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Search of human proteins with 22218349
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b
[Homo sapiens]
(382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 768 0.0
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 750 0.0
gi|4557489 cone-rod homeobox protein [Homo sapiens] 103 3e-22
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 102 6e-22
gi|24497589 aristaless related homeobox [Homo sapiens] 100 3e-21
gi|7706659 paired related homeobox 2 [Homo sapiens] 99 6e-21
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 99 8e-21
gi|46249382 paired-like homeobox 2a [Homo sapiens] 99 8e-21
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 98 1e-20
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 96 4e-20
gi|12707580 paired-like homeobox 2b [Homo sapiens] 96 7e-20
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 95 1e-19
gi|122937321 UNC homeobox [Homo sapiens] 94 2e-19
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 93 5e-19
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 93 5e-19
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 93 5e-19
gi|34365783 visual system homeobox 2 [Homo sapiens] 92 6e-19
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 92 6e-19
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 92 6e-19
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 92 6e-19
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 92 8e-19
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 92 1e-18
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 92 1e-18
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 92 1e-18
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 92 1e-18
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 91 2e-18
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 91 2e-18
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 91 2e-18
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 91 2e-18
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 91 2e-18
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 768 bits (1983), Expect = 0.0
Identities = 382/382 (100%), Positives = 382/382 (100%)
Query: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIIL 60
MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIIL
Sbjct: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIIL 60
Query: 61 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 120
EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK
Sbjct: 61 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 120
Query: 121 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 180
NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH
Sbjct: 121 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 180
Query: 181 LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI 240
LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI
Sbjct: 181 LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI 240
Query: 241 TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA 300
TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA
Sbjct: 241 TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA 300
Query: 301 AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS 360
AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS
Sbjct: 301 AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS 360
Query: 361 IENLRLRAKQHAASLGLDTLPN 382
IENLRLRAKQHAASLGLDTLPN
Sbjct: 361 IENLRLRAKQHAASLGLDTLPN 382
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 750 bits (1936), Expect = 0.0
Identities = 377/382 (98%), Positives = 377/382 (98%), Gaps = 5/382 (1%)
Query: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIIL 60
MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLA DIIL
Sbjct: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLA-----DIIL 55
Query: 61 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 120
EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK
Sbjct: 56 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 115
Query: 121 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 180
NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH
Sbjct: 116 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 175
Query: 181 LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI 240
LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI
Sbjct: 176 LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI 235
Query: 241 TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA 300
TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA
Sbjct: 236 TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA 295
Query: 301 AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS 360
AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS
Sbjct: 296 AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS 355
Query: 361 IENLRLRAKQHAASLGLDTLPN 382
IENLRLRAKQHAASLGLDTLPN
Sbjct: 356 IENLRLRAKQHAASLGLDTLPN 377
>gi|4557489 cone-rod homeobox protein [Homo sapiens]
Length = 299
Score = 103 bits (257), Expect = 3e-22
Identities = 87/252 (34%), Positives = 118/252 (46%), Gaps = 32/252 (12%)
Query: 39 PSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDV 98
P H A L+G + + Y S RKQRR RT FT QLE LE F KT YPDV
Sbjct: 7 PGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDV 66
Query: 99 VMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKA-EAPT 157
RE +A+ NLPE+RVQVWFKNRRAK R++++ +++Q +A+ + KA +P
Sbjct: 67 YAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPR 126
Query: 158 PDTQL--------DTEQPPRLP---GSDPPAELHLSLSEQSASESAPEDQ--------PD 198
P T + D+ PP LP GS A +S+ ++ PE Q P
Sbjct: 127 PSTDVCPDPLGISDSYSPP-LPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPS 185
Query: 199 REEDP--------RAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLL 250
P A P A SP + GL SP G ++P++ G +
Sbjct: 186 LTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD-PYLSPMVPQLGGPALSPLS--GPSV 242
Query: 251 GPSHSYSSSPLS 262
GPS + S + LS
Sbjct: 243 GPSLAQSPTSLS 254
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 102 bits (254), Expect = 6e-22
Identities = 97/313 (30%), Positives = 127/313 (40%), Gaps = 71/313 (22%)
Query: 50 LAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTN 109
LAG + Y + RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ N
Sbjct: 17 LAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKIN 76
Query: 110 LPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPR 169
LPE+RVQVWFKNRRAK R++Q+S G G T+ P
Sbjct: 77 LPESRVQVWFKNRRAKCRQQQQS----------------GSG------------TKSRPA 108
Query: 170 LPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGS 229
S P + E S SES +G P A S + S +
Sbjct: 109 KKKSSP-------VRESSGSES-------------SGQFTPPAVSSSASSSSSASSSSAN 148
Query: 230 PKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSL----FRLQEQFRQHMAATNNLVHYSS 285
P A + L PVA L P+ S SP S+ + +AA +N +S
Sbjct: 149 PAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSN----TS 204
Query: 286 FEVGGPAPAAAAAAAAVP------------YLGVNMAPLGSLHCQSYYQSLSAAAAAHQG 333
A AA AAA+ P Y + + G + C SY + + HQ
Sbjct: 205 CMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ- 263
Query: 334 VWGSPLLPAPPAG 346
SP+ P+ AG
Sbjct: 264 --LSPMAPSSMAG 274
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 100 bits (248), Expect = 3e-21
Identities = 112/361 (31%), Positives = 141/361 (39%), Gaps = 92/361 (25%)
Query: 27 AAQQAQHAPDYRPSVHALTLAERLAGCTFQDIIL-----EARYGSQHRKQRRSRTAFTAQ 81
AA A + P L E G +D + ++ G RKQRR RT FT+
Sbjct: 279 AAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSY 338
Query: 82 QLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQ 141
QLE LE+ FQKTHYPDV RE LAM +L EARVQVWF+NRRAK+RK++
Sbjct: 339 QLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKRE----------- 387
Query: 142 KEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREE 201
KA A T PP LP P + H LS + P P +
Sbjct: 388 ----------KAGAQT--------HPPGLPFPGPLSATH-PLSPYLDASPFPPHHPALDS 428
Query: 202 DPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPL 261
A A A + + P PG L P S +PL
Sbjct: 429 AWTAAA------------------------AAAAAAFPSLPPPPGSASLPP----SGAPL 460
Query: 262 SLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYY 321
L S+F A + A L MAPL S
Sbjct: 461 GL--------------------STFLGAAVFRHPAFISPAFGRLFSTMAPLTS------- 493
Query: 322 QSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASL-GLDTL 380
+ +AAA Q A A PA+A + + +SI LRL+AK+HAA L L+ L
Sbjct: 494 -ASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNIL 552
Query: 381 P 381
P
Sbjct: 553 P 553
Score = 30.8 bits (68), Expect = 2.1
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 13/58 (22%)
Query: 289 GGPAPAAAAAAAAVPYLGVNMAPLGSL-HCQSYYQSLSAAAAAHQGVWGSPLLPAPPA 345
G A AAAAAAAA L ++ AP S+ +SY ++ G+P +P PPA
Sbjct: 143 GAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYREN------------GAPFVPPPPA 188
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 99.0 bits (245), Expect = 6e-21
Identities = 58/133 (43%), Positives = 78/133 (58%), Gaps = 12/133 (9%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
+KQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 102 KKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRR 161
Query: 129 KQRSL---QKEQLQKQKEAEGSHGEGKAEAPT---PDTQLDTEQ------PPRLPGSDPP 176
+R++ + L K E + + A PT PD T PP PGS P
Sbjct: 162 NERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGP 221
Query: 177 AELHLSLSEQSAS 189
A ++++ AS
Sbjct: 222 ATPGVNMANSIAS 234
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 98.6 bits (244), Expect = 8e-21
Identities = 48/74 (64%), Positives = 60/74 (81%)
Query: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
S K+RR+RT FT+ QLE LEK FQKTHYPDV RE+LAM T+L EARVQVWF+NRRAK
Sbjct: 209 SNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAK 268
Query: 126 FRKKQRSLQKEQLQ 139
+RK++R Q +Q++
Sbjct: 269 WRKRERFGQMQQVR 282
Score = 33.9 bits (76), Expect = 0.25
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 13/87 (14%)
Query: 293 PAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASA 352
P + A++ +L V+ A GS Q++ SL AA+ G+ G L P
Sbjct: 338 PPGSGASSVTDFLSVSGA--GSHVGQTHMGSLFGAASLSPGLNGYELNGEP--------- 386
Query: 353 TLNSKTTSIENLRLRAKQHAASLGLDT 379
+ KT+SI LR++AK+H+A++ T
Sbjct: 387 --DRKTSSIAALRMKAKEHSAAISWAT 411
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 98.6 bits (244), Expect = 8e-21
Identities = 65/182 (35%), Positives = 84/182 (46%), Gaps = 26/182 (14%)
Query: 67 QHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKF 126
+ RKQRR RT FT+ QL+ LE+ F +THYPD+ RE LA+ +L EARVQVWF+NRRAKF
Sbjct: 86 EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145
Query: 127 RKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQ 186
RK++R+ K A G+ G K EA D S++
Sbjct: 146 RKQERA------ASAKGAAGAAGAKKGEARCSSEDDD--------------------SKE 179
Query: 187 SASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPG 246
S P+ P G P+ SP + G G G G+L G
Sbjct: 180 STCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGG 239
Query: 247 GG 248
GG
Sbjct: 240 GG 241
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 97.8 bits (242), Expect = 1e-20
Identities = 84/246 (34%), Positives = 115/246 (46%), Gaps = 27/246 (10%)
Query: 65 GSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRA 124
GS +KQRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRA
Sbjct: 56 GSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 115
Query: 125 KFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLS 184
K+RK++RS Q E + A E P P L + P A +
Sbjct: 116 KWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL--APPLAAKTFPFA 173
Query: 185 EQSASESAPEDQP-DREEDPRAGAEDPKAEKSPG-----ADSKGLGCKRGSPKADSPGSL 238
S + QP A + P A +PG +GLG G P +P ++
Sbjct: 174 FNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLG---GGPPGLAPAAV 230
Query: 239 TITPVA-PGGGLLGPSHSYSSSPL--------SLFRLQEQFRQHMAATNNLVHYSSFEVG 289
+ V+ P + + +SSP SL L+ + +QH + + VH
Sbjct: 231 SSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVH------- 283
Query: 290 GPAPAA 295
GP PAA
Sbjct: 284 GPPPAA 289
Score = 32.7 bits (73), Expect = 0.56
Identities = 40/124 (32%), Positives = 52/124 (41%), Gaps = 33/124 (26%)
Query: 283 YSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSL------SAAAA------- 329
Y ++ AP AA + VN+ PL S S S+ SAAAA
Sbjct: 153 YGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGP 212
Query: 330 -AHQGVWGSP--LLPA---------PPAGLAPASATLNSK--------TTSIENLRLRAK 369
A QG+ G P L PA P A A A+A S +S+ +LRL+AK
Sbjct: 213 GALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAK 272
Query: 370 QHAA 373
QHA+
Sbjct: 273 QHAS 276
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 96.3 bits (238), Expect = 4e-20
Identities = 54/104 (51%), Positives = 61/104 (58%), Gaps = 8/104 (7%)
Query: 65 GSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRA 124
G RKQRR+RT FT QQLEALE F +THYPDV RE LAM NL EARVQVWF+NRRA
Sbjct: 32 GFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRA 91
Query: 125 KFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPP 168
K+RK +R + E E AE P + PP
Sbjct: 92 KWRKTERG--------ASDQEPGAKEPMAEVTPPPVRNINSPPP 127
Score = 32.0 bits (71), Expect = 0.95
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 13/99 (13%)
Query: 289 GGPAPAAAAAAAAVPYLGVNMAPLGS----------LHCQSYYQSLSAAAAAHQGVWGSP 338
G A + A A LG + P G L+ +Y Q+LS A+ G S
Sbjct: 128 GDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSC 187
Query: 339 LLPAPPAGLA--PASATLNSKTTSIENLRLRAKQHAASL 375
+P P GL+ P +++T S+ LR++A++H+ ++
Sbjct: 188 CVP-DPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAV 225
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 95.5 bits (236), Expect = 7e-20
Identities = 67/198 (33%), Positives = 96/198 (48%), Gaps = 17/198 (8%)
Query: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
++ RKQRR RT FT+ QL+ LE+ F +THYPD+ RE LA+ +L EARVQVWF+NRRAK
Sbjct: 93 NEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAK 152
Query: 126 FRKKQRSLQKEQLQKQ-----KEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 180
FRK++R+ + K+++ S + EA + D T P P P +
Sbjct: 153 FRKQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPD-STGGPGPNPNPTPSCGAN 211
Query: 181 --------LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPK- 231
+ + +A P +P + A A A + A + G G P
Sbjct: 212 GGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQ 271
Query: 232 --ADSPGSLTITPVAPGG 247
A PG +T P + GG
Sbjct: 272 GWAPGPGPITSIPDSLGG 289
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 94.7 bits (234), Expect = 1e-19
Identities = 46/68 (67%), Positives = 56/68 (82%)
Query: 70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 129
K+RR RT FT+ QLE LEK FQKTHYPDV +RE+LA+ T L EARVQVWF+NRRAK+RK+
Sbjct: 131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKR 190
Query: 130 QRSLQKEQ 137
+R Q +Q
Sbjct: 191 ERYGQIQQ 198
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 94.4 bits (233), Expect = 2e-19
Identities = 78/264 (29%), Positives = 110/264 (41%), Gaps = 26/264 (9%)
Query: 70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 129
K+RR+RT FT QLE LEK F ++HYPDV MRE LA+ +L E+RVQVWF+NRRAK+RKK
Sbjct: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
Query: 130 QRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAE--------LHL 181
+ + + + A SH + P ++ ++ ++ E HL
Sbjct: 164 ENT----KKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHL 219
Query: 182 SLSEQSASESAPEDQPDREE---DPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSL 238
+ SAP D P P A K PGA + G +P + P
Sbjct: 220 HSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPG 279
Query: 239 TITPV-----------APGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFE 287
T P P G + S P + E+ + + S
Sbjct: 280 TCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLS 339
Query: 288 VGGPAPAAAAAAAAVPYLGVNMAP 311
P AA+ AAA G++ AP
Sbjct: 340 DSPPRRKAASNAAAAAAAGLDFAP 363
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 92.8 bits (229), Expect = 5e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 87 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 146
Query: 126 FRKKQRSLQKE 136
+RK++R+ Q E
Sbjct: 147 WRKRERNQQAE 157
Score = 32.0 bits (71), Expect = 0.95
Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 166 QPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEK 214
QP L S E+H ++S+ S+ E+A +D+ + ++ GAEDP +K
Sbjct: 43 QPRSLDSSKHRLEVH-TISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKK 90
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 92.8 bits (229), Expect = 5e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 34 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 93
Query: 126 FRKKQRSLQKE 136
+RK++R+ Q E
Sbjct: 94 WRKRERNQQAE 104
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 92.8 bits (229), Expect = 5e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 80 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 139
Query: 126 FRKKQRSLQKE 136
+RK++R+ Q E
Sbjct: 140 WRKRERNQQAE 150
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 92.4 bits (228), Expect = 6e-19
Identities = 55/155 (35%), Positives = 88/155 (56%), Gaps = 3/155 (1%)
Query: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
++ RK+RR RT FT+ QLE LEK F + HYPDV RE LAM T LPE R+QVWF+NRRAK
Sbjct: 143 TKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAK 202
Query: 126 FRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSE 185
+RK+++ + + + G+ + P P++ L + + + P S
Sbjct: 203 WRKREKCWGRSSVMAEYGLYGA--MVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSL 260
Query: 186 QSASESAPEDQPDREEDPRAGAEDPKAEKSPGADS 220
++A+ES + + +R+ P+ + + E+ P A +
Sbjct: 261 EAAAESGRKPEGERQALPKLDKME-QDERGPDAQA 294
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 92.4 bits (228), Expect = 6e-19
Identities = 43/61 (70%), Positives = 50/61 (81%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LEK F++THYPD+ RE LA T L EARVQVWF NRRA++RK
Sbjct: 215 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 274
Query: 129 K 129
+
Sbjct: 275 Q 275
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 92.4 bits (228), Expect = 6e-19
Identities = 43/61 (70%), Positives = 50/61 (81%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LEK F++THYPD+ RE LA T L EARVQVWF NRRA++RK
Sbjct: 213 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 272
Query: 129 K 129
+
Sbjct: 273 Q 273
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 92.4 bits (228), Expect = 6e-19
Identities = 43/61 (70%), Positives = 50/61 (81%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LEK F++THYPD+ RE LA T L EARVQVWF NRRA++RK
Sbjct: 215 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 274
Query: 129 K 129
+
Sbjct: 275 Q 275
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 92.0 bits (227), Expect = 8e-19
Identities = 58/146 (39%), Positives = 72/146 (49%), Gaps = 16/146 (10%)
Query: 64 YGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRR 123
Y + RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRR
Sbjct: 31 YPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRR 90
Query: 124 AKFRKKQRSLQ----------KEQLQKQKEAEGSHGEGKAEAPTPDTQLDT----EQPPR 169
AK R++Q+ Q K++ +E G P T + T P
Sbjct: 91 AKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVS 150
Query: 170 L--PGSDPPAELHLSLSEQSASESAP 193
+ P S P LS S S P
Sbjct: 151 IWSPASISPLSDPLSTSSSCMQRSYP 176
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 91.7 bits (226), Expect = 1e-18
Identities = 42/69 (60%), Positives = 56/69 (81%)
Query: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
++ +KQRR RT FT+QQL+ LE TFQ+ YPD+ MRE +A+ TNL E RV+VWFKNRRAK
Sbjct: 84 AKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAK 143
Query: 126 FRKKQRSLQ 134
+RK++R+ Q
Sbjct: 144 WRKRERNQQ 152
Score = 28.9 bits (63), Expect = 8.1
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 12/66 (18%)
Query: 166 QPPRLPGSDPPAELHLSLS-------EQSASESAPEDQPDREEDPRAGAEDPKAEKSPGA 218
+PP P D HL+ E SASES+ + P++E R G +PK + GA
Sbjct: 18 RPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKE---RGG--EPKGPEDSGA 72
Query: 219 DSKGLG 224
G G
Sbjct: 73 GGTGCG 78
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 91.7 bits (226), Expect = 1e-18
Identities = 43/62 (69%), Positives = 53/62 (85%)
Query: 70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 129
K+RR+RT F+ QLE LEK FQKTHYPDV RE+LA+ T+L EARVQVWF+NRRAK+RK+
Sbjct: 152 KKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKR 211
Query: 130 QR 131
+R
Sbjct: 212 ER 213
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 91.7 bits (226), Expect = 1e-18
Identities = 41/65 (63%), Positives = 53/65 (81%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 129 KQRSL 133
+R++
Sbjct: 152 NERAM 156
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 91.7 bits (226), Expect = 1e-18
Identities = 41/65 (63%), Positives = 53/65 (81%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 129 KQRSL 133
+R++
Sbjct: 152 NERAM 156
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 216 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 274
Query: 129 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 184
KQ + G PT + QP +P SDP + +H L
Sbjct: 275 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 334
Query: 185 EQSASESAPEDQPD 198
+ +S PD
Sbjct: 335 PSTVHQSTIPSNPD 348
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 129 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 184
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 185 EQSASESAPEDQPD 198
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 129 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 184
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 185 EQSASESAPEDQPD 198
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 129 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 184
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 185 EQSASESAPEDQPD 198
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 129 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 184
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 185 EQSASESAPEDQPD 198
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,887,649
Number of Sequences: 37866
Number of extensions: 914897
Number of successful extensions: 7029
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 341
Number of HSP's successfully gapped in prelim test: 485
Number of HSP's that attempted gapping in prelim test: 5813
Number of HSP's gapped (non-prelim): 1678
length of query: 382
length of database: 18,247,518
effective HSP length: 104
effective length of query: 278
effective length of database: 14,309,454
effective search space: 3978028212
effective search space used: 3978028212
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.