Search of human proteins with 21630257

Search of human proteins with 21630257

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21630257 Mdm2, transformed 3T3 cell double minute 2, p53
binding protein binding protein [Homo sapiens]
         (904 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21630257 Mdm2, transformed 3T3 cell double minute 2, p53 bind...  1813   0.0  
gi|17978466 cyclin T1 [Homo sapiens]                                   34   0.70 
gi|206597470 neural precursor cell expressed, developmentally do...    34   0.70 
gi|206597468 neural precursor cell expressed, developmentally do...    34   0.70 
gi|23097254 neural precursor cell expressed, developmentally dow...    34   0.70 
gi|206597465 neural precursor cell expressed, developmentally do...    34   0.70 
gi|157694505 LINE-1 type transposase domain containing 1 [Homo s...    34   0.70 
gi|83367077 mucin 16 [Homo sapiens]                                    33   1.2  
gi|156119615 myosin IXA [Homo sapiens]                                 33   1.2  
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       33   1.6  
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       33   1.6  
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        33   1.6  
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        33   1.6  
gi|38788260 bromodomain PHD finger transcription factor isoform ...    32   2.0  
gi|18379328 WW domain-containing adapter with a coiled-coil regi...    32   2.0  
gi|18379332 WW domain-containing adapter with a coiled-coil regi...    32   2.0  
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa...    32   2.7  
gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo sap...    32   2.7  
gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isofo...    32   3.5  
gi|98986457 host cell factor 1 [Homo sapiens]                          32   3.5  
gi|151301154 mucin 6, gastric [Homo sapiens]                           32   3.5  
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]              32   3.5  
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]               32   3.5  
gi|38044112 restin isoform b [Homo sapiens]                            31   4.6  
gi|4506751 restin isoform a [Homo sapiens]                             31   4.6  
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    31   4.6  
gi|19923586 nuclear receptor binding SET domain protein 1 isofor...    31   4.6  
gi|79749430 FRAS1-related extracellular matrix protein 2 precurs...    31   4.6  
gi|4504817 potassium voltage-gated channel, shaker-related subfa...    31   5.9  
gi|148746189 multiple PDZ domain protein [Homo sapiens]                31   5.9  

>gi|21630257 Mdm2, transformed 3T3 cell double minute 2, p53 binding
           protein binding protein [Homo sapiens]
          Length = 904

 Score = 1813 bits (4697), Expect = 0.0
 Identities = 904/904 (100%), Positives = 904/904 (100%)

Query: 1   MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINP 60
           MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINP
Sbjct: 1   MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINP 60

Query: 61  EDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEEC 120
           EDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEEC
Sbjct: 61  EDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEEC 120

Query: 121 LGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKL 180
           LGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKL
Sbjct: 121 LGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKL 180

Query: 181 KDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWR 240
           KDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWR
Sbjct: 181 KDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWR 240

Query: 241 GKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYG 300
           GKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYG
Sbjct: 241 GKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYG 300

Query: 301 PALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTI 360
           PALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTI
Sbjct: 301 PALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTI 360

Query: 361 SNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHS 420
           SNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHS
Sbjct: 361 SNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHS 420

Query: 421 ANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEE 480
           ANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEE
Sbjct: 421 ANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEE 480

Query: 481 CLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSP 540
           CLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSP
Sbjct: 481 CLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSP 540

Query: 541 VEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITL 600
           VEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITL
Sbjct: 541 VEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITL 600

Query: 601 LDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIE 660
           LDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIE
Sbjct: 601 LDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIE 660

Query: 661 YCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDG 720
           YCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDG
Sbjct: 661 YCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDG 720

Query: 721 EVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQ 780
           EVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQ
Sbjct: 721 EVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQ 780

Query: 781 TERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTE 840
           TERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTE
Sbjct: 781 TERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTE 840

Query: 841 TLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEK 900
           TLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEK
Sbjct: 841 TLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEK 900

Query: 901 TSKK 904
           TSKK
Sbjct: 901 TSKK 904


>gi|17978466 cyclin T1 [Homo sapiens]
          Length = 726

 Score = 33.9 bits (76), Expect = 0.70
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 4/73 (5%)

Query: 753 SESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC----PLVPIPSCETPKLATKTSS 808
           ++S E      T  SNH+HHH       +   LPV      P  P  S +T  LA KT S
Sbjct: 501 TKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYS 560

Query: 809 GQKSMHESKTSRQ 821
              S   S ++R+
Sbjct: 561 LSSSFSSSSSTRK 573


>gi|206597470 neural precursor cell expressed, developmentally
           down-regulated 1 isoform c [Homo sapiens]
          Length = 571

 Score = 33.9 bits (76), Expect = 0.70
 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 16/157 (10%)

Query: 697 PVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRL---KRRSKDLNCLYPRKRLVK- 752
           PV +  S L S  ++   GS    E    +L  E  ++   K+ SKD       K+L K 
Sbjct: 360 PVTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKD-----SFKQLAKL 414

Query: 753 -SESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC-PLVPIPSCETPKLATKTSSGQ 810
            +  +ES    T+ +SN   +     KP+ E    + C P +   S   PK+A+  ++G 
Sbjct: 415 VTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGV 474

Query: 811 KSMHESKTSRQIKESRSQK-----HTRILKEVVTETL 842
            S    K +  I  +R          R ++ ++ ETL
Sbjct: 475 ASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 511


>gi|206597468 neural precursor cell expressed, developmentally
           down-regulated 1 isoform b [Homo sapiens]
          Length = 660

 Score = 33.9 bits (76), Expect = 0.70
 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 16/157 (10%)

Query: 697 PVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRL---KRRSKDLNCLYPRKRLVK- 752
           PV +  S L S  ++   GS    E    +L  E  ++   K+ SKD       K+L K 
Sbjct: 449 PVTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKD-----SFKQLAKL 503

Query: 753 -SESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC-PLVPIPSCETPKLATKTSSGQ 810
            +  +ES    T+ +SN   +     KP+ E    + C P +   S   PK+A+  ++G 
Sbjct: 504 VTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGV 563

Query: 811 KSMHESKTSRQIKESRSQK-----HTRILKEVVTETL 842
            S    K +  I  +R          R ++ ++ ETL
Sbjct: 564 ASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 600


>gi|23097254 neural precursor cell expressed, developmentally
           down-regulated 1 isoform b [Homo sapiens]
          Length = 660

 Score = 33.9 bits (76), Expect = 0.70
 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 16/157 (10%)

Query: 697 PVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRL---KRRSKDLNCLYPRKRLVK- 752
           PV +  S L S  ++   GS    E    +L  E  ++   K+ SKD       K+L K 
Sbjct: 449 PVTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKD-----SFKQLAKL 503

Query: 753 -SESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC-PLVPIPSCETPKLATKTSSGQ 810
            +  +ES    T+ +SN   +     KP+ E    + C P +   S   PK+A+  ++G 
Sbjct: 504 VTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGV 563

Query: 811 KSMHESKTSRQIKESRSQK-----HTRILKEVVTETL 842
            S    K +  I  +R          R ++ ++ ETL
Sbjct: 564 ASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 600


>gi|206597465 neural precursor cell expressed, developmentally
           down-regulated 1 isoform a [Homo sapiens]
          Length = 667

 Score = 33.9 bits (76), Expect = 0.70
 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 16/157 (10%)

Query: 697 PVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRL---KRRSKDLNCLYPRKRLVK- 752
           PV +  S L S  ++   GS    E    +L  E  ++   K+ SKD       K+L K 
Sbjct: 456 PVTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKD-----SFKQLAKL 510

Query: 753 -SESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC-PLVPIPSCETPKLATKTSSGQ 810
            +  +ES    T+ +SN   +     KP+ E    + C P +   S   PK+A+  ++G 
Sbjct: 511 VTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGV 570

Query: 811 KSMHESKTSRQIKESRSQK-----HTRILKEVVTETL 842
            S    K +  I  +R          R ++ ++ ETL
Sbjct: 571 ASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 607


>gi|157694505 LINE-1 type transposase domain containing 1 [Homo
           sapiens]
          Length = 865

 Score = 33.9 bits (76), Expect = 0.70
 Identities = 88/346 (25%), Positives = 131/346 (37%), Gaps = 33/346 (9%)

Query: 532 FNIL--NDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRT---GSLPHSSEQ 586
           FNIL  NDF P       L      E      LQ+L  F   K  ++      LP   E 
Sbjct: 264 FNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEI 323

Query: 587 LLGHK----EGPRDSITLLDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVL-TPELSPG 641
             G +    +  RD  TL+D+K      TSDGL    L+ + + K E+   L T E    
Sbjct: 324 NQGGRKYGIQEKRDK-TLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFS 382

Query: 642 KLQVLPFEKASV---CHYHGIEYCLDDRKALERD-----GGFSELQSRLIRYETQTTCTR 693
           +L+ L  E + +       G+E   ++   LE +      G  E ++  +  E + T  +
Sbjct: 383 ELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQ 442

Query: 694 ES-FPVPTVLSPLPSPVVSSDP------GSVPDGEVLQNELRTEVSRLKRRSKDLNCLYP 746
           +S F   T++       ++SD        SV D E  + E        K ++  L     
Sbjct: 443 DSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKA 502

Query: 747 RKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATKT 806
            +R  + E   S L   +G      H V  +  + E +   T      P C T  LA+ +
Sbjct: 503 SRR--QKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTP-CLTLCLASPS 559

Query: 807 SSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHE 852
            S + S  E K       S S   T++ K   TE  KKH    T E
Sbjct: 560 KSLEMSHDEHKKHSHTNLSISTGVTKLKK---TEE-KKHRTLHTEE 601


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 11/156 (7%)

Query: 722  VLQNELRTEVSRLKRRS-KDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQ 780
            + Q    +++S L RR  +D++ + P   L K+  S SL+S     S      V+S  P+
Sbjct: 7937 ISQGFSHSQMSTLMRRGPEDVSWMSP-PLLEKTRPSFSLMSSPATTSPS---PVSSTLPE 7992

Query: 781  TERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTE 840
            +  S P+     P+ S  T  LA  T    KS  E  T+     S +        EV T+
Sbjct: 7993 SISSSPL-----PVTSLLTSGLAKTTDMLHKSS-EPVTNSPANLSSTSVEILATSEVTTD 8046

Query: 841  TLKKHSITETHECFTACSQRLFEISKFYLKDLKTSR 876
            T K H  +         S    E + F L D +TS+
Sbjct: 8047 TEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSK 8082


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 39/176 (22%), Positives = 72/176 (40%), Gaps = 21/176 (11%)

Query: 420  SANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALE 479
            SA  +       ++    ++ T + +L   F   SLP F    I Q++    N Q   L+
Sbjct: 1382 SAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFF--YIPQQDPLKTNSQ---LD 1436

Query: 480  ECLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKM-------ILRKMDKIKTF 532
              ++R KL +  +T   A    +   TR++     D ++P +       +L+K++K+ T 
Sbjct: 1437 TSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNT- 1495

Query: 533  NILNDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLL 588
                     E     L + N  E  E+ + Q  +  EK ++  +T   P   E L+
Sbjct: 1496 -------EKEERQKQLQQQNEKEMMEQ-IRQQTDILEKERKAFKTIEKPRIGECLV 1543


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 15/135 (11%)

Query: 774 VTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRI 833
           ++S +P T    P+  P++P P   +P       S  K   E     Q+++   +  T  
Sbjct: 44  LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSK--EEEGLRAQVRDLEEKLETLR 101

Query: 834 LK----EVVTETLKKHSI---------TETHECFTACSQRLFEISKFYLKDLKTSRGLFE 880
           LK    +   + L+KH I         ++  E      +RL E  K   + L+      E
Sbjct: 102 LKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYME 161

Query: 881 EMKKTANNNAVQVID 895
           EM  TA+   +  +D
Sbjct: 162 EMADTADAIEMATLD 176


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 15/135 (11%)

Query: 774 VTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRI 833
           ++S +P T    P+  P++P P   +P       S  K   E     Q+++   +  T  
Sbjct: 158 LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSK--EEEGLRAQVRDLEEKLETLR 215

Query: 834 LK----EVVTETLKKHSI---------TETHECFTACSQRLFEISKFYLKDLKTSRGLFE 880
           LK    +   + L+KH I         ++  E      +RL E  K   + L+      E
Sbjct: 216 LKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYME 275

Query: 881 EMKKTANNNAVQVID 895
           EM  TA+   +  +D
Sbjct: 276 EMADTADAIEMATLD 290


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 15/135 (11%)

Query: 774 VTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRI 833
           ++S +P T    P+  P++P P   +P       S  K   E     Q+++   +  T  
Sbjct: 44  LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSK--EEEGLRAQVRDLEEKLETLR 101

Query: 834 LK----EVVTETLKKHSI---------TETHECFTACSQRLFEISKFYLKDLKTSRGLFE 880
           LK    +   + L+KH I         ++  E      +RL E  K   + L+      E
Sbjct: 102 LKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYME 161

Query: 881 EMKKTANNNAVQVID 895
           EM  TA+   +  +D
Sbjct: 162 EMADTADAIEMATLD 176


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 15/135 (11%)

Query: 774 VTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRI 833
           ++S +P T    P+  P++P P   +P       S  K   E     Q+++   +  T  
Sbjct: 178 LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSK--EEEGLRAQVRDLEEKLETLR 235

Query: 834 LK----EVVTETLKKHSI---------TETHECFTACSQRLFEISKFYLKDLKTSRGLFE 880
           LK    +   + L+KH I         ++  E      +RL E  K   + L+      E
Sbjct: 236 LKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYME 295

Query: 881 EMKKTANNNAVQVID 895
           EM  TA+   +  +D
Sbjct: 296 EMADTADAIEMATLD 310


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
           [Homo sapiens]
          Length = 2903

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 7/77 (9%)

Query: 752 KSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQK 811
           +  S    LS+T  +SN     V S  PQ         P  P  +CE+   +  T+S Q 
Sbjct: 653 EGRSPVGCLSETPDSSNMAEKKVASELPQD-------VPEEPNKTCESSNTSATTTSIQP 705

Query: 812 SMHESKTSRQIKESRSQ 828
           ++  S +S ++  S+S+
Sbjct: 706 NLENSNSSSELNSSQSE 722


>gi|18379328 WW domain-containing adapter with a coiled-coil region
           isoform 1 [Homo sapiens]
          Length = 647

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 53/215 (24%), Positives = 83/215 (38%), Gaps = 23/215 (10%)

Query: 685 YETQTTCTRESFPVPTVLSPLPS-PVVSSDPGS----VPDGEVLQNELRTEVSRLKRRSK 739
           Y +    T ++  VP  + PL S P VSS P      V  G V Q+  +  V+  K++  
Sbjct: 450 YVSPRISTPQTNTVP--IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGH 507

Query: 740 DLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCET 799
           +   + PR  L +S S  S        SN  +    +  PQ   S   TC L P  +   
Sbjct: 508 EP--VSPRS-LQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS-SARSTCSLTPALAAHF 563

Query: 800 PKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHEC-FTACS 858
            +   K   G  + H  K + +++E      T  + E+ TE     S+    E   T   
Sbjct: 564 SENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE 623

Query: 859 QRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQV 893
           QR+  +           R   +E++K  N N+  V
Sbjct: 624 QRILFL-----------RQQIKELEKLKNQNSFMV 647


>gi|18379332 WW domain-containing adapter with a coiled-coil region
           isoform 3 [Homo sapiens]
          Length = 544

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 53/215 (24%), Positives = 83/215 (38%), Gaps = 23/215 (10%)

Query: 685 YETQTTCTRESFPVPTVLSPLPS-PVVSSDPGS----VPDGEVLQNELRTEVSRLKRRSK 739
           Y +    T ++  VP  + PL S P VSS P      V  G V Q+  +  V+  K++  
Sbjct: 347 YVSPRISTPQTNTVP--IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGH 404

Query: 740 DLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCET 799
           +   + PR  L +S S  S        SN  +    +  PQ   S   TC L P  +   
Sbjct: 405 EP--VSPRS-LQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS-SARSTCSLTPALAAHF 460

Query: 800 PKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHEC-FTACS 858
            +   K   G  + H  K + +++E      T  + E+ TE     S+    E   T   
Sbjct: 461 SENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE 520

Query: 859 QRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQV 893
           QR+  +           R   +E++K  N N+  V
Sbjct: 521 QRILFL-----------RQQIKELEKLKNQNSFMV 544


>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
           sapiens]
          Length = 941

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 50/211 (23%), Positives = 82/211 (38%), Gaps = 23/211 (10%)

Query: 646 LPFEKASVCHYHGIEYCLDDRKALERDGGF--SELQSRLIRY-----ETQTTCTRESFPV 698
           +P  K  +CH HGI   ++D  AL +       + +S++ R+       + TC +     
Sbjct: 422 VPSRKDHMCHPHGI-MIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE 480

Query: 699 PTVLSPLPS--PVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSES- 755
             + S + +   V   D G    G+  + ++RT  S    +   L+   P+K++   E  
Sbjct: 481 SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSS---GKGSILDAKPPKKKVKSREKK 537

Query: 756 -SESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC---PLVPIPSCETPKLATKTSSGQK 811
            S+   S TT  S        S         P      PL P+     P L     SGQ 
Sbjct: 538 MSKEKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSL-----SGQA 592

Query: 812 SMHESKTSRQIKESRSQKHTRILKEVVTETL 842
              +S   R+I+   S+K  R  K  + +TL
Sbjct: 593 KPEDSDCHRKIETCGSRKSERSCKGALYKTL 623


>gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo
           sapiens]
          Length = 911

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 50/211 (23%), Positives = 82/211 (38%), Gaps = 23/211 (10%)

Query: 646 LPFEKASVCHYHGIEYCLDDRKALERDGGF--SELQSRLIRY-----ETQTTCTRESFPV 698
           +P  K  +CH HGI   ++D  AL +       + +S++ R+       + TC +     
Sbjct: 422 VPSRKDHMCHPHGI-MIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE 480

Query: 699 PTVLSPLPS--PVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSES- 755
             + S + +   V   D G    G+  + ++RT  S    +   L+   P+K++   E  
Sbjct: 481 SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSS---GKGSILDAKPPKKKVKSREKK 537

Query: 756 -SESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC---PLVPIPSCETPKLATKTSSGQK 811
            S+   S TT  S        S         P      PL P+     P L     SGQ 
Sbjct: 538 MSKEKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSL-----SGQA 592

Query: 812 SMHESKTSRQIKESRSQKHTRILKEVVTETL 842
              +S   R+I+   S+K  R  K  + +TL
Sbjct: 593 KPEDSDCHRKIETCGSRKSERSCKGALYKTL 623


>gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isoform
           1 [Homo sapiens]
          Length = 1522

 Score = 31.6 bits (70), Expect = 3.5
 Identities = 25/105 (23%), Positives = 42/105 (40%)

Query: 697 PVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESS 756
           P P    PLP P   + P  + D EV ++  +   + L++  K+L  + P         S
Sbjct: 149 PSPPPPPPLPPPQRITGPKPLQDPEVQKHATQILRNMLRQEEKELQDILPLYGDTSQRPS 208

Query: 757 ESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPK 801
           E  LS  +   +      T R P    SL     ++  P  ++P+
Sbjct: 209 EGRLSLDSQEGDSGLDSGTERFPSLSESLMNRNSVLSDPGLDSPR 253


>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score = 31.6 bits (70), Expect = 3.5
 Identities = 43/186 (23%), Positives = 64/186 (34%), Gaps = 8/186 (4%)

Query: 673  GGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVS 732
            G  S+ Q+R     T TT T  +   P    PL  P ++ +PG      V    L ++V 
Sbjct: 1161 GSKSQCQTRQTS-ATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVR 1219

Query: 733  RLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLV 792
                  KDL    P  R   + S+ ++   + G        V         S  VT   +
Sbjct: 1220 LSSPSIKDL----PAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTAL 1275

Query: 793  PIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHE 852
                C +  +    S+     HE+ T+     S +    R+      ET   H    TH 
Sbjct: 1276 EALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCET---HETGTTHT 1332

Query: 853  CFTACS 858
              TA S
Sbjct: 1333 ATTATS 1338


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 31.6 bits (70), Expect = 3.5
 Identities = 28/110 (25%), Positives = 42/110 (38%), Gaps = 5/110 (4%)

Query: 746  PRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATK 805
            P   L  S +S++L S  T  ++   H  TS     E +   T  + P P+       T 
Sbjct: 1669 PTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTV 1728

Query: 806  TSSGQK----SMHESKTSRQI-KESRSQKHTRILKEVVTETLKKHSITET 850
            T+SG      S   +KTS  +   + S  H  +     T     H+ T T
Sbjct: 1729 TTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGT 1778


>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 31.6 bits (70), Expect = 3.5
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 15/138 (10%)

Query: 756 SESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC-----PLVPIPSCETPKLATKTSSGQ 810
           S   LS +   SN         +P T R  P +C     P  P P+  +      + SG+
Sbjct: 488 SHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGR 547

Query: 811 KSMHESKTSRQIKESRSQKHTRILK-EVVTETLKKHSITETHECFT---------ACSQR 860
            + +E     +   +R  K    LK     ++   HS++  HE F+         +  QR
Sbjct: 548 NNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQR 607

Query: 861 LFEISKFYLKDLKTSRGL 878
               S +  +D   ++GL
Sbjct: 608 PHRHSMYVTRDKVRAKGL 625


>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 31.6 bits (70), Expect = 3.5
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 15/138 (10%)

Query: 756 SESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTC-----PLVPIPSCETPKLATKTSSGQ 810
           S   LS +   SN         +P T R  P +C     P  P P+  +      + SG+
Sbjct: 488 SHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGR 547

Query: 811 KSMHESKTSRQIKESRSQKHTRILK-EVVTETLKKHSITETHECFT---------ACSQR 860
            + +E     +   +R  K    LK     ++   HS++  HE F+         +  QR
Sbjct: 548 NNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQR 607

Query: 861 LFEISKFYLKDLKTSRGL 878
               S +  +D   ++GL
Sbjct: 608 PHRHSMYVTRDKVRAKGL 625


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 37/178 (20%), Positives = 81/178 (45%), Gaps = 11/178 (6%)

Query: 721  EVLQNELRTEVS---RLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSR 777
            E+LQN  +T +    +LK   ++ + L      ++ ++ ++  +QT  ++      +T  
Sbjct: 996  EILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKE 1055

Query: 778  KPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEV 837
            K +T  SL  T       +    +L T   +  K++ E   S+++    +QK     KE+
Sbjct: 1056 KTETLASLEDT---KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI 1112

Query: 838  VTETLKKHSITETHECFTACSQRLFEISKFY--LKDLKTSRGLFEEMKKTANNNAVQV 893
              ETLK+ +  ++ +  +A  +   ++++     +D  TS    EE +   NN  +++
Sbjct: 1113 --ETLKQAAAQKSQQ-LSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEM 1167


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 37/178 (20%), Positives = 81/178 (45%), Gaps = 11/178 (6%)

Query: 721  EVLQNELRTEVS---RLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSR 777
            E+LQN  +T +    +LK   ++ + L      ++ ++ ++  +QT  ++      +T  
Sbjct: 1031 EILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKE 1090

Query: 778  KPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEV 837
            K +T  SL  T       +    +L T   +  K++ E   S+++    +QK     KE+
Sbjct: 1091 KTETLASLEDT---KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI 1147

Query: 838  VTETLKKHSITETHECFTACSQRLFEISKFY--LKDLKTSRGLFEEMKKTANNNAVQV 893
              ETLK+ +  ++ +  +A  +   ++++     +D  TS    EE +   NN  +++
Sbjct: 1148 --ETLKQAAAQKSQQ-LSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEM 1202


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 15/47 (31%), Positives = 26/47 (55%)

Query: 779  PQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKES 825
            PQ   S+PV   + P P+ E+ +L  KT    +S  + K ++++ ES
Sbjct: 1100 PQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLES 1146


>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
            [Homo sapiens]
          Length = 2696

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 15/47 (31%), Positives = 26/47 (55%)

Query: 779  PQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKES 825
            PQ   S+PV   + P P+ E+ +L  KT    +S  + K ++++ ES
Sbjct: 1369 PQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLES 1415


>gi|79749430 FRAS1-related extracellular matrix protein 2 precursor
            [Homo sapiens]
          Length = 3169

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 15/40 (37%), Positives = 23/40 (57%)

Query: 253  EISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNIL 292
            +I FP+   KGV+LK      L TD L+   + S D+N++
Sbjct: 1418 DIVFPDVISKGVSLKEGGKVTLTTDLLSTSDLNSPDENLV 1457


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 2/68 (2%)

Query: 766 NSNHYHHHVTSRKPQTERSL-PVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKE 824
           N N+++H  T  + QT+ +   V+CP +P    +  + +T +S G KS +  +    +KE
Sbjct: 562 NFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEY-LEMEEGVKE 620

Query: 825 SRSQKHTR 832
           S   K  +
Sbjct: 621 SLCAKEEK 628


>gi|148746189 multiple PDZ domain protein [Homo sapiens]
          Length = 2041

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 752  KSESSESLLSQTTGNSNHYHHHVTSRK--PQTERSLPVTCPLVPIPSCETPKLATKTSSG 809
            K  SS+SL+   +G+        TSR   P    S P TCP+  IP CET    +K  +G
Sbjct: 1581 KKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPI--IPGCETTIEISKGRTG 1638


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,119,673
Number of Sequences: 37866
Number of extensions: 1609524
Number of successful extensions: 5525
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 5501
Number of HSP's gapped (non-prelim): 62
length of query: 904
length of database: 18,247,518
effective HSP length: 111
effective length of query: 793
effective length of database: 14,044,392
effective search space: 11137202856
effective search space used: 11137202856
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.