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Search of human proteins with 22212922
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
(390 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 816 0.0
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 816 0.0
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 816 0.0
gi|22212918 ciliary neurotrophic factor receptor preproprotein [... 140 2e-33
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H... 140 2e-33
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi... 121 1e-27
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap... 119 4e-27
gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens] 96 4e-20
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 70 2e-12
gi|4506107 prolactin receptor [Homo sapiens] 67 2e-11
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 54 2e-07
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 53 4e-07
gi|24497438 interleukin 12B precursor [Homo sapiens] 50 3e-06
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 48 2e-05
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 45 9e-05
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 45 9e-05
gi|27437045 colony stimulating factor 3 receptor isoform d precu... 44 2e-04
gi|24496783 colony stimulating factor 3 receptor isoform c precu... 44 2e-04
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 44 2e-04
gi|4503081 colony stimulating factor 3 receptor isoform a precur... 44 2e-04
gi|156104903 myomesin 2 [Homo sapiens] 44 2e-04
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 44 3e-04
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 44 3e-04
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 44 3e-04
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 44 3e-04
gi|144226847 obscurin-like 1 [Homo sapiens] 43 6e-04
gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens] 43 6e-04
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 42 0.001
gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo ... 41 0.002
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 41 0.002
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 816 bits (2107), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF 60
MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF
Sbjct: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF 60
Query: 61 RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC 120
RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC
Sbjct: 61 RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC 120
Query: 121 QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC 180
QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC
Sbjct: 121 QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC 180
Query: 181 VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW 240
VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW
Sbjct: 181 VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW 240
Query: 241 TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD 300
TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD
Sbjct: 241 TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD 300
Query: 301 AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR 360
AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR
Sbjct: 301 AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR 360
Query: 361 DSVEQVAVLASLGILSFLGLVAGALALGLW 390
DSVEQVAVLASLGILSFLGLVAGALALGLW
Sbjct: 361 DSVEQVAVLASLGILSFLGLVAGALALGLW 390
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 816 bits (2107), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF 60
MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF
Sbjct: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF 60
Query: 61 RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC 120
RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC
Sbjct: 61 RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC 120
Query: 121 QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC 180
QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC
Sbjct: 121 QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC 180
Query: 181 VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW 240
VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW
Sbjct: 181 VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW 240
Query: 241 TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD 300
TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD
Sbjct: 241 TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD 300
Query: 301 AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR 360
AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR
Sbjct: 301 AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR 360
Query: 361 DSVEQVAVLASLGILSFLGLVAGALALGLW 390
DSVEQVAVLASLGILSFLGLVAGALALGLW
Sbjct: 361 DSVEQVAVLASLGILSFLGLVAGALALGLW 390
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 816 bits (2107), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF 60
MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF
Sbjct: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF 60
Query: 61 RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC 120
RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC
Sbjct: 61 RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC 120
Query: 121 QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC 180
QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC
Sbjct: 121 QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC 180
Query: 181 VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW 240
VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW
Sbjct: 181 VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW 240
Query: 241 TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD 300
TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD
Sbjct: 241 TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD 300
Query: 301 AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR 360
AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR
Sbjct: 301 AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR 360
Query: 361 DSVEQVAVLASLGILSFLGLVAGALALGLW 390
DSVEQVAVLASLGILSFLGLVAGALALGLW
Sbjct: 361 DSVEQVAVLASLGILSFLGLVAGALALGLW 390
>gi|22212918 ciliary neurotrophic factor receptor preproprotein
[Homo sapiens]
Length = 372
Score = 140 bits (354), Expect = 2e-33
Identities = 105/312 (33%), Positives = 148/312 (47%), Gaps = 26/312 (8%)
Query: 12 LVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGP 71
++A A A+V A PQ P VQY + G V L C V+W +G P
Sbjct: 12 VLAAAAAVVYAQRHSPQE--APHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDL---AP 66
Query: 72 DSGLGHELVLAQADSTDEGTYICQTLDG-ALGGTVTLQLGYPPARPVVSCQAADY-ENFS 129
D G +LVL + G Y C D L V L +G PP PV+SC++ Y + F
Sbjct: 67 DLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFY 126
Query: 130 CTWSPSQISGLPT-RYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFW 188
C+W LPT Y+ + TVL C +DP RC + +
Sbjct: 127 CSWH------LPTPTYIPNTFNVTVLHGSKIM--------VCEKDPALKNRCHIRYMHLF 172
Query: 189 S--QYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASW 246
S +Y+++++ N LG + + +I++PDPP+ + VP PRRL +W P++W
Sbjct: 173 STIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTW 232
Query: 247 PCQPHFLLKFRLQYRPAQHPAWSTVEPA-GLEEVITDAVAGLPHAVRVSARDFLDAGTWS 305
P F LKF L+YRP W VE + G ITDA AG + ++V+A+D + GTWS
Sbjct: 233 PDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD-NEIGTWS 291
Query: 306 TWSPEAWGTPST 317
WS A TP T
Sbjct: 292 DWSVAAHATPWT 303
>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
sapiens]
Length = 372
Score = 140 bits (354), Expect = 2e-33
Identities = 105/312 (33%), Positives = 148/312 (47%), Gaps = 26/312 (8%)
Query: 12 LVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGP 71
++A A A+V A PQ P VQY + G V L C V+W +G P
Sbjct: 12 VLAAAAAVVYAQRHSPQE--APHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDL---AP 66
Query: 72 DSGLGHELVLAQADSTDEGTYICQTLDG-ALGGTVTLQLGYPPARPVVSCQAADY-ENFS 129
D G +LVL + G Y C D L V L +G PP PV+SC++ Y + F
Sbjct: 67 DLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFY 126
Query: 130 CTWSPSQISGLPT-RYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFW 188
C+W LPT Y+ + TVL C +DP RC + +
Sbjct: 127 CSWH------LPTPTYIPNTFNVTVLHGSKIM--------VCEKDPALKNRCHIRYMHLF 172
Query: 189 S--QYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASW 246
S +Y+++++ N LG + + +I++PDPP+ + VP PRRL +W P++W
Sbjct: 173 STIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTW 232
Query: 247 PCQPHFLLKFRLQYRPAQHPAWSTVEPA-GLEEVITDAVAGLPHAVRVSARDFLDAGTWS 305
P F LKF L+YRP W VE + G ITDA AG + ++V+A+D + GTWS
Sbjct: 233 PDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD-NEIGTWS 291
Query: 306 TWSPEAWGTPST 317
WS A TP T
Sbjct: 292 DWSVAAHATPWT 303
>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
sapiens]
Length = 468
Score = 121 bits (303), Expect = 1e-27
Identities = 117/404 (28%), Positives = 172/404 (42%), Gaps = 44/404 (10%)
Query: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVS 58
++ C+ L+ +L A AL A CP GV PG SV L CPGV D V
Sbjct: 2 LAVGCALLAALLAAPGAAL--APRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVH 59
Query: 59 WFRDGEPKLLQGPD--SGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARP 116
W +P P +G+G L+L D G Y C G GTV L + PP P
Sbjct: 60 WVLR-KPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEP 117
Query: 117 VVSC-QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCP---- 171
+SC + + N C W P L T+ + RK A+ + PC
Sbjct: 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQE-------PCQYSQE 170
Query: 172 QDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESVP 230
V G S Y +++ + +G+ ++ IL+PDPP + V +V
Sbjct: 171 SQKFSCQLAVPEGDS--SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVA 228
Query: 231 GYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLP 288
PR L +W P SW + L+F L+YR + ++T L+ VI DA +GL
Sbjct: 229 RNPRWLSVTWQDPHSWNSS-FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLR 287
Query: 289 HAVRVSARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRP 348
H V++ A++ G WS WSPEA GTP T + P E +V +P
Sbjct: 288 HVVQLRAQEEFGQGEWSEWSPEAMGTPWTES------------RSPPAENEVSTPMQALT 335
Query: 349 SLQPHPRLLDHRDSVEQVAV----LASLGILSFLGLVAGALALG 388
+ + +L RDS ++ +S+ + +FL + G+LA G
Sbjct: 336 TNKDDDNIL-FRDSANATSLPVQDSSSVPLPTFL-VAGGSLAFG 377
>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
sapiens]
Length = 365
Score = 119 bits (299), Expect = 4e-27
Identities = 102/329 (31%), Positives = 143/329 (43%), Gaps = 26/329 (7%)
Query: 1 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVS 58
++ C+ L+ +L A AL A CP GV PG SV L CPGV D V
Sbjct: 2 LAVGCALLAALLAAPGAAL--APRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVH 59
Query: 59 WFRDGEPKLLQGPD--SGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARP 116
W +P P +G+G L+L D G Y C G GTV L + PP P
Sbjct: 60 WVLR-KPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEP 117
Query: 117 VVSC-QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCP---- 171
+SC + + N C W P L T+ + RK A+ + PC
Sbjct: 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQE-------PCQYSQE 170
Query: 172 QDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESVP 230
V G S Y +++ + +G+ ++ IL+PDPP + V +V
Sbjct: 171 SQKFSCQLAVPEGDS--SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVA 228
Query: 231 GYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLP 288
PR L +W P SW + L+F L+YR + ++T L+ VI DA +GL
Sbjct: 229 RNPRWLSVTWQDPHSWNSS-FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLR 287
Query: 289 HAVRVSARDFLDAGTWSTWSPEAWGTPST 317
H V++ A++ G WS WSPEA GTP T
Sbjct: 288 HVVQLRAQEEFGQGEWSEWSPEAMGTPWT 316
>gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens]
Length = 229
Score = 96.3 bits (238), Expect = 4e-20
Identities = 71/218 (32%), Positives = 106/218 (48%), Gaps = 24/218 (11%)
Query: 112 PPAR---PVVSCQAADYE-NFSCTWS--PSQISGLPTRYLTSYRKKTVLGADSQRRSPST 165
PPA P V C+A+ Y C+W+ P+ S P ++ +YR LG ++ S
Sbjct: 24 PPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYR----LGMAARGHS--- 76
Query: 166 GPWPCPQDPLGAARCVVHGAEFWSQ--YRINVTEVNPLGASTRLLDVSLQSILRPDPPQG 223
WPC Q + C + + +S Y +NVT V+P G+S+ + + I++PDPP+G
Sbjct: 77 --WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEG 134
Query: 224 LRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDA 283
+R+ P R+L+ W P SWP F LK+ ++Y+ + V P I A
Sbjct: 135 VRLS--PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRA 192
Query: 284 VAGLPHA---VRVSARDFLDAGTWSTWSPEAWGTPSTG 318
V P A V+V+A+D D G S WS A T S G
Sbjct: 193 VR--PRARYYVQVAAQDLTDYGELSDWSLPATATMSLG 228
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 70.5 bits (171), Expect = 2e-12
Identities = 62/239 (25%), Positives = 100/239 (41%), Gaps = 30/239 (12%)
Query: 93 ICQTLDGALGGTVTLQLGYPPARPV-VSCQAADYENFSCTWSPSQ--ISGLPTRYLTSYR 149
+C DG++ L +G PP +PV +SC + + ++ +C W+P + L T Y Y+
Sbjct: 115 VCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYK 174
Query: 150 KKTVLGADSQRRSPSTGPWPC--PQDPLGAARCVVHGAEFWSQYRINVTEVNPLG-ASTR 206
+ ++ + GP C P+D ++ Y I V N LG A +
Sbjct: 175 LRWYGQDNTCEEYHTVGPHSCHIPKD-----------LALFTPYEIWVEATNRLGSARSD 223
Query: 207 LLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLL--KFRLQYRPAQ 264
+L + + ++ DPP + V V G +L W P P FL K++++YR
Sbjct: 224 VLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSP---PALKDFLFQAKYQIRYRVED 280
Query: 265 HPAWSTVEPAGLEEV--ITDAVAGLPHAVRVSARDF-----LDAGTWSTWS-PEAWGTP 315
W V+ + + G + V+V F AG WS WS P A TP
Sbjct: 281 SVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTP 339
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 67.4 bits (163), Expect = 2e-11
Identities = 59/208 (28%), Positives = 87/208 (41%), Gaps = 24/208 (11%)
Query: 112 PPARP-VVSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPC 170
PP +P + C++ + E F+C W P GLPT Y +Y R T C
Sbjct: 27 PPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTY-----------HREGETLMHEC 75
Query: 171 PQDPLGAARCVVHGAEF---WSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRV 226
P G G ++ W Y + V N +G+S + L V + I++PDPP L V
Sbjct: 76 PDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAV 135
Query: 227 ESVPGYPRR--LRASWTYPASWPCQP-HFLLKFRLQYRPAQHPAWSTVEPAG--LEEVIT 281
E R+ L W+ P + F L + ++ +P + W + AG E I
Sbjct: 136 EVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE-IHFAGQQTEFKIL 194
Query: 282 DAVAGLPHAVRVSARDFLDAGTWSTWSP 309
G + V+V + D G WS WSP
Sbjct: 195 SLHPGQKYLVQVRCKP--DHGYWSAWSP 220
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 53.9 bits (128), Expect = 2e-07
Identities = 54/239 (22%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query: 105 VTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSP 163
+T+ G PP +P +SC + + C W + + L T + T AD + +
Sbjct: 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
Query: 164 STGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTR-LLDVSLQSILRPDPPQ 222
+ P C D + ++ + V N LG T ++ ++P+PP
Sbjct: 178 T--PTSCTVD---------YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
Query: 223 GLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE---- 278
L V + L+ +WT P+ + +LK+ +QYR WS + P
Sbjct: 227 NLSVINSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
Query: 279 -VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL---HTQ 333
+ D + R+ G WS WS EA G K W ++ HTQ
Sbjct: 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 53.1 bits (126), Expect = 4e-07
Identities = 49/216 (22%), Positives = 82/216 (37%), Gaps = 21/216 (9%)
Query: 105 VTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSP 163
+T+ G PP +P +SC + + C W + + L T + T AD + +
Sbjct: 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
Query: 164 STGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTR-LLDVSLQSILRPDPPQ 222
+ P C D + ++ + V N LG T ++ ++P+PP
Sbjct: 178 T--PTSCTVD---------YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
Query: 223 GLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE---- 278
L V + L+ +WT P+ + +LK+ +QYR WS + P
Sbjct: 227 NLSVINSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
Query: 279 -VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWG 313
+ D + R+ G WS WS EA G
Sbjct: 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
>gi|24497438 interleukin 12B precursor [Homo sapiens]
Length = 328
Score = 50.1 bits (118), Expect = 3e-06
Identities = 64/306 (20%), Positives = 107/306 (34%), Gaps = 61/306 (19%)
Query: 40 PGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGPDSGLGHELVLAQADSTDEGTYIC----- 94
PG V L C D ++W D ++L G G L + + D G Y C
Sbjct: 42 PGEMVVLTCD-TPEEDGITWTLDQSSEVL-----GSGKTLTIQVKEFGDAGQYTCHKGGE 95
Query: 95 ----------QTLDGALGGTVTLQLGYPPARPVVSCQAADYEN-FSCTWSPSQISGLPTR 143
+ DG + P + + C+A +Y F+C W
Sbjct: 96 VLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWW----------- 144
Query: 144 YLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGA 203
LT+ S R S C L A R V G +Y + E + A
Sbjct: 145 -LTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAER--VRGDNKEYEYSVECQEDSACPA 201
Query: 204 STRLLDVS-------------------LQSILRPDPPQGLRVESVPGYPRRLRASWTYPA 244
+ L + ++ I++PDPP+ L+++ + R++ SW YP
Sbjct: 202 AEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKN-SRQVEVSWEYPD 260
Query: 245 SWPCQPH--FLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAG 302
+W PH F L F +Q + + ++ + ++ V A+D +
Sbjct: 261 TW-STPHSYFSLTFCVQVQGKSKR--EKKDRVFTDKTSATVICRKNASISVRAQDRYYSS 317
Query: 303 TWSTWS 308
+WS W+
Sbjct: 318 SWSEWA 323
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 47.8 bits (112), Expect = 2e-05
Identities = 55/216 (25%), Positives = 84/216 (38%), Gaps = 32/216 (14%)
Query: 113 PARPV-VSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCP 171
PA+P +SC +N +CTWSP G T Y T Y K + + +T
Sbjct: 54 PAKPENISCVYYYRKNLTCTWSP----GKETSY-TQYTVKRTYAFGEKHDNCTTN--SST 106
Query: 172 QDPLGAARCVVHGAEFWSQYRINVTEVNPLGA-STRLLDVSLQSILRPDPPQGLRVESVP 230
+ + + Y I V N G + + L++I + +PP+ RV+ V
Sbjct: 107 SENRASCSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVL 166
Query: 231 GYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPA-------------GLE 277
G R ++ W P P LK+ L++R +W V A GL+
Sbjct: 167 GIKRMIQIEWIKPELAPVSSD--LKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQ 224
Query: 278 EVITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWG 313
T+ V L AV+ ++ WS WS E G
Sbjct: 225 P-FTEYVIALRCAVK-------ESKFWSDWSQEKMG 252
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 45.4 bits (106), Expect = 9e-05
Identities = 37/162 (22%), Positives = 65/162 (40%), Gaps = 10/162 (6%)
Query: 86 STDEGTYICQTLDGALGGTVTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRY 144
S GT + T + + GTV GYPP P ++C+ D + C+W+P +++ L
Sbjct: 307 SASSGTNVVFTTEDNIFGTVIFA-GYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGPR 365
Query: 145 LTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS 204
TSY R + P + ++ E Y + NPLG S
Sbjct: 366 ATSYTLVESFSGKYVRLKRAEAP---TNESYQLLFQMLPNQEI---YNFTLNAHNPLGRS 419
Query: 205 TRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASW 246
+ V++ + P P +V+ + ++ SW P ++
Sbjct: 420 QSTILVNITEKVYPHTPTSFKVKDINS--TAVKLSWHLPGNF 459
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 45.4 bits (106), Expect = 9e-05
Identities = 37/162 (22%), Positives = 65/162 (40%), Gaps = 10/162 (6%)
Query: 86 STDEGTYICQTLDGALGGTVTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRY 144
S GT + T + + GTV GYPP P ++C+ D + C+W+P +++ L
Sbjct: 307 SASSGTNVVFTTEDNIFGTVIFA-GYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGPR 365
Query: 145 LTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS 204
TSY R + P + ++ E Y + NPLG S
Sbjct: 366 ATSYTLVESFSGKYVRLKRAEAP---TNESYQLLFQMLPNQEI---YNFTLNAHNPLGRS 419
Query: 205 TRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASW 246
+ V++ + P P +V+ + ++ SW P ++
Sbjct: 420 QSTILVNITEKVYPHTPTSFKVKDINS--TAVKLSWHLPGNF 459
>gi|27437045 colony stimulating factor 3 receptor isoform d
precursor [Homo sapiens]
Length = 783
Score = 43.9 bits (102), Expect = 2e-04
Identities = 61/223 (27%), Positives = 95/223 (42%), Gaps = 32/223 (14%)
Query: 105 VTLQLGYPPARP-VVSC-QAADYENFSCTWSPSQISGLPTRY-LTSYRKKTVLGADSQRR 161
V L+ GYPPA P +SC + C W P + LPT + L S++ + + Q +
Sbjct: 115 VELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSR----GNCQTQ 170
Query: 162 SPSTGPWPC-PQDPLGAARCVVHGAE--FWSQYRINVTEVNPLGAS-TRLLDVSLQSILR 217
S C P+D G + C + + I V N LG S + L + +++
Sbjct: 171 GDSI--LDCVPKD--GQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVK 226
Query: 218 PDPPQGLRV-----ESVPGYPRRLRASWTYPASWPCQP--HFLLKFRLQYRPAQHPA-WS 269
+PP LR E+ P L+ W P QP H K L+++P + A W+
Sbjct: 227 LEPPM-LRTMDPSPEAAPPQAGCLQLCWE-----PWQPGLHINQKCELRHKPQRGEASWA 280
Query: 270 TVEPAGLEEVITDAVAGLP---HAVRVSARDFLDAGTWSTWSP 309
V P LE + + LP + +++ + G WS WSP
Sbjct: 281 LVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSP 323
>gi|24496783 colony stimulating factor 3 receptor isoform c
precursor [Homo sapiens]
Length = 863
Score = 43.9 bits (102), Expect = 2e-04
Identities = 61/223 (27%), Positives = 95/223 (42%), Gaps = 32/223 (14%)
Query: 105 VTLQLGYPPARP-VVSC-QAADYENFSCTWSPSQISGLPTRY-LTSYRKKTVLGADSQRR 161
V L+ GYPPA P +SC + C W P + LPT + L S++ + + Q +
Sbjct: 115 VELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSR----GNCQTQ 170
Query: 162 SPSTGPWPC-PQDPLGAARCVVHGAE--FWSQYRINVTEVNPLGAS-TRLLDVSLQSILR 217
S C P+D G + C + + I V N LG S + L + +++
Sbjct: 171 GDSI--LDCVPKD--GQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVK 226
Query: 218 PDPPQGLRV-----ESVPGYPRRLRASWTYPASWPCQP--HFLLKFRLQYRPAQHPA-WS 269
+PP LR E+ P L+ W P QP H K L+++P + A W+
Sbjct: 227 LEPPM-LRTMDPSPEAAPPQAGCLQLCWE-----PWQPGLHINQKCELRHKPQRGEASWA 280
Query: 270 TVEPAGLEEVITDAVAGLP---HAVRVSARDFLDAGTWSTWSP 309
V P LE + + LP + +++ + G WS WSP
Sbjct: 281 LVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSP 323
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 43.9 bits (102), Expect = 2e-04
Identities = 61/223 (27%), Positives = 95/223 (42%), Gaps = 32/223 (14%)
Query: 105 VTLQLGYPPARP-VVSC-QAADYENFSCTWSPSQISGLPTRY-LTSYRKKTVLGADSQRR 161
V L+ GYPPA P +SC + C W P + LPT + L S++ + + Q +
Sbjct: 115 VELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSR----GNCQTQ 170
Query: 162 SPSTGPWPC-PQDPLGAARCVVHGAE--FWSQYRINVTEVNPLGAS-TRLLDVSLQSILR 217
S C P+D G + C + + I V N LG S + L + +++
Sbjct: 171 GDSI--LDCVPKD--GQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVK 226
Query: 218 PDPPQGLRV-----ESVPGYPRRLRASWTYPASWPCQP--HFLLKFRLQYRPAQHPA-WS 269
+PP LR E+ P L+ W P QP H K L+++P + A W+
Sbjct: 227 LEPPM-LRTMDPSPEAAPPQAGCLQLCWE-----PWQPGLHINQKCELRHKPQRGEASWA 280
Query: 270 TVEPAGLEEVITDAVAGLP---HAVRVSARDFLDAGTWSTWSP 309
V P LE + + LP + +++ + G WS WSP
Sbjct: 281 LVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSP 323
>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
[Homo sapiens]
Length = 836
Score = 43.9 bits (102), Expect = 2e-04
Identities = 61/223 (27%), Positives = 95/223 (42%), Gaps = 32/223 (14%)
Query: 105 VTLQLGYPPARP-VVSC-QAADYENFSCTWSPSQISGLPTRY-LTSYRKKTVLGADSQRR 161
V L+ GYPPA P +SC + C W P + LPT + L S++ + + Q +
Sbjct: 115 VELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSR----GNCQTQ 170
Query: 162 SPSTGPWPC-PQDPLGAARCVVHGAE--FWSQYRINVTEVNPLGAS-TRLLDVSLQSILR 217
S C P+D G + C + + I V N LG S + L + +++
Sbjct: 171 GDSI--LDCVPKD--GQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVK 226
Query: 218 PDPPQGLRV-----ESVPGYPRRLRASWTYPASWPCQP--HFLLKFRLQYRPAQHPA-WS 269
+PP LR E+ P L+ W P QP H K L+++P + A W+
Sbjct: 227 LEPPM-LRTMDPSPEAAPPQAGCLQLCWE-----PWQPGLHINQKCELRHKPQRGEASWA 280
Query: 270 TVEPAGLEEVITDAVAGLP---HAVRVSARDFLDAGTWSTWSP 309
V P LE + + LP + +++ + G WS WSP
Sbjct: 281 LVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSP 323
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 43.9 bits (102), Expect = 2e-04
Identities = 45/166 (27%), Positives = 64/166 (38%), Gaps = 16/166 (9%)
Query: 165 TGPW-PCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTRLLD---VSLQSILR-PD 219
T W PC P+G R VVHG QY V VN +G S + + +Q+ L P
Sbjct: 653 TNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS 712
Query: 220 PPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEV 279
P G+ + + G+ L W P P +L + L R H W V + +
Sbjct: 713 HPYGITLLNCDGHSMTL--GWKVPKFSGGSP--ILGYYLDKREVHHKNWHEVNSSPSKPT 768
Query: 280 ITDA---VAGLPHAVRVSARDFLDAGTWSTWSP----EAWGTPSTG 318
I G + +++A + G S S EAW P G
Sbjct: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 43.5 bits (101), Expect = 3e-04
Identities = 45/216 (20%), Positives = 80/216 (37%), Gaps = 4/216 (1%)
Query: 118 VSCQAADY-ENFSCTWSPSQISGLPTRYLT-SYRKKTVLGADSQRRSPSTGPWPCPQDPL 175
+SC+ Y +C WS S I L L Y + ++ +D P + P C
Sbjct: 434 ISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSD 493
Query: 176 GAARCVVHGAEFWSQYRINVTEVNPLGA-STRLLDVSLQSILRPDPPQGLRVESVPGYPR 234
G C+ S Y + + + LG+ + V S+++P PP ++ E
Sbjct: 494 GFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGL 553
Query: 235 RLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVS 294
L+ SW P F +++ L + Q + + + +AV+V
Sbjct: 554 -LKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVR 612
Query: 295 ARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL 330
+ G WS WS A+ +P P + ++
Sbjct: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRI 648
Score = 38.5 bits (88), Expect = 0.010
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 207 LLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHP 266
L+ V ++++PDPP GL +E L+ SW+ P P + +K+
Sbjct: 226 LMSVQPINMVKPDPPLGLHMEITD--DGNLKISWSSPPLVPFPLQYQVKYSENSTTVIRE 283
Query: 267 AWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWS-PEAWGTPSTGTIPKEI 324
A V L ++ + G + V+V + G WS WS P + T P +I
Sbjct: 284 ADKIVSATSL--LVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKI 340
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 43.5 bits (101), Expect = 3e-04
Identities = 45/216 (20%), Positives = 80/216 (37%), Gaps = 4/216 (1%)
Query: 118 VSCQAADY-ENFSCTWSPSQISGLPTRYLT-SYRKKTVLGADSQRRSPSTGPWPCPQDPL 175
+SC+ Y +C WS S I L L Y + ++ +D P + P C
Sbjct: 434 ISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSD 493
Query: 176 GAARCVVHGAEFWSQYRINVTEVNPLGA-STRLLDVSLQSILRPDPPQGLRVESVPGYPR 234
G C+ S Y + + + LG+ + V S+++P PP ++ E
Sbjct: 494 GFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGL 553
Query: 235 RLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVS 294
L+ SW P F +++ L + Q + + + +AV+V
Sbjct: 554 -LKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVR 612
Query: 295 ARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL 330
+ G WS WS A+ +P P + ++
Sbjct: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRI 648
Score = 38.5 bits (88), Expect = 0.010
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 207 LLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHP 266
L+ V ++++PDPP GL +E L+ SW+ P P + +K+
Sbjct: 226 LMSVQPINMVKPDPPLGLHMEITD--DGNLKISWSSPPLVPFPLQYQVKYSENSTTVIRE 283
Query: 267 AWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWS-PEAWGTPSTGTIPKEI 324
A V L ++ + G + V+V + G WS WS P + T P +I
Sbjct: 284 ADKIVSATSL--LVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKI 340
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 43.5 bits (101), Expect = 3e-04
Identities = 45/216 (20%), Positives = 80/216 (37%), Gaps = 4/216 (1%)
Query: 118 VSCQAADY-ENFSCTWSPSQISGLPTRYLT-SYRKKTVLGADSQRRSPSTGPWPCPQDPL 175
+SC+ Y +C WS S I L L Y + ++ +D P + P C
Sbjct: 434 ISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSD 493
Query: 176 GAARCVVHGAEFWSQYRINVTEVNPLGA-STRLLDVSLQSILRPDPPQGLRVESVPGYPR 234
G C+ S Y + + + LG+ + V S+++P PP ++ E
Sbjct: 494 GFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGL 553
Query: 235 RLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVS 294
L+ SW P F +++ L + Q + + + +AV+V
Sbjct: 554 -LKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVR 612
Query: 295 ARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL 330
+ G WS WS A+ +P P + ++
Sbjct: 613 CKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRI 648
Score = 38.5 bits (88), Expect = 0.010
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 207 LLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHP 266
L+ V ++++PDPP GL +E L+ SW+ P P + +K+
Sbjct: 226 LMSVQPINMVKPDPPLGLHMEITD--DGNLKISWSSPPLVPFPLQYQVKYSENSTTVIRE 283
Query: 267 AWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWS-PEAWGTPSTGTIPKEI 324
A V L ++ + G + V+V + G WS WS P + T P +I
Sbjct: 284 ADKIVSATSL--LVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKI 340
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 10/123 (8%)
Query: 189 SQYRINVTEVNPLGASTRLLDV-SLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWP 247
S + VT VN LG+S+ L + I+RP PP +R++ R W
Sbjct: 194 SNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR------ 247
Query: 248 CQPHFLLKFRLQYRPAQHPAWSTVE--PAGLEEVITDAVAGLPHAVRVSARDFLDAGTWS 305
+L RL+YRP+ W+ V A + D + ++S++ L G+WS
Sbjct: 248 -DEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWS 306
Query: 306 TWS 308
WS
Sbjct: 307 DWS 309
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 42.7 bits (99), Expect = 6e-04
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Query: 35 VQYGQPGRSVKLCCPGVTAGDPVSWFRDG----EPKLLQGPDSGLGHELVLAQADSTDEG 90
+ +G PGR V+L C AG V W++DG LQ G L L A D G
Sbjct: 1091 LHFGAPGR-VELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAG 1149
Query: 91 TYICQTLDGALGGTVTLQLGYPPAR 115
Y+C+T A+ T + L PP +
Sbjct: 1150 EYVCETRHEAI--TFNVILAEPPVQ 1172
Score = 38.1 bits (87), Expect = 0.014
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Query: 40 PGRSVKLCCPGVTAGDPVSWFRDGEP----KLLQGPDSGLGHELVLAQADSTDEGTYICQ 95
PG V L C AG PV W +G P + L+ G L + A G Y CQ
Sbjct: 1187 PGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQ 1246
Query: 96 T--LDGALGGTVTLQLGYPPARPVVSCQAA 123
+ GA + T+Q+ PP R VV+ +AA
Sbjct: 1247 SGAAPGAPSLSFTVQVAEPPVR-VVAPEAA 1275
Score = 33.5 bits (75), Expect = 0.34
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 44 VKLCCPGVTAGDPVSWFRDG----EPKLLQGPDSGLGHELVLAQADSTDEGTYICQT 96
V L C P +W++DG E +LL G H L+L +A D G + C+T
Sbjct: 734 VVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRT 790
Score = 32.7 bits (73), Expect = 0.58
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 40 PGRSVKLCCPGVTAGDPVSWFRDGEPKLLQG----PDSGLGHELVLAQADSTDEGTYIC 94
PG ++L G PV W++DGE QG +G L + A S D G Y+C
Sbjct: 1283 PGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLC 1341
Score = 32.3 bits (72), Expect = 0.75
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 44 VKLCCPGVTAGDPVSWFRDG----EPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDG 99
V L C PV W++DG E + L G LVL A D G ++C D
Sbjct: 1007 VVLMCELSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDD 1066
Query: 100 ALGGTVTLQLGYPPARPV 117
+ TVT+ PP R V
Sbjct: 1067 SAFFTVTVTA--PPERIV 1082
Score = 31.6 bits (70), Expect = 1.3
Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 9/67 (13%)
Query: 41 GRSVKLCCPGVTAGDP---VSWFRDGEP----KLLQGPDSGLGHELVLAQADSTDEGTYI 93
G +L C V G+P V W + G+ + L P G H L+L A TD G Y+
Sbjct: 26 GAEAELKC--VVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYV 83
Query: 94 CQTLDGA 100
C+ + A
Sbjct: 84 CRARNAA 90
Score = 30.0 bits (66), Expect = 3.7
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 8/77 (10%)
Query: 44 VKLCCPGVTAGDPVSWFRDGEPKLLQGPDSGLGHE-----LVLAQADSTDEGTYICQTLD 98
V L C V W +DGE ++++ P L E LVL D G Y+C+ D
Sbjct: 916 VVLTCELCRPWAEVRWTKDGE-EVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDD 974
Query: 99 GALGGTVTLQLGYPPAR 115
+ TVT+ PP R
Sbjct: 975 ESASFTVTVT--EPPVR 989
Score = 28.9 bits (63), Expect = 8.3
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 6/69 (8%)
Query: 32 PPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGP-----DSGLGHELVLAQADS 86
PP + GR L +G V W R+G +L G G H LV+
Sbjct: 1814 PPREKTVLVGRRAVLEVTVSRSGGHVCWLREGA-ELCPGDKYEMRSHGPTHSLVIHDVRP 1872
Query: 87 TDEGTYICQ 95
D+GTY CQ
Sbjct: 1873 EDQGTYCCQ 1881
>gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens]
Length = 1007
Score = 42.7 bits (99), Expect = 6e-04
Identities = 20/45 (44%), Positives = 31/45 (68%), Gaps = 1/45 (2%)
Query: 57 VSWFRDGEPKLLQ-GPDSGLGHELVLAQADSTDEGTYICQTLDGA 100
VSW++DG+P LQ G + G L++A+A+ +DEGTY+C + A
Sbjct: 169 VSWWKDGKPLALQPGRHTVSGGSLLMARAEKSDEGTYMCVATNSA 213
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 9/169 (5%)
Query: 182 VHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSI--LRPDPPQGLRVESVPGYPRRLRAS 239
+ G + +++Y + N G D+++ ++ + PPQ + +E V R ++ S
Sbjct: 585 LEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNS--RSIKVS 642
Query: 240 WTYPASWPCQPHFLLKFRLQYRPA-QHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDF 298
W P S Q F+ +++++R + T+EP L + T G ++ +VSA
Sbjct: 643 WLPPPSGT-QNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTV 701
Query: 299 LDAGTWSTWSPEAWGTPSTGTIPKEIPAW-GQLHTQPEVEPQVDSPAPP 346
G S W TP ++P LH +P+ + S PP
Sbjct: 702 NGTGPPSNWYTAE--TPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPP 748
>gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo
sapiens]
Length = 264
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/137 (25%), Positives = 51/137 (37%), Gaps = 37/137 (27%)
Query: 19 LVSASSPCPQAWG------PPGVQYGQPGRSVKLCCPGVTAG---DPVSWFRD------- 62
L++ + C +W PP G PG+ V + C G ++ + V+W++
Sbjct: 33 LLTLLTHCAGSWAQSVLTQPPSAS-GTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPK 91
Query: 63 -----------GEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGAL---------G 102
G P G SG L ++ S DE Y C D +L G
Sbjct: 92 LLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGPTCWVFGG 151
Query: 103 GTVTLQLGYPPARPVVS 119
GT LG P A P V+
Sbjct: 152 GTKLTVLGQPKAAPSVT 168
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 41.2 bits (95), Expect = 0.002
Identities = 77/302 (25%), Positives = 119/302 (39%), Gaps = 50/302 (16%)
Query: 14 AVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGPDS 73
A A V P+ PP Q PG SV L C V A P + G +L + +
Sbjct: 219 APANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEM 278
Query: 74 GLGHELVLAQADSTDEGTYICQTLD--GALGGT--VTLQ-LGYPPARPVVSCQAADYENF 128
+G VL ++ Y C + G + T VT++ L PP VV+ A +
Sbjct: 279 PVGRN-VLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTA--TSV 335
Query: 129 SCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFW 188
+ TW S S T Y Y R + + GP+ D + R + G +
Sbjct: 336 TLTWD-SGNSEPVTYYGIQY-----------RAAGTEGPFQ-EVDGVATTRYSIGGLSPF 382
Query: 189 SQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRV---ESVPGYP-----RRLRASW 240
S+Y V VN +G R P + +R E P P R+ ++
Sbjct: 383 SEYAFRVLAVNSIG--------------RGPPSEAVRARTGEQAPSSPPRRVQARMLSAS 428
Query: 241 TYPASW--PCQPHFLLK-FRLQYRP-AQHP--AWSTVE-PAGLEEVITDAVAGLPHAVRV 293
T W P +P+ L++ +R+ Y P ++ P AW AGL + + G+ +++RV
Sbjct: 429 TMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRV 488
Query: 294 SA 295
A
Sbjct: 489 LA 490
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,207,823
Number of Sequences: 37866
Number of extensions: 1110069
Number of successful extensions: 4912
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 4473
Number of HSP's gapped (non-prelim): 564
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.