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Search of human proteins with 217035107
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform
3 [Homo sapiens]
(462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 944 0.0
gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 937 0.0
gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 937 0.0
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 397 e-110
gi|150417989 cyclin K isoform 1 [Homo sapiens] 77 4e-14
gi|11386183 WAS protein family, member 2 [Homo sapiens] 73 5e-13
gi|160707881 formin 2 [Homo sapiens] 72 1e-12
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 69 7e-12
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 69 7e-12
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 68 2e-11
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 67 4e-11
gi|56549694 enabled homolog isoform a [Homo sapiens] 65 2e-10
gi|39930375 enabled homolog isoform b [Homo sapiens] 65 2e-10
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 65 2e-10
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 65 2e-10
gi|210032580 SET domain containing 1B [Homo sapiens] 65 2e-10
gi|157168329 formin 1 [Homo sapiens] 64 2e-10
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 64 3e-10
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 64 3e-10
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 64 3e-10
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 63 5e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens] 63 5e-10
gi|19923345 RNA binding motif protein 12 [Homo sapiens] 61 2e-09
gi|23510462 RNA binding motif protein 12 [Homo sapiens] 61 2e-09
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 60 3e-09
gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens] 60 4e-09
gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens] 60 4e-09
gi|153792074 proline rich 12 [Homo sapiens] 60 4e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 60 5e-09
gi|18959210 WIRE protein [Homo sapiens] 60 5e-09
>gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform 3
[Homo sapiens]
Length = 462
Score = 944 bits (2441), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 1 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 60
MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS
Sbjct: 1 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 60
Query: 61 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 120
PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA
Sbjct: 61 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 120
Query: 121 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRA 180
NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRA
Sbjct: 121 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRA 180
Query: 181 HSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLS 240
HSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLS
Sbjct: 181 HSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLS 240
Query: 241 SSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDT 300
SSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDT
Sbjct: 241 SSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDT 300
Query: 301 YMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIE 360
YMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIE
Sbjct: 301 YMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIE 360
Query: 361 TLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPS 420
TLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPS
Sbjct: 361 TLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPS 420
Query: 421 RSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 462
RSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH
Sbjct: 421 RSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 462
>gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform 2
[Homo sapiens]
Length = 471
Score = 937 bits (2421), Expect = 0.0
Identities = 462/471 (98%), Positives = 462/471 (98%), Gaps = 9/471 (1%)
Query: 1 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 60
MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS
Sbjct: 1 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 60
Query: 61 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 120
PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA
Sbjct: 61 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 120
Query: 121 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR----- 175
NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR
Sbjct: 121 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV 180
Query: 176 ----IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 231
IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP
Sbjct: 181 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 240
Query: 232 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 291
PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN
Sbjct: 241 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 300
Query: 292 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 351
ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS
Sbjct: 301 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 360
Query: 352 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 411
AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR
Sbjct: 361 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 420
Query: 412 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 462
HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH
Sbjct: 421 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 471
>gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform 1
[Homo sapiens]
Length = 514
Score = 937 bits (2421), Expect = 0.0
Identities = 462/471 (98%), Positives = 462/471 (98%), Gaps = 9/471 (1%)
Query: 1 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 60
MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS
Sbjct: 44 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 103
Query: 61 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 120
PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA
Sbjct: 104 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 163
Query: 121 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR----- 175
NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR
Sbjct: 164 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV 223
Query: 176 ----IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 231
IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP
Sbjct: 224 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 283
Query: 232 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 291
PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN
Sbjct: 284 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 343
Query: 292 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 351
ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS
Sbjct: 344 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 403
Query: 352 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 411
AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR
Sbjct: 404 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 463
Query: 412 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 462
HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH
Sbjct: 464 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 514
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 397 bits (1020), Expect = e-110
Identities = 254/557 (45%), Positives = 313/557 (56%), Gaps = 116/557 (20%)
Query: 1 MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 55
M++GVD IDIYAD EEFNQ+ E+ DQIDLYDDV++ ++ D DR PP V
Sbjct: 1 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60
Query: 56 RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 115
+ P ++YTY+G +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF
Sbjct: 61 GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114
Query: 116 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 175
ENRANGQSKG+A V V SE S KL++LLP + L+G+ V P +Q LSQFE Q+RK
Sbjct: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174
Query: 176 I------------PPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 217
PP SR + GR A P + P A PP P
Sbjct: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234
Query: 218 RPPSALPLMGLPPPPIPP---------PPPLSSS-----------------FGVPP---- 247
PP P +G P PP PP PPPL+ FG PP
Sbjct: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
Query: 248 ------------PPPGIHYQHLMPPPP------------------RLPPHLAVPPPGAIP 277
PPPG PPPP PPHL PPPGA P
Sbjct: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
Query: 278 PALHLNPAFFPPP-------NATVGPPPDTYMKASAPYNHHGSRDSGPPP-------STV 323
PA H+NPAFFPPP + + GPPP PY+ D GPP + +
Sbjct: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG---DYGPPGREMDTARTPL 409
Query: 324 SEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVL 383
SEAEFE+IM RNRAISSSAIS+AVS ASAGDY AIETL+TAI++IKQS+V+ D+RC+VL
Sbjct: 410 SEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVL 469
Query: 384 ISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYF 443
ISSL+DCLHGIE+KSY GS SR R RSRER SRSRE SRRH+ + DRHDDY+
Sbjct: 470 ISSLQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYY 521
Query: 444 QERNREHERHRDRERDR 460
+ER+RE ERHRDR+RDR
Sbjct: 522 RERSRERERHRDRDRDR 538
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 76.6 bits (187), Expect = 4e-14
Identities = 47/103 (45%), Positives = 51/103 (49%), Gaps = 21/103 (20%)
Query: 209 PPSVLPYFNR--------PPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPP 260
PP+ LPY PP P PPP IPPP P G PPPPP + + PP
Sbjct: 467 PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP-----GYPPPPP-TYNPNFPPP 520
Query: 261 PPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVG-----PPP 298
PPRLPP AVPP PP L L PA +PPP G PPP
Sbjct: 521 PPRLPPTHAVPPHP--PPGLGLPPASYPPPAVPPGGQPPVPPP 561
Score = 58.9 bits (141), Expect = 9e-09
Identities = 49/158 (31%), Positives = 64/158 (40%), Gaps = 34/158 (21%)
Query: 177 PPRAHSRDSSDSADGRATPSENLVPSSARVDKPP-SVLPYFNRPPSALPLMGLPPPPIPP 235
PP ++ S ++ + + S + + P LP PP+ LP PP PP
Sbjct: 424 PPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP 483
Query: 236 PPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP----- 290
PPP VPPPP PPP +PP P PG PP NP F PPP
Sbjct: 484 PPP------VPPPPASF-------PPPAIPP----PTPGYPPPPPTYNPNFPPPPPRLPP 526
Query: 291 -NAT-------VGPPPDTYMKASAPYNHHGSRDSGPPP 320
+A +G PP +Y + P G + PPP
Sbjct: 527 THAVPPHPPPGLGLPPASYPPPAVP---PGGQPPVPPP 561
Score = 56.6 bits (135), Expect = 5e-08
Identities = 35/80 (43%), Positives = 40/80 (50%), Gaps = 10/80 (12%)
Query: 209 PPSVLPYFNRPPSALP--LMGLPPPP------IPPPPP-LSSSFGVPP-PPPGIHYQHLM 258
PP P + PP A+P G PPPP PPPPP L + VPP PPPG+
Sbjct: 485 PPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPAS 544
Query: 259 PPPPRLPPHLAVPPPGAIPP 278
PPP +PP P P IPP
Sbjct: 545 YPPPAVPPGGQPPVPPPIPP 564
Score = 52.0 bits (123), Expect = 1e-06
Identities = 43/126 (34%), Positives = 49/126 (38%), Gaps = 45/126 (35%)
Query: 213 LPYFNRPPSALPLMGLPPPPIP---PPPPLSS---------------------------- 241
LP PP A P PPP+P PPPP SS
Sbjct: 396 LPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEG 455
Query: 242 -SFGVPPP---PPGI--HYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVG 295
S+G PP PP ++ H+ PP P PP PPP + PP PA PPP
Sbjct: 456 PSYGALPPAYGPPAHLPYHPHVYPPNPPPPP--VPPPPASFPP-----PAI-PPPTPGYP 507
Query: 296 PPPDTY 301
PPP TY
Sbjct: 508 PPPPTY 513
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 201 PSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPP---PPPGIHYQHL 257
P+ PP+ P F PP LP P +PP PP G+PP PPP +
Sbjct: 502 PTPGYPPPPPTYNPNFPPPPPRLP----PTHAVPPHPP--PGLGLPPASYPPPAVPPGGQ 555
Query: 258 MPPPPRLPPHLAVPPPGAI 276
P PP +PP +PP G +
Sbjct: 556 PPVPPPIPPP-GMPPVGGL 573
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 25/94 (26%)
Query: 219 PPSALPLMGLPPPPIPPP-------PPLSSSFGVPPPPPGIHYQHLMP---PPPRLPPHL 268
PP +P + PP+PP PPL+++ G PP + L PPP P +
Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPV 410
Query: 269 AVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYM 302
PPP +P PPP PPP +YM
Sbjct: 411 HQPPP--LPHR--------PPP-----PPPSSYM 429
Score = 35.8 bits (81), Expect = 0.084
Identities = 45/189 (23%), Positives = 66/189 (34%), Gaps = 28/189 (14%)
Query: 153 EKVDVRPATRQNLSQFEAQARKRIP----PRAHSRDSSDSADGRATPSENLVPSSARVDK 208
+K +PA +Q +Q Q +K P PR R S +E P +++
Sbjct: 304 QKDPQQPAQQQQPAQ---QPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIET 360
Query: 209 PPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSS----FGVPPPPPGIHYQHLMPPPPRL 264
LP + PP P + PP P+ ++ +PPP P P R
Sbjct: 361 THPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP 420
Query: 265 PPHLAVPPPGAIPPALHLNPAFFPPPN--------ATVGP-----PPDTYMKASAPYNHH 311
PP PPP + + ++ T GP PP A PY+ H
Sbjct: 421 PP----PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPH 476
Query: 312 GSRDSGPPP 320
+ PPP
Sbjct: 477 VYPPNPPPP 485
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 16/66 (24%)
Query: 195 PSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHY 254
P L P+ A PP P PP++ P +PP PP PP P PPPG
Sbjct: 520 PPPRLPPTHAVPPHPP---PGLGLPPASYPPPAVPPGGQPPVPP-------PIPPPG--- 566
Query: 255 QHLMPP 260
MPP
Sbjct: 567 ---MPP 569
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 73.2 bits (178), Expect = 5e-13
Identities = 67/211 (31%), Positives = 84/211 (39%), Gaps = 30/211 (14%)
Query: 177 PPRAHSRDSSDS--ADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIP 234
PP A D+ G A P + V S + P P PP P PP P P
Sbjct: 269 PPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH----PPPAPPLGSPPGPKPGFAPPPAPPP 324
Query: 235 PPPPLSSSFGVPPPPPGIHY----QHLMPPPPRLPPH--LAVPPPGAIPPALHLNPAFFP 288
PPPP+ G+PPPPP + + P PP PPH A PPP PPA A +P
Sbjct: 325 PPPPM---IGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA-----ADYP 376
Query: 289 PPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVS 348
T+ PPP + AP GPPP + A+ + AI
Sbjct: 377 ----TLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQP------AIPPPLSDTTKP 426
Query: 349 GASAGDYSDAIETLLTAIAVIKQSRVANDER 379
+S SDA LL+AI Q R ++R
Sbjct: 427 KSSLPAVSDARSDLLSAIRQGFQLRRVEEQR 457
Score = 43.1 bits (100), Expect = 5e-04
Identities = 35/110 (31%), Positives = 39/110 (35%), Gaps = 22/110 (20%)
Query: 235 PPPPLSSSFGVPPPPPGIHYQHLMPPPPRL--------------PPHLAVPPPGAIPPAL 280
PPPP S S P P +L PPP P +V P PPA
Sbjct: 247 PPPPQSDS--ASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAP 304
Query: 281 HL------NPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVS 324
L P F PPP PPP + P GS + PPPS S
Sbjct: 305 PLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPS 354
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 71.6 bits (174), Expect = 1e-12
Identities = 48/119 (40%), Positives = 60/119 (50%), Gaps = 26/119 (21%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPLSSSFGVPPPP--PGIHYQHLMP 259
PP LP PP LP +G+PPPP IPPPPPL + G+PPPP PG+ +P
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGVG----IP 1185
Query: 260 PPPRLPPHLAVPPPGAIP----------PALHLNPAFFPP-PNATVGPPPDTYMKASAP 307
PPP L P + +PPP +P P + + PA PP P G PP + S P
Sbjct: 1186 PPPPL-PGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGP 1243
Score = 71.2 bits (173), Expect = 2e-12
Identities = 54/133 (40%), Positives = 62/133 (46%), Gaps = 29/133 (21%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPLSSSFGVPPPPP----GIHYQHL 257
PP LP PP LP +G+PPPP IPPPPPL + G+PPPPP GI
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGI----- 1140
Query: 258 MPPPPRLPPHLAVPPP-----GAIPPALHLNPAFFPPPNATVG-----PPPDTYMKASAP 307
PPPP L P + +PPP IPP L A PPP G PPP + P
Sbjct: 1141 -PPPPPL-PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPP 1198
Query: 308 YNHHGSRDSGPPP 320
G+ PPP
Sbjct: 1199 PPLPGAGIPPPPP 1211
Score = 68.6 bits (166), Expect = 1e-11
Identities = 47/107 (43%), Positives = 53/107 (49%), Gaps = 22/107 (20%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPLSSSFGVPPPP--PGIHYQHLMP 259
PP LP PP LP G+PPPP IPPPPPL + G+PPPP PG+ +P
Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGVG----IP 1108
Query: 260 PPPRLPPHLAVPPP----GAIPPALHLNPAFFPP----PNATVGPPP 298
PPP LP PPP IPP L A PP P + PPP
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155
Score = 67.4 bits (163), Expect = 3e-11
Identities = 50/117 (42%), Positives = 52/117 (44%), Gaps = 25/117 (21%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPLSSSFGVPPPPP----GIHYQHL 257
PP LP PP LP G+PPPP IPPPPPL G+PPPPP GI
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGVGIPPPPPLPGAGI----- 1118
Query: 258 MPPPPRLPPHLAVPPP----GAIPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 307
PPPP LP PPP IPP L PPP G PPP A P
Sbjct: 1119 -PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP 1174
Score = 66.2 bits (160), Expect = 6e-11
Identities = 51/131 (38%), Positives = 57/131 (43%), Gaps = 19/131 (14%)
Query: 191 GRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPP------IPPPPPL-SSSF 243
G A P +P A + PP + PP LP G+PPPP IPPPPPL +
Sbjct: 950 GAAIPPPPPLPG-AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1008
Query: 244 GVPPPPPGIHYQHLMPPPPRLPPHLAVPPP----GAIPPALHLNPAFFPPPNATVG---P 296
PPP PG +PPPP LP PPP IPP L A PPP G P
Sbjct: 1009 PPPPPLPGAG----IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1064
Query: 297 PPDTYMKASAP 307
PP A P
Sbjct: 1065 PPPPLPGAGIP 1075
Score = 65.5 bits (158), Expect = 1e-10
Identities = 48/114 (42%), Positives = 51/114 (44%), Gaps = 19/114 (16%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPP 260
PP LP PP LP G+PPPP IPPPPPL + PPP PG +PP
Sbjct: 988 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPP 1043
Query: 261 PPRLPPHLAVPPP----GAIPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 307
PP LP PPP IPP L A PPP G PPP A P
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
Score = 65.5 bits (158), Expect = 1e-10
Identities = 48/114 (42%), Positives = 51/114 (44%), Gaps = 19/114 (16%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPP 260
PP LP PP LP G+PPPP IPPPPPL + PPP PG +PP
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPP 1065
Query: 261 PPRLPPHLAVPPP----GAIPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 307
PP LP PPP IPP L A PPP G PPP A P
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP 1119
Score = 63.9 bits (154), Expect = 3e-10
Identities = 41/101 (40%), Positives = 50/101 (49%), Gaps = 18/101 (17%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPLSSSFGVPPPPP----GIHYQHL 257
PP LP PP LP +G+PPPP IPPPPPL + G+PPPPP GI
Sbjct: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGMGI---PP 1219
Query: 258 MPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 298
P PP PP +PPP +P + P P ++ P P
Sbjct: 1220 APAPPLPPPGTGIPPPPLLPVS---GPPLLPQVGSSTLPTP 1257
Score = 62.8 bits (151), Expect = 6e-10
Identities = 47/114 (41%), Positives = 51/114 (44%), Gaps = 19/114 (16%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPP 260
PP LP P LP G+PPPP IPPPPPL + +PPP PG +PP
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG----IPP 977
Query: 261 PPRLPPHLAVPPP----GAIPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 307
PP LP PPP IPP L A PPP G PPP A P
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1031
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/155 (32%), Positives = 61/155 (39%), Gaps = 22/155 (14%)
Query: 171 QARKRIPPRAHSRDSSDSADGRATPSENLVP----SSARVDKPPSVLPYFNRPPSALPLM 226
Q + +PP + P ++P A + PP + PP LP
Sbjct: 903 QGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
Query: 227 GLPPPP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP----GA 275
G+P PP IPPPPPL + PPP PG +PPPP LP PPP
Sbjct: 963 GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPLPGAG 1018
Query: 276 IPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 307
IPP L A PPP G PPP A P
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1053
Score = 61.6 bits (148), Expect = 1e-09
Identities = 51/136 (37%), Positives = 59/136 (43%), Gaps = 17/136 (12%)
Query: 194 TPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIH 253
T S + +P V PP LP P LP IP PPPL + +PPPPP +
Sbjct: 864 TESSSSMPGLGMVPPPPPPLPGMTVPT-------LPSTAIPQPPPLQGTEMLPPPPPPLP 916
Query: 254 YQHLMPPPPRLPPH--LAVPP-PGA-IPPALHLNPAFFPPPNATVG-----PPPDTYMKA 304
+ PPPP LP L +PP PGA IPP L A PPP G PPP
Sbjct: 917 GAGI-PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975
Query: 305 SAPYNHHGSRDSGPPP 320
P G+ PPP
Sbjct: 976 PPPPPLPGAGIPPPPP 991
Score = 47.0 bits (110), Expect = 4e-05
Identities = 34/80 (42%), Positives = 40/80 (50%), Gaps = 17/80 (21%)
Query: 209 PPSVLPYFN-RPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMP--PPPRLP 265
PP LP PP LP MG+PP P PP PP + G+PPPP L+P PP LP
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT--GIPPPP-------LLPVSGPPLLP 1247
Query: 266 P--HLAVPPP---GAIPPAL 280
+P P G +PP L
Sbjct: 1248 QVGSSTLPTPQVCGFLPPPL 1267
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 69.3 bits (168), Expect = 7e-12
Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 15/102 (14%)
Query: 209 PPSVLPYFNRPPSALPLMG----LPPPPIP-------PPPPLSSSFGVPPPPPGIHYQHL 257
PP LP PS L G PPPP+P PPPPL S G+PPPPP + +
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 703
Query: 258 MPP-PPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 298
MPP PP LP +PPP P + P PPP + PPP
Sbjct: 704 MPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGMGMPPPP 742
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 190 DGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPP 249
+G PS + +P + PP + PP PL G P PPPPPL G+PPPP
Sbjct: 650 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP-PPPPPLPGEAGMPPPP 708
Query: 250 PGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP 290
P + +PPPP P +PPP PP + + P PPP
Sbjct: 709 PPLPGGPGIPPPPPFPGGPGIPPP---PPGMGMPP---PPP 743
Score = 60.8 bits (146), Expect = 2e-09
Identities = 45/130 (34%), Positives = 59/130 (45%), Gaps = 27/130 (20%)
Query: 202 SSARVDKPPSVLPYFNRPPSALPLMGLPPPP------IPPPPPLSSSFGVPPPPPGIHYQ 255
S+A + PPSV PS P+ PP P IPPPP S PPPPP
Sbjct: 557 SAAAITVPPSV-------PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP---- 605
Query: 256 HLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP---NATVGPPP--DTYMKASAPYNH 310
PPPP LP + + P ++P ++P PPP +AT+ PPP + +P +
Sbjct: 606 --PPPPPPLPGGVCISSPPSLPGGTAISP---PPPLSGDATIPPPPPLPEGVGIPSPSSL 660
Query: 311 HGSRDSGPPP 320
G PPP
Sbjct: 661 PGGTAIPPPP 670
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 25/134 (18%)
Query: 176 IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPP 235
+PP SR P+ L S + PP PP PPPP PP
Sbjct: 563 VPPSVPSR-------APVPPAPPLPGDSGTIIPPPPAPGDSTTPPP-------PPPPPPP 608
Query: 236 PPPLSSSFGV--PP---------PPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNP 284
PPPL + PP PPP + +PPPP LP + +P P ++P + P
Sbjct: 609 PPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP 668
Query: 285 AFFPPPNATVGPPP 298
P +A + PPP
Sbjct: 669 PPPLPGSARIPPPP 682
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/85 (40%), Positives = 40/85 (47%), Gaps = 17/85 (20%)
Query: 192 RATPSENLVPSSARVDKPPSVLP-YFNRPPSALPLMG---LPPPP-------IPPPPPLS 240
R P +P SA + PP LP PP PL G +PPPP IPPPPP
Sbjct: 677 RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP-- 734
Query: 241 SSFGVPPPPPGIHYQHLMPPPPRLP 265
G+PPPPP + +P P LP
Sbjct: 735 -GMGMPPPPP---FGFGVPAAPVLP 755
Score = 39.7 bits (91), Expect = 0.006
Identities = 31/90 (34%), Positives = 34/90 (37%), Gaps = 31/90 (34%)
Query: 191 GRATPSENLVPSSARVDKPPSVLPY---FNRPPSALP-LMGLPPPP--------IPPPPP 238
G A P +P SAR+ PP LP PP LP G+PPPP IPPPPP
Sbjct: 663 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 722
Query: 239 LSS-------------------SFGVPPPP 249
FGVP P
Sbjct: 723 FPGGPGIPPPPPGMGMPPPPPFGFGVPAAP 752
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 69.3 bits (168), Expect = 7e-12
Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 15/102 (14%)
Query: 209 PPSVLPYFNRPPSALPLMG----LPPPPIP-------PPPPLSSSFGVPPPPPGIHYQHL 257
PP LP PS L G PPPP+P PPPPL S G+PPPPP + +
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712
Query: 258 MPP-PPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 298
MPP PP LP +PPP P + P PPP + PPP
Sbjct: 713 MPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGMGMPPPP 751
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 190 DGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPP 249
+G PS + +P + PP + PP PL G P PPPPPL G+PPPP
Sbjct: 659 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP-PPPPPLPGEAGMPPPP 717
Query: 250 PGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP 290
P + +PPPP P +PPP PP + + P PPP
Sbjct: 718 PPLPGGPGIPPPPPFPGGPGIPPP---PPGMGMPP---PPP 752
Score = 60.8 bits (146), Expect = 2e-09
Identities = 45/130 (34%), Positives = 59/130 (45%), Gaps = 27/130 (20%)
Query: 202 SSARVDKPPSVLPYFNRPPSALPLMGLPPPP------IPPPPPLSSSFGVPPPPPGIHYQ 255
S+A + PPSV PS P+ PP P IPPPP S PPPPP
Sbjct: 566 SAAAITVPPSV-------PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP---- 614
Query: 256 HLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP---NATVGPPP--DTYMKASAPYNH 310
PPPP LP + + P ++P ++P PPP +AT+ PPP + +P +
Sbjct: 615 --PPPPPPLPGGVCISSPPSLPGGTAISP---PPPLSGDATIPPPPPLPEGVGIPSPSSL 669
Query: 311 HGSRDSGPPP 320
G PPP
Sbjct: 670 PGGTAIPPPP 679
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 25/134 (18%)
Query: 176 IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPP 235
+PP SR P+ L S + PP PP PPPP PP
Sbjct: 572 VPPSVPSR-------APVPPAPPLPGDSGTIIPPPPAPGDSTTPPP-------PPPPPPP 617
Query: 236 PPPLSSSFGV--PP---------PPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNP 284
PPPL + PP PPP + +PPPP LP + +P P ++P + P
Sbjct: 618 PPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP 677
Query: 285 AFFPPPNATVGPPP 298
P +A + PPP
Sbjct: 678 PPPLPGSARIPPPP 691
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/85 (40%), Positives = 40/85 (47%), Gaps = 17/85 (20%)
Query: 192 RATPSENLVPSSARVDKPPSVLP-YFNRPPSALPLMG---LPPPP-------IPPPPPLS 240
R P +P SA + PP LP PP PL G +PPPP IPPPPP
Sbjct: 686 RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP-- 743
Query: 241 SSFGVPPPPPGIHYQHLMPPPPRLP 265
G+PPPPP + +P P LP
Sbjct: 744 -GMGMPPPPP---FGFGVPAAPVLP 764
Score = 39.7 bits (91), Expect = 0.006
Identities = 31/90 (34%), Positives = 34/90 (37%), Gaps = 31/90 (34%)
Query: 191 GRATPSENLVPSSARVDKPPSVLPY---FNRPPSALP-LMGLPPPP--------IPPPPP 238
G A P +P SAR+ PP LP PP LP G+PPPP IPPPPP
Sbjct: 672 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 731
Query: 239 LSS-------------------SFGVPPPP 249
FGVP P
Sbjct: 732 FPGGPGIPPPPPGMGMPPPPPFGFGVPAAP 761
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 68.2 bits (165), Expect = 2e-11
Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 18/102 (17%)
Query: 219 PPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPP 278
PP P G PPP PPPPP +S PPPP + PPPP P A PPP P
Sbjct: 277 PPPPPPSRGGPPP--PPPPPHNSG----PPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330
Query: 279 ALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPP 320
++ + P PPPN PPP + +SAP SGPPP
Sbjct: 331 SVAVPP---PPPNRMYPPPPPA-LPSSAP--------SGPPP 360
Score = 67.0 bits (162), Expect = 3e-11
Identities = 50/158 (31%), Positives = 65/158 (41%), Gaps = 22/158 (13%)
Query: 201 PSSARVDKPPSVLPYFNRPPSALPLMGL---PPPPI-------PPPPPLSSSFGVPPPPP 250
P +R PP P N P P G PPPP PPPPP S VPPPPP
Sbjct: 280 PPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP 339
Query: 251 GIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNAT---VGPPPDTYMKASAP 307
Y PPPP LP PP P L + P PPP GPPP + +
Sbjct: 340 NRMYP---PPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDG- 395
Query: 308 YNHHGSRDSGPPPSTVSE----AEFEDIMKRNRAISSS 341
+H +G + + + A+ + + + +R +S S
Sbjct: 396 -DHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCS 432
Score = 52.0 bits (123), Expect = 1e-06
Identities = 37/105 (35%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 177 PPRAHSRDSSDSADGRATPSE--NLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIP 234
PP +S A GR P + P++A PPS PP + PPP +P
Sbjct: 292 PPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALP 351
Query: 235 PPPPLSSSFGVPPPPPGI-HYQHLMPPPPRLPPHLAVPPPGAIPP 278
P G PPPPP + + PPPP PP PPPG PP
Sbjct: 352 SSAP----SGPPPPPPSVLGVGPVAPPPPPPPP----PPPGPPPP 388
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 66.6 bits (161), Expect = 4e-11
Identities = 69/240 (28%), Positives = 96/240 (40%), Gaps = 43/240 (17%)
Query: 82 AAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKL 141
A +++G+ ++ L + GV + K + G SKGYA + AS ++
Sbjct: 100 ANIFIGNLDPEIDEKLLYDTFSAFGVI-LQTPKIMRDPDTGNSKGYAFINFASFDASDAA 158
Query: 142 LELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSENLVP 201
+E +NG+ + RP T A +DS G A +E L+
Sbjct: 159 IE-----AMNGQYLCNRPITVSY---------------AFKKDSKGERHGSA--AERLLA 196
Query: 202 SSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPP 261
+ + L +RP L PPP P P+ SS G PPPG MPPP
Sbjct: 197 AQ-------NPLSQADRPHQ---LFADAPPPPSAPNPVVSSLGSGLPPPG------MPPP 240
Query: 262 PRLPPHLAVPPPGAIPPAL--HLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPP 319
PP VPPPGA+PP + + P PP A GPP A P + H PP
Sbjct: 241 GSFPP--PVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPP 298
Score = 53.5 bits (127), Expect = 4e-07
Identities = 32/81 (39%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 218 RPPSALPLMGLPPPPIPPP-PPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAI 276
RPP +P G PP +PP PP S G P P P + PPP +PPH PP
Sbjct: 336 RPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPP---HGMRGPPPLMPPHGYTGPPRPP 392
Query: 277 PPALHLNPAFFPPPNATVGPP 297
P P PPP T PP
Sbjct: 393 PYGYQRGP--LPPPRPTPRPP 411
Score = 52.0 bits (123), Expect = 1e-06
Identities = 32/83 (38%), Positives = 38/83 (45%), Gaps = 14/83 (16%)
Query: 208 KPPSVLPYFNRPPSALPLMGLP-------PPPIPP-----PPPLSSSFGV--PPPPPGIH 253
+PP +P+ PP +P G P P P+PP PPPL G PP PP
Sbjct: 336 RPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYG 395
Query: 254 YQHLMPPPPRLPPHLAVPPPGAI 276
YQ PPPR P VPP G +
Sbjct: 396 YQRGPLPPPRPTPRPPVPPRGPL 418
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 64.7 bits (156), Expect = 2e-10
Identities = 43/119 (36%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 163 QNLSQFEAQARKRIPPRAHSRDSSDSADG-------RATPSENLVPSSARVDKPPSVLPY 215
+ +S A A P + DSS S G TPS+ + PP LP
Sbjct: 262 RRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLP- 320
Query: 216 FNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPG 274
P A + LPPPP PPPPP S G PPPPP + +PPPP PP +P G
Sbjct: 321 ---PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
Score = 56.2 bits (134), Expect = 6e-08
Identities = 73/316 (23%), Positives = 120/316 (37%), Gaps = 32/316 (10%)
Query: 153 EKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSV 212
E+++ RQ + E R+++ R SS +A N V + +P
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG-- 290
Query: 213 LPYFNRPPSALPLMGL------PPPPIP-PPPPLSSSFGVPPPPPGIHYQHLMPPPPRLP 265
L ++P G+ PPPP P PP P +S +PPPP PPPP
Sbjct: 291 LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPG--------PPPPPPL 342
Query: 266 PHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKA----SAPYNHHGSRDSGPPPS 321
P PPP PP + P PPP A P ++ + + P + +G
Sbjct: 343 PSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLR 402
Query: 322 TVSEAEFEDIMKRNRAIS-SSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERC 380
VS E AI +SA SK +G G L+ ++ + R E+
Sbjct: 403 KVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKG 462
Query: 381 RVLISSLKDCLHGIEAKSYSVGASGSSS---------RKRHRSRERSPSRSRESSRRHRD 431
+ + K+ G +++ + AS +S+ R + +SP SR S R
Sbjct: 463 STIETEQKED-KGEDSEPVTSKASSTSTPEPTRKPWERTNTMNGSKSPVISRRDSPRKNQ 521
Query: 432 LLHNEDRHDDYFQERN 447
++ + +D + ++
Sbjct: 522 IVFDNRSYDSLHRPKS 537
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 64.7 bits (156), Expect = 2e-10
Identities = 43/119 (36%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 163 QNLSQFEAQARKRIPPRAHSRDSSDSADG-------RATPSENLVPSSARVDKPPSVLPY 215
+ +S A A P + DSS S G TPS+ + PP LP
Sbjct: 262 RRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLP- 320
Query: 216 FNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPG 274
P A + LPPPP PPPPP S G PPPPP + +PPPP PP +P G
Sbjct: 321 ---PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
Score = 53.9 bits (128), Expect = 3e-07
Identities = 50/173 (28%), Positives = 69/173 (39%), Gaps = 24/173 (13%)
Query: 153 EKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSV 212
E+++ RQ + E R+++ R SS +A N V + +P
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG-- 290
Query: 213 LPYFNRPPSALPLMGL------PPPPIP-PPPPLSSSFGVPPPPPGIHYQHLMPPPPRLP 265
L ++P G+ PPPP P PP P +S +PPPP PPPP
Sbjct: 291 LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPG--------PPPPPPL 342
Query: 266 PHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGP 318
P PPP PP + P PPP PPP + AS + S D+ P
Sbjct: 343 PSTGPPPPPPPPPLPNQVPP--PPP-----PPPAPPLPASGFFLASMSEDNRP 388
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 64.7 bits (156), Expect = 2e-10
Identities = 34/80 (42%), Positives = 39/80 (48%), Gaps = 14/80 (17%)
Query: 219 PPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPP 278
PP+A PL G+ PPP PP PPL +PPPPP + +PPPP P PPP
Sbjct: 551 PPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPP----- 605
Query: 279 ALHLNPAFFPPPNATVGPPP 298
PPP V PPP
Sbjct: 606 ---------PPPLGGVPPPP 616
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/85 (41%), Positives = 40/85 (47%), Gaps = 10/85 (11%)
Query: 227 GLPPPPIPPPPPLSSSFGVPPPPPGIHY---QHLMPPPPRLPPHLAVPPPGAIPPALHLN 283
G+P PP PP P G PPPPP L PPPP LP + +PPP PP L
Sbjct: 547 GIPGPPAAPPLP---GVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPP-PPLLFGG 602
Query: 284 PAFFPPPNATVGPPPDTYMKASAPY 308
P PPP G PP + + PY
Sbjct: 603 P---PPPPPLGGVPPPPGISLNLPY 624
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 18/92 (19%)
Query: 199 LVPSSARVDKPPSVLPYFN----RPPSALPLMG---LPPPPIPPPPPLSSSFGVPPPPPG 251
++ SS+ + PP+ P PP A PL G LPPPP PP P + G+PPPPP
Sbjct: 541 VLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP-PPLPGM---MGIPPPPPP 596
Query: 252 IHYQHLMPPPPRLPPHLAVPPPGAIPPALHLN 283
L PP PP VPP PP + LN
Sbjct: 597 ---PLLFGGPPPPPPLGGVPP----PPGISLN 621
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/51 (50%), Positives = 32/51 (62%), Gaps = 9/51 (17%)
Query: 219 PPSALP-LMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHL 268
PP LP +MG+PP PPPPPL FG PPPPP + +PPPP + +L
Sbjct: 580 PPPPLPGMMGIPP---PPPPPL--LFGGPPPPPPLGG---VPPPPGISLNL 622
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 64.7 bits (156), Expect = 2e-10
Identities = 34/80 (42%), Positives = 39/80 (48%), Gaps = 14/80 (17%)
Query: 219 PPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPP 278
PP+A PL G+ PPP PP PPL +PPPPP + +PPPP P PPP
Sbjct: 551 PPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPP----- 605
Query: 279 ALHLNPAFFPPPNATVGPPP 298
PPP V PPP
Sbjct: 606 ---------PPPLGGVPPPP 616
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/85 (41%), Positives = 40/85 (47%), Gaps = 10/85 (11%)
Query: 227 GLPPPPIPPPPPLSSSFGVPPPPPGIHY---QHLMPPPPRLPPHLAVPPPGAIPPALHLN 283
G+P PP PP P G PPPPP L PPPP LP + +PPP PP L
Sbjct: 547 GIPGPPAAPPLP---GVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPP-PPLLFGG 602
Query: 284 PAFFPPPNATVGPPPDTYMKASAPY 308
P PPP G PP + + PY
Sbjct: 603 P---PPPPPLGGVPPPPGISLNLPY 624
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 18/92 (19%)
Query: 199 LVPSSARVDKPPSVLPYFN----RPPSALPLMG---LPPPPIPPPPPLSSSFGVPPPPPG 251
++ SS+ + PP+ P PP A PL G LPPPP PP P + G+PPPPP
Sbjct: 541 VLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP-PPLPGM---MGIPPPPPP 596
Query: 252 IHYQHLMPPPPRLPPHLAVPPPGAIPPALHLN 283
L PP PP VPP PP + LN
Sbjct: 597 ---PLLFGGPPPPPPLGGVPP----PPGISLN 621
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/51 (50%), Positives = 32/51 (62%), Gaps = 9/51 (17%)
Query: 219 PPSALP-LMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHL 268
PP LP +MG+PP PPPPPL FG PPPPP + +PPPP + +L
Sbjct: 580 PPPPLPGMMGIPP---PPPPPL--LFGGPPPPPPLGG---VPPPPGISLNL 622
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 64.7 bits (156), Expect = 2e-10
Identities = 39/98 (39%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Query: 199 LVPSSARVDKPPSVLPYFNRPPSALPLMGLPP-PPIPPPPPLSSSFGVPPP-------PP 250
+ P +A V P + P PP G PP PP PPPPP F +PPP PP
Sbjct: 662 VTPGAAAVAAPSVLAPTLPLPPPP----GFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPP 717
Query: 251 GIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP 288
H +PPPP LP VPPP +PP P FP
Sbjct: 718 PAHPAVTVPPPP-LPAPPGVPPPPILPPLPPFPPGLFP 754
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/130 (35%), Positives = 54/130 (41%), Gaps = 15/130 (11%)
Query: 178 PRAHSRDSSDSADGRATP-SENLVPS----SARVDKPPSVLPYFNRPPSALPLMGLPPPP 232
P + D + G S++ +PS SA KP V P A P + P P
Sbjct: 623 PTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTP--GAAAVAAPSVLAPTLP 680
Query: 233 IPPP---PPLSSSFGVPPPPPGIHYQHLMPPPPRLPP--HLAVPPPGAIPPALHLNPAFF 287
+PPP PPL PPP PG +PPPP PP H AV P PP L P
Sbjct: 681 LPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVP---PPPLPAPPGVP 737
Query: 288 PPPNATVGPP 297
PPP PP
Sbjct: 738 PPPILPPLPP 747
Score = 36.2 bits (82), Expect = 0.064
Identities = 29/79 (36%), Positives = 35/79 (44%), Gaps = 10/79 (12%)
Query: 208 KPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPH 267
+PP +LP +PP LP P PP PPP P ++ P PP + P P L
Sbjct: 1269 EPPMMLPLPLQPP--LPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGS 1326
Query: 268 LA-------VP-PPGAIPP 278
LA VP PG PP
Sbjct: 1327 LAKSQSTETVPATPGGEPP 1345
Score = 33.1 bits (74), Expect = 0.55
Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 3/71 (4%)
Query: 231 PPIPPPPPLSSSFGVPPPPPGIHYQHLMPP-PPRLPPHLAVPPPGAIPPALHLNPAFFPP 289
PP+ P V P PP + L PP PP PP PPP P + PP
Sbjct: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPE--PETTDASHPSVPP 1309
Query: 290 PNATVGPPPDT 300
PP T
Sbjct: 1310 EPLAEDHPPHT 1320
Score = 32.7 bits (73), Expect = 0.71
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 23/100 (23%)
Query: 177 PPRAHSRDSSDSAD----GRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGL---- 228
P +A +DS+ A +ATP+ + + P + P P+A G
Sbjct: 367 PFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSG 426
Query: 229 ------PPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPP 262
PPP+PP PL+ P PPG PPPP
Sbjct: 427 EFRRAPAPPPLPPAEPLAKE--KPGTPPG-------PPPP 457
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 29/98 (29%)
Query: 227 GLPPPPIPPPPPLSSSFGVPPPP------PGIH-----YQHLM---PPPPRLPPHLA--- 269
G PP P S++F PPP PG YQ + PPPP P A
Sbjct: 362 GSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFG 421
Query: 270 ---------VPPPGAIPPALHLNPAFFPPPNATVGPPP 298
P P +PPA P P GPPP
Sbjct: 422 ARDSGEFRRAPAPPPLPPA---EPLAKEKPGTPPGPPP 456
Score = 31.2 bits (69), Expect = 2.1
Identities = 41/149 (27%), Positives = 48/149 (32%), Gaps = 34/149 (22%)
Query: 174 KRIPPRAHSRDS------SDSADGRAT---PSENLVPSSARVDKPPSVLPYFNRPPSALP 224
+R PP S D + +A GR P + P P +V F P
Sbjct: 1480 RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAP 1539
Query: 225 LMGLPPPPIPPPPPLS---------------SSFGVPPPPPG-----IHYQHLMPP--PP 262
LPP P PPPPP S +PP P G Y L P
Sbjct: 1540 PPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPW 1599
Query: 263 RLPP---HLAVPPPGAIPPALHLNPAFFP 288
R PP H + PP P P F P
Sbjct: 1600 RRPPKKRHEDLVPPAGSPELSPPQPLFRP 1628
Score = 29.3 bits (64), Expect = 7.9
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 26/119 (21%)
Query: 187 DSADGRATPSE-NLVPSSARVDKP-PSVLPYFNRPPSA---LPLMGL---PPPPIPPPPP 238
+ AD R P E L A + P P RPP + P L P PP+ P P
Sbjct: 1218 EPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP 1277
Query: 239 LSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPP 297
L PP PP P PPR P + PP A H P+ P P A PP
Sbjct: 1278 LQ-----PPLPP--------PRPPRPP---SPPPEPETTDASH--PSVPPEPLAEDHPP 1318
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 64.3 bits (155), Expect = 2e-10
Identities = 45/133 (33%), Positives = 53/133 (39%), Gaps = 23/133 (17%)
Query: 177 PPRAHS--RDSSDSADGRATPSENLVPSSARVDKPPSVLPY----FNRPPSALPLMGLPP 230
PP H + +G A+ + +P PP LP + P P+ PP
Sbjct: 620 PPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPP 679
Query: 231 --PPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP 288
PP PPPPPL PPPP PPPP LP A P PG PPA P
Sbjct: 680 LPPPPPPPPPLPPPSSAGPPPP--------PPPPPLPNSPAPPNPGGPPPAP-------P 724
Query: 289 PPNATVGPPPDTY 301
PP PPP +
Sbjct: 725 PPGLAPPPPPGLF 737
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/146 (33%), Positives = 63/146 (43%), Gaps = 28/146 (19%)
Query: 189 ADGRATPSENLVPSSARVDKPPSVLP---YFNRPPSALPLMG--------LPPPP--IPP 235
++ + T S LVP + + P + + + P+ G LPPPP IPP
Sbjct: 595 SESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPP 654
Query: 236 PPPLSSSFG-VPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATV 294
PPPL S G + P PP MPP PP +PPP PP L + PPP
Sbjct: 655 PPPLPSGLGSLSPAPP-------MPPVSAGPP---LPPPPPPPPPLPPPSSAGPPP---- 700
Query: 295 GPPPDTYMKASAPYNHHGSRDSGPPP 320
PPP + AP N G + PPP
Sbjct: 701 PPPPPPLPNSPAPPNPGGPPPAPPPP 726
Score = 45.4 bits (106), Expect = 1e-04
Identities = 44/171 (25%), Positives = 62/171 (36%), Gaps = 36/171 (21%)
Query: 134 SENSVHKLLELLPGKVLNGEKVDVRP--------ATRQNLSQFEAQARKRIPPRAHSRDS 185
SE+ + +L+P K+ + P A Q + + +K +PP S
Sbjct: 595 SESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPP 654
Query: 186 SD---SADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSS 242
S G +P+ + P SA PP P PP P PPP PPPPPL +S
Sbjct: 655 PPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP----PPPLPPPSSAGPPPPPPPPPLPNS 710
Query: 243 FG----------------VPPPPPGIHY-----QHLMPPPPRLPPHLAVPP 272
PPPPPG+ + P P + P + P
Sbjct: 711 PAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
Length = 588
Score = 63.9 bits (154), Expect = 3e-10
Identities = 70/254 (27%), Positives = 91/254 (35%), Gaps = 39/254 (15%)
Query: 208 KPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPH 267
KPP P+F PP A P LPPPP PPPP S+ PPPGI + PPP PP
Sbjct: 340 KPP---PFF--PPGAPPTH-LPPPPFLPPPPTVSTAPPLIPPPGI---PITVPPPGFPPP 390
Query: 268 LAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAE 327
PPP IP + + + +A P Y + P+ GS S PS V ++
Sbjct: 391 PGAPPPSLIPTIESGHSSGYDSRSARAFP----YGNVAFPH-LPGSAPSW--PSLVDTSK 443
Query: 328 FEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSL 387
D R + D + R ER R S
Sbjct: 444 QWDYYARREKDRDRERDRDRERDRDRD----------------RERERTRERERERDHSP 487
Query: 388 KDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERN 447
+ + + Y +RHR+ SRE RHR+ H E + R+
Sbjct: 488 TPSVFNSDEERYRYREYAERGYERHRA-------SREKEERHRERRHREKEETRHKSSRS 540
Query: 448 REHERHRDRERDRH 461
RH E D H
Sbjct: 541 NSRRRHESEEGDSH 554
Score = 58.9 bits (141), Expect = 9e-09
Identities = 81/355 (22%), Positives = 125/355 (35%), Gaps = 83/355 (23%)
Query: 141 LLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSENLV 200
L ++ G+ N EK P+T+ + + + +PP SR+S+ S +T S
Sbjct: 218 LFKVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPP---SRNSTSSQSQTSTASRKAN 274
Query: 201 PSSA----RVDKPPSVLPYFNRPPSALPLMG-------------------LPPPPIPPPP 237
S R + S P R P A+ ++G +
Sbjct: 275 SSVGKWQDRYGRAES--PDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSAT 332
Query: 238 PLSSSFGVPPP--PPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVG 295
+ ++F PPP PPG HL PPPP LPP PP + P PPP +
Sbjct: 333 EVDNNFSKPPPFFPPGAPPTHL-PPPPFLPP----------PPTVSTAPPLIPPPGIPIT 381
Query: 296 PPPDTYMKASAPYNHHGSRDSGPPPS---TVSEAEFEDIMKRN-RAISSSAISKAVSGAS 351
PP + PPPS T+ R+ RA ++ S
Sbjct: 382 VPPPGFPPP----------PGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGS 431
Query: 352 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 411
A + ++T ++ + + ER R R R
Sbjct: 432 APSWPSLVDTSKQWDYYARREKDRDRERDR------------------------DRERDR 467
Query: 412 HRSRERSPSRSRESSRRHR---DLLHNEDRHDDYFQERNREHERHR-DRERDRHH 462
R RER +R RE R H + ++++ Y + R +ERHR RE++ H
Sbjct: 468 DRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERH 522
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 10/121 (8%)
Query: 191 GRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPP 250
G SE P R+ + ++ PP + G PPP + PPPP G PPPPP
Sbjct: 6 GDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRG-PPPLMRPPPPFGMMRG-PPPPP 63
Query: 251 GIHYQHLMPPPPRLPPHLAVPPPGAIPPAL---HL-NPAFFPPPNATVGPPPDTYMKASA 306
+ P P +PP +PPPG IPP + HL P F PPP +++ PPP
Sbjct: 64 RPPFGR-PPFDPNMPP---MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM 119
Query: 307 P 307
P
Sbjct: 120 P 120
Score = 46.6 bits (109), Expect = 5e-05
Identities = 33/84 (39%), Positives = 41/84 (48%), Gaps = 25/84 (29%)
Query: 209 PPSVLPYFNRPP--SALPLM----GLPPPPIPP--------PPPLSSSFGVPPPPPGIHY 254
PP P F RPP +P M G+PPP PP PPP+SS PPPPG+ +
Sbjct: 60 PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM----PPPPGMMF 115
Query: 255 QHLMPPPPRLPPHLAVPPPGAIPP 278
PP +PP + P A+PP
Sbjct: 116 ------PPGMPP-VTAPGTPALPP 132
Score = 35.4 bits (80), Expect = 0.11
Identities = 61/309 (19%), Positives = 98/309 (31%), Gaps = 53/309 (17%)
Query: 48 STEPPPPVRQEPSPKP------------------NNKTPAILYTYSGLRNRRAAVYVGSF 89
S+ PPPP P P NKTP Y R R +A
Sbjct: 105 SSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDG 164
Query: 90 SWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLELLPGKV 149
+L ++ + A+ +A Q++ A+ ++ +
Sbjct: 165 VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 224
Query: 150 LNGEKVDVRPATRQNLSQFEAQARKRI--------------PPRAHSRDSSDSADGRATP 195
+ A Q +Q +AQ + ++ P A S +S S T
Sbjct: 225 AQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTS 284
Query: 196 SENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFG-VPPP-----P 249
+ S A+ P+ ++ PS+ + P + P P ++ VP P P
Sbjct: 285 TTTTATSVAQTVSTPTTQ---DQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLP 341
Query: 250 PGIHYQHLMPP------PPRLPPHLAVPPPGAIPPALHLNPAFFPP------PNATVGPP 297
P + + P PP + P VP PG P + P PP P +
Sbjct: 342 PAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAAS 401
Query: 298 PDTYMKASA 306
P T A+A
Sbjct: 402 PATLAGATA 410
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 10/121 (8%)
Query: 191 GRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPP 250
G SE P R+ + ++ PP + G PPP + PPPP G PPPPP
Sbjct: 6 GDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRG-PPPLMRPPPPFGMMRG-PPPPP 63
Query: 251 GIHYQHLMPPPPRLPPHLAVPPPGAIPPAL---HL-NPAFFPPPNATVGPPPDTYMKASA 306
+ P P +PP +PPPG IPP + HL P F PPP +++ PPP
Sbjct: 64 RPPFGR-PPFDPNMPP---MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM 119
Query: 307 P 307
P
Sbjct: 120 P 120
Score = 46.6 bits (109), Expect = 5e-05
Identities = 33/84 (39%), Positives = 41/84 (48%), Gaps = 25/84 (29%)
Query: 209 PPSVLPYFNRPP--SALPLM----GLPPPPIPP--------PPPLSSSFGVPPPPPGIHY 254
PP P F RPP +P M G+PPP PP PPP+SS PPPPG+ +
Sbjct: 60 PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM----PPPPGMMF 115
Query: 255 QHLMPPPPRLPPHLAVPPPGAIPP 278
PP +PP + P A+PP
Sbjct: 116 ------PPGMPP-VTAPGTPALPP 132
Score = 30.4 bits (67), Expect = 3.5
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 12/116 (10%)
Query: 193 ATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGI 252
ATP + VP PP+V +P +A+P PP+ PP G+P P PG+
Sbjct: 326 ATPVQT-VPQPHPQTLPPAVPHSVPQPTTAIPAF----PPVMVPPFRVPLPGMPIPLPGV 380
Query: 253 HYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP--PPNATVGPPPDTYMKASA 306
++ P +A G +P + P P P + P T A+A
Sbjct: 381 AMMQIVSCP--YVKTVATTKTGVLP---GMAPPIVPMIHPQVAIAASPATLAGATA 431
>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
Length = 520
Score = 63.2 bits (152), Expect = 5e-10
Identities = 76/324 (23%), Positives = 109/324 (33%), Gaps = 47/324 (14%)
Query: 147 GKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSD---------SADGRATPSE 197
G+ N EK P+T+ + + + +PP + D +GR +E
Sbjct: 201 GRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANE 260
Query: 198 NLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHL 257
N V F++PP P G PP +PPPP L PPPP +
Sbjct: 261 NSNIQVLSERSATEVDNNFSKPPPFFP-PGAPPTHLPPPPFL-------PPPPTVSTAPP 312
Query: 258 MPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSG 317
+ PPP PP PPP IP + + + +A P Y + P+ GS S
Sbjct: 313 LIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFP----YGNVAFPH-LPGSAPSW 367
Query: 318 PPPSTVSEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVAND 377
PS V ++ D R + D + R
Sbjct: 368 --PSLVDTSKQWDYYARREKDRDRERDRDRERDRDRD----------------RERERTR 409
Query: 378 ERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNED 437
ER R S + + + Y +RHR+ SRE RHR+ H E
Sbjct: 410 ERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA-------SREKEERHRERRHREK 462
Query: 438 RHDDYFQERNREHERHRDRERDRH 461
+ R+ RH E D H
Sbjct: 463 EETRHKSSRSNSRRRHESEEGDSH 486
Score = 35.8 bits (81), Expect = 0.084
Identities = 16/37 (43%), Positives = 24/37 (64%)
Query: 426 SRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 462
+RR +D DR + ++R+RE ER R+RER+R H
Sbjct: 381 ARREKDRDRERDRDRERDRDRDRERERTRERERERDH 417
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 63.2 bits (152), Expect = 5e-10
Identities = 48/139 (34%), Positives = 67/139 (48%), Gaps = 19/139 (13%)
Query: 166 SQFEAQARKRIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPL 225
S+ E Q++K+ +HS +S ++ + P +++ PS ++ PP P PP A PL
Sbjct: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPS--QIQAPPMPGPPPLGPPPAPPL 421
Query: 226 MGLPPPP-IPP-PPPLSSSFGVPPPPPGIH--YQHLMP--PPPRLPPHLAVPPPGAIPPA 279
PP +PP PPP + F PP PG+ L+P PPP PP PP +PP
Sbjct: 422 RPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPG 481
Query: 280 LHLNPAFFPPPNATVGPPP 298
PPP GPPP
Sbjct: 482 --------PPPR---GPPP 489
Score = 56.6 bits (135), Expect = 5e-08
Identities = 46/127 (36%), Positives = 51/127 (40%), Gaps = 18/127 (14%)
Query: 177 PPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLP---PPPI 233
PP A G P L+P +PP P PP LP P PP +
Sbjct: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP---GPPPGLPPGPPPRGPPPRL 491
Query: 234 PPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFF-PPPNA 292
PPP P G+PPP PG M PP +PP L PPG PPA NP PPN
Sbjct: 492 PPPAPP----GIPPPRPG------MMRPPLVPP-LGPAPPGLFPPAPLPNPGVLSAPPNL 540
Query: 293 TVGPPPD 299
P D
Sbjct: 541 IQRPKAD 547
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 9/85 (10%)
Query: 200 VPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMP 259
V ++ V+ LP PS + + +P P PP L + PP + L+
Sbjct: 128 VKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLG 187
Query: 260 ------PPPRLPPHLAVPPPGAIPP 278
PP R PP PPPG PP
Sbjct: 188 HGVPRLPPGRKPPG---PPPGPPPP 209
Score = 31.6 bits (70), Expect = 1.6
Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 258 MPPPPRLPPHLAV---PPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSR 314
+P P P ++ + P PGA PP++ + + PP V P + P G +
Sbjct: 141 LPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILP--LLGHGVPRLPPGRK 198
Query: 315 DSGPPP 320
GPPP
Sbjct: 199 PPGPPP 204
>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/236 (25%), Positives = 96/236 (40%), Gaps = 53/236 (22%)
Query: 122 GQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR------ 175
G G A +V A++ +L + G + G KV + +++ + +R+R
Sbjct: 37 GGELGEAFIVFATDEDA-RLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANL 95
Query: 176 -IPPRAHSRDSSDSADGRAT-------------PSENLVPSSARVDK------------- 208
IPP SR + G ++ PS ++V ++ V +
Sbjct: 96 DIPPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASV 155
Query: 209 ---PPSVLPYFNRPP-------SALPLMGLPPPPIPPPPPLSSSFGVP-----PPPPGIH 253
PP++ F P +A P+ +PPPPIPP P + S +P P PP +
Sbjct: 156 GTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVP 215
Query: 254 YQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYN 309
+PP P +PP +VPP +PP + P PPP V P P + AP N
Sbjct: 216 TLPPVPPVPPIPPVPSVPPMTPLPPMSGM-PPLNPPP---VAPLPAGMNGSGAPMN 267
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/291 (23%), Positives = 102/291 (35%), Gaps = 53/291 (18%)
Query: 70 ILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAE 129
IL + + + ++ + + T ++Q + I V + +N NGQ G A
Sbjct: 532 ILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDN--NGQGLGQAL 589
Query: 130 VVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFE----AQARKRIPPRAHSRDS 185
V +E+ K E L K LNG + V T +++ + E AQ +K + +
Sbjct: 590 VQFKNEDDARKS-ERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPA 648
Query: 186 SDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPP--------- 236
P L PS+ P + LP P SA+ GLP +P
Sbjct: 649 VPGMPNAGLPGVGL-PSAGL---PGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEE 704
Query: 237 --------------PPL--------SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPG 274
PP S++FG P PPPG+ P +P +V G
Sbjct: 705 HAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMP---SVGNSG 761
Query: 275 AIPPALHLN-PAFFPPPNATVGPP-----PDTYMKASAPYNHHGSRDSGPP 319
P L L+ P F PN GP P + SGPP
Sbjct: 762 L--PGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPP 810
>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/236 (25%), Positives = 96/236 (40%), Gaps = 53/236 (22%)
Query: 122 GQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR------ 175
G G A +V A++ +L + G + G KV + +++ + +R+R
Sbjct: 37 GGELGEAFIVFATDEDA-RLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANL 95
Query: 176 -IPPRAHSRDSSDSADGRAT-------------PSENLVPSSARVDK------------- 208
IPP SR + G ++ PS ++V ++ V +
Sbjct: 96 DIPPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASV 155
Query: 209 ---PPSVLPYFNRPP-------SALPLMGLPPPPIPPPPPLSSSFGVP-----PPPPGIH 253
PP++ F P +A P+ +PPPPIPP P + S +P P PP +
Sbjct: 156 GTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVP 215
Query: 254 YQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYN 309
+PP P +PP +VPP +PP + P PPP V P P + AP N
Sbjct: 216 TLPPVPPVPPIPPVPSVPPMTPLPPMSGM-PPLNPPP---VAPLPAGMNGSGAPMN 267
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/291 (23%), Positives = 102/291 (35%), Gaps = 53/291 (18%)
Query: 70 ILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAE 129
IL + + + ++ + + T ++Q + I V + +N NGQ G A
Sbjct: 532 ILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDN--NGQGLGQAL 589
Query: 130 VVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFE----AQARKRIPPRAHSRDS 185
V +E+ K E L K LNG + V T +++ + E AQ +K + +
Sbjct: 590 VQFKNEDDARKS-ERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPA 648
Query: 186 SDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPP--------- 236
P L PS+ P + LP P SA+ GLP +P
Sbjct: 649 VPGMPNAGLPGVGL-PSAGL---PGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEE 704
Query: 237 --------------PPL--------SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPG 274
PP S++FG P PPPG+ P +P +V G
Sbjct: 705 HAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMP---SVGNSG 761
Query: 275 AIPPALHLN-PAFFPPPNATVGPP-----PDTYMKASAPYNHHGSRDSGPP 319
P L L+ P F PN GP P + SGPP
Sbjct: 762 L--PGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPP 810
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 60.5 bits (145), Expect = 3e-09
Identities = 56/168 (33%), Positives = 71/168 (42%), Gaps = 17/168 (10%)
Query: 188 SADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP----PIPPPPPLSSSF 243
S G P +V + P +P PP P G PPP P PPPPP +
Sbjct: 320 SRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTP-RGPPPPGRGGPPPPPPPATGRS 378
Query: 244 G-VPPPPPGIHYQHLMPPPPRLPPHLAV---PPPGAIPPALHLNPAFFPPPNATVGPPPD 299
G +PPPPPG + PPPP PP + P P +PPA L PA P G D
Sbjct: 379 GPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA--LVPAGGLAPGGGRGALLD 436
Query: 300 TYMKASAPYNHHGSRDSG---PPPST---VSEAEFEDIMKRNRAISSS 341
+ G+ +S PPP + + A + KR+RAI SS
Sbjct: 437 QIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSS 484
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/96 (35%), Positives = 39/96 (40%), Gaps = 6/96 (6%)
Query: 232 PIPPPPPLSSSFGVPPPPP--GIHYQHLMPPPPRLPPHLAVPPP---GAIPPALHLNPAF 286
P+PPPPP S P PP G + P PP +P +A PPP G PP P
Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPP-VPLGIAPPPPTPRGPPPPGRGGPPPP 370
Query: 287 FPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPST 322
PP GP P A P PPPS+
Sbjct: 371 PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSS 406
>gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens]
Length = 378
Score = 60.1 bits (144), Expect = 4e-09
Identities = 67/273 (24%), Positives = 101/273 (36%), Gaps = 65/273 (23%)
Query: 84 VYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLE 143
++VG + +L + + GV V E+ + + +G+ + E SV + +
Sbjct: 115 IFVGGIPHNCGETELREYFKKFGV--VTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN 172
Query: 144 LLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSE---NLV 200
+ ++ G+KV+V+ RA RDS A G+ S+ +V
Sbjct: 173 MHFHDIM-GKKVEVK--------------------RAEPRDSKSQAPGQPGASQWGSRVV 211
Query: 201 PSSAR--VDKPPSVLPYFNRP-----PSALPLMGLPPPPI----PPPPPLSSSFGVPPPP 249
P++A +PP P P+ + G PPP PPPPP +S+ V PP
Sbjct: 212 PNAANGWAGQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPP 271
Query: 250 PGIHYQHLMPPPPRLPPHLAVPPPGAI------PPALHLNPAFFPPPNATVG------PP 297
G PPP P PP + PP P PPP AT G PP
Sbjct: 272 GGF------PPPQGFPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPP 325
Query: 298 PDTY----------MKASAPYNHHGSRDSGPPP 320
P + + PY +G P P
Sbjct: 326 PPSQAAPDMSKPPTAQPDFPYGQYGLGSYSPAP 358
>gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]
Length = 407
Score = 60.1 bits (144), Expect = 4e-09
Identities = 65/258 (25%), Positives = 98/258 (37%), Gaps = 53/258 (20%)
Query: 84 VYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLE 143
++VG + +L + + GV V E+ + + +G+ + E SV + +
Sbjct: 115 IFVGGIPHNCGETELREYFKKFGV--VTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN 172
Query: 144 LLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSE---NLV 200
+ ++ G+KV+V+ RA RDS A G+ S+ +V
Sbjct: 173 MHFHDIM-GKKVEVK--------------------RAEPRDSKSQAPGQPGASQWGSRVV 211
Query: 201 PSSAR--VDKPPSVLPYFNRP-----PSALPLMGLPPPPI----PPPPPLSSSFGVPPPP 249
P++A +PP P P+ + G PPP PPPPP +S+ V PP
Sbjct: 212 PNAANGWAGQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPP 271
Query: 250 PGIHYQHLMPPPPRLPPHLAVPPPGAI------PPALHLNPAFFPPPNATVGPPPDTYMK 303
G PPP P PP + PP P PPP AT G P
Sbjct: 272 GGF------PPPQGFPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAP----L 321
Query: 304 ASAPYNHHGSRDSGPPPS 321
A P + D PP+
Sbjct: 322 AFPPPPSQAAPDMSKPPT 339
Score = 31.6 bits (70), Expect = 1.6
Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 9/67 (13%)
Query: 209 PPSVLPY-FNRPPSALPLMGLPPPP--------IPPPPPLSSSFGVPPPPPGIHYQHLMP 259
PP P + PP G PPPP +PPPP + + PPP M
Sbjct: 276 PPQGFPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPPPPSQAAPDMS 335
Query: 260 PPPRLPP 266
PP P
Sbjct: 336 KPPTAQP 342
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 60.1 bits (144), Expect = 4e-09
Identities = 50/163 (30%), Positives = 64/163 (39%), Gaps = 20/163 (12%)
Query: 182 SRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLM---GLP-PPPIP--- 234
S D DS E++ + + +D PP P P PL +P PPP+P
Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP 1440
Query: 235 -------PPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFF 287
P PPL P PPP Q PPPP PP A+P P PP + P+
Sbjct: 1441 SANSNGTPEPPLLEEKPPPTPPPAPTPQP-QPPPPPPPPQPALPSP---PPLVAPTPSSP 1496
Query: 288 PPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFED 330
PPP + PPP M + P + PP + ED
Sbjct: 1497 PPP--PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/130 (33%), Positives = 52/130 (40%), Gaps = 16/130 (12%)
Query: 177 PPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVL-------PYFNRPPSALPLMGLP 229
PP A +D+S + DG VP + PS P P P
Sbjct: 1408 PPLAGPKDTS-TPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466
Query: 230 PPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPP 289
P P PPPPP +P PPP + PPPP LPP PPP A+P P PP
Sbjct: 1467 PQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP----PPPPAMPSP----PPPPPP 1518
Query: 290 PNATVGPPPD 299
A + PP+
Sbjct: 1519 AAAPLAAPPE 1528
Score = 42.4 bits (98), Expect = 9e-04
Identities = 32/103 (31%), Positives = 41/103 (39%), Gaps = 17/103 (16%)
Query: 235 PPPPLSSSFGVPPPPPGIHYQH--------LMPPPPRLPP----HLAVPPPGAIPPALH- 281
PPPP ++ P P G+ + L PPPP+L P H P P A +H
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 282 LNPAFF----PPPNATVGPPPDTYMKASAPYNHHGSRDSGPPP 320
L PA PP PPP ++ A HG + P P
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
Score = 42.0 bits (97), Expect = 0.001
Identities = 49/177 (27%), Positives = 66/177 (37%), Gaps = 42/177 (23%)
Query: 223 LPLMGLPPPPI----------PPPPPLSSSFGV------------------PPPPPGIHY 254
LPL+ LPPPP P P P +S GV PPPPP +
Sbjct: 790 LPLV-LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848
Query: 255 Q---HL-------MPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNAT-VGPPPDTYMK 303
Q HL P PRL P ++ PPGA+ L P P T VGPP
Sbjct: 849 QLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKD 908
Query: 304 ASAPYNHHGSRDSGPPPST-VSEAEFEDIMKRNRAIS-SSAISKAVSGASAGDYSDA 358
+ Y + + P ++ F D + ++ S + + G +A DY A
Sbjct: 909 PAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKA 965
Score = 40.0 bits (92), Expect = 0.004
Identities = 26/73 (35%), Positives = 30/73 (41%), Gaps = 5/73 (6%)
Query: 201 PSSARVDKPPSVLPYFNRPPSALPLMGLPPPPI----PPPPPLSSSFGVPPPPPGIHYQH 256
P A PP V P + PP PL PPP + PPPPP ++ PP P
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPP-PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE 1536
Query: 257 LMPPPPRLPPHLA 269
P P HLA
Sbjct: 1537 DPELPDTRPLHLA 1549
Score = 35.8 bits (81), Expect = 0.084
Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 9/55 (16%)
Query: 188 SADGRATPSENLVPSSARVDKPPSVLPYFNRPPSAL----PLMGLPPPPIPPPPP 238
S G TP L P+ KPP + N P L P PPPP PPPPP
Sbjct: 999 SGAGPETPGLGLDPN-----KPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPP 1048
Score = 32.3 bits (72), Expect = 0.93
Identities = 49/210 (23%), Positives = 67/210 (31%), Gaps = 57/210 (27%)
Query: 159 PATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNR 218
P+ LSQF + + + H+ ++ A P + PSS+ + + +R
Sbjct: 104 PSASSLLSQFRSPSWQTA---MHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSR 160
Query: 219 PPSALPLMGLPPPPIPPP------------------PPLSSSFG---------------- 244
P + L PP PP P + SS G
Sbjct: 161 PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLG 220
Query: 245 ---VPPPPPGIHYQHLMPPPPRLPP---HLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 298
PP PG PPPPR P +L A A +P + A GPPP
Sbjct: 221 PAQTPPYRPG---PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPP 277
Query: 299 --------DTYMKASAPYNHHGSRDSGPPP 320
DT +K Y S PPP
Sbjct: 278 PERALPRQDTVIK---HYQRPASAQPPPPP 304
Score = 30.4 bits (67), Expect = 3.5
Identities = 27/87 (31%), Positives = 29/87 (33%), Gaps = 31/87 (35%)
Query: 224 PLMGLPPPPIPP------PPPLSSSFGVPPPPPGIHYQHLMPPPPRLP------------ 265
P G PPP PP P + G P PG+ PP LP
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDP--NKPPELPSTVNAEPLGLIQ 1031
Query: 266 --PHLAVPPPGAIPPALHLNPAFFPPP 290
PH A PPP PP PPP
Sbjct: 1032 SGPHQAAPPPPPPPP---------PPP 1049
Score = 30.0 bits (66), Expect = 4.6
Identities = 28/105 (26%), Positives = 36/105 (34%), Gaps = 26/105 (24%)
Query: 229 PPPPIPPPPP--LSSSFGV------------PPPPPGIHYQHLMPPPPRLPPHLAVPPPG 274
P PP PPPPP L + F + P ++ P PP PP A+P
Sbjct: 229 PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP--PPERALPRQD 286
Query: 275 AIPPALHLNPAFFPPPNATVGPPPDT-----YMKASAPYNHHGSR 314
+ + PPP PPP Y+ Y G R
Sbjct: 287 TVIKHYQRPASAQPPP-----PPPPAHALQHYLSCGGSYPSMGHR 326
Score = 29.6 bits (65), Expect = 6.0
Identities = 17/39 (43%), Positives = 18/39 (46%), Gaps = 3/39 (7%)
Query: 237 PPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGA 275
PPLS VPP P + L P PP P PP GA
Sbjct: 1305 PPLSPPKSVPPSVPA---RGLQPQPPATPAVPHPPPSGA 1340
Score = 29.6 bits (65), Expect = 6.0
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 9/71 (12%)
Query: 216 FNRPPSALPLMGLPPPPIPP-----PPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAV 270
++RPP + G P+ PPP + + PPP P + PP P A+
Sbjct: 1667 WHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPA---PPPKPETPEKTTSEKPPEQTPETAM 1723
Query: 271 P-PPGAIPPAL 280
P PP P+L
Sbjct: 1724 PEPPAPEKPSL 1734
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 59.7 bits (143), Expect = 5e-09
Identities = 42/118 (35%), Positives = 50/118 (42%), Gaps = 19/118 (16%)
Query: 208 KPPSVLPYFNRPPSALPLMGLPPPPIPPPPP----LSSSFGVPPPPPGIHYQHLMPPPPR 263
+PPS +RPPS PL PPP PP P + + GVPPP PP P
Sbjct: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861
Query: 264 LPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPS 321
L P + PP G +PPA HL PP + A A + SR P PS
Sbjct: 862 LRPQ-SQPPEGPLPPAPHL--------------PPSSTSSAVASSSETSSRLPAPTPS 904
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 51/137 (37%), Gaps = 29/137 (21%)
Query: 177 PPRAHSRDSSDSADGRATPSENLVPSS-----ARVDKPPSVLP-------YFNRPPSALP 224
PP+ R S +G P+ +L PSS A + S LP PPS P
Sbjct: 857 PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGP 916
Query: 225 LMGLPPPP----IPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPAL 280
PPP +P P PPPPP +Q + P P A+P P A+
Sbjct: 917 HKSPTPPPTLHLVPEP-------AAPPPPPPRTFQMVTTPFP------ALPQPKALLERF 963
Query: 281 HLNPAFFPPPNATVGPP 297
H P+ N G P
Sbjct: 964 HQVPSGIILQNKAGGAP 980
Score = 35.4 bits (80), Expect = 0.11
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 4/51 (7%)
Query: 219 PPSALPLMGLPPPPIPPPPPLSSSFG-VPPPPPGIHYQHLM---PPPPRLP 265
PP+ L + PP P PPPPP G V PPP + + P PRLP
Sbjct: 1336 PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLP 1386
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/119 (31%), Positives = 40/119 (33%), Gaps = 29/119 (24%)
Query: 214 PYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP 273
P PP L PPP PPP PPPP G + PPP P P
Sbjct: 1329 PVHQPPPPPATLKVAEPPPRPPP---------PPPPTGQMNGTVDHPPPAAPER---KPL 1376
Query: 274 GAIP--PALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSG----PPPSTVSEA 326
G P P L L + VG P AP R G P P+ V EA
Sbjct: 1377 GTAPHCPRLPLRKTY----RENVGGP-------GAPEGTPAGRARGGSPAPLPAKVDEA 1424
Score = 34.3 bits (77), Expect = 0.24
Identities = 27/116 (23%), Positives = 42/116 (36%), Gaps = 7/116 (6%)
Query: 211 SVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAV 270
+VL PPSA+ ++ P + P P +++ P + P P+ PP ++
Sbjct: 581 TVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLT-------VQPAPQAPPAVST 633
Query: 271 PPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEA 326
P P + P P P A P T + + G PPS A
Sbjct: 634 PLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTA 689
Score = 32.0 bits (71), Expect = 1.2
Identities = 32/116 (27%), Positives = 44/116 (37%), Gaps = 14/116 (12%)
Query: 214 PYFNRPPSALPLMGLPPPPIPPPP--PLSSSFGVPPPPPGIHYQHLMPPPPRLP--PHLA 269
P+ + P S + + PPP P P P++ G+ P P Q P P++P L
Sbjct: 714 PHLSVPASVI--VSAPPPAQDPAPATPVAKGAGLGPQAP--DSQASPAPAPQIPAAAPLK 769
Query: 270 VPPPGAIPPALHLNP----AFFPPPNATVGP--PPDTYMKASAPYNHHGSRDSGPP 319
P P + P H P P P+ T P PP S P + PP
Sbjct: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPP 825
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 59.7 bits (143), Expect = 5e-09
Identities = 58/225 (25%), Positives = 80/225 (35%), Gaps = 57/225 (25%)
Query: 146 PGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRATPSENLVPSSAR 205
P +G D ++R +L + R +P + +S + ++ + P R
Sbjct: 126 PVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRR 185
Query: 206 VDKPPSVLPY-------FNRPPSALPLMGL----------PPPPIPPPP--------PLS 240
+ PP+ LP +NR P G PPP+ PPP P
Sbjct: 186 ANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSG 245
Query: 241 SSFGVPPPP----PGIHYQHLMPP---PPRLPPH--------------LAVPPPGAIPPA 279
S PPPP PG+ P P LP LA PPP + P+
Sbjct: 246 QSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPS 305
Query: 280 LHLN----PAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPP 320
L N PA PP PPP P +G+RD+ PPP
Sbjct: 306 LLSNRPPPPARDPPSRGAAPPPPP-------PVIRNGARDAPPPP 343
Score = 45.8 bits (107), Expect = 8e-05
Identities = 45/148 (30%), Positives = 55/148 (37%), Gaps = 35/148 (23%)
Query: 171 QARKRIPPRAHS--RDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGL 228
++ +P R +S R + G A P S ++PP P PPS G
Sbjct: 271 ESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPP---PPARDPPSR----GA 323
Query: 229 PPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP 288
PPP PPP + + PPPPP PP PP PPP P P
Sbjct: 324 APPP-PPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPP----PPPSRTPAG--------P 370
Query: 289 PPNATVGPPPDTYMKASAPYNHHGSRDS 316
PP PPP P +G RDS
Sbjct: 371 PP-----PPP--------PPLRNGHRDS 385
Score = 32.7 bits (73), Expect = 0.71
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 8/35 (22%)
Query: 226 MGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPP 260
M +PPPP PPP PPPPP H + P
Sbjct: 1 MPIPPPPPPPPG--------PPPPPTFHQANTEQP 27
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,345,299
Number of Sequences: 37866
Number of extensions: 1906309
Number of successful extensions: 33857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 671
Number of HSP's successfully gapped in prelim test: 1218
Number of HSP's that attempted gapping in prelim test: 11304
Number of HSP's gapped (non-prelim): 10656
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.