Guide to the Human Genome
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Search of human proteins with 221136939

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221136939 pre-mRNA processing factor 31 homolog [Homo
sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens]     967   0.0  
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]             129   5e-30
gi|32483374 nucleolar protein 5A [Homo sapiens]                       122   6e-28
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]    39   0.011
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]    39   0.011
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    37   0.042
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    37   0.042
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   36   0.071
gi|109134336 SH3-domain binding protein 5 (BTK-associated) isofo...    36   0.071
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    36   0.093
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is...    36   0.093
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]                   35   0.16 
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi...    35   0.16 
gi|17975763 myelin transcription factor 1 [Homo sapiens]               35   0.21 
gi|68348702 breast cancer metastasis suppressor 1 isoform 2 [Hom...    34   0.27 
gi|17530785 breast cancer metastasis suppressor 1 isoform 1 [Hom...    34   0.27 
gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens]           34   0.27 
gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens]           34   0.27 
gi|239743692 PREDICTED: hypothetical protein LOC402360 [Homo sap...    34   0.27 
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       34   0.27 
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]       34   0.27 
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       34   0.27 
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    34   0.27 
gi|163644325 MCF.2 cell line derived transforming sequence-like ...    34   0.27 
gi|163644323 MCF.2 cell line derived transforming sequence-like ...    34   0.27 
gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3...    34   0.35 
gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3...    34   0.35 
gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3...    34   0.35 
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    34   0.35 
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    34   0.35 

>gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens]
          Length = 499

 Score =  967 bits (2499), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF 60
           MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
Sbjct: 1   MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF 60

Query: 61  AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK 120
           AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
Sbjct: 61  AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK 120

Query: 121 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS 180
           RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
Sbjct: 121 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS 180

Query: 181 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN 240
           EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
Sbjct: 181 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN 240

Query: 241 LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT 300
           LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
Sbjct: 241 LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT 300

Query: 301 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR 360
           LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
Sbjct: 301 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR 360

Query: 361 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI 420
           KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
Sbjct: 361 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI 420

Query: 421 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF 480
           SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
Sbjct: 421 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF 480

Query: 481 SSMAEFLKVKGEKSGLMST 499
           SSMAEFLKVKGEKSGLMST
Sbjct: 481 SSMAEFLKVKGEKSGLMST 499


>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
          Length = 529

 Score =  129 bits (325), Expect = 5e-30
 Identities = 70/236 (29%), Positives = 129/236 (54%), Gaps = 2/236 (0%)

Query: 92  VIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKN 151
           +IV A +L  +++ ELN      R+ Y   FPEL  ++ + L Y + ++++G+   K   
Sbjct: 161 MIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDR--KNYA 218

Query: 152 NENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNASKHRIYEYVESR 211
           +  L ++L       V   A  + G ++SEE++  +   C   +E++  + ++YEY+++R
Sbjct: 219 SAKLSELLPEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNR 278

Query: 212 MSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLPHT 271
           M  IAPN+++++G    A+++  AG L NL+K  A  + +LGA++       S    P  
Sbjct: 279 MMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKY 338

Query: 272 GYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERK 327
           G IYH+ +V    P  + K +R++AAK  LA R D+F E +   +G E + ++E +
Sbjct: 339 GLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEAR 394


>gi|32483374 nucleolar protein 5A [Homo sapiens]
          Length = 594

 Score =  122 bits (307), Expect = 6e-28
 Identities = 74/304 (24%), Positives = 152/304 (50%), Gaps = 13/304 (4%)

Query: 92  VIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKN 151
           +I+ + +L  +++ ++N     +R+ Y   FPEL  ++ +   Y R  + +GN  +  ++
Sbjct: 167 MIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNED 226

Query: 152 N-ENLQQI-LTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNASKHRIYEYVE 209
             E L+++ +  A    +   + ++ G  +S  +L  +E      + L+  +  ++ Y+ 
Sbjct: 227 KLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLR 286

Query: 210 SRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLP 269
           S+MS +AP+LS +IG +  A+++  AG LTNL+K PA  + +LGA++       +    P
Sbjct: 287 SKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTP 346

Query: 270 HTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKFD 329
             G I+HS  +       + + +R +A KC++A+R+D F E      G +L++++E +  
Sbjct: 347 KYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLS 406

Query: 330 KWQ--EPP---------PVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRM 378
            ++  E P          + Q +   A +  + +K+  +R +K K+RL    +    N  
Sbjct: 407 FYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSS 466

Query: 379 SFGE 382
           S  E
Sbjct: 467 STPE 470


>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
          Length = 971

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 44/205 (21%), Positives = 92/205 (44%), Gaps = 27/205 (13%)

Query: 1   MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQ--LDLSGDSVKTIAKLWDSK 58
           ++ A++ +  L++   + E G    E    +++D QE  Q  LDL+ DS+K         
Sbjct: 425 LNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETK------ 478

Query: 59  MFAEIMMKIE-EYISKQAKASEVMGPVEAAPEYRVIVDANNLTVE-----------IENE 106
              + ++ +E E   ++ +  E +  ++   + +V   A++L ++           +  E
Sbjct: 479 ---DALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREE 535

Query: 107 LNIIHKFIRDKYSKRFPELESLVPNAL--DYIRTVKELGNSLDKCKNNENLQQILTNATI 164
           L + H+  +     +  +L+    NA    + + V++L N +   K N  +Q  L+ +  
Sbjct: 536 LRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQ--LSQSQT 593

Query: 165 MVVSVTASTTQGQQLSEEELERLEE 189
            +  + A  TQ +Q   +ELE LEE
Sbjct: 594 SLQQLQAQFTQERQRLTQELEELEE 618


>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
          Length = 1140

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 44/205 (21%), Positives = 92/205 (44%), Gaps = 27/205 (13%)

Query: 1   MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQ--LDLSGDSVKTIAKLWDSK 58
           ++ A++ +  L++   + E G    E    +++D QE  Q  LDL+ DS+K         
Sbjct: 545 LNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETK------ 598

Query: 59  MFAEIMMKIE-EYISKQAKASEVMGPVEAAPEYRVIVDANNLTVE-----------IENE 106
              + ++ +E E   ++ +  E +  ++   + +V   A++L ++           +  E
Sbjct: 599 ---DALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREE 655

Query: 107 LNIIHKFIRDKYSKRFPELESLVPNAL--DYIRTVKELGNSLDKCKNNENLQQILTNATI 164
           L + H+  +     +  +L+    NA    + + V++L N +   K N  +Q  L+ +  
Sbjct: 656 LRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQ--LSQSQT 713

Query: 165 MVVSVTASTTQGQQLSEEELERLEE 189
            +  + A  TQ +Q   +ELE LEE
Sbjct: 714 SLQQLQAQFTQERQRLTQELEELEE 738


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 37.0 bits (84), Expect = 0.042
 Identities = 47/187 (25%), Positives = 81/187 (43%), Gaps = 14/187 (7%)

Query: 17  EEEGGSYGEEEEEPAIEDVQEETQL----DLSGDSVKTIAKLWDSKMFAEIMMKIEEYIS 72
           E+E     ++ E    E VQE+  L    +LS D +K  A+L   K    +    E  I 
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL--EKTIETLRENSERQIK 554

Query: 73  KQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK--RFPELESLVP 130
              + +E +    ++   R  + A     +IE E  I+H+ I++  SK  +    +  + 
Sbjct: 555 ILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 614

Query: 131 NALDYIRT----VKELGNSLDKC-KNNENLQQILTNATIMVVSVTASTTQGQQLSEEELE 185
             L++ +      +EL N L    K NE LQ+ +TN  I    + A   +  +L E E  
Sbjct: 615 KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL-ERENR 673

Query: 186 RLEEACD 192
           +L++  D
Sbjct: 674 KLKKTLD 680


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 37.0 bits (84), Expect = 0.042
 Identities = 47/187 (25%), Positives = 81/187 (43%), Gaps = 14/187 (7%)

Query: 17  EEEGGSYGEEEEEPAIEDVQEETQL----DLSGDSVKTIAKLWDSKMFAEIMMKIEEYIS 72
           E+E     ++ E    E VQE+  L    +LS D +K  A+L   K    +    E  I 
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL--EKTIETLRENSERQIK 554

Query: 73  KQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK--RFPELESLVP 130
              + +E +    ++   R  + A     +IE E  I+H+ I++  SK  +    +  + 
Sbjct: 555 ILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 614

Query: 131 NALDYIRT----VKELGNSLDKC-KNNENLQQILTNATIMVVSVTASTTQGQQLSEEELE 185
             L++ +      +EL N L    K NE LQ+ +TN  I    + A   +  +L E E  
Sbjct: 615 KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL-ERENR 673

Query: 186 RLEEACD 192
           +L++  D
Sbjct: 674 KLKKTLD 680


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 36.2 bits (82), Expect = 0.071
 Identities = 52/201 (25%), Positives = 88/201 (43%), Gaps = 15/201 (7%)

Query: 6   ELLADLE-EAAEEEEGGSYGEEEEEPAIE---DVQEETQLDLSGDSVKTIAKLWDSKMFA 61
           EL+A+ + E  EE E G   +EEEE          +    DLS  S +      ++ +  
Sbjct: 302 ELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILE 361

Query: 62  EIMMKIEEYISKQAKASEVMG--PVEAAPEYRVIVDAN----NLTVEIENELNIIHKFIR 115
            +  K E   S+    S+++   P    PE + + D N    +  +E   EL+     I+
Sbjct: 362 SVSEKTERSNSEDKLNSKILNEKPTTDEPE-KAVEDINEHITDAQLEAMTELHDRTAVIK 420

Query: 116 DKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQ 175
           +   ++ P+LE+L P+  D   TV    NS+ + K N  +  + TN    + S      +
Sbjct: 421 ENEREKRPKLENL-PDTEDQ-ETVDI--NSVSEGKENNIMITLETNIEHNLKSEEEKDQE 476

Query: 176 GQQLSEEELERLEEACDMALE 196
            QQ+ E +L + EE  D  L+
Sbjct: 477 KQQMFENKLIKSEEIKDTILQ 497


>gi|109134336 SH3-domain binding protein 5 (BTK-associated) isoform
           a [Homo sapiens]
          Length = 455

 Score = 36.2 bits (82), Expect = 0.071
 Identities = 45/199 (22%), Positives = 83/199 (41%), Gaps = 24/199 (12%)

Query: 12  EEAAEEEEGGSYGEEEEEPAIEDVQEETQ-LDLSGDSV-KTIAKLWDSK-----MFAEIM 64
           +E  EEEEG   G EEEE     +Q E + L+ S D + +   +L D++     +  E  
Sbjct: 22  DEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEAT 81

Query: 65  MKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPE 124
           +K++E + K  KA E     ++ P +     A    +E +            K ++ F  
Sbjct: 82  VKLDELVKKIGKAVE-----DSKPYWEARRVARQAQLEAQ------------KATQDFQR 124

Query: 125 LESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEEL 184
              ++  A + I   ++     DK + +   Q++L +AT  V+    + T+ + + +E  
Sbjct: 125 ATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184

Query: 185 ERLEEACDMALELNASKHR 203
            R   A     +L     R
Sbjct: 185 ARYNAAMGRMRQLEKKLKR 203


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 35.8 bits (81), Expect = 0.093
 Identities = 22/48 (45%), Positives = 26/48 (54%)

Query: 6   ELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAK 53
           E L++ EE  EEEE     EEEEE   ED +   Q D SG S +  AK
Sbjct: 296 EQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAK 343


>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
           isoform a [Homo sapiens]
          Length = 1210

 Score = 35.8 bits (81), Expect = 0.093
 Identities = 22/48 (45%), Positives = 26/48 (54%)

Query: 6   ELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAK 53
           E L++ EE  EEEE     EEEEE   ED +   Q D SG S +  AK
Sbjct: 296 EQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAK 343


>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
          Length = 681

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 9/97 (9%)

Query: 7   LLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVK--------TIAKLWDSK 58
           LL + EE  E EE GS  E +++  +ED++EE   D+  D  +        + + L  S 
Sbjct: 106 LLPESEEQ-EREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSP 164

Query: 59  MFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVD 95
           +F++    ++  ISK  + S+V    +  P  + IVD
Sbjct: 165 VFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVD 201


>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
           sapiens]
          Length = 1205

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 20/151 (13%)

Query: 11  LEEAAEEE---EGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKI 67
           + E  +EE   EG   GEEEEE  +E+ ++E Q  +SG S+K + K   SKM  +  +K 
Sbjct: 404 ISETGDEEGLKEGD--GEEEEEEEVEEEEQEAQGGVSG-SLKGVPK--KSKMSLKQKIKK 458

Query: 68  E-EYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELE 126
           E E   +   ++  M  V   P YR+    + L+ + +N+           + +R     
Sbjct: 459 EPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQ-----------FMQRLHNYW 507

Query: 127 SLVPNALDYIRTVKELGNSLDKCKNNENLQQ 157
            L   A + +  ++ L + L   +N E  +Q
Sbjct: 508 LLKRQARNGVPLIRRLHSHLQSQRNAEQREQ 538


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 10/96 (10%)

Query: 5   DELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIM 64
           DE   + EE  EE+E     EEEEE   E+ +EE + +   +  +  A         +++
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA--------PDVI 312

Query: 65  MKIEEYISKQAKASEVMGPVEAA--PEYRVIVDANN 98
            + +   +   KA E+ GP   +  PEY VIV+  +
Sbjct: 313 FQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRS 348


>gi|68348702 breast cancer metastasis suppressor 1 isoform 2 [Homo
           sapiens]
          Length = 290

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 34/113 (30%), Positives = 55/113 (48%), Gaps = 11/113 (9%)

Query: 12  EEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKI-EEY 70
           EE +EEE  GS  E EEE +  ++ +E       + V  +  L   K F+E+  K+  E 
Sbjct: 27  EEESEEERSGSQTESEEESS--EMDDEDYERRRSECVSEMLDL--EKQFSELKEKLFRER 82

Query: 71  ISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHK-----FIRDKY 118
           +S+     E +G  E APEY   +     +++I  ++  I+K      IR+KY
Sbjct: 83  LSQLRLRLEEVG-AERAPEYTEPLGGLQRSLKIRIQVAGIYKGFCLDVIRNKY 134


>gi|17530785 breast cancer metastasis suppressor 1 isoform 1 [Homo
           sapiens]
          Length = 246

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 34/113 (30%), Positives = 55/113 (48%), Gaps = 11/113 (9%)

Query: 12  EEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKI-EEY 70
           EE +EEE  GS  E EEE +  ++ +E       + V  +  L   K F+E+  K+  E 
Sbjct: 27  EEESEEERSGSQTESEEESS--EMDDEDYERRRSECVSEMLDL--EKQFSELKEKLFRER 82

Query: 71  ISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHK-----FIRDKY 118
           +S+     E +G  E APEY   +     +++I  ++  I+K      IR+KY
Sbjct: 83  LSQLRLRLEEVG-AERAPEYTEPLGGLQRSLKIRIQVAGIYKGFCLDVIRNKY 134


>gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens]
          Length = 278

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 14/64 (21%), Positives = 34/64 (53%)

Query: 269 PHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKF 328
           P  G ++HS          + + ++ +A KC++A+++D F E      G +L++++E + 
Sbjct: 7   PKYGLVFHSTFTGQAAARNKGRISQYLANKCSIASQIDCFAEVLMSIFGEKLQEQVEERL 66

Query: 329 DKWQ 332
             ++
Sbjct: 67  SFYE 70


>gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens]
          Length = 278

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 14/64 (21%), Positives = 34/64 (53%)

Query: 269 PHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKF 328
           P  G ++HS          + + ++ +A KC++A+++D F E      G +L++++E + 
Sbjct: 7   PKYGLVFHSTFTGQAAARNKGRISQYLANKCSIASQIDCFAEVLMSIFGEKLQEQVEERL 66

Query: 329 DKWQ 332
             ++
Sbjct: 67  SFYE 70


>gi|239743692 PREDICTED: hypothetical protein LOC402360 [Homo
           sapiens]
          Length = 278

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 14/64 (21%), Positives = 34/64 (53%)

Query: 269 PHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKF 328
           P  G ++HS          + + ++ +A KC++A+++D F E      G +L++++E + 
Sbjct: 7   PKYGLVFHSTFTGQAAARNKGRISQYLANKCSIASQIDCFAEVLMSIFGEKLQEQVEERL 66

Query: 329 DKWQ 332
             ++
Sbjct: 67  SFYE 70


>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 44/224 (19%), Positives = 97/224 (43%), Gaps = 26/224 (11%)

Query: 7   LLADLEEAAEEEEGGSY-GEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF----- 60
           LL+D+EE  E+E   S  G+  ++ +++ +   +QL      ++   +  ++KM      
Sbjct: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401

Query: 61  -----AEIMMKI-------EEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELN 108
                 EI  K+       EE  S+Q   ++     E A E   ++        + NE  
Sbjct: 402 HELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETR 461

Query: 109 IIHKFIR---DKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIM 165
            +   +    D Y+ +  +L+  +  AL+Y+R  +++  +    + +   QQ      + 
Sbjct: 462 TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 521

Query: 166 VVSVTASTTQGQ----QLSEEELER-LEEACDMALELNASKHRI 204
           VV+++ ST+       +L+  EL+  ++ A  +  E++ +K  +
Sbjct: 522 VVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSEL 565


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 44/224 (19%), Positives = 97/224 (43%), Gaps = 26/224 (11%)

Query: 7   LLADLEEAAEEEEGGSY-GEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF----- 60
           LL+D+EE  E+E   S  G+  ++ +++ +   +QL      ++   +  ++KM      
Sbjct: 349 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 408

Query: 61  -----AEIMMKI-------EEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELN 108
                 EI  K+       EE  S+Q   ++     E A E   ++        + NE  
Sbjct: 409 HELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETR 468

Query: 109 IIHKFIR---DKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIM 165
            +   +    D Y+ +  +L+  +  AL+Y+R  +++  +    + +   QQ      + 
Sbjct: 469 TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 528

Query: 166 VVSVTASTTQGQ----QLSEEELER-LEEACDMALELNASKHRI 204
           VV+++ ST+       +L+  EL+  ++ A  +  E++ +K  +
Sbjct: 529 VVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSEL 572


>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 44/224 (19%), Positives = 97/224 (43%), Gaps = 26/224 (11%)

Query: 7   LLADLEEAAEEEEGGSY-GEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF----- 60
           LL+D+EE  E+E   S  G+  ++ +++ +   +QL      ++   +  ++KM      
Sbjct: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401

Query: 61  -----AEIMMKI-------EEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELN 108
                 EI  K+       EE  S+Q   ++     E A E   ++        + NE  
Sbjct: 402 HELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETR 461

Query: 109 IIHKFIR---DKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIM 165
            +   +    D Y+ +  +L+  +  AL+Y+R  +++  +    + +   QQ      + 
Sbjct: 462 TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 521

Query: 166 VVSVTASTTQGQ----QLSEEELER-LEEACDMALELNASKHRI 204
           VV+++ ST+       +L+  EL+  ++ A  +  E++ +K  +
Sbjct: 522 VVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSEL 565


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 10/116 (8%)

Query: 334 PPPVKQ-VKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDL 392
           PPP K  ++ LP+ L  +++KRG ++ ++ K   G    RK+ +       E D Y+E  
Sbjct: 90  PPPDKDDIRLLPSALGVKKRKRGPKKQKENKP--GKPRKRKKRDSEEEFGSERDEYREKS 147

Query: 393 GFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGT 448
                  G +G GR R+       K R  K  +   +K+    GG+  +  +SS T
Sbjct: 148 ESGGSEYG-TGPGRKRR------RKHREKKEKKTKRRKKGEGDGGQKQVEQKSSAT 196



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 16/34 (47%), Positives = 21/34 (61%)

Query: 5  DELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEE 38
          +E++   EE  EEEEG    EEE E A ED +E+
Sbjct: 13 EEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEED 46


>gi|163644325 MCF.2 cell line derived transforming sequence-like
           isoform a [Homo sapiens]
          Length = 1182

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 6/83 (7%)

Query: 108 NIIHKFIRDKYSKRFPELE-SLVPNALDYI---RTVKELGNSLDKCKNNENLQQILTNAT 163
           +I  KF RD +  + P +  S VP+   YI   +  ++LG +LD C +    Q+    + 
Sbjct: 205 DIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESF 264

Query: 164 IMVVSVTASTTQ--GQQLSEEEL 184
            ++V  TA   Q  G +L+E EL
Sbjct: 265 ALMVKQTAQMLQSFGTELAETEL 287


>gi|163644323 MCF.2 cell line derived transforming sequence-like
           isoform b [Homo sapiens]
          Length = 1129

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 6/83 (7%)

Query: 108 NIIHKFIRDKYSKRFPELE-SLVPNALDYI---RTVKELGNSLDKCKNNENLQQILTNAT 163
           +I  KF RD +  + P +  S VP+   YI   +  ++LG +LD C +    Q+    + 
Sbjct: 152 DIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESF 211

Query: 164 IMVVSVTASTTQ--GQQLSEEEL 184
            ++V  TA   Q  G +L+E EL
Sbjct: 212 ALMVKQTAQMLQSFGTELAETEL 234


>gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 9/97 (9%)

Query: 8   LADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQL-DLSGDSVKTIAK--------LWDSK 58
           L +  E  E EE GS  E   +  +ED+QEE ++ D+ GD+ +   K        L  S 
Sbjct: 27  LGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSP 86

Query: 59  MFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVD 95
           +F++    ++  ISK  + S+V       P  + I+D
Sbjct: 87  VFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIID 123


>gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 9/97 (9%)

Query: 8   LADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQL-DLSGDSVKTIAK--------LWDSK 58
           L +  E  E EE GS  E   +  +ED+QEE ++ D+ GD+ +   K        L  S 
Sbjct: 27  LGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSP 86

Query: 59  MFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVD 95
           +F++    ++  ISK  + S+V       P  + I+D
Sbjct: 87  VFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIID 123


>gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 9/97 (9%)

Query: 8   LADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQL-DLSGDSVKTIAK--------LWDSK 58
           L +  E  E EE GS  E   +  +ED+QEE ++ D+ GD+ +   K        L  S 
Sbjct: 27  LGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSP 86

Query: 59  MFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVD 95
           +F++    ++  ISK  + S+V       P  + I+D
Sbjct: 87  VFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIID 123


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 21/206 (10%)

Query: 12  EEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVK---------TIAKLWDSKMFAE 62
           E   EEEEG    EEE+E A  D  EE   +  G S K         T A+    +  A+
Sbjct: 524 EGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 583

Query: 63  IMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRF 122
              K+EE   + A   E++   +     +         VE + +  +    + +K     
Sbjct: 584 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 643

Query: 123 PEL------ESLVPNALDYIRTVKELGNS-LDKCKNNENLQQILTNATIMVVSVTASTTQ 175
           P+       +S VP +      V+E G S + K    E  +  +  + +      A   +
Sbjct: 644 PKSPVEEKGKSPVPKS-----PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGK 698

Query: 176 GQQLSEEELERLEEACDMALELNASK 201
           G+Q  EEE E  E   +  +E    K
Sbjct: 699 GEQKEEEEKEVKEAPKEEKVEKKEEK 724


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 21/206 (10%)

Query: 12  EEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVK---------TIAKLWDSKMFAE 62
           E   EEEEG    EEE+E A  D  EE   +  G S K         T A+    +  A+
Sbjct: 148 EGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 207

Query: 63  IMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRF 122
              K+EE   + A   E++   +     +         VE + +  +    + +K     
Sbjct: 208 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 267

Query: 123 PEL------ESLVPNALDYIRTVKELGNS-LDKCKNNENLQQILTNATIMVVSVTASTTQ 175
           P+       +S VP +      V+E G S + K    E  +  +  + +      A   +
Sbjct: 268 PKSPVEEKGKSPVPKS-----PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGK 322

Query: 176 GQQLSEEELERLEEACDMALELNASK 201
           G+Q  EEE E  E   +  +E    K
Sbjct: 323 GEQKEEEEKEVKEAPKEEKVEKKEEK 348


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,995,308
Number of Sequences: 37866
Number of extensions: 730827
Number of successful extensions: 4545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 4035
Number of HSP's gapped (non-prelim): 432
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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