Search of human proteins with 22035609

Search of human proteins with 22035609

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
         (811 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...  1649   0.0  
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...  1649   0.0  
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...  1383   0.0  
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...   724   0.0  
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...   724   0.0  
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...   221   2e-57
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...   221   2e-57
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...   221   2e-57
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...   221   2e-57
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...   221   2e-57
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap...   221   2e-57
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap...   221   2e-57
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]          218   2e-56
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...   217   3e-56
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   139   1e-32
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   139   1e-32
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   134   3e-31
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   134   3e-31
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...   115   1e-25
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...   115   1e-25
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...   106   8e-23
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...   106   8e-23
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...   106   8e-23
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...   106   8e-23
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]      103   6e-22
gi|4505531 oxysterol binding protein [Homo sapiens]                   102   1e-21
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]    96   1e-19
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    37   0.056
gi|4557719 DNA ligase I [Homo sapiens]                                 37   0.073
gi|164419758 bromodomain containing 2 [Homo sapiens]                   36   0.16 

>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score = 1649 bits (4269), Expect = 0.0
 Identities = 811/811 (100%), Positives = 811/811 (100%)

Query: 1   MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE 60
           MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
Sbjct: 1   MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE 60

Query: 61  GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA 120
           GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
Sbjct: 61  GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA 120

Query: 121 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL 180
           LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL
Sbjct: 121 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL 180

Query: 181 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN 240
           RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN
Sbjct: 181 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN 240

Query: 241 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK 300
           PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK
Sbjct: 241 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK 300

Query: 301 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL 360
           SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL
Sbjct: 301 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL 360

Query: 361 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS 420
           VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS
Sbjct: 361 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS 420

Query: 421 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT 480
           NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT
Sbjct: 421 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT 480

Query: 481 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF 540
           LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF
Sbjct: 481 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF 540

Query: 541 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ 600
           IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ
Sbjct: 541 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ 600

Query: 601 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG 660
           EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG
Sbjct: 601 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG 660

Query: 661 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL 720
           ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL
Sbjct: 661 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL 720

Query: 721 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ 780
           SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ
Sbjct: 721 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ 780

Query: 781 APTPGLLQSPRSWFLLCVFLACQLFINHILK 811
           APTPGLLQSPRSWFLLCVFLACQLFINHILK
Sbjct: 781 APTPGLLQSPRSWFLLCVFLACQLFINHILK 811


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score = 1649 bits (4269), Expect = 0.0
 Identities = 811/811 (100%), Positives = 811/811 (100%)

Query: 1   MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE 60
           MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
Sbjct: 1   MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE 60

Query: 61  GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA 120
           GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
Sbjct: 61  GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA 120

Query: 121 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL 180
           LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL
Sbjct: 121 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL 180

Query: 181 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN 240
           RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN
Sbjct: 181 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN 240

Query: 241 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK 300
           PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK
Sbjct: 241 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK 300

Query: 301 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL 360
           SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL
Sbjct: 301 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL 360

Query: 361 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS 420
           VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS
Sbjct: 361 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS 420

Query: 421 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT 480
           NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT
Sbjct: 421 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT 480

Query: 481 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF 540
           LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF
Sbjct: 481 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF 540

Query: 541 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ 600
           IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ
Sbjct: 541 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ 600

Query: 601 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG 660
           EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG
Sbjct: 601 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG 660

Query: 661 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL 720
           ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL
Sbjct: 661 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL 720

Query: 721 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ 780
           SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ
Sbjct: 721 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ 780

Query: 781 APTPGLLQSPRSWFLLCVFLACQLFINHILK 811
           APTPGLLQSPRSWFLLCVFLACQLFINHILK
Sbjct: 781 APTPGLLQSPRSWFLLCVFLACQLFINHILK 811


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score = 1383 bits (3580), Expect = 0.0
 Identities = 678/680 (99%), Positives = 680/680 (100%)

Query: 132 SLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDG 191
           ++KGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDG
Sbjct: 200 AVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDG 259

Query: 192 EPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDH 251
           EPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDH
Sbjct: 260 EPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDH 319

Query: 252 SRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLR 311
           SRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLR
Sbjct: 320 SRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLR 379

Query: 312 PGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYK 371
           PGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYK
Sbjct: 380 PGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYK 439

Query: 372 KPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGS 431
           KPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGS
Sbjct: 440 KPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGS 499

Query: 432 ITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIEC 491
           ITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIEC
Sbjct: 500 ITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIEC 559

Query: 492 AKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSAL 551
           AKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSAL
Sbjct: 560 AKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSAL 619

Query: 552 FWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQ 611
           FWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQ
Sbjct: 620 FWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQ 679

Query: 612 RARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVA 671
           RARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVA
Sbjct: 680 RARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVA 739

Query: 672 RQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVP 731
           RQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVP
Sbjct: 740 RQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVP 799

Query: 732 GGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPR 791
           GGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPR
Sbjct: 800 GGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPR 859

Query: 792 SWFLLCVFLACQLFINHILK 811
           SWFLLCVFLACQLFINHILK
Sbjct: 860 SWFLLCVFLACQLFINHILK 879



 Score =  272 bits (696), Expect = 8e-73
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE 60
           MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
Sbjct: 1   MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE 60

Query: 61  GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA 120
           GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
Sbjct: 61  GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA 120

Query: 121 LTDPSVVIMADSLK 134
           LTDPSVVIMADSLK
Sbjct: 121 LTDPSVVIMADSLK 134


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score =  724 bits (1870), Expect = 0.0
 Identities = 373/696 (53%), Positives = 484/696 (69%), Gaps = 44/696 (6%)

Query: 132 SLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDG 191
           ++KGPKGE+VGSITQPLPSSYLI RA SESDGRCW+DALELAL+CSSLL+    + G++ 
Sbjct: 180 AVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEH 239

Query: 192 EPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN------DAFSDKSERENPEESD 245
           +   S D++  +  GL  +  +H   D F LN S +E       D +SDKS++EN +E D
Sbjct: 240 DLSVSSDSTHVTFYGLLRANNLHSG-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHD 298

Query: 246 -TETQDHSRKTESGSDQSET---------PGAPVRRGTTYVEQVQEELGELGEASQVETV 295
            ++ +   +  ES +D SE          P  P++  TTY EQ  EELGE GEASQ ETV
Sbjct: 299 ESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETV 357

Query: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
           SEENKSL+WTLLKQ+RPGMDLS+VVLPTF+LEPRSFL+KLSDYYYHAD LS AA+EE+ Y
Sbjct: 358 SEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPY 417

Query: 356 SRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVS 415
            R+K V++WYLSGFYKKPKG+KKPYNPILGETFRC W HP+T+S+TFYIAEQVSHHPP+S
Sbjct: 418 FRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPIS 477

Query: 416 AFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGIL 475
           AF+VSNRKDGFC+SGSI AKS+FYGNSLSA+L+G+A LTFLNR EDY +TMPYAHCKGIL
Sbjct: 478 AFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGIL 537

Query: 476 YGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHW 535
           YGTMTLELGG V I C K  + A LEFKLKPF G S  +NQISGK+  G+EVLA+L GHW
Sbjct: 538 YGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHW 597

Query: 536 DRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQ 595
           D +VFI ++ + +S +FW P+ ++++ RL +HTV  EEQ + ESE+LWQ VTRAI+  DQ
Sbjct: 598 DSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQ 657

Query: 596 HRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQ 655
             ATQEK+ LEEAQRQ AR+R+     W  +LF LDP+T EWHY++ D  PWDPL D+ Q
Sbjct: 658 TEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQ 717

Query: 656 FEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPE 715
           FE+DG+++T     V  +T  +  P  +H+ +   +++ K    P    Q  +SSGS  +
Sbjct: 718 FEKDGVIQT----KVKHRTPMVSVPKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQ 771

Query: 716 SCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSST 775
           S                   P  R RK+   L  +  +I SI++ Q+E+ R++ A+ +  
Sbjct: 772 SV-----------------KPSTR-RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHL 813

Query: 776 ARAAQAPTPGLLQSPRSWFLLCVFLACQLFINHILK 811
              +  P        + +F++ + +  Q+ IN + K
Sbjct: 814 --VSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK 847


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score =  724 bits (1870), Expect = 0.0
 Identities = 373/696 (53%), Positives = 484/696 (69%), Gaps = 44/696 (6%)

Query: 132 SLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDG 191
           ++KGPKGE+VGSITQPLPSSYLI RA SESDGRCW+DALELAL+CSSLL+    + G++ 
Sbjct: 222 AVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEH 281

Query: 192 EPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN------DAFSDKSERENPEESD 245
           +   S D++  +  GL  +  +H   D F LN S +E       D +SDKS++EN +E D
Sbjct: 282 DLSVSSDSTHVTFYGLLRANNLHSG-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHD 340

Query: 246 -TETQDHSRKTESGSDQSET---------PGAPVRRGTTYVEQVQEELGELGEASQVETV 295
            ++ +   +  ES +D SE          P  P++  TTY EQ  EELGE GEASQ ETV
Sbjct: 341 ESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETV 399

Query: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
           SEENKSL+WTLLKQ+RPGMDLS+VVLPTF+LEPRSFL+KLSDYYYHAD LS AA+EE+ Y
Sbjct: 400 SEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPY 459

Query: 356 SRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVS 415
            R+K V++WYLSGFYKKPKG+KKPYNPILGETFRC W HP+T+S+TFYIAEQVSHHPP+S
Sbjct: 460 FRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPIS 519

Query: 416 AFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGIL 475
           AF+VSNRKDGFC+SGSI AKS+FYGNSLSA+L+G+A LTFLNR EDY +TMPYAHCKGIL
Sbjct: 520 AFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGIL 579

Query: 476 YGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHW 535
           YGTMTLELGG V I C K  + A LEFKLKPF G S  +NQISGK+  G+EVLA+L GHW
Sbjct: 580 YGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHW 639

Query: 536 DRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQ 595
           D +VFI ++ + +S +FW P+ ++++ RL +HTV  EEQ + ESE+LWQ VTRAI+  DQ
Sbjct: 640 DSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQ 699

Query: 596 HRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQ 655
             ATQEK+ LEEAQRQ AR+R+     W  +LF LDP+T EWHY++ D  PWDPL D+ Q
Sbjct: 700 TEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQ 759

Query: 656 FEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPE 715
           FE+DG+++T     V  +T  +  P  +H+ +   +++ K    P    Q  +SSGS  +
Sbjct: 760 FEKDGVIQT----KVKHRTPMVSVPKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQ 813

Query: 716 SCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSST 775
           S                   P  R RK+   L  +  +I SI++ Q+E+ R++ A+ +  
Sbjct: 814 SV-----------------KPSTR-RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHL 855

Query: 776 ARAAQAPTPGLLQSPRSWFLLCVFLACQLFINHILK 811
              +  P        + +F++ + +  Q+ IN + K
Sbjct: 856 --VSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK 889


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score =  221 bits (563), Expect = 2e-57
 Identities = 158/470 (33%), Positives = 234/470 (49%), Gaps = 47/470 (10%)

Query: 196 SPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRK- 254
           S  + PSS    P+   + P+    P    S   D F D  E      S     D S   
Sbjct: 261 SGHSPPSSSLTSPSHVNLSPNT--VPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSA 318

Query: 255 ---TESGS-------DQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSL 302
              T S S       D +E+  + +  GT+  +     ++  +  EA  VE    E+KS+
Sbjct: 319 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSV 374

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +  LL Q+R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V+
Sbjct: 375 IMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVV 434

Query: 363 RWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FY 403
           +WYLS F+   KG   KKPYNPILGE F+C W  P  T+  T                 +
Sbjct: 435 KWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 494

Query: 404 IAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYT 463
           +AEQVSHHPP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y 
Sbjct: 495 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 554

Query: 464 LTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS 523
           LT P  + + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S
Sbjct: 555 LTFPNGYGRSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFS 611

Query: 524 --GEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESER 581
              ++   S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  
Sbjct: 612 PNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRS 667

Query: 582 LWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
           LW+ VT  +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 668 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 717


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score =  221 bits (563), Expect = 2e-57
 Identities = 158/470 (33%), Positives = 234/470 (49%), Gaps = 47/470 (10%)

Query: 196 SPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRK- 254
           S  + PSS    P+   + P+    P    S   D F D  E      S     D S   
Sbjct: 271 SGHSPPSSSLTSPSHVNLSPNT--VPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSA 328

Query: 255 ---TESGS-------DQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSL 302
              T S S       D +E+  + +  GT+  +     ++  +  EA  VE    E+KS+
Sbjct: 329 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSV 384

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +  LL Q+R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V+
Sbjct: 385 IMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVV 444

Query: 363 RWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FY 403
           +WYLS F+   KG   KKPYNPILGE F+C W  P  T+  T                 +
Sbjct: 445 KWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 504

Query: 404 IAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYT 463
           +AEQVSHHPP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y 
Sbjct: 505 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 564

Query: 464 LTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS 523
           LT P  + + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S
Sbjct: 565 LTFPNGYGRSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFS 621

Query: 524 --GEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESER 581
              ++   S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  
Sbjct: 622 PNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRS 677

Query: 582 LWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
           LW+ VT  +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 678 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 727


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score =  221 bits (563), Expect = 2e-57
 Identities = 158/470 (33%), Positives = 234/470 (49%), Gaps = 47/470 (10%)

Query: 196 SPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRK- 254
           S  + PSS    P+   + P+    P    S   D F D  E      S     D S   
Sbjct: 248 SGHSPPSSSLTSPSHVNLSPNT--VPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSA 305

Query: 255 ---TESGS-------DQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSL 302
              T S S       D +E+  + +  GT+  +     ++  +  EA  VE    E+KS+
Sbjct: 306 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSV 361

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +  LL Q+R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V+
Sbjct: 362 IMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVV 421

Query: 363 RWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FY 403
           +WYLS F+   KG   KKPYNPILGE F+C W  P  T+  T                 +
Sbjct: 422 KWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 481

Query: 404 IAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYT 463
           +AEQVSHHPP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y 
Sbjct: 482 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 541

Query: 464 LTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS 523
           LT P  + + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S
Sbjct: 542 LTFPNGYGRSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFS 598

Query: 524 --GEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESER 581
              ++   S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  
Sbjct: 599 PNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRS 654

Query: 582 LWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
           LW+ VT  +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 655 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 704


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score =  221 bits (563), Expect = 2e-57
 Identities = 158/470 (33%), Positives = 234/470 (49%), Gaps = 47/470 (10%)

Query: 196 SPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRK- 254
           S  + PSS    P+   + P+    P    S   D F D  E      S     D S   
Sbjct: 151 SGHSPPSSSLTSPSHVNLSPNT--VPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSA 208

Query: 255 ---TESGS-------DQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSL 302
              T S S       D +E+  + +  GT+  +     ++  +  EA  VE    E+KS+
Sbjct: 209 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSV 264

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +  LL Q+R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V+
Sbjct: 265 IMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVV 324

Query: 363 RWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FY 403
           +WYLS F+   KG   KKPYNPILGE F+C W  P  T+  T                 +
Sbjct: 325 KWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 384

Query: 404 IAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYT 463
           +AEQVSHHPP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y 
Sbjct: 385 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 444

Query: 464 LTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS 523
           LT P  + + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S
Sbjct: 445 LTFPNGYGRSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFS 501

Query: 524 --GEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESER 581
              ++   S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  
Sbjct: 502 PNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRS 557

Query: 582 LWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
           LW+ VT  +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 558 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 607


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score =  221 bits (563), Expect = 2e-57
 Identities = 158/470 (33%), Positives = 234/470 (49%), Gaps = 47/470 (10%)

Query: 196 SPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRK- 254
           S  + PSS    P+   + P+    P    S   D F D  E      S     D S   
Sbjct: 96  SGHSPPSSSLTSPSHVNLSPNT--VPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSA 153

Query: 255 ---TESGS-------DQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSL 302
              T S S       D +E+  + +  GT+  +     ++  +  EA  VE    E+KS+
Sbjct: 154 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSV 209

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +  LL Q+R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V+
Sbjct: 210 IMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVV 269

Query: 363 RWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FY 403
           +WYLS F+   KG   KKPYNPILGE F+C W  P  T+  T                 +
Sbjct: 270 KWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 329

Query: 404 IAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYT 463
           +AEQVSHHPP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y 
Sbjct: 330 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 389

Query: 464 LTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS 523
           LT P  + + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S
Sbjct: 390 LTFPNGYGRSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFS 446

Query: 524 --GEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESER 581
              ++   S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  
Sbjct: 447 PNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRS 502

Query: 582 LWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
           LW+ VT  +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 503 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 552


>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score =  221 bits (563), Expect = 2e-57
 Identities = 158/470 (33%), Positives = 234/470 (49%), Gaps = 47/470 (10%)

Query: 196 SPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRK- 254
           S  + PSS    P+   + P+    P    S   D F D  E      S     D S   
Sbjct: 83  SGHSPPSSSLTSPSHVNLSPNT--VPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSA 140

Query: 255 ---TESGS-------DQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSL 302
              T S S       D +E+  + +  GT+  +     ++  +  EA  VE    E+KS+
Sbjct: 141 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSV 196

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +  LL Q+R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V+
Sbjct: 197 IMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVV 256

Query: 363 RWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FY 403
           +WYLS F+   KG   KKPYNPILGE F+C W  P  T+  T                 +
Sbjct: 257 KWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 316

Query: 404 IAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYT 463
           +AEQVSHHPP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y 
Sbjct: 317 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 376

Query: 464 LTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS 523
           LT P  + + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S
Sbjct: 377 LTFPNGYGRSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFS 433

Query: 524 --GEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESER 581
              ++   S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  
Sbjct: 434 PNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRS 489

Query: 582 LWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
           LW+ VT  +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 490 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 539


>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score =  221 bits (563), Expect = 2e-57
 Identities = 158/470 (33%), Positives = 234/470 (49%), Gaps = 47/470 (10%)

Query: 196 SPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRK- 254
           S  + PSS    P+   + P+    P    S   D F D  E      S     D S   
Sbjct: 83  SGHSPPSSSLTSPSHVNLSPNT--VPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSA 140

Query: 255 ---TESGS-------DQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSL 302
              T S S       D +E+  + +  GT+  +     ++  +  EA  VE    E+KS+
Sbjct: 141 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSV 196

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +  LL Q+R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V+
Sbjct: 197 IMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVV 256

Query: 363 RWYLSGFYKKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FY 403
           +WYLS F+   KG   KKPYNPILGE F+C W  P  T+  T                 +
Sbjct: 257 KWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 316

Query: 404 IAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYT 463
           +AEQVSHHPP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y 
Sbjct: 317 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 376

Query: 464 LTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS 523
           LT P  + + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S
Sbjct: 377 LTFPNGYGRSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFS 433

Query: 524 --GEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESER 581
              ++   S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  
Sbjct: 434 PNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRS 489

Query: 582 LWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
           LW+ VT  +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 490 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 539


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score =  218 bits (554), Expect = 2e-56
 Identities = 137/414 (33%), Positives = 203/414 (49%), Gaps = 50/414 (12%)

Query: 259 SDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVS----------EENKSLMWTLLK 308
           +DQS+    P  +       +  E  E+    ++E             EE +S++  LL 
Sbjct: 316 TDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLS 375

Query: 309 QLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSG 368
           QL+ GMDL+RVVLPTF+LE RS L   +D+  H DL         A  RM   + +YL+ 
Sbjct: 376 QLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTS 435

Query: 369 FYKKPKGI--KKPYNPILGETFRCCWFHPQTD--SRTF---------------------- 402
           F++  KG   KKPYNPI+GETF C W  P+++  S  F                      
Sbjct: 436 FHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQV 495

Query: 403 --------YIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLT 454
                   ++AEQVSHHPPVS F+    +   C++  +  KS+F G S+   + G+  L+
Sbjct: 496 GSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILS 555

Query: 455 FLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSI 514
            L   E+YT ++P A+ + IL     +ELGGKV++ CAK  + A + F  KPF+GG    
Sbjct: 556 LLEHGEEYTFSLPCAYARSIL-TVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHR 614

Query: 515 NQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQ 574
                K      V+  + G W+  V      +G +         V ++R+R    PLE+Q
Sbjct: 615 VTAEVKHNITNTVVCRVQGEWN-SVLEFTYSNGETKYVDLTKLAVTKKRVR----PLEKQ 669

Query: 575 TELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
              ES RLW++VT ++ + +  +AT+ K  LEE QR   R R E+  PWK + F
Sbjct: 670 DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score =  217 bits (553), Expect = 3e-56
 Identities = 133/397 (33%), Positives = 200/397 (50%), Gaps = 34/397 (8%)

Query: 260 DQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRV 319
           +Q+  P      G+  V    E+     +      V E+ +S++  L+ QL+ GMDL++V
Sbjct: 357 EQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQLKLGMDLTKV 416

Query: 320 VLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGI--K 377
           VLPTF+LE RS L   +D+  H DLL           R+   + +YL+ F++  KG   K
Sbjct: 417 VLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAK 476

Query: 378 KPYNPILGETFRCCWF---------------------HPQTD--SRTF---YIAEQVSHH 411
           KPYNPI+GETF C W                      HP  D  S+++   ++AEQVSHH
Sbjct: 477 KPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHH 536

Query: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
           PP+S F+    +   C++  +  KS+F G S+   + G+  L  L   E+Y  T+P A+ 
Sbjct: 537 PPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYA 596

Query: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASL 531
           + IL     +ELGGKV+I CAK  + A + F  KPF+GG         K      ++   
Sbjct: 597 RSIL-TIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKA 655

Query: 532 SGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAIS 591
            G W+  +      +G + +  T +  V  +++R    PLE+Q  +ES  LW+ VTR + 
Sbjct: 656 HGEWNGTLEF-TYNNGETKVIDTTTLPVYPKKIR----PLEKQGPMESRNLWREVTRYLR 710

Query: 592 KGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
            GD   AT++K  LEE QR   R+R+    PWKP+ F
Sbjct: 711 LGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYF 747


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  139 bits (349), Expect = 1e-32
 Identities = 117/407 (28%), Positives = 175/407 (42%), Gaps = 68/407 (16%)

Query: 299 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM 358
           N   +W++L++   GM+LS++ +P    EP SFL +L++Y  H  L+ +A+   D   RM
Sbjct: 32  NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 90

Query: 359 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH 418
           + V  + +S    + +   KP+NP+LGET+       + D     I+EQVSHHPP+SAFH
Sbjct: 91  QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 146

Query: 419 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT 478
                + F   GSI  K +F+G S+ A   G  TL  L   E YT T P      I+ G 
Sbjct: 147 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 206

Query: 479 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR 537
           + +E  G V I   K   +  L FK    FG    ++++ G I    ++ L +L G W  
Sbjct: 207 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFG--KELHKVEGYIQDKSKKKLCALYGKWTE 264

Query: 538 ----------DVFIKEEGSGS-------------------------------SALFW--- 553
                     D + K +   +                               S L W   
Sbjct: 265 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 324

Query: 554 -TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFAL 605
             P    +        + L E   ++ES       RL   + RA+  G+  +A++EK  L
Sbjct: 325 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDI-RAMENGEIDQASEEKKRL 383

Query: 606 EEAQRQRARERQESLMPWKPQLFHLDPI----TQEWHYRYEDHSPWD 648
           EE QR   + R +S   WK + FH  P      Q+W Y     S WD
Sbjct: 384 EEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY---SGSYWD 427


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  139 bits (349), Expect = 1e-32
 Identities = 117/407 (28%), Positives = 175/407 (42%), Gaps = 68/407 (16%)

Query: 299 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM 358
           N   +W++L++   GM+LS++ +P    EP SFL +L++Y  H  L+ +A+   D   RM
Sbjct: 545 NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 603

Query: 359 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH 418
           + V  + +S    + +   KP+NP+LGET+       + D     I+EQVSHHPP+SAFH
Sbjct: 604 QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 659

Query: 419 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT 478
                + F   GSI  K +F+G S+ A   G  TL  L   E YT T P      I+ G 
Sbjct: 660 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 719

Query: 479 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR 537
           + +E  G V I   K   +  L FK    FG    ++++ G I    ++ L +L G W  
Sbjct: 720 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFG--KELHKVEGYIQDKSKKKLCALYGKWTE 777

Query: 538 ----------DVFIKEEGSGS-------------------------------SALFW--- 553
                     D + K +   +                               S L W   
Sbjct: 778 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 837

Query: 554 -TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFAL 605
             P    +        + L E   ++ES       RL   + RA+  G+  +A++EK  L
Sbjct: 838 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDI-RAMENGEIDQASEEKKRL 896

Query: 606 EEAQRQRARERQESLMPWKPQLFHLDPI----TQEWHYRYEDHSPWD 648
           EE QR   + R +S   WK + FH  P      Q+W Y     S WD
Sbjct: 897 EEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY---SGSYWD 940


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  134 bits (337), Expect = 3e-31
 Identities = 109/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +WT+LK+   G++LS++ +P    EP SFL ++++Y  H  L+ RA+ +     RM+ V 
Sbjct: 76  VWTILKKC-VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVA 134

Query: 363 RWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNR 422
            + +S    + +   KP+NP+LGET+       + D    +I+EQVSHHPP+SAFH    
Sbjct: 135 AFAVSAVASQWERTGKPFNPLLGETYELI----REDLGFRFISEQVSHHPPISAFHSEGL 190

Query: 423 KDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLE 482
              F   GSI  K +F+G S+ A   G  TL  L   E YT T P      ++ G + +E
Sbjct: 191 NHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIE 250

Query: 483 LGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR---- 537
             G V I   +   +  L FK    FG    ++++ G I    ++ L  + G W      
Sbjct: 251 QYGTVEILNHRTGHKCVLHFKPCGLFG--KELHKVEGHIQDKNKKKLFMIYGKWTECLWG 308

Query: 538 ------DVFIKEEGSG----------------------------------SSALFW---- 553
                 + F K+E  G                                   S L W    
Sbjct: 309 IDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINT 368

Query: 554 TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFALE 606
            P    +       TV L E +T +E        RL   + R +  G+   A+QEK  LE
Sbjct: 369 RPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDI-RGMENGNMDLASQEKERLE 427

Query: 607 EAQRQRARERQESLMPWKPQLFH 629
           E QR+  RER +    W+ + F+
Sbjct: 428 EKQREARRERAKEEAEWQTRWFY 450


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  134 bits (337), Expect = 3e-31
 Identities = 109/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +WT+LK+   G++LS++ +P    EP SFL ++++Y  H  L+ RA+ +     RM+ V 
Sbjct: 64  VWTILKKC-VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVA 122

Query: 363 RWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNR 422
            + +S    + +   KP+NP+LGET+       + D    +I+EQVSHHPP+SAFH    
Sbjct: 123 AFAVSAVASQWERTGKPFNPLLGETYELI----REDLGFRFISEQVSHHPPISAFHSEGL 178

Query: 423 KDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLE 482
              F   GSI  K +F+G S+ A   G  TL  L   E YT T P      ++ G + +E
Sbjct: 179 NHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIE 238

Query: 483 LGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR---- 537
             G V I   +   +  L FK    FG    ++++ G I    ++ L  + G W      
Sbjct: 239 QYGTVEILNHRTGHKCVLHFKPCGLFG--KELHKVEGHIQDKNKKKLFMIYGKWTECLWG 296

Query: 538 ------DVFIKEEGSG----------------------------------SSALFW---- 553
                 + F K+E  G                                   S L W    
Sbjct: 297 IDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINT 356

Query: 554 TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFALE 606
            P    +       TV L E +T +E        RL   + R +  G+   A+QEK  LE
Sbjct: 357 RPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDI-RGMENGNMDLASQEKERLE 415

Query: 607 EAQRQRARERQESLMPWKPQLFH 629
           E QR+  RER +    W+ + F+
Sbjct: 416 EKQREARRERAKEEAEWQTRWFY 438


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 222 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 276
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 507 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 559

Query: 277 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 336
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 560 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 607

Query: 337 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 395
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 608 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 663

Query: 396 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 455
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 664 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 721

Query: 456 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 514
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 722 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 779

Query: 515 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 569
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 780 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 837

Query: 570 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 623
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 838 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 897

Query: 624 KPQLF 628
            P+ F
Sbjct: 898 IPKFF 902


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 222 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 276
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 503 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 555

Query: 277 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 336
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 556 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 603

Query: 337 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 395
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 604 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 659

Query: 396 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 455
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 660 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 717

Query: 456 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 514
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 718 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 775

Query: 515 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 569
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 776 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 833

Query: 570 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 623
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 834 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 893

Query: 624 KPQLF 628
            P+ F
Sbjct: 894 IPKFF 898


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 455 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 512

Query: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 513 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 565

Query: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 566 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 623

Query: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 624 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 680

Query: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 681 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 738

Query: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 739 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 788


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 486 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 543

Query: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 544 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 596

Query: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 597 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 654

Query: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 655 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 711

Query: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 712 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 769

Query: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 770 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 819


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 491 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 548

Query: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 549 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 601

Query: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 602 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 659

Query: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 660 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 716

Query: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 717 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 774

Query: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 775 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 824


>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 522 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 579

Query: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 580 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 632

Query: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 633 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 690

Query: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 691 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 747

Query: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 748 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 805

Query: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 806 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 855


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score =  103 bits (257), Expect = 6e-22
 Identities = 107/409 (26%), Positives = 172/409 (42%), Gaps = 46/409 (11%)

Query: 246 TETQDHSRKTESGSDQSETPGAP---VRRGTTYVEQVQEELGELGEASQVETVSEENKSL 302
           TE ++ SRK E  +  S    +    V  G + V +     G      +V   ++ N SL
Sbjct: 467 TEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPK-----GSSKVKRRVRIPNKPNYSL 521

Query: 303 -MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLV 361
            +W+++K    G +LSR+ +P    EP S L +L++   +  LL +A     +  +M LV
Sbjct: 522 NLWSIMKNCI-GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLV 580

Query: 362 LRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSN 421
             + +S +      I KP+NP+LGETF         D     + EQVSHHPP SA H   
Sbjct: 581 AAFSVSSYSTTVHRIAKPFNPMLGETFE---LDRLDDMGLRSLCEQVSHHPP-SAAHYVF 636

Query: 422 RKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTL 481
            K G+ +   IT  S+F G  +S +  G   L F      Y      +    I+ G + +
Sbjct: 637 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI 696

Query: 482 ELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGE-EVLASLSGHWDRDVF 540
           +  G + I   K N + QL+F    +F    +  +++G ++  + +    LSG WD  + 
Sbjct: 697 DQSGDIEIVNHKTNDRCQLKFLPYSYF-SKEAARKVTGVVSDSQGKAHYVLSGSWDEQME 755

Query: 541 IKEEGSGSSALFWTPSGEVRRQRLRQ--------HTVPLEEQTE---------------- 576
             +    S +   +PS + +++ + Q           PL E  E                
Sbjct: 756 CSKVMHSSPS---SPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHE 812

Query: 577 ---LESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMP 622
                ++   +   R + KG    A  EK  LEE QR   R R E+  P
Sbjct: 813 EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGP 861


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  102 bits (255), Expect = 1e-21
 Identities = 97/392 (24%), Positives = 166/392 (42%), Gaps = 31/392 (7%)

Query: 277 EQVQEELGELGEASQVETVSEENKSL-MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKL 335
           EQ + +L E  +  +     + N SL +W+++K    G +LS++ +P    EP S L +L
Sbjct: 392 EQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCI-GKELSKIPMPVNFNEPLSMLQRL 450

Query: 336 SDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHP 395
           ++   + +LL RAA  E++  ++  V  + +S +        KP+NP+LGETF       
Sbjct: 451 TEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFE---LDR 507

Query: 396 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 455
             ++    + EQVSHHPP +A H  + K+G+ +   I   S+F G  LS +  G     F
Sbjct: 508 LEENGYRSLCEQVSHHPPAAAHHAES-KNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIF 566

Query: 456 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSIN 515
                 YT          I+ G + ++  G++ I   K   +  L+F    +F    +  
Sbjct: 567 HATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVA-R 625

Query: 516 QISGKITS-GEEVLASLSGHWDRDVF------IKEEGSGSSALFWTPSGEVRRQRLRQHT 568
           +++G++T    +V  +L G WD  +       +  E  G +      + E R    +++ 
Sbjct: 626 KVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNP 685

Query: 569 VPLEEQTELESERL------WQHVT-----------RAISKGDQHRATQEKFALEEAQRQ 611
           +P   +       L      W+  T           R +  G    A  EK  LEE QR 
Sbjct: 686 LPKNAENMYYFSELALTLNAWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRL 745

Query: 612 RARERQESLMPWKPQLFHLDPITQEWHYRYED 643
             ++R+   M         DP    W  R +D
Sbjct: 746 SRKKREAEAMKATEDGTPYDPYKALWFERKKD 777


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 86/350 (24%), Positives = 157/350 (44%), Gaps = 26/350 (7%)

Query: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
           +W +L+    G DLS+V +P  + EP + L +L +   ++ LL +A+   D   RM  + 
Sbjct: 479 LWNILRN-NIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIA 537

Query: 363 RWYLSGFYKK-PKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSN 421
            + +S +     +   KP+NP+LGET+ C     + D    +I+EQVSHHPP+SA H  +
Sbjct: 538 AFAVSAYSSTYHRAGCKPFNPVLGETYEC----ERPDRGFRFISEQVSHHPPISACHAES 593

Query: 422 RKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTL 481
             + F     +  K++F+G SL  +  G   ++     + +      +    +L G   +
Sbjct: 594 --ENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWI 651

Query: 482 ELGGKVTIECAK-NNFQAQLEFKLKPFFGGSTSINQISGKITS-GEEVLASLSGHWDRDV 539
           E  G+V I   + ++   ++ F    ++  S++++++ G + S    VL  L G W   +
Sbjct: 652 EHYGEVLIRNTQDSSCHCKITFCKAKYW--SSNVHEVQGAVLSRSGRVLHRLFGKWHEGL 709

Query: 540 FIKEEGSGSSALFWTPSG----EVRRQRLRQHTVPLEEQTELESERLWQHVTRA------ 589
           +      G     W P+       R     Q  + L E T      L    TR       
Sbjct: 710 YRGPTPGGQ--CIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLRPDQRY 767

Query: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF--HLDPITQEW 637
           + +G+   A  +K  +E+ QR R +  +E+ +  + + F    D   +EW
Sbjct: 768 LEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDSSGKEW 817


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 37.4 bits (85), Expect = 0.056
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 216 DQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTY 275
           ++DL  +N +S + +   ++ E E  EE + E +D   + E   D+ E           +
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEE---DEEEYFEEEEEEEEEF 931

Query: 276 VEQVQEELGELGEASQVETVSEENK 300
            E+ +EE GEL E  + E   EE +
Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEE 956


>gi|4557719 DNA ligase I [Homo sapiens]
          Length = 919

 Score = 37.0 bits (84), Expect = 0.073
 Identities = 51/212 (24%), Positives = 80/212 (37%), Gaps = 18/212 (8%)

Query: 103 KENYRQEKKRATRQLLSALTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESD 162
           K+  + +K        S  T+P          G   ES   + +P   +  +  +  E +
Sbjct: 12  KKEGKAKKPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRKAARVLGSEGEEE 71

Query: 163 GRCWLDAL--ELALRCSSLL--RLGTCKPGRDGEPGTSP-DASPSSLCGLPASATVHPD- 216
                 A   + AL CS +   R  T          TSP D+SPS   G+P   T     
Sbjct: 72  DEALSPAKGQKPALDCSQVSPPRPATSPENNASLSDTSPMDSSPS---GIPKRRTARKQL 128

Query: 217 -----QDLFPLNGSSLENDAFSDKSEREN--PEESDTETQDHSRKTESGSDQSETPGAPV 269
                Q++        + +A   K E E   P+ES TE +  + K     DQ  TP  P+
Sbjct: 129 PKRTIQEVLEEQSEDEDREAKRKKEEEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPL 188

Query: 270 RRGTTYVEQVQEELGELGEASQVETVSEENKS 301
           +  T+  E   E + E   A++ E   EE ++
Sbjct: 189 K--TSKAETPTESVSEPEVATKQELQEEEEQT 218


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 20/80 (25%), Positives = 37/80 (46%)

Query: 680 PGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPR 739
           PGP    +     L K+S + S    ++ESS    E   E  +EE++ +     E    R
Sbjct: 460 PGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHR 519

Query: 740 CRKEARRLQALHEAILSIRE 759
             +   +L+A+HE + ++ +
Sbjct: 520 LAELQEQLRAVHEQLAALSQ 539


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,357,008
Number of Sequences: 37866
Number of extensions: 1806477
Number of successful extensions: 8843
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 8351
Number of HSP's gapped (non-prelim): 655
length of query: 811
length of database: 18,247,518
effective HSP length: 111
effective length of query: 700
effective length of database: 14,044,392
effective search space: 9831074400
effective search space used: 9831074400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.