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Search of human proteins with 22202619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22202619 cathepsin L1 preproprotein [Homo sapiens] 704 0.0
gi|4503155 cathepsin L1 preproprotein [Homo sapiens] 704 0.0
gi|23110960 cathepsin L2 preproprotein [Homo sapiens] 552 e-157
gi|4503151 cathepsin K preproprotein [Homo sapiens] 333 2e-91
gi|23110962 cathepsin S preproprotein [Homo sapiens] 323 1e-88
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] 229 3e-60
gi|23110957 cathepsin H isoform b precursor [Homo sapiens] 225 4e-59
gi|6042196 cathepsin F [Homo sapiens] 184 1e-46
gi|4557501 cathepsin O preproprotein [Homo sapiens] 136 3e-32
gi|23110964 cathepsin W preproprotein [Homo sapiens] 127 1e-29
gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro... 126 2e-29
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] 117 1e-26
gi|22538437 cathepsin B preproprotein [Homo sapiens] 100 2e-21
gi|22538435 cathepsin B preproprotein [Homo sapiens] 100 2e-21
gi|22538433 cathepsin B preproprotein [Homo sapiens] 100 2e-21
gi|22538431 cathepsin B preproprotein [Homo sapiens] 100 2e-21
gi|4503139 cathepsin B preproprotein [Homo sapiens] 100 2e-21
gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens] 94 2e-19
gi|22538442 cathepsin Z preproprotein [Homo sapiens] 91 1e-18
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa... 81 1e-15
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 78 1e-14
gi|239754415 PREDICTED: hypothetical protein XP_002345991 [Homo ... 30 2.3
gi|239748949 PREDICTED: hypothetical protein XP_002346841 [Homo ... 30 2.3
gi|239742971 PREDICTED: hypothetical protein XP_002342727 [Homo ... 30 2.3
gi|215490104 calpain 11 [Homo sapiens] 30 3.0
gi|32307142 phosphatidylinositol transfer protein, cytoplasmic 1... 30 3.0
gi|32307140 phosphatidylinositol transfer protein, cytoplasmic 1... 30 3.0
gi|4557367 bleomycin hydrolase [Homo sapiens] 30 3.9
gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens] 29 5.1
gi|33413400 esterase D/formylglutathione hydrolase [Homo sapiens] 28 8.7
>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 704 bits (1816), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
Query: 61 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
Sbjct: 61 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240
Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
Sbjct: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300
Query: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Sbjct: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 704 bits (1816), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
Query: 61 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
Sbjct: 61 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240
Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
Sbjct: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300
Query: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Sbjct: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
Length = 334
Score = 552 bits (1423), Expect = e-157
Identities = 259/334 (77%), Positives = 291/334 (87%), Gaps = 1/334 (0%)
Query: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
MN +L+LAAFCLGIASA FD +L+ +W +WKA H RLYG NEEGWRRAVWEKNMKMIE
Sbjct: 1 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60
Query: 61 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
LHN EY +GKH FTMAMNAFGDMT+EEFRQ+M F+N+K RKGKVF+EPLF + P+SVDW
Sbjct: 61 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120
Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
R+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG
Sbjct: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180
Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGF-VDIPKQEKALMKAV 239
G M AFQYV++NGGLDSEESYPY A +E CKY P+ SVANDTGF V P +EKALMKAV
Sbjct: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240
Query: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299
ATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE S+N+KYWLVK
Sbjct: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300
Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
NSWG EWG GYVK+AKD+ NHCGIA+AASYP V
Sbjct: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>gi|4503151 cathepsin K preproprotein [Homo sapiens]
Length = 329
Score = 333 bits (853), Expect = 2e-91
Identities = 168/332 (50%), Positives = 218/332 (65%), Gaps = 15/332 (4%)
Query: 7 LAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQE 65
L L + S L + L+ W WK H + Y +E RR +WEKN+K I +HN E
Sbjct: 4 LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63
Query: 66 YREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFY-----EAPRSVDW 120
G H++ +AMN GDMTSEE Q M G + P + L+ AP SVD+
Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDY 121
Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC N+GC G
Sbjct: 122 RKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGG 179
Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAV 239
G M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ EKAL +AV
Sbjct: 180 GYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAV 239
Query: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299
A VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VGYG + NK+W++K
Sbjct: 240 ARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKHWIIK 295
Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331
NSWGE WG GY+ MA+++ N CGIA+ AS+P
Sbjct: 296 NSWGENWGNKGYILMARNKNNACGIANLASFP 327
>gi|23110962 cathepsin S preproprotein [Homo sapiens]
Length = 331
Score = 323 bits (828), Expect = 1e-88
Identities = 163/338 (48%), Positives = 220/338 (65%), Gaps = 19/338 (5%)
Query: 5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHN 63
L+ A A L D +L+ W WK + + Y NEE RR +WEKN+K + LHN
Sbjct: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63
Query: 64 QEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA------PRS 117
E+ G HS+ + MN GDMTSEE +M+ R +Q + Y++ P S
Sbjct: 64 LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL-----RVPSQWQRNITYKSNPNRILPDS 118
Query: 118 VDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNE 176
VDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178
Query: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKAL 235
GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVL 238
Query: 236 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKY 295
+AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + +Y
Sbjct: 239 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEY 293
Query: 296 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
WLVKNSWG +G GY++MA+++ NHCGIAS SYP +
Sbjct: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331
>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
Length = 335
Score = 229 bits (583), Expect = 3e-60
Identities = 130/339 (38%), Positives = 188/339 (55%), Gaps = 23/339 (6%)
Query: 3 PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59
P L A+ LG+ +A L + + + W + H + Y E R + N + I
Sbjct: 6 PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65
Query: 60 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRS 117
HN G H+F MA+N F DM+ E + + + QN K + Y P S
Sbjct: 66 NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119
Query: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176
VDWR+KG +V+PVKNQG CGSCW FS TGALE + TG+++SL+EQ LVDC+ N
Sbjct: 120 VDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179
Query: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKA 234
GC GGL AF+Y+ N G+ E++YPY+ + CK+ P ++ D + I E+A
Sbjct: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEA 238
Query: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDN 292
+++AVA P+S A + + F+ Y+ GIY C + + ++H VL VGYG E +
Sbjct: 239 MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293
Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331
YW+VKNSWG +WGM GY + + +N CG+A+ ASYP
Sbjct: 294 IPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 331
>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
Length = 323
Score = 225 bits (574), Expect = 4e-59
Identities = 125/325 (38%), Positives = 182/325 (56%), Gaps = 20/325 (6%)
Query: 14 IASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSF 73
+ +A L + + + W + H + Y E R + N + I HN G H+F
Sbjct: 8 LCAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTF 63
Query: 74 TMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKG-YVTPVK 130
MA+N F DM+ E + + + QN K + Y P SVDWR+KG +V+PVK
Sbjct: 64 KMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPSVDWRKKGNFVSPVK 121
Query: 131 NQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYV 190
NQG CGSCW FS TGALE + TG+++SL+EQ LVDC+ N GC GGL AF+Y+
Sbjct: 122 NQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYI 181
Query: 191 QDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKALMKAVATVGPISVA 248
N G+ E++YPY+ + CK+ P ++ D + I E+A+++AVA P+S A
Sbjct: 182 LYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEAMVEAVALYNPVSFA 240
Query: 249 IDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEW 306
+ + F+ Y+ GIY C + + ++H VL VGYG E + YW+VKNSWG +W
Sbjct: 241 FEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQW 295
Query: 307 GMGGYVKMAKDRRNHCGIASAASYP 331
GM GY + + +N CG+A+ ASYP
Sbjct: 296 GMNGYFLIERG-KNMCGLAACASYP 319
>gi|6042196 cathepsin F [Homo sapiens]
Length = 484
Score = 184 bits (467), Expect = 1e-46
Identities = 116/302 (38%), Positives = 163/302 (53%), Gaps = 16/302 (5%)
Query: 36 HNRLYGMNEEG-WRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNG 94
+NR Y EE WR +V+ NM + Q G + + F D+T EEFR +
Sbjct: 194 YNRTYESKEEARWRLSVFVNNMVRAQ-KIQALDRGTAQY--GVTKFSDLTEEEFRTIYLN 250
Query: 95 FQNRKPRKGKVFQEPLFYE-APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFR 153
RK K+ Q + AP DWR KG VT VK+QG CGSCWAFS TG +EGQ F
Sbjct: 251 TLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFL 310
Query: 154 KTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY 213
G L+SLSEQ L+DC + ++ C GGL A+ +++ GGL++E+ Y Y+ +SC +
Sbjct: 311 NQGTLLSLSEQELLDCD--KMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNF 368
Query: 214 NPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIY--FEPDCSS 271
+ + + V++ + E+ L +A GPISVAI+A FY+ GI P CS
Sbjct: 369 SAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSP 426
Query: 272 EDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331
+DH VL+VGYG S + +W +KNSWG +WG GY + + CG+ + AS
Sbjct: 427 WLIDHAVLLVGYGNRS----DVPFWAIKNSWGTDWGEKGYYYLHRG-SGACGVNTMASSA 481
Query: 332 TV 333
V
Sbjct: 482 VV 483
>gi|4557501 cathepsin O preproprotein [Homo sapiens]
Length = 321
Score = 136 bits (342), Expect = 3e-32
Identities = 90/263 (34%), Positives = 130/263 (49%), Gaps = 24/263 (9%)
Query: 77 MNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPR-----SVDWREKGYVTPVKN 131
+N F + EEF+ + + KP K + + P DWR+K VT V+N
Sbjct: 69 INQFSYLFPEEFKAI---YLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRN 125
Query: 132 QGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQ 191
Q CG CWAFS GA+E K L LS Q ++DCS N GCNGG A ++
Sbjct: 126 QQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNALNWLN 183
Query: 192 D-NGGLDSEESYPYEATEESCKY----NPKYSVANDTGFVDIPKQEKALMKAVATVGPIS 246
L + YP++A C Y + +S+ + + D QE + KA+ T GP+
Sbjct: 184 KMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAY-DFSDQEDEMAKALLTFGPLV 242
Query: 247 VAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEW 306
V +DA S+ Y GI + CSS + +H VL+ G+ ++ + YW+V+NSWG W
Sbjct: 243 VIVDA--VSWQDYLGGI-IQHHCSSGEANHAVLITGF----DKTGSTPYWIVRNSWGSSW 295
Query: 307 GMGGYVKMAKDRRNHCGIASAAS 329
G+ GY + K N CGIA + S
Sbjct: 296 GVDGYAHV-KMGSNVCGIADSVS 317
>gi|23110964 cathepsin W preproprotein [Homo sapiens]
Length = 376
Score = 127 bits (319), Expect = 1e-29
Identities = 97/326 (29%), Positives = 155/326 (47%), Gaps = 35/326 (10%)
Query: 25 LEAQWTKWKAMHNRLYGMNEEGWRRA-VWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 83
L+ + ++ NR Y EE R ++ N+ + QE G F + F D+
Sbjct: 38 LKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQ-RLQEEDLGTAEF--GVTPFSDL 94
Query: 84 TSEEFRQVMNGFQNRK---PRKGK-VFQEPLFYEAPRSVDWRE-KGYVTPVKNQGQCGSC 138
T EEF Q+ G++ P G+ + E P S DWR+ G ++P+K+Q C C
Sbjct: 95 TEEEFGQLY-GYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCC 153
Query: 139 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS 198
WA +A G +E + +S Q L+DC + +GC+GG + AF V +N GL S
Sbjct: 154 WAMAAAGNIETLWRISFWDFVDVSVQELLDCG--RCGDGCHGGFVWDAFITVLNNSGLAS 211
Query: 199 EESYPYEATEESCKYNPK--YSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESF 256
E+ YP++ + + +PK VA F+ + E + + +AT GPI+V I+ +
Sbjct: 212 EKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM--KPL 269
Query: 257 LFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTES----------------DNNKYWLV 298
Y++G+ C + +DH VL+VG+G +E YW++
Sbjct: 270 QLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWIL 329
Query: 299 KNSWGEEWGMGGYVKMAKDRRNHCGI 324
KNSWG +WG GY ++ + N CGI
Sbjct: 330 KNSWGAQWGEKGYFRLHRG-SNTCGI 354
>gi|239744067 PREDICTED: similar to Putative cathepsin L-like
protein 6 [Homo sapiens]
Length = 81
Score = 126 bits (317), Expect = 2e-29
Identities = 60/77 (77%), Positives = 64/77 (83%)
Query: 56 MKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAP 115
MKM E HNQEY +GKHSFTMAMN FGDMT+EEFRQVMNGFQ +K R GK FQE L E P
Sbjct: 1 MKMTEQHNQEYSQGKHSFTMAMNTFGDMTTEEFRQVMNGFQYQKHRNGKQFQERLLLEIP 60
Query: 116 RSVDWREKGYVTPVKNQ 132
SVDWREKGYVTPVK+Q
Sbjct: 61 TSVDWREKGYVTPVKDQ 77
>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
Length = 463
Score = 117 bits (293), Expect = 1e-26
Identities = 86/234 (36%), Positives = 121/234 (51%), Gaps = 31/234 (13%)
Query: 115 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM--FRKTGRLISLSEQNLVDC 169
P S DWR +V+PV+NQ CGSC++F++ G LE ++ + LS Q +V C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291
Query: 170 SGPQGNEGCNGGLMDY-AFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVA 220
S Q +GC GG A +Y QD G L E +PY T+ CK Y+ +Y
Sbjct: 292 S--QYAQGCEGGFPYLIAGKYAQDFG-LVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYV 348
Query: 221 NDTGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDM 274
GF +ALMK + GP++VA + ++ FL YK+GIY +P E
Sbjct: 349 G--GFYG--GCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELT 403
Query: 275 DHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA 328
+H VL+VGYG +S + YW+VKNSWG WG GY ++ + + C I S A
Sbjct: 404 NHAVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-TDECAIESIA 454
>gi|22538437 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 100 bits (249), Expect = 2e-21
Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)
Query: 99 KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
KP + +F E L + P S D RE+ P +++QG CGSCWAF A A+ ++
Sbjct: 67 KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124
Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
T +S +S ++L+ C G +GCNGG A+ + G + ES+ PY
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184
Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
E C Y+P Y G+ + EK +M +
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244
Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
GP+ A + FL YK G+Y + E M H + ++G+G E + YWLV
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297
Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
NSW +WG G+ K+ + ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323
>gi|22538435 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 100 bits (249), Expect = 2e-21
Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)
Query: 99 KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
KP + +F E L + P S D RE+ P +++QG CGSCWAF A A+ ++
Sbjct: 67 KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124
Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
T +S +S ++L+ C G +GCNGG A+ + G + ES+ PY
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184
Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
E C Y+P Y G+ + EK +M +
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244
Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
GP+ A + FL YK G+Y + E M H + ++G+G E + YWLV
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297
Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
NSW +WG G+ K+ + ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323
>gi|22538433 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 100 bits (249), Expect = 2e-21
Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)
Query: 99 KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
KP + +F E L + P S D RE+ P +++QG CGSCWAF A A+ ++
Sbjct: 67 KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124
Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
T +S +S ++L+ C G +GCNGG A+ + G + ES+ PY
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184
Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
E C Y+P Y G+ + EK +M +
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244
Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
GP+ A + FL YK G+Y + E M H + ++G+G E + YWLV
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297
Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
NSW +WG G+ K+ + ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323
>gi|22538431 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 100 bits (249), Expect = 2e-21
Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)
Query: 99 KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
KP + +F E L + P S D RE+ P +++QG CGSCWAF A A+ ++
Sbjct: 67 KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124
Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
T +S +S ++L+ C G +GCNGG A+ + G + ES+ PY
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184
Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
E C Y+P Y G+ + EK +M +
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244
Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
GP+ A + FL YK G+Y + E M H + ++G+G E + YWLV
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297
Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
NSW +WG G+ K+ + ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323
>gi|4503139 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 100 bits (249), Expect = 2e-21
Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)
Query: 99 KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
KP + +F E L + P S D RE+ P +++QG CGSCWAF A A+ ++
Sbjct: 67 KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124
Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
T +S +S ++L+ C G +GCNGG A+ + G + ES+ PY
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184
Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
E C Y+P Y G+ + EK +M +
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244
Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
GP+ A + FL YK G+Y + E M H + ++G+G E + YWLV
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297
Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
NSW +WG G+ K+ + ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323
>gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens]
Length = 51
Score = 94.0 bits (232), Expect = 2e-19
Identities = 43/51 (84%), Positives = 46/51 (90%)
Query: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAV 51
MNP+L+LAAF LGIASA LT DHSL+AQWTKWKA H RLYGMNEEGWRRAV
Sbjct: 1 MNPSLLLAAFFLGIASAALTRDHSLDAQWTKWKAKHKRLYGMNEEGWRRAV 51
>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
Length = 303
Score = 90.9 bits (224), Expect = 1e-18
Identities = 75/231 (32%), Positives = 114/231 (49%), Gaps = 45/231 (19%)
Query: 113 EAPRSVDWREK---GYVTPVKNQG---QCGSCWAFSATGALEGQM-FRKTGRLIS--LSE 163
+ P+S DWR Y + +NQ CGSCWA ++T A+ ++ ++ G S LS
Sbjct: 61 DLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 120
Query: 164 QNLVDCSGPQGNEG-CNGG----LMDYAFQYVQDNGGLDSEESYPYEATEESC-KYNP-- 215
QN++DC GN G C GG + DYA Q+ G+ E Y+A ++ C K+N
Sbjct: 121 QNVIDC----GNAGSCEGGNDLSVWDYAHQH-----GIPDETCNNYQAKDQECDKFNQCG 171
Query: 216 ------------KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGI 263
Y++ + + +EK + + A GPIS I A E Y GI
Sbjct: 172 TCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMAT-ERLANYTGGI 229
Query: 264 YFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314
Y E ++ ++H V V G+G SD +YW+V+NSWGE WG G++++
Sbjct: 230 YAEYQDTTY-INHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRI 275
>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
sapiens]
Length = 467
Score = 81.3 bits (199), Expect = 1e-15
Identities = 63/233 (27%), Positives = 96/233 (41%), Gaps = 41/233 (17%)
Query: 131 NQGQCGSCWAFSATGALEGQM-FRKTGRLIS-LSEQNLVDCSGPQGNEGCNGGLMDYAFQ 188
+QG C WAFS ++ G + LS QNL+ C Q +GC GG +D A+
Sbjct: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQ-QQGCRGGRLDGAWW 280
Query: 189 YVQDNGGLDSEESYPYEATE----------------------ESCKYNPKYSVANDTGFV 226
+++ G + S+ YP+ E ++ + P V N+ +
Sbjct: 281 FLRRRGVV-SDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQ 339
Query: 227 DIP-----KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFE-------PDCSSEDM 274
P +K +MK + GP+ ++ HE F YK GIY P+
Sbjct: 340 VTPVYRLGSNDKEIMKELMENGPVQALMEV-HEDFFLYKGGIYSHTPVSLGRPERYRRHG 398
Query: 275 DHGVLVVGYGFESTESDNN-KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 326
H V + G+G E+ KYW NSWG WG G+ ++ + N C I S
Sbjct: 399 THSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRG-VNECDIES 450
>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
Length = 476
Score = 78.2 bits (191), Expect = 1e-14
Identities = 68/251 (27%), Positives = 104/251 (41%), Gaps = 59/251 (23%)
Query: 109 PLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFS-ATGALEGQMFRKTGRLIS-LSEQNL 166
P F+ A S W G+ +Q C + WAFS A+ A + + GR + LS QNL
Sbjct: 218 PEFFVA--SYKW--PGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNL 273
Query: 167 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPY----EATEESC----------- 211
+ C + GCN G +D A+ Y++ G L S YP AT C
Sbjct: 274 ISCCA-KNRHGCNSGSIDRAWWYLRKRG-LVSHACYPLFKDQNATNNGCAMASRSDGRGK 331
Query: 212 ------------------KYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGH 253
+ +P Y V+++ E +MK + GP+ AI
Sbjct: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSN---------ETEIMKEIMQNGPVQ-AIMQVR 381
Query: 254 ESFLFYKEGIYFEPDCSSEDMD-------HGVLVVGYG-FESTESDNNKYWLVKNSWGEE 305
E F YK GIY ++++ + H V + G+G + K+W+ NSWG+
Sbjct: 382 EDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKS 441
Query: 306 WGMGGYVKMAK 316
WG GY ++ +
Sbjct: 442 WGENGYFRILR 452
>gi|239754415 PREDICTED: hypothetical protein XP_002345991 [Homo
sapiens]
Length = 205
Score = 30.4 bits (67), Expect = 2.3
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIPK 230
DS E YP E EESC P S+A + + P+
Sbjct: 119 DSPEGYPPETPEESCAARPSSSLARPSTYRSQPR 152
>gi|239748949 PREDICTED: hypothetical protein XP_002346841 [Homo
sapiens]
Length = 205
Score = 30.4 bits (67), Expect = 2.3
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIPK 230
DS E YP E EESC P S+A + + P+
Sbjct: 119 DSPEGYPPETPEESCAARPSSSLARPSTYRSQPR 152
>gi|239742971 PREDICTED: hypothetical protein XP_002342727 [Homo
sapiens]
Length = 205
Score = 30.4 bits (67), Expect = 2.3
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIPK 230
DS E YP E EESC P S+A + + P+
Sbjct: 119 DSPEGYPPETPEESCAARPSSSLARPSTYRSQPR 152
>gi|215490104 calpain 11 [Homo sapiens]
Length = 739
Score = 30.0 bits (66), Expect = 3.0
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 34/95 (35%)
Query: 80 FGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTP-VKN------- 131
FG+ + EE R RKG++F++PLF P S+ +++ G + V+N
Sbjct: 61 FGNQSFEELRAACL-------RKGELFEDPLFPAEPSSLGFKDLGPNSKNVQNISWQRPK 113
Query: 132 -------------------QGQCGSCWAFSATGAL 147
QG G CW +A G+L
Sbjct: 114 DIINNPLFIMDGISPTDICQGILGDCWLLAAIGSL 148
>gi|32307142 phosphatidylinositol transfer protein, cytoplasmic 1
isoform b [Homo sapiens]
Length = 268
Score = 30.0 bits (66), Expect = 3.0
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 202 YPYEATEESCKYNPKYSVANDTGFVD 227
YPY TE +C + PK+S+ +T + D
Sbjct: 90 YPYTITEYTCSFLPKFSIHIETKYED 115
>gi|32307140 phosphatidylinositol transfer protein, cytoplasmic 1
isoform a [Homo sapiens]
Length = 332
Score = 30.0 bits (66), Expect = 3.0
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 202 YPYEATEESCKYNPKYSVANDTGFVD 227
YPY TE +C + PK+S+ +T + D
Sbjct: 90 YPYTITEYTCSFLPKFSIHIETKYED 115
>gi|4557367 bleomycin hydrolase [Homo sapiens]
Length = 455
Score = 29.6 bits (65), Expect = 3.9
Identities = 11/22 (50%), Positives = 15/22 (68%)
Query: 296 WLVKNSWGEEWGMGGYVKMAKD 317
W V+NSWGE+ G GY+ M +
Sbjct: 392 WRVENSWGEDHGHKGYLCMTDE 413
>gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens]
Length = 2419
Score = 29.3 bits (64), Expect = 5.1
Identities = 17/50 (34%), Positives = 24/50 (48%)
Query: 78 NAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVT 127
N G +T +EFR + G P + EP F + +VD KGYV+
Sbjct: 2286 NLTGRLTHKEFRSCLRGLNYYLPMVEEDEHEPKFEKFLDAVDPGRKGYVS 2335
>gi|33413400 esterase D/formylglutathione hydrolase [Homo sapiens]
Length = 282
Score = 28.5 bits (62), Expect = 8.7
Identities = 23/90 (25%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 125 YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMD 184
Y+ P G+C + + S E K+G S SE LV + GCN D
Sbjct: 35 YLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGED 94
Query: 185 YAFQYVQDNGGLDSEESYPYEATEESCKYN 214
++ + G + +ATE+ K N
Sbjct: 95 ESWDFGTGAG-------FYVDATEDPWKTN 117
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,157,542
Number of Sequences: 37866
Number of extensions: 576512
Number of successful extensions: 1178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1086
Number of HSP's gapped (non-prelim): 33
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.