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Search of human proteins with 115298682
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
(2817 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 5641 0.0
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 387 e-107
gi|149192855 HLA-B associated transcript 2-like [Homo sapiens] 362 2e-99
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 139 3e-32
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 132 6e-30
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 132 6e-30
gi|116284392 mucin 2 precursor [Homo sapiens] 127 2e-28
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 126 3e-28
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 126 3e-28
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 125 5e-28
gi|91982772 mucin 17 [Homo sapiens] 123 3e-27
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 122 4e-27
gi|148746195 trichohyalin [Homo sapiens] 120 1e-26
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 118 7e-26
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 117 2e-25
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 116 4e-25
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 116 4e-25
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 115 8e-25
gi|151301154 mucin 6, gastric [Homo sapiens] 111 9e-24
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 110 2e-23
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 108 6e-23
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 108 7e-23
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 108 7e-23
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 108 7e-23
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 108 7e-23
gi|163965366 nascent polypeptide-associated complex alpha subuni... 106 3e-22
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 105 8e-22
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 104 1e-21
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 104 1e-21
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 104 1e-21
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 5641 bits (14633), Expect = 0.0
Identities = 2817/2817 (100%), Positives = 2817/2817 (100%)
Query: 1 MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTARHGLQSLGKVGISRRMPPPANL 60
MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTARHGLQSLGKVGISRRMPPPANL
Sbjct: 1 MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTARHGLQSLGKVGISRRMPPPANL 60
Query: 61 PSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPPAQPKPGVAAPPEVAPAPKS 120
PSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPPAQPKPGVAAPPEVAPAPKS
Sbjct: 61 PSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPPAQPKPGVAAPPEVAPAPKS 120
Query: 121 WASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKEKETNDDNYGPGPSLRPPNVACWRD 180
WASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKEKETNDDNYGPGPSLRPPNVACWRD
Sbjct: 121 WASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKEKETNDDNYGPGPSLRPPNVACWRD 180
Query: 181 GGKAAGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAKLNGQQAALASQ 240
GGKAAGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAKLNGQQAALASQ
Sbjct: 181 GGKAAGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAKLNGQQAALASQ 240
Query: 241 YRAMMPPYMFQQYPRMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSAS 300
YRAMMPPYMFQQYPRMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSAS
Sbjct: 241 YRAMMPPYMFQQYPRMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSAS 300
Query: 301 ELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASEN 360
ELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASEN
Sbjct: 301 ELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASEN 360
Query: 361 NENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPP 420
NENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPP
Sbjct: 361 NENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPP 420
Query: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA 480
DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA
Sbjct: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA 480
Query: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE 540
CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE
Sbjct: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE 540
Query: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600
KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI
Sbjct: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600
Query: 601 EPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVL 660
EPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVL
Sbjct: 601 EPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVL 660
Query: 661 SGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQP 720
SGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQP
Sbjct: 661 SGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQP 720
Query: 721 MQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSP 780
MQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSP
Sbjct: 721 MQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSP 780
Query: 781 NSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQ 840
NSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQ
Sbjct: 781 NSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQ 840
Query: 841 EQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPD 900
EQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPD
Sbjct: 841 EQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPD 900
Query: 901 QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPI 960
QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPI
Sbjct: 901 QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPI 960
Query: 961 ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV 1020
ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV
Sbjct: 961 ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV 1020
Query: 1021 LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPI 1080
LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPI
Sbjct: 1021 LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPI 1080
Query: 1081 QPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEK 1140
QPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEK
Sbjct: 1081 QPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEK 1140
Query: 1141 VISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSY 1200
VISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSY
Sbjct: 1141 VISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSY 1200
Query: 1201 RGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQ 1260
RGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQ
Sbjct: 1201 RGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQ 1260
Query: 1261 RGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEK 1320
RGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEK
Sbjct: 1261 RGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEK 1320
Query: 1321 PYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQS 1380
PYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQS
Sbjct: 1321 PYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQS 1380
Query: 1381 EVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRL 1440
EVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRL
Sbjct: 1381 EVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRL 1440
Query: 1441 REREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETAS 1500
REREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETAS
Sbjct: 1441 REREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETAS 1500
Query: 1501 ESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGP 1560
ESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGP
Sbjct: 1501 ESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGP 1560
Query: 1561 PKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKN 1620
PKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKN
Sbjct: 1561 PKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKN 1620
Query: 1621 SKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDG 1680
SKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDG
Sbjct: 1621 SKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDG 1680
Query: 1681 FTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQA 1740
FTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQA
Sbjct: 1681 FTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQA 1740
Query: 1741 QSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAP 1800
QSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAP
Sbjct: 1741 QSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAP 1800
Query: 1801 VPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASAS 1860
VPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASAS
Sbjct: 1801 VPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASAS 1860
Query: 1861 IPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVS 1920
IPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVS
Sbjct: 1861 IPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVS 1920
Query: 1921 APNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQT 1980
APNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQT
Sbjct: 1921 APNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQT 1980
Query: 1981 PQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAK 2040
PQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAK
Sbjct: 1981 PQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAK 2040
Query: 2041 NGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQK 2100
NGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQK
Sbjct: 2041 NGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQK 2100
Query: 2101 LPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKA 2160
LPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKA
Sbjct: 2101 LPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKA 2160
Query: 2161 VSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPN 2220
VSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPN
Sbjct: 2161 VSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPN 2220
Query: 2221 TLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATG 2280
TLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATG
Sbjct: 2221 TLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATG 2280
Query: 2281 VSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNIC 2340
VSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNIC
Sbjct: 2281 VSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNIC 2340
Query: 2341 KVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNT 2400
KVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNT
Sbjct: 2341 KVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNT 2400
Query: 2401 QHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELF 2460
QHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELF
Sbjct: 2401 QHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELF 2460
Query: 2461 SSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIP 2520
SSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIP
Sbjct: 2461 SSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIP 2520
Query: 2521 ILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQ 2580
ILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQ
Sbjct: 2521 ILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQ 2580
Query: 2581 QVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLI 2640
QVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLI
Sbjct: 2581 QVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLI 2640
Query: 2641 PAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRATSTSPNSQSS 2700
PAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRATSTSPNSQSS
Sbjct: 2641 PAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRATSTSPNSQSS 2700
Query: 2701 KMNSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKA 2760
KMNSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKA
Sbjct: 2701 KMNSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKA 2760
Query: 2761 QKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTEETKS 2817
QKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTEETKS
Sbjct: 2761 QKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTEETKS 2817
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 387 bits (994), Expect = e-107
Identities = 248/540 (45%), Positives = 300/540 (55%), Gaps = 71/540 (13%)
Query: 1 MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTA--RHGLQSLGKVGISRRMPPPA 58
MS++SG + K KDGKKY++L+LF+TYKGKSLE QK RHGLQSLGKV I+RRMPPPA
Sbjct: 1 MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPA 60
Query: 59 NLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHE----EEKTPEVPPAQPKPGVAAP--- 111
NLPSLKAENKGNDPNV++VPKDGTGWASKQEQ + + T + P +QP P P
Sbjct: 61 NLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASN 120
Query: 112 ------------PEVAPAPKSW--ASNKQGGQGDGIQVNSQF----QQEFPSLQAAGDQE 153
P V KSW AS G GDG + +S ++EFP+LQAAGDQ+
Sbjct: 121 QPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQD 180
Query: 154 K--KEKETNDDNYGPGPSLRPPNVACWRDGGKAAGSPSSSDQDEKLPGQDESTAGTSEQN 211
K KE+E+ + + GPGPSLRP N WRDGG G D KL + G
Sbjct: 181 KAAKERESAEQSSGPGPSLRPQNSTTWRDGG-GRGPDELEGPDSKLHHGHDPRGGLQPS- 238
Query: 212 DILKVVEKRIACGPPQAKLNGQQAALASQYRAMMPPYMFQQYPRMTYPPLHGPM---RFP 268
GPPQ YR MMPP+M+ Y + +PP +GP R+P
Sbjct: 239 ------------GPPQ----------FPPYRGMMPPFMYPPY--LPFPPPYGPQGPYRYP 274
Query: 269 ----PSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQM 324
PS G RG GPP RPSIL LKE FD LD E D+GWAGA
Sbjct: 275 TPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKE---FDQLDQENDDGWAGAHE 331
Query: 325 EVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPS 384
EVDYTE+L FS D+E G +S +E + S+++ E E D +S+ P P
Sbjct: 332 EVDYTEKLKFS-DEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSE-PPTPK 389
Query: 385 VAKVPYGKGPSFNQ-ERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDE 443
A + P LPPP + A PP P R GP DEDE
Sbjct: 390 TAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPG--DYPDRGGPPCKPPAPEDEDE 447
Query: 444 IWKQRRRQ-QSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE 502
W+QRR+Q SEIS AVERAR+RREEEERRM+E+R+AACAEKLKRLDEK G +K+ E
Sbjct: 448 AWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAE 507
Score = 213 bits (541), Expect = 3e-54
Identities = 313/1189 (26%), Positives = 434/1189 (36%), Gaps = 268/1189 (22%)
Query: 497 KQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKE----KELEKEQEKQ 552
K P+PE+ E R++ ++ E+ E+ R + E++R Q+E+ ++L++ EK
Sbjct: 438 KPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKF 497
Query: 553 REMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVE 612
+K K E KE E EP EP P +
Sbjct: 498 GAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPET-EPEEPAQAPPAQ 556
Query: 613 KQ------------------ESENSCNKEEEPVFTRQDSNRSEKE-------ATPVVHET 647
S +S + E PV + S + TP V +
Sbjct: 557 STPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKV 616
Query: 648 EPES---GSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQP 704
EP+ G +P + ++QKSLPPRFQR QQQ+Q
Sbjct: 617 EPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQR-----------QQQEQ----------- 654
Query: 705 SSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGM 764
L + Q H G P + S P + PA PP
Sbjct: 655 ------------LLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPP---- 698
Query: 765 IPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPK 824
PPK L P +F+ + +PR+L G P P +
Sbjct: 699 -PPKALYPGALGRPPPMPPMNFDPRWMMIPPYV----DPRLLQGRPPLDFYPPGVHPSGL 753
Query: 825 ATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRP 884
E D ++ ++ A E PK A V + + + RP
Sbjct: 754 VPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKL--------AWVGDVFTATPAEPRP 805
Query: 885 HHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSA 944
T Q+A + ++ + P + S P P
Sbjct: 806 L-TSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGF--------------------PEN 844
Query: 945 GIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREE 1004
G P +EP RP P + + P P+K K ET P + R+
Sbjct: 845 GAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKE-PPKEETAQLTGPEAGRKPA 903
Query: 1005 VNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPP 1064
R V G P R+ + E P + PP P
Sbjct: 904 ---RGVGSGGQGPPPPRRESRTETRWG------------------PRPGSSRRGIPPEEP 942
Query: 1065 PQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKP-SQDTEKPLEPVSTVQVEPAVKTVN 1123
PP P PPP T+ L KP Q E P P +P +
Sbjct: 943 GAPPRRAGPIKKPPP---------PTKVEELPPKPLEQGDETPKPP------KPDPLKIT 987
Query: 1124 QQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQ 1183
+ + P +E P +S P P R E P
Sbjct: 988 KGKLGGP---KETPPNGNLS-------PAPRLRRDYSYERVGPTSC-------------- 1023
Query: 1184 GYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHT-RDYPQYRDNKPR-----AEHIPSGPLR 1237
RGRGRGEY++RGR +RG+YGGRGRG R R Y ++R + R + P P R
Sbjct: 1024 --RGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAP-R 1080
Query: 1238 QREESETRSESSDFEVVPKRRRQRGSETDTDSEIHES---ASDKDSLSKGKLPKREERPE 1294
R SETRSE S++E +PKRRRQRGSE T SE HES SDK++ P +E
Sbjct: 1081 GRTASETRSEGSEYEEIPKRRRQRGSE--TGSETHESDLAPSDKEA------PTPKEGTL 1132
Query: 1295 NKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRD 1354
+ P+ P P + R + F P+G P+RRGRG
Sbjct: 1133 TQVPLAPPPPGAPPSPAP----------ARFTARGGRVFTPRGVPSRRGRG--------- 1173
Query: 1355 PGGRPSRPSTLRRPAYRDNQWN-PRQSEVPK--PEDGEPPRRH---EQFI-----PIAAD 1403
GGRP P W+ P +S PK P PP + E+ I P+A
Sbjct: 1174 -GGRP--------PPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARG 1224
Query: 1404 KRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLR-EREAASKSNE-----VVAVPT 1457
+ ERPRR+R R +QDKPPRFRRL+ ERE A++ +E +
Sbjct: 1225 GSNGGSNVGMEDG-ERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASA 1283
Query: 1458 NGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNA 1517
G + V + K+PDLSNQN SDQANEEWETASESSDF R D++
Sbjct: 1284 PGPEEALTTVTVAPAPRRAAAKSPDLSNQN-SDQANEEWETASESSDFTSERRGDKEAPP 1342
Query: 1518 D--LNAQTVVKVG---------------ENVLPPKREIAKRSFSSQRP-VDRQNRR---- 1555
L + V G ++ ++++KRSFSSQRP ++RQNRR
Sbjct: 1343 PVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPG 1402
Query: 1556 ----------GNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAG 1594
G G GR G R ++RS P K+ R P +++P G
Sbjct: 1403 GKAGSSGSSSGGGGGGPGGRTGPG-RGDKRSWPSPKNRSRPP-EERPPG 1449
Score = 72.8 bits (177), Expect = 5e-12
Identities = 82/268 (30%), Positives = 117/268 (43%), Gaps = 47/268 (17%)
Query: 2463 SLQPYRSQPAFMQSSLSQPSVVLSGTAIH----NFPTVQHQELAKAQSGLAFQQTSNTQP 2518
SL PYRSQP ++ + PS +LSG A+ +F T+Q EL K +G P
Sbjct: 1870 SLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLY-----PP 1924
Query: 2519 IPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSA 2578
LY + S L DT LLQ R +L S+ YS +Q GQ+ F S +
Sbjct: 1925 PSFLY------SPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGF---LPSGAP 1975
Query: 2579 LQQVTVPLPASQLSLPNFGS-------TGQPLIALP--QTLQPPLQHTTPQAQAQSLSRP 2629
QQ+ +P+ SQL + NFGS PL LP LQPP P + P
Sbjct: 1976 AQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLP 2035
Query: 2630 AQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIK-----PG---TPPIAGRST 2681
+ ++PF PA + ++ +ELK F + PG TPP GRS
Sbjct: 2036 SP-ARPF----PASLGRA------ELHPVELKPFQDYQKLSSNLGGPGSSRTPP-TGRSF 2083
Query: 2682 TPTSSPFRATSTSPNSQSSKMNSIVYQK 2709
+ +S +AT ++ + +YQ+
Sbjct: 2084 SGLNSRLKATPSTYSGVFRTQRVDLYQQ 2111
Score = 57.8 bits (138), Expect = 2e-07
Identities = 90/351 (25%), Positives = 116/351 (33%), Gaps = 90/351 (25%)
Query: 1725 LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAP 1784
LPPRF ++Q + + Q PP+ P S P P TL VPA + P
Sbjct: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPT-----PVPPSPPQPVTLGAVPAPQAPP 697
Query: 1785 VPASTLAPVLASTSAPVP----------------------ASPLAPVSASASVSASVPAS 1822
P L P P+P PL S VP
Sbjct: 698 PPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRE 757
Query: 1823 TSAAAITSSS-----APA-----SAPAPTPILASV-----STPASVTILASASIPILASA 1867
S + +SS APA P P LA V +TPA L S P+ +A
Sbjct: 758 RSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS---PLRQAA 814
Query: 1868 ------LASTSAPTPAP---AASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTP 1918
+ S + P P P AS P P AP P S P P P P P
Sbjct: 815 DEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR-------FPLEEPGPRPLPWP 867
Query: 1919 --------VSAPNPAPPAPAQTQAQTHKPV--QNPLQTTSQSSKQPPPSIRLPSAQTPNG 1968
+ P P P + AQ P + P + + PPP R +T G
Sbjct: 868 PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWG 927
Query: 1969 TDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPS 2019
+S + I P+ G APP ++ GPI P PP+
Sbjct: 928 PRPGSSRRGI-PPEEPG-----------APP-------RRAGPIKKPPPPT 959
Score = 55.8 bits (133), Expect = 6e-07
Identities = 139/652 (21%), Positives = 200/652 (30%), Gaps = 118/652 (18%)
Query: 1352 GRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPK--------PEDGEPPRRHEQFIPIAAD 1403
G P RP +T R R P + E P P G P QF P
Sbjct: 194 GPGPSLRPQNSTTWRDGGGR----GPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRG- 248
Query: 1404 KRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNN 1463
PP + P Q P R P D P RF R+ + +V
Sbjct: 249 MMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLV---------- 298
Query: 1464 VAQEPVNTLGDISGNKTPDLSNQNSSDQANEE-WETASESSDFNERRERDEKKNADLNAQ 1522
EPV G S K +L + DQ N++ W A E D+ E+ + ++++
Sbjct: 299 ---EPV---GRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDG----- 347
Query: 1523 TVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKS 1582
R D + G+ R+ E R PP
Sbjct: 348 ------------------------RDSDEEGAEGH-------RDSQSASGEER--PPEAD 374
Query: 1583 GKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEK 1642
GK+G +S + + P + S+ + +PGP PK
Sbjct: 375 GKKG-----------------NSPNSEPPTPKTAWAETSRPP------ETEPGPPAPKPP 411
Query: 1643 VDALSQFDLNNYASVVIIDDH------PEVTVIEDP---QSNLNDDGFTEVVSKKQQKRL 1693
+ + N+ D P ED Q + ++ ++R
Sbjct: 412 LPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRR 471
Query: 1694 QDEERRKKEEQVIQVWNK-KNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASA 1752
++EERR +EE+ K K +EK + +L A A A A L +
Sbjct: 472 EEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAP 531
Query: 1753 PLPPSTSASVPAS-----TSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLA 1807
P PP SA P + AP PA TP P +AP S +++S ASP+
Sbjct: 532 PAPPPASAPTPETEPEEPAQAP-PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE 590
Query: 1808 PVSASAS----VSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPI 1863
P S P +T P P + P L
Sbjct: 591 PQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQ 650
Query: 1864 LASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPA--PTPVSA 1921
L +AP P P T AP + P A P +
Sbjct: 651 QQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGR 710
Query: 1922 PNPAPPAPAQTQAQTHKPVQNP--LQTTSQSSKQPP---PSIRLPSAQTPNG 1968
P P PP + P +P LQ PP PS +P ++ +G
Sbjct: 711 PPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSG 762
Score = 52.4 bits (124), Expect = 6e-06
Identities = 122/525 (23%), Positives = 174/525 (33%), Gaps = 109/525 (20%)
Query: 961 ERPEEKPKKEGFIRSSEGPKPEKVYKSKS---ETRWGPR------PSSNRREEVN----- 1006
ERP E K+G +SE P P+ + S ET GP P +R N
Sbjct: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPG 427
Query: 1007 DRPVRRSGPIKKPVLRD-------------------------MKEEREQRKEKE-----G 1036
D P R P K P D +EE E+R ++E
Sbjct: 428 DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACA 487
Query: 1037 EKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPA--PIQPQSVPPPIQPEAEKFPSTETAT 1094
EK +++ EK P+K K + PP P PA P P+ +P P P P+ ET
Sbjct: 488 EKLKRLDEKFGA-PDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPET-- 544
Query: 1095 LAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPD 1154
EP Q PA T AAP + S P
Sbjct: 545 -------------EPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEP 591
Query: 1155 SRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGH 1214
P+ KE PP +E P +G G +R +G
Sbjct: 592 QLPS--KEGPEPP----EEVPPPTTPPVPKVEPKGDGIGPTRQPPSQG------------ 633
Query: 1215 TRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHES 1274
YP+Y+ + P P +Q+E+ + + ++ + Q+GS T
Sbjct: 634 -LGYPKYQKSLP-----PRFQRQQQEQLLKQQQQHQWQ-----QHQQGSAPPTP----VP 678
Query: 1275 ASDKDSLSKGKLPKREERPENKKPVKPHSSFKPD--NHVRIDNR-LLEKPYVRDDDKAKP 1331
S ++ G +P + P K + P + +P + D R ++ PYV D +
Sbjct: 679 PSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYV--DPRLLQ 736
Query: 1332 GFLPKG-EPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEP 1390
G P P G R D GG S P PA + P P D +
Sbjct: 737 GRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTP-------PVDPKL 789
Query: 1391 PRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPP 1435
+ F A+ RP + A E + R PP PP
Sbjct: 790 AWVGDVFTATPAEPRPLTSPLR-QAADEDDKGMRSETPPVPPPPP 833
Score = 51.2 bits (121), Expect = 1e-05
Identities = 244/1293 (18%), Positives = 412/1293 (31%), Gaps = 250/1293 (19%)
Query: 1048 VKPEKTEKKDLPPP---PPPPQPPAP-IQPQS--VPPPIQPEAEK--FPSTETATLAQKP 1099
V+P+ K+ PP PPP PP P ++P+ + P QP ++ +P + + +
Sbjct: 589 VEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQ 648
Query: 1100 SQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRP-- 1157
Q E+ L+ Q + +QQ A P P+ V + P P + P
Sbjct: 649 RQQQEQLLKQQQQHQWQQ-----HQQGSAPPTPVPPSPPQPVTLGAV----PAPQAPPPP 699
Query: 1158 -------AVKKESTLPPRTYWKEARERDWFPDQGY------RGRGRGEYYSRGRSYRGSY 1204
A+ + +PP + + W Y +GR ++Y G G
Sbjct: 700 PKALYPGALGRPPPMPPMNF-----DPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLV 754
Query: 1205 GGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSE----SSDFEVVPKRRRQ 1260
R R G + ++P H P+ LR+R + F P R
Sbjct: 755 P-RERSDSGGS-------SSEPFDRHAPA-MLRERGTPPVDPKLAWVGDVFTATPAEPRP 805
Query: 1261 RGSETDTDSEIHESASDKDSLSKGKLPKREERP----------ENKKPVKPHSSFKPDNH 1310
S + ++A + D + + P P EN P P S F +
Sbjct: 806 ------LTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEP 859
Query: 1311 VRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSR--------P 1362
R L P D+ PK EP + T + G + G +P+R P
Sbjct: 860 ---GPRPLPWPPGSDEVAKIQTPPPKKEPPKEE---TAQLTGPEAGRKPARGVGSGGQGP 913
Query: 1363 STLRRPAYRDNQWNPRQSE----VPKPEDGEPPRRHEQFI----PIAADKRPPKFERKFD 1414
RR + + +W PR +P E G PPRR P ++ PPK
Sbjct: 914 PPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPK------ 967
Query: 1415 PARERPRRQRPTRP------------PRQDKP-------PRFRRLREREAASKSN----- 1450
P + +P +P P++ P PR RR E ++
Sbjct: 968 PLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRG 1027
Query: 1451 ------------EVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWET 1498
G + + GD N + + ET
Sbjct: 1028 RGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASET 1087
Query: 1499 ASESSDFNE----RRERDEKKNADLNAQTVVKVGENVLPPK------------------- 1535
SE S++ E RR+R + ++ + + + PK
Sbjct: 1088 RSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPS 1147
Query: 1536 ----REIAK--RSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSG-------PPSKS 1582
R A+ R F+ + R+ R G PP+ +S P PPSK
Sbjct: 1148 PAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKE 1207
Query: 1583 GKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEK 1642
+ P NG S G+ +G + + ++++ P + +E+
Sbjct: 1208 PLKEKLIPGPLSPVARGGSNGGS---NVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER 1264
Query: 1643 VDALSQFDLNNYASVVIIDDHPE-----VTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEE 1697
+A + ++ PE VTV P+ +K Q+ +
Sbjct: 1265 ENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPR---------RAAAKSPDLSNQNSD 1315
Query: 1698 RRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPS 1757
+ +E + + + +G + PP +A G +VP + SA
Sbjct: 1316 QANEEWETASESSDFTSERRGDKEAP--PPVLLTPKAVGTPGGGGGGAVPGI-SAMSRGD 1372
Query: 1758 TSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSA 1817
S + + + P P A S+S P
Sbjct: 1373 LSQRAKDLSKRSFSSQRPGMERQNRRPGPGGK-AGSSGSSSGGGGGGPGGRTGPGRGDKR 1431
Query: 1818 SVPASTSAAAITSSSAPA-SAPAPTPILASV--------STPASVTILASASIPILASAL 1868
S P+ + + P P P P ++V S PA + ++ L+S
Sbjct: 1432 SWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGI----QQALAQLSSRQ 1487
Query: 1869 ASTSAP----------TPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTP 1918
S +AP AP SP P P S ++ TP
Sbjct: 1488 GSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTP 1547
Query: 1919 VSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSI 1978
+ +P P + + KP Q PPP P G A +
Sbjct: 1548 RDSAGVSPFPPKRRERPPRKP------ELLQEESLPPPHSSGFLGSKPEGPGPQAESRDT 1601
Query: 1979 QTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEG 2038
T LT +W+ L+ + + +P S+ W +PL+ F +E
Sbjct: 1602 GTE----ALTPHIWNR-------LHTATSR----KSYRPSSMEPWMEPLSPFEDVAGTEM 1646
Query: 2039 AKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKA 2098
+++ +SG+++ D+ P S + + + + K P P GP +
Sbjct: 1647 SQS--DSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGS 1704
Query: 2099 Q--KLPDLSPVENKEHK--------PGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVR 2148
+ + P +P + + PGPIG ERS + + + + P + P P
Sbjct: 1705 EPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGP-PVQFG 1763
Query: 2149 STDP------VTTKETKAVSEMSTEIGTMISVS 2175
++D V KA E++ + I VS
Sbjct: 1764 TSDKDSDLRLVVGDSLKAEKELTASVTEAIPVS 1796
Score = 49.7 bits (117), Expect = 4e-05
Identities = 218/1050 (20%), Positives = 328/1050 (31%), Gaps = 190/1050 (18%)
Query: 1050 PEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEP 1109
P K+ PP P P P++ + +P P+ P A + + + + +
Sbjct: 1188 PAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGR 1247
Query: 1110 VSTVQVEPAVKTVNQQTMAAPVVKEEKQ----------PEKVISKDLVIERPRPDSR--P 1157
P + + Q+ A E K PE+ ++ V PR + P
Sbjct: 1248 AQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSP 1307
Query: 1158 AVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRD 1217
+ +++ W+ A E F + RG E + G G GG G
Sbjct: 1308 DLSNQNSDQANEEWETASESSDFTSER---RGDKEAPPPVLLTPKAVGTPGGGGGGAV-- 1362
Query: 1218 YPQYRDNKPRAEHIPSGPLRQR-EESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS 1276
P + G L QR ++ RS SS + ++ R+ G S S
Sbjct: 1363 --------PGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGG 1414
Query: 1277 --------------DKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHV--RIDNRLLEK 1320
DK S K R PE + P P P + R+D +
Sbjct: 1415 GGGGPGGRTGPGRGDKRSWPSPK--NRSRPPEERPPGLPLPPPPPSSSAVFRLDQVI--- 1469
Query: 1321 PYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQS 1380
+ P + + R G+ G P +P P + P+ R
Sbjct: 1470 -------HSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPR--------- 1513
Query: 1381 EVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARE---RPRRQR---PTRPPRQDKP 1434
PP R+E + P FE R PR P P R+++P
Sbjct: 1514 ---------PPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERP 1564
Query: 1435 PRFRRLREREAASK--SNEVVAVPTNGTVNNVAQEPVNTLG---DISGNKTPDLSNQNSS 1489
PR L + E+ S+ + G T I S ++
Sbjct: 1565 PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYR 1624
Query: 1490 DQANEEW-ETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRP 1548
+ E W E S D DL+ + V G SQR
Sbjct: 1625 PSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGP--------------CSQRS 1670
Query: 1549 VDRQNRRGN-NGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAH 1607
+G GPPK S GPP R P PA G +
Sbjct: 1671 SPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRP---PPAPHDG----DRKELP 1723
Query: 1608 HQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVV--IIDDH-- 1663
++ +P G T + E PGP +P + QF ++ S + ++ D
Sbjct: 1724 REQPLPPGPIGTERSQRTDRGTE---PGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLK 1780
Query: 1664 ----------------------PEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKK 1701
P +PQS D G +RL E
Sbjct: 1781 AEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGS 1840
Query: 1702 EEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPP-LASAPLPPSTSA 1760
++ G + S+L P + G S P L P PPS
Sbjct: 1841 A-------GPSSSQISGGAMDSQLHPNSGGFRP-GTPSLHPYRSQPLYLPPGPAPPSALL 1892
Query: 1761 SVPASTS-----APLPAT-LTPVPAS-TSAPVPASTLAPVLASTSAPVPASPLAPVSASA 1813
S A + + AT L +PA P P+ +P A +P+P + L V
Sbjct: 1893 SGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSP--AFCPSPLPDTSLLQVRQDL 1950
Query: 1814 SVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSA 1873
+ ++ S P+ APA +L V + + ++ S+P A
Sbjct: 1951 PSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDS--QLPVVNFGSLP---------PA 1999
Query: 1874 PTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQT- 1932
P PAP P+ P PA P P+ A P PAP P+PA P PA
Sbjct: 2000 PPPAPP------PLSLLPVGPALQP-------PSLAVRPPPAPATRVLPSPARPFPASLG 2046
Query: 1933 QAQTHKPVQNPLQTTSQSSKQ--PPPSIRLPSAQTPNGTDYVASGKSIQ-TPQSHG---- 1985
+A+ H P Q + S P S R P P G + ++ TP ++
Sbjct: 2047 RAELHPVELKPFQDYQKLSSNLGGPGSSRTP----PTGRSFSGLNSRLKATPSTYSGVFR 2102
Query: 1986 TLTAELWDNKVAPPAVLNDISKKLGPISPP 2015
T +L+ + +PP L I K PP
Sbjct: 2103 TQRVDLY-QQASPPDALRWIPKPWERTGPP 2131
Score = 44.7 bits (104), Expect = 0.001
Identities = 142/620 (22%), Positives = 205/620 (33%), Gaps = 110/620 (17%)
Query: 1376 NPRQSEVPKPEDGEPPRRHEQFIPIAADK---RPPKFERKFDPARERPRRQRPTRPPRQD 1432
+P S VPK G ++ EQ P ++D +PP+ + PA + P +P RPP
Sbjct: 73 DPNVSLVPKDGTGWASKQ-EQSDPKSSDASTAQPPESQPL--PASQTPASNQPKRPPAA- 128
Query: 1433 KPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQA 1492
P L S + V +G + + L S + P L D+A
Sbjct: 129 --PENTPLVPSGVKSWAQASVTHGAHGDGGRAS----SLLSRFSREEFPTLQAAGDQDKA 182
Query: 1493 NEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQ 1552
+E E+A +SS L P+ R + P + +
Sbjct: 183 AKERESAEQSSGPGPS-----------------------LRPQNSTTWRDGGGRGPDELE 219
Query: 1553 ---NRRGNNGPPKSGRNFSGPRN---ERRSGPPSKSGKRGPFDDQ--PAGTTGVDLINGS 1604
++ + P+ G SGP R PP PF P G +G
Sbjct: 220 GPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGP 279
Query: 1605 SAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHP 1664
S + P G+G + +P P KE D L +FD +D
Sbjct: 280 SRFPRVAGPRGSGPP-------MRLVEPVGRPSILKE--DNLKEFDQ--------LDQE- 321
Query: 1665 EVTVIEDPQSNLNDDGFT---EVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQ 1721
NDDG+ E V ++ + DEE + ++ ++ + + G +
Sbjct: 322 ------------NDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEER 369
Query: 1722 TSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPAST 1781
PP +A G ++ S S PP P S P T PA P+P
Sbjct: 370 ----PP-----EADG-KKGNSPNSEPP---TPKTAWAETSRPPETEPGPPAPKPPLPPPH 416
Query: 1782 SAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPT 1841
P P P P AP + S+S ++ A
Sbjct: 417 RGPAGNWGPPGDYPDRGGP-PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEE 475
Query: 1842 PILASVSTPASVTILASASIPILAS---ALASTSAPTPAPAASSPAAPVITAPTIPASAP 1898
+ A L A A +AP AP S+PA P P +P P
Sbjct: 476 RRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAP--STPAPP----PAVPKELP 529
Query: 1899 TASVPLAPASASAPAPAPTPVSAPNPAPPA---PAQTQAQTHKPVQNPLQTTSQSS---K 1952
P AP ASAP P P P APPA P A V T+S SS +
Sbjct: 530 ---APPAPPPASAPTPETEP-EEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFE 585
Query: 1953 QPPPSIRLPSAQTPNGTDYV 1972
P +LPS + P + V
Sbjct: 586 ASPVEPQLPSKEGPEPPEEV 605
Score = 39.3 bits (90), Expect = 0.056
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 7/135 (5%)
Query: 1890 APTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQT-QAQTHKPVQ-NPLQTT 1947
AP A A+ P AP++ + P P + AP PPA A T + + +P Q P Q+T
Sbjct: 499 APDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQST 558
Query: 1948 SQSSKQPPPSIRLPSAQTPNGT--DYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDI 2005
P++ T + + + AS Q P G E PP + +
Sbjct: 559 PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPP--VPKV 616
Query: 2006 SKKLGPISPP-QPPS 2019
K I P QPPS
Sbjct: 617 EPKGDGIGPTRQPPS 631
Score = 35.0 bits (79), Expect = 1.0
Identities = 65/315 (20%), Positives = 108/315 (34%), Gaps = 40/315 (12%)
Query: 1870 STSAPTPAPAASSPAAPVITAPTIPASAPTASVP-LAPASASAPAPAPTPVSAPNPAPPA 1928
++ PTP A + + P T P PA P P PA P P PPA
Sbjct: 382 NSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPA 441
Query: 1929 P-----------AQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTD--YVASG 1975
P Q+ ++ V+ + + ++ R A+ D + A
Sbjct: 442 PEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPD 501
Query: 1976 KSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPS 2035
K ++ + PPAV ++ +PP PP SA P T
Sbjct: 502 KRLKAEPAAPPAAP---STPAPPPAVPKELP------APPAPPPASA-PTPETEPEEPAQ 551
Query: 2036 SEGAKNGQESGLEIGTDTIQFGAPASNGNEN--EVVPVLSEKSADKIPEPKEQ------- 2086
+ A++ G+ + G S+ + E PV + + + PEP E+
Sbjct: 552 APPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTP 611
Query: 2087 --RQKQPRAGPIKAQKLPDLSPV-ENKEHKPGPIGKERSLKNRKVKDAQQVE----PEGQ 2139
+ +P+ I + P + K K P +R + + +K QQ + +G
Sbjct: 612 PVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGS 671
Query: 2140 EKPSPATVRSTDPVT 2154
P+P PVT
Sbjct: 672 APPTPVPPSPPQPVT 686
Score = 32.0 bits (71), Expect = 8.9
Identities = 52/255 (20%), Positives = 86/255 (33%), Gaps = 26/255 (10%)
Query: 185 AGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACG---PPQAKLNGQQAALASQY 241
AG+ D EKL DE S++ + + A G PP+A +G++ +
Sbjct: 327 AGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEA--DGKKGNSPNSE 384
Query: 242 RAMMPPYMFQQYPRMTYPPLH--GPMRFPPSLSETNKGLRGR-GPPPSWASEPERPSILS 298
PP + + PP GP P L ++G G GPP + P
Sbjct: 385 ----PPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPP 440
Query: 299 ASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKAS 358
A E + DE W Q + +++ + + + +E +++ A
Sbjct: 441 APE------------DEDEAWR--QRRKQSSSEISLAVERARRRREEEERRMQEERRAAC 486
Query: 359 ENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHP 418
+ + + K PA P A P+ +E PP + P
Sbjct: 487 AEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEP 546
Query: 419 PPDRQAVPGRPGPFP 433
QA P + P P
Sbjct: 547 EEPAQAPPAQSTPTP 561
>gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]
Length = 2229
Score = 362 bits (930), Expect = 2e-99
Identities = 425/1450 (29%), Positives = 632/1450 (43%), Gaps = 232/1450 (16%)
Query: 445 WKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEI 504
W RR++Q +S+A KR EE + E A A ++ R + QP P ++
Sbjct: 407 WDPRRQRQLSMSSADSADAKRTREEGKDWAE---AVGASRVVRKAP-----DPQPPPRKL 458
Query: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM-EKERKQEK 563
+ ++ ++Q E + +K RQ+ + E+ + E+ R+ E+E ++ +
Sbjct: 459 HGWAPGPDYQKSSMGSMFRQQSIEDKEDKPPPRQKFIQSEMSEAVERARKRREEEERRAR 518
Query: 564 EKELERQKEKEKEL-QKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNK 622
E+ L K K+L QK K+ K E K+ EK P P+ E QE+ + +K
Sbjct: 519 EERLAACAAKLKQLDQKCKQARKAGEARKQAEKEV----PWSPSAEK-ASPQENGPAVHK 573
Query: 623 EEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQ---FQKSLPPRFQRQQ 679
P F Q++ + E P V +S S A +G Q +QKSLPPRFQRQQ
Sbjct: 574 GS-PEFPAQETPTTFPEEAPTVSPAVAQSNSSEEEAREAGSPAQEFKYQKSLPPRFQRQQ 632
Query: 680 EQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLM 739
+Q +Q+Q + Q QP V PPP P HPQ L GFDPRW+M
Sbjct: 633 QQQQQEQLYKMQHW---------QP----VYPPPSHPQRTFYPHHPQML---GFDPRWMM 676
Query: 740 MQSYMDPRMMSGRPAMDIPP--IHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHA 797
M SYMDPR+ R +D P +HP + KP+M ++ + G+ SE ++ ++
Sbjct: 677 MPSYMDPRITPTRTPVDFYPSALHPSGLM-KPMMPQESLNGTGCRSED-QNCVPPLQERK 734
Query: 798 ISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAH 857
++ + +W + Y + + P + + + + + E +A + A
Sbjct: 735 VTPIDSPPVWSPEGYMALQSKGYPLPHP-KSSDTLAMDMRVRNESSFSASLGRAGGVSA- 792
Query: 858 PKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAP--DQKTLSAPQEERISAV 915
+ D E E + F ++ D +C + Q+ L PQE A
Sbjct: 793 -QRDLFEERGEEYLSAFDKKAQADF----------DSCISSQRIGQELLFPPQENVQDAG 841
Query: 916 ESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRS 975
+ PDE++ E + D+ +ER E P++
Sbjct: 842 APGGHTQNLRCSPLEPDFVPDEKKPECGSWDVSHQPETADTAHGVER--ETPREGTAFNI 899
Query: 976 SEGPK---PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRK 1032
S K P K S+ E PR SS++ E R RRSGPIKKPVL+ +K E K
Sbjct: 900 SSWDKNGSPNKQPSSEPEWTPEPRSSSSQHPEQTGR-TRRSGPIKKPVLKALKVED---K 955
Query: 1033 EKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTET 1092
EKE EK +K E E+ + E E+ P+ E
Sbjct: 956 EKELEK---------IKQELGEESTR---------------------LAKEKEQSPTAE- 984
Query: 1093 ATLAQKPSQDTEKPLEPVSTVQVE---PAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIE 1149
+ ++ + L ST +E P T ++ A +EE++P+K
Sbjct: 985 ----KDEDEENDASLANSSTTTLEDKGPGHATFGRE---ATKFEEEEKPDKAW------- 1030
Query: 1150 RPRPDSRPAVKKESTLPP--RTYWKEARERDWFPDQGY-RGRGRG--EYYSRGRSYRGSY 1204
++RP ++ S +PP R W E F +G RGRGRG E+ RGR G+
Sbjct: 1031 ----EARPP-RESSDVPPMKRNNWIFIDEEQAFGVRGQARGRGRGFREFTFRGRPAGGNG 1085
Query: 1205 GGRGRGG-------------RGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDF 1251
G GG G R ++ R E P R+R SET SE S++
Sbjct: 1086 SGLCGGGVLGARSIYCSSQRSGRGRGLREFA----RPEDCPRAKPRRRVASETHSEGSEY 1141
Query: 1252 EVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNH- 1310
E +PKRRRQRGSE + + E ++ +L KG R+ NK + HS +
Sbjct: 1142 EELPKRRRQRGSENGNEGSLLER--EESTLKKGDC--RDSWRSNKGCSEDHSGLDAKSRG 1197
Query: 1311 VRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGR---------GGTFRRGGRDPGGRPSR 1361
R R L P + + + F+ K P + + G + G R P R
Sbjct: 1198 PRAFGRALP-PRLSNCGYGRRTFVSKESPHWQSKSPGSSWQEYGPSDTCGSRRPTDRDYV 1256
Query: 1362 PSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPR 1421
P + R P + + R E + ED + E AD + A RP
Sbjct: 1257 PDSYRHP----DAFGGRGFEDSRAEDKRSFFQDEH----VADS---------ENAENRPF 1299
Query: 1422 RQRPTRPPRQDKPPRFRRLR-EREAAS-----KSNEVVAVPTNGTVNNVAQEPVNTLGDI 1475
R+R RPPRQDKPPRFRRLR ERE+ + ++A G + + T+G
Sbjct: 1300 RRR--RPPRQDKPPRFRRLRQERESLGLWGPEEEPHLLAGQWPGRPKLCSGDKSGTVG-- 1355
Query: 1476 SGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPK 1535
++P+LS QNSSD ANEEWETASESSDF+ERRER E ++ ++Q + L K
Sbjct: 1356 --RRSPELSYQNSSDHANEEWETASESSDFSERRERREGPGSEPDSQVDGGLSGASLGEK 1413
Query: 1536 REIAKRSFSSQRP-VDRQNRRGNNG-----PPKSGRNFSGPRNE-RRSGPPSKSGKRGPF 1588
+E+AKRSFSSQRP VDRQ+R+ G P + G + PR E +++G P K KR P
Sbjct: 1414 KELAKRSFSSQRPVVDRQSRKLEPGGFGEKPVRPGGGDTSPRYESQQNGTPLKV-KRSPD 1472
Query: 1589 DDQPAGTTGVDLINGSS-------AHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKE 1641
+ P G +G +G S AH +P + +K K++ K P+ G E
Sbjct: 1473 EALPGGLSGCSSGSGHSPYALERAAHASADLPEASSKKAEKEA---KLAAPRAG-----E 1524
Query: 1642 KVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKK 1701
+ +A+ QFDL NY S II++ E ++ +GF EV++KK Q+RL +EERRKK
Sbjct: 1525 QGEAMKQFDL-NYGS-AIIENCGSSPGEESEVGSMVGEGFIEVLTKK-QRRLLEEERRKK 1581
Query: 1702 EEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSAS 1761
EQ +QV KGR +S++PPRFAKKQ + Q +VP S
Sbjct: 1582 -EQAVQV------PVKGRGLSSRIPPRFAKKQ-NNLCLEQGDVTVP-------GSSLGTE 1626
Query: 1762 VPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPA 1821
+ S+S LP AP S V A +S ++ S+ + A
Sbjct: 1627 IWESSSQALP---------VQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSGVDLSA 1677
Query: 1822 STSAAAITSS 1831
+ ++ TSS
Sbjct: 1678 ESRESSATSS 1687
Score = 299 bits (765), Expect = 3e-80
Identities = 238/667 (35%), Positives = 323/667 (48%), Gaps = 101/667 (15%)
Query: 1 MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTA--RHGLQSLGKVGISRRMPPP 57
MS++ GQ TK KDGK KY+TLSLF+ YKGKS++ +++ RHGLQSLGKV +RRMPPP
Sbjct: 1 MSDRLGQITKGKDGKSKYSTLSLFDKYKGKSVDAIRSSVIPRHGLQSLGKVAAARRMPPP 60
Query: 58 ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKT----PEVPPAQPKPGVAA--- 110
ANLPSLK+ENKGNDPN+ IVPKDGTGWA+KQ+Q + + + + P + P+PG+
Sbjct: 61 ANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQQDPKSSSATASQPPESLPQPGLQKSVS 120
Query: 111 -------------PPEVAPAPKSWA--SNKQGGQGDGIQVNSQF----QQEFPSLQAAGD 151
V PKSWA + K G G++ +S+ +EFP+L+AAG
Sbjct: 121 NLQKPTQSISQENTNSVPGGPKSWAQLNGKPVGHEGGLRGSSRLLSFSPEEFPTLKAAGG 180
Query: 152 QEK--KEKETNDDNYGPGPSLRPPNVACWRD-GGKAAGSPSSSDQDEKLPGQDESTAGTS 208
Q+K KEK D +YGPGPSLRP NV WR+ GG+ S +S G S+ G
Sbjct: 181 QDKAGKEKGVLDLSYGPGPSLRPQNVTSWREGGGRHIISATSLSTSPTELGSRNSSTGDG 240
Query: 209 EQNDILKVVEKRIACGPPQAKLNGQQAALAS-----QYRAMMPPYMFQ----------QY 253
+ K + P Q G + + Y M+P +M +
Sbjct: 241 APSSACTSDSKDPSLRPAQPVRKGASQFMGNVYHPPTYHDMLPAFMCSPKSSENQGTVER 300
Query: 254 PRMTYPPLHGPMRFP--------PSLSETNKGL-RGRGPPPSWASEPERPSILSASELKE 304
P L R P E GL R P RP+I++A LK
Sbjct: 301 GSFPLPQLRLEPRVPFRQFQMNDQDGKENRLGLSRPLRPLRQLVERAPRPTIINAENLKG 360
Query: 305 LDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQ----GSNSPKENN----SEDQGSK 356
L D+LDA+AD+GWAG EVDY+E+L FSDD+E+ PK N+ + Q S
Sbjct: 361 L---DDLDADADDGWAGLHEEVDYSEKLKFSDDEEEEEVVKDGRPKWNSWDPRRQRQLSM 417
Query: 357 ASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQ 416
+S ++ + K T E + + + A V K P + PPP+ L
Sbjct: 418 SSADSADAKRTREEGKDWAEA-VGASRVVRKAPDPQ---------------PPPRKLHGW 461
Query: 417 HPPPDRQAVPGRPGPFPSKQQVAD-EDEIWKQRRRQQSEISAAVERARKRREEEERRMEE 475
P PD Q G +Q + D ED+ +++ QSE+S AVERARKRREEEERR E
Sbjct: 462 APGPDYQ--KSSMGSMFRQQSIEDKEDKPPPRQKFIQSEMSEAVERARKRREEEERRARE 519
Query: 476 QRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDR 535
+R AACA KLK+LD+K KQ ++ EKE EK QE K
Sbjct: 520 ERLAACAAKLKQLDQKC----KQARKAGEARKQAEKEVPWSPSAEKASPQENGPAVHKGS 575
Query: 536 ER--QQEKEKELEKE---------QEKQREMEKERKQEKEKELERQKEKEKELQKMKEQE 584
QE +E Q E E +E + QK Q+ ++Q+
Sbjct: 576 PEFPAQETPTTFPEEAPTVSPAVAQSNSSEEEAREAGSPAQEFKYQKSLPPRFQRQQQQQ 635
Query: 585 KECELEK 591
++ +L K
Sbjct: 636 QQEQLYK 642
Score = 243 bits (620), Expect = 2e-63
Identities = 256/901 (28%), Positives = 378/901 (41%), Gaps = 261/901 (28%)
Query: 1931 QTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAE 1990
+ + + + VQ P++ SS+ PP + + D G S+ T E
Sbjct: 1576 EERRKKEQAVQVPVKGRGLSSRIPPRFAKKQNNLCLEQGDVTVPGSSLGT---------E 1626
Query: 1991 LWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSS---EGAKNGQ-ESG 2046
+W++ S+ L P Q P+ +W K +T+F S + +G K+ Q +SG
Sbjct: 1627 IWESS----------SQAL----PVQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSG 1672
Query: 2047 LEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSP 2106
+++ ++ + A +S + E S + EPK K+ P + QK +
Sbjct: 1673 VDLSAESRESSATSSQRSSPYGTLKPEEMSGPGLAEPKADSHKEQAPKPSE-QKDSEQGS 1731
Query: 2107 VENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMST 2166
++KEH+PGPIG ERSLKNRK EG E+ A V V+ +
Sbjct: 1732 GQSKEHRPGPIGNERSLKNRKGS-------EGAERLQGAVV-----------PPVNGVEI 1773
Query: 2167 EIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPK 2226
+ +++ V E+G + K+S D++ P S + K++D L +N L ++P+ +
Sbjct: 1774 HVDSVLPVPPIEFGVSPKDS--DFSLPPGSASGPTGSPVVKLQDALASNAGLTQSIPILR 1831
Query: 2227 RET-IQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSP---VTSTAPPIATGVS 2282
R+ IQ++ L+ + T LT KMESARKAWENSP++ E+ SP + PP + G S
Sbjct: 1832 RDHHIQRAIGLSPMSFPTADLTLKMESARKAWENSPSLPEQSSPGGAGSGIQPPSSVGAS 1891
Query: 2283 SSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKV 2342
S NY+SF SMP +PVASV P+AS+ G+
Sbjct: 1892 SG------VNYSSFGGVSMPPMPVASVAPSASMPGS------------------------ 1921
Query: 2343 KPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQH 2402
L L SQ +P I QQQ Y +AA QIP
Sbjct: 1922 ---HLPPLYLDGHVFASQPRLVPQTIPQQQS----YQQAAAAQQIP-------------- 1960
Query: 2403 ARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSS 2462
+S TS+Q QAQL L G VSQ+QE+F S
Sbjct: 1961 -----------------ISLHTSLQA-------------QAQLGLRGGLPVSQSQEIF-S 1989
Query: 2463 SLQPYRSQPAFMQSSLSQPSVVL--SGTAI----HNFPTVQHQELAKAQSGLAFQQTSNT 2516
SLQP+RSQ +M SLS PS ++ GTA+ FP +Q E+ K QSG +Q S
Sbjct: 1990 SLQPFRSQ-VYMHPSLSPPSTMILSGGTALKPPYSAFPGMQPLEMVKPQSGSPYQPMSGN 2048
Query: 2517 QPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSP 2576
Q ++YE QL QA+GLG SQ++D
Sbjct: 2049 Q--ALVYEGQLSQAAGLGASQMLD------------------------------------ 2070
Query: 2577 SALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPF 2636
S L Q+T+P LP +GS QPLI LPQ++Q P Q+ S+ P
Sbjct: 2071 SQLPQLTMP-------LPRYGSGQQPLI-LPQSIQ------LPPGQSLSVGAP------- 2109
Query: 2637 RGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRATSTSPN 2696
R + P G+Q ++ T+ + S+ME+K F D K P P+ +R +S SP+
Sbjct: 2110 RRIPPPGSQPPVLNTSREPSQMEMKGFHFA-DSKQNVP---SGGPVPSPQTYRPSSASPS 2165
Query: 2697 SQSSKMNSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIG 2756
+ S S V Q + QAKQR + + +G
Sbjct: 2166 GKPS--GSAVNMGSVQG-------------HYVQQAKQRVD-------------EKPSLG 2197
Query: 2757 GGKAQKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTEETK 2816
K Q+ APS A++ RTG IKP+A+K EE+K
Sbjct: 2198 AVKLQE-----------------------------APSAASQMKRTGAIKPRAVKVEESK 2228
Query: 2817 S 2817
+
Sbjct: 2229 A 2229
Score = 32.3 bits (72), Expect = 6.8
Identities = 35/111 (31%), Positives = 48/111 (43%), Gaps = 9/111 (8%)
Query: 43 QSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPPA 102
QSL VG RR+PPP + P + N +P+ + G +A +Q+ P P
Sbjct: 2102 QSLS-VGAPRRIPPPGSQPPVL--NTSREPSQ--MEMKGFHFAD-SKQNVPSGGPVPSPQ 2155
Query: 103 QPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQE 153
+P A+P + P A N QG +Q Q E PSL A QE
Sbjct: 2156 TYRPSSASP---SGKPSGSAVNMGSVQGHYVQQAKQRVDEKPSLGAVKLQE 2203
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 139 bits (351), Expect = 3e-32
Identities = 424/2237 (18%), Positives = 759/2237 (33%), Gaps = 333/2237 (14%)
Query: 346 KENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSH 405
+ + + G S N + + + +S S+ PA G+ S R S
Sbjct: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATR-------GRSRSRTPARRGRSR 585
Query: 406 LPPPPKLLAQQHPPPDRQA---VPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERA 462
P + ++ P R++ P R G S+ RR+ S A
Sbjct: 586 SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG 645
Query: 463 RKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKE 522
R R RR + + R + P+ R R R R +
Sbjct: 646 RSRSRTPARRGRSRSRTPARRGRSR--------SRTPARRSGRSRSRTPARRGRS---RS 694
Query: 523 QEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMK- 581
+ R + R + R+ + + + + + + + + + E++K +
Sbjct: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754
Query: 582 EQEKECELEKEREKLEEKIEPRE--------PNLEPMVEKQESENSCNKEEEPVFTRQDS 633
+ L R K + ++ R P + + S + ++ + T
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814
Query: 634 NRSEKEATPVVHETEPE----SGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ 689
+RS P P S S P P V SG + P+ Q +++ +
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
Query: 690 QQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMM 749
L PS+ S S PP + P Q + S P+ +++ + PR
Sbjct: 875 SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSR---SSSPQPK---VKAIISPRQR 928
Query: 750 SGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSES-----FEHIARSARDHAISLSEPR 804
S + P + + RR + ++ ES + H S+ D + P
Sbjct: 929 SHSGSSSPSP---SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPP 985
Query: 805 MLWGS---DPYPHAEPQQATTPKATEEPEDVRSEAALDQ--EQITAAYSVEHNQLEAHPK 859
S PYP + Q P + E + D + + S+ + P
Sbjct: 986 RQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP 1045
Query: 860 ADFIRESSEAQVQKFLSRSVEDVR-----PHHTDANNQSACFEAPDQKTLSAPQEERISA 914
+ S Q+ K S++ D R P ++++S ++ Q + + S
Sbjct: 1046 GESYFGVSSLQL-KGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSP 1104
Query: 915 VESQPSRKR--------SVSHGSNHTQKPDEQRSEP-SAGIPKVTSRCIDSKEPIERPEE 965
V SR S S P++ R + S+ P V S + + +E E
Sbjct: 1105 VTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAES 1164
Query: 966 KPK----------------KEGFIRSSEGPKPEKVYKSKSETRWGPR------------- 996
K K K+ F +PE K R PR
Sbjct: 1165 KEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKE 1224
Query: 997 -----PSSNRREE---VNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVV 1048
P+S++ EE V ++ +G I + ++KE E E E+ + +
Sbjct: 1225 QNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTL 1284
Query: 1049 KPEKT----EKKDLPP-----------PPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETA 1093
++ E ++P P +P++ S P++ TE
Sbjct: 1285 DQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMN 1344
Query: 1094 T-LAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKV----ISKDLVI 1148
T + + +D P ++ ++ +P++ Q T ++ E P+ V +S + I
Sbjct: 1345 TGFSSEVKEDLNGPF--LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSI 1402
Query: 1149 ERPRPDSRPAV--KKESTLPPRTYWKEARERDWFPDQGYR-GRGRGEYYSRGRSYRGSYG 1205
P D+ P ++ S+ K+ R P + R G G G R S
Sbjct: 1403 SSPVLDAVPRTPSRERSSSASSPEMKDGLPRT--PSRRSRSGSSPGLRDGSGTPSRHSLS 1460
Query: 1206 GRGRGGRGHTRDYPQYR---DNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRG 1262
G G + R + R D+ P + +P P R R S + E ++ + P+R R G
Sbjct: 1461 GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTP-RPRSRSPSSPELNNKCLTPQRERS-G 1518
Query: 1263 SETDTDS-----------------------------EIHESASDKDSLSKGKLPKREERP 1293
SE+ D E ES S DS +K + P R+
Sbjct: 1519 SESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSR 1578
Query: 1294 ENKKP-VKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKP----GFLPKGEPT-------- 1340
P V S P +R P V+D +A P G EP
Sbjct: 1579 SGSSPEVDSKSRLSPRR-----SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALP 1633
Query: 1341 RRGRGGTFRRG-GRDPGGRPSRPSTLRRPAY-RDNQWNPRQSEVPKPEDGEPPRRHEQFI 1398
RR R G+ +G G P G S S+ P R + R S PK + PPRR
Sbjct: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRR---- 1689
Query: 1399 PIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRL--------REREAASKSN 1450
+ + P+ RK +R R R + R PPR RR E+ +S+
Sbjct: 1690 ---SSRSSPELTRKARLSR-RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR 1745
Query: 1451 EVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRE 1510
+ P T + + P + +++ + + + + S SS RR
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDR----SGSSQSTSRRR 1801
Query: 1511 RDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGP 1570
+ + + + + G + P R+ + R+ S + RRG + P + R S
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS-------RRRRGRSRTPPTSRKRS-- 1852
Query: 1571 RNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKRE 1630
R+ P +S R + LI+ + + P + S+ S ++R
Sbjct: 1853 RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS-PVSRRRSRSRTSVTRRRS 1911
Query: 1631 DPKPGP---KKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSK 1687
+ P ++ + + +++ + + +S V +
Sbjct: 1912 RSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT---PPVTRR 1968
Query: 1688 KQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVP 1747
+ + R RR+ + V +++ RS+TS + R ++ + + + + +S + P
Sbjct: 1969 RSRSRTSPITRRRSRSRTSPVTRRRS-----RSRTSPVTRRRSRSRTSPVTRRRSRSRTP 2023
Query: 1748 PL------ASAPLPP------STSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLA 1795
P + PL P + ++ + + P T + T +P + +
Sbjct: 2024 PAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGS 2083
Query: 1796 STSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAP---------TPILAS 1846
S+ A+P P + + S S + P + +++ ++ S P+ +P P L S
Sbjct: 2084 SSDRSRSATP--PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGS 2141
Query: 1847 VSTPASVTILASASI----------------------PILASALASTSAPTPAPAASSPA 1884
TP SV A S+ +A AL + S T P S A
Sbjct: 2142 SRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA 2201
Query: 1885 APVITAPT-IPASAPTASVPLAPAS------ASAPAPAPTPVSAPNPAPPAPAQTQAQTH 1937
A + + +PA P S+ APA+ +A A A SA PA P
Sbjct: 2202 AGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRT 2261
Query: 1938 KPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVA 1997
+ S + P ++ L +TP A ++ ++ L A
Sbjct: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTP-----TAPAVNLAGARTPAALAALSLTGSGT 2316
Query: 1998 PPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFG 2057
PP N S PQ P+ + P ++ +AP + G+ T
Sbjct: 2317 PPTAANYPSSS----RTPQAPASANLVGPRSAHATAPVNIA-----------GSRTAAAL 2361
Query: 2058 APASNGNENEVVPVLS--EKSADKIPEPKEQRQKQPRAGPI---KAQKLPDLSPVENK-- 2110
APAS + P LS ++ ++P +R + P+ + P +P +++
Sbjct: 2362 APASL-TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMT 2420
Query: 2111 -EHKPGPIGKERSLKNRKVKDAQQVEPEGQEKP-SPATVRSTDP---VTTKETKAVSEMS 2165
E P P + +Q + P Q++P SP +D + + T S
Sbjct: 2421 SERAPSPSSRMGQ------APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS 2474
Query: 2166 TEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLP 2225
G + + +S+ N SV P S + A+ + L P
Sbjct: 2475 LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALA------ALQPAK 2528
Query: 2226 KRETIQQSSSLTSVPPTTFSLTFKMESARKAWENS--------PNVREKGSPVTSTAPPI 2277
+R + SSS +S ++ S + S+ + +S P V K P + AP
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588
Query: 2278 ATGVSSSAS-GPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
A P+ S SS+S +S + ++S S + + ++SS S+ S+++S
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 2337 PNICKVKPQQLQTSSLP 2353
P+ K PQ L + P
Sbjct: 2649 PSPAKPGPQALPKPASP 2665
Score = 103 bits (257), Expect = 2e-21
Identities = 341/1645 (20%), Positives = 565/1645 (34%), Gaps = 236/1645 (14%)
Query: 805 MLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIR 864
ML D P + + A E + E++ AA+ + + ++ D R
Sbjct: 97 MLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGS-SFDPQR 155
Query: 865 ESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRS 924
+ EA+ + E +P+ + S+ P QK ++ + S P R+R
Sbjct: 156 RAREAK-----QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERK 210
Query: 925 VSHGSN-HTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEK-PKKEGFIRSSEGPKPE 982
S H + + ++ + + PK + D K R PK RS+
Sbjct: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270
Query: 983 KVYKSKSETRWG-------------PRPSSNRREEVNDRPVRRSGPI--KKPVLRDM--K 1025
S+S +R P P+S RR E D P G ++P + K
Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE-GDAPFSEPGTTSTQRPSSPETATK 329
Query: 1026 EEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPP---------PQPPA--PIQPQ 1074
+ ++K+ +K EK + PE++ PP P P PQP A P+ +
Sbjct: 330 QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
Query: 1075 SVPPPIQ--PEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVV 1132
V PP + P ++ P L Q S ++ P P V++ ++P
Sbjct: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP---------SPQPTKVSRHASSSP-- 438
Query: 1133 KEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYR-GRGRG 1191
E +P P P S + T R++ + R++ R GR R
Sbjct: 439 -ESPKP-----------APAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR- 485
Query: 1192 EYYSRGRSYRGSYGGRGRGGRGHTRD-YPQYRDNK--PRAEHIPSGPLRQREESETRSES 1248
S + RG R RGH+R PQ+R ++ R S R R S R
Sbjct: 486 ---SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW 542
Query: 1249 SDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPD 1308
S +R R R + H + S+ + P R R ++ P + S +
Sbjct: 543 SRSRNTQRRGRSRSARR---GRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTP 599
Query: 1309 NHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRP 1368
R +R P RRGR + R P R SR R P
Sbjct: 600 TRRRSRSR---------------------TPARRGRSRS-----RTPARRRSR---TRSP 630
Query: 1369 AYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPK--FERKFDPARE--RPRRQR 1424
R ++ + P RR + + P + R PAR R R +
Sbjct: 631 VRRRSRSRSPARRSGRSRSRTPARRGR-----SRSRTPARRGRSRSRTPARRSGRSRSRT 685
Query: 1425 PTRPPR-QDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDL 1483
P R R + + PR R R R + P + + E N +
Sbjct: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKN-----KSRTSQRR 740
Query: 1484 SNQNSSDQANEEWETASESSDFNERRERDEKK---NADLNAQTVVKVGENVLPPKREIAK 1540
S NSS + + ++ S + R + + + L+ + ++ PP+R
Sbjct: 741 SRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR---S 797
Query: 1541 RSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDL 1600
RS SS Q + + PP+ R+ S P +++S PS+ P +G
Sbjct: 798 RSGSS------QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ-SHSSSSPHPKVKSGTPP 850
Query: 1601 INGSSAHHQEGVPNGTGQK-----NSKDSTGKKREDPK---PGPKKPKEKVDALSQFDLN 1652
GS Q + T Q+ +S D K R + G P+ K + +
Sbjct: 851 RQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS 910
Query: 1653 NYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKK 1712
+S P+V I P+ + S R+ ++ V N +
Sbjct: 911 RSSS-----PQPKVKAIISPRQRSHSGS-----SSPSPSRVTSRTTPRRSRSVSPCSNVE 960
Query: 1713 NANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVP-PLASAPLPPSTSASVPASTSAPLP 1771
+ S + P K T +Q+ S + P P A PP S S + +P P
Sbjct: 961 SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS---GSKSPCP 1017
Query: 1772 ATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSS 1831
+ S P S A V +ST P VS S + S + TSS
Sbjct: 1018 QEKSKDSLVQSCPGSLSLCAGVKSSTP---PGESYFGVS-SLQLKGQSQTSPDHRSDTSS 1073
Query: 1832 SAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAP 1891
+ + +P L S S + + +S P+ + LAS S P A+P++ +
Sbjct: 1074 PEVRQSHSESPSLQSKSQTSPKGGRSRSSSPV--TELASRS-PIRQDRGEFSASPMLKSG 1130
Query: 1892 TIP---------ASAPTA-SVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQ 1941
P +S PT S L S A + ++ P P A A Q K
Sbjct: 1131 MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALP-PQEDATASPPRQKDKFSP 1189
Query: 1942 NPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWD-------N 1994
P+Q +SS ++R P + +G S +T + + L D
Sbjct: 1190 FPVQDRPESSLVFKDTLRTPPRERS------GAGSSPETKEQNSALPTSSQDEELMEVVE 1243
Query: 1995 KVAPPA--VLNDISKKLGPISPPQ-PPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGT 2051
K PA +L+ +S +L +S S +P S S A +E+ +
Sbjct: 1244 KSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQA---SLEAVEVPS 1300
Query: 2052 DTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPI----KAQKLPDLS-P 2106
+G P + E+ S + P E R P + ++ DL+ P
Sbjct: 1301 MASSWGGPHFSPEHKELSN--SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGP 1358
Query: 2107 VENK-EHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTD-------PVTTKET 2158
N+ E P KE+S ++ + ++ P+ EK ++ +S P T
Sbjct: 1359 FLNQLETDPSLDMKEQSTRS-SGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRE 1417
Query: 2159 KAVSEMSTEIGTMISVSSAE-------------YGTNAKESVTDYTTPSSSLPNTVATNN 2205
++ S S E+ + + + GT ++ S++ + +P T +
Sbjct: 1418 RSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGR 1477
Query: 2206 TKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVRE 2265
++ + + P P LP R + SS P + + R E+S V +
Sbjct: 1478 SECDSS-----PEPKALPQTPRPRSRSPSS-----PELNNKCLTPQRERSGSESS--VDQ 1525
Query: 2266 KGSPVTSTAPPIATGVSSSAS-GPSTANYNSFSSASMPQIPVASVTPTASLSGAGTY--- 2321
K T +G S PS + S S P + TP S +G+
Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV 1585
Query: 2322 -TTSSLSTKSTTTSDPPNICKVKPQ 2345
+ S LS + + + P + K KP+
Sbjct: 1586 DSKSRLSPRRSRSGSSPEV-KDKPR 1609
Score = 98.6 bits (244), Expect = 8e-20
Identities = 491/2637 (18%), Positives = 896/2637 (33%), Gaps = 429/2637 (16%)
Query: 412 LLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEER 471
LL + P ++ PG+ Q+A+ +E +R R IS + +
Sbjct: 98 LLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV--------DGS 149
Query: 472 RMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKER 531
+ QR+A A KQP+PE + +E + +Q ++K++
Sbjct: 150 SFDPQRRAREA--------------KQPAPEPPKPYSLVRESSSSRSPTPKQ---KKKKK 192
Query: 532 EKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEK 591
+KDR R+ E +E++K + +K R + + K+ + + K +K K+++++
Sbjct: 193 KKDRGRRSESSSP-RRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRK----- 246
Query: 592 EREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPES 651
R + P + + + S + + + D++RS + T +
Sbjct: 247 -----------RSRSTTPAPKSRRAHRSTSADSA---SSSDTSRSRSRSAAAKTHTTALA 292
Query: 652 GSQPRPAVLSGY------------FKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQT 699
G P PA SG Q+ P +Q + + +++ +
Sbjct: 293 GRSPSPA--SGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP 350
Query: 700 VPSQPSSSTVPPPP-----------------------HRPLYQPMQPHPQHLASMGFDPR 736
PS SST P PP P+ P + P S P
Sbjct: 351 SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPE 410
Query: 737 WLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLM---RRDQMEGSPNSSESFEHIARSA 793
L S + S +P PKP ++ SP S A+
Sbjct: 411 KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRD 470
Query: 794 RDHAISLSEPRMLWGSDPYPHAEPQQATTP-----KATEEPEDVRSEAALDQEQITAAYS 848
+ H+ + S S ++ TP + P+ RS +A ++ + S
Sbjct: 471 KSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSA---QRWGRSRS 527
Query: 849 VEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPH-HTDANNQSACFEAPDQKTLSAP 907
+ P+ S Q ++ SRS R H + A + P ++ S
Sbjct: 528 PQRRGRSRSPQRPGWSRSRNTQ-RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586
Query: 908 Q-EERISAVESQPSRKRSVS-----HGSNHTQKPDEQRSEPSAGI--------PKVTSRC 953
+ R + P+R+RS S G + ++ P +RS + + P S
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGR 646
Query: 954 IDSKEPIERPEEK---PKKEGFIRS---------SEGPKPEKVYKSKSETRWGPRPSSN- 1000
S+ P R + P + G RS S P + +S+S T R S
Sbjct: 647 SRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRS 706
Query: 1001 --RREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKV-------VVKPE 1051
RR + R +R G R K QR+ + E ++ + P
Sbjct: 707 LVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPR 766
Query: 1052 KTEKKDLP-PPPPPPQPPAPIQPQSVPP------PIQPEAEKF--PSTETATLAQKPSQD 1102
K L P P Q PP QP+A+ P ++ + P Q
Sbjct: 767 SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQK 826
Query: 1103 TEKP-LEPVSTVQVEPAVKT---VNQQTMAAPVVKE-----------EKQPEKVISKDLV 1147
++ P + S+ P VK+ Q ++ +P E E P+ +
Sbjct: 827 SKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTP 886
Query: 1148 IERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGR 1207
S P K ST PPR ++ R P + + + R RS+ GS
Sbjct: 887 SRHSCSGSSPPRVKSST-PPR----QSPSRSSSP----QPKVKAIISPRQRSHSGS--SS 935
Query: 1208 GRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKR--RRQRGSET 1265
R +R P+ + ++ S L + S + S S D +V P+ R+
Sbjct: 936 PSPSRVTSRTTPRRSRSVSPCSNVESRLLPR--YSHSGSSSPDTKVKPETPPRQSHSGSI 993
Query: 1266 DTDSEIHESASDKDSLSKGKLPKREERPEN----------------KKPVKPHSSFKPDN 1309
++ SLS K P +E+ ++ K P S+ +
Sbjct: 994 SPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVS 1053
Query: 1310 HVRIDNRLLEKPYVRDDDKAKPGFLPKGE-PTRRGRGGTFRRGGRDPGGRPSRPSTLRRP 1368
+++ + P R D + E P+ + + T +GGR P R P
Sbjct: 1054 SLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
Query: 1369 AYRDN---QWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARER----PR 1421
+D +P PE + + ++ + + ++E+ P+
Sbjct: 1114 IRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQ 1173
Query: 1422 RQRPTRPPRQ-DKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKT 1480
PPRQ DK F E++ + + P P G +
Sbjct: 1174 EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTP-----------PRERSG---AGSS 1219
Query: 1481 PDLSNQNS----SDQANEEWETASESSD----FNERRERDEKKNADLNAQTVVKVGENVL 1532
P+ QNS S Q E E +S + + K+ + N ++ +V E
Sbjct: 1220 PETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPA 1279
Query: 1533 PPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQP 1592
+S +S V+ + + G P +FS E + P ++ P + +
Sbjct: 1280 VSLTLDQSQSQASLEAVEVPSMASSWGGP----HFSPEHKELSNSPLRENSFGSPLEFRN 1335
Query: 1593 AGTTGVDLINGSSAHHQEGVPNG--TGQKNSKDSTGKKREDPK-PGPKKPKEKVDALSQF 1649
+G G ++ G S+ +E + NG Q + S K + + G + DA+ +
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDL-NGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA 1394
Query: 1650 DLNNYASV--VIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQ 1707
+++ S+ ++D P T + S+ + + + + +R
Sbjct: 1395 GMSSNQSISSPVLDAVPR-TPSRERSSSASSPEMKDGLPRTPSRR--------------- 1438
Query: 1708 VWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTS 1767
++ + G S P R + S S P + P PS S S+
Sbjct: 1439 ---SRSGSSPGLRDGSGTPSRHS-----------LSGSSPGMKDIPRTPSRGRSECDSSP 1484
Query: 1768 APLPATLTPVPASTSAPVP-------------ASTLAPVLASTSAPVPASPLAPVSASAS 1814
P TP P S S P + + + V T A P + +S
Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQE 1544
Query: 1815 VSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAP 1874
+ AS + + SS + A TP+ + +S + + + + S S+
Sbjct: 1545 LDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604
Query: 1875 TPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAP--NPAPPAPAQT 1932
P A AP + + ++ P APA + P + + S+ P+P + T
Sbjct: 1605 KDKPRA---------APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSST 1655
Query: 1933 QAQ-THKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAEL 1991
++ H P + S+SS +P R P + + + + K+ + +S ++
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715
Query: 1992 WDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGT 2051
++ P ++ +S P+P S ++ S S + ++ G+ +
Sbjct: 1716 TRSRTPPR------HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK--P 1767
Query: 2052 DTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQ-------KQPRAGPIKAQKLP-- 2102
+Q S + + + + QR ++ R G + P
Sbjct: 1768 RGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPAR 1827
Query: 2103 -DLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEP----EGQEKPSPAT---VRSTDPVT 2154
+ S ++ + G+ R+ + + + P + + SPAT RS P+
Sbjct: 1828 QESSRTSSRRRR----GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLI 1883
Query: 2155 TK-----ETKAVSEMSTEIGTMIS-----VSSAEYGTNAKESVTDYTTPSSSLPNTVATN 2204
++ T VS + T ++ ++ S T T S T T
Sbjct: 1884 SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTR 1943
Query: 2205 NTKMEDT--LVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPN 2262
T + T P+ +R + ++S +T + S T + R SP
Sbjct: 1944 RRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR--RRSRSRTSPVTRRRSRSRTSPV 2001
Query: 2263 VREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYT 2322
R + TS P+ S S + P+ + + +P+ S +P A + + T
Sbjct: 2002 TRRRSRSRTS---PVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Query: 2323 TSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQS 2382
+ K + T PP I + S+ S+S S+ + P+
Sbjct: 2059 PRTARGKRSLTRSPPAI-------RRRSASGSSSDRSRSATPPA------------TRNH 2099
Query: 2383 AAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQ 2442
+ ++ P +++S + ++P L + + PG+ +P + P+ + G
Sbjct: 2100 SGSRTPPVALNSSRMSCFSRPSMSPTPLDRCR--SPGMLEPLGSSRTPMSVLQQAGG--- 2154
Query: 2443 AQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELA 2502
+ G GP + Q + + +Q + L+ TAI + T +
Sbjct: 2155 -SMMDGPGPRIPDHQR-------------TSVPENHAQSRIALALTAI-SLGTARPPPSM 2199
Query: 2503 KAQSGLAFQQTSNTQPIPIL---YEHQLGQASGLGGSQLIDTHLLQARA-NLTQASNLYS 2558
A +GLA + + P+P++ AS + + +L AR + A NL
Sbjct: 2200 SA-AGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLAD 2258
Query: 2559 GQVQQPGQTNFYN-----TAQSPSAL-----QQVTVP--------LPASQLSLPNFGSTG 2600
+ P N TA +PSA+ + T P PA+ +L GS G
Sbjct: 2259 SRT--PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGS-G 2315
Query: 2601 QPLIALPQTLQPPLQHTTPQAQAQSL---SRPAQVSQPFRGLIPAGTQHSMIATTGKMSE 2657
P P P TPQA A + R A + P AG++ + ++
Sbjct: 2316 TP----PTAANYPSSSRTPQAPASANLVGPRSAHATAPVN---IAGSRTAAALAPASLTS 2368
Query: 2658 MELKAFGSGIDIKPGTPPIA----------------GRSTTPTSSPFRATSTSPNSQSSK 2701
+ SG ++ P++ RS TP S+P ++ TS + S
Sbjct: 2369 ARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS 2428
Query: 2702 MNSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKAQ 2761
Q PA + P P+ F+ Q+ R + Q+T S+ + G
Sbjct: 2429 SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS--RCLIAQTT-----PVAGSQSLSSGAVA 2481
Query: 2762 KVDSDSSKPPETLTDP-PGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTEETKS 2817
S + L+ P PGV V E PPA + A +P ++P + + S
Sbjct: 2482 TTTSSAGDHNGMLSVPAPGVPHSDVGE--PPASTGAQQPSALAALQPAKERRSSSSS 2536
Score = 82.0 bits (201), Expect = 7e-15
Identities = 400/2068 (19%), Positives = 703/2068 (33%), Gaps = 319/2068 (15%)
Query: 902 KTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQ----RSEPSAGIPKVTSRC---- 953
++LS+P+ S +S+ S +RS+S GS+ K Q RS + PK SR
Sbjct: 760 RSLSSPR----SKAKSRLSLRRSLS-GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814
Query: 954 --IDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVR 1011
S P ++ + P ++ SS PK KS + R G S E+ + P R
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPK----VKSGTPPRQGSITSPQANEQ-SVTPQR 869
Query: 1012 RSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTE------------------KVVVKPEKT 1053
RS P ++K R G +V K ++ P +
Sbjct: 870 RSCFESSPD-PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928
Query: 1054 EKKDLPPPPPP--PQPPAPIQPQSVPPPIQPEAEKFPS-TETATLAQKPSQDTEKPLEPV 1110
P P P + +SV P E+ P + + + + E P
Sbjct: 929 SHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQS 988
Query: 1111 STVQVEPAVKTVNQQTMAAPVVKEEKQP---EKVISKDLVIER-PRPDSRPAVKKESTLP 1166
+ + P K V QT P + K P EK SKD +++ P S A K ST P
Sbjct: 989 HSGSISPYPK-VKAQTPPGPSLSGSKSPCPQEK--SKDSLVQSCPGSLSLCAGVKSSTPP 1045
Query: 1167 PRTYWKEAR-----ERDWFPDQGYRGRGRG--EYYSRGRSYRGSYGGRGRGGRGHTRDYP 1219
+Y+ + + PD + +S S + +GGR
Sbjct: 1046 GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRS------ 1099
Query: 1220 QYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKD 1279
R + P E P+RQ R E S ++ S +DS + +
Sbjct: 1100 --RSSSPVTELASRSPIRQ-----DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNS 1152
Query: 1280 SLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEP 1339
L + +L E + + P + ++ P R DK P +
Sbjct: 1153 LLGQSRLETAESKEKMALPPQEDATASPP---------------RQKDKFSPFPVQDRPE 1197
Query: 1340 TRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIP 1399
+ T R R+ G S P T + N P S+ E+ +
Sbjct: 1198 SSLVFKDTLRTPPRERSGAGSSPETKEQ-----NSALPTSSQ------------DEELME 1240
Query: 1400 IAADKRPPK---FERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVP 1456
+ P +E + P +++P L + ++ + S E V VP
Sbjct: 1241 VVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQA-SLEAVEVP 1299
Query: 1457 TNGTV----------NNVAQEPV--NTLGDI-----SGNKTPDLSNQNSSDQANE----- 1494
+ + ++ P+ N+ G SG +++ SS+ +
Sbjct: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
Query: 1495 --EWETASESSDFNERRERDE-KKNADLNAQTVVKVG----ENVLPPKREIAKRSFSSQR 1547
+ ET S D E+ R +++L+ V K G +++ P + R+ S +R
Sbjct: 1360 LNQLET-DPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRER 1418
Query: 1548 PVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAH 1607
+ +G P++ P RSG S G R +GT ++GSS
Sbjct: 1419 SSSASSPEMKDGLPRT------PSRRSRSG--SSPGLR-----DGSGTPSRHSLSGSSPG 1465
Query: 1608 HQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVT 1667
++ + ++ DS+ +PK P+ P+ + + S +LNN
Sbjct: 1466 MKDIPRTPSRGRSECDSS----PEPKALPQTPRPRSRSPSSPELNNKCLT---------- 1511
Query: 1668 VIEDPQSNLNDDGFTEVVSKKQQKRLQDEER-RKKEEQVIQVWNKKNANEKGRSQTSKLP 1726
PQ + G V +K R +R R Q + V K +A+ + RS++ P
Sbjct: 1512 ----PQRERS--GSESSVDQKTVARTPLGQRSRSGSSQELDV--KPSASPQERSESDSSP 1563
Query: 1727 PRFAKKQATGIQQAQSSASVPPLASAPLPP--STSASVPASTSAPLPATLTPVPASTSAP 1784
AK + Q+++S +S + + L P S S S P P A P + S
Sbjct: 1564 DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA-----PRAQSG- 1617
Query: 1785 VPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPIL 1844
S S+P P +P P + + + SS+ P+P
Sbjct: 1618 -----------SDSSPEPKAP-------------APRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 1845 ASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPL 1904
++ S+P +A +S T + TP SS ++P +T S + S
Sbjct: 1654 STESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA-RLSRRSRSASS 1712
Query: 1905 APASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNP-LQTTSQSSKQPPPS------ 1957
+P + S P + + PA ++ + +P +TTS+ + P P
Sbjct: 1713 SPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR 1772
Query: 1958 ----IRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS 2013
R +T D S +S + + + + + S
Sbjct: 1773 SRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR--------S 1824
Query: 2014 PPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLS 2073
P + S ++ P + ++ + + +PA++ P++S
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
Query: 2074 EKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPG--PIGKERSLKNRKVKDA 2131
+ + P +R+ + R + + SPV + + P+ + RS
Sbjct: 1885 RRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPT--- 1941
Query: 2132 QQVEPEGQEKPSPATVRS----TDPVTTKETKAVSEMSTEIGTMISVS--SAEYGTNAKE 2185
+ + P T R T PVT + +++ + T + S + +
Sbjct: 1942 --TRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
Query: 2186 SVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFS 2245
VT + S + P T + ++ + T LP++ + +S S ++ + S
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPA-IRRRSRSRTPLLPRKRS--RSRSPLAIRRRSRS 2056
Query: 2246 LTFKMESARKAWENSPNVREKGSPVTSTA-------PPIATGVSSSASGPSTAN---YNS 2295
T + +++ SP + S S++ PP S S + P N +
Sbjct: 2057 RTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSC 2116
Query: 2296 FSSASMPQIPVASVTPTASLSGAGTYTT--SSLSTKSTTTSDPPNICKVKPQQLQTSSLP 2353
FS SM P+ L G+ T S L + D P + Q +S+P
Sbjct: 2117 FSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPG---PRIPDHQRTSVP 2173
Query: 2354 SASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQ--------IPAFYMDTSHLFNTQHARL 2405
S+++ + I+ P +S + A +P + T+ N
Sbjct: 2174 ENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIP 2233
Query: 2406 APPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQ 2465
A + A + PT+V A + A P+ + + +
Sbjct: 2234 AASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAP 2293
Query: 2466 PYRSQPAFMQSSLSQPSVVLSGT--AIHNFPTVQHQELAKAQSGLAFQQTSN-TQPIPIL 2522
A ++L+ S+ SGT N+P+ A A + L ++++ T P+ I
Sbjct: 2294 AVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIA 2353
Query: 2523 YEHQLGQASGLGGSQLIDTHLLQAR--ANLTQ------ASNLYSGQVQQP----GQTNFY 2570
A+ L + L + A ANLT A SG+ P ++
Sbjct: 2354 GSRT---AAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP 2410
Query: 2571 NTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPP---------LQHTTPQA 2621
+A S S + P P+S++ S P P++ P + TTP A
Sbjct: 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA 2470
Query: 2622 QAQSLSRPAQVSQP-----FRGL--IPA-GTQHSMI----ATTGKMSEMELKAFGSGIDI 2669
+QSLS A + G+ +PA G HS + A+TG L A +
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530
Query: 2670 KPGTPPIAGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQPFPTQFA 2729
+ + + S++ +SS ++S+S S SS Q + A V P P +
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 2730 ---------PQAKQR---------AEVLQSTQRFFSEQQQSKQIGGGKAQKVDSDSSKPP 2771
P ++R + S+ S S + S SS P
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 2772 ETLTDPPGVCQEKVEEKPPPAPSIATKP 2799
P + + +KPPP + P
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSP 2678
Score = 73.2 bits (178), Expect = 3e-12
Identities = 355/1888 (18%), Positives = 646/1888 (34%), Gaps = 287/1888 (15%)
Query: 483 EKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEK- 541
E+L+RL+ L K+P+P+ + + ER+R EL + +E +E+ + ++ QEK
Sbjct: 40 EELRRLE---AALVKRPNPDIL-----DHERKRRVELRCLELEEMMEEQGYEEQQIQEKV 91
Query: 542 --------EKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQK----MKEQEKECEL 589
EK++ +++ ++ E + E ++K + L+
Sbjct: 92 ATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSF 151
Query: 590 EKEREKLEEK-IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETE 648
+ +R E K P P +V + S S +++ ++D R + ++P
Sbjct: 152 DPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSP--RRER 209
Query: 649 PESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ--QQQQGVLPQTVPSQPSS 706
+S + + S K+ +S P+ +R+ + K+++ + + S S+
Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
Query: 707 STVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAM-DIPPIHPGMI 765
S+ R + H LA P SGR D P PG
Sbjct: 270 SSSDTSRSRSRSAAAKTHTTALAG-------------RSPSPASGRRGEGDAPFSEPGTT 316
Query: 766 P---PKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATT 822
P + SP + + +SA S S R G +P P P A
Sbjct: 317 STQRPSSPETATKQPSSPYEDKDKDKKEKSAT--RPSPSPERSSTGPEP-PAPTPLLAER 373
Query: 823 PKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDV 882
+ +P + L QE + + EA P D S ++ + S
Sbjct: 374 HGGSPQP---LATTPLSQEPV-------NPPSEASPTRDRSPPKSPEKLPQSSSSESSPP 423
Query: 883 RPHHTD-ANNQSACFEAPDQKTLSAPQEER-ISAVESQPSR-----KRSVSHGSNHTQKP 935
P T + + S+ E+P K AP R IS+ + +R KR SH +++
Sbjct: 424 SPQPTKVSRHASSSPESP--KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM 481
Query: 936 DEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGP 995
RS +A + SR P K G RS + + +S+S RWG
Sbjct: 482 GRSRSPATAKRGRSRSR-------------TPTKRGHSRS----RSPQWRRSRSAQRWGR 524
Query: 996 RPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEK 1055
S RR RS ++P + + + + + + + + +
Sbjct: 525 SRSPQRR--------GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSR 576
Query: 1056 KDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQV 1115
+ PA + +S P + + P+ + ++ P++ + PV
Sbjct: 577 TPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSR 636
Query: 1116 EPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEAR 1175
+ + ++ + + + + ++ R R SR ++ RT + R
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPAR-----RGRSRSRTPARRSGRSRSRTPARRGR 691
Query: 1176 ERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGP 1235
R P +G R R R RGRS+ + RGR G R NK R
Sbjct: 692 SRSRTPRRG-RSRSR-SLVRRGRSHSRTPQRRGRSGSS------SERKNKSRT------- 736
Query: 1236 LRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLS-KGKLPKREERPE 1294
+ +RS SS P+ ++ R S + S + K LS + L P+
Sbjct: 737 ----SQRRSRSNSS-----PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787
Query: 1295 NKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRD 1354
K P S + + +R P R + P K + R + +
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSR---TPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKV 844
Query: 1355 PGGRPSRPSTLRRPAYRDNQWNPRQ----SEVPKPE-DGEPPRRHEQFIPIAADKRPPKF 1409
G P R ++ P + P++ P PE P RH + PP+
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS-----CSGSSPPRV 899
Query: 1410 ERKFDPARERPRRQRPTRP-------PRQ-----DKPPRFRRLREREAASKSNEVVAVPT 1457
+ P R+ P R +P PRQ P R+ R +S V
Sbjct: 900 -KSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV----- 953
Query: 1458 NGTVNNVAQEPVNTLGDISGNKTPDLS-----------NQNSSDQANEEWETASESSDFN 1506
+NV + SG+ +PD + + S + +T S
Sbjct: 954 -SPCSNVESRLLPRYSH-SGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSG 1011
Query: 1507 ERRERDEKKNADLNAQTV-----VKVGENVLPPKRE----IAKRSFSSQRPVDRQNRRGN 1557
+ ++K+ D Q+ + G P E ++ Q +R
Sbjct: 1012 SKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT 1071
Query: 1558 NGP-------------------PKSGRN-FSGPRNERRSGPPSKSGKRGPFDDQPAGTTG 1597
+ P PK GR+ S P E S P + RG F P +G
Sbjct: 1072 SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQ-DRGEFSASPMLKSG 1130
Query: 1598 VD-----LINGSSAHHQEGVPNGTGQKNSKDSTGKKR------EDPKPGPKKPKEKVDAL 1646
+ + SS++ + GQ + + K++ ED P + K+K
Sbjct: 1131 MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF--- 1187
Query: 1647 SQFDLNNYASVVIIDDHPEVTVI-----EDPQSNLNDDGFTEVVSKKQQKRL----QDEE 1697
S + D PE +++ P + G + +K+Q L QDEE
Sbjct: 1188 ---------SPFPVQDRPESSLVFKDTLRTPPRERSGAG-SSPETKEQNSALPTSSQDEE 1237
Query: 1698 R----RKKEEQVIQVWNKKNANEKGRSQTS-KLPPRFAKKQATG--IQQAQSSAS----- 1745
K EE Q+ + ++ K S ++ + P ++ A + Q+QS AS
Sbjct: 1238 LMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVE 1297
Query: 1746 VPPLASAPLPPSTSASVPASTSAPLPATL--TPVPASTSAPVPASTLAPVLASTSAPVPA 1803
VP +AS+ P S +++PL +P+ S P+ + +
Sbjct: 1298 VPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNG 1357
Query: 1804 SPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPI 1863
L + S+ ++ S+ +S +P + A +S+ S++ ++P
Sbjct: 1358 PFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEK-----AGMSSNQSISSPVLDAVPR 1412
Query: 1864 LASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPN 1923
S S+SA +P P P + + S P + P+ S+P
Sbjct: 1413 TPSRERSSSASSPEMKDGLPRTP-------SRRSRSGSSPGLRDGSGTPSRHSLSGSSPG 1465
Query: 1924 ----PAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTP----NGTDYVASG 1975
P P+ +++ + + QT S+ P TP +G++
Sbjct: 1466 MKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ 1525
Query: 1976 KSI-QTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAP 2034
K++ +TP + + + V P A + S+ S P S + PL
Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERSE-----SDSSPDSKAKTRTPLRQ----R 1576
Query: 2035 SSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAG 2094
S G+ +S + + G+ ++ P ++ +D PEPK PRA
Sbjct: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP-RAQSGSDSSPEPK---APAPRAL 1632
Query: 2095 PIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVT 2154
P +++ S +K P P G + + + + G +S P
Sbjct: 1633 PRRSR-----SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR 1687
Query: 2155 TKETKAVSEMS--TEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTL 2212
+ +++ E++ + +S+ T ++ +PS S P + +
Sbjct: 1688 RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
Query: 2213 VNNVPLPNT-----LPLPKRETIQQSSS 2235
++ T P PK +Q+S S
Sbjct: 1748 ASSPRTKTTSRRGRSPSPKPRGLQRSRS 1775
Score = 72.8 bits (177), Expect = 5e-12
Identities = 105/467 (22%), Positives = 181/467 (38%), Gaps = 53/467 (11%)
Query: 1727 PRFAKKQATGIQQAQSSASVPPLA-SAPLPPSTSASVPAST---SAPLPATLT-PVPAST 1781
PR A + A++ A++ L+ + P T+A+ P+S+ AP A L P A
Sbjct: 2287 PRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA 2346
Query: 1782 SAPV------PASTLAPVLASTSAPVPA-------SPLAPVSASASVSA--SVPASTSAA 1826
+APV A+ LAP +++ PA SP P+SA VS S P A
Sbjct: 2347 TAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRAR 2406
Query: 1827 AITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAP 1886
+ T SAP+ + + S P+ + + A L A +P P+A S +
Sbjct: 2407 SRTPPSAPSQSR-----MTSERAPSPSSRMGQAPSQSLLPP-AQDQPRSPVPSAFSDQSR 2460
Query: 1887 VITAPTIPA--SAPTASVPLAPASASA-------PAPAPTPVSAPNPAPPAPAQTQAQTH 1937
+ A T P S +S +A ++SA PAP + PPA Q +
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
Query: 1938 KPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVA 1997
P + SS S S+ + + + + S + S + E+ +V
Sbjct: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP 2580
Query: 1998 PPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFG 2057
P + + G PP+P + +S S+ SS + + S + +
Sbjct: 2581 SPTPAPKEAVREG--RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638
Query: 2058 APASNGNENEVVPV------LSEKSADKIPEPKEQRQKQPR--AGPIKAQKLPDLSPVEN 2109
+ +S+ + + P L + ++ K P P E+R + PR ++ + SPVE
Sbjct: 2639 SSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVER 2698
Query: 2110 KEHKPGPIGKER--------SLKNRKVKDAQQVEPEGQEKPSPATVR 2148
+ P P +++ S + ++ +E PSP +R
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR 2745
Score = 65.1 bits (157), Expect = 9e-10
Identities = 276/1395 (19%), Positives = 477/1395 (34%), Gaps = 278/1395 (19%)
Query: 1027 EREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPP---PPPPPQPPAPIQPQSVPPPIQPE 1083
E E+ E++G + +++ EKV +KD+ P P Q PA
Sbjct: 72 ELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPA-------------- 117
Query: 1084 AEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVIS 1143
TET LA+ + E+ + + Q A +E KQP
Sbjct: 118 -----VTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRA----REAKQPAP--- 165
Query: 1144 KDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGS 1203
E P+P S S P K+ +++D RGR S
Sbjct: 166 -----EPPKPYSLVRESSSSRSPTPKQKKKKKKKD-----------------RGRRSESS 203
Query: 1204 YGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGS 1263
R R + + ++K R P+ +++ + + R S PK RR S
Sbjct: 204 SPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS 263
Query: 1264 ETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYV 1323
T DS ++S S S+ + K H++
Sbjct: 264 -TSADS----ASSSDTSRSRSR----------SAAAKTHTT------------------- 289
Query: 1324 RDDDKAKPGFLPKGEPTRRGRG-GTFRRGGRDPGGRPSRPST-LRRPA--YRDNQWNPRQ 1379
A G P RRG G F G RPS P T ++P+ Y D + ++
Sbjct: 290 -----ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
Query: 1380 SEV----PKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPP 1435
P PE P+ A++ + P P Q P PP + P
Sbjct: 345 KSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ----PLATTPLSQEPVNPPSEASPT 400
Query: 1436 RFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEE 1495
R R + KS E +P + + + P T + +P+ + ++ E
Sbjct: 401 RDR------SPPKSPE--KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452
Query: 1496 WETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPP--------KREIAKRSFS-SQ 1546
++ S + + R + +K ++ ++ ++G + P R KR S S+
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSR---RMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509
Query: 1547 RPVDRQNRRG-----NNGPPKSGRN-------FSGPRNERRSGPPSKSGKRGPFDDQPAG 1594
P R++R + P + GR+ +S RN +R G S+S +RG +
Sbjct: 510 SPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG-RSRSARRGRSHSRSPA 568
Query: 1595 TTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNY 1654
T G + P G+ S+ ++ P ++ + + A +
Sbjct: 569 TRG---------RSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619
Query: 1655 ASVVIIDDHPEVTVIEDPQSNLNDDG--FTEVVSKKQQKRLQDEERRKKEEQVIQVWNKK 1712
+ V +S G + +++ + R + RR + ++
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSR------SRT 673
Query: 1713 NANEKGRSQT----------SKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPS----- 1757
A GRS++ S+ P R + + +++ +S + P S
Sbjct: 674 PARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK 733
Query: 1758 --TSASVPASTSAP-LPATLTPVPASTSAPVPASTLAPVLA-----STSAPVPASPLAPV 1809
TS S S+P + + S S P S L+ S S+P P
Sbjct: 734 SRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTP 793
Query: 1810 SASASVSASVPASTSAA----AITSSSAPASAPAPTPILASVSTPASVTILASASIP--- 1862
+ +S P + S + +SSS P + TP S S+ + + S + P
Sbjct: 794 PRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853
Query: 1863 ILASALASTSAPTPAPAA--SSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVS 1920
+ S A+ + TP + S P + + T + + S P S++ P +P+ S
Sbjct: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913
Query: 1921 APNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQT 1980
+P P K + +P Q + S P PS R+ S TP + V+ ++++
Sbjct: 914 SPQPKV-----------KAIISPRQRSHSGSSSPSPS-RVTSRTTPRRSRSVSPCSNVES 961
Query: 1981 ----PQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSS 2036
SH ++ D KV P G ISP P V A P PS
Sbjct: 962 RLLPRYSHSGSSSP--DTKVKPETPPR--QSHSGSISP--YPKVKAQTPP------GPSL 1009
Query: 2037 EGAKNGQESGLEIGTDTIQFGAPAS----NGNENEVVPVLSEKSADKIPEPKEQRQKQPR 2092
G+K+ E D++ P S G ++ P S + + K Q Q P
Sbjct: 1010 SGSKS--PCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSL-QLKGQSQTSP- 1065
Query: 2093 AGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDP 2152
+ SP + H P ++ + Q P RS+ P
Sbjct: 1066 -----DHRSDTSSPEVRQSHSESP----------------SLQSKSQTSPKGGRSRSSSP 1104
Query: 2153 VTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTL 2212
VT E + S + + G + + G + ++S + + SSS P +N+ + +
Sbjct: 1105 VT--ELASRSPIRQDRGEFSASPMLKSGMSPEQS--RFQSDSSSYP--TVDSNSLLGQSR 1158
Query: 2213 VNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESA-------------RKAWEN 2259
+ + LP +E S + F + + ES+ R +
Sbjct: 1159 LETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGS 1218
Query: 2260 SPNVREKGSPVTST----------------APPIATGVSSSASGPSTANYNSFSSASMPQ 2303
SP +E+ S + ++ A I + +SS ST+N+ SS + +
Sbjct: 1219 SPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFE--SSPEVEE 1276
Query: 2304 IPVASVTPTASLSGA 2318
P S+T S S A
Sbjct: 1277 RPAVSLTLDQSQSQA 1291
Score = 62.4 bits (150), Expect = 6e-09
Identities = 65/277 (23%), Positives = 121/277 (43%), Gaps = 5/277 (1%)
Query: 1686 SKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSAS 1745
S Q R+ E ++ Q ++ S +P F+ + I Q A
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471
Query: 1746 VPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASP 1805
L+S + +TS++ + +PA VP S PAST A ++ +A PA
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAP--GVPHSDVGEPPASTGAQQPSALAALQPAKE 2529
Query: 1806 LAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILA 1865
S+S+S S+S +S+S+++ +SSS +S+ + L A + + P A
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589
Query: 1866 SALASTSAPTPAPA---ASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAP 1922
PTPA +SS ++ ++ + +S+ ++S + +S+S+ + + + S+P
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
Query: 1923 NPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIR 1959
+PA P P P + S+S ++P S+R
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLR 2686
Score = 49.3 bits (116), Expect = 5e-05
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 19/207 (9%)
Query: 1718 GRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPV 1777
G Q S L A + A + + SS+S +S+ S+S+S S+S+ + PV
Sbjct: 2514 GAQQPSALA---ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570
Query: 1778 -PASTSAPVPASTLAPVLASTSA----PVPASPLAPVSASASVSASVPASTSAAAITSSS 1832
P VP+ T AP A P PA S+S+S S+S +S+S+++ +SSS
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 1833 APASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAAS-SPAAPVITAP 1891
+ +S+ + + +S S+ S ++P AS P P S SP P
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALP----KPASPKKPPPGERRSRSPRKP----- 2681
Query: 1892 TIPASAPTASVPLAPASASAPAPAPTP 1918
I + + S+ +P P+P P+P
Sbjct: 2682 -IDSLRDSRSLSYSPVERRRPSPQPSP 2707
Score = 45.1 bits (105), Expect = 0.001
Identities = 105/619 (16%), Positives = 201/619 (32%), Gaps = 52/619 (8%)
Query: 58 ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVP-----PAQPKPGVAAPP 112
A P + G+ +++ P AS QE+ E + +P+ P + + + P
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPS-----ASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583
Query: 113 EVAPAPKSWASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKEKETNDDNYGPGPSLRP 172
EV KS S ++ G +V + + P Q+ D + K P P P
Sbjct: 1584 EVDS--KSRLSPRRSRSGSSPEVKDK-PRAAPRAQSGSDSSPEPK-------APAPRALP 1633
Query: 173 PNVACWRDGGKAAG---SPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAK 229
R G + G SP S E P + + T+ + K + PP+ +
Sbjct: 1634 RRS---RSGSSSKGRGPSPEGSSSTESSP-EHPPKSRTARRGSRSSPEPKTKSRTPPRRR 1689
Query: 230 LNGQQAALASQYRAMMPPYMFQQYP--RMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSW 287
+ L + R P R PP H R PS+S + R
Sbjct: 1690 SSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH---RRSPSVSSPEPAEKSRSS---- 1742
Query: 288 ASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKE 347
R S+ K + + G ++ + D GS+
Sbjct: 1743 ----RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTS 1798
Query: 348 NNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLP 407
+ S++ + + S + + + S + + P +++R S P
Sbjct: 1799 RRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858
Query: 408 PPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRRE 467
P K + P + R ++ + + RRR +S S R+R R
Sbjct: 1859 APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV--SRRRSRSRTSVTRRRSRSRAS 1916
Query: 468 EEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQER 527
RR R + R ++ S R + R R + + + + R
Sbjct: 1917 PVSRRRSRSRTPPVTRRRSRSRTP---TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSR 1973
Query: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC 587
+ R R + + + + + + R + + + R++ + + ++ + +
Sbjct: 1974 TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSR 2033
Query: 588 E--LEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRS---EKEATP 642
L ++R + + R + + S + + R S S + ATP
Sbjct: 2034 TPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATP 2093
Query: 643 VVHETEPESGSQPRPAVLS 661
T SGS+ P L+
Sbjct: 2094 PA--TRNHSGSRTPPVALN 2110
Score = 39.7 bits (91), Expect = 0.043
Identities = 79/412 (19%), Positives = 137/412 (33%), Gaps = 63/412 (15%)
Query: 660 LSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQ 719
LS Y + ++ PP R + + Q + + PS SS + P + L
Sbjct: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS---ERAPSP--SSRMGQAPSQSLLP 2441
Query: 720 PMQPHPQHLASMGFDPRWLMMQSYMDP-----RMMSGRPAMDIPPI--HPGMIP-PKPLM 771
P Q P+ F + + + P + SG A H GM+ P P
Sbjct: 2442 PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP-- 2499
Query: 772 RRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPED 831
G P+S + A+ +P L P +++ ++
Sbjct: 2500 ------GVPHSDVGEPPASTGAQ-------QPSALAALQPAKERRSSSSSSSSSSSSSSS 2546
Query: 832 VRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANN 891
S ++ +++ S E + L P+ R S K R P
Sbjct: 2547 SSSSSSSSSSGSSSSDS-EGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
Query: 892 QSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTS 951
+S+ + + S+ S+ S S S S S+ + P + P A +PK S
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA-LPKPAS 2664
Query: 952 RCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVR 1011
P++ P E RS P K S ++R ++ PV
Sbjct: 2665 -----------PKKPPPGERRSRS-----PRKPIDSLRDSR-----------SLSYSPVE 2697
Query: 1012 RSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPP 1063
R P +P RD + +R + G++ + + P +++ P P P
Sbjct: 2698 RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS------PSHKRRRETPSPRP 2743
Score = 35.8 bits (81), Expect = 0.61
Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 10/140 (7%)
Query: 342 SNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERG 401
S+S ++S S +S ++ + + S++ SSS PA+P +P P
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE 2672
Query: 402 TSSHLPPPP-----KLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEIS 456
S P P + + P +R+ RP P PS + RR Q+ + S
Sbjct: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERR----RPSPQPSPRDQQSSSSERGSRRGQRGD-S 2727
Query: 457 AAVERARKRREEEERRMEEQ 476
+ R+R R M +
Sbjct: 2728 RSPSHKRRRETPSPRPMRHR 2747
Score = 35.0 bits (79), Expect = 1.0
Identities = 46/179 (25%), Positives = 65/179 (36%), Gaps = 24/179 (13%)
Query: 1252 EVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHV 1311
E P +R++R S + + S S+S S S + SS +
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSPSPA 2652
Query: 1312 RIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGG-RDPGGRPSRPSTLRRPAY 1370
+ + L KP A P P GE RR R RD P RRP+
Sbjct: 2653 KPGPQALPKP-------ASPKKPPPGE--RRSRSPRKPIDSLRDSRSLSYSPVERRRPS- 2702
Query: 1371 RDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPP 1429
Q +PR + E G RR ++ D R P +R+ + RP R R +R P
Sbjct: 2703 --PQPSPRDQQSSSSERGS--RRGQR-----GDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 32.7 bits (73), Expect = 5.2
Identities = 45/247 (18%), Positives = 91/247 (36%), Gaps = 27/247 (10%)
Query: 282 GPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQG 341
G PP+ ++ ++PS L+A + + + + + + + + + S D +G
Sbjct: 2507 GEPPA-STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 342 SN-----------------SPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPS 384
S+ +PKE E + + + ++ + S++ SSS + S
Sbjct: 2566 SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625
Query: 385 VAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRP-GPFPSKQQVADEDE 443
+ S + +SS P P P P P P P P +++ +
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSP-----AKPGPQALPKPASPKKPPPGERRSRSPRK 2680
Query: 444 IWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQ---PS 500
R +S + VER R + R + + + +R D + +++ PS
Sbjct: 2681 PIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740
Query: 501 PEEIRER 507
P +R R
Sbjct: 2741 PRPMRHR 2747
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 132 bits (331), Expect = 6e-30
Identities = 187/891 (20%), Positives = 306/891 (34%), Gaps = 87/891 (9%)
Query: 1479 KTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENV-LPPKRE 1537
++P N+ + + E E E S +E +E ++ ++ T+ K+ + RE
Sbjct: 94 RSPKPPNKKKTKKVIESEEITEEHS-VSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE 152
Query: 1538 IAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNE--RRSGPPSKSGKRGPFDDQPAGT 1595
+ K+ +R ++ PP SG N + + P + + + P T
Sbjct: 153 LQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 212
Query: 1596 TGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDP---KPGPKKPKEKVDALSQFDLN 1652
T + S T +K++T + +E K KEK + +
Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 272
Query: 1653 NYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDE--ERRKKEEQVIQVWN 1710
S + +V P++ G K+ E KE + +
Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 332
Query: 1711 KKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPL 1770
++ T+K P K+ A P P P + P +T P
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPA------------PTTTKEPAPTTPKEPAPTTTKEPA 380
Query: 1771 PATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITS 1830
P T P + P P + P + P P +P P + A +T A T+
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TTKEPAPTT 437
Query: 1831 SSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITA 1890
PA P + PA T A + + P P S+P A
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 497
Query: 1891 PTIPASAPTASVPLAPASASAPAPA----PTPVSAPNPAPPAPAQTQAQTHKPVQNPLQT 1946
PT SAPT +P + PAP P P + PAP P + T K P T
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK---EPAPT 554
Query: 1947 TSQSSKQPPPSIRLPSAQTPNGTDYVASGK-SIQTPQSHGTLTAELWDNKVAPPAVLNDI 2005
T++ K P + + P+ TP T K + TP+ T E K AP
Sbjct: 555 TTK--KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTT----- 603
Query: 2006 SKKLGPISPPQP-PSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGN 2064
++L P +P +P P+ P T +AP++ + + E T + AP +
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKE 662
Query: 2065 ENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKE------HKPGPIG 2118
P + + K P P ++ P+ +L+P KE KP P
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPK----------ELAPTTTKEPTSTTCDKPAP-- 710
Query: 2119 KERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAE 2178
+ K ++ P ++P+P T + T P T KE T + E
Sbjct: 711 --TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT--------TPKKPAPKE 760
Query: 2179 YGTNAKESVTDYTT--PSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSL 2236
+ T T+ P+ + P A K P P T P T + S+
Sbjct: 761 LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT 820
Query: 2237 TSVPPTTFSLT-------FKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPS 2289
T+ PTT + E KA ENSP +E G P T T ++++A +
Sbjct: 821 TTKEPTTIHKSPDESTPELSAEPTPKALENSP--KEPGVPTTKTPAATKPEMTTTAKDKT 878
Query: 2290 T---ANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPP 2337
T ++ + P++ + T T + + T++ T +TT P
Sbjct: 879 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 929
Score = 115 bits (289), Expect = 5e-25
Identities = 191/922 (20%), Positives = 309/922 (33%), Gaps = 93/922 (10%)
Query: 1401 AADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPR------FRRLREREAASKSNEVVA 1454
AA++ K + D + R +++ +PP D+ F+ + ++ N+V
Sbjct: 148 AANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST 207
Query: 1455 VPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERD-- 1512
P T +P+N + N D S + S E E++ N++ D
Sbjct: 208 SPKITTA-----KPINPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGK 260
Query: 1513 EKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRN 1572
EK + Q++ K L P ++ + PK+ GP
Sbjct: 261 EKTTSAKETQSIEKTSAKDLAPTSKVLAKP-----------------TPKAETTTKGPAL 303
Query: 1573 ERRSGPPSKSGKRGPFDDQPAGTTGVD----LINGSSAHHQEGVPNGTGQKNSKDSTGKK 1628
P + K +PA TT + I + +E P T +
Sbjct: 304 TTPKEPTPTTPK------EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 357
Query: 1629 REDPKPGPKKPKEKVDALSQFDL-NNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSK 1687
+P P PKE ++ S P T + P + +
Sbjct: 358 TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE--PAPTTP 415
Query: 1688 KQQKRLQDEERRKKEEQVIQVWNKK---NANEKGRSQTSKLPPRFAKKQATGIQQAQSSA 1744
K+ +E ++ K+ A +K T K P K+ + S
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 475
Query: 1745 SVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPAS 1804
+ P + P+T+ S P +T P P T P + P P +T P + P P +
Sbjct: 476 TTPKEPA----PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 531
Query: 1805 PLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPIL 1864
P P + A A T AP + P P + P + L + L
Sbjct: 532 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Query: 1865 ASALASTSAPTPAPAASSPAAPVITAPTIPAS-APTASVPLAPASASAPAPA----PTPV 1919
A APT P +P P PT P APT AP + PAP P P
Sbjct: 592 APTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 650
Query: 1920 SAPNPAPPAPAQTQAQTHK-----PVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVAS 1974
+ PAP P +T T K ++ P TT K+P P P+ T T
Sbjct: 651 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTT-TKEPTSTTCD 706
Query: 1975 GKSIQTPQSHGTLT----AELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSF 2030
+ TP+ T A + AP L +P P + T+
Sbjct: 707 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 766
Query: 2031 GSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQ-- 2088
S+ K + E T + AP + P + ++ P ++
Sbjct: 767 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 826
Query: 2089 ---KQPRAGPIKAQKLPDLSPVENKEHKPG-PIGK-ERSLKNRKVKDAQQVEPEGQEKPS 2143
K P + P +EN +PG P K + K A+ E + +
Sbjct: 827 TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 886
Query: 2144 PATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDY---TTPSSSLPNT 2200
P T + P TKET +E +TE + I+ ++ + + + T + T +++L
Sbjct: 887 PETTTAA-PKMTKETATTTEKTTE--SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 943
Query: 2201 VATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENS 2260
V T + T + N P P ++ S + T P K S +K +
Sbjct: 944 VTTTKKTITTTEIMNKPEETAKP---KDRATNSKATTPKPQKPTKAPKKPTSTKKP-KTM 999
Query: 2261 PNVRE-KGSP----VTSTAPPI 2277
P VR+ K +P +TST P +
Sbjct: 1000 PRVRKPKTTPTPRKMTSTMPEL 1021
Score = 60.8 bits (146), Expect = 2e-08
Identities = 82/380 (21%), Positives = 135/380 (35%), Gaps = 47/380 (12%)
Query: 801 SEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKA 860
S P P ++ ++TT ++ + P +++ ++ E+IT +SV NQ
Sbjct: 71 SPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ------- 123
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPS 920
ESS + S ++ ++ A N+ QK L ++ +
Sbjct: 124 ----ESSSSSSSSSSSSTIRKIKSSKNSAANREL------QKKLKVKDNKKNRTKKKPTP 173
Query: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPK----VTSRCIDSKEPIE-RPEEKPKKEGFIRS 975
+ V + D + + P + TS I + +PI RP P + +
Sbjct: 174 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 233
Query: 976 SEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKE 1035
S E ++K T + S++ +E+ + + I+K +D+
Sbjct: 234 SLTVNKETTVETKETTTTNKQTSTDGKEKTTS--AKETQSIEKTSAKDL----------- 280
Query: 1036 GEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPP--PIQPEAEKFPST--E 1091
KV K K E T K P P P P +P S P P + P+T E
Sbjct: 281 -APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE 339
Query: 1092 TATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERP 1151
A K + T P EP T EPA T + AP +E P S + P
Sbjct: 340 PAPTTTKSAPTT--PKEPAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKEP 394
Query: 1152 RPDS--RPAVKKESTLPPRT 1169
P + +PA P T
Sbjct: 395 APTTPKKPAPTTPKEPAPTT 414
Score = 55.8 bits (133), Expect = 6e-07
Identities = 153/842 (18%), Positives = 275/842 (32%), Gaps = 96/842 (11%)
Query: 403 SSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERA 462
SS PPP +Q +++ P P +K+ V + +EI ++ +++ S++ +
Sbjct: 74 SSKKAPPPSGASQTIKSTTKRS-PKPPNKKKTKK-VIESEEITEEHSVSENQESSSSSSS 131
Query: 463 RKRREEEERRMEEQRKAACAE---KLKRLDEKLGILEKQPSPEE--IREREREKEREREK 517
+ + AA E KLK D K +K+P+P+ + E + K
Sbjct: 132 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 191
Query: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ--EKEKELERQKEKEK 575
+ + + + K + KE KE +E ++
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 251
Query: 576 ELQKMKEQEKECELEKEREKLEEK----IEPREPNLEPMVEKQESEN-----SCNKEEEP 626
Q + +++ KE + +E+ + P L K E+ + KE P
Sbjct: 252 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 311
Query: 627 VFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ 686
++ ++ + KE TP ++ P + +P P K P ++ ++
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPTTTKEPAPTTPKE 370
Query: 687 WQQQQQQGVLPQTVPSQPSSSTVPPP--PHRPL-YQPMQPHPQHLASMGFDPRWLMMQSY 743
+ P T S P++ P P P +P P +P P P+ +
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-------TPKEPTPTTP 423
Query: 744 MDPRMMSGRPAMDIP---------------PIHPGMIPPKPLMRRDQMEGSPNSSE---- 784
+P + PA P P P PK E SP + +
Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483
Query: 785 ---------SFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQA-TTPK--ATEEPEDV 832
+ E + + + EP +P P + A TTPK A P++
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543
Query: 833 RSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQ 892
+ T E P +E++ +K + E + P +
Sbjct: 544 APTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTPEKPAP 601
Query: 893 SACFE----APDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPK 948
+ E P++ T + P+E + ++ + + EP+ PK
Sbjct: 602 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661
Query: 949 VTSRCIDS-------KEPIERPEEKPK---------KEGFIRSSEGPKPEKVYKSKSETR 992
T+ KEP +KP KE + + P P + T
Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721
Query: 993 WGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEK 1052
P P++ + +K+P K+ KE + T KP
Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP--KELAPTTTKGPTSTTSDKPAP 779
Query: 1053 TEKKDLPPPPPP------PQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDT-EK 1105
T K+ P P P+ PAP P++ PP + + E T+ + P + T E
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 1106 PLEP----VSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKK 1161
EP + EP V T P + + +K +DL + P + K
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK-DKTTERDLRTTPETTTAAPKMTK 898
Query: 1162 ES 1163
E+
Sbjct: 899 ET 900
Score = 44.7 bits (104), Expect = 0.001
Identities = 143/852 (16%), Positives = 254/852 (29%), Gaps = 99/852 (11%)
Query: 350 SEDQGSKASENNENKKETDEVSNTKS-----SSQIPAQPSVAKVPYGKGPSFNQERGTSS 404
++ + E + KET + T + +S++ A+P+ KGP+ + +
Sbjct: 252 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 311
Query: 405 HLPPPPKLLAQQHPPP----DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVE 460
P P + P P P P P +K E
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE----------------P 355
Query: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELE 520
+E +E E + K+P+P ++ +E
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 415
Query: 521 KEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKM 580
KE KE KE K+ +K E KE
Sbjct: 416 KEPTPTTPKE-------PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 581 KEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEA 640
+E KE K P EP +S + KE P T++ + + KE
Sbjct: 469 TTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527
Query: 641 TPVV---------HETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ 691
P E P + +P P K P ++ ++
Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 692 QQGVLPQTVPSQPSSST----VPPPPHRPL-YQPMQPHPQHLASMGFDPRWLMMQSYMDP 746
+ + P T P +P+ +T P P P P +P P P+ + +P
Sbjct: 588 PEKLAP-TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-------TPKAAAPNTPKEP 639
Query: 747 RMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHA------ISL 800
+ + P P PK +P + + E + + A +
Sbjct: 640 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTT 697
Query: 801 SEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKA 860
EP P P + T P +EP + A + PK
Sbjct: 698 KEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 755
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPS 920
+E + + S + + P + P + + P++ + E+ P
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Query: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPK 980
VS + T++P P P++ S EP + E KE + +++ P
Sbjct: 812 TTSEVSTPTT-TKEPTTIHKSPDESTPEL------SAEPTPKALENSPKEPGVPTTKTPA 864
Query: 981 PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAE 1040
K P ++ +++ +R +R + + KE ++ K
Sbjct: 865 ATK-----------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 913
Query: 1041 KVTEKVV------VKPEK--TEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTET 1092
T +V P K T K P + + P + K +T +
Sbjct: 914 ATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 973
Query: 1093 ATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAP----VVKEEKQPEKVISKDLVI 1148
KP + T+ P +P ST + + + +T P E P I++ ++
Sbjct: 974 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1033
Query: 1149 ERPRPDSRPAVK 1160
RP+ P K
Sbjct: 1034 TTTRPNQTPNSK 1045
Score = 43.9 bits (102), Expect = 0.002
Identities = 62/283 (21%), Positives = 98/283 (34%), Gaps = 22/283 (7%)
Query: 899 PDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKE 958
P + + P+E + ++S P+ + + + T+ EP+ K + KE
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTP-KE 370
Query: 959 PIERPEEKPKKEGFIRSSEGPK---PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGP 1015
P ++P + PK P K T P P++ + E P +
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTPKEPAPT 429
Query: 1016 IKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVK-PEKTEKKDLPPPPPPPQPPAPIQPQ 1074
K+P KE +K K K P T K+ P P P+ PAP +
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEPAPTTTK 487
Query: 1075 SVP-------PPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQ--- 1124
S P P A P + T ++P+ T P EP T +PA T +
Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKKPAPTTPKEPAP 545
Query: 1125 QTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPP 1167
T P K+P K+ P+ + KK + P
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 588
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 132 bits (331), Expect = 6e-30
Identities = 187/891 (20%), Positives = 306/891 (34%), Gaps = 87/891 (9%)
Query: 1479 KTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENV-LPPKRE 1537
++P N+ + + E E E S +E +E ++ ++ T+ K+ + RE
Sbjct: 135 RSPKPPNKKKTKKVIESEEITEEHS-VSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE 193
Query: 1538 IAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNE--RRSGPPSKSGKRGPFDDQPAGT 1595
+ K+ +R ++ PP SG N + + P + + + P T
Sbjct: 194 LQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 253
Query: 1596 TGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDP---KPGPKKPKEKVDALSQFDLN 1652
T + S T +K++T + +E K KEK + +
Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 313
Query: 1653 NYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDE--ERRKKEEQVIQVWN 1710
S + +V P++ G K+ E KE + +
Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 373
Query: 1711 KKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPL 1770
++ T+K P K+ A P P P + P +T P
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPA------------PTTTKEPAPTTPKEPAPTTTKEPA 421
Query: 1771 PATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITS 1830
P T P + P P + P + P P +P P + A +T A T+
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TTKEPAPTT 478
Query: 1831 SSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITA 1890
PA P + PA T A + + P P S+P A
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 538
Query: 1891 PTIPASAPTASVPLAPASASAPAPA----PTPVSAPNPAPPAPAQTQAQTHKPVQNPLQT 1946
PT SAPT +P + PAP P P + PAP P + T K P T
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK---EPAPT 595
Query: 1947 TSQSSKQPPPSIRLPSAQTPNGTDYVASGK-SIQTPQSHGTLTAELWDNKVAPPAVLNDI 2005
T++ K P + + P+ TP T K + TP+ T E K AP
Sbjct: 596 TTK--KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTT----- 644
Query: 2006 SKKLGPISPPQP-PSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGN 2064
++L P +P +P P+ P T +AP++ + + E T + AP +
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKE 703
Query: 2065 ENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKE------HKPGPIG 2118
P + + K P P ++ P+ +L+P KE KP P
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPK----------ELAPTTTKEPTSTTCDKPAP-- 751
Query: 2119 KERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAE 2178
+ K ++ P ++P+P T + T P T KE T + E
Sbjct: 752 --TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT--------TPKKPAPKE 801
Query: 2179 YGTNAKESVTDYTT--PSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSL 2236
+ T T+ P+ + P A K P P T P T + S+
Sbjct: 802 LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT 861
Query: 2237 TSVPPTTFSLT-------FKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPS 2289
T+ PTT + E KA ENSP +E G P T T ++++A +
Sbjct: 862 TTKEPTTIHKSPDESTPELSAEPTPKALENSP--KEPGVPTTKTPAATKPEMTTTAKDKT 919
Query: 2290 T---ANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPP 2337
T ++ + P++ + T T + + T++ T +TT P
Sbjct: 920 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 970
Score = 115 bits (289), Expect = 5e-25
Identities = 191/922 (20%), Positives = 309/922 (33%), Gaps = 93/922 (10%)
Query: 1401 AADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPR------FRRLREREAASKSNEVVA 1454
AA++ K + D + R +++ +PP D+ F+ + ++ N+V
Sbjct: 189 AANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST 248
Query: 1455 VPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERD-- 1512
P T +P+N + N D S + S E E++ N++ D
Sbjct: 249 SPKITTA-----KPINPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGK 301
Query: 1513 EKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRN 1572
EK + Q++ K L P ++ + PK+ GP
Sbjct: 302 EKTTSAKETQSIEKTSAKDLAPTSKVLAKP-----------------TPKAETTTKGPAL 344
Query: 1573 ERRSGPPSKSGKRGPFDDQPAGTTGVD----LINGSSAHHQEGVPNGTGQKNSKDSTGKK 1628
P + K +PA TT + I + +E P T +
Sbjct: 345 TTPKEPTPTTPK------EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 398
Query: 1629 REDPKPGPKKPKEKVDALSQFDL-NNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSK 1687
+P P PKE ++ S P T + P + +
Sbjct: 399 TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE--PAPTTP 456
Query: 1688 KQQKRLQDEERRKKEEQVIQVWNKK---NANEKGRSQTSKLPPRFAKKQATGIQQAQSSA 1744
K+ +E ++ K+ A +K T K P K+ + S
Sbjct: 457 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 516
Query: 1745 SVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPAS 1804
+ P + P+T+ S P +T P P T P + P P +T P + P P +
Sbjct: 517 TTPKEPA----PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 572
Query: 1805 PLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPIL 1864
P P + A A T AP + P P + P + L + L
Sbjct: 573 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Query: 1865 ASALASTSAPTPAPAASSPAAPVITAPTIPAS-APTASVPLAPASASAPAPA----PTPV 1919
A APT P +P P PT P APT AP + PAP P P
Sbjct: 633 APTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 691
Query: 1920 SAPNPAPPAPAQTQAQTHK-----PVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVAS 1974
+ PAP P +T T K ++ P TT K+P P P+ T T
Sbjct: 692 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTT-TKEPTSTTCD 747
Query: 1975 GKSIQTPQSHGTLT----AELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSF 2030
+ TP+ T A + AP L +P P + T+
Sbjct: 748 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 807
Query: 2031 GSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQ-- 2088
S+ K + E T + AP + P + ++ P ++
Sbjct: 808 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 867
Query: 2089 ---KQPRAGPIKAQKLPDLSPVENKEHKPG-PIGK-ERSLKNRKVKDAQQVEPEGQEKPS 2143
K P + P +EN +PG P K + K A+ E + +
Sbjct: 868 TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 927
Query: 2144 PATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDY---TTPSSSLPNT 2200
P T + P TKET +E +TE + I+ ++ + + + T + T +++L
Sbjct: 928 PETTTAA-PKMTKETATTTEKTTE--SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 984
Query: 2201 VATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENS 2260
V T + T + N P P ++ S + T P K S +K +
Sbjct: 985 VTTTKKTITTTEIMNKPEETAKP---KDRATNSKATTPKPQKPTKAPKKPTSTKKP-KTM 1040
Query: 2261 PNVRE-KGSP----VTSTAPPI 2277
P VR+ K +P +TST P +
Sbjct: 1041 PRVRKPKTTPTPRKMTSTMPEL 1062
Score = 60.8 bits (146), Expect = 2e-08
Identities = 82/380 (21%), Positives = 135/380 (35%), Gaps = 47/380 (12%)
Query: 801 SEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKA 860
S P P ++ ++TT ++ + P +++ ++ E+IT +SV NQ
Sbjct: 112 SPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ------- 164
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPS 920
ESS + S ++ ++ A N+ QK L ++ +
Sbjct: 165 ----ESSSSSSSSSSSSTIRKIKSSKNSAANREL------QKKLKVKDNKKNRTKKKPTP 214
Query: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPK----VTSRCIDSKEPIE-RPEEKPKKEGFIRS 975
+ V + D + + P + TS I + +PI RP P + +
Sbjct: 215 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 274
Query: 976 SEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKE 1035
S E ++K T + S++ +E+ + + I+K +D+
Sbjct: 275 SLTVNKETTVETKETTTTNKQTSTDGKEKTTS--AKETQSIEKTSAKDL----------- 321
Query: 1036 GEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPP--PIQPEAEKFPST--E 1091
KV K K E T K P P P P +P S P P + P+T E
Sbjct: 322 -APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE 380
Query: 1092 TATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERP 1151
A K + T P EP T EPA T + AP +E P S + P
Sbjct: 381 PAPTTTKSAPTT--PKEPAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKEP 435
Query: 1152 RPDS--RPAVKKESTLPPRT 1169
P + +PA P T
Sbjct: 436 APTTPKKPAPTTPKEPAPTT 455
Score = 55.8 bits (133), Expect = 6e-07
Identities = 153/842 (18%), Positives = 275/842 (32%), Gaps = 96/842 (11%)
Query: 403 SSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERA 462
SS PPP +Q +++ P P +K+ V + +EI ++ +++ S++ +
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRS-PKPPNKKKTKK-VIESEEITEEHSVSENQESSSSSSS 172
Query: 463 RKRREEEERRMEEQRKAACAE---KLKRLDEKLGILEKQPSPEE--IREREREKEREREK 517
+ + AA E KLK D K +K+P+P+ + E + K
Sbjct: 173 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 232
Query: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ--EKEKELERQKEKEK 575
+ + + + K + KE KE +E ++
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 292
Query: 576 ELQKMKEQEKECELEKEREKLEEK----IEPREPNLEPMVEKQESEN-----SCNKEEEP 626
Q + +++ KE + +E+ + P L K E+ + KE P
Sbjct: 293 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 352
Query: 627 VFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ 686
++ ++ + KE TP ++ P + +P P K P ++ ++
Sbjct: 353 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPTTTKEPAPTTPKE 411
Query: 687 WQQQQQQGVLPQTVPSQPSSSTVPPP--PHRPL-YQPMQPHPQHLASMGFDPRWLMMQSY 743
+ P T S P++ P P P +P P +P P P+ +
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-------TPKEPTPTTP 464
Query: 744 MDPRMMSGRPAMDIP---------------PIHPGMIPPKPLMRRDQMEGSPNSSE---- 784
+P + PA P P P PK E SP + +
Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524
Query: 785 ---------SFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQA-TTPK--ATEEPEDV 832
+ E + + + EP +P P + A TTPK A P++
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584
Query: 833 RSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQ 892
+ T E P +E++ +K + E + P +
Sbjct: 585 APTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTPEKPAP 642
Query: 893 SACFE----APDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPK 948
+ E P++ T + P+E + ++ + + EP+ PK
Sbjct: 643 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702
Query: 949 VTSRCIDS-------KEPIERPEEKPK---------KEGFIRSSEGPKPEKVYKSKSETR 992
T+ KEP +KP KE + + P P + T
Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762
Query: 993 WGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEK 1052
P P++ + +K+P K+ KE + T KP
Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP--KELAPTTTKGPTSTTSDKPAP 820
Query: 1053 TEKKDLPPPPPP------PQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDT-EK 1105
T K+ P P P+ PAP P++ PP + + E T+ + P + T E
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 1106 PLEP----VSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKK 1161
EP + EP V T P + + +K +DL + P + K
Sbjct: 881 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK-DKTTERDLRTTPETTTAAPKMTK 939
Query: 1162 ES 1163
E+
Sbjct: 940 ET 941
Score = 44.7 bits (104), Expect = 0.001
Identities = 143/852 (16%), Positives = 254/852 (29%), Gaps = 99/852 (11%)
Query: 350 SEDQGSKASENNENKKETDEVSNTKS-----SSQIPAQPSVAKVPYGKGPSFNQERGTSS 404
++ + E + KET + T + +S++ A+P+ KGP+ + +
Sbjct: 293 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 352
Query: 405 HLPPPPKLLAQQHPPP----DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVE 460
P P + P P P P P +K E
Sbjct: 353 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE----------------P 396
Query: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELE 520
+E +E E + K+P+P ++ +E
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 456
Query: 521 KEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKM 580
KE KE KE K+ +K E KE
Sbjct: 457 KEPTPTTPKE-------PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 509
Query: 581 KEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEA 640
+E KE K P EP +S + KE P T++ + + KE
Sbjct: 510 TTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568
Query: 641 TPVV---------HETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ 691
P E P + +P P K P ++ ++
Sbjct: 569 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 692 QQGVLPQTVPSQPSSST----VPPPPHRPL-YQPMQPHPQHLASMGFDPRWLMMQSYMDP 746
+ + P T P +P+ +T P P P P +P P P+ + +P
Sbjct: 629 PEKLAP-TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-------TPKAAAPNTPKEP 680
Query: 747 RMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHA------ISL 800
+ + P P PK +P + + E + + A +
Sbjct: 681 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTT 738
Query: 801 SEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKA 860
EP P P + T P +EP + A + PK
Sbjct: 739 KEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 796
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPS 920
+E + + S + + P + P + + P++ + E+ P
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Query: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPK 980
VS + T++P P P++ S EP + E KE + +++ P
Sbjct: 853 TTSEVSTPTT-TKEPTTIHKSPDESTPEL------SAEPTPKALENSPKEPGVPTTKTPA 905
Query: 981 PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAE 1040
K P ++ +++ +R +R + + KE ++ K
Sbjct: 906 ATK-----------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 954
Query: 1041 KVTEKVV------VKPEK--TEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTET 1092
T +V P K T K P + + P + K +T +
Sbjct: 955 ATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 1014
Query: 1093 ATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAP----VVKEEKQPEKVISKDLVI 1148
KP + T+ P +P ST + + + +T P E P I++ ++
Sbjct: 1015 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1074
Query: 1149 ERPRPDSRPAVK 1160
RP+ P K
Sbjct: 1075 TTTRPNQTPNSK 1086
Score = 43.9 bits (102), Expect = 0.002
Identities = 62/283 (21%), Positives = 98/283 (34%), Gaps = 22/283 (7%)
Query: 899 PDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKE 958
P + + P+E + ++S P+ + + + T+ EP+ K + KE
Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTP-KE 411
Query: 959 PIERPEEKPKKEGFIRSSEGPK---PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGP 1015
P ++P + PK P K T P P++ + E P +
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTPKEPAPT 470
Query: 1016 IKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVK-PEKTEKKDLPPPPPPPQPPAPIQPQ 1074
K+P KE +K K K P T K+ P P P+ PAP +
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEPAPTTTK 528
Query: 1075 SVP-------PPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQ--- 1124
S P P A P + T ++P+ T P EP T +PA T +
Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKKPAPTTPKEPAP 586
Query: 1125 QTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPP 1167
T P K+P K+ P+ + KK + P
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 629
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 127 bits (319), Expect = 2e-28
Identities = 136/611 (22%), Positives = 226/611 (36%), Gaps = 39/611 (6%)
Query: 1748 PLASAPLPPSTSASVPASTSAPLPATLTPV--PASTSAPVPASTLAPVLASTSAPVPASP 1805
P + P PP+T+ + P T+ P P T TP+ PAST+ P +T +P +T+ P P +
Sbjct: 1479 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTT 1538
Query: 1806 -----LAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASAS 1860
P++ S + P +T + T+++ P P+P + +P ++T
Sbjct: 1539 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598
Query: 1861 IPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAP-ASASAPAPAPTPV 1919
+ +T+ P P S P IT PT + P + P P + + P P TP
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP- 1657
Query: 1920 SAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQ 1979
S P P+P T T P P + + P ++ PS T + +
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS 1717
Query: 1980 TPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGA 2039
T T + P+ L P + P + + +T +P S
Sbjct: 1718 TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTT 1777
Query: 2040 KNGQESGLEIGTDTIQFGAPASN--GNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIK 2097
L T + G P + G + E++ + + G +
Sbjct: 1778 PTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLG 1837
Query: 2098 AQKLPDLSP---VENKEHKPGPIGKERSLKNRK--------VKDAQQVEPEGQEKPSPAT 2146
+ D+S +N++ KPG + N + V + E P+P T
Sbjct: 1838 QTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPT 1897
Query: 2147 VRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPS-SSLPNTVATNN 2205
T P+TT T V+ T GT ++ T +VT TP+ + P T
Sbjct: 1898 ---TTPITT--TTTVTPTPTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITT 1949
Query: 2206 TKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVRE 2265
T T V P P P I ++++T P T + T +P
Sbjct: 1950 T----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2005
Query: 2266 KGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSS 2325
G+ T T PI T ++ P+ + + + P +VTPT + +G T TT+
Sbjct: 2006 TGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061
Query: 2326 LSTKSTTTSDP 2336
++T +T T P
Sbjct: 2062 ITTTTTVTPTP 2072
Score = 121 bits (304), Expect = 9e-27
Identities = 152/751 (20%), Positives = 246/751 (32%), Gaps = 100/751 (13%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAST-LAPV 1793
TG Q ++ P P T P +T T+TP P T P +T +
Sbjct: 3593 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3652
Query: 1794 LASTSAPVPASPLAPVSASASVSASV-PASTSAAAITSSSAPASAPA---PTPILASVST 1849
T P P P + + + +V P T T ++ P + PTP T
Sbjct: 3653 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712
Query: 1850 PASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPTAS-----VP 1903
P + I + ++ T PTP + P+ T T+ P PT + P
Sbjct: 3713 PTTTPITTTTTV---------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763
Query: 1904 LAPASASAPAPAPTPVSAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQPP 1955
+ + P P PT P P P P T QT P P+ TT+ + P
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPT 3821
Query: 1956 PSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPP 2015
P+ QTP T + TP GT T + + G +P
Sbjct: 3822 PT----GTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3875
Query: 2016 QPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEK 2075
P + T+ P+ G + + I T T P G + ++
Sbjct: 3876 TTPITTT-----TTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTT 3928
Query: 2076 SADKIPEPKEQRQKQPRAGPIKAQKL--PDLSPVENKEHKPGPIGKERSLKNRKVKDAQQ 2133
+ P P + P PI P +P + PI ++
Sbjct: 3929 TT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----- 3982
Query: 2134 VEPEGQEKPSPATVRSTDPVTTKETKAVSEM--STEIGTMISVSSAEYGTNAKESVTDYT 2191
P G + P+ + +T VT T ++ +T I T +V+ T + T
Sbjct: 3983 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040
Query: 2192 TPSSSLPNTVATNNTKMEDTL-------VNNVPLPNTLPLPKRETIQQSSSLTSVPPTTF 2244
T ++++ T T+ T V P P P I ++++T P T
Sbjct: 4041 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4100
Query: 2245 SLTFKMESARKAWENSPNVREKGS------PVTSTAPPIATGVSSSASGPSTANYNSFSS 2298
+ T +P G+ P+T+T T + P+T + ++
Sbjct: 4101 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160
Query: 2299 ASMPQIPVASV-----------------TPTASLSGAGTYTTSSLSTKSTTTSDPPNICK 2341
+ P + TPT + +G T+T+++ + TT++ PP
Sbjct: 4161 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPE--S 4218
Query: 2342 VKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQ 2401
PQ +++S P + LS +P P + ++ +A P TS
Sbjct: 4219 STPQTSRSTSSPLTESTTLLSTLP---------PAIEMTSTAPPSTPTAPTTTS----GG 4265
Query: 2402 HARLAPPSLAQQQGFQPGLSQPTSVQQIPIP 2432
H PPS P T P P
Sbjct: 4266 HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP 4296
Score = 120 bits (302), Expect = 1e-26
Identities = 155/681 (22%), Positives = 256/681 (37%), Gaps = 101/681 (14%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPV--PASTSAPVPASTLAP 1792
T I S+ ++PP + P PP+T+ + P T+ P P T TP+ P ST+ P +T +P
Sbjct: 1506 TPITPPASTTTLPP-TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564
Query: 1793 VLASTSAP----VPASPLAPVSASASVSASVPASTSA----AAITSSSAPASAPAPTPIL 1844
+T+ P P+ P + +++ + P T+ T++ P + P+P P
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP-PTT 1623
Query: 1845 ASVSTPASVTILASASIPILASALASTSAPTPAPA-------------------ASSPAA 1885
++ P S T L + P +T PT P+ ++P++
Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683
Query: 1886 PVITAP-------TIPASAPTASVPL----APASASAPAPAPTPVSAPNP-APPAPAQTQ 1933
P+ T P T P+ T S P+ P+S + P+P PT ++ P+P P+P T
Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743
Query: 1934 AQTHKP--VQNPLQTTSQSSKQPPPSIRLPSAQTP--------NGTDYVASGKSIQTPQS 1983
T P +PL TT PP+ S TP N T ++ SGK P
Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGK----PNF 1799
Query: 1984 H--GTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPL---TSFGSAPSSEG 2038
H G T + D V P +IS + + P P + + + S G +E
Sbjct: 1800 HKPGGDTELIGD--VCGPGWAANISCR-ATMYPDVP--IGQLGQTVVCDVSVGLICKNED 1854
Query: 2039 AKNG----------QESGLEIGTDTIQFGAPASNGNENEVVPVLS--EKSADKIPEPKEQ 2086
K G E ++ Q + EN P + + P P
Sbjct: 1855 QKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPT 1914
Query: 2087 RQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSP 2144
+ P PI P +P + PI ++ P G + P+
Sbjct: 1915 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTPTGTQTPTT 1967
Query: 2145 ATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVA 2202
+ +T VT T ++ +T I T +V+ T + T T ++++ T
Sbjct: 1968 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027
Query: 2203 TNNTK-------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARK 2255
T+ T V P P P I ++++T P T + T
Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2087
Query: 2256 AWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASL 2315
+P G+ T T PI T ++ P+ + + + P +VTPT +
Sbjct: 2088 TTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2143
Query: 2316 SGAGTYTTSSLSTKSTTTSDP 2336
+G T TT+ ++T +T T P
Sbjct: 2144 TGTQTPTTTPITTTTTVTPTP 2164
Score = 119 bits (298), Expect = 4e-26
Identities = 134/632 (21%), Positives = 214/632 (33%), Gaps = 66/632 (10%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAST-LAPV 1793
TG Q ++ P P T P +T T+TP P T P +T +
Sbjct: 1914 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1973
Query: 1794 LASTSAPVPASPLAPVSASASVSASV-PASTSAAAITSSSAP---ASAPAPTPILASVST 1849
T P P P + + + +V P T T ++ P + PTP T
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033
Query: 1850 PASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPT-----ASVP 1903
P + I + ++ T PTP + P+ T T+ P PT + P
Sbjct: 2034 PTTTPITTTTTV---------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2084
Query: 1904 LAPASASAPAPAPTPVSAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQPP 1955
+ + P P PT P P P P T QT P P+ TT+ + P
Sbjct: 2085 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPT 2142
Query: 1956 PSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPP 2015
P+ QTP T + TP GT T + + G +P
Sbjct: 2143 PT----GTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPT 2196
Query: 2016 QPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEK 2075
P + T+ P+ G + + I T T P G + ++
Sbjct: 2197 TTPITTT-----TTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT-T 2248
Query: 2076 SADKIPEPKEQRQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQ 2133
+ P P + P PI P +P + PI ++
Sbjct: 2249 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPT 2301
Query: 2134 VEPEGQEKPSPATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTDYT 2191
P G + P+ + +T VT T ++ +T I T +V+ T + T
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361
Query: 2192 TPSSSLPNTVATNNTK-------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTF 2244
T ++++ T T+ T V P P P I ++++T P T
Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421
Query: 2245 SLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQI 2304
+ T +P G+ T T PI T ++ P+ + + + P
Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTPIT 2477
Query: 2305 PVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
+VTPT + +G T TT+ ++T +T T P
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2509
Score = 115 bits (289), Expect = 5e-25
Identities = 132/616 (21%), Positives = 210/616 (34%), Gaps = 70/616 (11%)
Query: 1753 PLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAST-LAPVLASTSAPVPASPLAPVSA 1811
P P T P +T T+TP P T P +T + T P P P +
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968
Query: 1812 SASVSASV-PASTSAAAITSSSAPASA-----PAPTPILASVSTPASVTILASASIPILA 1865
+ + +V P T T ++ P + P PTP TP + I + ++
Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTV---- 2022
Query: 1866 SALASTSAPTPAPAASSPAAPVITAPTI-PASAPT-----ASVPLAPASASAPAPAPTPV 1919
T PTP + P+ T T+ P PT + P+ + P P PT
Sbjct: 2023 -----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2077
Query: 1920 SAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDY 1971
P P P P T QT P P+ TT+ + P P+ QTP T
Sbjct: 2078 QTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPT----GTQTPTTTPI 2131
Query: 1972 VASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFG 2031
+ TP GT T + + G +P P + T+
Sbjct: 2132 TTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVT 2184
Query: 2032 SAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQP 2091
P+ G + + I T T P G + ++ + P P + P
Sbjct: 2185 PTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTP 2241
Query: 2092 RAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRS 2149
PI P +P + PI ++ P G + P+ + +
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTPTGTQTPTTTPITT 2294
Query: 2150 TDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTK 2207
T VT T ++ +T I T +V+ T + T T ++++ T T+
Sbjct: 2295 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2354
Query: 2208 -------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENS 2260
T V P P P I ++++T P T + T +
Sbjct: 2355 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2414
Query: 2261 PNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGT 2320
P G+ T T PI T ++ P+ + + + P +VTPT + +G T
Sbjct: 2415 PTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2470
Query: 2321 YTTSSLSTKSTTTSDP 2336
TT+ ++T +T T P
Sbjct: 2471 PTTTPITTTTTVTPTP 2486
Score = 114 bits (286), Expect = 1e-24
Identities = 134/634 (21%), Positives = 215/634 (33%), Gaps = 70/634 (11%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVL 1794
TG Q ++ P P T P +T P+ T T P T T P+
Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPIT 2316
Query: 1795 ASTS---APVPASPLAPVSASASVSASV-PASTSAAAITSSSAP---ASAPAPTPILASV 1847
+T+ P P P + + + +V P T T ++ P + PTP
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376
Query: 1848 STPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPT-----AS 1901
TP + I + ++ T PTP + P+ T T+ P PT +
Sbjct: 2377 QTPTTTPITTTTTV---------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427
Query: 1902 VPLAPASASAPAPAPTPVSAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQ 1953
P+ + P P PT P P P P T QT P P+ TT+ +
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 2485
Query: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS 2013
P P+ QTP T + TP GT T + + G +
Sbjct: 2486 PTPT----GTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQT 2539
Query: 2014 PPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLS 2073
P P + T+ P+ G + + I T T P G + ++
Sbjct: 2540 PTTTPITTT-----TTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592
Query: 2074 EKSADKIPEPKEQRQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDA 2131
+ P P + P PI P +P + PI ++
Sbjct: 2593 -TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------T 2644
Query: 2132 QQVEPEGQEKPSPATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTD 2189
P G + P+ + +T VT T ++ +T I T +V+ T + T
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2704
Query: 2190 YTTPSSSLPNTVATNNTK-------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPT 2242
T ++++ T T+ T V P P P I ++++T P
Sbjct: 2705 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2764
Query: 2243 TFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMP 2302
T + T +P G+ T T PI T ++ P+ + + + P
Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTP 2820
Query: 2303 QIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
+VTPT + +G T TT+ ++T +T T P
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2854
Score = 114 bits (286), Expect = 1e-24
Identities = 134/634 (21%), Positives = 215/634 (33%), Gaps = 70/634 (11%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVL 1794
TG Q ++ P P T P +T P+ T T P T T P+
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPIT 2684
Query: 1795 ASTS---APVPASPLAPVSASASVSASV-PASTSAAAITSSSAP---ASAPAPTPILASV 1847
+T+ P P P + + + +V P T T ++ P + PTP
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2744
Query: 1848 STPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPT-----AS 1901
TP + I + ++ T PTP + P+ T T+ P PT +
Sbjct: 2745 QTPTTTPITTTTTV---------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795
Query: 1902 VPLAPASASAPAPAPTPVSAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQ 1953
P+ + P P PT P P P P T QT P P+ TT+ +
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 2853
Query: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS 2013
P P+ QTP T + TP GT T + + G +
Sbjct: 2854 PTPT----GTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQT 2907
Query: 2014 PPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLS 2073
P P + T+ P+ G + + I T T P G + ++
Sbjct: 2908 PTTTPITTT-----TTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960
Query: 2074 EKSADKIPEPKEQRQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDA 2131
+ P P + P PI P +P + PI ++
Sbjct: 2961 -TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------T 3012
Query: 2132 QQVEPEGQEKPSPATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTD 2189
P G + P+ + +T VT T ++ +T I T +V+ T + T
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072
Query: 2190 YTTPSSSLPNTVATNNTK-------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPT 2242
T ++++ T T+ T V P P P I ++++T P
Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3132
Query: 2243 TFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMP 2302
T + T +P G+ T T PI T ++ P+ + + + P
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTP 3188
Query: 2303 QIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
+VTPT + +G T TT+ ++T +T T P
Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3222
Score = 114 bits (286), Expect = 1e-24
Identities = 134/634 (21%), Positives = 215/634 (33%), Gaps = 70/634 (11%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVL 1794
TG Q ++ P P T P +T P+ T T P T T P+
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPIT 3052
Query: 1795 ASTS---APVPASPLAPVSASASVSASV-PASTSAAAITSSSAP---ASAPAPTPILASV 1847
+T+ P P P + + + +V P T T ++ P + PTP
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112
Query: 1848 STPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPT-----AS 1901
TP + I + ++ T PTP + P+ T T+ P PT +
Sbjct: 3113 QTPTTTPITTTTTV---------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163
Query: 1902 VPLAPASASAPAPAPTPVSAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQ 1953
P+ + P P PT P P P P T QT P P+ TT+ +
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 3221
Query: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS 2013
P P+ QTP T + TP GT T + + G +
Sbjct: 3222 PTPT----GTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQT 3275
Query: 2014 PPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLS 2073
P P + T+ P+ G + + I T T P G + ++
Sbjct: 3276 PTTTPITTT-----TTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328
Query: 2074 EKSADKIPEPKEQRQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDA 2131
+ P P + P PI P +P + PI ++
Sbjct: 3329 -TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------T 3380
Query: 2132 QQVEPEGQEKPSPATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTD 2189
P G + P+ + +T VT T ++ +T I T +V+ T + T
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3440
Query: 2190 YTTPSSSLPNTVATNNTK-------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPT 2242
T ++++ T T+ T V P P P I ++++T P
Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3500
Query: 2243 TFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMP 2302
T + T +P G+ T T PI T ++ P+ + + + P
Sbjct: 3501 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTP 3556
Query: 2303 QIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
+VTPT + +G T TT+ ++T +T T P
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590
Score = 114 bits (286), Expect = 1e-24
Identities = 134/634 (21%), Positives = 215/634 (33%), Gaps = 70/634 (11%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVL 1794
TG Q ++ P P T P +T P+ T T P T T P+
Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPIT 3420
Query: 1795 ASTS---APVPASPLAPVSASASVSASV-PASTSAAAITSSSAP---ASAPAPTPILASV 1847
+T+ P P P + + + +V P T T ++ P + PTP
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3480
Query: 1848 STPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPT-----AS 1901
TP + I + ++ T PTP + P+ T T+ P PT +
Sbjct: 3481 QTPTTTPITTTTTV---------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3531
Query: 1902 VPLAPASASAPAPAPTPVSAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQ 1953
P+ + P P PT P P P P T QT P P+ TT+ +
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 3589
Query: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS 2013
P P+ QTP T + TP GT T + + G +
Sbjct: 3590 PTPT----GTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQT 3643
Query: 2014 PPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLS 2073
P P + T+ P+ G + + I T T P G + ++
Sbjct: 3644 PTTTPITTT-----TTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696
Query: 2074 EKSADKIPEPKEQRQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDA 2131
+ P P + P PI P +P + PI ++
Sbjct: 3697 -TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------T 3748
Query: 2132 QQVEPEGQEKPSPATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTD 2189
P G + P+ + +T VT T ++ +T I T +V+ T + T
Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3808
Query: 2190 YTTPSSSLPNTVATNNTK-------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPT 2242
T ++++ T T+ T V P P P I ++++T P
Sbjct: 3809 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3868
Query: 2243 TFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMP 2302
T + T +P G+ T T PI T ++ P+ + + + P
Sbjct: 3869 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTP 3924
Query: 2303 QIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
+VTPT + +G T TT+ ++T +T T P
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3958
Score = 110 bits (275), Expect = 2e-23
Identities = 87/360 (24%), Positives = 140/360 (38%), Gaps = 34/360 (9%)
Query: 1751 SAPLPPSTSASVPASTSAPLPATLTPVP--ASTSAPVPASTLAPVLASTSAPVP-ASPLA 1807
+ P PP+T+ S P +++ LP T TP P +T+ P P +T +P + +T+ P P +P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 1808 PVSASA----SVSASVPASTSAAAITSSSAP---ASAPAPT-----PILASVSTPASVTI 1855
P+S + + + S P +T + T+ S P + P PT P ++ PAS T
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 1856 LASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPA 1915
L + P + +T+ P P S P IT PT + P + P P + + P
Sbjct: 1517 LPPTTTP--SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574
Query: 1916 PTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASG 1975
T S P P+P T P P T+ ++ PP + P TP
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP--------- 1625
Query: 1976 KSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPS 2035
I P S TL +PP P + P PP+ + + P+T+ + P
Sbjct: 1626 --ITPPTSTTTLPP---TTTPSPPPTTTTTPP---PTTTPSPPTTTTPSPPITTTTTPPP 1677
Query: 2036 SEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGP 2095
+ + + T T+ +P + + + P P P P
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTP 1737
Score = 110 bits (275), Expect = 2e-23
Identities = 144/647 (22%), Positives = 221/647 (34%), Gaps = 81/647 (12%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVL 1794
TG Q ++ P P T P +T P+ T T P T T P+
Sbjct: 3731 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPIT 3788
Query: 1795 ASTS---APVPASPLAPVSASASVSASV-PASTSAAAITSSSAP---ASAPAPTPILASV 1847
+T+ P P P + + + +V P T T ++ P + PTP
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3848
Query: 1848 STPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPT-----AS 1901
TP + I + ++ T PTP + P+ T T+ P PT +
Sbjct: 3849 QTPTTTPITTTTTV---------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3899
Query: 1902 VPLAPASASAPAPAPTPVSAPNPAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQ 1953
P+ + P P PT P P P P T QT P P+ TT+ +
Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 3957
Query: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS 2013
P P+ QTP T + TP GT T + + G +
Sbjct: 3958 PTPT----GTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQT 4011
Query: 2014 PPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLS 2073
P P + T+ P+ G + + I T T P G + ++
Sbjct: 4012 PTTTPITTT-----TTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4064
Query: 2074 EKSADKIPEPKEQRQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDA 2131
+ P P + P PI P +P + PI ++
Sbjct: 4065 -TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------T 4116
Query: 2132 QQVEPEGQEKPSPATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAK-ESVT 2188
P G + P+ + +T VT T ++ +T I T +V+ T + + T
Sbjct: 4117 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4176
Query: 2189 DYTTPSSSLPNTVATNNTKMEDTLVNNVP---LPNTLPLPKRETIQQSSSLTSVPPTTFS 2245
TT ++ P T T + P L + P P+ T Q S S +S P T S
Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSS--PLTES 4234
Query: 2246 LTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIP 2305
T + + A E +TSTAPP ++ SG T + ++ S P P
Sbjct: 4235 TTL-LSTLPPAIE-----------MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTP 4282
Query: 2306 VASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSL 2352
T S A T +T +T S T P + P ++T+ L
Sbjct: 4283 TRGT--TTGSSSAPTPSTVQTTTTSAWTPTPTPLS--TPSIIRTTGL 4325
Score = 109 bits (272), Expect = 4e-23
Identities = 128/612 (20%), Positives = 210/612 (34%), Gaps = 68/612 (11%)
Query: 1757 STSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTS---APVPASPLAPVSASA 1813
+T+ + T+ P+ T T P T T P+ +T+ P P P +
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947
Query: 1814 SVSASV-PASTSAAAITSSSAP---ASAPAPTPILASVSTPASVTILASASIPILASALA 1869
+ + +V P T T ++ P + PTP TP + I + ++
Sbjct: 1948 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------- 1999
Query: 1870 STSAPTPAPAASSPAAPVITAPTI-PASAPT-----ASVPLAPASASAPAPAPTPVSAPN 1923
T PTP + P+ T T+ P PT + P+ + P P PT P
Sbjct: 2000 -TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2058
Query: 1924 PAP--------PAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASG 1975
P P P T QT P P+ TT+ + P P+ QTP T +
Sbjct: 2059 TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTT 2112
Query: 1976 KSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPS 2035
TP GT T + + G +P P + T+ P+
Sbjct: 2113 TVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTPT 2165
Query: 2036 SEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGP 2095
G + + I T T P G + ++ + P P + P P
Sbjct: 2166 PTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTP 2222
Query: 2096 IKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPV 2153
I P +P + PI ++ P G + P+ + +T V
Sbjct: 2223 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTTTV 2275
Query: 2154 TTKETKAVSE--MSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTK---- 2207
T T ++ +T I T +V+ T + T T ++++ T T+
Sbjct: 2276 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2335
Query: 2208 ---MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVR 2264
T V P P P I ++++T P T + T +P
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395
Query: 2265 EKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTS 2324
G+ T T PI T ++ P+ + + + P +VTPT + +G T TT+
Sbjct: 2396 PTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451
Query: 2325 SLSTKSTTTSDP 2336
++T +T T P
Sbjct: 2452 PITTTTTVTPTP 2463
Score = 92.4 bits (228), Expect = 6e-18
Identities = 120/577 (20%), Positives = 192/577 (33%), Gaps = 75/577 (12%)
Query: 1771 PATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITS 1830
P T+T +T P P +T +T P P P +T IT+
Sbjct: 1882 PTTMTTT--TTENPTPPTTTPITTTTTVTPTPTP----------TGTQTPTTTP---ITT 1926
Query: 1831 SSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITA 1890
++ P PT +TP + T +T PTP P +
Sbjct: 1927 TTTVTPTPTPTGTQTPTTTPITTT---------------TTVTPTPTPTGTQ-------T 1964
Query: 1891 PTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQS 1950
PT T +V P P TP++ P P T QT P P+ TT+
Sbjct: 1965 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTV 2022
Query: 1951 SKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLG 2010
+ P P+ QTP T + TP GT T + + G
Sbjct: 2023 TPTPTPT----GTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTG 2076
Query: 2011 PISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVP 2070
+P P + T+ P+ G + + I T T P G +
Sbjct: 2077 TQTPTTTPITTT-----TTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTT 2129
Query: 2071 VLSEKSADKIPEPKEQRQKQPRAGPIKAQK--LPDLSPVENKEHKPGPIGKERSLKNRKV 2128
++ + P P + P PI P +P + PI ++
Sbjct: 2130 PIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV----- 2183
Query: 2129 KDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSE--MSTEIGTMISVSSAEYGTNAKES 2186
P G + P+ + +T VT T ++ +T I T +V+ T +
Sbjct: 2184 --TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2241
Query: 2187 VTDYTTPSSSLPNTVATNNTK-------MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSV 2239
T T ++++ T T+ T V P P P I ++++T
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2301
Query: 2240 PPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSA 2299
P T + T +P G+ T T PI T ++ P+ + +
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPTPTGTQTPT 2357
Query: 2300 SMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
+ P +VTPT + +G T TT+ ++T +T T P
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2394
Score = 68.9 bits (167), Expect = 7e-11
Identities = 104/463 (22%), Positives = 150/463 (32%), Gaps = 94/463 (20%)
Query: 1883 PAAPVITAPTIPASA----PTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHK 1938
P IT P+ P + PT++ L P + +P P T + P P+P T T
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPITTTTTPP 1449
Query: 1939 PVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLT-AELWDNKVA 1997
P P S ++ PP + P TP+ S + T T T + +
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509
Query: 1998 PPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFG 2057
PPA + L P + P PP+ + P T+ S P++
Sbjct: 1510 PPA----STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT--------------------- 1544
Query: 2058 APASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPI 2117
P + +P + S P P P P SP P I
Sbjct: 1545 TPITPPTSTTTLPPTTTPS----PPPTTTTTPPPTTTP---------SPPTTTTPSPPTI 1591
Query: 2118 GKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSA 2177
P PSP T +T P T T +T I S ++
Sbjct: 1592 --------------TTTTPPPTTTPSPPTTTTTTPPPT--TTPSPPTTTPITPPTSTTTL 1635
Query: 2178 EYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLT 2237
T T TTP + + T T P P T P SS +T
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP---------SSPIT 1686
Query: 2238 SVP-PTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSF 2296
+ P P T ++T SP SP+T+T P +T S P +
Sbjct: 1687 TTPSPPTTTMT----------TPSPTT-TPSSPITTTTTPSSTTTPS----PPPTTMTTP 1731
Query: 2297 SSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNI 2339
S + P P ++T T ++ S+ TTT PP+I
Sbjct: 1732 SPTTTPSPPTTTMT---------TLPPTTTSSPLTTTPLPPSI 1765
Score = 66.6 bits (161), Expect = 3e-10
Identities = 96/428 (22%), Positives = 140/428 (32%), Gaps = 80/428 (18%)
Query: 1828 ITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPV 1887
IT+ S P + P+P P S T L + P + +T PT P+ P
Sbjct: 1396 ITTPSPPTTTPSPPP--------TSTTTLPPTTTPSPPTTTTTTPPPTTTPS------PP 1441
Query: 1888 ITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTT 1947
IT T P T S P++ + P P+P P P P T + P TT
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPSP---PTTTPSPPTTTPSP-------PTTTT 1491
Query: 1948 SQSSKQPPPSIRLPSAQTPNGTDYVASGKSI---QTPQSHGTLTAELWDNKVAPPAVLND 2004
+ PPP+ PS T AS ++ TP T T P
Sbjct: 1492 T----TPPPT-TTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1546
Query: 2005 I-----SKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAP 2059
I + L P + P PP + P T+ S P++ TI P
Sbjct: 1547 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP----------SPPTITTTTP 1596
Query: 2060 ASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGK 2119
+ + P P P P LP + P P
Sbjct: 1597 PPTTTPSPPTTTTTTPPPTTTPSPP---TTTPITPPTSTTTLPPTT-------TPSP--- 1643
Query: 2120 ERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEY 2179
P P T + P TT + ++ +T T + S+
Sbjct: 1644 ----------------PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPT--TTPSSPI 1685
Query: 2180 GTNAKESVTDYTTPS-SSLPNT-VATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLT 2237
T T TTPS ++ P++ + T T T + P T P P ++++T
Sbjct: 1686 TTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745
Query: 2238 SVPPTTFS 2245
++PPTT S
Sbjct: 1746 TLPPTTTS 1753
Score = 58.9 bits (141), Expect = 7e-08
Identities = 54/223 (24%), Positives = 82/223 (36%), Gaps = 10/223 (4%)
Query: 2142 PSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTV 2201
PSP T +T P T T +T I S ++ T T TTP + +
Sbjct: 1523 PSPPTTTTTTPPPT--TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP 1580
Query: 2202 ATNNTKMEDTLVNNVPLPNTLPL-PKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENS 2260
T T T+ P P T P P T + T PPTT +T + +
Sbjct: 1581 PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640
Query: 2261 PN----VREKGSPVTSTAPPIATGVS---SSASGPSTANYNSFSSASMPQIPVASVTPTA 2313
P+ P T+ +PP T S ++ + P S + P P ++T +
Sbjct: 1641 PSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS 1700
Query: 2314 SLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSAS 2356
+ + T++ + STTT PP P T S P+ +
Sbjct: 1701 PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743
Score = 56.6 bits (135), Expect = 3e-07
Identities = 60/229 (26%), Positives = 86/229 (37%), Gaps = 58/229 (25%)
Query: 1740 AQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLAS--- 1796
A+ + S PP S+ S S S P + S L +TL P TS P++ AP S
Sbjct: 4207 AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGH 4266
Query: 1797 TSAPVPAS----PLAPVSASASVSASVPA-STSAAAITSSSAPASAPAPTPILASVST-- 1849
T +P P++ P P + + S+S P ST TS+ P P TP + +
Sbjct: 4267 TLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLR 4326
Query: 1850 --PASVTILA-----------------------------SASIPILASALASTSAPTPAP 1878
P+SV I S ++ + ST +PTP P
Sbjct: 4327 PYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTP 4386
Query: 1879 AASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPP 1927
+ S+P P+ P+S P S P P P P+ PP
Sbjct: 4387 SKSTPT------PSKPSSTP-----------SKPTPGTKPPECPDFDPP 4418
Score = 56.2 bits (134), Expect = 4e-07
Identities = 57/260 (21%), Positives = 94/260 (36%), Gaps = 56/260 (21%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPA--------------- 1779
TG Q ++ P P T P +T T+TP P
Sbjct: 4145 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTA 4204
Query: 1780 -----STSAPVPASTLAPVLASTSAPVPASP--LAPVSASASVSASVPASTSAAAITSSS 1832
+TS P P S+ STS+P+ S L+ + + ++++ P ST A T+S
Sbjct: 4205 PIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG 4264
Query: 1833 APASAPAPTPILASVSTPASVTILASASIPILASALASTSA---PTPAPAASSPAAPVIT 1889
+P P+ + TP T S+S P ++ +T++ PTP P ++
Sbjct: 4265 GHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTG 4324
Query: 1890 APTIPAS------------AP------------------TASVPLAPASASAPAPAPTPV 1919
P+S AP + S L + S P+ P+P
Sbjct: 4325 LRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPS-TPSPT 4383
Query: 1920 SAPNPAPPAPAQTQAQTHKP 1939
P+ + P P++ + KP
Sbjct: 4384 PTPSKSTPTPSKPSSTPSKP 4403
Score = 53.9 bits (128), Expect = 2e-06
Identities = 72/349 (20%), Positives = 113/349 (32%), Gaps = 35/349 (10%)
Query: 2136 PEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSS 2195
P PSP T + P TT + + T T + + T T P+S
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTT----------TPSPPTTTPITPPAS 1513
Query: 2196 SLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRET-IQQSSSLTSVPPTTFSLTFKMESAR 2254
+ T+ T T P P T P P T I +S T++PPTT
Sbjct: 1514 T--TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP--------- 1562
Query: 2255 KAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTAS 2314
P P T+ +PP T S P T + + P P + T
Sbjct: 1563 ---SPPPTTTTTPPPTTTPSPPTTTTPS-----PPTITTTTPPPTTTPSPPTTTTTTPPP 1614
Query: 2315 LSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPS-LIAQQQQ 2373
+ TT+ ++ ++TT+ PP P T+ P+ + + PS I
Sbjct: 1615 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT 1674
Query: 2374 NPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPI 2433
P S P+ T + +P + S P + P P
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Query: 2434 YAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPS 2482
P ++ P + + L ++ L P + P F S + P+
Sbjct: 1735 TTP----SPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779
Score = 46.6 bits (109), Expect = 3e-04
Identities = 52/224 (23%), Positives = 83/224 (37%), Gaps = 23/224 (10%)
Query: 2142 PSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTV 2201
PSP T + P T+ T + +T + ++ T +T TTP + +
Sbjct: 1399 PSPPTTTPSPPPTS--TTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 2202 ATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSP 2261
+ T P P T P P T + T PPTT + T + +P
Sbjct: 1457 PISTT--------TTPPPTTTPSPP-TTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507
Query: 2262 NVREKGS----PVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSG 2317
+ P T+ +PP T ++ P+T ++ P ++ PT + S
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTT---TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564
Query: 2318 AGTYT-----TSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSAS 2356
T T T++ S +TTT PP I P T S P+ +
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTT 1608
Score = 45.4 bits (106), Expect = 8e-04
Identities = 43/189 (22%), Positives = 67/189 (35%), Gaps = 27/189 (14%)
Query: 2172 ISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQ 2231
I+ S T + + T P ++ P+ T T T + P+ T P T
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 2232 QSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVS----SSASG 2287
S T+ PP T + SP P T+ +PP T + ++ S
Sbjct: 1456 PPISTTTTPPPTTT-------------PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502
Query: 2288 PSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQL 2347
P+T P P AS T + TT++ + TTT PP + P
Sbjct: 1503 PTTT----------PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1552
Query: 2348 QTSSLPSAS 2356
T+ P+ +
Sbjct: 1553 TTTLPPTTT 1561
Score = 36.6 bits (83), Expect = 0.36
Identities = 33/136 (24%), Positives = 43/136 (31%), Gaps = 17/136 (12%)
Query: 1044 EKVVVKPEKTEKKDLPPP------PPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQ 1097
+K + P PPP PP P P + PPP PS T
Sbjct: 1393 DKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTT-----PSPPITTTTT 1447
Query: 1098 KPSQDTEKPLEPVSTVQVEPAVKTVNQQTMA-APVVKEEKQPEKVISKDLVIERPRPDSR 1156
P T P P+ST P T + T +P P + P P +
Sbjct: 1448 PPPTTTPSP--PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTT 1505
Query: 1157 PAV---KKESTLPPRT 1169
+ +TLPP T
Sbjct: 1506 TPITPPASTTTLPPTT 1521
Score = 34.7 bits (78), Expect = 1.4
Identities = 51/230 (22%), Positives = 70/230 (30%), Gaps = 26/230 (11%)
Query: 2583 TVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA 2642
T P P + S P +T P P PP+ TT + S P P P
Sbjct: 1430 TTPPPTTTPSPPITTTTTPPPTTTPS---PPISTTTTPPPTTTPSPPTTTPSP-----PT 1481
Query: 2643 GTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRATSTSPNSQSSKM 2702
T TT S P TPP + + PT++P T+T+ +
Sbjct: 1482 TTPSPPTTTTTTPPPTTTP---SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTT 1538
Query: 2703 NSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKAQK 2762
S P T +T P T P + +T S +
Sbjct: 1539 ---------PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589
Query: 2763 VDSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKT 2812
+ ++ PP T PP P P+ P T PI P T
Sbjct: 1590 TITTTTPPPTTTPSPP------TTTTTTPPPTTTPSPPTTTPITPPTSTT 1633
Score = 34.7 bits (78), Expect = 1.4
Identities = 29/119 (24%), Positives = 40/119 (33%), Gaps = 10/119 (8%)
Query: 1059 PPPPPPPQPP--APIQPQSVPPPIQPEAEKFPSTETATL---AQKPSQDTEKPLEPVSTV 1113
PPP P PP PI P + + P P T T T PS T P+ P ++
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553
Query: 1114 QVEPAVKTVN--QQTMAAPVVKEEKQPEKVISKD---LVIERPRPDSRPAVKKESTLPP 1167
P T + T P P + + P P + P+ +T P
Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP 1612
Score = 33.9 bits (76), Expect = 2.3
Identities = 19/69 (27%), Positives = 25/69 (36%), Gaps = 6/69 (8%)
Query: 1059 PPPPPPPQPPAPIQPQ------SVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVST 1112
PPP P PP P + PPP + +T T PS T P+ P ++
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631
Query: 1113 VQVEPAVKT 1121
P T
Sbjct: 1632 TTTLPPTTT 1640
Score = 32.7 bits (73), Expect = 5.2
Identities = 28/122 (22%), Positives = 34/122 (27%), Gaps = 5/122 (4%)
Query: 1053 TEKKDLPP---PPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETAT--LAQKPSQDTEKPL 1107
T LPP P PPP P + P P P T T T PS
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689
Query: 1108 EPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPP 1167
P +T P+ T + + P P +TLPP
Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749
Query: 1168 RT 1169
T
Sbjct: 1750 TT 1751
Score = 32.7 bits (73), Expect = 5.2
Identities = 33/157 (21%), Positives = 56/157 (35%), Gaps = 10/157 (6%)
Query: 2671 PGTPPIAGRST---TPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQPFPTQ 2727
P T PI +T TPT + + +T+P + ++ + Q+ P T T P
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAEL 4209
Query: 2728 FAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKAQKVDSDSSKPPETLTDPPGVCQEKVEE 2787
+ Q+++ S +S + ++ S+ PP T T P
Sbjct: 4210 TTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269
Query: 2788 KPPPA----PSIATKPVRTGPIK---PQAIKTEETKS 2817
PP P T+ TG P ++T T +
Sbjct: 4270 PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 4306
Score = 32.3 bits (72), Expect = 6.8
Identities = 30/115 (26%), Positives = 36/115 (31%), Gaps = 22/115 (19%)
Query: 1059 PPPPPPPQPPA--PIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVE 1116
PPP P PP P P + P P P T T PS T P+ P ++
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT------PSPPTTTPITPPASTTTL 1517
Query: 1117 PAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKES--TLPPRT 1169
P T + T P P + P S TLPP T
Sbjct: 1518 PPTTTPSPPTTTTTTPPPTTTPSP------------PTTTPITPPTSTTTLPPTT 1560
Score = 32.3 bits (72), Expect = 6.8
Identities = 28/116 (24%), Positives = 36/116 (31%), Gaps = 14/116 (12%)
Query: 1059 PPPPPPPQPP--APIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVE 1116
PPP P PP PI P + + P P T T T P P +T
Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT----TPPPTTTPSPPTTTTPSP 1588
Query: 1117 PAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAV---KKESTLPPRT 1169
P + T P P + P P + + +TLPP T
Sbjct: 1589 PTITTTTPPPTTTP-----SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 126 bits (316), Expect = 3e-28
Identities = 142/615 (23%), Positives = 218/615 (35%), Gaps = 66/615 (10%)
Query: 1747 PPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPL 1806
P P P + P +T P P T P + P P + P + P P +P
Sbjct: 264 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 323
Query: 1807 APVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILAS 1866
P + A +T A T+ PA P + PA T A
Sbjct: 324 EPTPTTPKEPAP---TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 380
Query: 1867 ALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPA----PTPVSAP 1922
+ + P P S+P APT SAPT +P + PAP P P +
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440
Query: 1923 NPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGK-SIQTP 1981
PAP P + T K P TT++ K P + + P+ TP T K + TP
Sbjct: 441 KPAPTTPKEPAPTTPK---EPAPTTTK--KPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 495
Query: 1982 QSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQP-PSVSAWNKPLTSFGSAPSSEGAK 2040
+ T E K AP ++L P +P +P P+ P T +AP++ +
Sbjct: 496 EKLAPTTPE----KPAPTT-----PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP-KE 545
Query: 2041 NGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQK 2100
+ E T + AP + P + + K P P ++ P+
Sbjct: 546 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-------- 597
Query: 2101 LPDLSPVENKE------HKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVT 2154
+L+P KE KP P + K ++ P ++P+P T + T P T
Sbjct: 598 --ELAPTTTKEPTSTTCDKPAP----TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651
Query: 2155 TKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTT--PSSSLPNTVATNNTKMEDTL 2212
KE T + E + T T+ P+ + P A K
Sbjct: 652 LKEPAPT--------TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 703
Query: 2213 VNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLT-------FKMESARKAWENSPNVRE 2265
P P T P T + S+ T+ PTT + E KA ENSP +E
Sbjct: 704 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP--KE 761
Query: 2266 KGSPVTSTAPPIATGVSSSASGPST---ANYNSFSSASMPQIPVASVTPTASLSGAGTYT 2322
G P T T ++++A +T ++ + P++ + T T + +
Sbjct: 762 PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 821
Query: 2323 TSSLSTKSTTTSDPP 2337
T++ T +TT P
Sbjct: 822 TTTQVTSTTTQDTTP 836
Score = 116 bits (291), Expect = 3e-25
Identities = 172/713 (24%), Positives = 257/713 (36%), Gaps = 101/713 (14%)
Query: 1702 EEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSAS 1761
+E + V + K + T+K K++ T ++ QS AP +
Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197
Query: 1762 VP-ASTSAPLPATLTPV-PASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASV 1819
P A T+ PA TP P T+ PAST T + ++P P + + + S
Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPK--EPTPTTIKSAPTTPKEPAPTTTKSA 255
Query: 1820 PASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPA 1879
P + A T++ PA P + PA T + S P A T+ PAP
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT---TKSAPTTPKEPAPTTPKKPAPT 312
Query: 1880 AS---SPAAPVITAPTIPAS-APTASVPLAPASASAPAPA----PTPVSAPNPAP----- 1926
+P P PT P APT P AP + PAP P P + PAP
Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEP-APTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 371
Query: 1927 PAPAQTQAQTHKPVQNPLQTTSQS----SKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQ 1982
PAP T+ + + P TT++S +K+P P+ + TP +
Sbjct: 372 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--------------E 417
Query: 1983 SHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQP-PSVSAWNKPLTSFGSAPSSEGAKN 2041
T T E PA KK P +P +P P+ P T+ AP++
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTT--PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP---- 471
Query: 2042 GQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKL 2101
E T + AP + ++ P EK A PE + P ++L
Sbjct: 472 -----KEPAPTTPKETAPTT---PKKLTPTTPEKLAPTTPE---------KPAPTTPEEL 514
Query: 2102 PDLSPVE---NKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKET 2158
+P E +P P + + N + A P ++P+P T + P T KET
Sbjct: 515 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA----PTTPKEPAPTTPKEPAPTTPKET 570
Query: 2159 KAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL 2218
+ T T KE TTP P +A TK + + P
Sbjct: 571 APTTPKGTA------------PTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPA 616
Query: 2219 PNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIA 2278
P T P T + + T+ P T K + E +P +K +P AP
Sbjct: 617 PTT-PKGTAPTTPKEPAPTT-PKEPAPTTPKGTAPTTLKEPAPTTPKKPAP-KELAPTTT 673
Query: 2279 TGVSSSAS---GPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSD 2335
G +S+ S P+T + ++ P P P + TTS +ST TTT +
Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEP-APTTPKKPAPTTPETPPPTTSEVST-PTTTKE 731
Query: 2336 PPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIP 2388
P I K + S P S P + + P V +++ AA P
Sbjct: 732 PTTIHKSPDE-----STPELS----AEPTPKALENSPKEPGVPTTKTPAATKP 775
Score = 114 bits (286), Expect = 1e-24
Identities = 188/909 (20%), Positives = 303/909 (33%), Gaps = 93/909 (10%)
Query: 1414 DPARERPRRQRPTRPPRQDKPPR------FRRLREREAASKSNEVVAVPTNGTVNNVAQE 1467
D + R +++ +PP D+ F+ + ++ N+V P T +
Sbjct: 68 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA-----K 122
Query: 1468 PVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERD--EKKNADLNAQTVV 1525
P+N + N D S + S E E++ N++ D EK + Q++
Sbjct: 123 PINPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 180
Query: 1526 KVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKR 1585
K L P ++ + PK+ GP P + K
Sbjct: 181 KTSAKDLAPTSKVLAKP-----------------TPKAETTTKGPALTTPKEPTPTTPK- 222
Query: 1586 GPFDDQPAGTTGVD----LINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKE 1641
+PA TT + I + +E P T + +P P PKE
Sbjct: 223 -----EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277
Query: 1642 KVDALSQFDL-NNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRK 1700
++ S P T + P + + K+ +E
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPTPTTPKEPAP 335
Query: 1701 KEEQVIQVWNKK---NANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPS 1757
++ K+ A +K T K P K+ + S + P + P+
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA----PT 391
Query: 1758 TSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSA 1817
T+ S P +T P P T P + P P +T P + P P +P P + A
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451
Query: 1818 SVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPA 1877
A T AP + P P + P + L + LA APT
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-T 510
Query: 1878 PAASSPAAPVITAPTIPAS-APTASVPLAPASASAPAPA----PTPVSAPNPAPPAPAQT 1932
P +P P PT P APT AP + PAP P P + PAP P +T
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570
Query: 1933 QAQTHK-----PVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTL 1987
T K ++ P TT K+P P P+ T T + TP+
Sbjct: 571 APTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTT-TKEPTSTTCDKPAPTTPKGTAPT 626
Query: 1988 T----AELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQ 2043
T A + AP L +P P + T+ S+ K
Sbjct: 627 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686
Query: 2044 ESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQ-----KQPRAGPIKA 2098
+ E T + AP + P + ++ P ++ K P +
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Query: 2099 QKLPDLSPVENKEHKPG-PIGK-ERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTK 2156
P +EN +PG P K + K A+ E + +P T + P TK
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA-PKMTK 805
Query: 2157 ETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDY---TTPSSSLPNTVATNNTKMEDTLV 2213
ET +E +TE + I+ ++ + + + T + T +++L V T + T +
Sbjct: 806 ETATTTEKTTE--SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 863
Query: 2214 NNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVRE-KGSP--- 2269
N P P ++ S + T P K S +K + P VR+ K +P
Sbjct: 864 MNKPEETAKP---KDRATNSKATTPKPQKPTKAPKKPTSTKKP-KTMPRVRKPKTTPTPR 919
Query: 2270 -VTSTAPPI 2277
+TST P +
Sbjct: 920 KMTSTMPEL 928
Score = 56.2 bits (134), Expect = 4e-07
Identities = 107/526 (20%), Positives = 170/526 (32%), Gaps = 64/526 (12%)
Query: 1874 PTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQ 1933
PTP P A + + P S +++P P P+ P + T
Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137
Query: 1934 AQTHKPVQNPL--------------------QTTS---------QSSKQPPPSIRLPSAQ 1964
+T V +TTS S+K P+ ++ +
Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197
Query: 1965 TPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWN 2024
TP + G ++ TP+ T + + P + K P +P +P + +
Sbjct: 198 TPK-AETTTKGPALTTPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 2025 KPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGN----ENEVVPVLSEKSADKI 2080
P T AP++ + + E T + AP + + E P +K A
Sbjct: 255 APTTPKEPAPTTT-KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313
Query: 2081 P-EPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQ 2139
P EP K+P K P +P P ++ + A P
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA----PTTP 369
Query: 2140 EKPSPATVRSTDPVTTKETKAVSEMSTEIGTM--ISVSSAEYGTNAKE-SVTDYTTPSSS 2196
++P+P T + P T KE + S T ++ T KE S T P+ +
Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429
Query: 2197 LPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLT------SVPPTTFSLTFKM 2250
P A K P P T P T ++ + T + P T T K
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 489
Query: 2251 ESARKAWENSPNVREKGSPVT-----STAPPIATGVSSSASGPST-----ANYNSFSSAS 2300
+ + +P EK +P T T P T + P+T N + +
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 2301 MPQIPVASVTP--TASLSGAGTYTTSSLSTKSTTTSDPPNICKVKP 2344
P+ P A TP A + T T+ T TT +P KP
Sbjct: 550 TPKEP-APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594
Score = 52.8 bits (125), Expect = 5e-06
Identities = 74/338 (21%), Positives = 118/338 (34%), Gaps = 33/338 (9%)
Query: 848 SVEHNQLEAHPKADFIRE---------SSEAQVQKFLSRSVED-VRPHHTDANNQSACFE 897
+ +HN++ PK + +S+ + L+ + E V T N+ +
Sbjct: 106 TTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD 165
Query: 898 APDQKTLSAPQE---ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCI 954
+ KT SA + E+ SA + P+ K + T K + P+ PK +
Sbjct: 166 GKE-KTTSAKETQSIEKTSAKDLAPTSKVL----AKPTPKAETTTKGPALTTPKEPTPTT 220
Query: 955 DSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSG 1014
KEP ++P + PK +KS P+ +E +
Sbjct: 221 P-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 279
Query: 1015 PI--KKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQ 1072
P K+P K KE +K +P T K+ P P P+ PAP
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PTPTTPKEPAPTT 337
Query: 1073 PQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQ----QTMA 1128
+ P + A P T ++P+ T P EP T EP+ T + T +
Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT--PKEPAPTTTKEPSPTTPKEPAPTTTKS 395
Query: 1129 APVVKEEKQPEKVISKDLVIERPRP----DSRPAVKKE 1162
AP +E P S + P P + P KE
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433
Score = 52.8 bits (125), Expect = 5e-06
Identities = 129/684 (18%), Positives = 222/684 (32%), Gaps = 61/684 (8%)
Query: 530 EREKDRERQQEKEKELEKEQ----EKQREMEKERKQEKEKELER-QKEKEKELQKM-KEQ 583
+ K+ KE +E ++ KQ + + K KE + +K K+L K
Sbjct: 135 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 194
Query: 584 EKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPV 643
K + K P+EP P K E ++ KE P T + + + KE P
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPT--PTTPK-EPASTTPKEPTPT-TIKSAPTTPKEPAPT 250
Query: 644 VHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQ 703
++ P + +P P K P ++ + ++ T P +
Sbjct: 251 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKK 308
Query: 704 PSSST----VPPPPHRPL-YQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIP 758
P+ +T P P P P +P P P+ + P + +
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 759 PIHPGMIPPKPLMRRDQMEGSPNSSESF-----EHIARSARDHAISLSEPRMLWGSDPYP 813
P P K E +P +++S E + + + EP +P P
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 814 HAEPQQA-TTPK--ATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQ 870
+ A TTPK A P++ + T E P +E++
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAPTT 486
Query: 871 VQKFLSRSVEDVRPHHTDANNQSACFE----APDQKTLSAPQEERISAVESQPSRKRSVS 926
+K + E + P + + E P++ T + P+E + ++
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546
Query: 927 HGSNHTQKPDEQRSEPSAGIPKVTSRCIDS-------KEPIERPEEKPK---------KE 970
+ + EP+ PK T+ KEP +KP KE
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 606
Query: 971 GFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQ 1030
+ + P P + T P P++ + +K+P K+
Sbjct: 607 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP- 665
Query: 1031 RKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPP------PQPPAPIQPQSVPPPIQPEA 1084
KE + T KP T K+ P P P+ PAP P++ PP +
Sbjct: 666 -KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 1085 EKFPSTETATLAQKPSQDT-EKPLEP----VSTVQVEPAVKTVNQQTMAAPVVKEEKQPE 1139
+ E T+ + P + T E EP + EP V T P + + +
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK-D 783
Query: 1140 KVISKDLVIERPRPDSRPAVKKES 1163
K +DL + P + KE+
Sbjct: 784 KTTERDLRTTPETTTAAPKMTKET 807
Score = 47.0 bits (110), Expect = 3e-04
Identities = 119/632 (18%), Positives = 205/632 (32%), Gaps = 87/632 (13%)
Query: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEK----IEPREPNLEPMVEKQESEN 618
KE +E ++ Q + +++ KE + +E+ + P L K E+
Sbjct: 146 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT 205
Query: 619 -----SCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPP 673
+ KE P ++ ++ + KE TP ++ P + +P P K P
Sbjct: 206 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAP 264
Query: 674 RFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPP--PHRPL-YQPMQPHPQHLAS 730
++ ++ + P T S P++ P P P +P P +P P
Sbjct: 265 TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT---- 320
Query: 731 MGFDPRWLMMQSYMDPRMMSGRPAMDIP-------PIHPGMIPPKPLMRRDQMEGSPNSS 783
P+ + +P + PA P P P PK E +P ++
Sbjct: 321 ---TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377
Query: 784 ESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPK-----ATEEPEDVRSEAAL 838
+ E + ++ A + ++ +P P TTPK T+EP +
Sbjct: 378 K--EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435
Query: 839 DQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEA 898
A + PK E + +K + ++ P +
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPK-----EPAPTTTKKPAPTTPKEPAP----TTPKETAPTT 486
Query: 899 PDQKTLSAPQEERISAVESQ-PSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSK 957
P + T + P++ + E P+ ++ + P EP+ PK +
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE-EPAPTTPKAAA----PN 541
Query: 958 EPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIK 1017
P E PK+ E P P ++ T G P++ +K
Sbjct: 542 TPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTT----------------LK 584
Query: 1018 KPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVP 1077
+P K+ KE ++ T KP T K P P + PAP P+ P
Sbjct: 585 EPAPTTPKKPAP--KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP--KEPAPTTPKE-P 639
Query: 1078 PPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQ 1137
P P+ T TL EP T +PA K + T P +
Sbjct: 640 APTTPKG-----TAPTTLK-----------EPAPTTPKKPAPKELAPTTTKGPTSTTSDK 683
Query: 1138 PEKVISKDLVIERPRPDSRPAVKKESTLPPRT 1169
P K+ P+ + KK + P T
Sbjct: 684 PAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 715
Score = 44.7 bits (104), Expect = 0.001
Identities = 143/852 (16%), Positives = 254/852 (29%), Gaps = 99/852 (11%)
Query: 350 SEDQGSKASENNENKKETDEVSNTKS-----SSQIPAQPSVAKVPYGKGPSFNQERGTSS 404
++ + E + KET + T + +S++ A+P+ KGP+ + +
Sbjct: 159 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 218
Query: 405 HLPPPPKLLAQQHPPP----DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVE 460
P P + P P P P P +K E
Sbjct: 219 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE----------------P 262
Query: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELE 520
+E +E E + K+P+P ++ +E
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 322
Query: 521 KEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKM 580
KE KE KE K+ +K E KE
Sbjct: 323 KEPTPTTPKE-------PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 375
Query: 581 KEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEA 640
+E KE K P EP +S + KE P T++ + + KE
Sbjct: 376 TTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434
Query: 641 TPVV---------HETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ 691
P E P + +P P K P ++ ++
Sbjct: 435 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494
Query: 692 QQGVLPQTVPSQPSSST----VPPPPHRPL-YQPMQPHPQHLASMGFDPRWLMMQSYMDP 746
+ + P T P +P+ +T P P P P +P P P+ + +P
Sbjct: 495 PEKLAP-TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-------TPKAAAPNTPKEP 546
Query: 747 RMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHA------ISL 800
+ + P P PK +P + + E + + A +
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTT 604
Query: 801 SEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKA 860
EP P P + T P +EP + A + PK
Sbjct: 605 KEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 662
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPS 920
+E + + S + + P + P + + P++ + E+ P
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718
Query: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPK 980
VS + T++P P P++ S EP + E KE + +++ P
Sbjct: 719 TTSEVSTPTT-TKEPTTIHKSPDESTPEL------SAEPTPKALENSPKEPGVPTTKTPA 771
Query: 981 PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAE 1040
K P ++ +++ +R +R + + KE ++ K
Sbjct: 772 ATK-----------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 820
Query: 1041 KVTEKVV------VKPEK--TEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTET 1092
T +V P K T K P + + P + K +T +
Sbjct: 821 ATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 880
Query: 1093 ATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAP----VVKEEKQPEKVISKDLVI 1148
KP + T+ P +P ST + + + +T P E P I++ ++
Sbjct: 881 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 940
Query: 1149 ERPRPDSRPAVK 1160
RP+ P K
Sbjct: 941 TTTRPNQTPNSK 952
Score = 43.9 bits (102), Expect = 0.002
Identities = 51/268 (19%), Positives = 91/268 (33%), Gaps = 20/268 (7%)
Query: 901 QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPI 960
+ +L+ +E + E+ + K++ + G T E +S I K +++ + P
Sbjct: 139 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS-----IEKTSAKDL---APT 190
Query: 961 ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV 1020
+ KP PK E K + T + +E + P + K
Sbjct: 191 SKVLAKPT----------PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240
Query: 1021 LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPI 1080
KE + ++ +P T K+ P P + PAP +S P
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTP 298
Query: 1081 QPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEK 1140
+ A P T ++P+ T K P + + P K T P K+P
Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 1141 VISKDLVIERPRPDSRPAVKKESTLPPR 1168
K+ P+ + K+ S P+
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 126 bits (316), Expect = 3e-28
Identities = 142/615 (23%), Positives = 218/615 (35%), Gaps = 66/615 (10%)
Query: 1747 PPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPL 1806
P P P + P +T P P T P + P P + P + P P +P
Sbjct: 305 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 364
Query: 1807 APVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILAS 1866
P + A +T A T+ PA P + PA T A
Sbjct: 365 EPTPTTPKEPAP---TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 421
Query: 1867 ALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPA----PTPVSAP 1922
+ + P P S+P APT SAPT +P + PAP P P +
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481
Query: 1923 NPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGK-SIQTP 1981
PAP P + T K P TT++ K P + + P+ TP T K + TP
Sbjct: 482 KPAPTTPKEPAPTTPK---EPAPTTTK--KPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 536
Query: 1982 QSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQP-PSVSAWNKPLTSFGSAPSSEGAK 2040
+ T E K AP ++L P +P +P P+ P T +AP++ +
Sbjct: 537 EKLAPTTPE----KPAPTT-----PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP-KE 586
Query: 2041 NGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQK 2100
+ E T + AP + P + + K P P ++ P+
Sbjct: 587 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-------- 638
Query: 2101 LPDLSPVENKE------HKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVT 2154
+L+P KE KP P + K ++ P ++P+P T + T P T
Sbjct: 639 --ELAPTTTKEPTSTTCDKPAP----TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692
Query: 2155 TKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTT--PSSSLPNTVATNNTKMEDTL 2212
KE T + E + T T+ P+ + P A K
Sbjct: 693 LKEPAPT--------TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 744
Query: 2213 VNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLT-------FKMESARKAWENSPNVRE 2265
P P T P T + S+ T+ PTT + E KA ENSP +E
Sbjct: 745 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP--KE 802
Query: 2266 KGSPVTSTAPPIATGVSSSASGPST---ANYNSFSSASMPQIPVASVTPTASLSGAGTYT 2322
G P T T ++++A +T ++ + P++ + T T + +
Sbjct: 803 PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 862
Query: 2323 TSSLSTKSTTTSDPP 2337
T++ T +TT P
Sbjct: 863 TTTQVTSTTTQDTTP 877
Score = 116 bits (291), Expect = 3e-25
Identities = 172/713 (24%), Positives = 257/713 (36%), Gaps = 101/713 (14%)
Query: 1702 EEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSAS 1761
+E + V + K + T+K K++ T ++ QS AP +
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238
Query: 1762 VP-ASTSAPLPATLTPV-PASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASV 1819
P A T+ PA TP P T+ PAST T + ++P P + + + S
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPK--EPTPTTIKSAPTTPKEPAPTTTKSA 296
Query: 1820 PASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPA 1879
P + A T++ PA P + PA T + S P A T+ PAP
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT---TKSAPTTPKEPAPTTPKKPAPT 353
Query: 1880 AS---SPAAPVITAPTIPAS-APTASVPLAPASASAPAPA----PTPVSAPNPAP----- 1926
+P P PT P APT P AP + PAP P P + PAP
Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEP-APTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 412
Query: 1927 PAPAQTQAQTHKPVQNPLQTTSQS----SKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQ 1982
PAP T+ + + P TT++S +K+P P+ + TP +
Sbjct: 413 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--------------E 458
Query: 1983 SHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQP-PSVSAWNKPLTSFGSAPSSEGAKN 2041
T T E PA KK P +P +P P+ P T+ AP++
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTT--PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP---- 512
Query: 2042 GQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKL 2101
E T + AP + ++ P EK A PE + P ++L
Sbjct: 513 -----KEPAPTTPKETAPTT---PKKLTPTTPEKLAPTTPE---------KPAPTTPEEL 555
Query: 2102 PDLSPVE---NKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKET 2158
+P E +P P + + N + A P ++P+P T + P T KET
Sbjct: 556 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA----PTTPKEPAPTTPKEPAPTTPKET 611
Query: 2159 KAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL 2218
+ T T KE TTP P +A TK + + P
Sbjct: 612 APTTPKGTA------------PTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPA 657
Query: 2219 PNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIA 2278
P T P T + + T+ P T K + E +P +K +P AP
Sbjct: 658 PTT-PKGTAPTTPKEPAPTT-PKEPAPTTPKGTAPTTLKEPAPTTPKKPAP-KELAPTTT 714
Query: 2279 TGVSSSAS---GPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSD 2335
G +S+ S P+T + ++ P P P + TTS +ST TTT +
Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEP-APTTPKKPAPTTPETPPPTTSEVST-PTTTKE 772
Query: 2336 PPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIP 2388
P I K + S P S P + + P V +++ AA P
Sbjct: 773 PTTIHKSPDE-----STPELS----AEPTPKALENSPKEPGVPTTKTPAATKP 816
Score = 114 bits (286), Expect = 1e-24
Identities = 188/909 (20%), Positives = 303/909 (33%), Gaps = 93/909 (10%)
Query: 1414 DPARERPRRQRPTRPPRQDKPPR------FRRLREREAASKSNEVVAVPTNGTVNNVAQE 1467
D + R +++ +PP D+ F+ + ++ N+V P T +
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA-----K 163
Query: 1468 PVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERD--EKKNADLNAQTVV 1525
P+N + N D S + S E E++ N++ D EK + Q++
Sbjct: 164 PINPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 221
Query: 1526 KVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKR 1585
K L P ++ + PK+ GP P + K
Sbjct: 222 KTSAKDLAPTSKVLAKP-----------------TPKAETTTKGPALTTPKEPTPTTPK- 263
Query: 1586 GPFDDQPAGTTGVD----LINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKE 1641
+PA TT + I + +E P T + +P P PKE
Sbjct: 264 -----EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318
Query: 1642 KVDALSQFDL-NNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRK 1700
++ S P T + P + + K+ +E
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPTPTTPKEPAP 376
Query: 1701 KEEQVIQVWNKK---NANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPS 1757
++ K+ A +K T K P K+ + S + P + P+
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA----PT 432
Query: 1758 TSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSA 1817
T+ S P +T P P T P + P P +T P + P P +P P + A
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492
Query: 1818 SVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPA 1877
A T AP + P P + P + L + LA APT
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-T 551
Query: 1878 PAASSPAAPVITAPTIPAS-APTASVPLAPASASAPAPA----PTPVSAPNPAPPAPAQT 1932
P +P P PT P APT AP + PAP P P + PAP P +T
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611
Query: 1933 QAQTHK-----PVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTL 1987
T K ++ P TT K+P P P+ T T + TP+
Sbjct: 612 APTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTT-TKEPTSTTCDKPAPTTPKGTAPT 667
Query: 1988 T----AELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQ 2043
T A + AP L +P P + T+ S+ K
Sbjct: 668 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727
Query: 2044 ESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQ-----KQPRAGPIKA 2098
+ E T + AP + P + ++ P ++ K P +
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Query: 2099 QKLPDLSPVENKEHKPG-PIGK-ERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTK 2156
P +EN +PG P K + K A+ E + +P T + P TK
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA-PKMTK 846
Query: 2157 ETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDY---TTPSSSLPNTVATNNTKMEDTLV 2213
ET +E +TE + I+ ++ + + + T + T +++L V T + T +
Sbjct: 847 ETATTTEKTTE--SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 904
Query: 2214 NNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVRE-KGSP--- 2269
N P P ++ S + T P K S +K + P VR+ K +P
Sbjct: 905 MNKPEETAKP---KDRATNSKATTPKPQKPTKAPKKPTSTKKP-KTMPRVRKPKTTPTPR 960
Query: 2270 -VTSTAPPI 2277
+TST P +
Sbjct: 961 KMTSTMPEL 969
Score = 56.2 bits (134), Expect = 4e-07
Identities = 107/526 (20%), Positives = 170/526 (32%), Gaps = 64/526 (12%)
Query: 1874 PTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQ 1933
PTP P A + + P S +++P P P+ P + T
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178
Query: 1934 AQTHKPVQNPL--------------------QTTS---------QSSKQPPPSIRLPSAQ 1964
+T V +TTS S+K P+ ++ +
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238
Query: 1965 TPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWN 2024
TP + G ++ TP+ T + + P + K P +P +P + +
Sbjct: 239 TPK-AETTTKGPALTTPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 2025 KPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGN----ENEVVPVLSEKSADKI 2080
P T AP++ + + E T + AP + + E P +K A
Sbjct: 296 APTTPKEPAPTTT-KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354
Query: 2081 P-EPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQ 2139
P EP K+P K P +P P ++ + A P
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA----PTTP 410
Query: 2140 EKPSPATVRSTDPVTTKETKAVSEMSTEIGTM--ISVSSAEYGTNAKE-SVTDYTTPSSS 2196
++P+P T + P T KE + S T ++ T KE S T P+ +
Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470
Query: 2197 LPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLT------SVPPTTFSLTFKM 2250
P A K P P T P T ++ + T + P T T K
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 530
Query: 2251 ESARKAWENSPNVREKGSPVT-----STAPPIATGVSSSASGPST-----ANYNSFSSAS 2300
+ + +P EK +P T T P T + P+T N + +
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 2301 MPQIPVASVTP--TASLSGAGTYTTSSLSTKSTTTSDPPNICKVKP 2344
P+ P A TP A + T T+ T TT +P KP
Sbjct: 591 TPKEP-APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635
Score = 52.8 bits (125), Expect = 5e-06
Identities = 74/338 (21%), Positives = 118/338 (34%), Gaps = 33/338 (9%)
Query: 848 SVEHNQLEAHPKADFIRE---------SSEAQVQKFLSRSVED-VRPHHTDANNQSACFE 897
+ +HN++ PK + +S+ + L+ + E V T N+ +
Sbjct: 147 TTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD 206
Query: 898 APDQKTLSAPQE---ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCI 954
+ KT SA + E+ SA + P+ K + T K + P+ PK +
Sbjct: 207 GKE-KTTSAKETQSIEKTSAKDLAPTSKVL----AKPTPKAETTTKGPALTTPKEPTPTT 261
Query: 955 DSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSG 1014
KEP ++P + PK +KS P+ +E +
Sbjct: 262 P-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 320
Query: 1015 PI--KKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQ 1072
P K+P K KE +K +P T K+ P P P+ PAP
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PTPTTPKEPAPTT 378
Query: 1073 PQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQ----QTMA 1128
+ P + A P T ++P+ T P EP T EP+ T + T +
Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT--PKEPAPTTTKEPSPTTPKEPAPTTTKS 436
Query: 1129 APVVKEEKQPEKVISKDLVIERPRP----DSRPAVKKE 1162
AP +E P S + P P + P KE
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474
Score = 52.8 bits (125), Expect = 5e-06
Identities = 129/684 (18%), Positives = 222/684 (32%), Gaps = 61/684 (8%)
Query: 530 EREKDRERQQEKEKELEKEQ----EKQREMEKERKQEKEKELER-QKEKEKELQKM-KEQ 583
+ K+ KE +E ++ KQ + + K KE + +K K+L K
Sbjct: 176 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 235
Query: 584 EKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPV 643
K + K P+EP P K E ++ KE P T + + + KE P
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPT--PTTPK-EPASTTPKEPTPT-TIKSAPTTPKEPAPT 291
Query: 644 VHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQ 703
++ P + +P P K P ++ + ++ T P +
Sbjct: 292 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKK 349
Query: 704 PSSST----VPPPPHRPL-YQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIP 758
P+ +T P P P P +P P P+ + P + +
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 759 PIHPGMIPPKPLMRRDQMEGSPNSSESF-----EHIARSARDHAISLSEPRMLWGSDPYP 813
P P K E +P +++S E + + + EP +P P
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 814 HAEPQQA-TTPK--ATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQ 870
+ A TTPK A P++ + T E P +E++
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAPTT 527
Query: 871 VQKFLSRSVEDVRPHHTDANNQSACFE----APDQKTLSAPQEERISAVESQPSRKRSVS 926
+K + E + P + + E P++ T + P+E + ++
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587
Query: 927 HGSNHTQKPDEQRSEPSAGIPKVTSRCIDS-------KEPIERPEEKPK---------KE 970
+ + EP+ PK T+ KEP +KP KE
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 647
Query: 971 GFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQ 1030
+ + P P + T P P++ + +K+P K+
Sbjct: 648 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP- 706
Query: 1031 RKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPP------PQPPAPIQPQSVPPPIQPEA 1084
KE + T KP T K+ P P P+ PAP P++ PP +
Sbjct: 707 -KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 1085 EKFPSTETATLAQKPSQDT-EKPLEP----VSTVQVEPAVKTVNQQTMAAPVVKEEKQPE 1139
+ E T+ + P + T E EP + EP V T P + + +
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK-D 824
Query: 1140 KVISKDLVIERPRPDSRPAVKKES 1163
K +DL + P + KE+
Sbjct: 825 KTTERDLRTTPETTTAAPKMTKET 848
Score = 47.0 bits (110), Expect = 3e-04
Identities = 119/632 (18%), Positives = 205/632 (32%), Gaps = 87/632 (13%)
Query: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEK----IEPREPNLEPMVEKQESEN 618
KE +E ++ Q + +++ KE + +E+ + P L K E+
Sbjct: 187 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT 246
Query: 619 -----SCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPP 673
+ KE P ++ ++ + KE TP ++ P + +P P K P
Sbjct: 247 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAP 305
Query: 674 RFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPP--PHRPL-YQPMQPHPQHLAS 730
++ ++ + P T S P++ P P P +P P +P P
Sbjct: 306 TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT---- 361
Query: 731 MGFDPRWLMMQSYMDPRMMSGRPAMDIP-------PIHPGMIPPKPLMRRDQMEGSPNSS 783
P+ + +P + PA P P P PK E +P ++
Sbjct: 362 ---TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418
Query: 784 ESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPK-----ATEEPEDVRSEAAL 838
+ E + ++ A + ++ +P P TTPK T+EP +
Sbjct: 419 K--EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476
Query: 839 DQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEA 898
A + PK E + +K + ++ P +
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPK-----EPAPTTTKKPAPTTPKEPAP----TTPKETAPTT 527
Query: 899 PDQKTLSAPQEERISAVESQ-PSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSK 957
P + T + P++ + E P+ ++ + P EP+ PK +
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE-EPAPTTPKAAA----PN 582
Query: 958 EPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIK 1017
P E PK+ E P P ++ T G P++ +K
Sbjct: 583 TPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTT----------------LK 625
Query: 1018 KPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVP 1077
+P K+ KE ++ T KP T K P P + PAP P+ P
Sbjct: 626 EPAPTTPKKPAP--KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP--KEPAPTTPKE-P 680
Query: 1078 PPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQ 1137
P P+ T TL EP T +PA K + T P +
Sbjct: 681 APTTPKG-----TAPTTLK-----------EPAPTTPKKPAPKELAPTTTKGPTSTTSDK 724
Query: 1138 PEKVISKDLVIERPRPDSRPAVKKESTLPPRT 1169
P K+ P+ + KK + P T
Sbjct: 725 PAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 756
Score = 44.7 bits (104), Expect = 0.001
Identities = 143/852 (16%), Positives = 254/852 (29%), Gaps = 99/852 (11%)
Query: 350 SEDQGSKASENNENKKETDEVSNTKS-----SSQIPAQPSVAKVPYGKGPSFNQERGTSS 404
++ + E + KET + T + +S++ A+P+ KGP+ + +
Sbjct: 200 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 259
Query: 405 HLPPPPKLLAQQHPPP----DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVE 460
P P + P P P P P +K E
Sbjct: 260 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE----------------P 303
Query: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELE 520
+E +E E + K+P+P ++ +E
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 363
Query: 521 KEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKM 580
KE KE KE K+ +K E KE
Sbjct: 364 KEPTPTTPKE-------PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 416
Query: 581 KEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEA 640
+E KE K P EP +S + KE P T++ + + KE
Sbjct: 417 TTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475
Query: 641 TPVV---------HETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ 691
P E P + +P P K P ++ ++
Sbjct: 476 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535
Query: 692 QQGVLPQTVPSQPSSST----VPPPPHRPL-YQPMQPHPQHLASMGFDPRWLMMQSYMDP 746
+ + P T P +P+ +T P P P P +P P P+ + +P
Sbjct: 536 PEKLAP-TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-------TPKAAAPNTPKEP 587
Query: 747 RMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHA------ISL 800
+ + P P PK +P + + E + + A +
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTT 645
Query: 801 SEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKA 860
EP P P + T P +EP + A + PK
Sbjct: 646 KEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 703
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPS 920
+E + + S + + P + P + + P++ + E+ P
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759
Query: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPK 980
VS + T++P P P++ S EP + E KE + +++ P
Sbjct: 760 TTSEVSTPTT-TKEPTTIHKSPDESTPEL------SAEPTPKALENSPKEPGVPTTKTPA 812
Query: 981 PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAE 1040
K P ++ +++ +R +R + + KE ++ K
Sbjct: 813 ATK-----------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 861
Query: 1041 KVTEKVV------VKPEK--TEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTET 1092
T +V P K T K P + + P + K +T +
Sbjct: 862 ATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 921
Query: 1093 ATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAP----VVKEEKQPEKVISKDLVI 1148
KP + T+ P +P ST + + + +T P E P I++ ++
Sbjct: 922 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 981
Query: 1149 ERPRPDSRPAVK 1160
RP+ P K
Sbjct: 982 TTTRPNQTPNSK 993
Score = 43.9 bits (102), Expect = 0.002
Identities = 51/268 (19%), Positives = 91/268 (33%), Gaps = 20/268 (7%)
Query: 901 QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPI 960
+ +L+ +E + E+ + K++ + G T E +S I K +++ + P
Sbjct: 180 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS-----IEKTSAKDL---APT 231
Query: 961 ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV 1020
+ KP PK E K + T + +E + P + K
Sbjct: 232 SKVLAKPT----------PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281
Query: 1021 LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPI 1080
KE + ++ +P T K+ P P + PAP +S P
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTP 339
Query: 1081 QPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEK 1140
+ A P T ++P+ T K P + + P K T P K+P
Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 1141 VISKDLVIERPRPDSRPAVKKESTLPPR 1168
K+ P+ + K+ S P+
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 125 bits (315), Expect = 5e-28
Identities = 76/267 (28%), Positives = 148/267 (55%), Gaps = 7/267 (2%)
Query: 432 FPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEK 491
F + +E++ K++ RQ+ E ER R+R E ERR E+ + E+ K E+
Sbjct: 284 FRDTHKKLEEEKGKKEKERQEIEKERR-ERERERERERERREREREREREREREKE-KER 341
Query: 492 LGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEK 551
E+ + +ER+R+++RER+++ ++E+ +R K+R + RE+ +++E+E E+E+E+
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER 401
Query: 552 QREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMV 611
+RE E+ER++E+E+E ER++E+E+E K +++E++ E ER KLE K+ +E + +
Sbjct: 402 EREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461
Query: 612 EKQE-SENSCNKEEEPVFTRQDSNRSE--KEATPVVHETEPESGSQPRPAVLSGYFKQFQ 668
+ E E +E E R++ R E KEA + E + P G Q
Sbjct: 462 KNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG--SALQ 519
Query: 669 KSLPPRFQRQQEQMKQQQWQQQQQQGV 695
K L R + + + ++ ++++ + +
Sbjct: 520 KRLRDREKEMEADERDRKREKEELEEI 546
Score = 121 bits (304), Expect = 9e-27
Identities = 81/285 (28%), Positives = 159/285 (55%), Gaps = 29/285 (10%)
Query: 429 PGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRL 488
P P +K+ + + E+ + +R S + K+ EEE+ + E++R+ E+ +R
Sbjct: 255 PYPLITKEDI-NAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERE 313
Query: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKE 548
E+ E++ E RERERE+ERERE+E EKE+E+ERE++R++DR ++++++++ E++
Sbjct: 314 RER----ERE---RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERD 366
Query: 549 QEKQRE------------MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKL 596
+++ RE EK R +E+E+E ER++E+E+E ++ +E+E+E E E+ERE+
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 597 EEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSN---RSEKEATPVVHETEPESGS 653
++K RE + E E+++ E +E+E + + N R K+ E E E
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKL-REKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Query: 654 QPRPAVLSGYFKQFQKSL-----PPRFQRQQEQMKQQQWQQQQQQ 693
+ A + K+F + P++ R K+ + ++++ +
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530
Score = 85.1 bits (209), Expect = 9e-16
Identities = 68/250 (27%), Positives = 126/250 (50%), Gaps = 28/250 (11%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
+++ +D ++ + R + + ER R+R E ER E +R+ + +R EK
Sbjct: 371 RERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKK 430
Query: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKERE-KDRERQQEKEKELEKEQEKQR 553
+++ E+ ER + + + REKE QER K E ++R++ +E EKE E+E+E++R
Sbjct: 431 RDREEDEEDAYERRKLERKLREKE---AAYQERLKNWEIRERKKTREYEKEAEREEERRR 487
Query: 554 EMEKERKQEKE--KELERQKEKEK-----ELQK-MKEQEKECEL-EKEREKLEEKIEP-- 602
EM KE K+ KE ++ + ++ K LQK ++++EKE E E++R++ +E++E
Sbjct: 488 EMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIR 547
Query: 603 ----REPNLEPMVEKQESENSCNKEEEPVFTRQDSN---------RSEKEATPVVHETEP 649
E + +P E Q E + +P ++ + + EK P+ E EP
Sbjct: 548 QRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEP 607
Query: 650 ESGSQPRPAV 659
E +P +
Sbjct: 608 EQKPCLKPTL 617
Score = 72.8 bits (177), Expect = 5e-12
Identities = 59/183 (32%), Positives = 102/183 (55%), Gaps = 13/183 (7%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEK-QP 499
E E Q R + EI ER + R E+E EE+R+ A++ KRL E L + +
Sbjct: 452 EKEAAYQERLKNWEIR---ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD 508
Query: 500 SPEEIREREREKE-REREKELE-KEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEK 557
P+ R +K R+REKE+E E++++REKE ++ ++ E + + E QR ME+
Sbjct: 509 DPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR-MEQ 567
Query: 558 ERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP-REPNLEPMVEKQES 616
E ++ ++ +++++ E E+E E+EK+ + EK E +EE+ EP ++P L+P + S
Sbjct: 568 EAERRRQPQIKQEPESEEE-----EEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISS 622
Query: 617 ENS 619
S
Sbjct: 623 APS 625
Score = 72.4 bits (176), Expect = 6e-12
Identities = 53/210 (25%), Positives = 112/210 (53%), Gaps = 17/210 (8%)
Query: 440 DEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDE----KLGIL 495
DE+ + ++ +R+ I A+E + E ++ + +K K E + +
Sbjct: 192 DEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVA 251
Query: 496 EKQPSP----EEIREREREKERER--EKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549
P P E+I E E+++ +E+ K ++ ++ E EK + KEKE ++ +
Sbjct: 252 PLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGK-----KEKERQEIE 306
Query: 550 EKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEP 609
+++RE E+ER++E+E+ ER++E+E+E ++ KE+E+E E E++R++ K R+ + E
Sbjct: 307 KERRERERERERERERR-EREREREREREREKEKERERERERDRDRDRTKERDRDRDRE- 364
Query: 610 MVEKQESENSCNKEEEPVFTRQDSNRSEKE 639
++ E S ++ ++ +R+ S E+E
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSRDRERE 394
Score = 38.9 bits (89), Expect = 0.073
Identities = 105/533 (19%), Positives = 186/533 (34%), Gaps = 65/533 (12%)
Query: 983 KVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKV 1042
K K S P +N EE D +R + K + + E ++++
Sbjct: 173 KAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSH 232
Query: 1043 TEKVVVKPEKTEKKD--LPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPS 1100
K +K EKK+ P P P P+ + I+ E +K + +
Sbjct: 233 PRK-----KKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDK---RDLISREISKF 284
Query: 1101 QDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVK 1160
+DT K LE E K +Q + + E++ E+ ER R + +
Sbjct: 285 RDTHKKLEE------EKGKKEKERQEIEKERRERERERER--------ERERRERERERE 330
Query: 1161 KESTLPPRTYWKEARERDWFPDQGY-RGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYP 1219
+E + RERD D+ R R R R R S + +R
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERS----SDRNKDRSRSRE 386
Query: 1220 QYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKD 1279
+ RD + E R+RE R + E +R R+R E + D + ++D
Sbjct: 387 KSRDRERERE-------REREREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 1280 SLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEP 1339
+ + KL ER +K K + I R + Y ++ ++ + +
Sbjct: 440 AYERRKL----ERKLREKEAAYQERLK---NWEIRERKKTREYEKEAEREEERRREMAKE 492
Query: 1340 TRRGRGGTFRRGGRDPGGRPS--RPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQF 1397
+R + F D P R S L++ RD + E + + E Q
Sbjct: 493 AKRLK--EFLEDYDDDRDDPKYYRGSALQK-RLRDREKEMEADERDRKREKEELEEIRQR 549
Query: 1398 IPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLRE---REAASKSNEVVA 1454
+ P ++ + ER R+ + + P ++ ++ +E E + E
Sbjct: 550 LLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Query: 1455 VP-TNGTVNNVAQEPVNTLGDISGNKTPD-----------LSNQNSSDQANEE 1495
P T+ ++ P ++ SGN TP+ + ++NS DQ E
Sbjct: 610 KPCLKPTLRPISSAP--SVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPE 660
Score = 38.1 bits (87), Expect = 0.12
Identities = 42/198 (21%), Positives = 73/198 (36%), Gaps = 9/198 (4%)
Query: 859 KADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQ 918
K D E + +SR + R H + E Q+ +E R E +
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEI---EKERRERERERE 317
Query: 919 PSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEG 978
R+R ++ E+ E + R + +R E+ + RSS+
Sbjct: 318 RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDR 377
Query: 979 PKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEK 1038
K + KS R R RE +R R ++ R+ + ERE+ K+K+ ++
Sbjct: 378 NKDRSRSREKSRDRERERERERERERERERERER----EREREREREREREREKDKKRDR 433
Query: 1039 AEKVTEKVVVKPEKTEKK 1056
E E+ + K E+K
Sbjct: 434 EE--DEEDAYERRKLERK 449
Score = 35.4 bits (80), Expect = 0.80
Identities = 41/190 (21%), Positives = 77/190 (40%), Gaps = 15/190 (7%)
Query: 906 APQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEE 965
A +ER+ E + +K + +K E+ E + K R + E + +
Sbjct: 455 AAYQERLKNWEIRERKK------TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD 508
Query: 966 KPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRR-EEVNDRPVRRSGPIKKPVLRDM 1024
PK + R S K + + + E R EE+ R + P L+ M
Sbjct: 509 DPK---YYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRM 565
Query: 1025 KEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEA 1084
++E E+R++ + ++ + E+ K EK EK++ P + P Q + P ++P
Sbjct: 566 EQEAERRRQPQIKQEPESEEEEEEKQEKEEKRE----EPMEEEEEPEQKPCLKPTLRP-I 620
Query: 1085 EKFPSTETAT 1094
PS +A+
Sbjct: 621 SSAPSVSSAS 630
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 123 bits (308), Expect = 3e-27
Identities = 301/1448 (20%), Positives = 484/1448 (33%), Gaps = 184/1448 (12%)
Query: 1425 PTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGD-ISGNKTPDL 1483
PT PR+ +PP + ++P + T VA +NTL ++ +TP
Sbjct: 1917 PTSTPREGRPP----------------LTSIPVSTTT--VASSEINTLSTTLADTRTPVT 1958
Query: 1484 SNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSF 1543
+ +S T+ + ++E + L+ VV ++ S
Sbjct: 1959 TYSQASSSPTTADGTSMPTPAYSEGST--PLTSMPLSTTLVVS------------SEAST 2004
Query: 1544 SSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLING 1603
S PVD + S +G + + S P S + P P TT V G
Sbjct: 2005 LSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP---SERTTPLAGMPVSTTLVVSSEG 2061
Query: 1604 SS-----AHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQF-----DLNN 1653
++ + V N T +S + G P P LS + +
Sbjct: 2062 NTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEAST 2121
Query: 1654 YASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKN 1713
++ + + P +T E S + +G + S +R V
Sbjct: 2122 LSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTL 2181
Query: 1714 ANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPAT 1773
+ + T A+ T + S P S P +++P TS +T
Sbjct: 2182 STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEA--ST 2239
Query: 1774 LTPVPASTSAPVPASTLAPVLASTS--APVPAS-------PLAPVSASASVSASVPASTS 1824
L+ P TS PV ST A +T+ +P S PL + S ++ A+ ST
Sbjct: 2240 LSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL 2299
Query: 1825 AAAITSSSAP----ASAPAPTPILASVSTPASVTILASA-------SIPILASALASTSA 1873
+ S+ P A +P P S P S + + S ++AS ST +
Sbjct: 2300 STTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS 2359
Query: 1874 PTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQ 1933
TPA S+P A + P +A S+P + S + PVS P + A T
Sbjct: 2360 TTPADT-STPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVST-MPVVSSEASTH 2417
Query: 1934 AQTHKPVQNPLQTTSQSSKQPPPS--IRLPSAQTPNGTDYVASGKSIQTP---QSHGTLT 1988
+ T P+ T++++S P + +P++ GT +AS TP GTL+
Sbjct: 2418 STTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLS 2477
Query: 1989 AELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLE 2048
D S P S A + P T+ A G
Sbjct: 2478 TTPVDT------------------STPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTS 2519
Query: 2049 IGTDTIQFGAPASN-------GNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKL 2101
I T +P ++ + + VV S+ E G + +
Sbjct: 2520 IPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSM 2579
Query: 2102 PDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTD-PVTTKETKA 2160
P KP + +L V + V + SP T + T P++T +
Sbjct: 2580 P-------VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVS 2632
Query: 2161 VSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPN 2220
S S + TM SS E+ T TTP + + T T +P
Sbjct: 2633 TSLTSILVSTMPVASS--------EASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPT 2684
Query: 2221 TLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATG 2280
+ P ++S+ LT++ +T L S + S S++P A G
Sbjct: 2685 STP------GERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEG 2738
Query: 2281 VSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNIC 2340
S S PS + +S + +PVAS AS TS T ST S P
Sbjct: 2739 TSMRISTPSDGS-TPLTSILVSTLPVAS--SEASTVSTTAVDTSIPVTTSTEASSSPTTA 2795
Query: 2341 KVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNT 2400
+V T S S + L+ MP P V+ S A + +DTS T
Sbjct: 2796 EVTSMPTSTPSETS----TPLTSMP-----VNHTP---VASSEAGTLSTTPVDTSTPVTT 2843
Query: 2401 QHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPI-YAPLQGQHQAQLSL----GAGPAVSQ 2455
+ P+ A+ + S IP+ P+ + LS + P +
Sbjct: 2844 STKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTS 2903
Query: 2456 AQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSN 2515
+ S + S P S +S P L+ + P S L+
Sbjct: 2904 TEGSSSPTTAEGTSMPISTPSEVSTP---LTSILVSTVPVA-----GSEASTLSTTPVDT 2955
Query: 2516 TQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQ--------ASNLYSGQVQQPGQT 2567
P+ E + G S I T + R LT AS+ S + P T
Sbjct: 2956 RTPVTTSAEASSSPTTAEGTSMPISTP-GERRTPLTSMSVSTMPVASSEASTLSRTPADT 3014
Query: 2568 NFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLS 2627
+ T + ++ T +S P+ GST PL ++P + P P+A S +
Sbjct: 3015 STPVTTSTEASSSPTTAEGTGIPISTPSEGST--PLTSIPVSTTPV---AIPEASTLS-T 3068
Query: 2628 RPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTP-TSS 2686
P + P + T+ S T + + M + + G G P STTP TSS
Sbjct: 3069 TPVDSNSP----VVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPV----STTPVTSS 3120
Query: 2687 PFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFF 2746
ST+P S+ + + + S+P T T PT + + +
Sbjct: 3121 AISTLSTTPVDTSTPVTT---STEAHSSPTTSEGTS-MPTSTPSEGSTPLTYMPVSTMLV 3176
Query: 2747 SEQQQSKQIGGGKAQKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIK 2806
+ S D+S P T T+ + P PS P+ + P+
Sbjct: 3177 VSSEDS------TLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVS 3230
Query: 2807 PQAIKTEE 2814
+ + E
Sbjct: 3231 NTPVASSE 3238
Score = 116 bits (290), Expect = 4e-25
Identities = 242/1144 (21%), Positives = 417/1144 (36%), Gaps = 171/1144 (14%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPA-TLTPVPASTSAPVPASTLAPV 1793
T + + S PL S P+ S AST + P T TPV ST A +T
Sbjct: 2385 TSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGT 2444
Query: 1794 LASTSAP---------VPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPIL 1844
TS P +P S VS+ A ++ P TS TS+ A +S I+
Sbjct: 2445 SIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIV 2504
Query: 1845 ASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPL 1904
+ST + + L + SIP+ + +AS A T + +PV+T+ I +SA +A
Sbjct: 2505 VPISTASEGSTLLT-SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTS 2563
Query: 1905 APASASAPAPAP---TPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPS---- 1957
P S + P PVS P + A T + T P+ T++++S P +
Sbjct: 2564 MPTSTYSEGSTPLRSMPVST-KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTS 2622
Query: 1958 --IRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPP 2015
I PS + + T + S + + ++ TL+ D + S
Sbjct: 2623 MPISTPSEVSTSLTSILVSTMPVASSEA-STLSTTPVDTRTLVTTSTGTSSSPTTAEGSS 2681
Query: 2016 QPPSV-SAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSE 2074
P S + PLT+ S+ N + S L T + P + E P +E
Sbjct: 2682 MPTSTPGERSTPLTNI--LVSTTLLANSEASTL--STTPVDTSTPVTTSAEASSSPTTAE 2737
Query: 2075 KSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQV 2134
++ +I P + + P+ + + L PV + E ++ V + V
Sbjct: 2738 GTSMRISTPSD------GSTPLTSILVSTL-PVASSE--------ASTVSTTAVDTSIPV 2782
Query: 2135 EPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTM----ISVSSAEYGTNAKESVTDY 2190
+ SP T VT+ T SE ST + +M V+S+E GT +
Sbjct: 2783 TTSTEASSSPTTAE----VTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLS------- 2831
Query: 2191 TTP-SSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFK 2249
TTP +S P T +T + T V +P + S+ LTS+P +T +
Sbjct: 2832 TTPVDTSTPVTTSTKASSSPTTAEGIV-------VPISTASEGSTLLTSIPVSTTPVASS 2884
Query: 2250 MESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASV 2309
S ++ S S++P A G S S PS + +S + +PVA
Sbjct: 2885 EASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVS-TPLTSILVSTVPVAG- 2942
Query: 2310 TPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIA 2369
S A T +T+ + T++ T+ + SS P+ ++ + MP
Sbjct: 2943 ------SEASTLSTTPVDTRTPVTT-----------SAEASSSPTT---AEGTSMPISTP 2982
Query: 2370 QQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQI 2429
+++ P +S S +P + S L T P + + + S PT+ +
Sbjct: 2983 GERRTPLTSMSVST---MPVASSEASTLSRTPADTSTPVTTSTEAS-----SSPTTAEGT 3034
Query: 2430 PIPIYAPLQGQHQ-AQLSLGAGP-AVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSG 2487
IPI P +G + + P A+ +A L ++ + + P + +S G
Sbjct: 3035 GIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD--SNSPVVTSTEVSSSPTPAEG 3092
Query: 2488 TAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQAR 2547
T++ P + E + +G+ T T + T +
Sbjct: 3093 TSM---PISTYSEGSTPLTGVPVSTTPVTS----------------SAISTLSTTPVDTS 3133
Query: 2548 ANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLS-LPNFGSTGQPLIAL 2606
+T ++ +S G T+ S + + PL +S + S L A
Sbjct: 3134 TPVTTSTEAHSSPTTSEG------TSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSAT 3187
Query: 2607 PQTLQPPL---QHTTPQAQAQSLSRPAQVSQPFRGLIP-----------AGTQHSMIATT 2652
P P+ T A+ S P S P G+ P A ++ S+++TT
Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIP--TSTPSEGMTPLTSVPVSNTPVASSEASILSTT 3245
Query: 2653 GKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFR----------ATSTSPNSQSSKM 2702
S L +PP A ++ PTS+P +T+T +S++S +
Sbjct: 3246 PVDSNTPLTTSTEA----SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTL 3301
Query: 2703 NS--------IVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQ 2754
++ + Q S+P T + ++ + + ST S + +
Sbjct: 3302 STTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEAST-- 3359
Query: 2755 IGGGKAQKVDSDSSKPPETLTDPP-GVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTE 2813
D+S P T T+ + P +PS T P+ + P+ + +
Sbjct: 3360 -----LSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSS 3414
Query: 2814 ETKS 2817
E +
Sbjct: 3415 EVNT 3418
Score = 113 bits (282), Expect = 3e-24
Identities = 234/1116 (20%), Positives = 392/1116 (35%), Gaps = 164/1116 (14%)
Query: 1740 AQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAST-LAPVLASTS 1798
A S AS L++ P+ ST + A S+ P T S P ST L +L ST
Sbjct: 2705 ANSEAST--LSTTPVDTSTPVTTSAEASSS-PTTAEGTSMRISTPSDGSTPLTSILVST- 2760
Query: 1799 APVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILAS 1858
PV +S + VS +A V S+P +T+S+ +S+P + + ++ S T
Sbjct: 2761 LPVASSEASTVSTTA-VDTSIP-------VTTSTEASSSPTTAEVTSMPTSTPSETSTPL 2812
Query: 1859 ASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTAS---VPLAPASASAPAPA 1915
S+P+ + +AS+ A T + + PV T+ +S TA VP++ AS +
Sbjct: 2813 TSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLT 2872
Query: 1916 PTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDY-VAS 1974
PVS P + A T + T P+ T+++ S P T GT +++
Sbjct: 2873 SIPVST-TPVASSEASTLSTTPVDTSIPVTTSTEGSSSP---------TTAEGTSMPIST 2922
Query: 1975 GKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAP 2034
+ TP LT+ L + + +S P S A + P T+ G++
Sbjct: 2923 PSEVSTP-----LTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSM 2977
Query: 2035 --SSEGAKNGQESGLEIGTDTI-------------QFGAPASNGNENEVVPVLSEKSADK 2079
S+ G + + + + T + P + E P +E +
Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIP 3037
Query: 2080 IPEPKEQRQK----QPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVE 2135
I P E P+ + LS + P E S +
Sbjct: 3038 ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPI 3097
Query: 2136 PEGQEKPSPAT--VRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYG---TNAKESVTDY 2190
E +P T ST PVT+ +S + T ++ S+ + T+ S+
Sbjct: 3098 STYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS 3157
Query: 2191 TTPSSSLPNTVATNNTKM----EDTLVNNVPLPNTLP-----------------LPKRET 2229
T S P T +T + ED+ ++ P+ + P +P
Sbjct: 3158 TPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTP 3217
Query: 2230 IQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPS 2289
+ + LTSVP + + S N S S++PP A G S S PS
Sbjct: 3218 SEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPS 3277
Query: 2290 TANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQT 2349
S + +PV++ T +S TS+LST TS P V +
Sbjct: 3278 E------GSTPLTSMPVSTTTVASS-------ETSTLSTTPADTSTP-----VTTYSQAS 3319
Query: 2350 SSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPS 2409
SS P A S MP+ + P +S S P + S L T P +
Sbjct: 3320 SSPPIADGTS----MPTSTYSEGSTPLTNMSFSTT---PVVSSEASTLSTTPVDTSTPVT 3372
Query: 2410 LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQ-AQLSLGAGPAVSQAQELFS------- 2461
+ + P ++ TS IP +P +G A + + P VS S
Sbjct: 3373 TSTEASLSPTTAEGTS-----IPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSN 3427
Query: 2462 ---------SSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQEL------AKAQS 2506
SS + S+ S+ S LS + P + +
Sbjct: 3428 TLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTST 3487
Query: 2507 GLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQ 2566
+ +N+ P +G G + L + + ++AS L + P
Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLST----TPVD 3543
Query: 2567 TNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTL----------QPPLQH 2616
+N + T+ S ++ T+ + ++S P+ GS+ + L T P +
Sbjct: 3544 SNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDR 3603
Query: 2617 TTP---QAQAQS-----------LSRPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKA 2662
+TP Q+ S +S P++VS P ++P T I+ G S + +
Sbjct: 3604 STPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLT-IMPVSTTSVTISEAGTASTLPVDT 3662
Query: 2663 FGSGI-DIKPGTPPIAGRSTT-PTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRM 2720
I + + P+ TT P +P ++ S + S P+ V
Sbjct: 3663 STPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTS 3722
Query: 2721 TQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIG 2756
T P + +A + L ST S + +G
Sbjct: 3723 T---PVTTSTEAISSSATLDSTTMSVSMPMEISTLG 3755
Score = 111 bits (278), Expect = 9e-24
Identities = 236/1165 (20%), Positives = 417/1165 (35%), Gaps = 147/1165 (12%)
Query: 1742 SSASVPPLASAPLPPSTS--ASVPASTSAPLPATLTPVPASTSAPVP--ASTLAPVLAST 1797
+S V A P+TS S+P ST + LT +P ST+ + ASTL+ T
Sbjct: 1717 NSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDT 1776
Query: 1798 SAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILA 1857
S PV S A S + + S+P ST + +T + S P ++A+ T
Sbjct: 1777 STPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLT---STPVSHTLVANSEASTLSTTPV 1833
Query: 1858 SASIPILASALASTSAPTPAP----AASSPAAPVITAPTIPASAPTASVPLAPASASAPA 1913
++ P++ S S+S PTPA A S+P+ +IP S T + ++ PA
Sbjct: 1834 DSNSPVVTSTAVSSS-PTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPA 1892
Query: 1914 PAPTPV-------SAPNPAPPA--PAQTQAQTHKPVQN-PLQTTS-QSSKQPPPSIRLPS 1962
TPV S+P A + P T + P+ + P+ TT+ SS+ S L
Sbjct: 1893 VTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLAD 1952
Query: 1963 AQTP-------NGTDYVASGKSIQTP-QSHGT--LTAELWDNKVAPPAVLNDISKKLGPI 2012
+TP + + A G S+ TP S G+ LT+ + + + +S
Sbjct: 1953 TRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDT 2012
Query: 2013 SPPQPPSVSAWNKPLTSFGSA--PSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVP 2070
S P S + P T+ G++ S+ + +G+ + T + +S GN P
Sbjct: 2013 STPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLV----VSSEGNTLSTTP 2068
Query: 2071 VLS--------EKSADKIPEPKEQRQKQPRAGPIKAQKLP-DLSPVENKEH---KPGPIG 2118
V S E S+ E P G +P +PV + E P+
Sbjct: 2069 VDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVD 2128
Query: 2119 KERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAE 2178
+ + + EG + P+T+ S+ I T +S + +
Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAIST-LSTTPVD 2187
Query: 2179 YGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRE--TIQQSSSL 2236
T S ++P++S ++ T+ T ++P+ +T+P+ E T+ +
Sbjct: 2188 TSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPV-STMPVVTSEASTLSATPVD 2246
Query: 2237 TSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSF 2296
TS P TT + SP T+ I T S + P T+ S
Sbjct: 2247 TSTPVTT------------------STEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH 2288
Query: 2297 SSASMPQIPVASVTP-------TASLSGAGTYTTSSLSTKSTTTSDPPN-------ICKV 2342
+ + ++ S TP T S + T+ ++ T+TS N +
Sbjct: 2289 TLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTT 2348
Query: 2343 KPQQLQTSSLPS--------ASHFSQLSCMPSLIAQQQQNPQVYVSQSA-AAQIPAFYMD 2393
+TS+L + + +SQ P+ Y S +P M
Sbjct: 2349 MVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMP 2408
Query: 2394 TSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQ-AQLSLGAGPA 2452
+ H+ + S PT+ + IP P +G A + + P
Sbjct: 2409 VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPV 2468
Query: 2453 VSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQ 2512
VS E + S P + S+ + S + + T A S L
Sbjct: 2469 VS--SEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIST------ASEGSTLLTSI 2520
Query: 2513 TSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNT 2572
+T P+ L S ++ + + + A + +++ T+ Y+
Sbjct: 2521 PVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSM---------PTSTYSE 2571
Query: 2573 AQSPSALQQV-TVPLPASQLSLPNFG--STGQPLIALPQTLQPPLQHTTPQAQAQSLSRP 2629
+P V T PL +S+ S + T P+ +T P TT + + +S P
Sbjct: 2572 GSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSP---TTAKDTSMPISTP 2628
Query: 2630 AQVSQPFRGLI----PAGTQHSMIATTGKMSEMELKAFGSGIDIKPGT-------PPIAG 2678
++VS ++ P + + +T + L +G P T G
Sbjct: 2629 SEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPG 2688
Query: 2679 RSTTPTSSPFRATSTSPNSQSSKMNS--------IVYQKQFQSAPATVRMTQPFPTQFAP 2730
+TP ++ +T+ NS++S +++ + + S+P T T + +
Sbjct: 2689 ERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSD 2748
Query: 2731 QAKQRAEVLQSTQRFFSEQQQSKQIGGGKAQKVDSDSSKPPETLTD-PPGVCQEKVEEKP 2789
+ +L ST S + + D+S P T T+ +V P
Sbjct: 2749 GSTPLTSILVSTLPVASSEAST-------VSTTAVDTSIPVTTSTEASSSPTTAEVTSMP 2801
Query: 2790 PPAPSIATKPVRTGPIKPQAIKTEE 2814
PS + P+ + P+ + + E
Sbjct: 2802 TSTPSETSTPLTSMPVNHTPVASSE 2826
Score = 108 bits (271), Expect = 6e-23
Identities = 252/1183 (21%), Positives = 414/1183 (34%), Gaps = 175/1183 (14%)
Query: 1750 ASAPLPPSTSASVPAST----SAPLP--------------ATLTPVPASTSAPVP----A 1787
AS+P P + S+P ST S PL +TL+ PA TS PV A
Sbjct: 1020 ASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQA 1079
Query: 1788 STLAPVLASTSAP-------------VPASPLAPVSASASVSASVPASTSAAAITSSSAP 1834
S+ + TS P VP S VS+ AS ++ P TS TS+ A
Sbjct: 1080 SSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEA- 1138
Query: 1835 ASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIP 1894
+S+P + ++P S AS+P+ + + S+ A T + V T+
Sbjct: 1139 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEAS 1198
Query: 1895 ASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPV--QNPLQTTSQSSK 1952
+ PTA V P S P P A ++ + PV P+ T++++S
Sbjct: 1199 SPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSS 1258
Query: 1953 QPPPS--IRLPSAQTPNGTDYVAS---GKSIQTPQSHGTLTAELWDNKVAPPAVLNDISK 2007
P + LP++ T G+ + S ++ T TL D K P N++S
Sbjct: 1259 SPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTK-GPVVTSNEVSS 1317
Query: 2008 KLGPISPPQPP--SVSAWNKPLTSF-------GSAPSSEGAKNGQESGLEIGTDTIQFGA 2058
P P + S PLTS S+ S + ++ + T T +
Sbjct: 1318 SPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSS 1377
Query: 2059 PAS-------NGNENE-----------VVPVLSEKSADKIPEPKE-----QRQKQPRAGP 2095
P + N N +E PV+S +++ P + + + P
Sbjct: 1378 PTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSP 1437
Query: 2096 IKAQ--KLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPV 2153
A+ +P +P E K LK+ V + E S V S PV
Sbjct: 1438 TTAEGISIPTSTPSEGK----------TPLKSIPVSNTPVANSEASTL-STTPVDSNSPV 1486
Query: 2154 TTKETKAVSEMSTEIGTMISVSSAEYGTNAKESV-TDYTTPSSSLPNTVATNNTKMEDTL 2212
T + S E GT I++S+ G+ A S+ TT +SS N+++T + T
Sbjct: 1487 VTSTAVSSSPTPAE-GTSIAISTPSEGSTALTSIPVSTTTVASSEINSLST-TPAVTSTP 1544
Query: 2213 VNNVPLPNTLPLPKRETIQQSSSLT--SVPPTTFSLTFKMESARKAWENSPNVREKGSPV 2270
V ++ P T Q+S+ + S P T+ ++ + + +A N+ + S
Sbjct: 1545 VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEA--NTLSTTPIDSKT 1602
Query: 2271 TSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKS 2330
TA A+ +++ T + S S + IPV S TP AS + TT S
Sbjct: 1603 QVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPV-STTPVASPEASTLSTTPVDSNSP 1661
Query: 2331 TTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAF 2390
TS P + +S+P++++ + + S+ + V+ SA + +
Sbjct: 1662 VITSTE---VSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTP-----VASSAISTLSTT 1713
Query: 2391 YMDTSHLFNTQ-HARLAP--------PSLAQQQGFQPGLSQPTSVQQI-----------P 2430
+D S T AR +P P+ +G P S P S + P
Sbjct: 1714 PVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATP 1773
Query: 2431 IPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAI 2490
I P+ +A S S S + P S P + + LS T +
Sbjct: 1774 IDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPV 1833
Query: 2491 -HNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARAN 2549
N P V ++ + + + + P ++ L + T + + N
Sbjct: 1834 DSNSPVVTSTAVSSSPTPAEGTSIATSTPSE--------GSTALTSIPVSTTTVASSETN 1885
Query: 2550 LTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQT 2609
+ V T + + SP+ ++P + P PL ++P
Sbjct: 1886 TLST----TPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP-------PLTSIPV- 1933
Query: 2610 LQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDI 2669
+T + ++ + R + +Q S TT + M A+ G
Sbjct: 1934 -------STTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTP 1986
Query: 2670 KPGTP---------PIAGRSTTP--TSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATV 2718
P + STTP TS+P TST +S + Q S T
Sbjct: 1987 LTSMPLSTTLVVSSEASTLSTTPVDTSTP-ATTSTEGSSSPTTAGGTSIQTSTPSERTTP 2045
Query: 2719 RMTQPFPTQFAPQAK----QRAEVLQSTQRFFSEQQQSKQIGGGKAQKVDSDSSKPPETL 2774
P T ++ V TQ S + S G + + + S P L
Sbjct: 2046 LAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSP-LL 2104
Query: 2775 TDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTEETKS 2817
T P P A +++T PV + P TE + S
Sbjct: 2105 TSIP---LSTTPVASPEASTLSTTPVDSN--SPVITSTEVSSS 2142
Score = 107 bits (268), Expect = 1e-22
Identities = 239/1064 (22%), Positives = 389/1064 (36%), Gaps = 165/1064 (15%)
Query: 1730 AKKQATGIQQAQSSASVPPLASAPLP--PSTSASVPASTSAPLPATLTPVPAST------ 1781
A T + S P S PL P ++ V +S + L AT PV ST
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSAT--PVDTSTPVTTST 3199
Query: 1782 ---------SAPVPASTLAPVLAS-TSAPVPASPLA----------PVSASASVSASVPA 1821
+P ST + + TS PV +P+A PV ++ ++ S A
Sbjct: 3200 EATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEA 3259
Query: 1822 STSAAAITSSSAPASAPA--PTPILASVSTPASVTILASASIPILASALASTSAPTPAPA 1879
S+S +S P S P+ TP+ S P S T +AS+ L++ A TS P +
Sbjct: 3260 SSSPPTAEGTSMPTSTPSEGSTPL---TSMPVSTTTVASSETSTLSTTPADTSTPVTTYS 3316
Query: 1880 ASSPAAPVITAPTIPASA-PTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHK 1938
+S + P+ ++P S S PL S S P + A T + T
Sbjct: 3317 QASSSPPIADGTSMPTSTYSEGSTPLTNMSFST-----------TPVVSSEASTLSTTPV 3365
Query: 1939 PVQNPLQTTSQSSKQPPPS--IRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKV 1996
P+ T++++S P + +P++ GT +AS TP +++E+
Sbjct: 3366 DTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTP----VVSSEVNTLST 3421
Query: 1997 APPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSS----EGAKNGQESGLEIGTD 2052
P ++ S P ++ TS GS P S + T
Sbjct: 3422 TPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTT 3481
Query: 2053 TIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLP-DLSPVENKE 2111
+ P + + P +E ++ E G +P +PV + E
Sbjct: 3482 PVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE--------GSTPLTNMPVSTTPVASSE 3533
Query: 2112 HKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTM 2171
+L V V Q SPAT++ VTT SE S+ + TM
Sbjct: 3534 --------ASTLSTTPVDSNTFVTSSSQASSSPATLQ----VTTMRMSTPSEGSSSLTTM 3581
Query: 2172 ISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETI 2230
+ S+ Y T+++ S + S P T +T + N+ P P + LP
Sbjct: 3582 L--LSSTYVTSSEASTPSTPSVDRSTPVTTSTQS--------NSTPTPPEVITLPMSTPS 3631
Query: 2231 QQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPI-ATGVSSSASGPS 2289
+ S+ LT +P +T S+T PV ++ P I +T VSSS P
Sbjct: 3632 EVSTPLTIMPVSTTSVTISEAGTAST-----------LPVDTSTPVITSTQVSSSPVTP- 3679
Query: 2290 TANYNSFSSASMP-QIPVASVTPTASLSGAGTYTTSS----LSTKSTTTSDPPNIC--KV 2342
+MP P TP ++ + T TSS LST S TS P +
Sbjct: 3680 -------EGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAI 3732
Query: 2343 KPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQH 2402
S+ S S ++S + + I P +S+ IP+ Y TS T
Sbjct: 3733 SSSATLDSTTMSVSMPMEISTLGTTIL-VSTTPVTRFPESSTPSIPSVY--TSMSMTTAS 3789
Query: 2403 ARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSS 2462
+ P+ + P + + + +P+ ++ S + P + L +S
Sbjct: 3790 EGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTS 3849
Query: 2463 SLQPYRSQPA-------FMQSSLSQP--SVVLSGTAIHNFPTVQHQELAKAQSGLAF--- 2510
+ S PA + S S P ++++S T +FP + F
Sbjct: 3850 TKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPS 3909
Query: 2511 QQTSNTQPIPI---LYEHQLGQASGLGGSQLI-DTHLLQARANLTQASNLYSGQVQQPGQ 2566
T++T IP+ + + + S G + I T + + A++ A+ +G V P
Sbjct: 3910 TDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPAT---TGAVSTPVI 3966
Query: 2567 TNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSL 2626
T+ S S+ T + + P +T PL + + P TT + S
Sbjct: 3967 TSTELNTPSTSSSSTTTSFSTTKEFTTPAM-TTAAPLTYVTMSTAPSTPRTTSRGCTTSA 4025
Query: 2627 SRPAQVSQPFRGLIPAGTQHSMIATTGK----MSEMELKAFGSGIDIKPGTPPIAGRSTT 2682
S + S P H+ + T + SE + + I P PP A ST
Sbjct: 4026 STLSATSTP----------HTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPP-AHSSTP 4074
Query: 2683 PTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQPFPT 2726
PT+S A+ST+ N ++ V ++ P+T T FPT
Sbjct: 4075 PTTS---ASSTTVNPEA------VTTMTTRTKPST--RTTSFPT 4107
Score = 104 bits (260), Expect = 1e-21
Identities = 254/1183 (21%), Positives = 410/1183 (34%), Gaps = 170/1183 (14%)
Query: 1712 KNANEKGRSQTSKLPP---RFAKKQATGIQQAQSSASVPPLASAPLP--------PSTSA 1760
K+ N +G + + +P + A +A + S P SA PS S
Sbjct: 208 KSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSN 267
Query: 1761 SVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVP 1820
S P+ S PL T P+ ASTL+ A+T+ PV S A S + + S+P
Sbjct: 268 SAPSGGSTPL--TRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIP 325
Query: 1821 ASTSAAAITSSSAP-ASAPAPT-PILASVSTPASVTILASASIPILASALASTSAPTPAP 1878
ST T S P S PA T P+ S + S+T + ++++ + ++ +S PT A
Sbjct: 326 TST----YTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTL--VTTSTEPSSLPTTAE 379
Query: 1879 AASSPAAPVITAPTIPASAPTASVPLAPASASA----PAPAPTPVSAPNPAPPAPAQTQA 1934
A S + + T + P +++ +A + AS P + T V+ + A +P T
Sbjct: 380 ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT-TAE 438
Query: 1935 QTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGK---SIQTPQSHGTLTAEL 1991
T P + ++ + P + + S++ N + K + T S TAE+
Sbjct: 439 DTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEV 498
Query: 1992 WDNKVAPPA----VLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGL 2047
+ P+ L +S P++ + ++S ++ + S + + G
Sbjct: 499 NSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGT 558
Query: 2048 EIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPV 2107
I T T G+ V+S +++ P + + + S
Sbjct: 559 SIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSS-----STT 613
Query: 2108 ENKEHKPGPIGKER--SLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMS 2165
P ER ++ + V E S V S PVTT T+A S +
Sbjct: 614 AEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTL-STTPVDSNTPVTT-STEATSSST 671
Query: 2166 TEIGTMISVSSAEYGTN-------------AKESVTDYTTPSSSLPNTVATNNTKMEDTL 2212
T GT + S+ G+ + E+ T TTP + + T
Sbjct: 672 TAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTT 731
Query: 2213 VNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTS 2272
+ +P + P + S+ LTS+P + LT S + S S
Sbjct: 732 ADGASMPTSTP------SEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEAS 785
Query: 2273 TAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTT 2332
+P G S S PS S + IPV S+TP S + TT S T
Sbjct: 786 CSPTTTEGTSMPISTPSE------GSPLLTSIPV-SITPVTSPEASTLSTTPVDSNSPVT 838
Query: 2333 TSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYM 2392
TS P + +S+P++++ + + S+ V+ SA + + +
Sbjct: 839 TSTE---VSSSPTPAEGTSMPTSTYSEGRTPLTSMPVS-----TTLVATSAISTLSTTPV 890
Query: 2393 DTS-HLFNTQHARLAP--------PSLAQQQGFQPGLSQPTSVQQI-----------PIP 2432
DTS + N+ AR +P P+ +G P S P S + P+
Sbjct: 891 DTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVD 950
Query: 2433 IYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAI-H 2491
P+ +A S S S P S P + + LS T +
Sbjct: 951 TSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDS 1010
Query: 2492 NFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLT 2551
N P T + P P + ++ GS T L + + T
Sbjct: 1011 NTPLT--------------TSTEASSPPPTAEGTSMPTSTPSEGS----TPLTRMPVSTT 1052
Query: 2552 Q-ASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTL 2610
AS+ S P T+ T S ++ T + S + GST P T
Sbjct: 1053 MVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGST-------PLTS 1105
Query: 2611 QPPLQHTTPQAQAQSLS-RPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDI 2669
P ++A +LS P S P + T+ + S A G+ I
Sbjct: 1106 VPVSTRLVVSSEASTLSTTPVDTSIP-------------VTTSTEASSSPTTAEGTSIPT 1152
Query: 2670 KP---GTPPIAGRSTTPT---SSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQ- 2722
P GT P+A + T SS ST+P ++ + + S P T +T
Sbjct: 1153 SPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQ---VATSTEASSPPPTAEVTSM 1209
Query: 2723 -------------PFPTQFAPQAKQRAEVLQ------STQRFFSEQQQSKQIGGGKAQKV 2763
P + P A A L ST S + S
Sbjct: 1210 PTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLP 1269
Query: 2764 DSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRT-GPI 2805
S +S+ LT P V V P A ++ T PV T GP+
Sbjct: 1270 TSTTSEGSTLLTSIP-VSTTLVTS--PEASTLLTTPVDTKGPV 1309
Score = 103 bits (256), Expect = 3e-21
Identities = 223/1030 (21%), Positives = 381/1030 (36%), Gaps = 137/1030 (13%)
Query: 1718 GRSQTSKLPPRFAKKQATGIQQAQSSASV----PPLASAPLPPSTSASVPASTSAPLPAT 1773
G + T+ + PR +T + +SV P ++S + P+ S + STS
Sbjct: 70 GTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLF 129
Query: 1774 LTPVPASTSAPVPASTLAPV-------LASTSAPVPASPLAPVSASASVSASVPASTSAA 1826
+ ++S P T P+ ++ST A V +PL A S++ V ST
Sbjct: 130 PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLT 189
Query: 1827 AITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAP 1886
T +S+ + P T I S ++ S + S+P +AS+ A T + P
Sbjct: 190 TSTQASSSPTTPESTTIPKSTNSEGSTPL---TSMPASTMKVASSEAITLLTTPVEISTP 246
Query: 1887 VITAPTIPASAPTASVPLAPASASAPAPAPTPVS----APNPAPPAPAQTQAQTHKPVQN 1942
V + +S TA P S SAP+ TP++ + + A T + T
Sbjct: 247 VTISAQASSSPTTAEGP--SLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNI 304
Query: 1943 PLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQS-HGTLTAELWDNKVAPPAV 2001
P+ T++++S P + P T S TP S T+E+ + P
Sbjct: 305 PVITSTEASSSPTTA---EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDT 361
Query: 2002 LNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSE-------GAKNGQESGLEIGTDTI 2054
++ P S P ++ S GS P + A + + I D+
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSK 421
Query: 2055 QFGAPASNGNENEVVPVLSEKSADKIPEPKE----QRQKQPRAGPIKAQKLPDLS--PVE 2108
F AS + + P +E ++ P E P+ + + +LS PV+
Sbjct: 422 TFVTTASEASSS---PTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVD 478
Query: 2109 NKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEI 2168
+K S +V P P + ST PV + E +S +
Sbjct: 479 SKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDT 538
Query: 2169 GTMISVSSAEYGTNAKESVTDYTTP-SSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKR 2227
T ++ SS E+ + TTP +S+P + + + PL N +P+ R
Sbjct: 539 STPVTTSS--------EASSSSTTPEGTSIPTSTPSE---------GSTPLTN-MPVSTR 580
Query: 2228 ETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASG 2287
+ +S TS P S TF S+ + +S E S TST T ++S +
Sbjct: 581 LVVSSEASTTSTTPAD-SNTFVTTSSEAS--SSSTTAEGTSMPTSTYSERGTTITSMS-- 635
Query: 2288 PSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQL 2347
ST S ++++ PV S TP TTS+ +T S+TT+
Sbjct: 636 VSTTLVASSEASTLSTTPVDSNTPV---------TTSTEATSSSTTA------------- 673
Query: 2348 QTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAP 2407
+ +S+P++++ + + S+ V+ S A+ + +DTS T +
Sbjct: 674 EGTSMPTSTYTEGSTPLTSMPVN-----TTLVASSEASTLSTTPVDTSTPVTTSTEASSS 728
Query: 2408 PSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFS--SSLQ 2465
P+ A S +P+ L +A +L P + S +S
Sbjct: 729 PTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEAS-TLSTTPLDTSTHITTSTEASCS 787
Query: 2466 PYRSQPAFMQ-SSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYE 2524
P ++ M S+ S+ S +L+ + P + S L+ + P+ E
Sbjct: 788 PTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPE-----ASTLSTTPVDSNSPVTTSTE 842
Query: 2525 HQLGQASGLGGSQLIDTHLLQARANLTQ--------ASNLYSGQVQQPGQTNFYNTAQSP 2576
G S T+ + R LT A++ S P T+ T +
Sbjct: 843 VSSSPTPAEGTSMPTSTY-SEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE 901
Query: 2577 SALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLS-RPAQVSQP 2635
+ T + S P GST PL ++P + P + ++A++LS P S P
Sbjct: 902 ARSSPTTSEGTSMPTSTPGEGST--PLTSMPDSTTPVV-----SSEARTLSATPVDTSTP 954
Query: 2636 FRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTP-TSSPFRATSTS 2694
+ T+ + TT + G I TP TTP TS+P T +
Sbjct: 955 ----VTTSTEATSSPTTAE-----------GTSIPTSTP---SEGTTPLTSTPVSHTLVA 996
Query: 2695 PNSQSSKMNS 2704
NS++S +++
Sbjct: 997 -NSEASTLST 1005
Score = 94.0 bits (232), Expect = 2e-18
Identities = 186/790 (23%), Positives = 293/790 (37%), Gaps = 153/790 (19%)
Query: 1720 SQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPA-TLTPVP 1778
++ S PP + T + + S PL S P+ +T AS ST + PA T TPV
Sbjct: 3257 TEASSSPPT---AEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVT 3313
Query: 1779 ----ASTSAPVPASTLAPVLASTSAPVPASPLA-----PVSASASVSASVPASTSAAAIT 1829
AS+S P+ T P + P + ++ VS+ AS ++ P TS +T
Sbjct: 3314 TYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTP-VT 3372
Query: 1830 SSSA-------------PASAPA--PTPILASVSTPASVTILASASI------PILASAL 1868
+S+ P S+P+ TP+ S P S T + S+ + P+ ++ L
Sbjct: 3373 TSTEASLSPTTAEGTSIPTSSPSEGTTPL---ASMPVSTTPVVSSEVNTLSTTPVDSNTL 3429
Query: 1869 AST-----SAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASAS----APAPAPTPV 1919
+T S+PT A S P + T + P ++ P+A + AS P TPV
Sbjct: 3430 VTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPV 3489
Query: 1920 SAPNPAPPA---------PAQTQAQTHKPVQN-PLQTTSQSSKQPPPSIRLPSAQTPNGT 1969
+ +P + P T + P+ N P+ TT +S + + L + + T
Sbjct: 3490 TTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSE---ASTLSTTPVDSNT 3546
Query: 1970 DYVASGKSIQTPQSHGTLTAEL----WDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNK 2025
+S ++ +P + T + + +L+ S P PSV
Sbjct: 3547 FVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTP 3606
Query: 2026 PLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPV------LSEK-SAD 2078
TS S N + E+ T+ P+ ++PV +SE +A
Sbjct: 3607 VTTSTQS--------NSTPTPPEV--ITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTAS 3656
Query: 2079 KIPEPKEQ---RQKQPRAGPI--KAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQ 2133
+P Q + P+ + +P +P E L V +
Sbjct: 3657 TLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEG----------STPLTTMPVSTTRV 3706
Query: 2134 VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSS----AEYGTNAKESVTD 2189
EG +P+ V ST PVTT T+A+S +T T +SVS + GT S T
Sbjct: 3707 TSSEGSTLSTPSVVTST-PVTT-STEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTP 3764
Query: 2190 YTT-PSSSLPNTVATNNTKMEDTLVNNVPLPNTL----PLPKRETIQQSSSLTSV----- 2239
T P SS P+ + + T P TL +P T ++S+ LT+V
Sbjct: 3765 VTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPI 3824
Query: 2240 -------------PPTTFSLTFKMESARKAWENSPNV--------REKGSPVT----STA 2274
PP S + ++ V E+ +P+T ST
Sbjct: 3825 SVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTT 3884
Query: 2275 PPIATGVSSSASGP----STANYNSFSSASMPQIPVASV----------TPTASLSGAGT 2320
P + +S AS P ST S +AS P IPVA+ TP ++ T
Sbjct: 3885 LPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPST 3944
Query: 2321 YTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLI--AQQQQNPQVY 2378
TSS + T+ + + +L T S S+S + S A P Y
Sbjct: 3945 PVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTY 4004
Query: 2379 VSQSAAAQIP 2388
V+ S A P
Sbjct: 4005 VTMSTAPSTP 4014
Score = 81.3 bits (199), Expect = 1e-14
Identities = 157/703 (22%), Positives = 263/703 (37%), Gaps = 122/703 (17%)
Query: 1733 QATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAS-TLA 1791
+ T + + +S PL+ PL + AS AST + P T P +TS+P +S T A
Sbjct: 3444 EGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVD-TSTPVTTSSPTNSSPTTA 3502
Query: 1792 PV--LASTSAPVPASPLAPVSASASVSASVPAST-------SAAAITSSSAPASAPAPTP 1842
V + +++A ++PL + S + AS AST S +TSSS +S+PA
Sbjct: 3503 EVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ 3562
Query: 1843 ILAS-VSTPAS-----VTILAS--------ASIPILASALASTSAPTPAPAASSPAAP-V 1887
+ +STP+ T+L S AS P S ST T + S+P P V
Sbjct: 3563 VTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEV 3622
Query: 1888 ITAPT------------IPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQ 1935
IT P +P S + ++ A +++ P TPV +P +
Sbjct: 3623 ITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGT 3682
Query: 1936 THKPVQNPLQTTSQSSKQPPPSIRLPSAQ-----TPNGTDYVASGKSIQTPQSHGTLTAE 1990
T P+ P + ++ + P + R+ S++ TP+ S + S TL +
Sbjct: 3683 T-MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST 3741
Query: 1991 LWDNKVAPPAVLNDISKKL----GPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESG 2046
V+ P ++ + + P++ S + TS +SEG+ + +
Sbjct: 3742 TMS--VSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSS--PTT 3797
Query: 2047 LEIGTDTIQFGAPASNGNENEV---------VPVLSEKSADKIPEPKEQRQK----QPRA 2093
LE GT T+ P S +E + V+S A + P +A
Sbjct: 3798 LE-GTTTM----PMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKA 3852
Query: 2094 GPIKAQKLPDLSPVENKEHKPGPIGK-------ERSLKNRKVKDAQQVEPEGQEKPSPAT 2146
G + + P+ S + ++ PS T
Sbjct: 3853 GSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDT 3912
Query: 2147 VRS-TDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKE--------------SVTDYT 2191
+ T PV T + +V + GT I + S ++ + + T+
Sbjct: 3913 ASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELN 3972
Query: 2192 TPSSSLPNTVATNNTKMEDT---LVNNVPLP----NTLPLPKRETIQ------QSSSLTS 2238
TPS+S +T + +T E T + PL +T P R T + + S TS
Sbjct: 3973 TPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATS 4032
Query: 2239 VPPTTFSLTFK-----MESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANY 2293
P T+ S+T + ES+R + S + P S+ PP T SS+ P
Sbjct: 4033 TPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPP-TTSASSTTVNPEAVTT 4091
Query: 2294 NSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDP 2336
+ P+ + T TT+++ T +T S+P
Sbjct: 4092 MT-----------TRTKPSTRTTSFPTVTTTAVPTNTTIKSNP 4123
Score = 68.6 bits (166), Expect = 9e-11
Identities = 77/261 (29%), Positives = 116/261 (44%), Gaps = 36/261 (13%)
Query: 1742 SSASVPPL------------ASAP-LPPSTSASVPASTSAPLPATL-----TPVPASTSA 1783
S AS PPL AS P +P +T+ SV T P T TPV +ST+
Sbjct: 3893 SIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTAD 3952
Query: 1784 PVPASTLA---PVLASTSAPVPASPLAPVSASASVSA--SVPASTSAAA---ITSSSAPA 1835
PA+T A PV+ ST P++ + + S S + + PA T+AA +T S+AP+
Sbjct: 3953 VFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS 4012
Query: 1836 SAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPA 1895
TP S S + L++ S P ++++ +T TP+ +S P+ IT+ TIP
Sbjct: 4013 -----TPRTTSRGCTTSASTLSATSTPHTSTSV-TTRPVTPSSESSRPS--TITSHTIPP 4064
Query: 1896 SAPTASVPLAP-ASASAPAPAPTPVSA-PNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQ 1953
+ P A P SAS+ P V+ P+ T T P TT +S+
Sbjct: 4065 TFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPT 4124
Query: 1954 PPPSIRLPSAQTPNGTDYVAS 1974
P++ + +G AS
Sbjct: 4125 STPTVPRTTTCFGDGCQNTAS 4145
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 122 bits (307), Expect = 4e-27
Identities = 106/386 (27%), Positives = 193/386 (50%), Gaps = 38/386 (9%)
Query: 336 DDDEQGSNSPKENNSEDQGSKASENNENKKET-DEVSNTK---SSSQIPAQPSVAKVPYG 391
D + S S N+ ++ S+ NE++ E+ E+ N + S ++P P K G
Sbjct: 520 DTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE--KGSRG 577
Query: 392 KGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRR-- 449
S ++S+ + + P+R P R ++ + + RR
Sbjct: 578 SRGSQIDSHSSNSNYHDSWETRSSY---PERDRYPERDNRDQARDSSFERRHGERDRRDN 634
Query: 450 --RQQSEISAAVERARKRREEEERRMEEQRKAACAEKL-KRLDEKLGILEKQPSPEEIRE 506
R Q S + R E + R EE+R ++ +R E+ E+ E RE
Sbjct: 635 RERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERE 694
Query: 507 REREKEREREKELEKEQ--EQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK- 563
RER++ERE+E+ELE+E+ E+ERE+E+E+DRER ++++ + E+E+E++R+ EKER++E+
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Query: 564 EKELERQKEKEKELQKMKEQEKECELEKEREK---LEEKIEPREPNLEPMVEKQESENSC 620
E+E ER++E+E+E ++ +E+E+ E +KERE+ E+K + R+ E E +E N
Sbjct: 755 ERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPR 814
Query: 621 NKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRP---AVLSGYFKQFQKSLPPRFQR 677
+ +E R+ R E +P ++ P+ + P A SG K + L + R
Sbjct: 815 DGHDE----RKSKKRYRNEGSPSPRQS-PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVR 869
Query: 678 QQE----------QMKQQQWQQQQQQ 693
QE + +Q +W+++ ++
Sbjct: 870 PQESRSLSPSHLTEDRQGRWKEEDRK 895
Score = 111 bits (277), Expect = 1e-23
Identities = 82/331 (24%), Positives = 164/331 (49%), Gaps = 31/331 (9%)
Query: 338 DEQGSNSPKENNSEDQGSKASENNENKKETDEV-----SNTKSSSQIPAQPSVAKVPYGK 392
D +G ++ ++ ++ + S++ N ++E+ S +S S+I +
Sbjct: 509 DREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEI------------R 556
Query: 393 GPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQ 452
+ RG LP ++ + + ++ + D ++ R Q
Sbjct: 557 NDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQ 616
Query: 453 SEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRER---ER 509
+ S+ ER R+ + R +QR ++ R DE LE+ EE R +R
Sbjct: 617 ARDSS-FERRHGERDRRDNRERDQRPSSPIRHQGRNDE----LERDERREERRVDRVDDR 671
Query: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
ER RE++ E+E+++ERE+ERE++R+R++EKE+ELE+E+ ++RE E+E+++++E++ +R
Sbjct: 672 RDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDR 731
Query: 570 QKEKEKELQKMKEQEKECELEK-EREKLEEKIEPREPNLEPMVEK---QESENSCNKEEE 625
++E+E ++ +++EKE E E+ ERE+ E+ RE E E+ ++ E ++ E
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWE 791
Query: 626 PVFTRQDSNRSEKEATPVVHETEPESGSQPR 656
+D R ++E + + P G R
Sbjct: 792 DKDKGRDDRREKRE--EIREDRNPRDGHDER 820
Score = 76.3 bits (186), Expect = 4e-13
Identities = 210/1074 (19%), Positives = 389/1074 (36%), Gaps = 161/1074 (14%)
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPS 920
D++ E S ++ + R + + + + + + + + + S +S S
Sbjct: 159 DYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKS 218
Query: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPK 980
KR S S+ K D + S V+S +D + + + K KK S P
Sbjct: 219 PKRKSSPKSSSASKKDRKTSA-------VSSPLLDQQRNSKTNQSK-KKGPRTPSPPPPI 270
Query: 981 PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQR-KEKEGEKA 1039
PE + K ++ + R E R + G RD + +RE+R K + A
Sbjct: 271 PEDIALGK---KYKEKYKVKDRIEEKTRDGKDRG-------RDFERQREKRDKPRSTSPA 320
Query: 1040 EKVTEKVVVKPEKTEKKD------LPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETA 1093
+ + + + + P P + P+P +++ PP++ A +PS +
Sbjct: 321 GQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLS 380
Query: 1094 TLAQKPSQDTEK-PLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPR 1152
+ +K S + P+ E ++ +++ + ++ EK ++ E+ +
Sbjct: 381 SPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQ 440
Query: 1153 PDSRPAVKKESTLPPRTYWKEARE----------RDWFPDQGYRGRGRGEYYSR----GR 1198
SR R ++AR+ RD + R R SR R
Sbjct: 441 SSSRDHRDDREPRDGRDR-RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSR 499
Query: 1199 SYRGSYGGRGRGGRGHTRD---YPQ----YRDNKPRAEHIPSGPLRQREESETRSESSDF 1251
S R ++ R R GR R YP+ Y N R E + +R +E+RSE +
Sbjct: 500 STRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRT-EIRNESRNESRSEIRND 558
Query: 1252 EVVPKRRR-----QRGSETDTDSEIHESASDK---DSL-SKGKLPKREERPENKKPVKPH 1302
+ R R ++GS S+I +S+ DS ++ P+R+ PE +
Sbjct: 559 RMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQAR 618
Query: 1303 SSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRP 1362
S H D R D + P +GR R R R R
Sbjct: 619 DSSFERRHGERDRR----------DNRERDQRPSSPIRHQGRNDELERDERREERRVDRV 668
Query: 1363 STLR--RPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADK-RPPKFERKFDPARER 1419
R R RD + R E + + E R E+ + ++ R + ER+ + RER
Sbjct: 669 DDRRDERARERDRE-RERDRERERERERERDREREKERELERERAREREREREKERDRER 727
Query: 1420 PRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNK 1479
R + R +++ + RERE + E +E
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERERERERERERERERAR--------- 778
Query: 1480 TPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIA 1539
++ + +WE + D +RRE+ E+ D N + G + K+
Sbjct: 779 -----ERDKERERQRDWEDKDKGRD--DRREKREEIREDRNPRD----GHDERKSKKRY- 826
Query: 1540 KRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNER-------------RSGPPS------ 1580
R+ S P RR + P N +NE+ RS PS
Sbjct: 827 -RNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR 885
Query: 1581 --------------KSGKRGPFDDQPAGTTGVD-------LINGSSAHHQEGVPNGTGQK 1619
+S +R + + VD ++ S Q+ + G Q
Sbjct: 886 QGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDII--GHHQS 943
Query: 1620 NSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDD 1679
++++ + ++ K K K+ + + D+ I+ T ED Q
Sbjct: 944 EDRETSDRAHDENKKKAKIQKKPIKKKKEDDVG-------IERGNIETTSEDGQV----- 991
Query: 1680 GFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQ 1739
KK QK+ E++RKK + + +++ A + + + + PP K++ +
Sbjct: 992 ----FSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCN 1047
Query: 1740 AQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSA 1799
++ L + T+ S + P +T + +A P ST +P+ S+
Sbjct: 1048 GKNGI----LEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPL----SS 1099
Query: 1800 PVPASPLAPVSASASVSASVPASTSAAAIT-SSSAPASAPAPTPILASVSTPAS 1852
+P P + + +V A++ A+T+AAA + S+SA + + TP + +T A+
Sbjct: 1100 LLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFAN 1153
Score = 75.9 bits (185), Expect = 5e-13
Identities = 66/347 (19%), Positives = 152/347 (43%), Gaps = 16/347 (4%)
Query: 311 LDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEV 370
L + G G+Q++ ++ N+ D E S+ P+ + ++ ++ + + +
Sbjct: 570 LPEKGSRGSRGSQID-SHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGE 628
Query: 371 SNTKSSSQIPAQPSVAKVPYGKGPSFNQ-ERGTSSHLPPPPKLLAQQHPPPDRQAVPGRP 429
+ + + + +PS G+ + ER + ++ DR+ R
Sbjct: 629 RDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDR- 687
Query: 430 GPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRME-------EQRKAACA 482
+++ + + ++ + ++ E A ER R+R +E +R + E+ +
Sbjct: 688 ----ERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERER 743
Query: 483 EKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQERE-KEREKDRERQQEK 541
++ K + + E++ E RERERE+ERER +E +KE+E++R+ ++++K R+ ++EK
Sbjct: 744 DREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREK 803
Query: 542 EKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIE 601
+E+ +E R+ ERK +K E + ++ +E + + + EK
Sbjct: 804 REEI-REDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 862
Query: 602 PREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETE 648
+ P + S + ++ + + +D KE++ E E
Sbjct: 863 LLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 909
Score = 70.1 bits (170), Expect = 3e-11
Identities = 178/921 (19%), Positives = 301/921 (32%), Gaps = 118/921 (12%)
Query: 515 REKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKE 574
R K + E+ RER + K ++++ E +K+ E KE R +EKE
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKE 125
Query: 575 KELQKMKEQEKECELEK-EREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDS 633
+++ KE+ E E E E E + + + N + V + E K + + +
Sbjct: 126 -DIKITKERTPESEEENVEWETNRDDSDNGDINYD-YVHELSLEMKRQKIQRELMKLEQE 183
Query: 634 NRSEKEATPVVHETEPE---SGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMK----QQQ 686
N ++E + E PE S P P++ +KS P ++ K
Sbjct: 184 NMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSP 243
Query: 687 WQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDP 746
QQ+ Q+ P + + PP P P+ +A ++ ++
Sbjct: 244 LLDQQRNSKTNQSKKKGPRTPSPPP-----------PIPEDIALGKKYKEKYKVKDRIEE 292
Query: 747 RMMSG----------RPAMDIP-PIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARD 795
+ G R D P P P+ R S + S H R
Sbjct: 293 KTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRK 352
Query: 796 HAISLSEPRMLW-----GSDPYPH---AEPQQATTPKATEEPEDVRSEAALDQEQITAAY 847
S S R L + PYP + PQ+ +P P +R + D E+ + ++
Sbjct: 353 RTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSP--MREKGRHDHERTSQSH 410
Query: 848 SVEHNQLE-AHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSA 906
H + E K D ++S E + + S D H D + D +
Sbjct: 411 DRRHERREDTRGKRDREKDSREEREYEQDQSSSRD----HRDDREPRDGRDRRDARDTRD 466
Query: 907 PQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEK 966
+E R S R S + ++ P + RS A +
Sbjct: 467 RRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDA-------------------HDY 507
Query: 967 PKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKE 1026
+EG R + + +S+S R R S+R E N+
Sbjct: 508 RDREG--RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNE------------------S 547
Query: 1027 EREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEK 1086
E R E ++ + +V PEK + + PE ++
Sbjct: 548 RNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Query: 1087 FPSTETATLAQKPS-----------QDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEE 1135
+P + A+ S + E+ P S ++ + + + +EE
Sbjct: 608 YPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDER-----REE 662
Query: 1136 KQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYS 1195
++ ++V + R R R ++ R +E + + R R R
Sbjct: 663 RRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKE 722
Query: 1196 RGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVP 1255
R R R R R H R+ + R+ E R+RE R + E
Sbjct: 723 RDRE-------RDR-DRDHDRERERERERDREKEREREREERERERERERERERERE--- 771
Query: 1256 KRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDN 1315
R R+R E D + E DKD + KREE E++ P H K R +
Sbjct: 772 -RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEG 830
Query: 1316 RLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQW 1375
P R K + P + G + RP +L +++
Sbjct: 831 ----SPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQ 886
Query: 1376 NPRQSEVPKPEDGEPPRRHEQ 1396
+ E KPE E RR+E+
Sbjct: 887 GRWKEEDRKPERKESSRRYEE 907
Score = 64.7 bits (156), Expect = 1e-09
Identities = 55/255 (21%), Positives = 121/255 (47%), Gaps = 16/255 (6%)
Query: 350 SEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPP 409
+ED K K ET V+ + + +P K G + + TS L P
Sbjct: 1153 NEDSHRKCHRTRVEKVETPHVTIEDAQHR---KPMDQKRSSSLGSNRSNRSHTSGRLRSP 1209
Query: 410 PKLLAQQHPPPDRQAVPGRPGPFPSKQQVADED-EIWKQRRRQQSEISAAVERARKRREE 468
A H D Q+ R S+ + + EI +R+ + ++ +
Sbjct: 1210 SNDSA--HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDR 1267
Query: 469 EERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR--EREREKEREREKELEKEQEQE 526
++ R R+++ E +++ + G + + +E E +RE+ERER ++E +++
Sbjct: 1268 QDSRSHSSRRSS-PESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRD 1326
Query: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEK-------ELQK 579
+K+ ++R+R + +E+E E+E++K+R++++ER++ +ER +++++ +++
Sbjct: 1327 ADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIES 1386
Query: 580 MKEQEKECELEKERE 594
+K E + E E ER+
Sbjct: 1387 VKRCEAKLEGEHERD 1401
Score = 60.1 bits (144), Expect = 3e-08
Identities = 45/201 (22%), Positives = 100/201 (49%), Gaps = 28/201 (13%)
Query: 449 RRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRE-- 506
R ++ S + RK R ++ +R E R + + R ++ SPE R+
Sbjct: 1233 RDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSS-----RRSSPESDRQVH 1287
Query: 507 --------REREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKE 558
R+R +ER+R E +RE+ERE+ RQ+E +++ +K+ + R+ ++
Sbjct: 1288 SRSGSFDSRDRLQERDR-------YEHDRERERERRDTRQREWDRDADKDWPRNRDRDRL 1340
Query: 559 RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESEN 618
R++E+E+E +++++ ++E +++ E + +++R++ E + V++ E++
Sbjct: 1341 RERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIES------VKRCEAKL 1394
Query: 619 SCNKEEEPVFTRQDSNRSEKE 639
E + T +DS +KE
Sbjct: 1395 EGEHERDLESTSRDSLALDKE 1415
Score = 58.9 bits (141), Expect = 7e-08
Identities = 70/345 (20%), Positives = 133/345 (38%), Gaps = 74/345 (21%)
Query: 346 KENNSEDQGSKASENNENKKETDEVSNTKSSSQI--PAQPSVAKVP------------YG 391
K+ +D+ K E E++ D KS + PS + P Y
Sbjct: 793 KDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYN 852
Query: 392 KGPSFNQERGTSSHL--PPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRR 449
G N++ S + P + L+ H DRQ GR WK+
Sbjct: 853 SGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQ---GR----------------WKEED 893
Query: 450 RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
R + R+E RR EEQ L EK+ ++KQ EI E R
Sbjct: 894 R------------KPERKESSRRYEEQ----------ELKEKVSSVDKQREQTEILESSR 931
Query: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELE- 568
+ ++ + E + ++ ++++++ + ++K ++K++E +E+ + ++ +
Sbjct: 932 MRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQV 991
Query: 569 ---RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCN---- 621
++ +K+K ++K +++ K + E ++ + R P P+ K+E CN
Sbjct: 992 FSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNG 1051
Query: 622 ------KEEEPVFT--RQDSNRSEKEATPVVH-ETEPESGSQPRP 657
K+E+ F+ + E T H T GS P P
Sbjct: 1052 ILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSP 1096
Score = 54.7 bits (130), Expect = 1e-06
Identities = 177/894 (19%), Positives = 304/894 (34%), Gaps = 130/894 (14%)
Query: 448 RRRQQSEISAAVERARKRREE-----EERRMEEQRKAACAEKLK-RLDEKLGI-LEKQPS 500
RR + ER + +R++ ++R EE E + R EK I + K+ +
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134
Query: 501 PEEIRER-EREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKER 559
PE E E E R+ + + E E R++ Q + +LE+E ++RE E
Sbjct: 135 PESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKRE-EIII 193
Query: 560 KQEKEKELERQK-------EKEKELQKMKEQEKECELEKEREKL---------------- 596
K+E E+ R K K + K K K K+ K
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT 253
Query: 597 --EEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQ 654
+K PR P+ P + + + KE+ V R + + + E + E +
Sbjct: 254 NQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDK 313
Query: 655 PRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPH 714
PR +G Q P + + Q+ + PS T+ P
Sbjct: 314 PRSTSPAG-----QHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTP--- 365
Query: 715 RPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRD 774
PL + P+P H S+ R + P GR H + RR
Sbjct: 366 -PLRRSASPYPSH--SLSSPQRKQSPPRHRSPMREKGR--------HDHERTSQSHDRRH 414
Query: 775 QMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRS 834
+ E +R R++ S R H + ++ + + D R
Sbjct: 415 ERREDTRGKRDREKDSREEREYEQDQSSSR--------DHRDDREPRDGRDRRDARDTRD 466
Query: 835 EAAL-DQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQS 893
L D + + + + D S + R D +S
Sbjct: 467 RRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEES 526
Query: 894 ACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPD--EQRSEPSAGIPKVTS 951
+ + S+ E R + S R+ G + + P+ E+ S S G ++ S
Sbjct: 527 RSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRG-SQIDS 585
Query: 952 RCIDSK--EPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRP 1009
+S + E P+++ R E ++ S E R G R + RE R
Sbjct: 586 HSSNSNYHDSWETRSSYPERD---RYPERDNRDQARDSSFERRHGERDRRDNRE----RD 638
Query: 1010 VRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPA 1069
R S PI+ D E E+R+E+ + ++V ++ + E+ ++D
Sbjct: 639 QRPSSPIRHQGRNDELERDERREER---RVDRVDDR---RDERARERD------------ 680
Query: 1070 PIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAA 1129
E E+ E ++ ++ ++ E ++ E A + ++
Sbjct: 681 ------------RERERDRERE-----RERERERDREREKERELERERARERERER---- 719
Query: 1130 PVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPD-QGYRGR 1188
++E+ E+ +D ER R R K+ + RER+ + + R R
Sbjct: 720 ---EKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERER 776
Query: 1189 GRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIP-SGPLRQREESETRSE 1247
R R R +GR R R+ + D PR H R R E
Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIR-EDRNPRDGHDERKSKKRYRNEGSPSPR 835
Query: 1248 SSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKP 1301
S PKRRR E DS+ + S DK+ K +L + RP+ + + P
Sbjct: 836 QS-----PKRRR----EHSPDSDAYNSGDDKN--EKHRLLSQVVRPQESRSLSP 878
Score = 48.5 bits (114), Expect = 9e-05
Identities = 66/367 (17%), Positives = 140/367 (38%), Gaps = 56/367 (15%)
Query: 331 QLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPY 390
+L+ S + S SPK +S K+S ++ ++T VS+ Q ++ + +K
Sbjct: 205 KLSPSPSLRKSSKSPKRKSSP----KSSSASKKDRKTSAVSSPLLDQQRNSKTNQSK--- 257
Query: 391 GKGPSFNQERGTSSHLPPPP--------KLLAQQHPPPDRQAVPGRPGP-----FPSKQQ 437
++G + PPPP K +++ DR R G F +++
Sbjct: 258 --------KKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQRE 309
Query: 438 VADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEE--QRKAACAEKLKRL------- 488
D+ + S IS+ + + +R +RK + +R
Sbjct: 310 KRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRR 369
Query: 489 ------DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKE 542
L +++ SP R REK R + + ++ E+ + +R +EK+
Sbjct: 370 SASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKD 429
Query: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKERE------KL 596
E+E E+ + ++ + ++E R + ++ + +E ++ RE
Sbjct: 430 SREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDT 489
Query: 597 EEKIEPREP-NLEPMVEKQESENSCNKEEEPVFTRQDSN------RSEKEATPVVHETEP 649
+E +PR+ + + ++ E +E + + + R E T + +E+
Sbjct: 490 KESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRN 549
Query: 650 ESGSQPR 656
ES S+ R
Sbjct: 550 ESRSEIR 556
Score = 47.4 bits (111), Expect = 2e-04
Identities = 61/303 (20%), Positives = 127/303 (41%), Gaps = 35/303 (11%)
Query: 342 SNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERG 401
SN + +DQ + + ++ ++ + + + + ++ + ++ G+ PS R
Sbjct: 1210 SNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSR--IDQLKRGE-PS----RS 1262
Query: 402 TSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQ-------QSE 454
TSS +++ P + V R G F S+ ++ + D R R+ Q E
Sbjct: 1263 TSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQRE 1322
Query: 455 ISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERE 514
++ R + +R E +R+ +K + LD E++ + ER+R+++R+
Sbjct: 1323 WDRDADKDWPRNRDRDRLRERERERE-RDKRRDLDR-----ERERLISDSVERDRDRDRD 1376
Query: 515 R-----EKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
R + E K E + E E E+D E L+KE+ M+K+ + E
Sbjct: 1377 RTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKER-----MDKDLGSVQGFEETN 1431
Query: 570 QKEKEKELQKMKEQEKECELEKEREKLEEKIEP-REPNLEPMV----EKQESENSCNKEE 624
+ E+ + L+ ++ K + E EP + L+ ++ EK+E + K
Sbjct: 1432 KSERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEKMP 1491
Query: 625 EPV 627
+P+
Sbjct: 1492 DPL 1494
Score = 34.7 bits (78), Expect = 1.4
Identities = 61/310 (19%), Positives = 116/310 (37%), Gaps = 65/310 (20%)
Query: 1475 ISGNKTPDLSNQNSSDQANEEWETASESSDFNE-------------RRERDEKKNADLNA 1521
I+ +TP+ S++ N EWET + SD + +R++ +++ L
Sbjct: 129 ITKERTPE------SEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQ 182
Query: 1522 QTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSK 1581
+ + K E ++ K+E++ S+ R+ + P +R+S P S
Sbjct: 183 ENMEKREEIII--KKEVSPEVVRSKLSPSPSLRKSSKSP------------KRKSSPKSS 228
Query: 1582 SGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKE 1641
S + D+ L++ Q+NSK + KK+ P P P
Sbjct: 229 SASK---KDRKTSAVSSPLLDQ--------------QRNSKTNQSKKKGPRTPSPPPPIP 271
Query: 1642 KVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKK 1701
+ AL + Y + D IE+ + D G ++++ + + +
Sbjct: 272 EDIALGK----KYKEKYKVKDR-----IEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQ 322
Query: 1702 EEQVIQVWNKKNANEKGRS-QTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLP-PSTS 1759
I + ++++ G S Q PR + + Q+ + PPL + P PS S
Sbjct: 323 HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLT----PPLRRSASPYPSHS 378
Query: 1760 ASVPASTSAP 1769
S P +P
Sbjct: 379 LSSPQRKQSP 388
Score = 32.7 bits (73), Expect = 5.2
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 1907 ASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTP 1966
A+A+ P P+P+S+ P PP P T T P T + ++ +I + ++ TP
Sbjct: 1085 ATATTPGSTPSPLSSLLP-PPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATP 1143
Query: 1967 NGT 1969
T
Sbjct: 1144 TNT 1146
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 120 bits (302), Expect = 1e-26
Identities = 243/1158 (20%), Positives = 464/1158 (40%), Gaps = 181/1158 (15%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAA-VERARKRREEEE--------RRMEEQRKAACAEKL 485
+++ E+E +QR Q+ E +ER RRE +E RR ++ R+ E+
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 486 KRLDEKLGILEKQPSPEEIRERE--REKEREREKELEKEQEQER-------EKEREKDRE 536
++ +E+ E++ EE RE++ RE+E RE++L +EQE+ER E+E E+ RE
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER-RE 374
Query: 537 RQQEKEKELEKEQEKQREMEKERKQE--KEKELERQKEKEKELQKMKEQEKECELEKERE 594
+Q +E++L +EQ+ +RE + R+Q+ +E++L R+++ +E Q +EQ+ E E+ER
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 595 KLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQ 654
+ + + E RE L+ E++E + +EEE + R E+E + + E +
Sbjct: 435 EQKHEQERREQRLKR--EQEERRDWLKREEE-------TERHEQERRKQQLKRDQEEERR 485
Query: 655 PRPAVL-SGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPP 713
R L ++ Q+ + +R+QE+ ++Q+ ++Q+++ L Q + S+
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE---------- 535
Query: 714 HRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRR 773
+ L + + + L + R + Q + R+ + RR
Sbjct: 536 -QQLRREQEERREQLLKREEEKR--LEQERREQRLKREQEE-----------------RR 575
Query: 774 DQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVR 833
DQ+ E R R+ L E R+ E ++ K E E+ R
Sbjct: 576 DQL----LKREEERRQQRLKREQEERL-EQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 834 SEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQS 893
+ +EQ + + + RE E ++++ L R E+ R
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER---------- 680
Query: 894 ACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRC 953
+E+ ++ E + +R+R S + SE A KV SR
Sbjct: 681 --------------REQELAEEEQEQARERIKSRIPKWQW---QLESEADARQSKVYSRP 723
Query: 954 IDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSET--------RWGPRPSSNR-REE 1004
+ R E++ K+ + + E+ ++ + E +W S R R+
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 1005 VNDRPVRRSGPIKKPVLRDMK-EEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPP 1063
++ RP P+++ R ++ EER+QR+++ + E+ ++ + E+ ++
Sbjct: 784 LSARP-----PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF----- 833
Query: 1064 PPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVN 1123
+ +Q + +Q E + + +Q+ +D + Q+E K
Sbjct: 834 -LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK------WRWQLEEERKRRR 886
Query: 1124 QQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQ 1183
A P ++E+ + E+ + ++ E R + ++E R + +E + +
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 1184 GYRGRGRGEYYSRGRSYRGSYGGRGRG----GRGHTRDYPQYRDNKPRAEHIPSGPLRQR 1239
R R E R R YR + + G + Q R+ K R E L+Q
Sbjct: 947 EREKRRRQE---RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE----ELQQE 999
Query: 1240 EESETRSESSDFEVVPKRRRQ---RGSETDTDSEIHESASDKDSLSKGKLPKREE--RPE 1294
EE R E KRRRQ R + + E ++ K +L +RE R E
Sbjct: 1000 EEQLLREERE------KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 1295 NKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDD-KAKPGFLPKGEPTRRGRGGTFRRGGR 1353
+ + + R + LE+ Y ++++ + + L + EP +R R R+
Sbjct: 1054 EELQQEEEQLLGEERETR-RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Query: 1354 DPGGRPSRPSTLRRP-----------AYRDNQWNPRQSEVPKPEDGEPPRR--------- 1393
+ + LR YR+ + ++ E E+ E RR
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 1394 -------HEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPP--RFRRLRERE 1444
EQ + +KR + ER++ E R++R R +D+ +++ E+E
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 1445 AASKSNEVVAVPTNGTVN-NVAQEPVNTLGDISGNKTPD--LSNQNSSDQANE--EWETA 1499
A + N+V G N Q + L D + L Q D+ E W+
Sbjct: 1233 NAVRDNKVYC---KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
Query: 1500 SESSDFNERRERDEKKNA 1517
E+ ER+E+K A
Sbjct: 1290 DRHFPEEEQLEREEQKEA 1307
Score = 111 bits (277), Expect = 1e-23
Identities = 101/379 (26%), Positives = 186/379 (49%), Gaps = 28/379 (7%)
Query: 330 EQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAK-V 388
++L F +++EQ + +++ E+ E ++ ++ + K Q+ + +
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 389 PYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIW--- 445
Y K Q R L + L ++ R+ R + ++Q+ E+E
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ--YREEEQLQQEEEQLLRE 946
Query: 446 --KQRRRQQSEISAAVERARKRREEEERRME-EQRKAACAEKLKRLDEKLGILEKQPSPE 502
++RRRQ+ E ++ +++EE+ E E+R+ EK R +E+L E+Q E
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 503 EIREREREKERERE----KELEKEQEQ----EREKEREKDRERQQEKEKELEKEQEKQRE 554
E RE+ R +E ER+ EL++E+EQ EREK R ++RERQ +E+EL++E+E+
Sbjct: 1007 E-REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL-- 1063
Query: 555 MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQ 614
+ +ER+ + +ELERQ KE+ELQ+ +EQ E EK R + RE E Q
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR------QERERQCREEEELQ 1117
Query: 615 ESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPR 674
+ E +EE RQ+ R +E V E E +P +Q+++
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE--EE 1175
Query: 675 FQRQQEQMKQQQWQQQQQQ 693
Q+++EQ+ +++ ++++Q+
Sbjct: 1176 LQQEEEQLLREEQEKRRQE 1194
Score = 110 bits (276), Expect = 2e-23
Identities = 218/1177 (18%), Positives = 445/1177 (37%), Gaps = 168/1177 (14%)
Query: 419 PPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVE-RARKRREEE---ERRME 474
P DRQ P ++Q E E +QSE +E R R+RR+EE +R+
Sbjct: 124 PRDRQL---EEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW 180
Query: 475 EQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE----REKEREREKELEKE------QE 524
++R+ AE+ + K E+ P E++R RE R K RE +++ +E QE
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 525 QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE---KELERQKEKEKELQKMK 581
+E ++ R+++ ++E+EK E+E ++QRE+++E +Q ++ +EL R++++E++ Q+
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 582 EQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEAT 641
+E++ ++E E+ E++ E RE +++ E +E+E +Q E+E
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 642 PVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVP 701
E E + + ++ Q+ + R+++Q++++Q +++QQ Q +
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 702 SQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPR-WLMMQSYMDPRMMSGRPAMDIPPI 760
+ + Q L + R WL + + R
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR-------- 472
Query: 761 HPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQA 820
K ++RDQ E R+ + L E E Q+
Sbjct: 473 -------KQQLKRDQEE--------------ERRERWLKLEEEE---------RREQQER 502
Query: 821 TTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVE 880
+ E E+ R + QE E +L+ R SE Q L R E
Sbjct: 503 REQQLRREQEERREQRLKRQE--------EEERLQQ-------RLRSEQQ----LRREQE 543
Query: 881 DVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRS 940
+ R + + ++ L QEER + KR ++ E+R
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQL-----LKREEERRQQRLKREQEERL 598
Query: 941 EPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSN 1000
E +E +ER E++ ++E ++ E + + KSE + R
Sbjct: 599 EQRL-----------KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 1001 RREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPP 1060
RRE+ RR +K+ + E+R +R+ +E + +++ E+ + + K +
Sbjct: 648 RREQQE----RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI-- 701
Query: 1061 PPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVK 1120
P Q +S Q + P + ++ ++ + E Q E
Sbjct: 702 ------PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH 755
Query: 1121 TVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWF 1180
Q+ + Q E+ + R R +RP ++++ R ++ RE+ +
Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERG----RQRLSARPPLREQRERQLRAEERQQREQRFL 811
Query: 1181 PDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQRE 1240
P++ + + R + R + + R + + D + R+R
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE------RRRS 865
Query: 1241 ESETRSESSDFEVVPKRRRQRGS-------ETDTDSEIHESASDKDSLSKGKLPKREERP 1293
+ + R + +++ +R+R+R + + E +++ L + + KR +
Sbjct: 866 QEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQE 925
Query: 1294 ENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGR 1353
+ ++ + + + + + R + R+ K L + E G RR
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 1354 DPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKF 1413
R YR+ + ++ E E+ E RR E +ER++
Sbjct: 986 ------------REKKYREEEELQQEEEQLLREEREKRRRQE-------------WERQY 1020
Query: 1414 DPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLG 1473
E + + ++K RRL+ERE + E + QE LG
Sbjct: 1021 RKKDELQQEEEQLLREEREK----RRLQERERQYREEE-----------ELQQEEEQLLG 1065
Query: 1474 -DISGNKTPDLSNQNSSDQ--ANEEWETASESSDFNERRERDE--KKNADLNAQTVVKVG 1528
+ + +L Q ++ EE + E + R+ER+ ++ +L + +
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 1529 ENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGR 1565
E +R+ +R + + V ++ + P+ R
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Score = 103 bits (257), Expect = 2e-21
Identities = 105/405 (25%), Positives = 182/405 (44%), Gaps = 45/405 (11%)
Query: 309 DNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETD 368
+ L E E + E Y E+ ++EQ +E + + ++ ++ +
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 369 EVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGR 428
E + + Q K Y + QE +LL ++ RQ +
Sbjct: 971 EQLLGEEPEKRRRQEREKK--YREEEELQQEE---------EQLLREEREKRRRQEWERQ 1019
Query: 429 PGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQ---------RKA 479
+ K ++ E+E Q R++ E ER R+ REEEE + EE+ R+
Sbjct: 1020 ---YRKKDELQQEEE---QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 480 ACAEKLKRLDEKLGILEKQ---PSPEEIREREREKEREREKELEKEQEQ----EREKERE 532
E+ R +E+L E+Q PE+ R +ERE++ E+EL++E+EQ EREK R
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 533 KDRERQQEKEKELEKEQEK--QREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELE 590
++ ERQ +E+E+++E+E+ + E EK R+QE LERQ +E+ELQ+ +EQ E E
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQE----LERQYREEEELQQEEEQLLREEQE 1189
Query: 591 KEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
K R++ E + E L+ KQ + + + + + ++ E E
Sbjct: 1190 KRRQERERQYR-EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENE 1248
Query: 651 SGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ---WQQQQQ 692
Q + L +Q Q+ L QQE+ ++Q+ WQQ+ +
Sbjct: 1249 QFRQLEDSQLRD--RQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291
Score = 97.8 bits (242), Expect = 1e-19
Identities = 215/1078 (19%), Positives = 432/1078 (40%), Gaps = 130/1078 (12%)
Query: 414 AQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRM 473
A++ RQ + RP P ++Q + ++++R+Q + E+ ++RR+ ER
Sbjct: 773 AEEKSERGRQRLSARP---PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 474 EEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKER-- 531
E Q E+L+R + + E++ +E +ER R +E+ R+++ + E+ER++ R
Sbjct: 830 ELQFLEE-EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 532 -----------EKDRERQQEKEKELEKEQ-EKQREMEKERKQEKEKELERQKE----KEK 575
K+++ QE+E+EL++E+ EK+R E+ER+ +E++L++++E +E+
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948
Query: 576 ELQKMKEQEKECELEKEREKLEEKI---EPREPNLEPMVEKQESENSCNKEEEPVFTRQD 632
E ++ +E+E++ +K+ ++ EE++ EP + + +K E +EEE + R++
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL-REE 1007
Query: 633 SNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQ 692
+ ++ + + E + + K+ R Q ++ Q ++++ QQ++
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKR-------RLQERERQYREEEELQQEE 1060
Query: 693 QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR 752
+ +L + ++ +R + Q Q L +P Q R R
Sbjct: 1061 EQLLGEERETRRRQEL--ERQYRKEEELQQEEEQLLRE---EPEKRRRQE----RERQCR 1111
Query: 753 PAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPY 812
++ ++ + RR Q + R R+ E L +P
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQ------------ELERQYREEEEVQQEEEQLLREEP- 1158
Query: 813 PHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQ 872
+ ++ + E E+++ E +EQ+ E + + RE E Q Q
Sbjct: 1159 --EKRRRQELERQYREEEELQQE----EEQLLR----EEQEKRRQERERQYREEEELQRQ 1208
Query: 873 KFLSR-SVEDVRPH---HTDANNQSACFEAPDQKTLSAPQE-ERISAVESQPSRKRSVSH 927
K R ED R + ++A D K +E E+ +E R R
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENA---VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQ 1265
Query: 928 GSNHTQKPDEQRS-EPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYK 986
H ++R E + R +E +ER E+K K +S E + + + +
Sbjct: 1266 DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE--EKQLLRE 1323
Query: 987 SKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMK-EEREQRKEKEGEKAEKVTEK 1045
+ E R REE R P+++ RD K E E R +++G K + E+
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQE-RDRKFREEELRHQEQGRKF--LEEE 1380
Query: 1046 VVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAE-KFPSTETATLAQKPSQDTE 1104
++ ++ E+K L + ++ Q ++ + + KF E Q+ +
Sbjct: 1381 QRLRRQERERKFL-------KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 1105 KPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKEST 1164
+ + V + E QQ K ++ + + ++ + R +++E
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 1165 LPPRTYWKEARERDWFPDQGYRGRGRGEY----YSRGRSYRGSYGGRGRGGRGHTRDYPQ 1220
L + ++ RE++ + R E R R + R RG R Q
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR--RQ 1551
Query: 1221 YRDNKPRAEHIPSGPLRQ-REESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKD 1279
RD K R E LRQ REE + + D + + ++ R E + + D+
Sbjct: 1552 DRDRKFREEE----QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE-----RKFMEDEQ 1602
Query: 1280 SL--SKGKLPKREERP----ENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGF 1333
L +G+ R+ER E+++ ++ + R L E+P +R ++
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE---- 1658
Query: 1334 LPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRR 1393
+ R R FR + + LRR RD ++ + ++ + E R
Sbjct: 1659 ----QQLRHDRDRKFRE--EEQLLQEGEEQQLRRQE-RDRKFREEEQQLRRQE------R 1705
Query: 1394 HEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNE 1451
+F+ R + ERKF RE + ++ T + + R+R++ E E E
Sbjct: 1706 ERKFLQEEQQLRRQELERKF---REEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Score = 93.2 bits (230), Expect = 3e-18
Identities = 77/365 (21%), Positives = 177/365 (48%), Gaps = 28/365 (7%)
Query: 330 EQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVP 389
+QL+ + D + ++ ++Q K E+ + + + + + +
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 390 YGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRR 449
+ +++ L P+L Q+ ++Q R F ++Q+ E E +Q R
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQER---EQQLRHDRDRKFREEEQLLQEGEE-QQLR 1685
Query: 450 RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
RQ+ + E + RR+E ER+ ++ + ++L+R + L ++ E++R +ER
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745
Query: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
++ E++L E+E+++ + +E+DR+ ++E++ E+E+++ R E +RK +E++L +
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805
Query: 570 QKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFT 629
++E+ Q+++ Q+++ + E E+L+ +E +E L ++Q + EE T
Sbjct: 1806 EREE----QQLRPQQRDGKYRWEEEQLQ--LEEQEQRLRQERDRQ------YRAEEQFAT 1853
Query: 630 RQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ 689
++ S R E+E + + E + Q R L + R Q+++EQ +Q +
Sbjct: 1854 QEKSRREEQE----LWQEEEQKRRQERERKL--------REEHIRRQQKEEQRHRQVGEI 1901
Query: 690 QQQQG 694
+ Q+G
Sbjct: 1902 KSQEG 1906
Score = 90.1 bits (222), Expect = 3e-17
Identities = 94/400 (23%), Positives = 179/400 (44%), Gaps = 73/400 (18%)
Query: 307 KFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKE 366
K + L E E + E Y E+ ++EQ +E + + + ++
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Query: 367 TDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVP 426
+E + + Q + Y + QE +LL ++ RQ +
Sbjct: 1029 EEEQLLREEREKRRLQERERQ--YREEEELQQEE---------EQLLGEERETRRRQELE 1077
Query: 427 GRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQ---------R 477
+ + ++++ E+E Q R++ E ER R+ REEEE + EE+ R
Sbjct: 1078 RQ---YRKEEELQQEEE---QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 478 KAACAEKLKRLDEKLGILEKQ---PSPEEIREREREKEREREKELEKEQEQ---EREKER 531
+ E+ R +E++ E+Q PE+ R +E E++ E+EL++E+EQ E +++R
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Query: 532 EKDRERQQEKEKELEKEQEKQR--------------EMEKE------------RKQEKEK 565
++RERQ +E+EL++++ KQR E EKE R+ E+ +
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Query: 566 ELE----RQKEKEKELQKM--KEQEKECELEKEREKLEEKIEPREPNLEPMVEK------ 613
+LE R ++ +++LQ + ++QE++ E E+ R + ++ P E LE +K
Sbjct: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD 1311
Query: 614 ---QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
QE + +E E RQ+++R +E ++ E E +
Sbjct: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Score = 87.8 bits (216), Expect = 1e-16
Identities = 195/1095 (17%), Positives = 399/1095 (36%), Gaps = 197/1095 (17%)
Query: 413 LAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERR 472
L ++H R+ +++++ W+ + +++ + +R R++E +RR
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Query: 473 MEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKE-------------------- 512
+EQ EK +R + +L E++ + + +E E+ ++
Sbjct: 732 RQEQE-----EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 513 -----REREKELEKEQEQERE-----KEREKDRERQQEKEKE-----LEKEQEKQREMEK 557
+RE++L E+ Q+RE +E EK++ R+Q +E+E LE+E++ QR
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
Query: 558 ERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK---- 613
++ QE+E L+ +E+ + ++ ++Q+ +LE+ER++ + + P L+ + K
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK-PALQEQLRKEQQL 905
Query: 614 -QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLP 672
QE E +EE RQ+ R +E + E E + +Q++K
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD-- 963
Query: 673 PRFQRQQEQM----KQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHL 728
+ Q+++EQ+ +++ +Q++++ + Q + + Q + +
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Query: 729 ASMGFDPRWLMMQSYMDPRMMS-GRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFE 787
+ + L+ + R+ R + + +Q+ G + +
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQ---------QEEEQLLGEERETRRRQ 1074
Query: 788 HIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAY 847
+ R R E L +P ++ + EE + + ++ +
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 848 SVEHNQLE----AHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKT 903
+E E + +RE E + ++ L R + + +++
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE-----------LQQEEEQL 1183
Query: 904 LSAPQEERISAVESQPSRKRSVSHGSNHTQKPDE-QRSEPS-AGIPKVTSRCIDSK---E 958
L QE+R E Q + + + DE QRS+ P+ + D+K +
Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243
Query: 959 PIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKK 1018
E + + ++ +R + + + + + R R RR + DR +
Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER--DREQERRRWQQRDRHFPEEEQL-- 1299
Query: 1019 PVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPP 1078
ERE++KE + + EK +++ E+ EK+
Sbjct: 1300 --------EREEQKEAKRRDRKSQEEKQLLREEREEKRRR-------------------- 1331
Query: 1079 PIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQP 1138
Q KF E Q + E+PL + + ++ ++Q
Sbjct: 1332 --QETDRKFREEE-----QLLQEREEQPLR-----------RQERDRKFREEELRHQEQG 1373
Query: 1139 EKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYS--- 1195
K + ++ + R + R +K+E L + RE+ D+ + R + S
Sbjct: 1374 RKFLEEEQRLRRQERE-RKFLKEEQQLR-----CQEREQQLRQDRDRKFREEEQQLSRQE 1427
Query: 1196 RGRSYR--GSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEV 1253
R R +R R R + Q R + R L++REE + + D +
Sbjct: 1428 RDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Query: 1254 VPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRI 1313
+ + ++ R E D E R + PE K
Sbjct: 1488 LEEEQQLRRQERDRKFREQE--------------LRSQEPERK----------------- 1516
Query: 1314 DNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDN 1373
LE+ + + FL + + RR G RR RD R R R +
Sbjct: 1517 ---FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD---RKFREEEQLRQEREEQ 1570
Query: 1374 QWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDK 1433
Q + ++ + + + RR EQ ERKF ++ RRQ + RQ++
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQ-------------ERKFMEDEQQLRRQEGQQQLRQER 1617
Query: 1434 PPRFRR----LRERE 1444
+FR L+ERE
Sbjct: 1618 DRKFREDEQLLQERE 1632
Score = 87.8 bits (216), Expect = 1e-16
Identities = 105/455 (23%), Positives = 206/455 (45%), Gaps = 63/455 (13%)
Query: 290 EPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQ-LNFSDDDEQGSNSPKEN 348
E ER + +L+ ++ L + D + + ++ E+ F ++++Q +E
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 349 NS-EDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSH-- 405
E++ E + +E +++ + Q+ Q K + QER
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 406 ----LPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRR------------ 449
P K L ++ +Q R F ++Q E +QRR
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQ----RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 450 ----RQQSEISAAVERARKRREEEE--RRMEEQRKAACAEKLKRLDEKLGILEKQ----- 498
R++ ++S ER RK R EE+ RR E++RK E+ R E L ++
Sbjct: 1563 LRQEREEQQLSRQ-ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 499 -PSPEEIREREREK--EREREKELEKEQEQEREKEREK----DRERQQEKEKELEKEQEK 551
+ ++ERE ++ +ER+++ +E+ Q R +ERE+ DR+R+ +E++L +E E+
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
Query: 552 Q--REMEKERKQEKEKELERQKEKEKELQKMKEQEKECELE---KEREKLEEKIEPREPN 606
Q R E++RK +E++ R++E+E++ + ++Q + ELE +E E+L ++ E +
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741
Query: 607 LEPMVEK-QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPES-GSQPRPAVLSGYF 664
+ K E E + EE RQ+ +R +E + E E + SQ
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD------- 1794
Query: 665 KQFQKSLPPRFQRQQEQMKQQQ------WQQQQQQ 693
++F++ R +R+++Q++ QQ W+++Q Q
Sbjct: 1795 RKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ 1829
Score = 86.3 bits (212), Expect = 4e-16
Identities = 166/784 (21%), Positives = 311/784 (39%), Gaps = 136/784 (17%)
Query: 323 QMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKET--------DEVSNTK 374
++E Y E+ ++EQ +E +++ + E E +++ D+ S+ K
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK 1224
Query: 375 SSSQIPAQPSVA--KVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPF 432
+ + +V KV Y KG Q R L + D Q + G
Sbjct: 1225 WQWEPEKENAVRDNKV-YCKGRENEQFRQLED------SQLRDRQSQQDLQHLLG----- 1272
Query: 433 PSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKL 492
+QQ D ++ +RRR Q +R R EEE+ EEQ++A KR D K
Sbjct: 1273 --EQQERDREQ---ERRRWQ-------QRDRHFPEEEQLEREEQKEA------KRRDRK- 1313
Query: 493 GILEKQPSPEEIREREREKEREREKELEKEQEQEREKE----REKDRE------RQQEKE 542
EKQ EE E+ R +E +R+ E++ QERE++ +E+DR+ R QE+
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKEL-----QKMKEQEKECELEKEREKLE 597
++ +E+++ R E+ERK KE++ R +E+E++L +K +E+E++ ++ K
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 598 EKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRP 657
E+ E V +QE E +EE+ + RQ+ +R +E ++ E E +
Sbjct: 1434 EE--------EQQVRRQERERKFLEEEQQL--RQERHRKFREEEQLLQEREEQ------- 1476
Query: 658 AVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPL 717
+ ++ +F +++Q+++Q+ ++ ++ Q + SQ P + L
Sbjct: 1477 -------QLHRQERDRKFLEEEQQLRRQERDRKFRE----QELRSQ-------EPERKFL 1518
Query: 718 YQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQME 777
+ Q H Q R + + R G+ + R+ + E
Sbjct: 1519 EEEQQLHRQQ------RQRKFLQEEQQLRRQERGQQRR------------QDRDRKFREE 1560
Query: 778 GSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAE-PQQATTPKATEEPEDVRSEA 836
+ ++R RD L E ++ E QQ + ++ R
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 837 ALDQEQITAAYSVE--HNQ------LEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTD 888
+ EQ+ + H Q LE P+ R+ E Q++ R + +
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQ--LRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 889 ANNQSACFEAPDQK------TLSAPQEERISAVESQPSRKRSVSHG-------SNHTQKP 935
Q + D+K L + ER E Q R++ + T++
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 936 DEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGP 995
+R E I + + +E R +E+ +K + E+ +S+ R
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 996 RPSSNR--REEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKT 1053
R REE RP +R G + + EE+EQR +E ++ + E+ + EK+
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ-EKS 1857
Query: 1054 EKKD 1057
+++
Sbjct: 1858 RREE 1861
Score = 64.3 bits (155), Expect = 2e-09
Identities = 49/214 (22%), Positives = 105/214 (49%), Gaps = 43/214 (20%)
Query: 512 EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKEL---E 568
+ E+ + ++ +++ +E+D+ R + ++++LE+E ++R ++++QE+E+EL E
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRR---RQKRQEQERELAEGE 152
Query: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVF 628
Q EK++ L++ Q ++ EL ++R++ +E+ E R ++E SC E F
Sbjct: 153 EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR--------AEEEQLQSCKGHETEEF 204
Query: 629 T-----------------RQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSL 671
R++ + +E V + E E + R VL ++ Q+
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 672 PPR---FQRQQEQM---------KQQQWQQQQQQ 693
P R Q ++EQ+ +++Q ++QQQQ
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 118 bits (296), Expect = 7e-26
Identities = 90/238 (37%), Positives = 108/238 (45%), Gaps = 28/238 (11%)
Query: 1752 APLPPSTSASVPASTSAP--LPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPV 1809
+PLP P S S P +P VP S APVP S L PV +TS P P+ PLAPV
Sbjct: 197 SPLPAPICPPAPGSASVPHSVPDAFQ-VPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPV 255
Query: 1810 SASA----------------SVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASV 1853
A A SVSASV A+A S P SAPAP P+ VS P
Sbjct: 256 PALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLA 315
Query: 1854 TILASA--SIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASA 1911
I A S P L A T P PA++ PAAP + +P P++ P P
Sbjct: 316 LIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLI-- 373
Query: 1912 PAPAPTPVSAPNPAP---PAPAQTQAQTHK--PVQNPLQTTSQSSKQPPPSIRLPSAQ 1964
PA APTPV AP PAP PAP A T P P+ + S+ P+ + P+ Q
Sbjct: 374 PAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQ 431
Score = 94.0 bits (232), Expect = 2e-18
Identities = 190/784 (24%), Positives = 281/784 (35%), Gaps = 129/784 (16%)
Query: 1775 TPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASV----------SASVPASTS 1824
T + A+ VP P++ + +P+PA P SASV SVPA
Sbjct: 173 TFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVP 232
Query: 1825 AAAITSSSAPASAPAPTPILASV----STPASVTILASASIPILASALASTSAPTPAPAA 1880
+ + S PAP+P LA V P SV L S S P+ SA S P PA+
Sbjct: 233 HSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSA----SVLVPVPAS 288
Query: 1881 SSPAAPV-ITAPT-IPASAPTASVPLAPASASAPAPAPTPVSAPNPAP---PAPAQTQAQ 1935
+ P+ PV ++AP P S P ++ PLA A P APT V AP P P P PA T
Sbjct: 289 APPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPA 348
Query: 1936 THKPVQNPLQTTSQSSKQPPPSIRLPS-AQTPNGTDYVASGKSIQTPQSHGTLTAELWDN 1994
P P+ T + SS P +P+ A TP + P T
Sbjct: 349 APAPPSVPMPTPTPSSGPPSTPTLIPAFAPTP-----------VPAPTPAPIFTPAPTPM 397
Query: 1995 KVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEI-GTDT 2053
A PA + P S P P S S ++ AP+ + + G + +
Sbjct: 398 PAATPAAI--------PTSAPIPASFSL-SRVCFPAAQAPAMQKVPLSFQPGTVLTPSQP 448
Query: 2054 IQFGAPASNGNENEV--------------VPVLSEKSADKI-------PEPKEQRQKQPR 2092
+ + P S G V +PVL D+ PE +
Sbjct: 449 LVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSV 508
Query: 2093 AGP---------IKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPS 2143
A P ++ +LP SP + +P P G L + + A +
Sbjct: 509 ARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLL 568
Query: 2144 PATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVAT 2203
PA S+ P + + +E TE GT ++ S + + + S +P +++
Sbjct: 569 PAPSGSSAPPHPAKMPSGTEQQTE-GTSVTFSPLKSPPQLEREMAS-PPECSEMPLDLSS 626
Query: 2204 NNTKMEDTLVNNVPLPN---TLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENS 2260
+ + + +PLPN T P+P + SS T S R
Sbjct: 627 KSNRQK------LPLPNQRKTPPMPVLTPVHTSSK-------ALLSTVLSRSQRTTQAAG 673
Query: 2261 PNVREKGSPVTSTAPPIATGVSSSASG-PSTANYNSFSSASMPQIPVASVTPTASLSGAG 2319
NV S + ST+ P +G PST NS + + S P + A
Sbjct: 674 GNVT---SCLGSTSSPFVIFPEIVRNGDPSTWVKNSTA--------LISTIPGTYVGVAN 722
Query: 2320 TYTTSSLSTKSTT---TSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQ-QQQNP 2375
S L K DP ++ K +P + P + + A+ Q
Sbjct: 723 PVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTV 782
Query: 2376 QVYVSQSAAAQIPAFYMDTSHLFN-TQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIY 2434
+ Y A +P L+ T A + P +PTS Q +P+ +
Sbjct: 783 KRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVN--------GKPTSTQVLPVG-W 833
Query: 2435 APLQGQHQAQ-LSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNF 2493
+P HQA LS+G +S A +L S P R P + S S + S A+H
Sbjct: 834 SP---YHQASLLSIG----ISSAGQLTPSQGAPIR--PTSVVSEFSGVPSLSSSEAVHGL 884
Query: 2494 PTVQ 2497
P Q
Sbjct: 885 PEGQ 888
Score = 93.6 bits (231), Expect = 2e-18
Identities = 143/500 (28%), Positives = 184/500 (36%), Gaps = 69/500 (13%)
Query: 1735 TGIQQAQSSASVP----PLAS----APLPPSTSA--------SVPASTSAPLPATLTP-- 1776
+G+ Q + SVP PLA AP PPS SV AS P+PA+ P
Sbjct: 234 SGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSG 293
Query: 1777 -VPASTSAPVPAS--TLAPVLASTSAPVPASP----LAPVSASASVSASVPASTSAAAIT 1829
VP S AP P S AP LA APVP S LAPV V A +PAST AA
Sbjct: 294 PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPV--PTPVLAPMPASTPPAAPA 351
Query: 1830 SSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVIT 1889
S P P PTP STP + A +P A T APTP PAA+ A P T
Sbjct: 352 PPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIP--T 407
Query: 1890 APTIPASAPTASVPLAPASASA---------PAPAPTPVSAPNPAPPAPAQTQAQTHKPV 1940
+ IPAS + V A A A P TP S P P P+ Q + +
Sbjct: 408 SAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTP-SQPLVYIPPPSCGQPLSVATL 466
Query: 1941 QNPLQTTSQSSKQPPPSIR----LPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKV 1996
L +S + PS LP S+ P + + L N++
Sbjct: 467 PTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRL 526
Query: 1997 APPAVLNDISKKLGPISPPQP----------PSVSAWNKPLTSFGSAPSSEGAKNGQESG 2046
+ + + P P P V +PL S S+ SG
Sbjct: 527 PCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSG 586
Query: 2047 LEIGTD--TIQFG---APASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKL 2101
E T+ ++ F +P E P SE D K RQK P K +
Sbjct: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDL--SSKSNRQKLPLPNQRKTPPM 644
Query: 2102 PDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPS----PATVRSTDPVT-TK 2156
P L+PV RS + + G P VR+ DP T K
Sbjct: 645 PVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVK 704
Query: 2157 ETKAVSEMSTEIGTMISVSS 2176
+ A+ +ST GT + V++
Sbjct: 705 NSTAL--ISTIPGTYVGVAN 722
Score = 44.7 bits (104), Expect = 0.001
Identities = 58/273 (21%), Positives = 106/273 (38%), Gaps = 39/273 (14%)
Query: 337 DDEQGSNSPKENN-SEDQGSKASENNENKKETDEVSNTKSSSQIPAQP--SVAKVPYG-- 391
DD S PK+ +++ S+ + K S+ ++P+ P S K P G
Sbjct: 1108 DDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVVRSSHRPKCRKLPSDPQESTKKSPRGAS 1167
Query: 392 -KGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRR 450
G N RG H P P+ Q+ PG+ + +E + K+ +
Sbjct: 1168 DSGKEHNGVRGKHKHRKPTK---------PESQS-PGK------RADSHEEGSLEKKAKS 1211
Query: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR----E 506
+ V R R Q + C+ D +G E P+ EE
Sbjct: 1212 SFRDFIPVVLSTRTR---------SQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTP 1262
Query: 507 REREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM----EKERKQE 562
+R K R+ +++ + ++K R + +E+ E R+M E+E ++E
Sbjct: 1263 AKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEE 1322
Query: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREK 595
+E L+R+K + ++ +K + E E E E+ +
Sbjct: 1323 EEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRR 1355
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 117 bits (293), Expect = 2e-25
Identities = 83/310 (26%), Positives = 163/310 (52%), Gaps = 30/310 (9%)
Query: 415 QQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRME 474
+++ DR + GR +++ E E +R+RQ ER R+R+ E ER +
Sbjct: 197 KENKTEDRHSERGR------ERERERETETETERKRQTDR-----ERDRQRKTEREREKQ 245
Query: 475 EQRKAACAEKLKRLDEKLGILEK-------QPSPEEIREREREKEREREKELEKEQEQER 527
+R+ A + +R E+ ++ Q E +R+R++ ER++E E+++E++R
Sbjct: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305
Query: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC 587
E+ERE++R R++E+E+E E+E+E+QRE E++R++E+E++ +RQ E ++E + +E
Sbjct: 306 ERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR 365
Query: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQ-DSNRSEKEATPVVHE 646
+ E+ERE+ RE + + E++E E +++ + RQ + +R + T E
Sbjct: 366 QAERERER------ERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419
Query: 647 TEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSS 706
E + S+ G ++ QK R + ++ Q +Q +Q+++ + P S
Sbjct: 420 REKDRESERGRE--RGREREKQKG---RERDRERQTDRQAGRQRKRSTLYVNPPPRTARS 474
Query: 707 STVPPPPHRP 716
V P+RP
Sbjct: 475 GVVQSDPNRP 484
Score = 112 bits (281), Expect = 4e-24
Identities = 96/385 (24%), Positives = 175/385 (45%), Gaps = 67/385 (17%)
Query: 276 KGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFS 335
+G RGR E ER ++ D+ E + + + + N
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR-------QKEREREKNRQ 186
Query: 336 DDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPS 395
+ E+ KEN +ED+ S+ E ++ET+ + K +
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQT------------------ 228
Query: 396 FNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEI 455
++ER + A++ +R+ + +++ D D + R R+Q E
Sbjct: 229 -DRERDRQRKTEREREKQAERERASERETERDK-----ERERERDRD---RDRDRRQKER 279
Query: 456 SAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERER 515
+R R+RR E +R E +R+ R E+ E++ RERERE+ERER
Sbjct: 280 ERQTDRKRQRRTERDRETERKRE--------RQRER----ERERERNRKRERERERERER 327
Query: 516 EKELEKEQEQEREKER------EKDRERQQEKEKELEKEQEKQREMEKER---------K 560
E++ E E+++E+E+ER E DRER ++ +E ++ E++RE E+ER +
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 561 QEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSC 620
+E++++ +RQKE+E++ +K ++ ++E E ++EREK E RE E EKQ+
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER--EKQKGRERD 445
Query: 621 NKEEEPVFTRQDSNRSEKEATPVVH 645
+ + T + + R K +T V+
Sbjct: 446 RERQ----TDRQAGRQRKRSTLYVN 466
Score = 112 bits (281), Expect = 4e-24
Identities = 95/367 (25%), Positives = 171/367 (46%), Gaps = 49/367 (13%)
Query: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA 480
+RQ R +Q E E +Q RR++ + R E R E +R+
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDR----- 535
+ KR ++ +++ E ++ ERE+ ERE E +KE+E+ER+++R++DR
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Query: 536 ------------ERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQ 583
ER +E E++ E+++E++RE E+ RK+E+E+E ER++E+++E ++ +E+
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 584 EKE------CELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
E+E E+++ER + + R+ E E++ S + EE R + E
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKE 399
Query: 638 KEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLP 697
+E +TE + Q KQ ++ +R +E+ ++++ Q+ +++
Sbjct: 400 RE-----RQTEKDRDGQRETE------KQREREKDRESERGRERGREREKQKGRERDRER 448
Query: 698 QT---VPSQPSSST--VPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMS-- 750
QT Q ST V PPP +Q P + G RW S DP+ S
Sbjct: 449 QTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR-PTRGI--RW--KSSPEDPKAASTR 503
Query: 751 ---GRPA 754
GRPA
Sbjct: 504 FPWGRPA 510
Score = 110 bits (274), Expect = 3e-23
Identities = 75/283 (26%), Positives = 148/283 (52%), Gaps = 17/283 (6%)
Query: 420 PDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEE---ERRMEEQ 476
P Q P R G + AD D+ ++R RQ+ ER R++R+ E +R+ E +
Sbjct: 31 PGSQESPRRRG-LGQAHKDADGDD--RERNRQKER-----ERRREKRQTERETDRKRERR 82
Query: 477 RKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRE 536
R+ K R E+ EK+ + RER+R++E+ER ++ E+E+E ERE ER +DR+
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
Query: 537 RQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKE---R 593
++E+E +++ EK+RE + +R+++++ E RQKE+E+E + + +E+E + EKE
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Query: 594 EKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE--- 650
++ E+ RE E E + + + + T ++ + + ETE +
Sbjct: 203 DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER 262
Query: 651 SGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
+ R K+ ++ + QR+ E+ ++ + ++++Q+
Sbjct: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305
Score = 106 bits (265), Expect = 3e-22
Identities = 72/286 (25%), Positives = 149/286 (52%), Gaps = 31/286 (10%)
Query: 434 SKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLG 493
++Q+ + + + R + + ER R+R E+ER + R+ + R E+
Sbjct: 122 NRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER-- 179
Query: 494 ILEKQPSPEEIREREREKE-------------REREKELEKEQEQEREKEREKDRERQQE 540
E++ + +E RERER++E RERE+E E E E ER+++ +++R+RQ++
Sbjct: 180 --EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRK 237
Query: 541 KEKELEKEQEKQREMEKERKQEKEKELE---------RQKEKEKELQKMKEQ--EKECEL 589
E+E EK+ E++R E+E +++KE+E E RQKE+E++ + +++ E++ E
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
Query: 590 EKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEP 649
E++RE+ E+ RE N + E++ + E ++ R K T + E
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
Query: 650 ESGSQPRPAVLSGYFKQFQK---SLPPRFQRQQEQMKQQQWQQQQQ 692
++G + R ++ ++ S R +R++++ + +Q ++++Q
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
Score = 68.6 bits (166), Expect = 9e-11
Identities = 43/164 (26%), Positives = 89/164 (54%), Gaps = 15/164 (9%)
Query: 505 REREREKEREREKELEKEQEQ----EREKEREKDRERQQEK---EKELEKEQEKQREMEK 557
R R +E R + L + + +RE+ R+K+RER++EK E+E ++++E++RE ++
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 558 ERKQEK--EKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQ- 614
RK+++ E++ +R+KE+E++ + +++++E E +++E+ E E + + Q
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 615 --ESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPR 656
E + KE E R+ ++E+ E E E Q R
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQ---KEREREKNRQER 188
Score = 52.0 bits (123), Expect = 8e-06
Identities = 88/470 (18%), Positives = 164/470 (34%), Gaps = 55/470 (11%)
Query: 933 QKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETR 992
QK E+R E + T R D K R +++ +K R + + ++ + R
Sbjct: 59 QKERERRREK-----RQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 993 WGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEK 1052
R R++ +R R G + D + ERE++++ E E+ + + + E+
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 1053 TEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVST 1112
+K+ + + + E E+ E T + + E+ E +
Sbjct: 174 NRQKE--------------REREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 1113 VQVEPAVKTVNQQTMAAPVVKE-EKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYW 1171
+ E +T ++ +E EKQ E+ + + ER +
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDK------------------- 260
Query: 1172 KEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHI 1231
+ RERD D+ R + R R R R R R+ + R+ + E
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Query: 1232 PSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTD----------SEIHESASDKDSL 1281
R+RE R D E +R+R+R +E D + + +
Sbjct: 321 RE---RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
Query: 1282 SKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTR 1341
+ +REER ++ + + R R EK R+ D+ +G
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 1342 RGRG---GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDG 1388
+ +G R+ R G + R + P R + QS+ +P G
Sbjct: 438 KQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRG 487
Score = 47.8 bits (112), Expect = 2e-04
Identities = 88/425 (20%), Positives = 149/425 (35%), Gaps = 31/425 (7%)
Query: 1237 RQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENK 1296
RQRE+ R + + E + R R +TD E E D + + + + +R +
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRE-RERQRDAEKERERQTDRERQRQTER 173
Query: 1297 KPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGE-----PTRRGRGGTFRRG 1351
K K R R EK +D ++ G + E T R R R
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 1352 GRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFER 1411
+ R R A ++ E + D + RR ++ KR + ER
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 1412 KFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNT 1471
+ R+R R++ R +++ +R RERE + + + T
Sbjct: 294 DRETERKRERQRERERERERNR----KRERERERERERERQRETERDREKERERKRKRQT 349
Query: 1472 LGDISGNKTPDLSNQNSSDQANE-EWETASESSDFNERRERDEKKNADLNAQTVVKVGEN 1530
D N+ + +++ E E E +S+ E RERD ++ + + E
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE---RQTEK 406
Query: 1531 VLPPKREIAK-RSFSSQRPVDRQNRRGNNGPPKSGRNFSGPR-NERRSG----------- 1577
+RE K R R +R RG + GR R +R++G
Sbjct: 407 DRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVN 466
Query: 1578 PPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEG---VPNGTGQKNSKDS-TGKKREDPK 1633
PP ++ + G P T S + P G K S+ G++R +P+
Sbjct: 467 PPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPR 526
Query: 1634 PGPKK 1638
G K+
Sbjct: 527 LGEKR 531
Score = 34.7 bits (78), Expect = 1.4
Identities = 51/251 (20%), Positives = 91/251 (36%), Gaps = 17/251 (6%)
Query: 1325 DDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPK 1384
D + +PG + P RRG G + D R R R+ + RQ+E +
Sbjct: 25 DFSRRRPG--SQESPRRRGLGQAHKDADGDDRER-------NRQKERERRREKRQTE--R 73
Query: 1385 PEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLRERE 1444
D + RR E+ KR ER+ D +ER R+ R +++K ++ RERE
Sbjct: 74 ETDRKRERRREKD---RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 1445 AASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSD 1504
+ T+G Q + ++ + + + E + E +
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190
Query: 1505 FNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSG 1564
+RE++ K + + + E + E R + R DRQ + ++
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETETE---RKRQTDRERDRQRKTEREREKQAE 247
Query: 1565 RNFSGPRNERR 1575
R + R R
Sbjct: 248 RERASERETER 258
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 116 bits (290), Expect = 4e-25
Identities = 61/202 (30%), Positives = 121/202 (59%), Gaps = 6/202 (2%)
Query: 446 KQRRRQQSEISAAVERARKRREEEER-RMEEQRKAACAEKLKRLDEKLGILEKQPSPEEI 504
+++R Q S + R+R R+++ R + ++++ E+ K +++ + E+I
Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 384
Query: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564
+E+ER KE++REKE E+E+E+E+EKER K+++R +E+EK+ EK++EK RE E+E++ EK+
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 444
Query: 565 KELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESE----NSC 620
++ E++KE++KE ++ K++ KE + EK ++ + + PR N E S
Sbjct: 445 RDKEKEKEQDKEKEREKDRSKEID-EKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 503
Query: 621 NKEEEPVFTRQDSNRSEKEATP 642
+ P ++ +S + +P
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSP 525
Score = 111 bits (277), Expect = 1e-23
Identities = 79/277 (28%), Positives = 137/277 (49%), Gaps = 23/277 (8%)
Query: 431 PFPSKQQVADE-DEIWKQRRRQQSEISAAVE-RARKRREEEERRMEEQRKAACAEKLKRL 488
P + Q A E +E+ K+ R QS ISAA+E + K E + R ++ K
Sbjct: 264 PEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH 323
Query: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQERE-----------------KER 531
+ K S R R R+K+R R K K++ + RE +E+
Sbjct: 324 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 383
Query: 532 EKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEK 591
K++ER +EK++E E+E+EK+RE EKER + K+++ ER+K++EK+ +K +E+E+E E EK
Sbjct: 384 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 592 EREKLEEKIEPREPNLEPMVEKQ--ESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEP 649
+R+K +EK + +E E K+ E K P + S RS +
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 503
Query: 650 ESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ 686
S PR + ++ +S PR + ++++ ++++
Sbjct: 504 SSSRSPRTS--KTIKRKSSRSPSPRSRNKKDKKREKE 538
Score = 82.0 bits (201), Expect = 7e-15
Identities = 50/209 (23%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
Query: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505
K R + E E+ R++ E E+ E++++ + + EK +K+ E R
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437
Query: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
E+E EK+R++EKE E+++E+EREK+R K+ + +++K+K+ + R +E+
Sbjct: 438 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 497
Query: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
R + + + K +++ +K + RE + + E++E E S + +
Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557
Query: 626 PVFTRQDSNRSEKEATPV---VHETEPES 651
R + EK +T + H EP+S
Sbjct: 558 S-NDRDGKEKLEKNSTSLKEKEHNKEPDS 585
Score = 63.2 bits (152), Expect = 4e-09
Identities = 63/361 (17%), Positives = 159/361 (44%), Gaps = 39/361 (10%)
Query: 294 PSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQ 353
P + + KEL++ EA + + A +E + + ++ +G S S+ +
Sbjct: 264 PEMTPQAAAKELEEVMKRVREA-QSFISAAIEPE-----SGKSNERKGGRSRSHTRSKSR 317
Query: 354 GSKASENNENKKETDEVSNTKSSSQIPAQPSV-AKVPYGKGPSFNQERGTSSHLPPPPKL 412
S S + + ++ S + + S+ + +K P+ K + R + S
Sbjct: 318 SSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS-------- 369
Query: 413 LAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERR 472
+ H R+ + K++V ++D ++ R ++ E + + R +E E+
Sbjct: 370 --RSHSRDKRKDTREK---IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424
Query: 473 MEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQE-------- 524
E+ ++ + ++ EK EK+ ++ +ERE+++ +E +++ +K+++
Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484
Query: 525 ----QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE-LQK 579
+ R RE+ R R + + + +R+ + + ++++EKE++ + +
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 544
Query: 580 MKEQEKECELEKEREKLE--EKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
+E+E+ + K + EK+E +L+ +E ++S +KE + +D+ R+E
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD----KDAPRTE 600
Query: 638 K 638
+
Sbjct: 601 E 601
Score = 57.8 bits (138), Expect = 2e-07
Identities = 76/326 (23%), Positives = 124/326 (38%), Gaps = 36/326 (11%)
Query: 1187 GRGRGEYYSRGRSYRGSYGGRGRG-----GRGHTRDYPQYRDNK-PRAEHIPSGPLRQRE 1240
GR R S+ RS S+ R R R H R + +D + ++ H R+R
Sbjct: 306 GRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERR 365
Query: 1241 ESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVK 1300
+S +RS S D +R+ + + E +K+ + + K +ER +NK K
Sbjct: 366 KSRSRSHSRD------KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK 419
Query: 1301 PHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTF------RRGGRD 1354
+ + + R EK + +D DK K K + + R + R
Sbjct: 420 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 479
Query: 1355 P-----GGRPSRPST--LRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPP 1407
P R SR S+ RR R + +PR S+ K + P P + +K+
Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS------PRSRNKKDK 533
Query: 1408 KFERKFDPARERPRRQRPT--RPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVA 1465
K E++ D ER R+R T R D+ + +L + + K E P + V
Sbjct: 534 KREKERDHISERRERERSTSMRKSSNDRDGK-EKLEKNSTSLKEKEHNKEPDSSVSKEVD 592
Query: 1466 QE--PVNTLGDISGNKTPDLSNQNSS 1489
+ P I N L+ +N S
Sbjct: 593 DKDAPRTEENKIQHNGNCQLNEENLS 618
Score = 52.4 bits (124), Expect = 6e-06
Identities = 49/272 (18%), Positives = 108/272 (39%), Gaps = 20/272 (7%)
Query: 338 DEQGSNSP--KENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPS 395
D + S SP K + S ++ S ++ K D K ++ + + K
Sbjct: 347 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 406
Query: 396 FNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQS-E 454
+ERG + + ++ DR+ + ++ E + K+R + +S E
Sbjct: 407 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
Query: 455 ISAAVERARKRR--------------EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
I ++ +K R ERR R ++ + + + ++ + PS
Sbjct: 467 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS--SRSPS 524
Query: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
P ++++++E+ER+ E+ + + R+ +R +++ E K++E KE
Sbjct: 525 PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 584
Query: 561 QEKEKELERQKEKEKELQKMKEQEKECELEKE 592
KE++ + E K+ + C+L +E
Sbjct: 585 SSVSKEVDDKDAPRTEENKI-QHNGNCQLNEE 615
Score = 51.6 bits (122), Expect = 1e-05
Identities = 59/254 (23%), Positives = 107/254 (42%), Gaps = 42/254 (16%)
Query: 816 EPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLE--------AHPKADFIRESS 867
+P + T A +E E+V Q I+AA E + +H ++ R SS
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKS-RSSS 320
Query: 868 EAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSH 927
++ ++ S+S R H+ + Q D++ +P ++R + E + SR RS S
Sbjct: 321 KSHSRRKRSQSKHRSRSHNRSRSRQK------DRRRSKSPHKKRSKSRERRKSRSRSHSR 374
Query: 928 GSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKS 987
K T I KE ++ + + ++E R E K ++ +
Sbjct: 375 DKR-----------------KDTREKIKEKERVKEKDREKERE---REKEREKEKE--RG 412
Query: 988 KSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVV 1047
K++ R R +++ DR R +K +D +E+E+ ++KE E+ EK K +
Sbjct: 413 KNKDRDKEREKDREKDKEKDRERER----EKEHEKDRDKEKEKEQDKEKER-EKDRSKEI 467
Query: 1048 VKPEKTEKKDLPPP 1061
+ K +KK PP
Sbjct: 468 DEKRKKDKKSRTPP 481
Score = 40.0 bits (92), Expect = 0.033
Identities = 77/401 (19%), Positives = 139/401 (34%), Gaps = 87/401 (21%)
Query: 1241 ESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVK 1300
E ++ + + E V KR R+ S S E S K + KG + R +++ K
Sbjct: 265 EMTPQAAAKELEEVMKRVREAQSFI---SAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 321
Query: 1301 PHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPS 1360
HS K R ++ + + R + K RR ++ + R S
Sbjct: 322 SHSRRK-----RSQSKHRSRSHNRSRSRQKD---------RRRSKSPHKKRSKSRERRKS 367
Query: 1361 RPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERP 1420
R + R +D + ++ E K +D E R E+ ER+ + R +
Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK-------------EREKEKERGKN 414
Query: 1421 RRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKT 1480
+ + R ++K R RERE K +E
Sbjct: 415 KDRDKEREKDREKDKEKDRERERE---KEHE----------------------------- 442
Query: 1481 PDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAK 1540
D + +Q E+ S + +E+R++D+K P ++
Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP--------------PRSYNASR 488
Query: 1541 RSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDL 1600
RS SS R R+ R ++ P++ + R RS P K+ ++
Sbjct: 489 RSRSSSRERRRRRSRSSSRSPRTSKTIK--RKSSRSPSPRSRNKKDKKREKE-------- 538
Query: 1601 INGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKE 1641
+ +E + + +K+S D GK++ + K KE
Sbjct: 539 -RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 578
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 116 bits (290), Expect = 4e-25
Identities = 61/202 (30%), Positives = 121/202 (59%), Gaps = 6/202 (2%)
Query: 446 KQRRRQQSEISAAVERARKRREEEER-RMEEQRKAACAEKLKRLDEKLGILEKQPSPEEI 504
+++R Q S + R+R R+++ R + ++++ E+ K +++ + E+I
Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 268
Query: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564
+E+ER KE++REKE E+E+E+E+EKER K+++R +E+EK+ EK++EK RE E+E++ EK+
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 328
Query: 565 KELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESE----NSC 620
++ E++KE++KE ++ K++ KE + EK ++ + + PR N E S
Sbjct: 329 RDKEKEKEQDKEKEREKDRSKEID-EKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 387
Query: 621 NKEEEPVFTRQDSNRSEKEATP 642
+ P ++ +S + +P
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSP 409
Score = 111 bits (277), Expect = 1e-23
Identities = 79/277 (28%), Positives = 137/277 (49%), Gaps = 23/277 (8%)
Query: 431 PFPSKQQVADE-DEIWKQRRRQQSEISAAVE-RARKRREEEERRMEEQRKAACAEKLKRL 488
P + Q A E +E+ K+ R QS ISAA+E + K E + R ++ K
Sbjct: 148 PEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH 207
Query: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQERE-----------------KER 531
+ K S R R R+K+R R K K++ + RE +E+
Sbjct: 208 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 267
Query: 532 EKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEK 591
K++ER +EK++E E+E+EK+RE EKER + K+++ ER+K++EK+ +K +E+E+E E EK
Sbjct: 268 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 592 EREKLEEKIEPREPNLEPMVEKQ--ESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEP 649
+R+K +EK + +E E K+ E K P + S RS +
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 387
Query: 650 ESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ 686
S PR + ++ +S PR + ++++ ++++
Sbjct: 388 SSSRSPRTS--KTIKRKSSRSPSPRSRNKKDKKREKE 422
Score = 82.0 bits (201), Expect = 7e-15
Identities = 50/209 (23%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
Query: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505
K R + E E+ R++ E E+ E++++ + + EK +K+ E R
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321
Query: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
E+E EK+R++EKE E+++E+EREK+R K+ + +++K+K+ + R +E+
Sbjct: 322 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 381
Query: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
R + + + K +++ +K + RE + + E++E E S + +
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441
Query: 626 PVFTRQDSNRSEKEATPV---VHETEPES 651
R + EK +T + H EP+S
Sbjct: 442 S-NDRDGKEKLEKNSTSLKEKEHNKEPDS 469
Score = 63.2 bits (152), Expect = 4e-09
Identities = 63/361 (17%), Positives = 159/361 (44%), Gaps = 39/361 (10%)
Query: 294 PSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQ 353
P + + KEL++ EA + + A +E + + ++ +G S S+ +
Sbjct: 148 PEMTPQAAAKELEEVMKRVREA-QSFISAAIEPE-----SGKSNERKGGRSRSHTRSKSR 201
Query: 354 GSKASENNENKKETDEVSNTKSSSQIPAQPSV-AKVPYGKGPSFNQERGTSSHLPPPPKL 412
S S + + ++ S + + S+ + +K P+ K + R + S
Sbjct: 202 SSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS-------- 253
Query: 413 LAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERR 472
+ H R+ + K++V ++D ++ R ++ E + + R +E E+
Sbjct: 254 --RSHSRDKRKDTREK---IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308
Query: 473 MEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQE-------- 524
E+ ++ + ++ EK EK+ ++ +ERE+++ +E +++ +K+++
Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368
Query: 525 ----QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE-LQK 579
+ R RE+ R R + + + +R+ + + ++++EKE++ + +
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 428
Query: 580 MKEQEKECELEKEREKLE--EKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
+E+E+ + K + EK+E +L+ +E ++S +KE + +D+ R+E
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD----KDAPRTE 484
Query: 638 K 638
+
Sbjct: 485 E 485
Score = 57.8 bits (138), Expect = 2e-07
Identities = 76/326 (23%), Positives = 124/326 (38%), Gaps = 36/326 (11%)
Query: 1187 GRGRGEYYSRGRSYRGSYGGRGRG-----GRGHTRDYPQYRDNK-PRAEHIPSGPLRQRE 1240
GR R S+ RS S+ R R R H R + +D + ++ H R+R
Sbjct: 190 GRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERR 249
Query: 1241 ESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVK 1300
+S +RS S D +R+ + + E +K+ + + K +ER +NK K
Sbjct: 250 KSRSRSHSRD------KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK 303
Query: 1301 PHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTF------RRGGRD 1354
+ + + R EK + +D DK K K + + R + R
Sbjct: 304 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 363
Query: 1355 P-----GGRPSRPST--LRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPP 1407
P R SR S+ RR R + +PR S+ K + P P + +K+
Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS------PRSRNKKDK 417
Query: 1408 KFERKFDPARERPRRQRPT--RPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVA 1465
K E++ D ER R+R T R D+ + +L + + K E P + V
Sbjct: 418 KREKERDHISERRERERSTSMRKSSNDRDGK-EKLEKNSTSLKEKEHNKEPDSSVSKEVD 476
Query: 1466 QE--PVNTLGDISGNKTPDLSNQNSS 1489
+ P I N L+ +N S
Sbjct: 477 DKDAPRTEENKIQHNGNCQLNEENLS 502
Score = 52.4 bits (124), Expect = 6e-06
Identities = 49/272 (18%), Positives = 108/272 (39%), Gaps = 20/272 (7%)
Query: 338 DEQGSNSP--KENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPS 395
D + S SP K + S ++ S ++ K D K ++ + + K
Sbjct: 231 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 290
Query: 396 FNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQS-E 454
+ERG + + ++ DR+ + ++ E + K+R + +S E
Sbjct: 291 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
Query: 455 ISAAVERARKRR--------------EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
I ++ +K R ERR R ++ + + + ++ + PS
Sbjct: 351 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS--SRSPS 408
Query: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
P ++++++E+ER+ E+ + + R+ +R +++ E K++E KE
Sbjct: 409 PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 468
Query: 561 QEKEKELERQKEKEKELQKMKEQEKECELEKE 592
KE++ + E K+ + C+L +E
Sbjct: 469 SSVSKEVDDKDAPRTEENKI-QHNGNCQLNEE 499
Score = 51.6 bits (122), Expect = 1e-05
Identities = 59/254 (23%), Positives = 107/254 (42%), Gaps = 42/254 (16%)
Query: 816 EPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLE--------AHPKADFIRESS 867
+P + T A +E E+V Q I+AA E + +H ++ R SS
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKS-RSSS 204
Query: 868 EAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSH 927
++ ++ S+S R H+ + Q D++ +P ++R + E + SR RS S
Sbjct: 205 KSHSRRKRSQSKHRSRSHNRSRSRQK------DRRRSKSPHKKRSKSRERRKSRSRSHSR 258
Query: 928 GSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKS 987
K T I KE ++ + + ++E R E K ++ +
Sbjct: 259 DKR-----------------KDTREKIKEKERVKEKDREKERE---REKEREKEKE--RG 296
Query: 988 KSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVV 1047
K++ R R +++ DR R +K +D +E+E+ ++KE E+ EK K +
Sbjct: 297 KNKDRDKEREKDREKDKEKDRERER----EKEHEKDRDKEKEKEQDKEKER-EKDRSKEI 351
Query: 1048 VKPEKTEKKDLPPP 1061
+ K +KK PP
Sbjct: 352 DEKRKKDKKSRTPP 365
Score = 40.0 bits (92), Expect = 0.033
Identities = 77/401 (19%), Positives = 139/401 (34%), Gaps = 87/401 (21%)
Query: 1241 ESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVK 1300
E ++ + + E V KR R+ S S E S K + KG + R +++ K
Sbjct: 149 EMTPQAAAKELEEVMKRVREAQSFI---SAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 205
Query: 1301 PHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPS 1360
HS K R ++ + + R + K RR ++ + R S
Sbjct: 206 SHSRRK-----RSQSKHRSRSHNRSRSRQKD---------RRRSKSPHKKRSKSRERRKS 251
Query: 1361 RPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERP 1420
R + R +D + ++ E K +D E R E+ ER+ + R +
Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK-------------EREKEKERGKN 298
Query: 1421 RRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKT 1480
+ + R ++K R RERE K +E
Sbjct: 299 KDRDKEREKDREKDKEKDRERERE---KEHE----------------------------- 326
Query: 1481 PDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAK 1540
D + +Q E+ S + +E+R++D+K P ++
Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP--------------PRSYNASR 372
Query: 1541 RSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDL 1600
RS SS R R+ R ++ P++ + R RS P K+ ++
Sbjct: 373 RSRSSSRERRRRRSRSSSRSPRTSKTIK--RKSSRSPSPRSRNKKDKKREKE-------- 422
Query: 1601 INGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKE 1641
+ +E + + +K+S D GK++ + K KE
Sbjct: 423 -RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 462
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 115 bits (287), Expect = 8e-25
Identities = 63/207 (30%), Positives = 122/207 (58%), Gaps = 10/207 (4%)
Query: 439 ADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLD-------EK 491
AD D+ ++R R + + +R RKR E R+ +E + EK ++ +K
Sbjct: 72 ADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQK 131
Query: 492 LGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEK 551
E+ E R+R+REKERER+ E +++ ++E E ERE+DRER+++KE+E E+++++
Sbjct: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR 191
Query: 552 QREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMV 611
QR+ EKER+++ ++E +RQ++ + E Q+ ++E E E ++ RE+ ++ +E + E
Sbjct: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE--- 248
Query: 612 EKQESENSCNKEEEPVFTRQDSNRSEK 638
++ E +++E R++ + EK
Sbjct: 249 RDRKEERKKERKKERKKERKEKKKEEK 275
Score = 105 bits (261), Expect = 8e-22
Identities = 58/192 (30%), Positives = 112/192 (58%), Gaps = 3/192 (1%)
Query: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERERE 510
Q+S S + +A K + ++R+ E R EK + D K ++ E R R+RE
Sbjct: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
Query: 511 KEREREKELEKEQEQEREKERE--KDRERQQEKEKELEKEQEKQREMEKERKQEKEKELE 568
K+ E E++ E+E+++ RE+ER+ ++RER +++EKE E++ EK R+ ++E + E+E++ E
Sbjct: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
Query: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVE-KQESENSCNKEEEPV 627
R+K+KE+E ++ ++++++ E E+ER+ E+ R+ E E +E E ++ E
Sbjct: 177 REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ 236
Query: 628 FTRQDSNRSEKE 639
R ++E
Sbjct: 237 RDRDRGKERDRE 248
Score = 102 bits (253), Expect = 7e-21
Identities = 59/214 (27%), Positives = 120/214 (56%), Gaps = 8/214 (3%)
Query: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQS-------EISAAVERARKRREEEERRM 473
DRQ R K++ D ++RR+++ E +ER R+R +++ R
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
Query: 474 EEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK 533
E R R E+ EK + E ERE++REREK+ E+E E++R+++R+
Sbjct: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
Query: 534 DRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER 593
++ER+++ ++E +++++ Q E ++E +E E+E +R++E++++ + KE+++E + ++ER
Sbjct: 196 EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEER 255
Query: 594 EKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627
+K E K E ++ E E++ E+ K E +
Sbjct: 256 KK-ERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
Score = 93.6 bits (231), Expect = 2e-18
Identities = 50/154 (32%), Positives = 97/154 (62%), Gaps = 14/154 (9%)
Query: 505 REREREKERER-EKELEKEQEQEREKERE-------KDRERQQEKEKELEKEQEKQREME 556
R+RER++ RE+ EKE +++++++RE+ R+ +DRE+Q E E++ E+E++K RE E
Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
Query: 557 KERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQES 616
++R +E+E++ +R+KE+E++ +K ++ ++E E E+ER++ EK + RE E+
Sbjct: 137 RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE------TERDRD 190
Query: 617 ENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
++E T ++ +R K T ET+ E
Sbjct: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDRE 224
Score = 90.9 bits (224), Expect = 2e-17
Identities = 43/167 (25%), Positives = 105/167 (62%), Gaps = 4/167 (2%)
Query: 440 DEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQP 499
D + ++ R ++ + ER R R +E ER+ E+ R + +R ++ +K+
Sbjct: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
Query: 500 SPEEIREREREKEREREKELEKEQEQER----EKEREKDRERQQEKEKELEKEQEKQREM 555
E R+R+R+ E+ERE++ ++E++++R E++RE DRE ++E ++ E+++++ R
Sbjct: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK 243
Query: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602
E++R++++++E +++++KE++ ++ +++++E E ++ K E I P
Sbjct: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
Score = 41.6 bits (96), Expect = 0.011
Identities = 45/206 (21%), Positives = 79/206 (38%), Gaps = 14/206 (6%)
Query: 861 DFIRESSEAQVQKFLSRSVEDVRPH-----HTDANNQSACFEAPDQKTLSAPQEERISAV 915
D +RE +E + + R E R + D Q+ +++ + ER
Sbjct: 82 DRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
Query: 916 ESQPSRKRSVSHGSNHTQKPDEQRS-----EPSAGIPKVTSRCIDSKEPIERPEEKPKKE 970
E + R R + D QR E K R + +R EK ++
Sbjct: 142 ERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERER 201
Query: 971 GFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQ 1030
R + + + + + R G R + RRE DR + ++ RD KEER++
Sbjct: 202 QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK----ERDRERDRKEERKK 257
Query: 1031 RKEKEGEKAEKVTEKVVVKPEKTEKK 1056
++KE +K K +K + E ++K
Sbjct: 258 ERKKERKKERKEKKKEEKRREDKKRK 283
Score = 32.7 bits (73), Expect = 5.2
Identities = 44/203 (21%), Positives = 80/203 (39%), Gaps = 15/203 (7%)
Query: 1216 RDYPQYRDNKPRAEHIPSGPLRQREESE--TRSESSDFEVVPKRRRQRGSETDTD---SE 1270
RD + RD + R + + R RE+ R + + +R R RG E + D +
Sbjct: 92 RDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
Query: 1271 IHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAK 1330
E ++KD + + ER ++ K + + + R + E+ R+ D+ +
Sbjct: 152 ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR 211
Query: 1331 PGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEP 1390
T R R T R G R+ R R R RD + R + + ++ +
Sbjct: 212 K------TQTERQR-ETDREGERETDRRRERQRDRDRGKERDRE---RDRKEERKKERKK 261
Query: 1391 PRRHEQFIPIAADKRPPKFERKF 1413
R+ E+ +KR +RK+
Sbjct: 262 ERKKERKEKKKEEKRREDKKRKW 284
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 111 bits (278), Expect = 9e-24
Identities = 238/1139 (20%), Positives = 396/1139 (34%), Gaps = 195/1139 (17%)
Query: 1722 TSKLPPRFAKKQATGIQQAQ------SSASVPPLASAPLPPSTSASVPASTSAP-LPATL 1774
T+ PP + TG + Q +S ++ L+S PS++ + + T P LPATL
Sbjct: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATL 1259
Query: 1775 T---PVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSS 1831
T P +S P P + + P A++ P P A + ++A+ A+T A A T+S
Sbjct: 1260 TSSKPTASSGEPPRPTTAVTP-QATSGLP----PTATLRSTATKPTVTQATTRATASTAS 1314
Query: 1832 SAPAS-APAPTPILASVSTPA----SVTILASASIPILASALASTSAPTPAPAASS-PAA 1885
A S A + T ++ TPA S T+ S + + + T+ P P PA+++ P
Sbjct: 1315 PATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTT 1374
Query: 1886 PVITAPTIPASAPTA--------SVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTH 1937
P PT P + T + P P + +P A +PV P+ P A T
Sbjct: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPV--PSTGPVTATSFHATTT 1432
Query: 1938 KPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLT------AEL 1991
P + +TT LP+ P T S+ TP +H +T A
Sbjct: 1433 YPTPSHPETT------------LPTHVPPFST-------SLVTPSTHTVITPTHAQMATS 1473
Query: 1992 WDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGT 2051
N AP + P P ++ A T+ P++ G S T
Sbjct: 1474 ASNHSAPTGTI------------PPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKT 1521
Query: 2052 DTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKE 2111
T + S+ + EV P + P P R + P A
Sbjct: 1522 PT-SLHSHTSSTHHPEVTPT---STTTITPNPTSTRTRTPVA------------------ 1559
Query: 2112 HKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTM 2171
S + R P TT S + G M
Sbjct: 1560 ----------------------------HTNSATSSRPPPPFTTHSPPTGSSPFSSTGPM 1591
Query: 2172 ISVSSAEYGTNAKESVTDYTTPS---SSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRE 2228
+ S ++ T Y TPS ++LP V +T + + V P +
Sbjct: 1592 TATSF--------KTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA 1643
Query: 2229 TIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGP 2288
+I + T PPTT T +A + + S + + +T + S S
Sbjct: 1644 SIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTA--KTSTSLHSHTSST 1701
Query: 2289 STANYNSFSSASMPQIPVASVTPTASLSGAGT-YTTSSLSTKSTTTSDPPNICKVKPQQL 2347
A S S+ ++ P ++ TP +++ +GT + SS ST T+TS
Sbjct: 1702 HHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTS--------LHSHT 1753
Query: 2348 QTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAP 2407
++ P + S S P+ + + P + + + ++++P + T+H T ++
Sbjct: 1754 SSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPF--TTHSPPTGTTPISS 1811
Query: 2408 PSLAQQQGFQPGLSQPT-SVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQP 2466
FQ + PT S +P + P S + Q S+S+
Sbjct: 1812 TGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASI-- 1869
Query: 2467 YRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQ--QTSNTQPIPILYE 2524
S P ++ P+ + + + H P + +QS +F +TS + P
Sbjct: 1870 -HSMPT---GTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSST 1925
Query: 2525 HQLGQASGLGGSQLIDTHL-LQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVT 2583
H + + + + H R + ++ S ++ P T+ T SP + T
Sbjct: 1926 HH-PEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFS---ST 1981
Query: 2584 VPLPASQL-SLPNFGSTGQPLIALPQTLQP-------PLQHTTPQAQAQSLSRPAQVSQP 2635
P+ A+ + + + P LP + P P HT ++ A +
Sbjct: 1982 GPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHST 2041
Query: 2636 FRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRS--------TTPTSSP 2687
G +P T LKA GS P T +G S T +SS
Sbjct: 2042 PTGTVPPPT--------------TLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSF 2087
Query: 2688 FRATSTSPNSQSSKMNSIVYQKQ---FQSAPATVRMTQPFPTQFAPQAKQRAEVLQSTQR 2744
++S P + SS+ S Q SA V T + F+P + V
Sbjct: 2088 ISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPS 2147
Query: 2745 FFSEQQQSKQIGGGKAQKVDSD------SSKPPETLTDPPGVCQEKVEEKPPPAPSIAT 2797
S Q S G + V + SS +L+ P P +P+ +T
Sbjct: 2148 SHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAAST 2206
Score = 68.6 bits (166), Expect = 9e-11
Identities = 119/523 (22%), Positives = 192/523 (36%), Gaps = 70/523 (13%)
Query: 1722 TSKLPPRFAKKQATGIQQAQSSASVPPLA-----SAPLPPS-----TSASVPASTSAPLP 1771
T +PP T I+ S+ + PP+ ++ P S TS S+P TS+
Sbjct: 1874 TGTIPP------PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHH 1927
Query: 1772 ATLTPVPASTSAPVPAST--LAPVLASTSA-----PVPASPLAPVSASASVSASVPASTS 1824
+TP + P ST PV +TSA P P + +P + S+ S++ P + +
Sbjct: 1928 PEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTAT 1987
Query: 1825 AAAITSSSAPASAPAPT------PILASVSTPASVTILASASIPILASA-LASTSAPTPA 1877
+ T++ S P T P S+ TP++ T++ + + SA + ST T
Sbjct: 1988 SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVP 2047
Query: 1878 P------AASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAP-TPVSAPNPAPPAPA 1930
P S+ AP +T T S +S A AS+S + + P ++ + P +P
Sbjct: 2048 PPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPI 2107
Query: 1931 QTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAE 1990
TQ P+ TT+Q S PS PS + YV S S S T+
Sbjct: 2108 TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV----SSYVPSSHSSPQTSSPSVGTSS 2163
Query: 1991 LWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIG 2050
+ V+ P +S P + S PL F S+P++
Sbjct: 2164 SF---VSAPVHSTTLSSGSHSSLSTHPTTASVSASPL--FPSSPAA-------------- 2204
Query: 2051 TDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENK 2110
+ TI+ P + + + +L + P P A P +P
Sbjct: 2205 STTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFP--------STPRTTA 2256
Query: 2111 EHKPGPIGKERSLKNRKVKDAQQVEPEG-QEKPSPATVRSTDPVTTKETKAVSEMSTEIG 2169
P +S +R +V G S T T PVT T+ +
Sbjct: 2257 STHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTT 2316
Query: 2170 TMISVSSAEYG-TNAKESVTDYTTPSSSLPNTVATNNTKMEDT 2211
++ S +G T A V+ TP+ + P + + E T
Sbjct: 2317 RFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVREQQEEIT 2359
Score = 59.7 bits (143), Expect = 4e-08
Identities = 76/266 (28%), Positives = 119/266 (44%), Gaps = 43/266 (16%)
Query: 1709 WNKKNANEKGRSQ--TSKLPP-RFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAS 1765
W +N++ + S T++LP A + Q SS S P A P + S+ VP+S
Sbjct: 2093 WLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSA----PSTVSSYVPSS 2148
Query: 1766 TSAPLPATLTPVPAST--SAPVPASTLAPVLAS------TSAPVPASPLAPVS--ASASV 1815
S+P ++ + +S+ SAPV ++TL+ S T+A V ASPL P S AS ++
Sbjct: 2149 HSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208
Query: 1816 SASVPASTSAAAITSSSAPAS----APAPTPILAS--VSTPASVTILASA-SIPILAS-- 1866
A++P + S+ S+ P S +P P+ LAS ++ P++ AS + P +S
Sbjct: 2209 RATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQS 2268
Query: 1867 -ALASTSAPTPAPAA-------------SSPAAPVITAPTIPASAPTASVPLAPASASAP 1912
STS T P + +SP + T P +PT + +A
Sbjct: 2269 TTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGS 2328
Query: 1913 APAPTPVSA---PNPAPPAPAQTQAQ 1935
PA PVS+ P P P + Q
Sbjct: 2329 TPASAPVSSLGTPTPTSPGVCSVREQ 2354
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 110 bits (276), Expect = 2e-23
Identities = 55/190 (28%), Positives = 109/190 (57%), Gaps = 9/190 (4%)
Query: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505
K R + ++R R+RR E +R + +++ ++ D + + R
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR---------DRER 54
Query: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
RER+++REREK+ ++E E++RE+ER++DR+R+ E+E++ E+E ++ E ++ER+++KE+
Sbjct: 55 NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER 114
Query: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
E+ER +++E+E QK +E++ + E +RE+ + RE E E + E ++ E
Sbjct: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
Query: 626 PVFTRQDSNR 635
R+ R
Sbjct: 175 RERKRETKER 184
Score = 106 bits (264), Expect = 4e-22
Identities = 62/205 (30%), Positives = 120/205 (58%), Gaps = 12/205 (5%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
E E ++R ++ E +RA++ + E+ ++++ + + D + EKQ
Sbjct: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER---EKQTD 69
Query: 501 PEEIREREREKEREREKELEKEQEQEREKER--EKDRERQQEKEKELE----KEQEKQRE 554
E R+RERE++R+R++E E+E+++ERE +R E DRERQ++KE+E+E +E+EKQ+E
Sbjct: 70 REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
Query: 555 MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQ 614
M +ER+ ++E + ER+++ E+E + +E++ E ++ RE+ E+ RE E ++
Sbjct: 130 MGRERQTDRETDRERERQAERERETGRERKTE---DRHRERERERKRERERKRETKERER 186
Query: 615 ESENSCNKEEEPVFTRQDSNRSEKE 639
++ ++ E R SE+E
Sbjct: 187 HTDMERERQRETDRKRDRQRESERE 211
Score = 91.3 bits (225), Expect = 1e-17
Identities = 52/159 (32%), Positives = 100/159 (62%), Gaps = 8/159 (5%)
Query: 440 DEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQP 499
D D +++ ++ E ER R R+ E ER +++R+ + R +K +K+
Sbjct: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQK----QKER 114
Query: 500 SPEEIREREREKERE--REKELEKEQEQEREKEREKDRERQQE-KEKELEKEQEKQREME 556
E +R+REREK++E RE++ ++E ++ERE++ E++RE +E K ++ +E+E++R+ E
Sbjct: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
Query: 557 KERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREK 595
+ERK+E KE ER + E+E Q+ +++++ + E ERE+
Sbjct: 175 RERKRE-TKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 87.0 bits (214), Expect = 2e-16
Identities = 53/196 (27%), Positives = 112/196 (57%), Gaps = 11/196 (5%)
Query: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQE--KEKELEKEQEKQREMEKERKQE 562
R+RER +E +RE++ KE + E ++ E+DR+R +E +E++ ++E+EKQ + E ER++E
Sbjct: 19 RQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
Query: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREKLE----EKIEPRE-PNLEPMVEKQESE 617
+E++ +RQ+E E+E K +E ++ E ++ER+K + E++ RE + M +++++
Sbjct: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
Query: 618 NSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQR 677
++E E R+ E++ E E E + R K+ ++ +R
Sbjct: 138 RETDRERERQAERERETGRERKTEDRHRERERE---RKRERERKRETKERERHTDMERER 194
Query: 678 QQEQMKQQQWQQQQQQ 693
Q+E +++ Q++ ++
Sbjct: 195 QRETDRKRDRQRESER 210
Score = 83.2 bits (204), Expect = 3e-15
Identities = 51/162 (31%), Positives = 95/162 (58%), Gaps = 7/162 (4%)
Query: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRME--EQRK 478
DR+ R ++Q E E ++R R + ER R + E +R E +R+
Sbjct: 51 DRERNRERDRDREREKQTDREGERQRERERDRDR-QRETERERDKERETDRHTETDRERQ 109
Query: 479 AACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKE---REKDR 535
+++R+ ++ +K+ E +RE ++ERER+ E E+E +ER+ E RE++R
Sbjct: 110 KQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERER 169
Query: 536 ERQQEKEKELE-KEQEKQREMEKERKQEKEKELERQKEKEKE 576
ER++E+E++ E KE+E+ +ME+ER++E +++ +RQ+E E+E
Sbjct: 170 ERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
Score = 65.1 bits (157), Expect = 9e-10
Identities = 39/184 (21%), Positives = 96/184 (52%), Gaps = 5/184 (2%)
Query: 511 KEREREKELEKE-QEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
K R E E +++RE+ RE DRER + KE + E ++ +R+ +++R++ +E++ +R
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDR 62
Query: 570 QKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFT 629
++EK+ + + +++E+E + +++RE E+ + RE + +++ + KE E
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQK---QKEREMERV 119
Query: 630 RQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ 689
R +KE + R A + +K+ +R++E+ ++++ ++
Sbjct: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
Query: 690 QQQQ 693
+ ++
Sbjct: 180 ETKE 183
Score = 63.2 bits (152), Expect = 4e-09
Identities = 34/110 (30%), Positives = 68/110 (61%), Gaps = 6/110 (5%)
Query: 449 RRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE---EIR 505
R +Q + +ER R R E+++ M +R+ + R E+ E++ E E R
Sbjct: 106 RERQKQKEREMERVRDREREKQKEMGRERQTD--RETDRERERQAERERETGRERKTEDR 163
Query: 506 EREREKEREREKELEKE-QEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
RERE+ER+RE+E ++E +E+ER + E++R+R+ +++++ ++E E++R+
Sbjct: 164 HRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 51.2 bits (121), Expect = 1e-05
Identities = 32/108 (29%), Positives = 59/108 (54%), Gaps = 10/108 (9%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
KQ+ + + + + R +Q E+ + R+ E ER+ E +R+ K +
Sbjct: 110 KQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR---- 165
Query: 495 LEKQPSPEEIRERERE-KEREREKELEKEQEQE----REKEREKDRER 537
E++ + RER+RE KERER ++E+E+++E R+++RE +RER
Sbjct: 166 -ERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 47.8 bits (112), Expect = 2e-04
Identities = 23/97 (23%), Positives = 52/97 (53%)
Query: 436 QQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIL 495
++V D + ++ ++ + +R R+R+ E ER +RK + + + K
Sbjct: 117 ERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERE 176
Query: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKERE 532
K+ + E R + E+ER+RE + ++++++E E+ER+
Sbjct: 177 RKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 33.5 bits (75), Expect = 3.0
Identities = 43/181 (23%), Positives = 67/181 (37%), Gaps = 31/181 (17%)
Query: 1373 NQWNPRQSEVPKPEDGEPPRRHEQFIPIAADK-RPPKFERKFDPARERPRRQRPTRPPRQ 1431
N+ R E K D E R+ E+ D+ R + ER+ D RE R R ++
Sbjct: 55 NRERDRDREREKQTDREGERQRER----ERDRDRQRETERERDKERETDRHTETDRERQK 110
Query: 1432 DKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQ 1491
K R+R+RE +E +G +T +++ Q
Sbjct: 111 QKEREMERVRDRE---------------------REKQKEMG--RERQTDRETDRERERQ 147
Query: 1492 ANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDR 1551
A E ET E + RER+ ++ + + K E +RE R + R DR
Sbjct: 148 AERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERE---RQRETDRKRDR 204
Query: 1552 Q 1552
Q
Sbjct: 205 Q 205
Score = 33.1 bits (74), Expect = 4.0
Identities = 33/177 (18%), Positives = 66/177 (37%), Gaps = 32/177 (18%)
Query: 338 DEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFN 397
D +G + D+ + + ++ETD + T Q + + +V +
Sbjct: 69 DREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR-------D 121
Query: 398 QERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISA 457
+ER + R+ R ++Q E E ++R+ +
Sbjct: 122 REREKQKEM--------------GRERQTDRETDRERERQAERERETGRERKTED----- 162
Query: 458 AVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERE 514
R R E ER+ E +RK E+ + D + +++ + R+RE E+ER+
Sbjct: 163 -----RHRERERERKRERERKRETKERERHTDMERE-RQRETDRKRDRQRESERERD 213
Score = 32.3 bits (72), Expect = 6.8
Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 12/136 (8%)
Query: 910 ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKK 969
ER + + R+R + ++ + +R + + T R ++ ER ++K ++
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKE-----RETDRHTETDR--ERQKQKERE 115
Query: 970 EGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEERE 1029
+R E K +++ + + R ++R E R +G +K R + ERE
Sbjct: 116 MERVRDREREKQKEMGRERQTDR-----ETDRERERQAERERETGRERKTEDRHRERERE 170
Query: 1030 QRKEKEGEKAEKVTEK 1045
+++E+E ++ K E+
Sbjct: 171 RKRERERKRETKERER 186
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 108 bits (271), Expect = 6e-23
Identities = 74/264 (28%), Positives = 151/264 (57%), Gaps = 16/264 (6%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
++++ +++EIW+Q+ + + E+ RK+ E+ R+ E+ R+ EK++ +EK+
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQ----EEKIRKQEEKVWRQEEKIREQE--EKIREQEEKMWR 535
Query: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
E++ +E RE EK E+EK E+E+ QE+E + + E+ +E+E+++ +++EK RE
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 555 MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQ 614
E E++QE+E+++ +Q+EK +E Q+ K QE+E ++ ++ EK+ E+ E + E M E++
Sbjct: 596 QE-EKRQEQEEKMWKQEEKIRE-QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
Query: 615 E---SENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQK-- 669
E + +E+E RQ+ E+E E + + ++Q +K
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713
Query: 670 SLPPRFQRQQEQMKQQQ---WQQQ 690
+ Q Q+E+M++Q+ W+Q+
Sbjct: 714 EQEEKMQEQEEKMRRQEEKMWEQE 737
Score = 102 bits (253), Expect = 7e-21
Identities = 74/278 (26%), Positives = 153/278 (55%), Gaps = 39/278 (14%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
E+ +W++ + + + E+ K R +EE E++ EK++R +E + EK+
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE------EKMRRQEEMMW--EKEEK 392
Query: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
E+ E+ E+E+ RE+E ++++E E+ +++E++QE+E ++ +++EK RE E E+
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEE-----EKIREQEKRQEQEAKMWRQEEKIREQE-EKI 446
Query: 561 QEKEKELERQKEKEKELQKMKEQEKECELE----------------KEREKL---EEKIE 601
+E+EK++ RQ+EK E +K++E+EK E E +++EK+ EEKI
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 602 PREPNLEPMVEK-QESENSCNKEEEPVFTRQDSNRSEKE---ATPVVHETEPESGSQPRP 657
+E + EK +E E ++EE ++ +++ R ++E +HE E + R
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 658 AVLSGYFKQFQK--SLPPRFQRQQEQMKQQQWQQQQQQ 693
++Q +K + RQ+E++++Q+ ++Q+Q+
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE 604
Score = 96.7 bits (239), Expect = 3e-19
Identities = 79/278 (28%), Positives = 152/278 (54%), Gaps = 29/278 (10%)
Query: 441 EDEIWKQRR--RQQSEISAAVERARKRREE---EERRMEEQRKAACAEKLKRLDEKLGIL 495
E ++W+Q R+Q E E+ R+EE E+ ++ E+ K E++ R +EK+
Sbjct: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
Query: 496 EKQPSPEEIREREREKERE------REKELEKEQEQEREKEREKDRERQQEK---EKELE 546
E+ +E + EK R+ R++E +EQE E+ +E+E+ RQ+EK ++E+
Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE-EKIREQEEKMWRQEEKIREQEEMW 547
Query: 547 KEQEKQREMEK----ERKQEKEKELERQKEK--EKELQKMKEQEKECELEKEREKLEEKI 600
+E+EK E EK E++QE+E ++ RQ+EK E+E + +++EK E E++R++ EEK+
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Query: 601 EPREPNLEPMVEK-QESENSCNKEEEPVFTRQDSNRSEKEATPVVHE--TEPESGSQPRP 657
+E + EK QE E ++EE + +++ + ++E E E E Q +
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 658 AVLSGYFKQFQK--SLPPRFQRQQEQMKQQQWQQQQQQ 693
+ ++Q +K + + Q+E++++Q+ Q+Q+
Sbjct: 668 ETM---WRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702
Score = 96.3 bits (238), Expect = 4e-19
Identities = 70/267 (26%), Positives = 149/267 (55%), Gaps = 11/267 (4%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
++++ ++E+ ++ + E+ + K RE+EE+R EE+ K EK + + K+
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE-KIREQEKRQEQEAKMWR 434
Query: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
E++ +E + RE+EK+ R++E EQE+ RE+E+ +++E +E+++ +++E R
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR- 493
Query: 555 MEKERKQEKEKELERQKEKE-KELQKMKEQEKEC-ELEKEREKLEEKIEPREP--NLEPM 610
+KE+ E+E+++ +Q+EK ++ +K++EQE++ E E++ + EEKI +E E
Sbjct: 494 -QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 611 VEKQES--ENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQ 668
+ +QE E +E+E RQ+ E+E E + + R +KQ +
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 669 K--SLPPRFQRQQEQMKQQQWQQQQQQ 693
K + Q Q+E++++Q+ + ++Q+
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQE 639
Score = 94.0 bits (232), Expect = 2e-18
Identities = 61/185 (32%), Positives = 115/185 (62%), Gaps = 15/185 (8%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEE-RRMEEQRKAACAEKLKRLDEKLGILEKQP 499
ED++W+Q + + + + K RE+EE R+ +E++ EK++ +EK+ Q
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI-----QE 623
Query: 500 SPEEIREREREKEREREKELEKEQEQEREKEREK---DRERQQEKEKELEKEQEKQREME 556
E+IRE+E EK RE+E E+ +EQE++ ++ EK E+ QE+E+ + +++EK RE E
Sbjct: 624 QEEKIREQE-EKIREQE-EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
Query: 557 KERKQEKEKELERQKEKEKELQKMKEQ-EKECELEKEREKLEEKIEPREPNL---EPMVE 612
K+ ++++EK E+++ +++ +KM EQ EK CE E++ ++ EEK+ +E + E +
Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
Query: 613 KQESE 617
+QE +
Sbjct: 742 QQEEK 746
Score = 93.6 bits (231), Expect = 2e-18
Identities = 62/212 (29%), Positives = 129/212 (60%), Gaps = 10/212 (4%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
++++ +++E+W++ + + E R+ +E++ R EE+ + EK+ R +EK+
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ-EEKVWRQEEKIRE 595
Query: 495 LE-KQPSPEEIREREREKEREREKELEKEQEQEREKE---REKDRERQQEKEKELEKEQE 550
E K+ EE ++ EK RE+E+++++++E+ RE+E RE++ Q+++EK + +++E
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK-MGEQEE 654
Query: 551 KQREMEKERKQEKEKELERQKEKEKELQK--MKEQEKECELEKEREKLEEKIEPREPNLE 608
K E E E+ QE+E+ + RQ+EK +E +K +++EK E E+ ++ EEK+ +E +
Sbjct: 655 KMCEQE-EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713
Query: 609 PMVEK-QESENSCNKEEEPVFTRQDSNRSEKE 639
EK QE E ++EE ++ ++ R ++E
Sbjct: 714 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Score = 89.4 bits (220), Expect = 5e-17
Identities = 72/279 (25%), Positives = 153/279 (54%), Gaps = 43/279 (15%)
Query: 436 QQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIL 495
Q +E+E+W + +QQ E + R ++ +E E +++EQ EK++ +EK+
Sbjct: 282 QAQVEENELWNRLNQQQEE---KMWRQEEKIQEWEEKIQEQE-----EKIREQEEKIREQ 333
Query: 496 EKQPSPEEIREREREKEREREKEL--EKEQEQEREKE----REKDRERQQE----KEKEL 545
E++ +E E+E++ R++E+ EKE++ R++E +E+ RQ+E KE+++
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
Query: 546 EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER-EKLEEKIEPRE 604
+ +EK E EK R+QE++++ ++EK +E +K +EQE + ++E+ + EEKI +E
Sbjct: 394 RELEEKMHEQEKIREQEEKRQ---EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
Query: 605 PNL---EPMVEKQES--ENSCNKEEEPVFTRQDSNRSEKE---ATPVVHETEPESGSQPR 656
+ E + +QE E +E+E ++ +++ ++E +HE E + Q
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 657 PAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ---WQQQQQ 692
++Q +K + Q+E++++Q+ W+Q+++
Sbjct: 511 KV-----WRQEEK-----IREQEEKIREQEEKMWRQEEK 539
Score = 82.8 bits (203), Expect = 4e-15
Identities = 65/250 (26%), Positives = 128/250 (51%), Gaps = 9/250 (3%)
Query: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKL-KRLDEKLGILEKQPSPEEIRERER 509
++SEI V+ +++ E + + +Q+ A A+ L K L L+ Q E+ R
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 510 EKERE---REKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM--EKERKQEKE 564
+++ E R++E +E E++ +++ EK RE Q+EK +E E++ +Q EM EKE K ++
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 565 KELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEE 624
+E+ +KE++ Q+ EKE ++ ++ E + EK E E M E+++ K +
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 414
Query: 625 EPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQ 684
E R+ R E+EA E + + ++Q +K R++E+ ++
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 685 QQ--WQQQQQ 692
Q+ W+Q+++
Sbjct: 475 QEEMWRQEEK 484
Score = 81.6 bits (200), Expect = 1e-14
Identities = 53/160 (33%), Positives = 94/160 (58%), Gaps = 16/160 (10%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEER-RMEEQRKAACAEKLKRLDEKL-GILEKQ 498
E+++WKQ + + + E+ K RE+EE+ R +E+ EK+ +EK+ EK
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 663
Query: 499 PSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKE 558
EE R+ EK RE+EK++ +++E+ RE+E E QE+E+++ +++EK E E E
Sbjct: 664 QEQEETMWRQEEKIREQEKKIREQEEKIREQE-----EMMQEQEEKMWEQEEKMCEQE-E 717
Query: 559 RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEE 598
+ QE+E+++ RQ+E K E+E L ++ EK++E
Sbjct: 718 KMQEQEEKMRRQEE--------KMWEQEVRLRQQEEKMQE 749
Score = 73.6 bits (179), Expect = 3e-12
Identities = 71/290 (24%), Positives = 141/290 (48%), Gaps = 51/290 (17%)
Query: 445 WKQRRRQQSEISAAVERARKR--------REEEERRMEEQRKAACAEKLK----RLDEKL 492
WK + +SA + +K +E + +E R E+LK +L EKL
Sbjct: 171 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKL 230
Query: 493 GILEKQPSPEEIREREREKEREREKELEKEQEQERE-------------------KEREK 533
++E + S ++ +E +++ ER K L +Q+ + E +E E
Sbjct: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 290
Query: 534 DRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQ-KMKEQE-----KEC 587
Q++E+++ +++EK +E E E+ QE+E+++ Q+EK +E + KM+ QE KE
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWE-EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
Query: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHE- 646
++ ++ E + EK E E M EK+E ++EE ++ +++ R +E +HE
Sbjct: 350 KMRRQEEMMWEKEEKMRRQEEMMWEKEEK---MRRQEEMMWEKEEKIRELEEK---MHEQ 403
Query: 647 ---TEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
E E Q + +Q Q++ + RQ+E++++Q+ + ++Q+
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKIREQE 450
Score = 48.1 bits (113), Expect = 1e-04
Identities = 133/735 (18%), Positives = 268/735 (36%), Gaps = 107/735 (14%)
Query: 402 TSSHLPPPPKLLAQQHPP-----PDRQAVPGRPGPFPSKQQ---VADEDEIWKQRRRQQS 453
T HLP P L H P P +P P +Q ++++ +
Sbjct: 17 THPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNP 76
Query: 454 EISAAVERARKRR-----------------EEEERRMEEQRKAACAEKLKRLDEKLGILE 496
+ A +K++ E+E++ Q + A +L+ + IL
Sbjct: 77 SVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILT 136
Query: 497 KQP---------SPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKE----- 542
Q S +++ E E R+ L + E E+ Q+K+
Sbjct: 137 CQKTELQMALYYSQHAVKQLEGEA-RDLISRLHDSWKFAGELEQALSAVATQKKKADRYI 195
Query: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602
+EL KE++ +E R ++EL+ + K +E ++ E EK E++ ++L+ K+E
Sbjct: 196 EELTKERDAL-SLELYRNTITDEELKEKNAKLQEKLQLVESEKS-EIQLNVKELKRKLE- 252
Query: 603 REPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSG 662
R L P + Q + KE + V + + E E +++ + E + +
Sbjct: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI--- 309
Query: 663 YFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQ 722
+ + Q Q+E++++Q+ + ++Q+ + + +++ +
Sbjct: 310 ------QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 723 PHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNS 782
+ M W + M I + M + + R+Q E
Sbjct: 364 KMRRQEEMM-----WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI--REQEEKRQEE 416
Query: 783 SESFEHIARSARDHAISLSEPRM-------------LWGSDPYPHAEPQQATTPKATEEP 829
+ E R ++ + E ++ +W + H + + K E+
Sbjct: 417 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
Query: 830 EDVRSEAAL-DQEQITAAYSVEHNQLEAHPKADF--------IRESSEA--QVQKFLSRS 878
E R E + +QE+I H Q E K + IRE E + ++ + R
Sbjct: 477 EMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
Query: 879 VEDVRPHHTDANNQSACFEAP---------DQKTLSAPQEERISAVESQPSRKRSVSHGS 929
E +R + E +Q+ QEE+I E + R+
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE----- 591
Query: 930 NHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKK-EGFIRSSEGPKPEKVYKS- 987
++ +E+R E + K + + +E I+ EEK ++ E IR E E+ K
Sbjct: 592 -KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 988 -------KSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAE 1040
+ E + + + R+E R + ++ +R+ +E ++++EK E+ E
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 1041 KVTEKVVVKPEKTEK 1055
K+ E+ E+ EK
Sbjct: 711 KMCEQEEKMQEQEEK 725
Score = 47.8 bits (112), Expect = 2e-04
Identities = 34/143 (23%), Positives = 77/143 (53%), Gaps = 34/143 (23%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAV-ERARKRREEEE------RRMEEQRKAACAEKLKR 487
++++ +++E+ +++ + E + E+ K +E+EE ++ EQ K
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK--------- 682
Query: 488 LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQ--EREKEREKDRERQQEKEKEL 545
+IRE+E EK RE+E+ +++++E+ E+E++ + E+ QE+E+++
Sbjct: 683 ---------------KIREQE-EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 726
Query: 546 EKEQEKQREMEKERKQEKEKELE 568
+++EK E E +Q++EK E
Sbjct: 727 RRQEEKMWEQEVRLRQQEEKMQE 749
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 108 bits (270), Expect = 7e-23
Identities = 55/194 (28%), Positives = 118/194 (60%), Gaps = 7/194 (3%)
Query: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI-LEKQPSPEEI 504
++ R+++++ ER R R+ E E + E + + ++ + D + E++ E
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Query: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564
R+R+RE+E ERE E ++E++++RE++R+ DRER +++++E ++E ++ RE ++ +E++
Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
Query: 565 KELERQKEKEKELQKMKEQEKECELEKEREKLEEK---IEPREPNLEPMVEKQESENSCN 621
K+ ER++++E+E Q+ +E+E++ + E++RE E+ E E E E+++
Sbjct: 124 KQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK 183
Query: 622 KEEEPVFTRQDSNR 635
KEE+ R+D R
Sbjct: 184 KEEK---RREDKKR 194
Score = 100 bits (249), Expect = 2e-20
Identities = 48/187 (25%), Positives = 115/187 (61%), Gaps = 4/187 (2%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
E E +QR R+ R R R E +R+ + +++ ++ R ++ E++
Sbjct: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQR----ERETE 73
Query: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
E R+RER+++RER+++ ++E++++R++ER+++ +R +E+ ++ +E++KQ E E++R+
Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133
Query: 561 QEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSC 620
+E++++ ER++++++E ++ ++E++ E+E K E K E ++ E E++ E+
Sbjct: 134 RERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
Query: 621 NKEEEPV 627
K E +
Sbjct: 194 RKWGEGI 200
Score = 99.4 bits (246), Expect = 5e-20
Identities = 48/188 (25%), Positives = 114/188 (60%), Gaps = 9/188 (4%)
Query: 459 VERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKE 518
+ER R+R+ E +R E +R+ + + E+ +Q R+R+ ++E+ERE++
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERDRQTDREKERERQ 59
Query: 519 LEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQ-------- 570
E++++++RE+E E++ ERQ+E++++ E++++ RE +K+R +E+++E +R
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 571 KEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTR 630
+E++K+ ++ +++E+E + ++ERE+ ++ RE + E + E +++E R
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 631 QDSNRSEK 638
++ + EK
Sbjct: 180 KEKKKEEK 187
Score = 98.2 bits (243), Expect = 1e-19
Identities = 50/170 (29%), Positives = 104/170 (61%), Gaps = 2/170 (1%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
E E + R+R++ + R R+R ER + R+ + +R ++ E +
Sbjct: 16 ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE 75
Query: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKE--KELEKEQEKQREMEKE 558
E RER+R++ER+R+ + E++++++RE++RE DR R++ ++ +E +K+ E++R+ E+E
Sbjct: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
Query: 559 RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLE 608
R++++E+E +RQ+E+++E + +++ E E K+ K E K E +E E
Sbjct: 136 RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKE 185
Score = 92.8 bits (229), Expect = 4e-18
Identities = 47/158 (29%), Positives = 102/158 (64%), Gaps = 10/158 (6%)
Query: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505
K+R RQ+ +R R+R E ER E QR+ + KR ++ E+ + R
Sbjct: 54 KERERQKER-----DRQRQRERETERETERQRERQRQRERKRQTDR----ERDKDRDRER 104
Query: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
+RE ++ RER ++ +E++++ E+ER+++RERQ+++E+E ++++E++RE ++ER++ E+
Sbjct: 105 KRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
Query: 566 E-LERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602
E +++++KE++ ++ +++++E E ++ K E I P
Sbjct: 165 EERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
Score = 74.3 bits (181), Expect = 2e-12
Identities = 43/176 (24%), Positives = 95/176 (53%), Gaps = 16/176 (9%)
Query: 524 EQEREKEREKDRERQQEKEKELEKEQEKQREME-KERKQEKEKELERQKEKEKELQKMKE 582
E++RE++RE DR ++ E+E++ ++E+E Q E E + R++++ +E +RQ ++EKE ++ KE
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 583 QEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATP 642
++++ + E+E E+ E+ R+ E + + E T ++ R+ K
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
Query: 643 VVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQ-----QQWQQQQQQ 693
+TE E + ++ Q+ QRQ+E+ ++ Q+W +++++
Sbjct: 122 RDKQTERERDRE----------RERQRQRERERQRQRERKRETDRERQRWAEREER 167
Score = 42.0 bits (97), Expect = 0.009
Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 26/113 (23%)
Query: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA 480
DR R G +Q E + ++R+RQ+ ER R+R+ E +R + +R
Sbjct: 109 DRNRERNRKGGRERDKQTERERDRERERQRQR-------ERERQRQRERKRETDRER--- 158
Query: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK 533
++ + E R++ER+KER++E++ +K++E+ RE ++ K
Sbjct: 159 ----------------QRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 37.0 bits (84), Expect = 0.28
Identities = 31/163 (19%), Positives = 64/163 (39%), Gaps = 9/163 (5%)
Query: 883 RPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEP 942
R H + + Q+ + +++ Q +R E + R+R ++ D +R +
Sbjct: 40 RDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK- 98
Query: 943 SAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRR 1002
R + K +R E+ +K G R + + + + R R R
Sbjct: 99 --------DRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRER 150
Query: 1003 EEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEK 1045
+ DR +R ++ KE +++RKEK+ E+ + +K
Sbjct: 151 KRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
Score = 36.6 bits (83), Expect = 0.36
Identities = 38/199 (19%), Positives = 83/199 (41%), Gaps = 11/199 (5%)
Query: 1237 RQREESETRSESSDFEVVPKRRRQRGSETDTDS--EIHESASDKDSLSKGKLPKREERPE 1294
RQRE + E R+R+R ++T+ ++ + ++D + + + ++
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 1295 NKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRD 1354
+++ + + + R R E+ D ++ K + T R R R+GGR+
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN-RKGGRE 121
Query: 1355 PGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFD 1414
+ R R R + R+ + + E R +++ A++ K ERK +
Sbjct: 122 RDKQTERERDRERERQRQRE---RERQRQRERKRETDRERQRW----AEREERKKERKKE 174
Query: 1415 PARERPRRQRPTRPPRQDK 1433
+ER +++ + R+DK
Sbjct: 175 RKKERKEKKKEEK-RREDK 192
Score = 33.9 bits (76), Expect = 2.3
Identities = 42/167 (25%), Positives = 66/167 (39%), Gaps = 33/167 (19%)
Query: 1135 EKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEA-RERDWFPDQGYRGRGRGEY 1193
EK+ E+ +D +R R R ++ R ++ RERD D R R R
Sbjct: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD---RERKRETD 109
Query: 1194 YSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEV 1253
+R R+ +G GR + + RD R+RE R
Sbjct: 110 RNRERNRKG--------GRERDKQTERERD-------------RERERQRQRER------ 142
Query: 1254 VPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVK 1300
+R+RQR + +TD E A ++ + K +++ER E KK K
Sbjct: 143 --ERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEK 187
Score = 33.5 bits (75), Expect = 3.0
Identities = 30/136 (22%), Positives = 54/136 (39%), Gaps = 13/136 (9%)
Query: 915 VESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIR 974
+E Q RKR G ++ D QR + + R D +R ++ K
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK------ 54
Query: 975 SSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEERE----- 1029
E + ++ + + R R + +RE R +R ++ RD + +RE
Sbjct: 55 --ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
Query: 1030 QRKEKEGEKAEKVTEK 1045
+R K G + +K TE+
Sbjct: 113 ERNRKGGRERDKQTER 128
Score = 32.3 bits (72), Expect = 6.8
Identities = 32/162 (19%), Positives = 64/162 (39%), Gaps = 12/162 (7%)
Query: 908 QEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKP 967
Q ER + E + ++ H Q E+ E + R +++ ER E+
Sbjct: 24 QRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQ 83
Query: 968 KKEGFIRSSEGPKPE--------KVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKP 1019
++ R ++ + + + +++ R G R + E DR R ++
Sbjct: 84 RQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERE 143
Query: 1020 VLRDMKEEREQRKEK----EGEKAEKVTEKVVVKPEKTEKKD 1057
R + +RE +E+ E E+ +K +K K K +KK+
Sbjct: 144 RQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKE 185
Score = 32.0 bits (71), Expect = 8.9
Identities = 33/157 (21%), Positives = 57/157 (36%), Gaps = 20/157 (12%)
Query: 900 DQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEP 959
D++T + ER + Q R+R + ++ QR + T R D
Sbjct: 47 DRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERK-----RQTDRERDKDRD 101
Query: 960 IERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKP 1019
ER E + R + ++ + + R R R+ +R
Sbjct: 102 RERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERK---------- 151
Query: 1020 VLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKK 1056
R+ ER++ E+E K E+ E+ K E+ EKK
Sbjct: 152 --RETDRERQRWAEREERKKERKKER---KKERKEKK 183
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 108 bits (270), Expect = 7e-23
Identities = 75/272 (27%), Positives = 154/272 (56%), Gaps = 41/272 (15%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA-ACAEKLKRLDEKLGILEKQ- 498
E+++W+Q + Q + E+ K RE+EE+ ++ K EK++ ++K+ E++
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 499 -PSPEEIREREREKEREREKELEK-----EQEQEREKEREKDRERQQEKEKELEKEQEKQ 552
E+IRE+E + R+ EK E+ EQE+E ++ EK RE+++++++++ ++++K
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415
Query: 553 REMEKERKQEKEKELERQKEKEKELQKM------KEQEKECELEKEREKL---EEKIEPR 603
RE + E+ +E+E+E+ RQ+EK +EL++M K +E E ++++E EK+ EEKI+ +
Sbjct: 416 REQD-EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 604 EPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGY 663
E ++ EK + K+EE ++ +++ ++E + E E + Q
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK---MWEQEEKMQEQEE------- 524
Query: 664 FKQFQKSLPPRFQRQQEQMKQQQ---WQQQQQ 692
+ QRQ+E+M++Q+ WQQ+++
Sbjct: 525 ----------KMQRQEEKMREQEVRLWQQEEK 546
Score = 103 bits (256), Expect = 3e-21
Identities = 83/285 (29%), Positives = 150/285 (52%), Gaps = 35/285 (12%)
Query: 441 EDEIWKQRRRQQSEISAAVERARK--------RREEEERRMEEQRKAACAEKLKRLDEKL 492
E+++W+Q + + E+ K R +EE+ R +E++ EK++ DEK+
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 493 GILEKQP--SPEEIREREREKEREREKELEKEQEQEREKEREKDRE--RQQEKEKELEK- 547
E++ E+IRE+E EK +E+ EK+ ++ EK RE++ E RQ+EK +ELE+
Sbjct: 384 QEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 548 ---EQEKQREM------EKERKQEKEKELERQKEKEKELQK--------MKEQEKECELE 590
++EK RE+ E+E+ QE+E++++RQ+EK +E ++ +K++EK E E
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 591 KEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
++ + EEK+ +E ++ EK + + +E+E +Q+ E+E + E E
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR--LQELEER 560
Query: 651 SGSQPRPAVLSGYF--KQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
G + A L G + + LP Q ++K Q+ Q QQQ
Sbjct: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605
Score = 87.8 bits (216), Expect = 1e-16
Identities = 85/286 (29%), Positives = 140/286 (48%), Gaps = 60/286 (20%)
Query: 441 EDEIWKQRR--RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQ 498
E+++W+Q R+Q E E R+EE+ R EE+R+ EK+ R ++K+ +
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ----EKMWRQEKKM-----R 416
Query: 499 PSPEEIREREREKEREREK--ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556
E+IRE+E E R+ EK ELE+ + + EK RE + + Q+E+EK E+E++ QR+ E
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 557 KERKQEK------------------EKELERQKEKEKELQKMKEQEKECELEKEREKLEE 598
K ++QE+ E+++ RQ+EK E ++EK E E++ ++ EE
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE-----QEEKMQEQEEKMQRQEE 531
Query: 599 KIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEK--EATPVVHETEPESGSQPR 656
K+ +E L EK +E+ V ++ R K + ++ ESGSQ
Sbjct: 532 KMREQEVRLWQQEEKM--------QEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
Query: 657 PAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQ--QGVLPQTV 700
P +L P Q + + + Q QQQQ +G L Q V
Sbjct: 584 P------------TLTPILQVELKSQEAQSLQQQQDHYRGHLQQYV 617
Score = 84.0 bits (206), Expect = 2e-15
Identities = 75/328 (22%), Positives = 166/328 (50%), Gaps = 22/328 (6%)
Query: 292 ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSE 351
ER +L + +++ D L E A Q +V+ E N + ++ +E +
Sbjct: 249 ERAQLLLPQQQLQVEA-DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
Query: 352 DQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPK 411
+Q K E +E +E + ++ Q K+ + + QE + +
Sbjct: 308 EQEEKMCEQELKIREQEE-KMWRQEEKMHEQEE--KIREQEDKMWRQEE----KIREQEE 360
Query: 412 LLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQR---RRQQSEISAAVERARKRREE 468
+ +Q RQ R ++Q E+E+W+Q R Q+ + + R K+ E
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQ---EEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 469 EERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE-REKEREREKELEKEQEQ-E 526
++ ++ EQ E++ R +EK+ LE+ +E + RE EK +E E+++++++E+ +
Sbjct: 418 QDEKIREQE-----EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
R++E+ +++E + ++++L K++EK E E++ +++EK E++++ +++ +KM+ QE++
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 587 C-ELEKEREKLEEKIEPREPNLEPMVEK 613
E E + EEK++ +E L+ + E+
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEER 560
Score = 82.0 bits (201), Expect = 7e-15
Identities = 50/171 (29%), Positives = 109/171 (63%), Gaps = 13/171 (7%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRK-AACAEKLKRLDEKLG 493
+Q+ ++++W+Q ++ + E+ K RE+EE ++ K E ++ +EKL
Sbjct: 399 EQEEKRQEKMWRQEKKMR-------EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 494 ILEKQPSPEEIREREREKEREREKELEKEQEQE--REKEREKDRERQQEKEKELEKEQEK 551
+E++ EE + +E+E++ +R++E +EQE++ R+++ K E+ E+E+++ +++EK
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Query: 552 QREMEKERKQEKEKELERQKEK--EKELQKMKEQEKECELEKEREKLEEKI 600
E E E+ QE+E++++RQ+EK E+E++ +++EK E E ++LEE++
Sbjct: 512 MWEQE-EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 77.0 bits (188), Expect = 2e-13
Identities = 61/283 (21%), Positives = 144/283 (50%), Gaps = 24/283 (8%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKL-KRLDEKLG 493
K++ A+ E + ++SEI V+ +++ E + + +Q+ A++L K L
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276
Query: 494 ILEKQPSPEEI-----REREREKEREREKELEKEQE--------QEREKEREKDRERQQE 540
L+ Q E+ +++E + R+ EK E+E++ +E+E++ + E+ E
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE 336
Query: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQ-----EKECELEKEREK 595
+E+++ ++++K E++ ++++EK E++++ ++ +K++EQ E+E E+ ++ EK
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 596 LEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQP 655
+ E+ E R+ + +K ++ +E+E RQ+ E E E + +
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 656 RPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQ 698
+Q +K QRQ+E++++Q+ + +Q+ +L Q
Sbjct: 457 MQEEEEKMQEQEEK-----IQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 69.3 bits (168), Expect = 5e-11
Identities = 63/275 (22%), Positives = 127/275 (46%), Gaps = 33/275 (12%)
Query: 466 REEEERRMEEQRKAACAEKLKR----LDEKLGILEKQPSPEEIREREREKEREREKELEK 521
+E + +E R E+LK L EKL ++E + S ++ ++ +++ ER + L
Sbjct: 197 KERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLP 256
Query: 522 EQEQEREKER-------EKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKE 574
+Q+ + E +R + + Q +E EL +Q+E + R++EK +E E +K E
Sbjct: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE-EKMCE 315
Query: 575 KELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK-QESENSCNKEEEPVFTRQDS 633
+EL+ +++EK E++ + EEKI +E + EK +E E ++EE ++ +++
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 634 NRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
R + E + E E E Q + + Q+E+ +++ W+Q+++
Sbjct: 376 IREQDEK---IQEQEEEMWRQEE-----------------KIREQEEKRQEKMWRQEKKM 415
Query: 694 GVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHL 728
+ + Q R L + MQ + L
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Score = 49.7 bits (117), Expect = 4e-05
Identities = 65/301 (21%), Positives = 128/301 (42%), Gaps = 48/301 (15%)
Query: 433 PSKQQVADEDEIWKQRRRQQSEISAAVE----RARKRREEEERRMEEQRKAACAEKLKRL 488
P ++ +ADE Q SE+ A +E R KR +E++ E + C E LKR+
Sbjct: 53 PREKSIADEKFF------QLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRV 106
Query: 489 D---------EKLGILEKQPSPEEIR---EREREKEREREKELEKEQEQEREKEREKDRE 536
E G+ + + +E++ ++ +EK E+ K ++ R +
Sbjct: 107 TFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVT 166
Query: 537 RQQEKEKELEKEQ----------------EKQRE---MEKERKQEKEKELERQKEKEKEL 577
Q+ E L +E K+R+ +E R ++EL+ + + +E
Sbjct: 167 AQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEK 226
Query: 578 QKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
++ E EK E++ + L+ K+E R L P + Q + KE + V + + E
Sbjct: 227 LRLVESEKS-EIQLNVKDLKRKLE-RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEE 284
Query: 638 KEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQ-----RQQEQMKQQQWQQQQQ 692
E ++++ + E + + K ++ L R Q RQ+E+M +Q+ + ++Q
Sbjct: 285 NELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ 344
Query: 693 Q 693
+
Sbjct: 345 E 345
Score = 37.7 bits (86), Expect = 0.16
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 15/159 (9%)
Query: 908 QEERISAVESQPSRKRS-VSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEK 966
QEE+I E + R+ + ++ +E+ I + + + +E + R EEK
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 967 PKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEV-----NDRPVRRSGPIKKPVL 1021
IR E + EK+++ + + R + EE+ R + ++ L
Sbjct: 397 ------IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 1022 RDMKEEREQRKEKEGEKAEKV---TEKVVVKPEKTEKKD 1057
R+++E+ ++ +EK E+ EK+ EK+ + EKT +++
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 108 bits (270), Expect = 7e-23
Identities = 75/272 (27%), Positives = 154/272 (56%), Gaps = 41/272 (15%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA-ACAEKLKRLDEKLGILEKQ- 498
E+++W+Q + Q + E+ K RE+EE+ ++ K EK++ ++K+ E++
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 499 -PSPEEIREREREKEREREKELEK-----EQEQEREKEREKDRERQQEKEKELEKEQEKQ 552
E+IRE+E + R+ EK E+ EQE+E ++ EK RE+++++++++ ++++K
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415
Query: 553 REMEKERKQEKEKELERQKEKEKELQKM------KEQEKECELEKEREKL---EEKIEPR 603
RE + E+ +E+E+E+ RQ+EK +EL++M K +E E ++++E EK+ EEKI+ +
Sbjct: 416 REQD-EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 604 EPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGY 663
E ++ EK + K+EE ++ +++ ++E + E E + Q
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK---MWEQEEKMQEQEE------- 524
Query: 664 FKQFQKSLPPRFQRQQEQMKQQQ---WQQQQQ 692
+ QRQ+E+M++Q+ WQQ+++
Sbjct: 525 ----------KMQRQEEKMREQEVRLWQQEEK 546
Score = 103 bits (256), Expect = 3e-21
Identities = 83/285 (29%), Positives = 150/285 (52%), Gaps = 35/285 (12%)
Query: 441 EDEIWKQRRRQQSEISAAVERARK--------RREEEERRMEEQRKAACAEKLKRLDEKL 492
E+++W+Q + + E+ K R +EE+ R +E++ EK++ DEK+
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 493 GILEKQP--SPEEIREREREKEREREKELEKEQEQEREKEREKDRE--RQQEKEKELEK- 547
E++ E+IRE+E EK +E+ EK+ ++ EK RE++ E RQ+EK +ELE+
Sbjct: 384 QEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 548 ---EQEKQREM------EKERKQEKEKELERQKEKEKELQK--------MKEQEKECELE 590
++EK RE+ E+E+ QE+E++++RQ+EK +E ++ +K++EK E E
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 591 KEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
++ + EEK+ +E ++ EK + + +E+E +Q+ E+E + E E
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR--LQELEER 560
Query: 651 SGSQPRPAVLSGYF--KQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
G + A L G + + LP Q ++K Q+ Q QQQ
Sbjct: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605
Score = 87.8 bits (216), Expect = 1e-16
Identities = 85/286 (29%), Positives = 140/286 (48%), Gaps = 60/286 (20%)
Query: 441 EDEIWKQRR--RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQ 498
E+++W+Q R+Q E E R+EE+ R EE+R+ EK+ R ++K+ +
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ----EKMWRQEKKM-----R 416
Query: 499 PSPEEIREREREKEREREK--ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556
E+IRE+E E R+ EK ELE+ + + EK RE + + Q+E+EK E+E++ QR+ E
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 557 KERKQEK------------------EKELERQKEKEKELQKMKEQEKECELEKEREKLEE 598
K ++QE+ E+++ RQ+EK E ++EK E E++ ++ EE
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE-----QEEKMQEQEEKMQRQEE 531
Query: 599 KIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEK--EATPVVHETEPESGSQPR 656
K+ +E L EK +E+ V ++ R K + ++ ESGSQ
Sbjct: 532 KMREQEVRLWQQEEKM--------QEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
Query: 657 PAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQ--QGVLPQTV 700
P +L P Q + + + Q QQQQ +G L Q V
Sbjct: 584 P------------TLTPILQVELKSQEAQSLQQQQDHYRGHLQQYV 617
Score = 84.0 bits (206), Expect = 2e-15
Identities = 75/328 (22%), Positives = 166/328 (50%), Gaps = 22/328 (6%)
Query: 292 ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSE 351
ER +L + +++ D L E A Q +V+ E N + ++ +E +
Sbjct: 249 ERAQLLLPQQQLQVEA-DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
Query: 352 DQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPK 411
+Q K E +E +E + ++ Q K+ + + QE + +
Sbjct: 308 EQEEKMCEQELKIREQEE-KMWRQEEKMHEQEE--KIREQEDKMWRQEE----KIREQEE 360
Query: 412 LLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQR---RRQQSEISAAVERARKRREE 468
+ +Q RQ R ++Q E+E+W+Q R Q+ + + R K+ E
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQ---EEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 469 EERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE-REKEREREKELEKEQEQ-E 526
++ ++ EQ E++ R +EK+ LE+ +E + RE EK +E E+++++++E+ +
Sbjct: 418 QDEKIREQE-----EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
R++E+ +++E + ++++L K++EK E E++ +++EK E++++ +++ +KM+ QE++
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 587 C-ELEKEREKLEEKIEPREPNLEPMVEK 613
E E + EEK++ +E L+ + E+
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEER 560
Score = 82.0 bits (201), Expect = 7e-15
Identities = 50/171 (29%), Positives = 109/171 (63%), Gaps = 13/171 (7%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRK-AACAEKLKRLDEKLG 493
+Q+ ++++W+Q ++ + E+ K RE+EE ++ K E ++ +EKL
Sbjct: 399 EQEEKRQEKMWRQEKKMR-------EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 494 ILEKQPSPEEIREREREKEREREKELEKEQEQE--REKEREKDRERQQEKEKELEKEQEK 551
+E++ EE + +E+E++ +R++E +EQE++ R+++ K E+ E+E+++ +++EK
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Query: 552 QREMEKERKQEKEKELERQKEK--EKELQKMKEQEKECELEKEREKLEEKI 600
E E E+ QE+E++++RQ+EK E+E++ +++EK E E ++LEE++
Sbjct: 512 MWEQE-EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 77.0 bits (188), Expect = 2e-13
Identities = 61/283 (21%), Positives = 144/283 (50%), Gaps = 24/283 (8%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKL-KRLDEKLG 493
K++ A+ E + ++SEI V+ +++ E + + +Q+ A++L K L
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276
Query: 494 ILEKQPSPEEI-----REREREKEREREKELEKEQE--------QEREKEREKDRERQQE 540
L+ Q E+ +++E + R+ EK E+E++ +E+E++ + E+ E
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE 336
Query: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQ-----EKECELEKEREK 595
+E+++ ++++K E++ ++++EK E++++ ++ +K++EQ E+E E+ ++ EK
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 596 LEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQP 655
+ E+ E R+ + +K ++ +E+E RQ+ E E E + +
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 656 RPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQ 698
+Q +K QRQ+E++++Q+ + +Q+ +L Q
Sbjct: 457 MQEEEEKMQEQEEK-----IQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 69.3 bits (168), Expect = 5e-11
Identities = 63/275 (22%), Positives = 127/275 (46%), Gaps = 33/275 (12%)
Query: 466 REEEERRMEEQRKAACAEKLKR----LDEKLGILEKQPSPEEIREREREKEREREKELEK 521
+E + +E R E+LK L EKL ++E + S ++ ++ +++ ER + L
Sbjct: 197 KERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLP 256
Query: 522 EQEQEREKER-------EKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKE 574
+Q+ + E +R + + Q +E EL +Q+E + R++EK +E E +K E
Sbjct: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE-EKMCE 315
Query: 575 KELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK-QESENSCNKEEEPVFTRQDS 633
+EL+ +++EK E++ + EEKI +E + EK +E E ++EE ++ +++
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 634 NRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
R + E + E E E Q + + Q+E+ +++ W+Q+++
Sbjct: 376 IREQDEK---IQEQEEEMWRQEE-----------------KIREQEEKRQEKMWRQEKKM 415
Query: 694 GVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHL 728
+ + Q R L + MQ + L
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Score = 49.7 bits (117), Expect = 4e-05
Identities = 65/301 (21%), Positives = 128/301 (42%), Gaps = 48/301 (15%)
Query: 433 PSKQQVADEDEIWKQRRRQQSEISAAVE----RARKRREEEERRMEEQRKAACAEKLKRL 488
P ++ +ADE Q SE+ A +E R KR +E++ E + C E LKR+
Sbjct: 53 PREKSIADEKFF------QLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRV 106
Query: 489 D---------EKLGILEKQPSPEEIR---EREREKEREREKELEKEQEQEREKEREKDRE 536
E G+ + + +E++ ++ +EK E+ K ++ R +
Sbjct: 107 TFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVT 166
Query: 537 RQQEKEKELEKEQ----------------EKQRE---MEKERKQEKEKELERQKEKEKEL 577
Q+ E L +E K+R+ +E R ++EL+ + + +E
Sbjct: 167 AQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEK 226
Query: 578 QKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
++ E EK E++ + L+ K+E R L P + Q + KE + V + + E
Sbjct: 227 LRLVESEKS-EIQLNVKDLKRKLE-RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEE 284
Query: 638 KEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQ-----RQQEQMKQQQWQQQQQ 692
E ++++ + E + + K ++ L R Q RQ+E+M +Q+ + ++Q
Sbjct: 285 NELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ 344
Query: 693 Q 693
+
Sbjct: 345 E 345
Score = 37.7 bits (86), Expect = 0.16
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 15/159 (9%)
Query: 908 QEERISAVESQPSRKRS-VSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEK 966
QEE+I E + R+ + ++ +E+ I + + + +E + R EEK
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 967 PKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEV-----NDRPVRRSGPIKKPVL 1021
IR E + EK+++ + + R + EE+ R + ++ L
Sbjct: 397 ------IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 1022 RDMKEEREQRKEKEGEKAEKV---TEKVVVKPEKTEKKD 1057
R+++E+ ++ +EK E+ EK+ EK+ + EKT +++
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 108 bits (270), Expect = 7e-23
Identities = 76/282 (26%), Positives = 150/282 (53%), Gaps = 33/282 (11%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEER-RMEEQRKAACAEKLKRLDEKLG------ 493
E+++W+Q + Q E+ K RE+EE+ R +E+ EK++R +E +
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 494 --ILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEK 551
+ EK E+IRE+E EK +E EK E+E+ QE+E + + E+ +E+E+++ +++E
Sbjct: 347 RELEEKMHEQEKIREQE-EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 552 QREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC-ELEKEREKLEEKIEPREPNLEPM 610
+E E++ +++EK E+++E +++ +KM+ QE++ E EK+ + EEKI +E ++
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 611 VEK---------------QESENSCNKEEEPVFTRQDSNRSE----KEATPVVHETEPES 651
EK QE E ++EE + ++ R + +E ++ E E +
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 652 GSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
Q Q Q+ + +RQ+E+M++Q+ + +QQ+
Sbjct: 526 WEQEEKMCEQEEKMQEQEE---KMRRQEEKMREQEVRLRQQE 564
Score = 93.6 bits (231), Expect = 2e-18
Identities = 80/333 (24%), Positives = 163/333 (48%), Gaps = 33/333 (9%)
Query: 309 DNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETD 368
D+L E A Q +V+ E N + ++ +E +++ K E E +E +
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE 315
Query: 369 EVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGR 428
E + + + + + R + K+ Q+
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE----------- 364
Query: 429 PGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRL 488
K+Q +E++I +Q +RQ+ E A+ R+EE+ R +E++ E ++
Sbjct: 365 ------KRQ--EEEKIREQEKRQEQE-------AKMWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKE 548
+EK+G E++ +E +E+E++ R++E +EQE++ ++ EK RE+++ +++ EK
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 549 QEKQREM-EKERK-QEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPN 606
E++ +M E+E K QE+E+++ RQ+EK +E Q+ K +E+E ++ ++ E ++E+ E
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIRE-QEKKIREQEEKIREQEEMMQEQEEKMWEQ 528
Query: 607 LEPMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639
E M E++E +E+E RQ+ E+E
Sbjct: 529 EEKMCEQEEK----MQEQEEKMRRQEEKMREQE 557
Score = 93.2 bits (230), Expect = 3e-18
Identities = 70/278 (25%), Positives = 148/278 (53%), Gaps = 33/278 (11%)
Query: 433 PSKQQVADEDEIWKQRRRQQSEISAAVERAR---KRREEEERRMEEQRKAACAEKLKRLD 489
P +Q A+ D + K+ + +++ A VE + +++E +M Q EK++ +
Sbjct: 247 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE-----EKIQERE 301
Query: 490 EKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549
EK+ Q E+IRE+E + R+ E EKE++ R++E ++E EK +ELE++
Sbjct: 302 EKI-----QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKIRELEEKM 353
Query: 550 EKQREM-EKERKQEKEKEL-ERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNL 607
+Q ++ E+E K+++E+++ E++K +E+E + +++EK E E++ + EE ++ +E +
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 608 EPMVEK--------QESENSCNKEEEPVFTRQDSNRSE----KEATPVVHETEPESGSQP 655
EK QE E ++EE + ++ R + +E ++ E E + G Q
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 656 RPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
Q Q+ + +RQ+E++++Q+ + ++Q+
Sbjct: 474 GKMCEQEAKMQEQEE---KMRRQEEKIREQEKKIREQE 508
Score = 89.4 bits (220), Expect = 5e-17
Identities = 67/264 (25%), Positives = 136/264 (51%), Gaps = 33/264 (12%)
Query: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKL-KRLDEKLGILEKQPSPEEIRER-- 507
++SEI V+ +++ E + + +Q+ A A+ L K L L+ Q E+ R
Sbjct: 224 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 283
Query: 508 ---------EREKEREREKELEKEQEQEREKEREKDRERQQ--EKEKELEKEQEKQREME 556
+ EK +ERE+++++++E+ RE+E + R+ + EKE+++ +++E E E
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343
Query: 557 K-----ERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMV 611
+ E K +++++ Q+EK +E +K++EQEK E E + + EEKI +E +
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 612 E-KQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKS 670
E QE E ++EE ++ +++ + ++E E E + R +Q +K
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR--------EQEEK- 454
Query: 671 LPPRFQRQQEQMKQQQWQQQQQQG 694
+ Q+E M++Q+ + +Q+G
Sbjct: 455 ----IREQEEMMQEQEEKMGEQEG 474
Score = 80.1 bits (196), Expect = 3e-14
Identities = 47/163 (28%), Positives = 99/163 (60%), Gaps = 15/163 (9%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRK--AACAEKLKRLDEKLGILEKQ 498
E+++W+Q Q + + R ++ E+E+++ EQ + E ++ +EK+G E +
Sbjct: 417 EEKMWEQEEEMQEQ-EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK 475
Query: 499 PSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQ---QEKEKELEKEQEKQREM 555
+E + +E+E++ R++E +EQE++ ++ EK RE++ QE+E+++ +++EK E
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 535
Query: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEE 598
E E+ QE+E+++ RQ+EK + E+E L ++ EK++E
Sbjct: 536 E-EKMQEQEEKMRRQEEKMR--------EQEVRLRQQEEKMQE 569
Score = 74.7 bits (182), Expect = 1e-12
Identities = 66/286 (23%), Positives = 138/286 (48%), Gaps = 32/286 (11%)
Query: 445 WKQRRRQQSEISAAVERARKR--------REEEERRMEEQRKAACAEKLK----RLDEKL 492
WK + +SA + +K +E + +E R E+LK +L EKL
Sbjct: 159 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKL 218
Query: 493 GILEKQPSPEEIREREREKEREREKELEKEQEQERE-----KEREKDRERQQEKEKE--- 544
++E + S ++ +E +++ ER K L +Q+ + E KE + + Q + +E
Sbjct: 219 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 278
Query: 545 ---LEKEQEKQREMEKERKQEKEKELERQKEKEKELQ-KMKEQ-----EKECELEKEREK 595
L ++QE++ ++E+ QE+E++++ Q+EK +E + KM+ Q EKE ++ ++ E
Sbjct: 279 WNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 338
Query: 596 LEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHE---TEPESG 652
+ EK E E M E+++ K +E R+ R E+EA E E E
Sbjct: 339 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 398
Query: 653 SQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQ 698
+ + ++ ++ + +++++E +Q++ ++Q++ + Q
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Score = 43.9 bits (102), Expect = 0.002
Identities = 48/250 (19%), Positives = 106/250 (42%), Gaps = 18/250 (7%)
Query: 817 PQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQV-QKFL 875
PQQ +A ++++S +A Q Q+ + N+L + R+ + Q ++ +
Sbjct: 247 PQQQLQAEADHLGKELQSVSAKLQAQVEE--NELWNRLNQQQEEKMWRQEEKIQEREEKI 304
Query: 876 SRSVEDVRPHHTDANNQSACFEAPDQKT-----LSAPQEERISAVESQPSRKRSVSHGSN 930
E +R Q ++K + +EE+I +E + + +
Sbjct: 305 QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364
Query: 931 HTQKPD-----EQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVY 985
Q+ + E+R E A + + + + +E I EE +++ G + EK++
Sbjct: 365 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ---EEKMGEQEEKMW 421
Query: 986 KSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEK 1045
+ + E + + RR+E R + ++ +R+ +E ++++EK GE+ K+ E+
Sbjct: 422 EQEEEMQ--EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 1046 VVVKPEKTEK 1055
E+ EK
Sbjct: 480 EAKMQEQEEK 489
Score = 37.7 bits (86), Expect = 0.16
Identities = 49/232 (21%), Positives = 96/232 (41%), Gaps = 30/232 (12%)
Query: 827 EEPEDVRS--EAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKF-LSRSVEDVR 883
E+ E +R E +QE+I Q E + + IRE + Q Q+ + R E +R
Sbjct: 341 EKEEKIRELEEKMHEQEKI-------REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 884 PHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPS 943
Q + ++K QEE++ E + + ++ +E+ E
Sbjct: 394 EQEEKIREQEEMMQEQEEKM--GEQEEKMWEQEEEMQEQEE------KMRRQEEKIREQE 445
Query: 944 AGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRRE 1003
I + + + +E ++ EEK ++ EG E+ E + + RR+
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQ------EGKMCEQ------EAKMQEQEEKMRRQ 493
Query: 1004 EVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEK 1055
E R + ++ +R+ +E ++++EK E+ EK+ E+ E+ EK
Sbjct: 494 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Score = 37.7 bits (86), Expect = 0.16
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 436 QQVADEDEIWKQRRRQQSEISAAVERARK-----RREEEERRMEEQRKAACAEKLKRLDE 490
+Q A E ++ RRQ+ +I ++ R+ R +EE + +E++ EK+ +E
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 491 KLGILEKQPSPEEIREREREKEREREKELEKEQEQERE 528
K+ EE R+ EK RE+E L +++E+ +E
Sbjct: 538 KM------QEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 106 bits (265), Expect = 3e-22
Identities = 182/803 (22%), Positives = 262/803 (32%), Gaps = 105/803 (13%)
Query: 1717 KGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTS-------ASVPASTSAP 1769
KG + LP A + + + P L AP PP+ + + P+ AP
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 1770 LPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLA---PVSASASVSASVPASTSAA 1826
+P TP P AP + + P P LA P A + +A+ P+
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 1827 AITSSSAPASAPAPTPIL----ASVSTPASVTILASASIPILASALASTS---APTPAPA 1879
A + PA TP + +P +A+ P LA+ S APT PA
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPA 1222
Query: 1880 ASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQ----AQ 1935
A+ P+ A P APT P+ PA P P AP P P +
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA-TPPPKGAPTPPAATPPSLKGGLATP 1281
Query: 1936 THKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNK 1995
HK NP T S K P + A TP + S TP G T
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT------- 1334
Query: 1996 VAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQ 2055
PPAV +PP P S P++ +K G T
Sbjct: 1335 --PPAV-----------TPPSPKGTPTLPATTPSSKGGPTTPSSKEG---------PTPP 1372
Query: 2056 FGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLP------DLSPVEN 2109
P+ G P S K IP PK P P+ +K P + + +
Sbjct: 1373 AATPSHKGGPAMTPP--SPKRGPAIPSPKGD-PTSPAVIPLSPKKAPATPVTREGAATPS 1429
Query: 2110 KEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIG 2169
K P SLK A + P T+ + P + KE A +++T
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
Query: 2170 --------------TMISV--SSAEYGTNAKESVTDYTTPSSSL-----PNTVATNNTKM 2208
T+ +V SS + S D P+++L P T+A +
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549
Query: 2209 EDTLVNNVPLPN---TLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVRE 2265
+ VP P +P PK SS S PP T+K + K P V
Sbjct: 1550 PPAM--TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607
Query: 2266 KGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSS 2325
SP + PP T S GP+T P +P + S TS
Sbjct: 1608 P-SPKEAPTPPAVT-PPSPEKGPAT-----------PAPKGTPTSPPVTPSSLKDSPTSP 1654
Query: 2326 LSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAA 2385
S + P K P + ++L P + A ++ PQ ++ ++A
Sbjct: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQ---TKKSSA 1711
Query: 2386 QIPAFYMDTSHLFNTQH--ARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQA 2443
P D S ++ + +AP L Q ++ P AP + +
Sbjct: 1712 TSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Query: 2444 QLSLGAGPAVSQAQELFSSSLQP 2466
L+ A V E S S P
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAP 1794
Score = 85.9 bits (211), Expect = 5e-16
Identities = 169/699 (24%), Positives = 237/699 (33%), Gaps = 107/699 (15%)
Query: 1745 SVPPLASAPLPPSTS-------ASVPASTSAPLPATLTP-----VPASTSAPVPASTLAP 1792
+ P AP PP+ + + P+ AP P +TP PA+T P AST
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 1793 VLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPIL----ASVS 1848
+ PA+ P A + +A++P+ A S + PA TP +
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 1849 TPASVTILASASIPILASALAS---TSAPT------PAPAASSPAAPVITAPTIPASAPT 1899
+P + +A+ P LA+ APT P+P P APT PA+ P
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 1900 A-----------SVPLAPASASAPAP-----APTPVSAP---------------NPAPPA 1928
+ P PA A+ P+P P+P AP P+P
Sbjct: 1158 SPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216
Query: 1929 PAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQS----- 1983
T A T + L T S P+ PS P G K TP +
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPS---PKGGPATPPPKGAPTPPAATPPS 1273
Query: 1984 -HGTLTAELWDNKVAP-PAVLNDISKKLGP-ISPPQPPSVSAWNKPLTSFGS--APSSEG 2038
G L +K AP PAV+ S K GP SPP+ P + GS P +G
Sbjct: 1274 LKGGLATP--PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Query: 2039 AKN--GQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPI 2096
A GT T+ P+S G S K P + P P
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPT----TPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 2097 KAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPA--TVRSTDPVT 2154
++ P + + P I + K A V EG PS T + PV+
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIP-----LSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 2155 TKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKME----D 2210
K+ A S T + G +VT + P VAT+++ +
Sbjct: 1443 LKKAPATSAPKGGPAT-----PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497
Query: 2211 TLVNNVPLPNTLP-LPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWEN-SPNVREKGS 2268
+ LP +P PK SS + PT L+ K + E P S
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 2269 PVTSTAPPI-----ATGVSSSASGPSTANYNSFSSASMPQ---IPVASVTPTASLSGAGT 2320
P + A P AT S AS P +++ A P+ IP A +P+ +
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Query: 2321 YTTSSLSTKSTTTSDP---PNICKVKPQQLQTSSLPSAS 2356
T K T P P V P L+ S AS
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656
Score = 84.3 bits (207), Expect = 2e-15
Identities = 170/856 (19%), Positives = 284/856 (33%), Gaps = 96/856 (11%)
Query: 1750 ASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPV 1809
A+ P P + P AP P TP P AP A + P P P
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG--GPA 1302
Query: 1810 SASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALA 1869
++ + + PA+T + S P APTP + +P L + +
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362
Query: 1870 STSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAP 1929
+S P P A++P+ A T P+ ++P ++PA P +P AP P
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL---SPKKAPATP 1419
Query: 1930 AQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTA 1989
+ T PP++ S + T G + + + TL A
Sbjct: 1420 VTREG----------AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
Query: 1990 ELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEI 2049
+ PPA + +P P + A P S + + +
Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
Query: 2050 GTDTIQFGAPASNGNENEVVP----VLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLS 2105
+ PA+ + ++P V S K IP PKE P K P
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE----APATPSSKEASSP--P 1583
Query: 2106 PVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMS 2165
V +K P KE + P +E P+P V T P K +
Sbjct: 1584 AVTPSTYKGAPSPKELLI------PPAVTSPSPKEAPTPPAV--TPPSPEKGPATPAPKG 1635
Query: 2166 TEIGTMISVSSAEYGTNAKESVT---DYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTL 2222
T ++ SS + + SVT T P +S T +++ LV P P +
Sbjct: 1636 TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLV--APAPEST 1693
Query: 2223 PL---PKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAP---- 2275
P+ P R+ Q S + PP + K S KG P+++ AP
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKNGS-------------KG-PLSTVAPAPLL 1739
Query: 2276 PIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTS- 2334
P+ S +A G ++ S P P S T + A + S + +
Sbjct: 1740 PVQKDSSKTAKGKDASH-----SPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP 1794
Query: 2335 DPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDT 2394
PP + P + T LP F L P L+ + P + +
Sbjct: 1795 SPPVSLPLAPSPVPT--LPPKQQF--LPSSPGLVLESPSKPLAPADEDELLPL------- 1843
Query: 2395 SHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVS 2454
+ P ++ FQ L + + IP+ P Q + + G+G S
Sbjct: 1844 ----------IPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSG-TES 1892
Query: 2455 QAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQTS 2514
+ E + +Q Q+ L+ + + + ++ KA S L +Q +
Sbjct: 1893 DSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVT 1952
Query: 2515 NTQPIPILYEHQL---GQASGLGGSQLIDTHLLQARA---NLTQASNLYSGQ---VQQPG 2565
+ I + + S DT+++ A +L+Q + L + + VQ
Sbjct: 1953 GVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA 2012
Query: 2566 QTNFYNTAQSPSALQQ 2581
+N Q+P+ ++
Sbjct: 2013 VSNIQENTQTPTVQEE 2028
Score = 82.4 bits (202), Expect = 6e-15
Identities = 215/989 (21%), Positives = 325/989 (32%), Gaps = 133/989 (13%)
Query: 1726 PPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTP--------V 1777
P A KQA + SS P A A P + P+ AP P TP
Sbjct: 900 PATPAPKQAPALSMTSSS---PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
Query: 1778 PASTSAPVPASTLAP-------VLASTSAPVPASPLAPVSASASVSASVPASTSAAAITS 1830
P+ AP P + P + AP P + P + S + + A+T
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016
Query: 1831 SSAPASAPAPTPILASVSTPASVTIL----ASASIPILASALASTSAPTPAPAASSPAAP 1886
S P +PA TP STP + T + A+ P+ A + +A P+P PA P
Sbjct: 1017 PS-PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP-KGGPATP 1074
Query: 1887 VIT-APTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQ 1945
+ APT PA+ P + P + +P AP P +A P+P T HK
Sbjct: 1075 SLKGAPTPPAATPPS--PKGGPATPSPKGAPMPPAATPPSPKGGLAT--PPHKGAPTTPA 1130
Query: 1946 TTSQSSK----QPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAV 2001
T S K PPP + TP T G + TP G T +P
Sbjct: 1131 ATPPSPKGGLATPPPK---GAPTTPAATPPSPKG-GLATPPPKGAPTTPA-ATPPSPKGG 1185
Query: 2002 LNDISKKLGPISPPQPP--------SVSAWNKPLTSFGSAPSSEG-----AKNGQESGLE 2048
L S K P +P P + S P T + PS +G + G +
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT-TP 1244
Query: 2049 IGTDTIQFGAPASNGNENEVVPVLSEKSADK----------IPEPKEQRQKQPRAGPIKA 2098
T G PA+ + P + + K P P P+ GP A
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP--A 1302
Query: 2099 QKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKET 2158
P +P P P G + P + P+P V P T
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGT-------------PPPKGAPTPPAVTPPSPKGTPTL 1349
Query: 2159 KAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNT---VATNNTKMEDTLVNN 2215
A + S G + SS E T + + P+ + P+ A + K + T
Sbjct: 1350 PATTPSSK--GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Query: 2216 VPL-PNTLPLP--KRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSP-NVREKGSP-- 2269
+PL P P RE S PP ++ K A A + P KG P
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 2270 -----------------VTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVA---SV 2309
TS++P A + P+ S +P P + +
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 2310 TPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIA 2369
PTA+L T ++L+ K PP + P+ +T ++P+ +
Sbjct: 1528 APTATL--LSKKTPATLAPKEALI--PPAMTVPSPK--KTPAIPTPKEAPATPSSKEASS 1581
Query: 2370 QQQQNPQVYVSQSAAAQ--IPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQ 2427
P Y + + IP S + PPS + PTS
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641
Query: 2428 QIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSG 2487
P + A ++ G V QA S P + P ++ L P+
Sbjct: 1642 VTPSSLKD--SPTSPASVTCKMGATVPQA-----SKGLPAKKGPTALKEVLVAPAP--ES 1692
Query: 2488 TAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQAR 2547
T I PT + + K+ + + P P G S + + L+ ++
Sbjct: 1693 TPIITAPTRKGPQTKKSSA-----TSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747
Query: 2548 -ANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIAL 2606
A AS+ G + P + +T + +A ++V ++ +S PL
Sbjct: 1748 TAKGKDASHSPKGPLAPP--ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805
Query: 2607 PQTLQPPLQHTTPQAQAQSLSRPAQVSQP 2635
P PP Q P + L P++ P
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
Score = 82.4 bits (202), Expect = 6e-15
Identities = 164/681 (24%), Positives = 248/681 (36%), Gaps = 104/681 (15%)
Query: 1717 KGRSQTSKLPPRFAKKQATGIQQA-QSSASVPPLASAPLPPSTSASVPASTSAPLPATLT 1775
KG TS PP+ A + + S PP AP PP+ + P T LPAT
Sbjct: 1298 KGGPATS--PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT-LPAT-- 1352
Query: 1776 PVPASTSAPV-PASTLAPVLASTSAPVPASP-LAPVSASASVSASVPASTSAAAITSSSA 1833
P+S P P+S P + + P + P S + P + +
Sbjct: 1353 -TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411
Query: 1834 PASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASS----PAAPVIT 1889
P APA +TP+ + A P+ +TSAP PA S P P +T
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 1890 APTIPASAPTASVPLAPASASAPAPA-PTPVSAPN-PA--PPAPAQTQAQTHKPVQNPLQ 1945
P+ P A +A +S+ APA P P+ AP PA P +P + A T ++P+
Sbjct: 1472 PPS--PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA-TPSSRRDPIA 1528
Query: 1946 TTSQ--SSKQP----------PPSIRLPSAQ------TPNGTDYVASGKSIQTPQSHGTL 1987
T+ S K P PP++ +PS + TP S K +P +
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS 1588
Query: 1988 T---AELWDNKVAPPAVLNDISKK------LGPISPPQPPSVSAWNKPLTSFGSAPSS-- 2036
T A + PPAV + K+ + P SP + P+ A TS PSS
Sbjct: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648
Query: 2037 EGAKNGQESGLEIGTDTIQF--GAPASNG----------NENEVVPVLSEKSADKIPEPK 2084
+ + ++G Q G PA G E P+++ + K P+ K
Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR-KGPQTK 1707
Query: 2085 EQRQKQPRAGPIKAQKLPDLSPVENKEHKP-GPIGKERSLKNRKVKDAQQVEPEGQEKPS 2143
+ P P + K P+ P P+ K+ S K K KDA P+G
Sbjct: 1708 KSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS-KTAKGKDASH-SPKG----- 1760
Query: 2144 PATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSL-----P 2198
P+ E+KA T ++ ++ E ES + PS + P
Sbjct: 1761 --------PLAPPESKA--------STPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804
Query: 2199 NTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWE 2258
+ V T K + L ++ L P + L +PP S +S
Sbjct: 1805 SPVPTLPPK-QQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQS---VLV 1860
Query: 2259 NSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQI----PVASVTPTAS 2314
N P + G PV + P V+ + G T S S S+P++ + T A
Sbjct: 1861 NMPTPKSAGIPVPT--PSAKQPVTKNNKGSGT---ESDSDESVPELEEQDSTQATTQQAQ 1915
Query: 2315 LSGAGTYTTSSLSTKSTTTSD 2335
L+ A +S + S+
Sbjct: 1916 LAAAAEIDEEPVSKAKQSRSE 1936
Score = 78.6 bits (192), Expect = 8e-14
Identities = 258/1187 (21%), Positives = 415/1187 (34%), Gaps = 195/1187 (16%)
Query: 1762 VPASTSAPLPATLT--PVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASV 1819
+P + +PAT P P + +A +P S+ V A+ P P P P + A +
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLP--PPCSPAPQQCPL 58
Query: 1820 PASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPA 1879
A+ A+ S S AS P P S +S T L + P + L + P +PA
Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQS----SSGTALPLGTAPEAPTFLPNLIGPPISPA 114
Query: 1880 ASSPAAPVITAPTI----PASAPTASVPLAPASASAPAPAPTPVSAPNP----------- 1924
A + A+P+I APT+ +SAP A V LAP S + P + P
Sbjct: 115 ALALASPMI-APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
Query: 1925 ---APPAPAQTQAQTHK----PVQNP---------LQTTSQSSKQPPPSIR-----LPSA 1963
AP AP++ + +K V NP + T P SI+ LP
Sbjct: 174 TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQT 233
Query: 1964 QTPNGTDYVASGKSIQT--------PQSHGTLTAELWDNKVAPPA----------VLNDI 2005
TP T +AS + T PQ+ G+L+ + V+PPA V+
Sbjct: 234 -TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLK---GPVSPPAALSLSTQSLPVVTSS 289
Query: 2006 SKKLGPISPPQ-PPSVSAWNKPL--TSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASN 2062
K GP +PP P S+ + PL +SFGS S + T ++ + ++
Sbjct: 290 QKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGAS 349
Query: 2063 -----------GNENEVVPV------LSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLS 2105
+ NEVVP + S DK P P +G + LS
Sbjct: 350 YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSP-SGSLNVATSFSLS 408
Query: 2106 PVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMS 2165
P + K P +A P + P + + VT T A + +
Sbjct: 409 PTTSLILKSSP-------------NATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT 455
Query: 2166 T-EIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPL 2224
T E+ T +S ++ S + T+P++ + VA + + + +P + PL
Sbjct: 456 TFEVATCVSPPM----SSGPISNIEPTSPAALVMAPVAPKEPSTQ--VATTLRIPVSPPL 509
Query: 2225 PKRETIQQSSS-----------LTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTST 2273
P E ++ S L +VP + F A + P V P+
Sbjct: 510 PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTV----LPLVQA 565
Query: 2274 APPIATGVSSSASGPS--TANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKST 2331
AP + S++S P + + + S+ + P+ P +S++ +S+ K+
Sbjct: 566 APKNSPSFQSTSSSPEIPLSPEATLAKKSLGE-PLPIGKPASSMTSPLGVNSSASVIKTD 624
Query: 2332 TTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFY 2391
+ + P + + L T P+ + F S P+ +A A+ + Y
Sbjct: 625 SYAGPDSAGPLLKSSLIT---PTVAAFPLESADPAGVA------------PTTAKGTSTY 669
Query: 2392 MDTSHLFNTQHARLAPPSLAQQQGFQPGLS-QPTSVQQIPIPIYAPLQGQHQAQL-SLGA 2449
T+ F LAP + ++G L PT+ + P+ AP A L +L
Sbjct: 670 TTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPV---APSPQNTCAPLATLVL 726
Query: 2450 GPAVSQAQELFSSSLQPYRSQPAFMQ-SSLSQPSVVLS-GTAIHNFPTVQHQELAKAQS- 2506
P + ++ + S SL P + P + +S S + ++ PT A A S
Sbjct: 727 APEIPKS--VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
Query: 2507 GLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHL--LQARANLTQASNLYSGQVQQP 2564
G + P+ + Q + GS DT + L + + +AS L +
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ 844
Query: 2565 GQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQP-------LIALPQTLQPPLQHT 2617
G + T SP+ P P++ L G T P ++ LP + P
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 2618 TPQAQAQSLSR---------------PAQVSQPFRGLIPAGTQHS----MIATTGKMSEM 2658
QA A S++ PA S PA T S + K +
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964
Query: 2659 ELKAFGSGIDIKPGTPPIAGRSTTPTSSP--FRATSTSPNSQSSKMNSIVYQKQFQSAPA 2716
A P TP G T P ++P + +P+ + + V + +PA
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 2717 TV-----RMTQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQSKQIGGGKAQKVDSDSSKPP 2771
T P T +P+ A L GG + + P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084
Query: 2772 ET---------LTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQA 2809
T P G P P +AT P + P P A
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
Score = 73.9 bits (180), Expect = 2e-12
Identities = 149/617 (24%), Positives = 206/617 (33%), Gaps = 72/617 (11%)
Query: 1747 PPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPL 1806
PP P T +S +P+ A+ P S S +P A+T +P P SP
Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEASFLP---ENSLSFQGSKDSP--ATTHSPTPPSPK 862
Query: 1807 APVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILAS 1866
+ SA S T T + + + P P A+ + + + ++S P A
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 1867 ALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAP 1926
A T AP PA+ SP APT PA+ P + P + +P APTP +A P+P
Sbjct: 923 A---TPAPKGIPASPSPKG----APTPPAATPPS--PKGGPATPSPKWAPTPPAATPPSP 973
Query: 1927 PAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGT 1986
T + P P T S K P + A TP ++ P G+
Sbjct: 974 KGGPATPSPKGAP--TPPAATPPSPKGGPATPSPKGAPTP---------PAVTPPSPKGS 1022
Query: 1987 LTAELWDNKVAPPAVLNDISKKLGPISPPQP---PSVSAWNKPLTSFGSA-PSSEGAKNG 2042
A + + P S K P + P P P+ A P G A PS +GA
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 2043 QESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLP 2102
+ T G PA+ + +P A P PK P G A P
Sbjct: 1083 PAA-----TPPSPKGGPATPSPKGAPMP-----PAATPPSPKGGLATPPHKG---APTTP 1129
Query: 2103 DLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEG-----QEKPSPATVRSTDPVTTKE 2157
+P K P K A P+G K +P T +T P
Sbjct: 1130 AATPPSPKGGLATPPPKGAP----TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 2158 TKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNT---VATNNTKMEDTLVN 2214
S + S + G TTP+++ P+ +AT + K T
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245
Query: 2215 NVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPN------VREKGS 2268
P P PK PP + K A + +PN KG
Sbjct: 1246 ATP-----PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 2269 PVTS-----TAPPIATGVSSSAS-GPSTANYNSFSSASMPQIPVASVT-PTASLSGAGTY 2321
P TS PP AT S S G A P P + T P + S G
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 2322 TTSSLSTKSTTTSDPPN 2338
TT S T + P+
Sbjct: 1361 TTPSSKEGPTPPAATPS 1377
Score = 73.9 bits (180), Expect = 2e-12
Identities = 176/784 (22%), Positives = 253/784 (32%), Gaps = 144/784 (18%)
Query: 1741 QSSASVPPLASAPLPPSTSASVPASTSAPL-------PATLTPVPASTSAP-------VP 1786
Q S P +P PPS + S PL P TP P+ + P P
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 1787 ASTLAPVLASTSAP------VPASPLAPVSASASVSASVPAST--SAAAITSSSAPASAP 1838
A AP L+ TS+ PA P S S + + PA+T S ++ +P AP
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Query: 1839 APTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAP 1898
P +TP S + P APTP PAA+ P+ A P AP
Sbjct: 964 TP-----PAATPPSPKGGPATPSP--------KGAPTP-PAATPPSPKGGPATPSPKGAP 1009
Query: 1899 TASVPLAPASASAPAPAPTPVSAPNP---APPAPAQTQAQTHKPVQNPL--QTTSQSSKQ 1953
T P+ +PA P P A P PP+P + A T P P T S K
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS 2013
P + L A TP + TP G PPA S K G +
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGA---------PMPPAA-TPPSPKGGLAT 1119
Query: 2014 PPQ--PPSVSAWNKPLTSFGSA-PSSEGA-----------KNGQESGLEIGTDTIQFGAP 2059
PP P+ A P G A P +GA K G + G T P
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 2060 ASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGK 2119
S L+ S P P+ G A P +P P P G
Sbjct: 1180 PSPKGG------LATPSPKGAPTTPAATPPSPKGG--LATPSPKGAPTTPAATPPSPKGG 1231
Query: 2120 ERSLKNRKVKDAQQVEPEGQE--------KPSPATVRSTDPVTTKETKAVSEMSTEIGTM 2171
+ + P + K +P +T P +
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV 1291
Query: 2172 ISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQ 2231
++ S + G T P+++ P+ + T P P P P T
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT----------PPPKGAPTPPAVTPP 1341
Query: 2232 QSSSLTSVPPTTFSLTFKMESARKAWENSPNVRE-----------KGSP-VTSTAPPIAT 2279
++P TT + K +P+ +E KG P +T +P
Sbjct: 1342 SPKGTPTLPATT--------PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
Query: 2280 GVSSSASGPSTANYNSFSSASMPQIPVA---------------SVTPTA-------SLSG 2317
+ S P++ S P PV +VTP + S
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
Query: 2318 AGTYTTSSLSTKSTTTSDPPNICK-VKPQQLQTSSLPSASHFSQLSC-MPSLIAQQQQNP 2375
G T SS + PP+ + P+Q+ TSS P + + P+L A +P
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
Query: 2376 QVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQP---GLSQPTSVQQIPIP 2432
+ + ++ + P T+ L ++ P +LA ++ P + P IP P
Sbjct: 1514 KEVPATPSSRRDP--IAPTATLL----SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 2433 IYAP 2436
AP
Sbjct: 1568 KEAP 1571
Score = 69.7 bits (169), Expect = 4e-11
Identities = 157/697 (22%), Positives = 237/697 (34%), Gaps = 117/697 (16%)
Query: 1753 PLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASP------- 1805
P+ T ++P +A + P P +T AP+ LAP + S P P+ P
Sbjct: 689 PVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPK-SVPSPSLPPAGTPPG 747
Query: 1806 ------------LAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPAS- 1852
LAPV++S + + SA A + + A +P+P+ SVS
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807
Query: 1853 -------------VTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPT 1899
+ L+S P+ AS L S + SPA P P APT
Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG-SKDSPATTHSPTPPSPKGAPT 866
Query: 1900 AS--VPLAPASASAP---APAPTPVSAP----NPAPPAPAQ------TQAQTHKPVQNPL 1944
S PL+P + P P P+ V+ P PA PAP Q T + K P
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 1945 QTTSQSSKQP-----PPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAP- 1998
+S P PP+ PS P G S K TP + + + +P
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPS---PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983
Query: 1999 ----PAVLNDISKKLGPISP-----PQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEI 2049
P S K GP +P P PP+V+ P S + P +GA S
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP-PSPKGSPAATPFPKGA-----STPPA 1037
Query: 2050 GTDTIQFGAPAS----NGNENEVVPVL-------SEKSADKIPEPKEQRQKQPRAGPIKA 2098
T G+PA+ G L + S P P P+ GP A
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP--A 1095
Query: 2099 QKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQE--------KPSPATVRST 2150
P +P+ P P G + ++ P + K +P T +T
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155
Query: 2151 DPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNT---VATNNTK 2207
P + S + G TTP+++ P+ +AT + K
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 2208 MEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKG 2267
T P P PK S PTT + T + K +P +
Sbjct: 1216 GAPTTPAATP-----PSPKGGLATPS---PKGAPTTPAAT---PPSPKGGPATPPPKGAP 1264
Query: 2268 SPVTSTAPPIATGVSS----SASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTT 2323
+P +T P + G+++ A P+ S P + TP A+ + +
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 2324 SSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQ 2360
+ K T PP + P+ T +LP+ + S+
Sbjct: 1325 GTPPPKGAPT--PPAVTPPSPK--GTPTLPATTPSSK 1357
Score = 57.4 bits (137), Expect = 2e-07
Identities = 141/644 (21%), Positives = 210/644 (32%), Gaps = 84/644 (13%)
Query: 1735 TGIQQAQSSASVPPLASAPLPPSTSAS--------VPASTSAPLPATLTPVPASTSAPVP 1786
+G +S S+ P S L S +A+ +P S+ P +T +AP
Sbjct: 396 SGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT 455
Query: 1787 ASTLAPVLASTSAPVPASPLAPVSASASVSASV-PASTSAAAITSSSAPASAPAPTP--- 1842
+A ++ + P S + P S +A V A V P S T+ P S P P P
Sbjct: 456 TFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDL 515
Query: 1843 ------ILASVSTPASV-TILAS-ASIPILASALASTSAPTPAPAASSPAAPVITAPTIP 1894
+L T + T+ AS P + T+ P AAP +P+
Sbjct: 516 KNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPK-NSPSFQ 574
Query: 1895 ASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQP 1954
+++ + +PL+P + A P+ PA + +PL S +S
Sbjct: 575 STSSSPEIPLSPEATLAKKSLGEPLPIGKPA------------SSMTSPLGVNSSASVIK 622
Query: 1955 PPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISP 2014
S P + P S+ TP + E D P S SP
Sbjct: 623 TDSYAGPDSAGP------LLKSSLITP-TVAAFPLESADPAGVAPTTAKGTSTYTTTASP 675
Query: 2015 PQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSE 2074
+VS AP + K G + L + T P + +N P+ +
Sbjct: 676 FLEGTVSL----------APKNHPVKEGTLTTLPL-VPTASENCPVAPSPQNTCAPLATL 724
Query: 2075 KSADKIPEPKEQRQKQPRAGPIKAQKLPDLS------PVEN--KEHKPGPIGKE--RSLK 2124
A +IP+ P P +K+ +S PV + KE G S K
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
Query: 2125 NRKVKDAQQVEPEG-----QEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEY 2179
A P G Q K P S P T + E + S +
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ 844
Query: 2180 GTNAKESVTDYTTPSS----SLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSS 2235
G+ + T TP S P+ V + K P P+ + LP +
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP----FPKEGP 900
Query: 2236 LTSVPPTTFSLTFKMESARKAWEN--SPNVREKGSPVTSTAPPIATGVSSSASGPSTANY 2293
T P +L+ S +KA + SP + PP AT S GP+T
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT-PPSPKGGPATP-- 957
Query: 2294 NSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPP 2337
S P P A TP + G T + T T P
Sbjct: 958 ---SPKWAPTPPAA--TPPSPKGGPATPSPKGAPTPPAATPPSP 996
Score = 45.4 bits (106), Expect = 8e-04
Identities = 106/519 (20%), Positives = 157/519 (30%), Gaps = 58/519 (11%)
Query: 697 PQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDP-RWLMMQSYMDPRMMSGRPAM 755
P P P PPP P P + P + + + P G PA
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 756 DIP---PIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPY 812
P P P PP P +GSP + + A++ P+ G+
Sbjct: 1304 SPPKGAPTPPAATPPSP-------KGSPGTPPP----KGAPTPPAVTPPSPK---GTPTL 1349
Query: 813 PHAEPQQA---TTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEA 869
P P TTP + E P + + S + PK D +S A
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD---PTSPA 1406
Query: 870 QVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGS 929
+ ++ A P +S + SA + P+ S +
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT 1466
Query: 930 NHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKS 989
P + EP A TS P P I SS P++V + S
Sbjct: 1467 LPAVTPPSPK-EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS----PKEVPATPS 1521
Query: 990 ETRWGPRPSSNR-----------REEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEK 1038
R P++ +E + + P K P + KE KE
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581
Query: 1039 AEKVTEKVVVKPEKTEKKDLPPPPPPPQP-PAPIQPQSVPP-----PIQPEAEKFPSTET 1092
VT ++ +PP P P AP P PP P P + P++
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641
Query: 1093 ATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPR 1152
T PS + P P S A TV Q + P K ++ V+ P
Sbjct: 1642 VT----PSSLKDSPTSPASVTCKMGA--TVPQASKGLPAKKGPTALKE------VLVAPA 1689
Query: 1153 PDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRG 1191
P+S P + + P+T A PD + +G
Sbjct: 1690 PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Score = 36.2 bits (82), Expect = 0.47
Identities = 96/450 (21%), Positives = 152/450 (33%), Gaps = 84/450 (18%)
Query: 697 PQTVPSQPSS-------STVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMM 749
P+ P+ PSS + PP P P P P+ +A+ P+
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEP------PAPKQVATSS------------SPKKA 1493
Query: 750 SGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGS 809
PA P P +IP P ++ +P+S + IA +A +S P L
Sbjct: 1494 PATPAPMGAPTLPAVIPSSP----KEVPATPSSRR--DPIAPTAT--LLSKKTPATL--- 1542
Query: 810 DPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEA 869
P++A P A P ++ A ++ A S + + P A A
Sbjct: 1543 ------APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE---ASSPPAVTPSTYKGA 1593
Query: 870 QVQKFLSRSVEDVRPHHTDANNQSACFEAPDQK--TLSAPQEERISAVESQPSRKRSVSH 927
K L P +A A +K AP+ S + S K S +
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653
Query: 928 GSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKS 987
++ T K + S G+P KE + P P+ I + P+ S
Sbjct: 1654 PASVTCKMGATVPQASKGLPAKKGPTA-LKEVLVAPA--PESTPIITAPTRKGPQTKKSS 1710
Query: 988 KSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEK------ 1041
+ P PS+ + P+ P P+L K+ + K K+ + K
Sbjct: 1711 ATSPPICPDPSAKNGSK---GPLSTVAPA--PLLPVQKDSSKTAKGKDASHSPKGPLAPP 1765
Query: 1042 -----------VTEKVVVKPEKTEKKDLPPPPPP-PQPPAPIQPQSVPPPIQPEAEKFPS 1089
EKV+ KPE P PP P P+P+ P P ++F
Sbjct: 1766 ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV-------PTLPPKQQFLP 1818
Query: 1090 TETATLAQKPSQDTEKPLEPVSTVQVEPAV 1119
+ + + PS KPL P ++ P +
Sbjct: 1819 SSPGLVLESPS----KPLAPADEDELLPLI 1844
Score = 32.7 bits (73), Expect = 5.2
Identities = 65/255 (25%), Positives = 86/255 (33%), Gaps = 40/255 (15%)
Query: 54 MPPPANLPSLKA-----ENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPPAQPKPGV 108
MPP A PS K +KG P G + TP P PK G+
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 109 AAPPEVAPAPKSWASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKEKETNDDNYG--P 166
A PP AP + A+ +G G+ S + P+ AA K G
Sbjct: 1164 ATPPPKG-APTTPAATPPSPKG-GLATPS--PKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
Query: 167 GPSLRPPNVACWRDGGKAAGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPP 226
P+ PP+ GG A SP + P +T + + + A PP
Sbjct: 1220 TPAATPPS----PKGGLATPSPKGA------PTTPAATPPSPKGGP--ATPPPKGAPTPP 1267
Query: 227 QAKLNGQQAALASQYRAMMPPYMFQQYPRMTYP--PLHGPMRFPPSLSET--------NK 276
A + LA+ PP+ P + P P GP PP + T K
Sbjct: 1268 AATPPSLKGGLAT------PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK 1321
Query: 277 GLRGRGPPPSWASEP 291
G G PPP A P
Sbjct: 1322 GSPGT-PPPKGAPTP 1335
Score = 32.0 bits (71), Expect = 8.9
Identities = 36/148 (24%), Positives = 50/148 (33%), Gaps = 32/148 (21%)
Query: 697 PQTVPSQPSSSTVPPP----PHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR 752
P+ +P+ PS P P P P P P P+W P G
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATP----------SPKWAPTPPAATPPSPKGG 976
Query: 753 PAMDIP---PIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGS 809
PA P P P PP P +G P + + A++ P+ +
Sbjct: 977 PATPSPKGAPTPPAATPPSP-------KGGPATPSP----KGAPTPPAVTPPSPKGSPAA 1025
Query: 810 DPYPHAEPQQATTPKATEEPEDVRSEAA 837
P+ P+ A+TP A P S AA
Sbjct: 1026 TPF----PKGASTPPAATPPSPKGSPAA 1049
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 105 bits (261), Expect = 8e-22
Identities = 88/414 (21%), Positives = 199/414 (48%), Gaps = 29/414 (7%)
Query: 323 QMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQ 382
Q E + + + +E+ K E++ + E +K+ E T + Q
Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
Query: 383 PSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADED 442
+ + + Q+R LP + L +Q +++ + ++++ D++
Sbjct: 417 KQEENMWEQEEKEWQQQR-----LPEQKEKLWEQEKMQEQEEKI-----WEQEEKIRDQE 466
Query: 443 EIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE------ 496
E+W Q ++ + + + +EE+ R +EQ+ E++ DE+L E
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
Query: 497 KQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556
K+ +E + RE +K +E+EK+ ++E+ RE+ER ++RE++ +E+E+ +EQE++ + +
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
Query: 557 KERKQEKEKELERQKEKEKEL--------QKMKEQEKECELEKEREKL---EEKIEPREP 605
+E+ +E+E+++ Q+EK +E +KM EQE+E +++++ E + EEK++ +E
Sbjct: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 606 NLEPMVEK-QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYF 664
+ EK +E E ++EE + +++ R ++E E E + R +
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
Query: 665 KQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVP-PPPHRPL 717
++ + QE+M++++ + + Q+ + + +P + P PP + L
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVL 760
Score = 99.4 bits (246), Expect = 5e-20
Identities = 124/636 (19%), Positives = 261/636 (41%), Gaps = 99/636 (15%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRRE--------------EEERRMEEQRKAA 480
K++ A+ E + ++SEI V+ +++ E +EE +E+
Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKE--------REREKELEKEQEQEREKERE 532
+K+++ +EK+ E++ +E + RE+E++ RE+EKEL +++++ RE+++
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305
Query: 533 KDRERQ-QEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEK 591
+++E Q QE+E+++ +++EK RE E++ +++E+ E++K+ ++ QKM++QE+ + +
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE--RMWE 363
Query: 592 EREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPES 651
+ E+L EK E R E M E++E +EEE + R+ R E+E
Sbjct: 364 QDERLREK-EERMREQEKMWEQEEK----MQEEERIREREKKMREEEET----------- 407
Query: 652 GSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPP 711
+ + Q+Q+E M +Q+ ++ QQQ + P
Sbjct: 408 ----------------MREQEEKMQKQEENMWEQEEKEWQQQRL---------------P 436
Query: 712 PPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAM-----DIPPIHPGMIP 766
L++ + Q + W + D M G+ + M
Sbjct: 437 EQKEKLWEQEKMQEQE------EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 767 PKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKAT 826
+ MR DQ + + E R+ + E + +W + E + K T
Sbjct: 491 QEEKMR-DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 827 EEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHH 886
+ E+ E +E+ E E K E Q +K + +
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 887 TDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGI 946
+ +E ++ + +E E ++ + ++ +E+ E +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 947 PKVTSRCIDSKEPIERPEEKPK-KEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEV 1005
+ + +E ++ EEK + +E +R E EK++ + E WG +EE+
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMRGQE----EKMW-GQEEKMWGQEEKMWGQEEM 724
Query: 1006 NDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEK 1041
++ R +RD KE+ ++R + E+ +
Sbjct: 725 REKEER---------IRDQKEKMQERLPEHEERCSE 751
Score = 99.4 bits (246), Expect = 5e-20
Identities = 129/646 (19%), Positives = 261/646 (40%), Gaps = 132/646 (20%)
Query: 433 PSKQQVADEDEIWKQR---RRQQSEISAAVE---RARKRREEEERRMEEQRKAACAEKLK 486
P Q ++E+W+Q R Q+ +I E R +R E+E +M EQ EK++
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE-----EKMR 279
Query: 487 RLDEKLGILEKQPSPEEIREREREKEREREKELEKEQE-----QEREKEREKDRERQQEK 541
R +++L EK+ +E RE++K RE+E+++++++E +E+ +E+E+ RQ+E+
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Query: 542 EKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIE 601
E EK+ +Q + +++++ ++ ER +EKE ++M+EQEK E E++ ++ EE+I
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKE---ERMREQEKMWEQEEKMQE-EERIR 395
Query: 602 PREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLS 661
RE +K E +E+E +Q+ N E+E
Sbjct: 396 ERE-------KKMREEEETMREQEEKMQKQEENMWEQEE--------------------- 427
Query: 662 GYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPM 721
K++Q+ R Q+E++ +Q+ Q+Q++ +
Sbjct: 428 ---KEWQQQ---RLPEQKEKLWEQEKMQEQEEKI-------------------------- 455
Query: 722 QPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPN 781
W + D M G+ K + R+++M +
Sbjct: 456 ---------------WEQEEKIRDQEEMWGQ--------------EKKMWRQEKMREQED 486
Query: 782 SSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQE 841
E R ++ + E RM W D + ++ K + E+ E QE
Sbjct: 487 QMWEQEEKMRD-QEQKMWDQEERM-WEQDERLREKEERMREQKKMWQQEEKMREEKKTQE 544
Query: 842 QITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQ 901
Q + E E E + +K + E +R Q ++
Sbjct: 545 QEKKTWDQEEKMRE---------EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 902 KTLSAPQEERISAVES---QPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKE 958
K QEE++ E + K + Q+ +E E + + + + +E
Sbjct: 596 KMWE--QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 959 PIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKK 1018
+ EEK +++ + EK+ + + + + + E++ + + G +K
Sbjct: 654 KMREQEEKMREQ---EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 1019 PVLRDMK----EEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPP 1060
++ K EE +++E+ ++ EK+ E++ E+ + LPP
Sbjct: 711 MWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPP 756
Score = 61.6 bits (148), Expect = 1e-08
Identities = 103/566 (18%), Positives = 223/566 (39%), Gaps = 91/566 (16%)
Query: 517 KELEKEQEQEREKEREKDRERQQ------EKEKELEK-------------EQEKQREMEK 557
+EL+K+ + +EK R + E+ + E +++LE+ ++E R+ E+
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 558 ERKQEK-----EKELERQKEKEKELQ-KMKEQEKECELEKEREKLEEK-IEPREPNLEPM 610
R+QEK E+++ RQ+E+ +E + KM+EQE++ +++R + +EK + +E L
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 611 VEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKS 670
+ +E E ++EE ++ +++ R ++E E E Q R +Q +
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ------EQKMRD 356
Query: 671 LPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLAS 730
R Q E++++++ + ++Q+ + Q Q + +
Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
Query: 731 MGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIA 790
+ W + + + P+ + + E E
Sbjct: 417 KQEENMWEQEEKEWQQQRL-----------------PEQKEKLWEQEKMQEQEEKIWEQE 459
Query: 791 RSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVE 850
RD + + +W + E Q E+ E +R DQEQ + E
Sbjct: 460 EKIRDQEEMWGQEKKMWRQEKMREQEDQM------WEQEEKMR-----DQEQ--KMWDQE 506
Query: 851 HNQLEAHPKADFIRESSE-AQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQE 909
E + +RE E + QK + + E +R + +Q+ + QE
Sbjct: 507 ERMWEQDER---LREKEERMREQKKMWQQEEKMREEK----------KTQEQEKKTWDQE 553
Query: 910 ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEK--P 967
E++ E R++ + ++ +E+ E + + + + +E ++ EEK
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 968 KKEGFIRSSEGPK----------PEKVYKSKSETRWGPRPSSNRREE-VNDRPVRRSGPI 1016
++E E K E+ + + E W +EE + ++ + G
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 1017 KKPVLRDMKEEREQRKEKEGEKAEKV 1042
+K +R+ +E+ + ++EK E+ EK+
Sbjct: 674 EK--MREQEEKMQGQEEKMREQEEKM 697
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 104 bits (260), Expect = 1e-21
Identities = 97/326 (29%), Positives = 141/326 (43%), Gaps = 24/326 (7%)
Query: 1727 PRFAKKQATG--IQQAQSSASVPPLASAPLPPSTSASVPASTSA-PLPATLTPVPASTSA 1783
P + Q G + A +S+ VP L S P + VPAS A P P+ P PA S
Sbjct: 1513 PSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASL 1572
Query: 1784 PVPASTLAPVLASTSAPV-----------PASPLAPVSASASVSASVPASTSAAAITSSS 1832
PAS+ + LA+ AP+ PA PLAP+ A + P S+
Sbjct: 1573 LAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVM 1632
Query: 1833 APASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPT 1892
AP+S P T + ++ PA +LA +S + A + P+PA + AP + APT
Sbjct: 1633 APSSTPG-TSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPAL-APT 1690
Query: 1893 IPASAPTASVPLAPASASAPAPAPTPVSAP-NPAPPAPAQTQAQTHKPVQNPLQTTSQSS 1951
+ S+P+ ++ L + P P T P + P PAQT + P P QT S +
Sbjct: 1691 LGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLS-LA 1749
Query: 1952 KQPPPSIRLPSAQTPNGTDYVA---SGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKK 2008
PP + P P T +A S S+ P S TLT PA ++
Sbjct: 1750 PAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLA-- 1807
Query: 2009 LGPISPPQPPSVSAWNKPLTSFGSAP 2034
L P S Q P+ A + +++ G+AP
Sbjct: 1808 LAPAS-TQSPASQASSLVVSASGAAP 1832
Score = 102 bits (253), Expect = 7e-21
Identities = 109/313 (34%), Positives = 146/313 (46%), Gaps = 47/313 (15%)
Query: 1742 SSASVPPLASAPL--PPSTSASVPASTSAPL--PATLTPVPAST------SAPVPASTLA 1791
+S+ +P S+PL P S++ SVP S+S P+ P TL P PAS SAP+ S
Sbjct: 1411 ASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTL-PAPASAPLTIPISAPLTVSASG 1469
Query: 1792 PVLASTSAP-----VPASP----LAPVSASASVSASVPASTSAAAITSSSAPASAPAPTP 1842
P L ++ P VPA+P LAP AS S SA +A +++SS P P
Sbjct: 1470 PALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAP 1529
Query: 1843 ILASVSTPASVTILASASIPILASALAS--TSAPTPAPAASSPAAPVITA------PTIP 1894
+ V S A + + + ASALAS SAP PAPA +S AP +A P P
Sbjct: 1530 TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589
Query: 1895 ASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQT--TSQSSK 1952
+AP ++ LAP + AP AP PV AP+P AP +QT PV P T TS +S
Sbjct: 1590 MAAPQTAI-LAP--SPAPPLAPLPVLAPSPG-AAPVLASSQTPVPVMAPSSTPGTSLASA 1645
Query: 1953 QPPPSIRLPSAQTPNGTDYVASGKS-IQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGP 2011
P P+ A + T A S + +P S TL A+ ++ LG
Sbjct: 1646 SPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTL------------ALAPALAPTLGG 1693
Query: 2012 ISPPQPPSVSAWN 2024
SP Q S+ N
Sbjct: 1694 SSPSQTLSLGTGN 1706
Score = 97.4 bits (241), Expect = 2e-19
Identities = 151/600 (25%), Positives = 221/600 (36%), Gaps = 119/600 (19%)
Query: 1746 VPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASP 1805
VPPLA AP PPS+ LPA L P P T +P TL A P P
Sbjct: 1324 VPPLAPAPRPPSSG----------LPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRP 1373
Query: 1806 LAPV--SASASVSASVPASTSAAAITSSS---------APASAPAPTPILASVSTPASVT 1854
L + S S VSAS P AA +T SS PAS+P P P + +++P S T
Sbjct: 1374 LLKLVHSPSPEVSASAPG---AAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSST 1430
Query: 1855 ILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAP----TASVPLAPASAS 1910
+ S+P+ +S S PAPA++ P+ T+ AS P + + PLAP +
Sbjct: 1431 V----SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPA 1486
Query: 1911 APAPAPTPVSAPNPA-PPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLP---SAQTP 1966
AP P P AP+ A P A A T P + QT P S +P S P
Sbjct: 1487 APGP---PSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP 1543
Query: 1967 NGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLND-ISKKLGPISPPQ----PPSVS 2021
+ + ++ +P A + +AP + + ++ L P++ PQ PS +
Sbjct: 1544 ACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPA 1603
Query: 2022 AWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIP 2081
PL +P G L + AP+S P S SA +P
Sbjct: 1604 PPLAPLPVLAPSP-------GAAPVLASSQTPVPVMAPSS-------TPGTSLASASPVP 1649
Query: 2082 EPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEK 2141
P P L+P + P P+
Sbjct: 1650 AP-----------------TPVLAPSSTQTMLPAPV------------------------ 1668
Query: 2142 PSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKE----SVTDYTTPSSSL 2197
PSP P +T+ ++ +G + GT + + T TP+SSL
Sbjct: 1669 PSPL----PSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSL 1724
Query: 2198 PNTVATNNTKMEDTLVNNVPL--PNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESAR- 2254
T A +L PL TL L + +S + P T +L SA
Sbjct: 1725 VPTPAQTL-----SLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASL 1779
Query: 2255 KAWENSPNVREKGSPVTSTAP----PIATGVSSSASGPSTANYNSFSSASMPQIPVASVT 2310
A + + +PV + P +A +S+ S S A+ S++ +PV V+
Sbjct: 1780 LAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVS 1839
Score = 89.4 bits (220), Expect = 5e-17
Identities = 245/1021 (23%), Positives = 365/1021 (35%), Gaps = 226/1021 (22%)
Query: 1753 PLPPSTSASV-----PASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLA 1807
P+P +V P + P+P P P ++ P P P + S V ASP
Sbjct: 1000 PVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPV--PQVLPASLMVSASPAG 1057
Query: 1808 PVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASA 1867
P AS P S S P P+P +L+ S P + T+ + P
Sbjct: 1058 PPLIPASRPPG-PVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRL 1116
Query: 1868 LASTSAPTPAPAASSPAAPVITAPTI---PASAPTASVPLAPASASA-PAPAPTP---VS 1920
+P P P +SS P+ P PA+A T S A A+ +A PAP P P +
Sbjct: 1117 -----SPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLIL 1171
Query: 1921 APNPAPPAPA-------QTQAQTHKPVQN-----PLQTTSQSSKQPPPSIRLPSAQTPNG 1968
+P+ P+ Q + +PV N PL Q +K + L AQ
Sbjct: 1172 SPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNK-----LTLTGAQVRQL 1226
Query: 1969 TDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLT 2028
V + +Q H ++A + ++ PA + + + + P P P SV
Sbjct: 1227 A--VGQPRPLQRNVVH-LVSAGGQHHLISQPAHV-ALIQAVAPTPGPTPVSV-------- 1274
Query: 2029 SFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQ 2088
PSS + +GL + Q P + N VV ++ ++
Sbjct: 1275 ----LPSSTPSTTPAPTGLSLPLAANQ--VPPTMVNNTGVVKIVVRQA------------ 1316
Query: 2089 KQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVR 2148
PR G +P L+P +P G L R + P P+ T R
Sbjct: 1317 --PRDG---LTPVPPLAPAP----RPPSSGLPAVLNPRPT-----LTPGRLPTPTLGTAR 1362
Query: 2149 STDPVTT---KETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNN 2205
+ P T K V S E+ SA A +++ SSLP +
Sbjct: 1363 APMPTPTLVRPLLKLVHSPSPEV-------SASAPGAAPLTISSPLHVPSSLPGPAS--- 1412
Query: 2206 TKMEDTLVNNVPLPNTLPL--PKRETIQ--QSSSLTSVPPTTFSLTFKMESARKAWENSP 2261
+ +P+PN+ PL P T+ SSSL PTT
Sbjct: 1413 --------SPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTL----------------- 1447
Query: 2262 NVREKGSPVTSTAP---PIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGA 2318
P ++AP PI+ ++ SASGP A S + P +P A P+ + SGA
Sbjct: 1448 -------PAPASAPLTIPISAPLTVSASGP--ALLTSVTPPLAPVVPAAPGPPSLAPSGA 1498
Query: 2319 ---------GTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLI- 2368
G T SLS+ T P + + P +S +P + +C P L+
Sbjct: 1499 SPSASALTLGLATAPSLSSSQT----PGHPLLLAP---TSSHVPGLNSTVAPACSPVLVP 1551
Query: 2369 AQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQ 2428
A +P A AQ + S LAP + Q P + P +
Sbjct: 1552 ASALASPFPSAPNPAPAQ-ASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLA--- 1607
Query: 2429 IPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGT 2488
P+P+ AP S GA P ++ +Q + P + + +SL+ S V + T
Sbjct: 1608 -PLPVLAP---------SPGAAPVLASSQ-----TPVPVMAPSSTPGTSLASASPVPAPT 1652
Query: 2489 AIHNFPTVQHQELAKAQSGLAFQQTSNTQPI-PILYEHQLGQASGLGGSQLIDTHLLQAR 2547
+ + Q A S L ++ T + P L A LGGS
Sbjct: 1653 PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPAL-------APTLGGS----------- 1694
Query: 2548 ANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSL---PNFGSTGQPLI 2604
+ +Q +L +G Q P T + + S VP PA LSL P G T Q L
Sbjct: 1695 -SPSQTLSLGTGNPQGPFPTQTLSLTPASS-----LVPTPAQTLSLAPGPPLGPT-QTLS 1747
Query: 2605 ALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFG 2664
P PPL +P A PA L PA + S++A +
Sbjct: 1748 LAP---APPLAPASPVGPA-----PAHTLT----LAPASSSASLLAPASVQT-------- 1787
Query: 2665 SGIDIKPGTPPIAGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQPF 2724
+ + P P G + T + A++ SP SQ+S S+V +AP V M
Sbjct: 1788 --LTLSPAPVPTLGPAAAQTLALAPASTQSPASQAS---SLVVSAS-GAAPLPVTMVSRL 1841
Query: 2725 P 2725
P
Sbjct: 1842 P 1842
Score = 77.4 bits (189), Expect = 2e-13
Identities = 74/240 (30%), Positives = 103/240 (42%), Gaps = 24/240 (10%)
Query: 1721 QTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPAS 1780
QT+ L P A A A S + P LAS+ P A P+ST A+ +PVPA
Sbjct: 1594 QTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMA--PSSTPGTSLASASPVPAP 1651
Query: 1781 TSAPVPASTLAPVLASTSAPVPASPLAPVSASA-SVSASVPASTSAAAITSSSAPASAPA 1839
T P+ST + A +P+P+ A A +++ ++ S+ + ++ + P
Sbjct: 1652 TPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711
Query: 1840 PTPIL----ASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPA 1895
PT L AS P L+ A P L + AP P A +SP P
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGP--------- 1762
Query: 1896 SAPTASVPLAPASAS----APAPAPTPVSAPNPAP---PAPAQTQAQTHKPVQNPLQTTS 1948
AP ++ LAPAS+S APA T +P P P PA AQT A Q+P S
Sbjct: 1763 -APAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQAS 1821
Score = 77.0 bits (188), Expect = 2e-13
Identities = 93/333 (27%), Positives = 121/333 (36%), Gaps = 45/333 (13%)
Query: 1727 PRFAKKQATGIQQAQSSASVPPLASA-PLPPSTSASVPASTSAPLPATLT---PVPASTS 1782
P A Q A SS LASA P+P T P+ST LPA + P PAST
Sbjct: 1620 PVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQ 1679
Query: 1783 APVPASTLAPVLASTSAP---------------------VPASPLAPVSASASVSASVPA 1821
A LAP L +S PAS L P A A P
Sbjct: 1680 TLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPP 1739
Query: 1822 STSAAAITSSSAPASAPA----PTPILASVSTPASVTILASASIPILASALASTSAPTPA 1877
++ + AP APA P P PAS +SAS+ AS T +P P
Sbjct: 1740 LGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS----SSASLLAPASVQTLTLSPAPV 1795
Query: 1878 PAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTH 1937
P AA + +P + SAS AP P + + P T
Sbjct: 1796 PTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRS 1855
Query: 1938 KPVQNPLQTTS----QSSKQPPPSIRLP----SAQTPNGTDYVASGKSI-QTPQSHGTLT 1988
P P TS + +QPPP R P S + + I Q ++HG L
Sbjct: 1856 GPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGAL- 1914
Query: 1989 AELWDNKVAPPAVL-NDISKKLGPISP-PQPPS 2019
A ++ +V L ++ +GP SP P P+
Sbjct: 1915 APVYGTEVLDFCTLPQPVASPIGPRSPGPSHPT 1947
Score = 70.1 bits (170), Expect = 3e-11
Identities = 172/743 (23%), Positives = 256/743 (34%), Gaps = 117/743 (15%)
Query: 1731 KKQATGIQQAQSSASVP-PLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAST 1789
K TG Q Q + P PL + ++ S P L A T P P S
Sbjct: 1215 KLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSV 1274
Query: 1790 LAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVST 1849
L ST+ P P P++A+ V ++ +T I AP P P LA
Sbjct: 1275 LPSSTPSTT-PAPTGLSLPLAAN-QVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLA---- 1328
Query: 1850 PASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTI-PASAPTASVPLAPAS 1908
P P P +S A + PT+ P PT P
Sbjct: 1329 ------------------------PAPRPPSSGLPAVLNPRPTLTPGRLPT------PTL 1358
Query: 1909 ASAPAPAPTPV-------SAPNPAPPAPAQTQAQTHKPVQNPLQTTSQ-----SSKQP-P 1955
+A AP PTP +P+P A + +PL S SS P P
Sbjct: 1359 GTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIP 1418
Query: 1956 PSIRLPSAQTPNGTDYVASGKSIQTPQS-HGTLTAELWDNKVAP-------PAVLNDISK 2007
S L S + + ++S I P + +A L AP PA+L ++
Sbjct: 1419 NSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTP 1478
Query: 2008 KLGPISP--PQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNE 2065
L P+ P P PPS L G++PS+ S L +G T AP+ + ++
Sbjct: 1479 PLAPVVPAAPGPPS-------LAPSGASPSA--------SALTLGLAT----APSLSSSQ 1519
Query: 2066 NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN 2125
P+L ++ +P P P+ SP + P P + SL
Sbjct: 1520 TPGHPLLLAPTSSHVPGLNS--TVAPACSPVLVPASALASPFPS---APNPAPAQASLLA 1574
Query: 2126 RKVKDAQQVEPEGQEKPSPAT-VRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAK 2184
+Q + +P T + + P V S +++ S A
Sbjct: 1575 PASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP 1634
Query: 2185 ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPT-- 2242
S T T+ +S+ P T T +P P PLP + Q + ++ PT
Sbjct: 1635 SS-TPGTSLASASPVPAPTPVLAPSST-QTMLPAPVPSPLPSPASTQTLALAPALAPTLG 1692
Query: 2243 --TFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSAS 2300
+ S T + + P +P +S P A + S A GP + S A
Sbjct: 1693 GSSPSQTLSLGTGNPQGP-FPTQTLSLTPASSLVPTPAQTL-SLAPGPPLGPTQTLSLAP 1750
Query: 2301 MPQIPVAS---VTPTASLSGAGTYTTSSL---STKSTTTSDPPNICKVKPQQLQTSSLPS 2354
P + AS P +L+ A +++SL ++ T T P + + P QT +L
Sbjct: 1751 APPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAP 1810
Query: 2355 ASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYM-------DTSHLFNTQHARLAP 2407
AS S S SL+ VS S AA +P + D + +P
Sbjct: 1811 ASTQSPASQASSLV----------VSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSP 1860
Query: 2408 PSLAQQQGFQPGLSQPTSVQQIP 2430
PS A G QP + P
Sbjct: 1861 PSTATSFGGPRPRRQPPPPPRSP 1883
Score = 68.2 bits (165), Expect = 1e-10
Identities = 103/381 (27%), Positives = 140/381 (36%), Gaps = 52/381 (13%)
Query: 1743 SASVPPLAS-----APLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLAST 1797
S + PP S P P PAS A +PA L PVP S APVP S P+ T
Sbjct: 2422 STTTPPRCSPARERVPRPAPRPRPTPASAPAAIPA-LVPVPVS--APVPISAPNPI---T 2475
Query: 1798 SAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILA 1857
PV P +P S S PA T A T P A P P + TP+S +L
Sbjct: 2476 ILPVHILP-SPPPPSQIPPCSSPACTPPPACT----PPPAHTPPPAQTCLVTPSSPLLLG 2530
Query: 1858 SASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPT 1917
S+PI AS T P P A + A +P S + A +
Sbjct: 2531 PPSVPISASV-------TNLPLGLRPEAEL-----------CAQALASPESLELASVASS 2572
Query: 1918 PVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKS 1977
S+ + PP A PV + + S+ PS+ L + PNG + A
Sbjct: 2573 ETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSA----PSLTLEAGSIPNGQEQEA---- 2624
Query: 1978 IQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS----PPQPPSVSAWNKPLTSFGSA 2033
+ GT L + + P V +L P + P Q P + +
Sbjct: 2625 --PDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKT 2682
Query: 2034 PSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSAD-KIPEPKEQRQKQPR 2092
P+S K + E+ + A +S + P SAD +I R QP
Sbjct: 2683 PTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQP- 2741
Query: 2093 AGPIKAQKLPD--LSPVENKE 2111
GP +KLP ++ VE KE
Sbjct: 2742 PGPKVLRKLPGRLVTVVEEKE 2762
Score = 64.3 bits (155), Expect = 2e-09
Identities = 197/849 (23%), Positives = 292/849 (34%), Gaps = 127/849 (14%)
Query: 1742 SSASVPPLASAPLPPSTSASVPA---STSAP--LPATLTPVPASTSAPVPASTLAPVLAS 1796
+S + PPL A PP P S S P LP+ L + ++ P P +L P +
Sbjct: 1053 ASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKP---T 1109
Query: 1797 TSAPVPASPLAPVSASASV-------------SASVPASTSAAAITSSSAPASAPAPTPI 1843
APV SP P +S+ + +A+ ST+ A T+++ PA PAP +
Sbjct: 1110 PPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRL 1169
Query: 1844 LASVSTPA--------SVTILASASIPILASA--------------LASTSAPTPAPAAS 1881
+ S A S+ LAS + +A+A L T A A
Sbjct: 1170 ILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVG 1229
Query: 1882 SP---AAPVITAPTIPASAPTASVP--LAPASASAPAPAPTPVSAPNPAPPAPAQTQAQT 1936
P V+ + S P +A A AP P PTPVS P+ T + T
Sbjct: 1230 QPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSV------LPSSTPSTT 1283
Query: 1937 HKPVQNPLQTTSQSSKQPPPS-------IRLPSAQTP-NGTDYVASGKSIQTPQSHGTLT 1988
P L ++ Q PP+ +++ Q P +G V P S G L
Sbjct: 1284 PAPTGLSLPL---AANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSG-LP 1339
Query: 1989 AELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLE 2048
A L P L + LG P P +PL +PS E + + +
Sbjct: 1340 AVLNPRPTLTPGRLP--TPTLGTARAPMPTPTLV--RPLLKLVHSPSPEVSASAPGA--- 1392
Query: 2049 IGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLS--- 2105
AP + + V L ++ +P P P A P+ + LS
Sbjct: 1393 ---------APLTISSPLHVPSSLPGPASSPMPIP----NSSPLASPVSSTVSVPLSSSL 1439
Query: 2106 PVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAV--SE 2163
P+ P P ++ + V G PA + S P A
Sbjct: 1440 PISVPTTLPAPASAPLTI---PISAPLTVSASG-----PALLTSVTPPLAPVVPAAPGPP 1491
Query: 2164 MSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLP 2223
G S S+ G S++ TP P +A ++ + P + +
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGH--PLLLAPTSSHVPGLNSTVAPACSPVL 1549
Query: 2224 LPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVT-----STAPPIA 2278
+P S + P SL SA +A + + +P T S APP+A
Sbjct: 1550 VPASALASPFPSAPNPAPAQASLLAPASSASQAL--ATPLAPMAAPQTAILAPSPAPPLA 1607
Query: 2279 TGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTY--TTSSLSTKSTTTSDP 2336
+ A P A + S +P + S TP SL+ A T L+ ST T P
Sbjct: 1608 P-LPVLAPSPGAAPVLASSQTPVP-VMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLP 1665
Query: 2337 PNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSH 2396
+ S LPS + L+ P+L A + S P T
Sbjct: 1666 APV---------PSPLPSPASTQTLALAPAL-APTLGGSSPSQTLSLGTGNPQGPFPTQT 1715
Query: 2397 LFNTQHARLAPPSLAQQQGFQPG--LSQPTSVQQIPIPIYAPLQGQHQAQL-SLGAGPAV 2453
L T + L P+ AQ PG L ++ P P AP A +L PA
Sbjct: 1716 LSLTPASSLV-PTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS 1774
Query: 2454 SQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLS-GTAIHNFPTVQHQELAKAQSGLAFQQ 2512
S A L +S+Q PA + + + L+ A P Q L + SG A
Sbjct: 1775 SSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLP 1834
Query: 2513 TSNTQPIPI 2521
+ +P+
Sbjct: 1835 VTMVSRLPV 1843
Score = 50.1 bits (118), Expect = 3e-05
Identities = 52/284 (18%), Positives = 111/284 (39%), Gaps = 55/284 (19%)
Query: 337 DDEQGSNSPKENNSED-----QGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYG 391
DDE G P+E+ ED + + E N+ + + E+ + ++P + + +P
Sbjct: 283 DDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQ 342
Query: 392 --KGPSFNQERGTSSH---------------------LPPPPKLLAQQ-----HPPPDRQ 423
+GPS + + SSH + PPP + Q+ HP D +
Sbjct: 343 LLEGPS-SPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDE 401
Query: 424 AVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAE 483
++++ DE++ + + E+ A+E + RE E E ++ A A
Sbjct: 402 EFTA------NEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAY 455
Query: 484 KLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEK 543
P + + ++ + E E E E+ ++D Q + +
Sbjct: 456 A--------------PGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVE 501
Query: 544 ELEKEQEKQREMEKERK-QEKEKELERQKEKEKELQKMKEQEKE 586
+ +++E + E+E +E E ++ ++ + Q ++E+E
Sbjct: 502 DRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEE 545
Score = 48.5 bits (114), Expect = 9e-05
Identities = 115/602 (19%), Positives = 224/602 (37%), Gaps = 63/602 (10%)
Query: 366 ETDEVSNTKSSSQIPAQPSVAKVPY--GKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQ 423
+T VS+ + S P P+ + P G G Q S L PP PPD
Sbjct: 16 QTQMVSDGMTGSN-PVSPASSSSPASSGAGGISPQHIAQDSSLDGPPG-------PPDGA 67
Query: 424 AVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAE 483
VP +A++ W++ A + K E E R+ E RK
Sbjct: 68 TVPLEGFSLSQAADLANKGPKWEKSH-------AEIAEQAKHEAEIETRIAELRKEGFWS 120
Query: 484 KLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEK 543
LKRL + + + P P+ + E+ + + +E+ +R R+ R + E+
Sbjct: 121 -LKRLPK----VPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEE 175
Query: 544 ELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPR 603
+ +KE+ +RE + + ++ + ++ ++K+ + +++ LE++R+K
Sbjct: 176 QRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKK------AL 229
Query: 604 EPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGY 663
+ +L+ +V + E + + Q S+ ++P + + S P + L
Sbjct: 230 DLHLDFIVGQTEKYSDLLSQS----LNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDDE 285
Query: 664 FKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQP 723
FQ + ++E ++ ++QQ+G + + PL + ++
Sbjct: 286 DGDFQPQ-----EDEEEDDEETIEVEEQQEG--NDAEAQRREIELLRREGELPLEELLRS 338
Query: 724 HPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPP----IHPGMIPPKPLMRRDQMEGS 779
P L P D R A + PP I P PP + +R++
Sbjct: 339 LPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKP---PPSAVTQRNKQPWH 395
Query: 780 PN-SSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAAL 838
P+ E F A D +++ L G E A ++ E L
Sbjct: 396 PDEDDEEFTANEEEAEDEEDTIAAEEQLEG-------EVDHAMELSELAREGELSMEELL 448
Query: 839 DQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFE- 897
+Q AY+ E + + SS+ + + VE P D+++QS E
Sbjct: 449 --QQYAGAYAPGSGSSEDEDEDEVDANSSDCEPE----GPVEAEEPPQEDSSSQSDSVED 502
Query: 898 -APDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDS 956
+ D++ + +EE + S+ S + +Q DE+ + G+ + +R +
Sbjct: 503 RSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQ-ADEEEEDDDFGVEYLLARDEEQ 561
Query: 957 KE 958
E
Sbjct: 562 SE 563
Score = 39.7 bits (91), Expect = 0.043
Identities = 76/346 (21%), Positives = 118/346 (34%), Gaps = 73/346 (21%)
Query: 783 SESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKAT-EEPEDVRSEAALDQE 841
+E E I + + A ++E +D +P E ++A P A EE E A E
Sbjct: 2248 AEDEEDIRAATQAKAEQVAELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVE 2307
Query: 842 QITAAYSVEHNQLEAHPKADFIRESSEAQVQ-----KFLSRSVEDV------RPHHTDAN 890
Q+T LEA + E +A+ Q K L ++ E+V A
Sbjct: 2308 QLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAG 2367
Query: 891 NQSACFEA--PDQKTLSAPQEERISAVESQPSR-KRSVSHGSNHTQKPDEQRSEPSAGIP 947
++S+C +++ A ER S+ R R+ + G+NHT ++ + P
Sbjct: 2368 DESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPP 2427
Query: 948 KVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVND 1007
RC ++E + RP +P+ P P+S
Sbjct: 2428 ----RCSPARERVPRPAPRPR--------------------------PTPASAPAAIPAL 2457
Query: 1008 RPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQP 1067
PV S P+ P+ + + P LP PPPP Q
Sbjct: 2458 VPVPVSAPV--PI--------------------SAPNPITILPVHI----LPSPPPPSQI 2491
Query: 1068 PAPIQPQSVPPP--IQPEAEKFPSTETATLAQKPSQDTEKPLEPVS 1111
P P PPP P A P +T + P P+S
Sbjct: 2492 PPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPIS 2537
Score = 39.3 bits (90), Expect = 0.056
Identities = 138/683 (20%), Positives = 234/683 (34%), Gaps = 114/683 (16%)
Query: 466 REEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQ 525
RE + +EE ++ + +E + + + + E E++ + + EQ
Sbjct: 2207 RELFDMPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVA 2266
Query: 526 EREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEK 585
E + E D E E E + + EM + +QE +E+ E+ K E
Sbjct: 2267 ELAEFNENDGFPAGEGE-EAGRPGAEDEEMSRA-EQEIAALVEQLTPIERYAMKFLEASL 2324
Query: 586 ECELEKEREKLEEKIEPREPNLEPMVE------KQESENSCNKEEEPVFTRQDSNRSEKE 639
E +E ++ EE++E +L+ E ++E E +E T ++R K+
Sbjct: 2325 EEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKK 2384
Query: 640 A----TPVVHETEPESGSQP------RPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ 689
A P +E G++ V+S + + + PPR +E++ + +
Sbjct: 2385 AKAPERPGTRVSERLRGARAETQGANHTPVISAH-QTRSTTTPPRCSPARERVPRPAPRP 2443
Query: 690 QQQQGVLPQTVPS-QPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRM 748
+ P +P+ P + P P P P+ P H+ +
Sbjct: 2444 RPTPASAPAAIPALVPVPVSAPVPISAP--NPITILPVHI-------------------L 2482
Query: 749 MSGRPAMDIPPI-HPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLW 807
S P IPP P PP P + H A+ ++ S P +L
Sbjct: 2483 PSPPPPSQIPPCSSPACTPP------------PACTPPPAHTPPPAQTCLVTPSSPLLL- 2529
Query: 808 GSDPYPHAEPQQATTPKATEEPEDVRSEAAL--------DQEQITAAYSVEHNQLEAHPK 859
P + T P +R EA L + ++ + S E + L P
Sbjct: 2530 -------GPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPP 2582
Query: 860 ADFIRESSEAQVQKFLSRSVEDVRPHHT-----DANNQSACFEAPDQ---KTLSA-PQEE 910
D + + E + S+ P T N Q EAPD TL+ P+ E
Sbjct: 2583 KDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQ--EAPDSAEGTTLTVLPEGE 2640
Query: 911 RISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKE 970
+ S+ SN + P S+ P R + + P P+K
Sbjct: 2641 ELPLCVSE----------SNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKP 2690
Query: 971 GFIRSSEGPKPEKVYKSKSETRWGPRPS-SNRREEVNDRPVRRSG------PIKKPVLRD 1023
+ ++E P S + + GP P+ RR D +R G P VLR
Sbjct: 2691 QELVTAEVAAP-STSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRK 2749
Query: 1024 MK-------EEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSV 1076
+ EE+E + + ++ T + P +E P P P
Sbjct: 2750 LPGRLVTVVEEKELVRRRRQQRGAAST----LVPGVSETSASPGSPSVRSMSGP----ES 2801
Query: 1077 PPPIQPEAEKFPSTETATLAQKP 1099
PPI E PS+ T Q+P
Sbjct: 2802 SPPIGGPCEAAPSSSLPTPPQQP 2824
Score = 37.7 bits (86), Expect = 0.16
Identities = 46/183 (25%), Positives = 66/183 (36%), Gaps = 24/183 (13%)
Query: 1754 LPPSTSASVPASTSAPLPAT---LTPVPASTSAP------VPASTLAPVLAS--TSAPVP 1802
LPPS ++ P T LT TS+P V A AP +S TS+P
Sbjct: 2654 LPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEG 2713
Query: 1803 ASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIP 1862
SP P S + + P P P + VT++ +
Sbjct: 2714 PSPARPPRRRTSADVEIRGQ-------GTGRPGQPPGPKVLRKLPGR--LVTVVEEKELV 2764
Query: 1863 ILAS---ALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPL-APASASAPAPAPTP 1918
AST P + ++SP +P + + + P S+P P A S+S P P P
Sbjct: 2765 RRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQP 2824
Query: 1919 VSA 1921
A
Sbjct: 2825 FIA 2827
Score = 35.0 bits (79), Expect = 1.0
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 4/114 (3%)
Query: 1748 PLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLA 1807
PL S P+ P + P+P T++ S + T P S P+P +
Sbjct: 2929 PLLS-PVEKRRRGRPPKARDLPIPGTISSAGDGNSE---SRTQPPPHPSPLTPLPPLLVC 2984
Query: 1808 PVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASI 1861
P + A+ +V STS P + P+P P V S ++L S +
Sbjct: 2985 PTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGL 3038
Score = 34.3 bits (77), Expect = 1.8
Identities = 50/221 (22%), Positives = 73/221 (33%), Gaps = 20/221 (9%)
Query: 1750 ASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPV 1809
A++ L P S + S S P+ + +S P+ P A+ S+ +P P P
Sbjct: 2773 AASTLVPGVSET---SASPGSPSVRSMSGPESSPPIGG----PCEAAPSSSLPTPPQQPF 2825
Query: 1810 SASASVSASVPASTSA----AAITSSSAPASAPAPTPILASVSTPASVTILASASIPILA 1865
A + V S A+ + + PA +PA +
Sbjct: 2826 IARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTL 2885
Query: 1866 SALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPA 1925
+ + P P P A PV+ IP P L P P P +PV
Sbjct: 2886 KGKTNGADPVPGPETLIVADPVLEPQLIPGPQP-----LGPQPVHRPNPLLSPVEKRRRG 2940
Query: 1926 PPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTP 1966
P P + + S+S QPPP PS TP
Sbjct: 2941 RP-PKARDLPIPGTISSAGDGNSESRTQPPPH---PSPLTP 2977
Score = 32.3 bits (72), Expect = 6.8
Identities = 47/243 (19%), Positives = 80/243 (32%), Gaps = 37/243 (15%)
Query: 1718 GRSQTSKLPPRFAKKQATGIQQAQ---SSASVPPLASAPLPPS-------------TSAS 1761
G S+TS P + + +G + + P +S P PP T
Sbjct: 2780 GVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGG 2839
Query: 1762 VPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPA 1821
P + L A P P +P A V +P + + + + VP
Sbjct: 2840 SPENGDGALLAITPPAVKRRRGRPPKKNRSP--ADAGRGVDEAPSSTLKGKTNGADPVPG 2897
Query: 1822 STSAAAITSSSAPASAPAP-----------TPILASVSTPASVTILASASIPI---LASA 1867
+ P P P P+L+ V + +PI ++SA
Sbjct: 2898 PETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSA 2957
Query: 1868 ----LASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPN 1923
S + P P P+ +P P++ PT + +V ++ + P P + P+
Sbjct: 2958 GDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRP-PKNPPS 3016
Query: 1924 PAP 1926
P P
Sbjct: 3017 PRP 3019
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 104 bits (259), Expect = 1e-21
Identities = 70/268 (26%), Positives = 149/268 (55%), Gaps = 31/268 (11%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA--------ACAEKLKR----- 487
E+++W+Q + Q E+ K RE+EE+ E++ K EK++R
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 488 --LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKEL 545
+EK+ LE+ +E + RE E++ ++++ +++E+ +E+E+ +++E++QE+E ++
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418
Query: 546 EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREP 605
+++EK RE E E+ +E+EK++ RQ+EK E +K++E+EK E ++E + EEKI +E
Sbjct: 419 WRQEEKIREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKRQE-QEEMWRQEEKIREQE- 475
Query: 606 NLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFK 665
+ EK + K+EE V+ +++ ++E + E E + Q +
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK---IREQEEKMWRQ----------E 522
Query: 666 QFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
+ + + + Q+E++++Q+ Q+Q+
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQE 550
Score = 97.8 bits (242), Expect = 1e-19
Identities = 70/259 (27%), Positives = 144/259 (55%), Gaps = 21/259 (8%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
E+ +W++ + + E+ + K RE+EE+R EE++ E+ KR +++ + ++
Sbjct: 369 EEMMWEKEEKIR-ELEEKMHEQEKIREQEEKRQEEEK---IREQEKRQEQEAKMWRQE-- 422
Query: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME---- 556
E+IRE+E EK RE+EK++ +++E+ E+E+ ++ E++QE+E E+ +++EK RE E
Sbjct: 423 -EKIREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE-EMWRQEEKIREQEEIWR 479
Query: 557 -KERKQEKEKELERQKEKEKELQKMKEQEKEC-ELEKEREKLEEKIEPREPNLEPMVEKQ 614
KE+ E+EK +++++ ++ +KM +QE++ E E++ + EEKI +E + EK
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 615 ESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPR 674
+ +E+E Q+ E+E E E + R K+ + +
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ------KEKIREQEEK 593
Query: 675 FQRQQEQMKQQQWQQQQQQ 693
Q+E++++Q+ Q+Q+
Sbjct: 594 IWEQEEKIREQEEMMQEQE 612
Score = 95.9 bits (237), Expect = 5e-19
Identities = 82/307 (26%), Positives = 164/307 (53%), Gaps = 38/307 (12%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
++++ ++++I +Q ++Q E K RE+E+R+ +E + EK++ +EK+
Sbjct: 383 EEKMHEQEKIREQEEKRQEE--------EKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 495 LEKQP--SPEEIRE----REREKERERE---KELEKEQEQE---REKEREKDRERQQEKE 542
EK+ E+I E RE EK +E+E ++ EK +EQE R+KE+ ++E+ +++E
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
Query: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKEL-QKMKEQEKECELEKEREKLEEKIE 601
+++ +++EK + E E+ +E+E+++ RQ+EK +E +K++EQE EK RE+ EE ++
Sbjct: 495 EKVWRQEEKMHDQE-EKIREQEEKMWRQEEKIREQEEKIREQE-----EKIREQ-EEMMQ 547
Query: 602 PREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLS 661
+E + EK + + ++EE + +++ R +KE + E E + Q
Sbjct: 548 EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK---IREQEEKIWEQEEKIREQ 604
Query: 662 GYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPM 721
Q Q+ + Q+E+M +Q+ + Q+Q+ + + Q R + M
Sbjct: 605 EEMMQEQEE---KMWEQEEKMCEQEEKMQEQE----EKMRRQEEKMWEQEVRLRQQEEKM 657
Query: 722 QPHPQHL 728
Q H +HL
Sbjct: 658 QEHQEHL 664
Score = 87.0 bits (214), Expect = 2e-16
Identities = 73/288 (25%), Positives = 153/288 (53%), Gaps = 50/288 (17%)
Query: 433 PSKQQVADEDEIWKQRRRQQSEISAAVERAR-----KRREEEERRMEEQRKAACAEKLKR 487
P +Q A+ D + K+ + +++ A VE +++EE+ +E++ EK++
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318
Query: 488 LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQ--------- 538
+EK+ + E+IRE+E + R+ E EKE++ R++E ++E +
Sbjct: 319 QEEKI-----REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 539 --QEKEKELEK---EQEKQREMEKERK-----QEKEKELERQKEKEKELQKMKEQEKEC- 587
+EK +ELE+ EQEK RE E++R+ +E+EK E++ + ++ +K++EQE++
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHET 647
E EK+ + EEKI +E E EK++ + ++EE + +++ R +++ +HE
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKEK----MHEQ 487
Query: 648 EPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ---WQQQQQ 692
E + + ++Q +K Q+E++++Q+ W+Q+++
Sbjct: 488 EKIRKQEEK------VWRQEEK-----MHDQEEKIREQEEKMWRQEEK 524
Score = 84.3 bits (207), Expect = 2e-15
Identities = 47/174 (27%), Positives = 103/174 (59%), Gaps = 12/174 (6%)
Query: 441 EDEIWKQRRRQQSEISAAVERARK--------RREEEERRMEEQRKAACAEKLKRLDEKL 492
E+++W+Q + + E+ K R +EE+ R +E++ E ++ +EK+
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 493 GILEKQPSPEEIREREREKEREREKELEKEQEQEREKERE--KDRERQQEKEKELEKEQE 550
G E++ +E R+ EK RE+E+++ +++E+ RE+E + + E+ +E+E+ +++++E
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
Query: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPRE 604
K E E++ +++EK E++++ ++ +KM EQ E L ++ EK++E E E
Sbjct: 614 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ--EVRLRQQEEKMQEHQEHLE 665
Score = 80.1 bits (196), Expect = 3e-14
Identities = 69/253 (27%), Positives = 134/253 (52%), Gaps = 16/253 (6%)
Query: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKL-KRLDEKLGILEKQPSPEEIRERER 509
++SEI V+ +++ E + + +Q+ A A+ L K L L+ Q E+ R
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 510 EKERE---REKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKE 566
+++ E R++E +E E++ +++ EK RE Q+EK +E E++ +Q EM E++++ ++
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 567 LERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQES----ENSCNK 622
E EKE+++++++E E E EK RE LEEK+ +E E ++QE E +
Sbjct: 355 EEMMWEKEEKMRRLEEMMWEKE-EKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
Query: 623 EEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQK-SLPPRFQRQQEQ 681
E+E RQ+ E+E + E E + Q ++ +K RQ+E+
Sbjct: 413 EQEAKMWRQEEKIREQEEK--IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 682 MKQQQ--WQQQQQ 692
+++Q+ W+Q+++
Sbjct: 471 IREQEEIWRQKEK 483
Score = 79.0 bits (193), Expect = 6e-14
Identities = 55/173 (31%), Positives = 108/173 (62%), Gaps = 32/173 (18%)
Query: 441 EDEIWKQR---RRQQSEISAAVERARKRRE----------EEERRMEEQRKAACAEKLKR 487
E+++W+Q R Q+ +I E+ R++ E E+E +M+EQ EK++R
Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ------EKMRR 568
Query: 488 LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEK 547
+EK+ + E+IRE ++EK RE+E+++ +++E+ RE+E E QE+E+++ +
Sbjct: 569 QEEKI-----REQEEKIRE-QKEKIREQEEKIWEQEEKIREQE-----EMMQEQEEKMWE 617
Query: 548 EQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600
++EK E E E+ QE+E+++ RQ+EK E Q+++ +++E ++++ +E LE I
Sbjct: 618 QEEKMCEQE-EKMQEQEEKMRRQEEKMWE-QEVRLRQQEEKMQEHQEHLEAAI 668
Score = 74.7 bits (182), Expect = 1e-12
Identities = 67/301 (22%), Positives = 138/301 (45%), Gaps = 54/301 (17%)
Query: 445 WKQRRRQQSEISAAVERARKR--------REEEERRMEEQRKAACAEKLK----RLDEKL 492
WK + +SA + +K +E + +E R E+LK +L EKL
Sbjct: 171 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKL 230
Query: 493 GILEKQPSPEEIREREREKEREREKELEKEQE---------------------------- 524
++E + S ++ +E +++ ER K L +Q+
Sbjct: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 290
Query: 525 -----QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEK--EKEL 577
Q++E++ + E+ QE E+++++++EK RE E E+ +E+E+++ RQ+E EKE
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEE 349
Query: 578 QKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEE----EPVFTRQDS 633
+ +++E E E++ +LEE + +E + + EK + ++E E R+
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 409
Query: 634 NRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ--WQQQQ 691
R E+EA E + + ++Q +K R++E+ ++Q+ W+Q++
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 469
Query: 692 Q 692
+
Sbjct: 470 K 470
Score = 41.2 bits (95), Expect = 0.015
Identities = 117/682 (17%), Positives = 231/682 (33%), Gaps = 112/682 (16%)
Query: 402 TSSHLPPPPKLLAQQHPP-----PDRQAVPGRPGPFPSKQQ---VADEDEIWKQRRRQQS 453
T HLP P L H P P +P P +Q ++++ +
Sbjct: 17 THPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNP 76
Query: 454 EISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKER 513
+ A +K++ E C SPE+ ++ + +
Sbjct: 77 SVGTAASDTKKKKINNGTNPETTTSGGCH-----------------SPEDEQKASHQHQE 119
Query: 514 EREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQK-- 571
+ELE + R +K E + L Q +++E E + + + K
Sbjct: 120 ALRRELEAQVHTIRILTCQKT-----ELQMALYYSQHAVKQLEGEARDLISRLHDSWKFA 174
Query: 572 -EKEKELQKMKEQEKEC-----ELEKEREKL----------EEKIEPREPNLEPMVEKQE 615
E E+ L + Q+K+ EL KER+ L +E+++ + L+ ++ E
Sbjct: 175 GELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 234
Query: 616 SENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPR- 674
SE S E ++ R + A ++ + + ++ + L + Q +
Sbjct: 235 SEKS-----EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 289
Query: 675 -FQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGF 733
+ R +Q +++ W+Q+++ + + Q R + M+ + +
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM----- 344
Query: 734 DPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSA 793
W + M M + MRR + E E +
Sbjct: 345 ---WEKEEKMRRQEEM--------------MWEKEEKMRRLE-EMMWEKEEKIRELEEKM 386
Query: 794 RDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQ 853
+ + + E +Q K + E +R + +E+I Q
Sbjct: 387 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ----EEKIREQEKKMWRQ 442
Query: 854 LEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERIS 913
E + + IRE + Q Q+ + R E +R + E +E+I
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE-----------QEKIR 491
Query: 914 AVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFI 973
E + R+ H + E++ + + + + +E I EEK I
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEK------MWRQEEKIREQEEKIREQEEK------I 539
Query: 974 RSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKE 1033
R E E+ K + RR+E R ++ +R+ KE+ +++E
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE-------QEEKIREQKEKIREQEE 592
Query: 1034 KEGEKAEKVTEKVVVKPEKTEK 1055
K E+ EK+ E+ + E+ EK
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEK 614
Score = 38.1 bits (87), Expect = 0.12
Identities = 67/324 (20%), Positives = 127/324 (39%), Gaps = 21/324 (6%)
Query: 827 EEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHH 886
E+ E +R + + E+ +E E K IRE E ++ R E+ R
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK---IRELEEKMHEQEKIREQEEKRQEE 402
Query: 887 TDANNQSACFEAPD----QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEP 942
Q E Q+ QEE+I E + R+ H ++ ++++ +
Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462
Query: 943 SAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGP---KPEKVYKSKSETRWGPRPSS 999
+ R +E I R +EK ++ IR E + EK++ + + R
Sbjct: 463 EMWRQEEKIR---EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW 519
Query: 1000 NRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLP 1059
+ E++ ++ + +K +R+ +E ++++EK GE+ EK+ E+ K + E+K
Sbjct: 520 RQEEKIREQEEKIREQEEK--IREQEEMMQEQEEKMGEQEEKMQEQ--EKMRRQEEKIRE 575
Query: 1060 PPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQ--KPSQDTEKPLEPVSTVQVEP 1117
+ I+ Q I + EK E Q K + EK E +Q +
Sbjct: 576 QEEKIREQKEKIREQE--EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633
Query: 1118 AVKTVNQQTMAAPVVKEEKQPEKV 1141
++ M V+ +Q EK+
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKM 657
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 104 bits (259), Expect = 1e-21
Identities = 90/389 (23%), Positives = 190/389 (48%), Gaps = 56/389 (14%)
Query: 339 EQGSNSPKENNSEDQGSKASENN---ENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPS 395
E+ +E + DQ K E E +K+ E T + Q + +
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 396 FNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEI 455
+ Q+R LP + L +Q +++ + ++++ D++E+W Q ++
Sbjct: 488 WQQQR-----LPEQKEKLWEQEKMQEQEEKI-----WEQEEKIRDQEEMWGQEKKMW--- 534
Query: 456 SAAVERARKRREEEERRMEEQRKAACAEKL-----KRLDEKLGILEKQPSPEEIRERERE 510
R K RE+E++ E++ K E+ +R+++K EK+ +E + RE E
Sbjct: 535 -----RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE 589
Query: 511 KEREREKELEKEQE---------QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561
+ REREK++ +E+E QE+E++ ++ E+ E+E+++++++EK E E++ +
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE 649
Query: 562 EKEKELERQK-----------EKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPM 610
++EK E+Q+ EK +E +KM+EQE++ +++ EK ++ E + + E M
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKM 709
Query: 611 VEKQ---ESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQF 667
E++ E E +EEE + +++ + ++E + E E E Q
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEK---MQEQEEEMWEQEEKMWEQEEKMWE 766
Query: 668 QKSLPPRFQR--QQEQMKQQQ--WQQQQQ 692
Q+ LP + ++ + E+M++Q+ W+Q+++
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQEEK 795
Score = 102 bits (254), Expect = 5e-21
Identities = 65/257 (25%), Positives = 141/257 (54%), Gaps = 6/257 (2%)
Query: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI-LEKQP 499
E+++W+Q R + E+ +K R++EER E+ + E+ R EK+ +EK
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMR 427
Query: 500 SPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKER 559
++++E+E++ + EK E+E+ +EREK+ ++ E +E+E++++K++E E+E
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM--WEQEE 485
Query: 560 KQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENS 619
K+ +++ L QKEK E +KM+EQE++ ++E+ + +E++ +E + + +E E+
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 545
Query: 620 CNKEEEPVFTRQDSNRSEKE-ATPVVHETEPESGSQPRPAVLSGYFKQFQKSL--PPRFQ 676
++EE + ++ ++E E E ++ Q ++ +K +
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 677 RQQEQMKQQQWQQQQQQ 693
R+QE+ Q+Q ++ Q+Q
Sbjct: 606 REQEEKMQEQEEKMQEQ 622
Score = 100 bits (250), Expect = 2e-20
Identities = 73/284 (25%), Positives = 149/284 (52%), Gaps = 29/284 (10%)
Query: 433 PSKQQVADEDEIWKQR---RRQQSEISAAVE---RARKRREEEERRMEEQRKAACAEKLK 486
P Q ++E+W+Q R Q+ +I E R +R E+E +M EQ EK+
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE-----EKMW 317
Query: 487 RLDEKLGILEKQPSPEEIREREREKEREREKELEKEQE---QEREKEREKDR------ER 537
R +++L EK+ +E RE+++ RE+E+++++++E ++ EK RE++ ER
Sbjct: 318 RQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377
Query: 538 QQEKEKELEKEQEKQREMEK------ERKQEKEKELERQKEKEKELQKMKEQEKECELEK 591
E+EK++ ++++K R+ E+ ER +EKE+ + Q++ ++++KM+E++K E EK
Sbjct: 378 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437
Query: 592 EREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPES 651
+ EEK++ E + +K E +E+E +Q+ N E+E + PE
Sbjct: 438 KTRDQEEKMQ-EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 652 GSQ--PRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
+ + + K +++ R Q + +++ W+Q++ +
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Score = 94.0 bits (232), Expect = 2e-18
Identities = 75/286 (26%), Positives = 150/286 (52%), Gaps = 36/286 (12%)
Query: 441 EDEIW---KQRRRQQSEISAAVERA----RKRREEEERRMEEQRKAACAEKLKRLDEKLG 493
E+ +W KQ R Q+ ++ ER + RE+EER E+++ EK++ ++K+
Sbjct: 375 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE-EKKMQ 433
Query: 494 ILEK------QPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEK 547
EK + EE R REREK+ E+E +EQE++ +K+ E E+++++ ++
Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Query: 548 EQEKQREMEKERKQEKEKELERQKEK----------EKEL---QKMKEQEKEC-ELEKER 593
++K++ E+E+ QE+E+++ Q+EK EK++ +KM+EQE + E E++
Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Query: 594 EKLEEKIEPREPNLEPMVEKQE----SENSCNKEEEPVFTRQDSNRSEKEATPVVHE--T 647
E+K+ +E +E ++QE + +EEE + R+ R E+E E
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613
Query: 648 EPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ--WQQQQ 691
E E Q + + ++ Q+ ++++++ +Q++ W+QQ+
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659
Score = 93.6 bits (231), Expect = 2e-18
Identities = 121/627 (19%), Positives = 272/627 (43%), Gaps = 80/627 (12%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
K++ A+ E ++SEI V+ +++ E + + + + E++ R +E+L
Sbjct: 224 KKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 283
Query: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKE-KELEKEQEKQR 553
EK+ +E + R++ER RE+E K +EQE + R++ R R+QEKE +E EKE +Q+
Sbjct: 284 QEKKIRKQE-EKMWRQEERLREQE-GKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 554 EM-EKERKQEKEKEL---ERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEP 609
E+ E+E + ++++E + +K +E+E + +++E+ E EK+ + E+K+ +E +
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 401
Query: 610 MVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQK 669
E+ + +E+E ++ + + R EK+ + E E ++ Q ++ +K
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKK----MQEQEKKTRDQEEKMQEEERIREREK 457
Query: 670 SLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLA 729
+ + ++E M++Q+ + Q+Q+ + + + +P + L++ + Q
Sbjct: 458 ----KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-LWEQEKMQEQE-- 510
Query: 730 SMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHI 789
+ W + D M G+ K + R+++M + E
Sbjct: 511 ----EKIWEQEEKIRDQEEMWGQ--------------EKKMWRQEKMREQEDQMWEQEEK 552
Query: 790 ARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSV 849
R + + +W Q+ K T+E E + +E++ +
Sbjct: 553 MR---------DQEQKMW---------DQEERMEKKTQEQEKKTWD---QEEKMREEERM 591
Query: 850 EHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQE 909
+ + + + +RE E ++ ++ + + Q + +Q+ QE
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651
Query: 910 ERISAVESQPSRKRSV-SHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPK 968
E++ + P +K + H Q+ +++ E I +E +E+ ++ +
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK-----------IWEQEKMEKKTQEQE 700
Query: 969 KEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEER 1028
K+ + + K + E R R EE R ++ +++ +EE
Sbjct: 701 KKTWDQE----------KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 1029 EQRKEKEGEKAEKVTEKVVVKPEKTEK 1055
+++EK E+ EK+ E+ + PE+ EK
Sbjct: 751 WEQEEKMWEQEEKMWEQQRL-PEQKEK 776
Score = 86.3 bits (212), Expect = 4e-16
Identities = 74/363 (20%), Positives = 163/363 (44%), Gaps = 38/363 (10%)
Query: 303 KELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENN- 361
K++ + + + + D+ W + D +++ ++ + +E + DQ K E
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 362 --ENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSH----LPPPPKLLAQ 415
E +K+ E + Q K+ + + QE K+ Q
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 416 QHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEE 475
+ ++Q +P + ++++W+ + Q+ E E +E+ E++ +E
Sbjct: 651 EEKMWEQQRLPEQ------------KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Query: 476 QRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDR 535
Q K ++ R +E + EK+ EE RE+E++ + ++E +EQE+E ++ EK
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMW 758
Query: 536 ERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER-- 593
E++++ ++ ++K++ E E+ QE+EK E++++ + +KM+ QE++ ++E+
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR 818
Query: 594 ---EKL---EEKIEPREPNL-----------EPMVEKQESENSCNKEEEPVFTRQDSNRS 636
EK+ EEK+ +E + E M EK + + +E+E Q+
Sbjct: 819 GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMR 878
Query: 637 EKE 639
E+E
Sbjct: 879 EQE 881
Score = 76.3 bits (186), Expect = 4e-13
Identities = 48/197 (24%), Positives = 107/197 (54%), Gaps = 14/197 (7%)
Query: 436 QQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIL 495
Q+ E+E ++R ++ E + ++ +E+E +M+EQ + ++ K +++ +
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555
E+Q PE ++E+ E EK QEQE+ E+E E+ +++E+++ ++EK R
Sbjct: 766 EQQRLPE---------QKEKLWEHEKMQEQEKIWEQE---EKMRDQEEKMRGQEEKMRGQ 813
Query: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQE 615
E++ + ++EK ++++ + +KM QE+ ++ + EK+EEK++ +E + EK
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEE--KMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Query: 616 SENSCNKEEEPVFTRQD 632
+ +E+E Q+
Sbjct: 872 GQEEKMREQEEKMRGQE 888
Score = 67.0 bits (162), Expect = 2e-10
Identities = 48/173 (27%), Positives = 94/173 (54%), Gaps = 8/173 (4%)
Query: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
K+ +E+ + +Q + Q + E+ + E+EE+ E++ K ++L EKL
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Query: 495 LEKQPSPEEIREREREKEREREKELEKEQEQER---EKEREKDRERQQEKEKELEKEQEK 551
EK E+I E+E EK R++E+++ ++E+ R EK R ++ + ++EK +E++
Sbjct: 780 HEKMQEQEKIWEQE-EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM 838
Query: 552 QREMEK----ERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600
+ EK E K E++ + + +K +E+E + ++EK E E++ EEKI
Sbjct: 839 WGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 47.4 bits (111), Expect = 2e-04
Identities = 130/692 (18%), Positives = 247/692 (35%), Gaps = 121/692 (17%)
Query: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELE-KEQEKQRE 554
E Q + + R ++ +R E EL KE++ + ++ K+K E +E+ E
Sbjct: 180 ELQRALSAVSTRHKKADRYIE-ELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAE 238
Query: 555 MEKERKQEKEKELERQKEKEK----ELQKMKEQEKECELEKEREKLEEKIEPREPNLEPM 610
EK Q KEL+R+ E+ K ++Q QE+ E+E + E+KI +E +
Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298
Query: 611 VEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKS 670
E+ + +E+E RQ+ E+E + E E E
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKE--LREQEKE-------------------- 336
Query: 671 LPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLAS 730
+ Q+E +Q++ Q+Q++ + Q + + R Q Q Q
Sbjct: 337 ----LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392
Query: 731 MGFDPR-WLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHI 789
+ R W D R+ R++ E + +E +
Sbjct: 393 RDQEERMW-----EQDERL------------------------REKEERMREQEKMWEQV 423
Query: 790 ARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSV 849
+ + + E + + E + K EE E +R + Q+Q
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ------- 476
Query: 850 EHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQE 909
E N E +E E Q Q+ P + + + ++K QE
Sbjct: 477 EENMWE--------QEEKEWQQQRL---------PEQKEKLWEQEKMQEQEEKIWE--QE 517
Query: 910 ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKK 969
E+I E +++ + ++ D Q E + + D +E +E+ ++ +K
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQED-QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK 576
Query: 970 EGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEERE 1029
+ + ++ K + E R R R EE ++R+ +E+ +
Sbjct: 577 KTW---------DQEEKMREEERMREREKKMREEE--------------EMMREQEEKMQ 613
Query: 1030 QRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPS 1089
+++EK E+ EK+ E+ E+ EK Q + Q +P + EK
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP----EQKEKLWE 669
Query: 1090 TETATLAQKPSQDTEK--PLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLV 1147
E +K + EK E + E KT +Q+ M E+ EK + ++
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER--EKKMREEEE 727
Query: 1148 IERPRPDSRPAVKKESTLPPRTYWKEARERDW 1179
+ R + + +++ W E E+ W
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMW-EQEEKMW 758
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.124 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 138,375,030
Number of Sequences: 37866
Number of extensions: 8813878
Number of successful extensions: 235165
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2252
Number of HSP's successfully gapped in prelim test: 3057
Number of HSP's that attempted gapping in prelim test: 42231
Number of HSP's gapped (non-prelim): 75028
length of query: 2817
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2697
effective length of database: 13,703,598
effective search space: 36958603806
effective search space used: 36958603806
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.