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Search of human proteins with 222136605
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222136605 tetratricopeptide repeat domain 26 isoform 2 [Homo
sapiens]
(487 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136605 tetratricopeptide repeat domain 26 isoform 2 [Homo ... 984 0.0
gi|222136634 tetratricopeptide repeat domain 26 isoform 1 [Homo ... 954 0.0
gi|222136607 tetratricopeptide repeat domain 26 isoform 3 [Homo ... 870 0.0
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 42 0.002
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 34 0.26
gi|70980549 programmed cell death 11 [Homo sapiens] 34 0.34
gi|31317299 inhibitor of DNA binding 1 isoform a [Homo sapiens] 33 0.58
gi|31317297 inhibitor of DNA binding 1 isoform b [Homo sapiens] 33 0.58
gi|225545550 TEL2, telomere maintenance 2, homolog [Homo sapiens] 32 1.00
gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens] 32 1.00
gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens] 32 1.7
gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo sa... 32 1.7
gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo sa... 32 1.7
gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo sa... 32 1.7
gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens] 32 1.7
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 31 2.2
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 30 3.8
gi|169161714 PREDICTED: tetratricopeptide repeat domain 34 [Homo... 30 3.8
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 30 3.8
gi|169162130 PREDICTED: tetratricopeptide repeat domain 34 [Homo... 30 3.8
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 30 3.8
gi|27262638 sperm associated antigen 1 [Homo sapiens] 30 3.8
gi|27262636 sperm associated antigen 1 [Homo sapiens] 30 3.8
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 30 4.9
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 30 4.9
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 30 4.9
gi|166235180 tetratricopeptide repeat domain 22 isoform 1 [Homo ... 30 4.9
gi|153792103 tetratricopeptide repeat domain 22 isoform 2 [Homo ... 30 4.9
gi|22749211 transmembrane and tetratricopeptide repeat containin... 30 6.5
gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ... 29 8.4
>gi|222136605 tetratricopeptide repeat domain 26 isoform 2 [Homo
sapiens]
Length = 487
Score = 984 bits (2543), Expect = 0.0
Identities = 487/487 (100%), Positives = 487/487 (100%)
Query: 1 MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTN 60
MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTN
Sbjct: 1 MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTN 60
Query: 61 LWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS 120
LWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS
Sbjct: 61 LWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS 120
Query: 121 RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD 180
RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD
Sbjct: 121 RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD 180
Query: 181 NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA 240
NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA
Sbjct: 181 NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA 240
Query: 241 ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD 300
ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD
Sbjct: 241 ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD 300
Query: 301 VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP 360
VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP
Sbjct: 301 VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP 360
Query: 361 GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ 420
GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ
Sbjct: 361 GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ 420
Query: 421 SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKRDPSRSA 480
SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKRDPSRSA
Sbjct: 421 SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKRDPSRSA 480
Query: 481 PFTEKHR 487
PFTEKHR
Sbjct: 481 PFTEKHR 487
>gi|222136634 tetratricopeptide repeat domain 26 isoform 1 [Homo
sapiens]
Length = 554
Score = 954 bits (2467), Expect = 0.0
Identities = 473/473 (100%), Positives = 473/473 (100%)
Query: 1 MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTN 60
MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTN
Sbjct: 1 MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTN 60
Query: 61 LWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS 120
LWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS
Sbjct: 61 LWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS 120
Query: 121 RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD 180
RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD
Sbjct: 121 RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD 180
Query: 181 NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA 240
NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA
Sbjct: 181 NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA 240
Query: 241 ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD 300
ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD
Sbjct: 241 ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD 300
Query: 301 VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP 360
VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP
Sbjct: 301 VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP 360
Query: 361 GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ 420
GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ
Sbjct: 361 GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ 420
Query: 421 SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYK 473
SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYK
Sbjct: 421 SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYK 473
>gi|222136607 tetratricopeptide repeat domain 26 isoform 3 [Homo
sapiens]
Length = 523
Score = 870 bits (2249), Expect = 0.0
Identities = 442/473 (93%), Positives = 442/473 (93%), Gaps = 31/473 (6%)
Query: 1 MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTN 60
MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLE
Sbjct: 1 MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLE------------- 47
Query: 61 LWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS 120
EYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS
Sbjct: 48 ------------------EYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKS 89
Query: 121 RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD 180
RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD
Sbjct: 90 RLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLD 149
Query: 181 NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA 240
NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA
Sbjct: 150 NREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEA 209
Query: 241 ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD 300
ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD
Sbjct: 210 ELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDD 269
Query: 301 VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP 360
VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP
Sbjct: 270 VQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIP 329
Query: 361 GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ 420
GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ
Sbjct: 330 GRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQ 389
Query: 421 SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYK 473
SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYK
Sbjct: 390 SEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYK 442
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 27/155 (17%)
Query: 68 FHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNRLL 127
F LG +K A+E Y A K + E+ NL Y +L + +A+ +L N L
Sbjct: 112 FLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQ--------DQLHNAL- 162
Query: 128 FHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLAL 187
+ N D+T + L IH + +AI++YK+ + + E L
Sbjct: 163 ----------------NLNRHDLT--YIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTEL 204
Query: 188 NVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIAL 222
+ L Y +L Y + E L L P + A+
Sbjct: 205 LTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAI 239
Score = 30.4 bits (67), Expect = 3.8
Identities = 16/52 (30%), Positives = 27/52 (51%)
Query: 59 TNLWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQA 110
T + +G GD +A+E Y+ A + N+E+ L Y LG+Y++A
Sbjct: 170 TYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKA 221
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 34.3 bits (77), Expect = 0.26
Identities = 29/138 (21%), Positives = 56/138 (40%), Gaps = 24/138 (17%)
Query: 45 LLEFKRHVGEEEEDTNLWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFL 104
L E K+ +E+E +G A+ D+ AL+ Y+ A + + N N A YF
Sbjct: 218 LPENKKQALKEKE-----LGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEK 272
Query: 105 GMYKQAEAAGFKASKSRLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMR 164
G Y + KA + +NR ++ + + + + + ++
Sbjct: 273 GDYNKCRELCEKAIEVGRENR-------------------EDYRQIAKAYARIGNSYFKE 313
Query: 165 SHYQEAIDIYKRILLDNR 182
Y++AI Y + L ++R
Sbjct: 314 EKYKDAIHFYNKSLAEHR 331
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 33.9 bits (76), Expect = 0.34
Identities = 57/276 (20%), Positives = 108/276 (39%), Gaps = 40/276 (14%)
Query: 47 EFKRHVGEEEEDTNLWIGYCAFHLG--DYKRALEEYENATK-----EENCNSEVWVNLAC 99
+F R V + LW+ Y AFHL + ++A E A K EE VWV L
Sbjct: 1607 DFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLN 1666
Query: 100 TYFFLGMYKQAEAAGFKASKSRLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLAS 159
MY E+ +F A ++N+ K+ L LA
Sbjct: 1667 LE---NMYGSQESL-----------TKVFERAVQYNEPLKVF-------------LHLAD 1699
Query: 160 IHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDST 219
I+ +QEA ++Y R+L R+ A+ + + S VL L+ +P
Sbjct: 1700 IYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKE 1759
Query: 220 IALNLKACNHFRLYNGRAAEAE-LKSLMDNASSSFEFAKEL--IRHNLVVFRGGEGALQV 276
++ F + +AE K++ +N S++ ++ + ++ + G + ++
Sbjct: 1760 ---HVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRD 1816
Query: 277 LPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLE 312
+ V + A + ++ R D ++ + KD++
Sbjct: 1817 IFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQ 1852
>gi|31317299 inhibitor of DNA binding 1 isoform a [Homo sapiens]
Length = 155
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 249 ASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLI 308
AS + E + L ++ + R GA LP L+D E ++N+++Y D+ Y+ +
Sbjct: 25 ASGAGEVVRCLSEQSVAISRCAGGAGARLPALLD---EQQVNVLLY-----DMNGCYSRL 76
Query: 309 KDLEPTTPQ 317
K+L PT PQ
Sbjct: 77 KELVPTLPQ 85
>gi|31317297 inhibitor of DNA binding 1 isoform b [Homo sapiens]
Length = 149
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 249 ASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLI 308
AS + E + L ++ + R GA LP L+D E ++N+++Y D+ Y+ +
Sbjct: 25 ASGAGEVVRCLSEQSVAISRCAGGAGARLPALLD---EQQVNVLLY-----DMNGCYSRL 76
Query: 309 KDLEPTTPQ 317
K+L PT PQ
Sbjct: 77 KELVPTLPQ 85
>gi|225545550 TEL2, telomere maintenance 2, homolog [Homo sapiens]
Length = 837
Score = 32.3 bits (72), Expect = 1.00
Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 14/112 (12%)
Query: 228 NHFRLYNG---RAAEAELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVI 284
N+FRL R +A + SL SS F +++ V R E L VL P + +
Sbjct: 183 NYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQE-ILGVLVPRLAAL 241
Query: 285 PEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSR 336
+ YL Q + + L++ + P E +L G+V AALG E+ SR
Sbjct: 242 TQGS------YLHQ---RVCWRLVEQV-PDRAMEAVLTGLVEAALGPEVLSR 283
>gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens]
Length = 843
Score = 32.3 bits (72), Expect = 1.00
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 152 EDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVY 211
E L +A ++Y+ Y+EA++IY R+ LD+ A+ Y+L + +
Sbjct: 98 ESNLIMAKLNYVEGDYKEALNIYARVGLDDLPLTAVPP------YRLRVIAEAYATKGLC 151
Query: 212 LQQIPDSTIALNL 224
L+++P S+ NL
Sbjct: 152 LEKLPISSSTSNL 164
>gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]
Length = 1121
Score = 31.6 bits (70), Expect = 1.7
Identities = 21/78 (26%), Positives = 32/78 (41%)
Query: 59 TNLWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKAS 118
T L +G + L + A + A N N+EVW LA +G +AE A
Sbjct: 1035 TWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMI 1094
Query: 119 KSRLQNRLLFHLAHKFND 136
K +L++ L H +
Sbjct: 1095 KLKLKDEALLAEIHTLQE 1112
>gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo
sapiens]
Length = 515
Score = 31.6 bits (70), Expect = 1.7
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Query: 43 ITLLEFKRHVG---EEEEDTNLW--IGYCAFHLGDYKRALEEYENATKEENCNSEVWVNL 97
+TL F+R + EEE ++W +G+ A +GD A + + A N ++E + NL
Sbjct: 378 MTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNL 437
Query: 98 ACTYFFLGMYKQAEA 112
A G +QA A
Sbjct: 438 AVLEMRKGHVEQARA 452
Score = 30.8 bits (68), Expect = 2.9
Identities = 34/153 (22%), Positives = 61/153 (39%), Gaps = 22/153 (14%)
Query: 117 ASKSRLQNRLLFHLAHKFNDEKKLMSF------HQNLQDVTEDQLSLASIHYMRSHYQEA 170
+ K +L L ++ H ND K + H +D ++ + +Y Y+EA
Sbjct: 186 SQKPKLAKALFEYIFHHENDVKTALDLAALSTEHSQYKDWWW-KVQIGKCYYRLGMYREA 244
Query: 171 IDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHF 230
+K L +E + +Y+A Y LD + + L + P L C
Sbjct: 245 EKQFKSAL-KQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLL----CGIA 299
Query: 231 RLYNGRAAEAELKSLMDNASSSFEFAKELIRHN 263
R+Y M+N SS+ E+ KE+++ +
Sbjct: 300 RIYEE----------MNNMSSAAEYYKEVLKQD 322
Score = 30.8 bits (68), Expect = 2.9
Identities = 37/172 (21%), Positives = 65/172 (37%), Gaps = 9/172 (5%)
Query: 65 YCAFHLGDYKRALEEYENATKEENCNSEVW-VNLACTYFFLGMYKQAEAAGFKASKSRLQ 123
Y H D K AL+ +T+ W V + Y+ LGMY++AE A K +
Sbjct: 198 YIFHHENDVKTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM 257
Query: 124 NRLLFHLAHKF----NDEKKLMSFHQNLQDVTED---QLSLASIHYMRSHYQEAIDIYKR 176
+LA + L F Q L + +A I+ ++ A + YK
Sbjct: 258 VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKE 317
Query: 177 ILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQ-IPDSTIALNLKAC 227
+L + ++ + ++ D +++ LQ I + + NL C
Sbjct: 318 VLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLC 369
>gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo
sapiens]
Length = 475
Score = 31.6 bits (70), Expect = 1.7
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Query: 43 ITLLEFKRHVG---EEEEDTNLW--IGYCAFHLGDYKRALEEYENATKEENCNSEVWVNL 97
+TL F+R + EEE ++W +G+ A +GD A + + A N ++E + NL
Sbjct: 338 MTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNL 397
Query: 98 ACTYFFLGMYKQAEA 112
A G +QA A
Sbjct: 398 AVLEMRKGHVEQARA 412
Score = 30.8 bits (68), Expect = 2.9
Identities = 37/172 (21%), Positives = 65/172 (37%), Gaps = 9/172 (5%)
Query: 65 YCAFHLGDYKRALEEYENATKEENCNSEVW-VNLACTYFFLGMYKQAEAAGFKASKSRLQ 123
Y H D K AL+ +T+ W V + Y+ LGMY++AE A K +
Sbjct: 158 YIFHHENDVKTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM 217
Query: 124 NRLLFHLAHKF----NDEKKLMSFHQNLQDVTED---QLSLASIHYMRSHYQEAIDIYKR 176
+LA + L F Q L + +A I+ ++ A + YK
Sbjct: 218 VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKE 277
Query: 177 ILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQ-IPDSTIALNLKAC 227
+L + ++ + ++ D +++ LQ I + + NL C
Sbjct: 278 VLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLC 329
Score = 29.6 bits (65), Expect = 6.5
Identities = 34/149 (22%), Positives = 59/149 (39%), Gaps = 22/149 (14%)
Query: 121 RLQNRLLFHLAHKFNDEKKLMSF------HQNLQDVTEDQLSLASIHYMRSHYQEAIDIY 174
RL L ++ H ND K + H +D ++ + +Y Y+EA +
Sbjct: 150 RLGTALFEYIFHHENDVKTALDLAALSTEHSQYKDWWW-KVQIGKCYYRLGMYREAEKQF 208
Query: 175 KRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYN 234
K L +E + +Y+A Y LD + + L + P L C R+Y
Sbjct: 209 KSAL-KQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLL----CGIARIYE 263
Query: 235 GRAAEAELKSLMDNASSSFEFAKELIRHN 263
M+N SS+ E+ KE+++ +
Sbjct: 264 E----------MNNMSSAAEYYKEVLKQD 282
>gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo
sapiens]
Length = 505
Score = 31.6 bits (70), Expect = 1.7
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Query: 43 ITLLEFKRHVG---EEEEDTNLW--IGYCAFHLGDYKRALEEYENATKEENCNSEVWVNL 97
+TL F+R + EEE ++W +G+ A +GD A + + A N ++E + NL
Sbjct: 368 MTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNL 427
Query: 98 ACTYFFLGMYKQAEA 112
A G +QA A
Sbjct: 428 AVLEMRKGHVEQARA 442
Score = 30.8 bits (68), Expect = 2.9
Identities = 34/153 (22%), Positives = 61/153 (39%), Gaps = 22/153 (14%)
Query: 117 ASKSRLQNRLLFHLAHKFNDEKKLMSF------HQNLQDVTEDQLSLASIHYMRSHYQEA 170
+ K +L L ++ H ND K + H +D ++ + +Y Y+EA
Sbjct: 176 SQKPKLAKALFEYIFHHENDVKTALDLAALSTEHSQYKDWWW-KVQIGKCYYRLGMYREA 234
Query: 171 IDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHF 230
+K L +E + +Y+A Y LD + + L + P L C
Sbjct: 235 EKQFKSAL-KQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLL----CGIA 289
Query: 231 RLYNGRAAEAELKSLMDNASSSFEFAKELIRHN 263
R+Y M+N SS+ E+ KE+++ +
Sbjct: 290 RIYEE----------MNNMSSAAEYYKEVLKQD 312
Score = 30.8 bits (68), Expect = 2.9
Identities = 37/172 (21%), Positives = 65/172 (37%), Gaps = 9/172 (5%)
Query: 65 YCAFHLGDYKRALEEYENATKEENCNSEVW-VNLACTYFFLGMYKQAEAAGFKASKSRLQ 123
Y H D K AL+ +T+ W V + Y+ LGMY++AE A K +
Sbjct: 188 YIFHHENDVKTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM 247
Query: 124 NRLLFHLAHKF----NDEKKLMSFHQNLQDVTED---QLSLASIHYMRSHYQEAIDIYKR 176
+LA + L F Q L + +A I+ ++ A + YK
Sbjct: 248 VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKE 307
Query: 177 ILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQ-IPDSTIALNLKAC 227
+L + ++ + ++ D +++ LQ I + + NL C
Sbjct: 308 VLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLC 359
>gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens]
Length = 1316
Score = 31.6 bits (70), Expect = 1.7
Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 301 VQEAYNLIKDLEPTTPQEYI-LKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTI 359
V+ A L+K+L+P T Q ++ L+ + N L M ++ + Q +ASE + I
Sbjct: 1101 VRTAEKLLKELKPQTVQGHVQLRIMENYCL---MATKQKSNVEQALNTFTEIAASEKEHI 1157
Query: 360 PGRQCMASCFFLLKQ 374
P MA+ + +LKQ
Sbjct: 1158 PALLGMATAYMILKQ 1172
Score = 29.6 bits (65), Expect = 6.5
Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 11/155 (7%)
Query: 71 GDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNRLLFHL 130
GD +RAL +N T E+ E +A Y K F+ R+ N F L
Sbjct: 668 GDIERALSILQNVTAEQPYFIEAREKMADIYLKHRKDKMLYITCFREIAERMANPRSFLL 727
Query: 131 -----AHKFNDEKKLMSFHQNLQDVTEDQLSLASI--HYMRSH-YQEAIDIYKRIL-LDN 181
+ E+ ++++ Q L +D + + +++H Y AI Y+ L
Sbjct: 728 LGDAYMNILEPEEAIVAYEQALNQNPKDGTLASKMGKALIKTHNYSMAITYYEAALKTGQ 787
Query: 182 REYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIP 216
+ YL + +A KL +YD +++VL L P
Sbjct: 788 KNYLCYD--LAELLLKLKWYDKAEKVLQHALAHEP 820
>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
Length = 1564
Score = 31.2 bits (69), Expect = 2.2
Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 16/146 (10%)
Query: 72 DYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNRL----- 126
+YK AL+ + K+E N WV + L QA++A KA++ L
Sbjct: 21 EYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGL 80
Query: 127 --LFHLAHKFNDEKKLMSFHQNLQDVTEDQ---------LSLASIHYMRSHYQEAIDIYK 175
L+ + N + L +Q L D+ E L ++Y + E +
Sbjct: 81 ANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLYYQEKKHLEVARTWH 140
Query: 176 RILLDNREYLALNVYVALCYYKLDYY 201
+++ +E A N + + KL +
Sbjct: 141 KLIKTRQEQGAENEELHQLWRKLTQF 166
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 30.4 bits (67), Expect = 3.8
Identities = 33/158 (20%), Positives = 61/158 (38%), Gaps = 28/158 (17%)
Query: 70 LGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNR-LLF 128
+G + A+++Y++A S + N YF + QA KA K +N +L
Sbjct: 1455 MGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLM 1514
Query: 129 HLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALN 188
+ A KK ++ +V E A++++ R+H+
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHF--------------------- 1553
Query: 189 VYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKA 226
YY L Y++++E L L P+ + N +A
Sbjct: 1554 ------YYCLKQYELAEEDLNKALSLKPNDALVYNFRA 1585
>gi|169161714 PREDICTED: tetratricopeptide repeat domain 34 [Homo
sapiens]
Length = 747
Score = 30.4 bits (67), Expect = 3.8
Identities = 9/23 (39%), Positives = 17/23 (73%)
Query: 64 GYCAFHLGDYKRALEEYENATKE 86
G+CA H GD +RA+E+++ ++
Sbjct: 422 GFCALHAGDSRRAMEDFQTVVEQ 444
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 30.4 bits (67), Expect = 3.8
Identities = 33/158 (20%), Positives = 61/158 (38%), Gaps = 28/158 (17%)
Query: 70 LGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNR-LLF 128
+G + A+++Y++A S + N YF + QA KA K +N +L
Sbjct: 1455 MGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLM 1514
Query: 129 HLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALN 188
+ A KK ++ +V E A++++ R+H+
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHF--------------------- 1553
Query: 189 VYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKA 226
YY L Y++++E L L P+ + N +A
Sbjct: 1554 ------YYCLKQYELAEEDLNKALSLKPNDALVYNFRA 1585
>gi|169162130 PREDICTED: tetratricopeptide repeat domain 34 [Homo
sapiens]
Length = 901
Score = 30.4 bits (67), Expect = 3.8
Identities = 9/23 (39%), Positives = 17/23 (73%)
Query: 64 GYCAFHLGDYKRALEEYENATKE 86
G+CA H GD +RA+E+++ ++
Sbjct: 576 GFCALHAGDSRRAMEDFQTVVEQ 598
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 30.4 bits (67), Expect = 3.8
Identities = 33/158 (20%), Positives = 61/158 (38%), Gaps = 28/158 (17%)
Query: 70 LGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNR-LLF 128
+G + A+++Y++A S + N YF + QA KA K +N +L
Sbjct: 1455 MGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLM 1514
Query: 129 HLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALN 188
+ A KK ++ +V E A++++ R+H+
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHF--------------------- 1553
Query: 189 VYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKA 226
YY L Y++++E L L P+ + N +A
Sbjct: 1554 ------YYCLKQYELAEEDLNKALSLKPNDALVYNFRA 1585
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 30.4 bits (67), Expect = 3.8
Identities = 24/94 (25%), Positives = 42/94 (44%)
Query: 166 HYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLK 225
+Y++A+ Y L N + A+ ALCY KL ++ +++ LQ + A +
Sbjct: 638 NYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRR 697
Query: 226 ACNHFRLYNGRAAEAELKSLMDNASSSFEFAKEL 259
A H L N + + +L ++ S E EL
Sbjct: 698 ALAHKGLKNYQKSLIDLNKVILLDPSIIEAKMEL 731
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 30.4 bits (67), Expect = 3.8
Identities = 24/94 (25%), Positives = 42/94 (44%)
Query: 166 HYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLK 225
+Y++A+ Y L N + A+ ALCY KL ++ +++ LQ + A +
Sbjct: 638 NYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRR 697
Query: 226 ACNHFRLYNGRAAEAELKSLMDNASSSFEFAKEL 259
A H L N + + +L ++ S E EL
Sbjct: 698 ALAHKGLKNYQKSLIDLNKVILLDPSIIEAKMEL 731
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 30.0 bits (66), Expect = 4.9
Identities = 15/47 (31%), Positives = 24/47 (51%)
Query: 64 GYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQA 110
G F GDY++A E Y+ A + ++ +E N+ TY L +A
Sbjct: 500 GNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEA 546
>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
sapiens]
Length = 824
Score = 30.0 bits (66), Expect = 4.9
Identities = 15/47 (31%), Positives = 24/47 (51%)
Query: 64 GYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQA 110
G F GDY++A E Y+ A + ++ +E N+ TY L +A
Sbjct: 491 GNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEA 537
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 30.0 bits (66), Expect = 4.9
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 71 GDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNRLLFHL 130
G++K+A+E+Y + N S + N A Y L Y +A +A K +N F+
Sbjct: 207 GNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFY- 265
Query: 131 AHKFNDEKKLMSFHQNLQDVT 151
+ K L + + D++
Sbjct: 266 -RRAQAHKALKDYKSSFADIS 285
>gi|166235180 tetratricopeptide repeat domain 22 isoform 1 [Homo
sapiens]
Length = 569
Score = 30.0 bits (66), Expect = 4.9
Identities = 17/50 (34%), Positives = 23/50 (46%)
Query: 63 IGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEA 112
+G AF+L + A E + E N W NLA Y LG ++ EA
Sbjct: 72 LGAFAFYLEELDEARECFLEVAHEHPGNLNAWANLAHVYGRLGQEEEEEA 121
>gi|153792103 tetratricopeptide repeat domain 22 isoform 2 [Homo
sapiens]
Length = 372
Score = 30.0 bits (66), Expect = 4.9
Identities = 17/50 (34%), Positives = 23/50 (46%)
Query: 63 IGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEA 112
+G AF+L + A E + E N W NLA Y LG ++ EA
Sbjct: 72 LGAFAFYLEELDEARECFLEVAHEHPGNLNAWANLAHVYGRLGQEEEEEA 121
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 29.6 bits (65), Expect = 6.5
Identities = 11/42 (26%), Positives = 23/42 (54%)
Query: 137 EKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRIL 178
++ L H + VT +L +++ + HY+EA+ +YK +
Sbjct: 592 DENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAI 633
>gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X
chromosome [Homo sapiens]
Length = 1401
Score = 29.3 bits (64), Expect = 8.4
Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 28/149 (18%)
Query: 53 GEEEEDTNLWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVN------LACTYFFLGM 106
G+ E D +G+ L DY +AL Y+ + + S+ W N L YF
Sbjct: 89 GKVESDFFCQLGHFNLLLEDYPKALSAYQ---RYYSLQSDYWKNAAFLYGLGLVYFHYNA 145
Query: 107 YKQA----------EAAGFKASKSRLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLS 156
++ A + + +A + L+ L+F + + E L F L D LS
Sbjct: 146 FQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVNTDY--ESSLKHFQLALVDCNPCTLS 203
Query: 157 LASIHYMRSH-------YQEAIDIYKRIL 178
A I + +H Y A + Y+++L
Sbjct: 204 NAEIQFHIAHLYETQRKYHSAKEAYEQLL 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,614,069
Number of Sequences: 37866
Number of extensions: 747753
Number of successful extensions: 1836
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1786
Number of HSP's gapped (non-prelim): 58
length of query: 487
length of database: 18,247,518
effective HSP length: 106
effective length of query: 381
effective length of database: 14,233,722
effective search space: 5423048082
effective search space used: 5423048082
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.