Guide to the Human Genome
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Search of human proteins with 22202619

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
         (333 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22202619 cathepsin L1 preproprotein [Homo sapiens]                 704   0.0  
gi|4503155 cathepsin L1 preproprotein [Homo sapiens]                  704   0.0  
gi|23110960 cathepsin L2 preproprotein [Homo sapiens]                 552   e-157
gi|4503151 cathepsin K preproprotein [Homo sapiens]                   333   2e-91
gi|23110962 cathepsin S preproprotein [Homo sapiens]                  323   1e-88
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]        229   3e-60
gi|23110957 cathepsin H isoform b precursor [Homo sapiens]            225   4e-59
gi|6042196 cathepsin F [Homo sapiens]                                 184   1e-46
gi|4557501 cathepsin O preproprotein [Homo sapiens]                   136   3e-32
gi|23110964 cathepsin W preproprotein [Homo sapiens]                  127   1e-29
gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro...   126   2e-29
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]       117   1e-26
gi|22538437 cathepsin B preproprotein [Homo sapiens]                  100   2e-21
gi|22538435 cathepsin B preproprotein [Homo sapiens]                  100   2e-21
gi|22538433 cathepsin B preproprotein [Homo sapiens]                  100   2e-21
gi|22538431 cathepsin B preproprotein [Homo sapiens]                  100   2e-21
gi|4503139 cathepsin B preproprotein [Homo sapiens]                   100   2e-21
gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens]         94   2e-19
gi|22538442 cathepsin Z preproprotein [Homo sapiens]                   91   1e-18
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa...    81   1e-15
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]       78   1e-14
gi|239754415 PREDICTED: hypothetical protein XP_002345991 [Homo ...    30   2.3  
gi|239748949 PREDICTED: hypothetical protein XP_002346841 [Homo ...    30   2.3  
gi|239742971 PREDICTED: hypothetical protein XP_002342727 [Homo ...    30   2.3  
gi|215490104 calpain 11 [Homo sapiens]                                 30   3.0  
gi|32307142 phosphatidylinositol transfer protein, cytoplasmic 1...    30   3.0  
gi|32307140 phosphatidylinositol transfer protein, cytoplasmic 1...    30   3.0  
gi|4557367 bleomycin hydrolase [Homo sapiens]                          30   3.9  
gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens]            29   5.1  
gi|33413400 esterase D/formylglutathione hydrolase [Homo sapiens]      28   8.7  

>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  704 bits (1816), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 1   MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
           MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1   MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 61  LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
           LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
Sbjct: 61  LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120

Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
           REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180

Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240
           GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240

Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300
           TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
Sbjct: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300

Query: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
           SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Sbjct: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333


>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  704 bits (1816), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 1   MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
           MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1   MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 61  LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
           LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
Sbjct: 61  LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120

Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
           REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180

Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240
           GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 240

Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300
           TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
Sbjct: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300

Query: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
           SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Sbjct: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333


>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
          Length = 334

 Score =  552 bits (1423), Expect = e-157
 Identities = 259/334 (77%), Positives = 291/334 (87%), Gaps = 1/334 (0%)

Query: 1   MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60
           MN +L+LAAFCLGIASA   FD +L+ +W +WKA H RLYG NEEGWRRAVWEKNMKMIE
Sbjct: 1   MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60

Query: 61  LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120
           LHN EY +GKH FTMAMNAFGDMT+EEFRQ+M  F+N+K RKGKVF+EPLF + P+SVDW
Sbjct: 61  LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120

Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
           R+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG
Sbjct: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180

Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGF-VDIPKQEKALMKAV 239
           G M  AFQYV++NGGLDSEESYPY A +E CKY P+ SVANDTGF V  P +EKALMKAV
Sbjct: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240

Query: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299
           ATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE   S+N+KYWLVK
Sbjct: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300

Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
           NSWG EWG  GYVK+AKD+ NHCGIA+AASYP V
Sbjct: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334


>gi|4503151 cathepsin K preproprotein [Homo sapiens]
          Length = 329

 Score =  333 bits (853), Expect = 2e-91
 Identities = 168/332 (50%), Positives = 218/332 (65%), Gaps = 15/332 (4%)

Query: 7   LAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQE 65
           L    L + S  L  +  L+  W  WK  H + Y    +E  RR +WEKN+K I +HN E
Sbjct: 4   LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63

Query: 66  YREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFY-----EAPRSVDW 120
              G H++ +AMN  GDMTSEE  Q M G   + P       + L+       AP SVD+
Sbjct: 64  ASLGVHTYELAMNHLGDMTSEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDY 121

Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180
           R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC     N+GC G
Sbjct: 122 RKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGG 179

Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAV 239
           G M  AFQYVQ N G+DSE++YPY   EESC YNP    A   G+ +IP+  EKAL +AV
Sbjct: 180 GYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAV 239

Query: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299
           A VGP+SVAIDA   SF FY +G+Y++  C+S++++H VL VGYG +      NK+W++K
Sbjct: 240 ARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKHWIIK 295

Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331
           NSWGE WG  GY+ MA+++ N CGIA+ AS+P
Sbjct: 296 NSWGENWGNKGYILMARNKNNACGIANLASFP 327


>gi|23110962 cathepsin S preproprotein [Homo sapiens]
          Length = 331

 Score =  323 bits (828), Expect = 1e-88
 Identities = 163/338 (48%), Positives = 220/338 (65%), Gaps = 19/338 (5%)

Query: 5   LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHN 63
           L+        A A L  D +L+  W  WK  + + Y   NEE  RR +WEKN+K + LHN
Sbjct: 4   LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63

Query: 64  QEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA------PRS 117
            E+  G HS+ + MN  GDMTSEE   +M+       R    +Q  + Y++      P S
Sbjct: 64  LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL-----RVPSQWQRNITYKSNPNRILPDS 118

Query: 118 VDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNE 176
           VDWREKG VT VK QG CG+CWAFSA GALE Q+  KTG+L+SLS QNLVDCS  + GN+
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178

Query: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKAL 235
           GCNGG M  AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY  A  + + ++P  +E  L
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVL 238

Query: 236 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKY 295
            +AVA  GP+SV +DA H SF  Y+ G+Y+EP C +++++HGVLVVGYG    + +  +Y
Sbjct: 239 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEY 293

Query: 296 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
           WLVKNSWG  +G  GY++MA+++ NHCGIAS  SYP +
Sbjct: 294 WLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331


>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
          Length = 335

 Score =  229 bits (583), Expect = 3e-60
 Identities = 130/339 (38%), Positives = 188/339 (55%), Gaps = 23/339 (6%)

Query: 3   PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59
           P L   A+ LG+    +A L  +   +  +  W + H + Y   E   R   +  N + I
Sbjct: 6   PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65

Query: 60  ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRS 117
             HN     G H+F MA+N F DM+  E +   + +  QN    K    +    Y  P S
Sbjct: 66  NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119

Query: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176
           VDWR+KG +V+PVKNQG CGSCW FS TGALE  +   TG+++SL+EQ LVDC+    N 
Sbjct: 120 VDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179

Query: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKA 234
           GC GGL   AF+Y+  N G+  E++YPY+  +  CK+ P  ++    D   + I   E+A
Sbjct: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEA 238

Query: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDN 292
           +++AVA   P+S A +   + F+ Y+ GIY    C  + + ++H VL VGYG    E + 
Sbjct: 239 MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293

Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331
             YW+VKNSWG +WGM GY  + +  +N CG+A+ ASYP
Sbjct: 294 IPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 331


>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
          Length = 323

 Score =  225 bits (574), Expect = 4e-59
 Identities = 125/325 (38%), Positives = 182/325 (56%), Gaps = 20/325 (6%)

Query: 14  IASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSF 73
           + +A L  +   +  +  W + H + Y   E   R   +  N + I  HN     G H+F
Sbjct: 8   LCAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTF 63

Query: 74  TMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKG-YVTPVK 130
            MA+N F DM+  E +   + +  QN    K    +    Y  P SVDWR+KG +V+PVK
Sbjct: 64  KMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPSVDWRKKGNFVSPVK 121

Query: 131 NQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYV 190
           NQG CGSCW FS TGALE  +   TG+++SL+EQ LVDC+    N GC GGL   AF+Y+
Sbjct: 122 NQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYI 181

Query: 191 QDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKALMKAVATVGPISVA 248
             N G+  E++YPY+  +  CK+ P  ++    D   + I   E+A+++AVA   P+S A
Sbjct: 182 LYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEAMVEAVALYNPVSFA 240

Query: 249 IDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEW 306
            +   + F+ Y+ GIY    C  + + ++H VL VGYG    E +   YW+VKNSWG +W
Sbjct: 241 FEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQW 295

Query: 307 GMGGYVKMAKDRRNHCGIASAASYP 331
           GM GY  + +  +N CG+A+ ASYP
Sbjct: 296 GMNGYFLIERG-KNMCGLAACASYP 319


>gi|6042196 cathepsin F [Homo sapiens]
          Length = 484

 Score =  184 bits (467), Expect = 1e-46
 Identities = 116/302 (38%), Positives = 163/302 (53%), Gaps = 16/302 (5%)

Query: 36  HNRLYGMNEEG-WRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNG 94
           +NR Y   EE  WR +V+  NM   +   Q    G   +   +  F D+T EEFR +   
Sbjct: 194 YNRTYESKEEARWRLSVFVNNMVRAQ-KIQALDRGTAQY--GVTKFSDLTEEEFRTIYLN 250

Query: 95  FQNRKPRKGKVFQEPLFYE-APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFR 153
              RK    K+ Q     + AP   DWR KG VT VK+QG CGSCWAFS TG +EGQ F 
Sbjct: 251 TLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFL 310

Query: 154 KTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY 213
             G L+SLSEQ L+DC   + ++ C GGL   A+  +++ GGL++E+ Y Y+   +SC +
Sbjct: 311 NQGTLLSLSEQELLDCD--KMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNF 368

Query: 214 NPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIY--FEPDCSS 271
           + + +       V++ + E+ L   +A  GPISVAI+A      FY+ GI     P CS 
Sbjct: 369 SAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSP 426

Query: 272 EDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331
             +DH VL+VGYG  S    +  +W +KNSWG +WG  GY  + +     CG+ + AS  
Sbjct: 427 WLIDHAVLLVGYGNRS----DVPFWAIKNSWGTDWGEKGYYYLHRG-SGACGVNTMASSA 481

Query: 332 TV 333
            V
Sbjct: 482 VV 483


>gi|4557501 cathepsin O preproprotein [Homo sapiens]
          Length = 321

 Score =  136 bits (342), Expect = 3e-32
 Identities = 90/263 (34%), Positives = 130/263 (49%), Gaps = 24/263 (9%)

Query: 77  MNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPR-----SVDWREKGYVTPVKN 131
           +N F  +  EEF+ +   +   KP K   +   +    P        DWR+K  VT V+N
Sbjct: 69  INQFSYLFPEEFKAI---YLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRN 125

Query: 132 QGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQ 191
           Q  CG CWAFS  GA+E     K   L  LS Q ++DCS    N GCNGG    A  ++ 
Sbjct: 126 QQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNALNWLN 183

Query: 192 D-NGGLDSEESYPYEATEESCKY----NPKYSVANDTGFVDIPKQEKALMKAVATVGPIS 246
                L  +  YP++A    C Y    +  +S+   + + D   QE  + KA+ T GP+ 
Sbjct: 184 KMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAY-DFSDQEDEMAKALLTFGPLV 242

Query: 247 VAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEW 306
           V +DA   S+  Y  GI  +  CSS + +H VL+ G+     ++ +  YW+V+NSWG  W
Sbjct: 243 VIVDA--VSWQDYLGGI-IQHHCSSGEANHAVLITGF----DKTGSTPYWIVRNSWGSSW 295

Query: 307 GMGGYVKMAKDRRNHCGIASAAS 329
           G+ GY  + K   N CGIA + S
Sbjct: 296 GVDGYAHV-KMGSNVCGIADSVS 317


>gi|23110964 cathepsin W preproprotein [Homo sapiens]
          Length = 376

 Score =  127 bits (319), Expect = 1e-29
 Identities = 97/326 (29%), Positives = 155/326 (47%), Gaps = 35/326 (10%)

Query: 25  LEAQWTKWKAMHNRLYGMNEEGWRRA-VWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 83
           L+  +  ++   NR Y   EE   R  ++  N+   +   QE   G   F   +  F D+
Sbjct: 38  LKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQ-RLQEEDLGTAEF--GVTPFSDL 94

Query: 84  TSEEFRQVMNGFQNRK---PRKGK-VFQEPLFYEAPRSVDWRE-KGYVTPVKNQGQCGSC 138
           T EEF Q+  G++      P  G+ +  E      P S DWR+  G ++P+K+Q  C  C
Sbjct: 95  TEEEFGQLY-GYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCC 153

Query: 139 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS 198
           WA +A G +E          + +S Q L+DC   +  +GC+GG +  AF  V +N GL S
Sbjct: 154 WAMAAAGNIETLWRISFWDFVDVSVQELLDCG--RCGDGCHGGFVWDAFITVLNNSGLAS 211

Query: 199 EESYPYEATEESCKYNPK--YSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESF 256
           E+ YP++    + + +PK    VA    F+ +   E  + + +AT GPI+V I+   +  
Sbjct: 212 EKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINM--KPL 269

Query: 257 LFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTES----------------DNNKYWLV 298
             Y++G+       C  + +DH VL+VG+G   +E                     YW++
Sbjct: 270 QLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWIL 329

Query: 299 KNSWGEEWGMGGYVKMAKDRRNHCGI 324
           KNSWG +WG  GY ++ +   N CGI
Sbjct: 330 KNSWGAQWGEKGYFRLHRG-SNTCGI 354


>gi|239744067 PREDICTED: similar to Putative cathepsin L-like
           protein 6 [Homo sapiens]
          Length = 81

 Score =  126 bits (317), Expect = 2e-29
 Identities = 60/77 (77%), Positives = 64/77 (83%)

Query: 56  MKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAP 115
           MKM E HNQEY +GKHSFTMAMN FGDMT+EEFRQVMNGFQ +K R GK FQE L  E P
Sbjct: 1   MKMTEQHNQEYSQGKHSFTMAMNTFGDMTTEEFRQVMNGFQYQKHRNGKQFQERLLLEIP 60

Query: 116 RSVDWREKGYVTPVKNQ 132
            SVDWREKGYVTPVK+Q
Sbjct: 61  TSVDWREKGYVTPVKDQ 77


>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
          Length = 463

 Score =  117 bits (293), Expect = 1e-26
 Identities = 86/234 (36%), Positives = 121/234 (51%), Gaps = 31/234 (13%)

Query: 115 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM--FRKTGRLISLSEQNLVDC 169
           P S DWR      +V+PV+NQ  CGSC++F++ G LE ++       +   LS Q +V C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291

Query: 170 SGPQGNEGCNGGLMDY-AFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVA 220
           S  Q  +GC GG     A +Y QD G L  E  +PY  T+  CK        Y+ +Y   
Sbjct: 292 S--QYAQGCEGGFPYLIAGKYAQDFG-LVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYV 348

Query: 221 NDTGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDM 274
              GF       +ALMK  +   GP++VA +  ++ FL YK+GIY      +P    E  
Sbjct: 349 G--GFYG--GCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELT 403

Query: 275 DHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA 328
           +H VL+VGYG +S    +  YW+VKNSWG  WG  GY ++ +   + C I S A
Sbjct: 404 NHAVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-TDECAIESIA 454


>gi|22538437 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  100 bits (249), Expect = 2e-21
 Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)

Query: 99  KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
           KP +  +F E L  + P S D RE+    P    +++QG CGSCWAF A  A+  ++   
Sbjct: 67  KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124

Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
           T   +S  +S ++L+ C G    +GCNGG    A+ +    G +     ES+    PY  
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184

Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
                           E     C       Y+P Y      G+    +   EK +M  + 
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244

Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
             GP+  A    +  FL YK G+Y     + E M  H + ++G+G E    +   YWLV 
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297

Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
           NSW  +WG  G+ K+ +  ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323


>gi|22538435 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  100 bits (249), Expect = 2e-21
 Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)

Query: 99  KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
           KP +  +F E L  + P S D RE+    P    +++QG CGSCWAF A  A+  ++   
Sbjct: 67  KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124

Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
           T   +S  +S ++L+ C G    +GCNGG    A+ +    G +     ES+    PY  
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184

Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
                           E     C       Y+P Y      G+    +   EK +M  + 
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244

Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
             GP+  A    +  FL YK G+Y     + E M  H + ++G+G E    +   YWLV 
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297

Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
           NSW  +WG  G+ K+ +  ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323


>gi|22538433 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  100 bits (249), Expect = 2e-21
 Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)

Query: 99  KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
           KP +  +F E L  + P S D RE+    P    +++QG CGSCWAF A  A+  ++   
Sbjct: 67  KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124

Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
           T   +S  +S ++L+ C G    +GCNGG    A+ +    G +     ES+    PY  
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184

Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
                           E     C       Y+P Y      G+    +   EK +M  + 
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244

Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
             GP+  A    +  FL YK G+Y     + E M  H + ++G+G E    +   YWLV 
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297

Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
           NSW  +WG  G+ K+ +  ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323


>gi|22538431 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  100 bits (249), Expect = 2e-21
 Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)

Query: 99  KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
           KP +  +F E L  + P S D RE+    P    +++QG CGSCWAF A  A+  ++   
Sbjct: 67  KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124

Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
           T   +S  +S ++L+ C G    +GCNGG    A+ +    G +     ES+    PY  
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184

Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
                           E     C       Y+P Y      G+    +   EK +M  + 
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244

Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
             GP+  A    +  FL YK G+Y     + E M  H + ++G+G E    +   YWLV 
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297

Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
           NSW  +WG  G+ K+ +  ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323


>gi|4503139 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  100 bits (249), Expect = 2e-21
 Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%)

Query: 99  KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154
           KP +  +F E L  + P S D RE+    P    +++QG CGSCWAF A  A+  ++   
Sbjct: 67  KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124

Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 204
           T   +S  +S ++L+ C G    +GCNGG    A+ +    G +     ES+    PY  
Sbjct: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184

Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240
                           E     C       Y+P Y      G+    +   EK +M  + 
Sbjct: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244

Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299
             GP+  A    +  FL YK G+Y     + E M  H + ++G+G E    +   YWLV 
Sbjct: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297

Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326
           NSW  +WG  G+ K+ +  ++HCGI S
Sbjct: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323


>gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens]
          Length = 51

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 43/51 (84%), Positives = 46/51 (90%)

Query: 1  MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAV 51
          MNP+L+LAAF LGIASA LT DHSL+AQWTKWKA H RLYGMNEEGWRRAV
Sbjct: 1  MNPSLLLAAFFLGIASAALTRDHSLDAQWTKWKAKHKRLYGMNEEGWRRAV 51


>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
          Length = 303

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 75/231 (32%), Positives = 114/231 (49%), Gaps = 45/231 (19%)

Query: 113 EAPRSVDWREK---GYVTPVKNQG---QCGSCWAFSATGALEGQM-FRKTGRLIS--LSE 163
           + P+S DWR      Y +  +NQ     CGSCWA ++T A+  ++  ++ G   S  LS 
Sbjct: 61  DLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 120

Query: 164 QNLVDCSGPQGNEG-CNGG----LMDYAFQYVQDNGGLDSEESYPYEATEESC-KYNP-- 215
           QN++DC    GN G C GG    + DYA Q+     G+  E    Y+A ++ C K+N   
Sbjct: 121 QNVIDC----GNAGSCEGGNDLSVWDYAHQH-----GIPDETCNNYQAKDQECDKFNQCG 171

Query: 216 ------------KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGI 263
                        Y++     +  +  +EK + +  A  GPIS  I A  E    Y  GI
Sbjct: 172 TCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMAT-ERLANYTGGI 229

Query: 264 YFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314
           Y E   ++  ++H V V G+G     SD  +YW+V+NSWGE WG  G++++
Sbjct: 230 YAEYQDTTY-INHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRI 275


>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
           sapiens]
          Length = 467

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 63/233 (27%), Positives = 96/233 (41%), Gaps = 41/233 (17%)

Query: 131 NQGQCGSCWAFSATGALEGQM-FRKTGRLIS-LSEQNLVDCSGPQGNEGCNGGLMDYAFQ 188
           +QG C   WAFS       ++     G +   LS QNL+ C   Q  +GC GG +D A+ 
Sbjct: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQ-QQGCRGGRLDGAWW 280

Query: 189 YVQDNGGLDSEESYPYEATE----------------------ESCKYNPKYSVANDTGFV 226
           +++  G + S+  YP+   E                      ++  + P   V N+  + 
Sbjct: 281 FLRRRGVV-SDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQ 339

Query: 227 DIP-----KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFE-------PDCSSEDM 274
             P       +K +MK +   GP+   ++  HE F  YK GIY         P+      
Sbjct: 340 VTPVYRLGSNDKEIMKELMENGPVQALMEV-HEDFFLYKGGIYSHTPVSLGRPERYRRHG 398

Query: 275 DHGVLVVGYGFESTESDNN-KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 326
            H V + G+G E+       KYW   NSWG  WG  G+ ++ +   N C I S
Sbjct: 399 THSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRG-VNECDIES 450


>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
          Length = 476

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 68/251 (27%), Positives = 104/251 (41%), Gaps = 59/251 (23%)

Query: 109 PLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFS-ATGALEGQMFRKTGRLIS-LSEQNL 166
           P F+ A  S  W   G+     +Q  C + WAFS A+ A +    +  GR  + LS QNL
Sbjct: 218 PEFFVA--SYKW--PGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNL 273

Query: 167 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPY----EATEESC----------- 211
           + C   +   GCN G +D A+ Y++  G L S   YP      AT   C           
Sbjct: 274 ISCCA-KNRHGCNSGSIDRAWWYLRKRG-LVSHACYPLFKDQNATNNGCAMASRSDGRGK 331

Query: 212 ------------------KYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGH 253
                             + +P Y V+++         E  +MK +   GP+  AI    
Sbjct: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSN---------ETEIMKEIMQNGPVQ-AIMQVR 381

Query: 254 ESFLFYKEGIYFEPDCSSEDMD-------HGVLVVGYG-FESTESDNNKYWLVKNSWGEE 305
           E F  YK GIY     ++++ +       H V + G+G     +    K+W+  NSWG+ 
Sbjct: 382 EDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKS 441

Query: 306 WGMGGYVKMAK 316
           WG  GY ++ +
Sbjct: 442 WGENGYFRILR 452


>gi|239754415 PREDICTED: hypothetical protein XP_002345991 [Homo
           sapiens]
          Length = 205

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIPK 230
           DS E YP E  EESC   P  S+A  + +   P+
Sbjct: 119 DSPEGYPPETPEESCAARPSSSLARPSTYRSQPR 152


>gi|239748949 PREDICTED: hypothetical protein XP_002346841 [Homo
           sapiens]
          Length = 205

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIPK 230
           DS E YP E  EESC   P  S+A  + +   P+
Sbjct: 119 DSPEGYPPETPEESCAARPSSSLARPSTYRSQPR 152


>gi|239742971 PREDICTED: hypothetical protein XP_002342727 [Homo
           sapiens]
          Length = 205

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIPK 230
           DS E YP E  EESC   P  S+A  + +   P+
Sbjct: 119 DSPEGYPPETPEESCAARPSSSLARPSTYRSQPR 152


>gi|215490104 calpain 11 [Homo sapiens]
          Length = 739

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 34/95 (35%)

Query: 80  FGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTP-VKN------- 131
           FG+ + EE R           RKG++F++PLF   P S+ +++ G  +  V+N       
Sbjct: 61  FGNQSFEELRAACL-------RKGELFEDPLFPAEPSSLGFKDLGPNSKNVQNISWQRPK 113

Query: 132 -------------------QGQCGSCWAFSATGAL 147
                              QG  G CW  +A G+L
Sbjct: 114 DIINNPLFIMDGISPTDICQGILGDCWLLAAIGSL 148


>gi|32307142 phosphatidylinositol transfer protein, cytoplasmic 1
           isoform b [Homo sapiens]
          Length = 268

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 11/26 (42%), Positives = 17/26 (65%)

Query: 202 YPYEATEESCKYNPKYSVANDTGFVD 227
           YPY  TE +C + PK+S+  +T + D
Sbjct: 90  YPYTITEYTCSFLPKFSIHIETKYED 115


>gi|32307140 phosphatidylinositol transfer protein, cytoplasmic 1
           isoform a [Homo sapiens]
          Length = 332

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 11/26 (42%), Positives = 17/26 (65%)

Query: 202 YPYEATEESCKYNPKYSVANDTGFVD 227
           YPY  TE +C + PK+S+  +T + D
Sbjct: 90  YPYTITEYTCSFLPKFSIHIETKYED 115


>gi|4557367 bleomycin hydrolase [Homo sapiens]
          Length = 455

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 11/22 (50%), Positives = 15/22 (68%)

Query: 296 WLVKNSWGEEWGMGGYVKMAKD 317
           W V+NSWGE+ G  GY+ M  +
Sbjct: 392 WRVENSWGEDHGHKGYLCMTDE 413


>gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens]
          Length = 2419

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 78   NAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVT 127
            N  G +T +EFR  + G     P   +   EP F +   +VD   KGYV+
Sbjct: 2286 NLTGRLTHKEFRSCLRGLNYYLPMVEEDEHEPKFEKFLDAVDPGRKGYVS 2335


>gi|33413400 esterase D/formylglutathione hydrolase [Homo sapiens]
          Length = 282

 Score = 28.5 bits (62), Expect = 8.7
 Identities = 23/90 (25%), Positives = 35/90 (38%), Gaps = 7/90 (7%)

Query: 125 YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMD 184
           Y+ P    G+C + +  S     E     K+G   S SE  LV  +      GCN    D
Sbjct: 35  YLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGED 94

Query: 185 YAFQYVQDNGGLDSEESYPYEATEESCKYN 214
            ++ +    G       +  +ATE+  K N
Sbjct: 95  ESWDFGTGAG-------FYVDATEDPWKTN 117


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,157,542
Number of Sequences: 37866
Number of extensions: 576512
Number of successful extensions: 1178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1086
Number of HSP's gapped (non-prelim): 33
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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