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Search of human proteins with 21703706
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21703706 WAP four-disulfide core domain 10A precursor [Homo
sapiens]
(79 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21703706 WAP four-disulfide core domain 10A precursor [Homo s... 171 2e-43
gi|26006869 WAP four-disulfide core domain 10B isoform a precurs... 108 1e-24
gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo s... 62 1e-10
gi|25188181 WAP four-disulfide core domain 13 precursor [Homo sa... 45 1e-05
gi|22218355 WAP four-disulfide core domain 11 precursor [Homo sa... 44 4e-05
gi|22218351 protease inhibitor WAP9 [Homo sapiens] 43 5e-05
gi|32307109 WAP four-disulfide core domain 3 precursor [Homo sap... 37 0.003
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 36 0.008
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 32 0.084
gi|56699495 WAP four-disulfide core domain 2 precursor [Homo sap... 32 0.11
gi|21717822 WAP four-disulfide core domain 5 precursor [Homo sap... 31 0.24
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 30 0.32
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 30 0.42
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 30 0.42
gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens] 30 0.54
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 29 0.93
gi|28212222 WFIKKN2 protein [Homo sapiens] 28 1.2
gi|89357932 keratin 5b [Homo sapiens] 28 1.6
gi|4507065 secretory leukocyte peptidase inhibitor precursor [Ho... 28 2.1
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 28 2.1
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 27 2.7
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens] 27 2.7
gi|42558258 F-box protein 33 [Homo sapiens] 27 3.5
gi|22779936 WAP four-disulfide core domain 6 precursor [Homo sap... 27 4.6
gi|20069858 WAP four-disulfide core domain 12 precursor [Homo sa... 27 4.6
gi|169205072 PREDICTED: hypothetical protein [Homo sapiens] 26 6.0
gi|113424011 PREDICTED: hypothetical protein [Homo sapiens] 26 6.0
gi|89363020 nuclear transcription factor, X-box binding-like 1 [... 26 6.0
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 26 7.9
gi|46249414 latent transforming growth factor beta binding prote... 26 7.9
>gi|21703706 WAP four-disulfide core domain 10A precursor [Homo
sapiens]
Length = 79
Score = 171 bits (432), Expect = 2e-43
Identities = 79/79 (100%), Positives = 79/79 (100%)
Query: 1 MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60
MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC
Sbjct: 1 MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60
Query: 61 QANNICCSTYCGNVCMSIL 79
QANNICCSTYCGNVCMSIL
Sbjct: 61 QANNICCSTYCGNVCMSIL 79
>gi|26006869 WAP four-disulfide core domain 10B isoform a
precursor [Homo sapiens]
Length = 73
Score = 108 bits (269), Expect = 1e-24
Identities = 51/79 (64%), Positives = 60/79 (75%), Gaps = 6/79 (7%)
Query: 1 MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60
MAPQTLL VLVLCVLLLQAQGGYRDK RMQ+ IKVC+++P + LC H C + C
Sbjct: 1 MAPQTLLLVLVLCVLLLQAQGGYRDKMRMQR------IKVCEKRPSIDLCIHHCSYFQKC 54
Query: 61 QANNICCSTYCGNVCMSIL 79
+ N ICCS +CGN+CMSIL
Sbjct: 55 ETNKICCSAFCGNICMSIL 73
>gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo
sapiens]
Length = 89
Score = 62.0 bits (149), Expect = 1e-10
Identities = 23/42 (54%), Positives = 31/42 (73%)
Query: 38 IKVCQQQPKLYLCKHLCESHRDCQANNICCSTYCGNVCMSIL 79
IKVC+++P + LC H C + C+ N ICCS +CGN+CMSIL
Sbjct: 48 IKVCEKRPSIDLCIHHCSYFQKCETNKICCSAFCGNICMSIL 89
>gi|25188181 WAP four-disulfide core domain 13 precursor [Homo
sapiens]
Length = 93
Score = 45.1 bits (105), Expect = 1e-05
Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 1 MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60
M P L LV+ L LQ G K+R+ K L P C P+ C HLC DC
Sbjct: 1 MKPVLPLQFLVVFCLALQLVPG-SPKQRVLKYILEPP--PCISAPEN--CTHLCTMQEDC 55
Query: 61 QANNICCSTYCGNVCMS 77
+ CCS++CG VC S
Sbjct: 56 EKGFQCCSSFCGIVCSS 72
>gi|22218355 WAP four-disulfide core domain 11 precursor [Homo
sapiens]
Length = 87
Score = 43.5 bits (101), Expect = 4e-05
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 7 LPVLV--LCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDCQANN 64
+P+L+ C +LL G R K+ +K L E C +P + C + C C+ N
Sbjct: 9 IPMLMTFFCTVLLSVLGEMRKKRYDRKELLLEE---CWGKPNVKECTNKCSKAFRCKDKN 65
Query: 65 I-CCSTYCGNVC 75
CC TYCGN+C
Sbjct: 66 YTCCWTYCGNIC 77
>gi|22218351 protease inhibitor WAP9 [Homo sapiens]
Length = 89
Score = 43.1 bits (100), Expect = 5e-05
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1 MAPQTLLPVLVLC--VLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHR 58
M P LL V+ + V+LL G + +K + E + C QP C+ C
Sbjct: 1 MKPWILLLVMFISGVVMLLPVLGSFWNKDPF--LDMIRETEQCWVQPPYKYCEKRCTKIM 58
Query: 59 DC-QANNICCSTYCGNVCM 76
C + N+ CC TYCGN+C+
Sbjct: 59 TCVRPNHTCCWTYCGNICL 77
>gi|32307109 WAP four-disulfide core domain 3 precursor [Homo
sapiens]
Length = 231
Score = 37.0 bits (84), Expect = 0.003
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 50 CKHLCESHRDCQANNICCSTYCGNVCMSI 78
CK LC+ C A CC+T CG +C I
Sbjct: 40 CKELCQGDELCPAEQKCCTTGCGRICRDI 68
Score = 34.7 bits (78), Expect = 0.017
Identities = 11/27 (40%), Positives = 15/27 (55%)
Query: 50 CKHLCESHRDCQANNICCSTYCGNVCM 76
C+ LC+ C + CCST CG C+
Sbjct: 133 CEELCDGDASCPQGHKCCSTGCGRTCL 159
Score = 29.3 bits (64), Expect = 0.71
Identities = 11/28 (39%), Positives = 14/28 (50%)
Query: 49 LCKHLCESHRDCQANNICCSTYCGNVCM 76
LC C +CQA CC + CG C+
Sbjct: 177 LCIVGCVMDENCQAGEKCCKSGCGRFCV 204
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 35.8 bits (81), Expect = 0.008
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 10/80 (12%)
Query: 1 MAPQTLLPVLVLCVLLLQAQG-GYRDKKRMQKTQLSPEIKV-CQQQPKLYLCKHLCESHR 58
M LL +LVL VLL QG G D ++ P+I+ C+ Q + +C R
Sbjct: 1 MGSSGLLSLLVLFVLLANVQGPGLTDWLFPRRC---PKIREECEFQER-----DVCTKDR 52
Query: 59 DCQANNICCSTYCGNVCMSI 78
CQ N CC CG C+ +
Sbjct: 53 QCQDNKKCCVFSCGKKCLDL 72
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 32.3 bits (72), Expect = 0.084
Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 9/72 (12%)
Query: 6 LLPVLVLCVLLLQAQG-----GYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60
L P+L L +LL G G + QLSP + V Q C+ C +DC
Sbjct: 4 LRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQST----CERECSRDQDC 59
Query: 61 QANNICCSTYCG 72
A CC CG
Sbjct: 60 AAAEKCCINVCG 71
>gi|56699495 WAP four-disulfide core domain 2 precursor [Homo
sapiens]
Length = 124
Score = 32.0 bits (71), Expect = 0.11
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
Query: 1 MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60
+A LL +L+ L+ G +KT + PE++ Q C C S +C
Sbjct: 9 LAAALLLSLLLFGFTLVSGTGA-------EKTGVCPELQADQN------CTQECVSDSEC 55
Query: 61 QANNICCSTYCGNVC 75
N CCS C C
Sbjct: 56 ADNLKCCSAGCATFC 70
Score = 29.3 bits (64), Expect = 0.71
Identities = 11/30 (36%), Positives = 14/30 (46%)
Query: 45 PKLYLCKHLCESHRDCQANNICCSTYCGNV 74
P+L LC+ C+ C CC CG V
Sbjct: 88 PQLGLCRDQCQVDSQCPGQMKCCRNGCGKV 117
>gi|21717822 WAP four-disulfide core domain 5 precursor [Homo
sapiens]
Length = 123
Score = 30.8 bits (68), Expect = 0.24
Identities = 10/24 (41%), Positives = 11/24 (45%)
Query: 52 HLCESHRDCQANNICCSTYCGNVC 75
HLC DC CC + CG C
Sbjct: 94 HLCHKDSDCSGKKRCCHSACGRDC 117
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 30.4 bits (67), Expect = 0.32
Identities = 10/28 (35%), Positives = 14/28 (50%)
Query: 51 KHLCESHRDCQANNICCSTYCGNVCMSI 78
+ +C R CQ N CC CG C+ +
Sbjct: 29 RDVCTKDRQCQDNKKCCVFSCGKKCLDL 56
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 30.0 bits (66), Expect = 0.42
Identities = 11/26 (42%), Positives = 13/26 (50%)
Query: 50 CKHLCESHRDCQANNICCSTYCGNVC 75
C C S DC + CC + CG VC
Sbjct: 165 CPPSCHSDIDCPQTDKCCESRCGFVC 190
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 30.0 bits (66), Expect = 0.42
Identities = 11/26 (42%), Positives = 13/26 (50%)
Query: 50 CKHLCESHRDCQANNICCSTYCGNVC 75
C C S DC + CC + CG VC
Sbjct: 165 CPPSCHSDIDCPQTDKCCESRCGFVC 190
>gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens]
Length = 680
Score = 29.6 bits (65), Expect = 0.54
Identities = 10/26 (38%), Positives = 12/26 (46%)
Query: 50 CKHLCESHRDCQANNICCSTYCGNVC 75
C CE +C CCS CG+ C
Sbjct: 147 CVESCEVDNECSGVKKCCSNGCGHTC 172
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 28.9 bits (63), Expect = 0.93
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
Query: 49 LCKHLCESHRDCQANNIC-CST-YCGNVCMSIL 79
+CK+ C R+C A NIC C Y G+ C + L
Sbjct: 1297 ICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL 1329
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 28.5 bits (62), Expect = 1.2
Identities = 8/23 (34%), Positives = 13/23 (56%)
Query: 50 CKHLCESHRDCQANNICCSTYCG 72
C+ CE+ ++C+ CC CG
Sbjct: 62 CRRECETDQECETYEKCCPNVCG 84
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 28.1 bits (61), Expect = 1.6
Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 4 QTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDCQAN 63
Q L PV C+ L+ Q ++ + ++ L E+K C+ Q + Y K+ E+HR
Sbjct: 156 QGLEPVFEACLDQLRKQ---LEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLE 212
Query: 64 N 64
N
Sbjct: 213 N 213
>gi|4507065 secretory leukocyte peptidase inhibitor precursor
[Homo sapiens]
Length = 132
Score = 27.7 bits (60), Expect = 2.1
Identities = 22/76 (28%), Positives = 26/76 (34%), Gaps = 3/76 (3%)
Query: 1 MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60
M L P LVL L A + K + P K Q L K C+S C
Sbjct: 1 MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQC---LRYKKPECQSDWQC 57
Query: 61 QANNICCSTYCGNVCM 76
CC CG C+
Sbjct: 58 PGKKRCCPDTCGIKCL 73
Score = 26.2 bits (56), Expect = 6.0
Identities = 9/26 (34%), Positives = 13/26 (50%)
Query: 52 HLCESHRDCQANNICCSTYCGNVCMS 77
+ CE C+ + CC CG C+S
Sbjct: 103 NFCEMDGQCKRDLKCCMGMCGKSCVS 128
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 27.7 bits (60), Expect = 2.1
Identities = 13/40 (32%), Positives = 16/40 (40%), Gaps = 15/40 (37%)
Query: 49 LCKHLCESHRDCQANNIC---------------CSTYCGN 73
LC C+SH CQ +C CS YCG+
Sbjct: 141 LCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGS 180
>gi|119395738 insulin receptor isoform Short precursor [Homo
sapiens]
Length = 1370
Score = 27.3 bits (59), Expect = 2.7
Identities = 10/27 (37%), Positives = 15/27 (55%), Gaps = 1/27 (3%)
Query: 49 LCKHLCESHRDCQANNICCSTYCGNVC 75
+C +C+SH C A +CC + C C
Sbjct: 218 VCPTICKSH-GCTAEGLCCHSECLGNC 243
>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
Length = 1382
Score = 27.3 bits (59), Expect = 2.7
Identities = 10/27 (37%), Positives = 15/27 (55%), Gaps = 1/27 (3%)
Query: 49 LCKHLCESHRDCQANNICCSTYCGNVC 75
+C +C+SH C A +CC + C C
Sbjct: 218 VCPTICKSH-GCTAEGLCCHSECLGNC 243
>gi|42558258 F-box protein 33 [Homo sapiens]
Length = 555
Score = 26.9 bits (58), Expect = 3.5
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 8/45 (17%)
Query: 10 LVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKL---YLCK 51
LVLCVL+ R+ + +QK L +I V QQQ L YL K
Sbjct: 188 LVLCVLV-----SIRNNRNLQKFSLFGDISVLQQQGSLSNTYLSK 227
>gi|22779936 WAP four-disulfide core domain 6 precursor [Homo
sapiens]
Length = 86
Score = 26.6 bits (57), Expect = 4.6
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 6/71 (8%)
Query: 6 LLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDCQANNI 65
LLP+LV +LL Q + + K P+IKV + ++ C RDC N
Sbjct: 6 LLPILVPFILLGDIQEPGHAEGILGKP--CPKIKVECEVEEI----DQCTKPRDCPENMK 59
Query: 66 CCSTYCGNVCM 76
CC G C+
Sbjct: 60 CCPFSRGKKCL 70
>gi|20069858 WAP four-disulfide core domain 12 precursor [Homo
sapiens]
Length = 111
Score = 26.6 bits (57), Expect = 4.6
Identities = 8/23 (34%), Positives = 12/23 (52%)
Query: 54 CESHRDCQANNICCSTYCGNVCM 76
C + +DC CC +CG C+
Sbjct: 49 CHTDQDCLGERKCCYLHCGFKCV 71
>gi|169205072 PREDICTED: hypothetical protein [Homo sapiens]
Length = 159
Score = 26.2 bits (56), Expect = 6.0
Identities = 17/66 (25%), Positives = 29/66 (43%), Gaps = 16/66 (24%)
Query: 3 PQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDCQA 62
P +L +L+L +LLL + GY +K++ + C H +CQ+
Sbjct: 4 PGWMLLLLLLLLLLLGSMAGYGPQKKLNLSHKG--------------IGEPCGRHEECQS 49
Query: 63 NNICCS 68
N CC+
Sbjct: 50 N--CCT 53
>gi|113424011 PREDICTED: hypothetical protein [Homo sapiens]
Length = 159
Score = 26.2 bits (56), Expect = 6.0
Identities = 17/66 (25%), Positives = 29/66 (43%), Gaps = 16/66 (24%)
Query: 3 PQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDCQA 62
P +L +L+L +LLL + GY +K++ + C H +CQ+
Sbjct: 4 PGWMLLLLLLLLLLLGSMAGYGPQKKLNLSHKG--------------IGEPCGRHEECQS 49
Query: 63 NNICCS 68
N CC+
Sbjct: 50 N--CCT 53
>gi|89363020 nuclear transcription factor, X-box binding-like 1
[Homo sapiens]
Length = 911
Score = 26.2 bits (56), Expect = 6.0
Identities = 12/29 (41%), Positives = 14/29 (48%), Gaps = 3/29 (10%)
Query: 46 KLYLCKHLCESHRDCQANNI---CCSTYC 71
K YLC+ C RDCQ + CC C
Sbjct: 462 KPYLCETKCVKMRDCQKHQCRRKCCPGNC 490
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 25.8 bits (55), Expect = 7.9
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 15/81 (18%)
Query: 2 APQTLLPVLVLCVLLLQAQGG--------YRDKKRM-QKTQLSPE-IKVCQQQPKLYLCK 51
APQTL+ + +L +L+ QG +D +R K PE ++C LC
Sbjct: 6 APQTLVLLTLLVAAVLRCQGQDVQEAGSCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCD 65
Query: 52 H-LCESHRDCQANNI----CC 67
+CE +DC + I CC
Sbjct: 66 DIICEDVKDCLSPEIPFGECC 86
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 25.8 bits (55), Expect = 7.9
Identities = 11/33 (33%), Positives = 15/33 (45%)
Query: 41 CQQQPKLYLCKHLCESHRDCQANNICCSTYCGN 73
C Q +L K CE +CQ ++C C N
Sbjct: 1106 CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRN 1138
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.137 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,554,639
Number of Sequences: 37866
Number of extensions: 144344
Number of successful extensions: 499
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 459
Number of HSP's gapped (non-prelim): 50
length of query: 79
length of database: 18,247,518
effective HSP length: 51
effective length of query: 28
effective length of database: 16,316,352
effective search space: 456857856
effective search space used: 456857856
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.