Search of human proteins with 222136575

Search of human proteins with 222136575

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222136575 interleukin 10 receptor, alpha precursor [Homo
sapiens]
         (578 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222136575 interleukin 10 receptor, alpha precursor [Homo sapi...  1179   0.0  
gi|31083156 interleukin 20 receptor, alpha [Homo sapiens]              59   2e-08
gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens]    57   6e-08
gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens]    52   2e-06
gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens]    49   2e-05
gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens]      44   4e-04
gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]     42   0.001
gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens]            41   0.003
gi|71274152 hypothetical protein LOC388939 [Homo sapiens]              37   0.050
gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens]      35   0.25 
gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]       34   0.32 
gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]            34   0.42 
gi|56549696 E1A binding protein p400 [Homo sapiens]                    34   0.42 
gi|157504499 ankyrin repeat domain 47 [Homo sapiens]                   34   0.42 
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol...    33   0.55 
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    33   0.55 
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             33   0.55 
gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens]       33   0.55 
gi|113419423 PREDICTED: similar to forkhead box L2 [Homo sapiens]      33   0.72 
gi|169172132 PREDICTED: similar to forkhead box L2 [Homo sapiens]      33   0.94 
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa...    32   1.2  
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               32   1.2  
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               32   1.2  
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               32   1.2  
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 32   1.6  
gi|51479192 ring finger protein 1 [Homo sapiens]                       32   1.6  
gi|156104872 Ets2 repressor factor [Homo sapiens]                      32   1.6  
gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]                   32   2.1  
gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]                  32   2.1  
gi|149944526 additional sex combs like 3 [Homo sapiens]                32   2.1  

>gi|222136575 interleukin 10 receptor, alpha precursor [Homo
           sapiens]
          Length = 578

 Score = 1179 bits (3050), Expect = 0.0
 Identities = 578/578 (100%), Positives = 578/578 (100%)

Query: 1   MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVA 60
           MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVA
Sbjct: 1   MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVA 60

Query: 61  LLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSV 120
           LLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSV
Sbjct: 61  LLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSV 120

Query: 121 DEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTF 180
           DEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTF
Sbjct: 121 DEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTF 180

Query: 181 THKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISLTRQYFTVTNVIIFF 240
           THKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISLTRQYFTVTNVIIFF
Sbjct: 181 THKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISLTRQYFTVTNVIIFF 240

Query: 241 AFVLLLSGALAYCLALQLYVRRRKKLPSVLLFKKPSPFIFISQRPSPETQDTIHPLDEEA 300
           AFVLLLSGALAYCLALQLYVRRRKKLPSVLLFKKPSPFIFISQRPSPETQDTIHPLDEEA
Sbjct: 241 AFVLLLSGALAYCLALQLYVRRRKKLPSVLLFKKPSPFIFISQRPSPETQDTIHPLDEEA 300

Query: 301 FLKVSPELKNLDLHGSTDSGFGSTKPSLQTEEPQFLLPDPHPQADRTLGNREPPVLGDSC 360
           FLKVSPELKNLDLHGSTDSGFGSTKPSLQTEEPQFLLPDPHPQADRTLGNREPPVLGDSC
Sbjct: 301 FLKVSPELKNLDLHGSTDSGFGSTKPSLQTEEPQFLLPDPHPQADRTLGNREPPVLGDSC 360

Query: 361 SSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGS 420
           SSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGS
Sbjct: 361 SSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGS 420

Query: 421 ALGHHSPPEPEVPGEEDPAAVAFQGYLRQTRCAEEKATKTGCLEEESPLTDGLGPKFGRC 480
           ALGHHSPPEPEVPGEEDPAAVAFQGYLRQTRCAEEKATKTGCLEEESPLTDGLGPKFGRC
Sbjct: 421 ALGHHSPPEPEVPGEEDPAAVAFQGYLRQTRCAEEKATKTGCLEEESPLTDGLGPKFGRC 480

Query: 481 LVDEAGLHPPALAKGYLKQDPLEMTLASSGAPTGQWNQPTEEWSLLALSSCSDLGISDWS 540
           LVDEAGLHPPALAKGYLKQDPLEMTLASSGAPTGQWNQPTEEWSLLALSSCSDLGISDWS
Sbjct: 481 LVDEAGLHPPALAKGYLKQDPLEMTLASSGAPTGQWNQPTEEWSLLALSSCSDLGISDWS 540

Query: 541 FAHDLAPLGCVAAPGGLLGSFNSDLVTLPLISSLQSSE 578
           FAHDLAPLGCVAAPGGLLGSFNSDLVTLPLISSLQSSE
Sbjct: 541 FAHDLAPLGCVAAPGGLLGSFNSDLVTLPLISSLQSSE 578


>gi|31083156 interleukin 20 receptor, alpha [Homo sapiens]
          Length = 553

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 67/282 (23%), Positives = 117/282 (41%), Gaps = 20/282 (7%)

Query: 3   PCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPN-QSESTCYEVAL 61
           P L++LLAA     +   + G  LP P ++ F +    ++L WTP    Q     Y V  
Sbjct: 16  PLLLLLLAAPWGRAVPCVSGG--LPKPANITFLSINMKNVLQWTPPEGLQGVKVTYTVQY 73

Query: 62  LRYGIESWNSISNCSQ-TLSY-DLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFS 119
             YG + W + S C     +Y DL+A T D  H   Y A+V+A+ G++ S W  +   + 
Sbjct: 74  FIYGQKKWLNKSECRNINRTYCDLSAETSDYEHQ--YYAKVKAIWGTKCSKWAESGRFYP 131

Query: 120 VDEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPAND---TYESIFSHFREYEIAIRKVPG 176
             E  +    V L      I   +  P        D   + + I+S+ + Y +++     
Sbjct: 132 FLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSNLK-YNVSVLNTKS 190

Query: 177 NFTFTHKKVKHENFSLLTSGEVGE-FCVQVKPSVASRSNKGMWSKEECISLTRQYFTVTN 235
           N T++     H    +LT  E    +CV V+  V     +   S+++C    +   +   
Sbjct: 191 NRTWSQCVTNHT--LVLTWLEPNTLYCVHVESFVPGPPRRAQPSEKQCARTLKDQSSEFK 248

Query: 236 VIIFFAFVL------LLSGALAYCLALQLYVRRRKKLPSVLL 271
             I F +VL       L   + Y +   ++V + K   +++L
Sbjct: 249 AKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLIL 290


>gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens]
          Length = 231

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 58/238 (24%), Positives = 95/238 (39%), Gaps = 20/238 (8%)

Query: 1   MLP--CLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTP-IPNQSESTCY 57
           M+P  C +  L +     +       E   P  V F++  FH+IL W P       S+ Y
Sbjct: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60

Query: 58  EVALLRYGIESWNSISNC--SQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTN 115
            V    YG   W +  +C  +Q LS DLT+ T D+     Y  RVRA     +S W++T 
Sbjct: 61  FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDI--QEPYYGRVRAASAGSYSEWSMTP 118

Query: 116 TRFSVDEVTLTVGSVNLEIHNGFILGKIQLP-------RPKMAPANDTYESIFSHFREYE 168
                 E  +    +N+   NG +L  +  P       + K     D YE ++  F    
Sbjct: 119 RFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVF-IIN 177

Query: 169 IAIRKVPGNFTFTHKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISL 226
            ++ K    +   H+ V+ E  +  +S     +CV  +        +   S+E C+ +
Sbjct: 178 NSLEKEQKVYEGAHRAVEIEALTPHSS-----YCVVAEIYQPMLDRRSQRSEERCVEI 230


>gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens]
          Length = 130

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 7/119 (5%)

Query: 1   MLP--CLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTP-IPNQSESTCY 57
           M+P  C +  L +     +       E   P  V F++  FH+IL W P       S+ Y
Sbjct: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60

Query: 58  EVALLRYGIESWNSISNC--SQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVT 114
            V    YG   W +  +C  +Q LS DLT+ T D+     Y  RVRA     +S W++T
Sbjct: 61  FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDI--QEPYYGRVRAASAGSYSEWSMT 117


>gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens]
          Length = 263

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 59/270 (21%), Positives = 99/270 (36%), Gaps = 52/270 (19%)

Query: 1   MLP--CLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTP----------- 47
           M+P  C +  L +     +       E   P  V F++  FH+IL W P           
Sbjct: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60

Query: 48  -------------IPNQSESTCYEV---------ALLRYGIESWNSISNC--SQTLSYDL 83
                          +Q  S C++           L +YG   W +  +C  +Q LS DL
Sbjct: 61  FVQYKIMFSCSMKSSHQKPSGCWQHISCNFPGCRTLAKYGQRQWKNKEDCWGTQELSCDL 120

Query: 84  TAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSVDEVTLTVGSVNLEIHNGFILGKI 143
           T+ T D+     Y  RVRA     +S W++T       E  +    +N+   NG +L  +
Sbjct: 121 TSETSDIQEP--YYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVIL 178

Query: 144 QLP-------RPKMAPANDTYESIFSHFREYEIAIRKVPGNFTFTHKKVKHENFSLLTSG 196
             P       + K     D YE ++  F     ++ K    +   H+ V+ E  +  +S 
Sbjct: 179 HAPNLPYRYQKEKNVSIEDYYELLYRVF-IINNSLEKEQKVYEGAHRAVEIEALTPHSS- 236

Query: 197 EVGEFCVQVKPSVASRSNKGMWSKEECISL 226
               +CV  +        +   S+E C+ +
Sbjct: 237 ----YCVVAEIYQPMLDRRSQRSEERCVEI 262


>gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens]
          Length = 311

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 61/249 (24%), Positives = 100/249 (40%), Gaps = 31/249 (12%)

Query: 26  LPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVALLR-----YGIESWNSISNCSQTLS 80
           LP+P ++   +    H+L W+P+    E+  Y V         Y    W   S CS T  
Sbjct: 35  LPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEG 94

Query: 81  YDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSVDEVTLTVGSVNLEIHNGFIL 140
            +   VT D+  +  Y  RVRA  GS+ S W++    F+ +   LT   + +   +GF L
Sbjct: 95  PECD-VTDDITATVPYNLRVRATLGSQTSAWSILKHPFNRNSTILTRPGMEI-TKDGFHL 152

Query: 141 GKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTFTHKKVKHEN---FSLLTSGE 197
             I+L            E +   F       R+ PG     H K+         L T   
Sbjct: 153 -VIEL------------EDLGPQFEFLVAYWRREPG--AEEHVKMVRSGGIPVHLETMEP 197

Query: 198 VGEFCVQVKPSVASRSNKGMWSKEECISLTRQYFTVTNVIIFFAFVLLLSGALAYCLALQ 257
              +CV+ +  V +      +S+ EC+ +  Q   +  V+  FAFV    G +   + + 
Sbjct: 198 GAAYCVKAQTFVKAIGRYSAFSQTECVEV--QGEAIPLVLALFAFV----GFMLILVVVP 251

Query: 258 LYVRRRKKL 266
           L+V +  +L
Sbjct: 252 LFVWKMGRL 260


>gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]
          Length = 325

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/244 (22%), Positives = 98/244 (40%), Gaps = 15/244 (6%)

Query: 26  LPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVALLRYGIESWNSISNCSQTLSYDLTA 85
           +P P +V   +  F +IL W        +  +    L Y I        C  T   +   
Sbjct: 21  VPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQ----DKCMNTTLTECDF 76

Query: 86  VTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSVDEVTLTVGSVNLEIHNGFILGKIQL 145
            +L  Y    +  RVRA     HS+W V  T   VD+  +    + +E+    +  +   
Sbjct: 77  SSLSKY--GDHTLRVRAEFADEHSDW-VNITFCPVDDTIIGPPGMQVEVLADSLHMRFLA 133

Query: 146 PRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTFTHKKVKHENFSLLTSGEVGE-FCVQ 204
           P+ +      T +++++ +  Y +   K   +  F  +     +F +L + E    +CVQ
Sbjct: 134 PKIENEYETWTMKNVYNSWT-YNVQYWKNGTDEKF--QITPQYDFEVLRNLEPWTTYCVQ 190

Query: 205 VKPSVASRSNKGMWSKEECISLTRQYFTVTN---VIIFFAFVLLLSGALAYCLALQLYVR 261
           V+  +  R+  G WS+  C   T    TV +    +I  A V ++  AL  C AL   V 
Sbjct: 191 VRGFLPDRNKAGEWSEPVCEQTTHDE-TVPSWMVAVILMASVFMVCLALLGCFALLWCVY 249

Query: 262 RRKK 265
           ++ K
Sbjct: 250 KKTK 253


>gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens]
          Length = 574

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 7/119 (5%)

Query: 12  LLSLRLGS-DAHGTELPSP--PSVWFEAEFFHHILHWTPIPNQSESTCYEVALLRYGIES 68
           L  L +GS  AH  E PS     V F++  F +IL W   P  +  T Y +    YG   
Sbjct: 5   LTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTYGERD 64

Query: 69  WNSISNCSQTL--SYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSVDEVTL 125
           W +   C +    S +LT  T +L  +  Y ARV AV     S   +T+   S+   TL
Sbjct: 65  WVAKKGCQRITRKSCNLTVETGNL--TELYYARVTAVSAGGRSATKMTDRFSSLQHTTL 121


>gi|71274152 hypothetical protein LOC388939 [Homo sapiens]
          Length = 1288

 Score = 37.0 bits (84), Expect = 0.050
 Identities = 53/197 (26%), Positives = 77/197 (39%), Gaps = 37/197 (18%)

Query: 272  FKKPSPFIFISQRPSPETQDTIHPLDEEAFL-KVSPELKNLDLHGSTDSGFGSTKPSLQT 330
            F  PSP   +S  PS E ++T    D +A + KVS    ++    +  S     KP L T
Sbjct: 1084 FSIPSPSPPMS--PSQEHKETRDSEDSQAVIAKVSGNTHSIFCPAT--SSLFEAKPPLST 1139

Query: 331  EEPQFLLPDPHPQADRTLGNRE--------PPVLGDS------CSSG-------SSNSTD 369
              P    P   P+A   LGN          P +  DS      C+         +++   
Sbjct: 1140 AHP-LTPPSLPPEAGGPLGNPAECWKNSSGPWLRADSQRRAALCALNPLPFLRRTASDRQ 1198

Query: 370  SGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGS--------- 420
             G   Q P+L P T  ++E Q+G NS  ++    D    S   + + QGG+         
Sbjct: 1199 PGGRPQPPTLDP-TSTSYESQLGQNSSSEESPKKDTEPGSSPCSPELQGGTRRASPPEFC 1257

Query: 421  ALGHHSPPEPEVPGEED 437
             LGH   PEP     +D
Sbjct: 1258 VLGHGLQPEPRTGHIQD 1274


>gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens]
          Length = 632

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 4/111 (3%)

Query: 384 GPTWEQQVGSNSRG-QDDSGIDLVQNSEGR-AGDTQGGSALGHHSPPEPEVPGEEDPAAV 441
           GP  E   G  + G Q  SG   +  ++GR A D+ G  A G   P  P  PG+E P  +
Sbjct: 133 GPKREGPRGPRAGGAQGPSGPSELPAAQGRLAPDSAGEGAPGREPPASPAPPGKEHPRDL 192

Query: 442 AFQGYLRQTRCAEEKATKTGCLEEES--PLTDGLGPKFGRCLVDEAGLHPP 490
            F      +        K  CL +E   P  + + P+  R  + + GL  P
Sbjct: 193 KFSIDYILSSPDPFPGLKPPCLAQEGRYPRLEKVSPQCQRQTLSKRGLPTP 243


>gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]
          Length = 557

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 44/229 (19%), Positives = 89/229 (38%), Gaps = 11/229 (4%)

Query: 1   MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVA 60
           +L    ++L A+    L + A G  L SP  V  +    + IL W        +  +   
Sbjct: 5   LLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFD 64

Query: 61  LLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSV 120
             + G+++W  +S C    S      +L L      + R+RA +    S+W   ++    
Sbjct: 65  YQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRA-EKENTSSWYEVDSFTPF 123

Query: 121 DEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTF 180
            +  +    V+LE  +  I+  I  P  K    +    ++      Y + I K   N + 
Sbjct: 124 RKAQIGPPEVHLEAEDKAIVIHIS-PGTK----DSVMWALDGLSFTYSLVIWK---NSSG 175

Query: 181 THKKVK--HENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISLT 227
             ++++  +    +        +C++VK ++ +    G++S   CI  T
Sbjct: 176 VEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTT 224



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 4   CLVVLLAALLSLRLG--SDAH------GTELPSPPSVWFEAEFFHHILHWT-PIPNQSES 54
           CL V  A L S ++G  S  H        ELP P ++    +  +++L W     N +  
Sbjct: 199 CLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQ 258

Query: 55  TCYEVALLRYG----IESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSN 110
             +  A L+      +  W  I +C + +         +++    Y  RV+A DG+  S 
Sbjct: 259 VQWLHAFLKRNPGNHLYKWKQIPDC-ENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSF 317

Query: 111 WT 112
           W+
Sbjct: 318 WS 319


>gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 182

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 30/91 (32%), Positives = 33/91 (36%), Gaps = 23/91 (25%)

Query: 353 PPVLGDSCSSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGR 412
           PP L  S SS S +S  SG                    GS S GQ   G  L   S  R
Sbjct: 43  PPPLAPSSSSSSGSSGSSG------------------GGGSGSAGQPTLGSMLAVGSAAR 84

Query: 413 -----AGDTQGGSALGHHSPPEPEVPGEEDP 438
                AG   GG+AL    PP P +P    P
Sbjct: 85  RASERAGGRAGGTALRAREPPPPLLPPPSPP 115


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 9/116 (7%)

Query: 328 LQTEEPQFLLPDPHPQADRTLGNREPPVLGDSCSSGSSNSTDSGICLQEPSLSPSTGPTW 387
           +QT+ P    P P             P LG   SS +    D+ + +++ SLSPS+G  +
Sbjct: 131 VQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISLSPSSGGHF 190

Query: 388 EQQVGSN----SRG-----QDDSGIDLVQNSEGRAGDTQGGSALGHHSPPEPEVPG 434
             Q GS     ++G     Q       V+        TQ G  + H  P  P   G
Sbjct: 191 VFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAG 246


>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
          Length = 821

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 15/109 (13%)

Query: 377 PSLSPSTGPTWEQQVG--------SNSRGQDDS-------GIDLVQNSEGRAGDTQGGSA 421
           P   PS+GP   Q VG        S+S    DS       G +   +S G   D+ GGS 
Sbjct: 456 PGAQPSSGPKSLQFVGVLNGEYESSSSEDASDSDGDSENGGAEPPGSSSGSGDDSGGGSD 515

Query: 422 LGHHSPPEPEVPGEEDPAAVAFQGYLRQTRCAEEKATKTGCLEEESPLT 470
            G   PP      + +P A A    + Q RC      +  C+  +  L+
Sbjct: 516 SGTPGPPSGGDIRDPEPEAEAEPQQVAQGRCELSPRLREACVALQRQLS 564


>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1b
           [Homo sapiens]
          Length = 867

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 4/118 (3%)

Query: 326 PSLQTEEPQFLLPDPHPQADRTLGNREPPVLGDSCSSGSSNST-DSGICLQEPSLSPSTG 384
           P+      Q L   P PQ     G R  P  G   + G++ +  D  +     S S S G
Sbjct: 409 PAQAPTSSQELAGAPEPQGSCAQGGRVAP--GQRPAQGATGTDLDFDLSSDSESSSESEG 466

Query: 385 PTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGSALGHHSPPEPEVPGEEDPAAVA 442
            T      S+   +   G    + +   AG    GS+L    P  P +PGE +P A A
Sbjct: 467 -TKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSLPGEAEPGAHA 523


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 4/118 (3%)

Query: 326 PSLQTEEPQFLLPDPHPQADRTLGNREPPVLGDSCSSGSSNST-DSGICLQEPSLSPSTG 384
           P+      Q L   P PQ     G R  P  G   + G++ +  D  +     S S S G
Sbjct: 409 PAQAPTSSQELAGAPEPQGSCAQGGRVAP--GQRPAQGATGTDLDFDLSSDSESSSESEG 466

Query: 385 PTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGSALGHHSPPEPEVPGEEDPAAVA 442
            T      S+   +   G    + +   AG    GS+L    P  P +PGE +P A A
Sbjct: 467 -TKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSLPGEAEPGAHA 523


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 6/59 (10%)

Query: 311 LDLHGSTDSGFGSTKPSLQTEEPQFLLP-DPHPQADRTLGNREPPVLGDSCSSGSSNST 368
           L L+  TDSG+GS  PSL++     +LP  P P      G+      G +CSS SS+S+
Sbjct: 102 LSLYSETDSGYGSYTPSLKSPNGVRVLPMVPAPP-----GSSAAAARGAACSSLSSSSS 155


>gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens]
          Length = 1024

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 56/225 (24%), Positives = 72/225 (32%), Gaps = 22/225 (9%)

Query: 345 DRTLGNREPPVLGDSCSSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGID 404
           D  L  RE     DS      +S         P+  P   P     +GS +  +DD    
Sbjct: 302 DEVLAEREE---ADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAG 358

Query: 405 LVQNSEGRAGDTQGGSALGHHSP---PEPEVPGEE------DPAAVAFQGYLRQTRCAEE 455
             ++ +    +   G+  G   P   P P +PG        D  +  F+  L   R    
Sbjct: 359 GEEDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGT 418

Query: 456 KATKTGCLEE-ESPLTDGLGPKFGRCLVDEAGLHPPALAK---GYLKQDPLEMTLASSGA 511
             T    LE   SP     GP        E    PPA            PLE    +S A
Sbjct: 419 SYTSLASLEALASP-----GPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSA 473

Query: 512 PTGQWNQPTEEWSLLALSSCSDLGISDWSFAHDLAPLGCVAAPGG 556
             G W Q  EE    A +  +  G    S  H    LG  AAP G
Sbjct: 474 ADGPWTQRGEEEEAEARAKLAP-GREPPSPCHSEDSLGLGAAPLG 517


>gi|113419423 PREDICTED: similar to forkhead box L2 [Homo sapiens]
          Length = 387

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 4/107 (3%)

Query: 384 GPTWEQQVGSNSRG-QDDSGIDLVQNSEGR-AGDTQGGSALGHHSPPEPEVPGEEDPAAV 441
           GP  E   G  + G Q  SG      ++GR A D+ G  A G   P  P  PG+E P  +
Sbjct: 195 GPKREGPRGPRAGGAQGPSGPSEPPAAQGRLAPDSAGEGAPGREPPASPAPPGKEHPRDL 254

Query: 442 AFQGYLRQTRCAEEKATKTGCLEEES--PLTDGLGPKFGRCLVDEAG 486
            F      +        K  CL +E   P  + +GP F      ++G
Sbjct: 255 KFSIDYILSSPDPFPGLKPPCLAQEGRYPRLEKVGPHFWTIWKQDSG 301


>gi|169172132 PREDICTED: similar to forkhead box L2 [Homo sapiens]
          Length = 528

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 384 GPTWEQQVGSNSRG-QDDSGIDLVQNSEGR-AGDTQGGSALGHHSPPEPEVPGEEDPAAV 441
           GP  E   G  + G Q  SG      ++GR A D+ G  A G   P  P  PG+E P  +
Sbjct: 428 GPKREGPRGPRAGGAQGPSGPSEPPAAQGRLAPDSAGEGAPGREPPASPAPPGKEHPRDL 487

Query: 442 AFQGYLRQTRCAEEKATKTGCLEEES--PLTDGLGPKF 477
            F      +        K  CL +E   P  + +GP F
Sbjct: 488 KFSIDYILSSPDPFPGLKPPCLAQEGRYPRLEKVGPHF 525


>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
           sapiens]
          Length = 1067

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 3/64 (4%)

Query: 363 GSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGSAL 422
           G S   +SG C  E         +W  + G     +++ G  L  NS GR+ DT  G   
Sbjct: 476 GRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSG--- 532

Query: 423 GHHS 426
           GH S
Sbjct: 533 GHSS 536


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 352 EPPVLGDSCSSGSSNSTDSGICLQEPSLSP--STGPTWEQQVGSNSRGQDDSGIDLVQNS 409
           +PP+   + SSG++ ST S      PS+ P  S+GPT  +     S     + +      
Sbjct: 17  QPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGG 76

Query: 410 EGRAGDTQGGSALGH 424
            G  G   GG + G+
Sbjct: 77  GGGGGSGGGGGSSGN 91


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 352 EPPVLGDSCSSGSSNSTDSGICLQEPSLSP--STGPTWEQQVGSNSRGQDDSGIDLVQNS 409
           +PP+   + SSG++ ST S      PS+ P  S+GPT  +     S     + +      
Sbjct: 17  QPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGG 76

Query: 410 EGRAGDTQGGSALGH 424
            G  G   GG + G+
Sbjct: 77  GGGGGSGGGGGSSGN 91


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 352 EPPVLGDSCSSGSSNSTDSGICLQEPSLSP--STGPTWEQQVGSNSRGQDDSGIDLVQNS 409
           +PP+   + SSG++ ST S      PS+ P  S+GPT  +     S     + +      
Sbjct: 17  QPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGG 76

Query: 410 EGRAGDTQGGSALGH 424
            G  G   GG + G+
Sbjct: 77  GGGGGSGGGGGSSGN 91


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 14/103 (13%)

Query: 427 PPEPEVPGEEDPAAVAFQGYLRQTRCAEEKATKTGCLEEESPLT------DGLGPKFGRC 480
           PP+ +VPG    A VA Q  +        K  K G     SP+T       G+GP F + 
Sbjct: 269 PPQYQVPGNLSAAQVAAQNAVEAA-----KNQKAGLGPRFSPITPLQQAAPGVGPPFSQA 323

Query: 481 LVDEAGLHPPALAKGYLKQDPLEMTLASSG---APTGQWNQPT 520
              +    PP   K      P  ++  + G   APT Q   P+
Sbjct: 324 PAPQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPS 366


>gi|51479192 ring finger protein 1 [Homo sapiens]
          Length = 406

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 33/111 (29%), Positives = 40/111 (36%), Gaps = 22/111 (19%)

Query: 340 PHPQADRTL----GNREPPVLGDSCSSGSSNSTDSGICLQEPSLSPSTGPTWEQ------ 389
           P P +D+T     G  EP   G+    G   S+DS      P  +P   P   +      
Sbjct: 159 PIPGSDQTTTMSGGEGEP---GEGEGDGEDVSSDSA-----PDSAPGPAPKRPRGGGAGG 210

Query: 390 -QVGSNSRGQDDSGIDLVQNSEGRAGDTQGGSALGHHSP---PEPEVPGEE 436
             VG+   G    G        G  G T GG  LG  SP   P P  PG E
Sbjct: 211 SSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGE 261


>gi|156104872 Ets2 repressor factor [Homo sapiens]
          Length = 548

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 30/110 (27%), Positives = 40/110 (36%), Gaps = 16/110 (14%)

Query: 326 PSLQTEEPQFLLPDPHPQADRTLGNREPPVLGDSCSSGSSNSTDSGICLQEPSLSPSTGP 385
           P L   +PQ   PD  P     +    PPV   + SS SS+S+     LQ P L      
Sbjct: 335 PGLVVPQPQ--RPDKCPLPP--MAPETPPVPSSASSSSSSSSSPFKFKLQPPPL------ 384

Query: 386 TWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGSALGHHSPPEPEVPGE 435
                 G   R   +  +     S G AG    G+      PP P++  E
Sbjct: 385 ------GRRQRAAGEKAVAGADKSGGSAGGLAEGAGALAPPPPPPQIKVE 428


>gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]
          Length = 457

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 4/86 (4%)

Query: 361 SSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGS 420
           ++GS     +G    +  L  + GP  E   G+ S     S     ++  G  G+ +G  
Sbjct: 269 AAGSGKKAAAGAQASQAQLGEAAGPASETPAGTES--PHSSASPCQEHKRGGLGELKGTP 326

Query: 421 ALGHHSPPEP-EVPGEEDPAAVAFQG 445
           A    SPPEP   PG++  AA    G
Sbjct: 327 AAA-LSPPEPAPSPGQQQQAAAHLLG 351


>gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]
          Length = 463

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 4/86 (4%)

Query: 361 SSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGS 420
           ++GS     +G    +  L  + GP  E   G+ S     S     ++  G  G+ +G  
Sbjct: 275 AAGSGKKAAAGAQASQAQLGEAAGPASETPAGTES--PHSSASPCQEHKRGGLGELKGTP 332

Query: 421 ALGHHSPPEP-EVPGEEDPAAVAFQG 445
           A    SPPEP   PG++  AA    G
Sbjct: 333 AAA-LSPPEPAPSPGQQQQAAAHLLG 357


>gi|149944526 additional sex combs like 3 [Homo sapiens]
          Length = 2248

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 31/150 (20%), Positives = 56/150 (37%), Gaps = 13/150 (8%)

Query: 294  HPLDEEAFLKVSPELKNLDLHGSTDSGFGSTKPSLQTEEPQFLLP---DPHPQADRTLGN 350
            H + +    KV P    L +        G+  PS + ++ Q++      P  +  R   +
Sbjct: 866  HSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTH 925

Query: 351  REPPVLGDSCSSGSSNSTDSGICLQEPSLSPS--TGPTWEQQVGSNSRGQDDSGIDLVQN 408
            ++        +S +S S+       EPS SP      + + ++      +  S   + + 
Sbjct: 926  KQGSTQSRLETSHTSKSS-------EPSKSPDGIRNESRDSEISKRKTAEQHS-FGICKE 977

Query: 409  SEGRAGDTQGGSALGHHSPPEPEVPGEEDP 438
               R  D Q    +   SPPE E P  E+P
Sbjct: 978  KRARIEDDQSTRNISSSSPPEKEQPPREEP 1007


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,789,845
Number of Sequences: 37866
Number of extensions: 1342782
Number of successful extensions: 4027
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 3967
Number of HSP's gapped (non-prelim): 113
length of query: 578
length of database: 18,247,518
effective HSP length: 108
effective length of query: 470
effective length of database: 14,157,990
effective search space: 6654255300
effective search space used: 6654255300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.