Guide to the Human Genome
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Search of human proteins with 21536411

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
         (482 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]            971   0.0  
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]            961   0.0  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]            953   0.0  
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]            884   0.0  
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]            868   0.0  
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]            867   0.0  
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]            863   0.0  
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]            859   0.0  
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]             853   0.0  
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]           735   0.0  
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                      434   e-122
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                       434   e-122
gi|49472835 bridging integrator 2 [Homo sapiens]                      316   3e-86
gi|8923904 bridging integrator 3 [Homo sapiens]                        57   4e-08
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    54   4e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    51   2e-06
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    50   6e-06
gi|39930351 dynamin binding protein [Homo sapiens]                     49   8e-06
gi|49640014 ubiquitin associated and SH3 domain containing, A sh...    46   7e-05
gi|9507221 ubiquitin associated and SH3 domain containing, A lon...    46   7e-05
gi|109689723 abl interactor 2 [Homo sapiens]                           45   1e-04
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    45   2e-04
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    45   2e-04
gi|153792074 proline rich 12 [Homo sapiens]                            45   2e-04
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             44   2e-04
gi|115527120 nebulin [Homo sapiens]                                    44   3e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                44   4e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    44   4e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                44   4e-04
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                44   4e-04

>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score =  971 bits (2511), Expect = 0.0
 Identities = 482/482 (100%), Positives = 482/482 (100%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA 360
           PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA
Sbjct: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA 360

Query: 361 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 420
           AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY
Sbjct: 361 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 420

Query: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
           TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER
Sbjct: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480

Query: 481 VP 482
           VP
Sbjct: 481 VP 482


>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score =  961 bits (2485), Expect = 0.0
 Identities = 482/497 (96%), Positives = 482/497 (96%), Gaps = 15/497 (3%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345
           EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS
Sbjct: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360

Query: 346 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 405
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420

Query: 406 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 465
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480

Query: 466 LEKCRGVFPENFTERVP 482
           LEKCRGVFPENFTERVP
Sbjct: 481 LEKCRGVFPENFTERVP 497


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score =  953 bits (2464), Expect = 0.0
 Identities = 482/518 (93%), Positives = 482/518 (93%), Gaps = 36/518 (6%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS--------------- 345
           PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS               
Sbjct: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPTESPAGSLPSGEP 360

Query: 346 ---------------------QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVV 384
                                QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVV
Sbjct: 361 SAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVV 420

Query: 385 ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP 444
           ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP
Sbjct: 421 ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP 480

Query: 445 EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 482
           EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 481 EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 518


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score =  884 bits (2284), Expect = 0.0
 Identities = 447/482 (92%), Positives = 453/482 (93%), Gaps = 7/482 (1%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA 360
           PSQ     P   P    PS E    +    F  ++  + +   P+QPAEASEVAGGTQPA
Sbjct: 301 PSQ-----PTESPAGSLPSGEPSAAE--GTFAVSWPSQTAEPGPAQPAEASEVAGGTQPA 353

Query: 361 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 420
           AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY
Sbjct: 354 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 413

Query: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
           TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER
Sbjct: 414 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 473

Query: 481 VP 482
           VP
Sbjct: 474 VP 475


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score =  868 bits (2242), Expect = 0.0
 Identities = 447/513 (87%), Positives = 453/513 (88%), Gaps = 38/513 (7%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 329
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P   P    PS E    +   
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-----PTESPAGSLPSGEPSAAE--G 353

Query: 330 LFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA 389
            F  ++  + +   P+QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA
Sbjct: 354 TFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA 413

Query: 390 TVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDE 449
           TVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDE
Sbjct: 414 TVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDE 473

Query: 450 GWLMGVKESDWNQHKELEKCRGVFPENFTERVP 482
           GWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 474 GWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506


>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score =  867 bits (2239), Expect = 0.0
 Identities = 462/593 (77%), Positives = 466/593 (78%), Gaps = 111/593 (18%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 329
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360

Query: 330 LFEDTFVPEISVTTPSQ---PAEASEVAG------------------------------- 355
           LFEDTFVPEISVTTPSQ   P   SE A                                
Sbjct: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420

Query: 356 -GTQPAAGAQEPGETA------------------------ASEAASSSLPA--------- 381
             T+  AG+   GE +                        ASE A  + PA         
Sbjct: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480

Query: 382 ------------VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 429
                       VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540

Query: 430 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 482
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593


>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
          Length = 439

 Score =  863 bits (2230), Expect = 0.0
 Identities = 439/482 (91%), Positives = 439/482 (91%), Gaps = 43/482 (8%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA 360
           P                                           SQPAEASEVAGGTQPA
Sbjct: 301 P-------------------------------------------SQPAEASEVAGGTQPA 317

Query: 361 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 420
           AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY
Sbjct: 318 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 377

Query: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
           TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER
Sbjct: 378 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 437

Query: 481 VP 482
           VP
Sbjct: 438 VP 439


>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score =  859 bits (2220), Expect = 0.0
 Identities = 453/550 (82%), Positives = 458/550 (83%), Gaps = 68/550 (12%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV------------PPPPKHT 317
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P             P PP  +
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360

Query: 318 PSKEVK---QEQILSLFEDTFVPEISVTT----------------------PSQPAEASE 352
           P K      Q     L+E T  P  S+ +                      P+QPAEASE
Sbjct: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420

Query: 353 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 412
           VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480

Query: 413 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 472
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540

Query: 473 FPENFTERVP 482
           FPENFTERVP
Sbjct: 541 FPENFTERVP 550


>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
          Length = 454

 Score =  853 bits (2204), Expect = 0.0
 Identities = 439/497 (88%), Positives = 439/497 (88%), Gaps = 58/497 (11%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345
           EPAGGATPGATLPKSP                                           S
Sbjct: 301 EPAGGATPGATLPKSP-------------------------------------------S 317

Query: 346 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 405
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 377

Query: 406 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 465
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 378 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 437

Query: 466 LEKCRGVFPENFTERVP 482
           LEKCRGVFPENFTERVP
Sbjct: 438 LEKCRGVFPENFTERVP 454


>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
          Length = 409

 Score =  735 bits (1897), Expect = 0.0
 Identities = 385/482 (79%), Positives = 389/482 (80%), Gaps = 73/482 (15%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKS                                   
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKS----------------------------------- 265

Query: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA 360
                     P PP  +P+                 PEI V    +PA            
Sbjct: 266 ----------PSPPDGSPAA---------------TPEIRVNHEPEPA------------ 288

Query: 361 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 420
            G   PG T     + SSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY
Sbjct: 289 -GGATPGATLPKSPSQSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 347

Query: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
           TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER
Sbjct: 348 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 407

Query: 481 VP 482
           VP
Sbjct: 408 VP 409


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score =  434 bits (1117), Expect = e-122
 Identities = 216/339 (63%), Positives = 261/339 (76%), Gaps = 4/339 (1%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 307
           T++  PSD+ P +  K+PSPP + SP  +P    NH   P   A+P    P+SPSQ RKG
Sbjct: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300

Query: 308 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 346
           PPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339



 Score =  111 bits (277), Expect = 2e-24
 Identities = 76/241 (31%), Positives = 110/241 (45%), Gaps = 28/241 (11%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
           P  +A A      S  +G+P    E      P   G +   A   K  ++  +G     P
Sbjct: 427 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 483

Query: 314 PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAA 371
                   V QE++        +P + +    +PA   E  G  +   GA+  E  E AA
Sbjct: 484 EAEELEATVPQEKV--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAA 531

Query: 372 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 420
               +S  P +  E  P             G  D           LPPGF++KV+  HD+
Sbjct: 532 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 591

Query: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
            A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R
Sbjct: 592 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 651

Query: 481 V 481
           +
Sbjct: 652 L 652


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score =  434 bits (1117), Expect = e-122
 Identities = 216/339 (63%), Positives = 261/339 (76%), Gaps = 4/339 (1%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 307
           T++  PSD+ P +  K+PSPP + SP  +P    NH   P   A+P    P+SPSQ RKG
Sbjct: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300

Query: 308 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 346
           PPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339



 Score =  111 bits (277), Expect = 2e-24
 Identities = 76/241 (31%), Positives = 110/241 (45%), Gaps = 28/241 (11%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
           P  +A A      S  +G+P    E      P   G +   A   K  ++  +G     P
Sbjct: 469 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 525

Query: 314 PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAA 371
                   V QE++        +P + +    +PA   E  G  +   GA+  E  E AA
Sbjct: 526 EAEELEATVPQEKV--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAA 573

Query: 372 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 420
               +S  P +  E  P             G  D           LPPGF++KV+  HD+
Sbjct: 574 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 633

Query: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
            A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R
Sbjct: 634 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 693

Query: 481 V 481
           +
Sbjct: 694 L 694


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score =  316 bits (809), Expect = 3e-86
 Identities = 186/405 (45%), Positives = 248/405 (61%), Gaps = 25/405 (6%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAE G  G  AG  A  VQKK +RAQEKVLQKLGKA ETKDE+FEQ   NF +Q  EG +
Sbjct: 1   MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           L KDL+ +L++VK MHE+SK+++E LQE+Y  +W G +E   I  NNDLLW DY +KL D
Sbjct: 60  LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE  K
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQ VFE++N +L EELP L+NSR+G YV  FQ+I+ L + F++EMSKLN NL +V+  LE
Sbjct: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239

Query: 241 KQHGSNTFTVKAQPSDN------APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGA--- 291
           KQH +  F VK   S +      +P     + S P  SP +   + +  E E        
Sbjct: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299

Query: 292 TPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQE--QILSLFEDTFVPEISVTTPSQPAE 349
            P A   +  S+++         +    +E+++E  +  S  ED  +P  +    +QP+ 
Sbjct: 300 APDAAQGEDNSEIK---------ELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSP 350

Query: 350 ASEVAGGTQ---PAAGAQEP-GETAASEAASSSLPAVVVETFPAT 390
            +E A   +   P++    P G  + S   SSS   VV+ T  A+
Sbjct: 351 TTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTAS 395


>gi|8923904 bridging integrator 3 [Homo sapiens]
          Length = 253

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)

Query: 53  KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
           +QL E TR LQKD++    +  AM +++ K++  L    + E D   +D  N + A +  
Sbjct: 32  QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88

Query: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
           +  MD ++Q+ V+Q   T+   L +F    P +   + +R + L DY   +   E  +  
Sbjct: 89  MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148

Query: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
           +K     AK+ +A EEL   ++ FE  N  L EE+P  + SR+ ++  +F+S+   +  +
Sbjct: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208

Query: 222 HKEMSKLNQNLNDVL 236
           + EM K+  +L+  L
Sbjct: 209 YSEMHKIFGDLSHQL 223


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 62/237 (26%), Positives = 90/237 (37%), Gaps = 37/237 (15%)

Query: 214 IAGLEENFHKEMSKLNQNLNDVLVG-----LEKQHGSNTFTVKAQPSDNAPAKGNKSPSP 268
           ++G EE   +E   L+ + N+V  G         + S+T ++ +  ++ A   G   P P
Sbjct: 710 VSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKP 769

Query: 269 P-----DGSPAATP-----EIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTP 318
           P     DG P   P     +I    EP PA  AT   T P +P      PPV P      
Sbjct: 770 PATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVP------ 823

Query: 319 SKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 378
            KE K+E      E    P +      +P  A E+A  T     A+EP ++  +E A   
Sbjct: 824 -KEEKEE------ETAAAPPVEEGEEQKPPAAEELAVDT---GKAEEPVKSECTEEAEEG 873

Query: 379 -LPAVVVETFPATVNGTV-----EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 429
                  E   AT  G +     EGGSG        G      +    +A + DE +
Sbjct: 874 PAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAE 930


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 41/132 (31%), Positives = 50/132 (37%), Gaps = 21/132 (15%)

Query: 254  PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
            P   AP     +P  P G PA +P         P G  TP A  P SP    KG P  PP
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSP---------PKGAPTPPAATPPSP----KGSPGTPP 1328

Query: 314  PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ---PAEASEVAGGTQPAAGAQEPGETA 370
            PK  P+        ++       P +  TTPS    P   S   G T PAA     G  A
Sbjct: 1329 PKGAPTPPA-----VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383

Query: 371  ASEAASSSLPAV 382
             +  +    PA+
Sbjct: 1384 MTPPSPKRGPAI 1395



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 40/145 (27%), Positives = 49/145 (33%), Gaps = 32/145 (22%)

Query: 252  AQPSDN-APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV 310
            A PS   AP     +P  P G PA          P P G  TP A  P SP    KG P 
Sbjct: 955  ATPSPKWAPTPPAATPPSPKGGPAT---------PSPKGAPTPPAATPPSP----KGGPA 1001

Query: 311  PPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGG--TQPAAGAQEPGE 368
             P PK  P+                 P ++  +P     A+    G  T PAA    P  
Sbjct: 1002 TPSPKGAPTP----------------PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045

Query: 369  TAASEAASSSLPAVVVETFPATVNG 393
            + A+       P     T P+   G
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGG 1070



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/146 (30%), Positives = 52/146 (35%), Gaps = 20/146 (13%)

Query: 244  GSNTFTVKAQPSDNAPAKGNKSPSPPDG--SPAATPEIRVNH--EPEPAGGATPGATLPK 299
            G+ T      PS   P  G  +PSP     +PAATP         P P G  T  A  P 
Sbjct: 1193 GAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249

Query: 300  SPSQLRKGPPVPPPPKHTPSKEVKQEQI----LSLFEDTFVPEISVTTPSQPAEASEVAG 355
            SP    KG P  PPPK  P+            L+       P  +V TP  P    +   
Sbjct: 1250 SP----KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP----KGGP 1301

Query: 356  GTQPAAGA-QEPGETAASEAASSSLP 380
             T P  GA   P  T  S   S   P
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTP 1327



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 41/140 (29%), Positives = 50/140 (35%), Gaps = 30/140 (21%)

Query: 252  AQPSDN-APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV 310
            A PS   AP     +P  P GSPAATP         P G +TP A  P SP   +  P  
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPF--------PKGASTPPAATPPSP---KGSPAA 1049

Query: 311  PPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTP-SQPAEASEVAGGTQPAAGAQEP-GE 368
             P PK  P+                 P  ++ +P   PA  S     T PAA    P G 
Sbjct: 1050 TPLPKGAPT----------------TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093

Query: 369  TAASEAASSSLPAVVVETFP 388
             A      + +P       P
Sbjct: 1094 PATPSPKGAPMPPAATPPSP 1113



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 28/130 (21%)

Query: 258  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 317
            APA    S SP        P+  +   P P G  TP A  P SP    KG P  P PK  
Sbjct: 908  APALSMTSSSPKKARATPAPK-GIPASPSPKGAPTPPAATPPSP----KGGPATPSPKWA 962

Query: 318  PSKEVKQEQILSLFEDTFVPEISVTTPSQ---PAEASEVAGGTQPAAGAQEP--GETAAS 372
            P+                    + T PS    PA  S     T PAA    P  G    S
Sbjct: 963  PTPP------------------AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004

Query: 373  EAASSSLPAV 382
               + + PAV
Sbjct: 1005 PKGAPTPPAV 1014



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 41/158 (25%), Positives = 52/158 (32%), Gaps = 30/158 (18%)

Query: 254  PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
            P   AP     +P  P GSP           P P G  TP A  P SP      P   P 
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGT---------PPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 314  PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASE 373
             K  P+    +E                  P+ PA      GG      + + G    S 
Sbjct: 1356 SKGGPTTPSSKE-----------------GPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398

Query: 374  AASSSLPAVV---VETFPATVNGTVEGGSGAGRLDLPP 408
                + PAV+    +  PAT   T EG +   + DL P
Sbjct: 1399 KGDPTSPAVIPLSPKKAPAT-PVTREGAATPSKGDLTP 1435



 Score = 36.2 bits (82), Expect = 0.068
 Identities = 40/145 (27%), Positives = 55/145 (37%), Gaps = 23/145 (15%)

Query: 259  PAKGNKSP---SPPDGSPAATPEIRVNHEPEPAGGATP----GATLPKSPSQLRKGPPV- 310
            P KG  +P   +PP  SP  TP +         G  TP    G T P +    + GP + 
Sbjct: 1328 PPKGAPTPPAVTPP--SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 311  PPPPKH-----TPSKEVKQEQILSLFED----TFVPEISVTTPSQ----PAEASEVAGGT 357
            PP PK      +P  +     ++ L       T V      TPS+    P   + V+   
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 358  QPAAGAQEPGETAASEAASSSLPAV 382
             PA  A + G    S     +LPAV
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAV 1470



 Score = 35.8 bits (81), Expect = 0.089
 Identities = 42/162 (25%), Positives = 57/162 (35%), Gaps = 7/162 (4%)

Query: 244  GSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGG-ATP----GATLP 298
            G  T ++K  P+  A    +    P   SP   P       P P GG ATP      T P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 299  KSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQ 358
             +     KG    PPPK  P+              T  P+ + TTP+    + +    T 
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189

Query: 359  PAAGA-QEPGETAASEAASSSLPAVV-VETFPATVNGTVEGG 398
               GA   P  T  S     + P+     T PA    + +GG
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 40/129 (31%), Positives = 50/129 (38%), Gaps = 31/129 (24%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
           P ++   +G+K       SP  TP       P P G  TP A  P SP    KG  +PP 
Sbjct: 837 PENSLSFQGSKDSPATTHSP--TP-------PSPKGAPTPSAVTPLSP----KGVTLPPK 883

Query: 314 PKHTPS-------KE------VKQEQILSLFEDTFVPEISVTTPSQ---PAEASEVAGGT 357
              TPS       KE       KQ   LS+   +  P+ +  TP+    PA  S     T
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS--PKKARATPAPKGIPASPSPKGAPT 941

Query: 358 QPAAGAQEP 366
            PAA    P
Sbjct: 942 PPAATPPSP 950



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 42/158 (26%), Positives = 51/158 (32%), Gaps = 27/158 (17%)

Query: 254  PSDNAPAKGNKSPSPPDG------------SPAATPEIRVN--HEPEPAGGATPGATLPK 299
            P   AP     +P  P G            +PAATP         P P G  T  A  P 
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203

Query: 300  SPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQP 359
            SP    KG    P PK  P+              T  P+ + TTP+    + +    T P
Sbjct: 1204 SP----KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259

Query: 360  AAGAQEP---------GETAASEAASSSLPAVVVETFP 388
              GA  P         G  A      +  PAVV    P
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 40/169 (23%), Positives = 63/169 (37%), Gaps = 37/169 (21%)

Query: 249  TVKAQPSDNAPAKGNKSPS------------PPDGSPAATPEIRVNHEPE-------PAG 289
            ++K  P+ +AP  G  +PS            P    P A  ++  +  P+       P G
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 290  GATPGATLPKSPSQLRKGP-----PVPPP----PKHTPSKEVKQEQILSLFEDTFVPE-- 338
              T  A +P SP ++   P     P+ P      K TP+    +E ++        P+  
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 339  ISVTTPSQ-PAEASEVAGGTQPAA------GAQEPGETAASEAASSSLP 380
             ++ TP + PA  S     + PA       GA  P E     A +S  P
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP 1610



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 42/191 (21%), Positives = 63/191 (32%), Gaps = 33/191 (17%)

Query: 251  KAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPE---PAGG-ATPGATL-PKSPSQLR 305
            K  P+     +G  +PS  D +P A   + +   P    P GG ATP +   P  P+   
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472

Query: 306  KGPPVPPPPKHT-------------------------PSKEVKQEQILSLFEDTFVPEIS 340
              P  PP PK                           PS   +     S   D   P  +
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532

Query: 341  VTTPSQPAEASEVAGGTQPAAGAQEPGETAA---SEAASSSLPAVVVETFPATVNGTVEG 397
            + +   PA  +       PA     P +T A    + A ++  +    + PA    T +G
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592

Query: 398  GSGAGRLDLPP 408
                  L +PP
Sbjct: 1593 APSPKELLIPP 1603



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 44/169 (26%), Positives = 58/169 (34%), Gaps = 29/169 (17%)

Query: 247  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHE----PEPAGGATPGATLPK--- 299
            T   K  P+  AP +    P+    SP  TP I    E    P     ++P A  P    
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591

Query: 300  ---SPSQLRKGPPV--------PPPPKHTPSKEVKQEQILSLFEDTFVPEISVT----TP 344
               SP +L   P V        P PP  TP    K     +       P ++ +    +P
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651

Query: 345  SQPAEASEVAGGTQPAAGAQEP---GETAASEA----ASSSLPAVVVET 386
            + PA  +   G T P A    P   G TA  E     A  S P +   T
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPT 1700


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 59/229 (25%), Positives = 87/229 (37%), Gaps = 34/229 (14%)

Query: 219 ENFHKEMSKLNQNLNDVLVGLEK--QHGSNTFTVKAQPSDNAPAKGNKSPSPP-----DG 271
           E+   E S ++ N  +++   E    + S+T ++ +  ++ A   G   P PP     DG
Sbjct: 701 EDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADG 760

Query: 272 SPAATP-----EIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQ 326
            P   P     +I    EP PA  AT   T P +P      PPV P       KE K+E 
Sbjct: 761 PPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVP-------KEEKEE- 812

Query: 327 ILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSS-LPAVVVE 385
                E    P +      +P  A E+A  T     A+EP ++  +E A          E
Sbjct: 813 -----ETAAAPPVEEGEEQKPPAAEELAVDT---GKAEEPVKSECTEEAEEGPAKGKDAE 864

Query: 386 TFPATVNGTV-----EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 429
              AT  G +     EGGSG        G      +    +A + DE +
Sbjct: 865 AAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAE 913


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 50/223 (22%), Positives = 90/223 (40%), Gaps = 18/223 (8%)

Query: 17   NVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKA-- 74
            ++ KK  R    +    G A + KDE FE+  +NF  Q        +DL  YL  ++   
Sbjct: 996  SIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESA 1055

Query: 75   ---MHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLG 131
               +  A    + C++  +  D    +  ++    +D L+ ++ ++     +  ++  L 
Sbjct: 1056 CVKVVAAVSMWDVCMERGHR-DLEQFERVHRYI--SDQLFTNFKERTERLVISPLNQLLS 1112

Query: 132  QFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVD 191
             F      + KR  KL+D+ +     E L         K  K  EEL  A+  +E +N  
Sbjct: 1113 MFTGPHKLVQKRFDKLLDFYNCTERAEKL---------KDKKTLEELQSARNNYEALNAQ 1163

Query: 192  LQEELPSLWNSRVGFYVNTFQSIAGLEENF-HKEMSKLNQNLN 233
            L +ELP       G + N     A    +F H+ + +L   L+
Sbjct: 1164 LLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLS 1206



 Score = 35.8 bits (81), Expect = 0.089
 Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 15/81 (18%)

Query: 399 SGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 458
           S +    +P   M + +A    +A   +EL  + GDV+ +I    P     GW  G    
Sbjct: 135 SQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP-----GWFEG---- 185

Query: 459 DWNQHKELEKCRGVFPENFTE 479
                 ELE  RG+FPE F E
Sbjct: 186 ------ELEGRRGIFPEGFVE 200



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 15/68 (22%)

Query: 414 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 473
           V+A  D+  + ++EL L  GD++ V+        DE WL+G KE             G F
Sbjct: 7   VRAIFDFCPSVSEELPLFVGDIIEVLAV-----VDEFWLLGKKED----------VTGQF 51

Query: 474 PENFTERV 481
           P +F E V
Sbjct: 52  PSSFVEIV 59


>gi|49640014 ubiquitin associated and SH3 domain containing, A short
           form [Homo sapiens]
          Length = 623

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 414 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 473
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 243 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 293

Query: 474 PENFTER 480
           PEN+T+R
Sbjct: 294 PENYTDR 300


>gi|9507221 ubiquitin associated and SH3 domain containing, A long
           form [Homo sapiens]
          Length = 661

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 414 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 473
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 281 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 331

Query: 474 PENFTER 480
           PEN+T+R
Sbjct: 332 PENYTDR 338


>gi|109689723 abl interactor 2 [Homo sapiens]
          Length = 475

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 60/237 (25%), Positives = 81/237 (34%), Gaps = 55/237 (23%)

Query: 265 SPSPPDGSPAATPEI------RVNHEPEPAGGATPGATLPKSPSQ------LRKGP---- 308
           +PSPP   P    +          H P   GG+ P    P   SQ      +  GP    
Sbjct: 269 TPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQ 328

Query: 309 -PV---PPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ 364
            PV   PPPP      +V  +  L  F       IS T P  P     V   + P     
Sbjct: 329 NPVSLAPPPPSIL---QVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPP 385

Query: 365 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATD 424
           E  E   +     S P    E  P                  P  ++ KV A +DYT   
Sbjct: 386 EDYEEEEAAVVEYSDP--YAEEDPPWA---------------PRSYLEKVVAIYDYTKDK 428

Query: 425 TDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 481
            DEL  + G ++ VI     ++ D+GW  GV          +    G+FP N+ E +
Sbjct: 429 EDELSFQEGAIIYVI-----KKNDDGWYEGV----------MNGVTGLFPGNYVESI 470


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/136 (30%), Positives = 54/136 (39%), Gaps = 13/136 (9%)

Query: 259 PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTP 318
           P  G   P PP   P   P     H P       PG   P  P  +   PPV  PP HTP
Sbjct: 694 PGFGPGVPPPPPPPPFLRPGFNPMHLP-------PGFLPPGPPPPIT--PPVSIPPPHTP 744

Query: 319 SKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 378
              +    I  + EDT   ++S+  P  P   S   G  +     +  G +A   AA ++
Sbjct: 745 PISIPNSTIAGINEDT-TKDLSIGNPI-PTVVSGARGNAESGDSVKMYG-SAVPPAAPTN 801

Query: 379 LPAVVVETFPATVNGT 394
           LP   V T P ++ GT
Sbjct: 802 LPTPPV-TQPVSLLGT 816


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/136 (30%), Positives = 54/136 (39%), Gaps = 13/136 (9%)

Query: 259 PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTP 318
           P  G   P PP   P   P     H P       PG   P  P  +   PPV  PP HTP
Sbjct: 709 PGFGPGVPPPPPPPPFLRPGFNPMHLP-------PGFLPPGPPPPIT--PPVSIPPPHTP 759

Query: 319 SKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 378
              +    I  + EDT   ++S+  P  P   S   G  +     +  G +A   AA ++
Sbjct: 760 PISIPNSTIAGINEDT-TKDLSIGNPI-PTVVSGARGNAESGDSVKMYG-SAVPPAAPTN 816

Query: 379 LPAVVVETFPATVNGT 394
           LP   V T P ++ GT
Sbjct: 817 LPTPPV-TQPVSLLGT 831


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 31/117 (26%), Positives = 42/117 (35%), Gaps = 7/117 (5%)

Query: 250  VKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGAT----LPKSPSQLR 305
            ++ +P    P      P PP   P   P +     P P    TP +     LP  P    
Sbjct: 1453 LEEKPPPTPPPAPTPQPQPPPPPPPPQPALP---SPPPLVAPTPSSPPPPPLPPPPPPAM 1509

Query: 306  KGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAG 362
              PP PPPP   P     +E      ED  +P+      ++  E + V G T   AG
Sbjct: 1510 PSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAG 1566



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 29/97 (29%), Positives = 35/97 (36%), Gaps = 11/97 (11%)

Query: 256  DNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP-- 313
            D+ P  G K  S PDG P A         P P   +      P+ P    K PP PPP  
Sbjct: 1406 DDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465

Query: 314  ---PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQP 347
               P+  P     Q  + S       P +   TPS P
Sbjct: 1466 TPQPQPPPPPPPPQPALPS------PPPLVAPTPSSP 1496



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 25/79 (31%), Positives = 29/79 (36%), Gaps = 7/79 (8%)

Query: 252  AQPSDNAPAKGNKSPSPPDGSPAATPE-----IRVNHEPEPAG--GATPGATLPKSPSQL 304
            A P    PA     P  P  +  A PE     +  N  PE      A P   +   P Q 
Sbjct: 978  AGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQA 1037

Query: 305  RKGPPVPPPPKHTPSKEVK 323
               PP PPPP   P+ E K
Sbjct: 1038 APPPPPPPPPPPAPASEPK 1056



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 29/87 (33%), Positives = 35/87 (40%), Gaps = 10/87 (11%)

Query: 244 GSNTFTVKAQ-----PSDNAPAKGNKSPSPP---DGSPAATPEIRVNHEPEPAGGATPGA 295
           GS  F V +      P  + PA G  SP        S A T    +  E    GG    A
Sbjct: 158 GSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPA 217

Query: 296 TL-PKSPSQLRKGPP-VPPPPKHTPSK 320
            L P      R GPP  PPPP+H P++
Sbjct: 218 GLGPAQTPPYRPGPPDPPPPPRHLPTQ 244



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 30/111 (27%), Positives = 36/111 (32%), Gaps = 15/111 (13%)

Query: 260  AKGNKSPSPP--DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 317
            A  N +P PP  +  P  TP      +P+P     P      SP  L    P  PPP   
Sbjct: 1442 ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPL 1501

Query: 318  PSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGE 368
            P                     S   P  PA A   A   +PAA + E  E
Sbjct: 1502 PPPPPPAMP-------------SPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 37/145 (25%), Positives = 52/145 (35%), Gaps = 20/145 (13%)

Query: 266 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQE 325
           P PP   P   P + ++H P P+  A+        P+     P  PPPP   P     Q 
Sbjct: 795 PPPP---PQLLPSV-LSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQ- 849

Query: 326 QILSLFEDTFVPEISVTTPS-QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVV 384
             L     +   E +  +P  +P E+ +  G  Q   GA EP            LP    
Sbjct: 850 --LEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEP------------LPPAPG 895

Query: 385 ETFPATVNGTVEGGSGAGRLDLPPG 409
           +T     N   +  +GA R   P G
Sbjct: 896 DTGVGPPNSEGKDPAGAYRSPSPQG 920


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/180 (26%), Positives = 61/180 (33%), Gaps = 25/180 (13%)

Query: 235  VLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG 294
            V V   ++  S    V       +PA    +P  P    AA P      EP     A P 
Sbjct: 992  VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP---PEEPTSPAAAVPT 1048

Query: 295  ATLPKSPSQLRKGPPVPPPPKH---TPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEAS 351
               P SP+     P  P  P     TP +       +   E+   P  +V TP +P    
Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---- 1104

Query: 352  EVAGGTQPAAGAQEPGETAASEAA-----SSSLPAVVVET-----FPATVNGTVEGGSGA 401
                 T PAA    P E A+  AA       + PA  V T     FPA    T E  + A
Sbjct: 1105 -----TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 16/151 (10%)

Query: 258  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKH- 316
            +PA    +P  P    AA P      EP     A P    P SP+     P  P  P   
Sbjct: 1067 SPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123

Query: 317  --TPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVA----GGTQPAAGAQEPGETA 370
              TP +       +   E+   P  +V TP + A A+           PAA    P E+A
Sbjct: 1124 VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183

Query: 371  ASEAASSSL-----PAVVVETFPATVNGTVE 396
            +  A  ++L     PA  V T PA +  T+E
Sbjct: 1184 SFAAVVATLEEPTSPAASVPT-PAAMVATLE 1213



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 13/143 (9%)

Query: 258  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL---RKGPPVPPPP 314
            +PA    +P  P    AA P      EP     A P    P SP+      + P  P P 
Sbjct: 1093 SPAAAVPTPEEPTSPAAAVP---TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA 1149

Query: 315  KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEA 374
              TP +       +   E++  P  +V TP++ A  + V       A  +EP   AAS  
Sbjct: 1150 VPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV------ATLEEPTSPAASVP 1203

Query: 375  ASSSLPAVVVE-TFPATVNGTVE 396
              +++ A + E T PA    T E
Sbjct: 1204 TPAAMVATLEEFTSPAASVPTSE 1226



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 41/151 (27%), Positives = 51/151 (33%), Gaps = 18/151 (11%)

Query: 249  TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 308
            TV A    +  A    +P  P    AA P      EP     A P    P SP+     P
Sbjct: 980  TVHAPEEPDTAAVRVSTPEEPASPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPPP 1036

Query: 309  PVPPPPKH---TPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQE 365
              P  P     TP +       +   E+   P  +V TP +P         T PAA    
Sbjct: 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---------TSPAAAVPT 1087

Query: 366  PGETAASEAASSSLPAVVVETFPATVNGTVE 396
            P E  +  AA   +P     T PA    T E
Sbjct: 1088 PEEPTSPAAA---VPTPEEPTSPAAAVPTPE 1115



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 48/197 (24%), Positives = 71/197 (36%), Gaps = 32/197 (16%)

Query: 213  SIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGS 272
            +++  EE      + + Q     + G   +  +   TV     D  P +G  +P+    +
Sbjct: 925  AVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP-EGPVTPATTVHA 983

Query: 273  PAA--TPEIRVNHEPEPAGGA----------TPGATLPKSPSQLRKGPPVPPPPKHT-PS 319
            P    T  +RV+   EPA  A          +P A +P           VPPP + T P+
Sbjct: 984  PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPA 1043

Query: 320  KEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSL 379
              V         E+   P  +V TP +P         T PAA    P E  +  AA   +
Sbjct: 1044 AAVPTP------EEPTSPAAAVPTPEEP---------TSPAAAVPTPEEPTSPAAA---V 1085

Query: 380  PAVVVETFPATVNGTVE 396
            P     T PA    T E
Sbjct: 1086 PTPEEPTSPAAAVPTPE 1102


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 38/154 (24%), Positives = 62/154 (40%), Gaps = 39/154 (25%)

Query: 345  SQPAEASEVAGGTQPAAGAQEPGE--------------TAASEAASSSLP---AVVVETF 387
            S+ A A  ++GG + +  ++ P                TA   A ++ LP   +  V T 
Sbjct: 6538 SRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQ 6597

Query: 388  PATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQ 447
              TV+      S AG++          +A +DY A D DE+  K GD ++     N +  
Sbjct: 6598 QTTVSSIPSHPSTAGKI---------FRAMYDYMAADADEVSFKDGDAII-----NVQAI 6643

Query: 448  DEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 481
            DEGW+ G  +             G+ P N+ E +
Sbjct: 6644 DEGWMYGTVQRTGR--------TGMLPANYVEAI 6669


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 40/190 (21%), Positives = 69/190 (36%), Gaps = 3/190 (1%)

Query: 195 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 253
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL--PKSPSQLRKGPPVP 311
           P+ +A      S S P  + AA P      +  P+  A P  T   P  P+     P   
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 312 PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAA 371
            PP+ T +         +    +  PE +   P+  A   + +  + P      P   +A
Sbjct: 230 APPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSA 289

Query: 372 SEAASSSLPA 381
           +  A  S PA
Sbjct: 290 TTPAPPSSPA 299



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 32/140 (22%), Positives = 46/140 (32%), Gaps = 19/140 (13%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDG------SPAATPEIRV--------NHEPEPAGGATPG 294
           T  A PS +AP +   +P  P        S +A PE             +P  A      
Sbjct: 221 TTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPET 280

Query: 295 ATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT--PSQPAEASE 352
              P +PS     PP  P P+ T +  +      +    T  P+ S T+  P+     S 
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTP---NSSPTTLAPDTSETSAAPTHQTTTSV 337

Query: 353 VAGGTQPAAGAQEPGETAAS 372
               T        PG+   S
Sbjct: 338 TTQTTTTKQPTSAPGQNKIS 357


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 18/124 (14%)

Query: 258 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 317
           A A G    +P +G+P A P      EP PAG A PG   P+ P       P+ P     
Sbjct: 68  AGAAGAGPAAPAEGAPGAAP------EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 318 PSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA-AGAQEPGETAASEAAS 376
           P+ +++             PE S  + +    A+ VA G +PA AG  +P   AA  A +
Sbjct: 122 PAAKLRPP-----------PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170

Query: 377 SSLP 380
              P
Sbjct: 171 GPGP 174



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 44/161 (27%), Positives = 58/161 (36%), Gaps = 38/161 (23%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG-ATLPKSPSQLRKGP---- 308
           P   APA   + P  P G P A P +     P PA     G A    +P+    GP    
Sbjct: 272 PPPPAPATLARPPGHPAGPPTAAPAV-----PPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326

Query: 309 --PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEP 366
             P P      P+  VK E                 +P +  +A+  A  T  A+G   P
Sbjct: 327 GQPGPGAAAAAPAPGVKAE-----------------SPKRVVQAAPPAAQTLAASG---P 366

Query: 367 GETAASEAASSSL------PAVVVETFPATVNGTVEGGSGA 401
             TAAS     ++      PA V    P T  G  +G +GA
Sbjct: 367 ASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGA 407



 Score = 36.2 bits (82), Expect = 0.068
 Identities = 41/156 (26%), Positives = 52/156 (33%), Gaps = 35/156 (22%)

Query: 256 DNAPAKGNKSPSPP-DGSPAATPE-IRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
           +N PA     P P   G+   TP  +     P PA  + P A  P +P+     PP PPP
Sbjct: 219 NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA---AAPPPPPP 275

Query: 314 PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASE 373
                                  P      P  PA     A    P A AQ  G   A+ 
Sbjct: 276 ----------------------APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAP 313

Query: 374 AASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 409
           A + +         PA V+G  + G GA      PG
Sbjct: 314 APAPAAGG------PAGVSG--QPGPGAAAAAPAPG 341



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 34/161 (21%), Positives = 53/161 (32%), Gaps = 1/161 (0%)

Query: 252 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVP 311
           A P   A   G  + + P  +PAA     V+ +P P   A   A   K+ S  R     P
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP 355

Query: 312 PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAA 371
           P  +   +          +   T    +       P       G  + AAGA     +  
Sbjct: 356 PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRT 415

Query: 372 SEAASSSLPAVVVETFPA-TVNGTVEGGSGAGRLDLPPGFM 411
             A +S + A +  T  A  +    +  +      LPPG +
Sbjct: 416 PTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMV 456


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 40/190 (21%), Positives = 69/190 (36%), Gaps = 3/190 (1%)

Query: 195 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 253
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL--PKSPSQLRKGPPVP 311
           P+ +A      S S P  + AA P      +  P+  A P  T   P  P+     P   
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 312 PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAA 371
            PP+ T +         +    +  PE +   P+  A   + +  + P      P   +A
Sbjct: 230 APPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSA 289

Query: 372 SEAASSSLPA 381
           +  A  S PA
Sbjct: 290 TTPAPPSSPA 299



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 32/140 (22%), Positives = 46/140 (32%), Gaps = 19/140 (13%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDG------SPAATPEIRV--------NHEPEPAGGATPG 294
           T  A PS +AP +   +P  P        S +A PE             +P  A      
Sbjct: 221 TTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPET 280

Query: 295 ATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT--PSQPAEASE 352
              P +PS     PP  P P+ T +  +      +    T  P+ S T+  P+     S 
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTP---NSSPTTLAPDTSETSAAPTHQTTTSV 337

Query: 353 VAGGTQPAAGAQEPGETAAS 372
               T        PG+   S
Sbjct: 338 TTQTTTTKQPTSAPGQNKIS 357


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 40/190 (21%), Positives = 69/190 (36%), Gaps = 3/190 (1%)

Query: 195 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 253
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL--PKSPSQLRKGPPVP 311
           P+ +A      S S P  + AA P      +  P+  A P  T   P  P+     P   
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 312 PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAA 371
            PP+ T +         +    +  PE +   P+  A   + +  + P      P   +A
Sbjct: 230 APPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSA 289

Query: 372 SEAASSSLPA 381
           +  A  S PA
Sbjct: 290 TTPAPPSSPA 299



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 32/140 (22%), Positives = 46/140 (32%), Gaps = 19/140 (13%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDG------SPAATPEIRV--------NHEPEPAGGATPG 294
           T  A PS +AP +   +P  P        S +A PE             +P  A      
Sbjct: 221 TTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPET 280

Query: 295 ATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT--PSQPAEASE 352
              P +PS     PP  P P+ T +  +      +    T  P+ S T+  P+     S 
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTP---NSSPTTLAPDTSETSAAPTHQTTTSV 337

Query: 353 VAGGTQPAAGAQEPGETAAS 372
               T        PG+   S
Sbjct: 338 TTQTTTTKQPTSAPGQNKIS 357


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,232,297
Number of Sequences: 37866
Number of extensions: 1211471
Number of successful extensions: 12006
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 1012
Number of HSP's that attempted gapping in prelim test: 8365
Number of HSP's gapped (non-prelim): 3636
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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