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Search of human proteins with 217035164
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217035164 coiled-coil domain containing 27 [Homo sapiens]
(656 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217035164 coiled-coil domain containing 27 [Homo sapiens] 1288 0.0
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 74 3e-13
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 72 1e-12
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 71 3e-12
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 71 3e-12
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 71 3e-12
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 69 1e-11
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 69 1e-11
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 67 5e-11
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 65 2e-10
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 65 3e-10
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens] 64 6e-10
gi|109255226 centrosomal protein 63 isoform c [Homo sapiens] 64 6e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 8e-10
gi|148746195 trichohyalin [Homo sapiens] 63 8e-10
gi|31982906 cingulin-like 1 [Homo sapiens] 63 1e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 62 1e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 2e-09
gi|7705415 hook homolog 1 [Homo sapiens] 62 2e-09
gi|83716024 kinesin family member 21B [Homo sapiens] 62 2e-09
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 61 3e-09
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 61 3e-09
gi|32698688 citron [Homo sapiens] 61 4e-09
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 60 5e-09
gi|16262452 cingulin [Homo sapiens] 60 5e-09
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 60 5e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 6e-09
gi|34577114 cytomatrix protein p110 [Homo sapiens] 60 6e-09
gi|46852174 kinesin family member 3A [Homo sapiens] 60 8e-09
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 60 8e-09
>gi|217035164 coiled-coil domain containing 27 [Homo sapiens]
Length = 656
Score = 1288 bits (3334), Expect = 0.0
Identities = 656/656 (100%), Positives = 656/656 (100%)
Query: 1 MFEAIFPSTPQARLKRDPREKPGLSSFRSTFRQQSSLGLCIPRLMLPKEASPSQRHSSMS 60
MFEAIFPSTPQARLKRDPREKPGLSSFRSTFRQQSSLGLCIPRLMLPKEASPSQRHSSMS
Sbjct: 1 MFEAIFPSTPQARLKRDPREKPGLSSFRSTFRQQSSLGLCIPRLMLPKEASPSQRHSSMS 60
Query: 61 SSMARALVLLQSMASRDARCPEWKPHQKPRTLSKSVQTISRYYRKTSEPKDAASLTGFMS 120
SSMARALVLLQSMASRDARCPEWKPHQKPRTLSKSVQTISRYYRKTSEPKDAASLTGFMS
Sbjct: 61 SSMARALVLLQSMASRDARCPEWKPHQKPRTLSKSVQTISRYYRKTSEPKDAASLTGFMS 120
Query: 121 KMELRRVFPTHPDCPQFSTRATSMSHCGSPTEADLSGEIDNSSETWRGTQDLFLARRGSD 180
KMELRRVFPTHPDCPQFSTRATSMSHCGSPTEADLSGEIDNSSETWRGTQDLFLARRGSD
Sbjct: 121 KMELRRVFPTHPDCPQFSTRATSMSHCGSPTEADLSGEIDNSSETWRGTQDLFLARRGSD 180
Query: 181 TNVDGYLLPFSKSICEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHC 240
TNVDGYLLPFSKSICEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHC
Sbjct: 181 TNVDGYLLPFSKSICEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHC 240
Query: 241 LSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRL 300
LSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRL
Sbjct: 241 LSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRL 300
Query: 301 SLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVS 360
SLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVS
Sbjct: 301 SLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVS 360
Query: 361 QMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQ 420
QMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQ
Sbjct: 361 QMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQ 420
Query: 421 VILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQA 480
VILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQA
Sbjct: 421 VILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQA 480
Query: 481 MTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQV 540
MTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQV
Sbjct: 481 MTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQV 540
Query: 541 ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTK 600
ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTK
Sbjct: 541 ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTK 600
Query: 601 SLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKSKKGTSK 656
SLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKSKKGTSK
Sbjct: 601 SLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKSKKGTSK 656
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 74.3 bits (181), Expect = 3e-13
Identities = 52/254 (20%), Positives = 135/254 (53%), Gaps = 15/254 (5%)
Query: 379 DRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSL 438
D D D++++E+ + + + S+L + + + L L E I + E + ++
Sbjct: 289 DEDIDAKQKEI----QSLKSQISALQKGYSKVLCQTLSERNSEITSLKNEGENLKRDNAI 344
Query: 439 ATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKK----H 494
+G+++SLQ+ + ++ Q++++ E L+ + +++ QL+A+ + S L+E+ K H
Sbjct: 345 TSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQEDAH 404
Query: 495 QEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQ 554
+E+ EK+ +L + Q+ ++E+++ K + + T+ S + + +++ ++ ++LQ
Sbjct: 405 RELREAQEKELKLCKTQIQDMEKEMKKLRAELRKSCTEQSVISRTLR-EKSKVE--EKLQ 461
Query: 555 EDLQSKKEMIQQ---AEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDI 611
ED + K +Q+ E ++ LE + +LE R+++I+AT+ ++D +
Sbjct: 462 EDSRRKLLQLQEMGNRESVIKINLERAVGQLEHFRSQVIKATYG-RAKPFRDKPVTDQQL 520
Query: 612 LEALQRIISERSDY 625
+E + ++ + ++
Sbjct: 521 IEKITQVTEDNINF 534
Score = 43.5 bits (101), Expect = 6e-04
Identities = 78/365 (21%), Positives = 148/365 (40%), Gaps = 75/365 (20%)
Query: 324 AAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDED 383
AA G+E + GE E + G GG + + +E + +E E +R
Sbjct: 653 AAGASGREGEAERGEARARGEAQSQNQATDGREGGKALEEYITQERNRAKETLEEER--- 709
Query: 384 SEERELPEEEEIPRRRASSLAESFEEE---LLAQLEEYEQVILDFQFNLEATRTRYSLAT 440
+ + E E + ++ +LA+S +E + LEE + + + + L R + L +
Sbjct: 710 ---KRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERL--ARQKEVLES 764
Query: 441 GVIASLQQQVDFQETQLRKI-NTENE-TLQKELRERRQQLQAMTDKFSNLREDKKHQEMM 498
+ ++ + E++ RK+ + EN T QKE+ E + K + +E KK Q++
Sbjct: 765 SIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLE 824
Query: 499 GLIEKDNQ---LLRQQVSELERKLT-------------------------KRDCVISELD 530
+ K + L Q+ L KL+ K + ++EL+
Sbjct: 825 NRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELE 884
Query: 531 T---KVSQLQEQVELDQNHLQRWKQLQE--------DLQSKKEMIQQAEQHTRVALESSQ 579
T K+ ++E++ L Q ++ + QE ++ KE I+Q Q T V+LE
Sbjct: 885 TTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQ-TIVSLEEKL 943
Query: 580 SRLERLRNKI----------------------IQATFSISGTKSLANEISDNDILEALQR 617
++ + KI + A + S K +A E +D+L A +
Sbjct: 944 QKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDLLAAQKE 1003
Query: 618 IISER 622
I+S++
Sbjct: 1004 ILSQQ 1008
Score = 38.5 bits (88), Expect = 0.020
Identities = 92/514 (17%), Positives = 210/514 (40%), Gaps = 71/514 (13%)
Query: 192 KSICEFDYLRKRRKSQTLSPVTSSSVASQSCL-RKRMPWYLSVIHEKDH---CLSELEIQ 247
K++ E+ + R +TL +S L +++ S+ EK+ L E + +
Sbjct: 688 KALEEYITQERNRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTR 747
Query: 248 VQKKDEEILLLQEEREAL----KMQLKCLL---KGKGQETSMSPGRREQLSDASLKLGRL 300
VQ+ +E + +E E+ K + K L K K Q+ +++++S++++ +
Sbjct: 748 VQELEERLARQKEVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKR 807
Query: 301 SLLKAFSRHE---EELQHWWQMQEESAAPERGKEPDLGGGEEDE-GLEGEPDGVEDTGAW 356
+A + + ++L++ Q+E + KE L D + E + T +
Sbjct: 808 KAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESL 867
Query: 357 GGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIP--RRRASSLAESFEEELLA- 413
S ++E +E E + + EER + +++ + + S FEEE++
Sbjct: 868 KAESLALKLNETLAELETTKT--KMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEY 925
Query: 414 --QLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQ---------------------- 449
Q++++ Q I+ + L+ + G IA+L+
Sbjct: 926 KEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSA 985
Query: 450 --------VDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLI 501
+D ++I ++ E + K ++ + M+D L E +K + ++
Sbjct: 986 KDMAYEHLIDDLLAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVV 1045
Query: 502 -----EKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQED 556
K+ +L+++++++ + K+D + L+ + QE+ L N ++ ++ ++
Sbjct: 1046 LVQQQSKELSVLKEKMAQMSSLVEKKDRELKALEEALRASQEKHRLQLN-TEKEQKPRKK 1104
Query: 557 LQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQ 616
Q+ +Q HT A SSQ Q +FS G + + ++++ +
Sbjct: 1105 TQTCDTSVQIEPVHTE-AFSSSQE----------QQSFSDLGVRCKGSR--HEEVIQRQK 1151
Query: 617 RIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKS 650
+ +SE +L++ Q+E+FL K+
Sbjct: 1152 KALSELRARIKELEKARSPDHKDHQNESFLDLKN 1185
Score = 37.0 bits (84), Expect = 0.058
Identities = 78/386 (20%), Positives = 151/386 (39%), Gaps = 84/386 (21%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSL 302
E+ + Q DE+I Q+E ++LK Q+ L KG + L
Sbjct: 280 EISQKCQVLDEDIDAKQKEIQSLKSQISALQKGYSK----------------------VL 317
Query: 303 LKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQM 362
+ S E+ ++EG + D +G +
Sbjct: 318 CQTLSERNSEIT----------------------SLKNEGENLKRDNAITSG------MV 349
Query: 363 GSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVI 422
S+ ++ ++E+ + ++E S + ++++ S +EE L Q + + ++
Sbjct: 350 SSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEE-LKQEDAHREL- 407
Query: 423 LDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMT 482
EA L I +++++ +LRK TE + + LRE+ + +
Sbjct: 408 ------REAQEKELKLCKTQIQDMEKEMKKLRAELRKSCTEQSVISRTLREKSKVEE--- 458
Query: 483 DKFSNLREDKKHQEMMGLIEKDNQ------LLRQQVSELERKLTKRDCVISELDTKVSQL 536
L+ED + ++++ L E N+ L + V +LE R VI +
Sbjct: 459 ----KLQEDSR-RKLLQLQEMGNRESVIKINLERAVGQLEH---FRSQVIKATYGRAKPF 510
Query: 537 QEQVELDQNHLQRWKQLQED---LQSKKEMIQQAEQHTRVALESSQSRLERLRNKI--IQ 591
+++ DQ +++ Q+ ED Q KK +Q+ Q + E + +E+LR + Q
Sbjct: 511 RDKPVTDQQLIEKITQVTEDNINFQQKKWTLQKETQLSNSKQEETTENIEKLRTSLDSCQ 570
Query: 592 ATFSIS-GTKSLANEISDNDILEALQ 616
A IS + L E+ D+L+ LQ
Sbjct: 571 ACMKISCCSHDLKKEV---DLLQHLQ 593
Score = 35.4 bits (80), Expect = 0.17
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 25/139 (17%)
Query: 511 QVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQ-------LQEDLQSKKEM 563
++S+ E + +D +I+ L +V++L ++V Q K+ L ED+ +K++
Sbjct: 239 RLSDYEIESKYKDVIIANLQNEVAELSQKVSETTTSRQNEKEISQKCQVLDEDIDAKQKE 298
Query: 564 IQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTK--SLANE----ISDNDI----LE 613
IQ +L+S S L++ +K++ T S ++ SL NE DN I +
Sbjct: 299 IQ--------SLKSQISALQKGYSKVLCQTLSERNSEITSLKNEGENLKRDNAITSGMVS 350
Query: 614 ALQRIISERSDYYNQLKQK 632
+LQ+ I + + QLK++
Sbjct: 351 SLQKDILAKDEQVQQLKEE 369
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.4 bits (176), Expect = 1e-12
Identities = 73/352 (20%), Positives = 168/352 (47%), Gaps = 32/352 (9%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDA 293
+ E++ + E E QV++++ ++ +E+ ++ Q + + +GQ REQ
Sbjct: 96 VREQEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 152
Query: 294 SLKLGRLSLLKAFSRHEE-ELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVED 352
+ G++ + R +E +++ E R +E +G E G + E G ++
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
Query: 353 TGAWGGVSQMGSVHEEGSEEEEEEEGDRDED--SEERELPEEEEIPRRRASSLAESFEEE 410
QMG EE ++EE+ G+++E +E ++ ++EE R++ + E E
Sbjct: 213 EQMQKQEEQMGE-QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEE-- 269
Query: 411 LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKE 470
Q+ E E+ +L + +T TG ++Q+ QE Q+R+ + +++
Sbjct: 270 ---QMREQEEQMLK-----QKEQTEQEEQTG---EQEEQMREQEEQMREQEEQMREQEEQ 318
Query: 471 LRERRQQL----QAMTDKFSNLREDK----KHQEMMGLIEKDNQLLRQQVSELERKLTKR 522
+RE+ +Q+ + M ++ + E K K +E MG E+ Q +QV + E ++ K+
Sbjct: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
Query: 523 DCVISELDTKVSQLQEQVELDQNHL----QRWKQLQEDLQSKKEMIQQAEQH 570
+ + + + ++ + +EQ+ + + ++ ++ +E + +KE +++ E+H
Sbjct: 379 EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Score = 69.7 bits (169), Expect = 8e-12
Identities = 75/379 (19%), Positives = 166/379 (43%), Gaps = 34/379 (8%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCL----------LKGKGQETSMSPGRREQLSD 292
EL+ + + EE+ L++ E+ +++ +K L L +GQ REQ
Sbjct: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQ 67
Query: 293 ASLKLGRLSLLKAFSRHEE-----------ELQHWWQMQEESAAPERGKEPDLGGG-EED 340
+ G++ + R +E E + + QE + G+ + G E
Sbjct: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
Query: 341 EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERE----LPEEEEIP 396
EG E +G Q G V E+ + E+E R+++ + RE + E+E
Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
Query: 397 RRRASSLAESFEE--ELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQE 454
R + + E + E Q+ E E+ + + + + + ++QV QE
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 455 TQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSE 514
Q++K + ++++RE+ +Q++ ++ +E + +E G E+ + +Q+ E
Sbjct: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE 307
Query: 515 LERKLTKRDCVISELDTKVSQLQEQV-----ELDQNHLQRWKQLQEDLQSKKEMIQQAEQ 569
E ++ +++ + E + ++ + +EQ+ ++ + Q WKQ +E + ++E +Q+ E+
Sbjct: 308 QEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ-EEQMGEQEEQMQKQEE 366
Query: 570 HTRVALESSQSRLERLRNK 588
R E + + E++R +
Sbjct: 367 QVRKQEEQMRKQEEQMRKQ 385
Score = 29.6 bits (65), Expect = 9.2
Identities = 20/78 (25%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Query: 505 NQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQE-DLQSKKEM 563
N+ L+++ +EL+ +L + SE+ + +L+ ++E D+ L + Q++E + Q +++
Sbjct: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
Query: 564 IQQAEQHTRVALESSQSR 581
Q EQ +V + Q R
Sbjct: 66 GQVREQEGQVREQEGQVR 83
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 71.2 bits (173), Expect = 3e-12
Identities = 97/440 (22%), Positives = 197/440 (44%), Gaps = 58/440 (13%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEEREAL---KMQLKCLLKG-KGQETSMSPGRREQ 289
+HE + LE Q+++ ++ L++E +A K++L+ ++ KGQ R EQ
Sbjct: 1534 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1593
Query: 290 LSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGE--EDEGLEGEP 347
+ R L + +E EL+ + + +AA ++ E DL E D ++G
Sbjct: 1594 NEEK-----RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Query: 348 DGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESF 407
+ ++ + ++ + ++ E E+ RDE + E++ A+S
Sbjct: 1649 EAIKQ------LRKLQAQMKDFQRELEDARASRDEIFATAKENEKK----------AKSL 1692
Query: 408 EEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETL 467
E +L+ QL+E + + +A + LA + +SL + Q+ + R++ L
Sbjct: 1693 EADLM-QLQE--DLAAAERARKQADLEKEELAEELASSLSGRNALQDEK-RRLEARIAQL 1748
Query: 468 QKELRERRQQLQAMTDKFSNLRED---------------KKHQEMMGLIEKDNQLLRQQV 512
++EL E + ++AM+D+ + +K++ +E+ N+ LR ++
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808
Query: 513 SELERKL-TKRDCVISELDTKVSQLQEQVELDQNHLQ-RWKQLQEDLQSKKEMIQQAEQH 570
E+E + +K I+ L+ K++QL+EQVE + Q K L++ + KE++ Q E
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Query: 571 TRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSD------ 624
++A E + + E+ ++ Q + + + I+ N LQR + E ++
Sbjct: 1869 RKMA-EQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN--RRKLQRELDEATESNEAMG 1925
Query: 625 -YYNQLKQKGVKVPPLQQSE 643
N LK K PP + S+
Sbjct: 1926 REVNALKSKLRGPPPQETSQ 1945
Score = 51.2 bits (121), Expect = 3e-06
Identities = 80/446 (17%), Positives = 183/446 (41%), Gaps = 58/446 (13%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E + L E+E +++++++ LQ ER+ + Q+ L E + E+ + L
Sbjct: 926 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL------EEQLE---EEEAARQKL 976
Query: 296 KLGRLSLLKAFSRHEEEL-----QHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGV 350
+L +++ + E+E+ Q+ +E ER + EE+E +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 351 EDTGAWGGVSQMGSVHEEGSEEEEEE-----EGDRDEDSEE------------RELPEEE 393
+ ++ EE S +E E+ EGD + E+ +L ++E
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 394 EIPRRRASSLAESFEEE--LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVD 451
E + + L + ++ L ++ E E I D Q +L++ R + A L ++++
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 452 FQETQL------------------RKINTENETLQKELRERRQQLQAMTDKFSNLRED-- 491
+T+L +++ + L +E R Q+Q M K + E+
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216
Query: 492 ---KKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQ 548
++ + ++K+ Q L ++ ++L +L E++ K +L+ QV+ Q+
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276
Query: 549 RWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISD 608
++ + +L K +Q + L ++ + +L + + + T+ L E +
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 609 N--DILEALQRIISERSDYYNQLKQK 632
++ L+++ ER+ +QL ++
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEE 1362
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/396 (20%), Positives = 164/396 (41%), Gaps = 61/396 (15%)
Query: 202 KRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEE 261
KR++ T V + A+ LR W L + ++ E ++Q K++E+ +E
Sbjct: 815 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 874
Query: 262 REALKMQLKCLLKGKGQETSMSPGRREQL---SDASLKLGRLSLLKAFSRHE-EELQHWW 317
++ + +LK L + Q T +EQL ++ + + + A + E EE+ H
Sbjct: 875 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 934
Query: 318 QMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEE 377
+ + E EED G + + + +M + E+ EEEE
Sbjct: 935 EARLEE--------------EEDRGQQLQAER----------KKMAQQMLDLEEQLEEEE 970
Query: 378 GDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYS 437
R + E+ E + + + +L + + E+ I D NL +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 438 LATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEM 497
T + + + E +L+K E ++EL + +++L+ F H+++
Sbjct: 1031 NLTKLKNKHESMISELEVRLKK----EEKSRQELEKLKRKLEGDASDF--------HEQI 1078
Query: 498 MGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQ----- 552
L+ Q++EL+ +L K++ EL +++L +++ N L++ ++
Sbjct: 1079 AD--------LQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 553 --LQEDLQSKKEMIQQAEQHTR---VALESSQSRLE 583
LQEDL S++ +AE+ R LE+ ++ LE
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Score = 42.0 bits (97), Expect = 0.002
Identities = 90/418 (21%), Positives = 163/418 (38%), Gaps = 54/418 (12%)
Query: 213 TSSSVASQSCLRKRMPWYLSVIHEK-DHCLSELEIQVQKKDEEILLLQEEREALKMQLKC 271
T S A+Q LR + ++V+ + D E QVQ+ ++ EE L QL+
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEE---LTEQLEQ 1221
Query: 272 LLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHE--------EELQHWWQMQEES 323
+ K ++ +D + +L L K H+ +ELQ E +
Sbjct: 1222 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 324 AAPERGKEPDLGGGEED-EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDE 382
A K L E G+ E +G A S + + +EE +
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1341
Query: 383 DSEERELPEEEEIPRRRASSLAESFEEELLA-------------QLEEYEQVILDFQFNL 429
++ R+L EE +SL + +EE+ A QL + ++ + DF +
Sbjct: 1342 STKLRQLEEER-------NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 430 EATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLR 489
EA I +L QQ + + K+ LQ+EL + L SNL
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL- 1453
Query: 490 EDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE---LDQNH 546
+KK ++ L+ ++ + + E +R + E +TK L +E +
Sbjct: 1454 -EKKQRKFDQLLAEEKNISSKYADERDR----AEAEAREKETKALSLARALEEALEAKEE 1508
Query: 547 LQRWKQL----QEDLQSKKE-------MIQQAEQHTRVALESSQSRLERLRNKIIQAT 593
L+R ++ EDL S K+ ++++++ +E +++LE L ++ +QAT
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE-LQAT 1565
Score = 38.5 bits (88), Expect = 0.020
Identities = 42/181 (23%), Positives = 80/181 (44%), Gaps = 9/181 (4%)
Query: 407 FEEELLAQLEEYEQV-ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENE 465
F +LA LEE + I D +A Y LA A QQQ+ T ++ I
Sbjct: 777 FRTGVLAHLEEERDLKITDVIMAFQAMCRGY-LARKAFAKRQQQL----TAMKVIQ---R 828
Query: 466 TLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCV 525
L+ R Q + K L + + +E M E + Q +++ + E +L + +
Sbjct: 829 NCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQK 888
Query: 526 ISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERL 585
S+L + + LQEQ++ + ++++ L +KK+ +++ LE + R ++L
Sbjct: 889 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 948
Query: 586 R 586
+
Sbjct: 949 Q 949
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 71.2 bits (173), Expect = 3e-12
Identities = 97/440 (22%), Positives = 197/440 (44%), Gaps = 58/440 (13%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEEREAL---KMQLKCLLKG-KGQETSMSPGRREQ 289
+HE + LE Q+++ ++ L++E +A K++L+ ++ KGQ R EQ
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
Query: 290 LSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGE--EDEGLEGEP 347
+ R L + +E EL+ + + +AA ++ E DL E D ++G
Sbjct: 1587 NEEK-----RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 348 DGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESF 407
+ ++ + ++ + ++ E E+ RDE + E++ A+S
Sbjct: 1642 EAIKQ------LRKLQAQMKDFQRELEDARASRDEIFATAKENEKK----------AKSL 1685
Query: 408 EEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETL 467
E +L+ QL+E + + +A + LA + +SL + Q+ + R++ L
Sbjct: 1686 EADLM-QLQE--DLAAAERARKQADLEKEELAEELASSLSGRNALQDEK-RRLEARIAQL 1741
Query: 468 QKELRERRQQLQAMTDKFSNLRED---------------KKHQEMMGLIEKDNQLLRQQV 512
++EL E + ++AM+D+ + +K++ +E+ N+ LR ++
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801
Query: 513 SELERKL-TKRDCVISELDTKVSQLQEQVELDQNHLQ-RWKQLQEDLQSKKEMIQQAEQH 570
E+E + +K I+ L+ K++QL+EQVE + Q K L++ + KE++ Q E
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Query: 571 TRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSD------ 624
++A E + + E+ ++ Q + + + I+ N LQR + E ++
Sbjct: 1862 RKMA-EQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN--RRKLQRELDEATESNEAMG 1918
Query: 625 -YYNQLKQKGVKVPPLQQSE 643
N LK K PP + S+
Sbjct: 1919 REVNALKSKLRGPPPQETSQ 1938
Score = 51.2 bits (121), Expect = 3e-06
Identities = 80/446 (17%), Positives = 183/446 (41%), Gaps = 58/446 (13%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E + L E+E +++++++ LQ ER+ + Q+ L E + E+ + L
Sbjct: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL------EEQLE---EEEAARQKL 969
Query: 296 KLGRLSLLKAFSRHEEEL-----QHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGV 350
+L +++ + E+E+ Q+ +E ER + EE+E +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 351 EDTGAWGGVSQMGSVHEEGSEEEEEE-----EGDRDEDSEE------------RELPEEE 393
+ ++ EE S +E E+ EGD + E+ +L ++E
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 394 EIPRRRASSLAESFEEE--LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVD 451
E + + L + ++ L ++ E E I D Q +L++ R + A L ++++
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 452 FQETQL------------------RKINTENETLQKELRERRQQLQAMTDKFSNLRED-- 491
+T+L +++ + L +E R Q+Q M K + E+
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209
Query: 492 ---KKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQ 548
++ + ++K+ Q L ++ ++L +L E++ K +L+ QV+ Q+
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269
Query: 549 RWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISD 608
++ + +L K +Q + L ++ + +L + + + T+ L E +
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 609 N--DILEALQRIISERSDYYNQLKQK 632
++ L+++ ER+ +QL ++
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEE 1355
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/396 (20%), Positives = 164/396 (41%), Gaps = 61/396 (15%)
Query: 202 KRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEE 261
KR++ T V + A+ LR W L + ++ E ++Q K++E+ +E
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
Query: 262 REALKMQLKCLLKGKGQETSMSPGRREQL---SDASLKLGRLSLLKAFSRHE-EELQHWW 317
++ + +LK L + Q T +EQL ++ + + + A + E EE+ H
Sbjct: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 318 QMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEE 377
+ + E EED G + + + +M + E+ EEEE
Sbjct: 928 EARLEE--------------EEDRGQQLQAER----------KKMAQQMLDLEEQLEEEE 963
Query: 378 GDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYS 437
R + E+ E + + + +L + + E+ I D NL +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 438 LATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEM 497
T + + + E +L+K E ++EL + +++L+ F H+++
Sbjct: 1024 NLTKLKNKHESMISELEVRLKK----EEKSRQELEKLKRKLEGDASDF--------HEQI 1071
Query: 498 MGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQ----- 552
L+ Q++EL+ +L K++ EL +++L +++ N L++ ++
Sbjct: 1072 AD--------LQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 553 --LQEDLQSKKEMIQQAEQHTR---VALESSQSRLE 583
LQEDL S++ +AE+ R LE+ ++ LE
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Score = 42.0 bits (97), Expect = 0.002
Identities = 90/418 (21%), Positives = 163/418 (38%), Gaps = 54/418 (12%)
Query: 213 TSSSVASQSCLRKRMPWYLSVIHEK-DHCLSELEIQVQKKDEEILLLQEEREALKMQLKC 271
T S A+Q LR + ++V+ + D E QVQ+ ++ EE L QL+
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEE---LTEQLEQ 1214
Query: 272 LLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHE--------EELQHWWQMQEES 323
+ K ++ +D + +L L K H+ +ELQ E +
Sbjct: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 324 AAPERGKEPDLGGGEED-EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDE 382
A K L E G+ E +G A S + + +EE +
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1334
Query: 383 DSEERELPEEEEIPRRRASSLAESFEEELLA-------------QLEEYEQVILDFQFNL 429
++ R+L EE +SL + +EE+ A QL + ++ + DF +
Sbjct: 1335 STKLRQLEEER-------NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
Query: 430 EATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLR 489
EA I +L QQ + + K+ LQ+EL + L SNL
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL- 1446
Query: 490 EDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE---LDQNH 546
+KK ++ L+ ++ + + E +R + E +TK L +E +
Sbjct: 1447 -EKKQRKFDQLLAEEKNISSKYADERDR----AEAEAREKETKALSLARALEEALEAKEE 1501
Query: 547 LQRWKQL----QEDLQSKKE-------MIQQAEQHTRVALESSQSRLERLRNKIIQAT 593
L+R ++ EDL S K+ ++++++ +E +++LE L ++ +QAT
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE-LQAT 1558
Score = 38.5 bits (88), Expect = 0.020
Identities = 42/181 (23%), Positives = 80/181 (44%), Gaps = 9/181 (4%)
Query: 407 FEEELLAQLEEYEQV-ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENE 465
F +LA LEE + I D +A Y LA A QQQ+ T ++ I
Sbjct: 770 FRTGVLAHLEEERDLKITDVIMAFQAMCRGY-LARKAFAKRQQQL----TAMKVIQ---R 821
Query: 466 TLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCV 525
L+ R Q + K L + + +E M E + Q +++ + E +L + +
Sbjct: 822 NCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQK 881
Query: 526 ISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERL 585
S+L + + LQEQ++ + ++++ L +KK+ +++ LE + R ++L
Sbjct: 882 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941
Query: 586 R 586
+
Sbjct: 942 Q 942
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 71.2 bits (173), Expect = 3e-12
Identities = 69/228 (30%), Positives = 115/228 (50%), Gaps = 15/228 (6%)
Query: 374 EEEEGDRDEDSE-ERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQV-ILDFQFNLEA 431
+EE+ RDE+ EL E+ + RRAS LA EEL A LE+ E+ L Q LEA
Sbjct: 1700 KEEQAGRDEEQRLAAELHEQAQALERRASLLAAEL-EELRAALEQGERSRRLAEQELLEA 1758
Query: 432 TRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQL-QAMTDKFSNLRE 490
T R +L L Q E L +++ E E +E RE ++ +A+TD E
Sbjct: 1759 TE-RLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEE 1817
Query: 491 DKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCV--------ISELDTKVSQLQEQVEL 542
KK Q+ +E+ + L Q V EL+ +L + + + +L+ KV +L+ +++
Sbjct: 1818 LKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDA 1877
Query: 543 DQ-NHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKI 589
+Q H + K +++ + KE+ QAE+ R L Q +++L++K+
Sbjct: 1878 EQKKHAEALKGVRKHERRVKELAYQAEE-DRKNLARMQDLVDKLQSKV 1924
Score = 52.4 bits (124), Expect = 1e-06
Identities = 96/413 (23%), Positives = 163/413 (39%), Gaps = 65/413 (15%)
Query: 266 KMQLKCLLKGKGQETSMSPGR--REQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQEES 323
K QL+ LK K E S R EQL A ++ +K EEL+ +++ E
Sbjct: 1122 KQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQ----KKIKELQARAEELEE--ELEAER 1175
Query: 324 AAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDED 383
AA R ++ E E L + E GA G EG + E E G +
Sbjct: 1176 AARARVEKQRAEAARELEELSERLE--EAGGASAG-------QREGCRKREAELGRLRRE 1226
Query: 384 SEERELPEEEEIP---RRRASSLAESFEE---------ELLAQLEEYEQVILDFQFNLEA 431
EE L E + R++A AE E+ +L + E + D N+E
Sbjct: 1227 LEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVET 1286
Query: 432 -TRTRYSL-------------ATGVIASLQQQVDFQETQLRKINTENETLQKELRERR-- 475
TR + S A + LQ+Q+ TQ ++ TE+ L + L E+
Sbjct: 1287 LTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECL 1346
Query: 476 -QQL--------QAMTDKFSNLREDKKHQEMMG----LIEKDNQLLRQQVSELERKLTKR 522
QL Q++ + L E+ K + + + D LLR+Q E +
Sbjct: 1347 ISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAEL 1406
Query: 523 DCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVA---LESSQ 579
++S+ + +V+Q + + E D +QR ++L+E + +Q+AE+ A S +
Sbjct: 1407 QRLLSKANAEVAQWRSKYEADA--IQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464
Query: 580 SRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQK 632
RL+ + T + S A + L+R + ER +++++
Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQ--RHLERALEERRRQEEEMQRE 1515
Score = 52.0 bits (123), Expect = 2e-06
Identities = 71/346 (20%), Positives = 136/346 (39%), Gaps = 58/346 (16%)
Query: 247 QVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAF 306
++Q + E+ L EE+E L QL +GK R QL + S L+
Sbjct: 1328 RLQTESGELSRLLEEKECLISQLS---RGKALAAQSLEELRRQLEEESKAKSALAHAVQA 1384
Query: 307 SRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVH 366
RH+ +L +E A E + E V+Q S +
Sbjct: 1385 LRHDCDLLREQHEEEAEAQAELQRLLSKANAE--------------------VAQWRSKY 1424
Query: 367 EEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQ 426
E + + EE + + R EE + A++ S E+ L E E V L+ +
Sbjct: 1425 EADAIQRTEELEEAKKKLALRLQEAEEGV--EAANAKCSSLEKAKLRLQTESEDVTLELE 1482
Query: 427 FNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFS 486
AT A+L ++ E L + + E +Q+EL +++ + + +
Sbjct: 1483 -----------RATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELF 1531
Query: 487 NLREDKKHQ-EMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQN 545
LR + E + ++++N+ L++++S+L +QV L
Sbjct: 1532 RLRHGHEEALEALETLKRENKNLQEEISDLT---------------------DQVSLSGK 1570
Query: 546 HLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQ 591
+Q ++ ++ L+ +K IQ A + ALE +++ R++ ++ Q
Sbjct: 1571 SIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQ 1616
Score = 43.1 bits (100), Expect = 8e-04
Identities = 52/249 (20%), Positives = 105/249 (42%), Gaps = 41/249 (16%)
Query: 363 GSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVI 422
G V E E+EEE + D + R+L +E EL +++ + +
Sbjct: 966 GKVKELSERLEDEEEVNADLAARRRKLEDECT---------------ELKKDIDDLKLTL 1010
Query: 423 LDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMT 482
+ +AT + T +A+L + V + + + ++ +L+ ++ A+T
Sbjct: 1011 AKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALT 1070
Query: 483 -----------DKFSNLREDKK----HQEMMGLIEKDNQLLRQQVSE-------LERKLT 520
D +L ++KK + +E D +L ++ V++ LE KL
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130
Query: 521 KRDCVISELDTKVSQ---LQEQVELDQNHLQ-RWKQLQEDLQSKKEMIQQAEQHTRVALE 576
K+D +S+L +V L Q++ LQ R ++L+E+L++++ + E+ A
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAAR 1190
Query: 577 SSQSRLERL 585
+ ERL
Sbjct: 1191 ELEELSERL 1199
Score = 43.1 bits (100), Expect = 8e-04
Identities = 73/345 (21%), Positives = 126/345 (36%), Gaps = 69/345 (20%)
Query: 241 LSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRL 300
L++LE+Q+ + Q ++ QLK G+ +E ++ EQ A R
Sbjct: 1671 LNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQ---AQALERRA 1727
Query: 301 SLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEE--------DEGLEGEPDGVED 352
SLL A EL+ E+ R E +L E + GL + +E
Sbjct: 1728 SLLAA------ELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEA 1781
Query: 353 TGAW--GGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEE 410
A G V + E E+ ++ D +EE + ++ R E E
Sbjct: 1782 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1841
Query: 411 LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKE 470
L A+LEE EQ LR + + L+ +
Sbjct: 1842 LQARLEEAEQ----------------------------------AALRGGKKQVQKLEAK 1867
Query: 471 LRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQ---QVSELERKLTKRDCVIS 527
+RE +L A E KKH E + + K + +++ Q E + L + ++
Sbjct: 1868 VRELEAELDA---------EQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVD 1918
Query: 528 ELDTKVS----QLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAE 568
+L +KV Q +E + +L ++++ Q +L +E AE
Sbjct: 1919 KLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAE 1963
Score = 34.7 bits (78), Expect = 0.29
Identities = 70/361 (19%), Positives = 141/361 (39%), Gaps = 27/361 (7%)
Query: 235 HEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDAS 294
+E D E++ KK + L + E KC K + + + D +
Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQT-----ESEDVT 1478
Query: 295 LKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGE-EDEGLEGEPDGVEDT 353
L+L R + A + +++ +H + EE E + +L + E GL E +
Sbjct: 1479 LELERAT--SAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH- 1535
Query: 354 GAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLA 413
G + + ++ E +EE D+ S + +E E + E + E+ A
Sbjct: 1536 GHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELE----KTKKALEGEKSEIQA 1591
Query: 414 QLEEYEQVILDFQFNLEATRT-RYSLATGVIASLQQQVDFQETQLRKINTENETLQKELR 472
LEE E + LE T+T R L ++ ++ +VD +L + + E L++ +
Sbjct: 1592 ALEEAEGAL-----ELEETKTLRIQLE---LSQVKAEVD---RKLAEKDEECANLRRNHQ 1640
Query: 473 ERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTK 532
+ LQA D + R + + +E D L Q+ R+ T+ + +
Sbjct: 1641 RAVESLQASLDAETRARNEALRLKKK--MEGDLNDLELQLGHATRQATEAQAATRLMQAQ 1698
Query: 533 VSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQA 592
+ + Q + +Q + + L+ + ++ + R ALE + ++++A
Sbjct: 1699 LKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEA 1758
Query: 593 T 593
T
Sbjct: 1759 T 1759
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/388 (21%), Positives = 179/388 (46%), Gaps = 54/388 (13%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEEREAL---KMQLKCLLKG-KGQETSMSPGRREQ 289
+HE + LE Q+++ ++ L++E +A K++L+ ++ KGQ R EQ
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
Query: 290 LSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGE--EDEGLEGEP 347
+ R L + +E EL+ + + +AA ++ E DL E D ++G
Sbjct: 1587 NEEK-----RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 348 DGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESF 407
+ ++ + ++ + ++ E E+ RDE + E++ A+S
Sbjct: 1642 EAIKQ------LRKLQAQMKDFQRELEDARASRDEIFATAKENEKK----------AKSL 1685
Query: 408 EEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETL 467
E +L+ QL+E + + +A + LA + +SL + Q+ + R++ L
Sbjct: 1686 EADLM-QLQE--DLAAAERARKQADLEKEELAEELASSLSGRNALQDEK-RRLEARIAQL 1741
Query: 468 QKELRERRQQLQAMTDKFSNLRED---------------KKHQEMMGLIEKDNQLLRQQV 512
++EL E + ++AM+D+ + +K++ +E+ N+ LR ++
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801
Query: 513 SELERKL-TKRDCVISELDTKVSQLQEQVELDQNHLQ-RWKQLQEDLQSKKEMIQQAEQH 570
E+E + +K I+ L+ K++QL+EQVE + Q K L++ + KE++ Q E
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Query: 571 TRVA------LESSQSRLERLRNKIIQA 592
++A E +R+++L+ ++ +A
Sbjct: 1862 RKMAEQYKEQAEKGNARVKQLKRQLEEA 1889
Score = 51.2 bits (121), Expect = 3e-06
Identities = 80/446 (17%), Positives = 183/446 (41%), Gaps = 58/446 (13%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E + L E+E +++++++ LQ ER+ + Q+ L E + E+ + L
Sbjct: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL------EEQLE---EEEAARQKL 969
Query: 296 KLGRLSLLKAFSRHEEEL-----QHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGV 350
+L +++ + E+E+ Q+ +E ER + EE+E +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 351 EDTGAWGGVSQMGSVHEEGSEEEEEE-----EGDRDEDSEE------------RELPEEE 393
+ ++ EE S +E E+ EGD + E+ +L ++E
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 394 EIPRRRASSLAESFEEE--LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVD 451
E + + L + ++ L ++ E E I D Q +L++ R + A L ++++
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 452 FQETQL------------------RKINTENETLQKELRERRQQLQAMTDKFSNLRED-- 491
+T+L +++ + L +E R Q+Q M K + E+
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209
Query: 492 ---KKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQ 548
++ + ++K+ Q L ++ ++L +L E++ K +L+ QV+ Q+
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269
Query: 549 RWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISD 608
++ + +L K +Q + L ++ + +L + + + T+ L E +
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 609 N--DILEALQRIISERSDYYNQLKQK 632
++ L+++ ER+ +QL ++
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEE 1355
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/396 (20%), Positives = 164/396 (41%), Gaps = 61/396 (15%)
Query: 202 KRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEE 261
KR++ T V + A+ LR W L + ++ E ++Q K++E+ +E
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
Query: 262 REALKMQLKCLLKGKGQETSMSPGRREQL---SDASLKLGRLSLLKAFSRHE-EELQHWW 317
++ + +LK L + Q T +EQL ++ + + + A + E EE+ H
Sbjct: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 318 QMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEE 377
+ + E EED G + + + +M + E+ EEEE
Sbjct: 928 EARLEE--------------EEDRGQQLQAER----------KKMAQQMLDLEEQLEEEE 963
Query: 378 GDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYS 437
R + E+ E + + + +L + + E+ I D NL +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 438 LATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEM 497
T + + + E +L+K E ++EL + +++L+ F H+++
Sbjct: 1024 NLTKLKNKHESMISELEVRLKK----EEKSRQELEKLKRKLEGDASDF--------HEQI 1071
Query: 498 MGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQ----- 552
L+ Q++EL+ +L K++ EL +++L +++ N L++ ++
Sbjct: 1072 AD--------LQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 553 --LQEDLQSKKEMIQQAEQHTR---VALESSQSRLE 583
LQEDL S++ +AE+ R LE+ ++ LE
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Score = 47.0 bits (110), Expect = 6e-05
Identities = 88/432 (20%), Positives = 166/432 (38%), Gaps = 70/432 (16%)
Query: 232 SVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLS 291
S + + L E Q ++ L+EER +L+ QL ++ K QLS
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 292 DASLKLGRLS-----LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEED-EGLEG 345
D+ KL + L + R ++E+++ Q EE AA E +++ + L
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 346 EPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRR-RASSLA 404
+ D VS + + + EE+ + ++ER+ E E + +A SLA
Sbjct: 1435 DLDNQRQL-----VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1489
Query: 405 ESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTEN 464
+ EE L A+ EE E+ + +E + + + V E R + T+
Sbjct: 1490 RALEEALEAK-EELERTNKMLKAEMEDLVSSKD-------DVGKNVHELEKSKRALETQM 1541
Query: 465 ETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDC 524
E ++ +L E +LQA D + LR + Q + G E+D Q +Q E R
Sbjct: 1542 EEMKTQLEELEDELQATED--AKLRLEVNMQALKGQFERDLQARDEQNEEKRR------- 1592
Query: 525 VISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLER 584
QLQ L + ++ + +A + +
Sbjct: 1593 ---------------------------QLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 585 LRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEA 644
L++ +QA +I G + + ++ L+++ ++ D+ +L+ + E
Sbjct: 1626 LKDLELQADSAIKGRE---------EAIKQLRKLQAQMKDFQRELEDARA-----SRDEI 1671
Query: 645 FLTSKSKKGTSK 656
F T+K + +K
Sbjct: 1672 FATAKENEKKAK 1683
Score = 42.0 bits (97), Expect = 0.002
Identities = 90/418 (21%), Positives = 163/418 (38%), Gaps = 54/418 (12%)
Query: 213 TSSSVASQSCLRKRMPWYLSVIHEK-DHCLSELEIQVQKKDEEILLLQEEREALKMQLKC 271
T S A+Q LR + ++V+ + D E QVQ+ ++ EE L QL+
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEE---LTEQLEQ 1214
Query: 272 LLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHE--------EELQHWWQMQEES 323
+ K ++ +D + +L L K H+ +ELQ E +
Sbjct: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 324 AAPERGKEPDLGGGEED-EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDE 382
A K L E G+ E +G A S + + +EE +
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1334
Query: 383 DSEERELPEEEEIPRRRASSLAESFEEELLA-------------QLEEYEQVILDFQFNL 429
++ R+L EE +SL + +EE+ A QL + ++ + DF +
Sbjct: 1335 STKLRQLEEER-------NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
Query: 430 EATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLR 489
EA I +L QQ + + K+ LQ+EL + L SNL
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL- 1446
Query: 490 EDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE---LDQNH 546
+KK ++ L+ ++ + + E +R + E +TK L +E +
Sbjct: 1447 -EKKQRKFDQLLAEEKNISSKYADERDR----AEAEAREKETKALSLARALEEALEAKEE 1501
Query: 547 LQRWKQL----QEDLQSKKE-------MIQQAEQHTRVALESSQSRLERLRNKIIQAT 593
L+R ++ EDL S K+ ++++++ +E +++LE L ++ +QAT
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE-LQAT 1558
Score = 38.5 bits (88), Expect = 0.020
Identities = 42/181 (23%), Positives = 80/181 (44%), Gaps = 9/181 (4%)
Query: 407 FEEELLAQLEEYEQV-ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENE 465
F +LA LEE + I D +A Y LA A QQQ+ T ++ I
Sbjct: 770 FRTGVLAHLEEERDLKITDVIMAFQAMCRGY-LARKAFAKRQQQL----TAMKVIQ---R 821
Query: 466 TLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCV 525
L+ R Q + K L + + +E M E + Q +++ + E +L + +
Sbjct: 822 NCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQK 881
Query: 526 ISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERL 585
S+L + + LQEQ++ + ++++ L +KK+ +++ LE + R ++L
Sbjct: 882 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941
Query: 586 R 586
+
Sbjct: 942 Q 942
Score = 33.1 bits (74), Expect = 0.83
Identities = 28/132 (21%), Positives = 63/132 (47%), Gaps = 14/132 (10%)
Query: 365 VHE-EGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEE------ELLAQLEE 417
+HE EG+ + + + +++ +L E+ E R + +S ++ E+L Q+E+
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
Query: 418 YEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQ 477
++ ++ E R + L++Q++ E + ++IN LQ+EL E +
Sbjct: 1861 ERKMAEQYKEQAEKGNAR-------VKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
Query: 478 LQAMTDKFSNLR 489
+AM + + L+
Sbjct: 1914 NEAMGREVNALK 1925
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 69.3 bits (168), Expect = 1e-11
Identities = 85/388 (21%), Positives = 179/388 (46%), Gaps = 54/388 (13%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEEREAL---KMQLKCLLKG-KGQETSMSPGRREQ 289
+HE + LE Q+++ ++ L++E +A K++L+ ++ KGQ R EQ
Sbjct: 1534 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1593
Query: 290 LSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGE--EDEGLEGEP 347
+ R L + +E EL+ + + +AA ++ E DL E D ++G
Sbjct: 1594 NEEK-----RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Query: 348 DGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESF 407
+ ++ + ++ + ++ E E+ RDE + E++ A+S
Sbjct: 1649 EAIKQ------LRKLQAQMKDFQRELEDARASRDEIFATAKENEKK----------AKSL 1692
Query: 408 EEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETL 467
E +L+ QL+E + + +A + LA + +SL + Q+ + R++ L
Sbjct: 1693 EADLM-QLQE--DLAAAERARKQADLEKEELAEELASSLSGRNALQDEK-RRLEARIAQL 1748
Query: 468 QKELRERRQQLQAMTDKFSNLRED---------------KKHQEMMGLIEKDNQLLRQQV 512
++EL E + ++AM+D+ + +K++ +E+ N+ LR ++
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808
Query: 513 SELERKL-TKRDCVISELDTKVSQLQEQVELDQNHLQ-RWKQLQEDLQSKKEMIQQAEQH 570
E+E + +K I+ L+ K++QL+EQVE + Q K L++ + KE++ Q E
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Query: 571 TRVA------LESSQSRLERLRNKIIQA 592
++A E +R+++L+ ++ +A
Sbjct: 1869 RKMAEQYKEQAEKGNARVKQLKRQLEEA 1896
Score = 51.2 bits (121), Expect = 3e-06
Identities = 80/446 (17%), Positives = 183/446 (41%), Gaps = 58/446 (13%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E + L E+E +++++++ LQ ER+ + Q+ L E + E+ + L
Sbjct: 926 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL------EEQLE---EEEAARQKL 976
Query: 296 KLGRLSLLKAFSRHEEEL-----QHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGV 350
+L +++ + E+E+ Q+ +E ER + EE+E +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 351 EDTGAWGGVSQMGSVHEEGSEEEEEE-----EGDRDEDSEE------------RELPEEE 393
+ ++ EE S +E E+ EGD + E+ +L ++E
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 394 EIPRRRASSLAESFEEE--LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVD 451
E + + L + ++ L ++ E E I D Q +L++ R + A L ++++
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 452 FQETQL------------------RKINTENETLQKELRERRQQLQAMTDKFSNLRED-- 491
+T+L +++ + L +E R Q+Q M K + E+
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216
Query: 492 ---KKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQ 548
++ + ++K+ Q L ++ ++L +L E++ K +L+ QV+ Q+
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276
Query: 549 RWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISD 608
++ + +L K +Q + L ++ + +L + + + T+ L E +
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 609 N--DILEALQRIISERSDYYNQLKQK 632
++ L+++ ER+ +QL ++
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEE 1362
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/396 (20%), Positives = 164/396 (41%), Gaps = 61/396 (15%)
Query: 202 KRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEE 261
KR++ T V + A+ LR W L + ++ E ++Q K++E+ +E
Sbjct: 815 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 874
Query: 262 REALKMQLKCLLKGKGQETSMSPGRREQL---SDASLKLGRLSLLKAFSRHE-EELQHWW 317
++ + +LK L + Q T +EQL ++ + + + A + E EE+ H
Sbjct: 875 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 934
Query: 318 QMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEE 377
+ + E EED G + + + +M + E+ EEEE
Sbjct: 935 EARLEE--------------EEDRGQQLQAER----------KKMAQQMLDLEEQLEEEE 970
Query: 378 GDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYS 437
R + E+ E + + + +L + + E+ I D NL +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 438 LATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEM 497
T + + + E +L+K E ++EL + +++L+ F H+++
Sbjct: 1031 NLTKLKNKHESMISELEVRLKK----EEKSRQELEKLKRKLEGDASDF--------HEQI 1078
Query: 498 MGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQ----- 552
L+ Q++EL+ +L K++ EL +++L +++ N L++ ++
Sbjct: 1079 AD--------LQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 553 --LQEDLQSKKEMIQQAEQHTR---VALESSQSRLE 583
LQEDL S++ +AE+ R LE+ ++ LE
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Score = 47.0 bits (110), Expect = 6e-05
Identities = 88/432 (20%), Positives = 166/432 (38%), Gaps = 70/432 (16%)
Query: 232 SVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLS 291
S + + L E Q ++ L+EER +L+ QL ++ K QLS
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 292 DASLKLGRLS-----LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEED-EGLEG 345
D+ KL + L + R ++E+++ Q EE AA E +++ + L
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 346 EPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRR-RASSLA 404
+ D VS + + + EE+ + ++ER+ E E + +A SLA
Sbjct: 1442 DLDNQRQL-----VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1496
Query: 405 ESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTEN 464
+ EE L A+ EE E+ + +E + + + V E R + T+
Sbjct: 1497 RALEEALEAK-EELERTNKMLKAEMEDLVSSKD-------DVGKNVHELEKSKRALETQM 1548
Query: 465 ETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDC 524
E ++ +L E +LQA D + LR + Q + G E+D Q +Q E R
Sbjct: 1549 EEMKTQLEELEDELQATED--AKLRLEVNMQALKGQFERDLQARDEQNEEKRR------- 1599
Query: 525 VISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLER 584
QLQ L + ++ + +A + +
Sbjct: 1600 ---------------------------QLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1632
Query: 585 LRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEA 644
L++ +QA +I G + + ++ L+++ ++ D+ +L+ + E
Sbjct: 1633 LKDLELQADSAIKGRE---------EAIKQLRKLQAQMKDFQRELEDARA-----SRDEI 1678
Query: 645 FLTSKSKKGTSK 656
F T+K + +K
Sbjct: 1679 FATAKENEKKAK 1690
Score = 42.0 bits (97), Expect = 0.002
Identities = 90/418 (21%), Positives = 163/418 (38%), Gaps = 54/418 (12%)
Query: 213 TSSSVASQSCLRKRMPWYLSVIHEK-DHCLSELEIQVQKKDEEILLLQEEREALKMQLKC 271
T S A+Q LR + ++V+ + D E QVQ+ ++ EE L QL+
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEE---LTEQLEQ 1221
Query: 272 LLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHE--------EELQHWWQMQEES 323
+ K ++ +D + +L L K H+ +ELQ E +
Sbjct: 1222 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 324 AAPERGKEPDLGGGEED-EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDE 382
A K L E G+ E +G A S + + +EE +
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1341
Query: 383 DSEERELPEEEEIPRRRASSLAESFEEELLA-------------QLEEYEQVILDFQFNL 429
++ R+L EE +SL + +EE+ A QL + ++ + DF +
Sbjct: 1342 STKLRQLEEER-------NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 430 EATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLR 489
EA I +L QQ + + K+ LQ+EL + L SNL
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL- 1453
Query: 490 EDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE---LDQNH 546
+KK ++ L+ ++ + + E +R + E +TK L +E +
Sbjct: 1454 -EKKQRKFDQLLAEEKNISSKYADERDR----AEAEAREKETKALSLARALEEALEAKEE 1508
Query: 547 LQRWKQL----QEDLQSKKE-------MIQQAEQHTRVALESSQSRLERLRNKIIQAT 593
L+R ++ EDL S K+ ++++++ +E +++LE L ++ +QAT
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE-LQAT 1565
Score = 38.5 bits (88), Expect = 0.020
Identities = 42/181 (23%), Positives = 80/181 (44%), Gaps = 9/181 (4%)
Query: 407 FEEELLAQLEEYEQV-ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENE 465
F +LA LEE + I D +A Y LA A QQQ+ T ++ I
Sbjct: 777 FRTGVLAHLEEERDLKITDVIMAFQAMCRGY-LARKAFAKRQQQL----TAMKVIQ---R 828
Query: 466 TLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCV 525
L+ R Q + K L + + +E M E + Q +++ + E +L + +
Sbjct: 829 NCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQK 888
Query: 526 ISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERL 585
S+L + + LQEQ++ + ++++ L +KK+ +++ LE + R ++L
Sbjct: 889 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 948
Query: 586 R 586
+
Sbjct: 949 Q 949
Score = 33.1 bits (74), Expect = 0.83
Identities = 28/132 (21%), Positives = 63/132 (47%), Gaps = 14/132 (10%)
Query: 365 VHE-EGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEE------ELLAQLEE 417
+HE EG+ + + + +++ +L E+ E R + +S ++ E+L Q+E+
Sbjct: 1808 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1867
Query: 418 YEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQ 477
++ ++ E R + L++Q++ E + ++IN LQ+EL E +
Sbjct: 1868 ERKMAEQYKEQAEKGNAR-------VKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920
Query: 478 LQAMTDKFSNLR 489
+AM + + L+
Sbjct: 1921 NEAMGREVNALK 1932
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 67.0 bits (162), Expect = 5e-11
Identities = 100/433 (23%), Positives = 185/433 (42%), Gaps = 60/433 (13%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEEREAL---KMQLKCLLKGKGQETSMSPGRREQL 290
+HE + LE QV++ ++ L++E +A K++L+ ++ + R++
Sbjct: 1527 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586
Query: 291 SDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEED-EGLEGEPDG 349
++ +L L+K E EL+ + + + A ++ E DL E E D
Sbjct: 1587 NEEKKRL----LIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDE 1642
Query: 350 VEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDE---DSEERELP-----------EEEEI 395
V + ++ + ++ E EE RDE S+E E +EE
Sbjct: 1643 VIKQ-----LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELA 1697
Query: 396 PRRRASSLAESFEEELLAQLEEY---EQVILDFQFNLEATRTRYSLATGVIASLQQQVDF 452
RA AE +EL ++ + +LD + LEA R + + Q ++
Sbjct: 1698 SSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA---RIAQLEEELEEEQSNMEL 1754
Query: 453 QETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQV 512
+ RK + +TL EL R Q K N R+ +E+ N+ L+ ++
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQ----KSDNARQQ---------LERQNKELKAKL 1801
Query: 513 SELERKL-TKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSK-KEMIQQAEQH 570
ELE + +K IS L+ K+ QL+EQ+E + +L + K KE+ Q E
Sbjct: 1802 QELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDE 1861
Query: 571 TRVA------LESSQSRLERLRNKI----IQATFSISGTKSLANEISDNDILEALQRIIS 620
R A +E + +R+++L+ ++ +AT + + + L E+ +D EA + +
Sbjct: 1862 RRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL--DDATEANEGLSR 1919
Query: 621 ERSDYYNQLKQKG 633
E S N+L++ G
Sbjct: 1920 EVSTLKNRLRRGG 1932
Score = 57.4 bits (137), Expect = 4e-08
Identities = 105/450 (23%), Positives = 189/450 (42%), Gaps = 72/450 (16%)
Query: 187 LLPFSKSICEFDYLRKR--RKSQTLSP--VTSSSVASQSCLRKRMPWYLSVIHEKDHCLS 242
++ F +++C RK +K Q LS V + A+ LR W + + ++
Sbjct: 789 IIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVT 848
Query: 243 ELEIQVQKKDEEILLLQE-------EREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E ++Q KDEE+L ++E E E ++ + + LL+ K E ++A
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEE 908
Query: 296 KLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEED------EGLEGEPDG 349
RL+ K + EE+ H ES E + + E+ + LE + D
Sbjct: 909 MRARLAAKK---QELEEILH----DLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD- 960
Query: 350 VEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEE 409
E+ GA + Q+ V E ++ EEE ED + + E++ + R A ++ EE
Sbjct: 961 -EEEGARQKL-QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 410 EL----LAQLEEYEQVIL-DFQFNLEAT-RTRYSLATGV-------------IASLQQQV 450
E LA++ ++V++ D + L+ +TR L IA LQ Q+
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 451 DFQETQLRKINTE---------NETLQKE-----LRERRQQLQAMTDKFSNLREDKKHQE 496
D + QL K E +ETL K +RE + Q+ + + F + + + E
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAE 1138
Query: 497 MMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQED 556
K + L +++ L+ +L LDT +Q + + + +Q + K L+E+
Sbjct: 1139 ------KQKRDLSEELEALKTELE------DTLDTTAAQQELRTKREQEVAELKKALEEE 1186
Query: 557 LQSKKEMIQQAEQHTRVALESSQSRLERLR 586
++ + IQ Q ALE +LE+ +
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAK 1216
Score = 52.0 bits (123), Expect = 2e-06
Identities = 105/521 (20%), Positives = 205/521 (39%), Gaps = 83/521 (15%)
Query: 195 CEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEE 254
C + K++ L+ + + S L +R+ E + +L+ + ++
Sbjct: 1011 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQ 1070
Query: 255 ILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQ 314
I LQ + + LK+QL K + + +++ G E L K L +++ ELQ
Sbjct: 1071 IAELQAQIDELKLQLA--KKEEELQGALARGDDETLH----KNNALKVVRELQAQIAELQ 1124
Query: 315 HWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEE------ 368
++ ++ S ++ DL EE E L+ E + DT A ++ + E+
Sbjct: 1125 EDFESEKASRNKAEKQKRDLS--EELEALKTELEDTLDTTA--AQQELRTKREQEVAELK 1180
Query: 369 -GSEEEEEEEGDRDEDSEER------ELPEEEEIPRRRASSLA------ESFEEELLAQL 415
EEE + + +D +R EL E+ E +R ++L E+ +EL ++
Sbjct: 1181 KALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV 1240
Query: 416 EEYEQVI---------LDFQFN------LEATRTRYSLATGVIASLQQQVDFQETQLRK- 459
+ +QV LD Q E R R LA + LQ ++D T L +
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA-SKLQNELDNVSTLLEEA 1299
Query: 460 -------------INTENETLQKELRERRQQLQAMTDKFSNLREDK--------KHQEMM 498
+ ++ + Q+ L+E +Q ++ + L E+K + +E
Sbjct: 1300 EKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR 1359
Query: 499 GLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQ 558
+EK L+ Q+++ ++K+ I L+ +L + E L+ + L+
Sbjct: 1360 KNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE 1419
Query: 559 SKKEMIQQ--------AEQHTRVA--LESSQSRLERL--RNKIIQATFSISGTKSLA--- 603
K +QQ + +VA LE Q + ++L K I A ++ ++ A
Sbjct: 1420 KTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAR 1479
Query: 604 -NEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSE 643
E + AL+ + + ++ Q KQ + L S+
Sbjct: 1480 EKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520
Score = 39.7 bits (91), Expect = 0.009
Identities = 24/145 (16%), Positives = 78/145 (53%), Gaps = 8/145 (5%)
Query: 447 QQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQ-EMMGLIEKDN 505
++++ ++ +L K+ + ++ EL E ++ Q + ++ + L E + + E+ E+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 506 QLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQ 565
L + ELE ++ +L+++V + +E+ ++ QN ++ + +DL+ + + +
Sbjct: 911 ARLAAKKQELEE-------ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 566 QAEQHTRVALESSQSRLERLRNKII 590
A Q ++ +++++++++ +I+
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEIL 988
Score = 32.0 bits (71), Expect = 1.9
Identities = 45/190 (23%), Positives = 78/190 (41%), Gaps = 23/190 (12%)
Query: 407 FEEELLAQLEEYEQV-ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENE 465
F +LA LEE + I D +A Y LA A QQQ L +
Sbjct: 770 FRAGVLAHLEEERDLKITDIIIFFQAVCRGY-LARKAFAKKQQQ-------LSALKVLQR 821
Query: 466 TLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCV 525
L+ R Q + K L + + +E L KD +LL+ ++ K TK +
Sbjct: 822 NCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE--LQAKDEELLK-----VKEKQTKVEGE 874
Query: 526 ISELDTKVSQLQEQVELDQNHLQ-------RWKQLQEDLQSKKEMIQQAEQHTRVALESS 578
+ E++ K QL E+ + LQ ++++ L +KK+ +++ +E
Sbjct: 875 LEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEE 934
Query: 579 QSRLERLRNK 588
+ R + L+N+
Sbjct: 935 EERNQILQNE 944
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 65.1 bits (157), Expect = 2e-10
Identities = 110/586 (18%), Positives = 240/586 (40%), Gaps = 88/586 (15%)
Query: 110 KDAASLTGFMSKMELRRVFPTHPDCPQFSTRATSMSHCGSPT-EADLSGEIDNSSETWRG 168
K+ A+L +S ME+ Q +++++ + G P+ + D+ + +T
Sbjct: 899 KEIATLKQHLSNMEV-----------QVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQ 947
Query: 169 TQDLFLARRGSDTNVDGYLLPFSKSICEFDYLRKRRKSQT------LSPVTSSSVASQSC 222
DL + S +NV+ Y + + + K T + S Q+
Sbjct: 948 VNDLKERLKTSTSNVEQY----QAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQ 1003
Query: 223 LRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSM 282
L K++ + V EK + ++ ++++ L++ +++ +++ L Q S
Sbjct: 1004 LEKKL---MEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEAL----QRAST 1056
Query: 283 SPGRREQLSDASLKLGRLSLLKAFSRHEEELQ-HWWQMQEESAAPER-GKEPDLGGGEED 340
+ +Q + ++++ +A +++E EL H ++ AA E+ K + E+
Sbjct: 1057 ALSNEQQARRDCQEQAKIAV-EAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEE 1115
Query: 341 EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPR--- 397
+ E +E +W E ++E + R ED E++ ++I +
Sbjct: 1116 TTQKAESQLLECKASW-------EERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSD 1168
Query: 398 RRASSLAESFEEELLAQLEE----YEQVILDFQF---NLEATRTRYSLATGVIASLQQQV 450
+ +S+ E + L L E EQ++ +F E TR+ +A +Q+V
Sbjct: 1169 KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRV 1228
Query: 451 DFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQ 510
+ E +L++ LQ L R+++Q + E K E M ++ + N++LR+
Sbjct: 1229 ELLERELQE-------LQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLRE 1281
Query: 511 QVSELERKLTKRDCVI--------------SELDTKVSQLQEQVELDQNHLQRWK----- 551
+ LE+ L + + +EL K LQ + +L + ++RWK
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH 1341
Query: 552 ----QLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEIS 607
Q D + ++++ + E HT+ ++ + RL+ +I ++ S++ ++L +
Sbjct: 1342 LVSQQKDPDTEEYRKLLSEKEVHTK-RIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 608 DNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKSKKG 653
E L ++ +E+ L K+ +Q+ +T K G
Sbjct: 1401 -----EDLNKVRTEKETIQKDL---DAKIIDIQEKVKTITQVKKIG 1438
Score = 55.5 bits (132), Expect = 2e-07
Identities = 90/465 (19%), Positives = 193/465 (41%), Gaps = 44/465 (9%)
Query: 201 RKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQE 260
R++R Q + S + + L+ + L++ EK + + EL+ ++ K EE+ L+E
Sbjct: 179 REKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEE 238
Query: 261 EREALKMQ-----------LKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRH 309
+ LK L L + K Q+ SM +L +A +KL +L K+ +
Sbjct: 239 QMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAHIKLS--NLYKSAADD 295
Query: 310 EEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEG 369
E + E + A E + GE ++ ++ VE + + + + G
Sbjct: 296 SEA-----KSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQS---KDQMEKEMLEKIG 347
Query: 370 SEEEEEEEGDRDEDSEERE--LPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQF 427
E+E E + + +R+ + EEE+ ++ A + + +L E ++ Q
Sbjct: 348 RLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQD 407
Query: 428 NLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSN 487
L + + + ++V+ + L++ E E QK + +L+ +
Sbjct: 408 QLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQR 467
Query: 488 LRED-KKHQEMMGLIEKDNQLLRQQVSELERKL---------TKRDCVISELDTKVSQLQ 537
L+ED K + ++E+DN+ + QV +L +++ + + VI + + + +
Sbjct: 468 LQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADIS 527
Query: 538 EQVELDQNHLQRWKQLQEDLQSKKEMI----QQAEQHTRVALESSQSRLERLRNKIIQAT 593
E+ HL ++ ++E Q + ++ + E R E++ S++ L+ K+ A
Sbjct: 528 SSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESAL 587
Query: 594 FSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQ-KGVKVP 637
+ + S ++ + I+ +R Y L Q GV +P
Sbjct: 588 TELEQLRK-----SRQHQMQLVDSIVRQRDMYRILLSQTTGVAIP 627
Score = 45.8 bits (107), Expect = 1e-04
Identities = 52/226 (23%), Positives = 93/226 (41%), Gaps = 38/226 (16%)
Query: 380 RDEDSEE-RELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSL 438
+D D+EE R+L E+E+ +R L E + E R+ SL
Sbjct: 1347 KDPDTEEYRKLLSEKEVHTKRIQQLTEEIG-----------------RLKAEIARSNASL 1389
Query: 439 ATGVIASLQQQVDFQETQLRKINTENETLQKELRER----RQQLQAMTD------KFSNL 488
Q + + L K+ TE ET+QK+L + +++++ +T ++
Sbjct: 1390 TNN-----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQ 1444
Query: 489 REDKKHQE---MMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQN 545
E+ K Q+ M + Q VS E + K +++ +TK L+ QVE Q
Sbjct: 1445 YEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKE--TLNQAETKSKSLESQVENLQK 1502
Query: 546 HLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQ 591
L + +LQ + +Q R L+ ++ E+LR +I +
Sbjct: 1503 TLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITE 1548
Score = 45.1 bits (105), Expect = 2e-04
Identities = 44/226 (19%), Positives = 104/226 (46%), Gaps = 26/226 (11%)
Query: 378 GDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQ-LEEYEQVILDFQFNLEATRTRY 436
G R + E +++++ A S + E+ + Q ++E ++ L T+
Sbjct: 1438 GRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKET-------LNQAETKS 1490
Query: 437 SLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLRE---DKK 493
+ +LQ+ + +ET+ R + + LQ EL RQ LQ T + LR+ +K+
Sbjct: 1491 KSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKE 1550
Query: 494 HQEMMGLIEKDNQL-----LRQQVSELERKLTKRDCVI----SELDTKVSQLQEQVELDQ 544
+ ++ +++ ++ Q+++ +L +R+ + ELD +++ L+ Q E
Sbjct: 1551 EKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRI 1610
Query: 545 NHLQR------WKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLER 584
+ L+R + L++ + ++ + EQ ++ L+++ + ER
Sbjct: 1611 SRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGER 1656
Score = 39.3 bits (90), Expect = 0.012
Identities = 60/271 (22%), Positives = 110/271 (40%), Gaps = 30/271 (11%)
Query: 380 RDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLA 439
R+ + +E + E+ + S+L E E+L + Q++ + R S
Sbjct: 564 REREEQETTSSKITELQLKLESALTEL--EQLRKSRQHQMQLVDSIVRQRDMYRILLSQT 621
Query: 440 TGVI----ASLQQQVDFQETQLRKINTENETL--------QKELRERRQQLQAMTDKFSN 487
TGV AS V T R ++ + E E + L+ + + F N
Sbjct: 622 TGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFEN 681
Query: 488 LREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHL 547
+++K E + + + L++QV++L + TK + + LQ+ VE + +
Sbjct: 682 YKKEKAENEKIQ--NEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREI 739
Query: 548 ----QRWKQLQEDLQSKKEMIQQAEQHTRVALES---SQSRLERLRN-----KIIQATFS 595
+R ++L Q ++++I Q R A E ++ R E L+ K+ + S
Sbjct: 740 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLS 799
Query: 596 ISGTKSLANEISDNDILEALQRI--ISERSD 624
LA + N +L LQ I I ERS+
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSE 830
Score = 36.6 bits (83), Expect = 0.075
Identities = 47/227 (20%), Positives = 96/227 (42%), Gaps = 24/227 (10%)
Query: 417 EYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQ 476
E EQ + + L ++ R T SL+ +++ QL+ + +N KEL +
Sbjct: 49 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKN----KELEIAQD 104
Query: 477 QLQAMTDKFSNLREDKKHQEMMGLIEKDNQL------LRQQVSELERKLTKRDCVISELD 530
+ A+ +F+ +E+ + E LI + +L L + V L KL + + EL
Sbjct: 105 RNIAIQSQFTRTKEELE-AEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQ 163
Query: 531 TKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERL----R 586
K+ +LQ D + R K+L++ +KE++ L++ L L
Sbjct: 164 LKLDELQAS---DVSVKYREKRLEQ----EKELLHSQNTWLNTELKTKTDELLALGREKG 216
Query: 587 NKIIQATFSISGTKSLANEISD--NDILEALQRIISERSDYYNQLKQ 631
N+I++ ++ K + + + N + + + + D +LK+
Sbjct: 217 NEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 64.7 bits (156), Expect = 3e-10
Identities = 84/384 (21%), Positives = 164/384 (42%), Gaps = 43/384 (11%)
Query: 240 CLSELEIQVQKKDEEILLLQEEREALKMQLK--------CLLKGKGQETSMSPGRREQLS 291
C E + +E+IL L++E+E L+ +L+ L K + +E + ++Q
Sbjct: 1151 CTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKD 1210
Query: 292 DASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVE 351
D ++R +E+ Q +E ++ ++ + E +G D E
Sbjct: 1211 D-------------YNRLQEQFDE--QSKENENIGDQLRQLQIQVRESIDGKLPSTDQQE 1255
Query: 352 DTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEEL 411
+ G+ + E + E + D E+ + +S+A+ +
Sbjct: 1256 SCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHS---EDASALQGGTSVAQ-----I 1307
Query: 412 LAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINT---ENETLQ 468
AQL+E E ++ + + +T + + + + LQ+Q++ Q ++ + T E E
Sbjct: 1308 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHA 1367
Query: 469 KELRERRQQLQAMTDKFSNLRE-DKKHQEMMGLI---EKDNQLLRQQVSELERKLTKRDC 524
+ L+++ + Q +LRE K E+ LI E+D L Q+SE E LTK
Sbjct: 1368 ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT 1427
Query: 525 VISELDTKVSQLQEQVELD-QNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLE 583
I E + + L Q+E+ + H +R KQLQ +L K+ ++ + +R + Q
Sbjct: 1428 EIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESR----AKQQIQR 1483
Query: 584 RLRNKIIQATFSISGTKSLANEIS 607
+L+ +I ++ KSL E+S
Sbjct: 1484 KLQAALISRKEALKENKSLQEELS 1507
Score = 62.8 bits (151), Expect = 1e-09
Identities = 89/401 (22%), Positives = 177/401 (44%), Gaps = 58/401 (14%)
Query: 242 SELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLS---DASLKLG 298
++LE+Q ++ DE I LQ E C +K K +E ++Q+ A+L +
Sbjct: 1441 TQLEMQAKEHDERIKQLQVE--------LCEMKQKPEEIGEESRAKQQIQRKLQAAL-IS 1491
Query: 299 RLSLLKAFSRHEEEL-----------QHWWQMQEESAAPERGKEPDLGG----GEEDEGL 343
R LK +EEL + ++ + +A + K+ LG EE + L
Sbjct: 1492 RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKL 1551
Query: 344 EGEPD-GVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASS 402
E D + + + + + EG E++E+ +EI ++S
Sbjct: 1552 ITEMDRSLLENQSLSSSCESLKLALEGLTEDKEK--------------LVKEIESLKSSK 1597
Query: 403 LAESFE-EELLAQLEEYEQVILDFQFNL--EATRTRYSLATGVIASLQQQVDFQETQLRK 459
+AES E +E +L++ +++L N+ EA R ++ V+ +++Q+ +LR
Sbjct: 1598 IAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQH-----VVEAVRQEKQELYGKLRS 1652
Query: 460 INTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKL 519
+ +K+L+E Q+++ M +K + K Q+ + +E++N LR +V
Sbjct: 1653 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSK--QQKILELEEENDRLRAEVHPAGD-- 1708
Query: 520 TKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALE--- 576
T ++C+ + L + S ++E++E + + + + L S+K+ + + Q + +E
Sbjct: 1709 TAKECMETLLSSNAS-MKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNV 1767
Query: 577 SSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQR 617
S Q+ LE Q + GT+S+ E + D L R
Sbjct: 1768 SKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTR 1808
Score = 58.2 bits (139), Expect = 2e-08
Identities = 99/452 (21%), Positives = 193/452 (42%), Gaps = 82/452 (18%)
Query: 219 SQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQ 278
+Q +++R+ + ++ E + + ++Q+Q+KDE LQEER+A ++K
Sbjct: 46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDE---ALQEERKAADNKIK-------- 94
Query: 279 ETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGE 338
LKL + L + +++ EE++ +
Sbjct: 95 ---------------KLKLHAKAKLTSLNKYIEEMK----------------------AQ 117
Query: 339 EDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPE--EEEIP 396
L EP E Q+ + +EEE E E + + E+ EL + ++
Sbjct: 118 GGTVLPTEPQSEE---------QLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLT 168
Query: 397 RRRASSLAESFEE-----ELLAQLEEYEQVILDFQFNLEATRTRYSLATGV---IASLQQ 448
+ +A A+S E + QL+E E+ I Q L T+ + V A +
Sbjct: 169 QAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFET 228
Query: 449 QVDFQETQLRKINTENET---LQKELRERRQQLQAMTDKFSNLRE--DKKHQEMMGLIEK 503
QV E +L ++ T+ + +Q++LR +++L+ + + D QE+ E+
Sbjct: 229 QVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTA-AEQ 287
Query: 504 DNQLLRQQVSELERK-LTKRDCVISEL-DTKVSQLQEQVELDQNHLQRWKQLQEDLQSKK 561
NQ+L QQ+ ++E + T R+ V +E ++K+ + ++E+ + L + LQE++
Sbjct: 288 RNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLS-FHNLQEEMHHLL 346
Query: 562 EMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISE 621
E +QA Q + LES S LE+ +A + L+ + + ++ A + +
Sbjct: 347 EQFEQAGQ-AQAELESRYSALEQKH----KAEMEEKTSHILSLQKTGQELQSACDALKDQ 401
Query: 622 RSDYYNQLKQKGVK-VPPLQQSEAFLTSKSKK 652
S ++ V+ +QQ E L KSK+
Sbjct: 402 NSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 433
Score = 57.8 bits (138), Expect = 3e-08
Identities = 75/386 (19%), Positives = 166/386 (43%), Gaps = 56/386 (14%)
Query: 235 HEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDAS 294
+EK+ LS Q+ KD E+ +LQEE + + + + + + T + E+ D
Sbjct: 1868 NEKNTLLS----QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1923
Query: 295 LKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGG--------GEEDEGLEGE 346
+L + + + ++ Q ++ E ++ EE + L E
Sbjct: 1924 ERL-----MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1978
Query: 347 PDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAES 406
VE S++ + E + ++E G++ E +EL +E++ ++
Sbjct: 1979 KTKVE--------SEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR 2030
Query: 407 FEEELLA---QLEEYEQVILDFQFNLEATRTRYSLAT-------GVIASLQQQVDFQETQ 456
++E++ A ++ E V + Q +LE T+ + A +AS + +D +++
Sbjct: 2031 YQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSE 2090
Query: 457 LRKINTENETLQKELRERRQQLQAMTDKFS-------------NLREDKKHQEMMGLIEK 503
++ +N L+KEL+ ++ +++ + +L+E K QE + + +
Sbjct: 2091 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRR 2150
Query: 504 DNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKE- 562
+ L + + E++ L K+ D +V QLQE ++ L + + LQ ++
Sbjct: 2151 EKVHLEETIGEIQVTLNKK-------DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDR 2203
Query: 563 MIQQAEQHTRVALESSQSRLERLRNK 588
+I +A++ R ++ QS+ E +R K
Sbjct: 2204 VIDEAKKWERKFSDAIQSKEEEIRLK 2229
Score = 57.0 bits (136), Expect = 5e-08
Identities = 78/380 (20%), Positives = 157/380 (41%), Gaps = 40/380 (10%)
Query: 243 ELEIQVQ-------KKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
ELE++V KK EE+ LQE+ ++++ L + + +++L + L
Sbjct: 1320 ELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQL 1379
Query: 296 KLGRLSLLKAFSRHEEELQHWWQMQEESAAPERG----KEPDLGGGE----EDEGLEGEP 347
++ L L+ +ELQ +EE + G KE L + E E L
Sbjct: 1380 QIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKAL 1439
Query: 348 DGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEE---IPRRRASSLA 404
+ A ++ + E E +++ E +E ++++ + + I R+ A
Sbjct: 1440 HTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEN 1499
Query: 405 ESFEEEL-LAQ--LEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKIN 461
+S +EEL LA+ +E + + D + + A G +A LQ++ D T++ +
Sbjct: 1500 KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSL 1559
Query: 462 TENETLQKELRERRQQLQAMTD------------KFSNLREDKKHQEMMGLIEKDNQLLR 509
EN++L + L+ +T+ K S + E + QE ++K+ ++L
Sbjct: 1560 LENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILL 1619
Query: 510 QQVSELERKLTKRDCVI-------SELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKE 562
Q + + + V+ EL K+ + + + LQ +Q E+++ K
Sbjct: 1620 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMR 1679
Query: 563 MIQQAEQHTRVALESSQSRL 582
+++Q + LE RL
Sbjct: 1680 KFAKSKQQKILELEEENDRL 1699
Score = 54.3 bits (129), Expect = 3e-07
Identities = 86/382 (22%), Positives = 161/382 (42%), Gaps = 47/382 (12%)
Query: 232 SVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRRE--- 288
S + E LS+ E+++ K D+ LLL+++R+ +Q K + Q T +S E
Sbjct: 859 SKVEELSQALSQKELEITKMDQ--LLLEKKRDVETLQQTIEEKDQ-QVTEISFSMTEKMV 915
Query: 289 QLSDASLKLG-RLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEP 347
QL++ LG + LK Q+ S A E KE E GL+
Sbjct: 916 QLNEEKFSLGVEIKTLKE------------QLNLLSRAEEAKKEQVEEDNEVSSGLKQNY 963
Query: 348 DGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDS---EERELPEEEEIPRRRASSLA 404
D + G +S+ HE ++E E+ R + +EL + ++L
Sbjct: 964 DEMSPAGQ---ISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLK 1020
Query: 405 ESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTEN 464
+ ++E+ E +V D + + + S + L+Q + +E +L+ I +
Sbjct: 1021 DESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDL 1080
Query: 465 ETLQKELRERRQQLQAMTDKFSNLREDKKHQ-EMMGLIEKDNQLLRQQVSELERKLTKRD 523
E E +Q QA+ + + +DK +Q +++ +NQ + Q++ + D
Sbjct: 1081 E----EKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGD 1136
Query: 524 CVISELDTKV-------------SQLQEQV-ELDQNHLQRWKQLQEDLQSKKEMI---QQ 566
V +T V +L+E++ L++ Q K+LQE L S+K ++ Q+
Sbjct: 1137 SVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQE 1196
Query: 567 AEQHTRVALESSQSRLERLRNK 588
E+H R L+ + RL+ +
Sbjct: 1197 KERHLREELKQQKDDYNRLQEQ 1218
Score = 50.8 bits (120), Expect = 4e-06
Identities = 103/495 (20%), Positives = 192/495 (38%), Gaps = 93/495 (18%)
Query: 225 KRMPWYLSVIHEKDHCLSELEIQVQKK-----DEEIL----LLQEEREALK-MQLKCLLK 274
K + L + E ++ L++Q+Q K D E+L + Q E E + +++K L+
Sbjct: 557 KELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLE 616
Query: 275 GKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDL 334
GQ+ + P S L A + + +H + EE + + G E
Sbjct: 617 DTGQDFPLMPNEE-------------SSLPAVEKEQASTEHQSRTSEEISLNDAGVELKS 663
Query: 335 GGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEE---------------EEEEEGD 379
+ D+ L PD +G H++ E +E E +
Sbjct: 664 TKQDGDKSLSAVPD-------------IGQCHQDELERLKSQILELELNFHKAQEIYEKN 710
Query: 380 RDEDSEE----RELPEEEEIPRRRASSLAESFEEE---LLAQLEEYEQV------ILDFQ 426
DE ++E +L EE + SS + EE LL+Q++E V + +
Sbjct: 711 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLE 770
Query: 427 FNL-EATRTR---YSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMT 482
NL EA R R Y T L +Q+ + + + + E LQ EL + + Q +
Sbjct: 771 MNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQS 830
Query: 483 DKFSNLREDKKHQEMMGL--------IEKDNQLLRQQVSELERKLTKRDCVISELDTKVS 534
+L+ +++E L I + L Q +S+ E ++TK D ++ E V
Sbjct: 831 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVE 890
Query: 535 QLQEQV--------ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLR 586
LQ+ + E+ + ++ QL E+ S I+ ++ + + +++ E++
Sbjct: 891 TLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVE 950
Query: 587 --NKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQL-------KQKGVKVP 637
N++ S A +IS ++ + E +L K+ +V
Sbjct: 951 EDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1010
Query: 638 PLQQSEAFLTSKSKK 652
L++ A L +SKK
Sbjct: 1011 RLEEELANLKDESKK 1025
Score = 50.1 bits (118), Expect = 7e-06
Identities = 82/445 (18%), Positives = 180/445 (40%), Gaps = 44/445 (9%)
Query: 203 RRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEE-------I 255
+RK Q ++ L++ + I L+++E QV +++E +
Sbjct: 1482 QRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRL 1541
Query: 256 LLLQEEREALKMQL-KCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQ 314
LLQEER+ L ++ + LL+ + +S SLKL L + + +E++
Sbjct: 1542 ALLQEERDKLITEMDRSLLENQSLSSSCE----------SLKLALEGLTEDKEKLVKEIE 1591
Query: 315 HWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEE 374
+ + + K +L +E E L + V + ++ V E +E++
Sbjct: 1592 SLKSSKIAESTEWQEKHKELQ--KEYEILLQSYENVSNEA-----ERIQHVVEAVRQEKQ 1644
Query: 375 E--------EEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQ 426
E E ++ + + +E +E E + + A+S ++++L EE +++ +
Sbjct: 1645 ELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVH 1704
Query: 427 FNLEATRTRYSLATGVIASLQQQVDFQETQLRKIN-------TENETLQKELRERRQQLQ 479
+ + AS++++++ + + ++ +E ++L +E+++ + Q++
Sbjct: 1705 PAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIE 1764
Query: 480 AMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQ 539
K +NL +KH + E+ Q + + E + SE
Sbjct: 1765 GNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPA 1824
Query: 540 VELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISG- 598
V D + + + KE I E+ + E SQ+ LE +N ++ + G
Sbjct: 1825 VSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT-LENEKNTLLSQISTKDGE 1883
Query: 599 TKSLANEISDNDILEALQRIISERS 623
K L E++ ++L Q+I E S
Sbjct: 1884 LKMLQEEVTKMNLLN--QQIQEELS 1906
Score = 48.5 bits (114), Expect = 2e-05
Identities = 93/500 (18%), Positives = 203/500 (40%), Gaps = 87/500 (17%)
Query: 201 RKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEI-------QVQKKDE 253
+K ++ Q L S+V + K M S+ ++D + E + +Q K+E
Sbjct: 2168 KKDKEVQQLQENLDSTVTQLAAFTKSMS---SLQDDRDRVIDEAKKWERKFSDAIQSKEE 2224
Query: 254 EILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEEL 313
EI L ++ LK +QL S+ + L + + H++++
Sbjct: 2225 EIRLKEDNCSVLK---------------------DQLRQMSIHMEELKINISRLEHDKQI 2263
Query: 314 QHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEE 373
W+ + ++ + K D GE E L +E+T SQ E ++ E
Sbjct: 2264 ---WESKAQTEVQLQQKVCDTLQGENKELL----SQLEETRHLYHSSQ-----NELAKLE 2311
Query: 374 EEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATR 433
E + +D+ ++ E+ + + + E ++ YEQ+ D Q + E T
Sbjct: 2312 SELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTS 2371
Query: 434 TRY-----------SLATG-------VIASLQQQVDFQ----ETQLRKINTENETLQKEL 471
+ SL +G IA L+QQ D + E L + EN L++E
Sbjct: 2372 RLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEEN 2431
Query: 472 RERRQQLQAMTDKFSNLREDKKHQ--------EMMGLIEKDNQLLRQQVSELERK----L 519
++ + + + ++++ Q + M ++ D + +LE + +
Sbjct: 2432 KKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII 2491
Query: 520 TKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRV-ALESS 578
++D +I E + ++L+E++ ++H+ E+ + E+IQ E +V ++ S
Sbjct: 2492 LEKDQLIQEAAAENNKLKEEIRGLRSHMDDLN--SENAKLDAELIQYREDLNQVITIKDS 2549
Query: 579 QSR----LERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGV 634
Q + ++ +NK ++ ++ K +E ++ D+ + + E+ D +++ V
Sbjct: 2550 QQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKV 2609
Query: 635 KVPPLQQSEAFLTSKSKKGT 654
+ L + +T+ ++GT
Sbjct: 2610 SISQLTRQ---VTALQEEGT 2626
Score = 47.0 bits (110), Expect = 6e-05
Identities = 94/440 (21%), Positives = 179/440 (40%), Gaps = 67/440 (15%)
Query: 230 YLSVIHEKDHCLSELEIQVQKKDEEILLLQ-------EEREALKMQLKCLLKGKGQETSM 282
+LS+I EKD + E + K EEI L+ E L +L + Q ++
Sbjct: 2487 HLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITI 2546
Query: 283 SPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEG 342
+++QL + L+ + L +++ EE+L +E A E + EE +
Sbjct: 2547 KDSQQKQLLEVQLQQNK-ELENKYAKLEEKL------KESEEANEDLRRSFNALQEEKQD 2599
Query: 343 LEGEPDGVEDTGAWGGVSQMGSVHEEGS-----------EEEEEEEGDRDEDSEER--EL 389
L E + ++ Q+ ++ EEG+ EEE S++R EL
Sbjct: 2600 LSKEIESLK-VSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAEL 2658
Query: 390 PEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQ 449
EE ++ A+ E++L +L+ + R A +A L +
Sbjct: 2659 EEELVCVQKEAAKKVGEIEDKLKKELKH-------LHHDAGIMRNETETAEERVAELARD 2711
Query: 450 VDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKH--QEMMGLIEKDNQL 507
+ E +L + EN+ L Q+Q+ S+L+ + H +E+ L K +
Sbjct: 2712 LVEMEQKLLMVTKENKGL-------TAQIQSFGRSMSSLQNSRDHANEELDELKRKYDAS 2764
Query: 508 LRQQVSELERKL--TKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMI- 564
L++ E+ L +RD ++SE ++ +E N L ++L + L SK E +
Sbjct: 2765 LKELAQLKEQGLLNRERDALLSETAFSMNSTEE------NSLSHLEKLNQQLLSKDEQLL 2818
Query: 565 ----QQAEQHTRV-----ALESSQSRLERLRNKIIQATFSISGTKSLANEISDN-----D 610
Q + + +V A+ S Q+ + L N++ + S G + A + S +
Sbjct: 2819 HLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQS 2878
Query: 611 ILEALQRIISERSDYYNQLK 630
+ +A+ + ++R +LK
Sbjct: 2879 LKKAMSSLQNDRDRLLKELK 2898
Score = 46.2 bits (108), Expect = 9e-05
Identities = 88/433 (20%), Positives = 181/433 (41%), Gaps = 64/433 (14%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDA-- 293
+K+ + E+E K E QE+ + L+ + + LL+ + S R + + +A
Sbjct: 1582 DKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSY-ENVSNEAERIQHVVEAVR 1640
Query: 294 SLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDT 353
K L++ +++E + Q E+ + K ++ + LE E E+
Sbjct: 1641 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEE---END 1697
Query: 354 GAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLA 413
V G +E E E+ E ++ E E + ++ S ++E ++ L
Sbjct: 1698 RLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM-EYETLSKKFQSLMSE--KDSLSE 1754
Query: 414 QLEEYEQVI---LDFQFNLEATRTRYSLATGVIASLQQQV--DFQETQLRKINTE----- 463
++++ + I + Q NLEAT ++ T V Q + + +E ++T
Sbjct: 1755 EVQDLKHQIEGNVSKQANLEATE-KHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSE 1813
Query: 464 --------NETLQK------ELRERRQQLQAMTDKFSNLREDK-KHQEMMGLIEKDNQLL 508
N + K E+ QQ+ + ++ + L E+K K++E +E + L
Sbjct: 1814 SVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTL 1873
Query: 509 RQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAE 568
Q+S + +L ++ E TK++ L +Q+ Q L R +L+E + +K+ ++
Sbjct: 1874 LSQISTKDGELK----MLQEEVTKMNLLNQQI---QEELSRVTKLKETAEEEKDDLE--- 1923
Query: 569 QHTRVALESSQSRLERLRNKIIQATFSISG-TKSLANEISDNDILEA----LQRIISERS 623
ERL N++ + SI + + + N++LE+ L++ +SE
Sbjct: 1924 --------------ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE 1969
Query: 624 DYYNQLKQKGVKV 636
+ QL ++ KV
Sbjct: 1970 EEKQQLVKEKTKV 1982
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/196 (23%), Positives = 89/196 (45%), Gaps = 23/196 (11%)
Query: 405 ESFEEELLAQLEEYEQVILD-------FQFNLEATRTRYSLATGVIASLQQQVDFQETQL 457
+ EE L+ + E +Q+I + + + R+ A L ++ L
Sbjct: 2481 QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDL 2540
Query: 458 RKINTENETLQKELRE-RRQQLQAMTDKFSNLRED-KKHQEMMGLIEKDNQLLRQQVSEL 515
++ T ++ QK+L E + QQ + + +K++ L E K+ +E + + L+++ +L
Sbjct: 2541 NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDL 2600
Query: 516 ERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVAL 575
+++ IS+L +V+ LQE+ L H Q L+ K+E E H AL
Sbjct: 2601 SKEIESLKVSISQLTRQVTALQEEGTLGLYHAQ--------LKVKEE-----EVHRLSAL 2647
Query: 576 -ESSQSRLERLRNKII 590
SSQ R+ L +++
Sbjct: 2648 FSSSQKRIAELEEELV 2663
Score = 34.3 bits (77), Expect = 0.37
Identities = 89/440 (20%), Positives = 183/440 (41%), Gaps = 55/440 (12%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSL 302
EL +V + +EE+ L++E + ++ L +G+ +E + E+ + + + L
Sbjct: 1004 ELLQRVSRLEEELANLKDESKK-EIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYL 1062
Query: 303 LKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQM 362
+ S E ELQH + EE A E + + + ++ L+ + + ++ A
Sbjct: 1063 KQTISEKEVELQHIRKDLEEKLAAEEQFQALVK--QMNQTLQDKTNQIDLLQA------- 1113
Query: 363 GSVHEEGSEEEEEEEGDRD-EDSEERELPEEEEIPRRRASSLAESF----EEELLAQLEE 417
+ E + ++ + D D + L +E + + +E + EE++LA +E
Sbjct: 1114 -EISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKE 1172
Query: 418 YEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKI-------NTENETLQKE 470
EQ+ Q L + + A L++++ Q+ ++ + ENE + +
Sbjct: 1173 KEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQ 1232
Query: 471 LRERRQQLQAMTD-KFSNLREDKKHQEMMGLIEKDNQLLRQQVSE--LERKLT------K 521
LR+ + Q++ D K + + + GL E + Q ++ LE L
Sbjct: 1233 LRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHS 1292
Query: 522 RDCVISELDTKVSQLQEQV-----ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALE 576
D + T V+Q++ Q+ E + L+ E + +E+ Q EQ + LE
Sbjct: 1293 EDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLE 1352
Query: 577 ---------SSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYN 627
++ E L+ K+ + I+G + L E+ L+ LQ++IS++ + +
Sbjct: 1353 IESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL-RELQPK--LDELQKLISKKEEDVS 1409
Query: 628 QLKQKGVKVPPLQQSEAFLT 647
L + L + EA LT
Sbjct: 1410 YLSGQ------LSEKEAALT 1423
Score = 32.3 bits (72), Expect = 1.4
Identities = 56/222 (25%), Positives = 92/222 (41%), Gaps = 42/222 (18%)
Query: 199 YLRKRRKSQTLSPVTSSSVASQS-CLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILL 257
Y R+ + SP S ++ ++ LR ++ L IH+K E+++Q+ +
Sbjct: 3005 YQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQK-------ELRIQQLNSNFSQ 3057
Query: 258 LQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWW 317
L EE+ L +QL C +TS S RE L ++L+
Sbjct: 3058 LLEEKNTLSIQL-C-------DTSQS--LRENQQHYGDLLNHCAVLEK------------ 3095
Query: 318 QMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEE 377
Q+QE A P + G +E G+ + D E + + SE +++
Sbjct: 3096 QVQELQAGP-LNIDVAPGAPQEKNGVHRKSDPEE----------LREPQQSFSEAQQQLC 3144
Query: 378 GDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYE 419
R E +E R+L EEE +R A+ A S EE + +LE E
Sbjct: 3145 NTRQEVNELRKLLEEER-DQRVAAENALSVAEEQIRRLEHSE 3185
Score = 32.0 bits (71), Expect = 1.9
Identities = 69/347 (19%), Positives = 123/347 (35%), Gaps = 66/347 (19%)
Query: 232 SVIHEKDHCLSELEIQVQKKDEEIL---------LLQEEREALKMQLKCLLKGKGQETSM 282
S+ + +DH EL+ +K D + LL ER+AL + + +E S+
Sbjct: 2742 SLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNST-EENSL 2800
Query: 283 SP---------GRREQLSDASLKLGRL-----SLLKAFSRHEEELQHWWQMQEESAAPER 328
S + EQL S +L S KA + + E H W E+ E
Sbjct: 2801 SHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEE 2860
Query: 329 GKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERE 388
GK+ S E S ++ D D +E
Sbjct: 2861 GKQRS------------------------AAQPSTSPAEVQSLKKAMSSLQNDRDRLLKE 2896
Query: 389 LPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQ 448
L ++ + + E L AQL+EY+ FQ E R + L+
Sbjct: 2897 LKNLQQQYLQINQEITEL--HPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRM 2954
Query: 449 QVDFQETQLRKINTEN--------------ETLQKELRERRQQLQAMTDKFSNLREDKKH 494
+ E R++ + + L +ELR Q Q + ++ +
Sbjct: 2955 EKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETS 3014
Query: 495 QEMMGL--IEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQ 539
G + + +LLR Q+++ +++ +++ I +L++ SQL E+
Sbjct: 3015 ASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEE 3061
>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
Length = 475
Score = 63.5 bits (153), Expect = 6e-10
Identities = 70/289 (24%), Positives = 132/289 (45%), Gaps = 46/289 (15%)
Query: 361 QMGSVHEEGSEEEE-EEEGDRDEDSEERELPEEEEIPRRRASSLAE-------------- 405
++G +H++ E E+ ++E + E ++L EE I +R L +
Sbjct: 74 EVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHR 133
Query: 406 ---SFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINT 462
S E L A++EE+ Q LD+ E R Y QQQV E Q + +
Sbjct: 134 EDRSEIERLTAKIEEFRQKSLDW----EKQRLIY----------QQQVSSLEAQRKALAE 179
Query: 463 ENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKR 522
++E +Q +L R+Q+L+++ L + Q + +E+ N + E+ER LT R
Sbjct: 180 QSEIIQAQLVNRKQKLESV-----ELSSQSEIQHLSSKLERANDTICANELEIER-LTMR 233
Query: 523 DCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRL 582
V + T ++ LQEQ + ++ L+ ++L E LQ +K ++ A Q + ++ +
Sbjct: 234 --VNDLVGTSMTVLQEQQQKEEK-LRESEKLLEALQEEKRELKAALQSQENLIHEARIQK 290
Query: 583 ERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQ 631
E+L+ K+ + T+ IS + +++ E + Y +LK+
Sbjct: 291 EKLQEKV-----KATNTQHAVEAISLESVSATCKQLSQELMEKYEELKR 334
>gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]
Length = 495
Score = 63.5 bits (153), Expect = 6e-10
Identities = 70/289 (24%), Positives = 132/289 (45%), Gaps = 46/289 (15%)
Query: 361 QMGSVHEEGSEEEE-EEEGDRDEDSEERELPEEEEIPRRRASSLAE-------------- 405
++G +H++ E E+ ++E + E ++L EE I +R L +
Sbjct: 74 EVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHR 133
Query: 406 ---SFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINT 462
S E L A++EE+ Q LD+ E R Y QQQV E Q + +
Sbjct: 134 EDRSEIERLTAKIEEFRQKSLDW----EKQRLIY----------QQQVSSLEAQRKALAE 179
Query: 463 ENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKR 522
++E +Q +L R+Q+L+++ L + Q + +E+ N + E+ER LT R
Sbjct: 180 QSEIIQAQLVNRKQKLESV-----ELSSQSEIQHLSSKLERANDTICANELEIER-LTMR 233
Query: 523 DCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRL 582
V + T ++ LQEQ + ++ L+ ++L E LQ +K ++ A Q + ++ +
Sbjct: 234 --VNDLVGTSMTVLQEQQQKEEK-LRESEKLLEALQEEKRELKAALQSQENLIHEARIQK 290
Query: 583 ERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQ 631
E+L+ K+ + T+ IS + +++ E + Y +LK+
Sbjct: 291 EKLQEKV-----KATNTQHAVEAISLESVSATCKQLSQELMEKYEELKR 334
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 63.2 bits (152), Expect = 8e-10
Identities = 71/350 (20%), Positives = 162/350 (46%), Gaps = 51/350 (14%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQE---EREALKMQLKCLLKGKGQETSMSPGRREQLSD 292
EK+ + LE + +K+E+I L+E E+E ++ Q + + +E + + Q +
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE----KRQEEEKIREQEKRQEQE 415
Query: 293 ASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVED 352
A + + + + E+ + W+ +E+ E+ +E + E++E E E
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ-EQEEMWRQEEKIREQ 474
Query: 353 TGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDS---EERELPEEEEIPRRRASSLAESFEE 409
W Q +HE+ ++EE+ R E+ +E ++ E+EE R+ + E +E
Sbjct: 475 EEIW---RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE--QE 529
Query: 410 ELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQK 469
E + + EE +++Q + + Q K+ + E +Q+
Sbjct: 530 EKIREQEE---------------------------KIREQEEMMQEQEEKMGEQEEKMQE 562
Query: 470 ELRERRQQLQAMTDKFSNLREDK-KHQEMMGLIEKDNQLLRQQ---VSELERKLTKRDCV 525
+ + RRQ+ + + ++ +RE K K +E I + + +R+Q + E E K+ +++
Sbjct: 563 QEKMRRQE-EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Query: 526 ISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVAL 575
+ E + K+ + +E++ + + W+Q + L+ ++E +Q+ ++H A+
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKM--WEQ-EVRLRQQEEKMQEHQEHLEAAI 668
Score = 58.2 bits (139), Expect = 2e-08
Identities = 80/416 (19%), Positives = 182/416 (43%), Gaps = 33/416 (7%)
Query: 187 LLPFSKSICEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEI 246
LLP + E D+L K + Q++S + V + + ++ + E E
Sbjct: 257 LLPQQQLQAEADHLGK--ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 247 QVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAF 306
++Q+++E+I +E+ + +++ + ++ + E + + K+ RL +
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE--EMM 372
Query: 307 SRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVH 366
EE+++ +++E+ E+ +E + EE++ E E ++ W ++
Sbjct: 373 WEKEEKIR---ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429
Query: 367 EEGSEEE-----EEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEY--E 419
E+ E+E +EE+ E E E +E+E R+ + E +EE+ Q E+ +
Sbjct: 430 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE--QEEIWRQKEKMHEQ 487
Query: 420 QVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQ 479
+ I + + + I ++++ QE ++R+ + ++++RE+ + +Q
Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ 547
Query: 480 AMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVS---ELERKLTKRDCVISELDTKV--- 533
+K E + QE M R+Q E E K+ ++ I E + K+
Sbjct: 548 EQEEKMGEQEEKMQEQEKM----------RRQEEKIREQEEKIREQKEKIREQEEKIWEQ 597
Query: 534 -SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNK 588
+++EQ E+ Q ++ + +E + ++E +Q+ E+ R E + RLR +
Sbjct: 598 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 653
Score = 55.8 bits (133), Expect = 1e-07
Identities = 84/418 (20%), Positives = 187/418 (44%), Gaps = 53/418 (12%)
Query: 215 SSVASQSCLRKRMPWYLSVIHEKDHCLS-----------ELEIQVQKKDEEILLLQEERE 263
S+VA+Q +K+ Y+ + ++ LS EL+ + K E++ L++ E+
Sbjct: 182 SAVATQ---KKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238
Query: 264 ALKMQLKCLLKGKGQETSMSPGRR---------EQLSDASLKL----------GRLSLLK 304
+++ +K L + + + P ++ ++L S KL RL+ +
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 305 AFS--RHEEELQHWWQMQEESAAPERGKEPDLGGGEE----DEGLEGEPDGV---EDTGA 355
R EE++Q W + +E R +E + EE E + E + ++
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 356 WGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFE-EELLAQ 414
W +M + EE E+EE+ + +E E+E E+E R+ + E + +E A+
Sbjct: 359 WEKEEKMRRL-EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 415 LEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRER 474
+ E+ I + + E R + + +Q +E + R+ E ++++RE+
Sbjct: 418 MWRQEEKIREQE---EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 474
Query: 475 RQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVS 534
+++ +K + +K +E + E+ +++ E E K+ +++ I E + K+
Sbjct: 475 -EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR 533
Query: 535 Q----LQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNK 588
+ ++EQ E+ Q ++ + +E +Q +++M +Q E+ R E + + E++R +
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ-EEKIREQEEKIREQKEKIREQ 590
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/223 (23%), Positives = 112/223 (50%), Gaps = 27/223 (12%)
Query: 381 DEDSEER--ELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSL 438
DE+ +E+ +L E+ ++ S + + +E L +LE + ++ Q EA L
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKE-LKRKLERAKLLLPQQQLQAEADHLGKEL 274
Query: 439 ATGVIASLQQQVDFQET-------QLRKINTENETLQK---ELRERRQQLQAMTDKFSNL 488
+ V A LQ QV+ E Q K+ + E +Q+ +++E+ ++++ +K
Sbjct: 275 QS-VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 489 REDKKHQEMMGLIEKDNQLLRQQ--VSELERKLTKRDCVISELDTKVSQLQEQVELDQNH 546
E + QE M + EK+ ++ RQ+ + E E K+ + + ++ E + K+ +L+E++ H
Sbjct: 334 EEKMRRQEEM-MWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM-----H 387
Query: 547 LQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKI 589
Q + QE+ + ++E I++ E+ + ++++ R KI
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKR-----QEQEAKMWRQEEKI 425
Score = 38.1 bits (87), Expect = 0.026
Identities = 51/268 (19%), Positives = 122/268 (45%), Gaps = 35/268 (13%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDA 293
I E++ + E E ++ +++E+I ++ RE K Q + +E + + +
Sbjct: 425 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ-------EQEEMWRQEEKIREQEEI 477
Query: 294 SLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDT 353
+ ++ + + EE++ W Q ++ E+ +E + ++E + + + + +
Sbjct: 478 WRQKEKMHEQEKIRKQEEKV--WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 354 GAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERE-LPEEEEIPRRRASSLAESFEEELL 412
+ EE +E+EE+ G+++E +E+E + +EE R + + E E
Sbjct: 536 ------EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE---- 585
Query: 413 AQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELR 472
++ E E+ I + + E R + + +Q+Q + Q K+ + E +Q++
Sbjct: 586 -KIREQEEKIWEQE---EKIREQEEM-------MQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Query: 473 ERRQQLQAMTDKFSNLRED----KKHQE 496
+ R+Q + M ++ LR+ ++HQE
Sbjct: 635 KMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 63.2 bits (152), Expect = 8e-10
Identities = 79/351 (22%), Positives = 143/351 (40%), Gaps = 54/351 (15%)
Query: 249 QKKDEEILLLQEE---REALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKA 305
Q++DEE+ ++E RE + + + L KG ET P + L+L R +
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 306 FSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSV 365
+ E +Q +EE E K + EE++ E EP
Sbjct: 227 QQQRRERQDRVFQEEEEK---EWRKRETVLRKEEEKLQEEEPQ---------------RQ 268
Query: 366 HEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDF 425
E EEE+ + +R E ER+ E+++ RR L EEE Q EE
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE-------- 320
Query: 426 QFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTE--NETLQKELRERRQQLQAMTD 483
E R +QQ + +E QLR+ E + L++E E R++ Q +
Sbjct: 321 --RREQQERR-----------EQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 484 KFSNLREDKKHQEMM----------GLIEKDNQLLRQQVSELERKLTKRDCVISELDTKV 533
+ RE + +E + ++ QL R+Q E++L + + E +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 534 SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLER 584
Q +E+ E +R ++L+ + + +++ +++ E+ R E + +L+R
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Score = 62.4 bits (150), Expect = 1e-09
Identities = 87/373 (23%), Positives = 161/373 (43%), Gaps = 63/373 (16%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSL 302
ELE Q ++++E L QEE + L+ + QE R+ + L+ +
Sbjct: 1165 ELERQYREEEE---LQQEEEQLLREE---------QEKRRQERERQYREEEELQRQKRKQ 1212
Query: 303 LKAFSRHEEELQHWWQMQEESAAPE-----RGKEPDLGGGEEDE---------------G 342
+L+ W+ ++E+A + +G+E + ED G
Sbjct: 1213 RYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLG 1272
Query: 343 LEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERE--LPEEEEIPRRRA 400
+ E D ++ W + E+ EE++E RD S+E + L EE E RRR
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 401 SSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKI 460
+ + EEE L L+E E+ L Q R ++++ QE Q RK
Sbjct: 1333 ETDRKFREEEQL--LQEREEQPLRRQERDRKFR-------------EEELRHQE-QGRKF 1376
Query: 461 NTENETLQKELRERR-----QQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSEL 515
E + L+++ RER+ QQL+ ++ LR+D+ + E++ QL RQ E
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQ-EREQQLRQDRDRK----FREEEQQLSRQ---ER 1428
Query: 516 ERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVAL 575
+RK + + + + + L+E+ +L Q +++++ ++ LQ ++E ++ R L
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488
Query: 576 ESSQSRLERLRNK 588
E Q + R++
Sbjct: 1489 EEEQQLRRQERDR 1501
Score = 60.8 bits (146), Expect = 4e-09
Identities = 79/332 (23%), Positives = 138/332 (41%), Gaps = 43/332 (12%)
Query: 277 GQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWW-----QMQEESAAPERGK- 330
GQ T + +R + G+ SLL+ R +EE Q + Q++EE R K
Sbjct: 90 GQATGLDEEKRARCD------GKESLLQ--DRRQEEDQRRFEPRDRQLEEEPGQRRRQKR 141
Query: 331 ---EPDLGGGEED----EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDED 383
E +L GEE E LE D W Q E EEE+ +
Sbjct: 142 QEQERELAEGEEQSEKQERLEQRDRQRRDEELW---RQRQEWQEREERRAEEEQLQSCKG 198
Query: 384 SEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVI 443
E E P+EE++ RR L EE Q E + + + E R R ++
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE-WRKRETVLRKEE 257
Query: 444 ASLQQQ-------VDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQE 496
LQ++ + +E QLRK+ E + L++E +E QQ Q + + R+ ++ +
Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 497 MMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQED 556
++ Q R+Q E + +R+ + + ++Q+ +Q +R +QL+ +
Sbjct: 316 EQQEERREQQERREQQEERREQQLRRE--------QEERREQQLRREQEEERREQQLRRE 367
Query: 557 LQSKKEMIQQAEQHTRVALESSQSRLERLRNK 588
Q ++ QQ + ++ E R ++LR +
Sbjct: 368 -QEEERREQQLRREQQLRREQQLRREQQLRRE 398
Score = 60.8 bits (146), Expect = 4e-09
Identities = 77/361 (21%), Positives = 154/361 (42%), Gaps = 40/361 (11%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E+D E E QV++++ E L+EE++ + + + +E + R EQ
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF----REEEQLLQEREEQ------ 1476
Query: 296 KLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGA 355
+L R + F E++L+ + ++ R +EP+ EE++ L +
Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ--------- 1527
Query: 356 WGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFE------- 408
+ +E + +E G + +R+ EEE++ + R E
Sbjct: 1528 ----QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
Query: 409 EELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDF----QETQLRKINTEN 464
EE + +E E+ ++ + L + L ++ +E QL + +
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643
Query: 465 ETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDC 524
+ L++E + RRQ+ + + + R+ K +E L E + Q LR+Q E +RK + +
Sbjct: 1644 KFLEEEPQLRRQERE---QQLRHDRDRKFREEEQLLQEGEEQQLRRQ--ERDRKFREEEQ 1698
Query: 525 VISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQ-QAEQHTRVALESSQSRLE 583
+ + + LQE+ +L + L+R + +E L+ + E Q + ++ R LE Q R E
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 584 R 584
R
Sbjct: 1759 R 1759
Score = 59.7 bits (143), Expect = 8e-09
Identities = 88/381 (23%), Positives = 166/381 (43%), Gaps = 72/381 (18%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDA--------- 293
+L + Q++ E+ L +EE E L+ +LK + + +E ++ +EQ +
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705
Query: 294 ----SLKLGRLSLLKAFSR-HEEELQHWWQMQEESAAPERGKEPDLGGGEEDEG---LEG 345
S R S K +SR ++E Q Q QEE R +E +L EE+ +
Sbjct: 706 WQLESEADARQS--KVYSRPRKQEGQRRRQEQEEK---RRRRESELQWQEEERAHRQQQE 760
Query: 346 EPDGVEDTGAWG-------GVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRR 398
E + T W G ++ + + E + + + E+R LPEEEE +R
Sbjct: 761 EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820
Query: 399 RASSLAESFEEELL------------AQLEEYEQVILD---------------FQFNLEA 431
R E + L QL+E E + + +++ LE
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE 880
Query: 432 TRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLRED 491
R R +LQ+Q+ +E QL + E E LQ+E RE+R++ + ++
Sbjct: 881 ERKRRRHTLYAKPALQEQLR-KEQQL--LQEEEEELQREEREKRRRQE----------QE 927
Query: 492 KKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWK 551
++++E L +++ QLLR++ + R+ +R D K+ Q +EQ+ ++ +R +
Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQERERQ---YRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 552 QLQEDLQSKKEMIQQAEQHTR 572
+ ++ + ++E+ Q+ EQ R
Sbjct: 985 EREKKYREEEELQQEEEQLLR 1005
Score = 58.2 bits (139), Expect = 2e-08
Identities = 92/417 (22%), Positives = 172/417 (41%), Gaps = 57/417 (13%)
Query: 245 EIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLK 304
E Q++++ EE Q+ R +++ + L+ + Q RREQ +L R L+
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 305 A---FSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQ 361
R +EE +H + ++E +E + E + L+ E E+T +
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQE----ERRDWLKRE----EETERHEQERR 472
Query: 362 MGSVHEEGSEEEEE-----EEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLE 416
+ + EE E EE +R E E RE E RR L EEE L Q
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 417 EYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQ 476
EQ Q E R L L+++ + + Q R+ + L++E ERR
Sbjct: 533 RSEQ-----QLRREQEERREQL-------LKREEEKRLEQERR----EQRLKREQEERRD 576
Query: 477 QLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQL 536
QL RE+++ Q+ +L R+Q LE++L + + E + + Q
Sbjct: 577 QLLK--------REEERRQQ---------RLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 537 QEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSI 596
++ E ++ Q+ + +E + +++ +++ +Q R + ERL ++ +
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 597 SGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKSKKG 653
+ LA E + +A +RI S + QL+ + +QS+ + + ++G
Sbjct: 680 RREQELAEEEQE----QARERIKSRIPKWQWQLESEA----DARQSKVYSRPRKQEG 728
Score = 57.4 bits (137), Expect = 4e-08
Identities = 77/351 (21%), Positives = 150/351 (42%), Gaps = 43/351 (12%)
Query: 242 SELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKG--QETSMSPGRREQLSDASLKLGR 299
SEL+ Q +++ +E+R Q + K + Q S P REQ R
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 300 LSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGV 359
+ F EEE +E+ R +E +L EE+E L+
Sbjct: 804 QQREQRFLPEEEE-------KEQRRRQRREREKELQFLEEEEQLQRRER----------- 845
Query: 360 SQMGSVHEEGSEEEEEEEGDRDEDSEER-ELPEEEEIPRRRASSLAESFEEELLAQLEEY 418
+Q E+G +E++E +++ +++ EEE RRR + A+ +E QL +
Sbjct: 846 AQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE---QLRKE 902
Query: 419 EQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERR--- 475
+Q++ + + L+ +++ Q+ + + + E E +++ RER+
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Query: 476 ---------QQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVS-----ELERKLTK 521
Q L +K +KK++E L +++ QLLR++ E ER+ K
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 522 RDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTR 572
+D + E + + + +E+ L + +R + +E+LQ ++E + E+ TR
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQER--ERQYREEEELQQEEEQLLGEERETR 1071
Score = 55.5 bits (132), Expect = 2e-07
Identities = 85/358 (23%), Positives = 149/358 (41%), Gaps = 49/358 (13%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPG-RREQLSDASLKLGRLS 301
E+E Q++ E L +EE E + Q LLK + QE RREQ +L R
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQ--LLKSEEQEERRQQQLRREQQERREQRLKR-- 661
Query: 302 LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQ 361
EE L+ + + E E +E +L E+++ E + W S+
Sbjct: 662 -----EEEEERLEQRLKREHE----EERREQELAEEEQEQARERIKSRIPKW-QWQLESE 711
Query: 362 MGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQV 421
+ + ++EG +R E+EE RRR S L EE Q +E EQ
Sbjct: 712 ADARQSKVYSRPRKQEG-------QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Query: 422 ILDFQFNLEAT------RTRYSLATGVIASLQQQVDFQETQLRKIN-----TENETLQKE 470
DF + +A R R S + ++Q+ +E Q R+ E E +++
Sbjct: 765 -RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Query: 471 LRERRQQLQAMTDKFSNLREDKKHQ--EMMGLIEKDNQLLRQQVSELERKLTKRDCVISE 528
RER ++LQ + ++ R ++ Q E +++D + R Q ++K
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW------- 876
Query: 529 LDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLR 586
QL+E+ + ++ L LQE L+ +++++Q+ E+ + + R E+ R
Sbjct: 877 ------QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER 928
Score = 55.1 bits (131), Expect = 2e-07
Identities = 90/379 (23%), Positives = 157/379 (41%), Gaps = 50/379 (13%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRRE-----QLSDASLKL 297
E E+Q QK+ + +++R LK Q + + ++ + RE QL D+ L+
Sbjct: 1202 EEELQRQKRKQRYRD-EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR- 1259
Query: 298 GRLSLLKAFSRHEEELQHWWQMQEESAAPE---RGKEPDLGGGEEDEGLEGEPDGVEDTG 354
+ +++LQH Q+E + R ++ D EE++ LE E
Sbjct: 1260 --------DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ-LEREEQKEAKRR 1310
Query: 355 AWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQ 414
+ + EE E+ +E DR EE+ L E EE P RR + EEEL Q
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 415 --------------LEEYEQVILDFQFNLEATRTRYSLATG---VIASLQQQVDFQETQL 457
+E E+ L + L L +QQ+ QE
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD- 1429
Query: 458 RKINTENETLQKELRERR---QQLQAMTDKFSNLRED-----KKHQEMMGLIEKDNQLL- 508
RK E + ++++ RER+ ++ Q ++ RE+ ++ ++ + E+D + L
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 509 -RQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEM--IQ 565
QQ+ ER R+ + + + L+E+ +L + QR K LQE+ Q +++ Q
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR-KFLQEEQQLRRQERGQQ 1548
Query: 566 QAEQHTRVALESSQSRLER 584
+ + R E Q R ER
Sbjct: 1549 RRQDRDRKFREEEQLRQER 1567
Score = 54.7 bits (130), Expect = 3e-07
Identities = 82/363 (22%), Positives = 152/363 (41%), Gaps = 41/363 (11%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSL 302
ELE Q +K++E L QEE + L+ + + K + QE E+L +L R
Sbjct: 1075 ELERQYRKEEE---LQQEEEQLLREEPE---KRRRQERERQCREEEELQQEEEQLLREER 1128
Query: 303 LKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQM 362
K R +EL+ ++ +EE EE++ L EP+ + +
Sbjct: 1129 EK---RRRQELERQYREEEEVQQ------------EEEQLLREEPEKRRRQE----LERQ 1169
Query: 363 GSVHEEGSEEEEE---EEGDRDEDSEERELPEEEEIPR--RRASSLAESFEEELLAQLE- 416
EE +EEE+ EE ++ ER+ EEEE+ R R+ E +L Q E
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP 1229
Query: 417 EYEQVILDFQFNLEATRTRY--SLATGVIASLQQQVDFQET--QLRKINTENETLQKELR 472
E E + D + + L + Q Q D Q + ++ + E E + + R
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
Query: 473 ERR----QQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISE 528
+R +QL+ K + R+ K +E L E+ + R+Q E +RK + + ++ E
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ--ETDRKFREEEQLLQE 1347
Query: 529 LDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNK 588
+ + + QE+ + R ++ +++ +++ E+ + E Q R + +
Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Query: 589 IIQ 591
+ Q
Sbjct: 1408 LRQ 1410
Score = 52.4 bits (124), Expect = 1e-06
Identities = 84/383 (21%), Positives = 157/383 (40%), Gaps = 35/383 (9%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E++ L E E Q + E EE + L+ Q + + + S P R+ +
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK--FLEEEQ 1522
Query: 296 KLGRLSLLKAFSRHEEELQHWWQMQ-----------EESAAPERGKEPDLGGGEEDEGLE 344
+L R + F + E++L+ + Q EE + +E L E D
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 345 GEPDGVE-DTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSL 403
E V + + + +++ +E DR +E+ L E EE R
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 404 AESFEEELLAQLEEYEQVIL---DFQFNLEATRTRYSLATGVIASLQQQ-----VDFQET 455
+ EEE + +E EQ + D +F E L G L++Q +E
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREE----EQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 456 QLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEK-----DNQLLRQ 510
QLR+ E + LQ+E + RRQ+L+ + LR++ + QE + E+ + + LR
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE-QEQLRRQERYRKILEEEQLRP 1757
Query: 511 QVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKE--MIQQAE 568
+ E + + +RD E + ++ Q +E+ +L R + +E L+ ++E ++ +
Sbjct: 1758 EREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ 1816
Query: 569 QHTRVALESSQSRLERLRNKIIQ 591
+ + E Q +LE ++ Q
Sbjct: 1817 RDGKYRWEEEQLQLEEQEQRLRQ 1839
Score = 49.7 bits (117), Expect = 9e-06
Identities = 69/371 (18%), Positives = 153/371 (41%), Gaps = 12/371 (3%)
Query: 223 LRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSM 282
L++ P + E++ L +LE Q +++ + Q++R + QL+ K + +
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR--RKQEEERREQ 317
Query: 283 SPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEG 342
RREQ + R + R E+E + Q++ E E +E L +E+E
Sbjct: 318 QEERREQQERREQQEERR---EQQLRREQEERREQQLRREQE--EERREQQLRREQEEER 372
Query: 343 LEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASS 402
E + + + + + E E++ + E++L E+++ R +
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 403 LAES-FEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKIN 461
E E+E Q + EQ E R+ + Q + + + K+
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492
Query: 462 TENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTK 521
E Q+E RE++ + + + L+ ++ + + + + QL R+Q E+ L +
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 522 RDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTR----VALES 577
+ E + + +L+ + E ++ L + ++ + + K+E ++ EQ + LE
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 578 SQSRLERLRNK 588
+ R +RL+ +
Sbjct: 613 EERREQRLKRE 623
Score = 49.3 bits (116), Expect = 1e-05
Identities = 80/346 (23%), Positives = 141/346 (40%), Gaps = 31/346 (8%)
Query: 247 QVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAF 306
++Q+K+E+ LL EE E + Q + K +E + + L + K R + +
Sbjct: 965 KLQQKEEQ--LLGEEPEKRRRQER--EKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 307 SRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVH 366
+ +E Q Q+ E R +E + EE+E L+ E + + +G
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEE-LQQEEEQL-----------LGEER 1068
Query: 367 EEGSEEEEEEEGDRDED--SEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILD 424
E +E E + ++E+ EE +L EE RRR + EEE L Q EE
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEE------- 1121
Query: 425 FQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDK 484
Q E R +++V +E QL + E Q+ R+ R++ + ++
Sbjct: 1122 -QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 485 FSNLRE--DKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQL--QEQV 540
LRE +K+ QE ++ +L RQ+ + R +R + + + + +V
Sbjct: 1181 EQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240
Query: 541 ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLR 586
++++QL ED Q + QQ QH + ER R
Sbjct: 1241 YCKGRENEQFRQL-EDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Score = 49.3 bits (116), Expect = 1e-05
Identities = 79/361 (21%), Positives = 152/361 (42%), Gaps = 45/361 (12%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
++D E E Q+++E+ L QE +++ + + + + + M ++ + +
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ 1611
Query: 296 KLGRLSLLKAFSRHEEELQHWWQMQEESAAPERG---KEPDLGGGEEDEGLEGEPDGV-- 350
+L R + F E+ LQ + Q +R +EP L E ++ L + D
Sbjct: 1612 QL-RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 351 -EDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESF-E 408
E+ G Q E + EEE+ R ++ E + L EE+++ R+ L F E
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE---LERKFRE 1727
Query: 409 EELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQ 468
EE L Q E EQ+ R ++ Q + + +E QLR+ + + +
Sbjct: 1728 EEQLRQETEQEQL------------RRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Query: 469 KE-LRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVIS 527
+E LR+ R++ Q + + D+K +E + LRQ+ E + + +R
Sbjct: 1776 EEQLRQEREEQQLRSQE-----SDRKFRE--------EEQLRQEREEQQLRPQQR----- 1817
Query: 528 ELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRN 587
D K +EQ++L++ QR +Q ++ +E E+ R E Q ++ R
Sbjct: 1818 --DGKYRWEEEQLQLEEQE-QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874
Query: 588 K 588
+
Sbjct: 1875 E 1875
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/398 (22%), Positives = 170/398 (42%), Gaps = 45/398 (11%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
EK+ E E Q+Q++ E LQEE + L+ + + + QE R QL +
Sbjct: 828 EKELQFLEEEEQLQRR-ERAQQLQEEEDGLQEDQE---RRRSQEQRRDQKWRWQLEEERK 883
Query: 296 KLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGA 355
+ R L A +E+L+ Q+ +E + +E + +E E E + ++
Sbjct: 884 R--RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE 941
Query: 356 WGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERE--LPEEEEIPRRRASSLAESFEEELLA 413
+ E+ +E E + +D+ +++E L EE RRR + EEE L
Sbjct: 942 ----QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 414 QLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRE 473
Q E EQ++ + E + R +Q+ + Q + ++ E E L +E RE
Sbjct: 998 Q--EEEQLLRE-----EREKRR-----------RQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 474 RRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKV 533
+R+ LQ ++ E++ QE L+ ++ + R+Q ELER+ K + EL
Sbjct: 1040 KRR-LQERERQYRE--EEELQQEEEQLLGEERETRRRQ--ELERQYRKEE----ELQ--- 1087
Query: 534 SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQAT 593
QE+ +L + ++ ++ + + Q ++E Q E+ + E + R + L + +
Sbjct: 1088 ---QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 594 FSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQ 631
+ L E + + L+R E + + +Q
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Score = 38.5 bits (88), Expect = 0.020
Identities = 60/282 (21%), Positives = 108/282 (38%), Gaps = 31/282 (10%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASL 295
E+D E E Q+++++ E L + + + + L +G+ Q+ R Q D
Sbjct: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL------RRQERDRKF 1693
Query: 296 KLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGA 355
+ L + R + LQ Q++ + + +E L E E L +
Sbjct: 1694 REEEQQLRRQ-ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE-------- 1744
Query: 356 WGGVSQMGSVHEEGSEEEEEEEGDRDED-----SEERELPEEEEIPRRRASSLAESFEEE 410
+ EE E EE+ R ++ EE +L +E E + R+ F EE
Sbjct: 1745 ----RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 411 LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENE--TLQ 468
+ E EQ Q + +Y + +Q+ ++ + R+ E + T +
Sbjct: 1801 EQLRQEREEQ-----QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 469 KELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQ 510
K RE ++ Q K RE K +E + +K+ Q RQ
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 62.8 bits (151), Expect = 1e-09
Identities = 55/291 (18%), Positives = 134/291 (46%), Gaps = 21/291 (7%)
Query: 371 EEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLE 430
E E+ + RD + E+ +E + +R + EELL ++ + +++ + +
Sbjct: 692 EREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQED 751
Query: 431 ATRTRYSLATGVIASLQQQVDFQETQLRKI----NTENETLQKELRERRQQLQAMTDKFS 486
R R T + +L+++V + ++ K+ + E + L++ + E + ++ + + +
Sbjct: 752 LLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSN 811
Query: 487 NLREDKKHQEM-MGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQN 545
+D+ EM + L++++N+ L+ + ELER+ V+QLQ Q+E +
Sbjct: 812 TSEQDQAGTEMRVKLLQEENEKLQGRSEELERR--------------VAQLQRQIEDLKG 857
Query: 546 HLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANE 605
+ K+ + + + +++A H R + + S L N++ A ++S T +
Sbjct: 858 DEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQ 917
Query: 606 ISD--NDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKSKKGT 654
+S+ + E +++ +++ N+ G + LQ+ A + S+ T
Sbjct: 918 LSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTST 968
Score = 52.8 bits (125), Expect = 1e-06
Identities = 97/455 (21%), Positives = 191/455 (41%), Gaps = 59/455 (12%)
Query: 198 DYLRKRRKSQT-----LSPVTSSSVASQSCLRKRMPWYLSVIHEK-DHCLSELEIQVQKK 251
D LRKR + T L SS L+++ L + E + +E+ +
Sbjct: 751 DLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRS 810
Query: 252 DEEILLLQEEREALKMQLKCL------LKGKGQETSMSPGR-REQLSDASLKLGRLSLLK 304
+ ++++ +M++K L L+G+ +E + + Q+ D LK +
Sbjct: 811 NTS----EQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIED--LKGDEAKAKE 864
Query: 305 AFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGS 364
++E E++ EE+ R +E + LE E + + G +SQ
Sbjct: 865 TLKKYEGEIRQL----EEALVHARKEEKEAVSARR--ALENELEAAQ-----GNLSQTTQ 913
Query: 365 VHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILD 424
++ SE+ +EE ++ + R L E E R E ++E+ +E L+
Sbjct: 914 EQKQLSEKLKEES---EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLE 970
Query: 425 FQFNLEA--TRTRYSLATGVIASLQQQVDFQETQLR--KINTENETLQKELRE-RRQQLQ 479
Q L+ + R LA ++ ++ ++++L K+ E +++ELR+ +R Q +
Sbjct: 971 LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDE 1030
Query: 480 AMTDKF---SNLREDKKHQEMMGLIEKDNQLLRQQ----VSELERKLTKRDCVISELDTK 532
A+T + L++ + E ++ D L +Q VS+LE +L + L +
Sbjct: 1031 ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSER 1090
Query: 533 VSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQA 592
+S+ +EQ+E +N L + + ++DL+ K ++LE + L+++II
Sbjct: 1091 ISRSREQMEQLRNELLQERAARQDLECDK-----------ISLERQN---KDLKSRIIHL 1136
Query: 593 TFSISGTKSLANEISDNDILEALQRIISERSDYYN 627
S +K + I E R+ SE D N
Sbjct: 1137 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRAN 1171
Score = 49.7 bits (117), Expect = 9e-06
Identities = 55/214 (25%), Positives = 99/214 (46%), Gaps = 25/214 (11%)
Query: 384 SEERELPEEEEIPRRRASSLAESFEEELLAQL---EEYEQVILDFQFNLEATRTRYSLAT 440
SE ++L E++ + L + E+ Q EE E++ + NLE R++++
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERM----RANLEELRSQHNEKV 662
Query: 441 GVIASLQQQVDFQETQLRK-------INTENETLQKELRERRQQLQAMTDKFSNLREDKK 493
++LQQ+++ E +LRK + E E Q E+R+ + QL M D+ + + +
Sbjct: 663 EENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKR-SE 721
Query: 494 HQEMMGLIE------KDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHL 547
+E LIE +D Q L E E L KR+ EL L+E+V +
Sbjct: 722 DREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRE---RELTALKGALKEEVSSHDQEM 778
Query: 548 QRWK-QLQEDLQSKKEMIQQAEQHTRVALESSQS 580
+ K Q +LQ+ +E +++A ++ V S +
Sbjct: 779 DKLKEQYDAELQALRESVEEATKNVEVLASRSNT 812
Score = 40.8 bits (94), Expect = 0.004
Identities = 55/260 (21%), Positives = 117/260 (45%), Gaps = 24/260 (9%)
Query: 310 EEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEG 369
EEEL+ + + Q+E+ + E L E + LE + +D V QM +
Sbjct: 1018 EEELRDYQRAQDEALTKRQLLEQTLKDLEYE--LEAKSHLKDDRSRL--VKQMEDKVSQL 1073
Query: 370 SEEEEEEEGDRD-------EDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVI 422
E EEE + D E+ E E + R A E + L Q ++ + I
Sbjct: 1074 EMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRI 1133
Query: 423 LDFQFNLEATRTRYSLATGV-IASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAM 481
+ + + +++ + IA L+ +++ +E + N L+++++E Q+
Sbjct: 1134 IHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD-- 1191
Query: 482 TDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE 541
D+ +L D+K Q + L + +++QV E E ++ + + +L +L+EQ++
Sbjct: 1192 -DEHLSLT-DQKDQLSLRL-----KAMKRQVEEAEEEIDRLESSKKKLQR---ELEEQMD 1241
Query: 542 LDQNHLQRWKQLQEDLQSKK 561
++++ + +++DL+ KK
Sbjct: 1242 MNEHLQGQLNSMKKDLRLKK 1261
Score = 36.6 bits (83), Expect = 0.075
Identities = 54/285 (18%), Positives = 123/285 (43%), Gaps = 22/285 (7%)
Query: 234 IHEKDHCLSELEIQVQKKDEEILLLQEE-REALKMQLKCLLKGKGQETSMSPGRREQLSD 292
+ EK + + K +E+ L++EE R+ + Q + L K + E ++ E +
Sbjct: 993 LKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAK 1052
Query: 293 ASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVED 352
+ LK R L+K +L+ +++EE + E E+ E L E +++
Sbjct: 1053 SHLKDDRSRLVKQMEDKVSQLE--MELEEERNNSDLLSERISRSREQMEQLRNEL--LQE 1108
Query: 353 TGAWGGVS-------------QMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRR 399
A + + +H EGS +E ++ EL + E R
Sbjct: 1109 RAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERD 1168
Query: 400 ASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRK 459
++L S L +++E + D +L + + SL + ++++QV+ E ++ +
Sbjct: 1169 RANLQLS-NRRLERKVKELVMQVDDEHLSLTDQKDQLSLR---LKAMKRQVEEAEEEIDR 1224
Query: 460 INTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKD 504
+ + + LQ+EL E+ + + + +++++D + +++ + D
Sbjct: 1225 LESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLDD 1269
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 62.4 bits (150), Expect = 1e-09
Identities = 92/465 (19%), Positives = 202/465 (43%), Gaps = 54/465 (11%)
Query: 201 RKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQE 260
+ +++ Q + S+ A + + L I +KD + LE +QK E I LL++
Sbjct: 485 KTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEK 544
Query: 261 EREALKMQLKCLLKGKGQETSMSPGR------REQLSDASLKLGRLSLLKAFSRHEEELQ 314
ERE L +++ G+G+ ++ + +EQ++ + KL S ++ + +E L
Sbjct: 545 EREDLYAKIQA---GEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQS--ESHKQAQENLH 599
Query: 315 HWWQMQEES----AAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGS 370
Q+QE+ AA +R + E + L + V + E +
Sbjct: 600 D--QVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 371 EEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLE 430
+ + + D+ + L ++++ + + L +++ A+L++ ++ + +L+
Sbjct: 658 KTAQRADLQNHLDTAQNALQDKQQELNKITTQL-----DQVTAKLQDKQEHCSQLESHLK 712
Query: 431 ATRTRYSLATGVIASLQQQVDFQETQLRKINTEN----ETLQKELRERRQQLQAMTDKFS 486
+ +Y SL+Q+ + E Q++K+ ++ + ++ L++ +QQ Q TD
Sbjct: 713 EYKEKY-------LSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLEL 765
Query: 487 NLREDKKHQEMMGLIEKDNQLLRQQVSEL-------------ERKLTKRDCVISELDTKV 533
E K EM I +L Q+ SE E+++ K+D +TK+
Sbjct: 766 RATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKI 825
Query: 534 --SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQ 591
+L +++ LQ+ K +E L ++ ++ +L++S+S E+ K
Sbjct: 826 QHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKA 885
Query: 592 ATFSISGT-KSLANEIS---DNDILE--ALQRIISERSDYYNQLK 630
A + T K L +++ +N + E L++ + + + +QLK
Sbjct: 886 AILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLK 930
Score = 57.4 bits (137), Expect = 4e-08
Identities = 68/308 (22%), Positives = 135/308 (43%), Gaps = 34/308 (11%)
Query: 371 EEEEEEEGDRDEDSEERELPEEE-EIPRRRASSLAESFEEELLA--QLEEYEQVILDFQF 427
+ EE+E+ SE +L + E R+ + E+ L+ +L + EQ + D Q
Sbjct: 401 QREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQL 460
Query: 428 NLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSN 487
L + LQ Q+D + Q ++ ++ +LRE + L+ + + +
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGD 520
Query: 488 LREDKKHQEMMGLIEKDNQ---LLRQQVSELERKLTKRD---CVISELDTKVSQLQEQVE 541
+D+K Q + L++K + LL ++ +L K+ + V+++L K LQEQV
Sbjct: 521 --KDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVT 578
Query: 542 LDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKS 601
QL E L+++ E +QA+++ ++ ++ L +++++ S++ S
Sbjct: 579 ----------QLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNS 628
Query: 602 LANE----ISDNDI---------LEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTS 648
NE +S DI L A ++R+D N L + QQ +T+
Sbjct: 629 QLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITT 688
Query: 649 KSKKGTSK 656
+ + T+K
Sbjct: 689 QLDQVTAK 696
Score = 53.1 bits (126), Expect = 8e-07
Identities = 73/358 (20%), Positives = 163/358 (45%), Gaps = 26/358 (7%)
Query: 242 SELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLS 301
SE E + QK IL L++ + LK QL+ ++ +E E+ +AS +L +L
Sbjct: 874 SEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQL-KLE 932
Query: 302 LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQ 361
L + +E+L +Q ++ + KE G +E + + A G +
Sbjct: 933 L----NSMQEQL-----IQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELK 983
Query: 362 MGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFE--EELLAQLEE-- 417
+ + + E + +++ + +EL E+E + S L ++E +E QL+
Sbjct: 984 IAVLQKTELENKLQQQLTQ----AAQELAAEKE----KISVLQNNYEKSQETFKQLQSDF 1035
Query: 418 --YEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERR 475
E +L + +L++ + SLA + S + Q+ Q ++++ T TL+++ ++
Sbjct: 1036 YGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKE 1095
Query: 476 QQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVS-ELERKLTK-RDCVISELDTKV 533
QQLQ +++++K +E + EK +++ E+++TK + + S +
Sbjct: 1096 QQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESI 1155
Query: 534 SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQ 591
++ + Q +Q+ +LQ S K ++Q +++ ++ + + E L+ + I+
Sbjct: 1156 KEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIE 1213
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/439 (20%), Positives = 177/439 (40%), Gaps = 59/439 (13%)
Query: 241 LSELEIQVQKKDEEILLLQEERE-----ALKMQLKC-LLKGKGQETSMSPG--------- 285
LSE+E + Q E LQ++RE L++Q + L K ET G
Sbjct: 381 LSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQ 440
Query: 286 ----------RREQLSDASLKLGRL-SLLKAFSRHEEELQHWW----QMQEESAAPERGK 330
+ +Q++D LKL RL LK + ELQH Q +E A ++
Sbjct: 441 RQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQST 500
Query: 331 EPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEE-------GDRDED 383
L + D G +D + + E S E+E E E
Sbjct: 501 TAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGET 560
Query: 384 SEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVI 443
+ +L E+ + + + L E+L Q E ++Q + ++ + A +
Sbjct: 561 AVLNQLQEKNHTLQEQVTQLT----EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV 616
Query: 444 ASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQ--EMMGLI 501
SL ET + ++N++ ++++ + Q++A T+ + K Q ++ +
Sbjct: 617 LSL-------ETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHL 669
Query: 502 EKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKK 561
+ L+ + EL + T+ D V ++L K QE ++HL+ +K+ L+ K
Sbjct: 670 DTAQNALQDKQQELNKITTQLDQVTAKLQDK----QEHCSQLESHLKEYKEKYLSLEQKT 725
Query: 562 EMIQ-QAEQHTRVALESSQSRLERLRN----KIIQATFSISGTKSLANEISDNDILEALQ 616
E ++ Q ++ +LE S+ + L++ + + + T+ + +I+ + +
Sbjct: 726 EELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTR 785
Query: 617 RIISERSDYYNQLKQKGVK 635
+ ++S+ +KQK K
Sbjct: 786 LDLQKKSEALESIKQKLTK 804
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/298 (22%), Positives = 120/298 (40%), Gaps = 47/298 (15%)
Query: 367 EEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQ 426
EE EE + + +++L ++ R AS E+ + +L E + +
Sbjct: 322 EEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS---ETSLHRIHVELSEKGEATQKLK 378
Query: 427 FNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFS 486
L T+Y LQQQ + +E ++ +E L +L E +QL +
Sbjct: 379 EELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLK 438
Query: 487 NLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNH 546
R+ + L++K+ QQV++L+ KL++ + + E T ++LQ Q LD+
Sbjct: 439 EQRQLSSEK----LMDKE-----QQVADLQLKLSRLEEQLKEKVTNSTELQHQ--LDKTK 487
Query: 547 LQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEI 606
Q +Q Q +Q T L +Q+ LE++ +I I ++L +
Sbjct: 488 QQHQEQ------------QALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKS 535
Query: 607 SDNDILEALQRIISERSDYY-------------NQLKQKGVKVPPLQQSEAFLTSKSK 651
+N + + ER D Y NQL++K LQ+ LT K K
Sbjct: 536 KEN-----ISLLEKEREDLYAKIQAGEGETAVLNQLQEKN---HTLQEQVTQLTEKLK 585
Score = 48.9 bits (115), Expect = 1e-05
Identities = 79/403 (19%), Positives = 185/403 (45%), Gaps = 70/403 (17%)
Query: 241 LSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLG-- 298
++EL+ ++K ++I EAL+ +LK + Q+T + ++QL+ A+ +L
Sbjct: 961 INELKQSSEQKKKQI-------EALQGELKIAVL---QKTELENKLQQQLTQAAQELAAE 1010
Query: 299 --RLSLLKAFSRHEEELQHWWQMQEESAAPER---GKEPDLGGGEEDEGLEGEPDGVEDT 353
++S+L+ + +E+ + + Q+Q + E DL EE L E D + +
Sbjct: 1011 KEKISVLQ--NNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQE-DLISNR 1067
Query: 354 GAWGGVSQM--------GSVHEEGSEEEEE--------EEGDRDEDSEERELPEE----- 392
G +++ ++ ++ +++E++ ++ +++ +E+EL E
Sbjct: 1068 NQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLA 1127
Query: 393 --EEIPRRRASSLAESFEE---------ELLAQLEEYEQVILDFQFNLEATRTRYSLATG 441
EEI R+ + + EE + + L++ +Q+++ + L+ A
Sbjct: 1128 EIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGK------ADS 1181
Query: 442 VIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQA-MTDKFSNLREDKKHQ----- 495
+ A+++Q+ Q+ ++ E E L+KE E+ +L + + +K +++ ++++
Sbjct: 1182 LKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTM 1241
Query: 496 ------EMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQR 549
E +G ++K+ Q +++VSELE++ I+ L+ V Q++ +
Sbjct: 1242 QITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLK 1301
Query: 550 WKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQA 592
+ E LQ+K +Q+ +T A++ + L+ K QA
Sbjct: 1302 GEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQA 1344
Score = 45.8 bits (107), Expect = 1e-04
Identities = 80/418 (19%), Positives = 174/418 (41%), Gaps = 34/418 (8%)
Query: 245 EIQVQKKDEEILLLQEEREALKMQLK---CLLKGKGQETSMSPGRREQ-------LSDAS 294
E + K +++ LL++E + L+ LK + +E G ++Q ++D+S
Sbjct: 75 ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSS 134
Query: 295 LKLGRLSL-LKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDT 353
+L L L+ ++ + E+ AA + D+ ++E E + T
Sbjct: 135 AELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVT 194
Query: 354 GAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLA 413
+++ +V ++ E + G D ++EL + + + E E+L
Sbjct: 195 RLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLE-RERESEKLKD 253
Query: 414 QLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRE 473
+ ++ + + + R+ + +A Q++ ++ + ++ +N+TL + L +
Sbjct: 254 ECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLK 313
Query: 474 RRQQLQAMTDKFSNLREDKKH-QEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTK 532
+ Q + +K + KK+ Q + + D Q L+ ++S E L + +SE
Sbjct: 314 KEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEA 373
Query: 533 VSQLQE---QVELDQNHLQ-RWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNK 588
+L+E +VE HL+ +KQLQ+ + K EQH QS + +L +K
Sbjct: 374 TQKLKEELSEVETKYQHLKAEFKQLQQQREEK-------EQHGL----QLQSEINQLHSK 422
Query: 589 IIQATFSIS---GTKSLANEISDNDILEALQRIIS---ERSDYYNQLKQKGVKVPPLQ 640
+++ + G ++S +++ Q++ + S QLK+K LQ
Sbjct: 423 LLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQ 480
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 62.0 bits (149), Expect = 2e-09
Identities = 79/366 (21%), Positives = 170/366 (46%), Gaps = 28/366 (7%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREALKMQL--KCLLKGKGQETSMSPGRREQLSDA 293
E + LS + Q +K D I L +ER+AL ++L + + +E + + QL ++
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 223
Query: 294 SLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDT 353
+L++ + + E Q Q ++ A GKE + L+ + VE+
Sbjct: 224 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK----LQAQ---VEEN 276
Query: 354 GAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERE--LPEEEEIPRRRASSLAESFE--- 408
W ++Q EE +EE+ +R+E +E+E + E+EE RR+ + E E
Sbjct: 277 ELWNRLNQQ---QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333
Query: 409 --EELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENET 466
EE++ + EE + + + E R + +++Q QE + + E +
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEEKI 392
Query: 467 LQKE--LRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQ--VSELERKLTKR 522
++E +RE+ + +Q +K +E+K ++ + E++ ++ RQ+ + E E+K+ ++
Sbjct: 393 REQEEKIREQEEMMQEQEEKMGE-QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 523 DCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRL 582
+ I E + +QEQ E + + + +Q ++E +++ E+ R + + +
Sbjct: 452 EEKIREQE---EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 583 ERLRNK 588
E++R +
Sbjct: 509 EKIREQ 514
Score = 59.7 bits (143), Expect = 8e-09
Identities = 63/360 (17%), Positives = 169/360 (46%), Gaps = 41/360 (11%)
Query: 187 LLPFSKSICEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEI 246
LLP + E D+L K + Q++S + V + + ++ + E E
Sbjct: 245 LLPQQQLQAEADHLGK--ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302
Query: 247 QVQKKDEEILLLQEEREALKMQLKCLLKGKGQ---ETSMSPGRREQLSDASLKLGRLSLL 303
++Q+++E+I +E+ E ++ Q + + + + + + M + E++ + K+ +
Sbjct: 303 KIQEQEEKI---REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 359
Query: 304 KAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMG 363
R +EE + Q +E+ E+ +E + ++E + + + + +
Sbjct: 360 ----REQEEKR---QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE----------- 401
Query: 364 SVHEEGSEEEEEEEGDRDED--SEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQV 421
EE +E+EE+ G+++E +E E+ E+EE RR+ + E ++ + E E+
Sbjct: 402 --QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK-----IREQEEK 454
Query: 422 ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAM 481
I + + ++ + G + + ++ QE ++R+ + +K++RE+ ++++
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514
Query: 482 TDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE 541
+ +E+K ++ + E++ +++ E E K+ +++ + E + ++ Q +E+++
Sbjct: 515 EEMMQE-QEEKMWEQEEKMCEQE-----EKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 58.2 bits (139), Expect = 2e-08
Identities = 80/407 (19%), Positives = 189/407 (46%), Gaps = 46/407 (11%)
Query: 215 SSVASQSCLRKRMPWYLSVIHEKDHCLS-----------ELEIQVQKKDEEILLLQEERE 263
S+VA+Q +K+ Y+ + ++ LS EL+ + K E++ L++ E+
Sbjct: 170 SAVATQ---KKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 226
Query: 264 ALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGR-LSLLKAFSRHEEELQHWW----Q 318
+++ +K L + + + P ++QL + LG+ L + A + + E W Q
Sbjct: 227 EIQLNVKELKRKLERAKLLLP--QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 284
Query: 319 MQEESA--APERGKEPDLGGGEEDEGLEGEPDGV--EDTGAWGGVSQMGSVHEEGSEEEE 374
QEE E+ +E + E++E + + + + ++ W +M EE E+E
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR-QEEMMWEKE 343
Query: 375 EEEGDRDEDSEERELPEEEEIPRRRASSLAESFE-EELLAQLEEYEQVILDFQFNLEATR 433
E+ + +E E+E E+E R+ + E + +E A++ E+ I + + +
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 434 TRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKK 493
+ ++++ QE ++++ + ++++RE+ ++++ +K E +
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 494 HQE-MMGLIEKDNQLLRQQ--VSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQR- 549
QE MG E++ ++ Q+ + E E K+ +++ I E + K+ + +E++ + +Q
Sbjct: 464 EQEEKMG--EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521
Query: 550 ----WKQ------LQEDLQSKKEMIQQAEQHTR---VALESSQSRLE 583
W+Q +E +Q ++E +++ E+ R V L + +++
Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 31.2 bits (69), Expect = 3.2
Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Query: 247 QVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAF 306
Q +K E+ ++QE+ E + Q + + + + + R Q + ++ +
Sbjct: 395 QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 307 SRHEEELQHWWQMQEESAAPERGK--EPDLGGGEEDEGLEGEPDGV-EDTGAWGGVSQMG 363
R +EE+ Q QEE + GK E + E++E + + + + E +
Sbjct: 455 IREQEEMM---QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 364 SVHEEGSEEEEEEEGDRDEDS-EERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQ 420
EE +E+EE+ +++E E+ E +E+E RR E L Q E+ ++
Sbjct: 512 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 62.0 bits (149), Expect = 2e-09
Identities = 91/412 (22%), Positives = 184/412 (44%), Gaps = 42/412 (10%)
Query: 239 HCLSELE---IQVQKKDEEILLLQEEREALKMQLKCLL----KGKGQETSMSPGRR--EQ 289
HC ELE I+ Q +++E+ L EE ALK ++ L K E+++ R+ +
Sbjct: 274 HC-EELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQD 332
Query: 290 LSDASLKLGRLSLLKAFSRH-----EEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLE 344
L+D ++ L H EEEL+ + + +R + DL E
Sbjct: 333 LNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQ-DLHVKLSSESKR 391
Query: 345 GEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRD---EDSEERELPEEEEIPRRRAS 401
+ E + ++ HE +E+E RD E +EE + ++ +
Sbjct: 392 ADTLAFE-------MKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTD 444
Query: 402 SLAESFEEELLAQLE--EYEQVILDFQFNLEATRTRYSLATGV-IASLQQQVDFQETQLR 458
+ A E L A++ EY +V + Q + R + + I LQ+Q++ + ++
Sbjct: 445 ASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMN 504
Query: 459 KINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERK 518
++ TE ++ +RE +QQ++ + K + K E +++ + ++++E+ +
Sbjct: 505 ELETEQRLSKERIRELQQQIEDL-QKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEE 563
Query: 519 LTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESS 578
L K+ +I +L ++Q ++Q+ +L+ LQ K E ++ E+ ++ LE +
Sbjct: 564 LQKKQELIEDLQPDINQ----------NVQKINELEAALQKKDEDMKAMEERYKMYLEKA 613
Query: 579 QSRLERLRNKIIQATFSIS-GTKSLANEISDNDILEALQRIISERSDYYNQL 629
++ ++ L K+ A+ I K LA + +ILE+ ++ R DY +L
Sbjct: 614 RNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFR-DYEEKL 664
Score = 47.0 bits (110), Expect = 6e-05
Identities = 66/298 (22%), Positives = 128/298 (42%), Gaps = 39/298 (13%)
Query: 385 EERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQ------FNLEATRTRYSL 438
E+ L E E+ + L SF++ ++Y L + F LEA + Y +
Sbjct: 214 EKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRV 273
Query: 439 ATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLRED-----KK 493
+ +Q ++FQ + ET + L++ L+A +DK + L +K
Sbjct: 274 HCEELE--KQLIEFQHRNDELTSLAEET--RALKDEIDVLRATSDKANKLESTVEIYRQK 329
Query: 494 HQEMMGL------IEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQE-QVELDQNH 546
Q++ L +++ N + LE +L K + ++L+T Q+Q+ V+L
Sbjct: 330 LQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSES 389
Query: 547 LQ------RWKQLQED----LQSKKEMIQQAE--QHTRVALESSQSRLERLRNKIIQATF 594
+ K+L+E L+ K+ +I+Q + + T L SQ + + L AT
Sbjct: 390 KRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATK 449
Query: 595 SISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKSKK 652
S ++LA EI + E R+ + + +L+Q+G + +++ + L K +K
Sbjct: 450 SY---ENLAAEIMPVEYREVFIRL--QHENKMLRLQQEGSENERIEELQEQLEQKHRK 502
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 62.0 bits (149), Expect = 2e-09
Identities = 83/314 (26%), Positives = 135/314 (42%), Gaps = 57/314 (18%)
Query: 304 KAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMG 363
+AF + + Q + +E+ A E +E D G EE+EG E E ED+G S+
Sbjct: 566 EAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDED---EDSG-----SEES 617
Query: 364 SVHEEGSEEEEEEEGDRD------EDSEERELPEEEEIPRRRASSLAESFEEELLAQLEE 417
V + EE+E D E +++L +E E +RR +L +EE+L+
Sbjct: 618 LVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLIL---- 673
Query: 418 YEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQ 477
+ I D Q LE R V+ +L + E + KI + E +E+ Q+
Sbjct: 674 LQNKIRDTQ--LERDR--------VLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQK 723
Query: 478 LQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQ 537
LQA +K++ L + S ER+L K ++E+ L
Sbjct: 724 LQA--------------------AQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALM 763
Query: 538 EQV--ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLER-LRNKIIQATF 594
+Q+ E + L K+ +E Q KKE Q+ ++ ALES + + E LR K T
Sbjct: 764 KQMREEQQRRRLVETKRNREIAQLKKE--QRRQEFQIRALESQKRQQEMVLRRK----TQ 817
Query: 595 SISGTKSLANEISD 608
+S + LA +S+
Sbjct: 818 EVSALRRLAKPMSE 831
Score = 40.4 bits (93), Expect = 0.005
Identities = 62/249 (24%), Positives = 104/249 (41%), Gaps = 39/249 (15%)
Query: 355 AWGG--VSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELL 412
A+GG S M E +++ E + ++ +R E+E ++RA E+ EE
Sbjct: 525 AFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDE 584
Query: 413 AQLEEYEQVILDFQFNLEATRTRYSLATGVIASL--------QQQVDFQETQLRKINTEN 464
+ EE E+ + E R +G SL +++V+FQ L + E
Sbjct: 585 NEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQ-ADLADLTCEI 643
Query: 465 ETLQK---ELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTK 521
E QK EL +++LQ + KHQ LI N++ Q+ +
Sbjct: 644 EIKQKLIDELENSQRRLQTL-----------KHQYEEKLILLQNKIRDTQL--------E 684
Query: 522 RDCVISELDTKVSQLQEQV-ELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQS 580
RD V+ L T +E+ ++ ++ +R +++ DLQ QA Q L +QS
Sbjct: 685 RDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQK-----LQAAQKEHARLLKNQS 739
Query: 581 RLERLRNKI 589
R ER K+
Sbjct: 740 RYERELKKL 748
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 61.2 bits (147), Expect = 3e-09
Identities = 82/388 (21%), Positives = 169/388 (43%), Gaps = 40/388 (10%)
Query: 247 QVQKKDEEILLLQEEREALKM---QLKCLLKGKGQETSMSPGRREQLSDA--SLKLGRLS 301
Q+ +++EEI L+ ER ++ L+CL+ + M+ +R+ S A S ++ L
Sbjct: 103 QLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLK 162
Query: 302 LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQ 361
LK+ H + L E+ +E E LE E+ GA +
Sbjct: 163 ALKSLFEHHKALD------------EKVRERLRVALERCSLLE------EELGATH--KE 202
Query: 362 MGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQV 421
+ + E+ ++++ +G D + E+ P +R+S + S EE+L A++ E +++
Sbjct: 203 LMILKEQNNQKKTLTDGVLDINHEQENTPSTSG---KRSSDGSLSHEEDL-AKVIELQEI 258
Query: 422 ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAM 481
I + R + + + L++ +D L K N LQ+++RE Q + M
Sbjct: 259 ISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDM 318
Query: 482 TDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE 541
++ + L +K++ +++ + +LE ++ +D + + + K QLQE++E
Sbjct: 319 EERITTL--EKRYL----AAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLE 372
Query: 542 LDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQ-----ATFSI 596
L + LQ+ + E L + + Q A E + ERLR Q
Sbjct: 373 LAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQR 432
Query: 597 SGTKSLANEISDNDILEALQRIISERSD 624
+ + NE + + + + +++SE ++
Sbjct: 433 ARQREKMNEEHNKRLSDTVDKLLSESNE 460
Score = 34.7 bits (78), Expect = 0.29
Identities = 71/315 (22%), Positives = 128/315 (40%), Gaps = 50/315 (15%)
Query: 231 LSVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQL 290
L + HE+++ S K+ + L EE A ++L+ ++ + +E S R L
Sbjct: 221 LDINHEQENTPSTSG----KRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASL 276
Query: 291 S------DASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLE 344
S + L R L+K+ +LQ ++E A E +E + +
Sbjct: 277 SSHVTELEEDLDTARKDLIKS-EEMNTKLQR--DVREAMAQKEDMEERITTLEKRYLAAQ 333
Query: 345 GEPDGVEDTG--AWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEER---------ELPEEE 393
E V D ++ S+H + +E++ + +R E +E++ LPE E
Sbjct: 334 REATSVHDLNDKLENEIANKDSMHRQ-TEDKNRQLQERLELAEQKLQQTLRKAETLPEVE 392
Query: 394 EIPRRRASSLAESFEE---------ELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIA 444
+R ++L+++ E ++ AQLEE Q L+ R R +
Sbjct: 393 AELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQ-------ELQRARQREKMNEEHNK 445
Query: 445 SLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKD 504
L VD + ++ NE LQ L+ER + A+ DK S LRE + ++ + + D
Sbjct: 446 RLSDTVD------KLLSESNERLQLHLKER---MAALEDKNSLLREVESAKKQLEETQHD 496
Query: 505 NQLLRQQVSELERKL 519
L + L +L
Sbjct: 497 KDQLVLNIEALRAEL 511
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 61.2 bits (147), Expect = 3e-09
Identities = 82/388 (21%), Positives = 169/388 (43%), Gaps = 40/388 (10%)
Query: 247 QVQKKDEEILLLQEEREALKM---QLKCLLKGKGQETSMSPGRREQLSDA--SLKLGRLS 301
Q+ +++EEI L+ ER ++ L+CL+ + M+ +R+ S A S ++ L
Sbjct: 103 QLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLK 162
Query: 302 LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQ 361
LK+ H + L E+ +E E LE E+ GA +
Sbjct: 163 ALKSLFEHHKALD------------EKVRERLRVALERCSLLE------EELGATH--KE 202
Query: 362 MGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQV 421
+ + E+ ++++ +G D + E+ P +R+S + S EE+L A++ E +++
Sbjct: 203 LMILKEQNNQKKTLTDGVLDINHEQENTPSTSG---KRSSDGSLSHEEDL-AKVIELQEI 258
Query: 422 ILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAM 481
I + R + + + L++ +D L K N LQ+++RE Q + M
Sbjct: 259 ISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDM 318
Query: 482 TDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVE 541
++ + L +K++ +++ + +LE ++ +D + + + K QLQE++E
Sbjct: 319 EERITTL--EKRYL----AAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLE 372
Query: 542 LDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQ-----ATFSI 596
L + LQ+ + E L + + Q A E + ERLR Q
Sbjct: 373 LAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQR 432
Query: 597 SGTKSLANEISDNDILEALQRIISERSD 624
+ + NE + + + + +++SE ++
Sbjct: 433 ARQREKMNEEHNKRLSDTVDKLLSESNE 460
Score = 34.7 bits (78), Expect = 0.29
Identities = 71/315 (22%), Positives = 128/315 (40%), Gaps = 50/315 (15%)
Query: 231 LSVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQL 290
L + HE+++ S K+ + L EE A ++L+ ++ + +E S R L
Sbjct: 221 LDINHEQENTPSTSG----KRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASL 276
Query: 291 S------DASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLE 344
S + L R L+K+ +LQ ++E A E +E + +
Sbjct: 277 SSHVTELEEDLDTARKDLIKS-EEMNTKLQR--DVREAMAQKEDMEERITTLEKRYLAAQ 333
Query: 345 GEPDGVEDTG--AWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEER---------ELPEEE 393
E V D ++ S+H + +E++ + +R E +E++ LPE E
Sbjct: 334 REATSVHDLNDKLENEIANKDSMHRQ-TEDKNRQLQERLELAEQKLQQTLRKAETLPEVE 392
Query: 394 EIPRRRASSLAESFEE---------ELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIA 444
+R ++L+++ E ++ AQLEE Q L+ R R +
Sbjct: 393 AELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQ-------ELQRARQREKMNEEHNK 445
Query: 445 SLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKD 504
L VD + ++ NE LQ L+ER + A+ DK S LRE + ++ + + D
Sbjct: 446 RLSDTVD------KLLSESNERLQLHLKER---MAALEDKNSLLREVESAKKQLEETQHD 496
Query: 505 NQLLRQQVSELERKL 519
L + L +L
Sbjct: 497 KDQLVLNIEALRAEL 511
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 60.8 bits (146), Expect = 4e-09
Identities = 87/378 (23%), Positives = 161/378 (42%), Gaps = 64/378 (16%)
Query: 241 LSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRL 300
L+EL++ +Q+++ ++ LQ R AL+ QL+ K + +ET+
Sbjct: 876 LTELQLSLQERESQLTALQAARAALESQLR-QAKTELEETTAEAEEE------------- 921
Query: 301 SLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEG--------LEGEPDGVED 352
++A + H +E+Q + S E L ED L + D E
Sbjct: 922 --IQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLD--EA 977
Query: 353 TGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELL 412
+GA + Q+ S + E E E + E + E+ +ELL
Sbjct: 978 SGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELL 1037
Query: 413 A---QLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKI--------N 461
Q E + V+ D + E + + D + T+ R++
Sbjct: 1038 EKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHK 1097
Query: 462 TENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTK 521
E LQ+ L+E++ + ++++DK ++L +KKH ++E + + L+Q++ E ER+L +
Sbjct: 1098 AEILALQQALKEQKLKAESLSDKLNDL--EKKH----AMLEMNARSLQQKL-ETERELKQ 1150
Query: 522 RDCVISELDTKVSQLQEQVELDQNHLQRWKQ-LQE-------------DLQSKKEMIQQA 567
R L + ++LQ+Q++L +NH+ R Q LQE DL+ + E IQ
Sbjct: 1151 R------LLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVL 1204
Query: 568 EQHTRVALESSQSRLERL 585
H +V +E + S+ +L
Sbjct: 1205 YSHEKVKMEGTISQQTKL 1222
Score = 54.3 bits (129), Expect = 3e-07
Identities = 67/302 (22%), Positives = 126/302 (41%), Gaps = 32/302 (10%)
Query: 365 VHEEGSEEEEEEEGDRDEDSEERELP----EEEEIPRRRASSLAESFEEELLAQLEEYEQ 420
+ E+ + +E +E + EE L EE+ + RR S L ES E EE+++
Sbjct: 542 IREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKR 601
Query: 421 VILDFQFNLEATRTRYSLATGVIASL-----QQQVDFQETQLR-----KINTENETLQKE 470
+ Q L + + G A L +QQ+ QE Q + K +TE L +
Sbjct: 602 KATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQN 661
Query: 471 LRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELD 530
+R+ +++ + +K N RED L+E + ELE K + L+
Sbjct: 662 IRQAKERAERELEKLQN-REDSSEGIRKKLVEAE---------ELEEKHREAQVSAQHLE 711
Query: 531 TKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKII 590
+ Q ++ E L Q+++DL K+ + ++H A E + L + I
Sbjct: 712 VHLKQKEQHYEEKIKVLD--NQIKKDLADKETLENMMQRHEEEAHEKGKI-LSEQKAMIN 768
Query: 591 QATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGVKVPPLQQSEAFLTSKS 650
I + E+S+ + L A + ++R+ +K + + L+Q + +L +++
Sbjct: 769 AMDSKIRSLEQRIVELSEANKLAANSSLFTQRN-----MKAQEEMISELRQQKFYLETQA 823
Query: 651 KK 652
K
Sbjct: 824 GK 825
Score = 48.5 bits (114), Expect = 2e-05
Identities = 101/546 (18%), Positives = 216/546 (39%), Gaps = 57/546 (10%)
Query: 94 KSVQTISRYYRKTSEPKDAASLTGFMSKMELRRVFPTHPDCPQFSTRATSMSHCGSPTEA 153
K Q ++R +R+ SE + S K + D + T +S+
Sbjct: 467 KMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARM 526
Query: 154 DLSGEIDNSSETWRGTQDLFLARRGSDTNVDGYLLPFSK-----SICEFDYLRKRRKSQT 208
++S E D + + ++ +R+ + Y + + E D + RR+S
Sbjct: 527 EVSQEDDKALQLLHDIREQ--SRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDL 584
Query: 209 L-SPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQEER-EALK 266
S + S +A++ RK ++ KD + E+ K E+I Q+ + + L+
Sbjct: 585 YESELRESRLAAEEFKRKATECQHKLLKAKDQ--GKPEVGEYAKLEKINAEQQLKIQELQ 642
Query: 267 MQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAP 326
+L+ +K + T + R+ A +L +L +R + ++ E
Sbjct: 643 EKLEKAVKASTEATELLQNIRQAKERAERELEKLQ-----NREDSSEGIRKKLVEAEELE 697
Query: 327 ERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEG----DRDE 382
E+ +E + + L+ + E+ + + + ++ ++E E +E
Sbjct: 698 EKHREAQVSAQHLEVHLKQKEQHYEEK-----IKVLDNQIKKDLADKETLENMMQRHEEE 752
Query: 383 DSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGV 442
E+ ++ E++ S S E+ ++ +L E ++ + T+ +
Sbjct: 753 AHEKGKILSEQKAMINAMDSKIRSLEQRIV-ELSEANKLAANSSL---FTQRNMKAQEEM 808
Query: 443 IASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIE 502
I+ L+QQ + ETQ K+ +N L+++L + Q +DK L + + +E+ E
Sbjct: 809 ISELRQQKFYLETQAGKLEAQNRKLEEQLEKISH--QDHSDKNRLLELETRLREVSLEHE 866
Query: 503 KDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKE 562
+ L++Q++EL+ L +R+ ++ L + L+ Q+ Q +L+E +E
Sbjct: 867 EQKLELKRQLTELQLSLQERESQLTALQAARAALESQLR------QAKTELEETTAEAEE 920
Query: 563 MIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISER 622
IQ H + Q + + LRN T D+ E L ++ +
Sbjct: 921 EIQALTAHR----DEIQRKFDALRNSCTVIT----------------DLEEQLNQLTEDN 960
Query: 623 SDYYNQ 628
++ NQ
Sbjct: 961 AELNNQ 966
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 60.5 bits (145), Expect = 5e-09
Identities = 88/425 (20%), Positives = 179/425 (42%), Gaps = 60/425 (14%)
Query: 241 LSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRL 300
L+EL + +++ EE LL++E +L QL+ L Q + EQ
Sbjct: 487 LAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQK---------- 536
Query: 301 SLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVS 360
K + ++ L M E A P + P GE++E L +++ AWG
Sbjct: 537 ---KQLIQDKDHLSQQVGMLERLAGPPGPELPV--AGEKNEALVPVNSSLQE--AWG--- 586
Query: 361 QMGSVHEEGSEEEEEEEGDRD---EDSEERELPEEEEIPRRRASSLAESFEEELLAQLEE 417
+ EEE+ G ++ +D++ +E +EEE+ R+A+ E + ++ + +
Sbjct: 587 ----------KPEEEQRGLQEAQLDDTKVQEGSQEEEL--RQANRELEKELQNVVGRNQL 634
Query: 418 YEQVILDFQFNLEATRTRYSLATGVIASLQQQV-------DFQETQLRKINTENETLQKE 470
E + Q + +A + R S G +ASL+ + D E L + E ++ +
Sbjct: 635 LEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQ 694
Query: 471 LRERRQQLQAMTDKFSNLRED---------KKHQEMMGL---IEKDNQLLRQQVSELERK 518
+ E+ LQ+ + LRE+ +H+E+ L ++ QL+ +E ++
Sbjct: 695 MAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQ 754
Query: 519 LT--KRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALE 576
D EL +++ Q Q+E+ Q +QR + DLQ+K + + L
Sbjct: 755 GVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLS 814
Query: 577 SSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGVKV 636
+++ L + + Q + N ++L+ +R + + + ++ +Q+ ++
Sbjct: 815 MAEAVLREHKTLVQQ----LKEQNEALNRAHVQELLQCSEREGALQEERADEAQQREEEL 870
Query: 637 PPLQQ 641
LQ+
Sbjct: 871 RALQE 875
Score = 47.0 bits (110), Expect = 6e-05
Identities = 92/488 (18%), Positives = 187/488 (38%), Gaps = 78/488 (15%)
Query: 205 KSQTLSPVTSSSVASQSCLRK---RMPWYLSVIHEKDHCLSELE-IQVQKKDEEILLLQE 260
+S ++S + SS + +Q + P + D EL+ ++V++K + Q
Sbjct: 197 RSSSMSSLVSSYLQTQEMVSNFDLNSPLNNEALEGFDEMRLELDQLEVREKQLRERMQQL 256
Query: 261 EREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQ 320
+RE +++ +G+ +T GR + RL+ L A ELQ W++
Sbjct: 257 DRENQELRAAVSQQGEQLQTERERGRTAAEDNV-----RLTCLVA------ELQKQWEVT 305
Query: 321 EESAAPERGKEP-----DLGGGEEDEG------------------LEGEPDGVEDTG--- 354
+ + + + +LG E++E LE D ++
Sbjct: 306 QATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHL 365
Query: 355 ----AWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEE 410
W ++Q + +E D E +EL E+ + R + + EE
Sbjct: 366 ASFPGWLAMAQQ-KADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKV----EEV 420
Query: 411 LLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKE 470
Q + EQ++ + Q +A R +A LQ+++ + E + L +
Sbjct: 421 NRQQSAQLEQLVKELQLKEDA-RASLERLVKEMAPLQEELSGK-------GQEADQLWRR 472
Query: 471 LRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELD 530
L+E + ++ + LR +KK Q+ ++ +LL Q+V L R+L + ++++
Sbjct: 473 LQELLAHTSSWEEELAELRREKKQQQ------EEKELLEQEVRSLTRQLQFLETQLAQVS 526
Query: 531 TKVSQLQEQVE---LDQNHLQRWKQLQEDLQ-----------SKKEMIQQAEQHTRVALE 576
VS L+EQ + D++HL + + E L K E + + A
Sbjct: 527 QHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQEAWG 586
Query: 577 SSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGVKV 636
+ L+ + T G++ ++ ++ + LQ ++ +L+
Sbjct: 587 KPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQADY 646
Query: 637 PPLQQSEA 644
LQQ E+
Sbjct: 647 QALQQRES 654
Score = 38.9 bits (89), Expect = 0.015
Identities = 68/322 (21%), Positives = 127/322 (39%), Gaps = 46/322 (14%)
Query: 247 QVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGR-REQLSDASLKLGRLSLLKA 305
+ Q+++EE+ LQEE Q KC +E + +EQL A+ L +
Sbjct: 862 EAQQREEELRALQEELS----QAKC----SSEEAQLEHAELQEQLHRANTDTAELGIQVC 913
Query: 306 FSRHEEELQHWWQMQEESA-APERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGS 364
E+E +++E A A + ++ E EGLE Q+
Sbjct: 914 ALTVEKE-----RVEEALACAVQELQDAKEAASREREGLE---------------RQVAG 953
Query: 365 VHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILD 424
+ +E +E+ + + L + +RA SL E+ +EL + I+D
Sbjct: 954 LQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMD 1013
Query: 425 FQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDK 484
+Q +R A SL+ Q++ Q QL+ E L+ + ++L ++
Sbjct: 1014 YQ-------SRLKNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNH 1066
Query: 485 FSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQ 544
+ Q M +K+ LR+ + +++L K I E K+ QE ++
Sbjct: 1067 LAEC------QAAMLRKDKEGAALREDLERTQKELEKATTKIQEYYNKL--CQEVTNRER 1118
Query: 545 NHLQRWKQLQEDLQSKKEMIQQ 566
N + L +DL K+ +++
Sbjct: 1119 NDQKMLADL-DDLNRTKKYLEE 1139
Score = 33.9 bits (76), Expect = 0.49
Identities = 52/252 (20%), Positives = 99/252 (39%), Gaps = 56/252 (22%)
Query: 383 DSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEAT-------RTR 435
D+E REL + +L+++ E +++ + ++D Q + A +++
Sbjct: 761 DNEARELAAQ--------LALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQ 812
Query: 436 YSLATGVIA---SLQQQVDFQETQLRKINTEN------------ETLQKELRERRQQLQA 480
S+A V+ +L QQ+ Q L + + + E E ++R ++L+A
Sbjct: 813 LSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQREEELRA 872
Query: 481 MTDKFSNLR--------EDKKHQEMMGLIEKDNQLLRQQVSEL----ERKLTKRDCVISE 528
+ ++ S + E + QE + D L QV L ER C + E
Sbjct: 873 LQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQE 932
Query: 529 L--------------DTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVA 574
L + +V+ LQ++ E Q L+ K L + + QAEQ +
Sbjct: 933 LQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSL 992
Query: 575 LESSQSRLERLR 586
E++ L L+
Sbjct: 993 QEAAHQELNTLK 1004
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 60.5 bits (145), Expect = 5e-09
Identities = 70/351 (19%), Positives = 150/351 (42%), Gaps = 24/351 (6%)
Query: 244 LEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRRE-----QLSDASLKLG 298
LE ++++ + L +E++ L L+ +GK +E + G+ E +L D ++
Sbjct: 798 LEARLEEAQRGLARLGQEQQTLNRALE--EEGKQREV-LRRGKAELEEQKRLLDRTVDRL 854
Query: 299 RLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGG 358
L K ++ LQ E+ R + D +D E E GG
Sbjct: 855 NKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTS-------GG 907
Query: 359 VSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEY 418
+S++ + + + + +RD ++EL + + + + +++ QL+
Sbjct: 908 LSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGL 967
Query: 419 EQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQL 478
E+ + + L+ + L T + + QVD T+L + + + L+ + +Q
Sbjct: 968 EEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQN 1027
Query: 479 QAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQE 538
+ + + ++ +K + +E NQLL++++ ER+ T +L+ KV +L
Sbjct: 1028 KDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSI 1087
Query: 539 QVELDQNHLQRWK-QLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNK 588
Q+E ++ H+ K QL +++ K + +AE+ RL+ LR K
Sbjct: 1088 QIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEI--------ERLDGLRKK 1130
Score = 54.7 bits (130), Expect = 3e-07
Identities = 61/264 (23%), Positives = 116/264 (43%), Gaps = 30/264 (11%)
Query: 364 SVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEE---ELLAQLEEYEQ 420
++ EEG + E G + + ++R L + + + E ++ +L AQLE+Y++
Sbjct: 822 ALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKE 881
Query: 421 VILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQA 480
A +A Q+Q ++ K + LQ E++ RQ LQA
Sbjct: 882 K-----------------ARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQA 924
Query: 481 MTDKFSNLREDKK--HQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQE 538
+ R DK+ Q + GL ++ R Q + R+L + +S L+T++ + +
Sbjct: 925 SQAERDTARLDKELLAQRLQGLEQEAENKKRSQ-DDRARQLKGLEEKVSRLETELDEEKN 983
Query: 539 QVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISG 598
VEL + + R + + L++ E++Q E+ R LE + LER + S G
Sbjct: 984 TVELLTDRVNRGRDQVDQLRT--ELMQ--ERSARQDLECDKISLERQNKDLKTRLASSEG 1039
Query: 599 TKSLANEISDNDILEALQRIISER 622
+ + +S LE+ +++ ER
Sbjct: 1040 FQKPSASLSQ---LESQNQLLQER 1060
Score = 48.9 bits (115), Expect = 1e-05
Identities = 90/409 (22%), Positives = 174/409 (42%), Gaps = 56/409 (13%)
Query: 244 LEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLL 303
LE Q+++K EE LQE E K G+ Q+++ ++L D L R L
Sbjct: 392 LERQLEEKTEECSRLQELLERRK--------GEAQQSNKELQNMKRLLDQGEDL-RHGLE 442
Query: 304 KAFSRHEEELQHWWQMQEESAAPERGKE---PDLGGGEE--DEGLEGEPDGVEDTGAWGG 358
+ +L+H PE KE DL E +E LEG+ E
Sbjct: 443 TQVMELQNKLKH-------VQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRER 495
Query: 359 --VSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLE 416
+ G++ EE + ++E E R + + E RR+ A L A+ +
Sbjct: 496 ELTALKGALKEEVASRDQEVEHVRQQYQRDTE-------QLRRSMQDATQDHAVLEAERQ 548
Query: 417 EYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQ 476
+ ++ Q LE T + ++ + + +L ++ E E +++EL E+ +
Sbjct: 549 KMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIE 608
Query: 477 QLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCV----ISELDTK 532
LQ ++ D + E +++K+ ++++ EL+ + ++ EL+ +
Sbjct: 609 VLQRELEQARASAGDTRQVE---VLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQ 665
Query: 533 VSQLQEQV----ELDQNHLQRWKQLQEDLQ-----SKKEMIQQAEQ----HTRVALES-- 577
++ L+ + EL++ +LQ K LQ+ Q SK +M+ +AE R A+E+
Sbjct: 666 LAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTL 725
Query: 578 --SQSRLERLRNKIIQATFSISGTKSLAN--EISDNDILEALQRIISER 622
+Q + R +I+ + T+ L + E + + + LQR+ +E+
Sbjct: 726 RETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEK 774
Score = 41.2 bits (95), Expect = 0.003
Identities = 50/258 (19%), Positives = 115/258 (44%), Gaps = 29/258 (11%)
Query: 395 IPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQE 454
I R +S S ++ LE+ + +++ + +A + L T + LQ+++D +
Sbjct: 321 ILREGSSESETSVRRKVSLVLEKMQPLVMVSSGSTKAVAGQGEL-TRKVEELQRKLDEEV 379
Query: 455 TQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSE 514
+ +K+ L+++L E+ ++ + QE++ + + Q +++
Sbjct: 380 KKRQKLEPSQVGLERQLEEKTEECSRL-------------QELLERRKGEAQQSNKELQN 426
Query: 515 LERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVA 574
++R L + + + L+T+V +LQ +++ Q + L +DL +E++++
Sbjct: 427 MKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEE-------V 479
Query: 575 LESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQKGV 634
LE Q E+LR + + T ++ G +L E++ D Q + R Y +Q
Sbjct: 480 LEGKQRVEEQLRLRERELT-ALKG--ALKEEVASRD-----QEVEHVRQQYQRDTEQLRR 531
Query: 635 KVPPLQQSEAFLTSKSKK 652
+ Q A L ++ +K
Sbjct: 532 SMQDATQDHAVLEAERQK 549
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/122 (18%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Query: 370 SEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNL 429
SE ++ + + +L +E R ++ +S +L +++E I D + ++
Sbjct: 1037 SEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHV 1096
Query: 430 EATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLR 489
+ + SL + +L++QVD E ++ +++ + Q+E+ E+ + + + + +L
Sbjct: 1097 NDQKDQLSLR---VKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLE 1153
Query: 490 ED 491
+D
Sbjct: 1154 KD 1155
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 60.5 bits (145), Expect = 5e-09
Identities = 90/450 (20%), Positives = 196/450 (43%), Gaps = 67/450 (14%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRRE-----------QLS 291
EL+++V ++E + L Q+E E+ +++L+ L K S P +RE Q+S
Sbjct: 484 ELKVRVAAQNERLDLCQQEIESSRVELRSLEK----IISQLPLKRELFGFKSYLSKYQMS 539
Query: 292 DASLKLGR-LSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGV 350
S K R + +A EL+ ++E A + +L + + L D
Sbjct: 540 SFSNKEDRCIGCCEANKLVISELRIKLAIKE---AEIQKLHANLTANQLSQSLITCNDSQ 596
Query: 351 EDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEE 410
E S++ S+ E + + + +D + + ++ E R+R + E +
Sbjct: 597 ES-------SKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTK 649
Query: 411 LL-----------------AQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQ 453
L+ +Q + ++ +L+ N + + + +L++Q++ +
Sbjct: 650 LIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEK 709
Query: 454 ETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQL------ 507
I +N L++EL E+ ++++++ + +H+++ EK ++
Sbjct: 710 IVAYSSIAAKNAELEQELMEKNEKIRSLETNINT-----EHEKICLAFEKAKKIHLEQHK 764
Query: 508 -LRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQ 566
+ +Q+ LE +L K+D E + +S LQ+ + Q+HL+ +L +SK EM ++
Sbjct: 765 EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLL--TESKGEMKKE 822
Query: 567 AEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYY 626
+ L+ L+N++ + T + S A EI +++ L ++ + +
Sbjct: 823 NMK--------KDEALKALQNQVSEETIKVRQLDS-ALEICKEELVLHLNQLEGNKEKFE 873
Query: 627 NQLKQKGVKVPPLQQSEAFLTSKSKKGTSK 656
QLK+K +V LQ+ E + + S + TS+
Sbjct: 874 KQLKKKSEEVYCLQK-ELKIKNHSLQETSE 902
Score = 60.1 bits (144), Expect = 6e-09
Identities = 83/375 (22%), Positives = 163/375 (43%), Gaps = 43/375 (11%)
Query: 243 ELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQ---LSDASLKLGR 299
+ E Q++KK EE+ LQ+E LK++ L + Q + ++Q L +++ G
Sbjct: 871 KFEKQLKKKSEEVYCLQKE---LKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGE 927
Query: 300 LS-----LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTG 354
L L K S+ E+ELQ + +E SA R E + L+ + +E TG
Sbjct: 928 LEDTQTKLEKQVSKLEQELQ---KQRESSAEKLRKMEEKCESAAHEADLKRQKV-IELTG 983
Query: 355 AWGGVS-QMGSVHEEGSEEEEE---------------EEGDRDEDSEERELPEEEEIPRR 398
V +M EE S+ E+E + D D + EL E++ +
Sbjct: 984 TARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTEL-EKKTNAVK 1042
Query: 399 RASSLAESFEEELLAQLEEYEQVILDFQF---NLEATRTRYSLATGVIASLQQQVDFQET 455
L S E EL L++ E + + Q L++T + V+ Q ++ + T
Sbjct: 1043 ELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYT 1102
Query: 456 QLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSEL 515
++ + E + E+ +++Q+L M + K + + + +R+ E+
Sbjct: 1103 TIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQ--VTHLDMTIREHRGEM 1160
Query: 516 ERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQ---HTR 572
E+K+ K + + + + ++ + +Q+E + LQ K E L+ K+ ++ Q EQ +
Sbjct: 1161 EQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAK---EQLREKEFIMLQNEQEISQLK 1217
Query: 573 VALESSQSRLERLRN 587
+E +Q R++ + +
Sbjct: 1218 KEIERTQQRMKEMES 1232
Score = 53.5 bits (127), Expect = 6e-07
Identities = 75/376 (19%), Positives = 169/376 (44%), Gaps = 33/376 (8%)
Query: 236 EKDHCLSELEIQVQKKDEEILLLQEEREAL-----KMQLKCLLKGKGQETSMSPGRREQL 290
E + ++LE QV K ++E LQ++RE+ KM+ KC + E + + +L
Sbjct: 927 ELEDTQTKLEKQVSKLEQE---LQKQRESSAEKLRKMEEKC--ESAAHEADLKRQKVIEL 981
Query: 291 SDAS--LKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPD 348
+ + +K+ + S+ E+E+ H + E A + D+ + LE + +
Sbjct: 982 TGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAM--HLSQLDMILDQTKTELEKKTN 1039
Query: 349 GVEDTGAWGGVSQMG---SVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAE 405
V++ ++ ++ + E E + + S R+L E ++ ++ SL E
Sbjct: 1040 AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEE 1099
Query: 406 SFE---------EELLAQLEEYEQVILDFQFNLEAT----RTRYSLATGVIASLQQQVDF 452
+ E ++E+ +Q +L+ L+ + R + T + ++++
Sbjct: 1100 KYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGE 1159
Query: 453 QETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGL-IEKDNQLLRQQ 511
E ++ K+ E + EL+E +Q++++ DK N +E + +E + L E++ L+++
Sbjct: 1160 MEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 1219
Query: 512 VSELERKLTKRDCVISELDTKV-SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQH 570
+ ++++ + + V+ E + + +Q +E ++L Q +Q+Q E Q Q
Sbjct: 1220 IERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQA 1279
Query: 571 TRVALESSQSRLERLR 586
R +E S LE ++
Sbjct: 1280 QR-EIERLSSELEDMK 1294
Score = 44.7 bits (104), Expect = 3e-04
Identities = 51/228 (22%), Positives = 102/228 (44%), Gaps = 18/228 (7%)
Query: 372 EEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEE------ELLAQLEE---YEQVI 422
E E D+ E +L + +++ + SL ES EE +LL Q ++ E+
Sbjct: 297 EAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQR 356
Query: 423 LDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRER----RQQL 478
+ +N E + +A ++V +E L + T E K L+ER + +L
Sbjct: 357 NEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSEL 416
Query: 479 QAMTDKFSNLREDKKH-QEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQ 537
+ + +K L+E+ + +E + ++ N + Q++E + + K + SEL+ K L+
Sbjct: 417 EILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLE---SELENKDEILR 473
Query: 538 EQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERL 585
++ L N + K + ++ QQ + +RV L S + + +L
Sbjct: 474 DKFSL-MNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQL 520
Score = 42.7 bits (99), Expect = 0.001
Identities = 42/237 (17%), Positives = 112/237 (47%), Gaps = 31/237 (13%)
Query: 373 EEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQ--LEEYEQVILDFQFNLE 430
E+ +E ++ + E +L ++++ + + +++ ++ + Q LE ++++ + + ++
Sbjct: 761 EQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMK 820
Query: 431 ATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLRE 490
+ A + +LQ QV + ++R++++ E ++EL QL+ +KF ++
Sbjct: 821 KENMKKDEA---LKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFE--KQ 875
Query: 491 DKKHQEMMGLIEKD--------------NQLLRQQVSELERKLTKRDCVISELDTKVSQL 536
KK E + ++K+ N +L+ + + ++ L + EL+ ++L
Sbjct: 876 LKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKL 935
Query: 537 QEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQAT 593
++QV +L+++LQ ++E + + ES+ + R K+I+ T
Sbjct: 936 EKQVS----------KLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELT 982
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.1 bits (144), Expect = 6e-09
Identities = 78/416 (18%), Positives = 183/416 (43%), Gaps = 36/416 (8%)
Query: 187 LLPFSKSICEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEI 246
LLP + E D+L K + Q++S + V + + ++ + E E
Sbjct: 318 LLPQQQLQAEADHLGK--ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 375
Query: 247 QVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAF 306
++Q+++E+I +E+ + +++ + ++ + E + + K+ R +
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE--EMM 433
Query: 307 SRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVH 366
EE+++ +++E+ E+ +E + EE++ E E ++ W ++
Sbjct: 434 WEKEEKIR---ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 367 EEGSEEEE-----EEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLE---EY 418
E+ E+EE EE+ E E E +E+E R+ + E +EE+ Q E E
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE--QEEIWRQKEKIHEQ 548
Query: 419 EQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQL 478
E+ I + + + I +++V QE ++R+ + ++++RE+ +
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMT 608
Query: 479 QAMTDKFSNLRE-----DKKHQEMMGLIEKDNQLLRQQ---VSELERKLTKRDCVISELD 530
Q +K E ++K QE + + + +R+Q + E E K+ +++ ++ E +
Sbjct: 609 QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 668
Query: 531 TKV-----------SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVAL 575
K+ ++QEQ E + ++ + + L+ ++E +Q+ ++H A+
Sbjct: 669 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/419 (20%), Positives = 185/419 (44%), Gaps = 53/419 (12%)
Query: 215 SSVASQSCLRKRMPWYLSVIHEKDHCLS-----------ELEIQVQKKDEEILLLQEERE 263
S+VA+Q +K+ Y+ + ++ LS EL+ + K E++ L++ E+
Sbjct: 243 SAVATQ---KKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 299
Query: 264 ALKMQLKCLLKGKGQETSMSPGRR---------EQLSDASLKL----------GRLSLLK 304
+++ +K L + + + P ++ ++L S KL RL+ +
Sbjct: 300 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 359
Query: 305 AFS--RHEEELQHWWQMQEESAAPERGKEPDLGGGEE----DEGLEGEPDGV---EDTGA 355
R EE++Q W + +E R +E + EE E + E + ++
Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 419
Query: 356 WGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFE-EELLAQ 414
W +M EE E+EE+ + +E E+E E+E R+ + E + +E A+
Sbjct: 420 WEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478
Query: 415 LEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRER 474
+ E+ I + + E R + + +Q +E + R+ E ++++RE+
Sbjct: 479 MWRQEEKIREQE---EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535
Query: 475 RQQLQAMTDKFSNLRED-KKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKV 533
+++ +K E +K +E M E+ +++ E E K+ +++ I E + K+
Sbjct: 536 -EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594
Query: 534 SQ----LQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNK 588
+ ++EQ E+ Q ++ + +E + ++E +Q+ E+ R E + + +++R +
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653
Score = 52.4 bits (124), Expect = 1e-06
Identities = 48/230 (20%), Positives = 107/230 (46%), Gaps = 14/230 (6%)
Query: 365 VHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEY----EQ 420
+HE+ E+EE+ +E E+E +E+E R EE++ Q E+ E+
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK 506
Query: 421 VILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQA 480
+ + E R +++Q + Q KI+ + E ++K+ + +Q +
Sbjct: 507 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR-QKEKIHEQEEKIRKQEEKMWRQEEK 565
Query: 481 MTDKFSNLRE-DKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQ-- 537
M D+ +RE ++K I + + +R+Q E K+ +++ + E + K+ + +
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQ----EEKIREQEEMTQEQEEKMGEQEEK 621
Query: 538 --EQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERL 585
EQ E Q ++ ++ +E ++ +++ I++ E+ R E Q + E++
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 60.1 bits (144), Expect = 6e-09
Identities = 63/284 (22%), Positives = 132/284 (46%), Gaps = 38/284 (13%)
Query: 387 RELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFN-----------LEATRTR 435
+ L ++ E RR A + ++ E++ +E E + L + + +A +T
Sbjct: 320 KSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTV 379
Query: 436 YSLATGVIASLQQQVDFQETQLRKI------NTENETLQ-KELRERRQQLQAMTDKFSNL 488
+ IASL++ + E +++ + NTE+ + K++ + + M K L
Sbjct: 380 IEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQL 439
Query: 489 RED--KKHQEMMGL------IEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQV 540
+++ KK E++ L + N +Q + L+ LT ++ + L T+V L+ ++
Sbjct: 440 KQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 499
Query: 541 ELDQNHL-QRWKQLQE----------DLQSKKEMIQQAEQHTRVALESSQSRLERLRNKI 589
E ++ L ++ KQLQ+ +++ K+M++ E+ V + ++ E+LR+K
Sbjct: 500 EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKD 559
Query: 590 IQATFSISGTKSLANEISDND-ILEALQRIISERSDYYNQLKQK 632
Q T KSL + S+ D L L+ +SE+ +LK++
Sbjct: 560 KQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQ 603
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/323 (17%), Positives = 128/323 (39%), Gaps = 75/323 (23%)
Query: 388 ELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQ 447
E+ +E + + +++ ++ + L +LEE E + L+ G I ++
Sbjct: 472 EVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMK 531
Query: 448 QQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNL------------------- 488
++ +E ++ + + E LQ++LR++ +QL + D+ +L
Sbjct: 532 DMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALS 591
Query: 489 --------------REDKKHQEMMGLIEKDNQLLRQQVSELERKLT-------------- 520
R+D++ E + K+N+ L+++V+ L+ +LT
Sbjct: 592 EKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS 651
Query: 521 -------KRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQ---- 569
KRD + L+ + Q +E+ + L++ +++D + E Q +Q
Sbjct: 652 SLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKE 711
Query: 570 --HTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYN 627
+ R +Q+ ++RL + K + NE +D D ++I S
Sbjct: 712 ASYYRDECGKAQAEVDRL----------LEILKEVENEKNDKD-----KKIAELESLTLR 756
Query: 628 QLKQKGVKVPPLQQSEAFLTSKS 650
+K + KV L+ ++ K+
Sbjct: 757 HMKDQNKKVANLKHNQQLEKKKN 779
Score = 38.5 bits (88), Expect = 0.020
Identities = 101/480 (21%), Positives = 196/480 (40%), Gaps = 98/480 (20%)
Query: 192 KSICEFDYLRKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEI---QV 248
KS +F + + Q LS S +A Q+ L ++ ++ C +E+ +
Sbjct: 426 KSHSKFMKTKIDQLKQELSKKESELLALQTKLE-------TLSNQNSDCKQHIEVLKESL 478
Query: 249 QKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLS------- 301
K++ +LQ E +AL+++L+ ++ S + +QL D + + G L+
Sbjct: 479 TAKEQRAAILQTEVDALRLRLE-------EKESFLNKKTKQLQDLTEEKGTLAGEIRDMK 531
Query: 302 -LLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEED-EGLEGEPDGVEDTGAW--G 357
+L+ R LQ + +E R K+ L ++ + L+ + + A
Sbjct: 532 DMLEVKERKINVLQKKIENLQEQL---RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEE 588
Query: 358 GVSQMGSVHEEGSEEEEEEEGDRDEDSE----------------ERELPEEEEIP---RR 398
+S+ + E E+ E ++ +R E+ E + EL E+E +
Sbjct: 589 ALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKE 648
Query: 399 RASSLA-----------------ESFEEE---LLAQLEEYEQVILDFQFN------LEAT 432
ASSLA E +EE L AQL++ + D + N ++
Sbjct: 649 HASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQL 708
Query: 433 RTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQ-QLQAMTD---KFSNL 488
S Q +VD L+++ E K++ E L+ M D K +NL
Sbjct: 709 DKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANL 768
Query: 489 R-----EDKKHQEMMGLIEK--DNQLLRQQVSELERKLTKRDCVISELD--------TKV 533
+ E KK+ +++ + + D+ Q ++E + + ELD T+
Sbjct: 769 KHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQ 828
Query: 534 SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQA--EQHTRVA-LESSQSRLERLRNKII 590
S +++ L ++R KQL+E L+ K+E + A E+ +A LE S S+ ++ + +++
Sbjct: 829 SLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVM 888
Score = 30.8 bits (68), Expect = 4.1
Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 220 QSCLRKRMPWYLSVIHEKDHCLSELEIQVQKK---DEEILLLQEEREALKMQLK 270
+ L + L+ I EKD ++ LE+ KK EE++ L+ E++ L QLK
Sbjct: 849 EEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLK 902
Score = 29.6 bits (65), Expect = 9.2
Identities = 35/177 (19%), Positives = 85/177 (48%), Gaps = 22/177 (12%)
Query: 454 ETQLRKINTENETLQKELRERRQQLQAMTDKFSN-----------LREDKKH-----QEM 497
+ QL+++ EN+ L+KEL + +L + + LR+++ +E
Sbjct: 151 QAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQ 210
Query: 498 MGLIEKDNQLLRQQVSELERKL-TKRDC--VISELDTKVSQLQEQVELDQNHLQRWKQLQ 554
M + ++NQ L+ + L+ +L T+RD ++ + +EL + + +R Q +
Sbjct: 211 MRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRR-LQAE 269
Query: 555 EDLQSKK-EMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANEISDND 610
D Q+K+ ++++ + + +E+ + L R++ I+ + +K L ++ ++D
Sbjct: 270 HDRQAKELFLLRKTLEEMELRIETQKQTL-NARDESIKKLLEMLQSKGLPSKSLEDD 325
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 59.7 bits (143), Expect = 8e-09
Identities = 51/217 (23%), Positives = 101/217 (46%), Gaps = 47/217 (21%)
Query: 369 GSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFN 428
GSEE+++EEG+ ED E+R+ RR ++ E+ A+++E +
Sbjct: 387 GSEEDDDEEGEVGEDGEKRK-------KRRGKKKVSPDKMIEMQAKIDEERK-------- 431
Query: 429 LEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNL 488
+L+ ++D +E + K E E +K+L + +Q+ Q++ +K S L
Sbjct: 432 ----------------ALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSAL 475
Query: 489 RED---------KKHQEMMGLIEKDNQLL---RQQVSELERKLTKRDCVISELDTKVSQL 536
+ K +E L+E+ N L R++ +L R+L +++ +++ K + L
Sbjct: 476 EKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSL 535
Query: 537 QEQVELDQNHLQR-WKQLQEDLQSKKEMIQQAEQHTR 572
QE+ + L++ W L + +K EM ++H R
Sbjct: 536 QEEAQGKTKKLKKVWTML---MAAKSEMADLQQEHQR 569
Score = 48.9 bits (115), Expect = 1e-05
Identities = 57/235 (24%), Positives = 104/235 (44%), Gaps = 33/235 (14%)
Query: 301 SLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGE--PDGVEDTGAWG- 357
+LL+ F + EEL+ + EE + D+ G EED+ EGE DG + G
Sbjct: 358 ALLRQFQKEIEELKKKLEEGEEISGS------DISGSEEDDDEEGEVGEDGEKRKKRRGK 411
Query: 358 -GVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEE------- 409
VS + + +EE + + D EE E + +R L ++ +E
Sbjct: 412 KKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEK 471
Query: 410 -------------ELLAQLEEYEQVILDFQFNLEATRTR-YSLATGVIASLQQQVDFQET 455
+LLA+ EE E+++ + LE R R L + Q+++D +E
Sbjct: 472 LSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE- 530
Query: 456 QLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQ 510
+ + E + K+L++ L A + ++L+++ + +E+ GL+E QL R+
Sbjct: 531 KYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQ-REIEGLLENIRQLSRE 584
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 59.7 bits (143), Expect = 8e-09
Identities = 65/282 (23%), Positives = 118/282 (41%), Gaps = 41/282 (14%)
Query: 380 RDEDSEERELPEEEE-------------IPRRRASSLAESFEEELLAQLEEYEQVILD-F 425
RD+D+ +R L EE E + + A+ L + EE+L Q E+++ +
Sbjct: 2257 RDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2316
Query: 426 QFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRE------------ 473
Q EATR + LQQQ + + Q R++ + E + ++L E
Sbjct: 2317 QAVQEATRLKAEAEL-----LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2371
Query: 474 RRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKV 533
R++QL+ + + E+D Q R+Q E+ KL + + E T V
Sbjct: 2372 RQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV 2431
Query: 534 SQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQAT 593
L+ Q + + +R ++ +L+ +KE +QQ + ++ E Q+ +Q
Sbjct: 2432 QTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT---------VQQE 2482
Query: 594 FSISGTKSLANE-ISDNDILEALQRIISERSDYYNQLKQKGV 634
+ T++L +S+ D L +R I + QL Q V
Sbjct: 2483 QLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEV 2524
Score = 52.4 bits (124), Expect = 1e-06
Identities = 89/404 (22%), Positives = 166/404 (41%), Gaps = 20/404 (4%)
Query: 231 LSVIHEKDHCLSELEIQVQKKDEEILLLQEEREALKMQLKCLLKGKGQETSMSPGRREQL 290
L+ I E +E EI +++K+ E L+ E Q + L + Q + R QL
Sbjct: 1839 LAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1898
Query: 291 SDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGE-PDG 349
AS L + E+ L+ Q++EE A + E G E E G
Sbjct: 1899 RKASDS----ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSN 1954
Query: 350 VEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEE 409
EDT +++ + + EEE E+ ++ L EEE R+R ++L E E
Sbjct: 1955 AEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE--VE 2012
Query: 410 ELLAQLEEYEQVILDFQFNLEATRTRYSLATGVIASLQQQVDFQETQLRKINTENETLQK 469
L A++EE + L + E+ R LQ + ++ + + + LQ+
Sbjct: 2013 RLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAE---EKAHAFAVQQKEQELQQ 2067
Query: 470 ELRERRQQL-QAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELER-KLTKRDCVIS 527
L++ + L Q + + R ++ +E E++ R+QV E ER K + + +
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2127
Query: 528 ELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRN 587
+ + + + E +Q +R + Q L+ K+ + E+H + A E + + ++
Sbjct: 2128 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA-EQTLRQKAQVEQ 2186
Query: 588 KIIQATFSISGTKSLANEISDNDILEALQRIISERSDYYNQLKQ 631
++ + T N + E LQR+ +E ++ Q Q
Sbjct: 2187 ELTTLRLQLEETDHQKNLLD-----EELQRLKAEATEAARQRSQ 2225
Score = 46.6 bits (109), Expect = 7e-05
Identities = 98/455 (21%), Positives = 197/455 (43%), Gaps = 65/455 (14%)
Query: 204 RKSQTLSPVTSSSVASQSCLRKRM-PWYLSVIHEKDHCLSELEIQVQKKD---EEILLLQ 259
+++ L + +A Q L ++M + + E +E E+ Q+K+ E+ LQ
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2347
Query: 260 EEREALKMQLKCLLKGKGQETSMSPGRREQLSDAS----LKLGRLSLLKAFSRHEEELQH 315
E++E + QL + +G + ++ R+ QL ++ LKL + +A +R EE+ Q
Sbjct: 2348 EDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 316 WWQMQEESAAPERGKEPDLGGGEED---EGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEE 372
+ + EE E+ +L E+ + LE + + + E +E
Sbjct: 2406 FRKQAEEIG--EKLHRTELATQEKVTLVQTLEIQRQQSDHDAE--------RLREAIAEL 2455
Query: 373 EEEEEGDRDE------DSEERELPEEEEIPRRRASSLAESF--EEELLAQLEEY------ 418
E E+E + E SEE + ++E++ + +L +SF E++ L Q E +
Sbjct: 2456 EREKEKLQQEAKLLQLKSEEMQTVQQEQL-LQETQALQQSFLSEKDSLLQRERFIEQEKA 2514
Query: 419 --EQVILDF-----QFNLEATRTRYSLATG---VIASLQQQVDFQETQLRKINTENETLQ 468
EQ+ D Q E R + + ++AS+++ Q + + E LQ
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ 2574
Query: 469 KELRERRQQLQAMTDKFSNLREDKK--HQEMMGLIEKDNQLLRQQVSELERKLTKRDCVI 526
+ ++RRQQ + + ++ LRE + ++ + ++ QV+ + RD
Sbjct: 2575 QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDA-- 2632
Query: 527 SELDTKVSQLQEQVELD--QNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLER 584
LD ++ + + D + + + + + S +E+ + A+ HT V +R E
Sbjct: 2633 --LDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTV---DELARRED 2687
Query: 585 LRNKIIQATFSISG--TKSLANEISDNDILEALQR 617
+R+ +Q SI+G K+ ++S + ALQR
Sbjct: 2688 VRH-YLQGRSSIAGLLLKATNEKLS---VYAALQR 2718
Score = 43.5 bits (101), Expect = 6e-04
Identities = 48/210 (22%), Positives = 91/210 (43%), Gaps = 26/210 (12%)
Query: 373 EEEEEGDRDEDSEERELPEEEEIPRRRASSLAESFEEELLAQLEEYEQVILDFQFNLEAT 432
EEEE + +EERE E E + LAE+ + AQ E EA
Sbjct: 1345 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEA-HAQAKAQAER------------EAK 1391
Query: 433 RTRYSLATGVIASLQQQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDK 492
+ + V+ + VD Q+ + ++Q+EL++ RQ +A + E
Sbjct: 1392 ELQQRMQEEVVRREEAAVDAQQ--------QKRSIQEELQQLRQSSEAEIQAKARQAEAA 1443
Query: 493 KHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRW-K 551
+ + IE++ +++R Q+ ER+ + + L + + + Q Q +R +
Sbjct: 1444 ERSRLR--IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRR 1501
Query: 552 QLQEDLQSKKEMIQQAEQHTRVALESSQSR 581
Q+Q++ Q K++ + E +RV E+ +R
Sbjct: 1502 QVQDESQRKRQ--AEVELASRVKAEAEAAR 1529
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/404 (20%), Positives = 155/404 (38%), Gaps = 60/404 (14%)
Query: 242 SELEIQVQKKDEEI-----LLLQEEREALKMQLKCLLKGKG------------------- 277
SE EIQ + + E L ++EE +++QL+ + +G
Sbjct: 1429 SEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQ 1488
Query: 278 --QETSMSPGRREQLSDASLKLGRL-----SLLKAFSRHEEELQHWWQMQEESAAPERGK 330
Q + R Q+ D S + + S +KA + E Q Q EE
Sbjct: 1489 KRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEA 1548
Query: 331 EPDLGGGEEDEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEGDRDEDSEERELP 390
E L E + + + +T +++ S +E+ + E E+
Sbjct: 1549 ERRLRQAEVERARQVQV--ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606
Query: 391 EEEEIPRRRASSLAESFEEELLAQLEEYE---QVILDFQFNLEATRTRYSLATGVIASLQ 447
EE R + + AE EE +LE ++ L + E + SLA +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666
Query: 448 QQVDFQETQLRKINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLI------ 501
++ + +E + R E Q+EL E+ + Q + + + QE++ L
Sbjct: 1667 EEAE-REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1725
Query: 502 EKDNQLLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKK 561
E+ QLL ++++ L+R+ EL+ ++++++ ++E+ L SK
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEV-------------LLASK- 1771
Query: 562 EMIQQAEQHTRVALESSQSRLERLRNKIIQATFSISGTKSLANE 605
+AE+ +R E S+ RLE + + + ++LA E
Sbjct: 1772 ---ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE 1812
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,191,535
Number of Sequences: 37866
Number of extensions: 1189576
Number of successful extensions: 23708
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 579
Number of HSP's successfully gapped in prelim test: 1163
Number of HSP's that attempted gapping in prelim test: 9578
Number of HSP's gapped (non-prelim): 7362
length of query: 656
length of database: 18,247,518
effective HSP length: 109
effective length of query: 547
effective length of database: 14,120,124
effective search space: 7723707828
effective search space used: 7723707828
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.