEGEPRE-LAESVIAKDILHPPEVELDVTCRDVITVRVG 11551
Query: 417 MSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
++ + G P P ITW K ++L ++ L L I +D G Y
Sbjct: 11552 QTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11610
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
A NS G + SA + V R P Q+ V T+ + C ++ WE
Sbjct: 11611 AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKEN--CTIS----------WENPLD 11655
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV---RQLPHAP 593
G+E I R + + WS T R+I A + + RV ++ P
Sbjct: 11656 NGGSEITNFIVEYRKPN---QKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGP 11712
Query: 594 ----EHPVATLSTVERRA--------------INLTWTKP-FDGNSPLIRYILEMSENNA 634
+ P+ ++ ++R + L W +P +DG SP + Y +E +
Sbjct: 11713 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11772
Query: 635 PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE---PPT 691
+ K T V V + Y+FR+ N+ G+ + K TE V + E+ P
Sbjct: 11773 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TEEVVVKEDLQKPVL 11831
Query: 692 APPQNVIASGRTNQSIM----IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
+ + + + +I ++ +P PE + L + K T A
Sbjct: 11832 DLKLSGVLTVKAGDTIRLEAGVRGKPFPE-------VAWTKDKDATDLTRSPRVKIDTRA 11884
Query: 748 DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
D + L + V A N+AG V + V G P N+ +S
Sbjct: 11885 DSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG----PVRNLKIVDVSSDR 11940
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W+ P + G ++ + E+ E MV + + V+ L + EY
Sbjct: 11941 CTVCWDPPED------DGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY 11994
Query: 868 FTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
V G GP S P + +T D PG +++ + V W P G
Sbjct: 11995 IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKS 12054
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS--AS 982
+TGY + +E + T + +V L Y V A G G+ S +
Sbjct: 12055 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 12114
Query: 983 TISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVE--AQVGVVGEGE 1039
+ + P E PGPPTN + + S+TL + +P YDG I ++VE ++ E
Sbjct: 12115 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDE 12174
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
W + + + + V L+ Y FR+ N VG P++ I+ + +
Sbjct: 12175 GWKRCNAAA-QLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI---LE 12230
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD 1159
P + L + + +R G P + ++ G+ V +V D
Sbjct: 12231 PPEIDLDASMRKLVIVR---------AGCPIRLFAIVR-------GRPAPKVTWRKVGID 12274
Query: 1160 YTIE----DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRES--------VPSSGP-TNV 1206
+ DL + + V + SG +S T+V E + + GP +++
Sbjct: 12275 NVVRKGQVDLVDTMAFLV-IPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 12333
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGL 1266
T +S V W+ PE D V Y V +E D T + S +T L
Sbjct: 12334 KVSDVTKTSCHVSWAP-PENDGGSQVTHYIVEKREADRKTWST--VTPEVKKTSFHVTNL 12390
Query: 1267 GKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
Y +V A G G P+ P+L P PP + E+ S L W PP
Sbjct: 12391 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 12450
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
G + IT E TGLK Y FR+ A+ G
Sbjct: 12451 LRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS 12510
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL-------------LSWEPGSDGLSP 1431
EA V E +++ PP M +Q ++A L W+ G D +
Sbjct: 12511 LPREAEGV-YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEV-- 12567
Query: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491
+ S A+H A ++S I+ + S + + A N G ++
Sbjct: 12568 ----------VTSSHLAVHKAD---SSSILIIKDVTRKDSGYYSLTAENSSG----TDTQ 12610
Query: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG 1551
+ + AP ++ + + W P ED + I
Sbjct: 12611 KIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNI----------------TN 12654
Query: 1552 FTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGP 1609
+ + + W +T++ S+ + T + L + Y R+ N G E
Sbjct: 12655 YIVEKCDVSRGDW--VTALASV------TKTSCRVGKLIPGQEYIFRVRAENRFGISEPL 12706
Query: 1610 SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQR 1668
+SP VP + P+N V + V W+ P DS G I GY I E +
Sbjct: 12707 TSPKMVAQFPFGVP-SEPKNARVTKVNKDCIFVAWDRP--DSDGGSPIIGYLIERKE-RN 12762
Query: 1669 GNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPS 1728
L + + L Y + A N AG P S PT+ T + P
Sbjct: 12763 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG 12822
Query: 1729 SVKFSELTTTSVNVSWEAPQFPNG 1752
+ ++T ++V++ W P+ G
Sbjct: 12823 KPEVIDVTKSTVSLIWARPKHDGG 12846
Score = 127 bits (319), Expect = 1e-28
Identities = 190/818 (23%), Positives = 304/818 (37%), Gaps = 69/818 (8%)
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER-DYTIEDLEEW-TEYRVQVQAFNAIGS 1183
+G + +GY ++ R D KT + DR E ++T+ L++ EY +V A N +G+
Sbjct: 6744 DGGSKIIGYVVE--RRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGT 6800
Query: 1184 GPWSQT---VVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYK 1240
G +T V R++ VP P NV+ + + W E PE D + Y + +
Sbjct: 6801 GEPVETDNPVEARSKYDVPGP-PLNVTITDVNRFGVSLTW-EPPEYDGGAEITNYVIELR 6858
Query: 1241 EKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDV 1300
+K S V SA +T + + Y +V A RIG G PS + D +
Sbjct: 6859 DKTSIRWDTAMTVRAEDL-SATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPI 6917
Query: 1301 --PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P PP+ + + +SV+L W+PP G + I R N +
Sbjct: 6918 ERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPEL 6977
Query: 1359 QYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE--DVRAR 1416
Y TGL+ + YL+R++A+ + G + +E L T +P ++ +V
Sbjct: 6978 TYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVP 7037
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFR 1475
+ + P + P + + L +G R + + S + ++ + +
Sbjct: 7038 NPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAY---AELVISPSERSDKGIYT 7094
Query: 1476 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 1535
+K N + S + A AP L T SV + W+PP +D L
Sbjct: 7095 LKLENRV-----KTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDG-GSPLT 7148
Query: 1536 GFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRY 1595
G+ + RE+ + TW ++ + + P L Q + Y
Sbjct: 7149 GYVVEKREVSRK---------------TWTKVMDFVTDLEFTVPDLVQ--------GKEY 7185
Query: 1596 EIRMSVYNAVGEGPSS---PPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQ 1652
++ N G G + P + VP P NV TA + +TW+PP D
Sbjct: 7186 LFKVCARNKCGPGEPAYVDEPVNMSTPATVPDP-PENVKWRDRTANSIFLTWDPPKNDG- 7243
Query: 1653 NGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712
I+GY + RG+ +AE +++ L Y V A N G S
Sbjct: 7244 GSRIKGYIVE--RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPS 7301
Query: 1713 TPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDG 1769
PT Q Q AP VK T E P G E ++ + +
Sbjct: 7302 RPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP-KITWTKADMILK 7360
Query: 1770 VSKIVTVD-VKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPP 1828
K +T++ V S + + ++ TY +E NV PG P
Sbjct: 7361 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGP----PA 7416
Query: 1829 GVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSM 1887
I + + + W+ D G IT YV+E R +D +W L V F
Sbjct: 7417 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL----SSTVKDTNFKA 7472
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
L P Y FRV A N YG G P S + +P
Sbjct: 7473 TKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDP 7510
Score = 124 bits (311), Expect = 1e-27
Identities = 299/1315 (22%), Positives = 478/1315 (36%), Gaps = 170/1315 (12%)
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
VS+ + P PP N + S++ +W+PP + + I I Y L + K
Sbjct: 8424 VSVLDTP--GPPINFVFEDIRKTSVLCKWEPPLDDGGSEI-----INYTL-------EKK 8469
Query: 743 NITDADVNNLLLED-----------LIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQG 789
+ T D +++ LI Y V A N G G S + G
Sbjct: 8470 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFG 8529
Query: 790 VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN- 848
P P + + T+++ + WN P + G ++ + E+ E + +R N
Sbjct: 8530 PPDAPDKPIVEDVTSNSML-VKWNEPK-------DNGSPILGYWLEKREVNSTHWSRVNK 8581
Query: 849 -FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
+++ V GL + Y V G G S P +T D P G +
Sbjct: 8582 SLLNALKAN-VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGP-PIPRVT 8639
Query: 908 DTS---LKVSWQEPG-EKNGILTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTAL 961
DTS +++ W+ P G + GY + ++ TN +R T + V +Y V +
Sbjct: 8640 DTSSTTIELEWEPPAFNGGGEIVGYFVD-KQLVGTNEWSRCTEKMIKVR-QYTVKEIREG 8697
Query: 962 TTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV----TLQFRPGY 1017
Y + V+A+ + G+G + + P+ P P L +S G + TL+
Sbjct: 8698 ADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP-PAVELDVSVKGGIQIMAGKTLRIPAVV 8756
Query: 1018 DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G+ V +V EGE + N + + D + + N
Sbjct: 8757 TGRP------VPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSC 8810
Query: 1078 GTSPPSQPSRKIQTLQAPP---DMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY 1134
G+ + +++ P D+ P + L W + E +G E G+
Sbjct: 8811 GSK---FAAARVEVFDVPGPVLDLKPV-----VTNRKMCLLNWS---DPEDDGGSEITGF 8859
Query: 1135 KIKYSRSDGHGKTLSHVVQ-DRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
I+ R D T ++ +R + D T L E EY+ +V A N G GP +G
Sbjct: 8860 IIE--RKDAKMHTWRQPIETERSKCDIT--GLLEGQEYKFRVIAKNKFGCGP--PVEIGP 8913
Query: 1194 TRESVPSSGPTNVSALA---TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRF 1250
P PT+ L T S++ + W E P ++ + GY + EK +P F
Sbjct: 8914 ILAVDPLGPPTSPERLTYTERTKSTITLDWKE-PRSNGGSPIQGYII---EKRRHDKPDF 8969
Query: 1251 WLVEGN--SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGIL 1308
V + S + L ++ +YE +V A IG+ PS P L + D PP L
Sbjct: 8970 ERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLP--LNVVIQDDEVPPTIKL 9027
Query: 1309 FPEVRTTSVRL-IWQP---PAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
VR ++++ +P PA G+ + +I N T T + L + + + +
Sbjct: 9028 RLSVRGDTIKVKAGEPVHIPADVTGLPMP-KIEWSKNETVIEKPT-DALQITKEEVSRSE 9085
Query: 1365 LK-----PESVY----LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRA 1415
K P++V + +TA R G + V E DRP PP V D++A
Sbjct: 9086 AKTELSIPKAVREDKGTYTVTASNRLG----SVFRNVHVEVYDRPSPPRNLAVT--DIKA 9139
Query: 1416 RSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S L+W+ P +G S + +Y I R+ + + + + + +L P Y+F
Sbjct: 9140 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 9199
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGIL 1534
RV+A N G S+ + + + P V T S+L+ W PP D +
Sbjct: 9200 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSPI 9258
Query: 1535 LGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSL--TQYELDNLNKH 1592
G+ + RE EG + S S +++ L ++ + L +
Sbjct: 9259 TGYWLEKRE---EG----------------SPYWSRVSRAPITKVGLKGVEFNVPRLLEG 9299
Query: 1593 RRYEIRMSVYNAVGEGPSSPPQ--EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+Y+ R NA G GP S P EV P P V T + + + W+PP D
Sbjct: 9300 VKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKD 9359
Query: 1651 SQNGDIQGYKIYFWE---AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG 1707
I+GY + E + E K + E V NL Y V A N AG
Sbjct: 9360 G-GSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVV--PNLKELRKYRFRVKAVNEAG 9416
Query: 1708 DGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
+ S T Q P + + P G R +
Sbjct: 9417 ESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG-----RPTPKSS 9471
Query: 1765 SPVDGVSKIVTVDVKGNSP-----------LWLKVKDLAEGVTYRFRIRAKTFTYGPEIE 1813
DG +K D + P + + + T ++ I AK
Sbjct: 9472 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 9531
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGLWDIL 1872
V G P V I R S ++ W D G I YVIE R D W
Sbjct: 9532 CRVKVMDVPGPPKDLKVSDITRGSCRLS--WKMPDDDGGDRIKGYVIEKRTIDGKAW--- 9586
Query: 1873 IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFY 1927
+ + S TF + L Y FRV A N +G G P Q A+ +P Y
Sbjct: 9587 -TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR--DPIY 9638
Score = 122 bits (307), Expect = 3e-27
Identities = 293/1394 (21%), Positives = 498/1394 (35%), Gaps = 169/1394 (12%)
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P T T + + +L W+ P DG S + YI+E E + + T
Sbjct: 10049 PPGPPFPKVTDWT--KSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10106
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ V GL Y+FR+ AVN G G+ + T+ + + + +P + AS R +
Sbjct: 10107 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-VSPDLQLDASVRDRIVV- 10164
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLP---VGYQFKNIT---DADVNNLLLEDLIIWTN 762
H G+++ II Y ++G P V + T +A + + ++ N
Sbjct: 10165 ---------HAGGVIR--IIAY-VSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKN 10212
Query: 763 YE------IEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
+ + A N AG + V + G P P H TN + + TW +P
Sbjct: 10213 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAH-NLTNESC-KLTWFSPE 10269
Query: 817 PQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
+ I Y + E ++ VT R N V GL + YF +
Sbjct: 10270 DDGGSPITN-YVIEKRESDRRAWTPVTYTVTRQN-------ATVQGLIQGKAYFFRIAAE 10321
Query: 875 TTPGDGP---RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG------IL 925
+ G GP S ++R VP L E+ ++ ++W P G +L
Sbjct: 10322 NSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 10381
Query: 926 TGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
I E++++ TN + ++ +Y V GL TY V+A+ GQG+ S T
Sbjct: 10382 ESRLIGTEKFHKVTNDNL------LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTK 10435
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFRPG--------YDGKTSISRWLVEAQVGVVG 1036
EL P +L + L R G Y GK + + V+
Sbjct: 10436 PITCKDELAPPTLHLDFRD------KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489
Query: 1037 EGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP- 1095
+ + P ++E + + N G+ + ++ + P
Sbjct: 10490 DDRT-----HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSR---KGFCQVNVVDRPG 10541
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL-SHVVQD 1154
P + P VS ++ + + W P + +G + Y I+ GK + V
Sbjct: 10542 PPVGP--VSFDEVTKDYMVISWKPPLD---DGGSKITNYIIEKKEV---GKDVWMPVTSA 10593
Query: 1155 RVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTRESVPSSGPTNVSALATT 1212
+ + L E +Y ++ A N G S P S ++ + R VP + P T
Sbjct: 10594 SAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDA-PDQPIVTEVT 10652
Query: 1213 SSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLY 1272
S LV W++ + + + Y + +E S R + ++ L + Y
Sbjct: 10653 KDSALVTWNKPHDGGKP--ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 10710
Query: 1273 EVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
E +V A IG G PS P P+ + P PP+ + SV L WQPP G
Sbjct: 10711 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10770
Query: 1331 -ILAYQITH-RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE 1388
IL Y + + ++ A + +Y TGL+ Y FR+ A G + A
Sbjct: 10771 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 10830
Query: 1389 ALVVTTEKRDRPQPPS----RPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPS 1444
K DR +PP M +++ ++ L LS + I+ P
Sbjct: 10831 VPEPVLVK-DRLEPPELILDANMAREQHIKVGDTLR--------LSAI----IKGVPFPK 10877
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIG------DSEFSEESESLTTLQ 1498
W A +D + + R A D G ++ ++ S+ L
Sbjct: 10878 VTWKKEDRDAPTKAR---IDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV 10934
Query: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558
P L V+ S + W+ P +D ++ + + R++
Sbjct: 10935 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDG-GSVITNYVVERRDVA------------- 10980
Query: 1559 NPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP--SSPPQEV 1616
A W+ L++ ++ + +LN+ +Y R++ N G GP +P
Sbjct: 10981 --SAQWSPLSATSKKKS--------HFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIK 11030
Query: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVK 1676
+ P P+++ T++ + W P D I GY + E Q + +K
Sbjct: 11031 ALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDG-GSPITGYLV---EYQEEGTQDWIK 11086
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST--PTQGQTQQAAPSAPSSVKFSE 1734
+ + L Y V A N G G T P + Q + PS VK E
Sbjct: 11087 FKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIE 11146
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+ P G+ S + + TV+ S + L +K+
Sbjct: 11147 GLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTVETDNFSSV-LTIKNCLRR 11204
Query: 1795 VTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGK 1851
T ++I + ++T PGPP PI + + + I W D G
Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTV---LDVPGPPTGPINILDVTPEHMTISWQPPKDDGG 11261
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
P+ Y++E + + + W + + S + L+ G Y FRV A N G G P
Sbjct: 11262 SPVINYIVEKQDTRKDTWGV----VSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPP 11317
Query: 1912 SSPSQSVPAQKANP 1925
+ +V K +P
Sbjct: 11318 LDSTPTVAKHKFSP 11331
Score = 119 bits (299), Expect = 2e-26
Identities = 335/1620 (20%), Positives = 584/1620 (36%), Gaps = 266/1620 (16%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAK--------GVPPPSITWYKDAAVVEVEK 353
++ +EP + ++ P+ + +++K V I A G PPP ITW K +
Sbjct: 23060 IAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA 23119
Query: 354 LTRFRQRNDGGLQISGLVPD-----DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP 408
+ D S L+ D D G + A N +G+ + + V T GP
Sbjct: 23120 II------DTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD-----TPGP 23168
Query: 409 LDSTVI-----DGMSVVLACET--SGAPRPAITWQKGER-------ILASGSVQLPRFTP 454
S + D +++ T GAP +K E + S L R +
Sbjct: 23169 CPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISG 23228
Query: 455 LESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQAS 514
L G++ + L N G+ E + + P V+ T++
Sbjct: 23229 LVEGTMYY----------FRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKS- 23277
Query: 515 MVCGVTHDPRVTIRYIWEK---DGAT-----------LGTESHPRIRLDRNGSLHISQTW 560
T+ WEK DG + GTE ++ + L + T
Sbjct: 23278 -----------TVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTS 23326
Query: 561 SGDIGTYTCRVISA---GGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD 617
+ Y R+ + G ++ R V + P LST+ ++ I++ +P +
Sbjct: 23327 LNEGEQYLFRIRAQNEKGVSEPRETVTAVT-VQDLRVLPTIDLSTMPQKTIHVPAGRPVE 23385
Query: 618 GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGK---- 673
L+ I A W S ++ VTV+ R + D G+
Sbjct: 23386 ----LVIPIAGRPPPAASW-FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23440
Query: 674 -----GQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII 728
G S+ + + L + P P + T SI I W+PP E L GY++
Sbjct: 23441 LKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDAT--SITISWEPP-ELDGGAPLSGYVV 23497
Query: 729 RYCLAG----LPVG-------YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
A LPV ++F +T+ + Y VAA N G+G
Sbjct: 23498 EQRDAHRPGWLPVSESVTRSTFKFTRLTEGN-------------EYVFRVAATNRFGIGS 23544
Query: 778 Y-SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGY-------KL 829
Y S+V E PP + + + TW P + + GY +
Sbjct: 23545 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRA 23603
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
W + VTM R +GL + EY V G G S P
Sbjct: 23604 DRWVRVNKVPVTMTRYRS-----------TGLTEGLEYEHRVTAINARGSGKPSRPSKPI 23652
Query: 890 THEDVPGPVGHLSFSEILDT---SLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
D P G + DT S+ ++W P ++ G +TGY I ++ ++ +
Sbjct: 23653 VAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT 23712
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLG----- 1000
P EY +T L Y V A + G G+ + + V L P L
Sbjct: 23713 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 23772
Query: 1001 ---ISNIGPRSVTLQFRPGYDGKT-SISRWLVEAQ------VGVVGEGEEWLLIHQLSNE 1050
+ G +T+ + GK I +W E Q + E L+I + ++
Sbjct: 23773 GIFVRQGGVIRLTIPIK----GKPFPICKWTKEGQDISKRAMIATSETHTELVIKE-ADR 23827
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110
D+ + ++ N + ++ V ++G+ P+ P ++ ++ +R
Sbjct: 23828 GDSGTYDLVLENKCGKKAVYIK-VRVIGS--PNSPEGPLEY---------DDIQVR---- 23871
Query: 1111 TSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE-RDYTIEDLEEWT 1169
S+ + W P + +G + +GY ++ K + + RV ++ L+E
Sbjct: 23872 -SVRVSWRPPAD---DGGADILGYILERREVP---KAAWYTIDSRVRGTSLVVKGLKENV 23924
Query: 1170 EYRVQVQAFNAIG-SGPWS--QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 1226
EY +V A N G S P + V +T + P L T SS+ + WS P+
Sbjct: 23925 EYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSR-PKD 23983
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG--D 1284
D V GY + KE +D R + ++ +TGL Y+ +++A +G +
Sbjct: 23984 DGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYT-VTGLVPDAEYQFRIIAQNDVGLSE 24042
Query: 1285 GSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTT 1343
SP+ P++ + D P P + + SV L W+ P G IL Y + +R +
Sbjct: 24043 TSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGD 24102
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE-ALVVTTEKRDRPQP 1402
+A + + +Q+T GL + Y FR+ A+ G A+ + T+ P
Sbjct: 24103 SAWKKSNKERIKD-KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP 24161
Query: 1403 PSRPMVQQEDVR-ARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF 1461
R ++ + + LS + L +++Y + S ++ + S +H +
Sbjct: 24162 GIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVM 24221
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 1521
++ + ATN++G+ E S S LQA P P
Sbjct: 24222 TEEQEDEGV---YTCIATNEVGEVETS----SKLLLQATPQFHPGY-------------- 24260
Query: 1522 WQPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATWAELTSMY-SMR 1574
P ++K Y G G TLR G P TW + +
Sbjct: 24261 ---PLKEK----------------YYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24301
Query: 1575 NLSRPSLTQYE---LDNLNKHR---RYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPR 1628
N++ + Y + N+ + +Y++++S N G + E+ PT
Sbjct: 24302 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLS--NVFGTVDAILDVEIQDKPDKPTGP-- 24357
Query: 1629 NVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLK 1688
+V+ ++W+PP D I Y + EA+ G + V + ++ + ++
Sbjct: 24358 -IVIEALLKNSAVISWKPPA-DDGGSWITNYVVEKCEAKEGAEWQLVSSA-ISVTTCRIV 24414
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPR---STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
NLT Y V+A N G S+ ++ P AP + +T S V+W+
Sbjct: 24415 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK 24474
Query: 1746 APQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
P G + Y L +K ++V + VK+L EG+ Y FR++ +
Sbjct: 24475 PPASDGGAKIRNYYLEKREKKQ----NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCE 24530
Score = 115 bits (288), Expect = 5e-25
Identities = 161/653 (24%), Positives = 252/653 (38%), Gaps = 89/653 (13%)
Query: 1299 DVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN--TATVEVLAP 1355
D PGPP ++ + L W P G + I + + + + TA V
Sbjct: 12618 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKT 12677
Query: 1356 SARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP---PSRPM-VQQE 1411
S R L P Y+FR+ A+ R G E +T+ K P PS P +
Sbjct: 12678 SCR---VGKLIPGQEYIFRVRAENRFGISEP-----LTSPKMVAQFPFGVPSEPKNARVT 12729
Query: 1412 DVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFT 1470
V + ++W+ P SDG SP+ Y I+ +E S W + ++ + + + L
Sbjct: 12730 KVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRS-TEYPCAGLVEGL 12788
Query: 1471 SYKFRVKATNDIGDSEFSEESESLTT-LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK 1529
Y FR+ A N G S S+ +E +T + P P ++ VT T + + W P D
Sbjct: 12789 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLI---WARPKHDG 12845
Query: 1530 INGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQ--YELD 1587
+ I+ G+ + PG W N + + Q Y
Sbjct: 12846 GSKII----------------GYFVEACKLPGDKWVRC-------NTAPHQIPQEEYTAT 12882
Query: 1588 NLNKHRRYEIRMSVYNAVGEGPSSPPQE--VFVGEAVPTAAPRNVV------VHGATATQ 1639
L + +Y+ R AV P S P + + E VP +V V T
Sbjct: 12883 GLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVC 12942
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
LD T P+ + + G + E + + + TL L SV K+ YT
Sbjct: 12943 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGDYT----- 12995
Query: 1700 VAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
+ A N++G + + + P P+SVK +++ + +SWE P G + Y
Sbjct: 12996 ITAENSSGSKSATIKLKVLDK---PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG--------P 1810
+ S + TV + S V+ L EG Y+FRI A+ YG P
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCS-----VEKLIEGHEYQFRICAEN-KYGVGDPVFTEP 13106
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSA-IAIHWSS-GDPGKGPITRYVIEARPSDEGL 1868
I N PG P P+I + + + W D G PIT Y++E R +
Sbjct: 13107 AIAKNPYDPPGRCDP-----PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 13161
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
W + + K + T L+ G Y+FRV A+N G G PS S++ A+
Sbjct: 13162 WTKVNR---KPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYAR 13211
Score = 114 bits (285), Expect = 1e-24
Identities = 351/1625 (21%), Positives = 576/1625 (35%), Gaps = 260/1625 (16%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARN 384
V+IP G P P++TW K +++ + F L I+ V D+G + ARN
Sbjct: 14713 VEIP--VLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14770
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILAS 444
GEV + V I P GP+ + V +W E
Sbjct: 14771 IVGEVGDVITIQVHDI-PGPPTGPIKFDEVSSDFV------------TFSWDPPEN---D 14814
Query: 445 GSVQLPRF----------TPLESGSLLISPTHISDAGT------YTCLATNSRGVDE--A 486
G V + + T +E + +I T+ + T + A N GV
Sbjct: 14815 GGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 14874
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
SA +V ++ PP V T+ SM H+P DG + H
Sbjct: 14875 SACIVANYPFKVPGPPGTPQVTAVTKDSMTIS-WHEPL--------SDGGSPILGYHVE- 14924
Query: 547 RLDRNGSLHISQTWS-----GDIGTYTCRVISAGGNDSRSAHLRV-------RQLPHAPE 594
R +RNG L QT S G+I S+G D + RV + P P
Sbjct: 14925 RKERNGILW--QTVSKALVPGNI------FKSSGLTDGIAYEFRVIAENMAGKSKPSKPS 14976
Query: 595 HPVATLSTVE-----------RRAINLTWTKP-FDGNSPLIRYILEMSE-NNAPWTVLLA 641
P+ L ++ R + L W KP + G + YI+E + N W
Sbjct: 14977 EPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 15036
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
S + TV GL +Y+FR+ A N G + + AP V
Sbjct: 15037 S-NILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKF 15095
Query: 702 RTNQSIM----------IQWQPPPE---SHQNGILKGYIIRYCLAGLPVGYQFKNITDAD 748
+ + + +PPP S L+G A L + I D
Sbjct: 15096 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEG------TAKLEI-----KIADFS 15144
Query: 749 VNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
NL+ +D + + A N G +++ KV + P P G + S
Sbjct: 15145 -TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLD-----RPGPPEGPLAVTEVTSE 15198
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTE 866
+W P + G K+ + ++ E + + + V+ L K E
Sbjct: 15199 KCVLSWFPPLD------DGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 15252
Query: 867 YFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y V+ G G S P L P P + + I S+ V W P G
Sbjct: 15253 YIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS 15312
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + + + L Y+V+GLT Y + A + G +SA +
Sbjct: 15313 EIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAG---ISAPS 15369
Query: 984 ISSGVPPEL-----PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+S PGPP N + + S+++ + +P YDG + I+ ++VE + E
Sbjct: 15370 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEI---ALPE 15426
Query: 1038 GEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPS--QPSRKIQTLQAP 1095
+EW ++ + A S + L Y R+ +N G P+ + K + P
Sbjct: 15427 EDEWQIVTPPAG-LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 15485
Query: 1096 PDM-----APANVSLRTASETSLW--LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
P++ V++R L+ ++ P PE +K++R HG++L
Sbjct: 15486 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-------------VKWARD--HGESL 15530
Query: 1149 SHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSA 1208
+IE +T + V N SG + TV S S NV
Sbjct: 15531 DKA---------SIESTSSYT--LLIVGNVNRFDSGKYILTV---ENSSGSKSAFVNVRV 15576
Query: 1209 LAT------------TSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN 1256
L T T +S+ + W + P D + Y V EK T+ + V N
Sbjct: 15577 LDTPGPPQDLKVKEVTKTSVTLTW-DPPLLDGGSKIKNYIV---EKRESTRKAYSTVATN 15632
Query: 1257 SSRSA-QLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT 1315
+++ ++ L + Y +VLA G G P+ + + P PP I +V
Sbjct: 15633 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA-SERPLPPGKITLMDVTRN 15691
Query: 1316 SVRLIWQPPAAPNGI-ILAY--QITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
SV L W+ P G IL Y ++ + + A ATV+V + T TGL Y
Sbjct: 15692 SVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKV-----TEATITGLIQGEEYS 15746
Query: 1373 FRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-------VQQEDVRARSVLLSWEPG 1425
FR++AQ KG + + L V +D PP+ + + ED++ +
Sbjct: 15747 FRVSAQNEKGISDPRQ-LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG---- 15801
Query: 1426 SDGLSPVRYYTIQTRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGD 1484
P T +P + +++ S +N+ I D + + + VK TN G
Sbjct: 15802 ----RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGH-YVVKLTNSAG- 15855
Query: 1485 SEFSEESESLTTLQAAPDEAPT-ILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRE 1543
E E+L + PT + + T S+ + W PP D + I
Sbjct: 15856 ----EAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSI---------- 15901
Query: 1544 LLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
+ + + TW +++ + T + L Y+ R++ N
Sbjct: 15902 ------NNYIVEKRDTSTTTWQIVSATVAR--------TTIKACRLKTGCEYQFRIAAEN 15947
Query: 1604 AVGEGP--SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKI 1661
G+ +S P VP P VV ++ ++V W P D + GY +
Sbjct: 15948 RYGKSTYLNSEPTVAQYPFKVP-GPPGTPVVTLSSRDSMEVQWNEPISDG-GSRVIGYHL 16005
Query: 1662 YFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQ 1721
E + L ++ + + K L Y V+A N G G S ++ +
Sbjct: 16006 ERKE-RNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVAR 16064
Query: 1722 AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKG 1780
P + +T SV + W+ P + G + GY +V + P K ++
Sbjct: 16065 DPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGY-IVEKKELPEGRWMKASFTNIID 16123
Query: 1781 NSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTG--PGEGAPGPPGVPIIVRYSS 1838
+V L E Y FR+ A+ G E + +TG PP + + +Y
Sbjct: 16124 TH---FEVTGLVEDHRYEFRVIARN-AAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16179
Query: 1839 AIAIH 1843
I +H
Sbjct: 16180 TIVVH 16184
Score = 105 bits (263), Expect = 4e-22
Identities = 280/1353 (20%), Positives = 493/1353 (36%), Gaps = 159/1353 (11%)
Query: 621 PLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT 680
P + + + +AP T V P + + ++ + L N G S
Sbjct: 10874 PFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSV-- 10930
Query: 681 ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQ 740
+V + ++P PP+++ S S + W+ P + + I + R +A Q
Sbjct: 10931 -KVLVLDKP--GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASA----Q 10983
Query: 741 FKNIT-DADVNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGN 797
+ ++ + + + L Y VAA N G G V + K + P PP +
Sbjct: 10984 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11043
Query: 798 VHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF 857
+H + T + WN P + I GY L+ ++ E ++ N +
Sbjct: 11044 LHHVDVDKTEVSLVWNKPDRDGGSPIT-GY-LVEYQEEGTQDWIKFKTVTNLEC-----V 11096
Query: 858 VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVS--- 914
V+GL++ Y V G G T + E + P L I +K
Sbjct: 11097 VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTV 11156
Query: 915 ---------------WQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLT 959
W G + Y + + ++ T + + L T EY++T
Sbjct: 11157 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT-IKNCLRRDTGEYQITVSN 11215
Query: 960 ALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN-LGISNIGPRSVTLQFRPGYD 1018
A + T+ V ++PGPPT + I ++ P +T+ ++P D
Sbjct: 11216 AAGSKTVAVHLTVL-----------------DVPGPPTGPINILDVTPEHMTISWQPPKD 11258
Query: 1019 -GKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G + + ++VE Q + W ++ S++ +++P L Y FR+R N +
Sbjct: 11259 DGGSPVINYIVEKQDT---RKDTWGVVSSGSSKT---KLKIPHLQKGCEYVFRVRAENKI 11312
Query: 1078 GTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIK 1137
G PP + + + P P + +E + + W LP+ + G GY ++
Sbjct: 11313 GVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSD--GGSPITGYYME 11369
Query: 1138 YSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTR 1195
R + GK + + + + L E Y +V A N G S P S + R
Sbjct: 11370 --RREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR 11427
Query: 1196 ESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG 1255
P P N + + + W++ P +D +LGY V ++ + R E
Sbjct: 11428 PIKPPGPPINPKLKDKSRETADLVWTK-PLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11486
Query: 1256 NSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVR 1313
+ ++ GL + Y ++ A +G+G P ++ + + P + + +V
Sbjct: 11487 IRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVI 11546
Query: 1314 TT----SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPES 1369
T ++R++ + P I + ++ ++ L Q
Sbjct: 11547 TVRVGQTIRILARVKGRPEPDI-TWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605
Query: 1370 VYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDG 1428
Y+ I+A+ G + + + V DRP P V +V + +SWE P +G
Sbjct: 11606 KYI--ISAKNSSGHAQGSAIVNVL----DRPGPCQNLKVT--NVTKENCTISWENPLDNG 11657
Query: 1429 LSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 1488
S + + ++ R+ W++ ++ V+ I L Y FRV A N +G
Sbjct: 11658 GSEITNFIVEYRKPNQKGWSIVASDVTKR---LIKANLLANNEYYFRVCAENKVGVGPTI 11714
Query: 1489 EESESLTTLQAA--PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLY 1546
E + + P E P L + T V ++W+ P D L + + R
Sbjct: 11715 ETKTPILAINPIDRPGE-PENLHIADKGKTFVYLKWRRPDYDG-GSPNLSYHVERR---- 11768
Query: 1547 EGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG 1606
L+G ++ W E S++ T Y +D +++ YE R+ N G
Sbjct: 11769 -------LKGSDD----W-ERVHKGSIKE------THYMVDRCVENQIYEFRVQTKNEGG 11810
Query: 1607 EGPSSPPQEVFVGEAVPT-------AAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGY 1659
E +EV V E + + V + V +P P + D
Sbjct: 11811 ESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDAT 11870
Query: 1660 KIYFWEAQRGNLTERVKTLFLAENS----VKLKNLTGYTAYMVSVAAFNAAGDGPRSTPT 1715
+ + RVK A++S K K G Y+V+ A N AG
Sbjct: 11871 DL--------TRSPRVKIDTRADSSKFSLTKAKRSDG-GKYVVT--ATNTAGSFVAYATV 11919
Query: 1716 QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV--SKI 1773
+ P ++K ++++ V W+ P+ G E + E C V +
Sbjct: 11920 NVLDK---PGPVRNLKIVDVSSDRCTVCWDPPEDDGGC-EIQNYILEKCETKRMVWSTYS 11975
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGE----GAPGPP 1828
TV G + V L EG Y FR+RA+ GP E+ + G P PP
Sbjct: 11976 ATVLTPGTT-----VTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPP 12030
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
V + + + + D GK IT Y +E + W + K + +
Sbjct: 12031 EVTKVSKEEMTVVWNPPEYDGGKS-ITGYFLEKKEKHSTRWVPVNKSA---IPERRMKVQ 12086
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
L P Y FRV A N+ G G PS PS+ V A+
Sbjct: 12087 NLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 12119
Score = 100 bits (248), Expect = 2e-20
Identities = 154/690 (22%), Positives = 263/690 (38%), Gaps = 56/690 (8%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRA- 134
+ +TSLD +R +N++G + + + E E S + ++RA
Sbjct: 12190 FTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAG 12249
Query: 135 ------PRIASFPQPQVTWFRDG--RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAV 186
+ P P+VTW + G + + LVI ++ D+G+Y + V
Sbjct: 12250 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLV 12309
Query: 187 NDKNGDNKTSQPITLTVENVGGPADPIAPTIII---------PPKNTSVVAGTSEVTLEC 237
N + + + + V + GP + + + PP+N T + +
Sbjct: 12310 NPAG---EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKR 12366
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI--SDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPS 295
A+ + + KK ++ + +++ R+T N G + VL S
Sbjct: 12367 EADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP--- 12423
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPS--ITWYKDAAVVEVEK 353
LS +PP+ ++ E +T + +P G IT Y++ ++
Sbjct: 12424 ------LSEPDPPRKLEVTE--MTKNSATLAWLPPLRDGGAKIDGYITSYREEEQ-PADR 12474
Query: 354 LTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIAPNITRGPL 409
T + D L ++GL F+ ARNA G Y A + P P
Sbjct: 12475 WTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPE 12534
Query: 410 DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
T+ G + + G P P W+KGE + + S L S L+I D
Sbjct: 12535 QITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS-HLAVHKADSSSILIIKDVTRKD 12593
Query: 470 AGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--I 527
+G Y+ A NS G D +VV +PP D S I S+ + + +
Sbjct: 12594 SGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 12653
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG-NDSRSAHLRV 586
YI EK + G + + S + + G + R + G ++ ++ V
Sbjct: 12654 NYIVEKCDVSRGDWVTALASVTKT-SCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 12712
Query: 587 RQLPHA-PEHPV-ATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
Q P P P A ++ V + I + W +P DG SP+I Y++E E N+ V
Sbjct: 12713 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 12772
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS--LPEEPPTAPPQNVIASG 701
++T GLV Y FR+ A+N G SK TE V+ +P +PP P +
Sbjct: 12773 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDV--- 12829
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYC 731
T ++ + W P + I+ GY + C
Sbjct: 12830 -TKSTVSLIWARPKHDGGSKII-GYFVEAC 12857
Score = 94.0 bits (232), Expect = 1e-18
Identities = 163/705 (23%), Positives = 268/705 (38%), Gaps = 83/705 (11%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHA-----------GFY 89
G L+C G + KW +EL + +Y ++S RTH G Y
Sbjct: 24175 GEAAQLSCQIVGRPLPDIKWYRFGKELIQ---SRKYKMSSDGRTHTLTVMTEEQEDEGVY 24231
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASF--PQPQVTW 147
CI N +G + + +++ + F G + +G + P P +TW
Sbjct: 24232 TCIATNEVGEV-ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTW 24290
Query: 148 FRDGRKIPPSSRIAITLENTLVILSTVAPD------AGRYYVQAVNDKNGDNKTSQPITL 201
F G+K+ +S IT+ENT V + AG+Y VQ N + L
Sbjct: 24291 FH-GQKLLQNSE-NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG-----TVDAIL 24343
Query: 202 TVENVGGPADPIAPTIIIPP-KNTSVVA-------GTSEVTLECVANARPLIKLHIIWKK 253
VE P P P +I KN++V++ G S +T V K W+
Sbjct: 24344 DVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEA--KEGAEWQ- 24400
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE 313
L+S IS R+ N T +AGYY + + + + + + +++ P ++
Sbjct: 24401 ---LVSSAISVTTCRIV--NLT-ENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP--FEK 24452
Query: 314 PERHITAEMEKVVDIPCQAKGVPPPSI------TWYKDAAVVEVEKLTRF--RQRNDGGL 365
P + V C PP S +Y + + K + +
Sbjct: 24453 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 24512
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLA-------VTSIAPNITRGPLDSTVIDGMS 418
+ L+ F+ N GE + S V AP+ + V +
Sbjct: 24513 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 24572
Query: 419 VVLACETSGAPRPAITW-QKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTC 475
L C+ +G P+P + W ++G+ I+A G R + G L+I+ DA Y
Sbjct: 24573 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY--RIQEFKGGYHQLIIASVTDDDATVYQV 24630
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSV-----IKGTQASMVCGVTHDPRVTIRYI 530
ATN G +A L V +I P + + ++G S+ + P I
Sbjct: 24631 RATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVIT-- 24688
Query: 531 WEKDGATLGTESHPRIRLDRNGSLHI--SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
W+K + H ++ + R+ + + + D G Y + G D ++ L V
Sbjct: 24689 WQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVAD 24748
Query: 589 LPHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKA 647
+P P +S V R ++NLTWT+P DG S + YI+E A + + +
Sbjct: 24749 VPDPPRG--VKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RE 24804
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 692
T TV L SYQFR+ A N G + S+ +E E+ A
Sbjct: 24805 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 24849
Score = 90.5 bits (223), Expect = 2e-17
Identities = 155/724 (21%), Positives = 278/724 (38%), Gaps = 106/724 (14%)
Query: 311 VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG---GLQI 367
+++ + +T ++ + + CQ G P P I WY+ E+ + +++ +DG L +
Sbjct: 24163 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGK--ELIQSRKYKMSSDGRTHTLTV 24220
Query: 368 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS- 426
+D G++ C A N GEV+TS+ L + + PL + L
Sbjct: 24221 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24280
Query: 427 -GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE 485
G P PA+TW G+++L + T + ++ + + AG Y +N G +
Sbjct: 24281 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVD 24340
Query: 486 ASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTI-RYIWEKDGATLGTESH 543
A D+ + + + T P ++++K + D I Y+ EK A G E
Sbjct: 24341 AILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE-- 24398
Query: 544 PRIRLDRNGSLHISQTWSGDIGTYTCRV------------ISAGGNDSRSAHLRVRQL-- 589
Q S I TCR+ +SA S L V +
Sbjct: 24399 -------------WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 24445
Query: 590 -------PHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
P AP P T++ V + + + W P DG + + Y LE E + +
Sbjct: 24446 IKSPFEKPGAPGKP--TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVT 24503
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP------Q 695
+ + + T +VK L+ Y+FR+ N G+ ++S+ +E ++ + P P +
Sbjct: 24504 TEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELR 24563
Query: 696 NVIASGRTNQSIMIQWQPPPESHQNGILKGYI---------IRYCLAGLPVGYQ---FKN 743
N+ ++N +++ + H I+K Y ++Y + GY +
Sbjct: 24564 NLNVRYQSNATLVCK----VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIAS 24619
Query: 744 ITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEAT 803
+TD D + TN V+ S + V + TL+G+ G VHA
Sbjct: 24620 VTDDDATVYQVRA----TNQGGSVSGTASLEVEVPAKIHLPKTLEGM-----GAVHALRG 24670
Query: 804 NSTTIRFTWNA-PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS--- 859
+I+ ++ P P +I W+ Q+ ++ ++Q + F S
Sbjct: 24671 EVVSIKIPFSGKPDP-----------VITWQKGQD----LIDNNGHYQVIVTRSFTSLVF 24715
Query: 860 --GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
G+++ F V+C + T +L DVP P + S++ S+ ++W E
Sbjct: 24716 PNGVERKDAGF-YVVCAKNRFGIDQKTVEL--DVADVPDPPRGVKVSDVSRDSVNLTWTE 24772
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P G +T Y + E+ T R Y V L T+Y V A G
Sbjct: 24773 PASDGGSKITNYIV--EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGL 24830
Query: 977 GQVS 980
+ S
Sbjct: 24831 SKPS 24834
Score = 83.6 bits (205), Expect = 2e-15
Identities = 113/486 (23%), Positives = 191/486 (39%), Gaps = 71/486 (14%)
Query: 120 KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAP 176
K +V+ GE A S+ V W+ G+K+ PS ++ E +TL +
Sbjct: 5831 KDVTVTAGETATFDCE--LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 5888
Query: 177 DAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
DAG + A + K N L V+ P P V + LE
Sbjct: 5889 DAGEVQLTAKDFKTHAN-------LFVKE--------PPVEFTKPLEDQTVEEGATAVLE 5933
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-----ISDHN-RRLTIPNPTGSDAGYYECEAVLRS 290
C + + W K+G + ++D R+L I + T D Y C+A
Sbjct: 5934 CEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK 5990
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVE 350
+S L+V+ P P + +++ C+ + W+KD A E
Sbjct: 5991 TS-------CNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVKWFKDGA--E 6040
Query: 351 VEKLTRFRQRNDGGLQI---SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRG 407
++K ++ + G ++I + + DD + C R A +TS L V T+
Sbjct: 6041 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLEEEAVFTKN 6096
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKG-ERILASGSVQLPRFTPLESGSLLISPTH 466
+ V + ++ L CE S P + W KG E I+ +G ++ T L+I H
Sbjct: 6097 LANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEI--LTEGRKRILVIQNAH 6153
Query: 467 ISDAGTYTCLATNSR-----GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
+ DAG Y C +SR V E +A+ + PQ+ +++G +A VC ++
Sbjct: 6154 LEDAGNYNCRLPSSRTDGKVKVHELAAEFI--------SKPQNLEILEGEKAEFVCSISK 6205
Query: 522 DPRVTIRYIWEKDGATLGT-ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
+ + W++D TL + + + I + L + D+GTY V G
Sbjct: 6206 E---SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARA 6258
Query: 581 SAHLRV 586
+AHL V
Sbjct: 6259 AAHLTV 6264
Score = 77.4 bits (189), Expect = 1e-13
Identities = 101/443 (22%), Positives = 159/443 (35%), Gaps = 77/443 (17%)
Query: 118 GEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTV 174
G K+ +V GE+ + I+ +P P VTW+R+ +I S IT ++ L+I
Sbjct: 902 GLKNVTVIEGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAF 960
Query: 175 APDAGRYYVQAVNDKNGDNKT-------------------------------SQPITLT- 202
A D+GR+ AVN+ + + S+ + +T
Sbjct: 961 AEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1020
Query: 203 ---VENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
E GP +P AP I P +V G S V C P K H+ WKK GV L+
Sbjct: 1021 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS-VVFGCQVGGNP--KPHVYWKKSGVPLT 1077
Query: 260 GGIS---DHNR-----RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQF- 310
G +N+ +L I DAG Y V+R+ + A S+LE +
Sbjct: 1078 TGYRYKVSYNKQTGECKLVISMTFADDAGEY--TIVVRNKHGET---SASASLLEEADYE 1132
Query: 311 -VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISG 369
+ + ++ + + + + G P + + E E+ ++ + +
Sbjct: 1133 LLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRT 1192
Query: 370 LVPDDTGMFQCFARNAAGEVQ---------------TSTYLAVTSIAPNITRGPLDS--- 411
V D F E++ +AV DS
Sbjct: 1193 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1252
Query: 412 --TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
+++GM V C+ SG P P I W K + + G F SL I D
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 470 AGTYTCLATNSRGVDEASADLVV 492
G YT A+N +G S L V
Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYV 1335
Score = 77.0 bits (188), Expect = 2e-13
Identities = 71/269 (26%), Positives = 105/269 (39%), Gaps = 58/269 (21%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-- 364
PP V + E E V + C G P P++TWY++ ++E F+ G
Sbjct: 896 PPTLVSGLKNVTVIEGESVT-LECHISGYPSPTVTWYRED--YQIESSIDFQITFQSGIA 952
Query: 365 -LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-------------------------- 397
L I +D+G F C A N AG V TS YLAV
Sbjct: 953 RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1012
Query: 398 --------TSI-----------APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKG 438
TS+ AP P+ +++G SVV C+ G P+P + W+K
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072
Query: 439 ERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWART 496
L +G + ++G L+IS T DAG YT + N G ASA L+ A
Sbjct: 1073 GVPLTTGYRYKVSYNK-QTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Query: 497 RITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ Q + + + + V +P+V
Sbjct: 1132 ELLMKSQQEMLYQ----TQVTAFVQEPKV 1156
Score = 69.3 bits (168), Expect = 4e-11
Identities = 134/549 (24%), Positives = 214/549 (38%), Gaps = 78/549 (14%)
Query: 897 PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS-WEEYNRTNTRVTHYLPNVTLEYR 954
P G + +L S +SW+ P + G +T Y + E ++ +VT R
Sbjct: 24354 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTT-CR 24412
Query: 955 VTGLTALTTYTIEVAAMTSKGQG---QVSASTISSGVPPELPGPPTNLGISNIGPRSVTL 1011
+ LT Y V+A + G +VS+ I P E PG P I+ + S +
Sbjct: 24413 IVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS-PFEKPGAPGKPTITAVTKDSCVV 24471
Query: 1012 QFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
++P DG I + +E + + +W+ + + E V +L Y FR
Sbjct: 24472 AWKPPASDGGAKIRNYYLEKREK---KQNKWISV--TTEEIRETVFSVKNLIEGLEYEFR 24526
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAP------ANVSLRTASETSLWLRWM--PLPE 1122
++ N+ G S S+ S I P AP N+++R S +L + P P
Sbjct: 24527 VKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 24586
Query: 1123 ME-YNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAI 1181
++ Y E + +KY + G ++ + D T+ QV+A N
Sbjct: 24587 VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATV----------YQVRATNQG 24636
Query: 1182 GS--GPWSQTVVGRTRESVPSS--GPTNVSALATTSSSMLVRWSEVPEA----------- 1226
GS G S V + +P + G V AL S+ + +S P+
Sbjct: 24637 GSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLI 24696
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
D NG Y+V+ + LV N + G YV V A R G
Sbjct: 24697 DNNG---HYQVIVTRSFTS------LVFPNG---VERKDAGFYV-----VCAKNRFGIDQ 24739
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+ +E + DVP PP G+ +V SV L W PA+ G +IT+ + A
Sbjct: 24740 KT----VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG----SKITNYIVEKCAT 24791
Query: 1347 TATVEVLAPSARQ--YTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPS 1404
TA + AR+ YT L ++ Y FR+ A+ + G + +E T K D+ +
Sbjct: 24792 TAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK----T 24847
Query: 1405 RPMVQQEDV 1413
R M E+V
Sbjct: 24848 RAMNYDEEV 24856
Score = 67.8 bits (164), Expect = 1e-10
Identities = 122/543 (22%), Positives = 201/543 (37%), Gaps = 95/543 (17%)
Query: 17 AARAQDDVSPYFKTEPVRTQVH------LEGNRLVLTCMAEGSWP-LEFKWLHNNRELT- 68
A +A + Y + + + H LE R + C E S P + +W+ +++EL
Sbjct: 2996 AGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFEC--EVSEPDITVQWMKDDQELQI 3053
Query: 69 -------KFSLEYRYMITSLDRTHAGFYRCIVRNRMGA--LLQRQTEVQVAYMGSFEEGE 119
K +R +I S + AG Y + + L +V++ + +
Sbjct: 3054 TDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSI------K 3107
Query: 120 KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKI--PPSSRIAITLE---NTLVILSTV 174
K V + AV+ + W++DG +I R +E + + I T
Sbjct: 3108 KEVQVIEKQRAVVEFE--VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3165
Query: 175 APDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVT 234
DAG Y A G N++S +TL V P P ++ + +V +G
Sbjct: 3166 QSDAGEYTFVA-----GRNRSS--VTLYVNA------PEPPQVLQELQPVTVQSG-KPAR 3211
Query: 235 LECVANARPLIKLHIIWKKDGVLLSGGIS------DHNRRLTIPNPTGSDAGYYECEA-- 286
V + RP K I W K+ LLS G L + DA Y CEA
Sbjct: 3212 FCAVISGRPQPK--ISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKN 3269
Query: 287 --------VLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPP 338
S VP VV + PP + + +T+E + C+ G
Sbjct: 3270 DYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPA-RFQCRVSGTDL- 3327
Query: 339 SITWYKDAAVVEVEKLTRFRQRNDG-GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
++WY ++ + R Q D L+I+ P+D G + A NA G+V ++ L++
Sbjct: 3328 KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Query: 398 ----------------TSIAPNITRGPLDS-----------TVIDGMSVVLACETSGAPR 430
S++ + + PL V +G +V SG P+
Sbjct: 3388 EGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPK 3447
Query: 431 PAITWQKGERILASGSVQLPRFTPLESGSL-LISPTHISDAGTYTCLATNSRGVDEASAD 489
P I W ++++ + F +L LI + AG Y+C A NS G +A
Sbjct: 3448 PEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAAT 3507
Query: 490 LVV 492
L V
Sbjct: 3508 LTV 3510
Score = 67.8 bits (164), Expect = 1e-10
Identities = 85/414 (20%), Positives = 173/414 (41%), Gaps = 46/414 (11%)
Query: 16 RAARAQDDVSPYFKTEPVRTQVHL-EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY 74
+ ++A ++V + + + TQ+ + EG RLVL G+ + KW+ N ELT S EY
Sbjct: 26655 KTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA--TDVKWVLNGVELTN-SEEY 26711
Query: 75 RYMITSLDRT---------HAGFYRCIVRNRMGALLQRQTEV----QVAYMGSFEEGEKH 121
RY ++ D+T G CI + + G +++ Q ++ +++ +F +
Sbjct: 26712 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEG-IVKCQYDLTLSKELSDAPAFISQPRS 26770
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDA 178
Q+++ G+ + I+ P P++ WF++ I SS ++I+ +L I + D+
Sbjct: 26771 QNINEGQNVLFTC-EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 26829
Query: 179 GRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECV 238
G+Y ++A N + + T+ + L + +P ++ +TS+ S +++
Sbjct: 26830 GKYTIKAKNFRGQCSATASLMVLPLVE-----EPSREVVLRTSGDTSLQGSFSSQSVQMS 26884
Query: 239 ANARPL-------IKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSS 291
A+ + + + +S + + + S G + S+
Sbjct: 26885 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESST 26944
Query: 292 S--VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S + + +RG PP+ P I+ + KV+ + C G P P +TW +
Sbjct: 26945 SKMLKAGIRGI------PPKIEALPS-DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 26997
Query: 350 EVEKLTRFRQRNDGGLQ---ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI 400
++ RF N L I + D G++ N G + + + SI
Sbjct: 26998 HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051
Score = 65.9 bits (159), Expect = 4e-10
Identities = 107/426 (25%), Positives = 171/426 (40%), Gaps = 45/426 (10%)
Query: 283 ECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEP-ERHITAEMEKVVDIPCQA--KGVPPPS 339
E EA + S P+ + LS+ +P P + H+T K + I + K P
Sbjct: 7889 ENEAGVGHPSEPTEI----LSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 7944
Query: 340 ITWYKDAAVVEVEKLTRFRQRNDGGLQIS---GLVPDDTGMFQCFARNAAG-----EVQT 391
I ++ + V EK R R L+ G+VPD + + A NA G E+
Sbjct: 7945 IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 8004
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLP 450
+ P I D VI+G + + P P ++W K G+ + AS + +
Sbjct: 8005 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 8064
Query: 451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKG 510
S L + + +DAG YT N G AS ++ V + P +D
Sbjct: 8065 N--DHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIG---LPGPCKDIKASDI 8119
Query: 511 TQASMVCGVTHDP------RVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDI 564
T++S C +T +P + Y+ E+ A G ++ + +G +S T I
Sbjct: 8120 TKSS--CKLTWEPPEFDGGTPILHYVLERREA--GRRTYIPVM---SGENKLSWTVKDLI 8172
Query: 565 --GTYTCRVISA----GGNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
G Y RV + GG + + Q P P P + A+ +TW P
Sbjct: 8173 PNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPL 8232
Query: 616 FDGNSPLIRYILE-MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S ++ YI+E +++ W + P T T KGL + YQFR+ A N G
Sbjct: 8233 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILT-YTAKGLEEGKEYQFRVRAENAAGIS 8291
Query: 675 QFSKDT 680
+ S+ T
Sbjct: 8292 EPSRAT 8297
Score = 65.9 bits (159), Expect = 4e-10
Identities = 75/363 (20%), Positives = 146/363 (40%), Gaps = 33/363 (9%)
Query: 251 WKKDGVLLSG------GISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSV 304
W +GV L+ G+S ++ LTI + D G C S + +V+ Y
Sbjct: 26698 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI----SKTKEGIVKCQYDLT 26753
Query: 305 L-----EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFR 358
L + P F+ +P E + V+ C+ G P P I W+K+ + + ++ R
Sbjct: 26754 LSKELSDAPAFISQPRSQNINEGQNVL-FTCEISGEPSPEIEWFKNNLPISISSNVSISR 26812
Query: 359 QRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL----DSTVI 414
RN L+I D+G + A+N G+ + L V + +R + T +
Sbjct: 26813 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 26872
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
G + + S + + A ++ AS ++ +F + + S+ + + +
Sbjct: 26873 QGSFSSQSVQMSASKQEA-SFSSFSSSSASSMTEM-KFASMSAQSMSSMQESFVEMSSSS 26930
Query: 475 CLATNSRGVDEASADLVVWARTRITKP-----PQDQSVIKGTQASMVCGVTHDPRVTIRY 529
+ ++ E+S ++ A R P P D S+ +G ++ C T +P T
Sbjct: 26931 FMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEP--TPEV 26988
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W G + ++ R ++ +L I D G YT + + G+DS + ++ +
Sbjct: 26989 TWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Query: 587 RQL 589
R +
Sbjct: 27049 RSI 27051
Score = 65.5 bits (158), Expect = 6e-10
Identities = 102/527 (19%), Positives = 182/527 (34%), Gaps = 106/527 (20%)
Query: 32 PVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNREL--------TKFSLEYRYMITSLDR 83
P++ V EG C G+ L+ W ++++ T+F Y+ I
Sbjct: 3304 PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3362
Query: 84 THAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQS-------------------- 123
G Y + N +G + + + FEE +
Sbjct: 3363 EDEGTYTFVASNAVGQV-SSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSF 3421
Query: 124 --------VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT-----LVI 170
V +GE A R++ P+P++ WF + + I P+ + E + ++I
Sbjct: 3422 IQPLSSLRVHNGETVRFHA-RVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLI 3480
Query: 171 LSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGT 230
+ + AG+Y +A N G+ + +T+T P AP I+ +
Sbjct: 3481 VDAYSEHAGQYSCKAANSA-GEATCAATLTVT---------PKAPESILHERIEQ----- 3525
Query: 231 SEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRS 290
E+ +E + + G+ +L+ N T E + S
Sbjct: 3526 -EIEMEMKEFSSSFLSAE----------EEGLHSAELQLSKINET--------LELLSES 3566
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVE 350
P+ P F+KE + M V + G+P P I W+ + ++
Sbjct: 3567 PVYPTKFDSEKEGT--GPIFIKEVS-NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLT 3623
Query: 351 VEKLTRFR-QRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS---------- 399
+F +D L I +D G + C A N G+ S YL + S
Sbjct: 3624 PSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTET 3683
Query: 400 ---IAPNITR--GPLDSTVI---------DGMSVVLACETSGAPRPAITWQKGERILASG 445
+A ++ + GP + G+ + G P P +TW K + L +
Sbjct: 3684 ESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTS 3743
Query: 446 SVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
P SG+ +++ D+G Y C A N G +A+L+V
Sbjct: 3744 VYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 64.7 bits (156), Expect = 9e-10
Identities = 118/468 (25%), Positives = 185/468 (39%), Gaps = 61/468 (13%)
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN----TLVILSTVAPD 177
Q+V G A R R+ P P+ W+++G KI S RI LVI A D
Sbjct: 2041 QTVGQGSDAHFRV-RVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAED 2099
Query: 178 AGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSE--VTL 235
+ V+A+N +TS L V+ I + VVA + T
Sbjct: 2100 SASIMVKAINIA---GETSSHAFLLVQ--------AKQLITFTQELQDVVAKEKDTMATF 2148
Query: 236 ECVANARPLIKLHIIWKKDGVLLSGG--ISDHNRR----LTIPNPTGSDAGYYECEAVLR 289
EC + P +K + W KDG+ + G H+ R L+I SDA Y C V
Sbjct: 2149 EC-ETSEPFVK--VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2205
Query: 290 ---SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY-KD 345
++ +V GA + ++ Q ++ PE + + E+E +V P +G WY D
Sbjct: 2206 ENVKTTAKLIVEGAVVEFVKELQDIEVPESY-SGELECIVS-PENIEG------KWYHND 2257
Query: 346 AAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ K T +R L + + +D G + +T+ L + I
Sbjct: 2258 VELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKLKMKPRPIAIL 2313
Query: 406 RGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
+G D V +G V L + S + + G+ + S V + +S LLI
Sbjct: 2314 QGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI--VIDKQSHMLLIEDM 2371
Query: 466 HISDAGTYTC------LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGV 519
DAG Y+ L+T+ R V S D++ P +D +VI+GT+A + C V
Sbjct: 2372 TKEDAGNYSFTIPALGLSTSGR-VSVYSVDVIT--------PLKDVNVIEGTKAVLECKV 2422
Query: 520 THDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
+ P VT + D + I L I++T + D G Y
Sbjct: 2423 S-VPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2469
Score = 64.3 bits (155), Expect = 1e-09
Identities = 86/335 (25%), Positives = 128/335 (38%), Gaps = 34/335 (10%)
Query: 268 RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVD 327
RL IP+ SDAG Y A S+ V G + + + +K+ E + + VV+
Sbjct: 3067 RLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRI----RSIKK-EVQVIEKQRAVVE 3121
Query: 328 IPCQAKGVPPPSITWYKDAAVVEVEKLTRFR---QRNDGGLQISGLVPDDTGMFQCFARN 384
V WYKD + + R + +R + IS D G +
Sbjct: 3122 FEVNEDDV---DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF---- 3174
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLACETSGAPRPAITWQKGERILA 443
AG ++S L V + P L TV G SG P+P I+W K E++L+
Sbjct: 3175 VAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLS 3234
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA--------- 494
+G + + +LL+ DA YTC A N GV SA L V
Sbjct: 3235 TG-FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Query: 495 ----RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW-EKDGATLGTESHPRIRLD 549
I P QD +G A C V+ ++ W KD + + +
Sbjct: 3294 MPVYPPAIITPLQDTVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
L I++ + D GTYT +A G S +A+L
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 64.3 bits (155), Expect = 1e-09
Identities = 103/471 (21%), Positives = 164/471 (34%), Gaps = 106/471 (22%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQ 197
P P VTW R G+ + S+R +T ++T I S A D G Y V +N + K
Sbjct: 26216 PVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVV---ENSEGKQEA 26272
Query: 198 PITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVL 257
TLT++ A + PP+ V + P +K K
Sbjct: 26273 EFTLTIQK----ARVTEKAVTSPPR---------------VKSPEPRVKSPEAVKSP--- 26310
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA-YLSVLEPPQFVKEPER 316
+R+ P P+ +AV + + P+ +L V PP+ + +
Sbjct: 26311 ---------KRVKSPEPSHP-------KAVSPTETKPTPTEKVQHLPVSAPPKITQFLKA 26354
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQISGLVPDD 374
+ E+ K+ + ++ + +TWYKD ++ +F DG L+I+ L D
Sbjct: 26355 EASKEIAKLTCV-VESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESD 26413
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G + CE SG
Sbjct: 26414 QGEY-------------------------------------------VCEISG------- 26423
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 494
+G + F + IS T SD T T E A + +
Sbjct: 26424 --EGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT---EPKAPEPISS 26478
Query: 495 RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS- 553
+ I QD +V + A T +PR T IW KDG + ++ D+ G
Sbjct: 26479 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTA--IWTKDGKAITQGGKYKLSEDKGGFF 26536
Query: 554 LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVE 604
L I +T + D G YTC V ++ G+ S S L ++ + V+T T E
Sbjct: 26537 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 26587
Score = 62.4 bits (150), Expect = 5e-09
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 8/165 (4%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQ 390
G P P ++W++D V+ L + G L I + ++G + A N +G+
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQAT 90
Query: 391 TSTYLAVTS--IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSV 447
++ L V + PN + TV G V L +G P P + + + G I +S
Sbjct: 91 STAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDF 150
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
Q+ + L S LLI+ + D+GTY+ ATNS G ++A+L+V
Sbjct: 151 QISQEGDLYS--LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 62.0 bits (149), Expect = 6e-09
Identities = 51/212 (24%), Positives = 104/212 (49%), Gaps = 13/212 (6%)
Query: 397 VTSIAPNITRGPLDSTVI-DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPL 455
+T+ AP T+ PL S V+ +G + SG P P ++W + +++++ ++ + +
Sbjct: 1 MTTQAPTFTQ-PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS 59
Query: 456 ESGSLLISPTHI-SDAGTYTCLATNSRGVDEASADLVVWART---RITKPPQDQSVIKGT 511
+ + L P +++G Y+ ATN G ++A+L+V A T + Q +V +G+
Sbjct: 60 DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGS 119
Query: 512 QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH---ISQTWSGDIGTYT 568
Q + VT P +++ +DGA + +S ++ + G L+ I++ + D GTY+
Sbjct: 120 QVRLQVRVTGIPTPVVKFY--RDGAEI--QSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 569 CRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
++ G + +A L V+ P T+
Sbjct: 176 VNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Score = 62.0 bits (149), Expect = 6e-09
Identities = 50/193 (25%), Positives = 85/193 (44%), Gaps = 13/193 (6%)
Query: 214 APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG--------ISDH 265
APT P ++ V+ G S T E + P+ + + W +DG ++S SD
Sbjct: 5 APTFTQPLQSVVVLEG-STATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDG 61
Query: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
+LTIP T +++G Y +A S S + PP FV+ + +T
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-SMTVRQGSQ 120
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARN 384
V + + G+P P + +Y+D A ++ + Q D L I+ P+D+G + A N
Sbjct: 121 VRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 385 AAGEVQTSTYLAV 397
+ G ++ L V
Sbjct: 181 SVGRATSTAELLV 193
Score = 61.6 bits (148), Expect = 8e-09
Identities = 73/294 (24%), Positives = 108/294 (36%), Gaps = 64/294 (21%)
Query: 343 YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA- 401
YK A VEV+K + G+ I+G + F+ A +T+ A I
Sbjct: 844 YKSEAGVEVKK--------EVGVSITGTTVREE-RFEVLHGREAKVTETARVPAPVEIPV 894
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P + G + TVI+G SV L C SG P P +TW + + + S S+
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIES-SIDFQITFQSGIAR 953
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADL----------------------------- 490
L+I D+G +TC A N G S L
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013
Query: 491 --VVWARTRITK---------------PPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
VV T +T+ P Q +++G C V +P+ + W+K
Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV--YWKK 1071
Query: 534 DGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
G L T ++ ++ L IS T++ D G YT V + G S SA L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 58.9 bits (141), Expect = 5e-08
Identities = 73/277 (26%), Positives = 111/277 (40%), Gaps = 21/277 (7%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSI--TWYKDAAVVEVEKLTRF-RQRNDG 363
P +FVKE + I E E V V P + TW KD + + RF D
Sbjct: 4742 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 4801
Query: 364 GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLA 422
L I + D G + C R E ++ L V + + + TV+ G + L+
Sbjct: 4802 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLS 4861
Query: 423 CETSGAPRPAITWQKGERILASGSVQLP-RFTPLESG---SLLISPTHISDAGTYTCLAT 478
CE + + W+K +I+ V+ P R P G +L I+ +DAGTYT
Sbjct: 4862 CELN--KERDVVWRKDGKIV----VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 4915
Query: 479 NSRGVDEASADLVVWA-RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
N+ ++ +S VV R + KP +DQ V A C + D T W K
Sbjct: 4916 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKD---TPNIKWFKGYDE 4972
Query: 538 LGTESHPRIRLDRNGS---LHISQTWSGDIGTYTCRV 571
+ E + + + R+G+ L I DI Y +
Sbjct: 4973 IPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 5009
Score = 58.5 bits (140), Expect = 7e-08
Identities = 119/615 (19%), Positives = 209/615 (33%), Gaps = 95/615 (15%)
Query: 22 DDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSL 81
+ +PYF T+PV Q +EG +V C G+ W + LT YRY ++
Sbjct: 1032 EPAAPYFITKPV-VQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTT---GYRYKVSYN 1087
Query: 82 DRT-------------HAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGE 128
+T AG Y +VRN+ G + ++ A + ++
Sbjct: 1088 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQV 1147
Query: 129 AAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVND 188
A ++ P++ V + + I + V++ T D +++ + +
Sbjct: 1148 TAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQ-EFHISSFEE 1206
Query: 189 KNGDNKTSQPITLTVENVG------------GPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
+ + I T+E + ++ + KN ++ G VT
Sbjct: 1207 RLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMG-VTFH 1265
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-------ISDHNRRLTIPNPTGSDAGYYECEAVLR 289
C + PL K I W KDG + G + D L IP D G Y A
Sbjct: 1266 CKMSGYPLPK--IAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA--- 1320
Query: 290 SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S ++G + C K P+ +
Sbjct: 1321 -----SNIKGNAI---------------------------CSGKLYVEPAAPLGAPTYIP 1348
Query: 350 EVEKLTRFRQRNDGGLQISGLVPDDTGMFQCF---ARNAAGEVQTSTYLAVTSIA----- 401
+E ++R R + + S + M AR + + L T +
Sbjct: 1349 TLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERL 1408
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P P+ ++G + + G P P W + + + + S
Sbjct: 1409 YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQS 1468
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQAS 514
L+I P SD+G +T +A N G S L V A KP ++ ++ +G++
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1528
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD---RNGSLHISQTWSGDIGTYTCRV 571
M T +P I +W K+ + +P+IR++ +L I T S D YT
Sbjct: 1529 MKVRATGNPNPDI--VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1586
Query: 572 ISAGGNDSRSAHLRV 586
I+ G D+ + V
Sbjct: 1587 INKAGRDTTRCKVNV 1601
Score = 58.5 bits (140), Expect = 7e-08
Identities = 63/252 (25%), Positives = 95/252 (37%), Gaps = 21/252 (8%)
Query: 262 ISDHNRRLTIPNPTGSDAGYYEC---------EAVLRSSSVPSVVRGAYLSVLEPPQFVK 312
+ D R + N G D+ Y E + R + R + +LE P
Sbjct: 25262 LDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFT 25321
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRNDGGLQ---IS 368
P + TA + + V P P +TWYK ++ + ++ +D GL I+
Sbjct: 25322 LPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTIN 25381
Query: 369 GLVPDDTGMFQCFARNAAGEVQTSTYLAVT--------SIAPNITRGPLDSTVIDGMSVV 420
+ DD + ARN GE L VT ++ P R ++ +G SV
Sbjct: 25382 SVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVC 25441
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
SG P P + W+K + L+ G L+ +L I T D G Y ATN+
Sbjct: 25442 FEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT 25501
Query: 481 RGVDEASADLVV 492
G A L V
Sbjct: 25502 AGSTSCQAHLQV 25513
Score = 57.8 bits (138), Expect = 1e-07
Identities = 84/361 (23%), Positives = 124/361 (34%), Gaps = 62/361 (17%)
Query: 279 AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPP 338
A C +RS SV + S+ P V H E V C+ +
Sbjct: 25168 AARISCGGAIRSQKGVSVAKVKVASIEIGP--VSGQIMHAVGEEGGHVKYVCKIENYDQS 25225
Query: 339 S-ITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTY 394
+ +TWY V ++E ++ + G L + + D G ++C N GE +
Sbjct: 25226 TQVTWY--FGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAE 25283
Query: 395 LAVTSIA---------------------------PNITRGPLDSTVIDGMSVVLACETSG 427
L V + P T + T G +V +
Sbjct: 25284 LFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITV 25343
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDE 485
P P +TW K + + G + G L I+ D YT +A N G D
Sbjct: 25344 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS 25403
Query: 486 ASADLVVWARTRITKPPQDQSV---IKGTQASMVCG----------VTHDPRVTIRYIWE 532
A L V + PP D ++ K A+ C V+ P T++ WE
Sbjct: 25404 CKAKLTV----TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WE 25457
Query: 533 KDGATLGTESHPRIRLDRNG----SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
KDG L P I + G +LHI T D G Y + G+ S AHL+V +
Sbjct: 25458 KDGQPLSLG--PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVER 25515
Query: 589 L 589
L
Sbjct: 25516 L 25516
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Query: 388 EVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSV 447
E +++T T++A I P TV +G S +C+T G P P +TW + ++L++ +
Sbjct: 26175 EEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSAR 26234
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW----ARTRITKPPQ 503
T +S + IS SD G Y+ + NS G EA L + +T PP+
Sbjct: 26235 HQVTTTKYKS-TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPR 26293
Query: 504 DQS 506
+S
Sbjct: 26294 VKS 26296
Score = 55.8 bits (133), Expect = 4e-07
Identities = 90/391 (23%), Positives = 145/391 (37%), Gaps = 54/391 (13%)
Query: 56 LEFKWLHNN--RELTKF--SLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY 111
L+ WL R TK +L++R +L + R G ++ Q V VA
Sbjct: 25128 LQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAK 25187
Query: 112 M--GSFEEGEKHQSVSH--GEAA--VIRAPRIASFPQP-QVTWFRDGRKIPPSSRIAITL 164
+ S E G + H GE V +I ++ Q QVTW+ R++ S + IT
Sbjct: 25188 VKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25247
Query: 165 ENTLVIL---STVAPDAGRYYVQAVNDKNGDNKTSQPIT------------LTVENVGGP 209
E+ + IL D G Y + VND D+ ++ T++ +
Sbjct: 25248 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25307
Query: 210 ADPI-----APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISD 264
D + P +P N + G V P + H+ W K G + G +D
Sbjct: 25308 TDTMRLLERPPEFTLPLYNKTAYVG-ENVRFGVTITVHP--EPHVTWYKSGQKIKPGDND 25364
Query: 265 HN---------RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP---QFVK 312
+LTI + T D Y V R+ + L PP ++
Sbjct: 25365 KKYTFESDKGLYQLTINSVTTDDDAEY--TVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25422
Query: 313 EPERHITAEME----KVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRND-GGLQ 366
+ + A E + V + G+PPP++ W KD + + + + D L
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
I +P+DTG ++ A N AG +L V
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25513
Score = 55.5 bits (132), Expect = 6e-07
Identities = 62/224 (27%), Positives = 93/224 (41%), Gaps = 25/224 (11%)
Query: 1721 QAAPSAPSS-VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVS-KIVTVD 1777
Q P P+ + L S +SW+ P G + Y V E C +G ++V+
Sbjct: 24348 QDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNY--VVEKCEAKEGAEWQLVSSA 24405
Query: 1778 VKGNSPLWLKVKDLAEGVTYRFRIRAK-TFTYGPEIEAN---VTTGPGE--GAPGPPGVP 1831
+ S ++ +L E Y FR+ A+ TF +E + + P E GAPG P +
Sbjct: 24406 I---SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24462
Query: 1832 IIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILK 1891
+ + S +A + D G I Y +E R + W I +E+ FS+ L
Sbjct: 24463 AVTKDSCVVAWKPPASDGG-AKIRNYYLEKREKKQNKW---ISVTTEEIRETVFSVKNLI 24518
Query: 1892 PGVSYDFRVIAVNDYG------FGTPSSPSQSVPAQKANPFYEE 1929
G+ Y+FRV N G P +P VP Q A F EE
Sbjct: 24519 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ-APHFKEE 24561
Score = 55.1 bits (131), Expect = 7e-07
Identities = 128/600 (21%), Positives = 208/600 (34%), Gaps = 102/600 (17%)
Query: 23 DVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---KFSLEYRYM-- 77
+ PYF T + + +E + + L C P+ KW + E+ K+S++ +
Sbjct: 5288 EADPYF-TVKLHDKTAVEKDEITLKCEVSKDVPV--KWFKDGEEIVPSPKYSIKADGLRR 5344
Query: 78 ---ITSLDRTHAGFYRCIV---RNRMGALLQRQ----------TEVQVAYMGSFEEGEKH 121
I D G Y C + + ++ + EV V FE
Sbjct: 5345 ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSE 5404
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY 181
V HG+ + P AS P DG+K + L++ + G
Sbjct: 5405 PDV-HGQWKLKGQPLTAS---PDCEIIEDGKK------------HILILHNCQLGMTGEV 5448
Query: 182 YVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANA 241
QA N K+ N L V+ + P I I P + V E EC +
Sbjct: 5449 SFQAANAKSAAN-------LKVKEL--------PLIFITPLSDVKVFEKDEAKFECEVSR 5493
Query: 242 RPLIKLHIIWKKDGVLLSGG-----ISDHNRR-LTIPNPTGSDAGYYECEAVLRSSSVPS 295
P W K ++G I D + + I + D Y EA + +S
Sbjct: 5494 EPKT---FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKL 5550
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKL 354
++ G L L P + V E+ V + + + W+K D + +
Sbjct: 5551 IIEGIRLKFLTPLKDVTAKEKE-----SAVFTVELSHDNI---RVKWFKNDQRLHTTRSV 5602
Query: 355 TRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI 414
+ + + L DDT + A + E + L V P T D T +
Sbjct: 5603 SMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAK----LTVLEGDPYFTGKLQDYTGV 5658
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
+ V+L CE S A P ++ G+ I S + + + L++ SD G YT
Sbjct: 5659 EKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIK--ADGKKRMLILKKALKSDIGQYT 5716
Query: 475 CLATNSRGVDEASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
C G D+ S L + R ++ +P V++ A ++ D I W+
Sbjct: 5717 C----DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISED---DIHANWKL 5769
Query: 534 DGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG------NDSRSAHLRVR 587
G L P + G +H + + CR+ GG N SAHLRV+
Sbjct: 5770 KGEAL--LQTPDCEIKEEGKIH-------SLVLHNCRLDQTGGVDFQAANVKSSAHLRVK 5820
Score = 54.7 bits (130), Expect = 1e-06
Identities = 91/439 (20%), Positives = 152/439 (34%), Gaps = 53/439 (12%)
Query: 92 IVRNRMGALLQRQTEVQVAY--------MGSFEEGEKHQSVSHGEAAVIRAPRIASFPQP 143
I++ + LL+ E ++A F+ K+ + G +++ +P P
Sbjct: 1216 IIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHC-KMSGYPLP 1274
Query: 144 QVTWFRDGRKIPPSSRIAITL----ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPI 199
++ W++DG++I R + +L I + D G Y A N K + +
Sbjct: 1275 KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK-- 1332
Query: 200 TLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
L VE PA P+ IP TLE V+ R L + + + +S
Sbjct: 1333 -LYVE----PAAPLGAPTYIP-------------TLEPVSRIRSLSPRSV--SRSPIRMS 1372
Query: 260 GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHIT 319
R +P L + + R L P FV +P
Sbjct: 1373 PARMSPARM----SPARMSPARMSPGRRLEETDESQLER------LYKPVFVLKPVSFKC 1422
Query: 320 AEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGLVPDDTGM 377
E + + G P P W+ D + + + + DG L I P D+G
Sbjct: 1423 LEGQ-TARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGE 1481
Query: 378 FQCFARNAAGEVQTSTYLAVTSIA----PNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
+ A+N AG S L V ++ P + + +G + + +G P P I
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 434 TWQKGERILASGSVQLPRFTPLES-GSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
W K I+ R + +L I T D+ YT A N G D + V
Sbjct: 1542 VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Query: 493 WARTRITKPPQDQSVIKGT 511
+P + + +GT
Sbjct: 1602 EVEFAEPEPERKLIIPRGT 1620
Score = 53.5 bits (127), Expect = 2e-06
Identities = 85/398 (21%), Positives = 146/398 (36%), Gaps = 47/398 (11%)
Query: 221 PKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG-----ISDHNRRLTIPNPT 275
P V + ECV + ++IW K ++ I+D + + + N +
Sbjct: 5119 PLKDVTVPERRQARFECVLTR----EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 5174
Query: 276 G-SDAGYYECEAVLRSSSVPSVVRGAYLSVLEP--PQFVKEPERHITAEMEKVVDIPCQA 332
D G Y E + +S V G L + P Q VKE E C+
Sbjct: 5175 QFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGE---------TATFVCEL 5225
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARNAAGEVQT 391
+ W+K+ A + + L++ + DD + + E+ +
Sbjct: 5226 SH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----ELSS 5280
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPR 451
+ L V P T D T ++ + L CE S P ++ GE I+ S P+
Sbjct: 5281 TAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVKWFKDGEEIVPS-----PK 5334
Query: 452 FTPLESG---SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR-TRITKPPQDQSV 507
++ G L I + D G Y C G D+ A++ V AR ++ KP V
Sbjct: 5335 YSIKADGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARLIKVEKPLYGVEV 5390
Query: 508 IKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
G A ++ + W+ G L + P + +G HI + +G
Sbjct: 5391 FVGETAHFEIELSEP---DVHGQWKLKGQPL--TASPDCEIIEDGKKHILILHNCQLG-M 5444
Query: 568 TCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
T V N +A+L+V++LP P++ + E+
Sbjct: 5445 TGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEK 5482
Score = 53.1 bits (126), Expect = 3e-06
Identities = 97/442 (21%), Positives = 163/442 (36%), Gaps = 51/442 (11%)
Query: 145 VTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITL 201
V WF+DG++I PS I + L++ + D G+Y G +KTS + +
Sbjct: 5676 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC-----GTDKTSGKLDI 5730
Query: 202 TVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLL--- 258
+ + P + T +E++ + +H WK G L
Sbjct: 5731 EDREI----KLVRPLHSVEVMETETARFETEISED---------DIHANWKLKGEALLQT 5777
Query: 259 -SGGISDHNR--RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPE 315
I + + L + N G + +A SS V+ + +L P + V
Sbjct: 5778 PDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT--- 5834
Query: 316 RHITAEMEKVVDIPCQAKGVPPPSITWY-KDAAVVEVEKLTRFRQRNDGGLQISGLVPDD 374
+TA D + +P + WY K + +K+ + L + + +D
Sbjct: 5835 --VTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 5889
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G Q A+ + +T L V T+ D TV +G + VL CE S
Sbjct: 5890 AGEVQLTAK----DFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKW 5945
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADL-VVW 493
++ G IL S ++ + L+I D TYTC A + + S +L VV
Sbjct: 5946 FKNGTEILKSKKYEIVADGRVR--KLVIHDCTPEDIKTYTCDAKDFK----TSCNLNVVP 5999
Query: 494 ARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT-ESHPRIRLDRNG 552
+P D V + A C ++ R + W KDGA + + + I
Sbjct: 6000 PHVEFLRPLTDLQVREKEMARFECELS---RENAKVKWFKDGAEIKKGKKYDIISKGAVR 6056
Query: 553 SLHISQTWSGDIGTYTCRVISA 574
L I++ D Y+C V +A
Sbjct: 6057 ILVINKCLLDDEAEYSCEVRTA 6078
Score = 50.8 bits (120), Expect = 1e-05
Identities = 68/294 (23%), Positives = 106/294 (36%), Gaps = 43/294 (14%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTR--FRQRNDGGLQISGLVPDDTGMFQCFAR 383
V C+ G P P I WYKD ++ + + F Q L+I ++P+D G++ FA
Sbjct: 1262 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1321
Query: 384 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 443
N G S L V AP GAP T + RI +
Sbjct: 1322 NIKGNAICSGKLYVEPAAP-----------------------LGAPTYIPTLEPVSRIRS 1358
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP-- 501
+ R +P+ +SP +S A + R ++E + R+ KP
Sbjct: 1359 LSPRSVSR-SPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQL----ERLYKPVF 1413
Query: 502 ---PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG--SLHI 556
P ++G A V P W DG + + ++ + +G SL I
Sbjct: 1414 VLKPVSFKCLEGQTARFDLKVVGRPMP--ETFWFHDGQQIVNDYTHKVVIKEDGTQSLII 1471
Query: 557 SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINL 610
D G +T + G S S L V A EH V + + + +N+
Sbjct: 1472 VPATPSDSGEWTVVAQNRAGRSSISVILTV----EAVEHQVKPMFVEKLKNVNI 1521
Score = 50.4 bits (119), Expect = 2e-05
Identities = 104/471 (22%), Positives = 175/471 (37%), Gaps = 66/471 (14%)
Query: 113 GSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLV 169
G+ + Q+V+ + AV + P + W RDG+ +P ++ I + L+
Sbjct: 2574 GAISKPLTDQTVAESQEAVFECE--VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLI 2631
Query: 170 ILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAG 229
I +T D G Y + K L VE V I T+ KN +V
Sbjct: 2632 IAATKLDDIGEYTYKVATSKTS-------AKLKVEAV-----KIKKTL----KNLTVT-- 2673
Query: 230 TSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLR 289
++ + V P +K + W K+GV+L + N + I S G +
Sbjct: 2674 ETQDAVFTVELTHPNVK-GVQWIKNGVVL-----ESNEKYAI-----SVKGTIYSLRIKN 2722
Query: 290 SSSVPSVVRGAYLSVL--------EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSIT 341
+ V V G L L E + +K+P + +TA V P
Sbjct: 2723 CAIVDESVYGFRLGRLGASARLHVETVKIIKKP-KDVTALENATVAFEVSVSHDTVPVKW 2781
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
++K + +K +R L + + P D G + G+++ L V ++
Sbjct: 2782 FHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTA----VVGQLECKAKLFVETL- 2836
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+IT+ + V + + CE S P++ + G I S ++ L L+
Sbjct: 2837 -HITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLH--QLI 2893
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
I T D+ YT + N D+ SA L V P S++K A +T
Sbjct: 2894 IMNTSTEDSAEYTFVCGN----DQVSATLTV-------TPIMITSMLKDINAEEKDTITF 2942
Query: 522 DPRVT---IRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYT 568
+ V I Y W K+G + + ++R + SL+I GD YT
Sbjct: 2943 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYT 2993
Score = 50.1 bits (118), Expect = 2e-05
Identities = 48/156 (30%), Positives = 63/156 (40%), Gaps = 4/156 (2%)
Query: 340 ITWY-KDAAVVEVEKLTRFRQRNDGGLQISGLVPDD-TGMFQCFARNAAGEVQTSTYLAV 397
+ WY ++ V EK + +N L I + +D G + C A N +G+ TS L V
Sbjct: 4397 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4456
Query: 398 TS-IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLE 456
AP I R V G CE AP W K R + R +
Sbjct: 4457 VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4516
Query: 457 SGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
S SL I T + D G YTC A+N G +A L V
Sbjct: 4517 S-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/350 (24%), Positives = 134/350 (38%), Gaps = 39/350 (11%)
Query: 232 EVTLEC-VANARPLIKLHIIWKKDGVLLSGG------ISDHNRRLTIPNPTGSDAGYYEC 284
EV L+C ++ A +K W KDG + R L + SD G Y C
Sbjct: 5662 EVILQCEISKADAPVK----WFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC 5717
Query: 285 EAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV---DIPCQAKGVPPPSIT 341
+ +S + + ++ P V+ E TA E + DI K
Sbjct: 5718 DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETE-TARFETEISEDDIHANWK-------- 5768
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
K A+++ + L + D TG A N V++S +L V
Sbjct: 5769 -LKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAAN----VKSSAHLRVKPRV 5823
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+ R D TV G + CE S P + KG+++ S V +PR + + +L
Sbjct: 5824 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKV-VPR-SEGKVHTLT 5881
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVV-WARTRITKPPQDQSVIKGTQASMVCGVT 520
+ + DAG A + + A+L V TKP +DQ+V +G A + C V+
Sbjct: 5882 LRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS 5937
Query: 521 HDPRVTIRYIWEKDGA-TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTC 569
R + W K+G L ++ + + R L I DI TYTC
Sbjct: 5938 ---RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5984
Score = 48.1 bits (113), Expect = 9e-05
Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 1850 GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G +T Y++E R +D W + EV +F + L PG Y FRV AVN+YG G
Sbjct: 12354 GGSQVTHYIVEKREADRKTWST----VTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPG 12409
Query: 1910 TPSSPSQSVPA 1920
P+ + V A
Sbjct: 12410 VPTDVPKPVLA 12420
Score = 47.8 bits (112), Expect = 1e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 1364 GLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW- 1422
G++ + + + A+ R G + L V D P PP V+ DV SV L+W
Sbjct: 24718 GVERKDAGFYVVCAKNRFGIDQKTVELDVA----DVPDPPRG--VKVSDVSRDSVNLTWT 24771
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
EP SDG S + Y ++ + RW + + + V L TSY+FRV A N
Sbjct: 24772 EPASDGGSKITNYIVEKCATTAERWLRVGQA---RETRYTVINLFGKTSYQFRVIAENKF 24828
Query: 1483 GDSEFSEESESLTT 1496
G S+ SE SE T
Sbjct: 24829 GLSKPSEPSEPTIT 24842
Score = 47.0 bits (110), Expect = 2e-04
Identities = 66/318 (20%), Positives = 120/318 (37%), Gaps = 55/318 (17%)
Query: 30 TEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSL----------EYRYMIT 79
T+P+++ V LEG+ G E W + + ++ +L + I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 80 SLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP-RIA 138
++ + ++G Y N G + A ++ QS++ + + +R R+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 139 SFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
P P V ++RDG +I S I+ E +L+I D+G Y V A N T
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATST 188
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVT----------LECVANARPLI 245
++ + E V P K T + T++++ +E +AR +
Sbjct: 189 AELLVQGEEEV-------------PAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIA 235
Query: 246 KLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVL 305
+ ++ DG +G H IP S RS + PS+ A L+
Sbjct: 236 TVEMV--IDGA--AGQQLPHKTPPRIPPKPKS-----------RSPTPPSIAAKAQLARQ 280
Query: 306 EPPQFVK---EPERHITA 320
+ P ++ P RH+ A
Sbjct: 281 QSPSPIRHSPSPVRHVRA 298
Score = 46.2 bits (108), Expect = 3e-04
Identities = 64/304 (21%), Positives = 114/304 (37%), Gaps = 32/304 (10%)
Query: 304 VLEPPQFVKEPERHITAEMEKVVDIPC--------QAKGVPPPSITWYKDAAVVEVEKLT 355
VL F + IT M +PC + P + WY + VE+++ +
Sbjct: 25990 VLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQSKPTAEVKWYHNG--VELQESS 26046
Query: 356 RFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-----TSIAPNITRG 407
+ N G L+I DD+G ++ N GE L V T+ A
Sbjct: 26047 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDE 26106
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHI 467
+ +V ++ A S +++K + AS SV+ + E+ L S H
Sbjct: 26107 EVPRSVFPELTRTEAYAVS-------SFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 26159
Query: 468 SDAGTYTCLATNSRGVDEASA--DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ A + A + ++E S + RI P+ +V +G A C +P
Sbjct: 26160 ASAEMKSA-ALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVP 26218
Query: 526 TIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
T+ W + G L T + ++ + + IS + D G Y+ V ++ G L
Sbjct: 26219 TV--TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 26276
Query: 585 RVRQ 588
+++
Sbjct: 26277 TIQK 26280
Score = 45.4 bits (106), Expect = 6e-04
Identities = 52/240 (21%), Positives = 89/240 (37%), Gaps = 51/240 (21%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITL---ENTLVILSTVAPDAGR 180
+S G+ A + + P+P++ WF +G + PS+ +++L+IL T D G
Sbjct: 3593 ISMGDVATLSVT-VIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGE 3651
Query: 181 YYVQAVND-----------------KNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKN 223
Y A ND + D +T + ++E +GGP P + P +
Sbjct: 3652 YTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRC 3711
Query: 224 TSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGI-------SDHNRRLTIPNPTG 276
+ E T+ V P + W K+ L + + + + +P
Sbjct: 3712 AQGLPAIFEYTV--VGEPAPT----VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQR 3765
Query: 277 SDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVP 336
D+G Y C+A + + A L VL E + D PC+AK P
Sbjct: 3766 EDSGLYICKA---ENMLGESTCAAELLVL--------------LEDTDMTDTPCKAKSTP 3808
Score = 44.3 bits (103), Expect = 0.001
Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 459 SLLISPTHISD-AGTYTCLATNSRGVDEASADLVVWARTR--ITKPPQDQSVIKGTQASM 515
+L+I + D G Y C A N G SA L V R I + + V G A
Sbjct: 4422 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKF 4481
Query: 516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISA 574
C + P V R+ W K G + IR + SL I +T D G YTC+ +
Sbjct: 4482 TCEIQSAPNV--RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4539
Query: 575 GGNDSRSAHLRV 586
G+ S +A L V
Sbjct: 4540 YGSVSCTATLTV 4551
Score = 42.7 bits (99), Expect = 0.004
Identities = 102/543 (18%), Positives = 186/543 (34%), Gaps = 78/543 (14%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDN 193
+ S P +V W+ +G ++ SS+I T + TL IL D+G Y N K
Sbjct: 26025 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG--- 26081
Query: 194 KTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKK 253
+ S TL V GG A SV + V++ + K
Sbjct: 26082 EASDYATLDV--TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK---------KT 26130
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSD----AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQ 309
+ S + + ++T + S A A L S+ + +
Sbjct: 26131 SEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR 26190
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVE---KLTRFRQRNDGGLQ 366
+ +P R +T + C G P P++TW + V+ ++T + ++ +
Sbjct: 26191 ILTKP-RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKST--FE 26247
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS 426
IS + D G + N+ G+ + L + +T V +
Sbjct: 26248 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKA--RVTE-----------KAVTSPPRV 26294
Query: 427 GAPRPAITWQKGERILASGSVQLPRF--TPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
+P P R+ + +V+ P+ +P S +SPT T
Sbjct: 26295 KSPEP--------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPT------------ 26334
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHP 544
E L V A +IT+ + ++ A + C V W KDG L H
Sbjct: 26335 EKVQHLPVSAPPKITQFLKAEA--SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHF 26392
Query: 545 RIRLDRNGS--LHISQTWSGDIGTYTCRVISAGGNDS----------RSAHLRVRQLPHA 592
+ +G+ L I+ D G Y C + GG +S H +V ++
Sbjct: 26393 QFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISET 26452
Query: 593 PEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE--MSENNAPWTVLLASVDPKATSV 650
+ T + R +P ++ + + +S ++ + A+ +P+ T++
Sbjct: 26453 KKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAI 26512
Query: 651 TVK 653
K
Sbjct: 26513 WTK 26515
Score = 40.8 bits (94), Expect = 0.015
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 11/145 (7%)
Query: 77 MITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE-----KHQSVSHGEAAV 131
+IT+L + +R + N G R V + E + SV G+
Sbjct: 16817 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16876
Query: 132 IRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVND 188
I P I+ P+P +TW +DG + ++RI +T TL I T D G+Y + N
Sbjct: 16877 IEVP-ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV 16935
Query: 189 KNGDNKTSQPITLTVENVGGPADPI 213
KT+ +T++ P P+
Sbjct: 16936 VG--QKTASIEIVTLDKPDPPKGPV 16958
Score = 40.4 bits (93), Expect = 0.019
Identities = 47/198 (23%), Positives = 74/198 (37%), Gaps = 30/198 (15%)
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
G L+ G P+P I W +L + S + SL+I T + D G YTC
Sbjct: 3596 GDVATLSVTVIGIPKPKIQWFFNG-VLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTC 3654
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVI-------------------------KG 510
+A+N G SA L + ++ K + +S + +G
Sbjct: 3655 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3714
Query: 511 TQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS--LHISQTWSGDIGTYT 568
A V +P T+ W K+ L T + I + NGS ++ D G Y
Sbjct: 3715 LPAIFEYTVVGEPAPTV--TWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYI 3772
Query: 569 CRVISAGGNDSRSAHLRV 586
C+ + G + +A L V
Sbjct: 3773 CKAENMLGESTCAAELLV 3790
Score = 40.4 bits (93), Expect = 0.019
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAG 179
++ G+ V+ A I P P+ +W + G+ I PS IT T L I DAG
Sbjct: 14017 TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAG 14076
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
Y + A N + + +TV +V GP P+ + + K T
Sbjct: 14077 EYTITATNP---FGTKVEHVKVTVLDVPGPPGPVEISNVSAEKAT 14118
Score = 40.0 bits (92), Expect = 0.025
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 20/175 (11%)
Query: 416 GMSVVLACETSGAPRPAIT-WQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAG 471
G S + C S P AIT W K S + P+ + G L I +SDAG
Sbjct: 4761 GSSAIFECLVS--PSTAITTWMKD----GSNIRESPKHRFIADGKDRKLHIIDVQLSDAG 4814
Query: 472 TYTCLATNSRGVDEASADLVV-WARTRITKPPQDQ-SVIKGTQASMVCGVTHDPRVTIRY 529
YTC+ ++A LVV R K +++ +V+KG + C + + V
Sbjct: 4815 EYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV---- 4870
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRS 581
+W KDG + E RI G +L I+ D GTYT V +A + S
Sbjct: 4871 VWRKDGKIV-VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSS 4924
Score = 39.3 bits (90), Expect = 0.043
Identities = 54/219 (24%), Positives = 84/219 (38%), Gaps = 29/219 (13%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---------KFSLEYRY 76
P F +PV + LEG G E W H+ +++ K
Sbjct: 1411 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 77 MITSLDRTHAGFYRCIVRNRMGA------LLQRQTEVQVAYMGSFEEGEKHQSVSHGEAA 130
+I + +G + + +NR G L E QV M F E K+ ++ G
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPM--FVEKLKNVNIKEGSRL 1527
Query: 131 VIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT-----LVILSTVAPDAGRYYVQA 185
++ R P P + W ++ I P I +E T L I STV+ D+ Y A
Sbjct: 1528 EMKV-RATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1586
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
+N K G + T + + VE A+P +I P+ T
Sbjct: 1587 IN-KAGRDTTRCKVNVEVEF----AEPEPERKLIIPRGT 1620
Score = 38.9 bits (89), Expect = 0.056
Identities = 39/150 (26%), Positives = 59/150 (39%), Gaps = 16/150 (10%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY-----MGSFEEGEKHQSVSH---G 127
+ +TSL+ +R +N G R+T V + + + Q H G
Sbjct: 23322 HTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAG 23381
Query: 128 EAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAI---TLENTLVILSTVAPDAGRYYVQ 184
+ P IA P P +WF G K+ S R+ + T L I T D G Y ++
Sbjct: 23382 RPVELVIP-IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23440
Query: 185 AVNDKNGDNKTSQPI-TLTVENVGGPADPI 213
KN TS+ I + ++ G P PI
Sbjct: 23441 L---KNVTGTTSETIKVIILDKPGPPTGPI 23467
Score = 38.9 bits (89), Expect = 0.056
Identities = 58/210 (27%), Positives = 85/210 (40%), Gaps = 29/210 (13%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSR-IAITLEN-----TLVILSTVAPDAGRYYVQAVNDKN 190
I P+P VTW++ G+KI P T E+ L I S D Y V A N K
Sbjct: 25341 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARN-KY 25399
Query: 191 GDNKTSQPITLTVENVGGPAD-PIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHI 249
G++ +T+T+ P D + P N G S V E + P L
Sbjct: 25400 GEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANAECQEGQS-VCFEIRVSGIPPPTLK- 25455
Query: 250 IWKKDGVLLSGGISDH-------NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYL 302
W+KDG LS G + L I + D GYY V +++ S A+L
Sbjct: 25456 -WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR---VTATNTAGSTSCQAHL 25511
Query: 303 SV----LEPPQF--VKEPERHITAEMEKVV 326
V + +F +E ERH+ +++K +
Sbjct: 25512 QVERLRYKKQEFKSKEEHERHVQKQIDKTL 25541
Score = 38.5 bits (88), Expect = 0.073
Identities = 48/178 (26%), Positives = 71/178 (39%), Gaps = 11/178 (6%)
Query: 401 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESG- 458
AP I TV G G P P W K G +I S + + P ++
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW--YWPEDNVC 2088
Query: 459 SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVI---KGTQASM 515
L+I D+ + A N G + A L+V A+ IT + Q V+ K T A+
Sbjct: 2089 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATF 2148
Query: 516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVI 572
C T +P V ++ W KDG + R+ DR L I + D Y+C ++
Sbjct: 2149 ECE-TSEPFVKVK--WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Score = 37.4 bits (85), Expect = 0.16
Identities = 40/183 (21%), Positives = 75/183 (40%), Gaps = 14/183 (7%)
Query: 40 EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGA 99
+G + +L E + W +N+E K + ++ I L +R N G
Sbjct: 24085 DGGKEILGYWVEYRQSGDSAWKKSNKERIK---DKQFTIGGLLEATEYEFRVFAENETGL 24141
Query: 100 LLQRQTEVQVAYMGSFEEGE------KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
R+T + + + E K + GEAA + +I P P + W+R G++
Sbjct: 24142 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKE 24200
Query: 154 IPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPA 210
+ S + ++ + +TL +++ D G Y A N+ G+ +TS + L P
Sbjct: 24201 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEV-GEVETSSKLLLQATPQFHPG 24259
Query: 211 DPI 213
P+
Sbjct: 24260 YPL 24262
Score = 37.0 bits (84), Expect = 0.21
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGL 370
EP R + E + C+ G P P + WY + ++ K RFR R DG L I
Sbjct: 1802 EPVRVLEGETAR---FRCRVTGYPQPKVNWYLNGQLIRKSK--RFRVRYDGIHYLDIVDC 1856
Query: 371 VPDDTGMFQCFARNAAGEVQTSTYLAV 397
DTG + A N G ++ L +
Sbjct: 1857 KSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 36.6 bits (83), Expect = 0.28
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 17/162 (10%)
Query: 56 LEFKWLHNN--------RELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEV 107
+E +WL NN ++ +R I + G YR I +++ + + ++
Sbjct: 6568 VEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK-----EARAKL 6622
Query: 108 QVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT 167
++A + ++ V G+ + P A +P+ + WF++ + + + +
Sbjct: 6623 ELAAAPKIKTADQDLVVDVGKPLTMVVPYDA-YPKAEAEWFKENEPLSTKTIDTTAEQTS 6681
Query: 168 LVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGP 209
IL D GRY + + +K+G K I L V +V GP
Sbjct: 6682 FRILEAKKGDKGRYKI-VLQNKHG--KAEGFINLKVIDVPGP 6720
Score = 36.2 bits (82), Expect = 0.36
Identities = 35/147 (23%), Positives = 56/147 (38%), Gaps = 10/147 (6%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE--------KHQSV 124
E +Y +T L +R + N G V E E + Q +
Sbjct: 10799 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 10858
Query: 125 SHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQ 184
G+ + A I P P+VTW ++ R P +RI +T + + + A + G Y
Sbjct: 10859 KVGDTLRLSAI-IKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10917
Query: 185 AVNDKNGDNKTSQPITLTVENVGGPAD 211
V + G +KT L ++ G P D
Sbjct: 10918 TVENPAG-SKTVSVKVLVLDKPGPPRD 10943
Score = 35.4 bits (80), Expect = 0.61
Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 59 KWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEG 118
KW+ + + +E +T L+ YR NR GA + ++ + + E
Sbjct: 7261 KWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 7316
Query: 119 EKHQSVSHGEAAVIRA-------PRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTL 168
E V ++A + P+P++TW + + RI I ++T+
Sbjct: 7317 EIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTV 7376
Query: 169 VILSTVAPDAGRYYVQAVN 187
I+ + D G Y ++AVN
Sbjct: 7377 TIVDSKRSDTGTYIIEAVN 7395
Score = 35.0 bits (79), Expect = 0.80
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE--NTLVILSTVAPDAGRY 181
V GE A R R+ +PQP+V W+ +G+ I S R + + + L I+ + D G
Sbjct: 1806 VLEGETARFRC-RVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1864
Query: 182 YVQAVN 187
V A N
Sbjct: 1865 KVTAEN 1870
Score = 35.0 bits (79), Expect = 0.80
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDN 193
I S P + WF+ GR+I S + +I ++L IL T D G Y +A N+ +
Sbjct: 4485 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVS 4544
Query: 194 KTSQPITLTVENVGG 208
T+ TLTV GG
Sbjct: 4545 CTA---TLTVTVPGG 4556
Score = 35.0 bits (79), Expect = 0.80
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 505 QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD-RNGSLHISQTWSGD 563
+S G+ A C V+ +T W KDG+ + R D ++ LHI D
Sbjct: 4756 ESEFVGSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSD 4812
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLP 590
G YTC + + +A L V +LP
Sbjct: 4813 AGEYTCVLRLGNKEKTSTAKLVVEELP 4839
Score = 34.7 bits (78), Expect = 1.0
Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 53 SWPLEFKWLHNNREL-TKFS--LEYRYMITSLDRTHAGFYRCIVRNRMGALLQ-RQTEVQ 108
S+ +E + L N R L FS LE + ++ L A +R I +N GA+ +
Sbjct: 15018 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15077
Query: 109 VAYMGSFEEGEKHQSVSHGEAAVIRAPR-------IASFPQPQVTWFRDGRKIPPSSRIA 161
+ E + V + +++A ++ P P + W +DG+++ ++++
Sbjct: 15078 ITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE 15137
Query: 162 ITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTII 218
I + LV + D+G Y + A N G K + + ++ G P P+A T +
Sbjct: 15138 IKIADFSTNLVNKDSTRRDSGAYTLTATN-PGGFAKHIFNVKV-LDRPGPPEGPLAVTEV 15195
Query: 219 IPPK 222
K
Sbjct: 15196 TSEK 15199
Score = 34.7 bits (78), Expect = 1.0
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILS---TVAPDAGRYYVQAVNDKNGDNKTSQ 197
PQ V W +DG+ + ++R+ ++ T+ LS D G Y + N +
Sbjct: 19050 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV---SNSAGSITV 19106
Query: 198 PITLTVENVGGPADPI 213
PIT+ V + GP PI
Sbjct: 19107 PITIIVLDRPGPPGPI 19122
Score = 33.5 bits (75), Expect = 2.3
Identities = 57/314 (18%), Positives = 111/314 (35%), Gaps = 26/314 (8%)
Query: 94 RNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
R + GA Q E M SF +K + ++ E + + + S +V++F +
Sbjct: 4256 RIQQGAKTSLQEE-----MDSFSGSQKVEPITEPE---VESKYLIS--TEEVSYFNVQSR 4305
Query: 154 IPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENV-GGPADP 212
+ +T ++S D + + + ++ T + T+ ++ GG
Sbjct: 4306 VKYLDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKE 4365
Query: 213 IAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG-----ISDHNR 267
P I P +T G + NA+ + W + L+ + D N
Sbjct: 4366 DGPMIHTPLVDTVSEEGDIVHLTTSITNAK-----EVNWYFENKLVPSDEKFKCLQDQNT 4420
Query: 268 RLTIPNPTGSD--AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
+ + ++ G Y CEA+ S + + + P +K + + +
Sbjct: 4421 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP--VIKRKIEPLEVALGHL 4478
Query: 326 VDIPCQAKGVPPPSITWYKDAA-VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARN 384
C+ + P W+K + E +K + + L+I D G + C A N
Sbjct: 4479 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASN 4538
Query: 385 AAGEVQTSTYLAVT 398
G V + L VT
Sbjct: 4539 EYGSVSCTATLTVT 4552
Score = 33.5 bits (75), Expect = 2.3
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRI-AITLENT--LVILSTVAPDAG 179
+V GE + P I P P VTW +D + ++R+ A + EN L I D G
Sbjct: 15786 TVLAGEDLKVDVPFIGR-PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVG 15844
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPI 213
Y V+ N +T I L + G P P+
Sbjct: 15845 HYVVKLTNSAGEAIETLNVIVL--DKPGPPTGPV 15876
Score = 33.1 bits (74), Expect = 3.0
Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 18/155 (11%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQV-----AYMG-------SFEEGEK 120
E +++I+ L + +R RN +G++ V +Y G + E K
Sbjct: 20452 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVK 20511
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR 180
+++ G + +RA I+ P P + W++D +++ ++ + + ENT + S + DA R
Sbjct: 20512 YRA---GTSVKLRAG-ISGKPAPTIEWYKDDKELQTNALVCV--ENTTDLASILIKDADR 20565
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAP 215
K + S T+ V+ + P P P
Sbjct: 20566 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGP 20600
Score = 31.6 bits (70), Expect = 8.9
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 1/86 (1%)
Query: 427 GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA 486
G P + W + L + + +L SL + D+G TC ATN G D
Sbjct: 1684 GDPTMVVEWLHDGKPLEAAN-RLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHT 1742
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQ 512
SA L+V + + Q KG Q
Sbjct: 1743 SATLIVKDEKSLVEESQLPEGRKGLQ 1768
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 246 bits (629), Expect = 1e-64
Identities = 395/1726 (22%), Positives = 665/1726 (38%), Gaps = 198/1726 (11%)
Query: 147 WFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
W ++G ++P +R++ ++ + L I PD G Y V A DK S L +
Sbjct: 6269 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDK------SVAELLII 6322
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS 263
E APT + V + C + K ++ W ++G + G
Sbjct: 6323 E---------APTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKK 6370
Query: 264 ------DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE-PER 316
RL I + D Y C R S V + ++ PPQ + E P
Sbjct: 6371 YKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGA 6430
Query: 317 HIT--AEMEKVVDIPCQAKGVPPPSITWYKD-AAVVEVEKLTRFRQRNDGGLQISGLVPD 373
+ AE+ K + W ++ VV+ +K + LQI + P
Sbjct: 6431 DVVFLAELNK-----------DKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR 6479
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D G ++ A++ E + LA AP I D V G + + P+
Sbjct: 6480 DQGEYRFIAKDK--EARAKLELAA---APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEA 6534
Query: 434 TWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW 493
W K L++ ++ T E S I D G Y + N G E +L V
Sbjct: 6535 EWFKENEPLSTKTID----TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV- 6589
Query: 494 ARTRITKPPQDQSVIKGTQASMVCG----VTHDPRVTIRYIWEKDGATLGTESHPRIRLD 549
+ P ++ V + + +T I Y+ E+ T + D
Sbjct: 6590 --IDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV---LATD 6644
Query: 550 RNGSLHISQTWSGDIGT-YTCRV-----ISAGGNDSRSAHLRVRQLPHAPEHPV-ATLST 602
R S + T G Y RV + G + R P P+ T++
Sbjct: 6645 RAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITD 6704
Query: 603 VERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSY 661
V R ++LTW P +DG + + Y++E+ + + +V + S TV +V + Y
Sbjct: 6705 VNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEY 6764
Query: 662 QFRLCAVNDVGKGQFSKDTE--RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
FR+ A N +G G+ S T +V+ P E P+ PP N+ +S +T S+ ++W+PP +
Sbjct: 6765 SFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSSVQLKWEPPLKDGG 6823
Query: 720 NGILKGYIIRYCLAGLP--VGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
+ IL GYII C G + K + + LE Y V+A N AG+
Sbjct: 6824 SPIL-GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK---GNKYLYRVSAENKAGVSD 6879
Query: 778 YSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837
S + T P ++ A I P+P I + GY
Sbjct: 6880 PSEILGPLTADDAFVEPTMDLSAFKDGLEVI-----VPNPITILVPSTGYP--------- 6925
Query: 838 EEVTMVTARPNFQDSI-HVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG 896
TA F D + G +K + Y V+ + D T +L + + G
Sbjct: 6926 ----RPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981
Query: 897 PVG-----------HLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR-TNTRVT 943
+ L F +I S+ ++W+ P + G LTGY + E +R T T+V
Sbjct: 6982 EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVM 7041
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA--STISSGVPPELPGPPTNLGI 1001
++ + LE+ V L Y +V A G G+ + ++ P +P PP N+
Sbjct: 7042 DFVTD--LEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKW 7099
Query: 1002 SNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS-MEVP 1059
+ S+ L + P DG + I ++VE ++W+ EP A + MEV
Sbjct: 7100 RDRTANSIFLTWDPPKNDGGSRIKGYIVER---CPRGSDKWVAC----GEPVAETKMEVT 7152
Query: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTL--QAPPDM-----APANVSLRTASETS 1112
L Y++R++ +N G S PS+P+ +IQ + Q P++ A ++++ ++
Sbjct: 7153 GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIE 7212
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER--DYTIEDLEEWTE 1170
L G PE KI ++++D K + + V + TI D +
Sbjct: 7213 L--------PATVTGKPEP---KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7261
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
++A N G T V P T+ S L+ W+ P D
Sbjct: 7262 GTYIIEAVNVCGRA----TAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP-PRDDGGS 7316
Query: 1231 LVLGYKVMYKEKDSDTQPRF-WLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-S 1288
+ Y V + DS+ + V+ + ++ +L +Y+ +V A G G P
Sbjct: 7317 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF---RVAAENMYGVGEPVQ 7373
Query: 1289 HPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTA 1348
PI + D PGPP + ++ +V L W P G + RL+ T
Sbjct: 7374 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7433
Query: 1349 TVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRP 1406
+ Y GL + Y FR+ A+ G G+ +++ ++ + D P PP +P
Sbjct: 7434 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKP 7493
Query: 1407 MVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDR 1465
V +DV SV L+W +P DG + + Y I+ + + W + V + ++
Sbjct: 7494 TV--KDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVP--TTQHLLPG 7549
Query: 1466 LKPFTSYKFRVKATNDIGDSEFSEESES-LTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
L Y FRV+A N G+SE SE S+ L + P P L V T + ++W
Sbjct: 7550 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 7609
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
P +D + + + R++ +G W + + + LT+
Sbjct: 7610 PEKDG-GSPITNYIVEKRDVRRKG---------------WQTVDTTVKDTKCTVTPLTEG 7653
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT--AAPRNVVVHGATATQLDV 1642
L Y R++ NA+G+ + ++ + + T P + V T +D+
Sbjct: 7654 SL--------YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7705
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
WEPP D IQ Y I E + KT + + ++ ++ T V A
Sbjct: 7706 KWEPPKNDG-GRPIQRYVIEKKERLGTRWVKAGKTAG-PDCNFRVTDVIEGTEVQFQVRA 7763
Query: 1703 FNAAGDGPRSTPTQ---GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
N AG G S PT+ + + PS P + ++ + ++W+ P+ G + GY
Sbjct: 7764 ENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYH 7823
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD-LAEGVTYRFRIRA 1803
+ E C PV G K + V+ + L KV++ + Y R+RA
Sbjct: 7824 V--EMC-PV-GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 7865
Score = 225 bits (573), Expect = 4e-58
Identities = 433/1960 (22%), Positives = 731/1960 (37%), Gaps = 276/1960 (14%)
Query: 72 LEYRYMITSLDRTHAGFYRCIVRNRMGAL---------LQRQTEVQVAYMGSFEEGEKHQ 122
+E ++ ++ L +R I +N GA+ + + EV++ + +
Sbjct: 17079 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 17138
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTLVILSTVAPDAG 179
V+ GE + A + P P + W R ++I S+R I + L++ + D G
Sbjct: 17139 VVNAGETFRLEAD-VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 17197
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVA 239
+Y ++A N S P+ + V + GP P V TSE
Sbjct: 17198 QYILRA---SNVAGSKSFPVNVKVLDRPGP----------PEGPVQVTGVTSE------- 17237
Query: 240 NARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAG-YYECEAVLRSSSVPSVVR 298
K + W L G SD + + T A E V S V ++
Sbjct: 17238 ------KCSLTWSPP---LQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLE 17288
Query: 299 G---AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV------ 349
G + + V EP M+ +P K + +I KD+ V
Sbjct: 17289 GNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIA--KDSMTVCWNRPD 17346
Query: 350 ----------EVEKLTRF---------RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQ 390
VEK R R+ D L+++GL D F+ A NAAG +
Sbjct: 17347 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17406
Query: 391 TS-TYLAVTSIAPNITRGP------LDST-----------VIDGMSVVLA-----CETSG 427
S + + P GP +D+T + DG S +L C+
Sbjct: 17407 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 17466
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA- 486
+T Q G R+ T E L T + C A N G+ EA
Sbjct: 17467 EEWQIVTPQTGLRV-----------TRFEISKL----TEHQEYKIRVC-ALNKVGLGEAT 17510
Query: 487 SADLVVWARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
S V ++ P D + ++ S + R T W ++
Sbjct: 17511 SVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---- 17566
Query: 541 ESHPRIRLDRNGS---LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPV 597
E ++++++ + L I D G Y ++ ++ G+ S ++V P P++
Sbjct: 17567 EFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-- 17624
Query: 598 ATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLV 656
+ V + + L W P DG + + Y+++ E+ ++S K TS V+ L
Sbjct: 17625 LAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLT 17683
Query: 657 PARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPE 716
Y FR+ A N+ G G + + V E P +PP V + + S + W+ P
Sbjct: 17684 EGAIYYFRVMAENEFGVGVPVETVDAVKAAE--PPSPPGKVTLTDVSQTSASLMWEKPEH 17741
Query: 717 SHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG 776
+ +L GY++ G ++ + ++ V N ++ L Y+ V AYN G
Sbjct: 17742 DGGSRVL-GYVVEMQPKGTE---KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKG-- 17795
Query: 777 VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF-------INGINQGYKL 829
++ + GVP + + T +++ +N S Q I I +
Sbjct: 17796 -----KSDPRVLGVPVIA-----KDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 17845
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
I+W ++ E T R N +++ V +K+ + T +T L
Sbjct: 17846 ISW--VKDGEPLKQTTRVNVEETA-TSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 17902
Query: 890 THEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLP 947
+ PG PVG + F E+ + +SW+ P G ++ Y + R T T ++
Sbjct: 17903 IVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMV 17958
Query: 948 NVTL---EYRVTGLTALTTYTIEVAAMTSKGQ-GQVSASTISSGVPPELPGPPTNLGISN 1003
+ T+ ++T L T Y + A G+ + + + P + PGPP +++
Sbjct: 17959 SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTS 18018
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I + +Q+ P DG T I + +E + E L + + L+
Sbjct: 18019 ISKDQMLVQWHEPVNDGGTKIIGYHLEQK-----EKNSILWVKLNKTPIQDTKFKTTGLD 18073
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPE 1122
Y F++ NIVG PS+ S + P P + ++ L+W +
Sbjct: 18074 EGLEYEFKVSAENIVGIGKPSKVSECF--VARDPCDPPGRPEAIVITRNNVTLKW---KK 18128
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G + GY ++ + G+ + + +E ++T+ L E Y +V A NA G
Sbjct: 18129 PAYDGGSKITGYIVE-KKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 18187
Query: 1183 --SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE--VPEADRNGLVLGYKVM 1238
S P + R+ + + N S ++V E V EAD G + V
Sbjct: 18188 NFSEPSDSSGAITARDEIDA---PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 18244
Query: 1239 YKE-KDSDTQPRFWLVEGNSSRSAQL------TGLGKYVLYEVQVLAFTRIGDGSPSHPP 1291
K+ K+ + ++ ++ + T G+Y+L V G P
Sbjct: 18245 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNV--------GGTKSIP 18296
Query: 1292 ILERTLDDVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATV 1350
I + LD PGPP G L V L W PP G +++ I + T+ + V
Sbjct: 18297 ITVKVLDR-PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 18355
Query: 1351 EVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTT-EKRDRPQPPSRPMVQ 1409
A Y T L P + Y+FR+ A + G GE E+ VT P PPS P V
Sbjct: 18356 ST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVS 18414
Query: 1410 QEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKP 1468
+ S++++W P DG + + Y ++ R+ RW + + V L
Sbjct: 18415 A--ITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDL-RLRVTGLTE 18471
Query: 1469 FTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAE 1527
SY+FRV A N G E SE S A P P+ VT + +SV + W P
Sbjct: 18472 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKP-- 18529
Query: 1528 DKINGILLGFRIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
+Y+G ++G+ + W T ++ Q+
Sbjct: 18530 -----------------IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG------KQF 18566
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAVP------TAAPRNVVVHGATA 1637
+ L ++ Y R+ N+ G G P++ P V E + A R VVV A+A
Sbjct: 18567 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18626
Query: 1638 T-QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE-NSVKLKNLTGYTA 1695
T +L VT + P WE G LT+R + + + + N+T + +
Sbjct: 18627 TLRLFVTIKGRPEPEVK----------WEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDS 18676
Query: 1696 YMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILE 1755
++ N +G T +PSAP ++ E+ SV +SWE P G
Sbjct: 18677 GRYNLTLENNSGS---KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGA-- 18731
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN 1815
++ + K + ++++L EG +Y FR+ A YG + A
Sbjct: 18732 --KITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASN-EYGIGLPAE 18788
Query: 1816 VTTGPGEGA--PGPPG-VPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDI 1871
TT P + + P PPG V ++ + I W + G IT YV+E + W
Sbjct: 18789 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 18847
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
+V + ++ L G Y FRV AVN+ G P
Sbjct: 18848 C-----TQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDP 18882
Score = 218 bits (556), Expect = 4e-56
Identities = 418/1900 (22%), Positives = 731/1900 (38%), Gaps = 252/1900 (13%)
Query: 136 RIASFPQPQVTWFRDGRKIPPS----------SRIAITLENTLVILSTVAPDAGRYYVQA 185
+I P P +TWF+ K P + +++ + TLVI + D G Y + A
Sbjct: 9642 KIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITA 9701
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTII------------IPPKNTSVVAGTSEV 233
VN+ +K + + +G P P+ P PPK+ T+ V
Sbjct: 9702 VNNLGTASKE-----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9756
Query: 234 TLECVANARPLIKLHIIWKKDGVLLSGGISDHNR--RLTIPNPTG-SDAGYYECEAVLRS 290
+ AN + + + K+ + + H R+ N G + E E
Sbjct: 9757 IEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 9816
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY--KDAAV 348
SVP + P +T E+ + G P + W KD
Sbjct: 9817 FSVPGAP--------DKPTVSSVTRNSMTVNWEEP-----EYDGGSPVTGYWLEMKDTTS 9863
Query: 349 VEVEKLTR--FRQRNDG-GLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIA 401
+++ R + G +++GL+ F+ +A NAAG + + A IA
Sbjct: 9864 KRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 9923
Query: 402 P---------NITRGPLD----STVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQ 448
P + T+ D + DG S V W+KG+ G+
Sbjct: 9924 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 9983
Query: 449 LPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE-ASADLVVWARTRITKPP----- 502
+ T L+ G+ + A N G+ E V+ + R+ P
Sbjct: 9984 V--VTGLKEGAFY----------KFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 10031
Query: 503 --QDQSVIK-GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
+D+ V+ G ++ V+ P T+ W + TL E+ + S+ I
Sbjct: 10032 SVRDRIVVHAGGVIRIIAYVSGKPPPTVT--WNMNERTLPQEATIETTAI-SSSMVIKNC 10088
Query: 560 WSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-G 618
G Y+ + G ++ + V +P P + + LTW P D G
Sbjct: 10089 QRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA-HNLTNESCKLTWFSPEDDG 10147
Query: 619 NSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS 677
SP+ Y++E E++ WT + +V + + TV+GL+ ++Y FR+ A N +G G F
Sbjct: 10148 GSPITNYVIEKRESDRRAWTPVTYTVTRQ--NATVQGLIQGKAYFFRIAAENSIGMGPFV 10205
Query: 678 KDTERVSLPEEPPTAP--PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGL 735
+ +E + + EP T P P+++ T ++ + W PP + G II Y L
Sbjct: 10206 ETSEALVI-REPITVPERPEDLEVKEVTKNTVTLTWNPP--KYDGG---SEIINYVLESR 10259
Query: 736 PVGYQ-FKNITDADV--NNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPT 792
+G + F +T+ ++ ++ L YE V+A N G G S T +
Sbjct: 10260 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKD--E 10317
Query: 793 VPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQ----EEEVTMVTARPN 848
+ P +H + + TIR +G + ++W ++ E++ T + P
Sbjct: 10318 LAPPTLHLDFRDKLTIRVGEAFALTGRYSG--KPKPKVSWFKDEADVLEDDRTHIKTTPA 10375
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILD 908
++ + + + + + V+ +T G R V + PVG +SF E+
Sbjct: 10376 ---TLALEKIKAKRSDSGKYCVVVENST---GSRKGFCQVNVVDRPGPPVGPVSFDEVTK 10429
Query: 909 TSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVTLEYRVTGLTALTTYTI 966
+ +SW+ P + G +T Y I +E + VT T +V+ L Y
Sbjct: 10430 DYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC--KVSKLLEGKDYIF 10487
Query: 967 EVAAMTSKGQGQVSASTISSGVPPE----LPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
+ A G +S +S + + +P P ++ + S + + +DG
Sbjct: 10488 RIHAENLYG---ISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKP 10544
Query: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
I+ +++E + + + W + + P + VPDL Y FR+ N +G P
Sbjct: 10545 ITNYILEKRETM---SKRWARVTKDPIHPYTK-FRVPDLLEGCQYEFRVSAENEIGIGDP 10600
Query: 1083 SQPSRKIQTLQ--APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR 1140
S PS+ + A P P N + S+ L W P ++G + +GY ++Y +
Sbjct: 10601 SPPSKPVFAKDPIAKPS-PPVNPEAIDTTCNSVDLTWQP---PRHDGGSKILGYIVEYQK 10656
Query: 1141 -SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRE 1196
D + +H + E Y + L + Y+ +V A NA G + + V+ + R
Sbjct: 10657 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10716
Query: 1197 SVPS-------SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD--TQ 1247
P + ++ T S +++ P KV +K++D D T+
Sbjct: 10717 EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP-----------KVTWKKEDRDAPTK 10765
Query: 1248 PRFWLVEGNSS---RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1304
R + S R+A G Y L + + + S ++ + D PGPP
Sbjct: 10766 ARIDVTPVGSKLEIRNAAHEDGGIYSL---------TVENPAGSKTVSVKVLVLDKPGPP 10816
Query: 1305 MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
+ E+R S L W+ P G ++ + R + +A + + + + + A
Sbjct: 10817 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK-KSHFAKH 10875
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSW- 1422
L + YLFR+ A+ + G G E + D PP P + DV V L W
Sbjct: 10876 LNEGNQYLFRVAAENQYGRGPFVET-PKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 10934
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
+P DG SP+ Y ++ +E + W + +V L+ +Y+FRVKA N +
Sbjct: 10935 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC---VVTGLQQGKTYRFRVKAENIV 10991
Query: 1483 GDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK----INGILL--G 1536
G PD + P L+ PP+ + I G+++ G
Sbjct: 10992 G--------------LGLPD------TTIPIECQEKLV---PPSVELDVKLIEGLVVKAG 11028
Query: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWA------ELTSMYSMRNLSRPSLTQYELDNLN 1590
+R+ ++ RG+ P A W + Y++ + S+ + N
Sbjct: 11029 TTVRFPAII---------RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT--IKNCL 11077
Query: 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+ E +++V NA G + V PT P N++ T + ++W+PP D
Sbjct: 11078 RRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINIL--DVTPEHMTISWQPPK-D 11133
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
+ Y + + ++ T V + ++ +K+ +L Y+ V A N G GP
Sbjct: 11134 DGGSPVINYIVEKQDTRKD--TWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGP 11191
Query: 1711 R--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPV 1767
STPT + + + PS P +++T + VSW P+ G + GY Y V
Sbjct: 11192 PLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGY---YMERREV 11248
Query: 1768 DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTTGPGEG 1823
G K V V+ + L +V L EG TY FR+ A+ P + P +
Sbjct: 11249 TG--KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK- 11305
Query: 1824 APGPPGVPIIVRYSSAIA-IHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
PGPP P + S A + W+ G PI YV+E + W+ + KD + +
Sbjct: 11306 PPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD--ELIR 11363
Query: 1882 SYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
F + L G Y FR+ A N G G P ++SV A+
Sbjct: 11364 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAK 11403
Score = 215 bits (548), Expect = 3e-55
Identities = 424/1882 (22%), Positives = 697/1882 (37%), Gaps = 278/1882 (14%)
Query: 378 FQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMSVVLACETSGAP 429
F+ A+N AG E +S + I P + + +I G + SG P
Sbjct: 22119 FRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRP 22178
Query: 430 RPAITWQKGE-RILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASA 488
P +TW+ E R+ + V + T + +L + + D+G Y N+ GV S
Sbjct: 22179 APKVTWKLEEMRLKETDRVSIT--TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV 22236
Query: 489 DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--IRYIWEK--DGATLGTESHP 544
+VV R P + S + + G D T YI EK G T +
Sbjct: 22237 TVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNS 22296
Query: 545 RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLST-- 602
++ + H+++ Y+ RV S + + P EHP S
Sbjct: 22297 SVKRTQIKVTHLTKYME-----YSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPT 22348
Query: 603 ------VERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGL 655
V A+++ W +P+ DG S +I Y +E E N V V + V GL
Sbjct: 22349 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22408
Query: 656 VPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPP 715
V YQFR A+N G + S + R + + P AP + + T ++ + W P
Sbjct: 22409 VEGLEYQFRTYALNAAGVSKAS-EASRPIMAQNPVDAPGRPEVTDV-TRSTVSLIWSAPA 22466
Query: 716 ESHQNGILKGYII-RYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSA 773
+ ++ GYII R ++ + G K N T N + L YE V A N+A
Sbjct: 22467 YDGGSKVV-GYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAA 22525
Query: 774 GLGVYSSKVTEWTLQGVPTVPP-----GNVHAEATNSTTIRFTWNAPSPQFINGINQGYK 828
G+ S+ T PP +H + TIR + + G + K
Sbjct: 22526 GVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV---TIRAGSDLVLDAAVGGKPEP-K 22581
Query: 829 LIAWEPEQE----EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRST 884
+I + ++E E+V++ I S K+T + G ++
Sbjct: 22582 IIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA-------SGTKAV 22634
Query: 885 PQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVT 943
+V+ D PGP G L+ S + ++W P E G +T Y + E +R N +
Sbjct: 22635 SVMVKVL-DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 22693
Query: 944 HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG-QVSASTI---SSGVPPELPGPPTNL 999
TL Y VT L Y V A+ G G V + I +S P PG P +
Sbjct: 22694 EG-ECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEV 22752
Query: 1000 GISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEV 1058
G G + +Q+ +P DG IS +LV+ + + W +++ D R ++V
Sbjct: 22753 GT---GKEHIIIQWTKPESDGGNEISNYLVDKREK---KSLRWTRVNKDYVVYDTR-LKV 22805
Query: 1059 PDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP----PDMAPANVSLRTASETSLW 1114
L Y FR+ VN G S PS+ S I + P AP V S + W
Sbjct: 22806 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 22865
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
+ M Y+G + VGY ++ D H ++T+ DL+ +Y +
Sbjct: 22866 TKPM------YDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFR 22919
Query: 1175 VQAFNAIGSGPWSQTVVGRT---RESVPSSGPTN-----VSALATTSSSMLVRWSEVPEA 1226
V A N G +S+++ R +P + V+ A S ++V S P
Sbjct: 22920 VAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP 22979
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
+ + ++ D R + +++ S L + K Y+
Sbjct: 22980 ---------VITWSKQGIDLASRAII---DTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23027
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+L + D PGP + EV SV + W+ P G + I +
Sbjct: 23028 KKSATVLVKVYD-TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRA 23086
Query: 1347 TATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPS 1404
TV S Y +GL ++Y FR+ + G GE E V+ +E P P+
Sbjct: 23087 FKTVTTKC-SKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PLVPA 23142
Query: 1405 RPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
+ ++ DV +V L+WE P DG S + Y ++ + + RW + ++ V
Sbjct: 23143 K--LEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW-MKVVTLKPTVLEHTV 23199
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRW 1522
L Y FR++A N+ G SE E ++T PTI LS P T V
Sbjct: 23200 TSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRV--LPTIDLSTMPQKTIHV---- 23253
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLT 1582
PA + ++ + G P A+W S +R R ++
Sbjct: 23254 --PAGRPVELVI------------------PIAGRPPPAASWFFAGS--KLRESERVTVE 23291
Query: 1583 QYELDNLNKHRRYEIRMSVYNAVGE---------GPSSPPQEVFV-GEAVPTAAPRNVVV 1632
+ K + IR + GE G +S +V + + P P + +
Sbjct: 23292 TH-----TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP--IKI 23344
Query: 1633 HGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTG 1692
AT + ++WEPP LD + GY + +A R +++ ++ K LT
Sbjct: 23345 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTE 23401
Query: 1693 YTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Y+ VAA N G G +S + ++ P P +++ +++ + ++W P+
Sbjct: 23402 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23461
Query: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
G V+ + + + W++V + +T R R+ T G
Sbjct: 23462 GG---------------SQVTGYIVERKEVRADRWVRVNKVPVTMT---RYRSTGLTEGL 23503
Query: 1811 EIEANVTT--GPGEGAPGPPGVPIIVR-----------------YSSAIAIHWS-SGDPG 1850
E E VT G G P P PI+ +++++ WS D G
Sbjct: 23504 EYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEG 23563
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
+T Y+IE + D+ W P ++ YT + L G Y FRV+A N G G
Sbjct: 23564 GSKVTGYLIEMQKVDQHEWT-KCNTTPTKIREYTLTH--LPQGAEYRFRVLACNAGGPGE 23620
Query: 1911 PSSPSQSV--------PAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAK 1962
P+ +V P + + Y+E F+ ++ L + I+G+ K
Sbjct: 23621 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRL--------TIPIKGKPFPICK 23672
Query: 1963 KTDSGNSAKSGAL-----GHSEMMSLD----ESSFPALELNNRRLSVKNSFCRKNGLYTR 2013
T G A+ H+E++ + +S L L N+ C K +Y +
Sbjct: 23673 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENK--------CGKKAVYIK 23724
Query: 2014 SPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSF 2073
SP S E +Y+D I S ++ +P +D G+D +
Sbjct: 23725 VRVIGSPN----SPEGPLEYDD-IQVRSVRVSWRPP--ADDGGADI---------LGYIL 23768
Query: 2074 VNHYISDPTYYNSWRRQQ------KGISRAQAYSYTESDSGEPDHTTVTNSTSTQQGSLF 2127
+ +Y R + KG+ Y + S + Q +
Sbjct: 23769 ERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVS--------------AENQFGIS 23814
Query: 2128 RPKASRTP----TPQNPPNPPS 2145
+P S P TP NPP PPS
Sbjct: 23815 KPLKSEEPVTPKTPLNPPEPPS 23836
Score = 213 bits (541), Expect = 2e-54
Identities = 413/1864 (22%), Positives = 693/1864 (37%), Gaps = 243/1864 (13%)
Query: 147 WFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTV 203
WFR+ I SS+ I ++ TL I D Y V N + + K++ + +
Sbjct: 6175 WFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEE 6234
Query: 204 ENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV------L 257
E++ I+ P K+ + S VT C N + + + W K+G
Sbjct: 6235 EDL---------RIVEPLKDIETMEKKS-VTFWCKVNR---LNVTLKWTKNGEEVPFDNR 6281
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP-QFVKEPER 316
+S + + LTI + D G Y ++ + SV A L ++E P +FV+ E
Sbjct: 6282 VSYRVDKYKHMLTIKDCGFPDEGEY----IVTAGQDKSV---AELLIIEAPTEFVEHLED 6334
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ---ISGLVPD 373
E + V CQ ++ WY++ E+++ +++ DG + I D
Sbjct: 6335 QTVTEFDDAV-FSCQLSR-EKANVKWYRNGR--EIKEGKKYKFEKDGSIHRLIIKDCRLD 6390
Query: 374 DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
D + C + + L V I I R P D G VV E + + +
Sbjct: 6391 DECEYACGVEDRKSRAR----LFVEEIPVEIIRPPQDILEAPGADVVFLAELN-KDKVEV 6445
Query: 434 TWQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAGTYTCLATNSRGVDEASADL 490
W + ++ G + + G L I D G Y +A + EA A L
Sbjct: 6446 QWLRNNMVVVQGD----KHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKL 6497
Query: 491 VVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR 550
+ A +I QD V G +MV V +D W K+ L T++
Sbjct: 6498 ELAAAPKIKTADQDLVVDVGKPLTMV--VPYDAYPKAEAEWFKENEPLSTKTIDTTA--E 6553
Query: 551 NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER--RAI 608
S I + GD G Y + + G +L+V +P PV L E +
Sbjct: 6554 QTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPG----PVRNLEVTETFDGEV 6609
Query: 609 NLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPAR-SYQFRLC 666
+L W +P DG S +I Y++E + T +LA+ ++ TV GL Y FR+
Sbjct: 6610 SLAWEEPLTDGGSKIIGYVVERRDIKRK-TWVLATDRAESCEFTVTGLQKGGVEYLFRVS 6668
Query: 667 AVNDVGKGQ-FSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKG 725
A N VG G+ D + + PP NV + + + W+ PPE +
Sbjct: 6669 ARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWE-PPEYDGGAEITN 6727
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
Y+I + + A+ + + D++ Y V A N G+G S T +
Sbjct: 6728 YVIE-LRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVG-KPSAATPF 6785
Query: 786 TLQGVP---TVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
P PP N+ + ++++ W P + G ++ + E+ EE
Sbjct: 6786 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK------DGGSPILGYIIERCEEGKD 6839
Query: 843 VTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHL 901
R N + + + V+GL+K +Y V G V ++ GP+
Sbjct: 6840 NWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG---------VSDPSEILGPL--T 6888
Query: 902 SFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLE----YRVTG 957
+ ++ ++ +S + G + + I T + LE ++
Sbjct: 6889 ADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKT 6948
Query: 958 LTALTTYTIEVAAMTSKG----QGQVSASTISSGVPPEL---PGPPTNLGISNIGPRSVT 1010
L+A I + + KG + + TIS + + P P L +I SV
Sbjct: 6949 LSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVH 7008
Query: 1011 LQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSF 1069
L + P DG + ++ ++VE + + W + + + VPDL Y F
Sbjct: 7009 LTWEPPDDDGGSPLTGYVVEKR---EVSRKTWTKVMDFVTDLE---FTVPDLVQGKEYLF 7062
Query: 1070 RMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
++ N G P+ + T PD P NV R + S++L W P + +G
Sbjct: 7063 KVCARNKCGPGEPAYVDEPVNMSTPATVPD-PPENVKWRDRTANSIFLTWDP---PKNDG 7118
Query: 1128 NPESVGYKIKY--SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
GY ++ SD V + ++E + LEE Y +V+A N G
Sbjct: 7119 GSRIKGYIVERCPRGSDKWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASK 7174
Query: 1183 -SGPWSQTVVGRTRE--------------SVPSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
S P + T+E +V + + A T + W++
Sbjct: 7175 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKA---- 7230
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++L ++ + +V+ S + G Y++ V V
Sbjct: 7231 --DMILKQDKRITIENVPKKSTVTIVDSKRSDT------GTYIIEAVNVCG--------- 7273
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILA----------YQIT 1337
++E + D PGPP +V S L W PP G + ++
Sbjct: 7274 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 7333
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKR 1397
H+L++T +T + AT L P Y+FR+ A+ G GE +A +T + +
Sbjct: 7334 HKLSSTVKDT-----------NFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ 7382
Query: 1398 -DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
D P PP+R ++ D+ +V L+W EP DG SP+ Y ++ + + +W + +
Sbjct: 7383 FDPPGPPTR--LEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW-VRCNKMP 7439
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVT 1511
+++ V L Y+FRV A N G + S+ +E + P PT+ V
Sbjct: 7440 VKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDV- 7498
Query: 1512 PHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMY 1571
TSV + W P D G +I + + + W
Sbjct: 7499 --GKTSVRLNWTKPEHDG------GAKI----------ESYVIEMLKTGTDEW------- 7533
Query: 1572 SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAV-PTAAPRN 1629
+R TQ+ L L + + Y R+ N GE PS P V E + P + PR
Sbjct: 7534 -VRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRW 7592
Query: 1630 VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKN 1689
+ V T D+ W P D I Y + + +R + V T + + +
Sbjct: 7593 LEVINITKNTADLKWTVPEKDG-GSPITNYIVEKRDVRRKG-WQTVDTT-VKDTKCTVTP 7649
Query: 1690 LTGYTAYMVSVAAFNAAGDGPRS---TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEA 1746
LT + Y+ VAA NA G + + P P ++ ++T V++ WE
Sbjct: 7650 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEP 7709
Query: 1747 PQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTF 1806
P+ G R V E + ++ V +V D+ EG +F++RA+
Sbjct: 7710 PKNDGG-RPIQRYVIEKKERLG--TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENE 7766
Query: 1807 TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA----IAIHWSSGDP-GKGPITRYVIEA 1861
E PP P+ + + A IAI W + G PI Y +E
Sbjct: 7767 AGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM 7826
Query: 1862 RPSDEGLWDIL----IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
P W + IKD+ +V + + P Y RV AVN G PS S++
Sbjct: 7827 CPVGTEKWMRVNSRPIKDLKFKVE------EGVVPDKEYVLRVRAVNAIGVSEPSEISEN 7880
Query: 1918 VPAQ 1921
V A+
Sbjct: 7881 VVAK 7884
Score = 213 bits (541), Expect = 2e-54
Identities = 357/1619 (22%), Positives = 619/1619 (38%), Gaps = 152/1619 (9%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQ--TSTYLAVTSI----APNITRGPLDSTVI---DGM 417
+SGLV D F+ ARNAAG + + A+T+ APN + P VI G
Sbjct: 18167 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGE 18226
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ VL + G P P + W K + L + ++ + ++ +L++ +D G Y
Sbjct: 18227 TFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 18286
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT------IRYIW 531
+N G + V R PP+ + G A C + +P + YI
Sbjct: 18287 SNVGGTKSIPITVKVLDRPG---PPEGPLKVTGVTAEK-CYLAWNPPLQDGGANISHYII 18342
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAHLRVR 587
EK + + + + +L+ T Y RV++ G S +
Sbjct: 18343 EKRETSRLSWTQVSTEVQ---ALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC 18399
Query: 588 QLPHAPEHPVAT--LSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVD 644
P+ P P +T +S + + ++ +TW +P D G + + YILE +
Sbjct: 18400 N-PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT 18458
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQNVIASGRT 703
+ V GL SY+FR+ A N G G+ S+ + + P PP N + +
Sbjct: 18459 LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 18518
Query: 704 NQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGL--------PVGYQFKNITDADVNNLLL 754
S+ + W P + G +KGY++ A P G Q K T +
Sbjct: 18519 RSSVSLAWSKP--IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN-- 18574
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
T Y + A NS G+G ++ Q + P + +A + +A
Sbjct: 18575 ------TEYNFRICAINSEGVGEPATLPGSVVAQ--ERIEPPEIELDADLRKVVVLRASA 18626
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
F+ + + WE + E + A+ S + + + +F ++
Sbjct: 18627 TLRLFVTIKGRPEPEVKWE--KAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 18684
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G ++ VR + PV +L+ E+ S+ +SW+ P G +T Y +
Sbjct: 18685 NNSGS--KTAFVNVRVLDSPSAPV-NLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18741
Query: 934 EYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R +T+ T +R+ L +Y V A G G + A T E
Sbjct: 18742 ETTRKAYATITNNCTKTT--FRIENLQEGCSYYFRVLASNEYGIG-LPAETTEPVKVSEP 18798
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
P PP + + ++ + T+++ +P DG + I+ ++VE Q E+W Q+
Sbjct: 18799 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKT-- 18853
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTAS 1109
+ L Y FR+ VN G S P Q + + ++ P + + +
Sbjct: 18854 --LEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKA 18911
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
L + ++ + G P++ + + + G+TL + V T+ L
Sbjct: 18912 REQLKI------DVPFKGRPQAT---VNWRKD---GQTLKETTRVNVSSSKTVTSLSIKE 18959
Query: 1170 EYRVQVQAF-----NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVP 1224
+ V + N+ GS T++ R P GP + ++ S+ + W+ P
Sbjct: 18960 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP--GPIRIDEVSC--DSITISWNP-P 19014
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV--EGNSSRSAQLTGLGKYVLYEVQVLAFTRI 1282
E D + Y V KE S T W + + + S ++ L Y+ +V A R
Sbjct: 19015 EYDGGCQISNYIVEKKETTSTT----WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19070
Query: 1283 GDGSPSHPP-ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL 1340
G S S ++ PGPP +++ + WQ P G ++ Y + ++
Sbjct: 19071 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19130
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + ++L Q +GL +Y +R+ A+ G G+ +++ RD
Sbjct: 19131 RSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPC 19188
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP +P V ++ +SV L W +P DG + + Y ++ RELP GRW L + +
Sbjct: 19189 DPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW-LKCNYTNIQET 19245
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
F V L Y+FRV A N SE SES + D P + + ++
Sbjct: 19246 YFEVTELTEDQRYEFRVFARN--AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIV 19303
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
++ KIN + G R ++ G + + ++ ++++ R
Sbjct: 19304 VKAGEVL--KINADIAG---RPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRR 19358
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1639
QY L N + ++ GP + P E+ +G TA +
Sbjct: 19359 DTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEI----------------NGLTAEK 19402
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
++W P D DI Y + + + +L + L S K+ L Y+
Sbjct: 19403 CSLSWGRPQEDG-GADIDYYIVE--KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFR 19459
Query: 1700 VAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEG 1756
V N G G S + PS P+S++ + +T S+ + W P+ G + G
Sbjct: 19460 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19519
Query: 1757 YRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT---FTYGPEIE 1813
Y + + + + V V+ K L +K L EG Y +R+ A+ + E
Sbjct: 19520 YIIERREKNSL----RWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETS 19575
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDI 1871
+ P PP P IV + I I W G PIT Y +E + SD+ W
Sbjct: 19576 PLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKT 19635
Query: 1872 LIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS--QSVPAQKANPFYE 1928
I+ + + YT S L G Y FRV +VN G PS S Q ++ P ++
Sbjct: 19636 SIQSL--RGTEYTISG--LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD 19690
Score = 211 bits (538), Expect = 5e-54
Identities = 373/1635 (22%), Positives = 612/1635 (37%), Gaps = 185/1635 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQ-----TSTYLAVTSIAPNITRGPLDS---- 411
+D ++ L DT F+ A+NAAG + T AP + LD+
Sbjct: 22500 SDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAP--PKAELDARLHG 22557
Query: 412 ---TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHIS 468
T+ G +VL G P P I W KG++ L ++T + + +I S
Sbjct: 22558 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG-KRATAVIKFCDRS 22616
Query: 469 DAGTYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGT--QASMVCGVT 520
D+G YT N+ G S + V + +++ Q++ + + Q +T
Sbjct: 22617 DSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEIT 22676
Query: 521 H---DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG-- 575
H + R T R W T S+ RL +N Y RV +
Sbjct: 22677 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNE-------------YIFRVRAVNKY 22723
Query: 576 --GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEM 629
G S + R +P P P + E I + WTKP DG + + Y+++
Sbjct: 22724 GPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH--IIIQWTKPESDGGNEISNYLVDK 22781
Query: 630 SENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE 688
E + WT + T + V L+ YQFR+ AVN G + S+ + +S E
Sbjct: 22782 REKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP 22841
Query: 689 PPT-APPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
T PP T SI + W P I+ GY++ Y+ T+A
Sbjct: 22842 SYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIV-GYVLEMQEKDTDQWYRVH--TNA 22898
Query: 748 DVNN--LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNS 805
+ N + DL + Y VAA N G+ YS + E +P + + +
Sbjct: 22899 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 22958
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
TIR A ++ + +I W + + + S+ + + K
Sbjct: 22959 VTIRA--GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-----VDKVN 23011
Query: 866 EYFTSVLCFTTPGD-GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y G +S LV+ + D PGP + E+ S+ ++W+ P G
Sbjct: 23012 RYDAGKYTIEAENQSGKKSATVLVKVY-DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23070
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + E + + TL YR++GL T Y V G G+ T
Sbjct: 23071 PVNNYIVEKREAAMRAFKTVTTKCSKTL-YRISGLVEGTMYYFRVLPENIYGIGE-PCET 23128
Query: 984 ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEA-QVGVVGEGEEW 1041
+ + E+P P L + ++ +VTL + +P YDG + ++ +++EA + G E W
Sbjct: 23129 SDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT----ERW 23184
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQTLQAPPDMA 1099
+ + L +P V LN Y FR+R N G S P + + +Q L+ P +
Sbjct: 23185 MKVVTL--KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTID 23242
Query: 1100 PANVSLRTAS-------ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS---DGHGKTLS 1149
+ + +T E + + P P + G K++ S + H K
Sbjct: 23243 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWF----FAGSKLRESERVTVETHTKVAK 23298
Query: 1150 HVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
+ R+ TI D E+T ++ N G+ + V+ + P +GP + +
Sbjct: 23299 LTI-----RETTIRDTGEYT-----LELKNVTGTTSETIKVIILDKPG-PPTGPIKIDEI 23347
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGK 1268
TS + + W E PE D + GY V E+ +P + V + +RS + T L +
Sbjct: 23348 DATS--ITISW-EPPELDGGAPLSGYVV---EQRDAHRPGWLPVSESVTRSTFKFTRLTE 23401
Query: 1269 YVLYEVQVLAFTRIGDGSPSHPPILE-RTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAP 1327
Y +V A R G GS ++E R+ +PGPP + +V + L W PP
Sbjct: 23402 GNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23461
Query: 1328 NGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA 1387
G + I R V + + +Y +TGL Y R+TA +G G+ +
Sbjct: 23462 GGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPS 23521
Query: 1388 EAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPS 1444
+V + P P P V D SV L+W P +G S V Y I+ +++
Sbjct: 23522 RPSKPIVAMDPIAPPGKPQNPRV--TDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ 23579
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEA 1504
W + + + + + L Y+FRV A N G E P E
Sbjct: 23580 HEWTKCNTTPT-KIREYTLTHLPQGAEYRFRVLACNAGGPGE--------------PAEV 23624
Query: 1505 PTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-----FTLRGINN 1559
P + VT ++ + D+ RY+E ++ G ++G
Sbjct: 23625 PGTVKVTE------MLEYPDYELDE----------RYQEGIFVRQGGVIRLTIPIKGKPF 23668
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
P W + S R + S T EL R Y+ V E + V++
Sbjct: 23669 PICKWTKEGQDISKRAMIATSETHTELVIKEADRG---DSGTYDLVLENKCG-KKAVYIK 23724
Query: 1620 EAV---PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG---NLTE 1673
V P + + + V+W PP D DI GY + E + +
Sbjct: 23725 VRVIGSPNSPEGPLEYDDIQVRSVRVSWR-PPADDGGADILGYILERREVPKAAWYTIDS 23783
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQAAPSAPSS- 1729
RV+ S+ +K L Y V+A N G P +T P PS+
Sbjct: 23784 RVR-----GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP 23838
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ ++T +SV++SW P+ G + GY + + S K V + + V
Sbjct: 23839 PEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETS----TDKWVRHNKTQITTTMYTV 23894
Query: 1789 KDLAEGVTYRFRIRAKT----FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHW 1844
L Y+FRI A+ P E V P + P + I+ ++ + W
Sbjct: 23895 TGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQW 23954
Query: 1845 SSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAV 1903
+ G I Y +E R S + W K + + F++ L Y+FRV A
Sbjct: 23955 EKPECDGGKEILGYWVEYRQSGDSAWK---KSNKERIKDKQFTIGGLLEATEYEFRVFAE 24011
Query: 1904 NDYGFGTPSSPSQSV 1918
N+ G P + S+
Sbjct: 24012 NETGLSRPRRTAMSI 24026
Score = 211 bits (537), Expect = 6e-54
Identities = 408/1878 (21%), Positives = 683/1878 (36%), Gaps = 218/1878 (11%)
Query: 136 RIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGD 192
R+ P+P +TW ++G+ + R+ + + L I V D G+Y + A KN
Sbjct: 11434 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISA---KNSS 11490
Query: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKL 247
+ V + GP + T + T + G SE+T V +P K
Sbjct: 11491 GHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQK- 11549
Query: 248 HIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP 307
W S SD +RL N ++ Y+ A + P++ + + P
Sbjct: 11550 --GW-------SIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINP 11600
Query: 308 PQFVKEPER-HITAEMEKVVDIPCQAKGVP--PPSITWYKDAAVVEVEKLTRFRQRN--D 362
EPE HI + + V + + P+++++ + + + R + + +
Sbjct: 11601 IDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKE 11660
Query: 363 GGLQISGLVPDDTGMFQCFARNAAGE---VQTSTYLAVTSIAPNITRGPLDS--TVIDGM 417
+ V + F+ +N GE V+T + + + L TV G
Sbjct: 11661 THYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11720
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRF---TPLESGSLLISPTHISDAGTYT 474
++ L G P P + W K + A+ + PR T +S ++ SD G Y
Sbjct: 11721 TIRLEAGVRGKPFPEVAWTKDKD--ATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11778
Query: 475 CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPR---------- 524
ATN+ G A A + V + KP +++ +S C V DP
Sbjct: 11779 VTATNTAGSFVAYATVNV-----LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQN 11833
Query: 525 ------VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGND 578
T R +W AT+ T RL IGT +
Sbjct: 11834 YILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGT-------GPPTE 11886
Query: 579 SRSAHLRVR-QLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP- 635
S+ + + P P+ P T V + + + W P +DG + Y LE E ++
Sbjct: 11887 SKPVIAKTKYDKPGRPDPPEVT--KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 11944
Query: 636 WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--PEEPPTAP 693
W + S P+ + V+ L+P YQFR+ A N++G G+ S + V P EPP P
Sbjct: 11945 WVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP-GP 12002
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII---------------RYCLAGLPVG 738
P N T SI + W P I+ GY++ + C A +
Sbjct: 12003 PTNFRVVDTTKHSITLGWGKPVYDGGAPII-GYVVEMRPKIADASPDEGWKRCNAAAQLV 12061
Query: 739 YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV 798
+ +T D N YE V A N G+G +++ E ++ + P +
Sbjct: 12062 RKEFTVTSLDENQ----------EYEFRVCAQNQVGIG-RPAELKE-AIKPKEILEPPEI 12109
Query: 799 HAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFV 858
+A+ + P F + + W + V R D +
Sbjct: 12110 DLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNV----VRKGQVDLVDTMAF 12165
Query: 859 SGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP 918
+ T + T + D PGPV L S++ TS VSW P
Sbjct: 12166 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPP 12225
Query: 919 GEKNGI-LTGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
G +T Y + E +R T + VT + + + VT L Y V A+ G
Sbjct: 12226 ENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS--FHVTNLVPGNEYYFRVTAVNEYGP 12283
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLV--EAQ 1031
G + + + P P PP L ++ + S TL + P DG I ++ +
Sbjct: 12284 GVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREE 12343
Query: 1032 VGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS---RK 1088
E+ ++ L S+ V L Y FR+ N VG S P +
Sbjct: 12344 EQPADRWTEYSVVKDL-------SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12396
Query: 1089 IQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
+ L P + P ++++ + + E G P K+ + + T
Sbjct: 12397 KEQLLPPKILMPEQITIKAGKKLRI--------EAHVYGKPHPT---CKWKKGEDEVVTS 12445
Query: 1149 SHVVQDRVERD--YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNV 1206
SH+ + + I+D+ + A N+ G+ VV P P ++
Sbjct: 12446 SHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG-PPQPPFDI 12504
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL-----VEGNSSRSA 1261
S + + S+ W +P D + Y V + D W+ V S R
Sbjct: 12505 SDIDADACSL--SW-HIPLEDGGSNITNYIV----EKCDVSRGDWVTALASVTKTSCRVG 12557
Query: 1262 QLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLI 1320
+L +Y+ +V A R G P + P ++ + VP P +V + +
Sbjct: 12558 KLIPGQEYIF---RVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVA 12614
Query: 1321 WQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
W P + G I+ Y I + + + L S +Y GL Y FRI A
Sbjct: 12615 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRST-EYPCAGLVEGLEYSFRIYALN 12673
Query: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQ 1438
+ G ++ T R PP +P V DV +V L W P DG S + Y ++
Sbjct: 12674 KAGSSPPSKPTEYVT-ARMPVDPPGKPEV--IDVTKSTVSLIWARPKHDGGSKIIGYFVE 12730
Query: 1439 TRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTL 1497
+LP +W ++A + L+ Y+FR A + S SE S+ +T L
Sbjct: 12731 ACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL 12790
Query: 1498 QAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
+V P SV ++ + N L T+ G
Sbjct: 12791 AE---------NVPPRIDLSVAMKSLLTVKAGTNVCL----------------DATVFGK 12825
Query: 1558 NNPGATWAE----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPP 1613
P +W + L ++ + +L EL ++N+ + ++ N+ G ++
Sbjct: 12826 PMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 12885
Query: 1614 QEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE 1673
+V P +V ++ + + ++WE PPL+ +I Y + E R N +
Sbjct: 12886 LKVL----DKPGPPASVKINKMYSDRAMLSWE-PPLEDGGSEITNYIVDKRETSRPNWAQ 12940
Query: 1674 RVKTLFLAENSVKLKNLTGYTAYMVSVAAFN--AAGDGPRSTPTQGQTQQAAPSAPSSVK 1731
T+ + SV+ K + G+ Y + A N GD + P + P
Sbjct: 12941 VSATVPITSCSVE-KLIEGH-EYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 12998
Query: 1732 FSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD 1790
S +T + VSW+ P G + GY L V+ V+ K LK
Sbjct: 12999 ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VNRKPIIERTLKATG 13054
Query: 1791 LAEGVTYRFRIRAKTFTYGPEIEANVTTG----PGEGAPGPPGVPIIVRYS-SAIAIHWS 1845
L EG Y FR+ A GP ++ + + PGPP P + + S++++ W
Sbjct: 13055 LQEGTEYEFRVTAIN-KAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW- 13112
Query: 1846 SGDP---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
G P G PI Y++E + +D W + ++P+ + F + L Y FRV A
Sbjct: 13113 -GKPAYDGGSPIIGYLVEVKRADSDNW--VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYA 13169
Query: 1903 VNDYGFGTPSS-PSQSVP 1919
VN G+ PS P + P
Sbjct: 13170 VNKIGYSDPSDVPDKHYP 13187
Score = 211 bits (537), Expect = 6e-54
Identities = 342/1451 (23%), Positives = 555/1451 (38%), Gaps = 168/1451 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W K G + +I S L I D G YT + G + V +
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 13975
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAP-WTVLLASVDPKA 647
P P PV +S V LTWT P DG SP+ YILE E + WTV+ S D ++
Sbjct: 13976 P-GPPGPVE-ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVV--SEDIQS 14031
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
L+ Y FR+ AVN GKG+ + + P PP+ S T +
Sbjct: 14032 CRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTA 14091
Query: 708 MIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKN-ITDADVNNLLLEDLIIWTNYEIE 766
+ W+ P + + I ++ R L K ++D L++ + YE
Sbjct: 14092 TVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQE---GSTYEFR 14148
Query: 767 VAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824
V+A N AG+G S ++ P PP N H T + W P +
Sbjct: 14149 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH------YD 14202
Query: 825 QGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG--FVSGLKKFTEYFTSVLCFTTPGDGPR 882
G ++ + E ++ + ++ + V L+ +Y + G G
Sbjct: 14203 GGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEP 14262
Query: 883 STPQLVRTHEDVPGPVGHLSFSEILDT-------SLKVSWQEPGEKNGILTGYRISWEEY 935
+ V E P L +E+ T S+++ G +T + +
Sbjct: 14263 AVIPDVEIVEREMAPDFELD-AELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK 14321
Query: 936 NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGP 995
NR N T + + T TIE A K G V+ + + PGP
Sbjct: 14322 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPA--GKKSGFVNVRVLDT------PGP 14373
Query: 996 PTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDAR 1054
NL ++I SVTL + P DG + I+ ++VE + + +
Sbjct: 14374 VLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS------YSTATTKCHKC 14427
Query: 1055 SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLW 1114
+ +V L+ Y FR+ N G P++ + ++ +AP P ++++ +++++
Sbjct: 14428 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSP--PDSLNIMDITKSTVS 14485
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQ 1174
L W P+ +++G + GY I+ R T V+ + + +L E EY Q
Sbjct: 14486 LAW---PKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL---ECVVRNLTEGEEYTFQ 14539
Query: 1175 VQAFNAIG-SGPW-SQTVVGRTRESVPS---SGPTNVSALATTSSSMLVRWSEVPEADRN 1229
V A N+ G S P S+ V+ + + +P G +A ++ V E+P R
Sbjct: 14540 VMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV---EIPVLGRP 14596
Query: 1230 GLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFT------RIG 1283
+ +K K + V ++ ++ + + + V + T +G
Sbjct: 14597 KPTVTWK-----KGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVG 14651
Query: 1284 DGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342
D ++ + D+PGPP G I F EV + V W PP G+ ++ + T
Sbjct: 14652 D-------VITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 14704
Query: 1343 TTANTATVEVLAPSARQ-YTATGLKPESVYLFRITAQTRKGWGEA-AEALVVTTEKRDRP 1400
+ T VE+ R Y AT L Y FR+ AQ R G G A +V P
Sbjct: 14705 DS--TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVP 14762
Query: 1401 QPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVSHNA 1458
PP P V V S+ +SW EP SDG SP+ Y ++ +E W + A V N
Sbjct: 14763 GPPGTPQVTA--VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 14820
Query: 1459 --SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTT 1515
SS + D + +Y+FRV A N G S+ S+ SE + L P P L++T HT
Sbjct: 14821 FKSSGLTDGI----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTV 14876
Query: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
T ++W P + G GF+I + + + P W + N
Sbjct: 14877 T---LKWAKP---EYTG---GFKIT----------SYIVEKRDLPNGRWLKA-------N 14910
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGPSSPPQEVFVGEAVPTAAPR----- 1628
S ++ + L + YE R+ NA G PS P + + V AP+
Sbjct: 14911 FSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDV 14968
Query: 1629 ----NVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
V++ A +L DV+ PPP + D + G +K +
Sbjct: 14969 KFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD--------GKELEGTAKLEIKIADFST 15020
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
N V K+ T + ++ A N G + + P P +V +E+T+ +
Sbjct: 15021 NLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAV--TEVTSEKCVL 15077
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLW-LKVKDLAEGVTYRFRI 1801
SW P G + +V + S++ +V + LKV L +G Y FR+
Sbjct: 15078 SWFPPLDDGGAKIDHYIVQKR-----ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRV 15132
Query: 1802 RA-KTFTYGPEIEANVTTGPGE-GAPGPPGVPIIVRYSS-AIAIHWSSGDP-GKGPITRY 1857
A + G +E+ G P PP P + + ++ + W D G I Y
Sbjct: 15133 MAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15192
Query: 1858 VIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQS 1917
++E R W IK K ++ + + L G Y+FR++A N G PS S
Sbjct: 15193 IVERRDKAGQRW---IKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-- 15247
Query: 1918 VPAQKANPFYE 1928
PFY+
Sbjct: 15248 -------PFYK 15251
Score = 211 bits (537), Expect = 6e-54
Identities = 438/1934 (22%), Positives = 700/1934 (36%), Gaps = 355/1934 (18%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY----YVQAVNDKNGDNKTS 196
P P+VTW +D + + I T TL+I+ P+ RY +V + + G K S
Sbjct: 14307 PAPEVTWTKDNINLKNRANIENTESFTLLII----PECNRYDTGKFVMTIENPAG--KKS 14360
Query: 197 QPITLTVENVGGPADPIAPTIIIPPKNT-----SVVAGTSEVTLECVANARPLIKLHIIW 251
+ + V + GP + PT I T ++ G S +T +I+
Sbjct: 14361 GFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT------------NYIVE 14408
Query: 252 KKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFV 311
K++ S + TG G CE R + G EP V
Sbjct: 14409 KREATRKSYSTATTKCHKCTYKVTGLSEG---CEYFFRVMAENEYGIGEPTETTEP---V 14462
Query: 312 KEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLV 371
K E + ++DI S+ W K ++DGG +I+G V
Sbjct: 14463 KASEAPSPPDSLNIMDITKST-----VSLAWPK--------------PKHDGGSKITGYV 14503
Query: 372 PD-------------DTGMFQCFARN-AAGEVQTSTYLAVTS------------------ 399
+ +C RN GE T +AV S
Sbjct: 14504 IEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14563
Query: 400 IAPNI-TRGPLDSTVI--DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLE 456
+ P + RG VI G ++ + G P+P +TW+KG++IL Q F
Sbjct: 14564 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK--QTQRVNFETTA 14621
Query: 457 SGSLL-ISPTHISDAGTYTCLATNSRG----------------------VDEASADLVVW 493
+ ++L I+ SD+G Y A N G DE S+D V +
Sbjct: 14622 TSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 14681
Query: 494 ARTRITKPPQDQS-------VIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
+ PP++ V++ Q V V IR ++ T G E R+
Sbjct: 14682 S----WDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-IRTTYKATRLTTGLEYQFRV 14736
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
+ + T + + Y +V P P P T V +
Sbjct: 14737 KAQNRYGVGPGITSACIVANYPFKV------------------PGPPGTPQVT--AVTKD 14776
Query: 607 AINLTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFR 664
++ ++W +P DG SP++ Y +E E N W + ++ P GL +Y+FR
Sbjct: 14777 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP-GNIFKSSGLTDGIAYEFR 14835
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-L 723
+ A N GK + SK +E + + P PP + T ++ ++W P + G +
Sbjct: 14836 VIAENMAGKSKPSKPSEPMLALD--PIDPPGKPVPLNITRHTVTLKWAKP--EYTGGFKI 14891
Query: 724 KGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782
YI+ LP G K N ++ N + L YE V A N+AG
Sbjct: 14892 TSYIVE--KRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG-------- 14941
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM 842
PP +E +++ T R AP + L A E + E
Sbjct: 14942 --------AISPP----SEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 14989
Query: 843 VTARPNFQDSIHVGFVSGLK----KFTEYFTSVL----------CFTTPGDGPRSTPQLV 888
P + S + G K ++ T+++ +T P + +
Sbjct: 14990 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHI 15049
Query: 889 RTHE--DVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTH 944
+ D PG P G L+ +E+ +SW P + G + Y + E +R
Sbjct: 15050 FNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA 15109
Query: 945 YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISN 1003
VT + +VT L Y V A+ G G+ + + + + P P PP N ++
Sbjct: 15110 SEVQVT-KLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTT 15168
Query: 1004 IGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN 1062
I S+ + + P DG + I ++VE + G+ W+ ++ D R +V L
Sbjct: 15169 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKA---GQRWIKCNK-KTLTDLR-YKVSGLT 15223
Query: 1063 PFTCYSFRMRQVNIVGTSPPSQPS---RKIQTLQAPPDMAPANVSLRTASETSLWLRW-M 1118
Y FR+ N G S PS S + T+ P P N + S +S+ + W
Sbjct: 15224 EGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG--PPGNPRVLDTSRSSISIAWNK 15281
Query: 1119 PLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAF 1178
P+ Y+G E GY ++ + + + YTI L E EY++++ A
Sbjct: 15282 PI----YDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAM 15337
Query: 1179 NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR---------------WSEV 1223
N+ G G +V T ++ P + A + +R EV
Sbjct: 15338 NSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEV 15395
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
A +G + + K T L+ GN +R GKY+L +
Sbjct: 15396 KWARDHG-----ESLDKASIESTSSYTLLIVGNVNRFDS----GKYIL---------TVE 15437
Query: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTT 1343
+ S S + + D PGPP + EV TSV L W PP G + I + +T
Sbjct: 15438 NSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 15497
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPP 1403
+TV + L+ Y FR+ A+ G G AE + + +RP PP
Sbjct: 15498 RKAYSTVATNCHKT-SWKVDQLQEGCSYYFRVLAENEYGIGLPAET-AESVKASERPLPP 15555
Query: 1404 SRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462
+ + DV SV LSWE P DG S + Y ++ + S +WA + +
Sbjct: 15556 GK--ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA---TCATVKVTEAT 15610
Query: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRW 1522
+ L Y FRV A N+ G S+ P LSV P ++I
Sbjct: 15611 ITGLIQGEEYSFRVSAQNEKGISD------------------PRQLSV-PVIAKDLVI-- 15649
Query: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATW------AELTSM 1570
PPA F++ + + L G L+ G P TW + T+
Sbjct: 15650 -PPA----------FKLLFN--TFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTR 15696
Query: 1571 YSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV 1630
+ + SL + Y ++++ N+ GE + V PT V
Sbjct: 15697 VNAESTENNSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIVLDKPGPPTGP---V 15751
Query: 1631 VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNL 1690
+ TA + ++W PP D I Y + + T ++ + +A ++K L
Sbjct: 15752 KMDEVTADSITLSWGPPKYDG-GSSINNYIVE--KRDTSTTTWQIVSATVARTTIKACRL 15808
Query: 1691 TGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
Y +AA N G S PT Q P P + + + S+ V W
Sbjct: 15809 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWN--- 15865
Query: 1749 FPNGILEGYRLVYEPCSPVDGVSKIVTVDV---KGNSPLWLKVK------------DLAE 1793
EP S DG S+++ + + NS LW+K+ L E
Sbjct: 15866 -------------EPIS--DGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 15910
Query: 1794 GVTYRFRIRAKTFT----YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD- 1848
GV Y FR+ A+ E V P + PG P I+ R +++ + W
Sbjct: 15911 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCD-PPGRPEAIIVTR--NSVTLQWKKPTY 15967
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG- 1907
G IT Y++E + EG W +K + F + L Y+FRVIA N G
Sbjct: 15968 DGGSKITGYIVEKKELPEGRW---MKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 16024
Query: 1908 FGTPSSPSQSVPAQ 1921
F PS + ++ A+
Sbjct: 16025 FSEPSESTGAITAR 16038
Score = 210 bits (535), Expect = 1e-53
Identities = 345/1488 (23%), Positives = 556/1488 (37%), Gaps = 155/1488 (10%)
Query: 506 SVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LDRNGSLHISQTWSGDI 564
+V GT+ + VT P I W K L + I + + ++ I + D
Sbjct: 7204 TVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7261
Query: 565 GTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLI 623
GTY ++ G + + V P P ++ V + LTW P D G S +
Sbjct: 7262 GTYIIEAVNVCGRATAVVEVNVLDKPGPPA--AFDITDVTNESCLLTWNPPRDDGGSKIT 7319
Query: 624 RYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
Y++E ++ W L ++V K T+ L+P + Y FR+ A N G G+ + +
Sbjct: 7320 NYVVERRATDSEVWHKLSSTV--KDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 7377
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
+ + P PP + S T ++ + W P + + I GY + +
Sbjct: 7378 TAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT-GYWVERLDPDTDKWVRCN 7436
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGV--PTVPPGNVHA 800
+ D ++ L Y V A N AG G S ++ P PPG
Sbjct: 7437 KMPVKDTT-YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTV 7495
Query: 801 EATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ T++R W P I + Y + + +E V + P Q + G
Sbjct: 7496 KDVGKTSVRLNWTKPEHDGGAKI-ESYVIEMLKTGTDEWVRVAEGVPTTQH-----LLPG 7549
Query: 861 LKKFTEYFTSVLCFTTPGDGPRSTPQ---LVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G+ S P L R P P L I + + W
Sbjct: 7550 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTV 7609
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +T Y + + R + T + VT LT + Y VAA + GQ
Sbjct: 7610 PEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDT-KCTVTPLTEGSLYVFRVAAENAIGQ 7668
Query: 977 GQVSA--STISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVG 1033
+ ++ + PGPP L + ++ R V L++ P DG I R+++E +
Sbjct: 7669 SDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKER 7728
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
+ G W+ + + PD + V D+ T F++R N G PS+P+ +I +++
Sbjct: 7729 L---GTRWVKAGKTAG-PDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT-EILSIE 7782
Query: 1094 AP--PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKI--------KYSRSDG 1143
P P P ++ + A + + W P E NG +GY + K+ R +
Sbjct: 7783 DPTSPPSPPLDLHVTDAGRKHIAIAWKP---PEKNGGSPIIGYHVEMCPVGTEKWMRVNS 7839
Query: 1144 HG-KTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG---SGPWSQTVVGRTRESVP 1199
K L V++ V D EY ++V+A NAIG S+ VV + + P
Sbjct: 7840 RPIKDLKFKVEEGVVPD---------KEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKP 7890
Query: 1200 SSG--PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
+ ++ + S+ V + VP V +K + K SD L N
Sbjct: 7891 TIDLETHDIIVIEGEKLSIPVPFRAVPVPT----VSWHKDGKEVKASDR-----LTMKND 7941
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFT---RIGDGSPSHPPILERTLDDVPGPPMGILFPEVRT 1314
SA L + K V + + T ++G + S + + +PGP I ++
Sbjct: 7942 HISAHLE-VPKSVRADAGIYTITLENKLGSATAS----INVKVIGLPGPCKDIKASDITK 7996
Query: 1315 TSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFR 1374
+S +L W+PP G + + + R V + + +T L P Y FR
Sbjct: 7997 SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFR 8055
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSWEPGS-DGLSPV 1432
+ A + G GE E L +D QPP P+ V+ + A ++ ++W+P DG S +
Sbjct: 8056 VKAVNKVGGGEYIE-LKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8114
Query: 1433 RYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE 1492
Y I+ RW + + ++ L+ Y+FRV+A N G SE S +
Sbjct: 8115 MGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATP 8173
Query: 1493 SLTTLQAAPDEAPTIL-------------------SVTPHTTTSVLIRWQP------PAE 1527
T P +AP ++ S +P+ T I W P E
Sbjct: 8174 P--TKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPT----ITWIKDENVIVPEE 8227
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
K L +R R+ + F L LT S+ N + D
Sbjct: 8228 IKKRAAPL---VRRRKGEVQEEEPFVL-----------PLTQRLSIDNSKKGESQLRVRD 8273
Query: 1588 NLNK-HRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEP 1646
+L H Y I++ + + + P + V P N V T + WEP
Sbjct: 8274 SLRPDHGLYMIKVENDHGIAKAPCT------VSVLDTPGPPINFVFEDIRKTSVLCKWEP 8327
Query: 1647 PPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAA 1706
P LD +I Y + + + + V T L + L Y+ V A N
Sbjct: 8328 P-LDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8386
Query: 1707 GDGPR--STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
G GP S P + P AP ++T+ S+ V W P+ + GY L
Sbjct: 8387 GPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREV 8446
Query: 1765 SPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT----YGPEIEANVTT 1818
+ V+K + +K N V L EG+TY FR+ A+ + P +
Sbjct: 8447 NSTHWSRVNKSLLNALKAN------VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAH 8500
Query: 1819 GPGEGAPGPPGVPIIVRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIP 1877
P PGPP + S+ I + W G G I Y ++ + W + +
Sbjct: 8501 DP-ISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI 8559
Query: 1878 KEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
K V YT ++ G Y RV AVN G G P A+ P
Sbjct: 8560 K-VRQYTVKE--IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP 8604
Score = 207 bits (527), Expect = 9e-53
Identities = 337/1448 (23%), Positives = 550/1448 (37%), Gaps = 155/1448 (10%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISAGGNDSRS 581
P+ T+ W KDG TL + + + SL I + D+GTY V ++ G+ +
Sbjct: 18925 PQATVN--WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 18982
Query: 582 AHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVL 639
+ V P P P+ + V +I ++W P +DG + YI+E E + W ++
Sbjct: 18983 ITIIVLDRP-GPPGPIR-IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19040
Query: 640 LASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIA 699
+V TS+ + L YQFR+CA N GK +S+ + V+ P PP
Sbjct: 19041 SQAV--ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV 19098
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
T ++++ WQ P + ++ GY + Y + + I AD + + L
Sbjct: 19099 VHATKSTMLVTWQVPVNDGGSRVI-GYHLEYKERSSILWSKANKILIADTQ-MKVSGLDE 19156
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
YE V A N AG+G SK E P PPG ++ W+ P
Sbjct: 19157 GLMYEYRVYAENIAGIGK-CSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPH--- 19212
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEY----FTSVLCF 874
+ G K+ + E+ E + N+ + F V+ L + Y F
Sbjct: 19213 ---YDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAAD 19269
Query: 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS----LKVSWQEPGEKNGILTGYRI 930
+ + P +V+ + P + + F +++ LK++ G +++ +
Sbjct: 19270 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19329
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPP 990
E R T + + L + Y + + + V+ +
Sbjct: 19330 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK---- 19385
Query: 991 ELPGPPTN-LGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP L I+ + +L + RP DG I ++VE + W +
Sbjct: 19386 --PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET---SHLAWTICE--- 19437
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP--SQPSRKIQTLQAPPDMAPANVSLR 1106
E S +V L Y FR+ VN G P S + + P P ++ +
Sbjct: 19438 GELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEIT 19495
Query: 1107 TASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV-VQDRVERDYTIED- 1164
+ ++ S+ L W E +G E GY I+ + +L V V + D ++
Sbjct: 19496 SVTKESMTLCWS---RPESDGGSEISGYIIERREKN----SLRWVRVNKKPVYDLRVKST 19548
Query: 1165 -LEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESV----PSSGPTNVSALATTSSSMLV 1218
L E EY +V A NA G S P + + R + V P S P V + TT + +
Sbjct: 19549 GLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTT---ITI 19605
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLT--GLGKYVLYEVQV 1276
W + P D + GY V YK+ D DT W S R + T GL Y +V
Sbjct: 19606 AWVK-PLFDGGAPITGYTVEYKKSD-DTD---WKTSIQSLRGTEYTISGLTTGAEYVFRV 19660
Query: 1277 LAFTRIGDGSPSH---PPILERTLDDVPGPPMGILFPEVRTTSV---RLIWQPPAAPNGI 1330
+ ++G PS P I + ++ P+ + E+R T + + G
Sbjct: 19661 KSVNKVGASDPSDSSDPQIAKEREEE----PLFDIDSEMRKTLIVKAGASFTMTVPFRGR 19716
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ + + +T A V+ S T + +T Q +A +L
Sbjct: 19717 PVPNVLWSKPDTDLRTRAYVDT-TDSRTSLTIENANRNDSGKYTLTIQNVL----SAASL 19771
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWAL 1449
+ + D P PP+ VQ DV S +LSW+ P +DG +PV+ Y I+ RE W
Sbjct: 19772 TLVVKVLDTPGPPTNITVQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWV- 19828
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
S + + N S+ V L+ Y FRV N+ G +E E + + P L
Sbjct: 19829 -SVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKP--SPPEKLG 19885
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + SV + W P D G RI + + + + W +
Sbjct: 19886 VTSISKDSVSLTWLKPEHDG------GSRIVH----------YVVEALEKGQKNWVKCAV 19929
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------P 1623
S T + + L ++ Y R+ N G S P+E+ + + P
Sbjct: 19930 AKS---------THHVVSGLRENSEYFFRVFAENQAG---LSDPRELLLPVLIKEQLEPP 19977
Query: 1624 TAAPRN-----VVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
+N V V + ++D+ PL G + T R T
Sbjct: 19978 EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL--------KATMRFNTE 20029
Query: 1679 FLAEN-SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737
AEN ++ LK A + A N++G + P+ P V S++T
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP--VVISDITE 20087
Query: 1738 TSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVT 1796
SV + WE P++ G + Y L+ S TV + +KV L G
Sbjct: 20088 ESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV-----ARTMMKVMKLTTGEE 20142
Query: 1797 YRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKG 1852
Y+FRI+A+ F I+ A VT PGPP P + + +I + W G
Sbjct: 20143 YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGS 20202
Query: 1853 PITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ Y +E + + LW K + + + F + + G+ Y+FRV A N G G PS
Sbjct: 20203 AVVGYHLEMKDRNSILWQKANKLV---IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPS 20259
Query: 1913 SPSQSVPA 1920
PS+ V A
Sbjct: 20260 HPSEPVLA 20267
Score = 207 bits (526), Expect = 1e-52
Identities = 333/1443 (23%), Positives = 538/1443 (37%), Gaps = 164/1443 (11%)
Query: 531 WEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W DG+ + T+ H + D S L I D G Y V +A G+ + + HL V +
Sbjct: 11047 WTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDV 11106
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P+ L + ++W P D G SP+I YI+E + +++S K T
Sbjct: 11107 PGPPTGPINILDVTPEH-MTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 11164
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ + L Y FR+ A N +G G T V+ + P +PP + + T +
Sbjct: 11165 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT 11224
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVA 768
+ W P + I Y+ R + G V I D + L YE V
Sbjct: 11225 VSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADL---KFRVTGLYEGNTYEFRVF 11281
Query: 769 AYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG 826
A N AGL SS + P PP N + + T W P + G
Sbjct: 11282 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS------DGG 11335
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIH--VGFVSGLKKFTEYFTSVLCFTTPGDG-PRS 883
++ + E ++ T R N + I V GL + EY + G+G PR
Sbjct: 11336 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11395
Query: 884 TPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYR------ISWEEYNR 937
+ V + + H E+ T V G+ IL + I+W + +
Sbjct: 11396 LAESV-----IAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11450
Query: 938 TNTR-----VTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
R + LP V L+ + Y I + QG + + +
Sbjct: 11451 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVL------DR 11504
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
PGP NL ++N+ + T+ + P +G + I+ ++VE + + W ++ +++
Sbjct: 11505 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR---KPNQKGWSIV---ASDV 11558
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQ---PSRKIQTLQAPPDMAPANVSLRTA 1108
R ++ +L Y FR+ N VG P + P I + P + P N+ +
Sbjct: 11559 TKRLIKA-NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGE--PENLHIADK 11615
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLE 1166
+T ++L+W +Y+G ++ Y + + SD + ++ E Y ++
Sbjct: 11616 GKTFVYLKWR---RPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK---ETHYMVDRCV 11669
Query: 1167 EWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS-------SGPTNVSALATTSSSMLVR 1219
E Y +VQ N G W +T +E + SG V A T VR
Sbjct: 11670 ENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVR 11729
Query: 1220 WSEVPEA----DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQ 1275
PE D++ L K +F L + S GKYV
Sbjct: 11730 GKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDG------GKYV----- 11778
Query: 1276 VLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ 1335
V A G S + D PGP + +V + + W PP G +
Sbjct: 11779 VTATNTAG----SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 11834
Query: 1336 ITHRLNTTTA--NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VV 1392
I + T +T + VL P T T L + Y+FR+ A+ + G G E+ V+
Sbjct: 11835 ILEKCETKRMVWSTYSATVLTPGT---TVTRLIEGNEYIFRVRAENKIGTGPPTESKPVI 11891
Query: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWA-LH 1450
K D+P P P V + V + + W P DG + Y ++ +E S RW ++
Sbjct: 11892 AKTKYDKPGRPDPPEVTK--VSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN 11949
Query: 1451 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ-AAPDEAPTILS 1509
+++ V L P Y+FRVKA N+IG E S S + P PT
Sbjct: 11950 KSAIPERRMK--VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFR 12007
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
V T S+ + W P D ++G+ + R + + +P W +
Sbjct: 12008 VVDTTKHSITLGWGKPVYDG-GAPIIGYVVEMRPKIADA----------SPDEGWKRCNA 12056
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG------PSSPPQEVFVGEAVP 1623
+ ++ + +L++++ YE R+ N VG G + P+E+ +
Sbjct: 12057 AAQLVR------KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEID 12110
Query: 1624 TAAP--RNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL- 1678
A + V+V +L V P P + K+ R + V T+
Sbjct: 12111 LDASMRKLVIVRAGCPIRLFAIVRGRPAP------KVTWRKVGIDNVVRKGQVDLVDTMA 12164
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
FL + + Y+ +V+ A A R T P S +K S++T T
Sbjct: 12165 FLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDT--------PGPVSDLKVSDVTKT 12216
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYR 1798
S +VSW P+ G + +V E VT +VK S V +L G Y
Sbjct: 12217 SCHVSWAPPENDGGSQVTHYIV-EKREADRKTWSTVTPEVKKTS---FHVTNLVPGNEYY 12272
Query: 1799 FRIRAKTFTYGPEIEANV-----TTGPGEGAPGPPGVPIIVRYSSAIAIHW-----SSGD 1848
FR+ A YGP + +V + P P + + ++ + W G
Sbjct: 12273 FRVTAVN-EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGA 12331
Query: 1849 PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGF 1908
G IT Y E +P+D ++KD+ V+ LK G Y FRV A N G
Sbjct: 12332 KIDGYITSYREEEQPADRWTEYSVVKDLSLVVTG-------LKEGKKYKFRVAARNAVGV 12384
Query: 1909 GTP 1911
P
Sbjct: 12385 SLP 12387
Score = 204 bits (520), Expect = 6e-52
Identities = 375/1638 (22%), Positives = 639/1638 (39%), Gaps = 191/1638 (11%)
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAG---EVQTSTYLAVTS----IAPNITRGP--LDST 412
D +++GLV D F+ ARNAAG E ST A+T+ P I+ P D+
Sbjct: 15998 DTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTG-AITARDEVDPPRISMDPKYKDTI 16056
Query: 413 VID-GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
V+ G S + + G P P I W KG++ L S + +L + + SL + D+G
Sbjct: 16057 VVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAVRVDSG 16115
Query: 472 TYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQA---------------SMV 516
Y A N G + ++ V R PP+ VI G A S +
Sbjct: 16116 NYILKAKNVAGERSVTVNVKVLDR---PGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDI 16172
Query: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG- 575
+ R T R +W A + T S +++ G+ YT R+++
Sbjct: 16173 INYIVERRETSRLVWTVVDANVQTL-----------SCKVTKLLEGN--EYTFRIMAVNK 16219
Query: 576 ---GNDSRSAHLRVRQ---LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILE 628
G S + + +P AP+ P T TV + ++ + W +P DG S ++ Y+LE
Sbjct: 16220 YGVGEPLESEPVVAKNPFVVPDAPKAPEVT--TVTKDSMIVVWERPASDGGSEILGYVLE 16277
Query: 629 MSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT--ERVSL 685
+ WT + + + V GL+ Y+FR+ A N G + S + ++
Sbjct: 16278 KRDKEGIRWTRCHKRLIGE-LRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 16336
Query: 686 PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
P P PP N T S+ + W P + G ++GYI+ C +
Sbjct: 16337 PIYKP-GPPNNPKVIDITRSSVFLSWSKP--IYDGGCEIQGYIVEKCDVSVGEWTMCTPP 16393
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T + N+ +E L+ Y + A N AG+G ++ ++ P ++ E
Sbjct: 16394 TGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRK 16453
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLK 862
IR F+ + + W E + ++ +F + L
Sbjct: 16454 IINIRA--GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV-------LD 16504
Query: 863 KFTEYFTSVLCFTTP-GDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEK 921
Y + T G +S VR D P P +L +EI S+ ++W+ P
Sbjct: 16505 NVNRYDSGKYTLTLENSSGTKSAFVTVRV-LDTPSPPVNLKVTEITKDSVSITWEPPLLD 16563
Query: 922 NGI-LTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ 978
G + Y + E R + VT+ N +++ L +Y V A G G
Sbjct: 16564 GGSKIKNYIVEKREATRKSYAAVVTNCHKN---SWKIDQLQEGCSYYFRVTAENEYGIG- 16619
Query: 979 VSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+ A T E+P PP + + ++ SV+L + +P +DG + I +++VE Q
Sbjct: 16620 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ---AKH 16676
Query: 1038 GEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQ 1093
E+W S +S++ + +L Y FR+ VN G S P + I + L
Sbjct: 16677 SEKW------SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV 16730
Query: 1094 APPDMAPA--NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV 1151
PD+ PA + S++ + + E+ +G P+ I +++ K + +
Sbjct: 16731 IEPDVKPAFSSYSVQVGQDLKI--------EVPISGRPKPT---ITWTKDGLPLKQTTRI 16779
Query: 1152 -VQDRVE-RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
V D ++ +I++ + + + N +G S +V + P GP +
Sbjct: 16780 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD-PPKGPVKFDDV 16838
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW-LVEGNSSRSA-QLTGLG 1267
++ S+ + W+ P G + ++ K DT W +V +R+ ++T L
Sbjct: 16839 --SAESITLSWN--PPLYTGGCQITNYIVQKR---DTTTTVWDVVSATVARTTLKVTKLK 16891
Query: 1268 KYVLYEVQVLAFTRIGDG-SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAA 1326
Y+ ++ A R G + PI+ + PGPP + S+ + W P
Sbjct: 16892 TGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVN 16951
Query: 1327 PNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGE 1385
G ++ Y + + + T + + Q+ A L+ Y FR+ A+ G G+
Sbjct: 16952 NGGSPVIGYHLERKERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGK 17010
Query: 1386 AAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTREL 1442
A++ V + D P P MV++ + + L W +P DG S + Y ++ R+L
Sbjct: 17011 ASKNSECYVARDPCDPPGTPEPIMVKRNE-----ITLQWTKPVYDGGSMITGYIVEKRDL 17065
Query: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
P GRW + ++ + + F V L Y+FRV A N G S+ S+S + A +
Sbjct: 17066 PDGRW-MKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG--AISKPSDSTGPITAKDE 17122
Query: 1503 EAPTILSVTPHTTTSVLIRWQPP--AEDKINGILLGFRIRYRELLYEGLRG-FTLRGINN 1559
+S+ P ++++ E ++G L E LRG +
Sbjct: 17123 VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP--------TIEWLRGDKEIEESAR 17174
Query: 1560 PGATWAELTSMYSMRNLSRPSLTQYEL--DNLNKHRRYEIRMSVYNAVG--EGPSSPPQE 1615
+ ++ +++ R QY L N+ + + + + V + G EGP
Sbjct: 17175 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP------ 17228
Query: 1616 VFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERV 1675
V V G T+ + +TW PPL DI Y + E R L V
Sbjct: 17229 --------------VQVTGVTSEKCSLTWS-PPLQDGGSDISHYVVEKRETSR--LAWTV 17271
Query: 1676 KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFS 1733
+ NS+K+ L Y+ + A N G G S P + P P S++ +
Sbjct: 17272 VASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 17331
Query: 1734 ELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLA 1792
+ S+ V W P G + GY + S + + + + + + L L+V L
Sbjct: 17332 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGI----RWIKCNKRRITDLRLRVTGLT 17387
Query: 1793 EGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPP-GVPIIVRYSSAIAIHWSSGD 1848
E Y FR+ A+ G A V + PGPP I+ ++I + W G
Sbjct: 17388 EDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW--GK 17445
Query: 1849 P---GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
P G I YV+E +DE W I+ V+ + S L Y RV A+N
Sbjct: 17446 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISK--LTEHQEYKIRVCALNK 17503
Query: 1906 YGFGTPSS-PSQSVPAQK 1922
G G +S P P K
Sbjct: 17504 VGLGEATSVPGTVKPEDK 17521
Score = 202 bits (515), Expect = 2e-51
Identities = 431/1978 (21%), Positives = 725/1978 (36%), Gaps = 286/1978 (14%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGAL----------LQRQTEVQ--VAYMGSFEEGEK 120
E +Y +T L +R I RN +G + + R V V + + +G
Sbjct: 21413 ECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDG-- 21470
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT--LENTLVILSTVAPDA 178
+ GE+ I+A + P P+VTWF+DG +I + IT L +T + + D
Sbjct: 21471 -LIIKSGESLRIKA-LVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDH 21528
Query: 179 GRYYVQAVNDKNGDNKTSQPITL--TVENVGGPA-------------------DPIAPTI 217
Y + +G K + + T V GP D AP
Sbjct: 21529 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 21588
Query: 218 --IIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPT 275
II + TS +A + +C A + IKL +G +S N+ + P
Sbjct: 21589 HYIIEKRETSRLAWAL-IEDKCEAQSYTAIKLI-----NGNEYQFRVSAVNK-FGVGRPL 21641
Query: 276 GSDAGYYECEAVLRSSS---VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQA 332
SD + + + + PS + G +++ PE +E+++ + +
Sbjct: 21642 DSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA-----RPESDGGSEIQQYILERREK 21696
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
K S W K + + + TRF+ ++GL + F A NAAG S
Sbjct: 21697 K-----STRWVKVISKRPISE-TRFK--------VTGLTEGNEYEFHVMAENAAGVGPAS 21742
Query: 393 ------------------TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
T + VT + V DG ++
Sbjct: 21743 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21802
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGV-DEASADLVVW 493
W K + A V+ R+T ++ + + A N G D +
Sbjct: 21803 WHK---VNAEACVKT-RYT--------VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIK 21850
Query: 494 ARTRITKPPQD------QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIR 547
A R+T P D Q+ + AS+ + + R T +W K + L +
Sbjct: 21851 AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT 21910
Query: 548 LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRA 607
D +L + D G YT V + G+ S + ++V P P P+ T V R +
Sbjct: 21911 -DSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTP-GPPGPI-TFKDVTRGS 21967
Query: 608 INLTWTKPF-DGNSPLIRYILEMSE-NNAPWTVLLASVDPKATS--VTVKGLVPARSYQF 663
L W P DG + + Y++E E + W V + K T V L Y F
Sbjct: 21968 ATLMWDAPLLDGGARIHHYVVEKREASRRSWQV----ISEKCTRQIFKVNDLAEGVPYYF 22023
Query: 664 RLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI- 722
R+ AVN+ G G+ + E + E+P APP+ + + S ++ W P H G
Sbjct: 22024 RVSAVNEYGVGEPYEMPEPIVATEQP--APPRRLDVVDTSKSSAVLAWLKP--DHDGGSR 22079
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG----VY 778
+ GY++ G + + +E L+ T YE V A N AG +
Sbjct: 22080 ITGYLLEMRQKGSDFWVEAGHTKQL---TFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 22136
Query: 779 SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG-------YKLIA 831
SS + + P + P A+ T T T A SP I+ G +KL
Sbjct: 22137 SSVIIK-----EPQIEPT---ADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEE 22188
Query: 832 WEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH 891
++ + V++ T + ++ + YF ++ T G S +V
Sbjct: 22189 MRLKETDRVSITTTKDRTTLTVKDSMRGDSGR---YFLTLE--NTAGVKTFSVTVVVIGR 22243
Query: 892 EDVPGPV-GHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNV 949
PGPV G + S + S +SW EP + G +T Y + E T ++ +
Sbjct: 22244 ---PGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKR 22300
Query: 950 TLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNIGPRS 1008
T + +VT LT Y+ V++ G + + ++ I + P P PT + ++ +
Sbjct: 22301 T-QIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANA 22359
Query: 1009 VTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
+++++ P +DG + I + VE + E L + + + +V L Y
Sbjct: 22360 MSIRWEEPYHDGGSKIIGYWVEKK-----ERNTILWVKENKVPCLECNYKVTGLVEGLEY 22414
Query: 1068 SFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNG 1127
FR +N G S S+ SR I Q P D AP + + +++ L W Y+G
Sbjct: 22415 QFRTYALNAAGVSKASEASRPIMA-QNPVD-APGRPEVTDVTRSTVSLIWSA---PAYDG 22469
Query: 1128 NPESVGYKI--KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGP 1185
+ VGY I K G G+ L + +T+ L E Y +V A NA G
Sbjct: 22470 GSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG--- 22526
Query: 1186 WSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD 1245
V+ + ES + A + V + LVL V K
Sbjct: 22527 ----VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKP---- 22578
Query: 1246 TQPRFWLVEGNSSR------SAQLTGL--------------GKYVLYEVQVLAFTRIGDG 1285
+P+ +G+ S Q TG GKY L +
Sbjct: 22579 -EPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS-- 22635
Query: 1286 SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTA 1345
++ + LD PGP + V L W P G + + I R T+
Sbjct: 22636 ------VMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 22688
Query: 1346 NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEKRDRPQPPS 1404
N VE P+ Y T L + Y+FR+ A + G G E+ +V P PP
Sbjct: 22689 NWVIVEGECPTL-SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPG 22747
Query: 1405 RPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463
P ++ +++ W +P SDG + + Y + RE S RW + + V
Sbjct: 22748 IP--EEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKV 22805
Query: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA----PDEAPTILSVTPHTTTSVL 1519
L Y+FRV A N G+SE SE S ++ + + P AP ++ T H S+
Sbjct: 22806 TSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKH---SIS 22862
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
+ W P D I+ G+ L W + + ++RN
Sbjct: 22863 LAWTKPMYDGGTDIV----------------GYVLEMQEKDTDQWYRVHTNATIRN---- 22902
Query: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSS-------PPQEVFVGE-AVPTAAPRNVV 1631
T++ + +L ++Y R++ N G S P + + + + + + V
Sbjct: 22903 --TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVT 22960
Query: 1632 VHGATATQL--DVTWEPPPL---DSQNGDIQGYKIY-FWEAQRGNLTERVKTLFLAENSV 1685
+ + +L V+ PPP+ Q D+ I E+ + ++V + ++
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTI 23020
Query: 1686 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
+ +N +G + V V ++ G P SVK E++ SV ++WE
Sbjct: 23021 EAENQSGKKSATVLVKVYDTPGPCP------------------SVKVKEVSRDSVTITWE 23062
Query: 1746 APQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1805
P G +V + + + TV K + L+ ++ L EG Y FR+ +
Sbjct: 23063 IPTIDGGAPVNNYIVEKREA---AMRAFKTVTTKCSKTLY-RISGLVEGTMYYFRVLPEN 23118
Query: 1806 -FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARP 1863
+ G E + E P + ++ S + + W G +T YV+EA
Sbjct: 23119 IYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK 23178
Query: 1864 SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
+ W +K + + + ++ L G Y FR+ A N+ G P +V Q
Sbjct: 23179 AGTERW---MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 23233
Score = 201 bits (512), Expect = 5e-51
Identities = 369/1646 (22%), Positives = 603/1646 (36%), Gaps = 237/1646 (14%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVIDGMS----- 418
++ LV F+ A+N AG + + T I + P LD T+ DG++
Sbjct: 13838 VTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGD 13897
Query: 419 --VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ A G P P +W K + + + TP S L I DAG YT
Sbjct: 13898 TIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSS-MLTIKYATRKDAGEYTIT 13956
Query: 477 ATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVTHDPRV 525
ATN G + V I+ +++ + T S + + R
Sbjct: 13957 ATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRE 14016
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRS 581
T R +W + + H +L + Y RV + G +S
Sbjct: 14017 TSRLLWTVVSEDIQSCRHVATKLIQGNE-------------YIFRVSAVNHYGKGEPVQS 14063
Query: 582 AHLRVRQL---PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWT 637
+++ P PE P +S V + ++W +P D G S + Y +E E +
Sbjct: 14064 EPVKMVDRFGPPGPPEKP--EVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRW 14121
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP-PTAPPQN 696
V V GL +Y+FR+ A N G G S+ ++ V + + P PP N
Sbjct: 14122 VRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 14181
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILK--GYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
+ T +S + W P H +G L+ GY++ + G + T + ++
Sbjct: 14182 PHVTDTTKKSASLAWGKP---HYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVV 14238
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
DL Y ++A N AG+G + + + + P + AE + +R
Sbjct: 14239 PDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVEREMAPDFELDAELRRTLVVR----- 14292
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
G + + P + VT +D+I++ + ++ TE FT ++
Sbjct: 14293 ----------AGLSIRIFVPIKGRPAPEVTWT---KDNINLKNRANIEN-TESFTLLII- 14337
Query: 875 TTPGDGPRSTPQLVRTHE---------------DVPGPVGHLSFSEILDTSLKVSWQEPG 919
P T + V T E D PGPV +L ++I S+ + W P
Sbjct: 14338 --PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14395
Query: 920 EKNGI-LTGYRISWEEYNR----TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
G +T Y + E R T T H Y+VTGL+ Y V A
Sbjct: 14396 IDGGSRITNYIVEKREATRKSYSTATTKCH-----KCTYKVTGLSEGCEYFFRVMAENEY 14450
Query: 975 GQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVG 1033
G G+ + +T E P PP +L I +I +V+L + +P +DG + I+ +++EAQ
Sbjct: 14451 GIGEPTETT-EPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRK 14509
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
++W I + V +L Y+F++ VN G S
Sbjct: 14510 ---GSDQWTHITTVKG----LECVVRNLTEGEEYTFQVMAVNSAGRS------------- 14549
Query: 1094 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESV-------GYKIKYSRSDGHGK 1146
AP + P V +T LPE++ G + + K++
Sbjct: 14550 APRESRPVIVKEQTM-----------LPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKP 14598
Query: 1147 TLSHVVQDRVERDYTIEDLEEW-TEYRVQVQAFNAIGSGPWSQT---VVGRTRESV---- 1198
T++ D++ + + E T + + SGP+ T +VG + +
Sbjct: 14599 TVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQV 14658
Query: 1199 -----PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV 1253
P +GP ++ S + W + PE D + Y V ++ DS T
Sbjct: 14659 HDIPGPPTGPIKFDEVS--SDFVTFSW-DPPENDGGVPISNYVVEMRQTDSTTWVELATT 14715
Query: 1254 EGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEV 1312
++ A T L + Y+ +V A R G G + I+ VPGPP V
Sbjct: 14716 VIRTTYKA--TRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAV 14773
Query: 1313 RTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY 1371
S+ + W P + G IL Y + + + L P + ++GL Y
Sbjct: 14774 TKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPG-NIFKSSGLTDGIAY 14832
Query: 1372 LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE-----------DVRARSVLL 1420
FR+ A+ G + +P PS PM+ + ++ +V L
Sbjct: 14833 EFRVIAENMAG--------------KSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTL 14878
Query: 1421 SW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKAT 1479
W +P G + Y ++ R+LP+GRW + S + + F V L +Y+FRV A
Sbjct: 14879 KWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFS-NILENEFTVSGLTEDAAYEFRVIAK 14937
Query: 1480 NDIGD-SEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFR 1538
N G S SE S+++T EAP I T +L + FR
Sbjct: 14938 NAAGAISPPSEPSDAITCRDDV--EAPKIKVDVKFKDTVILKAGE------------AFR 14983
Query: 1539 IRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIR 1598
+ + G P W++ + + + +NK
Sbjct: 14984 LEA-----------DVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRR-D 15031
Query: 1599 MSVYNAVGEGPSSPPQEVFVGEAVPTAAPRN--VVVHGATATQLDVTWEPPPLDSQNGDI 1656
Y P + +F + + P + V T+ + ++W PP LD I
Sbjct: 15032 SGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPP-LDDGGAKI 15090
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
Y + E R T + + + +K+ L Y+ V A N G G S P
Sbjct: 15091 DHYIVQKRETSRLAWTNVASEVQVTK--LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 15148
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIV 1774
P P + + + +T S+ V W P G E + E + +
Sbjct: 15149 VLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS-EIINYIVERRDKAG--QRWI 15205
Query: 1775 TVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGA------PGPP 1828
+ K + L KV L EG Y FRI A+ I A T P A PGPP
Sbjct: 15206 KCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN---AAGISAPSPTSPFYKACDTVFKPGPP 15262
Query: 1829 GVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 1886
G P ++ S S+I+I W+ G IT Y++E +E W I+ + +SYT +
Sbjct: 15263 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 15322
Query: 1887 MDILKPGVSYDFRVIAVNDYGFGTPS 1912
L Y R+ A+N G G P+
Sbjct: 15323 G--LTENQEYKIRIYAMNSEGLGEPA 15346
Score = 201 bits (510), Expect = 8e-51
Identities = 370/1602 (23%), Positives = 611/1602 (38%), Gaps = 215/1602 (13%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G +V L G P P ++W+K +L + +L + + D+G
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLCTLELFSVNRKDSG 12867
Query: 472 TYTCLATNSRGVDEASADLVVW------ARTRITKPPQDQSVIKGTQ-----ASMVCGVT 520
YT A NS G A+ L V A +I K D++++ S +
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927
Query: 521 HDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
D R T R W + AT+ S +L C G D
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFR----------ICAENKYGVGDPV 12977
Query: 581 SAHLRVRQLPHAP----EHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP 635
+ + P+ P + PV +S + + + ++W P D G SP+ Y+LE E A
Sbjct: 12978 FTEPAIAKNPYDPPGRCDPPV--ISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAV 13035
Query: 636 -WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEP--PTA 692
WT + + T + GL Y+FR+ A+N G G+ S D + + +P P
Sbjct: 13036 NWTKVNRKPIIERT-LKATGLQEGTEYEFRVTAINKAGPGKPS-DASKAAYARDPQYPPG 13093
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIR--------YCLAGLPVGYQFKNI 744
PP T S+ + W P + I+ GY++ + LP Q
Sbjct: 13094 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPII-GYLVEVKRADSDNWVRCNLPQNLQK--- 13149
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
T +V L+ ED T Y+ V A N G S + + + P G + A+
Sbjct: 13150 TRFEVTGLM-ED----TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 13204
Query: 805 STTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT-ARPNFQDSIHVGFVSGLKK 863
+ +R G + + P + +T ++PN +G K
Sbjct: 13205 TLILR---------------AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDI---K 13246
Query: 864 FTEYFTSVLC------------FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
T++ T + C T + +V D PGP +++ EI S
Sbjct: 13247 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13306
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
V+W+ P G + Y + + R + + T +RV L +Y V A
Sbjct: 13307 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT-SFRVANLEEGKSYFFRVFA 13365
Query: 971 MTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVE 1029
G G T + + PGP +L + ++ S ++ ++ P DG + I ++V+
Sbjct: 13366 ENEYGIGD-PGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 13424
Query: 1030 AQVGVVGEGEEWL-LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
+ E +W ++ LS + A+ DL Y+FR+ N G PS+
Sbjct: 13425 ----FLTEENKWQRVMKSLSLQYSAK-----DLTEGKEYTFRVSAENENGEGTPSEI--- 13472
Query: 1089 IQTLQAPPDMAPANVSLR-------TASETSLW-----LRWMPLPEMEYNGNPESVGYKI 1136
T+ A D+ ++ L+ A E S + ++ P P + + + +
Sbjct: 13473 --TVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT 13530
Query: 1137 KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGS--GPWSQTVVGRT 1194
+ S V V + D ++ + + N G+ G S VVG+
Sbjct: 13531 RVS-----------VESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13579
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE 1254
+P+ GP + T+ +M ++W+ P+ D + Y + +++DS
Sbjct: 13580 --GIPT-GPIKFDEV--TAEAMTLKWAP-PKDDGGSEITNY--ILEKRDSVNNKWVTCAS 13631
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTR--IGDGSPSHPPILERTLD--DVPGPPMGILFP 1310
+ ++T L + + Y +V A + +G+G S P + D D P PP +
Sbjct: 13632 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV--- 13688
Query: 1311 EVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTT----ANTATVEVLAPSARQYTATGL 1365
+VR SV L W P G I Y + + + AN + + R + TGL
Sbjct: 13689 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM-----RDFKVTGL 13743
Query: 1366 KPESVYLFRITAQTRKGWGEAA---EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW 1422
Y FR+ A G G+ + E +V D PP +P V ++ SV L W
Sbjct: 13744 TEGLEYEFRVMAINLAGVGKPSLPSEPVVAL----DPIDPPGKPEVI--NITRNSVTLIW 13797
Query: 1423 -EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND 1481
EP DG + Y ++ R+LPS W + + V+ +F V L Y+FR++A N
Sbjct: 13798 TEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13856
Query: 1482 IGDSEFSEESESLTTLQAAPD-EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIR 1540
G S SES T+ + EAPTI+ P +D G I+
Sbjct: 13857 AG--AISAPSESTETIICKDEYEAPTIVL-------------DPTIKD-------GLTIK 13894
Query: 1541 YRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL----SRPSLTQYELDNLNKHRRYE 1596
+ + L ++ G P ++W++ ++ S P+ + + + E
Sbjct: 13895 AGDTIV--LNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 13952
Query: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
++ N G + + V V P V + +A + +TW PP L+ I
Sbjct: 13953 YTITATNPFG----TKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP-LEDGGSPI 14007
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTP 1714
+ Y + E R L V + V K + G Y+ V+A N G G +S P
Sbjct: 14008 KSYILEKRETSR-LLWTVVSEDIQSCRHVATKLIQG-NEYIFRVSAVNHYGKGEPVQSEP 14065
Query: 1715 TQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKI 1773
+ + P P + S +T + VSW+ P G + GY + + V I
Sbjct: 14066 VKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAI 14125
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGA--PGPPGV 1830
T S L KV L EG TY FR+ A+ GP EA+ + + A PGPP
Sbjct: 14126 KTPV----SDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSN 14181
Query: 1831 PIIVRYSSAIA-IHWSSGDPGKG-PITRYVIEARPSDEGLWDILIKDIPKEVSSYT-FSM 1887
P + + A + W G IT YV+E + + W IKD T F +
Sbjct: 14182 PHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVV 14238
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPS-SPSQSVPAQKANPFYE 1928
L+ Y+FR+ A+ND G G P+ P + ++ P +E
Sbjct: 14239 PDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFE 14280
Score = 200 bits (508), Expect = 1e-50
Identities = 369/1617 (22%), Positives = 631/1617 (39%), Gaps = 210/1617 (12%)
Query: 477 ATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
A N+ GV + SA + R PP + V +GT ++V + P T+ W
Sbjct: 9596 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLT--W 9653
Query: 532 EKDGATLGTESHP--------RIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
K P ++ +D +L I Q+ D G YT ++ G S+
Sbjct: 9654 FKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 9713
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
L V P P P+ +V + L+W P D G S + Y++E E N V ++S
Sbjct: 9714 LNVLGRPGPPVGPIK-FESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSS 9772
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--------PP 694
+PK + T+ L+ Y FR+ A N G G+ L EP TA P
Sbjct: 9773 -EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE--------PLDSEPETARNLFSVPGAP 9823
Query: 695 QNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL 754
S T S+ + W+ P E + GY + ++K + + + L
Sbjct: 9824 DKPTVSSVTRNSMTVNWEEP-EYDGGSPVTGYWLEMKDT---TSKRWKRVNRDPIKAMTL 9879
Query: 755 ------EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST-- 806
LI ++Y+ V A N+AG+G S T + P PPG + T+ T
Sbjct: 9880 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD-PIAPPGPPFPKVTDWTKS 9938
Query: 807 TIRFTWNAP---SPQFINGINQGYKLIA---WEPEQEEEVTMVTARPNFQDSIHVGFVSG 860
+ W+ P + G YK WE +++EV V+G
Sbjct: 9939 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL-----------VVTG 9987
Query: 861 LKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEP- 918
LK+ Y V G G P ++ + + P D L S ++
Sbjct: 9988 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP----------DLQLDASVRDRI 10037
Query: 919 -GEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVT-GLTALTTYTI---------E 967
G++ RI + VT + TL T TA+++ +
Sbjct: 10038 VVHAGGVI---RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQG 10094
Query: 968 VAAMTSKGQGQVSASTISSGVPPELPGPP-TNLGISNIGPRSVTLQ-FRPGYDGKTSISR 1025
V ++ +K + TI V ++PGP T N+ S L F P DG + I+
Sbjct: 10095 VYSLLAKNEAGERKKTIIVDVL-DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITN 10153
Query: 1026 WLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 1085
+++E + + W + +A V L Y FR+ N +G P +
Sbjct: 10154 YVIEKRES---DRRAWTPVTYTVTRQNAT---VQGLIQGKAYFFRIAAENSIGMGPFVET 10207
Query: 1086 SRKIQTLQAPPDMA--PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG 1143
S + ++ P + P ++ ++ ++ ++ L W P +Y+G E + Y ++ SR G
Sbjct: 10208 SEAL-VIREPITVPERPEDLEVKEVTKNTVTLTWNP---PKYDGGSEIINYVLE-SRLIG 10262
Query: 1144 HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWS---QTVVGRTRESVPS 1200
K + + R YT++ L+E Y +V A N +G G S + + + + P+
Sbjct: 10263 TEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPT 10322
Query: 1201 ---SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS-DTQPRFWLVEGN 1256
++ + ++ R+S P+ + V+ ++ T P +E
Sbjct: 10323 LHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALE-- 10380
Query: 1257 SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTT 1315
A+ + GKY + + + + S + + D PGPP+G + F EV
Sbjct: 10381 -KIKAKRSDSGKYCVV---------VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10430
Query: 1316 SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV-YLFR 1374
+ + W+PP G + I + + V + SA+ E Y+FR
Sbjct: 10431 YMVISWKPPLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKLLEGKDYIFR 10488
Query: 1375 ITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
I A+ G + + + + R R P P +P+V + V S L++W DG P+
Sbjct: 10489 IHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE--VTKDSALVTWNKPHDGGKPIT 10546
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESES 1493
Y ++ RE S RWA + H + F V L Y+FRV A N+IG + S S+
Sbjct: 10547 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10606
Query: 1494 LTTLQAAPDEAPTILSVTPHTT-TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGF 1552
+ +P + TT SV + WQPP D +LG+ + Y+++ E R
Sbjct: 10607 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG-GSKILGYIVEYQKVGDEEWR-- 10663
Query: 1553 TLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSS 1611
R + P S P T+Y++ L + Y+ R+ NA GE P+
Sbjct: 10664 --RANHTPE---------------SCPE-TKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 10705
Query: 1612 PPQEVFVGEAVPTAAPRNVVVHGATATQLDV-TWEPPPLDSQNGDIQGYKIYFWEAQRGN 1670
P+ V V + + P +++ A + + + L + + K+ + + R
Sbjct: 10706 VPEPVLVKDRL---EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA 10762
Query: 1671 LTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSV 1730
T+ + + ++++N + S+ N AG T + P P +
Sbjct: 10763 PTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGS---KTVSVKVLVLDKPGPPRDL 10819
Query: 1731 KFSELTTTSVNVSWEAP------QFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPL 1784
+ SE+ S ++W+ P N ++E + SP+ SK K +
Sbjct: 10820 EVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSK-----KKSHF-- 10872
Query: 1785 WLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAP--GPPGVPIIVRY----S 1837
K L EG Y FR+ A+ + GP +E T P + PPG P + +
Sbjct: 10873 ---AKHLNEGNQYLFRVAAENQYGRGPFVE---TPKPIKALDPLHPPGPPKDLHHVDVDK 10926
Query: 1838 SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSY 1896
+ +++ W+ D G PIT Y++E + +EG D + K V++ + L+ G +Y
Sbjct: 10927 TEVSLVWNKPDRDGGSPITGYLVEYQ--EEGTQDWIKF---KTVTNLECVVTGLQQGKTY 10981
Query: 1897 DFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEEWWFLVVIALVGLIFI--LLLVFVLIIR 1954
FRV A N G G P + ++P + L V + GL+ + F IIR
Sbjct: 10982 RFRVKAENIVGLGLPDT---TIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIR 11038
Query: 1955 GQSKKYAKKTDSGNSAKSGALGHSEMMSLDESSFPALELNNRRLSVKNSFCRKNGLY 2011
G AK T G+ K+ E +++ +F ++ L++KN R G Y
Sbjct: 11039 GVPVPTAKWTTDGSEIKT-----DEHYTVETDNFSSV------LTIKNCLRRDTGEY 11084
Score = 200 bits (508), Expect = 1e-50
Identities = 379/1720 (22%), Positives = 629/1720 (36%), Gaps = 216/1720 (12%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAIT-LENTLVILSTVAPDAGRYY 182
V H + ++ P P VTW + R +P + I T + +++VI + G Y
Sbjct: 10038 VVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYS 10097
Query: 183 VQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANAR 242
+ A N+ KT I + V +V GP T + T+ + + E +
Sbjct: 10098 LLAKNEAGERKKT---IIVDVLDVPGPVG----TPFLAHNLTNESCKLTWFSPE--DDGG 10148
Query: 243 PLIKLHIIWKKDG---VLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG 299
I ++I K++ + + T+ A ++ A P V
Sbjct: 10149 SPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETS 10208
Query: 300 AYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPP------PSITWYKDAAVVEVEK 353
L + EP + PER E+++V PP I + ++ ++ EK
Sbjct: 10209 EALVIREP---ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10265
Query: 354 LTRFRQRN--DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL-- 409
+ N + GL DT ++ A N G+ + S + + L
Sbjct: 10266 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10325
Query: 410 ----DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
T+ G + L SG P+P ++W K E + + TP I
Sbjct: 10326 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 10385
Query: 466 HISDAGTYTCLATNSRG----------------------VDEASADLVVWARTRITKPPQ 503
SD+G Y + NS G DE + D +V + KPP
Sbjct: 10386 R-SDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVIS----WKPPL 10440
Query: 504 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
D S + + + + +W + ++ ++ G +I + + +
Sbjct: 10441 DDG------GSKITNYIIEKKEVGKDVW-MPVTSASAKTTCKVSKLLEGKDYIFRIHAEN 10493
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLI 623
+ + ++S DS A R R +P AP+ P+ T V + + +TW KP DG P+
Sbjct: 10494 LYGISDPLVS----DSMKAKDRFR-VPDAPDQPIVT--EVTKDSALVTWNKPHDGGKPIT 10546
Query: 624 RYILEMSEN-NAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER 682
YILE E + W + T V L+ Y+FR+ A N++G G S ++
Sbjct: 10547 NYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10606
Query: 683 VSLPEE-PPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQF 741
V + +PP N A T S+ + WQPP + IL GYI+ Y G +
Sbjct: 10607 VFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKIL-GYIVEYQKVGDEEWRRA 10665
Query: 742 KNITDA-DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV-H 799
+ ++ + L Y+ V A N+AG + V E L PP +
Sbjct: 10666 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES-DPAHVPEPVLVKDRLEPPELILD 10724
Query: 800 AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS 859
A I+ I G+ + + W+ E + T D VG
Sbjct: 10725 ANMAREQHIKVGDTLRLSAIIKGV--PFPKVTWKKEDRDAPTKARI-----DVTPVGSKL 10777
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
++ + T T + D PGP L SEI S ++W+EP
Sbjct: 10778 EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL 10837
Query: 920 EKNG-ILTGYRI--------SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA 970
+ G ++T Y + W + T+ + +H+ + L Y VAA
Sbjct: 10838 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH---------LNEGNQYLFRVAA 10888
Query: 971 MTSKGQGQV--SASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWL 1027
G+G + I + P PGPP +L ++ V+L + +P DG + I+ +L
Sbjct: 10889 ENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYL 10948
Query: 1028 VEAQVGVVGEG-EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS-PPSQP 1085
VE Q EG ++W+ ++N V L Y FR++ NIVG P +
Sbjct: 10949 VEYQ----EEGTQDWIKFKTVTN----LECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI 11000
Query: 1086 SRKIQTLQAPPD-------MAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY 1138
+ Q PP + V T +R +P+P ++ + +
Sbjct: 11001 PIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI------ 11054
Query: 1139 SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESV 1198
++D H V D TI++ Q+ NA GS V T V
Sbjct: 11055 -KTDEH----YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGS---KTVAVHLTVLDV 11106
Query: 1199 PS--SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLV--E 1254
P +GP N+ L T M + W + P+ D V+ Y V + DT+ W V
Sbjct: 11107 PGPPTGPINI--LDVTPEHMTISW-QPPKDDGGSPVINYIV----EKQDTRKDTWGVVSS 11159
Query: 1255 GNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVR 1313
G+S ++ L K Y +V A +IG G P P + + P PP + ++
Sbjct: 11160 GSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDIT 11219
Query: 1314 TTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+ + W P + G I Y + R T V + ++ TGL + Y
Sbjct: 11220 ENAATVSWTLPKSDGGSPITGYYMERR--EVTGKWVRVNKTPIADLKFRVTGLYEGNTYE 11277
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLS 1430
FR+ A+ G + + + + P PP P ++ + R + L+ +P SDG S
Sbjct: 11278 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS-RETADLVWTKPLSDGGS 11336
Query: 1431 PVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
P+ Y ++ ++ + +W + +F V L Y+FR+KA N +G+ E E
Sbjct: 11337 PILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11396
Query: 1491 SESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLR 1550
+ES+ A IL P V R + + +G IR
Sbjct: 11397 AESVI--------AKDILH-PPEVELDVTCR-------DVITVRVGQTIRILA------- 11433
Query: 1551 GFTLRGINNPGATWAELTSMY-------SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
++G P TW + + +++L R L E + H +Y I S N
Sbjct: 11434 --RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRAD-HGKYII--SAKN 11488
Query: 1604 AVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF 1663
+ G S V +N+ V T ++WE PLD+ +I + + +
Sbjct: 11489 SSGHAQGS----AIVNVLDRPGPCQNLKVTNVTKENCTISWE-NPLDNGGSEITNFIVEY 11543
Query: 1664 -------WEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP---RS 1712
W ++T+R +K LA N Y V A N G GP
Sbjct: 11544 RKPNQKGWSIVASDVTKRLIKANLLANNE-----------YYFRVCAENKVGVGPTIETK 11592
Query: 1713 TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
TP P P ++ ++ T V + W P + G
Sbjct: 11593 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGG 11632
Score = 198 bits (503), Expect = 5e-50
Identities = 328/1450 (22%), Positives = 557/1450 (38%), Gaps = 178/1450 (12%)
Query: 523 PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSA 582
P+VT W K G +D L I + D G Y+ +++ G +
Sbjct: 12139 PKVT----WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12194
Query: 583 HLRVRQLPHAPEHPVATL--STVERRAINLTWTKPF-DGNSPLIRYILEMSE-NNAPWTV 638
++RV P PV+ L S V + + +++W P DG S + YI+E E + W+
Sbjct: 12195 NVRVLDTPG----PVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWST 12250
Query: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA--PPQN 696
+ V K TS V LVP Y FR+ AVN+ G G D + L +P + PP+
Sbjct: 12251 VTPEV--KKTSFHVTNLVPGNEYYFRVTAVNEYGPG-VPTDVPKPVLASDPLSEPDPPRK 12307
Query: 697 VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED 756
+ + T S + W PP + GYI Y P + D+ +L++
Sbjct: 12308 LEVTEMTKNSATLAWLPPLRD-GGAKIDGYITSYREEEQPADRWTEYSVVKDL-SLVVTG 12365
Query: 757 LIIWTNYEIEVAAYNSAGL-------GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIR 809
L Y+ VAA N+ G+ GVY +K L + P + +A I
Sbjct: 12366 LKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE---QLLPPKILMPEQITIKAGKKLRIE 12422
Query: 810 -FTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYF 868
+ P P W+ ++E VT + DS + + + + +
Sbjct: 12423 AHVYGKPHP-----------TCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 12471
Query: 869 TSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
S+ + G + +V D PG P S+I + +SW P E G +T
Sbjct: 12472 YSLTAENSSGTDTQKIKVVVM---DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 12528
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTIS 985
Y + + +R + VT RV L Y V A G + +++ +
Sbjct: 12529 NYIVEKCDVSRGDW-VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 12587
Query: 986 SGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLI 1044
+ P +P P N ++ + + + + RP DG + I +L+E + E L+
Sbjct: 12588 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK-------ERNSLL 12640
Query: 1045 HQLSNEPDARSMEVP--DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQT-LQAPPDMAPA 1101
+N+ RS E P L YSFR+ +N G+SPPS+P+ + + P P
Sbjct: 12641 WVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE 12700
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
+ + ++ + +W R +++G + +GY ++ + G + ++ + +Y
Sbjct: 12701 VIDVTKSTVSLIWAR------PKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 12754
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRW 1220
T LEE +Y+ + A A+ P S+ T + + P + S + V+
Sbjct: 12755 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPVT--ILAENVPPRIDLSVAMKSLLTVKA 12812
Query: 1221 SEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLG-KYVLYEVQVLAF 1279
+ L V K + + W +G + A+ + + L +++ +
Sbjct: 12813 G-------TNVCLDATVFGKPMPTVS----WKKDGTLLKPAEGIKMAMQRNLCTLELFSV 12861
Query: 1280 TRIGDG---------SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
R G S S ++ + D PGPP + ++ + L W+PP G
Sbjct: 12862 NRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS 12921
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA-EA 1389
+ I + T+ N A V P + L Y FRI A+ + G G+
Sbjct: 12922 EITNYIVDKRETSRPNWAQVSATVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTE 12980
Query: 1390 LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWA 1448
+ D P P++ ++ + +SW+ P DG SP+ Y ++ RE + W
Sbjct: 12981 PAIAKNPYDPPGRCDPPVI--SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWT 13038
Query: 1449 LHSASVSHNASSFIVDR------LKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA-P 1501
+ I++R L+ T Y+FRV A N G + S+ S++ P
Sbjct: 13039 KVNRKP-------IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYP 13091
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
P V T +SV + W PA D + I+ G+ +
Sbjct: 13092 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPII----------------GYLVEVKRADS 13135
Query: 1562 ATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG-EGPSSPPQE----- 1615
W +++ T++E+ L + +Y+ R+ N +G PS P +
Sbjct: 13136 DNWVRCNLPQNLQK------TRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 13189
Query: 1616 -VFVGEAVPTAAPRNVVVHGATATQ---LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL 1671
+ E A R ++ A T + V PPP KI W NL
Sbjct: 13190 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPP-----------KI-TWSKPNVNL 13237
Query: 1672 TERV-----KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSA 1726
+R+ T F + ++ +N+ Y A + N+ G + T P
Sbjct: 13238 RDRIGLDIKSTDF--DTFLRCENVNKYDAGKYILTLENSCG---KKEYTIVVKVLDTPGP 13292
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P +V E++ S V+WE P G +V + + S + T K +
Sbjct: 13293 PVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTS----F 13348
Query: 1787 KVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAPGPPGVPIIVR--YSSAIAIH 1843
+V +L EG +Y FR+ A+ + G E + PGP V + VR S+ +I
Sbjct: 13349 RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQ-TPGPV-VDLKVRSVSKSSCSIG 13406
Query: 1844 WSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
W G I YV++ ++E W ++K + S +S L G Y FRV A
Sbjct: 13407 WKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-----SLQYSAKDLTEGKEYTFRVSA 13460
Query: 1903 VNDYGFGTPS 1912
N+ G GTPS
Sbjct: 13461 ENENGEGTPS 13470
Score = 195 bits (495), Expect = 5e-49
Identities = 428/1972 (21%), Positives = 746/1972 (37%), Gaps = 272/1972 (13%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP 135
++++ L F+R N+ G R+ + V E E +RA
Sbjct: 19935 HVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAG 19994
Query: 136 R-------IASFPQPQVTWFRDGRKIPPSSRI--AITLEN-TLVILSTVAPDAGRYYVQA 185
I+ P P+VT RDG + + R IT EN T+ + +V DAGRY + A
Sbjct: 19995 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 20054
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVA--------GTSEVTLEC 237
N T I + V + GP P P +I SV G S+VT
Sbjct: 20055 ANSSG---TTKAFINIVVLDRPGP--PTGPVVISDITEESVTLKWEPPKYDGGSQVTNYI 20109
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI---------SDHNRRLTIPNPTG-SDAGYYECEAV 287
+ +W + ++ + ++ R+ N G SD C V
Sbjct: 20110 LLKRETSTA---VWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTV 20166
Query: 288 LRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAA 347
+ P +++ + ++ VV + K SI W K
Sbjct: 20167 KLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD--RNSILWQKANK 20224
Query: 348 VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS--------------- 392
+V + T F+ +GL+ + F+ +A NAAG + S
Sbjct: 20225 LVI--RTTHFKVTTIS----AGLIYE----FRVYAENAAGVGKPSHPSEPVLAIDACEPP 20274
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRF 452
+ +T I+ N DG S + P W K F
Sbjct: 20275 RNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS------------F 20322
Query: 453 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV-------VWARTRITKPPQDQ 505
T + +IS + + A N+ G +++V + I P +
Sbjct: 20323 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYT 20382
Query: 506 SVIK---GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWS 561
V+K GT + G++ P TI W KD L T + + + S+ I
Sbjct: 20383 EVVKYRAGTSVKLRAGISGKPAPTIE--WYKDDKELQTNALVCVENTTDLASILIKDADR 20440
Query: 562 GDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNS 620
+ G Y ++ +A G+ S + +++ P P P+ TV I L W P D G +
Sbjct: 20441 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIE-FKTVTAEKITLLWRPPADDGGA 20499
Query: 621 PLIRYILEMSENN-APWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKD 679
+ YI+E E + W+++ ++ +T ++ Y FR+ AVN G G+ +
Sbjct: 20500 KITHYIVEKRETSRVVWSMVSEHLEE--CIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20557
Query: 680 TERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII----RYCLAGL 735
V+ PP + T S+ + W P + I GY + + L
Sbjct: 20558 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI-SGYFLEKRDKKSLGWF 20616
Query: 736 PVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPP 795
V + T V L ++Y+ V A N+AG G +S +E+ P PP
Sbjct: 20617 KVLKETIRDTRQKVTGLTEN-----SDYQYRVCAVNAAGQGPFSEP-SEFYKAADPIDPP 20670
Query: 796 G---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDS 852
G + + ++I W+ P + + GY ++ +EEE T V+ + + +
Sbjct: 20671 GPPAKIRIADSTKSSITLGWSKPVYDGGSAVT-GY-VVEIRQGEEEEWTTVSTKGEVRTT 20728
Query: 853 IHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEI-LDTS 910
+V VS LK Y+ V G G P + V+ + + P EI LD +
Sbjct: 20729 EYV--VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP-------EIDLDVA 20779
Query: 911 LKVSW-QEPGEKNGILTGYR------ISWEEYNRTNTRVTHY-LPNVTLEYRVTGLTALT 962
L+ S + GE +L ++ ++W + + Y + N +T
Sbjct: 20780 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 20839
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKT 1021
T + G G+ +ST+S V + P L + ++ +VTL + P DG +
Sbjct: 20840 NDTGKYILTIENGVGEPKSSTVSVKVL-DTPAACQKLQVKHVSRGTVTLLWDPPLIDGGS 20898
Query: 1022 SISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +++E + W ++ S++ + S ++ DL+ T + FR+ N +G
Sbjct: 20899 PIINYVIEKRDATK---RTWSVV---SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 20952
Query: 1082 PSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS 1141
P + + ++ + P + ++S++ +++TS+ L W + +++G Y ++ R
Sbjct: 20953 PCETTEPVKAAEVPAPIR--DLSMKDSTKTSVILSWT---KPDFDGGSVITEYVVE--RK 21005
Query: 1142 DGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPS 1200
+T SH + + + L+E + +V A N G S P +
Sbjct: 21006 GKGEQTWSHAGISKT-CEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------VT 21051
Query: 1201 SGPTNVSALATTSSSMLVRWSEVPEAD---RNGLVLGYKVMYKEKDSDTQPRFWLVEGNS 1257
GP V L T V S++P A R G + ++ YK K + WL +G
Sbjct: 21052 IGPITVKELIITPE---VDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSIS--WLKDGLP 21106
Query: 1258 SRSAQLTGLGKY---VLYEVQVLA------FTRIGDGSPSH--PPILERTLDDVPGPPMG 1306
+ ++ K + ++ +T I D + PI TL P
Sbjct: 21107 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 21166
Query: 1307 ILFPEVRTTSVRLIWQPPAAPNG-IILAYQITHRLNTTTANTATVEVLAPSARQ-YTATG 1364
I F E++ SV L W P G I Y I R T+ T V + AR +
Sbjct: 21167 IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR---ETSQTNWKMVCSSVARTTFKVPN 21223
Query: 1365 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRARSVLLSWE 1423
L ++ Y FR+ A+ R G + + ++ + + R P PP +P++ +V + + L+W+
Sbjct: 21224 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY--NVTSDGMSLTWD 21281
Query: 1424 -PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
P DG S V + ++ +E S W + S + + L Y+FRV A N
Sbjct: 21282 APVYDGGSEVTGFHVEKKERNSILWQKVNTSPI-SGREYRATGLVEGLDYQFRVYAENSA 21340
Query: 1483 GDSEFSEESE-SLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRY 1541
G S S+ S+ +L P P + VT T T ++W PP D + I+ G+ I
Sbjct: 21341 GLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETIT---LKWNPPLRDGGSKIV-GYSIEK 21396
Query: 1542 RELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSV 1601
R+ W N + S QY + L+ RYE R+
Sbjct: 21397 RQ----------------GNERWVRC-------NFTDVSECQYTVTGLSPGDRYEFRIIA 21433
Query: 1602 YNAVGEGPSSPPQE-----VFVGEAVPTAAP------RNVVVHGATATQLDVTWEPPPLD 1650
NAVG SPP + + E VP +++ + ++ + P+
Sbjct: 21434 RNAVGT--ISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVP 21491
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
G +I +R N+ T L S+ +++ T + +V A NA+G
Sbjct: 21492 RVTWFKDGVEI----EKRMNMEI---TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21544
Query: 1711 RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV 1770
+ Q P ++F+ +T + + W+AP + + C+P+
Sbjct: 21545 AEIKVKVQDTPGKVVGP--IRFTNITGEKMTLWWDAP------------LNDGCAPITHY 21590
Query: 1771 SKIVTVDVKGNSPL-WLKVKDLAE-----------GVTYRFRIRA-KTFTYGPEIEANVT 1817
++ + S L W ++D E G Y+FR+ A F G ++++
Sbjct: 21591 ----IIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPV 21646
Query: 1818 TGPGE-GAPGPPGVPIIVRYS-SAIAIHWSSGDP-GKGPITRYVIEARPSDEGLWDILIK 1874
+ P PG+P + ++I + W+ + G I +Y++E R W +I
Sbjct: 21647 VAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVIS 21706
Query: 1875 DIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQK-ANP 1925
P +S F + L G Y+F V+A N G G S S+ + ++ NP
Sbjct: 21707 KRP--ISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNP 21756
Score = 193 bits (490), Expect = 2e-48
Identities = 350/1604 (21%), Positives = 572/1604 (35%), Gaps = 169/1604 (10%)
Query: 378 FQCFARNAAGEVQTSTYLAVTS---IAPNIT-RGPLDSTVI--DGMSVVLACETSGAPRP 431
F+ A N GE S V +AP++ +G D + + + L G P P
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13515
Query: 432 AITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV 491
+++W+KGE LA+ ++ + + +L++ SDAG YT N G E + +
Sbjct: 13516 SVSWKKGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 13574
Query: 492 VWARTRITKPPQDQSVIKGTQASMVCGVTHDP--RVTIRYIWEK----DGATLGTESHPR 545
V + I P + ++ D YI EK + + S +
Sbjct: 13575 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 13634
Query: 546 IRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
R LH ++ + + G +P AP P + V
Sbjct: 13635 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP--PPPNIVDVRH 13692
Query: 606 RAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFR 664
+++LTWT P G SP+ Y LE E N+ + V GL Y+FR
Sbjct: 13693 DSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFR 13752
Query: 665 LCAVNDVGKGQFSKDTERVSLPEEP-----PTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
+ A+N G G + SLP EP P PP T S+ + W P +
Sbjct: 13753 VMAINLAGVG-------KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP--KYD 13803
Query: 720 NG-ILKGYIIRYCLAGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
G L GYI+ LP K N + + DL+ YE + A N+AG
Sbjct: 13804 GGHKLTGYIVE--KRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13861
Query: 778 YSSKVTEW----------TLQGVPTVPPG-NVHAEATNSTTIRFTWNAPSPQFINGINQG 826
S+ TE T+ PT+ G + A T P P+ + ++
Sbjct: 13862 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPK--SSWSKA 13919
Query: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQ 886
K I + ++T +T+ P + +K T T
Sbjct: 13920 GKDI-----RPSDITQITSTP-------TSSMLTIKYATRKDAGEYTITATNPFGTKVEH 13967
Query: 887 LVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
+ T DVPGP G + S + ++W P E G + Y + E +R V
Sbjct: 13968 VKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE 14027
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPTNLGISNI 1004
+ + T L Y V+A+ G+G+ V + + PGPP +SN+
Sbjct: 14028 -DIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNV 14086
Query: 1005 GPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNP 1063
+ T+ + RP DG + I+ + VE + E + + + +V L
Sbjct: 14087 TKNTATVSWKRPVDDGGSEITGYHVERR-----EKKSLRWVRAIKTPVSDLRCKVTGLQE 14141
Query: 1064 FTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPE 1122
+ Y FR+ N G PPS+ S + A P P+N + ++ S L W +
Sbjct: 14142 GSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAW---GK 14198
Query: 1123 MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG 1182
Y+G E GY +++ + + + DL+ +Y ++ A N G
Sbjct: 14199 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14258
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
G + V E V + A +++VR L ++ K
Sbjct: 14259 VG---EPAVIPDVEIVEREMAPDFELDAELRRTLVVRAG-----------LSIRIFVPIK 14304
Query: 1243 DSDTQPRFWLVEG-NSSRSAQLTGLGKYVL--------YEVQVLAFTRIGDGSPSHPPIL 1293
W + N A + + L Y+ T +
Sbjct: 14305 GRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14364
Query: 1294 ERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVL 1353
R L D PGP + + ++ SV L W P G + I + T + +T
Sbjct: 14365 VRVL-DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTK 14423
Query: 1354 APSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRP-MVQQED 1412
Y TGL Y FR+ A+ G GE E TTE + PS P + D
Sbjct: 14424 CHKC-TYKVTGLSEGCEYFFRVMAENEYGIGEPTE----TTEPVKASEAPSPPDSLNIMD 14478
Query: 1413 VRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTS 1471
+ +V L+W +P DG S + Y I+ + S +W H +V +V L
Sbjct: 14479 ITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWT-HITTV--KGLECVVRNLTEGEE 14535
Query: 1472 YKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKIN 1531
Y F+V A N G S P + V+++ Q +
Sbjct: 14536 YTFQVMAVNSAGRS-------------------------APRESRPVIVKEQTMLPE--- 14567
Query: 1532 GILLGFRIRYRELLY----EGLR-GFTLRGINNPGATWAELTSMYSM-RNLSRPSLTQYE 1585
L R Y++L+ + ++ + G P TW + + + ++ +
Sbjct: 14568 ---LDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 14624
Query: 1586 LDNLNKHRRYE---IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDV 1642
+ N+N+ R + ++ N VGE +V PT + ++ +
Sbjct: 14625 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGP---IKFDEVSSDFVTF 14681
Query: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
+W+PP D I Y + + E T+ + K LT Y V A
Sbjct: 14682 SWDPPENDG-GVPISNYVVEMRQTDSTTWVELATTVI--RTTYKATRLTTGLEYQFRVKA 14738
Query: 1703 FNAAGDGPRSTPT--QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRL 1759
N G GP T P P + + + +T S+ +SW P G + GY +
Sbjct: 14739 QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHV 14798
Query: 1760 VYEPCSPV--DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVT 1817
+ + + VSK + V GN K L +G+ Y FR+ A+ +
Sbjct: 14799 ERKERNGILWQTVSKAL---VPGNI---FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSE 14852
Query: 1818 TGPGEGAPGPPGVPIIVRYS-SAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKD 1875
PPG P+ + + + + W+ + G IT Y++E R G W +K
Sbjct: 14853 PMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW---LKA 14909
Query: 1876 IPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG-FGTPSSPSQSV 1918
+ F++ L +Y+FRVIA N G PS PS ++
Sbjct: 14910 NFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAI 14953
Score = 193 bits (490), Expect = 2e-48
Identities = 343/1510 (22%), Positives = 596/1510 (39%), Gaps = 171/1510 (11%)
Query: 473 YTCLATNSRG-VDEASADLVVWARTRITKPP-----QDQSVIKGTQASMVCGVTHDPRVT 526
+ +A N +G D S + + A+ + +P SV G + ++ P+ T
Sbjct: 16704 FRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT 16763
Query: 527 IRYIWEKDGATLGTESHPRIR--LDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
I W KDG L + + LD +L I +T D G Y V + G + S +
Sbjct: 16764 IT--WTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQYGITVANVVGQKTASIEI 16820
Query: 585 RVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLLAS 642
P P+ PV V +I L+W P + G + YI++ + W V+ A+
Sbjct: 16821 VTLDKPDPPKGPVK-FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 16879
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERV--SLPEEPPTAPPQNVIAS 700
V T++ V L YQFR+ A N G+ F+ +++ + P + P PP A+
Sbjct: 16880 V--ARTTLKVTKLKTGTEYQFRIFAENRYGQS-FALESDPIVAQYPYKEP-GPPGTPFAT 16935
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED---- 756
+ S++IQW P + + ++ ++ R + +I VN ++ D
Sbjct: 16936 AISKDSMVIQWHEPVNNGGSPVIGYHLERK---------ERNSILWTKVNKTIIHDTQFK 16986
Query: 757 ---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWN 813
L YE V A N G+G +SK +E + P PPG I W
Sbjct: 16987 AQNLEEGIEYEFRVYAENIVGVGK-ASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 17045
Query: 814 APSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVL 872
P + G + + E+ + + +F + I F VSGL + Y V+
Sbjct: 17046 KPV------YDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVI 17099
Query: 873 CFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRI 930
G P + + ++V P +S ++ V+ E + G +
Sbjct: 17100 AKNAAGAISKPSDSTGPITAKDEVELP--RISMDPKFRDTIVVNAGETFRLEADVHGKPL 17157
Query: 931 SWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI--SSGV 988
E+ R + + + E + T AL ++ A GQ + AS + S
Sbjct: 17158 PTIEWLRGDKEIEE---SARCEIKNTDFKALLI--VKDAIRIDGGQYILRASNVAGSKSF 17212
Query: 989 PPEL-----PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEW 1041
P + PGPP + ++ + +L + P DG + IS ++VE + W
Sbjct: 17213 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRET---SRLAW 17269
Query: 1042 LLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPA 1101
++ ++E S++V L Y FR+ VN G P + + + P
Sbjct: 17270 TVV---ASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPK 17326
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ERDY 1160
++ + ++ S+ + W + +G E +GY ++ + D G + R+ +
Sbjct: 17327 SLEVTNIAKDSMTVCWN---RPDSDGGSEIIGYIVE--KRDRSGIRWIKCNKRRITDLRL 17381
Query: 1161 TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLV 1218
+ L E EY +V A NA G G P TV + + V GP TN + TT +S+ +
Sbjct: 17382 RVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITL 17441
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
W + P D +LGY V + D + G +++ L ++ Y+++V A
Sbjct: 17442 AWGK-PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17500
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH 1338
++G G + P + D + P + L E+R GI++ +
Sbjct: 17501 LNKVGLGEATSVPGTVKPEDKLEAPELD-LDSELR--------------KGIVVRAGGSA 17545
Query: 1339 RLNTTTANTATVEVL-APSARQYTATGLKPESVYLFRITAQT--RKGWGE---------A 1386
R++ T E+ + ++T + V +++ R G+
Sbjct: 17546 RIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG 17605
Query: 1387 AEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSG 1445
+++ VT + D P PP V++ VR S L WEP DG + V+ Y I RE S
Sbjct: 17606 SKSAFVTVKVLDTPGPPQNLAVKE--VRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--ST 17661
Query: 1446 RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAP 1505
R A + S + +SF V+ L Y FRV A N+ G E +++ A P P
Sbjct: 17662 RKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKA--AEPPSPP 17719
Query: 1506 TILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWA 1565
+++T + TS + W+ P D + +L G+ + E+ +G +++
Sbjct: 17720 GKVTLTDVSQTSASLMWEKPEHDGGSRVL-GYVV---EMQPKGTEKWSI----------- 17764
Query: 1566 ELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVP-- 1623
++ + + L+ + Y+ R+ YN G+ S P+ + V
Sbjct: 17765 ----------VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK---SDPRVLGVPVIAKDL 17811
Query: 1624 TAAPRNVVVHGATATQL--DVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA 1681
T P + + Q D+ E P + +I K + + T RV A
Sbjct: 17812 TIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVK----DGEPLKQTTRVNVEETA 17867
Query: 1682 ENSV---KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
++V K N + Y +V A N+AG + + P P V+F E++
Sbjct: 17868 TSTVLHIKEGNKDDFGKY--TVTATNSAGTATENLSVIVLEKPGPPVGP--VRFDEVSAD 17923
Query: 1739 SVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTY 1797
V +SWE P + G + Y + E +V+ V + +K+ L G Y
Sbjct: 17924 FVVISWEPPAYTGGCQISNY--IVEKRDTTTTTWHMVSATVARTT---IKITKLKTGTEY 17978
Query: 1798 RFRIRAKTFTYGP----EIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGK 1851
+FRI A+ YG + +A + P + PGPPG P + S + + W + G
Sbjct: 17979 QFRIFAEN-RYGKSAPLDSKAVIVQYPFK-EPGPPGTPFVTSISKDQMLVQWHEPVNDGG 18036
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
I Y +E + + LW L K ++ T +D G+ Y+F+V A N G G P
Sbjct: 18037 TKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD---EGLEYEFKVSAENIVGIGKP 18093
Query: 1912 SSPSQSVPAQ 1921
S S+ A+
Sbjct: 18094 SKVSECFVAR 18103
Score = 192 bits (489), Expect = 2e-48
Identities = 323/1397 (23%), Positives = 511/1397 (36%), Gaps = 198/1397 (14%)
Query: 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERR 606
R + L I + D GTYT + G+ R+ H+ V P P + T ++
Sbjct: 8958 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVT--DIKAE 9015
Query: 607 AINLTWTKPFD-GNSPLIRYILEM---SENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662
+ LTW P D G S + Y+++ S A W + + K + L+P Y+
Sbjct: 9016 SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK--LIPNGQYE 9073
Query: 663 FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722
FR+ AVN G K + V PP RT S+++ W PP ++ + I
Sbjct: 9074 FRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPI 9133
Query: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLED-------LIIWTNYEIEVAAYNSAGL 775
GY + G P + ++ A + + L+ L+ Y+ A N+AG+
Sbjct: 9134 -TGYWLEKREEGSP---YWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGI 9189
Query: 776 GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT---IRFTWNAPSPQFINGINQGYKLIAW 832
G S+ ++ + G P PPG T I W P+ + G + +
Sbjct: 9190 GP-PSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAK------DGGSPIKGY 9242
Query: 833 EPEQEEEVTMVTARPNFQDSIHVG---FVSGLKKFTEYFTSVLCFTTPGDGPRS--TPQL 887
E +EE T R N D + V LK+ +Y V G+ S T ++
Sbjct: 9243 IVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI 9302
Query: 888 VRTH-EDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYL 946
T ++ P + + L + P G T + SWE + + +
Sbjct: 9303 PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTP-KSSWEFDGKAKKAMKDGV 9361
Query: 947 PNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA------STISSGVP-PELPGPPTNL 999
++ + ++ + I + G+ ++A T + V ++PGPP +L
Sbjct: 9362 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9421
Query: 1000 GISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARS--M 1056
+S+I S L ++ P DG I +++E + +G+ W ++ PD S
Sbjct: 9422 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVN-----PDCGSTTF 9473
Query: 1057 EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQA--PPDMAPANVSLRTASETSLW 1114
VPDL Y FR+R N G PP + ++ PPD P + + ++ ++
Sbjct: 9474 VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPD-PPIKLKIGLITKNTVH 9532
Query: 1115 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ----DRVERDYTIEDLEEWTE 1170
L W P + +G Y ++ D G Q D E +T+EDL E E
Sbjct: 9533 LSWKP---PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGE 9589
Query: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
Y +V+A NA G S TV GP + S L + EV E
Sbjct: 9590 YEFRVKAVNAAGVSKPSATV-----------GPCDCQRPDMPPSIDLKEFMEVEEGTNVN 9638
Query: 1231 LV-----------LGYKVMYKEKDS------DTQPRFWLVEGNSSRSAQLTGLGKYVLYE 1273
+V +K K+ D+ DT +V+ + + LY
Sbjct: 9639 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLY- 9697
Query: 1274 VQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIIL 1332
+ A +G S + + PGPP+G I F V + L W PP G +
Sbjct: 9698 -TITAVNNLGTASKE----MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKI 9752
Query: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
+ + V P YT L Y+FRI AQ + G GE ++
Sbjct: 9753 TNYVIEKREANRKTWVHVS-SEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPE 9811
Query: 1393 TTEKR-DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALH 1450
T P P +P V V S+ ++W EP DG SPV Y ++ ++ S RW
Sbjct: 9812 TARNLFSVPGAPDKPTV--SSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRV 9869
Query: 1451 SASVSHNAS---SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
+ + S+ V L + Y+FRV A N G S S+ T P
Sbjct: 9870 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPF 9929
Query: 1508 LSVTPHTTTSVLIRWQPPAED---KINGILLGFR--------------IRYRELLYEGL- 1549
VT T +S + W PP +D K+ G ++ ++ +R +L+ GL
Sbjct: 9930 PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLK 9989
Query: 1550 ---------RGFTLRGINNPGATWAELTSMYSMRN-LSRP--SLTQYELDNLNKHRRYEI 1597
R + GI PG E+T + M++ L P L D + H I
Sbjct: 9990 EGAFYKFRVRAVNIAGIGEPG----EVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVI 10045
Query: 1598 RMSVYNAVGEGPS--------SPPQEVFV------------------------------G 1619
R+ Y + P+ + PQE + G
Sbjct: 10046 RIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10105
Query: 1620 EA----------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG 1669
E VP + H T +TW P D I Y I E+ R
Sbjct: 10106 ERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPE-DDGGSPITNYVIEKRESDRR 10164
Query: 1670 NLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQG---QTQQAAPSA 1726
T T + + ++ L AY +AA N+ G GP ++ + P
Sbjct: 10165 AWTP--VTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 10222
Query: 1727 PSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWL 1786
P ++ E+T +V ++W P++ G E V E S + G K V
Sbjct: 10223 PEDLEVKEVTKNTVTLTWNPPKYDGG-SEIINYVLE--SRLIGTEKFHKVTNDNLLSRKY 10279
Query: 1787 KVKDLAEGVTYRFRIRA 1803
VK L EG TY +R+ A
Sbjct: 10280 TVKGLKEGDTYEYRVSA 10296
Score = 190 bits (483), Expect = 1e-47
Identities = 365/1536 (23%), Positives = 598/1536 (38%), Gaps = 180/1536 (11%)
Query: 448 QLPRFTPLESGSLLISPTHISDAGT-------YTCLATNSRGV--DEASADLVVWARTRI 498
+LP +++ I TH G + +A N+ GV + + + + AR +
Sbjct: 15982 ELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEV 16041
Query: 499 TKPP-------QDQSVIKGTQASMV-CGVTHDPRVTIRYIWEKDGATLGTESHPRIR-LD 549
P +D V+ ++ V + P TI+ W K L + I+ D
Sbjct: 16042 DPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQ--WIKGDQELSNTARLEIKSTD 16099
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAIN 609
SL + D G Y + + G S + +++V P PE PV +S V
Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVV-ISGVTAEKCT 16158
Query: 610 LTWTKPF-DGNSPLIRYILEMSENNA-PWTVLLASVDPKATSVTVKGLVPARSYQFRLCA 667
L W P DG S +I YI+E E + WTV+ A+V + VT L+ Y FR+ A
Sbjct: 16159 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTK--LLEGNEYTFRIMA 16216
Query: 668 VNDVGKGQFSKDTERVSL-PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGY 726
VN G G+ + V+ P P AP + + T S+++ W+ P + IL GY
Sbjct: 16217 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV-TKDSMIVVWERPASDGGSEIL-GY 16274
Query: 727 IIRYCLAGLPVGYQFKNITDADVNNLLLE--DLIIWTNYEIEVAAYNSAGLGVYS--SKV 782
++ G ++ + L L LI +YE V+A N+AGL S S
Sbjct: 16275 VLE---KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAY 16331
Query: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN-QGYKLIAWEPEQEEEVT 841
+ PP N +++ +W+ P + G QGY ++ E T
Sbjct: 16332 QKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI--YDGGCEIQGY-IVEKCDVSVGEWT 16388
Query: 842 MVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPV--- 898
M T P + ++ L+K EY + G G H DVPGP+
Sbjct: 16389 MCTP-PTGINKTNIEVEKLLEKH-EYNFRICAINKAGVGE---------HADVPGPIIVE 16437
Query: 899 GHLSFSEI-LDTSLK--VSWQEPGEKNGI--LTGYRISWEEYNRTNTRVTHY-LPNVTLE 952
L +I LD L+ ++ + G + G ++ + + + + +VT
Sbjct: 16438 EKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 16497
Query: 953 YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQ 1012
+ L + Y +T + ++ ++ V + P PP NL ++ I SV++
Sbjct: 16498 FTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL-DTPSPPVNLKVTEITKDSVSIT 16556
Query: 1013 FRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRM 1071
+ P DG + I ++VE + E ++N S ++ L Y FR+
Sbjct: 16557 WEPPLLDGGSKIKNYIVEKR-----EATRKSYAAVVTN-CHKNSWKIDQLQEGCSYYFRV 16610
Query: 1072 RQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPES 1131
N G P+Q + I+ + P P +++ + S+ L W + E++G +
Sbjct: 16611 TAENEYGIGLPAQTADPIKVAEVP--QPPGKITVDDVTRNSVSLSWT---KPEHDGGSKI 16665
Query: 1132 VGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTV 1190
+ Y ++ H + S + + I +L + EY +V A N G S P S V
Sbjct: 16666 IQYIVEMQAK--HSEKWSECARVK-SLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAV 16722
Query: 1191 VGRTRESV--PSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQP 1248
++ V P P S + + EVP + R + + D P
Sbjct: 16723 PIVAKDLVIEPDVKPAFSSYSVQVGQDLKI---EVPISGRPKPTITWT-------KDGLP 16772
Query: 1249 RFWLVEGNSSRSAQLTGL----------GKYVLYEVQVLAFTRIGDGSPSHPPILERTLD 1298
N + S LT L G+Y + V +G + S +E
Sbjct: 16773 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV-----VGQKTAS----IEIVTL 16823
Query: 1299 DVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA 1357
D P PP G + F +V S+ L W PP G + I + +TTT T V A A
Sbjct: 16824 DKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTT--TVWDVVSATVA 16881
Query: 1358 R-QYTATGLKPESVYLFRITAQTRKGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
R T LK + Y FRI A+ R G A E+ +V P PP P +
Sbjct: 16882 RTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATA--ISK 16939
Query: 1416 RSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S+++ W EP ++G SPV Y ++ +E S W + ++ H+ + F L+ Y+F
Sbjct: 16940 DSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHD-TQFKAQNLEEGIEYEF 16998
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAA-PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV A N +G + S+ SE P P + V + T ++W P D +
Sbjct: 16999 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEIT---LQWTKPVYDG-GSM 17054
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
+ G+ + R+L P W + S N+ TQ+ + L + +
Sbjct: 17055 ITGYIVEKRDL---------------PDGRWMKA----SFTNVIE---TQFTVSGLTEDQ 17092
Query: 1594 RYEIRMSVYNAVG--------EGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT---QLDV 1642
RYE R+ NA G GP + EV + R+ +V A T + DV
Sbjct: 17093 RYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADV 17152
Query: 1643 TWEP-PPLDSQNGDIQGYKIYFWEAQRGNLTER-VKTLFLAENSVKLKNLTGYTAYMVSV 1700
+P P ++ GD + E+ R + K L + ++++++ +
Sbjct: 17153 HGKPLPTIEWLRGDKE-----IEESARCEIKNTDFKALLIVKDAIRI------DGGQYIL 17201
Query: 1701 AAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLV 1760
A N AG +S P + V+ + +T+ +++W +P +G + V
Sbjct: 17202 RASNVAGS--KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPLQDGGSDISHYV 17258
Query: 1761 YEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIE-ANVTT 1818
E +V +V NS LKV L EG Y FRI A + G +E A V
Sbjct: 17259 VEKRETSRLAWTVVASEVVTNS---LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLM 17315
Query: 1819 GPGEGAPGPP-GVPIIVRYSSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDI 1876
PGPP + + ++ + W+ D G I Y++E R W IK
Sbjct: 17316 KNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW---IKCN 17372
Query: 1877 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
+ ++ + L Y+FRV A N G G PS
Sbjct: 17373 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17408
Score = 190 bits (482), Expect = 1e-47
Identities = 360/1569 (22%), Positives = 576/1569 (36%), Gaps = 242/1569 (15%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAG 471
TV G + L +G P P ITW K + IL P +S ++ I + SD G
Sbjct: 7204 TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS-TVTIVDSKRSDTG 7262
Query: 472 TYTCLATNSRGVDEASADLVVWAR---------TRITK--------PPQDQSVIKGTQAS 514
TY A N G A ++ V + T +T PP+D S
Sbjct: 7263 TYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDG------GS 7316
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA 574
+ + R T +W K +T+ + +L N Y RV +
Sbjct: 7317 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKE-------------YIFRVAAE 7363
Query: 575 ---GGNDSRSAHLRVRQLPHAPEHPVATL--STVERRAINLTWTKPFD-GNSPLIRYILE 628
G + A + P P L S + + A+ LTW +P D G SP+ Y +E
Sbjct: 7364 NMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE 7423
Query: 629 MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL--P 686
+ + V + K T+ VKGL + Y+FR+ A N G G+ SK TE + + P
Sbjct: 7424 RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP 7483
Query: 687 EEPPTAPPQNVIAS-GRTNQSIMIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNI 744
+PP P + + G+T S+ + W P H G ++ Y+I G +
Sbjct: 7484 IDPPWPPGKPTVKDVGKT--SVRLNWTKP--EHDGGAKIESYVIEMLKTGTDEWVRVAE- 7538
Query: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEA 802
LL L+ Y V A N AG S S + P PP +
Sbjct: 7539 -GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7597
Query: 803 TNSTTIRFTWNAPSPQFINGI------NQGYKLIAWEP-EQEEEVTMVTARPNFQDSIHV 855
T W P + I + + W+ + + T T P + S++V
Sbjct: 7598 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYV 7657
Query: 856 GFVS-----GLKKFTEYFTSVLC---FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
V+ G +TE SVL FTT PGP L+ ++
Sbjct: 7658 FRVAAENAIGQSDYTEIEDSVLAKDTFTT------------------PGPPYALAVVDVT 7699
Query: 908 DTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTI 966
+ + W+ P G + Y I +E T +RVT + T
Sbjct: 7700 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 7759
Query: 967 EVAAMTSKGQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSI 1023
+V A G G S T +S P P PP +L +++ G + + + ++ P +G + I
Sbjct: 7760 QVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 7819
Query: 1024 SRWLVE-AQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
+ VE VG E+W+ ++ + D + + P Y R+R VN +G S P
Sbjct: 7820 IGYHVEMCPVGT----EKWMRVNSRPIK-DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7874
Query: 1083 SQPSRKIQTLQAPPDMAPANVSLRTAS---------ETSLWLRWMPLPEMEYNGNPESVG 1133
S+ S + + PD P + L T + R +P+P + ++ + + V
Sbjct: 7875 SEISENV--VAKDPDCKP-TIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK 7931
Query: 1134 YKIKYSRSDGHGKTLSHV-VQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVG 1192
+ + + H +H+ V V D I Y + ++ N +GS S V
Sbjct: 7932 ASDRLTMKNDH--ISAHLEVPKSVRADAGI--------YTITLE--NKLGSATASINV-- 7977
Query: 1193 RTRESVPSSGP-TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW 1251
+ + GP ++ A T SS + W E PE D +L Y + + +++ +
Sbjct: 7978 ---KVIGLPGPCKDIKASDITKSSCKLTW-EPPEFDGGTPILHY--VLERREAGRRTYIP 8031
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILF 1309
++ G + S + L Y +V A ++G G P++ + P PP+ +
Sbjct: 8032 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8091
Query: 1310 PEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPE 1368
++ + W+PP G I+ Y I E L P YTA GL+
Sbjct: 8092 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEG 8150
Query: 1369 SVYLFRITAQTRKGWGEAAEALVVT--TEKRDRPQPPSRPM--VQQEDVRARSVLLS--- 1421
Y FR+ A+ G E + A T + D P+ R V++ D A +S
Sbjct: 8151 KEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSP 8210
Query: 1422 -----WEPGSDGLSPV------------RYYTIQTRE---LPSGRWALHSASVSHNASSF 1461
W + + P R +Q E LP + S +
Sbjct: 8211 YPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLR 8270
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH-TTTSVLI 1520
+ D L+P + +K ND G +++ T+ P I V TSVL
Sbjct: 8271 VRDSLRPDHGL-YMIKVENDHG------IAKAPCTVSVLDTPGPPINFVFEDIRKTSVLC 8323
Query: 1521 RWQPPAEDKINGILLGFRIRYRELLYEGLRGFTL--RGINNPGATWAELTSMYSMRNLSR 1578
+W+PP +D + I+ +TL + P + W +TS ++R+
Sbjct: 8324 KWEPPLDDGGSEII----------------NYTLEKKDKTKPDSEWIVVTS--TLRH--- 8362
Query: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV-PTAAPRNVVVHGATA 1637
+Y + L + + Y R+ N G GP + + + P AP +V T+
Sbjct: 8363 ---CKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS 8419
Query: 1638 TQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQRGNLT--ERVKTLFLAENSVKLKNLTGYT 1694
+ V W P NG I G Y+ E + N T RV L + L
Sbjct: 8420 NSMLVKWNEP---KDNGSPILG---YWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 8473
Query: 1695 AYMVSVAAFNAAGDGPRSTPTQGQT--QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNG 1752
Y+ V A NAAG G S P+ +T +P P + ++ ++T++ + WE P F G
Sbjct: 8474 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGG 8533
Query: 1753 ILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEI 1812
G + Y + G ++ K VK++ EG Y+ R+ A
Sbjct: 8534 ---GEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSA--------- 8581
Query: 1813 EANVTTGPGEGAPG------------PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860
GEG PG PP V + V I I GK V+
Sbjct: 8582 ----VNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIM-----AGKTLRIPAVVT 8632
Query: 1861 ARPSDEGLW 1869
RP +W
Sbjct: 8633 GRPVPTKVW 8641
Score = 189 bits (481), Expect = 2e-47
Identities = 331/1484 (22%), Positives = 562/1484 (37%), Gaps = 198/1484 (13%)
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTY 473
G S+ L G P P + W K G ++ + S SL++ + D+G Y
Sbjct: 16460 GGSLRLFVPIKGRPTPEVKWGK-----VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKY 16514
Query: 474 TCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTI------ 527
T NS G A + V PP + V + T+ S+ +T +P +
Sbjct: 16515 TLTLENSSGTKSAFVTVRV---LDTPSPPVNLKVTEITKDSV--SITWEPPLLDGGSKIK 16569
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAG----GNDSRSAH 583
YI EK AT + + +N S I Q G +Y RV + G +++A
Sbjct: 16570 NYIVEKREATRKSYAAVVTNCHKN-SWKIDQLQEGC--SYYFRVTAENEYGIGLPAQTAD 16626
Query: 584 -LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
++V ++P P T+ V R +++L+WTKP DG S +I+YI+EM ++ A
Sbjct: 16627 PIKVAEVPQPPGK--ITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16684
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ--------FSKDTERVSLPEEPPTAP 693
V K+ + L Y FR+ AVN+ G+ +KD V P+ P
Sbjct: 16685 RV--KSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL--VIEPDVKPAFS 16740
Query: 694 PQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK-NITDADVNNL 752
+V + I +P P I + GLP+ + N+TD+ L
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPT-----------ITWTKDGLPLKQTTRINVTDS----L 16785
Query: 753 LLEDLIIWTNYEIEVAAYNSAGLGVYSSKVT--EWTLQGVPTVPPGNVHAEATNSTTIRF 810
L L I ++ + Y V K E P P G V + ++ +I
Sbjct: 16786 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITL 16845
Query: 811 TWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTS 870
+WN P G ++ + ++ + T V + + V+ LK TEY
Sbjct: 16846 SWNPPL------YTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFR 16899
Query: 871 VLCFTTPGDG--PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTG 927
+ G S P + + PGP G + I S+ + W EP G + G
Sbjct: 16900 IFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 16959
Query: 928 YRISWEEYN-----RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAS 982
Y + +E N + N + H +++ L Y V A G G+ S +
Sbjct: 16960 YHLERKERNSILWTKVNKTIIH-----DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17014
Query: 983 T--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGE 1039
+ + P + PG P + + +TLQ+ +P YDG + I+ ++VE + G
Sbjct: 17015 SECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWM 17071
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
+ + + + V L Y FR+ N G S+PS + A ++
Sbjct: 17072 KASFTNVIETQ-----FTVSGLTEDQRYEFRVIAKNAAGAI--SKPSDSTGPITAKDEVE 17124
Query: 1100 PANVSLR---------TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKT 1147
+S+ A ET + PLP +E+ + + + + K
Sbjct: 17125 LPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKA 17184
Query: 1148 LSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVS 1207
L +V+D + D + ++A N GS + V R P GP V+
Sbjct: 17185 LL-IVKDAIRIDGG----------QYILRASNVAGSKSFPVNVKVLDRPG-PPEGPVQVT 17232
Query: 1208 ALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNS--SRSAQLTG 1265
+ TS + WS P G + + V+ K +T W V + + S ++T
Sbjct: 17233 GV--TSEKCSLTWS--PPLQDGGSDISHYVVEKR---ETSRLAWTVVASEVVTNSLKVTK 17285
Query: 1266 LGKYVLYEVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
L + Y +++A + G G P P+L + +PGPP + + S+ + W P
Sbjct: 17286 LLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRP 17345
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
+ G + I + + + + + TGL + Y FR++A+ G G
Sbjct: 17346 DSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 17405
Query: 1385 EAAEALVV--TTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRE 1441
E + A V + +P PP+ + D S+ L+W +P DG S + Y ++ +
Sbjct: 17406 EPSPATVYYKACDPVFKPGPPTNAHIV--DTTKNSITLAWGKPIYDGGSEILGYVVEICK 17463
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
W + + + F + +L YK RV A N +G E + S T
Sbjct: 17464 ADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTVKPEDK 17521
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
EAP L + +++R A I +G P
Sbjct: 17522 LEAPE-LDLDSELRKGIVVRAGGSARIHI----------------------PFKGRPTPE 17558
Query: 1562 ATWAELTSMYS--MRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG 1619
TW+ ++ ++ + TQ +DN +++ + + + N+ G S V V
Sbjct: 17559 ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG----SKSAFVTVK 17614
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR---GNLTERVK 1676
P+N+ V + WEPP +D ++ Y I E+ R N++ +
Sbjct: 17615 VLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDG-GAKVKNYVIDKRESTRKAYANVSSK-- 17671
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELT 1736
++ S K++NLT Y V A N G G PS P V ++++
Sbjct: 17672 ---CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17728
Query: 1737 TTSVNVSWEAPQFPNGI-LEGYRLVYEPCS----PVDGVSKIVTVDVKGNSPLWLKVKDL 1791
TS ++ WE P+ G + GY + +P + SK+ V G L
Sbjct: 17729 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTG----------L 17778
Query: 1792 AEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
+ G Y+FR++A Y + G+ P GVP+I +
Sbjct: 17779 SSGQEYQFRVKA----YNEK---------GKSDPRVLGVPVIAK 17809
Score = 189 bits (479), Expect = 3e-47
Identities = 429/1885 (22%), Positives = 716/1885 (37%), Gaps = 273/1885 (14%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAGR 180
V GE I P + P P V+W +DG+++ S R+ + ++ L + +V DAG
Sbjct: 7901 VIEGEKLSIPVP-FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGI 7959
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN 240
Y + N K G S I + V + GP I K + + + ++T E
Sbjct: 7960 YTITLEN-KLGSATAS--INVKVIGLPGPCKDI--------KASDITKSSCKLTWEPPEF 8008
Query: 241 ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVL-------RSSSV 293
LH + ++ + RR IP +G + + + ++ R +V
Sbjct: 8009 DGGTPILHYVLER---------REAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8059
Query: 294 PSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW----YKDAAVV 349
V G Y+ L+ P ++P++ + VD+ +ITW Y + +
Sbjct: 8060 NKVGGGEYIE-LKNPVIAQDPKQ----PPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8114
Query: 350 E---VEKLTRFRQR----NDGGLQI-----SGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
+EK+ + +R N+ + I GL F+ A NAAG + S
Sbjct: 8115 MGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPP 8174
Query: 398 TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLES 457
T I D V+L R ++ ++G+ I S+ S
Sbjct: 8175 TKAVDPI----------DAPKVIL--------RTSLEVKRGDEIALDASI---------S 8207
Query: 458 GSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVC 517
GS + T I D + + +A LV + + + ++ V+ TQ
Sbjct: 8208 GSPYPTITWIKDENVIV-----PEEIKKRAAPLVRRRKGEVQE--EEPFVLPLTQ----- 8255
Query: 518 GVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGN 577
R++I D + G ES R+R + D G Y +V + G
Sbjct: 8256 ------RLSI------DNSKKG-ESQLRVR----------DSLRPDHGLYMIKVENDHGI 8292
Query: 578 DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP- 635
+ V P P + V + + ++ W P D G S +I Y LE + P
Sbjct: 8293 AKAPCTVSVLDTPGPPINFV--FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPD 8350
Query: 636 --WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL-PEEPPTA 692
W V+ +++ SVT L+ + Y FR+ A N G G V+ P PP A
Sbjct: 8351 SEWIVVTSTLRHCKYSVTK--LIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8408
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNL 752
P + ++ +N S++++W P + NG I+ Y L V + + + N
Sbjct: 8409 PDKPIVEDVTSN-SMLVKWNEPKD---NG---SPILGYWLEKREVNSTHWSRVNKSLLNA 8461
Query: 753 L---LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV--HAEATNSTT 807
L ++ L+ Y V A N+AG G +S T P PPG T+STT
Sbjct: 8462 LKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTT 8520
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTAR-PNFQDSIHVGFVSGLKKFTE 866
I W P+ N G +++ + +++ T +R + V +++ +
Sbjct: 8521 IELEWEPPA------FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGAD 8574
Query: 867 YFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKN---- 922
Y V G+GP Q V E P L D S+K Q K
Sbjct: 8575 YKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVEL------DVSVKGGIQIMAGKTLRIP 8628
Query: 923 GILTGYRIS---W--EEYNRTNTRVTHYLPNVTLEYRVTGLTALTT-YTIEVAAMTSKGQ 976
++TG + W EE RV + NV + + AL + V T+
Sbjct: 8629 AVVTGRPVPTKVWTKEEGELDKDRVV--IDNVGTKSELIIKDALRKDHGRYVITATNSCG 8686
Query: 977 GQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVV 1035
+ +A+ + ++PGP +L + L + P DG + I+ +++E + +
Sbjct: 8687 SKFAAARVEVF---DVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 8743
Query: 1036 GEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP 1095
+ + E + ++ L Y FR+ N G PP + +
Sbjct: 8744 HTWRQPI-------ETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLG 8796
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
P +P ++ +++++ L W E NG GY I+ R H K V R
Sbjct: 8797 PPTSPERLTYTERTKSTITLDWK---EPRSNGGSPIQGYIIEKRR---HDKPDFERVNKR 8850
Query: 1156 V--ERDYTIEDLEEWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGPTNVSALATT 1212
+ + +E+L+E Y +V+A N IG S P V + VP PT L+
Sbjct: 8851 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP---PTIKLRLSVR 8907
Query: 1213 SSSMLVRWSE---VPEADRNGLVLGYKVMYKEKDSDTQPR--FWLVEGNSSRSAQLTGLG 1267
++ V+ E +P AD GL + K + +P + + SRS T L
Sbjct: 8908 GDTIKVKAGEPVHIP-ADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 8966
Query: 1268 --KYVLYE---VQVLAFTRIGDGSPS-HPPILERTLDDVPGPPMGILFPEVRTTSVRLIW 1321
K V + V A R+G + H + +R P PP + +++ S L W
Sbjct: 8967 IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDR-----PSPPRNLAVTDIKAESCYLTW 9021
Query: 1322 QPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA-RQYTATGLKPESVYLFRITAQTR 1380
P G + + + + + + EV + ++Y L P Y FR+ A +
Sbjct: 9022 DAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNK 9081
Query: 1381 KGWGEAAEA-LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQ 1438
G + ++ VV + P PP +P V S+L+SW P D G SP+ Y ++
Sbjct: 9082 YGISDECKSDKVVIQDPYRLPGPPGKPKVLART--KGSMLVSWTPPLDNGGSPITGYWLE 9139
Query: 1439 TRELPSGRWALHSAS----VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESE-S 1493
RE S W+ S + V F V RL Y+FR A N G SE S+
Sbjct: 9140 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPE 9199
Query: 1494 LTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT 1553
+ P P+ V T +S+ + W+PPA+D + I G+ + +E EG +
Sbjct: 9200 VAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIK-GYIVEMQE---EGTTDW- 9254
Query: 1554 LRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSP 1612
+ +N P + + NL + R+Y R+ N GE PS
Sbjct: 9255 -KRVNEPDKLITTCECV---------------VPNLKELRKYRFRVKAVNEAGESEPSDT 9298
Query: 1613 PQEVFVGEA-------VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
E+ + + A +V + ++ + P + + G +
Sbjct: 9299 TGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMK 9358
Query: 1666 AQRGNLTERVKTLFLAENSVKL------KNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQT 1719
++ E + L AENS + ++ TG S+ A N AG + T
Sbjct: 9359 DGVHDIPEDAQ-LETAENSSVIIIPECKRSHTG----KYSITAKNKAG---QKTANCRVK 9410
Query: 1720 QQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDV 1778
P P +K S++T S +SW+ P G ++GY + +DG +
Sbjct: 9411 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT---IDGKAWTKVNPD 9467
Query: 1779 KGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEA-NVTTGPGEGAPGPPGVPIIVRY 1836
G++ V DL Y FR+RA+ F GP +E TT P P + + +
Sbjct: 9468 CGSTTF--VVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9525
Query: 1837 SSAIAIHWSSGDP---GKGPITRYVIEARPSD-----EGLWDILIKDIPKEVSSYTFSMD 1888
+ +H S P G P+T Y++E D + W K ++V F+++
Sbjct: 9526 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK---RDVEELQFTVE 9582
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSS 1913
L G Y+FRV AVN G PS+
Sbjct: 9583 DLVEGGEYEFRVKAVNAAGVSKPSA 9607
Score = 187 bits (474), Expect = 1e-46
Identities = 315/1447 (21%), Positives = 553/1447 (38%), Gaps = 151/1447 (10%)
Query: 524 RVTIRYIWEKDGATLGTESHPRIRLDRNGSL-HISQTWSGDIGTYTCRVISAGGNDSRSA 582
R T W KD L + N SL I D+G Y ++ ++ G +
Sbjct: 15677 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL 15736
Query: 583 HLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAP-WTVLL 640
++ V P P PV + V +I L+W P +DG S + YI+E + + W ++
Sbjct: 15737 NVIVLDKPGPPTGPVK-MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15795
Query: 641 ASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIAS 700
A+V T++ L YQFR+ A N GK + V+ PP + +
Sbjct: 15796 ATV--ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 15853
Query: 701 GRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIW 760
+ S+ +QW P + ++ ++ R + + N T L
Sbjct: 15854 LSSRDSMEVQWNEPISDGGSRVIGYHLERK--ERNSILWVKLNKTPIPQTKFKTTGLEEG 15911
Query: 761 TNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFI 820
YE V+A N G+G SKV+E + P PPG A ++ W P+
Sbjct: 15912 VEYEFRVSAENIVGIGK-PSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPT---- 15966
Query: 821 NGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG- 878
+ G K+ + E++E + +F + I F V+GL + Y V+ G
Sbjct: 15967 --YDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGV 16024
Query: 879 -DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNR 937
P + + ++V P +S ++ V E + + + G I ++ +
Sbjct: 16025 FSEPSESTGAITARDEVDPP--RISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK 16082
Query: 938 TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL----- 992
+ +++ T + T+ +++ A G + A ++ +
Sbjct: 16083 GDQELSN-----TARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 16137
Query: 993 --PGPPTN-LGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQVGVVGEGEEWLLIHQLS 1048
PGPP + IS + TL ++P DG + I ++VE + L+ +
Sbjct: 16138 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRE------TSRLVWTVVD 16191
Query: 1049 NEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTA 1108
S +V L Y+FR+ VN G P + + AP + T
Sbjct: 16192 ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTV 16251
Query: 1109 SETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLE 1166
++ S+ + W +G E +GY ++ +G T H R+ E + L
Sbjct: 16252 TKDSMIVVW---ERPASDGGSEILGYVLEKRDKEGIRWTRCH---KRLIGELRLRVTGLI 16305
Query: 1167 EWTEYRVQVQAFNAIG-SGPWSQTVVGRTRESVPSSGP-TNVSALATTSSSMLVRWSEVP 1224
E +Y +V A NA G S P + + + + GP N + T SS+ + WS+ P
Sbjct: 16306 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK-P 16364
Query: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLV----EGNSSRSAQLTGLGKYVLYEVQVLAFT 1280
D + GY V + D W + G + + ++ L + Y ++ A
Sbjct: 16365 IYDGGCEIQGYIV----EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16420
Query: 1281 RIGDGSPSHPP---ILERTLDDVPGPPMGILFPEVRTT----SVRLIWQPPAAPNGIILA 1333
+ G G + P I+E L+ P + + ++ S+RL P +
Sbjct: 16421 KAGVGEHADVPGPIIVEEKLE-APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 16479
Query: 1334 YQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY---LFRITAQTRKGWGEAAEAL 1390
++ + + A ++V + +T+ L + Y + +T + G ++
Sbjct: 16480 GKVDGEIR----DAAIIDVTS----SFTSLVLDNVNRYDSGKYTLTLENSSG----TKSA 16527
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
VT D P PP V + + SV ++WEP DG S ++ Y ++ RE +A
Sbjct: 16528 FVTVRVLDTPSPPVNLKVTE--ITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16585
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
+ N S+ +D+L+ SY FRV A N+ G ++ ++ + + + P ++
Sbjct: 16586 VVTNCHKN--SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVP--QPPGKIT 16641
Query: 1510 VTPHTTTSVLIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE 1566
V T SV + W P D KI ++ + ++ E W+E
Sbjct: 16642 VDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-------------------KWSE 16682
Query: 1567 LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-------PSSPPQEVFVG 1619
+ S+ Q + NL + Y R+ N G P V
Sbjct: 16683 CARVKSL---------QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 16733
Query: 1620 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF 1679
+ P + +V V ++ ++ P P + D K + R N+T+ +L
Sbjct: 16734 DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK----QTTRINVTD---SLD 16786
Query: 1680 LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTS 1739
L S+K + Y ++VA N G S + P P VKF +++ S
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVA--NVVGQKTASIEIVTLDKPDPPKGP--VKFDDVSAES 16842
Query: 1740 VNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1799
+ +SW P + G + + + V +V+ V + LKV L G Y+F
Sbjct: 16843 ITLSWNPPLYTGGC-QITNYIVQKRDTTTTVWDVVSATVARTT---LKVTKLKTGTEYQF 16898
Query: 1800 RIRAKTF---TYGPEIEANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPGKGPI 1854
RI A+ ++ E + V P + PGPPG P S ++ I W + G P+
Sbjct: 16899 RIFAENRYGQSFALESDPIVAQYPYK-EPGPPGTPFATAISKDSMVIQWHEPVNNGGSPV 16957
Query: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSP 1914
Y +E + + LW + K I + F L+ G+ Y+FRV A N G G S
Sbjct: 16958 IGYHLERKERNSILWTKVNKTI---IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17014
Query: 1915 SQSVPAQ 1921
S+ A+
Sbjct: 17015 SECYVAR 17021
Score = 177 bits (449), Expect = 1e-43
Identities = 352/1605 (21%), Positives = 600/1605 (37%), Gaps = 162/1605 (10%)
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP-------LDSTVI--DGM 417
+SGL D F+ A+NAAG + + + + P TVI G
Sbjct: 14921 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 14980
Query: 418 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
+ L + SG P P + W K + L G+ +L S +L+ + D+G YT A
Sbjct: 14981 AFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 15039
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP-------RVTIRYI 530
TN G + ++ V R PP+ + S C ++ P ++ +
Sbjct: 15040 TNPGGFAKHIFNVKVLDRPG---PPEGPLAVTEV-TSEKCVLSWFPPLDDGGAKIDHYIV 15095
Query: 531 WEKDGATLG-TESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA---GGNDSRSAHLRV 586
+++ + L T +++ + L +++ G+ Y RV++ G + + +
Sbjct: 15096 QKRETSRLAWTNVASEVQVTK---LKVTKLLKGN--EYIFRVMAVNKYGVGEPLESEPVL 15150
Query: 587 RQLPHAPEHPVAT--LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
P+ P P ++T+ + ++ + W P DG S +I YI+E + +
Sbjct: 15151 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15210
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVG------KGQFSKDTERVSLPEEPPTAPPQNV 697
V GL Y+FR+ A N G F K + V P PP N
Sbjct: 15211 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKP-----GPPGNP 15265
Query: 698 IASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA---DVNNLLL 754
+ SI I W P + I GY++ L P +++ +T + +
Sbjct: 15266 RVLDTSRSSISIAWNKPIYDGGSEIT-GYMVEIAL---PEEDEWQIVTPPAGLKATSYTI 15321
Query: 755 EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814
L Y+I + A NS GLG + T + + P + +A +
Sbjct: 15322 TGLTENQEYKIRIYAMNSEGLG--EPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACC 15379
Query: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT--EYFTSVL 872
F+ + + W + E + + ++ + V + +F +Y +V
Sbjct: 15380 TLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI--VGNVNRFDSGKYILTV- 15436
Query: 873 CFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS 931
G +S VR D PGP L E+ TS+ ++W P G + Y +
Sbjct: 15437 ---ENSSGSKSAFVNVRVL-DTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE 15492
Query: 932 WEEYNR-------TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
E R TN T ++V L +Y V A G G + A T
Sbjct: 15493 KRESTRKAYSTVATNCHKT--------SWKVDQLQEGCSYYFRVLAENEYGIG-LPAETA 15543
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
S E P PP + + ++ SV+L + +P +DG + I ++VE Q ++W
Sbjct: 15544 ESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQ---TKGSDKWAT 15600
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPA 1101
+ + L YSFR+ N G S P Q S + + L PP
Sbjct: 15601 CATVK----VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLL 15656
Query: 1102 NVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD-- 1159
+ + L + ++ + G P + + + + K + V + E +
Sbjct: 15657 FNTFTVLAGEDLKV------DVPFIGRPTPA---VTWHKDNVPLKQTTRVNAESTENNSL 15707
Query: 1160 YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR 1219
TI+D V+ N+ G + V+ + P +GP + + T+ S+ +
Sbjct: 15708 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG-PPTGPVKMDEV--TADSITLS 15764
Query: 1220 WSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYVLYEVQVLA 1278
W P+ D + Y V EK + + +V +R+ + L Y+ ++ A
Sbjct: 15765 WGP-PKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAA 15820
Query: 1279 FTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQ 1335
R G + S P + + VPGPP + S+ + W P + G ++ Y
Sbjct: 15821 ENRYGKSTYLNSEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYH 15879
Query: 1336 ITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTE 1395
+ + + + P + + TGL+ Y FR++A+ G G+ ++
Sbjct: 15880 LERKERNSILWVKLNKTPIPQTK-FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYV- 15937
Query: 1396 KRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASV 1454
RD PP RP + V SV L W +P DG S + Y ++ +ELP GRW + ++
Sbjct: 15938 ARDPCDPPGRP--EAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRW-MKASFT 15994
Query: 1455 SHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHT 1514
+ + F V L Y+FRV A N G FSE SES + A + P +S+ P
Sbjct: 15995 NIIDTHFEVTGLVEDHRYEFRVIARNAAG--VFSEPSESTGAITARDEVDPPRISMDPKY 16052
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG-FTLRGINNPGATWAELTSMYSM 1573
++++ K++ + G I + ++G L + + S+
Sbjct: 16053 KDTIVV--HAGESFKVDADIYGKPIP----TIQWIKGDQELSNTARLEIKSTDFATSLSV 16106
Query: 1574 RNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVH 1633
++ R Y L N + ++V GP P VV+
Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGP----------------VVIS 16150
Query: 1634 GATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGY 1693
G TA + + W+ PPL DI Y + E R L V + S K+ L
Sbjct: 16151 GVTAEKCTLAWK-PPLQDGGSDIINYIVERRETSR--LVWTVVDANVQTLSCKVTKLLEG 16207
Query: 1694 TAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPN 1751
Y + A N G G S P + P AP + + + +T S+ V WE P
Sbjct: 16208 NEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDG 16267
Query: 1752 GI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT--- 1807
G + GY L + + + L L+V L E Y FR+ A+
Sbjct: 16268 GSEILGYVLEKRDKEGI----RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLS 16323
Query: 1808 -YGPEIEANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSG-DPGKGPITRYVIEARPS 1864
P P PGPP P ++ + S++ + WS G I Y++E
Sbjct: 16324 EPSPPSAYQKACDP-IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 16382
Query: 1865 DEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G W + P ++ ++ L Y+FR+ A+N G G
Sbjct: 16383 SVGEWTMCTP--PTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16425
Score = 177 bits (449), Expect = 1e-43
Identities = 292/1333 (21%), Positives = 502/1333 (37%), Gaps = 167/1333 (12%)
Query: 647 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGR-TNQ 705
+T++ K S + L A N G F+K V + + P PP+ +A T++
Sbjct: 15019 STNLVNKDSTRRDSGAYTLTATNP---GGFAKHIFNVKVLDRP--GPPEGPLAVTEVTSE 15073
Query: 706 SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNNLLLEDLIIWTNYE 764
++ W PP + + YI++ + N+ ++ V L + L+ Y
Sbjct: 15074 KCVLSWFPPLDDG-GAKIDHYIVQKRETSR---LAWTNVASEVQVTKLKVTKLLKGNEYI 15129
Query: 765 IEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFING 822
V A N G+G + S V G P PP N ++ W P
Sbjct: 15130 FRVMAVNKYGVGEPLESEPVLAVNPYGPPD-PPKNPEVTTITKDSMVVCWGHPDS----- 15183
Query: 823 INQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-DG 880
+ G ++I + E+ ++ + N + + + VSGL + EY ++ G
Sbjct: 15184 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15242
Query: 881 PRSTPQLVRTHEDV--PGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNR 937
P T + + V PGP G+ + +S+ ++W +P G +TGY +
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15302
Query: 938 TNTRVTHYLPNVTLE---YRVTGLTALTTYTIEVAAMTSKGQGQVSA-----STISSGVP 989
++ P L+ Y +TGLT Y I + AM S+G G+ + +P
Sbjct: 15303 DEWQIV--TPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 15360
Query: 990 PELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
PE+ + I F P +W + GE + I S+
Sbjct: 15361 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH-----GESLDKASIESTSS 15415
Query: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
+ V ++N F + + N G+ R + T P D+ ++ +
Sbjct: 15416 YT---LLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDL-----KVKEVT 15467
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
+TS+ L W P P ++ G + Y ++ + + K S V + + + ++ L+E
Sbjct: 15468 KTSVTLTWDP-PLLD--GGSKIKNYIVE--KRESTRKAYSTVATNCHKTSWKVDQLQEGC 15522
Query: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSG----PTNVSALATTSSSMLVRWSEVPE 1225
Y +V A N G G + T ESV +S P ++ + T +S+ + W E PE
Sbjct: 15523 SYYFRVLAENEYGIG-----LPAETAESVKASERPLPPGKITLMDVTRNSVSLSW-EKPE 15576
Query: 1226 ADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDG 1285
D +LGY V + K SD V+ A +TGL + Y +V A G
Sbjct: 15577 HDGGSRILGYIVEMQTKGSDKWATCATVKVTE---ATITGLIQGEEYSFRVSAQNEKGIS 15633
Query: 1286 SPSH------------PP---ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
P PP +L T + G + + P + + + W P
Sbjct: 15634 DPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVP--- 15690
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
+ T R+N + ++ + + R+ Y+ ++T GEA E L
Sbjct: 15691 ---LKQTTRVNAESTENNSLLTIKDACREDVGH-------YVVKLTNSA----GEAIETL 15736
Query: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWAL 1449
V D+P PP+ P V+ ++V A S+ LSW P DG S + Y ++ R+ + W +
Sbjct: 15737 NVIV--LDKPGPPTGP-VKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQI 15793
Query: 1450 HSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILS 1509
SA+V+ ++ RLK Y+FR+ A N G S + ++ P
Sbjct: 15794 VSATVAR--TTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV 15851
Query: 1510 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1569
VT + S+ ++W P D + ++ G+ L W +L
Sbjct: 15852 VTLSSRDSMEVQWNEPISDGGSRVI----------------GYHLERKERNSILWVKL-- 15893
Query: 1570 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE--AVPTAAP 1627
N + T+++ L + YE R+S N VG G S E +V P P
Sbjct: 15894 -----NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRP 15948
Query: 1628 RNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKL 1687
++V T + + W+ P D I GY + E G + T + + ++
Sbjct: 15949 EAIIV---TRNSVTLQWKKPTYDG-GSKITGYIVEKKELPEGRWMKASFTNII-DTHFEV 16003
Query: 1688 KNLTGYTAYMVSVAAFNAAGDGPRSTPTQG----QTQQAAPSAPSSVKFSELTTTSVNVS 1743
L Y V A NAAG + + G + + P K+ + S
Sbjct: 16004 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 16063
Query: 1744 WEAPQFPNGILEGYRLVYEPCSPVDGV------SKIVTVDVKGNS-PLWLKVKDLAEGVT 1796
++ G +P + + S +++K L VKD +
Sbjct: 16064 FKVDADIYG---------KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16114
Query: 1797 YRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGKGP 1853
+ ++AK + NV PGPP P+++ +A + W G
Sbjct: 16115 GNYILKAKNVAGERSVTVNVKV---LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSD 16171
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSS 1913
I Y++E R + +W + + V + + + L G Y FR++AVN YG G
Sbjct: 16172 IINYIVERRETSRLVWTV----VDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG---E 16224
Query: 1914 PSQSVPAQKANPF 1926
P +S P NPF
Sbjct: 16225 PLESEPVVAKNPF 16237
Score = 171 bits (433), Expect = 7e-42
Identities = 352/1639 (21%), Positives = 604/1639 (36%), Gaps = 203/1639 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL--------DSTVIDGM 417
+++ L D F+ FARNAA V + I + P D V+
Sbjct: 19248 EVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAG 19307
Query: 418 SVV-LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
V+ + + +G P P I+W K + I + + L + D G Y
Sbjct: 19308 EVLKINADIAGRPLPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19366
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
N G + + V + PP I G A C ++ W +
Sbjct: 19367 LKNVAGTRSVAVNCKVLDKPG---PPAGPLEINGLTAEK-CSLS----------WGRPQE 19412
Query: 537 TLGTESHPRIRLDRNGSLHISQT-WSGDIGTYTCRVIS-----------------AGGND 578
G + I +++ + H++ T G++ +C+V G
Sbjct: 19413 DGGADIDYYI-VEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19471
Query: 579 SRSAHLRVRQLPHAPEHPVAT-LSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPW 636
S ++ P P + +++V + ++ L W++P DG S + YI+E E N+
Sbjct: 19472 LESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLR 19531
Query: 637 TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT------ERVSLPEEPP 690
V + V GL Y++R+ A N G S+ + + V LP PP
Sbjct: 19532 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPS-PP 19590
Query: 691 TAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
+ P ++ SG+T +I I W P + GY + Y K D D
Sbjct: 19591 SKP--KIVDSGKT--TITIAWVKPLFDG-GAPITGYTVEY-----------KKSDDTDWK 19634
Query: 751 NLL---------LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAE 801
+ + L Y V + N G S + P ++ +E
Sbjct: 19635 TSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 19694
Query: 802 ATNSTTIR----FTWNAPS-----PQFI-NGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851
+ ++ FT P P + + + + A+ + ++ N D
Sbjct: 19695 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRND 19754
Query: 852 SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
S K+T +VL ++ LV D PGP +++ ++ S
Sbjct: 19755 S---------GKYTLTIQNVLS--------AASLTLVVKVLDTPGPPTNITVQDVTKESA 19797
Query: 912 KVSWQEPGEKNGI-LTGYRISWEEYNRTN-TRVTHYLPNVTLEYRVTGLTALTTYTIEVA 969
+SW P G + Y I E ++ VT+ L Y+VT L Y V+
Sbjct: 19798 VLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNR--LSYKVTNLQEGAIYYFRVS 19855
Query: 970 AMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLV 1028
G G + A T E P PP LG+++I SV+L + +P +DG + I ++V
Sbjct: 19856 GENEFGVG-IPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVV 19914
Query: 1029 EAQVGVVGEGEE-WLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSR 1087
EA + +G++ W+ + V L + Y FR+ N G S P +
Sbjct: 19915 EA----LEKGQKNWVKCAVAKSTHHV----VSGLRENSEYFFRVFAENQAGLSDPRE--- 19963
Query: 1088 KIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY--NGNPESVGYKIKYSRSDGHG 1145
+ + + P + ++ ++++R +++ +G P K+ SR
Sbjct: 19964 LLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLP---KVTLSRDGVPL 20020
Query: 1146 KTLSHVVQDRVERDYTIEDLEEWTEY--RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP 1203
K + + TI E T R ++ A N+ G+ +V R P +GP
Sbjct: 20021 KATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG-PPTGP 20079
Query: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 1263
+S + T S+ ++W E P+ D V Y ++ +E + +
Sbjct: 20080 VVISDI--TEESVTLKW-EPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 20136
Query: 1264 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD-DVPGPPMGILFPEVRTTSVRLIWQ 1322
G+ Y+ ++ A R G + L PGPP V S+ + W
Sbjct: 20137 LTTGEE--YQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWH 20194
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
P + G + + + L + T + +Y FR+ A+ G
Sbjct: 20195 EPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAG 20254
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRE 1441
G+ + D +PP V+ D+ SV LSW+ P DG S + Y ++ R+
Sbjct: 20255 VGKPSHPSEPVLAI-DACEPPRN--VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRD 20311
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
LP GRW S + + + FI+ L + Y+FRV A N +G S SE + +
Sbjct: 20312 LPDGRWTKASFT-NVTETQFIISGLTQNSQYEFRVFARNAVGS--ISNPSEVVGPITCID 20368
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPG 1561
++ + P T V ++YR LR + G P
Sbjct: 20369 SYGGPVIDL-PLEYTEV--------------------VKYRAGTSVKLRA-GISGKPAPT 20406
Query: 1562 ATW------AELTSMYSMRNLSR-PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ 1614
W + ++ + N + S+ + D LN YE+++ NA+G ++
Sbjct: 20407 IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-YELKLR--NAMGSASATIRV 20463
Query: 1615 EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTER 1674
++ + + P P + TA ++ + W PP D G KI + ++ +
Sbjct: 20464 QI-LDKPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITHYIVEKRETSRV 20514
Query: 1675 VKTLF---LAENSVKLKNLTGYTAYMVSVAAFNAAGDGP--RSTPTQGQTQQAAPSAPSS 1729
V ++ L E + + Y+ V A N G G S + P P
Sbjct: 20515 VWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 20574
Query: 1730 VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV 1788
+ +++T S+ V W P G + GY L + G K++ ++ KV
Sbjct: 20575 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIRDTRQ---KV 20630
Query: 1789 KDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGPPGVPIIVRYS----SAIAIH 1843
L E Y++R+ A GP E + + PPG P +R + S+I +
Sbjct: 20631 TGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID-PPGPPAKIRIADSTKSSITLG 20689
Query: 1844 WSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1902
WS G +T YV+E R +E W + EV + + + LKPGV+Y FRV A
Sbjct: 20690 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTV--STKGEVRTTEYVVSNLKPGVNYYFRVSA 20747
Query: 1903 VNDYGFGTPSSPSQSVPAQ 1921
VN G G P ++ V A+
Sbjct: 20748 VNCAGQGEPIEMNEPVQAK 20766
Score = 167 bits (423), Expect = 1e-40
Identities = 305/1309 (23%), Positives = 495/1309 (37%), Gaps = 158/1309 (12%)
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+++ + P PE T ++ + +++LTW KP DG S ++ Y++E E V A
Sbjct: 19872 VKITEKPSPPEKLGVT--SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAV 19929
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPE--EPPTAPPQN---- 696
K+T V GL Y FR+ A N G + V + E EPP +N
Sbjct: 19930 A--KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 19987
Query: 697 ---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLL 753
V A I I +P P+ + G+P+ + T+ NL
Sbjct: 19988 TVYVRAGSNLKVDIPISGKPLPK-----------VTLSRDGVPLKATMRFNTEITAENLT 20036
Query: 754 --LEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
L++ + E+ A NS+G + G PT P V ++
Sbjct: 20037 INLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGP---VVISDITEESVTLK 20093
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEE----EVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W P +G +Q I + E EV+ AR + V L EY
Sbjct: 20094 WEPPK---YDGGSQVTNYILLKRETSTAVWTEVSATVARTMMK-------VMKLTTGEEY 20143
Query: 868 FTSVLCFTTPG--DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
+ G D S V+ PGP + + S+ V W EP G
Sbjct: 20144 QFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSA 20203
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
+ GY + ++ N + + L T ++VT ++A Y V A + G G+ S +
Sbjct: 20204 VVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPS- 20262
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ + PP N+ I++I SV+L ++ P +DG + I+ ++VE + G +
Sbjct: 20263 EPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTK--- 20319
Query: 1044 IHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQ---PSRKIQTLQAPPDMA 1099
+N + + + + L + Y FR+ N VG+ S PS+ P I + P
Sbjct: 20320 -ASFTNVTETQFI-ISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20377
Query: 1100 PANVS--LRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE 1157
P + ++ + TS+ LR +G P I++ + D +T + V +
Sbjct: 20378 PLEYTEVVKYRAGTSVKLR------AGISGKPAPT---IEWYKDDKELQTNALVCVENTT 20428
Query: 1158 --RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTV-VGRTRESVPSSGPTNVSALATTSS 1214
I+D + +++ NA+GS S T+ V + P GP +
Sbjct: 20429 DLASILIKDADRLNSGCYELKLRNAMGSA--SATIRVQILDKPGPPGGPIEFKTVTAEKI 20486
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTG--LGKYVLY 1272
++L R P AD G + + ++ K + S W + +T + K Y
Sbjct: 20487 TLLWR----PPADDGGAKITHYIVEKRETSRV---VWSMVSEHLEECIITTTKIIKGNEY 20539
Query: 1273 EVQVLAFTRIGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI- 1330
+V A + G G P ++ + PGPP ++ S+ ++W P A G
Sbjct: 20540 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 20599
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA- 1389
I Y + R + ++ RQ TGL S Y +R+ A G G +E
Sbjct: 20600 ISGYFLEKRDKKSLGWFKVLKETIRDTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPS 20658
Query: 1390 -LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRW 1447
+ D P PP++ ++ D S+ L W +P DG S V Y ++ R+ W
Sbjct: 20659 EFYKAADPIDPPGPPAK--IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEW 20716
Query: 1448 ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1507
S + ++V LKP +Y FRV A N G E E +E + EAP I
Sbjct: 20717 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL--EAPEI 20774
Query: 1508 LSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE- 1566
+ TSV+ + ED +L+ F +G P TW +
Sbjct: 20775 -DLDVALRTSVIAK---AGEDV--QVLIPF-----------------KGRPPPTVTWRKD 20811
Query: 1567 -----LTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEA 1621
+ YS+ N SL N +Y +++ N VGE P S V V +
Sbjct: 20812 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY--ILTIENGVGE-PKSSTVSVKVLD- 20867
Query: 1622 VPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF-- 1679
P A + V H + T + + W+PP +D G I + ++ + T+R ++
Sbjct: 20868 TPAACQKLQVKHVSRGT-VTLLWDPPLIDG------GSPIINYVIEKRDATKRTWSVVSH 20920
Query: 1680 -LAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ S KL +L+ T + V A N G G T+ P+ + + T T
Sbjct: 20921 KCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKT 20980
Query: 1739 SVNVSWEAPQFPNGILEGYRLVY-----EPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAE 1793
SV +SW P F G + +V E G+SK ++ V L E
Sbjct: 20981 SVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIE----------VSQLKE 21030
Query: 1794 GVTYRFRIRAKT-------FTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
FR+ AK T GP + P PG + VR
Sbjct: 21031 QSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR 21079
Score = 164 bits (414), Expect = 1e-39
Identities = 332/1511 (21%), Positives = 556/1511 (36%), Gaps = 169/1511 (11%)
Query: 473 YTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRY--- 529
+ A N +G+ + + + I P D S I G Q ++ G H+ + + Y
Sbjct: 21036 FRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIG--HNVHLELPYKGK 21093
Query: 530 -----IWEKDGATLGTESHPRIRLDRNG-SLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
W KDG L R N +L I G YT + +A +
Sbjct: 21094 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPIT 21153
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAP-WTVLLA 641
+ P P+ P+ ++ ++ L+W P D G + Y +E E + W ++ +
Sbjct: 21154 VITLGPPSKPKGPIR-FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21212
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
SV T+ V LV YQFR+ A N G Q + V+ + PP +
Sbjct: 21213 SV--ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYN 21270
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T+ + + W P + + ++ + + +Q N + L+
Sbjct: 21271 VTSDGMSLTWDAPVYDGGSEVTGFHVEKK--ERNSILWQKVNTSPISGREYRATGLVEGL 21328
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
+Y+ V A NSAGL S +++TL P PPG TI WN P
Sbjct: 21329 DYQFRVYAENSAGLSSPSDP-SKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLR---- 21383
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF-VSGLKKFTEYFTSVLCFTTPG-- 878
+ G K++ + E+ + R NF D + V+GL Y ++ G
Sbjct: 21384 --DGGSKIVGYSIEKRQGNER-WVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI 21440
Query: 879 DGPRSTPQLVRTHEDVPGPV---GHLSFSEIL---DTSLKVSWQEPGEKNGILTGYRISW 932
P + ++ T ++ P+ G F ++ SL++ G +T ++
Sbjct: 21441 SPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGV 21500
Query: 933 EEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
E R N +T L + +L R YT+E A + G + P ++
Sbjct: 21501 EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE--AKNASGSAKAEIKVKVQDTPGKV 21558
Query: 993 PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
GP + +NI +TL + P DG I+ +++E + W LI ++
Sbjct: 21559 VGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRET---SRLAWALIE---DKC 21609
Query: 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1111
+A+S L Y FR+ VN G P + +Q AP +
Sbjct: 21610 EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGN 21669
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLEEWT 1169
S+ L W E +G E Y ++ R + V+ R E + + L E
Sbjct: 21670 SITLTWA---RPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRFKVTGLTEGN 21724
Query: 1170 EYRVQVQAFNAIGSGPWSQ-TVVGRTRESV-PSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
EY V A NA G GP S + + + RE V P PT V T+ +++ + WS+ P D
Sbjct: 21725 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK-PVFD 21783
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
++GY + + D + E +T L Y+ +V A G G
Sbjct: 21784 GGMEIIGYIIEMCKADLGDWHKV-NAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDS 21842
Query: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQ-------ITHRL 1340
+ +D + P + I +T VR A + +AYQ + +
Sbjct: 21843 CEVTGTIKAVDRLTAPELDIDANFKQTHVVRA-----GASIRLFIAYQGRPTPTAVWSKP 21897
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP 1400
++ + A + S T + +T + G ++++ T + D P
Sbjct: 21898 DSNLSLRADIHT-TDSFSTLTVENCNRNDAGKYTLTVENNSG----SKSITFTVKVLDTP 21952
Query: 1401 QPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
PP + +DV S L W+ P DG + + +Y ++ RE W + S +
Sbjct: 21953 GPPGP--ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI- 22009
Query: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT-TLQAAPDEAPTILSVTPHTTTSV 1518
F V+ L Y FRV A N+ G E E E + T Q AP P L V + +S
Sbjct: 22010 -FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP---PRRLDVVDTSKSSA 22065
Query: 1519 LIRWQPPAED---KINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
++ W P D +I G LL R + + E G T +LT
Sbjct: 22066 VLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHT-----------KQLT------- 22105
Query: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV------PTA---- 1625
+ ++ L + YE R+ N G S P+E F + PTA
Sbjct: 22106 --------FTVERLVEKTEYEFRVKAKNDAGY---SEPREAFSSVIIKEPQIEPTADLTG 22154
Query: 1626 -APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTE-RVKTLFLAEN 1683
+ + + +DV P ++ ++ E R ++T + +T ++
Sbjct: 22155 ITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK--ETDRVSITTTKDRTTLTVKD 22212
Query: 1684 SVK---------LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSE 1734
S++ L+N G + V+V G P G + ++ SA S V
Sbjct: 22213 SMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG------PVTGPIEVSSVSAESCV---- 22262
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+SW P+ G E + E ++V VK +KV L +
Sbjct: 22263 -------LSWGEPKDGGGT-EITNYIVEKRESGTTAWQLVNSSVKRTQ---IKVTHLTKY 22311
Query: 1795 VTYRFRIRAKT-FTYGPEIE-ANVTTGPGEGAPGPPGVPIIVRYSS-AIAIHWSSG-DPG 1850
+ Y FR+ ++ F +E A + P P P + S+ A++I W G
Sbjct: 22312 MEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDG 22371
Query: 1851 KGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGT 1910
I Y +E + + LW +K+ + + L G+ Y FR A+N G
Sbjct: 22372 GSKIIGYWVEKKERNTILW---VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 22428
Query: 1911 PSSPSQSVPAQ 1921
S S+ + AQ
Sbjct: 22429 ASEASRPIMAQ 22439
Score = 161 bits (408), Expect = 6e-39
Identities = 283/1169 (24%), Positives = 437/1169 (37%), Gaps = 141/1169 (12%)
Query: 412 TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLI-SPTHISDA 470
T+ G S+ L SG P P ITW K LAS ++ ES SLLI + DA
Sbjct: 22960 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI----IDTTESYSLLIVDKVNRYDA 23015
Query: 471 GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV----- 525
G YT A N G A+ + V+ T P +K V P +
Sbjct: 23016 GKYTIEAENQSGKKSATVLVKVYD----TPGPCPSVKVKEVSRDSVTITWEIPTIDGGAP 23071
Query: 526 TIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVI-----SAGGNDSR 580
YI EK A + + + IS G + Y RV+ G
Sbjct: 23072 VNNYIVEKREAAMRAFKTVTTKCSKT-LYRISGLVEGTM--YYFRVLPENIYGIGEPCET 23128
Query: 581 SAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP-FDGNSPLIRYILEMSENNAPWT 637
S + V ++P P A L V+ + + L W KP +DG S L Y+LE +
Sbjct: 23129 SDAVLVSEVPLVP----AKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERW 23184
Query: 638 VLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS------LPEEPPT 691
+ + ++ P TV L Y FR+ A N+ G + + V+ LP +
Sbjct: 23185 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23244
Query: 692 APPQNVI--ASGRTNQSIM-IQWQPPPESHQNGILKGYIIRYCLAG--LPVGYQFKNITD 746
PQ I +GR + ++ I +PPP + + AG L + T
Sbjct: 23245 TMPQKTIHVPAGRPVELVIPIAGRPPPAAS-----------WFFAGSKLRESERVTVETH 23293
Query: 747 ADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
V L + + I E + N G + KV G PT P + + ++T
Sbjct: 23294 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGP---IKIDEIDAT 23350
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEE-------VTMVTARPNFQDSIHVGFVS 859
+I +W P ++ G L + EQ + V+ R F+ +
Sbjct: 23351 SITISWEPPE------LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFK-------FT 23397
Query: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLV--RTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
L + EY V G G +++ R+ +PGP L ++ + ++W
Sbjct: 23398 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23457
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P + G +TGY + +E + +P YR TGLT Y V A+ ++G
Sbjct: 23458 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23517
Query: 977 GQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVG 1033
G+ S + I + P PG P N +++ SV+L + P +G + ++ +L+E Q
Sbjct: 23518 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23577
Query: 1034 VVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP--SRKIQT 1091
+ EW + + R + L Y FR+ N G P++ + K+
Sbjct: 23578 ---DQHEWTKCNTTPTK--IREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 23632
Query: 1092 LQAPPDMA-----PANVSLRTASETSLWL--RWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
+ PD + +R L + + P P ++ + + + + S+ H
Sbjct: 23633 MLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH 23692
Query: 1145 GKTLSHVVQDRVERDYTIEDL--EEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSS- 1201
+ V+++ D DL E + IGS P+S
Sbjct: 23693 TEL---VIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS---------------PNSP 23734
Query: 1202 -GPTNVSALATTSSSMLVRWSEVPEADRNGL-VLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
GP + S VR S P AD G +LGY + +E W + R
Sbjct: 23735 EGPLEYDDIQVRS----VRVSWRPPADDGGADILGYILERREVPKAA----WYTIDSRVR 23786
Query: 1260 SAQLT--GLGKYVLYEVQVLAFTRIGDGSP--SHPPILERTLDDVPGPPMGILFPEV--- 1312
L GL + V Y +V A + G P S P+ +T + P PP PEV
Sbjct: 23787 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNP--PEVLDV 23844
Query: 1313 RTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
+SV L W P G + R T+T + YT TGL P++ Y
Sbjct: 23845 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 23904
Query: 1373 FRITAQTRKGWGEAAEAL--VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGL 1429
FRI AQ G E + A VV + D+P P ++ + SV L WE P DG
Sbjct: 23905 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE--LEILSISKDSVTLQWEKPECDGG 23962
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+ Y ++ R+ W S F + L T Y+FRV A N+ G S
Sbjct: 23963 KEILGYWVEYRQSGDSAWK-KSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24021
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSV 1518
+ S+ T + EAP I TT +
Sbjct: 24022 TAMSIKT-KLTSGEAPGIRKEMKDVTTKL 24049
Score = 158 bits (400), Expect = 5e-38
Identities = 355/1546 (22%), Positives = 567/1546 (36%), Gaps = 189/1546 (12%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARNAAGEVQTS 392
G P P+I WYKD ++ L D + I ++G ++ RNA G +
Sbjct: 20401 GKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT 20460
Query: 393 TYLAVTSIAPNITRGPLDSTVIDGMSVVL----ACETSGAPRPAITWQKGERILASGSVQ 448
+ + P GP++ + + L + GA +K E S+
Sbjct: 20461 IRVQILD-KPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMV 20519
Query: 449 LPRFTPLESGSLLISPTHISDAGTY--TCLATNSRGVDE-ASADLVVWARTRITK-PPQD 504
+I+ T I Y A N G+ E +D VV +T PP
Sbjct: 20520 SEHLE-----ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI 20574
Query: 505 QSVIKGTQASMVCGVTH-----DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
V K T+ SM + ++ ++ ++D +LG + + T
Sbjct: 20575 PEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLT 20634
Query: 560 WSGDIGTYTCRVISAG-GNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
+ D C V +AG G S + P P P A + + + +I L W+KP
Sbjct: 20635 ENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPV 20694
Query: 616 FDGNSPLIRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S + Y++E+ + WT + + + T V L P +Y FR+ AVN G+G
Sbjct: 20695 YDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG 20754
Query: 675 QFSKDTERVSLPE--EPP-----TAPPQNVIASGRTNQSIMIQW--QPPPESHQNGILKG 725
+ + E V + E P A +VIA + ++I + +PPP K
Sbjct: 20755 EPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKN 20814
Query: 726 YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW 785
G Y +N D ++LL + + + + G+G S
Sbjct: 20815 -------LGSDARYSIEN---TDSSSLLTIPQVTRNDTGKYILTIEN-GVGEPKSSTVSV 20863
Query: 786 TLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTA 845
+ P + + + T+ W+ P I+ G +I + E+ + +
Sbjct: 20864 KVLDTPAACQ-KLQVKHVSRGTVTLLWDPPL------IDGGSPIINYVIEKRDATKRTWS 20916
Query: 846 RPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFS 904
+ + S + L + T +F VL G G P T + V+ E VP P+ LS
Sbjct: 20917 VVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE-VPAPIRDLSMK 20975
Query: 905 EILDTSLKVSWQEPGEKNG-ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTT 963
+ TS+ +SW +P G ++T Y + E + +H + T E V+ L +
Sbjct: 20976 DSTKTSVILSWTKPDFDGGSVITEYVV--ERKGKGEQTWSHAGISKTCEIEVSQLKEQSV 21033
Query: 964 YTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPG------Y 1017
V A KG TI EL P + +S+I VT++ Y
Sbjct: 21034 LEFRVFAKNEKGLS--DPVTIGPITVKELIITP-EVDLSDIPGAQVTVRIGHNVHLELPY 21090
Query: 1018 DGKTSIS-RW------LVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
GK S W L E++ + E + + + + + L+ C
Sbjct: 21091 KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRI-- 21148
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPE 1130
+ ++ PPS+P I+ + D S+ L W +P E NG E
Sbjct: 21149 AVPITVITLGPPSKPKGPIRFDEIKAD--------------SVILSW-DVP--EDNGGGE 21191
Query: 1131 SVGYKI-KYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-S 1187
Y I K S + K + V + + +L + EY+ +V+A N G S P S
Sbjct: 21192 ITCYSIEKRETSQTNWKMVCSSV---ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21248
Query: 1188 QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS--- 1244
+V + + +P P TS M + W + P D V G+ V KE++S
Sbjct: 21249 SIIVAKHQFRIPGP-PGKPVIYNVTSDGMSLTW-DAPVYDGGSEVTGFHVEKKERNSILW 21306
Query: 1245 ---DTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD--D 1299
+T P S R + TGL + + Y+ +V A G SPS P + D
Sbjct: 21307 QKVNTSP-------ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVD 21359
Query: 1300 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSA 1357
PG P I +V ++ L W PP G I+ Y I R N +V S
Sbjct: 21360 PPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDV---SE 21413
Query: 1358 RQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARS 1417
QYT TGL P Y FRI A+ G RD P P+V+
Sbjct: 21414 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVP---PIVEFGPEYFDG 21470
Query: 1418 VLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY----- 1472
+++ G S +Q R +P W + + I D L + +
Sbjct: 21471 LII-----KSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT 21525
Query: 1473 -----KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAE 1527
+ V+A N G S ++E +Q P + + T T + + W P
Sbjct: 21526 RDHRGVYTVEAKNASG----SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLN 21581
Query: 1528 DKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELD 1587
D I + I RE WA + S T +L
Sbjct: 21582 DGCAPI-THYIIEKRE---------------TSRLAWALIED-----KCEAQSYTAIKLI 21620
Query: 1588 NLNKHRRYEIRMSVYNAVGEGP--SSPPQEVFVGEAVPTA----APRNVVVHGATATQLD 1641
N N+ Y+ R+S N G G S P + VP A P N+ T +
Sbjct: 21621 NGNE---YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNI-----TGNSIT 21672
Query: 1642 VTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVA 1701
+TW P D +IQ Y + E + + + ++E K+ LT Y V
Sbjct: 21673 LTWARPESDG-GSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVM 21731
Query: 1702 AFNAAGDGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGY 1757
A NAAG GP S + + + P P+ VK ++ + T+V++ W P F G+ + GY
Sbjct: 21732 AENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGY 21791
Query: 1758 RLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA 1803
+ E C + V+ + V DL G Y+FR+ A
Sbjct: 21792 --IIEMCKA--DLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSA 21833
Score = 158 bits (399), Expect = 6e-38
Identities = 319/1434 (22%), Positives = 534/1434 (37%), Gaps = 160/1434 (11%)
Query: 531 WEKDGATLGTESHPRIRLD-RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL 589
W KD A + + I+ +L + D G Y V ++ G+ + V
Sbjct: 10355 WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10414
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P PV+ V + + ++W P D G S + YI+E E + + S K T
Sbjct: 10415 PGPPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-T 10472
Query: 649 SVTVKGLVPARSYQFRLCAVNDVG-KGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
+ V L+ + Y FR+ A N G D+ + P AP Q ++ T S
Sbjct: 10473 TCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEV-TKDSA 10531
Query: 708 MIQWQPPPESHQNGI-LKGYIIRYCLAGLPVGYQFKNITDADVN---NLLLEDLIIWTNY 763
++ W P H G + YI+ + ++ +T ++ + DL+ Y
Sbjct: 10532 LVTWNKP---HDGGKPITNYILE---KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 10585
Query: 764 EIEVAAYNSAGLGVYS--SKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
E V+A N G+G S SK PP N A T ++ TW P +
Sbjct: 10586 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10645
Query: 822 GINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG- 880
I GY ++ ++ +EE P V+GL+ Y VL G+
Sbjct: 10646 KI-LGY-IVEYQKVGDEEWRRANHTPESCPETKYK-VTGLRDGQTYKFRVLAVNAAGESD 10702
Query: 881 PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGY---RISWEEYNR 937
P P+ V + + P L + + +KV + + I+ G +++W++ +R
Sbjct: 10703 PAHVPEPVLVKDRLEPPELILDANMAREQHIKVG--DTLRLSAIIKGVPFPKVTWKKEDR 10760
Query: 938 ---TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGV-PPELP 993
T R+ LE R Y++ V + + T+S V + P
Sbjct: 10761 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLVLDKP 10813
Query: 994 GPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
GPP +L +S I S L ++ P DG + I+ ++VE + +W LS
Sbjct: 10814 GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVA---SAQW---SPLSATSK 10867
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ-APPDMAPANVSLRTASET 1111
+S LN Y FR+ N G P + + I+ L P P ++ +T
Sbjct: 10868 KKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKT 10927
Query: 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG----KTLSHVVQDRVERDYTIEDLEE 1167
+ L W + + +G GY ++Y KT++++ + + L++
Sbjct: 10928 EVSLVW---NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNL-------ECVVTGLQQ 10977
Query: 1168 WTEYRVQVQAFNAIGSGPWSQTVVGRTRES-VPSSGPTNVSAL--------ATTSSSMLV 1218
YR +V+A N +G G T+ +E VP S +V + T ++
Sbjct: 10978 GKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAII 11037
Query: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
R VP A K + T + + N S + + E Q+
Sbjct: 11038 RGVPVPTA---------KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI-- 11086
Query: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMG-ILFPEVRTTSVRLIWQPPAAPNGIILAYQIT 1337
+ + + S + T+ DVPGPP G I +V + + WQPP G + I
Sbjct: 11087 --TVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIV 11144
Query: 1338 HRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEK 1396
+ T +T V S + L+ Y+FR+ A+ + G G ++ V K
Sbjct: 11145 EK-QDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHK 11203
Query: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVS 1455
P PP +P+V D+ + +SW P SDG SP+ Y ++ RE+ +G+W + +
Sbjct: 11204 FSPPSPPGKPVV--TDITENAATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPI 11260
Query: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHT 1514
+ F V L +Y+FRV A N G S+ S S+ + + P I + +
Sbjct: 11261 ADL-KFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKS 11319
Query: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMR 1574
+ + W P D + IL G+ + A W + +R
Sbjct: 11320 RETADLVWTKPLSDGGSPIL----------------GYVVECQKPGTAQWNRINKDELIR 11363
Query: 1575 NLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVVV 1632
+ + + L + Y R+ N VGEG E + + + P +V
Sbjct: 11364 QCA------FRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTC 11417
Query: 1633 HGATATQLDVTW----------EPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
++ T EP ++ G + R + ++ L E
Sbjct: 11418 RDVITVRVGQTIRILARVKGRPEPDITWTKEGKV---------LVREKRVDLIQDLPRVE 11468
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
+K + Y++S A N++G S + P ++K + +T + +
Sbjct: 11469 LQIKEAVRADHGKYIIS--AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKENCTI 11523
Query: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIR 1802
SWE P NG E + E P IV DV + +K LA Y FR+
Sbjct: 11524 SWENP-LDNGGSEITNFIVEYRKPNQKGWSIVASDV---TKRLIKANLLANN-EYYFRVC 11578
Query: 1803 AKT-FTYGPEIEA-------NVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGD-PGKGP 1853
A+ GP IE N PGE P + I + + + + W D G P
Sbjct: 11579 AENKVGVGPTIETKTPILAINPIDRPGE----PENLHIADKGKTFVYLKWRRPDYDGGSP 11634
Query: 1854 ITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYG 1907
Y +E R W+ + K KE + +D Y+FRV N+ G
Sbjct: 11635 NLSYHVERRLKGSDDWERVHKGSIKETH---YMVDRCVENQIYEFRVQTKNEGG 11685
Score = 158 bits (399), Expect = 6e-38
Identities = 293/1278 (22%), Positives = 490/1278 (38%), Gaps = 155/1278 (12%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW-YKDAAVVEVEKLTRFRQR 360
L VL P++ I + V++ G PPP+ +W + + + E E++T
Sbjct: 23235 LRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 23294
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
L I DTG + +N G + T + P GP+ ID S+
Sbjct: 23295 KVAKLTIRETTIRDTGEYTLELKNVTG-TTSETIKVIILDKPGPPTGPIKIDEIDATSIT 23353
Query: 421 LACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISP---THISDAGTY 473
++ E GAP ++ P + P+ S S+ S T +++ Y
Sbjct: 23354 ISWEPPELDGGAPLSGY-------VVEQRDAHRPGWLPV-SESVTRSTFKFTRLTEGNEY 23405
Query: 474 T--CLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW 531
ATN G+ V+ R+ I P +++ + V+ D Y
Sbjct: 23406 VFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETL-------QIFDVSRDGMTLTWYPP 23458
Query: 532 EKDGATLGT---ESHPRIRLD---RNGSLHISQTWSGDIG-----TYTCRVIS----AGG 576
E DG + T +R D R + ++ T G Y RV + G
Sbjct: 23459 EDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 23518
Query: 577 NDSRSAHLRVRQLPHA----PEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSE 631
SR + V P A P++P T +T R +++L W+ P D G S + Y++EM +
Sbjct: 23519 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTT--RTSVSLAWSVPEDEGGSKVTGYLIEMQK 23576
Query: 632 NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFS------KDTERVSL 685
+ + K T+ L Y+FR+ A N G G+ + K TE +
Sbjct: 23577 VDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEY 23636
Query: 686 PEEPPTAPPQN---VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
P+ Q V G +I I+ +P P I ++ G + +
Sbjct: 23637 PDYELDERYQEGIFVRQGGVIRLTIPIKGKPFP-----------ICKWTKEGQDISKRAM 23685
Query: 743 NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEA 802
T L++++ + ++ N G KV + G P P G + +
Sbjct: 23686 IATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKV---RVIGSPNSPEGPLEYDD 23742
Query: 803 TNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSG 860
++R +W P+ + G ++ + E+ E + T + + V V G
Sbjct: 23743 IQVRSVRVSWRPPAD------DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKG 23794
Query: 861 LKKFTEYFTSVLCFTTPG-DGPRSTPQLVRTHEDVPGPVGHLSFSEILD---TSLKVSWQ 916
LK+ EY V G P + + V + P + E+LD +S+ +SW
Sbjct: 23795 LKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 23854
Query: 917 EPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSK 974
P + G +TGY I +E T+ V H +T Y VTGL Y + A
Sbjct: 23855 RPKDDGGSRVTGYYIERKE-TSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDV 23913
Query: 975 GQGQVSAST--ISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYD-GKTSISRWLVEA 1030
G + S ++ + P + P P L I +I SVTLQ+ +P D GK + W+
Sbjct: 23914 GLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYR 23973
Query: 1031 QVGVVGEGEEWLLIHQLSNEPDARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
Q G W + SN+ + + + L T Y FR+ N G S P + +
Sbjct: 23974 QSG----DSAW----KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 24025
Query: 1089 IQTL----QAP---PDMAPANVSLRTASETSLWLRWMPLPEME-YNGNPESVGYKIKYSR 1140
I+T +AP +M L A++ S + PLP+++ Y E + +
Sbjct: 24026 IKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 24085
Query: 1141 SDGHGKTLSHVVQDRVERDY-----TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRT 1194
SDG TL+ + +++ + T E E T ++ +QA G P + G
Sbjct: 24086 SDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG-- 24143
Query: 1195 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKD---SDTQPRFW 1251
+V S+ +V + +M W G K++ ++ +T+
Sbjct: 24144 --AVGSTLRLHVMYIGRPVPAM--TWFH-----------GQKLLQNSENITIENTEHYTH 24188
Query: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMG-ILFP 1310
LV N R T GKY + V + IL+ + D P P G I+
Sbjct: 24189 LVMKNVQRK---THAGKYKVQLSNVFG---------TVDAILDVEIQDKPDKPTGPIVIE 24236
Query: 1311 EVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
+ S + W+PPA G + + + + A S L +
Sbjct: 24237 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 24296
Query: 1371 YLFRITAQTRKGWGEAAE--ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSD 1427
Y FR++AQ G + E ++V+ ++P P +P + V S +++W+ P SD
Sbjct: 24297 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA--VTKDSCVVAWKPPASD 24354
Query: 1428 GLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEF 1487
G + +R Y ++ RE +W + + + F V L Y+FRVK N G+SE+
Sbjct: 24355 GGAKIRNYYLEKREKKQNKW-ISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24413
Query: 1488 SEESESLTTLQAAPDEAP 1505
SE SE +T P +AP
Sbjct: 24414 SEISEPITPKSDVPIQAP 24431
Score = 154 bits (390), Expect = 7e-37
Identities = 325/1603 (20%), Positives = 591/1603 (36%), Gaps = 176/1603 (10%)
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV-EVEKLTRFRQRNDGGLQISGLVPDDT 375
++ A + +D+P KG P ++ W KD + E ++ + L I +D
Sbjct: 18908 NVKAREQLKIDVPF--KGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDV 18965
Query: 376 GMFQCFARNAAGEVQTS-TYLAVTSIAPNITRGPLDSTVIDGMSVVLA---------CET 425
G ++ N+AG + T + + P GP+ + S+ ++ C+
Sbjct: 18966 GTYELCVSNSAGSITVPITIIVLDRPGPP---GPIRIDEVSCDSITISWNPPEYDGGCQI 19022
Query: 426 SG-----APRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
S + TW + +A S+++ R T +GS + A N
Sbjct: 19023 SNYIVEKKETTSTTWHIVSQAVARTSIKIVRLT---TGSEY----------QFRVCAENR 19069
Query: 481 RGVDEASADLVVWARTRITKP--PQDQSVIKGTQASM--------------VCGVTHDPR 524
G S V A + P P V+ T+++M V G + +
Sbjct: 19070 YGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYK 19129
Query: 525 VTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH- 583
+W K L ++ ++ G ++ + ++ +I G S+S
Sbjct: 19130 ERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGI--------GKCSKSCEP 19181
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLAS 642
+ R P P T + R++++L W+KP +DG + + YI+E E +
Sbjct: 19182 VPARDPCDPPGQPEVT--NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 19239
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGK-GQFSKDTERVSLPEEPPTAPPQNVIASG 701
+ + T V L + Y+FR+ A N + S+ T + + ++ P V+
Sbjct: 19240 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDD---VEPPRVMMDV 19296
Query: 702 RTNQSIMIQWQPPPESHQNGILKGY---IIRYCLAGLPVGYQFKN-ITDADVNNLL-LED 756
+ I+++ + N + G +I + G+ + + + I D + LL ++D
Sbjct: 19297 KFRDVIVVKAGEVLKI--NADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 19354
Query: 757 LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
I + + N AG S + P P G + + +W P
Sbjct: 19355 CIRRDTGQYVLTLKNVAGT---RSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 19411
Query: 817 PQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTT 876
G + Y ++ E + + Q + V+ L K EY V
Sbjct: 19412 ED--GGADIDYYIV--EKRETSHLAWTICEGELQMTSCK--VTKLLKGNEYIFRVTGVNK 19465
Query: 877 PGDGPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWE 933
G G ++ + VP P L + + S+ + W P G ++GY I
Sbjct: 19466 YGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERR 19525
Query: 934 EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST--ISSGVPPE 991
E N + P L + TGL Y V A + G S ++ I + P
Sbjct: 19526 EKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVF 19585
Query: 992 LPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 1050
LP PP+ I + G ++T+ + +P +DG I+ + VE + + +W Q
Sbjct: 19586 LPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKS---DDTDWKTSIQSLRG 19642
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPS-------RKIQTL-QAPPDMAPAN 1102
+ + L Y FR++ VN VG S PS S R+ + L +M
Sbjct: 19643 TE---YTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTL 19699
Query: 1103 VSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTI 1162
+ AS T M +P + G P + +S+ D +T ++V TI
Sbjct: 19700 IVKAGASFT------MTVP---FRGRPVP---NVLWSKPDTDLRTRAYVDTTDSRTSLTI 19747
Query: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222
E+ + + N + + S T+V + ++ PTN++ T S ++ W +
Sbjct: 19748 ENANRNDSGKYTLTIQNVLSAA--SLTLVVKVLDT--PGPPTNITVQDVTKESAVLSW-D 19802
Query: 1223 VPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR-SAQLTGLGKYVLYEVQVLAFTR 1281
VPE D V Y + EK ++ + V N +R S ++T L + +Y +V
Sbjct: 19803 VPENDGGAPVKNYHI---EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENE 19859
Query: 1282 IGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLN 1341
G G P+ + + + P PP + + SV L W P G + + + L
Sbjct: 19860 FGVGIPAETKEGVK-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALE 19918
Query: 1342 TTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQ 1401
N V+ + + +GL+ S Y FR+ A+ + G + E L+ K ++ +
Sbjct: 19919 KGQKNW--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIK-EQLE 19975
Query: 1402 PPSRPMVQQED----VRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
PP M VRA S L P S P+ T+ +P + ++
Sbjct: 19976 PPEIDMKNFPSHTVYVRAGSNLKVDIPISG--KPLPKVTLSRDGVPLKATMRFNTEITAE 20033
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
+ + + ++ + A N G ++ L + P P ++S T S
Sbjct: 20034 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLD--RPGPPTGPVVISDI--TEES 20089
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLS 1577
V ++W+PP D + + + L A W E+++ + +
Sbjct: 20090 VTLKWEPPKYDGGSQVT----------------NYILLKRETSTAVWTEVSATVARTMMK 20133
Query: 1578 RPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVV-VHGAT 1636
LT E Y+ R+ N G V V T P + V T
Sbjct: 20134 VMKLTTGE--------EYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVT 20185
Query: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAY 1696
+ V W P + + + GY + + + L ++ L + K+ ++ Y
Sbjct: 20186 RESITVGWHEP-VSNGGSAVVGYHLEMKD-RNSILWQKANKLVIRTTHFKVTTISAGLIY 20243
Query: 1697 MVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LE 1755
V A NAAG G S P++ A P +V+ ++++ SV++SW+ P F G +
Sbjct: 20244 EFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKIT 20303
Query: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPE 1811
GY + E DG + + + L + Y FR+ A+ + + E
Sbjct: 20304 GY--IVERRDLPDG--RWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20359
Query: 1812 IEANVTTGPGEGAPG---PPGVPIIVRYSSAIAIHWSSGDPGK 1851
+ +T G P P +V+Y + ++ +G GK
Sbjct: 20360 VVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 20402
Score = 149 bits (376), Expect = 3e-35
Identities = 359/1701 (21%), Positives = 599/1701 (35%), Gaps = 236/1701 (13%)
Query: 305 LEPPQFVKEPERH--ITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTR---FRQ 359
+EPP+ + + + I + +V+ I G P P I+W KD +E+E+ R
Sbjct: 19287 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDG--IEIEERARTEIIST 19344
Query: 360 RNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSV 419
N L + + DTG + +N AG + V P GPL+ +
Sbjct: 19345 DNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLD-KPGPPAGPLEINGLTAEKC 19403
Query: 420 VLAC----ETSGAPRPAITWQKGER-----ILASGSVQLP--RFTPLESGSLLISPTHIS 468
L+ E GA +K E + G +Q+ + T L G+ I
Sbjct: 19404 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI------ 19457
Query: 469 DAGTYTCLATNSRGVDEASADLVVWARTRIT--KPPQDQSVIKGTQASMVCGVTHDPRVT 526
+ N GV E + + A T PP + T+ SM
Sbjct: 19458 ----FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMT---------- 19503
Query: 527 IRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W + + G+E I ++R + Y RV S G + RV
Sbjct: 19504 --LCWSRPESDGGSEISGYI-IERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRV 19560
Query: 587 RQ-----------------------LPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPL 622
LP P P S + I + W KP FDG +P+
Sbjct: 19561 YAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDS--GKTTITIAWVKPLFDGGAPI 19618
Query: 623 IRYILEMSE-NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTE 681
Y +E + ++ W + S+ + T T+ GL Y FR+ +VN VG S ++
Sbjct: 19619 TGYTVEYKKSDDTDWKTSIQSL--RGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19676
Query: 682 RVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILK---GYIIRYCLAGLPVG 738
PQ IA R + + + E + I+K + + G PV
Sbjct: 19677 ------------PQ--IAKEREEEPL---FDIDSEMRKTLIVKAGASFTMTVPFRGRPVP 19719
Query: 739 YQFKNITDADVNNLLLEDLI-IWTNYEIEVAAYNSAG------LGVYSSKVTEWTLQGVP 791
+ D D+ D T+ IE A N +G V S+ ++ +
Sbjct: 19720 NVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLD 19779
Query: 792 TV-PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 850
T PP N+ + + +W+ P N K E + + V+ N
Sbjct: 19780 TPGPPTNITVQDVTKESAVLSWDVPE----NDGGAPVKNYHIEKREASKKAWVSVTNNCN 19835
Query: 851 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDG-PRSTPQLVRTHEDVPGPVGHLSFSEILDT 909
+ V+ L++ Y+ V G G P T + V+ E P P L + I
Sbjct: 19836 RLSYK--VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK-PSPPEKLGVTSISKD 19892
Query: 910 SLKVSWQEPGEKNGI-LTGYRISWEEYNRTN------TRVTHYLPNVTLEYRVTGLTALT 962
S+ ++W +P G + Y + E + N + TH++ V+GL +
Sbjct: 19893 SVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHV--------VSGLRENS 19944
Query: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
Y V A G + + +L P + + N S T+ R G + K
Sbjct: 19945 EYFFRVFAENQAGLSDPRELLLPVLIKEQL--EPPEIDMKNF--PSHTVYVRAGSNLKVD 20000
Query: 1023 IS-RWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSP 1081
I +V + +G + + E A ++ + T + R ++ +S
Sbjct: 20001 IPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY-EITAANSSG 20059
Query: 1082 PSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY-KIKYS 1139
++ I L P P P +S +E S+ L+W P +Y+G + Y +K
Sbjct: 20060 TTKAFINIVVLDRPGPPTGPVVIS--DITEESVTLKWEP---PKYDGGSQVTNYILLKRE 20114
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
S +S V + + + L EY+ +++A N G + +
Sbjct: 20115 TSTAVWTEVSATVARTMMK---VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYT 20171
Query: 1200 SSGPTNVSALA-TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN-- 1256
+ GP + + T S+ V W E P ++ V+GY + K+++S W
Sbjct: 20172 TPGPPSTPWVTNVTRESITVGWHE-PVSNGGSAVVGYHLEMKDRNS----ILWQKANKLV 20226
Query: 1257 -SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVR 1313
+ ++T + ++YE +V A G G PSHP P+L D PP + ++
Sbjct: 20227 IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVL---AIDACEPPRNVRITDIS 20283
Query: 1314 TTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
SV L WQ PA G + I R + + Q+ +GL S Y F
Sbjct: 20284 KNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEF 20343
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPP--SRPMVQQEDVRARS-VLLSWEPGSDGL- 1429
R+ A+ G +V D P P+ E V+ R+ + G G
Sbjct: 20344 RVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKP 20403
Query: 1430 SPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
+P + +EL + AL + + +S ++ S + +K N +G + +
Sbjct: 20404 APTIEWYKDDKELQTN--ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 20461
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGL 1549
+ L + P P + T + + W+PPA+D G +I +
Sbjct: 20462 RVQILD--KPGPPGGP--IEFKTVTAEKITLLWRPPADDG------GAKITH-------- 20503
Query: 1550 RGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP 1609
+ + W+ ++ +L +T + K Y R+ N G G
Sbjct: 20504 --YIVEKRETSRVVWSMVS-----EHLEECIIT---TTKIIKGNEYIFRVRAVNKYGIGE 20553
Query: 1610 SSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR 1668
V A T P + V T + V W P D DI G YF E +
Sbjct: 20554 PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADG-GSDISG---YFLEKRD 20609
Query: 1669 GNLTERVKTL--FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ---GQTQQAA 1723
K L + + K+ LT + Y V A NAAG GP S P++
Sbjct: 20610 KKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 20669
Query: 1724 PSAPSSVKFSELTTTSVNVSWEAPQFPNG-ILEGYRLVYEPCSPVDGVSKIVTVDVKGN- 1781
P P+ ++ ++ T +S+ + W P + G + GY + + TV KG
Sbjct: 20670 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE----EEWTTVSTKGEV 20725
Query: 1782 SPLWLKVKDLAEGVTYRFR------------------IRAKTFTYGPEIEANVTTGPGEG 1823
V +L GV Y FR ++AK PEI+ +V
Sbjct: 20726 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVI 20785
Query: 1824 APGPPGVPIIVRYSS--AIAIHWSSGDPGKGPITRYVIEARPS------------DEGLW 1869
A V +++ + + W + G RY IE S D G +
Sbjct: 20786 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20845
Query: 1870 DILIKDIPKEVSSYTFSMDIL 1890
+ I++ E S T S+ +L
Sbjct: 20846 ILTIENGVGEPKSSTVSVKVL 20866
Score = 149 bits (376), Expect = 3e-35
Identities = 360/1644 (21%), Positives = 594/1644 (36%), Gaps = 223/1644 (13%)
Query: 367 ISGLVPDDTGMFQCFARNAAG-----EVQTSTYLAVTSIAPNITRGPLDSTVID---GMS 418
++ L + +F+ A+N G E T+ + + P I + I G
Sbjct: 23199 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23258
Query: 419 VVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 477
V L +G P PA +W G ++ S V + T + L I T I D G YT
Sbjct: 23259 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV--AKLTIRETTIRDTGEYTLEL 23316
Query: 478 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASM------------VCGVTHDPRV 525
N G + +++ + P I T ++ + G + R
Sbjct: 23317 KNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRD 23376
Query: 526 TIRYIW--EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAH 583
R W + T T R+ ++ T IG+Y + + + RS+
Sbjct: 23377 AHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSI 23432
Query: 584 LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLAS 642
++P PE + V R + LTW P D G S + YI+E E A V +
Sbjct: 23433 ----RIPGPPE--TLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNK 23486
Query: 643 VDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTER-VSLPEEPPTAPPQNVIASG 701
V T GL Y+ R+ A+N G G+ S+ ++ V++ P PQN +
Sbjct: 23487 VPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTD 23546
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
T S+ + W P E + GY+I + N T + L L
Sbjct: 23547 TTRTSVSLAWSVP-EDEGGSKVTGYLIEMQKVDQHEWTKC-NTTPTKIREYTLTHLPQGA 23604
Query: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
Y V A N+ G G P PG V + + + ++
Sbjct: 23605 EYRFRVLACNAGG-------------PGEPAEVPGTVKV----TEMLEYPDYELDERYQE 23647
Query: 822 GI--NQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
GI QG + P + + + QD ++ + TE V+ GD
Sbjct: 23648 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL---VIKEADRGD 23704
Query: 880 ------------GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LT 926
G ++ VR P G L + +I S++VSW+ P + G +
Sbjct: 23705 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23764
Query: 927 GYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV--SASTI 984
GY + E + T V GL Y V+A G + S +
Sbjct: 23765 GYILERREVPKAAWYTIDSRVRGT-SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 23823
Query: 985 SSGVPPELPGPPTNLG-ISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWL 1042
+ P P PP+N + ++ SV+L + RP DG + ++ + +E + ++W
Sbjct: 23824 TPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETST---DKW- 23879
Query: 1043 LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG---TSPPSQPSRKIQTLQAPPDMA 1099
+ + V L P Y FR+ N VG TSP S+P P
Sbjct: 23880 -VRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQ-- 23936
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV-ER 1158
P + + + S+ S+ L+W + E +G E +GY ++Y +S S+ ++R+ ++
Sbjct: 23937 PGELEILSISKDSVTLQW---EKPECDGGKEILGYWVEYRQSGDSAWKKSN--KERIKDK 23991
Query: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP----------TNVSA 1208
+TI L E TEY +V A N G +T + + P T +
Sbjct: 23992 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGE 24051
Query: 1209 LATTSSSMLVRWSEVPEADRNGLVLGYKVMYK-EKDSDTQPRFWLVEGNSSRSAQLTGLG 1267
A S ++ R + R G L YK D T + E G
Sbjct: 24052 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDE-------G 24104
Query: 1268 KYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL----IWQP 1323
Y +A +G+ S +L+ T PG P+ + +++RL I +P
Sbjct: 24105 VYTC-----IATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRP 24159
Query: 1324 PAAPNGIILAYQITHRLNTTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A + + N T NT ++ + ++ T G +++ G
Sbjct: 24160 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK-------YKVQLSNVFG 24212
Query: 1383 WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYTIQTRE 1441
+A ++ E +D+P P+ P+V E + S ++SW+P DG S + Y ++ E
Sbjct: 24213 TVDA----ILDVEIQDKPDKPTGPIVI-EALLKNSAVISWKPPADDGGSWITNYVVEKCE 24267
Query: 1442 LPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
G W L S+++S + L Y FRV A N G S+ E S + +
Sbjct: 24268 AKEGAEWQLVSSAISVTTCRIV--NLTENAGYYFRVSAQNTFGISDPLEVSS--VVIIKS 24323
Query: 1501 PDE---APTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
P E AP ++T T S ++ W+PPA D G +IR + L
Sbjct: 24324 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDG------GAKIR----------NYYLEKR 24367
Query: 1558 NNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617
W +T+ T + + NL + YE R+ N GE S E
Sbjct: 24368 EKKQNKWISVTTEEIRE-------TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPI 24420
Query: 1618 VGEA-VPTAAPR--------NVVVHGATATQLDVTWEPPPL------------DSQNGDI 1656
++ VP AP NV VT P P+ D I
Sbjct: 24421 TPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRI 24480
Query: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ 1716
Q +K + + ++T+ T++ + + +++G + V V A P++
Sbjct: 24481 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL---PKTLEGM 24537
Query: 1717 GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTV 1776
G A S+K ++W+ Q Y+++ V++ T
Sbjct: 24538 GAVH-ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI---------VTRSFTS 24587
Query: 1777 DVKGNSPLWLKVKDLAEGVTY---RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPII 1833
V N ++ KD V RF I KT +E +V P P GV +
Sbjct: 24588 LVFPNG---VERKDAGFYVVCAKNRFGIDQKT------VELDVADVPDP----PRGVKVS 24634
Query: 1834 VRYSSAIAIHWSS-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892
++ + W+ G IT Y++E + W + + +++ L
Sbjct: 24635 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-----GQARETRYTVINLFG 24689
Query: 1893 GVSYDFRVIAVNDYGFGTPSSPSQ 1916
SY FRVIA N +G PS PS+
Sbjct: 24690 KTSYQFRVIAENKFGLSKPSEPSE 24713
Score = 147 bits (372), Expect = 8e-35
Identities = 327/1497 (21%), Positives = 538/1497 (35%), Gaps = 177/1497 (11%)
Query: 361 NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV 420
ND G+ ++PD + R A + + L T + V G+S+
Sbjct: 14255 NDAGVGEPAVIPD----VEIVEREMAPDFELDAELRRTLV------------VRAGLSIR 14298
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT-HISDAGTYTCLATN 479
+ G P P +TW K L + + ES +LLI P + D G + N
Sbjct: 14299 IFVPIKGRPAPEVTWTKDNINLKNRA----NIENTESFTLLIIPECNRYDTGKFVMTIEN 14354
Query: 480 SRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH--------DPRVTIRYIW 531
G + R+ P ++ T + H R+T YI
Sbjct: 14355 PAGKKSG------FVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT-NYIV 14407
Query: 532 EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA-----GGNDSRSAHLRV 586
EK AT + S + + T + Y RV++ G + ++
Sbjct: 14408 EKREATRKSYSTATTKCHK---CTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14464
Query: 587 RQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDP 645
+ P P+ + + + ++L W KP DG S + Y++E + + +V
Sbjct: 14465 SEAPSPPDS--LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV-- 14520
Query: 646 KATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT-----ERVSLPEEPPTAPPQN-VIA 699
K V+ L Y F++ AVN G+ + E+ LPE Q VIA
Sbjct: 14521 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIA 14580
Query: 700 SGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLII 759
N + I P+ I++ V ++ T A L + + +
Sbjct: 14581 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQR---VNFE----TTATSTILNINECVR 14633
Query: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
+ + A N G V + +P P G + + +S + F+W+ P
Sbjct: 14634 SDSGPYPLTARNIVG---EVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPEND- 14689
Query: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
G+ ++ E Q + T V + + + L EY V G
Sbjct: 14690 -GGVPISNYVV--EMRQTDSTTWVELATTVIRTTYKA--TRLTTGLEYQFRVKAQNRYGV 14744
Query: 880 GPRSTPQLVRTHED--VPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYN 936
GP T + + VPGP G + + S+ +SW EP G + GY + +E N
Sbjct: 14745 GPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERN 14804
Query: 937 RTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAA--MTSKGQGQVSASTISSGVPPELPG 994
+ ++ +GLT Y V A M K + + + + P + PG
Sbjct: 14805 GILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPG 14864
Query: 995 PPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDA 1053
P L NI +VTL++ +P Y G I+ ++VE + G + + L NE
Sbjct: 14865 KPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENE--- 14918
Query: 1054 RSMEVPDLNPFTCYSFRMRQVNIVGT-SPPSQPSRKI---QTLQAPP---DMAPANVSLR 1106
V L Y FR+ N G SPPS+PS I ++AP D+ + +
Sbjct: 14919 --FTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 14976
Query: 1107 TASET---SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIE 1163
A E + P P ME++ + + + K ++ + V +D T
Sbjct: 14977 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIK------IADFSTNLVNKDSTRR 15030
Query: 1164 DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEV 1223
D +T + A N G V R P GP V+ + TS ++ W
Sbjct: 15031 DSGAYT-----LTATNPGGFAKHIFNVKVLDRPG-PPEGPLAVTEV--TSEKCVLSW--F 15080
Query: 1224 PEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL--TGLGKYVLYEVQVLAFTR 1281
P D G + + ++ K +T W + + +L T L K Y +V+A +
Sbjct: 15081 PPLDDGGAKIDHYIVQKR---ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNK 15137
Query: 1282 IGDGSP-SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRL 1340
G G P P+L P PP + S+ + W P + G + I R
Sbjct: 15138 YGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR 15197
Query: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG--EAAEALVVTTEKRD 1398
+ + +Y +GL Y FRI A+ G +
Sbjct: 15198 DKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 15257
Query: 1399 RPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHN 1457
+P PP P V D S+ ++W +P DG S + Y ++ W + +
Sbjct: 15258 KPGPPGNPRVL--DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLK 15315
Query: 1458 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1517
A+S+ + L YK R+ A N G E P ++ TP
Sbjct: 15316 ATSYTITGLTENQEYKIRIYAMNSEGLGE------------------PALVPGTPKAEDR 15357
Query: 1518 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFT-LRGINNPGATWAELTSMYSMRNL 1576
+L P E +++ L + R LR F ++G P WA S+
Sbjct: 15358 ML-----PPEIELDADLRKV-VTIRACC--TLRLFVPIKGRPAPEVKWAR-DHGESLDKA 15408
Query: 1577 SRPSLTQYEL---DNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV--PTAAPRNVV 1631
S S + Y L N+N+ + ++V N SS + FV V P+++
Sbjct: 15409 SIESTSSYTLLIVGNVNRFDSGKYILTVEN------SSGSKSAFVNVRVLDTPGPPQDLK 15462
Query: 1632 VHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA---ENSVKLK 1688
V T T + +TW+PP LD G KI + ++ T + + + S K+
Sbjct: 15463 VKEVTKTSVTLTWDPPLLDG------GSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVD 15516
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
L +Y V A N G G + + P P + ++T SV++SWE P+
Sbjct: 15517 QLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPE 15576
Query: 1749 FPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
G + GY +V D + TV V + + L +G Y FR+ A+
Sbjct: 15577 HDGGSRILGY-IVEMQTKGSDKWATCATVKVTEAT-----ITGLIQGEEYSFRVSAQ 15627
Score = 142 bits (357), Expect = 5e-33
Identities = 357/1681 (21%), Positives = 598/1681 (35%), Gaps = 218/1681 (12%)
Query: 289 RSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAV 348
RS +VP V + V+EP VK + ++ + + I G P P+ITW KD
Sbjct: 16718 RSLAVPIVAKDL---VIEPD--VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG-- 16770
Query: 349 VEVEKLTRFRQRND---GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ +++ TR + L I DD G + N G+ +T++ VT P+
Sbjct: 16771 LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-KTASIEIVTLDKPDPP 16829
Query: 406 RGPLDSTVIDGMSVVLACE----TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+GP+ + S+ L+ T G QK + V + +L
Sbjct: 16830 KGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVV---SATVARTTLK 16886
Query: 462 ISPTHISDAGTYTCLATNSRGVDEA--SADLVVWARTRITKPP---------QDQSVIK- 509
++ + A N G A S +V + PP +D VI+
Sbjct: 16887 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 16946
Query: 510 ----GTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIG 565
S V G + + +W K T+ ++ + + ++ + +
Sbjct: 16947 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQ-------NLEEGIEYEFR 16999
Query: 566 TYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIR 624
Y ++ G S R P P + V+R I L WTKP +DG S +
Sbjct: 17000 VYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITG 17057
Query: 625 YILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT---- 680
YI+E + + + + T TV GL + Y+FR+ A N G D+
Sbjct: 17058 YIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 17117
Query: 681 ---ERVSLP--EEPPTAPPQNVIASGRT-NQSIMIQWQPPPESHQNGILKGYIIRYCLAG 734
+ V LP P V+ +G T + +P P +
Sbjct: 17118 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLP---------------TIEW 17162
Query: 735 LPVGYQFKNITDADVNN------LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ 788
L + + ++ N L+++D I + + A N AG + V +
Sbjct: 17163 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV---KVL 17219
Query: 789 GVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN 848
P P G V S TW SP +G + + + E V A
Sbjct: 17220 DRPGPPEGPVQVTGVTSEKCSLTW---SPPLQDGGSDISHYVVEKRETSRLAWTVVASEV 17276
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEI 906
+S+ V+ L + EY ++ G G S P L++ +PGP L + I
Sbjct: 17277 VTNSLK---VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNI 17333
Query: 907 LDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTR-VTHYLPNVT-LEYRVTGLTALTT 963
S+ V W P G + GY + E+ +R+ R + +T L RVTGLT
Sbjct: 17334 AKDSMTVCWNRPDSDGGSEIIGYIV--EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 17391
Query: 964 YTIEVAAMTSKGQGQVSASTI--SSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGK 1020
Y V+A + G G+ S +T+ + P PGPPTN I + S+TL + +P YDG
Sbjct: 17392 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 17451
Query: 1021 TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG-- 1078
+ I ++VE + EEW ++ + R E+ L Y R+ +N VG
Sbjct: 17452 SEILGYVVEI---CKADEEEWQIVTPQTGLRVTR-FEISKLTEHQEYKIRVCALNKVGLG 17507
Query: 1079 --TSPPS--QPSRKIQTLQAPPDM-APANVSLRTASETSLWLRWMPLPEMEYNGNPESVG 1133
TS P +P K++ + D + +R + + + G P
Sbjct: 17508 EATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARI--------HIPFKGRPTP-- 17557
Query: 1134 YKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
+I +SR +G + + +I++ + + ++ N+ GS TV
Sbjct: 17558 -EITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTV--- 17613
Query: 1194 TRESVPSSG-PTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWL 1252
+ + + G P N++ S + W E P D V Y + +K T+ +
Sbjct: 17614 --KVLDTPGPPQNLAVKEVRKDSAFLVW-EPPIIDGGAKVKNYVI---DKRESTRKAYAN 17667
Query: 1253 VEGNSSR-SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPE 1311
V S+ S ++ L + +Y +V+A G G P + + P PP + +
Sbjct: 17668 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-PSPPGKVTLTD 17726
Query: 1312 VRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESV 1370
V TS L+W+ P G +L Y + + T + E +A TGL
Sbjct: 17727 VSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNA---VVTGLSSGQE 17783
Query: 1371 YLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL----------- 1419
Y FR+ A KG + V K QP + ++A L
Sbjct: 17784 YQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPR 17843
Query: 1420 --LSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVK 1477
+SW DG P++ T E + LH N F K+ V
Sbjct: 17844 PNISWV--KDG-EPLKQTTRVNVEETATSTVLHIK--EGNKDDF----------GKYTVT 17888
Query: 1478 ATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGF 1537
ATN G + +E + + P P + V+I W+PPA
Sbjct: 17889 ATNSAGTA--TENLSVIVLEKPGPPVGPVRFDEV--SADFVVISWEPPA----------- 17933
Query: 1538 RIRYRELLYEG---LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRR 1594
Y G + + + + TW +++ + T ++ L
Sbjct: 17934 --------YTGGCQISNYIVEKRDTTTTTWHMVSATVAR--------TTIKITKLKTGTE 17977
Query: 1595 YEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV-VVHGATATQLDVTWEPPPLDSQN 1653
Y+ R+ N G+ + V V P V + Q+ V W P D
Sbjct: 17978 YQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG-G 18036
Query: 1654 GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST 1713
I GY + E + L ++ + + K L Y V+A N G G S
Sbjct: 18037 TKIIGYHLEQKE-KNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18095
Query: 1714 PTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSK 1772
++ + P + +T +V + W+ P + G + GY + E DG +
Sbjct: 18096 VSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGY--IVEKKDLPDG--R 18151
Query: 1773 IVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK----TFTYGPEIEANVTTGPGEGAPGPP 1828
+ V L E Y FR+ A+ F+ + +T AP
Sbjct: 18152 WMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNAS 18211
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
P +Y I +H +G+ +V+EA + + D++ KE+ M+
Sbjct: 18212 LDP---KYKDVIVVH--AGE-------TFVLEADIRGKPIPDVVWSKDGKELEETAARME 18259
Query: 1889 I 1889
I
Sbjct: 18260 I 18260
Score = 139 bits (350), Expect = 3e-32
Identities = 336/1554 (21%), Positives = 565/1554 (36%), Gaps = 218/1554 (14%)
Query: 378 FQCFARNAAGEVQ---TSTYLAVTSIAPN----ITRGPLDSTVID-GMSVVLACETSGAP 429
F+ A N AGE + T+ + T I I G D V G + + G P
Sbjct: 9282 FRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRP 9341
Query: 430 RPAITWQ---KGERILASGSVQLPRFTPLE----SGSLLISPTHISDAGTYTCLATNSRG 482
P +W+ K ++ + G +P LE S ++I S G Y+ A N G
Sbjct: 9342 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 9401
Query: 483 VDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVT-----HDPRVTIR-YIWEKDGA 536
A+ + V + PP+D V T+ S C ++ D I+ Y+ EK
Sbjct: 9402 QKTANCRVKVMD---VPGPPKDLKVSDITRGS--CRLSWKMPDDDGGDRIKGYVIEK--R 9454
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRV-----ISAGGNDSRSAHLRVRQLPH 591
T+ ++ ++ D + + + Y RV G R +
Sbjct: 9455 TIDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIY 9513
Query: 592 APEHPVAT-LSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLA-----SVD 644
P+ P+ + + + ++L+W P DG SP+ YI+E + T A D
Sbjct: 9514 PPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9573
Query: 645 PKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSK-----DTERVSLPE--------EPPT 691
+ TV+ LV Y+FR+ AVN G + S D +R +P E
Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9633
Query: 692 APPQNVIASGRTNQSIMIQW-QPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVN 750
N++A + + W + PP+ N PV Y D VN
Sbjct: 9634 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-------------PVLY------DTHVN 9674
Query: 751 NLLLED---LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ--GVPTVPPGNVHAEATNS 805
L+++D L+I + + Y + + E L G P P G + E+ ++
Sbjct: 9675 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSA 9734
Query: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFT 865
+ +W P + G K+ + E+ E + + + L +
Sbjct: 9735 DQMTLSWFPPKD------DGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGH 9788
Query: 866 EYFTSVLCFTTPGDGPR--STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG 923
EY ++ G G S P+ R VPG + S + S+ V+W+EP G
Sbjct: 9789 EYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGG 9848
Query: 924 I-LTGYRIS--------WEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSK 974
+TGY + W+ NR + + + Y+VTGL + Y V A+ +
Sbjct: 9849 SPVTGYWLEMKDTTSKRWKRVNRDPIKAM----TLGVSYKVTGLIEGSDYQFRVYAINAA 9904
Query: 975 GQGQVS--ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGY-DGKTSISRWLVEAQ 1031
G G S + ++ P PGPP +++ S L++ P DG + ++ ++VE +
Sbjct: 9905 GVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK 9963
Query: 1032 VGVVGEG-EEWLLIHQLSNEPDAR--SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRK 1088
EG EEW + + + R + V L Y FR+R VNI G P + +
Sbjct: 9964 ----EEGKEEW----EKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV 10015
Query: 1089 IQ---TLQAPPDMAPANVSLRTASETS------LWLRWMPLPEMEYNGNPESVGYKIKYS 1139
I+ L +P A+V R ++ P P + +N N ++ +
Sbjct: 10016 IEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE---- 10071
Query: 1140 RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVP 1199
+ + + I++ + + + A N +G +T++ + VP
Sbjct: 10072 ---------ATIETTAISSSMVIKNCQRSHQGVYSLLAKNE--AGERKKTIIVDVLD-VP 10119
Query: 1200 SSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW--LVEGNS 1257
T A T+ S + W PE D + Y + +E D R W + +
Sbjct: 10120 GPVGTPFLAHNLTNESCKLTWFS-PEDDGGSPITNYVIEKRESDR----RAWTPVTYTVT 10174
Query: 1258 SRSAQLTGLGKYVLYEVQVLAFTRIGDGS--PSHPPILERTLDDVPGPPMGILFPEVRTT 1315
++A + GL + Y ++ A IG G + ++ R VP P + EV
Sbjct: 10175 RQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKN 10234
Query: 1316 SVRLIWQPPAAPNGI-ILAYQITHRL-NTTTANTATVEVLAPSARQYTATGLKPESVYLF 1373
+V L W PP G I+ Y + RL T + T + L +R+YT GLK Y +
Sbjct: 10235 TVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLL--SRKYTVKGLKEGDTYEY 10292
Query: 1374 RITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVR 1433
R++A G G+ + T K D PP+ + D R + L+ G R
Sbjct: 10293 RVSAVNIVGQGKPSFCTKPITCK-DELAPPTLHL----DFRDK---LTIRVGEAFALTGR 10344
Query: 1434 YYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATND------IGDSEF 1487
Y + P W A V + + I K + K ++ + +S
Sbjct: 10345 Y---SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401
Query: 1488 SEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYE 1547
S + + P +S T ++I W+PP +D + + I +E+ +
Sbjct: 10402 SRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG-GSKITNYIIEKKEVGKD 10460
Query: 1548 GLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGE 1607
W +T S + T ++ L + + Y R+ N G
Sbjct: 10461 ---------------VWMPVT--------SASAKTTCKVSKLLEGKDYIFRIHAENLYGI 10497
Query: 1608 GPSSPPQEVFVGE--AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWE 1665
+ + VP AP +V T VTW P I Y + E
Sbjct: 10498 SDPLVSDSMKAKDRFRVPD-APDQPIVTEVTKDSALVTWNKP--HDGGKPITNYILEKRE 10554
Query: 1666 AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG---PRSTPTQGQTQQA 1722
K ++ +L Y V+A N G G P S P + A
Sbjct: 10555 TMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIA 10614
Query: 1723 APSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGN 1781
PS P + + + T SV+++W+ P+ G + GY + Y+ D + +
Sbjct: 10615 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVG--DEEWRRANHTPESC 10672
Query: 1782 SPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVR 1835
KV L +G TY+FR+ A GE P P++V+
Sbjct: 10673 PETKYKVTGLRDGQTYKFRVLA-------------VNAAGESDPAHVPEPVLVK 10713
Score = 138 bits (347), Expect = 7e-32
Identities = 278/1273 (21%), Positives = 477/1273 (37%), Gaps = 148/1273 (11%)
Query: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI-TDADVNN 751
PPQ++ T S+ + W PP + I K YI+ + + + T+ +
Sbjct: 15457 PPQDLKVKEVTKTSVTLTWDPPLLDGGSKI-KNYIVEKRESTRKA---YSTVATNCHKTS 15512
Query: 752 LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
++ L +Y V A N G+G+ ++ E +PPG + ++ +
Sbjct: 15513 WKVDQLQEGCSYYFRVLAENEYGIGL-PAETAESVKASERPLPPGKITLMDVTRNSVSLS 15571
Query: 812 WNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSV 871
W P + I GY + ++ T T + + ++GL + EY V
Sbjct: 15572 WEKPEHDGGSRI-LGYIVEMQTKGSDKWATCATVK------VTEATITGLIQGEEYSFRV 15624
Query: 872 LCFTTPG-DGPRSTPQLVRTHEDVPGPVGHL---SFSEILDTSLKVSWQEPGEKNGILTG 927
G PR V + V P L +F+ + LKV G +T
Sbjct: 15625 SAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTW 15684
Query: 928 YR--ISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
++ + ++ R N T N L + + Y +++ S G+ + + I
Sbjct: 15685 HKDNVPLKQTTRVNAESTEN--NSLLTIKDACREDVGHYVVKLT--NSAGEAIETLNVIV 15740
Query: 986 SGVPPELPGPPTN-LGISNIGPRSVTLQFRPG-YDGKTSISRWLVEAQVGVVGEGEEWLL 1043
+ PGPPT + + + S+TL + P YDG +SI+ ++VE + +
Sbjct: 15741 L----DKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR-------DTSTT 15789
Query: 1044 IHQLSNEPDARS-MEVPDLNPFTCYSFRMRQVNIVGTSP--PSQPSRKIQTLQAPPDMAP 1100
Q+ + AR+ ++ L Y FR+ N G S S+P+ + P
Sbjct: 15790 TWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGT 15849
Query: 1101 ANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV---E 1157
V+L +S S+ ++W E +G +GY ++ + ++ V ++ +
Sbjct: 15850 PVVTL--SSRDSMEVQWN---EPISDGGSRVIGYHLERKERN----SILWVKLNKTPIPQ 15900
Query: 1158 RDYTIEDLEEWTEYRVQVQAFNAIGSGP---WSQTVVGRTRESVPSSGPTNVSALATTSS 1214
+ LEE EY +V A N +G G S+ V R P P A+ T +
Sbjct: 15901 TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD----PCDPPGRPEAIIVTRN 15956
Query: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA---------QLTG 1265
S+ ++W + P D + GY V KE L EG +++ ++TG
Sbjct: 15957 SVTLQWKK-PTYDGGSKITGYIVEKKE----------LPEGRWMKASFTNIIDTHFEVTG 16005
Query: 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI---WQ 1322
L + YE +V+A G S T D PP + P+ + T V ++
Sbjct: 16006 LVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFK 16065
Query: 1323 PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
A G + + + +NTA +E+ + AT L + K
Sbjct: 16066 VDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF----ATSLSVKDAVRVDSGNYILKA 16121
Query: 1383 WGEAAE-ALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSPVRYYTIQTR 1440
A E ++ V + DRP PP P+V V A L+W+P DG S + Y ++ R
Sbjct: 16122 KNVAGERSVTVNVKVLDRPGPPEGPVVIS-GVTAEKCTLAWKPPLQDGGSDIINYIVERR 16180
Query: 1441 ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA 1500
E W + A+V S V +L Y FR+ A N G E E +
Sbjct: 16181 ETSRLVWTVVDANVQ--TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFV 16238
Query: 1501 PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 1560
+AP VT T S+++ W+ PA D + IL G+ L +
Sbjct: 16239 VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL----------------GYVLEKRDKE 16282
Query: 1561 GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ--EVFV 1618
G W R + L + L ++ YE R+S NA G SPP +
Sbjct: 16283 GIRWTRC----HKRLIGELRL---RVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKAC 16335
Query: 1619 GEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTL 1678
P N V T + + ++W P D +IQGY + + G T
Sbjct: 16336 DPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG-GCEIQGYIVEKCDVSVGEWTMCTPPT 16394
Query: 1679 FLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTT 1738
+ + +++++ L Y + A N AG G + A P V+ +L
Sbjct: 16395 GINKTNIEVEKLLEKHEYNFRICAINKAGVG----------EHADVPGPIIVE-EKLEAP 16443
Query: 1739 SVNVSWEAPQFPNGILEGYRLVYEPC----------SPVDG-VSKIVTVDVKGN-SPLWL 1786
+++ E + N G ++ P VDG + +DV + + L L
Sbjct: 16444 DIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 16503
Query: 1787 KVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSS 1846
+ + Y + + T + V P P + + +++I W
Sbjct: 16504 DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSP----PVNLKVTEITKDSVSITWEP 16559
Query: 1847 G-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVND 1905
G I Y++E R + + ++ + K ++ +D L+ G SY FRV A N+
Sbjct: 16560 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKN----SWKIDQLQEGCSYYFRVTAENE 16615
Query: 1906 YGFGTPSSPSQSV 1918
YG G P+ + +
Sbjct: 16616 YGIGLPAQTADPI 16628
Score = 130 bits (326), Expect = 2e-29
Identities = 330/1569 (21%), Positives = 558/1569 (35%), Gaps = 197/1569 (12%)
Query: 222 KNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGV-LLSGGISDHNRR---LTIPNPTGS 277
K ++ AG S + V+ P + I W K G+ L S I D L +
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPV---ITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 23013
Query: 278 DAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV-DIPCQAKGVP 336
DAG Y EA +S + V P VK E ++ + + +IP G P
Sbjct: 23014 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE--VSRDSVTITWEIPTIDGGAP 23071
Query: 337 PPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLA 396
+ K A + K T + + +ISGLV F+ N G +
Sbjct: 23072 VNNYIVEKREAAMRAFK-TVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE--- 23127
Query: 397 VTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA-------SGSVQL 449
TS A ++ PL ++ + V + T +P + G R+ +G+ +
Sbjct: 23128 -TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPL--YDGGSRLTGYVLEACKAGTERW 23184
Query: 450 PRFTPLESGSLLISPTHISDAGTYT--CLATNSRGVDEASA--------DLVVWARTRIT 499
+ L+ L + T +++ Y A N +GV E DL V ++
Sbjct: 23185 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23244
Query: 500 KPPQDQ-SVIKGTQASMVCGVTHDPRVTIRYIWE----KDGATLGTESHPRIRLDRNGSL 554
PQ V G +V + P + + ++ + E+H ++ L
Sbjct: 23245 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV-----AKL 23299
Query: 555 HISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTK 614
I +T D G YT + + G S + + + P P P+ + ++ +I ++W
Sbjct: 23300 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIK-IDEIDATSITISWEP 23358
Query: 615 P-FDGNSPLIRYILEMSENNAP-WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVG 672
P DG +PL Y++E + + P W + SV T L Y FR+ A N G
Sbjct: 23359 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFG 23416
Query: 673 KGQFSKDT-----ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYI 727
G + + + +P P T +V G T + W PP E + GYI
Sbjct: 23417 IGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMT-----LTWYPP-EDDGGSQVTGYI 23470
Query: 728 IRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTL 787
+ + + + L YE V A N+ G G S+ ++ +
Sbjct: 23471 VERKEVRADRWVRVNKVP-VTMTRYRSTGLTEGLEYEHRVTAINARGSGK-PSRPSKPIV 23528
Query: 788 QGVPTVPPG---NVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT 844
P PPG N T T++ W+ P + + + GY LI + + E T
Sbjct: 23529 AMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVT-GY-LIEMQKVDQHEWTKCN 23586
Query: 845 ARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFS 904
P I ++ L + EY VL G G + +VPG V
Sbjct: 23587 TTPT---KIREYTLTHLPQGAEYRFRVLACNAGGPGEPA---------EVPGTVKVTEML 23634
Query: 905 EILDTSLKVSWQE----------------PGEKNGILTGYRISWEEYNRTNTRVTHYLPN 948
E D L +QE G+ I + + R +
Sbjct: 23635 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE 23694
Query: 949 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRS 1008
+ ++ G + TY + + K + I S PE P L +I RS
Sbjct: 23695 LVIKEADRGDSG--TYDLVLENKCGKKAVYIKVRVIGSPNSPEGP-----LEYDDIQVRS 23747
Query: 1009 VTLQFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
V + +RP DG I +++E + W + + + S+ V L Y
Sbjct: 23748 VRVSWRPPADDGGADILGYILERREVPKAA---W---YTIDSRVRGTSLVVKGLKENVEY 23801
Query: 1068 SFRMRQVNIVGTSPPSQPSRKI--QTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY 1125
FR+ N G S P + + +T PP+ + +++S+ L W +
Sbjct: 23802 HFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD--- 23858
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG--- 1182
+G GY I+ + K + H YT+ L EY+ ++ A N +G
Sbjct: 23859 DGGSRVTGYYIE-RKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSE 23917
Query: 1183 SGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEK 1242
+ P S+ VV + PS P + L+ + S+ ++W E PE D +LGY V Y++
Sbjct: 23918 TSPASEPVVCKDPFDKPSQ-PGELEILSISKDSVTLQW-EKPECDGGKEILGYWVEYRQS 23975
Query: 1243 DSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT-LDDVP 1301
D+ + E + + GL + YE +V A G P + +T L
Sbjct: 23976 -GDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGE 24034
Query: 1302 GPPMGILFPEVRTT---SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P + +V T + +L Q P I Y+ L + ++ R
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-----MSSDGR 24089
Query: 1359 QYTATGL--KPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416
+T T + + E ++ A G E + L++ + P P +
Sbjct: 24090 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYY------- 24142
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSY---- 1472
G+ G + + R +P+ W H + N+ + ++ + +T
Sbjct: 24143 --------GAVGSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKN 24193
Query: 1473 --------KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQP 1524
K++V+ +N G + + E +Q PD+ + + S +I W+P
Sbjct: 24194 VQRKTHAGKYKVQLSNVFGTVDAILDVE----IQDKPDKPTGPIVIEALLKNSAVISWKP 24249
Query: 1525 PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY 1584
PA+D + + + E GA W ++S S+T
Sbjct: 24250 PADDG-GSWITNYVVEKCEA--------------KEGAEWQLVSSAI--------SVTTC 24286
Query: 1585 ELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT-----AAPRNVVVHGATATQ 1639
+ NL ++ Y R+S N G S P EV + + AP + T
Sbjct: 24287 RIVNLTENAGYYFRVSAQNTFG---ISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24343
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
V W+PP D I+ Y + E ++ N V T + E +KNL Y
Sbjct: 24344 CVVAWKPPASDG-GAKIRNYYLEKRE-KKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 24401
Query: 1700 VAAFNAAGD 1708
V N G+
Sbjct: 24402 VKCENLGGE 24410
Score = 128 bits (321), Expect = 7e-29
Identities = 170/673 (25%), Positives = 261/673 (38%), Gaps = 90/673 (13%)
Query: 1299 DVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
DVPGP + E V L W+ P G + + R + A S
Sbjct: 6591 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 6649
Query: 1359 QYTATGLKPESV-YLFRITAQTRKGWGEAAEA--LVVTTEKRDRPQPPSRPMVQQEDVRA 1415
++T TGL+ V YLFR++A+ R G GE E V K D P PP + DV
Sbjct: 6650 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT--DVNR 6707
Query: 1416 RSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
V L+WEP DG + + Y I+ R+ S RW + + S+ + D ++ Y F
Sbjct: 6708 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEG-QEYSF 6766
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRWQPPAEDKINGI 1533
RV+A N IG + S + + +P + L+ + T +SV ++W+PP +D + I
Sbjct: 6767 RVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPI 6826
Query: 1534 LLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHR 1593
L G+ + W P LT Y++ L K
Sbjct: 6827 L----------------GYIIERCEEGKDNWIRCNMKLV------PELT-YKVTGLEKGN 6863
Query: 1594 RYEIRMSVYNAVGEGPSSP------PQEVFVGEAVPTAAPRN---VVVHGATATQLDVTW 1644
+Y R+S N G S + FV + +A ++ V+V + T
Sbjct: 6864 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 6923
Query: 1645 EPPPLDSQN-GDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAF 1703
P P + GD K L + VK+K L+ Y ++S +
Sbjct: 6924 YPRPTATWCFGD--------------------KVLETGDR-VKMKTLSAYAELVISPSER 6962
Query: 1704 NAAGDGPRSTPTQGQTQQ--------AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-L 1754
+ G + +T A PSAP +KF ++T SV+++WE P G L
Sbjct: 6963 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7022
Query: 1755 EGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP---- 1810
GY + S K T + + L V DL +G Y F++ A+ GP
Sbjct: 7023 TGYVVEKREVS-----RKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARN-KCGPGEPA 7076
Query: 1811 EIEANVTTGPGEGAPGPP-GVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGL 1868
++ V P PP V R +++I + W + G I Y++E P
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7136
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYE 1928
W + V+ + L+ G Y +RV A+N G PS P++ + A E
Sbjct: 7137 W----VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7192
Query: 1929 EWWFLVVIALVGL 1941
FL V L GL
Sbjct: 7193 --IFLDVKLLAGL 7203
Score = 127 bits (320), Expect = 9e-29
Identities = 317/1464 (21%), Positives = 519/1464 (35%), Gaps = 187/1464 (12%)
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP---LDSTVID------G 416
++ GL+ + F+ A N GE + LA + IA +I P LD T D G
Sbjct: 11368 RVPGLIEGNEYRFRIKAANIVGEGEPRE-LAESVIAKDILHPPEVELDVTCRDVITVRVG 11426
Query: 417 MSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
++ + G P P ITW K ++L ++ L L I +D G Y
Sbjct: 11427 QTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11485
Query: 477 ATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 536
A NS G + SA + V R P Q+ V T+ + C ++ WE
Sbjct: 11486 AKNSSGHAQGSAIVNVLDR---PGPCQNLKVTNVTKEN--CTIS----------WENPLD 11530
Query: 537 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV---RQLPHAP 593
G+E I R + + WS T R+I A + + RV ++ P
Sbjct: 11531 NGGSEITNFIVEYRKPN---QKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGP 11587
Query: 594 ----EHPVATLSTVERRA--------------INLTWTKP-FDGNSPLIRYILEMSENNA 634
+ P+ ++ ++R + L W +P +DG SP + Y +E +
Sbjct: 11588 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11647
Query: 635 PWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE---PPT 691
+ K T V V + Y+FR+ N+ G+ + K TE V + E+ P
Sbjct: 11648 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TEEVVVKEDLQKPVL 11706
Query: 692 APPQNVIASGRTNQSIM----IQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
+ + + + +I ++ +P PE + L + K T A
Sbjct: 11707 DLKLSGVLTVKAGDTIRLEAGVRGKPFPE-------VAWTKDKDATDLTRSPRVKIDTRA 11759
Query: 748 DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
D + L + V A N+AG V + V G P N+ +S
Sbjct: 11760 DSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG----PVRNLKIVDVSSDR 11815
Query: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
W+ P + G ++ + E+ E MV + + V+ L + EY
Sbjct: 11816 CTVCWDPPED------DGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY 11869
Query: 868 FTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG-I 924
V G GP S P + +T D PG +++ + V W P G
Sbjct: 11870 IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKS 11929
Query: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS--AS 982
+TGY + +E + T + +V L Y V A G G+ S +
Sbjct: 11930 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 11989
Query: 983 TISSGVPPELPGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVE--AQVGVVGEGE 1039
+ + P E PGPPTN + + S+TL + +P YDG I ++VE ++ E
Sbjct: 11990 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDE 12049
Query: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
W + + + + V L+ Y FR+ N VG P++ I+ + +
Sbjct: 12050 GWKRCNAAA-QLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI---LE 12105
Query: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD 1159
P + L + + +R G P + ++ G+ V +V D
Sbjct: 12106 PPEIDLDASMRKLVIVR---------AGCPIRLFAIVR-------GRPAPKVTWRKVGID 12149
Query: 1160 YTIE----DLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRES--------VPSSGP-TNV 1206
+ DL + + V + SG +S T+V E + + GP +++
Sbjct: 12150 NVVRKGQVDLVDTMAFLV-IPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 12208
Query: 1207 SALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGL 1266
T +S V W+ PE D V Y V +E D T + S +T L
Sbjct: 12209 KVSDVTKTSCHVSWAP-PENDGGSQVTHYIVEKREADRKTWST--VTPEVKKTSFHVTNL 12265
Query: 1267 GKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
Y +V A G G P+ P+L P PP + E+ S L W PP
Sbjct: 12266 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 12325
Query: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
G + IT E TGLK Y FR+ A+ G
Sbjct: 12326 LRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS 12385
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL-------------LSWEPGSDGLSP 1431
EA V E +++ PP M +Q ++A L W+ G D +
Sbjct: 12386 LPREAEGV-YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEV-- 12442
Query: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491
+ S A+H A ++S I+ + S + + A N G ++
Sbjct: 12443 ----------VTSSHLAVHKAD---SSSILIIKDVTRKDSGYYSLTAENSSG----TDTQ 12485
Query: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG 1551
+ + AP ++ + + W P ED + I
Sbjct: 12486 KIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNI----------------TN 12529
Query: 1552 FTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG--EGP 1609
+ + + W +T++ S+ + T + L + Y R+ N G E
Sbjct: 12530 YIVEKCDVSRGDW--VTALASV------TKTSCRVGKLIPGQEYIFRVRAENRFGISEPL 12581
Query: 1610 SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQR 1668
+SP VP + P+N V + V W+ P DS G I GY I E +
Sbjct: 12582 TSPKMVAQFPFGVP-SEPKNARVTKVNKDCIFVAWDRP--DSDGGSPIIGYLIERKE-RN 12637
Query: 1669 GNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPS 1728
L + + L Y + A N AG P S PT+ T + P
Sbjct: 12638 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG 12697
Query: 1729 SVKFSELTTTSVNVSWEAPQFPNG 1752
+ ++T ++V++ W P+ G
Sbjct: 12698 KPEVIDVTKSTVSLIWARPKHDGG 12721
Score = 127 bits (319), Expect = 1e-28
Identities = 190/818 (23%), Positives = 304/818 (37%), Gaps = 69/818 (8%)
Query: 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER-DYTIEDLEEW-TEYRVQVQAFNAIGS 1183
+G + +GY ++ R D KT + DR E ++T+ L++ EY +V A N +G+
Sbjct: 6619 DGGSKIIGYVVE--RRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGT 6675
Query: 1184 GPWSQT---VVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYK 1240
G +T V R++ VP P NV+ + + W E PE D + Y + +
Sbjct: 6676 GEPVETDNPVEARSKYDVPGP-PLNVTITDVNRFGVSLTW-EPPEYDGGAEITNYVIELR 6733
Query: 1241 EKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDV 1300
+K S V SA +T + + Y +V A RIG G PS + D +
Sbjct: 6734 DKTSIRWDTAMTVRAEDL-SATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPI 6792
Query: 1301 --PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSAR 1358
P PP+ + + +SV+L W+PP G + I R N +
Sbjct: 6793 ERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPEL 6852
Query: 1359 QYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQE--DVRAR 1416
Y TGL+ + YL+R++A+ + G + +E L T +P ++ +V
Sbjct: 6853 TYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVP 6912
Query: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSG-RWALHSASVSHNASSFIVDRLKPFTSYKFR 1475
+ + P + P + + L +G R + + S + ++ + +
Sbjct: 6913 NPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAY---AELVISPSERSDKGIYT 6969
Query: 1476 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 1535
+K N + S + A AP L T SV + W+PP +D L
Sbjct: 6970 LKLENRV-----KTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDG-GSPLT 7023
Query: 1536 GFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRY 1595
G+ + RE+ + TW ++ + + P L Q + Y
Sbjct: 7024 GYVVEKREVSRK---------------TWTKVMDFVTDLEFTVPDLVQ--------GKEY 7060
Query: 1596 EIRMSVYNAVGEGPSS---PPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQ 1652
++ N G G + P + VP P NV TA + +TW+PP D
Sbjct: 7061 LFKVCARNKCGPGEPAYVDEPVNMSTPATVPDP-PENVKWRDRTANSIFLTWDPPKNDG- 7118
Query: 1653 NGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712
I+GY + RG+ +AE +++ L Y V A N G S
Sbjct: 7119 GSRIKGYIVE--RCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPS 7176
Query: 1713 TPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDG 1769
PT Q Q AP VK T E P G E ++ + +
Sbjct: 7177 RPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP-KITWTKADMILK 7235
Query: 1770 VSKIVTVD-VKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPP 1828
K +T++ V S + + ++ TY +E NV PG P
Sbjct: 7236 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGP----PA 7291
Query: 1829 GVPIIVRYSSAIAIHWSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSM 1887
I + + + W+ D G IT YV+E R +D +W L V F
Sbjct: 7292 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL----SSTVKDTNFKA 7347
Query: 1888 DILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
L P Y FRV A N YG G P S + +P
Sbjct: 7348 TKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDP 7385
Score = 124 bits (311), Expect = 1e-27
Identities = 299/1315 (22%), Positives = 478/1315 (36%), Gaps = 170/1315 (12%)
Query: 683 VSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK 742
VS+ + P PP N + S++ +W+PP + + I I Y L + K
Sbjct: 8299 VSVLDTP--GPPINFVFEDIRKTSVLCKWEPPLDDGGSEI-----INYTL-------EKK 8344
Query: 743 NITDADVNNLLLED-----------LIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQG 789
+ T D +++ LI Y V A N G G S + G
Sbjct: 8345 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFG 8404
Query: 790 VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN- 848
P P + + T+++ + WN P + G ++ + E+ E + +R N
Sbjct: 8405 PPDAPDKPIVEDVTSNSML-VKWNEPK-------DNGSPILGYWLEKREVNSTHWSRVNK 8456
Query: 849 -FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEIL 907
+++ V GL + Y V G G S P +T D P G +
Sbjct: 8457 SLLNALKAN-VDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGP-PIPRVT 8514
Query: 908 DTS---LKVSWQEPG-EKNGILTGYRISWEEYNRTN--TRVTHYLPNVTLEYRVTGLTAL 961
DTS +++ W+ P G + GY + ++ TN +R T + V +Y V +
Sbjct: 8515 DTSSTTIELEWEPPAFNGGGEIVGYFVD-KQLVGTNEWSRCTEKMIKVR-QYTVKEIREG 8572
Query: 962 TTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV----TLQFRPGY 1017
Y + V+A+ + G+G + + P+ P P L +S G + TL+
Sbjct: 8573 ADYKLRVSAVNAAGEGPPGETQPVTVAEPQEP-PAVELDVSVKGGIQIMAGKTLRIPAVV 8631
Query: 1018 DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G+ V +V EGE + N + + D + + N
Sbjct: 8632 TGRP------VPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSC 8685
Query: 1078 GTSPPSQPSRKIQTLQAPP---DMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY 1134
G+ + +++ P D+ P + L W + E +G E G+
Sbjct: 8686 GSK---FAAARVEVFDVPGPVLDLKPV-----VTNRKMCLLNWS---DPEDDGGSEITGF 8734
Query: 1135 KIKYSRSDGHGKTLSHVVQ-DRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR 1193
I+ R D T ++ +R + D T L E EY+ +V A N G GP +G
Sbjct: 8735 IIE--RKDAKMHTWRQPIETERSKCDIT--GLLEGQEYKFRVIAKNKFGCGP--PVEIGP 8788
Query: 1194 TRESVPSSGPTNVSALA---TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRF 1250
P PT+ L T S++ + W E P ++ + GY + EK +P F
Sbjct: 8789 ILAVDPLGPPTSPERLTYTERTKSTITLDWKE-PRSNGGSPIQGYII---EKRRHDKPDF 8844
Query: 1251 WLVEGN--SSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGIL 1308
V + S + L ++ +YE +V A IG+ PS P L + D PP L
Sbjct: 8845 ERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLP--LNVVIQDDEVPPTIKL 8902
Query: 1309 FPEVRTTSVRL-IWQP---PAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG 1364
VR ++++ +P PA G+ + +I N T T + L + + + +
Sbjct: 8903 RLSVRGDTIKVKAGEPVHIPADVTGLPMP-KIEWSKNETVIEKPT-DALQITKEEVSRSE 8960
Query: 1365 LK-----PESVY----LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRA 1415
K P++V + +TA R G + V E DRP PP V D++A
Sbjct: 8961 AKTELSIPKAVREDKGTYTVTASNRLG----SVFRNVHVEVYDRPSPPRNLAVT--DIKA 9014
Query: 1416 RSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S L+W+ P +G S + +Y I R+ + + + + + +L P Y+F
Sbjct: 9015 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 9074
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGIL 1534
RV+A N G S+ + + + P V T S+L+ W PP D +
Sbjct: 9075 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSPI 9133
Query: 1535 LGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSL--TQYELDNLNKH 1592
G+ + RE EG + S S +++ L ++ + L +
Sbjct: 9134 TGYWLEKRE---EG----------------SPYWSRVSRAPITKVGLKGVEFNVPRLLEG 9174
Query: 1593 RRYEIRMSVYNAVGEGPSSPPQ--EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
+Y+ R NA G GP S P EV P P V T + + + W+PP D
Sbjct: 9175 VKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKD 9234
Query: 1651 SQNGDIQGYKIYFWE---AQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG 1707
I+GY + E + E K + E V NL Y V A N AG
Sbjct: 9235 G-GSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVV--PNLKELRKYRFRVKAVNEAG 9291
Query: 1708 DGPRSTPT---QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPC 1764
+ S T Q P + + P G R +
Sbjct: 9292 ESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG-----RPTPKSS 9346
Query: 1765 SPVDGVSKIVTVDVKGNSP-----------LWLKVKDLAEGVTYRFRIRAKTFTYGPEIE 1813
DG +K D + P + + + T ++ I AK
Sbjct: 9347 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 9406
Query: 1814 ANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS-SGDPGKGPITRYVIEARPSDEGLWDIL 1872
V G P V I R S ++ W D G I YVIE R D W
Sbjct: 9407 CRVKVMDVPGPPKDLKVSDITRGSCRLS--WKMPDDDGGDRIKGYVIEKRTIDGKAW--- 9461
Query: 1873 IKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFY 1927
+ + S TF + L Y FRV A N +G G P Q A+ +P Y
Sbjct: 9462 -TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR--DPIY 9513
Score = 122 bits (307), Expect = 3e-27
Identities = 293/1394 (21%), Positives = 498/1394 (35%), Gaps = 169/1394 (12%)
Query: 590 PHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKAT 648
P P P T T + + +L W+ P DG S + YI+E E + + T
Sbjct: 9924 PPGPPFPKVTDWT--KSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 9981
Query: 649 SVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIM 708
+ V GL Y+FR+ AVN G G+ + T+ + + + +P + AS R +
Sbjct: 9982 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-VSPDLQLDASVRDRIVV- 10039
Query: 709 IQWQPPPESHQNGILKGYIIRYCLAGLP---VGYQFKNIT---DADVNNLLLEDLIIWTN 762
H G+++ II Y ++G P V + T +A + + ++ N
Sbjct: 10040 ---------HAGGVIR--IIAY-VSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKN 10087
Query: 763 YE------IEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPS 816
+ + A N AG + V + G P P H TN + + TW +P
Sbjct: 10088 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAH-NLTNESC-KLTWFSPE 10144
Query: 817 PQFINGINQGYKLIAWEPEQEE--EVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
+ I Y + E ++ VT R N V GL + YF +
Sbjct: 10145 DDGGSPITN-YVIEKRESDRRAWTPVTYTVTRQN-------ATVQGLIQGKAYFFRIAAE 10196
Query: 875 TTPGDGP---RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG------IL 925
+ G GP S ++R VP L E+ ++ ++W P G +L
Sbjct: 10197 NSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 10256
Query: 926 TGYRISWEEYNR-TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTI 984
I E++++ TN + ++ +Y V GL TY V+A+ GQG+ S T
Sbjct: 10257 ESRLIGTEKFHKVTNDNL------LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTK 10310
Query: 985 SSGVPPELPGPPTNLGISNIGPRSVTLQFRPG--------YDGKTSISRWLVEAQVGVVG 1036
EL P +L + L R G Y GK + + V+
Sbjct: 10311 PITCKDELAPPTLHLDFRD------KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364
Query: 1037 EGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP- 1095
+ + P ++E + + N G+ + ++ + P
Sbjct: 10365 DDRT-----HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSR---KGFCQVNVVDRPG 10416
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL-SHVVQD 1154
P + P VS ++ + + W P + +G + Y I+ GK + V
Sbjct: 10417 PPVGP--VSFDEVTKDYMVISWKPPLD---DGGSKITNYIIEKKEV---GKDVWMPVTSA 10468
Query: 1155 RVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTRESVPSSGPTNVSALATT 1212
+ + L E +Y ++ A N G S P S ++ + R VP + P T
Sbjct: 10469 SAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDA-PDQPIVTEVT 10527
Query: 1213 SSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLY 1272
S LV W++ + + + Y + +E S R + ++ L + Y
Sbjct: 10528 KDSALVTWNKPHDGGKP--ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQY 10585
Query: 1273 EVQVLAFTRIGDGSPSHP--PILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
E +V A IG G PS P P+ + P PP+ + SV L WQPP G
Sbjct: 10586 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10645
Query: 1331 -ILAYQITH-RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE 1388
IL Y + + ++ A + +Y TGL+ Y FR+ A G + A
Sbjct: 10646 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 10705
Query: 1389 ALVVTTEKRDRPQPPS----RPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPS 1444
K DR +PP M +++ ++ L LS + I+ P
Sbjct: 10706 VPEPVLVK-DRLEPPELILDANMAREQHIKVGDTLR--------LSAI----IKGVPFPK 10752
Query: 1445 GRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIG------DSEFSEESESLTTLQ 1498
W A +D + + R A D G ++ ++ S+ L
Sbjct: 10753 VTWKKEDRDAPTKAR---IDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV 10809
Query: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558
P L V+ S + W+ P +D ++ + + R++
Sbjct: 10810 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDG-GSVITNYVVERRDVA------------- 10855
Query: 1559 NPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGP--SSPPQEV 1616
A W+ L++ ++ + +LN+ +Y R++ N G GP +P
Sbjct: 10856 --SAQWSPLSATSKKKS--------HFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIK 10905
Query: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVK 1676
+ P P+++ T++ + W P D I GY + E Q + +K
Sbjct: 10906 ALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDG-GSPITGYLV---EYQEEGTQDWIK 10961
Query: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRST--PTQGQTQQAAPSAPSSVKFSE 1734
+ + L Y V A N G G T P + Q + PS VK E
Sbjct: 10962 FKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIE 11021
Query: 1735 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 1794
+ P G+ S + + TV+ S + L +K+
Sbjct: 11022 GLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTVETDNFSSV-LTIKNCLRR 11079
Query: 1795 VTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSA--IAIHWSSG-DPGK 1851
T ++I + ++T PGPP PI + + + I W D G
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTV---LDVPGPPTGPINILDVTPEHMTISWQPPKDDGG 11136
Query: 1852 GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
P+ Y++E + + + W + + S + L+ G Y FRV A N G G P
Sbjct: 11137 SPVINYIVEKQDTRKDTWGV----VSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPP 11192
Query: 1912 SSPSQSVPAQKANP 1925
+ +V K +P
Sbjct: 11193 LDSTPTVAKHKFSP 11206
Score = 119 bits (299), Expect = 2e-26
Identities = 335/1620 (20%), Positives = 584/1620 (36%), Gaps = 266/1620 (16%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAK--------GVPPPSITWYKDAAVVEVEK 353
++ +EP + ++ P+ + +++K V I A G PPP ITW K +
Sbjct: 22935 IAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA 22994
Query: 354 LTRFRQRNDGGLQISGLVPD-----DTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP 408
+ D S L+ D D G + A N +G+ + + V T GP
Sbjct: 22995 II------DTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD-----TPGP 23043
Query: 409 LDSTVI-----DGMSVVLACET--SGAPRPAITWQKGER-------ILASGSVQLPRFTP 454
S + D +++ T GAP +K E + S L R +
Sbjct: 23044 CPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISG 23103
Query: 455 LESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQAS 514
L G++ + L N G+ E + + P V+ T++
Sbjct: 23104 LVEGTMYY----------FRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKS- 23152
Query: 515 MVCGVTHDPRVTIRYIWEK---DGAT-----------LGTESHPRIRLDRNGSLHISQTW 560
T+ WEK DG + GTE ++ + L + T
Sbjct: 23153 -----------TVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTS 23201
Query: 561 SGDIGTYTCRVISA---GGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFD 617
+ Y R+ + G ++ R V + P LST+ ++ I++ +P +
Sbjct: 23202 LNEGEQYLFRIRAQNEKGVSEPRETVTAVT-VQDLRVLPTIDLSTMPQKTIHVPAGRPVE 23260
Query: 618 GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGK---- 673
L+ I A W S ++ VTV+ R + D G+
Sbjct: 23261 ----LVIPIAGRPPPAASW-FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23315
Query: 674 -----GQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII 728
G S+ + + L + P P + T SI I W+PP E L GY++
Sbjct: 23316 LKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDAT--SITISWEPP-ELDGGAPLSGYVV 23372
Query: 729 RYCLAG----LPVG-------YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGV 777
A LPV ++F +T+ + Y VAA N G+G
Sbjct: 23373 EQRDAHRPGWLPVSESVTRSTFKFTRLTEGN-------------EYVFRVAATNRFGIGS 23419
Query: 778 Y-SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGY-------KL 829
Y S+V E PP + + + TW P + + GY +
Sbjct: 23420 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRA 23478
Query: 830 IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVR 889
W + VTM R +GL + EY V G G S P
Sbjct: 23479 DRWVRVNKVPVTMTRYRS-----------TGLTEGLEYEHRVTAINARGSGKPSRPSKPI 23527
Query: 890 THEDVPGPVGHLSFSEILDT---SLKVSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHY 945
D P G + DT S+ ++W P ++ G +TGY I ++ ++ +
Sbjct: 23528 VAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT 23587
Query: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLG----- 1000
P EY +T L Y V A + G G+ + + V L P L
Sbjct: 23588 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 23647
Query: 1001 ---ISNIGPRSVTLQFRPGYDGKT-SISRWLVEAQ------VGVVGEGEEWLLIHQLSNE 1050
+ G +T+ + GK I +W E Q + E L+I + ++
Sbjct: 23648 GIFVRQGGVIRLTIPIK----GKPFPICKWTKEGQDISKRAMIATSETHTELVIKE-ADR 23702
Query: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110
D+ + ++ N + ++ V ++G+ P+ P ++ ++ +R
Sbjct: 23703 GDSGTYDLVLENKCGKKAVYIK-VRVIGS--PNSPEGPLEY---------DDIQVR---- 23746
Query: 1111 TSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE-RDYTIEDLEEWT 1169
S+ + W P + +G + +GY ++ K + + RV ++ L+E
Sbjct: 23747 -SVRVSWRPPAD---DGGADILGYILERREVP---KAAWYTIDSRVRGTSLVVKGLKENV 23799
Query: 1170 EYRVQVQAFNAIG-SGPWS--QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 1226
EY +V A N G S P + V +T + P L T SS+ + WS P+
Sbjct: 23800 EYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSR-PKD 23858
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG--D 1284
D V GY + KE +D R + ++ +TGL Y+ +++A +G +
Sbjct: 23859 DGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYT-VTGLVPDAEYQFRIIAQNDVGLSE 23917
Query: 1285 GSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTT 1343
SP+ P++ + D P P + + SV L W+ P G IL Y + +R +
Sbjct: 23918 TSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGD 23977
Query: 1344 TANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE-ALVVTTEKRDRPQP 1402
+A + + +Q+T GL + Y FR+ A+ G A+ + T+ P
Sbjct: 23978 SAWKKSNKERIKD-KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP 24036
Query: 1403 PSRPMVQQEDVR-ARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF 1461
R ++ + + LS + L +++Y + S ++ + S +H +
Sbjct: 24037 GIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVM 24096
Query: 1462 IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 1521
++ + ATN++G+ E S S LQA P P
Sbjct: 24097 TEEQEDEGV---YTCIATNEVGEVETS----SKLLLQATPQFHPGY-------------- 24135
Query: 1522 WQPPAEDKINGILLGFRIRYRELLYEGLRGFTLR------GINNPGATWAELTSMY-SMR 1574
P ++K Y G G TLR G P TW + +
Sbjct: 24136 ---PLKEK----------------YYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24176
Query: 1575 NLSRPSLTQYE---LDNLNKHR---RYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPR 1628
N++ + Y + N+ + +Y++++S N G + E+ PT
Sbjct: 24177 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLS--NVFGTVDAILDVEIQDKPDKPTGP-- 24232
Query: 1629 NVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLK 1688
+V+ ++W+PP D I Y + EA+ G + V + ++ + ++
Sbjct: 24233 -IVIEALLKNSAVISWKPPA-DDGGSWITNYVVEKCEAKEGAEWQLVSSA-ISVTTCRIV 24289
Query: 1689 NLTGYTAYMVSVAAFNAAGDGPR---STPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWE 1745
NLT Y V+A N G S+ ++ P AP + +T S V+W+
Sbjct: 24290 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK 24349
Query: 1746 APQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAK 1804
P G + Y L +K ++V + VK+L EG+ Y FR++ +
Sbjct: 24350 PPASDGGAKIRNYYLEKREKKQ----NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCE 24405
Score = 115 bits (288), Expect = 5e-25
Identities = 161/653 (24%), Positives = 252/653 (38%), Gaps = 89/653 (13%)
Query: 1299 DVPGPPMGIL-FPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN--TATVEVLAP 1355
D PGPP ++ + L W P G + I + + + + TA V
Sbjct: 12493 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKT 12552
Query: 1356 SARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP---PSRPM-VQQE 1411
S R L P Y+FR+ A+ R G E +T+ K P PS P +
Sbjct: 12553 SCR---VGKLIPGQEYIFRVRAENRFGISEP-----LTSPKMVAQFPFGVPSEPKNARVT 12604
Query: 1412 DVRARSVLLSWE-PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFT 1470
V + ++W+ P SDG SP+ Y I+ +E S W + ++ + + + L
Sbjct: 12605 KVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRS-TEYPCAGLVEGL 12663
Query: 1471 SYKFRVKATNDIGDSEFSEESESLTT-LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDK 1529
Y FR+ A N G S S+ +E +T + P P ++ VT T + + W P D
Sbjct: 12664 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLI---WARPKHDG 12720
Query: 1530 INGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQ--YELD 1587
+ I+ G+ + PG W N + + Q Y
Sbjct: 12721 GSKII----------------GYFVEACKLPGDKWVRC-------NTAPHQIPQEEYTAT 12757
Query: 1588 NLNKHRRYEIRMSVYNAVGEGPSSPPQE--VFVGEAVPTAAPRNVV------VHGATATQ 1639
L + +Y+ R AV P S P + + E VP +V V T
Sbjct: 12758 GLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVC 12817
Query: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
LD T P+ + + G + E + + + TL L SV K+ YT
Sbjct: 12818 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGDYT----- 12870
Query: 1700 VAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYR 1758
+ A N++G + + + P P+SVK +++ + +SWE P G + Y
Sbjct: 12871 ITAENSSGSKSATIKLKVLDK---PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927
Query: 1759 LVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG--------P 1810
+ S + TV + S V+ L EG Y+FRI A+ YG P
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCS-----VEKLIEGHEYQFRICAEN-KYGVGDPVFTEP 12981
Query: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSA-IAIHWSS-GDPGKGPITRYVIEARPSDEGL 1868
I N PG P P+I + + + W D G PIT Y++E R +
Sbjct: 12982 AIAKNPYDPPGRCDP-----PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 13036
Query: 1869 WDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
W + + K + T L+ G Y+FRV A+N G G PS S++ A+
Sbjct: 13037 WTKVNR---KPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYAR 13086
Score = 114 bits (285), Expect = 1e-24
Identities = 351/1625 (21%), Positives = 576/1625 (35%), Gaps = 260/1625 (16%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARN 384
V+IP G P P++TW K +++ + F L I+ V D+G + ARN
Sbjct: 14588 VEIP--VLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14645
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILAS 444
GEV + V I P GP+ + V +W E
Sbjct: 14646 IVGEVGDVITIQVHDI-PGPPTGPIKFDEVSSDFV------------TFSWDPPEN---D 14689
Query: 445 GSVQLPRF----------TPLESGSLLISPTHISDAGT------YTCLATNSRGVDE--A 486
G V + + T +E + +I T+ + T + A N GV
Sbjct: 14690 GGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 14749
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
SA +V ++ PP V T+ SM H+P DG + H
Sbjct: 14750 SACIVANYPFKVPGPPGTPQVTAVTKDSMTIS-WHEPL--------SDGGSPILGYHVE- 14799
Query: 547 RLDRNGSLHISQTWS-----GDIGTYTCRVISAGGNDSRSAHLRV-------RQLPHAPE 594
R +RNG L QT S G+I S+G D + RV + P P
Sbjct: 14800 RKERNGILW--QTVSKALVPGNI------FKSSGLTDGIAYEFRVIAENMAGKSKPSKPS 14851
Query: 595 HPVATLSTVE-----------RRAINLTWTKP-FDGNSPLIRYILEMSE-NNAPWTVLLA 641
P+ L ++ R + L W KP + G + YI+E + N W
Sbjct: 14852 EPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 14911
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
S + TV GL +Y+FR+ A N G + + AP V
Sbjct: 14912 S-NILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKF 14970
Query: 702 RTNQSIM----------IQWQPPPE---SHQNGILKGYIIRYCLAGLPVGYQFKNITDAD 748
+ + + +PPP S L+G A L + I D
Sbjct: 14971 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEG------TAKLEI-----KIADFS 15019
Query: 749 VNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGNVHAEATNST 806
NL+ +D + + A N G +++ KV + P P G + S
Sbjct: 15020 -TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLD-----RPGPPEGPLAVTEVTSE 15073
Query: 807 TIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTE 866
+W P + G K+ + ++ E + + + V+ L K E
Sbjct: 15074 KCVLSWFPPLD------DGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 15127
Query: 867 YFTSVLCFTTPGDGP--RSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI 924
Y V+ G G S P L P P + + I S+ V W P G
Sbjct: 15128 YIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGS 15187
Query: 925 -LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAST 983
+ Y + + + L Y+V+GLT Y + A + G +SA +
Sbjct: 15188 EIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAG---ISAPS 15244
Query: 984 ISSGVPPEL-----PGPPTNLGISNIGPRSVTLQF-RPGYDGKTSISRWLVEAQVGVVGE 1037
+S PGPP N + + S+++ + +P YDG + I+ ++VE + E
Sbjct: 15245 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEI---ALPE 15301
Query: 1038 GEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPS--QPSRKIQTLQAP 1095
+EW ++ + A S + L Y R+ +N G P+ + K + P
Sbjct: 15302 EDEWQIVTPPAG-LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLP 15360
Query: 1096 PDM-----APANVSLRTASETSLW--LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL 1148
P++ V++R L+ ++ P PE +K++R HG++L
Sbjct: 15361 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-------------VKWARD--HGESL 15405
Query: 1149 SHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSA 1208
+IE +T + V N SG + TV S S NV
Sbjct: 15406 DKA---------SIESTSSYT--LLIVGNVNRFDSGKYILTV---ENSSGSKSAFVNVRV 15451
Query: 1209 LAT------------TSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN 1256
L T T +S+ + W + P D + Y V EK T+ + V N
Sbjct: 15452 LDTPGPPQDLKVKEVTKTSVTLTW-DPPLLDGGSKIKNYIV---EKRESTRKAYSTVATN 15507
Query: 1257 SSRSA-QLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT 1315
+++ ++ L + Y +VLA G G P+ + + P PP I +V
Sbjct: 15508 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA-SERPLPPGKITLMDVTRN 15566
Query: 1316 SVRLIWQPPAAPNGI-ILAY--QITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYL 1372
SV L W+ P G IL Y ++ + + A ATV+V + T TGL Y
Sbjct: 15567 SVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKV-----TEATITGLIQGEEYS 15621
Query: 1373 FRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-------VQQEDVRARSVLLSWEPG 1425
FR++AQ KG + + L V +D PP+ + + ED++ +
Sbjct: 15622 FRVSAQNEKGISDPRQ-LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG---- 15676
Query: 1426 SDGLSPVRYYTIQTRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGD 1484
P T +P + +++ S +N+ I D + + + VK TN G
Sbjct: 15677 ----RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGH-YVVKLTNSAG- 15730
Query: 1485 SEFSEESESLTTLQAAPDEAPT-ILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRE 1543
E E+L + PT + + T S+ + W PP D + I
Sbjct: 15731 ----EAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSI---------- 15776
Query: 1544 LLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYN 1603
+ + + TW +++ + T + L Y+ R++ N
Sbjct: 15777 ------NNYIVEKRDTSTTTWQIVSATVAR--------TTIKACRLKTGCEYQFRIAAEN 15822
Query: 1604 AVGEGP--SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKI 1661
G+ +S P VP P VV ++ ++V W P D + GY +
Sbjct: 15823 RYGKSTYLNSEPTVAQYPFKVP-GPPGTPVVTLSSRDSMEVQWNEPISDG-GSRVIGYHL 15880
Query: 1662 YFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQ 1721
E + L ++ + + K L Y V+A N G G S ++ +
Sbjct: 15881 ERKE-RNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVAR 15939
Query: 1722 AAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKG 1780
P + +T SV + W+ P + G + GY +V + P K ++
Sbjct: 15940 DPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGY-IVEKKELPEGRWMKASFTNIID 15998
Query: 1781 NSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTG--PGEGAPGPPGVPIIVRYSS 1838
+V L E Y FR+ A+ G E + +TG PP + + +Y
Sbjct: 15999 TH---FEVTGLVEDHRYEFRVIARN-AAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16054
Query: 1839 AIAIH 1843
I +H
Sbjct: 16055 TIVVH 16059
Score = 105 bits (263), Expect = 4e-22
Identities = 280/1353 (20%), Positives = 493/1353 (36%), Gaps = 159/1353 (11%)
Query: 621 PLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDT 680
P + + + +AP T V P + + ++ + L N G S
Sbjct: 10749 PFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSV-- 10805
Query: 681 ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQ 740
+V + ++P PP+++ S S + W+ P + + I + R +A Q
Sbjct: 10806 -KVLVLDKP--GPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASA----Q 10858
Query: 741 FKNIT-DADVNNLLLEDLIIWTNYEIEVAAYNSAGLG--VYSSKVTEWTLQGVPTVPPGN 797
+ ++ + + + L Y VAA N G G V + K + P PP +
Sbjct: 10859 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 10918
Query: 798 VHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF 857
+H + T + WN P + I GY L+ ++ E ++ N +
Sbjct: 10919 LHHVDVDKTEVSLVWNKPDRDGGSPIT-GY-LVEYQEEGTQDWIKFKTVTNLEC-----V 10971
Query: 858 VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVS--- 914
V+GL++ Y V G G T + E + P L I +K
Sbjct: 10972 VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTV 11031
Query: 915 ---------------WQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLT 959
W G + Y + + ++ T + + L T EY++T
Sbjct: 11032 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT-IKNCLRRDTGEYQITVSN 11090
Query: 960 ALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN-LGISNIGPRSVTLQFRPGYD 1018
A + T+ V ++PGPPT + I ++ P +T+ ++P D
Sbjct: 11091 AAGSKTVAVHLTVL-----------------DVPGPPTGPINILDVTPEHMTISWQPPKD 11133
Query: 1019 -GKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIV 1077
G + + ++VE Q + W ++ S++ +++P L Y FR+R N +
Sbjct: 11134 DGGSPVINYIVEKQDT---RKDTWGVVSSGSSKT---KLKIPHLQKGCEYVFRVRAENKI 11187
Query: 1078 GTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIK 1137
G PP + + + P P + +E + + W LP+ + G GY ++
Sbjct: 11188 GVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSD--GGSPITGYYME 11244
Query: 1138 YSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIG-SGPW-SQTVVGRTR 1195
R + GK + + + + L E Y +V A N G S P S + R
Sbjct: 11245 --RREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR 11302
Query: 1196 ESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG 1255
P P N + + + W++ P +D +LGY V ++ + R E
Sbjct: 11303 PIKPPGPPINPKLKDKSRETADLVWTK-PLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11361
Query: 1256 NSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSH--PPILERTLDDVPGPPMGILFPEVR 1313
+ ++ GL + Y ++ A +G+G P ++ + + P + + +V
Sbjct: 11362 IRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVI 11421
Query: 1314 TT----SVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPES 1369
T ++R++ + P I + ++ ++ L Q
Sbjct: 11422 TVRVGQTIRILARVKGRPEPDI-TWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 1370 VYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE-PGSDG 1428
Y+ I+A+ G + + + V DRP P V +V + +SWE P +G
Sbjct: 11481 KYI--ISAKNSSGHAQGSAIVNVL----DRPGPCQNLKVT--NVTKENCTISWENPLDNG 11532
Query: 1429 LSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 1488
S + + ++ R+ W++ ++ V+ I L Y FRV A N +G
Sbjct: 11533 GSEITNFIVEYRKPNQKGWSIVASDVTKR---LIKANLLANNEYYFRVCAENKVGVGPTI 11589
Query: 1489 EESESLTTLQAA--PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLY 1546
E + + P E P L + T V ++W+ P D L + + R
Sbjct: 11590 ETKTPILAINPIDRPGE-PENLHIADKGKTFVYLKWRRPDYDG-GSPNLSYHVERR---- 11643
Query: 1547 EGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVG 1606
L+G ++ W E S++ T Y +D +++ YE R+ N G
Sbjct: 11644 -------LKGSDD----W-ERVHKGSIKE------THYMVDRCVENQIYEFRVQTKNEGG 11685
Query: 1607 EGPSSPPQEVFVGEAVPT-------AAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGY 1659
E +EV V E + + V + V +P P + D
Sbjct: 11686 ESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDAT 11745
Query: 1660 KIYFWEAQRGNLTERVKTLFLAENS----VKLKNLTGYTAYMVSVAAFNAAGDGPRSTPT 1715
+ + RVK A++S K K G Y+V+ A N AG
Sbjct: 11746 DL--------TRSPRVKIDTRADSSKFSLTKAKRSDG-GKYVVT--ATNTAGSFVAYATV 11794
Query: 1716 QGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGV--SKI 1773
+ P ++K ++++ V W+ P+ G E + E C V +
Sbjct: 11795 NVLDK---PGPVRNLKIVDVSSDRCTVCWDPPEDDGGC-EIQNYILEKCETKRMVWSTYS 11850
Query: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGE----GAPGPP 1828
TV G + V L EG Y FR+RA+ GP E+ + G P PP
Sbjct: 11851 ATVLTPGTT-----VTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPP 11905
Query: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMD 1888
V + + + + D GK IT Y +E + W + K + +
Sbjct: 11906 EVTKVSKEEMTVVWNPPEYDGGKS-ITGYFLEKKEKHSTRWVPVNKSA---IPERRMKVQ 11961
Query: 1889 ILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1921
L P Y FRV A N+ G G PS PS+ V A+
Sbjct: 11962 NLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 11994
Score = 100 bits (248), Expect = 2e-20
Identities = 154/690 (22%), Positives = 263/690 (38%), Gaps = 56/690 (8%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRA- 134
+ +TSLD +R +N++G + + + E E S + ++RA
Sbjct: 12065 FTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAG 12124
Query: 135 ------PRIASFPQPQVTWFRDG--RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAV 186
+ P P+VTW + G + + LVI ++ D+G+Y + V
Sbjct: 12125 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLV 12184
Query: 187 NDKNGDNKTSQPITLTVENVGGPADPIAPTIII---------PPKNTSVVAGTSEVTLEC 237
N + + + + V + GP + + + PP+N T + +
Sbjct: 12185 NPAG---EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKR 12241
Query: 238 VANARPLIKLHIIWKKDGVLLSGGI--SDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPS 295
A+ + + KK ++ + +++ R+T N G + VL S
Sbjct: 12242 EADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP--- 12298
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPS--ITWYKDAAVVEVEK 353
LS +PP+ ++ E +T + +P G IT Y++ ++
Sbjct: 12299 ------LSEPDPPRKLEVTE--MTKNSATLAWLPPLRDGGAKIDGYITSYREEEQ-PADR 12349
Query: 354 LTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAG----EVQTSTYLAVTSIAPNITRGPL 409
T + D L ++GL F+ ARNA G Y A + P P
Sbjct: 12350 WTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPE 12409
Query: 410 DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
T+ G + + G P P W+KGE + + S L S L+I D
Sbjct: 12410 QITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS-HLAVHKADSSSILIIKDVTRKD 12468
Query: 470 AGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVT--I 527
+G Y+ A NS G D +VV +PP D S I S+ + + +
Sbjct: 12469 SGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNIT 12528
Query: 528 RYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG-NDSRSAHLRV 586
YI EK + G + + S + + G + R + G ++ ++ V
Sbjct: 12529 NYIVEKCDVSRGDWVTALASVTKT-SCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMV 12587
Query: 587 RQLPHA-PEHPV-ATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASV 643
Q P P P A ++ V + I + W +P DG SP+I Y++E E N+ V
Sbjct: 12588 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 12647
Query: 644 DPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS--LPEEPPTAPPQNVIASG 701
++T GLV Y FR+ A+N G SK TE V+ +P +PP P +
Sbjct: 12648 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDV--- 12704
Query: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYC 731
T ++ + W P + I+ GY + C
Sbjct: 12705 -TKSTVSLIWARPKHDGGSKII-GYFVEAC 12732
Score = 94.0 bits (232), Expect = 1e-18
Identities = 163/705 (23%), Positives = 268/705 (38%), Gaps = 83/705 (11%)
Query: 41 GNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHA-----------GFY 89
G L+C G + KW +EL + +Y ++S RTH G Y
Sbjct: 24050 GEAAQLSCQIVGRPLPDIKWYRFGKELIQ---SRKYKMSSDGRTHTLTVMTEEQEDEGVY 24106
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASF--PQPQVTW 147
CI N +G + + +++ + F G + +G + P P +TW
Sbjct: 24107 TCIATNEVGEV-ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTW 24165
Query: 148 FRDGRKIPPSSRIAITLENTLVILSTVAPD------AGRYYVQAVNDKNGDNKTSQPITL 201
F G+K+ +S IT+ENT V + AG+Y VQ N + L
Sbjct: 24166 FH-GQKLLQNSE-NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG-----TVDAIL 24218
Query: 202 TVENVGGPADPIAPTIIIPP-KNTSVVA-------GTSEVTLECVANARPLIKLHIIWKK 253
VE P P P +I KN++V++ G S +T V K W+
Sbjct: 24219 DVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEA--KEGAEWQ- 24275
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKE 313
L+S IS R+ N T +AGYY + + + + + + +++ P ++
Sbjct: 24276 ---LVSSAISVTTCRIV--NLT-ENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP--FEK 24327
Query: 314 PERHITAEMEKVVDIPCQAKGVPPPSI------TWYKDAAVVEVEKLTRF--RQRNDGGL 365
P + V C PP S +Y + + K + +
Sbjct: 24328 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 24387
Query: 366 QISGLVPDDTGMFQCFARNAAGEVQTSTYLA-------VTSIAPNITRGPLDSTVIDGMS 418
+ L+ F+ N GE + S V AP+ + V +
Sbjct: 24388 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 24447
Query: 419 VVLACETSGAPRPAITW-QKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTC 475
L C+ +G P+P + W ++G+ I+A G R + G L+I+ DA Y
Sbjct: 24448 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY--RIQEFKGGYHQLIIASVTDDDATVYQV 24505
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSV-----IKGTQASMVCGVTHDPRVTIRYI 530
ATN G +A L V +I P + + ++G S+ + P I
Sbjct: 24506 RATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVIT-- 24563
Query: 531 WEKDGATLGTESHPRIRLDRNGSLHI--SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
W+K + H ++ + R+ + + + D G Y + G D ++ L V
Sbjct: 24564 WQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVAD 24623
Query: 589 LPHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKA 647
+P P +S V R ++NLTWT+P DG S + YI+E A + + +
Sbjct: 24624 VPDPPRG--VKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RE 24679
Query: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 692
T TV L SYQFR+ A N G + S+ +E E+ A
Sbjct: 24680 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 24724
Score = 90.5 bits (223), Expect = 2e-17
Identities = 155/724 (21%), Positives = 278/724 (38%), Gaps = 106/724 (14%)
Query: 311 VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG---GLQI 367
+++ + +T ++ + + CQ G P P I WY+ E+ + +++ +DG L +
Sbjct: 24038 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGK--ELIQSRKYKMSSDGRTHTLTV 24095
Query: 368 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS- 426
+D G++ C A N GEV+TS+ L + + PL + L
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24155
Query: 427 -GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE 485
G P PA+TW G+++L + T + ++ + + AG Y +N G +
Sbjct: 24156 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVD 24215
Query: 486 ASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTI-RYIWEKDGATLGTESH 543
A D+ + + + T P ++++K + D I Y+ EK A G E
Sbjct: 24216 AILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE-- 24273
Query: 544 PRIRLDRNGSLHISQTWSGDIGTYTCRV------------ISAGGNDSRSAHLRVRQL-- 589
Q S I TCR+ +SA S L V +
Sbjct: 24274 -------------WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 24320
Query: 590 -------PHAPEHPVATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLA 641
P AP P T++ V + + + W P DG + + Y LE E + +
Sbjct: 24321 IKSPFEKPGAPGKP--TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVT 24378
Query: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP------Q 695
+ + + T +VK L+ Y+FR+ N G+ ++S+ +E ++ + P P +
Sbjct: 24379 TEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELR 24438
Query: 696 NVIASGRTNQSIMIQWQPPPESHQNGILKGYI---------IRYCLAGLPVGYQ---FKN 743
N+ ++N +++ + H I+K Y ++Y + GY +
Sbjct: 24439 NLNVRYQSNATLVCK----VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIAS 24494
Query: 744 ITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEAT 803
+TD D + TN V+ S + V + TL+G+ G VHA
Sbjct: 24495 VTDDDATVYQVRA----TNQGGSVSGTASLEVEVPAKIHLPKTLEGM-----GAVHALRG 24545
Query: 804 NSTTIRFTWNA-PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS--- 859
+I+ ++ P P +I W+ Q+ ++ ++Q + F S
Sbjct: 24546 EVVSIKIPFSGKPDP-----------VITWQKGQD----LIDNNGHYQVIVTRSFTSLVF 24590
Query: 860 --GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917
G+++ F V+C + T +L DVP P + S++ S+ ++W E
Sbjct: 24591 PNGVERKDAGF-YVVCAKNRFGIDQKTVEL--DVADVPDPPRGVKVSDVSRDSVNLTWTE 24647
Query: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976
P G +T Y + E+ T R Y V L T+Y V A G
Sbjct: 24648 PASDGGSKITNYIV--EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGL 24705
Query: 977 GQVS 980
+ S
Sbjct: 24706 SKPS 24709
Score = 85.5 bits (210), Expect = 5e-16
Identities = 101/393 (25%), Positives = 164/393 (41%), Gaps = 50/393 (12%)
Query: 139 SFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
S P V W +D +++ + RI I E + L+I ST DAG+Y V A G+ T
Sbjct: 3036 SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVST 3091
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDG 255
++ L VE I + + K +VV EV + V W KDG
Sbjct: 3092 AK---LFVEGRDVRIRSIKKEVQVIEKQRAVVE--FEVNEDDV---------DAHWYKDG 3137
Query: 256 VLLSGGISDHNR--------RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP 307
+ ++ + + ++ R+ I SDAG Y A SSV Y++ EP
Sbjct: 3138 IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT-----LYVNAPEP 3192
Query: 308 PQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRF-RQRNDGGLQ 366
PQ ++E + +T + K G P P I+WYK+ ++ +F + L
Sbjct: 3193 PQVLQELQP-VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT-----------SIAPNITRGPLDSTVI- 414
+ P+D ++ C A+N G TS L+V + P PL TV
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
+G C SG + K ++I S ++ +F ++ L I+ + D GTYT
Sbjct: 3312 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFE--DTYQLEIAEAYPEDEGTYT 3369
Query: 475 CLATNSRGVDEASADLVVWARTRITKPPQDQSV 507
+A+N+ G ++A+L + A I +Q +
Sbjct: 3370 FVASNAVGQVSSTANLSLEAPESILHERIEQEI 3402
Score = 83.6 bits (205), Expect = 2e-15
Identities = 113/486 (23%), Positives = 191/486 (39%), Gaps = 71/486 (14%)
Query: 120 KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAP 176
K +V+ GE A S+ V W+ G+K+ PS ++ E +TL +
Sbjct: 5706 KDVTVTAGETATFDCE--LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 5763
Query: 177 DAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
DAG + A + K N L V+ P P V + LE
Sbjct: 5764 DAGEVQLTAKDFKTHAN-------LFVKE--------PPVEFTKPLEDQTVEEGATAVLE 5808
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-----ISDHN-RRLTIPNPTGSDAGYYECEAVLRS 290
C + + W K+G + ++D R+L I + T D Y C+A
Sbjct: 5809 CEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK 5865
Query: 291 SSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVE 350
+S L+V+ P P + +++ C+ + W+KD A E
Sbjct: 5866 TS-------CNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVKWFKDGA--E 5915
Query: 351 VEKLTRFRQRNDGGLQI---SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRG 407
++K ++ + G ++I + + DD + C R A +TS L V T+
Sbjct: 5916 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLEEEAVFTKN 5971
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKG-ERILASGSVQLPRFTPLESGSLLISPTH 466
+ V + ++ L CE S P + W KG E I+ +G ++ T L+I H
Sbjct: 5972 LANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEI--LTEGRKRILVIQNAH 6028
Query: 467 ISDAGTYTCLATNSR-----GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
+ DAG Y C +SR V E +A+ + PQ+ +++G +A VC ++
Sbjct: 6029 LEDAGNYNCRLPSSRTDGKVKVHELAAEFI--------SKPQNLEILEGEKAEFVCSISK 6080
Query: 522 DPRVTIRYIWEKDGATLGT-ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSR 580
+ + W++D TL + + + I + L + D+GTY V G
Sbjct: 6081 E---SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARA 6133
Query: 581 SAHLRV 586
+AHL V
Sbjct: 6134 AAHLTV 6139
Score = 77.4 bits (189), Expect = 1e-13
Identities = 101/443 (22%), Positives = 159/443 (35%), Gaps = 77/443 (17%)
Query: 118 GEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTV 174
G K+ +V GE+ + I+ +P P VTW+R+ +I S IT ++ L+I
Sbjct: 902 GLKNVTVIEGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAF 960
Query: 175 APDAGRYYVQAVNDKNGDNKT-------------------------------SQPITLT- 202
A D+GR+ AVN+ + + S+ + +T
Sbjct: 961 AEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1020
Query: 203 ---VENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
E GP +P AP I P +V G S V C P K H+ WKK GV L+
Sbjct: 1021 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS-VVFGCQVGGNP--KPHVYWKKSGVPLT 1077
Query: 260 GGIS---DHNR-----RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQF- 310
G +N+ +L I DAG Y V+R+ + A S+LE +
Sbjct: 1078 TGYRYKVSYNKQTGECKLVISMTFADDAGEY--TIVVRNKHGET---SASASLLEEADYE 1132
Query: 311 -VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISG 369
+ + ++ + + + + G P + + E E+ ++ + +
Sbjct: 1133 LLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRT 1192
Query: 370 LVPDDTGMFQCFARNAAGEVQ---------------TSTYLAVTSIAPNITRGPLDS--- 411
V D F E++ +AV DS
Sbjct: 1193 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1252
Query: 412 --TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISD 469
+++GM V C+ SG P P I W K + + G F SL I D
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 470 AGTYTCLATNSRGVDEASADLVV 492
G YT A+N +G S L V
Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYV 1335
Score = 77.0 bits (188), Expect = 2e-13
Identities = 71/269 (26%), Positives = 105/269 (39%), Gaps = 58/269 (21%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-- 364
PP V + E E V + C G P P++TWY++ ++E F+ G
Sbjct: 896 PPTLVSGLKNVTVIEGESVT-LECHISGYPSPTVTWYRED--YQIESSIDFQITFQSGIA 952
Query: 365 -LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-------------------------- 397
L I +D+G F C A N AG V TS YLAV
Sbjct: 953 RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1012
Query: 398 --------TSI-----------APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKG 438
TS+ AP P+ +++G SVV C+ G P+P + W+K
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072
Query: 439 ERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWART 496
L +G + ++G L+IS T DAG YT + N G ASA L+ A
Sbjct: 1073 GVPLTTGYRYKVSYNK-QTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Query: 497 RITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ Q + + + + V +P+V
Sbjct: 1132 ELLMKSQQEMLYQ----TQVTAFVQEPKV 1156
Score = 69.3 bits (168), Expect = 4e-11
Identities = 134/549 (24%), Positives = 214/549 (38%), Gaps = 78/549 (14%)
Query: 897 PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRIS-WEEYNRTNTRVTHYLPNVTLEYR 954
P G + +L S +SW+ P + G +T Y + E ++ +VT R
Sbjct: 24229 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTT-CR 24287
Query: 955 VTGLTALTTYTIEVAAMTSKGQG---QVSASTISSGVPPELPGPPTNLGISNIGPRSVTL 1011
+ LT Y V+A + G +VS+ I P E PG P I+ + S +
Sbjct: 24288 IVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS-PFEKPGAPGKPTITAVTKDSCVV 24346
Query: 1012 QFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFR 1070
++P DG I + +E + + +W+ + + E V +L Y FR
Sbjct: 24347 AWKPPASDGGAKIRNYYLEKREK---KQNKWISV--TTEEIRETVFSVKNLIEGLEYEFR 24401
Query: 1071 MRQVNIVGTSPPSQPSRKIQTLQAPPDMAP------ANVSLRTASETSLWLRWM--PLPE 1122
++ N+ G S S+ S I P AP N+++R S +L + P P
Sbjct: 24402 VKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 24461
Query: 1123 ME-YNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAI 1181
++ Y E + +KY + G ++ + D T+ QV+A N
Sbjct: 24462 VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATV----------YQVRATNQG 24511
Query: 1182 GS--GPWSQTVVGRTRESVPSS--GPTNVSALATTSSSMLVRWSEVPEA----------- 1226
GS G S V + +P + G V AL S+ + +S P+
Sbjct: 24512 GSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLI 24571
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
D NG Y+V+ + LV N + G YV V A R G
Sbjct: 24572 DNNG---HYQVIVTRSFTS------LVFPNG---VERKDAGFYV-----VCAKNRFGIDQ 24614
Query: 1287 PSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346
+ +E + DVP PP G+ +V SV L W PA+ G +IT+ + A
Sbjct: 24615 KT----VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG----SKITNYIVEKCAT 24666
Query: 1347 TATVEVLAPSARQ--YTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPS 1404
TA + AR+ YT L ++ Y FR+ A+ + G + +E T K D+ +
Sbjct: 24667 TAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK----T 24722
Query: 1405 RPMVQQEDV 1413
R M E+V
Sbjct: 24723 RAMNYDEEV 24731
Score = 67.8 bits (164), Expect = 1e-10
Identities = 85/414 (20%), Positives = 173/414 (41%), Gaps = 46/414 (11%)
Query: 16 RAARAQDDVSPYFKTEPVRTQVHL-EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY 74
+ ++A ++V + + + TQ+ + EG RLVL G+ + KW+ N ELT S EY
Sbjct: 26530 KTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA--TDVKWVLNGVELTN-SEEY 26586
Query: 75 RYMITSLDRT---------HAGFYRCIVRNRMGALLQRQTEV----QVAYMGSFEEGEKH 121
RY ++ D+T G CI + + G +++ Q ++ +++ +F +
Sbjct: 26587 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEG-IVKCQYDLTLSKELSDAPAFISQPRS 26645
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDA 178
Q+++ G+ + I+ P P++ WF++ I SS ++I+ +L I + D+
Sbjct: 26646 QNINEGQNVLFTC-EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 26704
Query: 179 GRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECV 238
G+Y ++A N + + T+ + L + +P ++ +TS+ S +++
Sbjct: 26705 GKYTIKAKNFRGQCSATASLMVLPLVE-----EPSREVVLRTSGDTSLQGSFSSQSVQMS 26759
Query: 239 ANARPL-------IKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSS 291
A+ + + + +S + + + S G + S+
Sbjct: 26760 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESST 26819
Query: 292 S--VPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S + + +RG PP+ P I+ + KV+ + C G P P +TW +
Sbjct: 26820 SKMLKAGIRGI------PPKIEALPS-DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 26872
Query: 350 EVEKLTRFRQRNDGGLQ---ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI 400
++ RF N L I + D G++ N G + + + SI
Sbjct: 26873 HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 65.9 bits (159), Expect = 4e-10
Identities = 107/426 (25%), Positives = 171/426 (40%), Gaps = 45/426 (10%)
Query: 283 ECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEP-ERHITAEMEKVVDIPCQA--KGVPPPS 339
E EA + S P+ + LS+ +P P + H+T K + I + K P
Sbjct: 7764 ENEAGVGHPSEPTEI----LSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPI 7819
Query: 340 ITWYKDAAVVEVEKLTRFRQRNDGGLQIS---GLVPDDTGMFQCFARNAAG-----EVQT 391
I ++ + V EK R R L+ G+VPD + + A NA G E+
Sbjct: 7820 IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 7879
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLP 450
+ P I D VI+G + + P P ++W K G+ + AS + +
Sbjct: 7880 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 7939
Query: 451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKG 510
S L + + +DAG YT N G AS ++ V + P +D
Sbjct: 7940 N--DHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIG---LPGPCKDIKASDI 7994
Query: 511 TQASMVCGVTHDP------RVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDI 564
T++S C +T +P + Y+ E+ A G ++ + +G +S T I
Sbjct: 7995 TKSS--CKLTWEPPEFDGGTPILHYVLERREA--GRRTYIPVM---SGENKLSWTVKDLI 8047
Query: 565 --GTYTCRVISA----GGNDSRSAHLRVRQLPHAPEHPVATLSTVE--RRAINLTWTKP- 615
G Y RV + GG + + Q P P P + A+ +TW P
Sbjct: 8048 PNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPL 8107
Query: 616 FDGNSPLIRYILE-MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+DG S ++ YI+E +++ W + P T T KGL + YQFR+ A N G
Sbjct: 8108 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILT-YTAKGLEEGKEYQFRVRAENAAGIS 8166
Query: 675 QFSKDT 680
+ S+ T
Sbjct: 8167 EPSRAT 8172
Score = 65.9 bits (159), Expect = 4e-10
Identities = 75/363 (20%), Positives = 146/363 (40%), Gaps = 33/363 (9%)
Query: 251 WKKDGVLLSG------GISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSV 304
W +GV L+ G+S ++ LTI + D G C S + +V+ Y
Sbjct: 26573 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI----SKTKEGIVKCQYDLT 26628
Query: 305 L-----EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFR 358
L + P F+ +P E + V+ C+ G P P I W+K+ + + ++ R
Sbjct: 26629 LSKELSDAPAFISQPRSQNINEGQNVL-FTCEISGEPSPEIEWFKNNLPISISSNVSISR 26687
Query: 359 QRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPL----DSTVI 414
RN L+I D+G + A+N G+ + L V + +R + T +
Sbjct: 26688 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 26747
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
G + + S + + A ++ AS ++ +F + + S+ + + +
Sbjct: 26748 QGSFSSQSVQMSASKQEA-SFSSFSSSSASSMTEM-KFASMSAQSMSSMQESFVEMSSSS 26805
Query: 475 CLATNSRGVDEASADLVVWARTRITKP-----PQDQSVIKGTQASMVCGVTHDPRVTIRY 529
+ ++ E+S ++ A R P P D S+ +G ++ C T +P T
Sbjct: 26806 FMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEP--TPEV 26863
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 586
W G + ++ R ++ +L I D G YT + + G+DS + ++ +
Sbjct: 26864 TWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Query: 587 RQL 589
R +
Sbjct: 26924 RSI 26926
Score = 64.7 bits (156), Expect = 9e-10
Identities = 118/468 (25%), Positives = 185/468 (39%), Gaps = 61/468 (13%)
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLEN----TLVILSTVAPD 177
Q+V G A R R+ P P+ W+++G KI S RI LVI A D
Sbjct: 2041 QTVGQGSDAHFRV-RVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAED 2099
Query: 178 AGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSE--VTL 235
+ V+A+N +TS L V+ I + VVA + T
Sbjct: 2100 SASIMVKAINIA---GETSSHAFLLVQ--------AKQLITFTQELQDVVAKEKDTMATF 2148
Query: 236 ECVANARPLIKLHIIWKKDGVLLSGG--ISDHNRR----LTIPNPTGSDAGYYECEAVLR 289
EC + P +K + W KDG+ + G H+ R L+I SDA Y C V
Sbjct: 2149 EC-ETSEPFVK--VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2205
Query: 290 ---SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY-KD 345
++ +V GA + ++ Q ++ PE + + E+E +V P +G WY D
Sbjct: 2206 ENVKTTAKLIVEGAVVEFVKELQDIEVPESY-SGELECIVS-PENIEG------KWYHND 2257
Query: 346 AAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
+ K T +R L + + +D G + +T+ L + I
Sbjct: 2258 VELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKLKMKPRPIAIL 2313
Query: 406 RGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPT 465
+G D V +G V L + S + + G+ + S V + +S LLI
Sbjct: 2314 QGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI--VIDKQSHMLLIEDM 2371
Query: 466 HISDAGTYTC------LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGV 519
DAG Y+ L+T+ R V S D++ P +D +VI+GT+A + C V
Sbjct: 2372 TKEDAGNYSFTIPALGLSTSGR-VSVYSVDVIT--------PLKDVNVIEGTKAVLECKV 2422
Query: 520 THDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
+ P VT + D + I L I++T + D G Y
Sbjct: 2423 S-VPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2469
Score = 64.7 bits (156), Expect = 9e-10
Identities = 89/345 (25%), Positives = 132/345 (38%), Gaps = 38/345 (11%)
Query: 268 RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVD 327
RL IP+ SDAG Y A S+ V G + + + +K+ E + + VV+
Sbjct: 3067 RLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRI----RSIKK-EVQVIEKQRAVVE 3121
Query: 328 IPCQAKGVPPPSITWYKDAAVVEVEKLTRFR---QRNDGGLQISGLVPDDTGMFQCFARN 384
V WYKD + + R + +R + IS D G +
Sbjct: 3122 FEVNEDDV---DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF---- 3174
Query: 385 AAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLACETSGAPRPAITWQKGERILA 443
AG ++S L V + P L TV G SG P+P I+W K E++L+
Sbjct: 3175 VAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLS 3234
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA--------- 494
+G + + +LL+ DA YTC A N GV SA L V
Sbjct: 3235 TG-FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Query: 495 ----RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIW-EKDGATLGTESHPRIRLD 549
I P QD +G A C V+ ++ W KD + + +
Sbjct: 3294 MPVYPPAIITPLQDTVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 550 RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE 594
L I++ + D GTYT +A G S +A+L + APE
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL----EAPE 3391
Score = 64.3 bits (155), Expect = 1e-09
Identities = 103/471 (21%), Positives = 164/471 (34%), Gaps = 106/471 (22%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQ 197
P P VTW R G+ + S+R +T ++T I S A D G Y V +N + K
Sbjct: 26091 PVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVV---ENSEGKQEA 26147
Query: 198 PITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVL 257
TLT++ A + PP+ V + P +K K
Sbjct: 26148 EFTLTIQK----ARVTEKAVTSPPR---------------VKSPEPRVKSPEAVKSP--- 26185
Query: 258 LSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA-YLSVLEPPQFVKEPER 316
+R+ P P+ +AV + + P+ +L V PP+ + +
Sbjct: 26186 ---------KRVKSPEPSHP-------KAVSPTETKPTPTEKVQHLPVSAPPKITQFLKA 26229
Query: 317 HITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQISGLVPDD 374
+ E+ K+ + ++ + +TWYKD ++ +F DG L+I+ L D
Sbjct: 26230 EASKEIAKLTCV-VESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESD 26288
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G + CE SG
Sbjct: 26289 QGEY-------------------------------------------VCEISG------- 26298
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 494
+G + F + IS T SD T T E A + +
Sbjct: 26299 --EGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT---EPKAPEPISS 26353
Query: 495 RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS- 553
+ I QD +V + A T +PR T IW KDG + ++ D+ G
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTA--IWTKDGKAITQGGKYKLSEDKGGFF 26411
Query: 554 LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVE 604
L I +T + D G YTC V ++ G+ S S L ++ + V+T T E
Sbjct: 26412 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 26462
Score = 62.4 bits (150), Expect = 5e-09
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 8/165 (4%)
Query: 334 GVPPPSITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQ 390
G P P ++W++D V+ L + G L I + ++G + A N +G+
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQAT 90
Query: 391 TSTYLAVTS--IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSV 447
++ L V + PN + TV G V L +G P P + + + G I +S
Sbjct: 91 STAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDF 150
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
Q+ + L S LLI+ + D+GTY+ ATNS G ++A+L+V
Sbjct: 151 QISQEGDLYS--LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 62.0 bits (149), Expect = 6e-09
Identities = 51/212 (24%), Positives = 104/212 (49%), Gaps = 13/212 (6%)
Query: 397 VTSIAPNITRGPLDSTVI-DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPL 455
+T+ AP T+ PL S V+ +G + SG P P ++W + +++++ ++ + +
Sbjct: 1 MTTQAPTFTQ-PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS 59
Query: 456 ESGSLLISPTHI-SDAGTYTCLATNSRGVDEASADLVVWART---RITKPPQDQSVIKGT 511
+ + L P +++G Y+ ATN G ++A+L+V A T + Q +V +G+
Sbjct: 60 DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGS 119
Query: 512 QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH---ISQTWSGDIGTYT 568
Q + VT P +++ +DGA + +S ++ + G L+ I++ + D GTY+
Sbjct: 120 QVRLQVRVTGIPTPVVKFY--RDGAEI--QSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 569 CRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
++ G + +A L V+ P T+
Sbjct: 176 VNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Score = 62.0 bits (149), Expect = 6e-09
Identities = 50/193 (25%), Positives = 85/193 (44%), Gaps = 13/193 (6%)
Query: 214 APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG--------ISDH 265
APT P ++ V+ G S T E + P+ + + W +DG ++S SD
Sbjct: 5 APTFTQPLQSVVVLEG-STATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDG 61
Query: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
+LTIP T +++G Y +A S S + PP FV+ + +T
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-SMTVRQGSQ 120
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND-GGLQISGLVPDDTGMFQCFARN 384
V + + G+P P + +Y+D A ++ + Q D L I+ P+D+G + A N
Sbjct: 121 VRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 385 AAGEVQTSTYLAV 397
+ G ++ L V
Sbjct: 181 SVGRATSTAELLV 193
Score = 61.6 bits (148), Expect = 8e-09
Identities = 73/294 (24%), Positives = 108/294 (36%), Gaps = 64/294 (21%)
Query: 343 YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA- 401
YK A VEV+K + G+ I+G + F+ A +T+ A I
Sbjct: 844 YKSEAGVEVKK--------EVGVSITGTTVREE-RFEVLHGREAKVTETARVPAPVEIPV 894
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P + G + TVI+G SV L C SG P P +TW + + + S S+
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIES-SIDFQITFQSGIAR 953
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADL----------------------------- 490
L+I D+G +TC A N G S L
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013
Query: 491 --VVWARTRITK---------------PPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
VV T +T+ P Q +++G C V +P+ + W+K
Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV--YWKK 1071
Query: 534 DGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
G L T ++ ++ L IS T++ D G YT V + G S SA L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 58.9 bits (141), Expect = 5e-08
Identities = 73/277 (26%), Positives = 111/277 (40%), Gaps = 21/277 (7%)
Query: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSI--TWYKDAAVVEVEKLTRF-RQRNDG 363
P +FVKE + I E E V V P + TW KD + + RF D
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 4676
Query: 364 GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDGMSVVLA 422
L I + D G + C R E ++ L V + + + TV+ G + L+
Sbjct: 4677 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLS 4736
Query: 423 CETSGAPRPAITWQKGERILASGSVQLP-RFTPLESG---SLLISPTHISDAGTYTCLAT 478
CE + + W+K +I+ V+ P R P G +L I+ +DAGTYT
Sbjct: 4737 CELN--KERDVVWRKDGKIV----VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 4790
Query: 479 NSRGVDEASADLVVWA-RTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 537
N+ ++ +S VV R + KP +DQ V A C + D T W K
Sbjct: 4791 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKD---TPNIKWFKGYDE 4847
Query: 538 LGTESHPRIRLDRNGS---LHISQTWSGDIGTYTCRV 571
+ E + + + R+G+ L I DI Y +
Sbjct: 4848 IPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 4884
Score = 58.5 bits (140), Expect = 7e-08
Identities = 119/615 (19%), Positives = 209/615 (33%), Gaps = 95/615 (15%)
Query: 22 DDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSL 81
+ +PYF T+PV Q +EG +V C G+ W + LT YRY ++
Sbjct: 1032 EPAAPYFITKPV-VQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTT---GYRYKVSYN 1087
Query: 82 DRT-------------HAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGE 128
+T AG Y +VRN+ G + ++ A + ++
Sbjct: 1088 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQV 1147
Query: 129 AAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVND 188
A ++ P++ V + + I + V++ T D +++ + +
Sbjct: 1148 TAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQ-EFHISSFEE 1206
Query: 189 KNGDNKTSQPITLTVENVG------------GPADPIAPTIIIPPKNTSVVAGTSEVTLE 236
+ + I T+E + ++ + KN ++ G VT
Sbjct: 1207 RLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMG-VTFH 1265
Query: 237 CVANARPLIKLHIIWKKDGVLLSGG-------ISDHNRRLTIPNPTGSDAGYYECEAVLR 289
C + PL K I W KDG + G + D L IP D G Y A
Sbjct: 1266 CKMSGYPLPK--IAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA--- 1320
Query: 290 SSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVV 349
S ++G + C K P+ +
Sbjct: 1321 -----SNIKGNAI---------------------------CSGKLYVEPAAPLGAPTYIP 1348
Query: 350 EVEKLTRFRQRNDGGLQISGLVPDDTGMFQCF---ARNAAGEVQTSTYLAVTSIA----- 401
+E ++R R + + S + M AR + + L T +
Sbjct: 1349 TLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERL 1408
Query: 402 --PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGS 459
P P+ ++G + + G P P W + + + + S
Sbjct: 1409 YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQS 1468
Query: 460 LLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPP-----QDQSVIKGTQAS 514
L+I P SD+G +T +A N G S L V A KP ++ ++ +G++
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1528
Query: 515 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD---RNGSLHISQTWSGDIGTYTCRV 571
M T +P I +W K+ + +P+IR++ +L I T S D YT
Sbjct: 1529 MKVRATGNPNPDI--VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1586
Query: 572 ISAGGNDSRSAHLRV 586
I+ G D+ + V
Sbjct: 1587 INKAGRDTTRCKVNV 1601
Score = 58.5 bits (140), Expect = 7e-08
Identities = 63/252 (25%), Positives = 95/252 (37%), Gaps = 21/252 (8%)
Query: 262 ISDHNRRLTIPNPTGSDAGYYEC---------EAVLRSSSVPSVVRGAYLSVLEPPQFVK 312
+ D R + N G D+ Y E + R + R + +LE P
Sbjct: 25137 LDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFT 25196
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRNDGGLQ---IS 368
P + TA + + V P P +TWYK ++ + ++ +D GL I+
Sbjct: 25197 LPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTIN 25256
Query: 369 GLVPDDTGMFQCFARNAAGEVQTSTYLAVT--------SIAPNITRGPLDSTVIDGMSVV 420
+ DD + ARN GE L VT ++ P R ++ +G SV
Sbjct: 25257 SVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVC 25316
Query: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
SG P P + W+K + L+ G L+ +L I T D G Y ATN+
Sbjct: 25317 FEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT 25376
Query: 481 RGVDEASADLVV 492
G A L V
Sbjct: 25377 AGSTSCQAHLQV 25388
Score = 57.8 bits (138), Expect = 1e-07
Identities = 84/361 (23%), Positives = 124/361 (34%), Gaps = 62/361 (17%)
Query: 279 AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPP 338
A C +RS SV + S+ P V H E V C+ +
Sbjct: 25043 AARISCGGAIRSQKGVSVAKVKVASIEIGP--VSGQIMHAVGEEGGHVKYVCKIENYDQS 25100
Query: 339 S-ITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTY 394
+ +TWY V ++E ++ + G L + + D G ++C N GE +
Sbjct: 25101 TQVTWY--FGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAE 25158
Query: 395 LAVTSIA---------------------------PNITRGPLDSTVIDGMSVVLACETSG 427
L V + P T + T G +V +
Sbjct: 25159 LFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITV 25218
Query: 428 APRPAITWQKGERILASGSVQLPRFTPLESG--SLLISPTHISDAGTYTCLATNSRGVDE 485
P P +TW K + + G + G L I+ D YT +A N G D
Sbjct: 25219 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS 25278
Query: 486 ASADLVVWARTRITKPPQDQSV---IKGTQASMVCG----------VTHDPRVTIRYIWE 532
A L V + PP D ++ K A+ C V+ P T++ WE
Sbjct: 25279 CKAKLTV----TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WE 25332
Query: 533 KDGATLGTESHPRIRLDRNG----SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ 588
KDG L P I + G +LHI T D G Y + G+ S AHL+V +
Sbjct: 25333 KDGQPLSLG--PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVER 25390
Query: 589 L 589
L
Sbjct: 25391 L 25391
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Query: 388 EVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSV 447
E +++T T++A I P TV +G S +C+T G P P +TW + ++L++ +
Sbjct: 26050 EEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSAR 26109
Query: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW----ARTRITKPPQ 503
T +S + IS SD G Y+ + NS G EA L + +T PP+
Sbjct: 26110 HQVTTTKYKS-TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPR 26168
Query: 504 DQS 506
+S
Sbjct: 26169 VKS 26171
Score = 57.4 bits (137), Expect = 2e-07
Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 26/210 (12%)
Query: 308 PQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFR-QRNDGGLQ 366
P F+KE + M V + G+P P I W+ + ++ +F +D L
Sbjct: 3457 PIFIKEVS-NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLI 3515
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS-------------IAPNITR--GPLDS 411
I +D G + C A N G+ S YL + S +A ++ + GP
Sbjct: 3516 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3575
Query: 412 TVI---------DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLI 462
+ G+ + G P P +TW K + L + P SG+ ++
Sbjct: 3576 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 3635
Query: 463 SPTHISDAGTYTCLATNSRGVDEASADLVV 492
+ D+G Y C A N G +A+L+V
Sbjct: 3636 NDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 55.8 bits (133), Expect = 4e-07
Identities = 90/391 (23%), Positives = 145/391 (37%), Gaps = 54/391 (13%)
Query: 56 LEFKWLHNN--RELTKF--SLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY 111
L+ WL R TK +L++R +L + R G ++ Q V VA
Sbjct: 25003 LQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAK 25062
Query: 112 M--GSFEEGEKHQSVSH--GEAA--VIRAPRIASFPQP-QVTWFRDGRKIPPSSRIAITL 164
+ S E G + H GE V +I ++ Q QVTW+ R++ S + IT
Sbjct: 25063 VKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25122
Query: 165 ENTLVIL---STVAPDAGRYYVQAVNDKNGDNKTSQPIT------------LTVENVGGP 209
E+ + IL D G Y + VND D+ ++ T++ +
Sbjct: 25123 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25182
Query: 210 ADPI-----APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISD 264
D + P +P N + G V P + H+ W K G + G +D
Sbjct: 25183 TDTMRLLERPPEFTLPLYNKTAYVG-ENVRFGVTITVHP--EPHVTWYKSGQKIKPGDND 25239
Query: 265 HN---------RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP---QFVK 312
+LTI + T D Y V R+ + L PP ++
Sbjct: 25240 KKYTFESDKGLYQLTINSVTTDDDAEY--TVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25297
Query: 313 EPERHITAEME----KVVDIPCQAKGVPPPSITWYKDAAVVEV-EKLTRFRQRND-GGLQ 366
+ + A E + V + G+PPP++ W KD + + + + D L
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 397
I +P+DTG ++ A N AG +L V
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 55.5 bits (132), Expect = 6e-07
Identities = 62/224 (27%), Positives = 93/224 (41%), Gaps = 25/224 (11%)
Query: 1721 QAAPSAPSS-VKFSELTTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVS-KIVTVD 1777
Q P P+ + L S +SW+ P G + Y V E C +G ++V+
Sbjct: 24223 QDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNY--VVEKCEAKEGAEWQLVSSA 24280
Query: 1778 VKGNSPLWLKVKDLAEGVTYRFRIRAK-TFTYGPEIEAN---VTTGPGE--GAPGPPGVP 1831
+ S ++ +L E Y FR+ A+ TF +E + + P E GAPG P +
Sbjct: 24281 I---SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24337
Query: 1832 IIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILK 1891
+ + S +A + D G I Y +E R + W I +E+ FS+ L
Sbjct: 24338 AVTKDSCVVAWKPPASDGG-AKIRNYYLEKREKKQNKW---ISVTTEEIRETVFSVKNLI 24393
Query: 1892 PGVSYDFRVIAVNDYG------FGTPSSPSQSVPAQKANPFYEE 1929
G+ Y+FRV N G P +P VP Q A F EE
Sbjct: 24394 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ-APHFKEE 24436
Score = 55.1 bits (131), Expect = 7e-07
Identities = 128/600 (21%), Positives = 208/600 (34%), Gaps = 102/600 (17%)
Query: 23 DVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---KFSLEYRYM-- 77
+ PYF T + + +E + + L C P+ KW + E+ K+S++ +
Sbjct: 5163 EADPYF-TVKLHDKTAVEKDEITLKCEVSKDVPV--KWFKDGEEIVPSPKYSIKADGLRR 5219
Query: 78 ---ITSLDRTHAGFYRCIV---RNRMGALLQRQ----------TEVQVAYMGSFEEGEKH 121
I D G Y C + + ++ + EV V FE
Sbjct: 5220 ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSE 5279
Query: 122 QSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRY 181
V HG+ + P AS P DG+K + L++ + G
Sbjct: 5280 PDV-HGQWKLKGQPLTAS---PDCEIIEDGKK------------HILILHNCQLGMTGEV 5323
Query: 182 YVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANA 241
QA N K+ N L V+ + P I I P + V E EC +
Sbjct: 5324 SFQAANAKSAAN-------LKVKEL--------PLIFITPLSDVKVFEKDEAKFECEVSR 5368
Query: 242 RPLIKLHIIWKKDGVLLSGG-----ISDHNRR-LTIPNPTGSDAGYYECEAVLRSSSVPS 295
P W K ++G I D + + I + D Y EA + +S
Sbjct: 5369 EPKT---FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKL 5425
Query: 296 VVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKL 354
++ G L L P + V E+ V + + + W+K D + +
Sbjct: 5426 IIEGIRLKFLTPLKDVTAKEKE-----SAVFTVELSHDNI---RVKWFKNDQRLHTTRSV 5477
Query: 355 TRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI 414
+ + + L DDT + A + E + L V P T D T +
Sbjct: 5478 SMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAK----LTVLEGDPYFTGKLQDYTGV 5533
Query: 415 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 474
+ V+L CE S A P ++ G+ I S + + + L++ SD G YT
Sbjct: 5534 EKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIK--ADGKKRMLILKKALKSDIGQYT 5591
Query: 475 CLATNSRGVDEASADLVVWAR-TRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEK 533
C G D+ S L + R ++ +P V++ A ++ D I W+
Sbjct: 5592 C----DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISED---DIHANWKL 5644
Query: 534 DGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG------NDSRSAHLRVR 587
G L P + G +H + + CR+ GG N SAHLRV+
Sbjct: 5645 KGEAL--LQTPDCEIKEEGKIH-------SLVLHNCRLDQTGGVDFQAANVKSSAHLRVK 5695
Score = 54.7 bits (130), Expect = 1e-06
Identities = 91/439 (20%), Positives = 152/439 (34%), Gaps = 53/439 (12%)
Query: 92 IVRNRMGALLQRQTEVQVAY--------MGSFEEGEKHQSVSHGEAAVIRAPRIASFPQP 143
I++ + LL+ E ++A F+ K+ + G +++ +P P
Sbjct: 1216 IIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHC-KMSGYPLP 1274
Query: 144 QVTWFRDGRKIPPSSRIAITL----ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPI 199
++ W++DG++I R + +L I + D G Y A N K + +
Sbjct: 1275 KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK-- 1332
Query: 200 TLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS 259
L VE PA P+ IP TLE V+ R L + + + +S
Sbjct: 1333 -LYVE----PAAPLGAPTYIP-------------TLEPVSRIRSLSPRSV--SRSPIRMS 1372
Query: 260 GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHIT 319
R +P L + + R L P FV +P
Sbjct: 1373 PARMSPARM----SPARMSPARMSPGRRLEETDESQLER------LYKPVFVLKPVSFKC 1422
Query: 320 AEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGLVPDDTGM 377
E + + G P P W+ D + + + + DG L I P D+G
Sbjct: 1423 LEGQ-TARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGE 1481
Query: 378 FQCFARNAAGEVQTSTYLAVTSIA----PNITRGPLDSTVIDGMSVVLACETSGAPRPAI 433
+ A+N AG S L V ++ P + + +G + + +G P P I
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 434 TWQKGERILASGSVQLPRFTPLES-GSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
W K I+ R + +L I T D+ YT A N G D + V
Sbjct: 1542 VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Query: 493 WARTRITKPPQDQSVIKGT 511
+P + + +GT
Sbjct: 1602 EVEFAEPEPERKLIIPRGT 1620
Score = 53.9 bits (128), Expect = 2e-06
Identities = 103/491 (20%), Positives = 176/491 (35%), Gaps = 82/491 (16%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAIT---LENTLVILSTVAPDAGRYYVQAVNDKNGDN 193
I+ PQP+++W+++ + + + E TL+++ DA Y +A ND G
Sbjct: 3216 ISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKND-YGVA 3274
Query: 194 KTSQPITLTVENVGGPAD--PIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIW 251
TS +++ V V P P+ P II P +V + +C + L + W
Sbjct: 3275 TTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG---TDLKVSW 3331
Query: 252 -KKDGVLLSGGI-----SDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVL 305
KD + + +L I D G Y + S++V V A LS+
Sbjct: 3332 YSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY---TFVASNAVGQVSSTANLSLE 3388
Query: 306 EPPQFVKEP-ERHITAEMEKVVD--IPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND 362
P + E E+ I EM++ + + +G+ + K +E+
Sbjct: 3389 APESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLEL----------- 3437
Query: 363 GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLA 422
L S + P T P + ++ + G L+
Sbjct: 3438 --LSESPVYP------------------TKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3477
Query: 423 CETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRG 482
G P+P I W +L + S + SL+I T + D G YTC+A+N G
Sbjct: 3478 VTVIGIPKPKIQW-FFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYG 3536
Query: 483 VDEASADLVVWARTRITKPPQDQSVI-------------------------KGTQASMVC 517
SA L + ++ K + +S + +G A
Sbjct: 3537 KTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEY 3596
Query: 518 GVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS--LHISQTWSGDIGTYTCRVISAG 575
V +P T+ W K+ L T + I + NGS ++ D G Y C+ +
Sbjct: 3597 TVVGEPAPTV--TWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 3654
Query: 576 GNDSRSAHLRV 586
G + +A L V
Sbjct: 3655 GESTCAAELLV 3665
Score = 53.5 bits (127), Expect = 2e-06
Identities = 85/398 (21%), Positives = 146/398 (36%), Gaps = 47/398 (11%)
Query: 221 PKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG-----ISDHNRRLTIPNPT 275
P V + ECV + ++IW K ++ I+D + + + N +
Sbjct: 4994 PLKDVTVPERRQARFECVLTR----EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 5049
Query: 276 G-SDAGYYECEAVLRSSSVPSVVRGAYLSVLEP--PQFVKEPERHITAEMEKVVDIPCQA 332
D G Y E + +S V G L + P Q VKE E C+
Sbjct: 5050 QFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGE---------TATFVCEL 5100
Query: 333 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG-LQISGLVPDDTGMFQCFARNAAGEVQT 391
+ W+K+ A + + L++ + DD + + E+ +
Sbjct: 5101 SH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----ELSS 5155
Query: 392 STYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPR 451
+ L V P T D T ++ + L CE S P ++ GE I+ S P+
Sbjct: 5156 TAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVKWFKDGEEIVPS-----PK 5209
Query: 452 FTPLESG---SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR-TRITKPPQDQSV 507
++ G L I + D G Y C G D+ A++ V AR ++ KP V
Sbjct: 5210 YSIKADGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARLIKVEKPLYGVEV 5265
Query: 508 IKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTY 567
G A ++ + W+ G L + P + +G HI + +G
Sbjct: 5266 FVGETAHFEIELSEP---DVHGQWKLKGQPL--TASPDCEIIEDGKKHILILHNCQLG-M 5319
Query: 568 TCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVER 605
T V N +A+L+V++LP P++ + E+
Sbjct: 5320 TGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEK 5357
Score = 53.1 bits (126), Expect = 3e-06
Identities = 97/442 (21%), Positives = 163/442 (36%), Gaps = 51/442 (11%)
Query: 145 VTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITL 201
V WF+DG++I PS I + L++ + D G+Y G +KTS + +
Sbjct: 5551 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC-----GTDKTSGKLDI 5605
Query: 202 TVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLL--- 258
+ + P + T +E++ + +H WK G L
Sbjct: 5606 EDREI----KLVRPLHSVEVMETETARFETEISED---------DIHANWKLKGEALLQT 5652
Query: 259 -SGGISDHNR--RLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPE 315
I + + L + N G + +A SS V+ + +L P + V
Sbjct: 5653 PDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT--- 5709
Query: 316 RHITAEMEKVVDIPCQAKGVPPPSITWY-KDAAVVEVEKLTRFRQRNDGGLQISGLVPDD 374
+TA D + +P + WY K + +K+ + L + + +D
Sbjct: 5710 --VTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 5764
Query: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAIT 434
G Q A+ + +T L V T+ D TV +G + VL CE S
Sbjct: 5765 AGEVQLTAK----DFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKW 5820
Query: 435 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADL-VVW 493
++ G IL S ++ + L+I D TYTC A + + S +L VV
Sbjct: 5821 FKNGTEILKSKKYEIVADGRVR--KLVIHDCTPEDIKTYTCDAKDFK----TSCNLNVVP 5874
Query: 494 ARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT-ESHPRIRLDRNG 552
+P D V + A C ++ R + W KDGA + + + I
Sbjct: 5875 PHVEFLRPLTDLQVREKEMARFECELS---RENAKVKWFKDGAEIKKGKKYDIISKGAVR 5931
Query: 553 SLHISQTWSGDIGTYTCRVISA 574
L I++ D Y+C V +A
Sbjct: 5932 ILVINKCLLDDEAEYSCEVRTA 5953
Score = 50.8 bits (120), Expect = 1e-05
Identities = 68/294 (23%), Positives = 106/294 (36%), Gaps = 43/294 (14%)
Query: 326 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTR--FRQRNDGGLQISGLVPDDTGMFQCFAR 383
V C+ G P P I WYKD ++ + + F Q L+I ++P+D G++ FA
Sbjct: 1262 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1321
Query: 384 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 443
N G S L V AP GAP T + RI +
Sbjct: 1322 NIKGNAICSGKLYVEPAAP-----------------------LGAPTYIPTLEPVSRIRS 1358
Query: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP-- 501
+ R +P+ +SP +S A + R ++E + R+ KP
Sbjct: 1359 LSPRSVSR-SPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQL----ERLYKPVF 1413
Query: 502 ---PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG--SLHI 556
P ++G A V P W DG + + ++ + +G SL I
Sbjct: 1414 VLKPVSFKCLEGQTARFDLKVVGRPMP--ETFWFHDGQQIVNDYTHKVVIKEDGTQSLII 1471
Query: 557 SQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINL 610
D G +T + G S S L V A EH V + + + +N+
Sbjct: 1472 VPATPSDSGEWTVVAQNRAGRSSISVILTV----EAVEHQVKPMFVEKLKNVNI 1521
Score = 50.4 bits (119), Expect = 2e-05
Identities = 104/471 (22%), Positives = 175/471 (37%), Gaps = 66/471 (14%)
Query: 113 GSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLV 169
G+ + Q+V+ + AV + P + W RDG+ +P ++ I + L+
Sbjct: 2574 GAISKPLTDQTVAESQEAVFECE--VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLI 2631
Query: 170 ILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAG 229
I +T D G Y + K L VE V I T+ KN +V
Sbjct: 2632 IAATKLDDIGEYTYKVATSKTS-------AKLKVEAV-----KIKKTL----KNLTVT-- 2673
Query: 230 TSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLR 289
++ + V P +K + W K+GV+L + N + I S G +
Sbjct: 2674 ETQDAVFTVELTHPNVK-GVQWIKNGVVL-----ESNEKYAI-----SVKGTIYSLRIKN 2722
Query: 290 SSSVPSVVRGAYLSVL--------EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSIT 341
+ V V G L L E + +K+P + +TA V P
Sbjct: 2723 CAIVDESVYGFRLGRLGASARLHVETVKIIKKP-KDVTALENATVAFEVSVSHDTVPVKW 2781
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
++K + +K +R L + + P D G + G+++ L V ++
Sbjct: 2782 FHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTA----VVGQLECKAKLFVETL- 2836
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+IT+ + V + + CE S P++ + G I S ++ L L+
Sbjct: 2837 -HITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLH--QLI 2893
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
I T D+ YT + N D+ SA L V P S++K A +T
Sbjct: 2894 IMNTSTEDSAEYTFVCGN----DQVSATLTV-------TPIMITSMLKDINAEEKDTITF 2942
Query: 522 DPRVT---IRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYT 568
+ V I Y W K+G + + ++R + SL+I GD YT
Sbjct: 2943 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYT 2993
Score = 50.1 bits (118), Expect = 2e-05
Identities = 48/156 (30%), Positives = 63/156 (40%), Gaps = 4/156 (2%)
Query: 340 ITWY-KDAAVVEVEKLTRFRQRNDGGLQISGLVPDD-TGMFQCFARNAAGEVQTSTYLAV 397
+ WY ++ V EK + +N L I + +D G + C A N +G+ TS L V
Sbjct: 4272 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331
Query: 398 TS-IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLE 456
AP I R V G CE AP W K R + R +
Sbjct: 4332 VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4391
Query: 457 SGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
S SL I T + D G YTC A+N G +A L V
Sbjct: 4392 S-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/350 (24%), Positives = 134/350 (38%), Gaps = 39/350 (11%)
Query: 232 EVTLEC-VANARPLIKLHIIWKKDGVLLSGG------ISDHNRRLTIPNPTGSDAGYYEC 284
EV L+C ++ A +K W KDG + R L + SD G Y C
Sbjct: 5537 EVILQCEISKADAPVK----WFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC 5592
Query: 285 EAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV---DIPCQAKGVPPPSIT 341
+ +S + + ++ P V+ E TA E + DI K
Sbjct: 5593 DCGTDKTSGKLDIEDREIKLVRPLHSVEVMETE-TARFETEISEDDIHANWK-------- 5643
Query: 342 WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA 401
K A+++ + L + D TG A N V++S +L V
Sbjct: 5644 -LKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAAN----VKSSAHLRVKPRV 5698
Query: 402 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLL 461
+ R D TV G + CE S P + KG+++ S V +PR + + +L
Sbjct: 5699 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKV-VPR-SEGKVHTLT 5756
Query: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVV-WARTRITKPPQDQSVIKGTQASMVCGVT 520
+ + DAG A + + A+L V TKP +DQ+V +G A + C V+
Sbjct: 5757 LRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS 5812
Query: 521 HDPRVTIRYIWEKDGA-TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTC 569
R + W K+G L ++ + + R L I DI TYTC
Sbjct: 5813 ---RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5859
Score = 48.1 bits (113), Expect = 9e-05
Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 1850 GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFG 1909
G +T Y++E R +D W + EV +F + L PG Y FRV AVN+YG G
Sbjct: 12229 GGSQVTHYIVEKREADRKTWST----VTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPG 12284
Query: 1910 TPSSPSQSVPA 1920
P+ + V A
Sbjct: 12285 VPTDVPKPVLA 12295
Score = 47.8 bits (112), Expect = 1e-04
Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 1364 GLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW- 1422
G++ + + + A+ R G + L V D P PP V+ DV SV L+W
Sbjct: 24593 GVERKDAGFYVVCAKNRFGIDQKTVELDVA----DVPDPPRG--VKVSDVSRDSVNLTWT 24646
Query: 1423 EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDI 1482
EP SDG S + Y ++ + RW + + + V L TSY+FRV A N
Sbjct: 24647 EPASDGGSKITNYIVEKCATTAERWLRVGQA---RETRYTVINLFGKTSYQFRVIAENKF 24703
Query: 1483 GDSEFSEESESLTT 1496
G S+ SE SE T
Sbjct: 24704 GLSKPSEPSEPTIT 24717
Score = 47.0 bits (110), Expect = 2e-04
Identities = 66/318 (20%), Positives = 120/318 (37%), Gaps = 55/318 (17%)
Query: 30 TEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSL----------EYRYMIT 79
T+P+++ V LEG+ G E W + + ++ +L + I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 80 SLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAP-RIA 138
++ + ++G Y N G + A ++ QS++ + + +R R+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 139 SFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDNKT 195
P P V ++RDG +I S I+ E +L+I D+G Y V A N T
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATST 188
Query: 196 SQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVT----------LECVANARPLI 245
++ + E V P K T + T++++ +E +AR +
Sbjct: 189 AELLVQGEEEV-------------PAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIA 235
Query: 246 KLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVL 305
+ ++ DG +G H IP S RS + PS+ A L+
Sbjct: 236 TVEMV--IDGA--AGQQLPHKTPPRIPPKPKS-----------RSPTPPSIAAKAQLARQ 280
Query: 306 EPPQFVK---EPERHITA 320
+ P ++ P RH+ A
Sbjct: 281 QSPSPIRHSPSPVRHVRA 298
Score = 46.2 bits (108), Expect = 3e-04
Identities = 64/304 (21%), Positives = 114/304 (37%), Gaps = 32/304 (10%)
Query: 304 VLEPPQFVKEPERHITAEMEKVVDIPC--------QAKGVPPPSITWYKDAAVVEVEKLT 355
VL F + IT M +PC + P + WY + VE+++ +
Sbjct: 25865 VLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQSKPTAEVKWYHNG--VELQESS 25921
Query: 356 RFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV-----TSIAPNITRG 407
+ N G L+I DD+G ++ N GE L V T+ A
Sbjct: 25922 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDE 25981
Query: 408 PLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHI 467
+ +V ++ A S +++K + AS SV+ + E+ L S H
Sbjct: 25982 EVPRSVFPELTRTEAYAVS-------SFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 26034
Query: 468 SDAGTYTCLATNSRGVDEASA--DLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRV 525
+ A + A + ++E S + RI P+ +V +G A C +P
Sbjct: 26035 ASAEMKSA-ALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVP 26093
Query: 526 TIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL 584
T+ W + G L T + ++ + + IS + D G Y+ V ++ G L
Sbjct: 26094 TV--TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 26151
Query: 585 RVRQ 588
+++
Sbjct: 26152 TIQK 26155
Score = 45.4 bits (106), Expect = 6e-04
Identities = 52/240 (21%), Positives = 89/240 (37%), Gaps = 51/240 (21%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITL---ENTLVILSTVAPDAGR 180
+S G+ A + + P+P++ WF +G + PS+ +++L+IL T D G
Sbjct: 3468 ISMGDVATLSVT-VIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGE 3526
Query: 181 YYVQAVND-----------------KNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKN 223
Y A ND + D +T + ++E +GGP P + P +
Sbjct: 3527 YTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRC 3586
Query: 224 TSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGI-------SDHNRRLTIPNPTG 276
+ E T+ V P + W K+ L + + + + +P
Sbjct: 3587 AQGLPAIFEYTV--VGEPAPT----VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQR 3640
Query: 277 SDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVP 336
D+G Y C+A + + A L VL E + D PC+AK P
Sbjct: 3641 EDSGLYICKA---ENMLGESTCAAELLVL--------------LEDTDMTDTPCKAKSTP 3683
Score = 44.3 bits (103), Expect = 0.001
Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 459 SLLISPTHISD-AGTYTCLATNSRGVDEASADLVVWARTR--ITKPPQDQSVIKGTQASM 515
+L+I + D G Y C A N G SA L V R I + + V G A
Sbjct: 4297 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKF 4356
Query: 516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVISA 574
C + P V R+ W K G + IR + SL I +T D G YTC+ +
Sbjct: 4357 TCEIQSAPNV--RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4414
Query: 575 GGNDSRSAHLRV 586
G+ S +A L V
Sbjct: 4415 YGSVSCTATLTV 4426
Score = 42.7 bits (99), Expect = 0.004
Identities = 102/543 (18%), Positives = 186/543 (34%), Gaps = 78/543 (14%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDN 193
+ S P +V W+ +G ++ SS+I T + TL IL D+G Y N K
Sbjct: 25900 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG--- 25956
Query: 194 KTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKK 253
+ S TL V GG A SV + V++ + K
Sbjct: 25957 EASDYATLDV--TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK---------KT 26005
Query: 254 DGVLLSGGISDHNRRLTIPNPTGSD----AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQ 309
+ S + + ++T + S A A L S+ + +
Sbjct: 26006 SEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR 26065
Query: 310 FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVE---KLTRFRQRNDGGLQ 366
+ +P R +T + C G P P++TW + V+ ++T + ++ +
Sbjct: 26066 ILTKP-RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKST--FE 26122
Query: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETS 426
IS + D G + N+ G+ + L + +T V +
Sbjct: 26123 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKA--RVTE-----------KAVTSPPRV 26169
Query: 427 GAPRPAITWQKGERILASGSVQLPRF--TPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
+P P R+ + +V+ P+ +P S +SPT T
Sbjct: 26170 KSPEP--------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPT------------ 26209
Query: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHP 544
E L V A +IT+ + ++ A + C V W KDG L H
Sbjct: 26210 EKVQHLPVSAPPKITQFLKAEA--SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHF 26267
Query: 545 RIRLDRNGS--LHISQTWSGDIGTYTCRVISAGGNDS----------RSAHLRVRQLPHA 592
+ +G+ L I+ D G Y C + GG +S H +V ++
Sbjct: 26268 QFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISET 26327
Query: 593 PEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE--MSENNAPWTVLLASVDPKATSV 650
+ T + R +P ++ + + +S ++ + A+ +P+ T++
Sbjct: 26328 KKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAI 26387
Query: 651 TVK 653
K
Sbjct: 26388 WTK 26390
Score = 40.8 bits (94), Expect = 0.015
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 11/145 (7%)
Query: 77 MITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE-----KHQSVSHGEAAV 131
+IT+L + +R + N G R V + E + SV G+
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16751
Query: 132 IRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVND 188
I P I+ P+P +TW +DG + ++RI +T TL I T D G+Y + N
Sbjct: 16752 IEVP-ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANV 16810
Query: 189 KNGDNKTSQPITLTVENVGGPADPI 213
KT+ +T++ P P+
Sbjct: 16811 VG--QKTASIEIVTLDKPDPPKGPV 16833
Score = 40.4 bits (93), Expect = 0.019
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT---LVILSTVAPDAG 179
++ G+ V+ A I P P+ +W + G+ I PS IT T L I DAG
Sbjct: 13892 TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAG 13951
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
Y + A N + + +TV +V GP P+ + + K T
Sbjct: 13952 EYTITATNP---FGTKVEHVKVTVLDVPGPPGPVEISNVSAEKAT 13993
Score = 40.0 bits (92), Expect = 0.025
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 20/175 (11%)
Query: 416 GMSVVLACETSGAPRPAIT-WQKGERILASGSVQLPRFTPLESGS---LLISPTHISDAG 471
G S + C S P AIT W K S + P+ + G L I +SDAG
Sbjct: 4636 GSSAIFECLVS--PSTAITTWMKD----GSNIRESPKHRFIADGKDRKLHIIDVQLSDAG 4689
Query: 472 TYTCLATNSRGVDEASADLVV-WARTRITKPPQDQ-SVIKGTQASMVCGVTHDPRVTIRY 529
YTC+ ++A LVV R K +++ +V+KG + C + + V
Sbjct: 4690 EYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV---- 4745
Query: 530 IWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVISAGGNDSRS 581
+W KDG + E RI G +L I+ D GTYT V +A + S
Sbjct: 4746 VWRKDGKIV-VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSS 4799
Score = 39.3 bits (90), Expect = 0.043
Identities = 54/219 (24%), Positives = 84/219 (38%), Gaps = 29/219 (13%)
Query: 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELT---------KFSLEYRY 76
P F +PV + LEG G E W H+ +++ K
Sbjct: 1411 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 77 MITSLDRTHAGFYRCIVRNRMGA------LLQRQTEVQVAYMGSFEEGEKHQSVSHGEAA 130
+I + +G + + +NR G L E QV M F E K+ ++ G
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPM--FVEKLKNVNIKEGSRL 1527
Query: 131 VIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT-----LVILSTVAPDAGRYYVQA 185
++ R P P + W ++ I P I +E T L I STV+ D+ Y A
Sbjct: 1528 EMKV-RATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA 1586
Query: 186 VNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
+N K G + T + + VE A+P +I P+ T
Sbjct: 1587 IN-KAGRDTTRCKVNVEVEF----AEPEPERKLIIPRGT 1620
Score = 38.9 bits (89), Expect = 0.056
Identities = 39/150 (26%), Positives = 59/150 (39%), Gaps = 16/150 (10%)
Query: 76 YMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAY-----MGSFEEGEKHQSVSH---G 127
+ +TSL+ +R +N G R+T V + + + Q H G
Sbjct: 23197 HTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAG 23256
Query: 128 EAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAI---TLENTLVILSTVAPDAGRYYVQ 184
+ P IA P P +WF G K+ S R+ + T L I T D G Y ++
Sbjct: 23257 RPVELVIP-IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23315
Query: 185 AVNDKNGDNKTSQPI-TLTVENVGGPADPI 213
KN TS+ I + ++ G P PI
Sbjct: 23316 L---KNVTGTTSETIKVIILDKPGPPTGPI 23342
Score = 38.9 bits (89), Expect = 0.056
Identities = 58/210 (27%), Positives = 85/210 (40%), Gaps = 29/210 (13%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSR-IAITLEN-----TLVILSTVAPDAGRYYVQAVNDKN 190
I P+P VTW++ G+KI P T E+ L I S D Y V A N K
Sbjct: 25216 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARN-KY 25274
Query: 191 GDNKTSQPITLTVENVGGPAD-PIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHI 249
G++ +T+T+ P D + P N G S V E + P L
Sbjct: 25275 GEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANAECQEGQS-VCFEIRVSGIPPPTLK- 25330
Query: 250 IWKKDGVLLSGGISDH-------NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYL 302
W+KDG LS G + L I + D GYY V +++ S A+L
Sbjct: 25331 -WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR---VTATNTAGSTSCQAHL 25386
Query: 303 SV----LEPPQF--VKEPERHITAEMEKVV 326
V + +F +E ERH+ +++K +
Sbjct: 25387 QVERLRYKKQEFKSKEEHERHVQKQIDKTL 25416
Score = 38.5 bits (88), Expect = 0.073
Identities = 48/178 (26%), Positives = 71/178 (39%), Gaps = 11/178 (6%)
Query: 401 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESG- 458
AP I TV G G P P W K G +I S + + P ++
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW--YWPEDNVC 2088
Query: 459 SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVI---KGTQASM 515
L+I D+ + A N G + A L+V A+ IT + Q V+ K T A+
Sbjct: 2089 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATF 2148
Query: 516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVI 572
C T +P V ++ W KDG + R+ DR L I + D Y+C ++
Sbjct: 2149 ECE-TSEPFVKVK--WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Score = 37.4 bits (85), Expect = 0.16
Identities = 40/183 (21%), Positives = 75/183 (40%), Gaps = 14/183 (7%)
Query: 40 EGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGA 99
+G + +L E + W +N+E K + ++ I L +R N G
Sbjct: 23960 DGGKEILGYWVEYRQSGDSAWKKSNKERIK---DKQFTIGGLLEATEYEFRVFAENETGL 24016
Query: 100 LLQRQTEVQVAYMGSFEEGE------KHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
R+T + + + E K + GEAA + +I P P + W+R G++
Sbjct: 24017 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKE 24075
Query: 154 IPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPA 210
+ S + ++ + +TL +++ D G Y A N+ G+ +TS + L P
Sbjct: 24076 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEV-GEVETSSKLLLQATPQFHPG 24134
Query: 211 DPI 213
P+
Sbjct: 24135 YPL 24137
Score = 37.0 bits (84), Expect = 0.21
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGL 370
EP R + E + C+ G P P + WY + ++ K RFR R DG L I
Sbjct: 1802 EPVRVLEGETAR---FRCRVTGYPQPKVNWYLNGQLIRKSK--RFRVRYDGIHYLDIVDC 1856
Query: 371 VPDDTGMFQCFARNAAGEVQTSTYLAV 397
DTG + A N G ++ L +
Sbjct: 1857 KSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 36.6 bits (83), Expect = 0.28
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 17/162 (10%)
Query: 56 LEFKWLHNN--------RELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEV 107
+E +WL NN ++ +R I + G YR I +++ + + ++
Sbjct: 6443 VEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK-----EARAKL 6497
Query: 108 QVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENT 167
++A + ++ V G+ + P A +P+ + WF++ + + + +
Sbjct: 6498 ELAAAPKIKTADQDLVVDVGKPLTMVVPYDA-YPKAEAEWFKENEPLSTKTIDTTAEQTS 6556
Query: 168 LVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGP 209
IL D GRY + + +K+G K I L V +V GP
Sbjct: 6557 FRILEAKKGDKGRYKI-VLQNKHG--KAEGFINLKVIDVPGP 6595
Score = 36.2 bits (82), Expect = 0.36
Identities = 35/147 (23%), Positives = 56/147 (38%), Gaps = 10/147 (6%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGE--------KHQSV 124
E +Y +T L +R + N G V E E + Q +
Sbjct: 10674 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 10733
Query: 125 SHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQ 184
G+ + A I P P+VTW ++ R P +RI +T + + + A + G Y
Sbjct: 10734 KVGDTLRLSAI-IKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10792
Query: 185 AVNDKNGDNKTSQPITLTVENVGGPAD 211
V + G +KT L ++ G P D
Sbjct: 10793 TVENPAG-SKTVSVKVLVLDKPGPPRD 10818
Score = 35.4 bits (80), Expect = 0.61
Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 59 KWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEG 118
KW+ + + +E +T L+ YR NR GA + ++ + + E
Sbjct: 7136 KWVACGEPVAETKME----VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 7191
Query: 119 EKHQSVSHGEAAVIRA-------PRIASFPQPQVTWFRDGRKIPPSSRIAIT---LENTL 168
E V ++A + P+P++TW + + RI I ++T+
Sbjct: 7192 EIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTV 7251
Query: 169 VILSTVAPDAGRYYVQAVN 187
I+ + D G Y ++AVN
Sbjct: 7252 TIVDSKRSDTGTYIIEAVN 7270
Score = 35.0 bits (79), Expect = 0.80
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 124 VSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLE--NTLVILSTVAPDAGRY 181
V GE A R R+ +PQP+V W+ +G+ I S R + + + L I+ + D G
Sbjct: 1806 VLEGETARFRC-RVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1864
Query: 182 YVQAVN 187
V A N
Sbjct: 1865 KVTAEN 1870
Score = 35.0 bits (79), Expect = 0.80
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 137 IASFPQPQVTWFRDGRKIPPSSRIAITLE---NTLVILSTVAPDAGRYYVQAVNDKNGDN 193
I S P + WF+ GR+I S + +I ++L IL T D G Y +A N+ +
Sbjct: 4360 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVS 4419
Query: 194 KTSQPITLTVENVGG 208
T+ TLTV GG
Sbjct: 4420 CTA---TLTVTVPGG 4431
Score = 35.0 bits (79), Expect = 0.80
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 505 QSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLD-RNGSLHISQTWSGD 563
+S G+ A C V+ +T W KDG+ + R D ++ LHI D
Sbjct: 4631 ESEFVGSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSD 4687
Query: 564 IGTYTCRVISAGGNDSRSAHLRVRQLP 590
G YTC + + +A L V +LP
Sbjct: 4688 AGEYTCVLRLGNKEKTSTAKLVVEELP 4714
Score = 34.7 bits (78), Expect = 1.0
Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 53 SWPLEFKWLHNNREL-TKFS--LEYRYMITSLDRTHAGFYRCIVRNRMGALLQ-RQTEVQ 108
S+ +E + L N R L FS LE + ++ L A +R I +N GA+ +
Sbjct: 14893 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 14952
Query: 109 VAYMGSFEEGEKHQSVSHGEAAVIRAPR-------IASFPQPQVTWFRDGRKIPPSSRIA 161
+ E + V + +++A ++ P P + W +DG+++ ++++
Sbjct: 14953 ITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE 15012
Query: 162 ITL---ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTII 218
I + LV + D+G Y + A N G K + + ++ G P P+A T +
Sbjct: 15013 IKIADFSTNLVNKDSTRRDSGAYTLTATN-PGGFAKHIFNVKV-LDRPGPPEGPLAVTEV 15070
Query: 219 IPPK 222
K
Sbjct: 15071 TSEK 15074
Score = 34.7 bits (78), Expect = 1.0
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 141 PQPQVTWFRDGRKIPPSSRIAITLENTLVILS---TVAPDAGRYYVQAVNDKNGDNKTSQ 197
PQ V W +DG+ + ++R+ ++ T+ LS D G Y + N +
Sbjct: 18925 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV---SNSAGSITV 18981
Query: 198 PITLTVENVGGPADPI 213
PIT+ V + GP PI
Sbjct: 18982 PITIIVLDRPGPPGPI 18997
Score = 33.5 bits (75), Expect = 2.3
Identities = 57/314 (18%), Positives = 111/314 (35%), Gaps = 26/314 (8%)
Query: 94 RNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
R + GA Q E M SF +K + ++ E + + + S +V++F +
Sbjct: 4131 RIQQGAKTSLQEE-----MDSFSGSQKVEPITEPE---VESKYLIS--TEEVSYFNVQSR 4180
Query: 154 IPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENV-GGPADP 212
+ +T ++S D + + + ++ T + T+ ++ GG
Sbjct: 4181 VKYLDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKE 4240
Query: 213 IAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG-----ISDHNR 267
P I P +T G + NA+ + W + L+ + D N
Sbjct: 4241 DGPMIHTPLVDTVSEEGDIVHLTTSITNAK-----EVNWYFENKLVPSDEKFKCLQDQNT 4295
Query: 268 RLTIPNPTGSD--AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
+ + ++ G Y CEA+ S + + + P +K + + +
Sbjct: 4296 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP--VIKRKIEPLEVALGHL 4353
Query: 326 VDIPCQAKGVPPPSITWYKDAA-VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARN 384
C+ + P W+K + E +K + + L+I D G + C A N
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASN 4413
Query: 385 AAGEVQTSTYLAVT 398
G V + L VT
Sbjct: 4414 EYGSVSCTATLTVT 4427
Score = 33.5 bits (75), Expect = 2.3
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Query: 123 SVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRI-AITLENT--LVILSTVAPDAG 179
+V GE + P I P P VTW +D + ++R+ A + EN L I D G
Sbjct: 15661 TVLAGEDLKVDVPFIGR-PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVG 15719
Query: 180 RYYVQAVNDKNGDNKTSQPITLTVENVGGPADPI 213
Y V+ N +T I L + G P P+
Sbjct: 15720 HYVVKLTNSAGEAIETLNVIVL--DKPGPPTGPV 15751
Score = 33.1 bits (74), Expect = 3.0
Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 18/155 (11%)
Query: 73 EYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQV-----AYMG-------SFEEGEK 120
E +++I+ L + +R RN +G++ V +Y G + E K
Sbjct: 20327 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVK 20386
Query: 121 HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR 180
+++ G + +RA I+ P P + W++D +++ ++ + + ENT + S + DA R
Sbjct: 20387 YRA---GTSVKLRAG-ISGKPAPTIEWYKDDKELQTNALVCV--ENTTDLASILIKDADR 20440
Query: 181 YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAP 215
K + S T+ V+ + P P P
Sbjct: 20441 LNSGCYELKLRNAMGSASATIRVQILDKPGPPGGP 20475
Score = 31.6 bits (70), Expect = 8.9
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 1/86 (1%)
Query: 427 GAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEA 486
G P + W + L + + +L SL + D+G TC ATN G D
Sbjct: 1684 GDPTMVVEWLHDGKPLEAAN-RLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHT 1742
Query: 487 SADLVVWARTRITKPPQDQSVIKGTQ 512
SA L+V + + Q KG Q
Sbjct: 1743 SATLIVKDEKSLVEESQLPEGRKGLQ 1768
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 245 bits (626), Expect = 3e-64
Identities = 256/1043 (24%), Positives = 424/1043 (40%), Gaps = 106/1043 (10%)
Query: 1 MWGLLIWTLLALHQIRAARAQDD--VSPYFKTEPVRT---QVHLEGNRLVLTCMAEGSWP 55
MW L+ ++ A +++D P F+ +P+ T + LEG ++ L C A S
Sbjct: 3 MWLLVSHLVIISITTCLAVSEEDKGFGPIFEEQPINTIYPEESLEG-KVSLNCRARASPF 61
Query: 56 LEFKWLHNNRELTKFSLEY-----RYMITSLDRTH-AGFYRCIVRNRMGALLQRQTEVQV 109
+KW NN ++ S Y +I + D+ AG Y C+ N G + + +
Sbjct: 62 PVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSF 121
Query: 110 AYMGSFEEGEKHQ-SVSHGEAAVIRAPRIASFPQP-QVTWFRDGRKI---PPSSRIAITL 164
Y+ F E+ + V G+ V+ FP W + + R
Sbjct: 122 GYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQT 181
Query: 165 ENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNT 224
L I + A D G Y + + S+ I L + P I++ K+
Sbjct: 182 NGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPL-IPIPERTTKPYPADIVVQFKDV 240
Query: 225 SVVAGTSEVTLECVANARPLIKLHIIWKK--DGVLLSGGISDHNRRLTIPNPTGSDAGYY 282
+ G + VTLEC A P+ + W+K + + + IS L I N D G Y
Sbjct: 241 YALMGQN-VTLECFALGNPVPDIR--WRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIY 297
Query: 283 ECEAVLRSSSVPSVVRG-----AYLSVLEPPQFVKEPERHIT-AEMEKVVDI--PCQAKG 334
ECEA +RG A + V P++V+ HI E++ D+ PC A G
Sbjct: 298 ECEA--------ENIRGKDKHQARIYVQAFPEWVE----HINDTEVDIGSDLYWPCVATG 345
Query: 335 VPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTY 394
P P+I W K+ + G L++ + ++ GM+QC A N G + +
Sbjct: 346 KPIPTIRWLKNGYAY-----------HKGELRLYDVTFENAGMYQCIAENTYGAIYANAE 394
Query: 395 LAVTSIAPNITRGPLDSTVI--DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRF 452
L + ++AP P+ ++ G V++ C+ AP+P +W KG L + S R
Sbjct: 395 LKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSS----RI 450
Query: 453 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQ 512
E GSL I+ +D G YTC A N+RG ++ LV+ TRI P + + G
Sbjct: 451 LIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGEN 510
Query: 513 ASMVCGVTHDPRVTIRYIWEKDGATL-----GTESHPRIRLDRNGSLHISQTWSGDIGTY 567
A+M C + DP + + ++W +G + LD NG L I G Y
Sbjct: 511 ATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRY 570
Query: 568 TCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYIL 627
TC + N S SA L VR P P + + ++ LTW++ D +SP+ +Y +
Sbjct: 571 TCTAQTIVDNSSASADLVVRGPPGPPGG--LRIEDIRATSVALTWSRGSDNHSPISKYTI 628
Query: 628 EMSENNAPWTVLL-----ASVDPKATSVTVKG-----LVPARSYQFRLCAVNDVGKGQFS 677
+ T+L A DP ++ L+P Y+FR+ A N +G+G+ S
Sbjct: 629 QTK------TILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPS 682
Query: 678 KDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPV 737
+ R+ P P +V G N+ + I W P + G GYI+ +
Sbjct: 683 IPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFD--- 739
Query: 738 GYQFK--NITDADVNNLLLED--LIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTV 793
G ++K +T+ D + +D + T ++++V A+N+ G G YS + Q P+
Sbjct: 740 GEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSE 799
Query: 794 PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSI 853
P V + +S+ I W + I + Y++ W +EE R
Sbjct: 800 APTEVGVKVLSSSEISVHWE----HVLEKIVESYQIRYWAAHDKEE---AANRVQVTSQE 852
Query: 854 HVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKV 913
+ + L T+YF V + G GP S T + P + S + +
Sbjct: 853 YSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYII 912
Query: 914 SWQE--PGEKNGILTGYRISWEEYNRTNTRV-THYLPNVTLEYRVTGLTALTTYTIEVAA 970
+W +TGY++ + + + ++ + + ++ + G Y +EV A
Sbjct: 913 TWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDG-----EYVVEVRA 967
Query: 971 MTSKGQGQVSASTISSGVPPELP 993
+ G G VS I SG P P
Sbjct: 968 HSDGGDGVVSQVKI-SGAPTLSP 989
Score = 132 bits (333), Expect = 3e-30
Identities = 107/404 (26%), Positives = 177/404 (43%), Gaps = 39/404 (9%)
Query: 1373 FRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPV 1432
+ TAQT A+ LVV R P PP + ED+RA SV L+W GSD SP+
Sbjct: 570 YTCTAQTIVDNSSASADLVV----RGPPGPPGGLRI--EDIRATSVALTWSRGSDNHSPI 623
Query: 1433 RYYTIQTRELPSGRW---ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
YTIQT+ + S W + N + L P+ Y+FRV ATN +G E S
Sbjct: 624 SKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSI 683
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGL 1549
S + T AAP+ AP+ + + I W P + + G G+ + ++
Sbjct: 684 PSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPF----- 738
Query: 1550 RGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY--ELDNLNKHRRYEIRMSVYNAVGE 1607
G W ++T ++ P +Y + + ++ +++++ +N G+
Sbjct: 739 ----------DGEEWKKVT-------VTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGD 781
Query: 1608 GPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQ 1667
GP S + + P+ AP V V +++++ V WE ++ Y+I +W A
Sbjct: 782 GPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEKIVESYQIRYWAAH 837
Query: 1668 RGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAP 1727
+ E S +L+NL T Y + V A N+AG GP S + T++A PS P
Sbjct: 838 DKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQP 897
Query: 1728 SSVKFSELTTTSVNVSWE--APQFPNGILEGYRLVYEPCSPVDG 1769
+ S + + ++W+ + GY+++Y P DG
Sbjct: 898 PRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDG 941
Score = 108 bits (269), Expect = 7e-23
Identities = 98/362 (27%), Positives = 154/362 (42%), Gaps = 23/362 (6%)
Query: 934 EYNRTNTRVTHYLPNVTLE------YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSG 987
++N+ N HY N L+ R L YT A T SA + G
Sbjct: 537 DFNKENI---HYQRNFMLDSNGELLIRNAQLKHAGRYTC--TAQTIVDNSSASADLVVRG 591
Query: 988 VPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQL 1047
P GPP L I +I SV L + G D + IS++ ++ + + + ++ +
Sbjct: 592 PP----GPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI 647
Query: 1048 SNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRT 1107
E + + DL P+ Y FR+ N +G PS PS +I+T A P++AP++V
Sbjct: 648 I-EGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 706
Query: 1108 ASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLE 1166
L + W PL + GN + GY + + DG K ++ D + E +
Sbjct: 707 GRNRELTITWAPLSREYHYGN--NFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMS 764
Query: 1167 EWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 1226
T ++V+V+AFN G GP+S V + + PS PT V +SS + V W V E
Sbjct: 765 PSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK 824
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
+V Y++ Y + + + SA+L L Y ++V A G G
Sbjct: 825 ----IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGP 880
Query: 1287 PS 1288
PS
Sbjct: 881 PS 882
Score = 85.9 bits (211), Expect = 4e-16
Identities = 116/491 (23%), Positives = 199/491 (40%), Gaps = 64/491 (13%)
Query: 1234 GYKVMYKEKDSDTQPRFWLVEGNSS--RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPP 1291
GY + + +++ Q F L R+AQL G+Y ++ D S +
Sbjct: 533 GYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIV------DNSSASAD 586
Query: 1292 ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQI-THRLNTTTANTATV 1350
++ R PGPP G+ ++R TSV L W + + I Y I T + + A
Sbjct: 587 LVVR---GPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKT 643
Query: 1351 E--VLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM- 1407
+ ++ + A L P Y FR+ A G GE ++ K D P P
Sbjct: 644 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGE--PSIPSNRIKTDGAAPNVAPSD 701
Query: 1408 VQQEDVRARSVLLSWEPGSDGLSPVRY-----YTIQTRELPSGRWALHSASVSHNASSFI 1462
V R R + ++W P S Y Y + + W +V++ +
Sbjct: 702 VGGGGGRNRELTITWAPLS---REYHYGNNFGYIVAFKPFDGEEW--KKVTVTNPDTGRY 756
Query: 1463 V---DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
V + + P T+++ +VKA N+ GD +S + + + Q AP EAPT + V +++ +
Sbjct: 757 VHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA-VINSAQDAPSEAPTEVGVKVLSSSEIS 815
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSM-YSMRNLSR 1578
+ W E + I+ ++IRY A ++TS YS R
Sbjct: 816 VHW----EHVLEKIVESYQIRY-----------WAAHDKEEAANRVQVTSQEYSAR---- 856
Query: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT 1638
L+NL +Y I + N+ G GP S E F +A P+ PR ++ + +
Sbjct: 857 -------LENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPR-IISSVRSGS 908
Query: 1639 QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMV 1698
+ +TW+ S + GYK+ + R + K ++S+++ + Y+V
Sbjct: 909 RYIITWDHVVALSNESTVTGYKVLY----RPDGQHDGKLYSTHKHSIEVP-IPRDGEYVV 963
Query: 1699 SVAAFNAAGDG 1709
V A + GDG
Sbjct: 964 EVRAHSDGGDG 974
Score = 84.0 bits (206), Expect = 2e-15
Identities = 102/446 (22%), Positives = 180/446 (40%), Gaps = 68/446 (15%)
Query: 895 PGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRIS--------WE---------EYNR 937
PGP G L +I TS+ ++W + + ++ Y I W+ E N
Sbjct: 593 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 652
Query: 938 TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISS-GVPPELPGPP 996
R +P + E+RV L +G+ + ++ I + G P + P
Sbjct: 653 EAARAVDLIPWMEYEFRVVATNTL-----------GRGEPSIPSNRIKTDGAAPNVA--P 699
Query: 997 TNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVG-----VVG----EGEEWLLIHQL 1047
+++G R +T+ + P +SR E G +V +GEEW +
Sbjct: 700 SDVGGGGGRNRELTITWAP-------LSR---EYHYGNNFGYIVAFKPFDGEEWKKVTVT 749
Query: 1048 SNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRT 1107
+ + + ++P T + +++ N G P S + I + Q P AP V ++
Sbjct: 750 NPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA-VINSAQDAPSEAPTEVGVKV 808
Query: 1108 ASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEE 1167
S + + + W + E Y+I+Y + + + V E +E+L
Sbjct: 809 LSSSEISVHWEHVLEKIVES------YQIRYWAAHDKEEAANRVQVTSQEYSARLENLLP 862
Query: 1168 WTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
T+Y ++V A N+ G GP S + T+++ PS P +S++ + S ++ W V
Sbjct: 863 DTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSV-RSGSRYIITWDHVVALS 921
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
V GYKV+Y+ D + + +S + G+YV V+V A + GDG
Sbjct: 922 NESTVTGYKVLYR-PDGQHDGKLYSTHKHSI-EVPIPRDGEYV---VEVRAHSDGGDGVV 976
Query: 1288 SH-----PPILERTLDDVPGPPMGIL 1308
S P L +L + P GIL
Sbjct: 977 SQVKISGAPTLSPSLLGLLLPAFGIL 1002
Score = 55.8 bits (133), Expect = 4e-07
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 5/130 (3%)
Query: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITR 1856
R+ A+T A++ G PGPPG + I ++++A+ WS G PI++
Sbjct: 569 RYTCTAQTIVDNSSASADLVV---RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISK 625
Query: 1857 YVIEARPSDEGLWDILIKDIPKEVSSYTFSMDI-LKPGVSYDFRVIAVNDYGFGTPSSPS 1915
Y I+ + W D P + + + L P + Y+FRV+A N G G PS PS
Sbjct: 626 YTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPS 685
Query: 1916 QSVPAQKANP 1925
+ A P
Sbjct: 686 NRIKTDGAAP 695
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 245 bits (625), Expect = 4e-64
Identities = 251/1016 (24%), Positives = 413/1016 (40%), Gaps = 104/1016 (10%)
Query: 26 PYFKTEPVRT---QVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY-----RYM 77
P F+ +P+ T + LEG ++ L C A S +KW NN ++ S Y +
Sbjct: 41 PIFEEQPINTIYPEESLEG-KVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLV 99
Query: 78 ITSLDRTH-AGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQ-SVSHGEAAVIRAP 135
I + D+ AG Y C+ N G + + + Y+ F E+ + V G+ V+
Sbjct: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
Query: 136 RIASFPQP-QVTWFRDGRKI---PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNG 191
FP W + + R L I + A D G Y +
Sbjct: 160 PPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSIT 219
Query: 192 DNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIW 251
+ S+ I L + P I++ K+ + G + VTLEC A P+ + W
Sbjct: 220 KSVFSKFIPL-IPIPERTTKPYPADIVVQFKDVYALMGQN-VTLECFALGNPVPDIR--W 275
Query: 252 KK--DGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG-----AYLSV 304
+K + + + IS L I N D G YECEA +RG A + V
Sbjct: 276 RKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEA--------ENIRGKDKHQARIYV 327
Query: 305 LEPPQFVKEPERHIT-AEMEKVVDI--PCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
P++V+ HI E++ D+ PC A G P P+I W K+ +
Sbjct: 328 QAFPEWVE----HINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAY-----------H 372
Query: 362 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI--DGMSV 419
G L++ + ++ GM+QC A N G + + L + ++AP P+ ++ G V
Sbjct: 373 KGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRV 432
Query: 420 VLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATN 479
++ C+ AP+P +W KG L + S R E GSL I+ +D G YTC A N
Sbjct: 433 IIECKPKAAPKPKFSWSKGTEWLVNSS----RILIWEDGSLEINNITRNDGGIYTCFAEN 488
Query: 480 SRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL- 538
+RG ++ LV+ TRI P + + G A+M C + DP + + ++W +G +
Sbjct: 489 NRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
Query: 539 ----GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE 594
LD NG L I G YTC + N S SA L VR P P
Sbjct: 549 FNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPG 608
Query: 595 HPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLL-----ASVDPKATS 649
+ + ++ LTW++ D +SP+ +Y ++ T+L A DP
Sbjct: 609 G--LRIEDIRATSVALTWSRGSDNHSPISKYTIQTK------TILSDDWKDAKTDPPIIE 660
Query: 650 VTVKG-----LVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTN 704
++ L+P Y+FR+ A N +G+G+ S + R+ P P +V G N
Sbjct: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
Query: 705 QSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFK--NITDADVNNLLLED--LIIW 760
+ + I W P + G GYI+ + G ++K +T+ D + +D +
Sbjct: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFD---GEEWKKVTVTNPDTGRYVHKDETMSPS 777
Query: 761 TNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFI 820
T ++++V A+N+ G G YS + Q P+ P V + +S+ I W +
Sbjct: 778 TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVL 833
Query: 821 NGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDG 880
I + Y++ W +EE R + + L T+YF V + G G
Sbjct: 834 EKIVESYQIRYWAAHDKEE---AANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCG 890
Query: 881 PRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWEEYNRT 938
P S T + P + S + ++W +TGY++ + +
Sbjct: 891 PPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQH 950
Query: 939 NTRV-THYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELP 993
+ ++ + + ++ + G Y +EV A + G G VS I SG P P
Sbjct: 951 DGKLYSTHKHSIEVPIPRDG-----EYVVEVRAHSDGGDGVVSQVKI-SGAPTLSP 1000
Score = 132 bits (333), Expect = 3e-30
Identities = 107/404 (26%), Positives = 177/404 (43%), Gaps = 39/404 (9%)
Query: 1373 FRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPV 1432
+ TAQT A+ LVV R P PP + ED+RA SV L+W GSD SP+
Sbjct: 581 YTCTAQTIVDNSSASADLVV----RGPPGPPGGLRI--EDIRATSVALTWSRGSDNHSPI 634
Query: 1433 RYYTIQTRELPSGRW---ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
YTIQT+ + S W + N + L P+ Y+FRV ATN +G E S
Sbjct: 635 SKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSI 694
Query: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGL 1549
S + T AAP+ AP+ + + I W P + + G G+ + ++
Sbjct: 695 PSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPF----- 749
Query: 1550 RGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY--ELDNLNKHRRYEIRMSVYNAVGE 1607
G W ++T ++ P +Y + + ++ +++++ +N G+
Sbjct: 750 ----------DGEEWKKVT-------VTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGD 792
Query: 1608 GPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQ 1667
GP S + + P+ AP V V +++++ V WE ++ Y+I +W A
Sbjct: 793 GPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEKIVESYQIRYWAAH 848
Query: 1668 RGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAP 1727
+ E S +L+NL T Y + V A N+AG GP S + T++A PS P
Sbjct: 849 DKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQP 908
Query: 1728 SSVKFSELTTTSVNVSWE--APQFPNGILEGYRLVYEPCSPVDG 1769
+ S + + ++W+ + GY+++Y P DG
Sbjct: 909 PRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDG 952
Score = 108 bits (269), Expect = 7e-23
Identities = 98/362 (27%), Positives = 154/362 (42%), Gaps = 23/362 (6%)
Query: 934 EYNRTNTRVTHYLPNVTLE------YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSG 987
++N+ N HY N L+ R L YT A T SA + G
Sbjct: 548 DFNKENI---HYQRNFMLDSNGELLIRNAQLKHAGRYTC--TAQTIVDNSSASADLVVRG 602
Query: 988 VPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQL 1047
P GPP L I +I SV L + G D + IS++ ++ + + + ++ +
Sbjct: 603 PP----GPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI 658
Query: 1048 SNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRT 1107
E + + DL P+ Y FR+ N +G PS PS +I+T A P++AP++V
Sbjct: 659 I-EGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
Query: 1108 ASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLE 1166
L + W PL + GN + GY + + DG K ++ D + E +
Sbjct: 718 GRNRELTITWAPLSREYHYGN--NFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMS 775
Query: 1167 EWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 1226
T ++V+V+AFN G GP+S V + + PS PT V +SS + V W V E
Sbjct: 776 PSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK 835
Query: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
+V Y++ Y + + + SA+L L Y ++V A G G
Sbjct: 836 ----IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGP 891
Query: 1287 PS 1288
PS
Sbjct: 892 PS 893
Score = 85.9 bits (211), Expect = 4e-16
Identities = 116/491 (23%), Positives = 199/491 (40%), Gaps = 64/491 (13%)
Query: 1234 GYKVMYKEKDSDTQPRFWLVEGNSS--RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPP 1291
GY + + +++ Q F L R+AQL G+Y ++ D S +
Sbjct: 544 GYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIV------DNSSASAD 597
Query: 1292 ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQI-THRLNTTTANTATV 1350
++ R PGPP G+ ++R TSV L W + + I Y I T + + A
Sbjct: 598 LVVR---GPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKT 654
Query: 1351 E--VLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM- 1407
+ ++ + A L P Y FR+ A G GE ++ K D P P
Sbjct: 655 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGE--PSIPSNRIKTDGAAPNVAPSD 712
Query: 1408 VQQEDVRARSVLLSWEPGSDGLSPVRY-----YTIQTRELPSGRWALHSASVSHNASSFI 1462
V R R + ++W P S Y Y + + W +V++ +
Sbjct: 713 VGGGGGRNRELTITWAPLS---REYHYGNNFGYIVAFKPFDGEEW--KKVTVTNPDTGRY 767
Query: 1463 V---DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
V + + P T+++ +VKA N+ GD +S + + + Q AP EAPT + V +++ +
Sbjct: 768 VHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA-VINSAQDAPSEAPTEVGVKVLSSSEIS 826
Query: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSM-YSMRNLSR 1578
+ W E + I+ ++IRY A ++TS YS R
Sbjct: 827 VHW----EHVLEKIVESYQIRY-----------WAAHDKEEAANRVQVTSQEYSAR---- 867
Query: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT 1638
L+NL +Y I + N+ G GP S E F +A P+ PR ++ + +
Sbjct: 868 -------LENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPR-IISSVRSGS 919
Query: 1639 QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMV 1698
+ +TW+ S + GYK+ + R + K ++S+++ + Y+V
Sbjct: 920 RYIITWDHVVALSNESTVTGYKVLY----RPDGQHDGKLYSTHKHSIEVP-IPRDGEYVV 974
Query: 1699 SVAAFNAAGDG 1709
V A + GDG
Sbjct: 975 EVRAHSDGGDG 985
Score = 84.0 bits (206), Expect = 2e-15
Identities = 102/446 (22%), Positives = 180/446 (40%), Gaps = 68/446 (15%)
Query: 895 PGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRIS--------WE---------EYNR 937
PGP G L +I TS+ ++W + + ++ Y I W+ E N
Sbjct: 604 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 663
Query: 938 TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISS-GVPPELPGPP 996
R +P + E+RV L +G+ + ++ I + G P + P
Sbjct: 664 EAARAVDLIPWMEYEFRVVATNTL-----------GRGEPSIPSNRIKTDGAAPNVA--P 710
Query: 997 TNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVG-----VVG----EGEEWLLIHQL 1047
+++G R +T+ + P +SR E G +V +GEEW +
Sbjct: 711 SDVGGGGGRNRELTITWAP-------LSR---EYHYGNNFGYIVAFKPFDGEEWKKVTVT 760
Query: 1048 SNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRT 1107
+ + + ++P T + +++ N G P S + I + Q P AP V ++
Sbjct: 761 NPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA-VINSAQDAPSEAPTEVGVKV 819
Query: 1108 ASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEE 1167
S + + + W + E Y+I+Y + + + V E +E+L
Sbjct: 820 LSSSEISVHWEHVLEKIVES------YQIRYWAAHDKEEAANRVQVTSQEYSARLENLLP 873
Query: 1168 WTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEAD 1227
T+Y ++V A N+ G GP S + T+++ PS P +S++ + S ++ W V
Sbjct: 874 DTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSV-RSGSRYIITWDHVVALS 932
Query: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287
V GYKV+Y+ D + + +S + G+YV V+V A + GDG
Sbjct: 933 NESTVTGYKVLYR-PDGQHDGKLYSTHKHSI-EVPIPRDGEYV---VEVRAHSDGGDGVV 987
Query: 1288 SH-----PPILERTLDDVPGPPMGIL 1308
S P L +L + P GIL
Sbjct: 988 SQVKISGAPTLSPSLLGLLLPAFGIL 1013
Score = 55.8 bits (133), Expect = 4e-07
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 5/130 (3%)
Query: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITR 1856
R+ A+T A++ G PGPPG + I ++++A+ WS G PI++
Sbjct: 580 RYTCTAQTIVDNSSASADLVV---RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISK 636
Query: 1857 YVIEARPSDEGLWDILIKDIPKEVSSYTFSMDI-LKPGVSYDFRVIAVNDYGFGTPSSPS 1915
Y I+ + W D P + + + L P + Y+FRV+A N G G PS PS
Sbjct: 637 YTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPS 696
Query: 1916 QSVPAQKANP 1925
+ A P
Sbjct: 697 NRIKTDGAAP 706
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 243 bits (619), Expect = 2e-63
Identities = 275/1056 (26%), Positives = 422/1056 (39%), Gaps = 111/1056 (10%)
Query: 218 IIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGS 277
++ P +T V G+S V L C A + P K+ WKKDG L+ +SD R+L P GS
Sbjct: 56 LVEPVDTLSVRGSS-VILNCSAYSEPSPKIE--WKKDGTFLNL-VSDDRRQLL---PDGS 108
Query: 278 --------------DAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEME 323
D GYY+C A + S + R A L V P+F +PE
Sbjct: 109 LFISNVVHSKHNKPDEGYYQCVATVESLGT-IISRTAKLIVAGLPRFTSQPEPSSVYAGN 167
Query: 324 KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFAR 383
+ + C+ P + W ++ + ++ R + G L IS D G+++C
Sbjct: 168 NAI-LNCEVNADLVPFVRWEQNRQPLLLDD--RVIKLPSGMLVISNATEGDGGLYRCVVE 224
Query: 384 NA-----AGEVQTSTYLAVTSIAPNI-TRGPLDSTVIDGMSVVLACETSGAPRPAITWQK 437
+ + EV+ I+ + + P + G VVL C SG P P I W K
Sbjct: 225 SGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMK 284
Query: 438 GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTR 497
E L + S + R L GSL IS DAGTY C+A N EA A+L V A+
Sbjct: 285 NEEALDTESSE--RLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPE 342
Query: 498 ITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHIS 557
K P + + C VT P T++ W K+G + + +I + N L +
Sbjct: 343 FLKQPTNIYAHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKEHN--LQVL 398
Query: 558 QTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ--------LPHAPEHPVATLSTVERRAIN 609
D G Y C + GN A L + + LP AP VA+L V R I
Sbjct: 399 GLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASL--VSTRFIK 456
Query: 610 LTWTKPF-DGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAV 668
LTW P D + + Y + ++ + + P VT++ L+PA Y FR+ A
Sbjct: 457 LTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQ 516
Query: 669 NDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYII 728
N G G+ S + PE P N+ A + SI + W+ P NG ++ Y +
Sbjct: 517 NKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSG--NGEIQNYKL 574
Query: 729 RYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQ 788
Y + G + D ++ + L +T Y V AYN G GV + V TL
Sbjct: 575 YY----MEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLS 630
Query: 789 GVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPN 848
VP+ P N+ E NS +I W P+P NG GYK+ + ++ +VT
Sbjct: 631 DVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGT 690
Query: 849 FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHED------VPGPVGHLS 902
+ + GL + TEY V T G GP + T E VP L
Sbjct: 691 QLSQL----IEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLH 746
Query: 903 FSEILDTSLKVSWQEPGEKNGILTGYRISWEEYN-RTNTRVTHYLPNVTLEYRVTGLTAL 961
++ TS+ VSW P +N ++ GY I + + T Y Y + L
Sbjct: 747 VRPLV-TSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRY---YTIENLDPS 802
Query: 962 TTYTIEVAAMTSKGQG----------------QVSASTIS---SGVPPELP-GPPTNLGI 1001
+ Y I + A + G+G +V I+ + VP P PP +
Sbjct: 803 SHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQA 862
Query: 1002 SNIGPRSVTLQFR----PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSME 1057
S + ++ + + P + T + V + + + + S
Sbjct: 863 SILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTK------YKNANATTLSYL 916
Query: 1058 VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSL--RTASETSLWL 1115
V L P T Y F + +S S + T + P P +V++ + ++ +
Sbjct: 917 VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHG-TTFELVPTSPPKDVTVVSKEGKPKTIIV 975
Query: 1116 RWMPLPEMEYNGNPESVGYKIKYS---RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYR 1172
W P E N + GY I YS ++ H + VV +R+ + I++L T Y
Sbjct: 976 NWQPPSE----ANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRL--THQIQELTLDTPYY 1029
Query: 1173 VQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSA 1208
++QA N+ G GP S+ V RT ++ S N A
Sbjct: 1030 FKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQA 1065
Score = 159 bits (402), Expect = 3e-38
Identities = 164/623 (26%), Positives = 253/623 (40%), Gaps = 59/623 (9%)
Query: 954 RVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGP----PTNLGISNIGPRSV 1009
+V GL + A G Q A I P GP P ++ S + R +
Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFI 455
Query: 1010 TLQFR-PGYDGK-TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCY 1067
L +R P D +++ + + G+ E E ++ P + + +L P T Y
Sbjct: 456 KLTWRTPASDPHGDNLTYSVFYTKEGIARERVE------NTSHPGEMQVTIQNLMPATVY 509
Query: 1068 SFRMRQVNIVGTSPPSQPSR-KIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYN 1126
FR+ N G+ S P R + Q P AP N+ AS TS+ + W E +
Sbjct: 510 IFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAP-NLRAYAASPTSITVTW----ETPVS 564
Query: 1127 GNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPW 1186
GN E YK+ Y T D YTI L+++TEY +V A+N G G
Sbjct: 565 GNGEIQNYKLYYMEKG----TDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVS 620
Query: 1187 SQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDT 1246
+ V RT VPS+ P N+S S S+++ W A +NG + GYK+ Y++ +
Sbjct: 621 TPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKS 680
Query: 1247 QPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPS---HPPILERTLDDVPGP 1303
LV G + S + GL + Y +V A T G G + E LD+ P
Sbjct: 681 DVTETLVSG-TQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVP 739
Query: 1304 PM-GILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTA 1362
+ L TS+ + W PP N ++ Y I + + + A T V+ R YT
Sbjct: 740 EVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDY---KQRYYTI 796
Query: 1363 TGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRD-------------RPQPPSRPMVQ 1409
L P S Y+ + A G G VT D P P PM+
Sbjct: 797 ENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMP 856
Query: 1410 QEDVRAR-----SVLLSWE----PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASS 1460
V+A ++ ++W P ++ RYYT++ + +A+ + S
Sbjct: 857 PVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANAT--TLS 914
Query: 1461 FIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH--TTTSV 1518
++V LKP T Y+F V T S +S + TT + P P ++V ++
Sbjct: 915 YLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHG-TTFELVPTSPPKDVTVVSKEGKPKTI 973
Query: 1519 LIRWQPPAEDKINGILLGFRIRY 1541
++ WQPP+E NG + G+ I Y
Sbjct: 974 IVNWQPPSE--ANGKITGYIIYY 994
Score = 152 bits (385), Expect = 3e-36
Identities = 236/1077 (21%), Positives = 390/1077 (36%), Gaps = 147/1077 (13%)
Query: 502 PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWS 561
P D ++G+ + C +P I W+KDG L S R +L +GSL IS
Sbjct: 59 PVDTLSVRGSSVILNCSAYSEPSPKIE--WKKDGTFLNLVSDDRRQLLPDGSLFISNVVH 116
Query: 562 G-----DIGTYTC--RVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTK 614
D G Y C V S G SR+A L V LP P + AI
Sbjct: 117 SKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAI-----L 171
Query: 615 PFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
+ N+ L+ ++ +N P + + + + + +R C V G
Sbjct: 172 NCEVNADLVPFV-RWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYR-CVVESGGPP 229
Query: 675 QFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAG 734
++S + E LP+ P+ + ++ QP P G + ++ +G
Sbjct: 230 KYSDEVELKVLPD------PEVI-------SDLVFLKQPSPLVRVIG--QDVVLPCVASG 274
Query: 735 LPVGY--QFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYS----------SKV 782
LP KN D + E L++ +E++ G Y
Sbjct: 275 LPTPTIKWMKNEEALDTESS--ERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQ 332
Query: 783 TEWTLQGVPTV--PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEV 840
E T+Q P P N++A + + + G +I +
Sbjct: 333 AELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIP------SDY 386
Query: 841 TMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHED-----VP 895
+ N Q V GL K E F + G+ ++ H +P
Sbjct: 387 FKIVKEHNLQ-------VLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLP 439
Query: 896 GPVGHLSFSEILDTSLKVSWQEPG-EKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYR 954
+ S + +K++W+ P + +G Y + + + RV + ++
Sbjct: 440 SAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVT 499
Query: 955 VTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPP-ELPGPPTNLGISNIGPRSVTLQF 1013
+ L T Y V A G G+ SA P +LPGP NL P S+T+ +
Sbjct: 500 IQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTW 559
Query: 1014 RPGYDGKTSISRW-LVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMR 1072
G I + L + G E + + H S + L +T YSFR+
Sbjct: 560 ETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSH---------SYTINGLKKYTEYSFRVV 610
Query: 1073 QVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESV 1132
N G S P ++TL P AP N+SL + S+ + W P NG +
Sbjct: 611 AYNKHGPGV-STPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNG--QIT 667
Query: 1133 GYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVG 1192
GYKI+Y ++ +V + IE L+ TEY +V A G+GP + +
Sbjct: 668 GYKIRYRKASRKSDVTETLVSG-TQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSA 726
Query: 1193 RTRES---------VPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMY---- 1239
T ES VPSS +V L T S++V W+ P ++N +V GY + Y
Sbjct: 727 ETFESDLDETRVPEVPSS--LHVRPLVT---SIVVSWT--PPENQNIVVRGYAIGYGIGS 779
Query: 1240 ---KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT 1296
+ D + R++ +E S Y + + AF +G+G P + + R
Sbjct: 780 PHAQTIKVDYKQRYYTIENLDPSSH----------YVITLKAFNNVGEGIPLYESAVTRP 829
Query: 1297 LDD---------------VPGP-----PMGILFPEVRTTSVRLIWQPPAAPNG--IILAY 1334
D VP P P+G+ + ++R+ W + P I +
Sbjct: 830 HTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSR 889
Query: 1335 QITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITA---QTRKGWGEAAEALV 1391
T R T + + Y TGLKP ++Y F + + W A
Sbjct: 890 YYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHG-- 947
Query: 1392 VTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGR---WA 1448
TT + PP V ++ + ++++++W+P S+ + Y I + W
Sbjct: 948 -TTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWV 1006
Query: 1449 LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAP 1505
+ V N + + L T Y F+++A N G SE + T + D+ P
Sbjct: 1007 IEP--VVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMP 1061
Score = 144 bits (364), Expect = 7e-34
Identities = 179/656 (27%), Positives = 273/656 (41%), Gaps = 60/656 (9%)
Query: 1095 PPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQD 1154
P AP +V S + L W P + +G +++ Y + Y++ +G +
Sbjct: 437 PLPSAPRDVVASLVSTRFIKLTWRT-PASDPHG--DNLTYSVFYTK-EGIARERVENTSH 492
Query: 1155 RVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPT-NVSALATTS 1213
E TI++L T Y +V A N GSG S + T+ V GP N+ A A +
Sbjct: 493 PGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASP 552
Query: 1214 SSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYE 1273
+S+ V W E P + NG + YK+ Y EK +D + + SS S + GL KY Y
Sbjct: 553 TSITVTW-ETPVSG-NGEIQNYKLYYMEKGTDKEQDVDV----SSHSYTINGLKKYTEYS 606
Query: 1274 VQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTT-SVRLIWQPPA--APNGI 1330
+V+A+ + G G S P + RTL DVP L EVR + S+ + WQPPA NG
Sbjct: 607 FRVVAYNKHGPGV-STPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQ 665
Query: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
I Y+I +R + + T +++ + GL + Y FR+ A T G G A + L
Sbjct: 666 ITGYKIRYR-KASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWL 724
Query: 1391 VVTTEKRDR-----PQPPS----RPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRE 1441
T + D P+ PS RP+V S+++SW P + VR Y I
Sbjct: 725 SAETFESDLDETRVPEVPSSLHVRPLVT-------SIVVSWTPPENQNIVVRGYAIG--- 774
Query: 1442 LPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAP 1501
G + V + + ++ L P + Y +KA N++G+ ES ++T
Sbjct: 775 YGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYES-AVTRPHTDT 833
Query: 1502 DEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRY--------RELLYEGLRGFT 1553
E + P+T PP + + IL IR + R +T
Sbjct: 834 SEVDLFVINAPYTPVPDPTPMMPPVGVQAS-ILSHDTIRITWADNSLPKHQKITDSRYYT 892
Query: 1554 LRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPP 1613
+R N A + Y N + S Y + L + YE + V S
Sbjct: 893 VRWKTNIPAN-----TKYKNANATTLS---YLVTGLKPNTLYEFSVMVTKGRRSSTWSMT 944
Query: 1614 QEVFVGEAVPTAAPRNVVV---HGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGN 1670
E VPT+ P++V V G T + V W+PP NG I GY IY+
Sbjct: 945 AHGTTFELVPTSPPKDVTVVSKEGKPKTII-VNWQPP--SEANGKITGYIIYYSTDVNAE 1001
Query: 1671 LTERVKTLFLAENSV-KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPS 1725
+ + V + +++ LT T Y + A N+ G GP S Q +T +A S
Sbjct: 1002 IHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSS 1057
Score = 130 bits (328), Expect = 1e-29
Identities = 157/668 (23%), Positives = 268/668 (40%), Gaps = 100/668 (14%)
Query: 1296 TLDDVPGPPMGILFPEVRTTSVRLIWQPPAA-PNGIILAYQITHRLNTTTANTATVEVLA 1354
T +P P ++ V T ++L W+ PA+ P+G L Y + + A
Sbjct: 434 TTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYT-KEGIARERVENTSH 492
Query: 1355 PSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVR 1414
P Q T L P +VY+FR+ AQ + G GE++ L V T+ + P+ P ++
Sbjct: 493 PGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPA-PNLRAYAAS 551
Query: 1415 ARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKF 1474
S+ ++WE G ++ Y + E + + V ++ S+ ++ LK +T Y F
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKLYYMEKGTDK----EQDVDVSSHSYTINGLKKYTEYSF 607
Query: 1475 RVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGIL 1534
RV A N G S ++ TL P AP LS+ + S++I WQPPA NG +
Sbjct: 608 RVVAYNKHGPG-VSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQI 666
Query: 1535 LGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRR 1594
G++IRYR+ A S + +S L+Q ++ L++
Sbjct: 667 TGYKIRYRK---------------------ASRKSDVTETLVSGTQLSQL-IEGLDRGTE 704
Query: 1595 YEIRMSVYNAVGEGPSSP--PQEVFVGEAVPTAAPR--NVVVHGATATQLDVTWEPPPLD 1650
Y R++ G GP++ E F + T P + + T + V+W PP +
Sbjct: 705 YNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPP--E 762
Query: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDG- 1709
+QN ++GY I + T +V + ++NL + Y++++ AFN G+G
Sbjct: 763 NQNIVVRGYAIGYGIGSPHAQTIKVD---YKQRYYTIENLDPSSHYVITLKAFNNVGEGI 819
Query: 1710 --PRSTPTQGQTQQA--------AP----------SAPSSVKFSELTTTSVNVSWEAPQF 1749
S T+ T + AP P V+ S L+ ++ ++W
Sbjct: 820 PLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSL 879
Query: 1750 PNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKD------------LAEGVTY 1797
P ++ + + S+ TV K N P K K+ L Y
Sbjct: 880 PK-----HQKITD--------SRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLY 926
Query: 1798 RFRI------RAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYS--SAIAIHWSSGDP 1849
F + R+ T++ + A+ TT P V ++ + I ++W
Sbjct: 927 EFSVMVTKGRRSSTWS----MTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSE 982
Query: 1850 GKGPITRYVI-EARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGF 1908
G IT Y+I + + + D +I+ P + T + L Y F++ A N G
Sbjct: 983 ANGKITGYIIYYSTDVNAEIHDWVIE--PVVGNRLTHQIQELTLDTPYYFKIQARNSKGM 1040
Query: 1909 GTPSSPSQ 1916
G S Q
Sbjct: 1041 GPMSEAVQ 1048
Score = 114 bits (285), Expect = 1e-24
Identities = 158/648 (24%), Positives = 251/648 (38%), Gaps = 75/648 (11%)
Query: 1201 SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRS 1260
S P +V A ++ + + W P +D +G L Y V Y K+ + R
Sbjct: 440 SAPRDVVASLVSTRFIKLTW-RTPASDPHGDNLTYSVFYT-KEGIARERVENTSHPGEMQ 497
Query: 1261 AQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD-DVPGPPMGILFPEVRTTSVRL 1319
+ L +Y +V+A + G G S P +E + +PGP + TS+ +
Sbjct: 498 VTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITV 557
Query: 1320 IWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
W+ P + NG I Y++ + + T V+V S+ YT GLK + Y FR+ A
Sbjct: 558 TWETPVSGNGEIQNYKLYY-MEKGTDKEQDVDV---SSHSYTINGLKKYTEYSFRVVAYN 613
Query: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVR-ARSVLLSWEPGSDGLS--PVRYYT 1436
+ G G + + V T P + P +VR ++S+++ W+P + + Y
Sbjct: 614 KHGPGVSTPDVAVRTLS---DVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYK 670
Query: 1437 IQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKA-----TNDIGDSEFSEES 1491
I+ R+ S + + VS S +++ L T Y FRV A T D +E
Sbjct: 671 IRYRKA-SRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETF 729
Query: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG 1551
ES P E P+ L V P TS+++ W PP I ++ G+ I Y
Sbjct: 730 ESDLDETRVP-EVPSSLHVRP-LVTSIVVSWTPPENQNI--VVRGYAIGY---------- 775
Query: 1552 FTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG--- 1608
GI +P A ++ Y R Y ++NL+ Y I + +N VGEG
Sbjct: 776 ----GIGSPHAQTIKVD--YKQR--------YYTIENLDPSSHYVITLKAFNNVGEGIPL 821
Query: 1609 -------PSSPPQEVF----------VGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDS 1651
P + EV V + P P V + + +TW L
Sbjct: 822 YESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPK 881
Query: 1652 -QNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
Q Y W+ T + K S + L T Y SV
Sbjct: 882 HQKITDSRYYTVRWKTNIPANT-KYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSST 940
Query: 1711 RSTPTQGQTQQAAPSAPS---SVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPV 1767
S G T + P++P +V E ++ V+W+ P NG + GY ++Y
Sbjct: 941 WSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGY-IIYYSTDVN 999
Query: 1768 DGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT-YGPEIEA 1814
+ V V GN L ++++L Y F+I+A+ GP EA
Sbjct: 1000 AEIHDWVIEPVVGNR-LTHQIQELTLDTPYYFKIQARNSKGMGPMSEA 1046
Score = 59.3 bits (142), Expect = 4e-08
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 13/198 (6%)
Query: 1724 PSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSP 1783
PSAP V S ++T + ++W P G L Y +G+++ +
Sbjct: 439 PSAPRDVVASLVSTRFIKLTWRTPASDP---HGDNLTYSVFYTKEGIARERVENTSHPGE 495
Query: 1784 LWLKVKDLAEGVTYRFRIRAKTFTYGPEIEA--NVTTGPGEGAPGP-PGVPIIVRYSSAI 1840
+ + +++L Y FR+ A+ E A V T P PGP P + ++I
Sbjct: 496 MQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSI 555
Query: 1841 AIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV 1900
+ W + G G I Y + K+ +VSS++++++ LK Y FRV
Sbjct: 556 TVTWETPVSGNGEIQNYKLYYMEKGTD------KEQDVDVSSHSYTINGLKKYTEYSFRV 609
Query: 1901 IAVNDYGFGTPSSPSQSV 1918
+A N +G G S+P +V
Sbjct: 610 VAYNKHGPGV-STPDVAV 626
Score = 55.8 bits (133), Expect = 4e-07
Identities = 46/172 (26%), Positives = 68/172 (39%), Gaps = 9/172 (5%)
Query: 37 VHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYM-------ITSLDRTHAGFY 89
V + G +VL C+A G KW+ N L S E + I+ + AG Y
Sbjct: 259 VRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTY 318
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFR 149
CI N ++ Q E+ V F + + +H ++ + P P V W +
Sbjct: 319 FCIADNG-NETIEAQAELTVQAQPEFLK-QPTNIYAHESMDIVFECEVTGKPTPTVKWVK 376
Query: 150 DGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITL 201
+G + PS I E+ L +L V D G Y A ND +Q I L
Sbjct: 377 NGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIIL 428
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 241 bits (614), Expect = 7e-63
Identities = 189/676 (27%), Positives = 307/676 (45%), Gaps = 37/676 (5%)
Query: 322 MEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFR-QRNDGGLQISGLVPDDTGMFQC 380
ME+ V C+A G P P+ W K+ + LTR R Q G L I+ + D GM+QC
Sbjct: 1 MEENVFWECKANGRPKPTYKWLKNGEPL----LTRDRIQIEQGTLNITIVNLSDAGMYQC 56
Query: 381 FARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID--GMSVVLACETSGAPRPAITWQKG 438
A N G + ++ L+V ++ P+ +R L + G VV+ C+ +P+P TW+KG
Sbjct: 57 LAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKG 116
Query: 439 ERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRI 498
IL R T E G+L I SDAG+YTC+ATN G ++ +LVV TR+
Sbjct: 117 RDILKENE----RITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRV 172
Query: 499 TKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL-----GTESHPRIRLDRNGS 553
PP V G + C VTHD + I + W +G + G D G
Sbjct: 173 MVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGD 232
Query: 554 LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWT 613
L I G Y C V ++ S +A L VR P PE T+ + L+W
Sbjct: 233 LMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPE--AVTIDEITDTTAQLSWR 290
Query: 614 KPFDGNSPLIRYILE-MSENNAPW---TVLLASVDPKATSVTVKGLVPARSYQFRLCAVN 669
D +SP+ Y+++ + + W + + +D K + TV GL P Y+FR A N
Sbjct: 291 PGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAAN 350
Query: 670 DVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIR 729
+G G+ S+ +E+ E P P NV G + ++I W+ PE QNG GY++
Sbjct: 351 VIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVA 410
Query: 730 YCLAGLPVGYQFKNITDADVNNLLL--EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTL 787
+ G + + + AD + + E + ++ +E++V +N+ G G +S ++
Sbjct: 411 FRPYGKMI-WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSA 469
Query: 788 QGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARP 847
+ PT PP ++ A + ++T I W +P + G QGY++ W E +EE
Sbjct: 470 EEEPTKPPASIFARSLSATDIEVFWASPLEK-NRGRIQGYEVKYWRHEDKEENARKIRTV 528
Query: 848 NFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEI 906
Q S ++ LK Y +V + + G GP S V T + P P G++ ++
Sbjct: 529 GNQTSTK---ITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS- 584
Query: 907 LDTSLKVSWQEPG--EKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTY 964
D+ + ++W + + + GY++ + +NR ++ ++E L Y
Sbjct: 585 SDSKIILNWDQVKALDNESEVKGYKVLY-RWNRQSSTSVIETNKTSVE---LSLPFDEDY 640
Query: 965 TIEVAAMTSKGQGQVS 980
IE+ + G G S
Sbjct: 641 IIEIKPFSDGGDGSSS 656
Score = 141 bits (356), Expect = 6e-33
Identities = 106/381 (27%), Positives = 171/381 (44%), Gaps = 32/381 (8%)
Query: 1386 AAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSG 1445
AA L+V R P PP + +++ + LSW PG D SP+ Y IQ R S
Sbjct: 259 AAADLIV----RGPPGPPEAVTI--DEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSV 312
Query: 1446 RWALHSAS---VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
W S + + V L P+ Y+FR A N IG E S SE T +A P+
Sbjct: 313 GWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPE 372
Query: 1503 EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGA 1562
P +S + + ++I W+ E+ NG G+ + +R G + L + + A
Sbjct: 373 VTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPY---GKMIWMLTVLASADA 429
Query: 1563 TWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV 1622
S Y RN ++++ +E+++ V+N GEGP SP V+ E
Sbjct: 430 ------SRYVFRN-----------ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEE 472
Query: 1623 PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
PT P ++ +AT ++V W PL+ G IQGY++ +W + R +
Sbjct: 473 PTKPPASIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQ 531
Query: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
S K+ NL G Y ++V A+N+AG GP S T++ PS P + + + +
Sbjct: 532 TSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIIL 591
Query: 1743 SWEAPQFPNGILE--GYRLVY 1761
+W+ + + E GY+++Y
Sbjct: 592 NWDQVKALDNESEVKGYKVLY 612
Score = 130 bits (326), Expect = 2e-29
Identities = 108/384 (28%), Positives = 179/384 (46%), Gaps = 28/384 (7%)
Query: 993 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV-VGEGEEWLLIHQLSNEP 1051
PGPP + I I + L +RPG D + I+ ++++A+ VG W + +
Sbjct: 269 PGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVG----WQAVSTVPELI 324
Query: 1052 DARSME--VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
D ++ V LNP+ Y FR N++G PS+PS K +T +A P++ PANVS S
Sbjct: 325 DGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGS 384
Query: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVV----QDRVERDYTIEDL 1165
++ L + W +PE NG GY + + +GK + + D + E +
Sbjct: 385 KSELVITWETVPEELQNG--RGFGYVVAFR---PYGKMIWMLTVLASADASRYVFRNESV 439
Query: 1166 EEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPE 1225
++ + V+V FN G GP+S T V + E P+ P ++ A + +++ + V W+ E
Sbjct: 440 HPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLE 499
Query: 1226 ADRNGLVLGYKVMY-KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGD 1284
+R G + GY+V Y + +D + R GN + S ++T L VLY + V A+ G
Sbjct: 500 KNR-GRIQGYEVKYWRHEDKEENARKIRTVGNQT-STKITNLKGSVLYHLAVKAYNSAGT 557
Query: 1285 GSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIW-QPPAAPN-GIILAYQITHRLNT 1342
G PS + T P P G + + + L W Q A N + Y++ +R N
Sbjct: 558 G-PSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNR 616
Query: 1343 TTA------NTATVEVLAPSARQY 1360
++ N +VE+ P Y
Sbjct: 617 QSSTSVIETNKTSVELSLPFDEDY 640
Score = 101 bits (252), Expect = 7e-21
Identities = 98/404 (24%), Positives = 163/404 (40%), Gaps = 22/404 (5%)
Query: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
P P V++ ++T+ L W P P+ N +P ++ Y I+ G V +
Sbjct: 268 PPGPPEAVTIDEITDTTAQLSWRPGPD---NHSPITM-YVIQARTPFSVGWQAVSTVPEL 323
Query: 1156 VERDY---TIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALAT 1211
++ T+ L W EY + A N IG G P + RT E++P P NVS
Sbjct: 324 IDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGG 383
Query: 1212 TSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYV 1270
+ S +++ W VPE +NG GY V ++ L ++SR + + +
Sbjct: 384 SKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFS 443
Query: 1271 LYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPN-G 1329
+EV+V F G+G S ++ ++ PP I + T + + W P N G
Sbjct: 444 PFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRG 503
Query: 1330 IILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA 1389
I Y++ + + A + T LK +Y + A G G ++
Sbjct: 504 RIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSAT 563
Query: 1390 LVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPSGRW 1447
+ VTT K QPP + D + ++L+W+ D S V+ Y + RW
Sbjct: 564 VNVTTRKPPPSQPPGNIIWNSSDSK---IILNWDQVKALDNESEVKGYKVLY------RW 614
Query: 1448 ALHSASVSHNASSFIVDRLKPF-TSYKFRVKATNDIGDSEFSEE 1490
S++ + V+ PF Y +K +D GD SE+
Sbjct: 615 NRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQ 658
Score = 63.2 bits (152), Expect = 3e-09
Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 1823 GAPGPPGVPIIVRYSSAIA-IHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
G PGPP I + A + W G PIT YVI+AR W + +P+ +
Sbjct: 267 GPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQA-VSTVPELID 325
Query: 1882 SYTFSMDI--LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
TF+ + L P V Y+FR +A N G G PS PS+ ++A P
Sbjct: 326 GKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALP 371
Score = 61.2 bits (147), Expect = 1e-08
Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 38/307 (12%)
Query: 48 CMAEGSWPLEFKWLHNNRELT---KFSLEYRYM-ITSLDRTHAGFYRCIVRNRMGALLQR 103
C A G +KWL N L + +E + IT ++ + AG Y+C+ N+ G +
Sbjct: 9 CKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSN 68
Query: 104 QTEVQVAYMGSFEEG--EKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIA 161
+A F ++ V G VI AS P+P TW + + + RI
Sbjct: 69 AELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKAS-PKPVYTWKKGRDILKENERIT 127
Query: 162 ITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPP 221
I+ + L I++ DAG Y A N + T + DP +++PP
Sbjct: 128 ISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV---------KDP--TRVMVPP 176
Query: 222 KNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLS-GGISDHNRR---------LTI 271
+ V G S + L C + + W +G L+ DH R L I
Sbjct: 177 SSMDVTVGES-IVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMI 235
Query: 272 PNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQ 331
N AG Y C + +SV + A L V PP P +T ++++ D Q
Sbjct: 236 RNIQLKHAGKYVC---MVQTSVDRLSAAADLIVRGPP----GPPEAVT--IDEITDTTAQ 286
Query: 332 AKGVPPP 338
P P
Sbjct: 287 LSWRPGP 293
Score = 61.2 bits (147), Expect = 1e-08
Identities = 90/450 (20%), Positives = 168/450 (37%), Gaps = 39/450 (8%)
Query: 791 PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 850
P PP V + TT + +W P P + I Y + A P + T
Sbjct: 268 PPGPPEAVTIDEITDTTAQLSWR-PGPDNHSPITM-YVIQARTPFSVGWQAVSTVPELID 325
Query: 851 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTP-QLVRTHEDVPGPV-GHLSFSEILD 908
V GL + EY + G G S P + RT E +P ++S
Sbjct: 326 GKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSK 385
Query: 909 TSLKVSWQEPGEK--NGILTGYRISWEEYNRTNTRVTHYLPNVTLEY--RVTGLTALTTY 964
+ L ++W+ E+ NG GY +++ Y + +T Y R + + +
Sbjct: 386 SELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPF 445
Query: 965 TIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV------TLQFRPGYD 1018
++V +KG+G S +T+ E PP ++ ++ + L+ G
Sbjct: 446 EVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRI 505
Query: 1019 GKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVG 1078
+ W E + E I + N+ S ++ +L Y ++ N G
Sbjct: 506 QGYEVKYWRHE------DKEENARKIRTVGNQ---TSTKITNLKGSVLYHLAVKAYNSAG 556
Query: 1079 TSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKY 1138
T PS + + T + PP P N+ + +S++ + L W + ++ E GYK+ Y
Sbjct: 557 TG-PSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALD--NESEVKGYKVLY 612
Query: 1139 SRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTV-------V 1191
+ ++ + VE ++ +Y ++++ F+ G G S+ +
Sbjct: 613 RWNRQSSTSVIETNKTSVELSLPFDE-----DYIIEIKPFSDGGDGSSSEQIRIPKISNA 667
Query: 1192 GRTRESVPSSGPTNVSALATTSSSMLVRWS 1221
+S +SA++T S+ R S
Sbjct: 668 YARGSGASTSNACTLSAISTIMISLTARSS 697
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 240 bits (612), Expect = 1e-62
Identities = 245/1015 (24%), Positives = 399/1015 (39%), Gaps = 88/1015 (8%)
Query: 42 NRLVLTCMAEGSWPLEFKWLHNNRELT-----KFSLEYRYMITSLD-------RTHAGFY 89
+ +++ C A+G+ F W N+R + S+ R +D + G Y
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWF 148
+C RN+ G L + +QV+ + +E V G ++ P P + W
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWM 170
Query: 149 RDGRK-IPPSSRIAITLENTLVILSTVAPD--------AGRYYVQAVNDKNGDNKTSQPI 199
+ I R++ L + + D A ++ + KN P
Sbjct: 171 SSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKN-------PF 223
Query: 200 TLTV-----------------ENVGGPADPIAPTIIIPPKNTS--VVAGTSEVTLECVAN 240
TL V + G A+ P+ + P S +V ++ LEC+A+
Sbjct: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAER-TPSFMYPQGTASSQMVLRGMDLLLECIAS 282
Query: 241 ARPLIKLHIIW-KKDGVLLS--GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVV 297
P I W KK G L S + N+ L I N + D+G Y C L S+ + S+
Sbjct: 283 GVPTPD--IAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFC---LASNKMGSIR 337
Query: 298 RGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRF 357
+ V P ++ EP+ I A E + C+A G P P++ W + ++
Sbjct: 338 HTISVRVKAAPYWLDEPKNLILAPGEDG-RLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 396
Query: 358 RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT--RGPLDSTVID 415
R+ + ++QC N G + + +++V + P + R L ++
Sbjct: 397 REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 456
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
+ L C G+P P + W K + ++ + E+GSL I D G YTC
Sbjct: 457 NRTR-LDCPFFGSPIPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 512
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 535
+ATN G E L V TRI + P+DQ +GT + C V HDP + + W KD
Sbjct: 513 VATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD 572
Query: 536 ATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEH 595
L + + + SL I D G+YTC + D A+L V P P
Sbjct: 573 EPLYIGNRMK---KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRD 629
Query: 596 PVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENN-APWTVLLASVDPKATSVTVKG 654
L+ + R++ LTW NSP+ Y+++ E+ P S P + + V
Sbjct: 630 --LELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLR 687
Query: 655 LVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPP 714
L P +YQFR+ A+N+VG S +ER PP + P +V G ++ I W P
Sbjct: 688 LSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPM 747
Query: 715 PESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAG 774
+ G YI+++ + N+T + ++ ++ YEI V A N G
Sbjct: 748 NATSAFGPNLRYIVKW--RRRETREAWNNVT-VWGSRYVVGQTPVYVPYEIRVQAENDFG 804
Query: 775 LGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEP 834
G V ++ + P P V NST I WN + G + Y+ W
Sbjct: 805 KGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRE 864
Query: 835 E---QEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH 891
+ V+ + +F G VS L ++ Y ++ GDGPRS + T
Sbjct: 865 SSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP 924
Query: 892 EDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTR---VTHYLPN 948
E VP + ++ + W P NGI+ GY + + +N T V ++ PN
Sbjct: 925 EGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPN 984
Query: 949 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISN 1003
T ++ V ++ Y ++A T G G+ V E P PP +N
Sbjct: 985 QT-KFTVQRTDPVSRYRFTLSARTQVGSGE--------AVTEESPAPPNEAYTNN 1030
Score = 140 bits (352), Expect = 2e-32
Identities = 109/420 (25%), Positives = 188/420 (44%), Gaps = 27/420 (6%)
Query: 993 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
P P +L ++++ RSV L + PG + I+ ++V+ + G W H S P
Sbjct: 624 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGV-W---HDHSKYPG 679
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS 1112
+ + V L+P+ Y FR+ +N VG+S PS PS + +T APP+ P +V + +
Sbjct: 680 SVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 739
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYR 1172
+ + W P+ G ++ Y +K+ R + + V Y + + Y
Sbjct: 740 MEITWTPMNATSAFG--PNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPVYVPYE 794
Query: 1173 VQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLV 1232
++VQA N G GP ++V+G + E P + PT V S+++ ++W+ V G +
Sbjct: 795 IRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQL 854
Query: 1233 LGYKVMYKEKDSDTQPRFWLVEGNSSRS-------AQLTGLGKYVLYEVQVLAFTRIGDG 1285
Y+ Y ++S W+ + S ++ L Y Y+++++ GDG
Sbjct: 855 REYRAYY-WRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG 913
Query: 1286 SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH-RLNTTT 1344
S T + VP P + ++ L W P PNGI++ Y + + N T
Sbjct: 914 PRSETKEF-TTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTK 972
Query: 1345 ANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPS 1404
VE +P+ ++T P S Y F ++A+T+ G GEA VT E P PP+
Sbjct: 973 VGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA-----VTEES---PAPPN 1024
Score = 138 bits (347), Expect = 7e-32
Identities = 120/459 (26%), Positives = 190/459 (41%), Gaps = 62/459 (13%)
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRE--L 1442
+ A+A + + DRP+ ++ D+ RSV L+W PG SP+ Y +Q E
Sbjct: 612 DLAKAYLTVLGRPDRPRD-----LELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQF 666
Query: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
G W HS S+ + RL P+ +Y+FRV A N++G S S SE T A P+
Sbjct: 667 QPGVWHDHSKYPGSVNSAVL--RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPE 724
Query: 1503 EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGA 1562
P + ++ I W P G L + +++R R T NN
Sbjct: 725 SNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR-------RRETREAWNNV-T 776
Query: 1563 TWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV 1622
W ++Y + + YEIR+ N G+GP + GE
Sbjct: 777 VWG----------------SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDY 820
Query: 1623 PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
P AAP V V +T + + W D+ G ++ Y+ Y+W + +K L++++
Sbjct: 821 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRE-----SSLLKNLWVSQ 875
Query: 1683 NSVK-----------LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVK 1731
+ + L Y+ Y + + N GDGPRS + T + PSAP +
Sbjct: 876 KRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFR 935
Query: 1732 FSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLK--VK 1789
+ ++N+ W+ P+ PNGI+ GY L Y + +K+ V+ SP K V+
Sbjct: 936 VRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNG----TKVGKQIVENFSPNQTKFTVQ 991
Query: 1790 DLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPP 1828
YRF + A+T E E +P PP
Sbjct: 992 RTDPVSRYRFTLSARTQVGSGEAVT-------EESPAPP 1023
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/334 (23%), Positives = 127/334 (38%), Gaps = 47/334 (14%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
+ + +PP K+ + + + I C+AKG P PS W +++ + K R R
Sbjct: 29 MDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRR 88
Query: 362 DGGLQI----SGLVPDD-TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI-D 415
G + SG P++ G +QCFARN G ++ S +P + LD V+ +
Sbjct: 89 RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQE 148
Query: 416 GMSVVLACE-TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGT-Y 473
G + L C G P P I W Q R + +G L S + D T Y
Sbjct: 149 GAPLTLQCNPPPGLPSPVIFWMSSS---MEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 205
Query: 474 TCLA--------------------------TNSRGVDEASADLVVWARTRITKPPQ---- 503
+C A ++ R + + V RT PQ
Sbjct: 206 SCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTAS 265
Query: 504 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSG 562
Q V++G + C + P I W K G L ++ + + + N +L I+
Sbjct: 266 SQMVLRGMDLLLECIASGVPTPDI--AWYKKGGDLPSD---KAKFENFNKALRITNVSEE 320
Query: 563 DIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHP 596
D G Y C + G+ + +RV+ P+ + P
Sbjct: 321 DSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
Score = 64.7 bits (156), Expect = 9e-10
Identities = 82/375 (21%), Positives = 136/375 (36%), Gaps = 32/375 (8%)
Query: 35 TQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYM-----ITSLDRTHAGFY 89
+Q+ L G L+L C+A G + W +L ++ IT++ +G Y
Sbjct: 266 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEY 325
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFR 149
C+ N+MG+ ++ V+V + + K+ ++ GE + R P+P V W
Sbjct: 326 FCLASNKMGS-IRHTISVRVKAAPYWLDEPKNLILAPGEDGRL-VCRANGNPKPTVQWMV 383
Query: 150 DGRKI---PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENV 206
+G + PP+ + +T++ T Y N+ + N
Sbjct: 384 NGEPLQSAPPNPNREVA-GDTIIFRDTQISSRAVYQCNTSNEHG----------YLLANA 432
Query: 207 GGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISD-- 264
+ P ++ P V + L+C P+ L G L GG
Sbjct: 433 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 492
Query: 265 HNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEK 324
N L I D G Y C A + VR L V +P + + PE + A
Sbjct: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR---LEVKDPTRIYRMPEDQV-ARRGT 548
Query: 325 VVDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFA 382
V + C+ K P +T W KD + + + + D L I G+ D G + C A
Sbjct: 549 TVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---KEDDSLTIFGVAERDQGSYTCVA 605
Query: 383 RNAAGEVQTSTYLAV 397
+ YL V
Sbjct: 606 STELDQDLAKAYLTV 620
Score = 49.3 bits (116), Expect = 4e-05
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 1839 AIAIHWSSGDPGKGPITRYVIEARPSD--EGLWDILIKDIPKEVSSYTFSMDILKPGVSY 1896
++ + W GD PIT YV++ G+W D K S ++ L P V+Y
Sbjct: 639 SVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWH----DHSKYPGSVNSAVLRLSPYVNY 694
Query: 1897 DFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
FRVIA+N+ G PS PS+ A P
Sbjct: 695 QFRVIAINEVGSSHPSLPSERYRTSGAPP 723
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 239 bits (611), Expect = 2e-62
Identities = 245/1007 (24%), Positives = 398/1007 (39%), Gaps = 82/1007 (8%)
Query: 42 NRLVLTCMAEGSWPLEFKWLHNNRELT-----KFSLEYRYMITSLD-------RTHAGFY 89
+ +++ C A+G+ F W N+R + S+ R +D + G Y
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWF 148
+C RN+ G L + +QV+ + +E V G ++ P P + W
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWM 170
Query: 149 RDGRK-IPPSSRIAITLENTLVILSTVAPD--------AGRYYVQAVNDKNGDNKTSQPI 199
+ I R++ L + + D A ++ + KN P
Sbjct: 171 SSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKN-------PF 223
Query: 200 TLTV-----------------ENVGGPADPIAPTIIIPPKNTS--VVAGTSEVTLECVAN 240
TL V + G A+ P+ + P S +V ++ LEC+A+
Sbjct: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAER-TPSFMYPQGTASSQMVLRGMDLLLECIAS 282
Query: 241 ARPLIKLHIIW-KKDGVLLS--GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVV 297
P I W KK G L S + N+ L I N + D+G Y C L S+ + S+
Sbjct: 283 GVPTPD--IAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFC---LASNKMGSIR 337
Query: 298 RGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRF 357
+ V P ++ EP+ I A E + C+A G P P++ W + ++
Sbjct: 338 HTISVRVKAAPYWLDEPKNLILAPGEDG-RLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 396
Query: 358 RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT--RGPLDSTVID 415
R+ + ++QC N G + + +++V + P + R L ++
Sbjct: 397 REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 456
Query: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
+ L C G+P P + W K + ++ + E+GSL I D G YTC
Sbjct: 457 NRTR-LDCPFFGSPIPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 512
Query: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 535
+ATN G E L V TRI + P+DQ +GT + C V HDP + + W KD
Sbjct: 513 VATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD 572
Query: 536 ATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEH 595
L + + + SL I D G+YTC + D A+L V P P
Sbjct: 573 EPLYIGNRMK---KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRD 629
Query: 596 PVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENN-APWTVLLASVDPKATSVTVKG 654
L+ + R++ LTW NSP+ Y+++ E+ P S P + + V
Sbjct: 630 --LELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLR 687
Query: 655 LVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPP 714
L P +YQFR+ A+N+VG S +ER PP + P +V G ++ I W P
Sbjct: 688 LSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPM 747
Query: 715 PESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAG 774
+ G YI+++ + N+T + ++ ++ YEI V A N G
Sbjct: 748 NATSAFGPNLRYIVKW--RRRETREAWNNVT-VWGSRYVVGQTPVYVPYEIRVQAENDFG 804
Query: 775 LGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEP 834
G V ++ + P P V NST I WN + G + Y+ W
Sbjct: 805 KGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRE 864
Query: 835 E---QEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH 891
+ V+ + +F G VS L ++ Y ++ GDGPRS + T
Sbjct: 865 SSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP 924
Query: 892 EDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTR---VTHYLPN 948
E VP + ++ + W P NGI+ GY + + +N T V ++ PN
Sbjct: 925 EGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPN 984
Query: 949 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGP 995
T ++ V ++ Y ++A T G G+ A T S PP P
Sbjct: 985 QT-KFTVQRTDPVSRYRFTLSARTQVGSGE--AVTEESPAPPNEATP 1028
Score = 140 bits (352), Expect = 2e-32
Identities = 109/420 (25%), Positives = 188/420 (44%), Gaps = 27/420 (6%)
Query: 993 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD 1052
P P +L ++++ RSV L + PG + I+ ++V+ + G W H S P
Sbjct: 624 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGV-W---HDHSKYPG 679
Query: 1053 ARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS 1112
+ + V L+P+ Y FR+ +N VG+S PS PS + +T APP+ P +V + +
Sbjct: 680 SVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 739
Query: 1113 LWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYR 1172
+ + W P+ G ++ Y +K+ R + + V Y + + Y
Sbjct: 740 MEITWTPMNATSAFG--PNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPVYVPYE 794
Query: 1173 VQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLV 1232
++VQA N G GP ++V+G + E P + PT V S+++ ++W+ V G +
Sbjct: 795 IRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQL 854
Query: 1233 LGYKVMYKEKDSDTQPRFWLVEGNSSRS-------AQLTGLGKYVLYEVQVLAFTRIGDG 1285
Y+ Y ++S W+ + S ++ L Y Y+++++ GDG
Sbjct: 855 REYRAYY-WRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG 913
Query: 1286 SPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH-RLNTTT 1344
S T + VP P + ++ L W P PNGI++ Y + + N T
Sbjct: 914 PRSETKEF-TTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTK 972
Query: 1345 ANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPS 1404
VE +P+ ++T P S Y F ++A+T+ G GEA VT E P PP+
Sbjct: 973 VGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA-----VTEES---PAPPN 1024
Score = 138 bits (348), Expect = 5e-32
Identities = 119/457 (26%), Positives = 189/457 (41%), Gaps = 56/457 (12%)
Query: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRE--L 1442
+ A+A + + DRP+ ++ D+ RSV L+W PG SP+ Y +Q E
Sbjct: 612 DLAKAYLTVLGRPDRPRD-----LELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQF 666
Query: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
G W HS S+ + RL P+ +Y+FRV A N++G S S SE T A P+
Sbjct: 667 QPGVWHDHSKYPGSVNSAVL--RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPE 724
Query: 1503 EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGA 1562
P + ++ I W P G L + +++R R T NN
Sbjct: 725 SNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR-------RRETREAWNNV-T 776
Query: 1563 TWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV 1622
W ++Y + + YEIR+ N G+GP + GE
Sbjct: 777 VWG----------------SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDY 820
Query: 1623 PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
P AAP V V +T + + W D+ G ++ Y+ Y+W + +K L++++
Sbjct: 821 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRE-----SSLLKNLWVSQ 875
Query: 1683 NSVK-----------LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVK 1731
+ + L Y+ Y + + N GDGPRS + T + PSAP +
Sbjct: 876 KRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFR 935
Query: 1732 FSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLK--VK 1789
+ ++N+ W+ P+ PNGI+ GY L Y + +K+ V+ SP K V+
Sbjct: 936 VRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNG----TKVGKQIVENFSPNQTKFTVQ 991
Query: 1790 DLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAP 1825
YRF + A+T G + P E P
Sbjct: 992 RTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATP 1028
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/334 (23%), Positives = 127/334 (38%), Gaps = 47/334 (14%)
Query: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
+ + +PP K+ + + + I C+AKG P PS W +++ + K R R
Sbjct: 29 MDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRR 88
Query: 362 DGGLQI----SGLVPDD-TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI-D 415
G + SG P++ G +QCFARN G ++ S +P + LD V+ +
Sbjct: 89 RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQE 148
Query: 416 GMSVVLACE-TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGT-Y 473
G + L C G P P I W Q R + +G L S + D T Y
Sbjct: 149 GAPLTLQCNPPPGLPSPVIFWMSSS---MEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 205
Query: 474 TCLA--------------------------TNSRGVDEASADLVVWARTRITKPPQ---- 503
+C A ++ R + + V RT PQ
Sbjct: 206 SCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTAS 265
Query: 504 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSG 562
Q V++G + C + P I W K G L ++ + + + N +L I+
Sbjct: 266 SQMVLRGMDLLLECIASGVPTPDI--AWYKKGGDLPSD---KAKFENFNKALRITNVSEE 320
Query: 563 DIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHP 596
D G Y C + G+ + +RV+ P+ + P
Sbjct: 321 DSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
Score = 64.7 bits (156), Expect = 9e-10
Identities = 82/375 (21%), Positives = 136/375 (36%), Gaps = 32/375 (8%)
Query: 35 TQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYM-----ITSLDRTHAGFY 89
+Q+ L G L+L C+A G + W +L ++ IT++ +G Y
Sbjct: 266 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEY 325
Query: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFR 149
C+ N+MG+ ++ V+V + + K+ ++ GE + R P+P V W
Sbjct: 326 FCLASNKMGS-IRHTISVRVKAAPYWLDEPKNLILAPGEDGRL-VCRANGNPKPTVQWMV 383
Query: 150 DGRKI---PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENV 206
+G + PP+ + +T++ T Y N+ + N
Sbjct: 384 NGEPLQSAPPNPNREVA-GDTIIFRDTQISSRAVYQCNTSNEHG----------YLLANA 432
Query: 207 GGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISD-- 264
+ P ++ P V + L+C P+ L G L GG
Sbjct: 433 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 492
Query: 265 HNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEK 324
N L I D G Y C A + VR L V +P + + PE + A
Sbjct: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR---LEVKDPTRIYRMPEDQV-ARRGT 548
Query: 325 VVDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFA 382
V + C+ K P +T W KD + + + + D L I G+ D G + C A
Sbjct: 549 TVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---KEDDSLTIFGVAERDQGSYTCVA 605
Query: 383 RNAAGEVQTSTYLAV 397
+ YL V
Sbjct: 606 STELDQDLAKAYLTV 620
Score = 58.9 bits (141), Expect = 5e-08
Identities = 90/427 (21%), Positives = 163/427 (38%), Gaps = 23/427 (5%)
Query: 1091 TLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSH 1150
T+ PD P ++ L +E S+ L W+P + N +P + Y +++
Sbjct: 619 TVLGRPDR-PRDLELTDLAERSVRLTWIP---GDANNSPIT-DYVVQFEEDQFQPGVWHD 673
Query: 1151 VVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSAL 1209
+ + + L + Y+ +V A N +GS P + RT + P S P +V
Sbjct: 674 HSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGE 733
Query: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKY 1269
T ++M + W+ + G L Y V ++ +++ V G+ Q Y
Sbjct: 734 GTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTP---VY 790
Query: 1270 VLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFPEVRTTSVRLIWQPPAAPN 1328
V YE++V A G G P ++ + +D P P + + +T++ L W +
Sbjct: 791 VPYEIRVQAENDFGKG-PEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDT 849
Query: 1329 --GIILAYQITHRLNTTTANTATVEVLAPSAR------QYTATGLKPESVYLFRITAQTR 1380
G + Y+ + ++ V A + + L P S Y +
Sbjct: 850 VQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNG 909
Query: 1381 KGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTR 1440
+G G +E TT + P P R V+Q ++ ++ L W+ + YT++
Sbjct: 910 RGDGPRSETKEFTTPE-GVPSAPRRFRVRQPNLE--TINLEWDHPEHPNGIMIGYTLKYV 966
Query: 1441 ELPSGRWALHSA-SVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQA 1499
+ + S N + F V R P + Y+F + A +G E E +A
Sbjct: 967 AFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA 1026
Query: 1500 APDEAPT 1506
P A T
Sbjct: 1027 TPTAAYT 1033
Score = 49.3 bits (116), Expect = 4e-05
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 1839 AIAIHWSSGDPGKGPITRYVIEARPSD--EGLWDILIKDIPKEVSSYTFSMDILKPGVSY 1896
++ + W GD PIT YV++ G+W D K S ++ L P V+Y
Sbjct: 639 SVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWH----DHSKYPGSVNSAVLRLSPYVNY 694
Query: 1897 DFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
FRVIA+N+ G PS PS+ A P
Sbjct: 695 QFRVIAINEVGSSHPSLPSERYRTSGAPP 723
Score = 38.5 bits (88), Expect = 0.073
Identities = 30/107 (28%), Positives = 42/107 (39%), Gaps = 10/107 (9%)
Query: 608 INLTWTKPFDGNSPLIRYILEMSENNAPWT--VLLASVDPKATSVTVKGLVPARSYQFRL 665
INL W P N +I Y L+ N ++ + P T TV+ P Y+F L
Sbjct: 944 INLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTL 1003
Query: 666 CAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQ 712
A VG G+ ++ EE P P + + TN I Q
Sbjct: 1004 SARTQVGSGE--------AVTEESPAPPNEATPTAAYTNNQADIATQ 1042
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,748,005
Number of Sequences: 37866
Number of extensions: 4714925
Number of successful extensions: 31798
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 266
Number of HSP's successfully gapped in prelim test: 323
Number of HSP's that attempted gapping in prelim test: 14858
Number of HSP's gapped (non-prelim): 6021
length of query: 2172
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2054
effective length of database: 13,779,330
effective search space: 28302743820
effective search space used: 28302743820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.