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Search of human proteins with 215599065
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215599065 evolutionarily conserved signaling intermediate in
Toll pathway isoform 2 [Homo sapiens]
(296 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215599065 evolutionarily conserved signaling intermediate in ... 610 e-175
gi|20149633 evolutionarily conserved signaling intermediate in T... 547 e-156
gi|215599070 evolutionarily conserved signaling intermediate in ... 75 7e-14
gi|25952134 dispatched A [Homo sapiens] 34 0.13
gi|239752966 PREDICTED: hypothetical protein [Homo sapiens] 30 1.9
gi|109826564 neurofibromin isoform 1 [Homo sapiens] 30 1.9
gi|4557793 neurofibromin isoform 2 [Homo sapiens] 30 1.9
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 30 1.9
gi|169171308 PREDICTED: hypothetical protein [Homo sapiens] 30 3.3
gi|89025853 PREDICTED: hypothetical protein [Homo sapiens] 30 3.3
gi|42657886 PREDICTED: hypothetical protein [Homo sapiens] 30 3.3
gi|42658266 PREDICTED: hypothetical protein [Homo sapiens] 30 3.3
gi|108773787 retinoblastoma 1 [Homo sapiens] 29 5.7
gi|52630419 sterol regulatory element binding transcription fact... 29 5.7
gi|22547195 sterol regulatory element binding transcription fact... 29 5.7
gi|22749483 hypothetical protein LOC253868 [Homo sapiens] 29 5.7
gi|31982943 forkhead box P3 isoform a [Homo sapiens] 28 7.4
gi|54792138 helicase with zinc finger domain [Homo sapiens] 28 7.4
gi|61966741 TMF regulated nuclear protein [Homo sapiens] 28 7.4
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 28 7.4
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 28 9.7
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 28 9.7
gi|191252782 p21-activated kinase 6 [Homo sapiens] 28 9.7
gi|191252780 p21-activated kinase 6 [Homo sapiens] 28 9.7
gi|9910476 p21-activated kinase 6 [Homo sapiens] 28 9.7
gi|13376834 zinc finger and SCAN domain containing 16 [Homo sapi... 28 9.7
>gi|215599065 evolutionarily conserved signaling intermediate in
Toll pathway isoform 2 [Homo sapiens]
Length = 296
Score = 610 bits (1572), Expect = e-175
Identities = 296/296 (100%), Positives = 296/296 (100%)
Query: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE 60
MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE
Sbjct: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE 60
Query: 61 PRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREY 120
PRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREY
Sbjct: 61 PRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREY 120
Query: 121 GVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETE 180
GVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETE
Sbjct: 121 GVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETE 180
Query: 181 FLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSA 240
FLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSA
Sbjct: 181 FLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSA 240
Query: 241 RVTIYQVPLPKDSTGAADPPQPHIVGSGRDAGGVEPLLPDAAGPGVCEEWLGQLRV 296
RVTIYQVPLPKDSTGAADPPQPHIVGSGRDAGGVEPLLPDAAGPGVCEEWLGQLRV
Sbjct: 241 RVTIYQVPLPKDSTGAADPPQPHIVGSGRDAGGVEPLLPDAAGPGVCEEWLGQLRV 296
>gi|20149633 evolutionarily conserved signaling intermediate in Toll
pathway isoform 1 [Homo sapiens]
Length = 431
Score = 547 bits (1409), Expect = e-156
Identities = 266/266 (100%), Positives = 266/266 (100%)
Query: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE 60
MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE
Sbjct: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE 60
Query: 61 PRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREY 120
PRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREY
Sbjct: 61 PRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREY 120
Query: 121 GVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETE 180
GVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETE
Sbjct: 121 GVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETE 180
Query: 181 FLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSA 240
FLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSA
Sbjct: 181 FLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSA 240
Query: 241 RVTIYQVPLPKDSTGAADPPQPHIVG 266
RVTIYQVPLPKDSTGAADPPQPHIVG
Sbjct: 241 RVTIYQVPLPKDSTGAADPPQPHIVG 266
>gi|215599070 evolutionarily conserved signaling intermediate in
Toll pathway isoform 3 [Homo sapiens]
Length = 217
Score = 75.1 bits (183), Expect = 7e-14
Identities = 43/80 (53%), Positives = 50/80 (62%), Gaps = 4/80 (5%)
Query: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE 60
MSWVQATLLARGLCRAWGGTCGAALTGTSISQVP LP+ + AA + +V
Sbjct: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVP--LPK--DSTGAADPPQPHIVGIQSP 56
Query: 61 PRQRPTKALVPFEDLFGQAP 80
+Q P +F + P
Sbjct: 57 DQQAALARHNPARPVFVEGP 76
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/24 (91%), Positives = 23/24 (95%)
Query: 243 TIYQVPLPKDSTGAADPPQPHIVG 266
+I QVPLPKDSTGAADPPQPHIVG
Sbjct: 29 SISQVPLPKDSTGAADPPQPHIVG 52
>gi|25952134 dispatched A [Homo sapiens]
Length = 1524
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 17/71 (23%)
Query: 1 MSWVQATLLARGLCRAWG--GTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSP 58
+SW AT + +CR G GTCG Q+P LP+ L CSA +H +L SP
Sbjct: 1118 ISWAFATFFFQCMCRCLGPQGTCG---------QIP--LPKKLQCSAFSH----ALSTSP 1162
Query: 59 PEPRQRPTKAL 69
+ Q T +
Sbjct: 1163 SDKGQSKTHTI 1173
>gi|239752966 PREDICTED: hypothetical protein [Homo sapiens]
Length = 117
Score = 30.4 bits (67), Expect = 1.9
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 10/83 (12%)
Query: 11 RGLCRAWGGTCGAALTGTSISQVPRR--------LPRGLHCSAAAHSSEQSLVPSPPEPR 62
R CR W T G + G+S V + LPRG C + + +P PE
Sbjct: 5 RWFCRRWNCTPGESCPGSSPLSVGEKVLHSCGGSLPRGPSCKSKRDRRQLPSLPLCPEGE 64
Query: 63 Q--RPTKALVPFEDLFGQAPGGE 83
+ P AL G+ GGE
Sbjct: 65 KGSPPPPALCSSPKASGEGVGGE 87
>gi|109826564 neurofibromin isoform 1 [Homo sapiens]
Length = 2839
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 72 FEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREYGVERDLAVYNQ 131
FE+ + E+++ L+T+ F + K G+ F Y+A R+ + + DL +Y+
Sbjct: 1569 FEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVA-RRFKTGQINGDLLIYHV 1627
Query: 132 LLNIFP 137
LL + P
Sbjct: 1628 LLTLKP 1633
>gi|4557793 neurofibromin isoform 2 [Homo sapiens]
Length = 2818
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 72 FEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREYGVERDLAVYNQ 131
FE+ + E+++ L+T+ F + K G+ F Y+A R+ + + DL +Y+
Sbjct: 1548 FEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVA-RRFKTGQINGDLLIYHV 1606
Query: 132 LLNIFP 137
LL + P
Sbjct: 1607 LLTLKP 1612
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 30.4 bits (67), Expect = 1.9
Identities = 24/58 (41%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 231 LRHMEPDLSARVTIYQVPLPKDSTGAADPPQPHIVGSGRDAGGVEPLLPDAAGPGVCE 288
L EPD SAR T PL TGAA PP P S VE + + AGP E
Sbjct: 3 LSQEEPD-SARGTSEAQPLGPAPTGAAPPPGPG--PSDSPEAAVEKVEVELAGPATAE 57
>gi|169171308 PREDICTED: hypothetical protein [Homo sapiens]
Length = 151
Score = 29.6 bits (65), Expect = 3.3
Identities = 25/71 (35%), Positives = 26/71 (36%), Gaps = 20/71 (28%)
Query: 20 TCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQR----------PTKAL 69
TC AL G P R A SSE S SPP P QR PT+AL
Sbjct: 26 TCSPALAGPPPPSFPER----------AASSEGSPTHSPPHPPQRLQPPVRVVPKPTRAL 75
Query: 70 VPFEDLFGQAP 80
L Q P
Sbjct: 76 STLRQLHVQPP 86
>gi|89025853 PREDICTED: hypothetical protein [Homo sapiens]
Length = 151
Score = 29.6 bits (65), Expect = 3.3
Identities = 25/71 (35%), Positives = 26/71 (36%), Gaps = 20/71 (28%)
Query: 20 TCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQR----------PTKAL 69
TC AL G P R A SSE S SPP P QR PT+AL
Sbjct: 26 TCSPALAGPPPPSFPER----------AASSEGSPTHSPPHPPQRLQPPVRVVPKPTRAL 75
Query: 70 VPFEDLFGQAP 80
L Q P
Sbjct: 76 STLRQLHVQPP 86
>gi|42657886 PREDICTED: hypothetical protein [Homo sapiens]
Length = 151
Score = 29.6 bits (65), Expect = 3.3
Identities = 25/71 (35%), Positives = 26/71 (36%), Gaps = 20/71 (28%)
Query: 20 TCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQR----------PTKAL 69
TC AL G P R A SSE S SPP P QR PT+AL
Sbjct: 26 TCSPALAGPPPPSFPER----------AASSEGSPTHSPPHPPQRLQPPVRVVPKPTRAL 75
Query: 70 VPFEDLFGQAP 80
L Q P
Sbjct: 76 STLRQLHVQPP 86
>gi|42658266 PREDICTED: hypothetical protein [Homo sapiens]
Length = 151
Score = 29.6 bits (65), Expect = 3.3
Identities = 25/71 (35%), Positives = 26/71 (36%), Gaps = 20/71 (28%)
Query: 20 TCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQR----------PTKAL 69
TC AL G P R A SSE S SPP P QR PT+AL
Sbjct: 26 TCSPALAGPPPPSFPER----------AASSEGSPTHSPPHPPQRLQPPVRVVPKPTRAL 75
Query: 70 VPFEDLFGQAP 80
L Q P
Sbjct: 76 STLRQLHVQPP 86
>gi|108773787 retinoblastoma 1 [Homo sapiens]
Length = 928
Score = 28.9 bits (63), Expect = 5.7
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 33 VPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVPFEDL 75
+P + PR +AAA ++E P PP P + P + P EDL
Sbjct: 1 MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGP-EDL 42
>gi|52630419 sterol regulatory element binding transcription factor
1 isoform a [Homo sapiens]
Length = 1177
Score = 28.9 bits (63), Expect = 5.7
Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 5/34 (14%)
Query: 252 DSTGAADPPQPHIVGSGRDAGGVEPLLPDAAGPG 285
D G DPP +G AGG +P PD + PG
Sbjct: 72 DFPGLFDPPY-----AGSGAGGTDPASPDTSSPG 100
>gi|22547195 sterol regulatory element binding transcription factor
1 isoform b [Homo sapiens]
Length = 1147
Score = 28.9 bits (63), Expect = 5.7
Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 5/34 (14%)
Query: 252 DSTGAADPPQPHIVGSGRDAGGVEPLLPDAAGPG 285
D G DPP +G AGG +P PD + PG
Sbjct: 42 DFPGLFDPPY-----AGSGAGGTDPASPDTSSPG 70
>gi|22749483 hypothetical protein LOC253868 [Homo sapiens]
Length = 134
Score = 28.9 bits (63), Expect = 5.7
Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 3/60 (5%)
Query: 12 GLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVP 71
G A GG GA S P L RGLHC S+ P P P P+ L P
Sbjct: 29 GFSEAKGGH-GAPRHSASHGATPSGLRRGLHCREG--PSDSGFQPHPGPPLSVPSGPLAP 85
>gi|31982943 forkhead box P3 isoform a [Homo sapiens]
Length = 431
Score = 28.5 bits (62), Expect = 7.4
Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 6/46 (13%)
Query: 39 RGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVPFEDLFGQAPGGER 84
+G AH+S SL P PP Q PT LV AP G R
Sbjct: 46 QGRDLRGGAHASSSSLNPMPPSQLQLPTLPLVMV------APSGAR 85
>gi|54792138 helicase with zinc finger domain [Homo sapiens]
Length = 1942
Score = 28.5 bits (62), Expect = 7.4
Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 4/54 (7%)
Query: 131 QLLNIFPKEVFRPRNI----IQRIFVHYPRQQECGIAVLEQMENHGVMPNKETE 180
QL E R RN+ + R++ HYP + C I + E +H + N +E
Sbjct: 825 QLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE 878
>gi|61966741 TMF regulated nuclear protein [Homo sapiens]
Length = 227
Score = 28.5 bits (62), Expect = 7.4
Identities = 14/36 (38%), Positives = 18/36 (50%)
Query: 248 PLPKDSTGAADPPQPHIVGSGRDAGGVEPLLPDAAG 283
P P+D ++ PP P + G P LPDAAG
Sbjct: 24 PPPRDPMPSSQPPPPTPTLTPTPTPGQSPPLPDAAG 59
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 28.5 bits (62), Expect = 7.4
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 44 SAAAHSSEQSLVPSPPEPRQRPTKALVPFEDLFGQAPGGE 83
+AAA + S+ +PP P + + LVP + G PGG+
Sbjct: 331 AAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQ 370
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 28.1 bits (61), Expect = 9.7
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
Query: 34 PRRLPRGLHCSAAAHSSEQS-LVPSP-PEPRQRPTKALVPFEDLFGQAPGG 82
PR++P AA SSE + PSP P P Q ++ VP E G+A GG
Sbjct: 170 PRQVP-----GAAGDSSEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGG 215
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo
sapiens]
Length = 443
Score = 28.1 bits (61), Expect = 9.7
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 5/53 (9%)
Query: 13 LCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRP 65
L RA GG+C A L + Q P L +S + +VPS P P P
Sbjct: 26 LRRATGGSCFAGLESFAWPQ-----PASLQSVETQSTSSEEMVPSSPSPPPPP 73
>gi|191252782 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 28.1 bits (61), Expect = 9.7
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 22 GAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVP 71
G+ T S + RRL R + S AA + S P PP P+ +P + P
Sbjct: 245 GSPSPKTRESSLKRRLFRSMFLSTAATAPPSSSKPGPP-PQSKPNSSFRP 293
>gi|191252780 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 28.1 bits (61), Expect = 9.7
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 22 GAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVP 71
G+ T S + RRL R + S AA + S P PP P+ +P + P
Sbjct: 245 GSPSPKTRESSLKRRLFRSMFLSTAATAPPSSSKPGPP-PQSKPNSSFRP 293
>gi|9910476 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 28.1 bits (61), Expect = 9.7
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 22 GAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVP 71
G+ T S + RRL R + S AA + S P PP P+ +P + P
Sbjct: 245 GSPSPKTRESSLKRRLFRSMFLSTAATAPPSSSKPGPP-PQSKPNSSFRP 293
>gi|13376834 zinc finger and SCAN domain containing 16 [Homo
sapiens]
Length = 348
Score = 28.1 bits (61), Expect = 9.7
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 6/54 (11%)
Query: 125 DLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKE 178
DL V Q L+I PK+ + + H+P E + VLE +E P K+
Sbjct: 82 DLLVLEQFLSILPKD------LQAWVRAHHPETGEEAVTVLEDLERELDEPGKQ 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,171,021
Number of Sequences: 37866
Number of extensions: 674280
Number of successful extensions: 2524
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2513
Number of HSP's gapped (non-prelim): 31
length of query: 296
length of database: 18,247,518
effective HSP length: 102
effective length of query: 194
effective length of database: 14,385,186
effective search space: 2790726084
effective search space used: 2790726084
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.