BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|22218619 WD repeat domain 40A [Homo sapiens] (453 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|22218619 WD repeat domain 40A [Homo sapiens] 939 0.0 gi|61966713 DDB1 and CUL4 associated factor 12-like 2 [Homo sapi... 590 e-169 gi|71284432 WD repeat domain 40B [Homo sapiens] 555 e-158 gi|19913367 transducin beta-like 1Y [Homo sapiens] 42 9e-04 gi|19913365 transducin beta-like 1Y [Homo sapiens] 42 9e-04 gi|15150805 transducin beta-like 1Y [Homo sapiens] 42 9e-04 gi|21536371 telomerase-associated protein 1 [Homo sapiens] 42 0.001 gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 41 0.003 gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 40 0.006 gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 40 0.006 gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 40 0.006 gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 40 0.006 gi|75709220 cleavage stimulation factor subunit 1 [Homo sapiens] 37 0.028 gi|4557491 cleavage stimulation factor subunit 1 [Homo sapiens] 37 0.028 gi|75709217 cleavage stimulation factor subunit 1 [Homo sapiens] 37 0.028 gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 36 0.082 gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 36 0.082 gi|17402902 guanine nucleotide binding protein beta-subunit-like... 34 0.24 gi|41281564 WD repeat domain 37 [Homo sapiens] 34 0.24 gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 34 0.31 gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 34 0.31 gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 34 0.31 gi|16554629 WD repeat domain 5 [Homo sapiens] 34 0.31 gi|16554627 WD repeat domain 5 [Homo sapiens] 34 0.31 gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 33 0.41 gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 33 0.69 gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 33 0.69 gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 33 0.69 gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 32 0.91 gi|5174447 guanine nucleotide binding protein (G protein), beta ... 32 0.91 >gi|22218619 WD repeat domain 40A [Homo sapiens] Length = 453 Score = 939 bits (2428), Expect = 0.0 Identities = 453/453 (100%), Positives = 453/453 (100%) Query: 1 MARKVVSRKRKAPASPGAGSDAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREVRLQNE 60 MARKVVSRKRKAPASPGAGSDAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREVRLQNE Sbjct: 1 MARKVVSRKRKAPASPGAGSDAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREVRLQNE 60 Query: 61 TSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCNTLFVVDVQTS 120 TSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCNTLFVVDVQTS Sbjct: 61 TSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCNTLFVVDVQTS 120 Query: 121 QITKIPILKDREPGGVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD 180 QITKIPILKDREPGGVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD Sbjct: 121 QITKIPILKDREPGGVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD 180 Query: 181 DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKAL 240 DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKAL Sbjct: 181 DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKAL 240 Query: 241 KDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLSTKLPYCRENV 300 KDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLSTKLPYCRENV Sbjct: 241 KDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLSTKLPYCRENV 300 Query: 301 CLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSFYEHIITVGTGQG 360 CLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSFYEHIITVGTGQG Sbjct: 301 CLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSFYEHIITVGTGQG 360 Query: 361 SLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWRNYFSDIDFFPNA 420 SLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWRNYFSDIDFFPNA Sbjct: 361 SLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWRNYFSDIDFFPNA 420 Query: 421 VYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS 453 VYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS Sbjct: 421 VYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS 453 >gi|61966713 DDB1 and CUL4 associated factor 12-like 2 [Homo sapiens] Length = 463 Score = 590 bits (1521), Expect = e-169 Identities = 296/462 (64%), Positives = 352/462 (76%), Gaps = 21/462 (4%) Query: 7 SRKRKAPA-SPGAGS---------DAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREVR 56 SRKRKAPA GAGS D +GP L K+++ P +R LV+YLK REV Sbjct: 8 SRKRKAPAVEAGAGSSSSQGLAAADGEGPL------LPKKQKRPATRRRLVHYLKGREVG 61 Query: 57 LQNETS---YSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCNTLF 113 + + L GYA Q+LP LL ER+ LGTLNKVFASQWLN RQVVCGTKCNTLF Sbjct: 62 ARGPAGLQGFEGELRGYAVQRLPELLTERQLDLGTLNKVFASQWLNARQVVCGTKCNTLF 121 Query: 114 VVDVQTSQITKIPILKDREPG-GVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPT 172 VVDVQ+ IT+IP+++D+E G QGCGIHAIELNPS+TLLATGG+NPNSLAIY+LPT Sbjct: 122 VVDVQSGHITRIPLMRDKEAGLAQAHQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPT 181 Query: 173 LDPVCVGD-DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPV 231 LDP+C+GD GHKDWIF++AW+SDT+AVSGSRDG++ LW + D+ S A H+ +PV Sbjct: 182 LDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDMFNGSIAWHSEVGLPV 241 Query: 232 YAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLST 291 YAHI + ++ IP+ TNP N KVRALAF+ KN+ELGAVSLDGYFHLWKA +TLS+LLS Sbjct: 242 YAHIRPRDVEAIPRASTNPSNRKVRALAFSGKNQELGAVSLDGYFHLWKARSTLSRLLSI 301 Query: 292 KLPYCRENVCLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSFYEH 351 +LPYCRENVCL Y E S+YAVGSQ+HVSFLDPRQ N++ +CSRE G+G+RS+SFY+H Sbjct: 302 RLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIRPLCSREGGTGVRSLSFYQH 361 Query: 352 IITVGTGQGSLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWRNYF 411 IITVGTG GSLLFYDIRAQ+FLEER S+ S P AG LKL G+GWLN D+ W NYF Sbjct: 362 IITVGTGHGSLLFYDIRAQKFLEERASSSLDSMPGPAGRKLKLACGRGWLNQDDVWVNYF 421 Query: 412 SDIDFFPNAVYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS 453 + FPNA+YTHCY+ KLFVAGGPLPSGLHGNYAGLWS Sbjct: 422 GGMGEFPNALYTHCYNWPEMKLFVAGGPLPSGLHGNYAGLWS 463 >gi|71284432 WD repeat domain 40B [Homo sapiens] Length = 463 Score = 555 bits (1429), Expect = e-158 Identities = 285/465 (61%), Positives = 343/465 (73%), Gaps = 27/465 (5%) Query: 7 SRKRKAPA-------SPGAG---SDAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREV- 55 SRKRKAPA SP G +D +GP L KR+R P RS+ +YLK REV Sbjct: 8 SRKRKAPAVEADAESSPSQGLAAADGEGPL------LLKRQRRPATYRSMAHYLKVREVG 61 Query: 56 -----RLQNETSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCN 110 RLQ + L GYA Q+LP LL ER+ LGT+NKVFASQWLN RQVVCGTKCN Sbjct: 62 GWGPARLQG---FDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCN 118 Query: 111 TLFVVDVQTSQITKIPILKDREPG-GVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYR 169 TLFVVDV++ I +IP+L+D E QQGCGIHAIELNPS+TLLATGG+NPNSLAIY+ Sbjct: 119 TLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQ 178 Query: 170 LPTLDPVCVGD-DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSR 228 LP+LDP+C+GD GHKDWIF++AW+SDT+AVSGSRDG++ LW + D + A H+ Sbjct: 179 LPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVG 238 Query: 229 VPVYAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKL 288 +PVYAHI + ++ IP+ NP N KVRALA KN+ELGAVSLDGYFHLWKA + LS+L Sbjct: 239 LPVYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRL 298 Query: 289 LSTKLPYCRENVCLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSF 348 LS +LPY R+NVCL Y + SVYAVGS +HVSFLD RQ N++ +CSRE G+G+RS+SF Sbjct: 299 LSIRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSF 358 Query: 349 YEHIITVGTGQGSLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWR 408 Y HIITVGTGQGSLLFYD+RAQ+FLEER SA S A L+L G+GWLNH++ W Sbjct: 359 YRHIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWV 418 Query: 409 NYFSDIDFFPNAVYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS 453 NYF ++ FPNA+YTHCY+ KLFVAGGPLP+GLHGNYAGLWS Sbjct: 419 NYFGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS 463 >gi|19913367 transducin beta-like 1Y [Homo sapiens] Length = 522 Score = 42.4 bits (98), Expect = 9e-04 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 41/152 (26%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +PS LLA+ D+ +L I+ + CV D H I++I W Sbjct: 362 VNAIKWDPSGMLLASCSDDM-TLKIWSMK--QDACVHDLQAHSKEIYTIKWSPTGPATSN 418 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 S M S S D ++ LW+V V T + +H + PVY+ Sbjct: 419 PNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH---QEPVYS------------------ 457 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAEN 283 +AF+ K L + S D Y H+W ++ Sbjct: 458 ------VAFSPDGKYLASGSFDKYVHIWNTQS 483 Score = 37.4 bits (85), Expect = 0.028 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W + ++ + S V H + Sbjct: 177 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLNEN-------SNGGSTQLVLRHCIREG 228 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 D+P N V +L +N+ L S DG+ +W L+ L Sbjct: 229 GHDVPS------NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTL 272 >gi|19913365 transducin beta-like 1Y [Homo sapiens] Length = 522 Score = 42.4 bits (98), Expect = 9e-04 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 41/152 (26%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +PS LLA+ D+ +L I+ + CV D H I++I W Sbjct: 362 VNAIKWDPSGMLLASCSDDM-TLKIWSMK--QDACVHDLQAHSKEIYTIKWSPTGPATSN 418 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 S M S S D ++ LW+V V T + +H + PVY+ Sbjct: 419 PNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH---QEPVYS------------------ 457 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAEN 283 +AF+ K L + S D Y H+W ++ Sbjct: 458 ------VAFSPDGKYLASGSFDKYVHIWNTQS 483 Score = 37.4 bits (85), Expect = 0.028 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W + ++ + S V H + Sbjct: 177 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLNEN-------SNGGSTQLVLRHCIREG 228 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 D+P N V +L +N+ L S DG+ +W L+ L Sbjct: 229 GHDVPS------NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTL 272 >gi|15150805 transducin beta-like 1Y [Homo sapiens] Length = 522 Score = 42.4 bits (98), Expect = 9e-04 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 41/152 (26%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +PS LLA+ D+ +L I+ + CV D H I++I W Sbjct: 362 VNAIKWDPSGMLLASCSDDM-TLKIWSMK--QDACVHDLQAHSKEIYTIKWSPTGPATSN 418 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 S M S S D ++ LW+V V T + +H + PVY+ Sbjct: 419 PNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH---QEPVYS------------------ 457 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAEN 283 +AF+ K L + S D Y H+W ++ Sbjct: 458 ------VAFSPDGKYLASGSFDKYVHIWNTQS 483 Score = 37.4 bits (85), Expect = 0.028 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W + ++ + S V H + Sbjct: 177 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLNEN-------SNGGSTQLVLRHCIREG 228 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 D+P N V +L +N+ L S DG+ +W L+ L Sbjct: 229 GHDVPS------NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTL 272 >gi|21536371 telomerase-associated protein 1 [Homo sapiens] Length = 2627 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 155 LATGGDNPNSLAIYRLPTLDPVCVGDDG--HKDWIFSIAWISDTMAVSGSRDGSMGLWE 211 LATGG + + L PV + H+DW+ AW D + +S S DGS+GLW+ Sbjct: 2076 LATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWTKDNLLISCSSDGSVGLWD 2134 Score = 30.4 bits (67), Expect = 3.4 Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPT-LDPVCVGDDGHKDWIFSIAWISD-TMAVS 200 + A ++ + L+ T ++ S+ ++++P D C+ + ++AW D +MAVS Sbjct: 2241 VRAAAVSETSGLMLTASED-GSVRLWQVPKEADDTCIPRSSAA--VTAVAWAPDGSMAVS 2297 Query: 201 GSRDGSMGLWEVTDDVLTKSDARH 224 G++ G + LW+ V T H Sbjct: 2298 GNQAGELILWQEAKAVATAQAPGH 2321 >gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo sapiens] Length = 514 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W ++++ + S V H + Sbjct: 167 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLSENSTSGSTQL-------VLRHCIREG 218 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 +D+P N V +L +N++ L S DG+ +W + L+ L Sbjct: 219 GQDVPS------NKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTL 262 Score = 31.6 bits (70), Expect = 1.5 Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 41/151 (27%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +P+ LLA+ D+ +L I+ + + CV D H I++I W Sbjct: 352 VNAIKWDPTGNLLASCSDDM-TLKIWSMKQDN--CVHDLQAHNKEIYTIKWSPTGPGTNN 408 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 ++ M S S D ++ LW+V + + +H + PVY+ Sbjct: 409 PNANLMLASASFDSTVRLWDVDRGICIHTLTKH---QEPVYS------------------ 447 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAE 282 +AF+ + L + S D H+W + Sbjct: 448 ------VAFSPDGRYLASGSFDKCVHIWNTQ 472 >gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] Length = 526 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 41/152 (26%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +PS LLA+ D+ +L I+ + VC+ D H I++I W Sbjct: 364 VNAIKWDPSGMLLASCSDDM-TLKIWSMK--QEVCIHDLQAHNKEIYTIKWSPTGPATSN 420 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 S+ M S S D ++ LW++ V T + +H + PVY+ Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKH---QEPVYS------------------ 459 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAEN 283 +AF+ K L + S D H+W ++ Sbjct: 460 ------VAFSPDGKYLASGSFDKCVHIWNTQS 485 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W + ++ + S V H + Sbjct: 179 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLNEN-------SNGGSTQLVLRHCIREG 230 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 D+P N V +L +N L S DG+ +W + L+ L Sbjct: 231 GHDVPS------NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 274 >gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] Length = 526 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 41/152 (26%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +PS LLA+ D+ +L I+ + VC+ D H I++I W Sbjct: 364 VNAIKWDPSGMLLASCSDDM-TLKIWSMK--QEVCIHDLQAHNKEIYTIKWSPTGPATSN 420 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 S+ M S S D ++ LW++ V T + +H + PVY+ Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKH---QEPVYS------------------ 459 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAEN 283 +AF+ K L + S D H+W ++ Sbjct: 460 ------VAFSPDGKYLASGSFDKCVHIWNTQS 485 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W + ++ + S V H + Sbjct: 179 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLNEN-------SNGGSTQLVLRHCIREG 230 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 D+P N V +L +N L S DG+ +W + L+ L Sbjct: 231 GHDVPS------NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 274 >gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] Length = 577 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 41/152 (26%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +PS LLA+ D+ +L I+ + VC+ D H I++I W Sbjct: 415 VNAIKWDPSGMLLASCSDDM-TLKIWSMK--QEVCIHDLQAHNKEIYTIKWSPTGPATSN 471 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 S+ M S S D ++ LW++ V T + +H + PVY+ Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKH---QEPVYS------------------ 510 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAEN 283 +AF+ K L + S D H+W ++ Sbjct: 511 ------VAFSPDGKYLASGSFDKCVHIWNTQS 536 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W + ++ + S V H + Sbjct: 230 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLNEN-------SNGGSTQLVLRHCIREG 281 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 D+P N V +L +N L S DG+ +W + L+ L Sbjct: 282 GHDVPS------NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 325 >gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] Length = 577 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 41/152 (26%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWI-------- 193 ++AI+ +PS LLA+ D+ +L I+ + VC+ D H I++I W Sbjct: 415 VNAIKWDPSGMLLASCSDDM-TLKIWSMK--QEVCIHDLQAHNKEIYTIKWSPTGPATSN 471 Query: 194 --SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKALKDIPKEDTNPD 251 S+ M S S D ++ LW++ V T + +H + PVY+ Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKH---QEPVYS------------------ 510 Query: 252 NCKVRALAFNNKNKELGAVSLDGYFHLWKAEN 283 +AF+ K L + S D H+W ++ Sbjct: 511 ------VAFSPDGKYLASGSFDKCVHIWNTQS 536 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 182 GHKDWIFSIAW--ISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKA 239 GH+ +F AW +SD +A SGS D + +W + ++ + S V H + Sbjct: 230 GHESEVFICAWNPVSDLLA-SGSGDSTARIWNLNEN-------SNGGSTQLVLRHCIREG 281 Query: 240 LKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLL 289 D+P N V +L +N L S DG+ +W + L+ L Sbjct: 282 GHDVPS------NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTL 325 >gi|75709220 cleavage stimulation factor subunit 1 [Homo sapiens] Length = 431 Score = 37.4 bits (85), Expect = 0.028 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 5/91 (5%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPV--CVGDDGHKDWIFSIAWISDT-MAV 199 + +I +PS + G +P +L +Y + T C D H D I S+ + S M V Sbjct: 220 LRSISFHPSGDFILVGTQHP-TLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278 Query: 200 SGSRDGSMGLWE-VTDDVLTKSDARHNVSRV 229 +GS+DG + LW+ V++ +T + H+ + V Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEV 309 >gi|4557491 cleavage stimulation factor subunit 1 [Homo sapiens] Length = 431 Score = 37.4 bits (85), Expect = 0.028 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 5/91 (5%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPV--CVGDDGHKDWIFSIAWISDT-MAV 199 + +I +PS + G +P +L +Y + T C D H D I S+ + S M V Sbjct: 220 LRSISFHPSGDFILVGTQHP-TLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278 Query: 200 SGSRDGSMGLWE-VTDDVLTKSDARHNVSRV 229 +GS+DG + LW+ V++ +T + H+ + V Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEV 309 >gi|75709217 cleavage stimulation factor subunit 1 [Homo sapiens] Length = 431 Score = 37.4 bits (85), Expect = 0.028 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 5/91 (5%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPV--CVGDDGHKDWIFSIAWISDT-MAV 199 + +I +PS + G +P +L +Y + T C D H D I S+ + S M V Sbjct: 220 LRSISFHPSGDFILVGTQHP-TLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278 Query: 200 SGSRDGSMGLWE-VTDDVLTKSDARHNVSRV 229 +GS+DG + LW+ V++ +T + H+ + V Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEV 309 >gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] Length = 1298 Score = 35.8 bits (81), Expect = 0.082 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 151 SRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAW--ISDTMAVSGSRDGSMG 208 ++ ++ATG ++ N Y + D GH +F + W + + + SGS DG++ Sbjct: 509 NKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVR 568 Query: 209 LWEVTDD 215 +W+ T D Sbjct: 569 IWDYTQD 575 >gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] Length = 1322 Score = 35.8 bits (81), Expect = 0.082 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 151 SRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAW--ISDTMAVSGSRDGSMG 208 ++ ++ATG ++ N Y + D GH +F + W + + + SGS DG++ Sbjct: 533 NKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVR 592 Query: 209 LWEVTDD 215 +W+ T D Sbjct: 593 IWDYTQD 599 >gi|17402902 guanine nucleotide binding protein beta-subunit-like polypeptide [Homo sapiens] Length = 327 Score = 34.3 bits (77), Expect = 0.24 Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 2/71 (2%) Query: 142 GIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAWISDTMAVSG 201 GI + + P R +LAT G + + + ++ T+ P+ V H + +A+ +D + +G Sbjct: 255 GIAEVTIRPDRKILATAGWD-HRIRVFHWRTMQPLAVLAF-HSAAVQCVAFTADGLLAAG 312 Query: 202 SRDGSMGLWEV 212 S+D + LW + Sbjct: 313 SKDQRISLWSL 323 >gi|41281564 WD repeat domain 37 [Homo sapiens] Length = 494 Score = 34.3 bits (77), Expect = 0.24 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 11/122 (9%) Query: 92 VFASQWL-NHRQVVCGTKCNTLFVVDVQTSQITKIPILKDREPGGVTQQGCGIHAIELNP 150 V AS WL +Q V + T + DV+TS++ D+E C H + Sbjct: 284 VIASDWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQE-----LTHCCTHPTQ--- 335 Query: 151 SRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAWISDTMAVSGSRDGSMGLW 210 R ++ + D L +R P++ V V GH D + S + VSGS D ++ +W Sbjct: 336 -RLVVTSSRDTTFRLWDFRDPSIHSVNVFQ-GHTDTVTSAVFTVGDNVVSGSDDRTVKVW 393 Query: 211 EV 212 ++ Sbjct: 394 DL 395 >gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sapiens] Length = 390 Score = 33.9 bits (76), Expect = 0.31 Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAWI--SDTMAVS 200 ++ + NP + G ++A++ L L + HKD IF + W ++T+ S Sbjct: 241 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILAS 300 Query: 201 GSRDGSMGLWEVT 213 D + +W+++ Sbjct: 301 SGTDRRLNVWDLS 313 >gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sapiens] Length = 424 Score = 33.9 bits (76), Expect = 0.31 Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAWI--SDTMAVS 200 ++ + NP + G ++A++ L L + HKD IF + W ++T+ S Sbjct: 275 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILAS 334 Query: 201 GSRDGSMGLWEVT 213 D + +W+++ Sbjct: 335 SGTDRRLNVWDLS 347 >gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapiens] Length = 425 Score = 33.9 bits (76), Expect = 0.31 Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAWI--SDTMAVS 200 ++ + NP + G ++A++ L L + HKD IF + W ++T+ S Sbjct: 276 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILAS 335 Query: 201 GSRDGSMGLWEVT 213 D + +W+++ Sbjct: 336 SGTDRRLNVWDLS 348 >gi|16554629 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 33.9 bits (76), Expect = 0.31 Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 26/119 (21%) Query: 182 GHKDWIFSIAWISDT-MAVSGSRDGSMGLWEVTDDVLTKSDARHN--------------- 225 GHK I +AW SD+ + VS S D ++ +W+V+ K+ H+ Sbjct: 85 GHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLI 144 Query: 226 -----VSRVPVYAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLW 279 V ++ T K LK +P V A+ FN + + S DG +W Sbjct: 145 VSGSFDESVRIWDVKTGKCLKTLPAHSD-----PVSAVHFNRDGSLIVSSSYDGLCRIW 198 Score = 30.8 bits (68), Expect = 2.6 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 24/151 (15%) Query: 182 GHKDWIFSIAWISDT-MAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVY-------- 232 GH +++F + + + VSGS D S+ +W+V K+ H+ V+ Sbjct: 127 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI 186 Query: 233 --------AHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENT 284 I A K + DN V + F+ K + A +LD LW + + Sbjct: 187 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW--DYS 244 Query: 285 LSKLLSTKLPYCRENVCL-----AYGSEWSV 310 K L T + E C+ G +W V Sbjct: 245 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275 >gi|16554627 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 33.9 bits (76), Expect = 0.31 Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 26/119 (21%) Query: 182 GHKDWIFSIAWISDT-MAVSGSRDGSMGLWEVTDDVLTKSDARHN--------------- 225 GHK I +AW SD+ + VS S D ++ +W+V+ K+ H+ Sbjct: 85 GHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLI 144 Query: 226 -----VSRVPVYAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLW 279 V ++ T K LK +P V A+ FN + + S DG +W Sbjct: 145 VSGSFDESVRIWDVKTGKCLKTLPAHSD-----PVSAVHFNRDGSLIVSSSYDGLCRIW 198 Score = 30.8 bits (68), Expect = 2.6 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 24/151 (15%) Query: 182 GHKDWIFSIAWISDT-MAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVY-------- 232 GH +++F + + + VSGS D S+ +W+V K+ H+ V+ Sbjct: 127 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI 186 Query: 233 --------AHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENT 284 I A K + DN V + F+ K + A +LD LW + + Sbjct: 187 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW--DYS 244 Query: 285 LSKLLSTKLPYCRENVCL-----AYGSEWSV 310 K L T + E C+ G +W V Sbjct: 245 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275 >gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [Homo sapiens] Length = 340 Score = 33.5 bits (75), Expect = 0.41 Identities = 35/152 (23%), Positives = 65/152 (42%), Gaps = 17/152 (11%) Query: 79 LKEREFHLGTLNKVFASQW-LNHRQVVCGTKCNTLFVVD-VQTSQITKIPILKDREPGGV 136 ++ R G L K++A W + R +V ++ L + D T+++ IP+ Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPL--------- 95 Query: 137 TQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDP-VCVGDD--GHKDWIFSIAWI 193 + + PS +A GG + N +IY L T + V V + GH ++ ++ Sbjct: 96 --RSSWVMTCAYAPSGNFVACGGLD-NICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL 152 Query: 194 SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHN 225 D ++ S D + LW++ T A H+ Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184 Score = 30.4 bits (67), Expect = 3.4 Identities = 38/143 (26%), Positives = 58/143 (40%), Gaps = 9/143 (6%) Query: 88 TLNKVFASQWLNHRQVVCGTKCNTLFVVDVQTSQITKIPILKDREPGGVTQQGCGIHAIE 147 T NKV A + + C + FV I I LK RE + H Sbjct: 86 TTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGY 145 Query: 148 LNPSRTL-----LATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAWISDTMA-VSG 201 L+ R L + + GD + A++ + T VG GH + S++ D VSG Sbjct: 146 LSCCRFLDDNQIITSSGDT--TCALWDIETGQQT-VGFAGHSGDVMSLSLAPDGRTFVSG 202 Query: 202 SRDGSMGLWEVTDDVLTKSDARH 224 + D S+ LW+V D + ++ H Sbjct: 203 ACDASIKLWDVRDSMCRQTFIGH 225 >gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [Homo sapiens] Length = 340 Score = 32.7 bits (73), Expect = 0.69 Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 17/151 (11%) Query: 79 LKEREFHLGTLNKVFASQW-LNHRQVVCGTKCNTLFVVD-VQTSQITKIPILKDREPGGV 136 ++ R G L K++A W + R +V ++ L + D T+++ IP+ Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPL--------- 95 Query: 137 TQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDP-VCVGDD--GHKDWIFSIAWI 193 + + PS +A GG + N +IY L T + V V + GH ++ ++ Sbjct: 96 --RSSWVMTCAYAPSGNYVACGGLD-NICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL 152 Query: 194 SDTMAVSGSRDGSMGLWEVTDDVLTKSDARH 224 D V+ S D + LW++ T + H Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGH 183 >gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] Length = 425 Score = 32.7 bits (73), Expect = 0.69 Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 143 IHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGDDGHKDWIFSIAWI--SDTMAVS 200 ++ + NP + G ++A++ L L + HKD IF + W ++T+ S Sbjct: 275 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILAS 334 Query: 201 GSRDGSMGLWEVT 213 D + +W+++ Sbjct: 335 SGTDRRLNVWDLS 347 >gi|62234461 Notchless gene homolog isoform a [Homo sapiens] Length = 485 Score = 32.7 bits (73), Expect = 0.69 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 7/70 (10%) Query: 145 AIELNPSRTLLATGGDNPNSLAIYRLPTLDP--VCVGDDGHKDWIFSIAWISD-TMAVSG 201 ++ +P+ LA+G + ++ + L T P C GH+ W+ SI+W D SG Sbjct: 119 SVAFSPTGKYLASGSGD-TTVRFWDLSTETPHFTC---KGHRHWVLSISWSPDGRKLASG 174 Query: 202 SRDGSMGLWE 211 ++G + LW+ Sbjct: 175 CKNGQILLWD 184 Score = 31.2 bits (69), Expect = 2.0 Identities = 13/32 (40%), Positives = 22/32 (68%), Gaps = 1/32 (3%) Query: 182 GHKDWIFSIAWISDT-MAVSGSRDGSMGLWEV 212 GH ++ IAW +D+ + VSGS D ++ +W+V Sbjct: 412 GHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 443 >gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [Homo sapiens] Length = 340 Score = 32.3 bits (72), Expect = 0.91 Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 17/152 (11%) Query: 79 LKEREFHLGTLNKVFASQW-LNHRQVVCGTKCNTLFVVD-VQTSQITKIPILKDREPGGV 136 ++ R G L K++A W + R +V ++ L + D T+++ IP+ Sbjct: 45 MRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPL--------- 95 Query: 137 TQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDP-VCVGDD--GHKDWIFSIAWI 193 + + PS +A GG + N +IY L T + V V + GH ++ ++ Sbjct: 96 --RSSWVMTCAYAPSGNYVACGGLD-NICSIYNLKTREGNVRVSRELPGHTGYLSCCRFL 152 Query: 194 SDTMAVSGSRDGSMGLWEVTDDVLTKSDARHN 225 D+ V+ S D + LW++ T + H+ Sbjct: 153 DDSQIVTSSGDTTCALWDIETAQQTTTFTGHS 184 >gi|5174447 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [Homo sapiens] Length = 317 Score = 32.3 bits (72), Expect = 0.91 Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 39/128 (30%) Query: 182 GHKDWIFSIAWISD-TMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKAL 240 GH ++ + SD A+SGS DG++ LW++T T+ H Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHT--------------- 105 Query: 241 KDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLSTKLPYCRENV 300 KD V ++AF++ N+++ + S D LW NTL C+ V Sbjct: 106 KD------------VLSVAFSSDNRQIVSGSRDKTIKLW---NTLG--------VCKYTV 142 Query: 301 CLAYGSEW 308 SEW Sbjct: 143 QDESHSEW 150 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,962,664 Number of Sequences: 37866 Number of extensions: 858183 Number of successful extensions: 2109 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 5 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 2055 Number of HSP's gapped (non-prelim): 88 length of query: 453 length of database: 18,247,518 effective HSP length: 106 effective length of query: 347 effective length of database: 14,233,722 effective search space: 4939101534 effective search space used: 4939101534 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.