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Search of human proteins with 22095388
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
sapiens]
(482 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo ... 961 0.0
gi|209862841 islet cell autoantigen 1 [Homo sapiens] 415 e-116
gi|94721350 islet cell autoantigen 1 [Homo sapiens] 415 e-116
gi|12545395 islet cell autoantigen 1 [Homo sapiens] 415 e-116
gi|30102946 islet cell autoantigen 1,69kDa-like isoform 2 [Homo ... 159 5e-39
gi|71040094 ADP-ribosylation factor interacting protein 1 isofor... 55 1e-07
gi|71040092 ADP-ribosylation factor interacting protein 1 isofor... 55 1e-07
gi|7657210 ADP-ribosylation factor interacting protein 1 isoform... 55 1e-07
gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo s... 44 3e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 41 0.002
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 41 0.002
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 41 0.002
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 41 0.002
gi|38044112 restin isoform b [Homo sapiens] 41 0.003
gi|4506751 restin isoform a [Homo sapiens] 41 0.003
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 40 0.006
gi|119874201 furry-like [Homo sapiens] 37 0.052
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 36 0.089
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 36 0.089
gi|71061468 centromere protein E [Homo sapiens] 34 0.26
gi|34577114 cytomatrix protein p110 [Homo sapiens] 34 0.26
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 34 0.34
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 34 0.34
gi|50083279 centrosome protein 4 [Homo sapiens] 34 0.34
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens] 34 0.34
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 33 0.75
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 32 0.98
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 32 0.98
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 32 1.3
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 32 1.3
>gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
sapiens]
Length = 482
Score = 961 bits (2485), Expect = 0.0
Identities = 482/482 (100%), Positives = 482/482 (100%)
Query: 1 MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60
MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ
Sbjct: 1 MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60
Query: 61 ETCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQR 120
ETCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQR
Sbjct: 61 ETCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQR 120
Query: 121 LALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQ 180
LALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQ
Sbjct: 121 LALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQ 180
Query: 181 MEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTAR 240
MEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTAR
Sbjct: 181 MEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTAR 240
Query: 241 MMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFE 300
MMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFE
Sbjct: 241 MMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFE 300
Query: 301 SEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSS 360
SEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSS
Sbjct: 301 SEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSS 360
Query: 361 TSEFTQECQTAFGSPSASLTSQEPSMGSEPLAHSSRFLPSQLFDLGFHVAGAFNNWVSQE 420
TSEFTQECQTAFGSPSASLTSQEPSMGSEPLAHSSRFLPSQLFDLGFHVAGAFNNWVSQE
Sbjct: 361 TSEFTQECQTAFGSPSASLTSQEPSMGSEPLAHSSRFLPSQLFDLGFHVAGAFNNWVSQE 420
Query: 421 ESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLDPLSNPDAIGHSDDELL 480
ESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLDPLSNPDAIGHSDDELL
Sbjct: 421 ESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLDPLSNPDAIGHSDDELL 480
Query: 481 NA 482
NA
Sbjct: 481 NA 482
>gi|209862841 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 415 bits (1066), Expect = e-116
Identities = 243/500 (48%), Positives = 305/500 (61%), Gaps = 52/500 (10%)
Query: 6 QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
Q R ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72
Query: 66 LLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCT 125
L K I YQ R+ +S+EENELG FL+ Q +D T+AGKMM ATGKALC S++QRLAL
Sbjct: 73 LSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRN 132
Query: 126 PLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFR 185
PL R QEV TF RA+SDT +T+NRMEQ RTEYRGALLWMKDVSQELDPD KQMEKFR
Sbjct: 133 PLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFR 192
Query: 186 KVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQI 245
KVQ QVR +K +FDKLKMDVCQKVDLLGASRCN+LSH L TYQ TLL FW+KT+ M+ I
Sbjct: 193 KVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAI 252
Query: 246 HEACIGFHPYDFVALKQLQDTPSKISED------NKDEQIGGFLTEQLNKLVLSDEEASF 299
HE+ G+ PY+F LK LQD K+ E N+ E + E + L +E
Sbjct: 253 HESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRK 312
Query: 300 ESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEG------------EDFEK-E 346
ES + + + G+ + S + + L + S EG E +K +
Sbjct: 313 ESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDD 372
Query: 347 FSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGS-EPLAHS-SRFLPSQLFD 404
L+ + ++ S EF++E FG ++G +P A + S FLPSQL D
Sbjct: 373 LLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLD 432
Query: 405 LGFHVAGAFNNWVSQEESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLD 464
Q +L S + P D++AWF+LFADLD
Sbjct: 433 --------------QNMKDLQAS---------------LQEPAKAASDLTAWFSLFADLD 463
Query: 465 PLSNPDAIGHSD--DELLNA 482
PLSNPDA+G +D ELLNA
Sbjct: 464 PLSNPDAVGKTDKEHELLNA 483
>gi|94721350 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 415 bits (1066), Expect = e-116
Identities = 243/500 (48%), Positives = 305/500 (61%), Gaps = 52/500 (10%)
Query: 6 QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
Q R ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72
Query: 66 LLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCT 125
L K I YQ R+ +S+EENELG FL+ Q +D T+AGKMM ATGKALC S++QRLAL
Sbjct: 73 LSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRN 132
Query: 126 PLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFR 185
PL R QEV TF RA+SDT +T+NRMEQ RTEYRGALLWMKDVSQELDPD KQMEKFR
Sbjct: 133 PLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFR 192
Query: 186 KVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQI 245
KVQ QVR +K +FDKLKMDVCQKVDLLGASRCN+LSH L TYQ TLL FW+KT+ M+ I
Sbjct: 193 KVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAI 252
Query: 246 HEACIGFHPYDFVALKQLQDTPSKISED------NKDEQIGGFLTEQLNKLVLSDEEASF 299
HE+ G+ PY+F LK LQD K+ E N+ E + E + L +E
Sbjct: 253 HESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRK 312
Query: 300 ESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEG------------EDFEK-E 346
ES + + + G+ + S + + L + S EG E +K +
Sbjct: 313 ESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDD 372
Query: 347 FSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGS-EPLAHS-SRFLPSQLFD 404
L+ + ++ S EF++E FG ++G +P A + S FLPSQL D
Sbjct: 373 LLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLD 432
Query: 405 LGFHVAGAFNNWVSQEESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLD 464
Q +L S + P D++AWF+LFADLD
Sbjct: 433 --------------QNMKDLQAS---------------LQEPAKAASDLTAWFSLFADLD 463
Query: 465 PLSNPDAIGHSD--DELLNA 482
PLSNPDA+G +D ELLNA
Sbjct: 464 PLSNPDAVGKTDKEHELLNA 483
>gi|12545395 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 415 bits (1066), Expect = e-116
Identities = 243/500 (48%), Positives = 305/500 (61%), Gaps = 52/500 (10%)
Query: 6 QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
Q R ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72
Query: 66 LLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCT 125
L K I YQ R+ +S+EENELG FL+ Q +D T+AGKMM ATGKALC S++QRLAL
Sbjct: 73 LSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRN 132
Query: 126 PLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFR 185
PL R QEV TF RA+SDT +T+NRMEQ RTEYRGALLWMKDVSQELDPD KQMEKFR
Sbjct: 133 PLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFR 192
Query: 186 KVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQI 245
KVQ QVR +K +FDKLKMDVCQKVDLLGASRCN+LSH L TYQ TLL FW+KT+ M+ I
Sbjct: 193 KVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAI 252
Query: 246 HEACIGFHPYDFVALKQLQDTPSKISED------NKDEQIGGFLTEQLNKLVLSDEEASF 299
HE+ G+ PY+F LK LQD K+ E N+ E + E + L +E
Sbjct: 253 HESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRK 312
Query: 300 ESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEG------------EDFEK-E 346
ES + + + G+ + S + + L + S EG E +K +
Sbjct: 313 ESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDD 372
Query: 347 FSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGS-EPLAHS-SRFLPSQLFD 404
L+ + ++ S EF++E FG ++G +P A + S FLPSQL D
Sbjct: 373 LLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLD 432
Query: 405 LGFHVAGAFNNWVSQEESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLD 464
Q +L S + P D++AWF+LFADLD
Sbjct: 433 --------------QNMKDLQAS---------------LQEPAKAASDLTAWFSLFADLD 463
Query: 465 PLSNPDAIGHSD--DELLNA 482
PLSNPDA+G +D ELLNA
Sbjct: 464 PLSNPDAVGKTDKEHELLNA 483
>gi|30102946 islet cell autoantigen 1,69kDa-like isoform 2 [Homo
sapiens]
Length = 82
Score = 159 bits (402), Expect = 5e-39
Identities = 78/78 (100%), Positives = 78/78 (100%)
Query: 1 MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60
MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ
Sbjct: 1 MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60
Query: 61 ETCTELLKIIEKYQLRLN 78
ETCTELLKIIEKYQLRLN
Sbjct: 61 ETCTELLKIIEKYQLRLN 78
>gi|71040094 ADP-ribosylation factor interacting protein 1 isoform 1
[Homo sapiens]
Length = 373
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/246 (21%), Positives = 103/246 (41%), Gaps = 13/246 (5%)
Query: 2 DSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQE 61
D P E + V + Y T+Q+ + G+ D EL+A++++ ++
Sbjct: 115 DEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSR----TVDLELEAQIDILRDNKK 170
Query: 62 TCTELLKIIEKYQLRLNVISEEENELG---LFLKFQAERDATQAGKMMDATGKALCSSAK 118
+LK+ + +L + + +LG L ++ + G D T K L AK
Sbjct: 171 KYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-TQKLL---AK 226
Query: 119 QRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTL 178
L ++ V T + + DTLMT+ + E AR EY +++++ L P
Sbjct: 227 NGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDA 284
Query: 179 KQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKT 238
+ K + Q + K +DK++ DV K+ L ++ +L + L + + ++
Sbjct: 285 NTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGN 344
Query: 239 ARMMSQ 244
+ + Q
Sbjct: 345 QKQLEQ 350
>gi|71040092 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/246 (21%), Positives = 103/246 (41%), Gaps = 13/246 (5%)
Query: 2 DSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQE 61
D P E + V + Y T+Q+ + G+ D EL+A++++ ++
Sbjct: 83 DEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSR----TVDLELEAQIDILRDNKK 138
Query: 62 TCTELLKIIEKYQLRLNVISEEENELG---LFLKFQAERDATQAGKMMDATGKALCSSAK 118
+LK+ + +L + + +LG L ++ + G D T K L AK
Sbjct: 139 KYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-TQKLL---AK 194
Query: 119 QRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTL 178
L ++ V T + + DTLMT+ + E AR EY +++++ L P
Sbjct: 195 NGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDA 252
Query: 179 KQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKT 238
+ K + Q + K +DK++ DV K+ L ++ +L + L + + ++
Sbjct: 253 NTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGN 312
Query: 239 ARMMSQ 244
+ + Q
Sbjct: 313 QKQLEQ 318
>gi|7657210 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/246 (21%), Positives = 103/246 (41%), Gaps = 13/246 (5%)
Query: 2 DSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQE 61
D P E + V + Y T+Q+ + G+ D EL+A++++ ++
Sbjct: 83 DEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSR----TVDLELEAQIDILRDNKK 138
Query: 62 TCTELLKIIEKYQLRLNVISEEENELG---LFLKFQAERDATQAGKMMDATGKALCSSAK 118
+LK+ + +L + + +LG L ++ + G D T K L AK
Sbjct: 139 KYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-TQKLL---AK 194
Query: 119 QRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTL 178
L ++ V T + + DTLMT+ + E AR EY +++++ L P
Sbjct: 195 NGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDA 252
Query: 179 KQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKT 238
+ K + Q + K +DK++ DV K+ L ++ +L + L + + ++
Sbjct: 253 NTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGN 312
Query: 239 ARMMSQ 244
+ + Q
Sbjct: 313 QKQLEQ 318
>gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo
sapiens]
Length = 341
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/201 (19%), Positives = 83/201 (41%), Gaps = 7/201 (3%)
Query: 46 DAELDAKLEVFHSVQETCTELLKIIEKYQLRLNVISEEENELG-LFLKFQAERDATQAGK 104
D EL+ ++E+ + +L++ L + + ++ LG F + Q
Sbjct: 123 DLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEF 182
Query: 105 MMDA-TGKALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGAL 163
+A T K LC + + L ++ + T + + DTLMT+ + E AR EY
Sbjct: 183 GYNAETQKLLCKNGETLLGA---VNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYR 239
Query: 164 LWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHS 223
++++S L P + Q + + ++KL+ DV K+ L ++ ++
Sbjct: 240 TDLEELS--LGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQ 297
Query: 224 LTTYQRTLLGFWKKTARMMSQ 244
L + + ++ + + Q
Sbjct: 298 LLLFHNAVSAYFAGNQKQLEQ 318
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/410 (18%), Positives = 163/410 (39%), Gaps = 40/410 (9%)
Query: 16 VRRMQKKYWKTKQVFIKATGKKEDEHLVASDAEL---DAKLEVFHSVQETCTELLKIIEK 72
+++ +K + +++ K G D H +D + + K+++ +E L ++ ++
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 73 YQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPLSRLKQ 132
+ N + + G Q + D+ +A + + K ++ AL T L
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAAR--NKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 133 EVATFSQ-RAVSDTLMTINR--MEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQM 189
AT + RA + +T+ + +++ + + M+ + + +Q+E+F++ +
Sbjct: 1161 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1220
Query: 190 QVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHEAC 249
+ +K + +K D+ ++ +LG ++ + H KK + ++ C
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAK-QEVEHKK-----------KKLEAQVQELQSKC 1268
Query: 250 IGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLV-LSDEEASFESEQANKDH 308
A +L D K+ N+ E + G L E K + L+ + AS S+ +
Sbjct: 1269 SDGER----ARAELNDKVHKL--QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 309 NEKHSQMREFGAP----QFSNSENVAKDLPVDSLEG-EDFEKEFSFLNNLLSSGS----- 358
+ ++ Q N +D + +E ++ E+ S LN LS
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 359 -SSTSEFTQECQTAFGSPSASLTSQ--EPSMGSEPLAHSSRFLPSQLFDL 405
+ST E +E + F +LT Q E + + L + L +L DL
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/410 (18%), Positives = 163/410 (39%), Gaps = 40/410 (9%)
Query: 16 VRRMQKKYWKTKQVFIKATGKKEDEHLVASDAEL---DAKLEVFHSVQETCTELLKIIEK 72
+++ +K + +++ K G D H +D + + K+++ +E L ++ ++
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 73 YQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPLSRLKQ 132
+ N + + G Q + D+ +A + + K ++ AL T L
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDLDSERAAR--NKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 133 EVATFSQ-RAVSDTLMTINR--MEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQM 189
AT + RA + +T+ + +++ + + M+ + + +Q+E+F++ +
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1227
Query: 190 QVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHEAC 249
+ +K + +K D+ ++ +LG ++ + H KK + ++ C
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAK-QEVEHKK-----------KKLEAQVQELQSKC 1275
Query: 250 IGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLV-LSDEEASFESEQANKDH 308
A +L D K+ N+ E + G L E K + L+ + AS S+ +
Sbjct: 1276 SDGER----ARAELNDKVHKL--QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 309 NEKHSQMREFGAP----QFSNSENVAKDLPVDSLEG-EDFEKEFSFLNNLLSSGS----- 358
+ ++ Q N +D + +E ++ E+ S LN LS
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 359 -SSTSEFTQECQTAFGSPSASLTSQ--EPSMGSEPLAHSSRFLPSQLFDL 405
+ST E +E + F +LT Q E + + L + L +L DL
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/410 (18%), Positives = 163/410 (39%), Gaps = 40/410 (9%)
Query: 16 VRRMQKKYWKTKQVFIKATGKKEDEHLVASDAEL---DAKLEVFHSVQETCTELLKIIEK 72
+++ +K + +++ K G D H +D + + K+++ +E L ++ ++
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 73 YQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPLSRLKQ 132
+ N + + G Q + D+ +A + + K ++ AL T L
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDLDSERAAR--NKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 133 EVATFSQ-RAVSDTLMTINR--MEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQM 189
AT + RA + +T+ + +++ + + M+ + + +Q+E+F++ +
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1227
Query: 190 QVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHEAC 249
+ +K + +K D+ ++ +LG ++ + H KK + ++ C
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAK-QEVEHKK-----------KKLEAQVQELQSKC 1275
Query: 250 IGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLV-LSDEEASFESEQANKDH 308
A +L D K+ N+ E + G L E K + L+ + AS S+ +
Sbjct: 1276 SDGER----ARAELNDKVHKL--QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 309 NEKHSQMREFGAP----QFSNSENVAKDLPVDSLEG-EDFEKEFSFLNNLLSSGS----- 358
+ ++ Q N +D + +E ++ E+ S LN LS
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 359 -SSTSEFTQECQTAFGSPSASLTSQ--EPSMGSEPLAHSSRFLPSQLFDL 405
+ST E +E + F +LT Q E + + L + L +L DL
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/410 (18%), Positives = 163/410 (39%), Gaps = 40/410 (9%)
Query: 16 VRRMQKKYWKTKQVFIKATGKKEDEHLVASDAEL---DAKLEVFHSVQETCTELLKIIEK 72
+++ +K + +++ K G D H +D + + K+++ +E L ++ ++
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 73 YQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPLSRLKQ 132
+ N + + G Q + D+ +A + + K ++ AL T L
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAAR--NKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 133 EVATFSQ-RAVSDTLMTINR--MEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQM 189
AT + RA + +T+ + +++ + + M+ + + +Q+E+F++ +
Sbjct: 1161 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1220
Query: 190 QVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHEAC 249
+ +K + +K D+ ++ +LG ++ + H KK + ++ C
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAK-QEVEHKK-----------KKLEAQVQELQSKC 1268
Query: 250 IGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLV-LSDEEASFESEQANKDH 308
A +L D K+ N+ E + G L E K + L+ + AS S+ +
Sbjct: 1269 SDGER----ARAELNDKVHKL--QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 309 NEKHSQMREFGAP----QFSNSENVAKDLPVDSLEG-EDFEKEFSFLNNLLSSGS----- 358
+ ++ Q N +D + +E ++ E+ S LN LS
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 359 -SSTSEFTQECQTAFGSPSASLTSQ--EPSMGSEPLAHSSRFLPSQLFDL 405
+ST E +E + F +LT Q E + + L + L +L DL
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 40.8 bits (94), Expect = 0.003
Identities = 66/303 (21%), Positives = 124/303 (40%), Gaps = 40/303 (13%)
Query: 36 KKEDEHLVASD------AELDAKLEVFHSVQETCTELLKIIEKYQLRLNVISEEENELGL 89
K ED+HLV + E + K++ +Q C E K+I+ + +L E+
Sbjct: 673 KAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEK------ 726
Query: 90 FLKFQAERDATQAGKM-MDATGKALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMT 148
L A R A+ GK M + L ++ KQ + L+ E S +A S T
Sbjct: 727 LLDLDALRKASSEGKSEMKKLRQQLEAAEKQ-------IKHLEIEKNAESSKASSIT-RE 778
Query: 149 INRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQK 208
+ E T + L + V + L+ + EKF + + + + S + + QK
Sbjct: 779 LQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQK 838
Query: 209 VDLLGASRCNMLSHSLTTYQRTLLGF---WKKTARMMSQIHEACIGFHPYDFVALKQLQD 265
+ + NMLS L + L +++ Q+ +A +K D
Sbjct: 839 EE-----QFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD 893
Query: 266 TPSKISEDNKDEQIGGFLTEQLN-KLVLSDEEASF----------ESEQANKDHNEKHSQ 314
S++++ N + ++ E+L KL ++E ASF ++EQ+ ++ +KH +
Sbjct: 894 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 953
Query: 315 MRE 317
++
Sbjct: 954 EKK 956
Score = 31.2 bits (69), Expect = 2.2
Identities = 73/366 (19%), Positives = 143/366 (39%), Gaps = 60/366 (16%)
Query: 10 EDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASD--------AELDAKLEVFHSVQE 61
E+ SV R MQ+ K Q K+E ++++SD A+++AK F E
Sbjct: 819 EEAVSVQRSMQETVNKLHQ-------KEEQFNMLSSDLEKLRENLADMEAK---FREKDE 868
Query: 62 TCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRL 121
+L+K EK EN++ +K + +++Q KM D + +L
Sbjct: 869 REEQLIKAKEKL----------ENDIAEIMKMSGD-NSSQLTKMNDELRLKERDVEELQL 917
Query: 122 ALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQM 181
L E A+F Q+++ D MT+ + EQ++ E A ++ +EL+
Sbjct: 918 KLTKA-----NENASFLQKSIED--MTV-KAEQSQQE---AAKKHEEEKKELERKLSDLE 966
Query: 182 EKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARM 241
+K Q + KA +++ + K + + L +L + L G ++ + +
Sbjct: 967 KKMETSHNQCQELKARYERATSETKTKHEEI----LQNLQKTLLDTEDKLKGAREENSGL 1022
Query: 242 MSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFES 301
+ ++ E L++ D QI +T++ + + S E+ +
Sbjct: 1023 LQELEE------------LRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLED----T 1066
Query: 302 EQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSST 361
+Q N + ++E + L V++ + E+F KE L + S
Sbjct: 1067 KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQL 1126
Query: 362 SEFTQE 367
S +E
Sbjct: 1127 SALQEE 1132
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 40.8 bits (94), Expect = 0.003
Identities = 66/303 (21%), Positives = 124/303 (40%), Gaps = 40/303 (13%)
Query: 36 KKEDEHLVASD------AELDAKLEVFHSVQETCTELLKIIEKYQLRLNVISEEENELGL 89
K ED+HLV + E + K++ +Q C E K+I+ + +L E+
Sbjct: 708 KAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEK------ 761
Query: 90 FLKFQAERDATQAGKM-MDATGKALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMT 148
L A R A+ GK M + L ++ KQ + L+ E S +A S T
Sbjct: 762 LLDLDALRKASSEGKSEMKKLRQQLEAAEKQ-------IKHLEIEKNAESSKASSIT-RE 813
Query: 149 INRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQK 208
+ E T + L + V + L+ + EKF + + + + S + + QK
Sbjct: 814 LQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQK 873
Query: 209 VDLLGASRCNMLSHSLTTYQRTLLGF---WKKTARMMSQIHEACIGFHPYDFVALKQLQD 265
+ + NMLS L + L +++ Q+ +A +K D
Sbjct: 874 EE-----QFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD 928
Query: 266 TPSKISEDNKDEQIGGFLTEQLN-KLVLSDEEASF----------ESEQANKDHNEKHSQ 314
S++++ N + ++ E+L KL ++E ASF ++EQ+ ++ +KH +
Sbjct: 929 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 988
Query: 315 MRE 317
++
Sbjct: 989 EKK 991
Score = 31.2 bits (69), Expect = 2.2
Identities = 73/366 (19%), Positives = 143/366 (39%), Gaps = 60/366 (16%)
Query: 10 EDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASD--------AELDAKLEVFHSVQE 61
E+ SV R MQ+ K Q K+E ++++SD A+++AK F E
Sbjct: 854 EEAVSVQRSMQETVNKLHQ-------KEEQFNMLSSDLEKLRENLADMEAK---FREKDE 903
Query: 62 TCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRL 121
+L+K EK EN++ +K + +++Q KM D + +L
Sbjct: 904 REEQLIKAKEKL----------ENDIAEIMKMSGD-NSSQLTKMNDELRLKERDVEELQL 952
Query: 122 ALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQM 181
L E A+F Q+++ D MT+ + EQ++ E A ++ +EL+
Sbjct: 953 KLTKA-----NENASFLQKSIED--MTV-KAEQSQQE---AAKKHEEEKKELERKLSDLE 1001
Query: 182 EKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARM 241
+K Q + KA +++ + K + + L +L + L G ++ + +
Sbjct: 1002 KKMETSHNQCQELKARYERATSETKTKHEEI----LQNLQKTLLDTEDKLKGAREENSGL 1057
Query: 242 MSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFES 301
+ ++ E L++ D QI +T++ + + S E+ +
Sbjct: 1058 LQELEE------------LRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLED----T 1101
Query: 302 EQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSST 361
+Q N + ++E + L V++ + E+F KE L + S
Sbjct: 1102 KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQL 1161
Query: 362 SEFTQE 367
S +E
Sbjct: 1162 SALQEE 1167
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 39.7 bits (91), Expect = 0.006
Identities = 72/313 (23%), Positives = 125/313 (39%), Gaps = 32/313 (10%)
Query: 13 QSVVRRMQKKYWKTKQVFIKATGKKED--EHLVASDAELDAKLEVFHSVQETCTELLKII 70
Q+ ++ Q++ K + T K +D EH ++ L E + S+++ EL I
Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 71 EKYQL-RLNVISEEENELGLF-----LKFQAERDATQAGKMMDATGKALCS--------- 115
+K + L V + +E L L E AT+ K ++ + + S
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 116 ----SAKQRLALCTPLSR-LKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVS 170
S KQ+L + LKQ+ T SQ NR++ TE + + + +
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852
Query: 171 QELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASR-CNMLSHSLTTYQR 229
EL T+K +K KV ++NSK+ F+K K +L + C L H L
Sbjct: 853 TELS--TVK--DKLSKVSDSLKNSKSEFEKENQK--GKAAILDLEKTCKELKHQLQVQME 906
Query: 230 TLLGFWKKTARMMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNK 289
L K+ + + + EA +QL + + ++ K+EQ L +N+
Sbjct: 907 NTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQ---QLQGNINE 963
Query: 290 LVLSDEEASFESE 302
L S E+ + E
Sbjct: 964 LKQSSEQKKKQIE 976
>gi|119874201 furry-like [Homo sapiens]
Length = 3013
Score = 36.6 bits (83), Expect = 0.052
Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 13/122 (10%)
Query: 263 LQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFESEQANKDHNEKHSQMREFGAPQ 322
L PS + N+D ++G +Q L+ + E+ + E E A +D++ + ++FG
Sbjct: 2375 LPKNPSVVFSSNEDLEVG----DQQTSLISTTEDINQEEEVAVEDNSSE----QQFGV-- 2424
Query: 323 FSNSENVAKDLPVDSLEGEDFEK-EFSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTS 381
F + + + D+ ++ EGE + + L S + QE Q + +PS +LT+
Sbjct: 2425 FKDFDFL--DVELEDAEGESMDNFNWGVRRRSLDSIDKGDTPSLQEYQCSSSTPSLNLTN 2482
Query: 382 QE 383
QE
Sbjct: 2483 QE 2484
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 35.8 bits (81), Expect = 0.089
Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 17/177 (9%)
Query: 297 ASF-ESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLS 355
ASF +S +KD + + E G+ Q + A PV L+ E F+ +
Sbjct: 816 ASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ-EKLSPFFTLDLSPTE 874
Query: 356 SGSSSTSEFTQECQTAFGSPSASLTSQEPSMG-SEPLAHSSRFLPSQLFDLGFHVAGAFN 414
SS S FT++ AF S+ PSM SEP+ S LP ++ + V G +
Sbjct: 875 DKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPI---SVTLPPRVSE----VIGTVS 927
Query: 415 NWVSQEES----ELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLDPLS 467
N +Q S + C+ D ++SP ++ + N A+ + LD ++
Sbjct: 928 NTTAQNASSSTWDKCVEERD---ATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVA 981
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 35.8 bits (81), Expect = 0.089
Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 17/177 (9%)
Query: 297 ASF-ESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLS 355
ASF +S +KD + + E G+ Q + A PV L+ E F+ +
Sbjct: 467 ASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ-EKLSPFFTLDLSPTE 525
Query: 356 SGSSSTSEFTQECQTAFGSPSASLTSQEPSMG-SEPLAHSSRFLPSQLFDLGFHVAGAFN 414
SS S FT++ AF S+ PSM SEP+ S LP ++ + V G +
Sbjct: 526 DKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPI---SVTLPPRVSE----VIGTVS 578
Query: 415 NWVSQEES----ELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLDPLS 467
N +Q S + C+ D ++SP ++ + N A+ + LD ++
Sbjct: 579 NTTAQNASSSTWDKCVEERD---ATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVA 632
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 34.3 bits (77), Expect = 0.26
Identities = 69/314 (21%), Positives = 123/314 (39%), Gaps = 40/314 (12%)
Query: 10 EDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKI 69
E+ + +V +M++ K Q F+K T E + + E+ H ++ T+ L +
Sbjct: 1611 ENTKEIVAKMKESQEKEYQ-FLKMTAVNETQEKMC---------EIEHLKEQFETQKLNL 1660
Query: 70 --IEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPL 127
IE +RL I E E ERD ++ ++ T K K+ L
Sbjct: 1661 ENIETENIRLTQILHENLEE--MRSVTKERDDLRS---VEETLKVERDQLKENLRETITR 1715
Query: 128 SRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWM-KDVSQELDP---DTLKQMEK 183
KQE + + TI+++ +E + M KD+ D LK E+
Sbjct: 1716 DLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEE 1775
Query: 184 FRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMS 243
R M ++ + + DKL+ V +K D L+ Q+ L A++
Sbjct: 1776 LRIAHMHLKEQQETIDKLRGIVSEKTD------------KLSNMQKDL---ENSNAKLQE 1820
Query: 244 QIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFESEQ 303
+I E H K + +T K+SE EQ+ + +Q L + E +++
Sbjct: 1821 KIQELKANEHQL-ITLKKDVNETQKKVSE---MEQLKKQIKDQSLTLSKLEIENLNLAQK 1876
Query: 304 ANKDHNEKHSQMRE 317
+++ E S M+E
Sbjct: 1877 LHENLEEMKSVMKE 1890
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 34.3 bits (77), Expect = 0.26
Identities = 67/339 (19%), Positives = 139/339 (41%), Gaps = 69/339 (20%)
Query: 10 EDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKI 69
E Q V + K+ KTK +K K++ L+A L KLE + C + +++
Sbjct: 418 EIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLA----LQTKLETLSNQNSDCKQHIEV 473
Query: 70 IEKY----QLRLNVISEEENELGLFLKFQ--------------AERDATQAGKMMDATG- 110
+++ + R ++ E + L L L+ + E T AG++ D
Sbjct: 474 LKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDM 533
Query: 111 ------------KALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTE 158
K + + +Q L+ LK V + Q S+T + +E+A +E
Sbjct: 534 LEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSL-QTDSSNTDTALATLEEALSE 592
Query: 159 YRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCN 218
+ +K+ + D + L+++E FRK + ++ K + L+ ++ +K +S +
Sbjct: 593 KERIIERLKEQRERDDRERLEEIESFRK---ENKDLKEKVNALQAELTEK----ESSLID 645
Query: 219 MLSHSLTTYQRTLLGFWKKTARMMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNK--- 275
+ H+ + L K+ +++ S +A++Q ++ SK+ K
Sbjct: 646 LKEHASSLASAGL----KRDSKLKSL------------EIAIEQKKEECSKLEAQLKKAH 689
Query: 276 ----DEQIGGFLTEQLNKLVLSDEEASFESEQANKDHNE 310
D ++ +Q+ +L D+EAS+ ++ K E
Sbjct: 690 NIEDDSRMNPEFADQIKQL---DKEASYYRDECGKAQAE 725
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 33.9 bits (76), Expect = 0.34
Identities = 54/226 (23%), Positives = 93/226 (41%), Gaps = 28/226 (12%)
Query: 36 KKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIE-KYQLRLNVISEEENELGLFLKFQ 94
K++ HL +L+ ++ V T E L +++ ++Q + E++ + LK
Sbjct: 4244 KEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQS 4303
Query: 95 AERDATQAGKMMDATGKALCSS--AKQRL--ALCTPLSRLKQEVATFS----QRAVSDTL 146
D Q +MD A+CS AKQ L +L R+ ++ Q+A+SD
Sbjct: 4304 PPPDMAQ-NLLMDHL--AICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQ 4360
Query: 147 MTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKV-QMQVRNSKASFDK----L 201
+N + + R K +++ L T M F+ Q+Q K F + L
Sbjct: 4361 SHVNCLSDLVGQRR------KYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLL 4414
Query: 202 KMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHE 247
DV ++V C SL TYQ + G W + +M ++ E
Sbjct: 4415 PDDVSKQV-----KTCKSAQASLKTYQNEVTGLWAQGRELMKEVTE 4455
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 33.9 bits (76), Expect = 0.34
Identities = 54/226 (23%), Positives = 93/226 (41%), Gaps = 28/226 (12%)
Query: 36 KKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIE-KYQLRLNVISEEENELGLFLKFQ 94
K++ HL +L+ ++ V T E L +++ ++Q + E++ + LK
Sbjct: 4315 KEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQS 4374
Query: 95 AERDATQAGKMMDATGKALCSS--AKQRL--ALCTPLSRLKQEVATFS----QRAVSDTL 146
D Q +MD A+CS AKQ L +L R+ ++ Q+A+SD
Sbjct: 4375 PPPDMAQ-NLLMDHL--AICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQ 4431
Query: 147 MTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKV-QMQVRNSKASFDK----L 201
+N + + R K +++ L T M F+ Q+Q K F + L
Sbjct: 4432 SHVNCLSDLVGQRR------KYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLL 4485
Query: 202 KMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHE 247
DV ++V C SL TYQ + G W + +M ++ E
Sbjct: 4486 PDDVSKQV-----KTCKSAQASLKTYQNEVTGLWAQGRELMKEVTE 4526
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 33.9 bits (76), Expect = 0.34
Identities = 36/165 (21%), Positives = 69/165 (41%), Gaps = 9/165 (5%)
Query: 48 ELDAKLEVFHSVQETCTELLKIIEKYQLRLNVI-SEEENELGLFLKFQAERDATQAGKMM 106
EL LE F E +K++ + +L+V+ +E + EL K + A +
Sbjct: 507 ELQRMLERFEKYMEDIQSNVKLLTAERDKLSVLYNEAQEELSALRKESTQTTAPHNIVSL 566
Query: 107 DATGKALCSSAKQRLALCTPLSRLK----QEVATFSQRAVSDTLMTI----NRMEQARTE 158
K L S +R+ R K +EV+ F + + T+ + +++E + E
Sbjct: 567 MEKEKELALSDLRRIMAEKEALREKLEHIEEVSLFGKSELEKTIEHLTCVNHQLESEKYE 626
Query: 159 YRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKM 203
+ +L MK+ + L+ Q +KF V + K + L++
Sbjct: 627 LKSKVLIMKETIESLENKLKVQAQKFSHVAGDSSHQKTEVNSLRI 671
>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
Length = 1178
Score = 33.9 bits (76), Expect = 0.34
Identities = 79/395 (20%), Positives = 159/395 (40%), Gaps = 41/395 (10%)
Query: 7 PRPEDNQSVV-RRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
P P+D +V R Q++ +++ +K +K + +++ +V +T E
Sbjct: 334 PIPQDGLTVAPHRAQREAVHIEKIMLKGVQRKRADKYWEYTFKVNWSDLSVTTVTKTHQE 393
Query: 66 LLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCT 125
L + + K L+ + ++ L + +R+ + + + SS++ L
Sbjct: 394 LQEFLLKLPKELSSETFDKTILRALNQGSLKREERRHPDLEPILRQLFSSSSQAFLQ--- 450
Query: 126 PLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFR 185
Q+V +F Q SD+L +IN ++ + L + + L D+ + +
Sbjct: 451 -----SQKVHSFFQSISSDSLHSINNLQSS--------LKTSKILEHLKEDSSEASSQEE 497
Query: 186 KVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTY-QRTLLGFWKKTARMMSQ 244
V K K + V+ +G S C+ L Y ++ + W+K + Q
Sbjct: 498 DVLQHAIIHKKHTGKSPI-----VNNIGTS-CSPLDGLTMQYSEQNGIVDWRKQSCTTIQ 551
Query: 245 IHEACI---GFHPYDFVALKQLQDTPSK-ISEDNKDEQIGGFLTEQLNKLVLSDEEASFE 300
E C+ H + +L + K +E K ++ L ++N + LS + +
Sbjct: 552 HPEHCVTSADQHSAEKRSLSSINKKKGKPQTEKEKIKKTDNRLNSRINGIRLSTPQHAHG 611
Query: 301 S--EQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGS 358
+ N D H E + +S+ + D +S E E+ EK+ +N SG+
Sbjct: 612 GTVKDVNLDIGSGHDTCGETSSESYSSPSSPRHD-GRESFESEE-EKDRDTDSNSEDSGN 669
Query: 359 SSTSEFTQECQTAFGSPSASLTSQEP----SMGSE 389
ST+ F T +GS + ++T + P S+G+E
Sbjct: 670 PSTTRF-----TGYGSVNQTVTVKPPVQIASLGNE 699
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 32.7 bits (73), Expect = 0.75
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 11/112 (9%)
Query: 348 SFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGSEPLAHSSRFLPSQLFDLGF 407
S L + L SS S+ Q+C ++ P SEP H+S + D
Sbjct: 378 SMLKDDLKLSSSEDSDGEQDCDK-------TMPRSTPGSNSEPSHHNSEGADNSRDDSSS 430
Query: 408 HVAGAFNNWVSQEESELCLSHTD-NQPVPSQSPKKLTRSPNNGNQDMSAWFN 458
H +G+ ++ S ESE S ++ N+P S SP+ P + W N
Sbjct: 431 H-SGSESSSGSDSESESSSSDSEANEPSQSASPE--PEPPPTNKWQLDNWLN 479
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 32.3 bits (72), Expect = 0.98
Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 10/118 (8%)
Query: 287 LNKLVLSDEEASFESEQANKDHNEKHSQMREFGAPQFSNSENVAK--DLPVDSLEGEDFE 344
LN+++ S E+S + + +K HN S FG+ + NV+K + + G
Sbjct: 998 LNQILSSSVESSNKGKVQSKLHNTVSSLAATFGS-KLGQQINVSKKGTIYIGKRRG---R 1053
Query: 345 KEFSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGSEPLAHSSRFLPSQL 402
K + LN +LS +S + Q Q A GS + P + S A SS LPS +
Sbjct: 1054 KPKTVLNGILSGSPTSLAVLEQTAQQAAGSALGQIL--PPLLPSS--ASSSEILPSPI 1107
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 32.3 bits (72), Expect = 0.98
Identities = 70/368 (19%), Positives = 131/368 (35%), Gaps = 40/368 (10%)
Query: 31 IKATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIEKYQLRLNVISEEENELGLF 90
+K +KE L +L + E + ++ + +E L EE+ L
Sbjct: 1216 VKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLIND 1275
Query: 91 LKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTIN 150
L Q R T+AG+ ++ AL + LSR KQ A + + +
Sbjct: 1276 LTAQRARLQTEAGE--------YSRQLDEKDALVSQLSRSKQ--------ASTQQIEELK 1319
Query: 151 RMEQARTEYRGALLWMKDVSQELDPDTLKQM---EKFRKVQMQVRNSKASFDKLKMDVCQ 207
+ T+ + AL S+ D D L++ E+ K ++Q SKA+ + +
Sbjct: 1320 HQLEEETKAKNALAHALQSSRH-DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378
Query: 208 KVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHEACIGFHPYDFVALKQLQDTP 267
+ D + + L ++ L ++ + ++ C +++D
Sbjct: 1379 ETDAI------QRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1432
Query: 268 SKISEDNKDEQIGGFLTEQLN-KLVLSDEEASFESEQANKDHNEKHSQMREFGAPQFSN- 325
+ N +Q N VLS+ + +E QA + ++K S+ + N
Sbjct: 1433 LDVERSN--AACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNV 1490
Query: 326 SENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSSTSEFTQ----------ECQTAFGSP 375
E L E ++ ++E S L ++ G E + E Q A
Sbjct: 1491 YEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEA 1550
Query: 376 SASLTSQE 383
ASL +E
Sbjct: 1551 EASLEHEE 1558
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 32.0 bits (71), Expect = 1.3
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 11/163 (6%)
Query: 166 MKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLT 225
+KD + L M+K R+ Q Q+ ++ LKM V + M +
Sbjct: 188 IKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYS 247
Query: 226 TYQRTLLGFWKKTARMMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGF--L 283
Y+ L +K + + E F A K++Q ++IS + KD++IG L
Sbjct: 248 QYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQ--AAEISLEEKDQRIGELDRL 305
Query: 284 TEQLNK------LVLSDEEASFESEQANKDHNEKHSQMREFGA 320
E++ K L L + E E + D E++ Q+ E A
Sbjct: 306 IERMEKERHQLQLQLLEHETEMSGELTDSD-KERYQQLEEASA 347
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 32.0 bits (71), Expect = 1.3
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 11/163 (6%)
Query: 166 MKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLT 225
+KD + L M+K R+ Q Q+ ++ LKM V + M +
Sbjct: 188 IKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYS 247
Query: 226 TYQRTLLGFWKKTARMMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGF--L 283
Y+ L +K + + E F A K++Q ++IS + KD++IG L
Sbjct: 248 QYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQ--AAEISLEEKDQRIGELDRL 305
Query: 284 TEQLNK------LVLSDEEASFESEQANKDHNEKHSQMREFGA 320
E++ K L L + E E + D E++ Q+ E A
Sbjct: 306 IERMEKERHQLQLQLLEHETEMSGELTDSD-KERYQQLEEASA 347
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,732,762
Number of Sequences: 37866
Number of extensions: 780000
Number of successful extensions: 2690
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 2643
Number of HSP's gapped (non-prelim): 114
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.