Search of human proteins with 22035554

Search of human proteins with 22035554

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035554 amyloid beta A4 precursor protein-binding, family
B, member 1 isoform delta E9 [Homo sapiens]
         (708 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035554 amyloid beta A4 precursor protein-binding, family B,...  1448   0.0  
gi|4502131 amyloid beta A4 precursor protein-binding, family B, ...  1443   0.0  
gi|50083291 amyloid beta A4 precursor protein-binding, family B,...   574   e-164
gi|95147542 amyloid beta precursor protein-binding, family B, me...   338   1e-92
gi|95147540 amyloid beta precursor protein-binding, family B, me...   333   4e-91
gi|95147536 amyloid beta precursor protein-binding, family B, me...   331   2e-90
gi|95147538 amyloid beta precursor protein-binding, family B, me...   330   3e-90
gi|210032580 SET domain containing 1B [Homo sapiens]                   52   2e-06
gi|55741677 SET domain containing 1A [Homo sapiens]                    50   7e-06
gi|209862789 microtubule associated monoxygenase, calponin and L...    49   2e-05
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]         45   2e-04
gi|46276863 parathymosin [Homo sapiens]                                44   4e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    44   7e-04
gi|189181750 human immunodeficiency virus type I enhancer bindin...    43   9e-04
gi|116089331 human immunodeficiency virus type I enhancer bindin...    43   9e-04
gi|239747212 PREDICTED: hypothetical protein XP_002346939 [Homo ...    43   0.001
gi|41349472 PR domain containing 16 isoform 2 [Homo sapiens]           43   0.001
gi|41349470 PR domain containing 16 isoform 1 [Homo sapiens]           43   0.001
gi|197313748 SET domain containing 2 [Homo sapiens]                    43   0.001
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    42   0.002
gi|164419758 bromodomain containing 2 [Homo sapiens]                   42   0.002
gi|4826806 bromodomain containing 2 [Homo sapiens]                     42   0.002
gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]       42   0.002
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    42   0.002
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    42   0.002
gi|17975763 myelin transcription factor 1 [Homo sapiens]               42   0.003
gi|10863935 reticulon 1 isoform A [Homo sapiens]                       42   0.003
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    41   0.003
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         41   0.003
gi|194688135 high-mobility group box 2 [Homo sapiens]                  41   0.004

>gi|22035554 amyloid beta A4 precursor protein-binding, family B,
           member 1 isoform delta E9 [Homo sapiens]
          Length = 708

 Score = 1448 bits (3749), Expect = 0.0
 Identities = 708/708 (100%), Positives = 708/708 (100%)

Query: 1   MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGP 60
           MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGP
Sbjct: 1   MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGP 60

Query: 61  EPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLIHLYSEL 120
           EPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLIHLYSEL
Sbjct: 61  EPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLIHLYSEL 120

Query: 121 ELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLP 180
           ELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLP
Sbjct: 121 ELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLP 180

Query: 181 EPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDT 240
           EPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDT
Sbjct: 181 EPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDT 240

Query: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300
           DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL
Sbjct: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300

Query: 301 TWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPP 360
           TWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPP
Sbjct: 301 TWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPP 360

Query: 361 RNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGK 420
           RNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGK
Sbjct: 361 RNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGK 420

Query: 421 DLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRDFAYVARDKLTQMLKCHVF 480
           DLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRDFAYVARDKLTQMLKCHVF
Sbjct: 421 DLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRDFAYVARDKLTQMLKCHVF 480

Query: 481 RCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQK 540
           RCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQK
Sbjct: 481 RCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQK 540

Query: 541 FQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLG 600
           FQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLG
Sbjct: 541 FQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLG 600

Query: 601 ECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCL 660
           ECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCL
Sbjct: 601 ECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCL 660

Query: 661 DARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGAHTP 708
           DARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGAHTP
Sbjct: 661 DARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGAHTP 708


>gi|4502131 amyloid beta A4 precursor protein-binding, family B,
           member 1 isoform E9 [Homo sapiens]
          Length = 710

 Score = 1443 bits (3736), Expect = 0.0
 Identities = 708/710 (99%), Positives = 708/710 (99%), Gaps = 2/710 (0%)

Query: 1   MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGP 60
           MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGP
Sbjct: 1   MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGP 60

Query: 61  EPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLIHLYSEL 120
           EPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLIHLYSEL
Sbjct: 61  EPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLIHLYSEL 120

Query: 121 ELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLP 180
           ELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLP
Sbjct: 121 ELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLP 180

Query: 181 EPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDT 240
           EPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDT
Sbjct: 181 EPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDT 240

Query: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300
           DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL
Sbjct: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300

Query: 301 TWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPP 360
           TWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPP
Sbjct: 301 TWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPP 360

Query: 361 RNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGK 420
           RNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGK
Sbjct: 361 RNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGK 420

Query: 421 DLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSG--RDFAYVARDKLTQMLKCH 478
           DLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSG  RDFAYVARDKLTQMLKCH
Sbjct: 421 DLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRERDFAYVARDKLTQMLKCH 480

Query: 479 VFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELV 538
           VFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELV
Sbjct: 481 VFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELV 540

Query: 539 QKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAV 598
           QKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAV
Sbjct: 541 QKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAV 600

Query: 599 LGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQK 658
           LGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQK
Sbjct: 601 LGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQK 660

Query: 659 CLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGAHTP 708
           CLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGAHTP
Sbjct: 661 CLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGAHTP 710


>gi|50083291 amyloid beta A4 precursor protein-binding, family B,
           member 2 [Homo sapiens]
          Length = 736

 Score =  574 bits (1480), Expect = e-164
 Identities = 344/737 (46%), Positives = 457/737 (62%), Gaps = 65/737 (8%)

Query: 5   SSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQAT----AVGPK--------DLRS 52
           SS +    N NS   P  +L L   ++HN+LLNA+++ T    +  PK        ++++
Sbjct: 20  SSGTTDVTNRNSPATPPNTLNL--RSSHNELLNAEIKHTETKNSTPPKCRKKYALTNIQA 77

Query: 53  AMG-EGGGPEP----GPANAKWLKEGQNQLRRAAT-AHRDQNRN------VTLTLAEEAS 100
           AMG      +P    G AN K +K G+NQLR+AA    +D N+N      + +T  +   
Sbjct: 78  AMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNKNLSPTAVINITSEKLEG 137

Query: 101 QEP--------EMAPLGP---KGLIHLYSELELSAHNAA-NRGLRGPGLIISTQEQGPDE 148
           +EP        E+ P  P   K  ++ Y++LE SA     NRG               +E
Sbjct: 138 KEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG---------NHHGTAEE 188

Query: 149 GEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASL 208
             +   G+A     + D   ++ +   P   PE  +       P+   D P+  +K+   
Sbjct: 189 KSQPVQGQASTIIGNGDLLLQKPN--RPQSSPEDGQVATVSSSPETKKDHPKTGAKTDCA 246

Query: 209 LFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGT 268
           L  ++N A SDE+SSW TLSQ S S  SP++TD  W+ ++F+TD DLP GW RV D +GT
Sbjct: 247 LHRIQNLAPSDEESSWTTLSQDSASPSSPDETD-IWSDHSFQTDPDLPPGWKRVSDIAGT 305

Query: 269 YYWHIPTGTTQWEPP-GRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPM 327
           YYWHIPTGTTQWE P    +  QGS     S +T +     E         D PS     
Sbjct: 306 YYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEDLHAATVNPD-PS----- 359

Query: 328 ELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPPRNTNPGIKCFAVRSLGWVEMTEEELAP 387
              LKE E  TL + +  L   P P +++     N++P  KCFAVRSLGWVEM EE+LAP
Sbjct: 360 ---LKEFEGATLRYASLKLRNAPHPDDDDSCSI-NSDPEAKCFAVRSLGWVEMAEEDLAP 415

Query: 388 GRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPQSQALLHAQPI 447
           G+SSVAVNNCIRQLSY KN++ D + G WGEGKD+ L LE++ L LV+P  +++LH+QPI
Sbjct: 416 GKSSVAVNNCIRQLSYCKNDIRDTV-GIWGEGKDMYLILENDMLSLVDPMDRSVLHSQPI 474

Query: 448 ISIRVWGVGRDSGRDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNA 507
           +SIRVWGVGRD+GRDFAYVARDK T++LKCHVFRC+ PAK IATSLHEICSKIMAER+NA
Sbjct: 475 VSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIATSLHEICSKIMAERKNA 534

Query: 508 RCLVNGLSLDHSKL-VDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALES 566
           + L      + + + +DVP Q +FP PK ELVQKF V YLG +PV KPVG+D++N A+E+
Sbjct: 535 KALACSSLQERANVNLDVPLQ-DFPTPKTELVQKFHVQYLGMLPVDKPVGMDILNSAIEN 593

Query: 567 VLSSSSREQWTPSHVSVAPATLTILHQQT-EAVLGECRVRFLSFLAVGRDVHTFAFIMAA 625
           +++SS++E W   +++VA AT+T++ ++  E VL ECRVRFLSF+ VG+DVHTFAFIM  
Sbjct: 594 LMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSFMGVGKDVHTFAFIMDT 653

Query: 626 GPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVARRVGW 685
           G   F CH+FWCEPNA ++SEAVQAACMLRYQKCL AR  +     P PPA+SV RRV  
Sbjct: 654 GNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKVRPPPPPADSVTRRVTT 713

Query: 686 TVRRGVQSLWGSLKPKR 702
            V+RGV SL  +LK KR
Sbjct: 714 NVKRGVLSLIDTLKQKR 730


>gi|95147542 amyloid beta precursor protein-binding, family B,
           member 3 isoform a [Homo sapiens]
          Length = 484

 Score =  338 bits (866), Expect = 1e-92
 Identities = 178/429 (41%), Positives = 253/429 (58%), Gaps = 37/429 (8%)

Query: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300
           D  W  ++ E ++ LP GW ++ D +GTYYWH+P+G+TQW+ P                 
Sbjct: 17  DDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRP----------------- 59

Query: 301 TWT-GFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLS-PEPLPQEEEKL 358
           TW  G A   G      W            GL+ P+  + +    SL     L     + 
Sbjct: 60  TWELGDAEDPGTGTEGIW------------GLRPPKGRSFSSLESSLDRSNSLSWYGGES 107

Query: 359 PPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGE 418
             ++  PG KCFAVRSLGWVE+ EE+LAPG+SS+AVNNCI+QL+  ++    P  G WGE
Sbjct: 108 YIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPP-DGAWGE 166

Query: 419 GKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRDFAYVARDKLTQMLKCH 478
           G+++L+ L+ + + LV P   +L+H QP++ IRVWGVG   GRDFA+VA DK + MLKCH
Sbjct: 167 GQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDFAFVASDKDSCMLKCH 226

Query: 479 VFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELV 538
           VF C+ PAK IA++LH +C++I++ER       +  S D     D+P QVE     ++  
Sbjct: 227 VFCCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAA 286

Query: 539 QKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEA- 597
           QK++  Y+G +PV K +G+DV+N A+ ++ +   R  W P+ +SV+ + +T    Q EA 
Sbjct: 287 QKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEAS 346

Query: 598 ----VLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACM 653
                L +C VR ++F+ VGRD HTF  I   G  SF C  FWC+P+A  LSEAVQAACM
Sbjct: 347 TEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACM 406

Query: 654 LRYQKCLDA 662
           ++YQKCL A
Sbjct: 407 VQYQKCLVA 415


>gi|95147540 amyloid beta precursor protein-binding, family B,
           member 3 isoform b [Homo sapiens]
          Length = 486

 Score =  333 bits (853), Expect = 4e-91
 Identities = 178/431 (41%), Positives = 253/431 (58%), Gaps = 39/431 (9%)

Query: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300
           D  W  ++ E ++ LP GW ++ D +GTYYWH+P+G+TQW+ P                 
Sbjct: 17  DDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRP----------------- 59

Query: 301 TWT-GFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLS-PEPLPQEEEKL 358
           TW  G A   G      W            GL+ P+  + +    SL     L     + 
Sbjct: 60  TWELGDAEDPGTGTEGIW------------GLRPPKGRSFSSLESSLDRSNSLSWYGGES 107

Query: 359 PPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGE 418
             ++  PG KCFAVRSLGWVE+ EE+LAPG+SS+AVNNCI+QL+  ++    P  G WGE
Sbjct: 108 YIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPP-DGAWGE 166

Query: 419 GKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRD--FAYVARDKLTQMLK 476
           G+++L+ L+ + + LV P   +L+H QP++ IRVWGVG   GRD  FA+VA DK + MLK
Sbjct: 167 GQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLK 226

Query: 477 CHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNE 536
           CHVF C+ PAK IA++LH +C++I++ER       +  S D     D+P QVE     ++
Sbjct: 227 CHVFCCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQ 286

Query: 537 LVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTE 596
             QK++  Y+G +PV K +G+DV+N A+ ++ +   R  W P+ +SV+ + +T    Q E
Sbjct: 287 AAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAE 346

Query: 597 AV-----LGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAA 651
           A      L +C VR ++F+ VGRD HTF  I   G  SF C  FWC+P+A  LSEAVQAA
Sbjct: 347 ASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAA 406

Query: 652 CMLRYQKCLDA 662
           CM++YQKCL A
Sbjct: 407 CMVQYQKCLVA 417


>gi|95147536 amyloid beta precursor protein-binding, family B,
           member 3 isoform c [Homo sapiens]
          Length = 491

 Score =  331 bits (848), Expect = 2e-90
 Identities = 178/436 (40%), Positives = 253/436 (58%), Gaps = 44/436 (10%)

Query: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300
           D  W  ++ E ++ LP GW ++ D +GTYYWH+P+G+TQW+ P                 
Sbjct: 17  DDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRP----------------- 59

Query: 301 TWT-GFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLS-PEPLPQEEEKL 358
           TW  G A   G      W            GL+ P+  + +    SL     L     + 
Sbjct: 60  TWELGDAEDPGTGTEGIW------------GLRPPKGRSFSSLESSLDRSNSLSWYGGES 107

Query: 359 PPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGE 418
             ++  PG KCFAVRSLGWVE+ EE+LAPG+SS+AVNNCI+QL+  ++    P  G WGE
Sbjct: 108 YIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPP-DGAWGE 166

Query: 419 GKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGR-------DFAYVARDKL 471
           G+++L+ L+ + + LV P   +L+H QP++ IRVWGVG   GR       DFA+VA DK 
Sbjct: 167 GQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRPISAPARDFAFVASDKD 226

Query: 472 TQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFP 531
           + MLKCHVF C+ PAK IA++LH +C++I++ER       +  S D     D+P QVE  
Sbjct: 227 SCMLKCHVFCCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELL 286

Query: 532 APKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTIL 591
              ++  QK++  Y+G +PV K +G+DV+N A+ ++ +   R  W P+ +SV+ + +T  
Sbjct: 287 DAVSQAAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAH 346

Query: 592 HQQTEAV-----LGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSE 646
             Q EA      L +C VR ++F+ VGRD HTF  I   G  SF C  FWC+P+A  LSE
Sbjct: 347 PIQAEASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSE 406

Query: 647 AVQAACMLRYQKCLDA 662
           AVQAACM++YQKCL A
Sbjct: 407 AVQAACMVQYQKCLVA 422


>gi|95147538 amyloid beta precursor protein-binding, family B,
           member 3 isoform d [Homo sapiens]
          Length = 493

 Score =  330 bits (846), Expect = 3e-90
 Identities = 178/438 (40%), Positives = 253/438 (57%), Gaps = 46/438 (10%)

Query: 241 DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300
           D  W  ++ E ++ LP GW ++ D +GTYYWH+P+G+TQW+ P                 
Sbjct: 17  DDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRP----------------- 59

Query: 301 TWT-GFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLS-PEPLPQEEEKL 358
           TW  G A   G      W            GL+ P+  + +    SL     L     + 
Sbjct: 60  TWELGDAEDPGTGTEGIW------------GLRPPKGRSFSSLESSLDRSNSLSWYGGES 107

Query: 359 PPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGE 418
             ++  PG KCFAVRSLGWVE+ EE+LAPG+SS+AVNNCI+QL+  ++    P  G WGE
Sbjct: 108 YIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPP-DGAWGE 166

Query: 419 GKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRD---------FAYVARD 469
           G+++L+ L+ + + LV P   +L+H QP++ IRVWGVG   GRD         FA+VA D
Sbjct: 167 GQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDSPISAPARDFAFVASD 226

Query: 470 KLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVE 529
           K + MLKCHVF C+ PAK IA++LH +C++I++ER       +  S D     D+P QVE
Sbjct: 227 KDSCMLKCHVFCCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVE 286

Query: 530 FPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLT 589
                ++  QK++  Y+G +PV K +G+DV+N A+ ++ +   R  W P+ +SV+ + +T
Sbjct: 287 LLDAVSQAAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMT 346

Query: 590 ILHQQTEAV-----LGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASL 644
               Q EA      L +C VR ++F+ VGRD HTF  I   G  SF C  FWC+P+A  L
Sbjct: 347 AHPIQAEASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGL 406

Query: 645 SEAVQAACMLRYQKCLDA 662
           SEAVQAACM++YQKCL A
Sbjct: 407 SEAVQAACMVQYQKCLVA 424


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 58/232 (25%), Positives = 92/232 (39%), Gaps = 29/232 (12%)

Query: 140  STQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGP 199
            S  E+     EE+ A E EEEE+DDDD+ ++ D S      E  +   A        +G 
Sbjct: 1040 SLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES------ENDDEDTALSEASEKDEGD 1093

Query: 200  REHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGW 259
             +  ++ S++     + +S E S  +     S S  SP  ++      A E + +     
Sbjct: 1094 SDEEETVSIVTSKAEATSSSESSESSEFESSSES--SPSSSEDEEEVVAREEEEEEEEEE 1151

Query: 260  MRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKD 319
            M  +++  +       G   +E  G  +     +P  +S     G       E      +
Sbjct: 1152 MVAEESMAS------AGPEDFEQDGEEAALAPGAPAVDS----LGMEEEVDIETEAVAPE 1201

Query: 320  E-PS--DEAPMELGLKEP--------EEGTLTFPAQSLSPEPLPQEEEKLPP 360
            E PS  DE P+ +G++EP        E G     A  LSPEP  +E E  PP
Sbjct: 1202 ERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPP 1253


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 65/281 (23%), Positives = 105/281 (37%), Gaps = 50/281 (17%)

Query: 98   EASQEPEMAPLGPKGLIHLYSELELSAHNAANRGLRGPGLIISTQEQGPDEGE------- 150
            EAS+E    P  P        E E  A      G + P      +E+G  +G+       
Sbjct: 905  EASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPK---RDEERGKTQGKHRKSFAL 961

Query: 151  ----EKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSA 206
                E+A+ E+  E++++DDEE+EED        +  E+V+   +   ++DG  E S S+
Sbjct: 962  DSEGEEASQESSSEKDEEDDEEDEED-------EDREEAVDTTKKETEVSDGEDEESDSS 1014

Query: 207  SLL-----FGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMR 261
            S           N + SD +SS ++ S  S S  S   + S  + ++ E + +       
Sbjct: 1015 SKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEER---- 1070

Query: 262  VQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQE---ESQLTWTGFAHGEGFEDGEFWK 318
                        P       PP R  P    +P E     ++  +        E      
Sbjct: 1071 ------------PAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARP 1118

Query: 319  DEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLP 359
              P++E+P    L+ PE      PA   +P P P E    P
Sbjct: 1119 AGPTEESPPSAPLRPPEP-----PAGPPAPAPRPDERPSSP 1154



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 30/123 (24%)

Query: 128  ANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSP----------- 176
            A+  L  P ++++  E+   +  ++   E EEE E++ +EEEEE   S            
Sbjct: 1332 ADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRR 1391

Query: 177  -----------PGLPEPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWA 225
                       P  P P      PP P+A    PR   +  ++L+ + NS    ED S+ 
Sbjct: 1392 RSLRSHARRRRPPPPPP------PPPPRAYE--PRSEFEQMTILYDIWNSGLDSEDMSYL 1443

Query: 226  TLS 228
             L+
Sbjct: 1444 RLT 1446



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 54/253 (21%), Positives = 83/253 (32%), Gaps = 24/253 (9%)

Query: 127  AANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESV 186
            A   GLRG   + S + +  +  E   A E +        EE+E+D        EP    
Sbjct: 879  AFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPG 938

Query: 187  EAPPR---PQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSF 243
              PP+    +  T G  +H KS +L        AS E SS              ED D  
Sbjct: 939  TKPPKRDEERGKTQG--KHRKSFAL--DSEGEEASQESSS---EKDEEDDEEDEEDEDRE 991

Query: 244  WNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQLTWT 303
               +  + ++++  G     D+S     +  +           S S  SS    S  + +
Sbjct: 992  EAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSS 1051

Query: 304  GFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQ---------- 353
              +        E   DE  +E P  L    P    +  P  +    P+P+          
Sbjct: 1052 SSSSSSSESSSE---DEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPL 1108

Query: 354  -EEEKLPPRNTNP 365
             E+E  P R   P
Sbjct: 1109 PEQEASPARPAGP 1121


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 61/237 (25%), Positives = 87/237 (36%), Gaps = 50/237 (21%)

Query: 150  EEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLL 209
            EE  A  + E E +++ EEEEE+   PP     +   EA  R  AL  G  E    AS  
Sbjct: 928  EEDVASSSSESEMEEEGEEEEEEPRLPPSDLGGVPWKEA-VRIHALLKGKSEEELEASKS 986

Query: 210  FGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDT---- 265
            FG  N    +E+  +    +        ED D        E +    AG  R+Q      
Sbjct: 987  FGPGNEEEEEEEEEYEEEEE--------EDYDE-------EEEESSEAGNQRLQQVMHAA 1031

Query: 266  ------SGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQL-----TWTGFAHGEGFEDG 314
                  +  ++ HI     +      +  S   +P +E+ L     +      GE  EDG
Sbjct: 1032 DPLEIQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDG 1091

Query: 315  ------------EFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLP 359
                        + W D PSD A  EL L  P EG      +      + ++EEKLP
Sbjct: 1092 DPGDTGAELDDDQHWSDSPSD-ADRELRLPCPAEGEAELELR------VSEDEEKLP 1141



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 84/300 (28%), Positives = 111/300 (37%), Gaps = 74/300 (24%)

Query: 97   EEASQEPEMAPLGPKGL-------IHLY----SELELSAHNAANRGLRGPGLIISTQEQG 145
            EE  +EP + P    G+       IH      SE EL A  +      GPG         
Sbjct: 945  EEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSF-----GPG--------- 990

Query: 146  PDEGEEKAAGEAEEEEEDDDDEEEEED-------LSSPPGLPEPLESVEAPPRPQALTDG 198
             +E EE+   E EEEEE+D DEEEEE        L       +PLE ++A      + + 
Sbjct: 991  -NEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLE-IQADVHWTHIRER 1048

Query: 199  PREH------SKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDT------DSFWNP 246
              E         SAS      N    D DS  A +   +   G P DT      D  W+ 
Sbjct: 1049 EEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHWSD 1108

Query: 247  NAFETDSDL----PA-GWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSP---QEES 298
            +  + D +L    PA G   ++         +P      E      PSQ +SP    +ES
Sbjct: 1109 SPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQE----RGPSQATSPIRSPQES 1164

Query: 299  QLTWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEP-LPQEEEK 357
             L +    H    E  +     P   A  E   K PEE         L PEP LP+E+ K
Sbjct: 1165 ALLFIP-VHSPSTEGPQL---PPVPAATQE---KSPEE--------RLFPEPLLPKEKPK 1209


>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
          Length = 224

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 118 SELELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPP 177
           SELE      A      P    S+   GPD+ EE    E EEEEE++++EEEEE+ + PP
Sbjct: 15  SELEEEEEEEAATSSSSPSS--SSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPP 72



 Score = 33.9 bits (76), Expect = 0.53
 Identities = 15/56 (26%), Positives = 27/56 (48%)

Query: 142 QEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTD 197
           +E         ++      ++D++DEEEEE+        E  E  EAPP P+ +++
Sbjct: 23  EEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSE 78


>gi|46276863 parathymosin [Homo sapiens]
          Length = 102

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 2/63 (3%)

Query: 138 IISTQEQGPDEGEEKAAGEAEEEEE-DDDDEEEEEDLSSPPGLPEPLESV-EAPPRPQAL 195
           ++  +E G +E EE+ A + EEE+E +++DEEEEE+    P L    E   EA P+ Q  
Sbjct: 37  VVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKT 96

Query: 196 TDG 198
            +G
Sbjct: 97  ENG 99


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 25/132 (18%)

Query: 69   WLKEGQNQLRRAATAHRD----QNRNVTLTLAEEASQEPEMAPL-GPKGLIHLYSELELS 123
            W KE Q  L   A + +     Q++N  L         PE  P+ G +G +     LELS
Sbjct: 1018 WEKEEQEILSTRANSRQSPAKVQSKNKYL-------HSPESRPVTGERGQL-----LELS 1065

Query: 124  AHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPL 183
              ++              +++  +E EE+   + EEEEE++++EEEE   SSPP L +P 
Sbjct: 1066 KESSEEEE--------EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117

Query: 184  ESVEAPPRPQAL 195
                   RP  L
Sbjct: 1118 SVAIKRKRPFVL 1129



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 11/96 (11%)

Query: 146  PDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKS 205
            P++   K   E EEEEE++++EEEEE      G      +VE  P      DG +   K 
Sbjct: 1343 PEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGG-----GNVEKDP------DGAKSQEKE 1391

Query: 206  ASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTD 241
               +   +  +A  +D          PS+    D D
Sbjct: 1392 EPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDAD 1427



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 139  ISTQEQGPDEGEE----KAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQA 194
            + + E  P  GE     + + E+ EEEE+++DEEEEE+        E  E  E     + 
Sbjct: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105

Query: 195  LTDGPREHSKSASL 208
            +   P   +K  S+
Sbjct: 1106 IQSSPPRLTKPQSV 1119



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 5/83 (6%)

Query: 146  PDEGEEKAAGEAEEEEEDDDDEEE-----EEDLSSPPGLPEPLESVEAPPRPQALTDGPR 200
            P+E EE+   E EEEEE++ +EEE     E+D        +    +       A  D   
Sbjct: 1350 PEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHE 1409

Query: 201  EHSKSASLLFGMRNSAASDEDSS 223
            E  +         +  A DED S
Sbjct: 1410 EEEEEDEEPSHNEDHDADDEDDS 1432


>gi|189181750 human immunodeficiency virus type I enhancer binding
            protein 3 b [Homo sapiens]
          Length = 2405

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 66/272 (24%), Positives = 96/272 (35%), Gaps = 36/272 (13%)

Query: 160  EEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREH---SKSASLLFGMRNSA 216
            EE D  D E E     PP  PE  E  + P R Q L   P E     K    L  M  S+
Sbjct: 862  EEPDRPDTEPEP----PPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSS 917

Query: 217  ASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETD------SDLPAGWMRVQDTSGTYY 270
                  S   LS+ SPS  S           +FE D      +  P+  MR +   GT+ 
Sbjct: 918  GESSFESSVPLSR-SPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPL-GTHM 975

Query: 271  WHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPMELG 330
              +P+         R++  Q  +    + +T T     + F+ G      PS  AP+   
Sbjct: 976  LTVPSHHPHAREMRRSASEQSPNVSHSAHMTET---RSKSFDYGSLSLTGPSAPAPVAPP 1032

Query: 331  LK-EPEEGTLTFPAQSLSPEPLPQEEEKLPPRNTNPGIKCFAVRSLGWVEMTEEELAPGR 389
             +  P E    F  +  S    P+ E ++ P+                     EE  P  
Sbjct: 1033 ARVAPPERRKCFLVRQASLSRPPESELEVAPKG----------------RQESEEPQPSS 1076

Query: 390  SSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKD 421
            S  +  + + Q+S    + H    GG G G+D
Sbjct: 1077 SKPSAKSSLSQISSAATS-HGGPPGGKGPGQD 1107



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 9/74 (12%)

Query: 159  EEEEDDDDEEEEEDLS------SPPGLPEPLESVEAP---PRPQALTDGPREHSKSASLL 209
            +E+ED+D+EE +++LS       PPG P  L +  +P   P+P        E ++ +S+ 
Sbjct: 1860 DEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVS 1919

Query: 210  FGMRNSAASDEDSS 223
               R +A+S   SS
Sbjct: 1920 EAERLTASSCSMSS 1933



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 17/98 (17%)

Query: 151 EKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLLF 210
           E+  GE  EE  + +  + EE+ S+  G P      E  PRP           K   L  
Sbjct: 266 ERIPGEEFEEPTEGESTDSEEETSATSGHP-----AELSPRP-----------KQPLLSS 309

Query: 211 GMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNA 248
           G+ +S +        +LSQ S +  S ED   F  P++
Sbjct: 310 GLYSSGSHSSSHERCSLSQSSTAQ-SLEDPPPFVEPSS 346


>gi|116089331 human immunodeficiency virus type I enhancer binding
            protein 3 [Homo sapiens]
          Length = 2406

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 66/272 (24%), Positives = 96/272 (35%), Gaps = 36/272 (13%)

Query: 160  EEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREH---SKSASLLFGMRNSA 216
            EE D  D E E     PP  PE  E  + P R Q L   P E     K    L  M  S+
Sbjct: 862  EEPDRPDTEPEP----PPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSS 917

Query: 217  ASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETD------SDLPAGWMRVQDTSGTYY 270
                  S   LS+ SPS  S           +FE D      +  P+  MR +   GT+ 
Sbjct: 918  GESSFESSVPLSR-SPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPL-GTHM 975

Query: 271  WHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPMELG 330
              +P+         R++  Q  +    + +T T     + F+ G      PS  AP+   
Sbjct: 976  LTVPSHHPHAREMRRSASEQSPNVSHSAHMTET---RSKSFDYGSLSLTGPSAPAPVAPP 1032

Query: 331  LK-EPEEGTLTFPAQSLSPEPLPQEEEKLPPRNTNPGIKCFAVRSLGWVEMTEEELAPGR 389
             +  P E    F  +  S    P+ E ++ P+                     EE  P  
Sbjct: 1033 ARVAPPERRKCFLVRQASLSRPPESELEVAPKG----------------RQESEEPQPSS 1076

Query: 390  SSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKD 421
            S  +  + + Q+S    + H    GG G G+D
Sbjct: 1077 SKPSAKSSLSQISSAATS-HGGPPGGKGPGQD 1107



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 9/74 (12%)

Query: 159  EEEEDDDDEEEEEDLS------SPPGLPEPLESVEAP---PRPQALTDGPREHSKSASLL 209
            +E+ED+D+EE +++LS       PPG P  L +  +P   P+P        E ++ +S+ 
Sbjct: 1860 DEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVS 1919

Query: 210  FGMRNSAASDEDSS 223
               R +A+S   SS
Sbjct: 1920 EAERLTASSCSMSS 1933



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 17/98 (17%)

Query: 151 EKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLLF 210
           E+  GE  EE  + +  + EE+ S+  G P      E  PRP           K   L  
Sbjct: 266 ERIPGEEFEEPTEGESTDSEEETSATSGHP-----AELSPRP-----------KQPLLSS 309

Query: 211 GMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNA 248
           G+ +S +        +LSQ S +  S ED   F  P++
Sbjct: 310 GLYSSGSHSSSHERCSLSQSSTAQ-SLEDPPPFVEPSS 346


>gi|239747212 PREDICTED: hypothetical protein XP_002346939 [Homo
            sapiens]
          Length = 1158

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 153  AAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLLFGM 212
            A+ + E+ EE+DDD+ EE+D  S  G  +  ++V   P PQA  +   +   +ASL  G 
Sbjct: 1012 ASEKQEDVEEEDDDDLEEDDEDSLAGKSQD-DTVSPAPEPQAAYEDEEDEEPAASLAVGF 1070

Query: 213  RNSAASDEDSSWATLS-QGSPSYGSPED 239
             ++    ED     L+ +  P++G   D
Sbjct: 1071 DHTRRCAEDHEGGLLALEPMPTFGKGLD 1098


>gi|41349472 PR domain containing 16 isoform 2 [Homo sapiens]
          Length = 1256

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 153  AAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLLFGM 212
            A+ + E+ EE+DDD+ EE+D  S  G  +  ++V   P PQA  +   +   +ASL  G 
Sbjct: 1110 ASEKQEDVEEEDDDDLEEDDEDSLAGKSQD-DTVSPAPEPQAAYEDEEDEEPAASLAVGF 1168

Query: 213  RNSAASDEDSSWATLS-QGSPSYGSPED 239
             ++    ED     L+ +  P++G   D
Sbjct: 1169 DHTRRCAEDHEGGLLALEPMPTFGKGLD 1196


>gi|41349470 PR domain containing 16 isoform 1 [Homo sapiens]
          Length = 1275

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 153  AAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLLFGM 212
            A+ + E+ EE+DDD+ EE+D  S  G  +  ++V   P PQA  +   +   +ASL  G 
Sbjct: 1110 ASEKQEDVEEEDDDDLEEDDEDSLAGKSQD-DTVSPAPEPQAAYEDEEDEEPAASLAVGF 1168

Query: 213  RNSAASDEDSSWATLS-QGSPSYGSPED 239
             ++    ED     L+ +  P++G   D
Sbjct: 1169 DHTRRCAEDHEGGLLALEPMPTFGKGLD 1196


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 1/47 (2%)

Query: 255  LPAGWMRVQDTSGT-YYWHIPTGTTQWEPPGRASPSQGSSPQEESQL 300
            LP  W   +D  G  YY+H+ T  TQW+PP   SP   +S + E+++
Sbjct: 2391 LPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEM 2437


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 27/118 (22%)

Query: 142  QEQGPDEGEEKAAGEAEEEEEDDDDEEEEE-----DLS-------------SPPGLPEPL 183
            +E+  +E  E+  GE EEEEE++D+EEEEE     DL               PP LP  L
Sbjct: 927  EEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPAL 986

Query: 184  ESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDE---DSSWATLSQGSPSYGSPE 238
               E+PP+ Q       E      LL  +      +E   D++     +  PS G  E
Sbjct: 987  PPPESPPKVQP------EPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVE 1038



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 17/34 (50%), Positives = 25/34 (73%)

Query: 139 ISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEED 172
           I++ ++  +E EE+   E EEEEE++D EEEEED
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEED 916



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 17/35 (48%), Positives = 25/35 (71%)

Query: 138 IISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEED 172
           I S+ E+  +E EE+   E EEEEE+D +EEEE++
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE 917



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 16/33 (48%), Positives = 24/33 (72%)

Query: 140 STQEQGPDEGEEKAAGEAEEEEEDDDDEEEEED 172
           S +E+  +E EE+   E EEEEED ++EEE+E+
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEE 918



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 54/219 (24%), Positives = 77/219 (35%), Gaps = 29/219 (13%)

Query: 142  QEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPRE 201
            +E+  +E EE+   E  EEEE+D++E  EE+        E  E  E     +   +   E
Sbjct: 894  EEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEE 953

Query: 202  H---SKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAG 258
                 +   L FG       +      TL    P   SP        P         P  
Sbjct: 954  EEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP--------PKVQPEPEPEPGL 1005

Query: 259  WMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWK 318
             + V++          T  T       A PSQG   +E       G +   G    E  +
Sbjct: 1006 LLEVEEPGTEEERGADTAPTL---APEALPSQGEVERE-------GESPAAGPPPQELVE 1055

Query: 319  DEPSDEAPMELGLKEPEEGTLTFPAQSLSPEP-LPQEEE 356
            +EPS  AP  L  +E E+G     +  + P P  P EEE
Sbjct: 1056 EEPS--APPTLLEEETEDG-----SDKVQPPPETPAEEE 1087


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 32/181 (17%)

Query: 135 PGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSP---------PGLPEPLES 185
           PGL  S+ E   +E   +++ E EEEEED++DEEEEE  SS            L E L +
Sbjct: 471 PGLAKSSSESSSEESSSESSSE-EEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRA 529

Query: 186 VEAPPRPQALTDGP---------REHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGS 236
           V    +  AL+ GP         ++  K        R  A +DED       +      S
Sbjct: 530 VH--EQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKS 587

Query: 237 PEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQE 296
            + + S     A       P+G       SGT    +P   T+  PP  A P+   S +E
Sbjct: 588 KKASGSGGGSAALGPSGFGPSG------GSGT---KLPKKATKTAPP--ALPTGYDSEEE 636

Query: 297 E 297
           E
Sbjct: 637 E 637


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 32/181 (17%)

Query: 135 PGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSP---------PGLPEPLES 185
           PGL  S+ E   +E   +++ E EEEEED++DEEEEE  SS            L E L +
Sbjct: 471 PGLAKSSSESSSEESSSESSSE-EEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRA 529

Query: 186 VEAPPRPQALTDGP---------REHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGS 236
           V    +  AL+ GP         ++  K        R  A +DED       +      S
Sbjct: 530 VH--EQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKS 587

Query: 237 PEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQE 296
            + + S     A       P+G       SGT    +P   T+  PP  A P+   S +E
Sbjct: 588 KKASGSGGGSAALGPSGFGPSG------GSGT---KLPKKATKTAPP--ALPTGYDSEEE 636

Query: 297 E 297
           E
Sbjct: 637 E 637


>gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]
          Length = 1606

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 73/305 (23%), Positives = 116/305 (38%), Gaps = 51/305 (16%)

Query: 36  LNAKLQATAVGPKDLRSAMGEGGGP---EPGPANAKWLKEGQNQLRRAATAHRDQNRNVT 92
           L+ + ++  +    + + M  G G    E   ++  W  E   QL   +      N+++ 
Sbjct: 355 LSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPE---QLGEGSVPDGPGNQSIE 411

Query: 93  LTL-AEEASQEPE-----MAPLGPKGLIHLYSELEL------SAHNAANR---GLRGPGL 137
           L+  AEEA+   E     M  +GP+G   L ++++       SA   A +   G     L
Sbjct: 412 LSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASAL 471

Query: 138 IISTQEQGPDEGEEKAAGEA--------EEEEEDDDDEEEEEDLSSPPGLPEPLESVEAP 189
           ++   E      EE    EA        EEEE++ ++E +   L    G  +   SV+  
Sbjct: 472 LLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRK 531

Query: 190 PRPQAL---------------TDGPREH-SKSASLLFGMRN----SAASDEDSS--WATL 227
            RP +L                + PR H  +  +LL  M +    SAA +ED +   +TL
Sbjct: 532 SRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTL 591

Query: 228 SQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRAS 287
              S   G  E      +P+A E D + P G        G    H P+        G   
Sbjct: 592 KDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTH 651

Query: 288 PSQGS 292
           PS GS
Sbjct: 652 PSTGS 656


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 49/182 (26%), Positives = 67/182 (36%), Gaps = 25/182 (13%)

Query: 38  AKLQATAVGPKDLRSAMGEGGGPEPGPANAKWLKEGQNQLRRAATAHRDQNR------NV 91
           A+ ++T   P +     GEG   E      +   EG+ + +       D+N       N 
Sbjct: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807

Query: 92  TLTLAEEASQEPEMAPLGPKGLIHLYSELELSAHNAANRGLRGPGLIISTQEQGPD---E 148
                E  +++ EM     KG        ELSA N         G+       G D   E
Sbjct: 808 GEDEGEIHAEDGEM-----KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEE 862

Query: 149 GEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASL 208
            EE+   E EEEEE+ ++EEEEE+     G  EPL             D P    K A  
Sbjct: 863 EEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLS-----------LDWPETRQKQAIY 911

Query: 209 LF 210
           LF
Sbjct: 912 LF 913


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 7/71 (9%)

Query: 142 QEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEP--LESVEAPPRPQALT--- 196
           ++   DE ++    E EEEEE++DD+++ ED +    LP+P  +   ++P +   LT   
Sbjct: 140 EDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQSPSKTDHLTEKA 199

Query: 197 --DGPREHSKS 205
             D PR+   S
Sbjct: 200 YSDTPRDFPDS 210


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 1/116 (0%)

Query: 127 AANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESV 186
           A+    +  G++   +E   +E EE+   E EEEEE++++EEEEE+        E  E  
Sbjct: 244 ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303

Query: 187 EAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDS 242
           E    P  +      H+ SA     +R   +      ++ + +        EDT S
Sbjct: 304 EEEAAPDVIFQEDTSHT-SAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHS 358



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/168 (26%), Positives = 63/168 (37%), Gaps = 33/168 (19%)

Query: 95  LAEEASQEPEM---APLGPKGLIHLYSEL-ELSAHNAANRGL----------------RG 134
           +AEE   E ++   A  GP G++HL  E  E +A     +GL                R 
Sbjct: 174 IAEETLVEEDLGQAAKPGP-GIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERS 232

Query: 135 PGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQA 194
             L   + E    E   K  G    EEED+++EEEEE+        E  E  E     + 
Sbjct: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEE 292

Query: 195 LTDGPREHSKSASLLFGMRNSAASD----EDSSWATLSQGSPSYGSPE 238
             +   E  +           AA D    ED+S  T +Q +P    PE
Sbjct: 293 EEEEEEEEEEE-------EEEAAPDVIFQEDTS-HTSAQKAPELRGPE 332


>gi|10863935 reticulon 1 isoform A [Homo sapiens]
          Length = 776

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 48/194 (24%), Positives = 69/194 (35%), Gaps = 31/194 (15%)

Query: 18  GGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEG-------GGPEPGPANAKWL 70
           G P +  PL   A+  +  +++++  +  P     A+  G       GGP P PA+    
Sbjct: 391 GPPTIPSPLDHEASSAESGDSEIELVSEDPMAAEDALPSGYVSFGHVGGPPPSPASPSIQ 450

Query: 71  KEGQNQLRRAATAHRDQNRNVTLTLAEEASQEP-----EMAPLGPKGLIHLYSELELSAH 125
               + LR    A  D    +    A  AS+E      +  P+ P  L  +  E  + A 
Sbjct: 451 ---YSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPSALDAIREETGVRAE 507

Query: 126 NAA--NRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDD----DDEEEEEDLSSP--- 176
             A   RGL  PG  +      P  G E   G+   E E        EE+     SP   
Sbjct: 508 ERAPSRRGLAEPGSFLDYPSTEPQPGPELPPGDGALEPETPMLPRKPEEDSSSNQSPAAT 567

Query: 177 -------PGLPEPL 183
                  PG P PL
Sbjct: 568 KGPGPLGPGAPPPL 581


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/65 (40%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 140 STQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPP---RPQALT 196
           S+  +  +E EE+   EAEEEEE++D EE    L SPP    P E  + PP   + QA  
Sbjct: 309 SSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL-SPPQPASPAEEDKMPPYDEQTQAFI 367

Query: 197 DGPRE 201
           D  +E
Sbjct: 368 DAAQE 372



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 48/214 (22%), Positives = 82/214 (38%), Gaps = 58/214 (27%)

Query: 150 EEKAAGEAEEEEE--DDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSAS 207
           E+ AA +A++E+E   D  +E ++D+     + E    ++  P      DG    +++ +
Sbjct: 200 EQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE----LQTHPELDTDGDGALSEAEAQA 255

Query: 208 LLFG-MRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTS 266
           LL G  +  A S  D  WA +     S   P D  +   P+  E   +            
Sbjct: 256 LLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEE------------ 303

Query: 267 GTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAP 326
                         +PP  +SP++    +EE +         E  E+ E  ++E S+EAP
Sbjct: 304 --------------QPPVPSSPTEEEEEEEEEE--------EEEAEEEE--EEEDSEEAP 339

Query: 327 MELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPP 360
             L   +P                 P EE+K+PP
Sbjct: 340 PPLSPPQPAS---------------PAEEDKMPP 358


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 143 EQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEA-PPRPQALTDGPRE 201
           E+ P E     +   E+  ED++DE  EE+ +S     E  ES E+   + Q+  D   E
Sbjct: 486 EEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEE 545

Query: 202 HSKSASLLFGMRNSAASDEDSSWATLSQGSPSYG 235
                   FG+    A DE+ S A    G P+ G
Sbjct: 546 DDD-----FGVEYLLARDEEQSEADAGSGPPTPG 574



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 17/62 (27%), Positives = 30/62 (48%)

Query: 140 STQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGP 199
           S  E+   E  E A  +++ +EE++DD+   E L +        ++   PP P   T GP
Sbjct: 521 SASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEADAGSGPPTPGPTTLGP 580

Query: 200 RE 201
           ++
Sbjct: 581 KK 582



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 5/115 (4%)

Query: 150 EEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLL 209
           ++ A   A      +D++E+E D +S    PE     E PP+  + +       +S    
Sbjct: 449 QQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSED-- 506

Query: 210 FGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQD 264
               +  + +E++S ++ S+ S S  S ED  S    +  E D D    ++  +D
Sbjct: 507 --EEDEHSEEEETSGSSASEESESEES-EDAQSQSQADEEEEDDDFGVEYLLARD 558



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 13/95 (13%)

Query: 98  EASQEPEMAPLGPKGLIHLYSELELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEA 157
           EA + P+         +   SE E   H+         G   S + +  +  + ++  +A
Sbjct: 484 EAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEET---SGSSASEESESEESEDAQSQSQA 540

Query: 158 EEEEEDD----------DDEEEEEDLSSPPGLPEP 182
           +EEEEDD          D+E+ E D  S P  P P
Sbjct: 541 DEEEEDDDFGVEYLLARDEEQSEADAGSGPPTPGP 575


>gi|194688135 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 22/57 (38%), Positives = 36/57 (63%), Gaps = 8/57 (14%)

Query: 119 ELELSAHNAANR---GLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEED 172
           E +++A+ A  +   G +GPG    ++++   E EE+     EEEEED+D+EEE+ED
Sbjct: 156 EKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEE-----EEEEEDEDEEEEDED 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,015,927
Number of Sequences: 37866
Number of extensions: 1856937
Number of successful extensions: 22034
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 376
Number of HSP's successfully gapped in prelim test: 386
Number of HSP's that attempted gapping in prelim test: 12115
Number of HSP's gapped (non-prelim): 5030
length of query: 708
length of database: 18,247,518
effective HSP length: 109
effective length of query: 599
effective length of database: 14,120,124
effective search space: 8457954276
effective search space used: 8457954276
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.