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Search of human proteins with 214830928
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|214830928 coiled-coil domain containing 113 isoform 2 [Homo
sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|214830928 coiled-coil domain containing 113 isoform 2 [Homo s... 620 e-178
gi|19923432 coiled-coil domain containing 113 isoform 1 [Homo sa... 573 e-164
gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 75 1e-13
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 59 6e-09
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 59 6e-09
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 57 2e-08
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 54 1e-07
gi|119943086 Tax1 (human T-cell leukemia virus type I) binding p... 53 3e-07
gi|21361682 Tax1 (human T-cell leukemia virus type I) binding pr... 53 3e-07
gi|55770834 centromere protein F [Homo sapiens] 52 9e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 1e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 51 1e-06
gi|153791839 sodium channel associated protein 1 [Homo sapiens] 51 2e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 2e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 6e-06
gi|45439370 TAO kinase 1 [Homo sapiens] 49 6e-06
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 49 6e-06
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 48 1e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 1e-05
gi|4504063 golgin 97 [Homo sapiens] 48 1e-05
gi|50083279 centrosome protein 4 [Homo sapiens] 48 1e-05
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 48 1e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 47 2e-05
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 47 2e-05
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 47 2e-05
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 47 2e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 2e-05
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 47 2e-05
gi|4503593 epidermal growth factor receptor pathway substrate 15... 47 3e-05
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 47 3e-05
>gi|214830928 coiled-coil domain containing 113 isoform 2 [Homo
sapiens]
Length = 323
Score = 620 bits (1598), Expect = e-178
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 60
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
Sbjct: 1 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 60
Query: 61 PPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKY 120
PPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKY
Sbjct: 61 PPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKY 120
Query: 121 IEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE 180
IEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE
Sbjct: 121 IEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE 180
Query: 181 TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQ 240
TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQ
Sbjct: 181 TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQ 240
Query: 241 VEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKG 300
VEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKG
Sbjct: 241 VEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKG 300
Query: 301 HRKAWNRMKITNEQLQADYLAGK 323
HRKAWNRMKITNEQLQADYLAGK
Sbjct: 301 HRKAWNRMKITNEQLQADYLAGK 323
>gi|19923432 coiled-coil domain containing 113 isoform 1 [Homo
sapiens]
Length = 377
Score = 573 bits (1476), Expect = e-164
Identities = 313/377 (83%), Positives = 317/377 (84%), Gaps = 54/377 (14%)
Query: 1 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 60
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
Sbjct: 1 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 60
Query: 61 PPR-------------------------------------LSEIKISAAD---------- 73
PPR L ++ AD
Sbjct: 61 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA 120
Query: 74 -------YAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR 126
+ +AIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
Sbjct: 121 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR 180
Query: 127 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN 186
RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
Sbjct: 181 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN 240
Query: 187 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA 246
QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
Sbjct: 241 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA 300
Query: 247 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN 306
KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN
Sbjct: 301 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN 360
Query: 307 RMKITNEQLQADYLAGK 323
RMKITNEQLQADYLAGK
Sbjct: 361 RMKITNEQLQADYLAGK 377
>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
Length = 555
Score = 74.7 bits (182), Expect = 1e-13
Identities = 67/254 (26%), Positives = 121/254 (47%), Gaps = 29/254 (11%)
Query: 64 LSEIKISAADYAQAIIEE-------AEIRWSEVSREVHEFE----KDILKAIS--KKKGS 110
L E+K AD Q +E + + + V +E F+ + +++A+ + +G
Sbjct: 291 LEELKKQQADDLQWYHQELGQLKRQCQEKLTRVEKEWRRFQALKKQVVMQAMGSCRMRGG 350
Query: 111 ILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQ 170
A + ++ I+ + +++ +RL+N+ LK ++R +E++++ L +DF+Q
Sbjct: 351 RQAALREVEQIQALEDKKEKEMSAVRLENIQLKQSLVHFETRMRTQEDLTQGLLLIDFEQ 410
Query: 171 LKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKEL 230
LKIEN F E IE RN+EL +L+ N++QV+ K KLH +D E +K
Sbjct: 411 LKIENQTFNEKIEERNEELLKLRSKVTNSVQVITHVKEKLH-------FMDMENACKKTQ 463
Query: 231 LEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSI---RMW 287
L +IE + + K + + LR R Q + + L DLE+ + +
Sbjct: 464 LAEIEAQAALGRDILTKTKQAREGLRTD--NIRLNQKCGLLGKDSLLRDLEEKVDKTELL 521
Query: 288 ERKVEIAEMSLKGH 301
R++E SLK H
Sbjct: 522 HRRLE----SLKRH 531
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 58.9 bits (141), Expect = 6e-09
Identities = 72/303 (23%), Positives = 139/303 (45%), Gaps = 29/303 (9%)
Query: 7 ESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSE 66
ES+ S + S++E Q+ +EL + + E+ + + + + +++
Sbjct: 594 ESIKETSSKLSKIEFEKRQI---KKELEHYKEKGERAEELENELHHLEKENELLQKKITN 650
Query: 67 IKISAADYAQAIIEEAEIRWSEVSREVHEFEKDI---------LKAISKKKGSILATQKV 117
+KI+ IE E SE+ RE + +K + L+++ K+ +
Sbjct: 651 LKITCEK-----IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 118 MKYIEDMNRRRDNMKEKLRLKNVSL---KVQRKKMLLQLRQKEEVSEALHDVDFQQLKIE 174
++ + + +L+L+N L K Q KK L L+ + +E L +V +Q L IE
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL-EVSYQGLDIE 764
Query: 175 NAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKI 234
N + +T+E N+++ QL+ + LQ L L K +E K + ++ + +
Sbjct: 765 NQRLQKTLENSNKKIQQLE----SELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Query: 235 EKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIA 294
E+ET Q+E+D+ + E NKRLR+Q AE + T + +LEK + +++ I
Sbjct: 821 EQETSQLEKDKKQLEKENKRLRQQ-AEIKD---TTLEENNVKIGNLEKENKTLSKEIGIY 876
Query: 295 EMS 297
+ S
Sbjct: 877 KES 879
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/329 (17%), Positives = 140/329 (42%), Gaps = 52/329 (15%)
Query: 3 DDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPP 62
++++E +L E ++E+ + + L N L ++ Y +L+ ++
Sbjct: 268 EEKTEQLLDCKQELEQMEIEL-------KRLQQENMNLLSDARSARMYRDELDALREKAV 320
Query: 63 RLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIE 122
R+ +++ + Y + + + E + V E+ E + +L+ + + + T+ +
Sbjct: 321 RVDKLESEVSRYKERL-HDIEFYKARVE-ELKEDNQVLLETKTMLEDQLEGTRARSDKLH 378
Query: 123 DMNRRRDNMKEKLRLKNVSLKVQRKK--------MLLQLRQKEEVSEALH---------- 164
++ + +K KL + + RKK M L++ QK+ + E+LH
Sbjct: 379 ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISR 438
Query: 165 ----------DVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAM 214
+ + ++ +++ L+ +E NQ LT+ T+ + SK+
Sbjct: 439 TSELSEAPQKSLGHEVNELTSSRLLK-LEMENQSLTKTVEELRTTVDSVEGNASKI---- 493
Query: 215 EIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREK 274
L ++KE + +E +E E +Q ++ + ++K L K+ A+ + + +RE
Sbjct: 494 ---LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLE--KTIETLRE- 547
Query: 275 ILNADLEKSIRMWERKVEIAEMSLKGHRK 303
+ E+ I++ E++ E ++ R+
Sbjct: 548 ----NSERQIKILEQENEHLNQTVSSLRQ 572
Score = 37.4 bits (85), Expect = 0.018
Identities = 53/306 (17%), Positives = 127/306 (41%), Gaps = 38/306 (12%)
Query: 30 VEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEV 89
+E+L N +L+ ET EK +LE ++R + +EIK + + I E +
Sbjct: 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL 869
Query: 90 SREVHEFEKDILKAIS-KKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKK 148
S+E+ +++ ++ +K+ L + + + R D + EKL+ + ++ +++
Sbjct: 870 SKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Query: 149 MLLQL--RQKEEVSEALHDVDFQQLKIENAQFLET----IEARNQELTQLKLSSGNTLQV 202
L+ KE + D + K+ ++ T +E + +++ L+ +
Sbjct: 930 HELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNY 989
Query: 203 LNAYKSKLHKAMEIYLNL----DKEILLR--------------------KELLEKIEKET 238
+ +L + Y L D+E +++ +ELL K++
Sbjct: 990 NQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELL-KVKDRL 1048
Query: 239 LQVEEDRAKAEAVNKRLRKQLAEFRA------PQVMTYVREKILNADLEKSIRMWERKVE 292
++VE + A +A + L+ QL + Q++ R+ + + +++ K++
Sbjct: 1049 IEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1108
Query: 293 IAEMSL 298
+ +L
Sbjct: 1109 VENSTL 1114
Score = 33.9 bits (76), Expect = 0.20
Identities = 45/203 (22%), Positives = 91/203 (44%), Gaps = 21/203 (10%)
Query: 32 ELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSR 91
+L NS L +++ A+L + +E I + +++ + I+ E
Sbjct: 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSL-IKDHEKLE 1164
Query: 92 EVHEFEKDILKAISKKKGSILATQKVMKY----IEDMNRRRDNMKEKLRLKNVS--LKVQ 145
+HE + +++ K G++ + K ++ +ED R +K+K +L+++ LKV+
Sbjct: 1165 LLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED--RYNQLLKQKGQLEDLEKMLKVE 1222
Query: 146 RKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNA 205
++KMLL+ + E V+ ++++L EN + T +E L+ N +LN
Sbjct: 1223 QEKMLLENKNHETVA-----AEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNN 1277
Query: 206 YK-------SKLHKAMEIYLNLD 221
K ++ K E Y LD
Sbjct: 1278 SKLEQTRLEAEFSKLKEQYQQLD 1300
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 58.9 bits (141), Expect = 6e-09
Identities = 72/303 (23%), Positives = 139/303 (45%), Gaps = 29/303 (9%)
Query: 7 ESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSE 66
ES+ S + S++E Q+ +EL + + E+ + + + + +++
Sbjct: 594 ESIKETSSKLSKIEFEKRQI---KKELEHYKEKGERAEELENELHHLEKENELLQKKITN 650
Query: 67 IKISAADYAQAIIEEAEIRWSEVSREVHEFEKDI---------LKAISKKKGSILATQKV 117
+KI+ IE E SE+ RE + +K + L+++ K+ +
Sbjct: 651 LKITCEK-----IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 118 MKYIEDMNRRRDNMKEKLRLKNVSL---KVQRKKMLLQLRQKEEVSEALHDVDFQQLKIE 174
++ + + +L+L+N L K Q KK L L+ + +E L +V +Q L IE
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL-EVSYQGLDIE 764
Query: 175 NAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKI 234
N + +T+E N+++ QL+ + LQ L L K +E K + ++ + +
Sbjct: 765 NQRLQKTLENSNKKIQQLE----SELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Query: 235 EKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIA 294
E+ET Q+E+D+ + E NKRLR+Q AE + T + +LEK + +++ I
Sbjct: 821 EQETSQLEKDKKQLEKENKRLRQQ-AEIKD---TTLEENNVKIGNLEKENKTLSKEIGIY 876
Query: 295 EMS 297
+ S
Sbjct: 877 KES 879
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/329 (17%), Positives = 140/329 (42%), Gaps = 52/329 (15%)
Query: 3 DDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPP 62
++++E +L E ++E+ + + L N L ++ Y +L+ ++
Sbjct: 268 EEKTEQLLDCKQELEQMEIEL-------KRLQQENMNLLSDARSARMYRDELDALREKAV 320
Query: 63 RLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIE 122
R+ +++ + Y + + + E + V E+ E + +L+ + + + T+ +
Sbjct: 321 RVDKLESEVSRYKERL-HDIEFYKARVE-ELKEDNQVLLETKTMLEDQLEGTRARSDKLH 378
Query: 123 DMNRRRDNMKEKLRLKNVSLKVQRKK--------MLLQLRQKEEVSEALH---------- 164
++ + +K KL + + RKK M L++ QK+ + E+LH
Sbjct: 379 ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISR 438
Query: 165 ----------DVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAM 214
+ + ++ +++ L+ +E NQ LT+ T+ + SK+
Sbjct: 439 TSELSEAPQKSLGHEVNELTSSRLLK-LEMENQSLTKTVEELRTTVDSVEGNASKI---- 493
Query: 215 EIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREK 274
L ++KE + +E +E E +Q ++ + ++K L K+ A+ + + +RE
Sbjct: 494 ---LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLE--KTIETLRE- 547
Query: 275 ILNADLEKSIRMWERKVEIAEMSLKGHRK 303
+ E+ I++ E++ E ++ R+
Sbjct: 548 ----NSERQIKILEQENEHLNQTVSSLRQ 572
Score = 37.0 bits (84), Expect = 0.024
Identities = 55/305 (18%), Positives = 126/305 (41%), Gaps = 37/305 (12%)
Query: 30 VEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEV 89
+E+L N +L+ ET EK +LE ++R + +EIK + + I E +
Sbjct: 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL 869
Query: 90 SREVHEFEKDILKAIS-KKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQR-- 146
S+E+ +++ ++ +K+ L + + + R D + EKL+ + ++ +++
Sbjct: 870 SKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Query: 147 ---------KKMLLQLRQKEE-----VSEALHDVDFQQLKIENAQFLETIEARNQELT-- 190
K+ LL Q + + L + L+I+ + + +EAR +E T
Sbjct: 930 HELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEK-IAALEARLEESTNY 988
Query: 191 --QLKLSSGNTLQVLNAYKSKLHKAMEIYLN---------LDKEILLRKELLEKIEKETL 239
QL+ + A K + + + + ++E L K++ +
Sbjct: 989 NQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLI 1048
Query: 240 QVEEDRAKAEAVNKRLRKQLAEFRA------PQVMTYVREKILNADLEKSIRMWERKVEI 293
+VE + A +A + L+ QL + Q++ R+ + + +++ K+++
Sbjct: 1049 EVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 1108
Query: 294 AEMSL 298
+L
Sbjct: 1109 ENSTL 1113
Score = 33.9 bits (76), Expect = 0.20
Identities = 45/203 (22%), Positives = 91/203 (44%), Gaps = 21/203 (10%)
Query: 32 ELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSR 91
+L NS L +++ A+L + +E I + +++ + I+ E
Sbjct: 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSL-IKDHEKLE 1163
Query: 92 EVHEFEKDILKAISKKKGSILATQKVMKY----IEDMNRRRDNMKEKLRLKNVS--LKVQ 145
+HE + +++ K G++ + K ++ +ED R +K+K +L+++ LKV+
Sbjct: 1164 LLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED--RYNQLLKQKGQLEDLEKMLKVE 1221
Query: 146 RKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNA 205
++KMLL+ + E V+ ++++L EN + T +E L+ N +LN
Sbjct: 1222 QEKMLLENKNHETVA-----AEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNN 1276
Query: 206 YK-------SKLHKAMEIYLNLD 221
K ++ K E Y LD
Sbjct: 1277 SKLEQTRLEAEFSKLKEQYQQLD 1299
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 57.4 bits (137), Expect = 2e-08
Identities = 64/310 (20%), Positives = 143/310 (46%), Gaps = 30/310 (9%)
Query: 36 VNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIE-EAEIRWSEVSRE-V 93
++S+ K + E+ + +DQ + ++ A Y ++E E + +V +E
Sbjct: 981 LDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERA 1040
Query: 94 HEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS-LKVQRKKMLL- 151
+ FE I + + S L + + ED+ R + ++ +L V L+VQR K ++
Sbjct: 1041 NNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVD 1100
Query: 152 ------QLRQKEEVSEALHDV-DFQQLKIE----------NAQFLETIEARNQELTQLKL 194
+L++++++ E V + ++L+++ Q LE ++ Q+ T + +
Sbjct: 1101 KELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNM 1160
Query: 195 SSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETL-------QVEEDRAK 247
+ +++ KL +L++EI ++K+ E +++E Q EE K
Sbjct: 1161 EIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTK 1220
Query: 248 AEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWE-RKVEIAEMSLKGHRKAWN 306
+ + + +K+LA+ + + + + L +LE S + E K+++AE++ + H K
Sbjct: 1221 IKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKH-KIHE 1279
Query: 307 RMKITNEQLQ 316
+K + EQ Q
Sbjct: 1280 HLKTSAEQHQ 1289
Score = 41.2 bits (95), Expect = 0.001
Identities = 62/328 (18%), Positives = 132/328 (40%), Gaps = 36/328 (10%)
Query: 1 MTDDESESVLSDSH------EGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKL 54
+ D E E VL E L+ ++++ E+ N L + E + +K
Sbjct: 833 LRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKS 892
Query: 55 EPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILAT 114
E +++ + I + + ++E+ E+R + E+ + + K+ S K + +
Sbjct: 893 EIHNEK----EKCFIKEHENLKPLLEQKELR--DRRAELILLKDSLAKSPSVKNDPLSSV 946
Query: 115 QKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIE 174
+++ + IE++ + +EK+ K L+ ++ K+E+ + + E
Sbjct: 947 KELEEKIENLEKECKEKEEKIN----------KIKLVAVKAKKELDSS---------RKE 987
Query: 175 NAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKI 234
E +E+ E QL S + +Q +YK+ L + + LD E +I
Sbjct: 988 TQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRI 1047
Query: 235 EKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEI- 293
E T Q+ + E +N LA Q + E + +++++ M ++++E
Sbjct: 1048 EDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLE-VQILEVQRAKAMVDKELEAE 1106
Query: 294 ---AEMSLKGHRKAWNRMKITNEQLQAD 318
E +K H N ++ QLQ +
Sbjct: 1107 KLQKEQKIKEHATTVNELEELQVQLQKE 1134
Score = 36.6 bits (83), Expect = 0.031
Identities = 44/221 (19%), Positives = 96/221 (43%), Gaps = 20/221 (9%)
Query: 1 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 60
M D E E+ E + E + + V EL + L+ E + +K +LE +
Sbjct: 1098 MVDKELEA------EKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKD 1151
Query: 61 PPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSIL-----ATQ 115
+ + + + ADY + +++E + + + ++ + E++I I K+K L + Q
Sbjct: 1152 AQQTTLMNMEIADY-ERLMKELNQKLTNKNNKIEDLEQEI--KIQKQKQETLQEEITSLQ 1208
Query: 116 KVMKYIEDMNRRRDNMKEKLRLKNVSLK-VQRKKMLLQLRQKEEVSEALHDVDFQQLKIE 174
++ E+ N + + K + + K + ++LQ K E+ + QQ+++
Sbjct: 1209 SSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGEL-----EASQQQVEVY 1263
Query: 175 NAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAME 215
Q E +++ LK S+ + L+AY+ ++ E
Sbjct: 1264 KIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQE 1304
Score = 33.1 bits (74), Expect = 0.34
Identities = 35/181 (19%), Positives = 82/181 (45%), Gaps = 32/181 (17%)
Query: 121 IEDMNRRRDNMKEKLR-----LKNVSLKVQRK-KMLLQLRQKEE---------------- 158
I + +D+ KL+ + N K +R+ +++L+L +K E
Sbjct: 589 INSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNEL 648
Query: 159 ---VSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSS-GNTLQVLNAYKSKLHKAM 214
+ E L + D K+E + + ++E+ ++ S L++ K +L + +
Sbjct: 649 TGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDL 708
Query: 215 EIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE--FRAPQVMTYVR 272
E++L+ ++++L++ + + +K L VEE + +NK L + + F Q+ +++
Sbjct: 709 EVFLSQKEDVILKEHITQLEKKLQLMVEEQ----DNLNKLLENEQVQKLFVKTQLYGFLK 764
Query: 273 E 273
E
Sbjct: 765 E 765
Score = 32.3 bits (72), Expect = 0.58
Identities = 63/344 (18%), Positives = 137/344 (39%), Gaps = 53/344 (15%)
Query: 14 HEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKL---------EPRDQRPPRL 64
HE +LE + +L EE V LK+E K + ++Q +
Sbjct: 378 HEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEI 437
Query: 65 SEI-----------KISAADYAQAIIEEAEIRWSEVSREVHEFE--KDILKAISKKKGSI 111
SE+ K++ Q + E+ E E + +E ++I++ + + G
Sbjct: 438 SELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGE- 496
Query: 112 LATQKVMKYIEDMNRRR----DNMKEKLR---------LKNVS-LKVQRKKMLLQLRQKE 157
+ K+ + E M +++ +++KLR L+ V+ L+ + +K+L Q
Sbjct: 497 -SAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVP 555
Query: 158 EVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIY 217
E+ + + L+ +N +L ++ R+ L +L+ + + + + +KL + E
Sbjct: 556 ELENTI-----KNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEM 610
Query: 218 LNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILN 277
N K+ + L+ ++ K+ Q + N L +++ E T + +
Sbjct: 611 DNFHKKCEREERLILELGKKVEQTIQ-------YNSELEQKVNELTGGLEETLKEKDQND 663
Query: 278 ADLEK---SIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQAD 318
LEK +++ E+ +K + N++ +QL D
Sbjct: 664 QKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRD 707
Score = 28.9 bits (63), Expect = 6.5
Identities = 54/248 (21%), Positives = 106/248 (42%), Gaps = 20/248 (8%)
Query: 18 ELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQA 77
E E + +L L E L V +E + +KY +LE + ++
Sbjct: 265 EHEAEINKLNELKENL--VKQCEASEKNIQKKYECELENLRKATSNANQDN----QICSI 318
Query: 78 IIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRD----NMKE 133
+++E V+ +V E D LK + + SIL + + Y+ ++ + + ++K+
Sbjct: 319 LLQENTFVEQVVNEKVKHLE-DTLKELESQH-SILKDE--VTYMNNLKLKLEMDAQHIKD 374
Query: 134 KLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLK 193
+ + L+ + ++LL ++ V E L +L N QF T+E N+E+ LK
Sbjct: 375 EFFHEREDLEFKINELLLAKEEQGCVIEKLKS----ELAGLNKQFCYTVEQHNREVQSLK 430
Query: 194 LSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNK 253
+ LN ++ L + + L L EI KE E +++E + + + +
Sbjct: 431 EQHQKEISELN--ETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIME 488
Query: 254 RLRKQLAE 261
L+ +L E
Sbjct: 489 ILQTELGE 496
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 54.3 bits (129), Expect = 1e-07
Identities = 63/294 (21%), Positives = 127/294 (43%), Gaps = 28/294 (9%)
Query: 31 EELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVS 90
EE++ L +E + A+ + Q R E A Q +E + R +E S
Sbjct: 156 EEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQ---QEIQQRQNEAS 212
Query: 91 REVHEFEK------DILKAISKKKGSILATQK-VMKYIEDMNRRRDNMKEKLRLKNVSLK 143
RE + EK I + ++ I A Q+ V K E++ + +KE+ L + K
Sbjct: 213 REFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAK 272
Query: 144 VQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVL 203
+ + + ++E + H + +QL EN Q ++A+ +E+ Q++L G L
Sbjct: 273 ELEQFQMRNAKLQQENEQ--HSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGK----L 326
Query: 204 NAYKSKLHKAMEIYLNLDKEILLRKELLE-KIEKETLQVEEDRAKAEAVNKRLRKQLAEF 262
N + ++HK + + E+ KE L+ +I +VE + +AE K + + L E
Sbjct: 327 NKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRE- 385
Query: 263 RAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQ 316
ILN ++ K++ +++ ++ ++ + R ++ ++ Q
Sbjct: 386 ----------RDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQ 429
Score = 30.4 bits (67), Expect = 2.2
Identities = 32/151 (21%), Positives = 67/151 (44%), Gaps = 15/151 (9%)
Query: 114 TQKVMKYIEDMNRRRDNM---KEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQ 170
TQKV+ +ED+ R + ++K+ + LK Q+ L + L+ + +
Sbjct: 453 TQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQN-----LYEAVRSDRNLYSKNLVE 507
Query: 171 LKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKEL 230
+ E ++ ++ +LK + ++A +S L K ++KE K
Sbjct: 508 AQDEITDMKRKLKIMIHQVDELK-------EDISAKESALVKLHLEQQRIEKEKETLKAE 560
Query: 231 LEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 261
L+K+ ++ L+ + K EA ++L + +AE
Sbjct: 561 LQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Score = 30.0 bits (66), Expect = 2.9
Identities = 53/243 (21%), Positives = 104/243 (42%), Gaps = 31/243 (12%)
Query: 43 ETEMFE--KYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSRE----VHEF 96
ET++F+ K A+ E + ++ L E S + + EA+ +++ R+ +H+
Sbjct: 467 ETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQV 526
Query: 97 EKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLK-------VQRKKM 149
+ ++ + IS K+ +++ + IE +KLR + + K + +K+
Sbjct: 527 D-ELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKL 585
Query: 150 LL--------QLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ 201
L +LRQK+E+ + + + D I +Q + RN EL L
Sbjct: 586 LRIIAEADGERLRQKKELDQVISERD-----ILGSQLVR----RNDELALLYEKIKIQQS 636
Query: 202 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 261
VLN +S+ ++ +E L EI + + + VEE R + + + L K+
Sbjct: 637 VLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRELLKERTR 696
Query: 262 FRA 264
RA
Sbjct: 697 CRA 699
>gi|119943086 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform b [Homo sapiens]
Length = 747
Score = 53.1 bits (126), Expect = 3e-07
Identities = 79/335 (23%), Positives = 152/335 (45%), Gaps = 49/335 (14%)
Query: 1 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLE----P 56
M D+ + +L + + LEL + + EEL + + L+ ET + ++E
Sbjct: 132 MEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVGRMERELNH 191
Query: 57 RDQRPPRLSEIKISAADYAQAI---IEEAEIRWSEVSREVHEFEKDILKAISKKKGSILA 113
+R +L + + Q++ EE + R+S+ + + H+ E+DI+ K A
Sbjct: 192 EKERCDQLQAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIVSVTHK------A 245
Query: 114 TQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSE-ALHDVDFQQLK 172
+K D++K+KL+ K Q ++ L+ + K E E L+ V + +
Sbjct: 246 IEK--------ETELDSLKDKLK------KAQHEREQLECQLKTEKDEKELYKVHLKNTE 291
Query: 173 IENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLE 232
IEN + + E+ LK GN V+ +K ++ + +++ L +KE L R LL
Sbjct: 292 IENTKLM-------SEVQTLKNLDGNKESVITHFKEEIGR-LQLCL-AEKENLQRTFLLT 342
Query: 233 KIEKE-TLQVEEDRAKAEAVNKRLRKQLAEFRAPQV--MTYVREKILNADLEKSIRMWER 289
KE T ++E KAE + R+++ F A ++ VR++ + ADL + R+
Sbjct: 343 TSSKEDTCFLKEQLRKAEEQVQATRQEVV-FLAKELSDAVNVRDRTM-ADLH-TARLENE 399
Query: 290 KVE------IAEMSLKGHRKAWNRMKITNEQLQAD 318
KV+ +AE+ L +K ++ +L+ +
Sbjct: 400 KVKKQLADAVAELKLNAMKKDQDKTDTLEHELRRE 434
>gi|21361682 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform a [Homo sapiens]
Length = 789
Score = 53.1 bits (126), Expect = 3e-07
Identities = 79/335 (23%), Positives = 152/335 (45%), Gaps = 49/335 (14%)
Query: 1 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLE----P 56
M D+ + +L + + LEL + + EEL + + L+ ET + ++E
Sbjct: 132 MEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVGRMERELNH 191
Query: 57 RDQRPPRLSEIKISAADYAQAI---IEEAEIRWSEVSREVHEFEKDILKAISKKKGSILA 113
+R +L + + Q++ EE + R+S+ + + H+ E+DI+ K A
Sbjct: 192 EKERCDQLQAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIVSVTHK------A 245
Query: 114 TQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSE-ALHDVDFQQLK 172
+K D++K+KL+ K Q ++ L+ + K E E L+ V + +
Sbjct: 246 IEK--------ETELDSLKDKLK------KAQHEREQLECQLKTEKDEKELYKVHLKNTE 291
Query: 173 IENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLE 232
IEN + + E+ LK GN V+ +K ++ + +++ L +KE L R LL
Sbjct: 292 IENTKLM-------SEVQTLKNLDGNKESVITHFKEEIGR-LQLCL-AEKENLQRTFLLT 342
Query: 233 KIEKE-TLQVEEDRAKAEAVNKRLRKQLAEFRAPQV--MTYVREKILNADLEKSIRMWER 289
KE T ++E KAE + R+++ F A ++ VR++ + ADL + R+
Sbjct: 343 TSSKEDTCFLKEQLRKAEEQVQATRQEVV-FLAKELSDAVNVRDRTM-ADLH-TARLENE 399
Query: 290 KVE------IAEMSLKGHRKAWNRMKITNEQLQAD 318
KV+ +AE+ L +K ++ +L+ +
Sbjct: 400 KVKKQLADAVAELKLNAMKKDQDKTDTLEHELRRE 434
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 51.6 bits (122), Expect = 9e-07
Identities = 59/270 (21%), Positives = 120/270 (44%), Gaps = 19/270 (7%)
Query: 1 MTDDESESVLSDSHEG-SELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQ 59
M+++ E V+ D+ +E+E Q+ + L L T E +++ +
Sbjct: 2165 MSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQG 2224
Query: 60 RPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMK 119
+ L ++ S + E+AEI+ E S+ E ++ LK +++ ++ Q++MK
Sbjct: 2225 QLSELDKLLSSFKSLLEEK-EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2283
Query: 120 Y--------IEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQL 171
IE+ ++ R+++ EKLR + L+ KK L L+Q + E+ H D +
Sbjct: 2284 ATEQSLDPPIEEEHQLRNSI-EKLRAR---LEADEKKQLCVLQQ---LKESEHHADLLKG 2336
Query: 172 KIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELL 231
++EN + I NQE L + N+ + K+K+ + L+ +++ +
Sbjct: 2337 RVENLERELEIARTNQE--HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEK 2394
Query: 232 EKIEKETLQVEEDRAKAEAVNKRLRKQLAE 261
E + E + +E ++ E +N L E
Sbjct: 2395 ENLTNELQKEQERISELEIINSSFENILQE 2424
Score = 46.2 bits (108), Expect = 4e-05
Identities = 58/254 (22%), Positives = 115/254 (45%), Gaps = 18/254 (7%)
Query: 9 VLSDSHEG--SELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSE 66
VL S++ +ELEL + VE+ VN ETE+ + + + + LS
Sbjct: 2585 VLQSSYKNLENELELTKMDKMSFVEK---VNKMTAKETELQREMHEMAQKTAELQEELSG 2641
Query: 67 IKISAADYAQAIIEE---AEIRWSEVSREVHEFEKDI---LKAISKKKGSILATQKVMKY 120
K A Q ++EE ++ + E++ E E +K + K +K+G + +++ +Y
Sbjct: 2642 EKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKV--REEIAEY 2699
Query: 121 IEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE 180
++ + L N +V+ + +L KEE + ++ LK +
Sbjct: 2700 QLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSS-QKLEIDLLKSSKEELNN 2758
Query: 181 TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKA---MEIYLNLDKEILLRKELLEKIEKE 237
+++A Q L +LK + + L+ +N K + +A M++ + K++ KE+L+K E
Sbjct: 2759 SLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQK-ELS 2817
Query: 238 TLQVEEDRAKAEAV 251
LQ +++ K V
Sbjct: 2818 QLQAAQEKQKTGTV 2831
Score = 39.7 bits (91), Expect = 0.004
Identities = 60/275 (21%), Positives = 122/275 (44%), Gaps = 43/275 (15%)
Query: 75 AQAIIEEAEIRWSEVSREVHEFEKD--ILKAISKKKG-SILATQKVMKYIEDMNRRRDNM 131
A+ + ++I+ +E+ R + E +K+ +LK+ S++K + + +K I+ + N
Sbjct: 463 AEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNF 522
Query: 132 KEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQF-------LETIEA 184
E+++ KN S ++ ML L++K +++ + + ++LK+ A + ++
Sbjct: 523 AEEMKAKNTS----QETMLRDLQEK--INQQENSLTLEKLKLAVADLEKQRDCSQDLLKK 576
Query: 185 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILL-------RKELLEKI--E 235
R + QL T + A S L + Y L +E L ++LL ++ E
Sbjct: 577 REHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESE 636
Query: 236 KETLQ---------VEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRM 286
KE LQ ++ + K+ N+R+R E + +R + N KS+ +
Sbjct: 637 KENLQSKINHLETCLKTQQIKSHEYNERVR--TLEMDRENLSVEIR-NLHNVLDSKSVEV 693
Query: 287 WERKV------EIAEMSLKGHRKAWNRMKITNEQL 315
+K+ + AE S + H+K M + QL
Sbjct: 694 ETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQL 728
Score = 36.6 bits (83), Expect = 0.031
Identities = 51/253 (20%), Positives = 111/253 (43%), Gaps = 32/253 (12%)
Query: 79 IEEAEIRWS----EVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEK 134
I E E+R E+ +V++F++ L+ + K K ++ +KV+ D R ++
Sbjct: 294 INELELRLQGHEKEMKGQVNKFQELQLQ-LEKAKVELIEKEKVLNKCRDELVRTTAQYDQ 352
Query: 135 LRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE-------TIEARNQ 187
K +L+ + KK+ L + + +E+ Q++K + +F E + + +Q
Sbjct: 353 ASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQ 412
Query: 188 ELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKEL---LEKIEKETLQVEED 244
E Q+K LQ +H ++ LDK ++++L LE+ +++ + E+
Sbjct: 413 ECIQMKARLTQELQ----QAKNMHNVLQ--AELDKLTSVKQQLENNLEEFKQKLCRAEQA 466
Query: 245 RAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKA 304
++ LR+ + E + +L + E+ R+V E LK ++
Sbjct: 467 FQASQIKENELRRSMEEMKK-------ENNLLKSHSEQK----AREVCHLEAELKNIKQC 515
Query: 305 WNRMKITNEQLQA 317
N+ + E+++A
Sbjct: 516 LNQSQNFAEEMKA 528
Score = 33.9 bits (76), Expect = 0.20
Identities = 53/264 (20%), Positives = 107/264 (40%), Gaps = 50/264 (18%)
Query: 34 SYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEI--------- 84
S V+ LK +T + EK L+ ++ LS K + + +E E+
Sbjct: 2021 SDVSELLKDKTHLQEK----LQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQ 2076
Query: 85 -RWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLK 143
R SE E K + A+ +K L + + + R EKLR++ + +
Sbjct: 2077 ARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGI----EKLRVRIEADE 2132
Query: 144 VQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNT-LQV 202
++ + +L+++E +++L D K+EN + + NQEL L + ++
Sbjct: 2133 KKQLHIAEKLKERERENDSLKD------KVENLERELQMSEENQELVILDAENSKAEVET 2186
Query: 203 LNAYKSKLHKAMEIY-------------------------LNLDKEILLRKELLEKIEKE 237
L ++ ++++++ LDK + K LLE+ E+
Sbjct: 2187 LKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQA 2246
Query: 238 TLQVEEDRAKAEAVNKRLRKQLAE 261
+Q++E+ A + + K+L E
Sbjct: 2247 EIQIKEESKTAVEMLQNQLKELNE 2270
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 51.2 bits (121), Expect = 1e-06
Identities = 61/257 (23%), Positives = 121/257 (47%), Gaps = 42/257 (16%)
Query: 74 YAQAIIEEAEIRWSEVSREVHE---FEKDILKAISKKKGSILATQKVM--KYIEDMNRRR 128
Y+Q +++ E ++ +H+ F ++ +A+S +ATQK +YIE++ + R
Sbjct: 148 YSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSA-----VATQKKKADRYIEELTKER 202
Query: 129 DNMKEKL--------RLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE 180
D + +L LK + K+Q K L++ E SE +V + K+E A+ L
Sbjct: 203 DALSLELYRNTITDEELKEKNAKLQEKLQLVE----SEKSEIQLNVKELKRKLERAKLLL 258
Query: 181 TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDK---EILLRKELLEKIEKE 237
+ E L G LQ ++A + E++ L++ E + R+E EKI++
Sbjct: 259 PQQQLQAEADHL----GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEW 312
Query: 238 TLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNA------DLEKSIR-----M 286
+++E K +++R+Q + R + M + +E+ + + E+ +R M
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
Query: 287 WERKVEIAEMSLKGHRK 303
WE++ +I E+ K H +
Sbjct: 373 WEKEEKIRELEEKMHEQ 389
Score = 42.0 bits (97), Expect = 7e-04
Identities = 58/268 (21%), Positives = 128/268 (47%), Gaps = 33/268 (12%)
Query: 45 EMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEI-RWSEVSREVHEFEKDILKA 103
E+ EK + + + R+Q R E KI + Q +EA++ R E RE E ++ K
Sbjct: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE--QEAKMWRQEEKIREQEEKIREQEKK 438
Query: 104 ISKKKGSILATQKVMKYIEDMNRRRDNM---KEKLRLKNVSLKVQRKKMLLQ--LRQKEE 158
+ +++ I +K+ + E+ + ++ M +EK+R + + Q++KM Q +R++EE
Sbjct: 439 MWRQEEKIHEQEKIRE--EEKRQEQEEMWRQEEKIR-EQEEIWRQKEKMHEQEKIRKQEE 495
Query: 159 V----SEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAM 214
E +HD + + + E + + + R QE + + + K+ +
Sbjct: 496 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE------------EKIREQEEKIREQE 543
Query: 215 EIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNK---RLRKQLAEFRAPQVMTYV 271
E+ ++++ ++E +++ EK Q E+ R + E + + ++R+Q + +
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE 603
Query: 272 REKILNADLEKSIRMWERKVEIAEMSLK 299
+E+++ EK MWE++ ++ E K
Sbjct: 604 QEEMMQEQEEK---MWEQEEKMCEQEEK 628
Score = 34.3 bits (77), Expect = 0.15
Identities = 52/304 (17%), Positives = 126/304 (41%), Gaps = 27/304 (8%)
Query: 14 HEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR----PPRLSEIKI 69
H G EL+ +L VEE N + + E + K++ +++ ++ E +
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 70 SAADYAQAIIEEAEIRWS---------EVSREVHEFEKDILKAISKKKGSILATQKVMKY 120
+ + + + E+ W E+ E E + + + + +K+ I ++ M
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388
Query: 121 IEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKI------- 173
E + + + +E+ +++ + +++ + RQ+E++ E + Q+ K+
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMW--RQEEKIREQEEKIREQEKKMWRQEEKI 446
Query: 174 -ENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLE 232
E + E + + QE + + + K K+H+ +I +E + R+E E
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI--RKQEEKVWRQE--E 502
Query: 233 KIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVE 292
K+ + ++ E K +++R+Q + R + +E+++ EK E+ E
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562
Query: 293 IAEM 296
+M
Sbjct: 563 QEKM 566
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 51.2 bits (121), Expect = 1e-06
Identities = 56/243 (23%), Positives = 114/243 (46%), Gaps = 35/243 (14%)
Query: 74 YAQAIIEEAEIRWSEVSREVHE---FEKDILKAISKKKGSILATQKVM--KYIEDMNRRR 128
Y+Q +++ E ++ +H+ F ++ +A+S +ATQK +YIE++ + R
Sbjct: 136 YSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSA-----VATQKKKADRYIEELTKER 190
Query: 129 DNMKEKL--------RLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE 180
D + +L LK + K+Q K L++ E SE +V + K+E A+ L
Sbjct: 191 DALSLELYRNTITDEELKEKNAKLQEKLQLVE----SEKSEIQLNVKELKRKLERAKLLL 246
Query: 181 TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQ 240
+ E L G LQ ++A + E++ L+++ EK+ ++ +
Sbjct: 247 PQQQLQAEADHL----GKELQSVSAKLQAQVEENELWNRLNQQ------QEEKMWRQEEK 296
Query: 241 VEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKG 300
++E K + +++R+Q + R + M + +E+ + E MWE++ +I E+ K
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE---MMWEKEEKIRELEEKM 353
Query: 301 HRK 303
H +
Sbjct: 354 HEQ 356
Score = 44.7 bits (104), Expect = 1e-04
Identities = 60/303 (19%), Positives = 129/303 (42%), Gaps = 26/303 (8%)
Query: 14 HEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAAD 73
H G EL+ +L VEE N + + EK + + E +R ++ E + +
Sbjct: 257 HLGKELQSVSAKLQAQVEENELWN---RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Query: 74 YAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKE 133
+ + + E+ W + + + E + +K+ I ++ M E + + + +E
Sbjct: 314 QEEKMRRQEEMMWEKEEKMRRQEE-----MMWEKEEKIRELEEKMHEQEKIREQEEKRQE 368
Query: 134 KLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLK 193
+ +++ + +++ + RQ+E++ E Q+ KI + E ++ + +++ + +
Sbjct: 369 EEKIREQEKRQEQEAKM--WRQEEKIRE-------QEEKIREQE--EMMQEQEEKMGEQE 417
Query: 194 LSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKI-EKETLQVEEDRAKAEAVN 252
+ + + K+ + E +K+I +E EKI E+E + E++ E
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKKI---REQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 253 KRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKV-EIAEMSLKGHRKAWNRMKIT 311
K ++ + M EKI + EK IR E K+ E EM + K W + +
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKI--REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 532
Query: 312 NEQ 314
EQ
Sbjct: 533 CEQ 535
>gi|153791839 sodium channel associated protein 1 [Homo sapiens]
Length = 688
Score = 50.8 bits (120), Expect = 2e-06
Identities = 69/321 (21%), Positives = 137/321 (42%), Gaps = 40/321 (12%)
Query: 24 IQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAE 83
I+LC ++E + L+TE EK +L+ + I A + ++EEA
Sbjct: 289 IRLCVTIQEANQ----LRTENTHLEKQTRELQAKCNELENERYEAIVRARNSMQLLEEAN 344
Query: 84 IRWSEVSREVHEFEKDILK---AISK--KKGSILATQKVMKYIEDMNRRRDNMKEKLRLK 138
++ S+ E + E+DI K +S+ + +I ++V + N + + E+L
Sbjct: 345 LQKSQALLEEKQKEEDIEKMKETVSRFVQDATIRTKKEVANTKKQCNIQISRLTEELSAL 404
Query: 139 NVSLKVQRKKMLLQLRQKEEVSEALHDV---------DFQQLKIENAQFLETIEARNQEL 189
+ ++ ++ +++K+ V E L + D+++L+ + +FL + R+++
Sbjct: 405 QMECAEKQGQIERVIKEKKAVEEELEKIYREGRGNESDYRKLEEMHQRFL--VSERSKDD 462
Query: 190 TQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAE 249
QL+L+ N K + E + I + +LE + V E R K +
Sbjct: 463 LQLRLTRAE-----NRIKQLETDSSEEISRYQEMIQKLQNVLESERENCGLVSEQRLKLQ 517
Query: 250 AVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWER--KVEIAEMS---------- 297
NK+LRK+ R + + K+ + +E + ER +V++ EM
Sbjct: 518 QENKQLRKETESLRKIALEAQKKAKVKISTMEHEFSIKERGFEVQLREMEDSNRNSIVEL 577
Query: 298 ---LKGHRKAWNRMKITNEQL 315
L +KA NR K ++L
Sbjct: 578 RHLLATQQKAANRWKEETKKL 598
Score = 33.1 bits (74), Expect = 0.34
Identities = 56/277 (20%), Positives = 111/277 (40%), Gaps = 47/277 (16%)
Query: 74 YAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKE 133
Y Q + E +++ V +E ++ A+ KK + +V I + N++E
Sbjct: 76 YYQKQVGEMKLQLENVIKENERLHSELKDAVEKKLEAFPLGTEVGTDIYADDETVRNLQE 135
Query: 134 KLRLKN------------VSLKVQRKKMLLQLRQKEEVSEALHD-------VDFQQL--- 171
+L+L N VS ++ R L Q E DFQQL
Sbjct: 136 QLQLANQEKTQAVELWQTVSQELDRLHKLYQEHMTEAQIHVFESQKQKDQLFDFQQLTKQ 195
Query: 172 --------KIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKE 223
++ N QFL+T+ ++ + QL+ + L K +L A+ +++
Sbjct: 196 LHVTNENMEVTNQQFLKTVTEQSVIIEQLR-------KKLRQAKLELRVAV---AKVEEL 245
Query: 224 ILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYV------REKILN 277
+ ++L +++K+ V + EA ++RL++ + + ++ V + + N
Sbjct: 246 TNVTEDLQGQMKKKEKDVVSAHGREEASDRRLQQLQSSIKQLEIRLCVTIQEANQLRTEN 305
Query: 278 ADLEKSIRMWERKV-EIAEMSLKGHRKAWNRMKITNE 313
LEK R + K E+ + +A N M++ E
Sbjct: 306 THLEKQTRELQAKCNELENERYEAIVRARNSMQLLEE 342
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 50.4 bits (119), Expect = 2e-06
Identities = 55/212 (25%), Positives = 100/212 (47%), Gaps = 24/212 (11%)
Query: 115 QKVMKYIEDMNRRRDNMKEKL---RLKNVSLKVQRKKMLLQLRQKE-EVSEALHDVDFQQ 170
+K +YIE++ + RD + +L + N LK + ++ +LR E E SE +V +
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 171 LKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKEL 230
K+E A+FL L Q++ NTLQ + + + E + +E + R+E
Sbjct: 215 RKLERAKFL---------LPQVQT---NTLQEEMWRQEEELREQEKKIRKQEEKMWRQE- 261
Query: 231 LEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNAD---LEKSIRMW 287
E++ ++ ++ E K KRLR+Q E R + ++K+ + E+ +MW
Sbjct: 262 -ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320
Query: 288 ERKVEIAEMSLKGHR---KAWNRMKITNEQLQ 316
E++ ++ E K R + W + K EQ Q
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Score = 31.6 bits (70), Expect = 1.00
Identities = 33/176 (18%), Positives = 79/176 (44%), Gaps = 12/176 (6%)
Query: 115 QKVMKYIEDMNRRRDNMKEK---LRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQL 171
++ M+ E M R M+E+ +R + ++ Q +KM Q + E E + + + +
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Query: 172 KIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELL 231
+ E + + E + QE ++ +Q + K+ + E ++++ +E
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ---EQEEKMWEQEEKMREQEEKM---REQE 666
Query: 232 EKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMW 287
EK++ + ++ E K + +++R+Q + R + + +E+ + EK MW
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEK---MW 719
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 48.9 bits (115), Expect = 6e-06
Identities = 72/336 (21%), Positives = 154/336 (45%), Gaps = 37/336 (11%)
Query: 17 SELELPVIQLCGLVEELSYVNSALKTETEMFEKYY-AKLEPRDQRPPRLSEIKISAADYA 75
+EL+ IQ+ L+++L NS ++ + + + Y +KLE ++ + +I + +
Sbjct: 854 TELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMI 913
Query: 76 QAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQ--KVMKYIEDMNRRRDNMKE 133
+ E + + E+ + ++D + ++++ + Q K+ K + ++ +K+
Sbjct: 914 LQM-REGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 972
Query: 134 KLRLKNVSLKVQRKKMLLQLRQKEEVSEA--LHDVDFQQLKIENA-QFLETIEARN-QEL 189
KL + LK + + L+L QKE+ A L I +A LET + + L
Sbjct: 973 KLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESL 1032
Query: 190 TQLKLSSGNTL-----QVLNAYKSKLHKAMEIYL--------NLDKEILLRKELLEKIEK 236
T++ N + + LN +L + EI L L ++ILL E++ K
Sbjct: 1033 TEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNK 1092
Query: 237 ETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKI--------LNADLEKSIR--- 285
E ++E+ K + L++QL + ++ V + +++ L DL KS++
Sbjct: 1093 EITWLKEEGVKQDTTLNELQEQLKQ-KSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENT 1151
Query: 286 -MWERKVEIAEMSLKGHRKA---WNRMKITNEQLQA 317
+ E+ VE+ ++ + RK +++K T+E+ Q+
Sbjct: 1152 FLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Score = 40.4 bits (93), Expect = 0.002
Identities = 47/224 (20%), Positives = 96/224 (42%), Gaps = 12/224 (5%)
Query: 105 SKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALH 164
S K+ L T + E ++ R ++E ++K++ + ++ K++ QLR + + E L
Sbjct: 304 SHKEQCTLLTSEKEALQEQLDER---LQELEKIKDLHM-AEKTKLITQLRDAKNLIEQLE 359
Query: 165 DVDFQQLKIENAQFLETIEARNQELTQLKLS-SGNTLQVLNAYKSKLHKAMEIYLNLDKE 223
+ Q ET+E + +E+ QL+ T Q + K + L+K
Sbjct: 360 QDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKA 419
Query: 224 ILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE--FRAPQVMTYVREKILNADLE 281
+ ++ E K +++E E ++ R L + R Q + V +K +
Sbjct: 420 LSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA 479
Query: 282 KSIRMWERKVEIAEMSL-----KGHRKAWNRMKITNEQLQADYL 320
K ++ E+++ E L R+ +MK+ E+ Q++YL
Sbjct: 480 KLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYL 523
Score = 40.4 bits (93), Expect = 0.002
Identities = 58/255 (22%), Positives = 118/255 (46%), Gaps = 30/255 (11%)
Query: 63 RLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIE 122
++ E KI D ++ + E+ E+ ++EK L+A+ + G T+ + + E
Sbjct: 1850 QILEQKIKELD--SCLVRQKEVHRVEMEELTSKYEK--LQALQQMDGRNKPTELLEENTE 1905
Query: 123 DMNRRR-------DNMKEK---LRLKNVSLKVQRKKM---LLQLRQKEEVSEALHDVDFQ 169
+ ++ NM+ + L K + +++K+ +++L++ + H + +
Sbjct: 1906 EKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELE 1965
Query: 170 QLKIENAQFLETIEARNQELTQLKLSSGNTL-QVLNAYKSKLHKA-----MEIYLNLDKE 223
LK E Q E E QE L+L +TL Q++ + ++L + M I ++K
Sbjct: 1966 ILKKEYDQ--EREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKA 2023
Query: 224 ILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEF---RAPQVMTYVREKILNADL 280
+ ELLE ++ET Q+ + A+ + KR K+ E R ++ VR+ L L
Sbjct: 2024 QEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRD--LQTQL 2081
Query: 281 EKSIRMWERKVEIAE 295
E+ + +++K+E E
Sbjct: 2082 EELQKKYQQKLEQEE 2096
Score = 38.1 bits (87), Expect = 0.011
Identities = 43/182 (23%), Positives = 80/182 (43%), Gaps = 4/182 (2%)
Query: 82 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLK-NV 140
AE ++ +E+ +KD L+ + K+ L K +Y ++ + +E L LK N
Sbjct: 1935 AEREKQKLGKEIVRLQKD-LRMLRKEHQQELEILK-KEYDQEREEKIKQEQEDLELKHNS 1992
Query: 141 SLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETI-EARNQELTQLKLSSGNT 199
+LK ++ QL QKE+ E + + A+ LE+ E NQ L ++ +
Sbjct: 1993 TLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDL 2052
Query: 200 LQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQL 259
+ Y+ L E +++ + E L+K ++ L+ EE+ L+ QL
Sbjct: 2053 KRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQL 2112
Query: 260 AE 261
A+
Sbjct: 2113 AQ 2114
Score = 35.4 bits (80), Expect = 0.069
Identities = 52/282 (18%), Positives = 122/282 (43%), Gaps = 35/282 (12%)
Query: 29 LVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRL-SEIKISAADYAQAIIEEAEIRWS 87
L+E+L + ET+ + + LE +++ +L S IK Q + E+R
Sbjct: 354 LIEQLEQDKGMVIAETK--RQMHETLEMKEEEIAQLRSRIK-------QMTTQGEELREQ 404
Query: 88 EVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR--RRDNMKEKLRLKNVSLKVQ 145
+ E FE ++ KA+S + + A +K+ +++ + + + +E++ L+ +V+
Sbjct: 405 KEKSERAAFE-ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVK 463
Query: 146 RKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNA 205
++ + + + EE L + ++L + + + ++ R +E +
Sbjct: 464 QEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQE-------------Q 510
Query: 206 YKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAP 265
K L K+ YL + +E K ++E+L +EE + +A+ +L + +
Sbjct: 511 MKVALEKSQSEYLKISQE---------KEQQESLALEELELQKKAILTESENKLRDLQQE 561
Query: 266 QVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNR 307
R L + LEKS++ + + + + L+ + N+
Sbjct: 562 AETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNK 603
Score = 31.6 bits (70), Expect = 1.00
Identities = 33/141 (23%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 37 NSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEF 96
NS LK ++ ++ +L ++Q + I+ A +A + E+ E
Sbjct: 1991 NSTLK---QLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESH----------QEE 2037
Query: 97 EKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQK 156
+LK I++K + T K +Y E ++ R + M K+R L+ +KK +L Q+
Sbjct: 2038 TNQLLKKIAEKDDDLKRTAK--RYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQE 2095
Query: 157 EEVSEALHDVDFQQLKIENAQ 177
E +V +L+ + AQ
Sbjct: 2096 ENPGN--DNVTIMELQTQLAQ 2114
>gi|45439370 TAO kinase 1 [Homo sapiens]
Length = 1001
Score = 48.9 bits (115), Expect = 6e-06
Identities = 47/184 (25%), Positives = 85/184 (46%), Gaps = 12/184 (6%)
Query: 91 REVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLR--LKNVSLKVQRKK 148
RE K +++ + K ++ K +D + + + LR L + K + K
Sbjct: 696 RERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKA 755
Query: 149 MLLQLRQKEEVSEAL--HDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAY 206
+L +L++++ A+ D ++ + Q L EA+ E LK+ L++LNAY
Sbjct: 756 VLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAY 815
Query: 207 KSKLHKAMEI-----YLNLDKEILLRKELLE-KIEKETLQVEEDRAKAEAVNKRLRKQLA 260
+SK+ E L++ + LR+ LLE KIE+E L ++ +R E + L +Q
Sbjct: 816 QSKIKMQAEAQHDRELRELEQRVSLRRALLEQKIEEEMLALQNER--TERIRSLLERQAR 873
Query: 261 EFRA 264
E A
Sbjct: 874 EIEA 877
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 48.9 bits (115), Expect = 6e-06
Identities = 68/306 (22%), Positives = 125/306 (40%), Gaps = 56/306 (18%)
Query: 53 KLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWS---------EVSR------------ 91
+LE RDQ + E + A + I+++ E+ W+ EV++
Sbjct: 123 ELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANK 182
Query: 92 ---EVHEFEKDILKAISKKK------GSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSL 142
E E KD+ K I K IL Q++ K ++ +R D M E R K++
Sbjct: 183 LRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQR 242
Query: 143 --KVQRKKMLLQLRQKEEVSEAL------HDVDFQQLKIENAQFLETIEARNQE------ 188
+++RK+ ++R + ++ E + + +Q + E Q LE +E +E
Sbjct: 243 QEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDME 302
Query: 189 -LTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAK 247
Q KL ++ +N K + L +E L + ++E +K+ + E A+
Sbjct: 303 RRQQQKLKMQAEIKRINDENQKQKAEL-----LAQEKLADQMVMEFTKKKMAREAEFEAE 357
Query: 248 AEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNR 307
E + + K++A RA Q EK + E+ +R E+A+ + K R
Sbjct: 358 QERIRREKEKEIARLRAMQ------EKAQDYQAEQDALRAKRNQEVADREWRRKEKENAR 411
Query: 308 MKITNE 313
K+ E
Sbjct: 412 KKMETE 417
Score = 33.9 bits (76), Expect = 0.20
Identities = 60/285 (21%), Positives = 122/285 (42%), Gaps = 30/285 (10%)
Query: 31 EELSYVNSALKTETEMFEKYYAKLEPRDQRP-PRLSEIKISAADYAQAIIEEAEIRWSEV 89
EE S + + E E +Y +L+ D + R + K+ + I +E + + +E+
Sbjct: 270 EERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAEL 329
Query: 90 SREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQ---R 146
+ ++ +++ KK + + I RR+ KE RL+ + K Q
Sbjct: 330 LAQEKLADQMVMEFTKKKMAREAEFEAEQERI-----RREKEKEIARLRAMQEKAQDYQA 384
Query: 147 KKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAY 206
++ L+ ++ +EV+ D ++++ + ENA R + T+ +L QV A+
Sbjct: 385 EQDALRAKRNQEVA----DREWRRKEKENA--------RKKMETEAELRKSRLEQV--AF 430
Query: 207 KSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQ 266
K A+++ + D+ + + E+IEKE L+ E+ LR+Q+ E + +
Sbjct: 431 KEHA-LAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKE 489
Query: 267 VMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKIT 311
V + A E+ R+ E + E + RK ++ T
Sbjct: 490 VQNRI------ATFEEGRRLKEEAQKRRERIDEIKRKKLEELRAT 528
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 48.1 bits (113), Expect = 1e-05
Identities = 62/318 (19%), Positives = 132/318 (41%), Gaps = 38/318 (11%)
Query: 30 VEELSYVNSALKTETEMFEKYYAKLEPRD----QRPPRLSEIKISAADYAQAIIEEAEIR 85
V ++ + + LK E + ++ KL+ Q +I+ + D + E EI+
Sbjct: 389 VIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIK 448
Query: 86 WSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQ 145
+E+ ++ + ++ K + +K + +K +ED+ R ++LR +K
Sbjct: 449 SNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCL 508
Query: 146 RKKMLLQLRQKEEVSEALHDVDFQQLKIENA--------QFLETIEARNQELTQLKLSSG 197
+ +LR ++E+S+ ++ Q+ +I+N Q E ++ QE+ LK
Sbjct: 509 EDE---RLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK---- 561
Query: 198 NTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELL----EKIEKETLQVEEDRAKAEAVNK 253
++ LN+ + L K +E + E+LL E L +++ E+ ++ K
Sbjct: 562 EEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSES 621
Query: 254 RLRKQLAEFRAPQVMTYVR---------EKILNADLEKSIRMWERKV------EIAEMSL 298
+L+ Q + + + R E++ E + R E K E+ + +
Sbjct: 622 QLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELV 681
Query: 299 KGHRKAWNRMKITNEQLQ 316
RK + +K +QLQ
Sbjct: 682 TQRRKHASSIKDLTKQLQ 699
Score = 34.7 bits (78), Expect = 0.12
Identities = 52/270 (19%), Positives = 112/270 (41%), Gaps = 49/270 (18%)
Query: 48 EKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAISKK 107
EK Y++ P D + KI + ++ ++EE E H + ++K
Sbjct: 133 EKTYSE-SPYDTDCTKKFISKIKSVSASEDLLEEIESELLSTEFAEHR----VPNGMNKG 187
Query: 108 KGSILATQKVM--KYIEDMNRRRDNMKEKLRLKNVSLKV-QRKKMLLQLRQKEEVSEALH 164
+ +++ +K + KY++ + + +KE + + + + + K L + +K +E H
Sbjct: 188 EHALVLFEKCVQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQH 247
Query: 165 DVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEI 224
+QL+ + + ++A +L +++ N +Q L+
Sbjct: 248 MNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLH-------------------- 287
Query: 225 LLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSI 284
KE+ +++E+ + EE R + EA+ VM YVR + + DL K
Sbjct: 288 ---KEMAQRMEQANKKCEEARQEKEAM---------------VMKYVRGEKESLDLRKEK 329
Query: 285 RMWERKVEIAEMSLKGHRKAWNRMKITNEQ 314
E+K+ A L+ K N++K +++
Sbjct: 330 ETLEKKLRDANKELE---KNTNKIKQLSQE 356
Score = 30.0 bits (66), Expect = 2.9
Identities = 47/278 (16%), Positives = 121/278 (43%), Gaps = 51/278 (18%)
Query: 88 EVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLK--VQ 145
++ E +++ K +K + +++ IE++N+ +++L ++V+ K VQ
Sbjct: 225 DICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQ 284
Query: 146 R--KKMLLQLRQ-KEEVSEALHDVDFQQLK--------IENAQFLETIEARNQELTQLKL 194
+ K+M ++ Q ++ EA + + +K ++ + ET+E + ++ +
Sbjct: 285 QLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELE 344
Query: 195 SSGNTLQVLNAYKSKLHKAME--------IYLNLDK---------------------EIL 225
+ N ++ L+ K +LH+ E + +DK E+
Sbjct: 345 KNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMD 404
Query: 226 LRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIR 285
KE +K+++ T ++ + + +A+ + K + + ++ E+I + +L+ +R
Sbjct: 405 SHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQE-------SEEIKSNELDAKLR 457
Query: 286 MWERKVEIAEMSLKGHRKAWNRMKITN-EQLQADYLAG 322
+ + ++E +M K + + KI E L+ + G
Sbjct: 458 VTKGELE-KQMQEKSDQLEMHHAKIKELEDLKRTFKEG 494
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 47.8 bits (112), Expect = 1e-05
Identities = 56/233 (24%), Positives = 110/233 (47%), Gaps = 34/233 (14%)
Query: 74 YAQAIIEEAEIRWSEVSREVHE---FEKDILKAISKKKGSILATQKVM--KYIEDMNRRR 128
Y+Q +++ E ++ +H+ F ++ +A+S +ATQK +YIE++ + R
Sbjct: 148 YSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSA-----VATQKKKADRYIEELTKER 202
Query: 129 DNMKEKL--------RLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE 180
D + +L LK + K+Q K L++ E SE +V + K+E A+ L
Sbjct: 203 DALSLELYRNTITDEELKEKNAKLQEKLQLVE----SEKSEIQLNVKELKRKLERAKLLL 258
Query: 181 TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDK---EILLRKELLEKIEKE 237
+ E L G LQ ++A + E++ L++ E + R+E EKI++
Sbjct: 259 PQQQLQAEADHL----GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEW 312
Query: 238 TLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERK 290
+++E K +++R+Q + R + M + +E+ + E MWE++
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE---MMWEKE 362
Score = 42.0 bits (97), Expect = 7e-04
Identities = 63/295 (21%), Positives = 126/295 (42%), Gaps = 27/295 (9%)
Query: 45 EMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEI-RWSEVSREVHEFEKDILKA 103
E+ EK + + + R+Q R E KI + Q +EA++ R E RE E ++ K
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE--QEAKMWRQEEKIREQEEKIREQEKK 452
Query: 104 ISKKKGSILATQKVMKYI-----EDMNRRRDNM---------KEKLRLKNVSLKVQRKKM 149
+ +++ I +K+ + E+M R+ + + KEK+ + ++ Q +K+
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 150 LLQ----LRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNA 205
Q Q+E++ E + Q+ KI + + E + E ++ Q
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 206 YKS--KLHKAMEIYLNLDKEIL----LRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQL 259
++ K+ + E +++I R+E EK+ K+ ++ E K + +++R+Q
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 260 AEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQ 314
+ R + MT +E+ + EK E+ E E + K + K EQ
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687
Score = 35.0 bits (79), Expect = 0.090
Identities = 50/241 (20%), Positives = 103/241 (42%), Gaps = 35/241 (14%)
Query: 79 IEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLK 138
I E E W E ++HE EK + +++ + Q+ + I + + +EK+R +
Sbjct: 540 IREQEEMWRE-EEKMHEQEKIWEEEKRQEQEDKMWRQE--EKIREQEEKVWRQEEKIREQ 596
Query: 139 NVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGN 198
+ Q +KM +Q+E++ E + Q+ KI + E I + +E+TQ
Sbjct: 597 EEKRQEQEEKMW---KQEEKIREQEEKIQEQEEKIREQE--EKIREQ-EEMTQ------- 643
Query: 199 TLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQ 258
E + +E + +E + ++ET+ +E++ + + K++R+Q
Sbjct: 644 --------------EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ--EKKIREQ 687
Query: 259 LAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN---RMKITNEQL 315
+ R + M +E+ + EK E+ E E + K W R++ E++
Sbjct: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
Query: 316 Q 316
Q
Sbjct: 748 Q 748
Score = 29.6 bits (65), Expect = 3.8
Identities = 26/144 (18%), Positives = 63/144 (43%), Gaps = 1/144 (0%)
Query: 45 EMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILKAI 104
E EK + + E ++ ++ E + + + I E+ E+ E ++ E E+ + +
Sbjct: 602 EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT-QEQEEKMGEQEEKMCEQE 660
Query: 105 SKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALH 164
K + + + I + ++ +EK+R + ++ Q +KM Q + E E +
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
Query: 165 DVDFQQLKIENAQFLETIEARNQE 188
+ + + + E + + + R QE
Sbjct: 721 EQEEKMRRQEEKMWEQEVRLRQQE 744
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 47.8 bits (112), Expect = 1e-05
Identities = 66/310 (21%), Positives = 142/310 (45%), Gaps = 46/310 (14%)
Query: 18 ELELPVIQLCGLVEEL---SYVNSALKTETEMFEKYYAKLEPRDQRPPRLS-----EIKI 69
ELE +L EEL + ++S L + E +++Y+ LE +QR ++ E KI
Sbjct: 201 ELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLE--EQRDHVIASKTGAESKI 258
Query: 70 SAADYA----QAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMN 125
+A + QA+I++ I +V+ E E E D++ + +K S+ K +E
Sbjct: 259 TALEQKEQELQALIQQLSIDLQKVTAETQEKE-DVITHLQEKVASL------EKRLEQNL 311
Query: 126 RRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEAR 185
++++E L+ K ++ + L + ++A++ ++ + ++E +T++A
Sbjct: 312 SGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELE-----QTLQAS 366
Query: 186 NQELTQLK---LSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVE 242
++L Q K + +Q L A + + L L+++ L R + LE + + +E
Sbjct: 367 EEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEA---QIVALE 423
Query: 243 EDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHR 302
RA + ++ +QL + NA L++ +ER ++ + LK +
Sbjct: 424 RTRAADQTTAEQGMRQLEQE--------------NAALKECRNEYERSLQNHQFELKKLK 469
Query: 303 KAWNRMKITN 312
+ W++ +I +
Sbjct: 470 EEWSQREIVS 479
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 47.8 bits (112), Expect = 1e-05
Identities = 64/302 (21%), Positives = 133/302 (44%), Gaps = 42/302 (13%)
Query: 30 VEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSE- 88
+E L+ VN L E+E +E L ++ +++K+ A ++ + + +
Sbjct: 610 IEHLTCVNHQL--ESEKYELKSKVLIMKETIESLENKLKVQAQKFSHVAGDSSHQKTEVN 667
Query: 89 ----VSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKV 144
V+ ++ D +S K+G + + Q +K +E+ + D + K+ ++ V
Sbjct: 668 SLRIVNEQLQRSVDDYQHRLSIKRGELESAQAQIKILEE---KIDELNLKMTSQDEEAHV 724
Query: 145 QRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLN 204
+K + + ++K+ + E VD + KI N Q E + + + + Q+K+ +++
Sbjct: 725 MKKTIGVIDKEKDFLQET---VDEKTEKIANLQ--ENLANKEKAVAQMKI-------MIS 772
Query: 205 AYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRA 264
+S +++ E +N D+EI + L+ KE +V R A N+RL+ LA
Sbjct: 773 ECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLA---- 828
Query: 265 PQVMTYVRE-KILNADLEKSIRMWERKVEIAEMSLKGHR-----KAWNRMKITNEQLQAD 318
T RE + ++ +LE +++ E EM + H+ W + E+ D
Sbjct: 829 ----TMARENQEISLELEAAVQ------EKEEMKSRVHKYITEVSRWESLMAAKEKENQD 878
Query: 319 YL 320
L
Sbjct: 879 LL 880
Score = 37.7 bits (86), Expect = 0.014
Identities = 57/264 (21%), Positives = 115/264 (43%), Gaps = 24/264 (9%)
Query: 76 QAIIEEAEIRWSEVSREVHEFEK-DILKAISKKKGSILATQKVMKY--IEDMN---RRRD 129
+A ++E E S V + + E + + L A +K+ L + M + ED + +
Sbjct: 842 EAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENQDLLDRFQMLHNRAEDWEVKAHQAE 901
Query: 130 NMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQEL 189
+RL+ +S+ +R+ LR++ E+ E +Q +A ++
Sbjct: 902 GESSSVRLELLSIDTERR----HLRERVELLEKEIQEHINAHHAYESQISSMAKAMSRLE 957
Query: 190 TQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAE 249
+L+ VLN S + + I L+ K+I+ ++ + +E E + VE + K+E
Sbjct: 958 EELRHQEDEKATVLNDLSSL--RELCIKLDSGKDIMTQQLNSKNLEFERVVVELENVKSE 1015
Query: 250 AVNKRLRKQLAEFR-----APQVMTYVREKILNADL-----EKSIRMWERKVEIAEMSLK 299
+ L+KQL+ R ++ R+K ++ L + I++ + K+ ++E L
Sbjct: 1016 S--DLLKKQLSNERHTVKNLESLLATNRDKEFHSHLTSHEKDTEIQLLKEKLTLSESKLT 1073
Query: 300 GHRKAWNRMKITNEQLQADYLAGK 323
+ ++ QLQ DY A K
Sbjct: 1074 SQSRENTMLRAKVAQLQTDYDALK 1097
Score = 30.8 bits (68), Expect = 1.7
Identities = 61/330 (18%), Positives = 136/330 (41%), Gaps = 40/330 (12%)
Query: 29 LVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSE 88
L+E V S + + EK +L DQ +L K + A + EA+
Sbjct: 294 LMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKR 353
Query: 89 VSREVHEFEKDILKA-----ISKKKGSILATQKVMKY-IEDMNRRRDNMKEKLRLKNVSL 142
E+ + E+ + K + +K+ L+ + ++K +E + + + K++L K S
Sbjct: 354 KLSEMQDLEETMAKLQLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVESF 413
Query: 143 KVQRKKMLLQLRQ--------KEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKL 194
V +++ L++ + + + S + D + ++ E + + +E + +
Sbjct: 414 AVTERQLTLEVERMRLEHGIKRRDRSPSRLDTFLKGIEEERDYYKKELERLQHIIQRRSC 473
Query: 195 SSGNTLQVLNA---------YKSKLHKAMEIYLNLDKEILLRKELLEKIEK--ETLQVEE 243
S+ + + ++ Y S++H+ L + + ++ +E I+ + L E
Sbjct: 474 STSYSAREKSSIFRTPEKGDYNSEIHQITRERDELQRMLERFEKYMEDIQSNVKLLTAER 533
Query: 244 DRA-----KAEAVNKRLRKQLAEFRAPQVMTYVREK---ILNADLEKSI----RMWERKV 291
D+ +A+ LRK+ + AP + + EK + +DL + + + E+
Sbjct: 534 DKLSVLYNEAQEELSALRKESTQTTAPHNIVSLMEKEKELALSDLRRIMAEKEALREKLE 593
Query: 292 EIAEMSLKGH---RKAWNRMKITNEQLQAD 318
I E+SL G K + N QL+++
Sbjct: 594 HIEEVSLFGKSELEKTIEHLTCVNHQLESE 623
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 47.8 bits (112), Expect = 1e-05
Identities = 58/275 (21%), Positives = 124/275 (45%), Gaps = 40/275 (14%)
Query: 37 NSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEF 96
N+A + +YY LE + + + + Y Q + E+ I E+ R+++E
Sbjct: 174 NAAEDKRNKAKAQYYLDLEKQLEEQEKKKQ-----EAYEQLLKEKLMI--DEIVRKIYEE 226
Query: 97 EKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKML----LQ 152
++ +K+ + + +YIE+ + + ++K K ++ + +K++ +Q
Sbjct: 227 DQ------LEKQQKLEKMNAMRRYIEEFQKEQALWRKK---KREEMEEENRKIIEFANMQ 277
Query: 153 LRQKEEVSEALHDVDFQQLKIENA--QFLETIEARNQELTQLKLSSGNTLQVLNAYKSKL 210
+++E+ + + + ++L+++NA Q LE + + ++L Q++ Q YKSKL
Sbjct: 278 QQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQA-EIYKSKL 336
Query: 211 HKAMEIYLNLDKEI-------LLRKELLEKIEKETLQ----------VEEDRAKAEAVNK 253
+ E L KE+ + KEL+ + KE + E+DR + K
Sbjct: 337 KEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQK 396
Query: 254 RLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWE 288
+ KQL RA + + R + AD ++ + W+
Sbjct: 397 QRMKQLEHRRAVEKLIEERRQQFLADKQRELEEWQ 431
Score = 32.7 bits (73), Expect = 0.45
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 20/169 (11%)
Query: 123 DMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETI 182
DM +E RLK + LK Q +K+ ++L + + E+L D +Q EN+ L +
Sbjct: 68 DMEEAIQKAEENKRLKELQLK-QEEKLAMELAKLKH--ESLKDEKMRQQVRENSIELREL 124
Query: 183 EARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLE---KIEKETL 239
E ++L ++ Q+ K Y + ++ + K ++E +I KE
Sbjct: 125 E---KKLKAAYMNKERAAQIAEKDAIK-------YEQMKRDAEIAKTMMEEHKRIIKEEN 174
Query: 240 QVEEDRAKAEA-VNKRLRKQLAEFRAPQVMTY---VREKILNADLEKSI 284
E+ R KA+A L KQL E + Y ++EK++ ++ + I
Sbjct: 175 AAEDKRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKI 223
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 47.4 bits (111), Expect = 2e-05
Identities = 67/319 (21%), Positives = 133/319 (41%), Gaps = 49/319 (15%)
Query: 31 EELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVS 90
+EL + L+ E L RD+ +L E+ S A+A E+ E
Sbjct: 279 KELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAE 338
Query: 91 REVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKML 150
E+H + L +K+ S+L E+M+RR +N + + K + ++ K
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLR--------EEMHRRFENAPDSAKTKALQTVIEMKDSK 390
Query: 151 LQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKL 210
+ ++ L D++ + +++ L T E R +E+ Q+++ ++ K+K+
Sbjct: 391 ISSMER-----GLRDLEEEIQMLKSNGALST-EEREEEMKQMEVYRSHS----KFMKNKI 440
Query: 211 HKAMEIYLNLDKEILLRKELLE-------------KIEKETLQVEEDRA-----KAEAVN 252
+ + D E+L + LE ++ KE+L +E RA + +A+
Sbjct: 441 GQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALR 500
Query: 253 KRLRKQ--LAEFRAPQVMTYVREKILNA----DL-------EKSIRMWERKVEIAEMSLK 299
RL ++ + + Q+ EK A DL E+ + + ++K+E + L+
Sbjct: 501 LRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLR 560
Query: 300 GHRKAWNRMKITNEQLQAD 318
K + +K + LQAD
Sbjct: 561 DKEKQMSSLKERVKSLQAD 579
Score = 29.6 bits (65), Expect = 3.8
Identities = 48/247 (19%), Positives = 102/247 (41%), Gaps = 31/247 (12%)
Query: 73 DYAQAIIEEAEIRWSEVSREVHEFEKDILK---AISKKKGSILATQKVMKYIEDMNRRRD 129
D + +E E + S + F LK A+ K + S + K + +
Sbjct: 166 DLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRV--VQEENQ 223
Query: 130 NMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEA-------LHDVDFQQLKIENAQFLETI 182
+M+ ++ L++QR L QL Q++ S L + +FQ+L E+ + + +
Sbjct: 224 HMQMTIQALQDELRIQRD--LNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKEL 281
Query: 183 EARNQELTQLKLSSGNTLQVLNAYKSKLHKAME------IYLNLDKEILLRKELLEKIEK 236
+ L +++L Q LNA + K +E + +E R L + E
Sbjct: 282 FLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEM 341
Query: 237 ETLQVEEDRAKAEAVNKRLRKQL----------AEFRAPQVMTYVREKILNADLEKSIRM 286
+E + E N LR+++ A+ +A Q + +++ +++ +E+ +R
Sbjct: 342 HVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISS-MERGLRD 400
Query: 287 WERKVEI 293
E ++++
Sbjct: 401 LEEEIQM 407
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 47.4 bits (111), Expect = 2e-05
Identities = 63/276 (22%), Positives = 129/276 (46%), Gaps = 29/276 (10%)
Query: 25 QLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIE---- 80
QL LVEELS+ ++ + + +KL + + ++K +++ E
Sbjct: 529 QLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELK 588
Query: 81 -EAEIRWSEVSREVHEFEKD-ILKAISKKKGSILA---TQKVMKYIEDMNRRRDNMKEKL 135
EAE+ ++ E+ E EK+ +L +++ + + L TQ + + E++++ +KE L
Sbjct: 589 HEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSK----LKEDL 644
Query: 136 RLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLS 195
+++ + +++ K L + K+++ +++ KIE QF + Q L++S
Sbjct: 645 EIEH-RINIEKLKDNLGIHYKQQIDGLQNEMS---QKIETMQFEKDNLITKQNQLILEIS 700
Query: 196 SGNTLQVLNAYKSKLHKAMEIYLN-LDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKR 254
LQ + + + M + +N L KEI E+L + EKE +E++ + + +
Sbjct: 701 KLKDLQ--QSLVNSKSEEMTLQINELQKEI----EILRQEEKEKGTLEQEVQELQLKTEL 754
Query: 255 LRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERK 290
L KQ+ E ++EK + E SI E+K
Sbjct: 755 LEKQMKEKE-----NDLQEKFAQLEAENSILKDEKK 785
Score = 43.5 bits (101), Expect = 3e-04
Identities = 58/293 (19%), Positives = 131/293 (44%), Gaps = 24/293 (8%)
Query: 29 LVEELSYVNSALKTETEMFEKYYAKLEP-RDQRPPRLSEIKISAADYAQAIIEEAEIRWS 87
L EL+ L+T + K+ +LE R + + E+ + A + E++W
Sbjct: 3164 LKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQW- 3222
Query: 88 EVSREVHEFEKDILKAISKKKGSI-LATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQR 146
A+ K+K + + ++ + +ED+ ++ K++ N+ L+ Q+
Sbjct: 3223 ---------------ALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLE-QQ 3266
Query: 147 KKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAY 206
K++L + +QK E L+D + + N + +E+ + ++ S+ + + L+A
Sbjct: 3267 KQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMS-STLDRERELHAQ 3325
Query: 207 KSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEE---DRAKAEAVNKRLRKQLAEFR 263
+ L E LL KEL +++E++ ++ E + K + + + R+Q+ + R
Sbjct: 3326 LQSSDGTGQSRPPLPSEDLL-KELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDR 3384
Query: 264 APQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQ 316
T E+ N + +K + + KVE + L+ R+ ++ + ++LQ
Sbjct: 3385 QVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQ 3437
Score = 39.7 bits (91), Expect = 0.004
Identities = 43/223 (19%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Query: 84 IRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMK-EKLRLKNVSL 142
+R E+ ++++ IS + + A +K+++ I + + + ++ K + L S
Sbjct: 1826 VRSGFAGTEIDPENEELMLNISSRLQA--AVEKLLEAISETSSQLEHAKVTQTELMRESF 1883
Query: 143 KVQRKKMLLQLRQKEEVSEALHDVDF--QQLKIENAQFLETIEARNQELTQLKLSSGNTL 200
+ Q+++ L+ +EE+ E LH+ +QL +E ++ I+ E T
Sbjct: 1884 R-QKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKT---------- 1932
Query: 201 QVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDR-----------AKAE 249
++ ++ + +I L++E+L L+++E E Q++E+R A+A
Sbjct: 1933 ----LFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAG 1988
Query: 250 AVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVE 292
V ++L ++ + ++ + + + DL+K ++ E VE
Sbjct: 1989 PVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVE 2031
Score = 35.0 bits (79), Expect = 0.090
Identities = 47/237 (19%), Positives = 107/237 (45%), Gaps = 23/237 (9%)
Query: 95 EFEKDILKAISKKKGSI-----LATQKVMKYIEDMNRRRDNM-KEKLRLKNVSLKVQRKK 148
E + +L+ KKK +K+ Y + +++ +N KE+++ K ++ K
Sbjct: 278 EEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTK 337
Query: 149 MLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKS 208
++ + ++ E+ + L D +++ E I +NQE+ +KL N+ Q
Sbjct: 338 IIEEEKKTLELKDKLTTADKLLGELQ-----EQIVQKNQEIKNMKLELTNSKQKERQSSE 392
Query: 209 KLHKAM----EIYLNLDKEILLRKELLEKIEKET-LQVEEDRAKAEAVNKRLRKQLAEFR 263
++ + M E+ K+ ++++++E+ET ++E+ RA+ + + + Q+ +
Sbjct: 393 EIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQEL 452
Query: 264 APQVMTYVREKIL--NADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKI----TNEQ 314
Q M + E ++E ++R + + + E +K A N + I TN Q
Sbjct: 453 IRQHMAQMEEMKTRHKGEMENALRSYS-NITVNEDQIKLMNVAINELNIKLQDTNSQ 508
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/236 (20%), Positives = 110/236 (46%), Gaps = 42/236 (17%)
Query: 43 ETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILK 102
E +FE+ +++ + RL + + A++ Q + EAE + + RE+ +K+ +K
Sbjct: 1930 EKTLFER---QIQEKTDIIDRLEQELLCASNRLQEL--EAEQQQIQEERELLSRQKEAMK 1984
Query: 103 AISK--KKGSILATQKVMKYIEDMN----RRRDNMKEKLRL----------KNVSLKVQR 146
A + ++ + T+K+MK ++ + RD+++++++ + + L+ ++
Sbjct: 1985 AEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEK 2044
Query: 147 KKMLLQLRQK----------------EEVSEALHDVDFQQLKIENAQFLETIEARNQELT 190
L+ LRQ+ E+ + H+ D Q +I+ + + R Q ++
Sbjct: 2045 NTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPIS 2104
Query: 191 QLKLSSGNTLQVLNAYKSKLHKAMEIYLN---LDKEILLRKELLEKIEKETLQVEE 243
+ + + Q+ N K K K E+ L+ L ++I R E +EK+E ++E+
Sbjct: 2105 EHQ--TREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQ 2158
Score = 31.6 bits (70), Expect = 1.00
Identities = 52/270 (19%), Positives = 115/270 (42%), Gaps = 48/270 (17%)
Query: 79 IEEAEIRWSEVSREVHEFEKDILKAIS--KKKGSILATQKVMKYIEDMNRRRDNMKEKLR 136
++E +++ + +++ E E D+ + + + + SIL +K K +EDM + + ++ R
Sbjct: 745 VQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEK--KTLEDMLKIHTPVSQEER 802
Query: 137 L----------------KNVSLKVQR----KKMLLQLRQKEE-------VSEALHDVDFQ 169
L K + + ++ K+ +QL ++ E +E +V++Q
Sbjct: 803 LIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQ 862
Query: 170 QLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLH---------KAMEIYLNL 220
+L+ E A L+ + + +L + L+ LN +LH K +
Sbjct: 863 ELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALN---EELHLQRINPTTVKMKSSVFDE 919
Query: 221 DKEILLRK-ELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNAD 279
DK + E+ E +EK+T ++ E + L ++L++ + LN +
Sbjct: 920 DKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEE 979
Query: 280 LEKSIRMWERKVEIAEMSLK---GHRKAWN 306
+ KS++ + +V + L+ H +A N
Sbjct: 980 V-KSLKQEKEQVSLRCRELEIIINHNRAEN 1008
Score = 29.3 bits (64), Expect = 4.9
Identities = 49/228 (21%), Positives = 102/228 (44%), Gaps = 26/228 (11%)
Query: 43 ETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAE--IRWSEVSREVH-EFEKD 99
ETEM +K L+ ++ E K++AA +Q +E + ++ + ++ + E E+
Sbjct: 2532 ETEMLQKKIVNLQ-------KIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERT 2584
Query: 100 ILKAISKKKGSILATQ--KVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKE 157
++ +++ + L + + I ++ + M L L+ +++ K +L + ++
Sbjct: 2585 NIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLL 2644
Query: 158 EVSEALHDVDFQQLKIENAQFLETIEA--RNQELTQLKLSSG--NTLQVLNAYKSKLHKA 213
E+ + L + +Q + E + + +E EL SG N L+ L A +S KA
Sbjct: 2645 ELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRA-ESVATKA 2703
Query: 214 MEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 261
E+ KE EK+++E L E + + ++R LAE
Sbjct: 2704 ---------ELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAE 2742
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 47.4 bits (111), Expect = 2e-05
Identities = 63/276 (22%), Positives = 129/276 (46%), Gaps = 29/276 (10%)
Query: 25 QLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIE---- 80
QL LVEELS+ ++ + + +KL + + ++K +++ E
Sbjct: 529 QLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELK 588
Query: 81 -EAEIRWSEVSREVHEFEKD-ILKAISKKKGSILA---TQKVMKYIEDMNRRRDNMKEKL 135
EAE+ ++ E+ E EK+ +L +++ + + L TQ + + E++++ +KE L
Sbjct: 589 HEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSK----LKEDL 644
Query: 136 RLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLS 195
+++ + +++ K L + K+++ +++ KIE QF + Q L++S
Sbjct: 645 EIEH-RINIEKLKDNLGIHYKQQIDGLQNEMS---QKIETMQFEKDNLITKQNQLILEIS 700
Query: 196 SGNTLQVLNAYKSKLHKAMEIYLN-LDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKR 254
LQ + + + M + +N L KEI E+L + EKE +E++ + + +
Sbjct: 701 KLKDLQ--QSLVNSKSEEMTLQINELQKEI----EILRQEEKEKGTLEQEVQELQLKTEL 754
Query: 255 LRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERK 290
L KQ+ E ++EK + E SI E+K
Sbjct: 755 LEKQMKEKE-----NDLQEKFAQLEAENSILKDEKK 785
Score = 43.5 bits (101), Expect = 3e-04
Identities = 58/293 (19%), Positives = 131/293 (44%), Gaps = 24/293 (8%)
Query: 29 LVEELSYVNSALKTETEMFEKYYAKLEP-RDQRPPRLSEIKISAADYAQAIIEEAEIRWS 87
L EL+ L+T + K+ +LE R + + E+ + A + E++W
Sbjct: 3156 LKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQW- 3214
Query: 88 EVSREVHEFEKDILKAISKKKGSI-LATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQR 146
A+ K+K + + ++ + +ED+ ++ K++ N+ L+ Q+
Sbjct: 3215 ---------------ALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLE-QQ 3258
Query: 147 KKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAY 206
K++L + +QK E L+D + + N + +E+ + ++ S+ + + L+A
Sbjct: 3259 KQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMS-STLDRERELHAQ 3317
Query: 207 KSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEE---DRAKAEAVNKRLRKQLAEFR 263
+ L E LL KEL +++E++ ++ E + K + + + R+Q+ + R
Sbjct: 3318 LQSSDGTGQSRPPLPSEDLL-KELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDR 3376
Query: 264 APQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQ 316
T E+ N + +K + + KVE + L+ R+ ++ + ++LQ
Sbjct: 3377 QVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQ 3429
Score = 39.7 bits (91), Expect = 0.004
Identities = 43/223 (19%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Query: 84 IRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMK-EKLRLKNVSL 142
+R E+ ++++ IS + + A +K+++ I + + + ++ K + L S
Sbjct: 1826 VRSGFAGTEIDPENEELMLNISSRLQA--AVEKLLEAISETSSQLEHAKVTQTELMRESF 1883
Query: 143 KVQRKKMLLQLRQKEEVSEALHDVDF--QQLKIENAQFLETIEARNQELTQLKLSSGNTL 200
+ Q+++ L+ +EE+ E LH+ +QL +E ++ I+ E T
Sbjct: 1884 R-QKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKT---------- 1932
Query: 201 QVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDR-----------AKAE 249
++ ++ + +I L++E+L L+++E E Q++E+R A+A
Sbjct: 1933 ----LFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAG 1988
Query: 250 AVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVE 292
V ++L ++ + ++ + + + DL+K ++ E VE
Sbjct: 1989 PVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVE 2031
Score = 36.2 bits (82), Expect = 0.040
Identities = 60/291 (20%), Positives = 133/291 (45%), Gaps = 49/291 (16%)
Query: 43 ETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVSREVHEFEKDILK 102
E +FE+ +++ + RL + + A++ Q + EAE + + RE+ +K+ +K
Sbjct: 1930 EKTLFER---QIQEKTDIIDRLEQELLCASNRLQEL--EAEQQQIQEERELLSRQKEAMK 1984
Query: 103 AISK--KKGSILATQKVMKYIEDMN----RRRDNMKEKLRL----------KNVSLKVQR 146
A + ++ + T+K+MK ++ + RD+++++++ + + L+ ++
Sbjct: 1985 AEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEK 2044
Query: 147 KKMLLQLRQK----------------EEVSEALHDVDFQQLKIENAQFLETIEARNQELT 190
L+ LRQ+ E+ + H+ D Q +I+ + + R Q ++
Sbjct: 2045 NTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPIS 2104
Query: 191 QLKLSSGNTLQVLNAYKSKLHKAMEIYLN---LDKEILLRKELLEKIEKETLQVE----- 242
+ + + Q+ N K K K E+ L+ L ++I R E +EK+E ++E
Sbjct: 2105 EHQ--TREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLV 2162
Query: 243 EDRAKAEAVNKRLRKQL-AEFRAPQVMTYVREKILNADLEKSIRMWERKVE 292
EDR AV + L + +A + +EK + +LE+ + + ++E
Sbjct: 2163 EDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEI-TNLEEQLEQFREELE 2212
Score = 35.0 bits (79), Expect = 0.090
Identities = 47/237 (19%), Positives = 107/237 (45%), Gaps = 23/237 (9%)
Query: 95 EFEKDILKAISKKKGSI-----LATQKVMKYIEDMNRRRDNM-KEKLRLKNVSLKVQRKK 148
E + +L+ KKK +K+ Y + +++ +N KE+++ K ++ K
Sbjct: 278 EEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTK 337
Query: 149 MLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKS 208
++ + ++ E+ + L D +++ E I +NQE+ +KL N+ Q
Sbjct: 338 IIEEEKKTLELKDKLTTADKLLGELQ-----EQIVQKNQEIKNMKLELTNSKQKERQSSE 392
Query: 209 KLHKAM----EIYLNLDKEILLRKELLEKIEKET-LQVEEDRAKAEAVNKRLRKQLAEFR 263
++ + M E+ K+ ++++++E+ET ++E+ RA+ + + + Q+ +
Sbjct: 393 EIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQEL 452
Query: 264 APQVMTYVREKIL--NADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKI----TNEQ 314
Q M + E ++E ++R + + + E +K A N + I TN Q
Sbjct: 453 IRQHMAQMEEMKTRHKGEMENALRSYS-NITVNEDQIKLMNVAINELNIKLQDTNSQ 508
Score = 31.6 bits (70), Expect = 1.00
Identities = 52/270 (19%), Positives = 115/270 (42%), Gaps = 48/270 (17%)
Query: 79 IEEAEIRWSEVSREVHEFEKDILKAIS--KKKGSILATQKVMKYIEDMNRRRDNMKEKLR 136
++E +++ + +++ E E D+ + + + + SIL +K K +EDM + + ++ R
Sbjct: 745 VQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEK--KTLEDMLKIHTPVSQEER 802
Query: 137 L----------------KNVSLKVQR----KKMLLQLRQKEE-------VSEALHDVDFQ 169
L K + + ++ K+ +QL ++ E +E +V++Q
Sbjct: 803 LIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQ 862
Query: 170 QLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLH---------KAMEIYLNL 220
+L+ E A L+ + + +L + L+ LN +LH K +
Sbjct: 863 ELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALN---EELHLQRINPTTVKMKSSVFDE 919
Query: 221 DKEILLRK-ELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNAD 279
DK + E+ E +EK+T ++ E + L ++L++ + LN +
Sbjct: 920 DKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEE 979
Query: 280 LEKSIRMWERKVEIAEMSLK---GHRKAWN 306
+ KS++ + +V + L+ H +A N
Sbjct: 980 V-KSLKQEKEQVSLRCRELEIIINHNRAEN 1008
Score = 29.3 bits (64), Expect = 4.9
Identities = 49/228 (21%), Positives = 102/228 (44%), Gaps = 26/228 (11%)
Query: 43 ETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAE--IRWSEVSREVH-EFEKD 99
ETEM +K L+ ++ E K++AA +Q +E + ++ + ++ + E E+
Sbjct: 2524 ETEMLQKKIVNLQ-------KIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERT 2576
Query: 100 ILKAISKKKGSILATQ--KVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKE 157
++ +++ + L + + I ++ + M L L+ +++ K +L + ++
Sbjct: 2577 NIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLL 2636
Query: 158 EVSEALHDVDFQQLKIENAQFLETIEA--RNQELTQLKLSSG--NTLQVLNAYKSKLHKA 213
E+ + L + +Q + E + + +E EL SG N L+ L A +S KA
Sbjct: 2637 ELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRA-ESVATKA 2695
Query: 214 MEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 261
E+ KE EK+++E L E + + ++R LAE
Sbjct: 2696 ---------ELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAE 2734
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 47.4 bits (111), Expect = 2e-05
Identities = 58/260 (22%), Positives = 116/260 (44%), Gaps = 40/260 (15%)
Query: 37 NSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQA--IIEEAEIRWSEVSREVH 94
N + K + F+ YY P+D +Y Q + E+ +R + + +
Sbjct: 83 NKSAKQQEVQFKAYYL---PKDD-------------EYYQFCYVDEDGVVRGASIPFQFR 126
Query: 95 -EFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQL 153
E E+DIL ++ TQ ++ IE N+ ++L+ +SL+ Q M +L
Sbjct: 127 PENEEDIL---------VVTTQGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAEL 177
Query: 154 RQKEEVSEALHDVDFQ-QLKI-ENAQFLET----IEARNQELTQLKLSSGNTLQVLNAYK 207
++K+E E L ++ + +LK+ E + ET ++ +NQ+++ G + L A
Sbjct: 178 QKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQL 237
Query: 208 SKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQV 267
S K ME + D++ + E LE+++KE + + K+L + + + + +
Sbjct: 238 STQEKEMEKLVQGDQD---KTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNET 294
Query: 268 MTYVREKIL---NADLEKSI 284
+++ L N DL K +
Sbjct: 295 TAMKKQQELMDENFDLSKRL 314
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 47.0 bits (110), Expect = 2e-05
Identities = 53/213 (24%), Positives = 99/213 (46%), Gaps = 26/213 (12%)
Query: 115 QKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQK-----EEVSEALHDVDFQ 169
+K +YIE++ + RD + +L +N + KK +L++K E SE +V
Sbjct: 193 KKADRYIEELTKERDALSLEL-YRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKEL 251
Query: 170 QLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKE 229
+ K+E A+FL L Q++ NTLQ + + + E + +E + R+E
Sbjct: 252 KRKLERAKFL---------LPQVQT---NTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299
Query: 230 LLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNAD---LEKSIRM 286
E++ ++ ++ E K KRLR+Q E R + ++++ + E+ +M
Sbjct: 300 --ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM 357
Query: 287 WERKVEIAEMSLKGHR---KAWNRMKITNEQLQ 316
WE++ ++ E K R + W + K EQ Q
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 47.0 bits (110), Expect = 2e-05
Identities = 60/302 (19%), Positives = 142/302 (47%), Gaps = 17/302 (5%)
Query: 17 SELELPVIQLCGLVEELSYV--NSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADY 74
S+ E +++L L ++ S N LK E+ EK + L +++ ++S +K++
Sbjct: 395 SDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLS-QEKEELQMSLLKLNNE-- 451
Query: 75 AQAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRR-RDNMKE 133
+I+ R + E+H+ ++ + SI + ++ IE+++R+ ++ K
Sbjct: 452 -YEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKH 510
Query: 134 KLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLK 193
+ +K+ K Q + + + K+++++ V QL+ + + ++ + ++L Q +
Sbjct: 511 MILIKDQLSKQQNEGDSIISKLKQDLNDEKKRV--HQLEDDKMDITKELDVQKEKLIQSE 568
Query: 194 LSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNK 253
++ L L+ K KL +E NL ++ +E I+KE L+++E + E
Sbjct: 569 VA----LNDLHLTKQKLEDKVE---NLVDQLNKSQESNVSIQKENLELKEHIRQNEEELS 621
Query: 254 RLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNE 313
R+R +L + + ++ +L + E +R ++ + E + +K +K+ NE
Sbjct: 622 RIRNELMQSLNQDSNSNFKDTLLK-EREAEVRNLKQNLSELEQLNENLKKVAFDVKMENE 680
Query: 314 QL 315
+L
Sbjct: 681 KL 682
Score = 37.7 bits (86), Expect = 0.014
Identities = 45/245 (18%), Positives = 110/245 (44%), Gaps = 25/245 (10%)
Query: 100 ILKAISKKKGSILATQKVMK--YIEDMNRRRDNMKEKLRLKNVSLKVQR--KKMLLQLRQ 155
I++ + +KG I A K +E+ N+ ++E +N++ + + L++L Q
Sbjct: 710 IVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQ 769
Query: 156 KEEVSEALHDVDFQQLKIENAQFLETIEARNQE---LTQLKLSSGNTLQVLNAYKSKLHK 212
K+++ A + +Q+ ++ + + + + +E LTQL ++ L SKL +
Sbjct: 770 KKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQE 829
Query: 213 AMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQ---LAEFRAPQVMT 269
++ Y ++ + ++ +E+ ++ ++E+ + +RLR++ A P+ +
Sbjct: 830 ELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLD 889
Query: 270 YVRE--------KILNADLEKSIRMWERKVEIAE-------MSLKGHRKAWNRMKITNEQ 314
V E + LE+ I+ ++ +E SL+ +K + + +EQ
Sbjct: 890 SVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQ 949
Query: 315 LQADY 319
+ A +
Sbjct: 950 MNATH 954
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 46.6 bits (109), Expect = 3e-05
Identities = 36/175 (20%), Positives = 87/175 (49%), Gaps = 20/175 (11%)
Query: 101 LKAISKKKGSILATQKVMKYIE-DMNRRRDNMKEKL-RLKNVSLKVQRKKMLLQL--RQK 156
+K + I+ Q+ +E D+ + D +K++ ++++ +VQR+ LQ QK
Sbjct: 332 IKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQK 391
Query: 157 EEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEI 216
++V E L ++D Q+ ++E ++L +++ Q++++ K++L
Sbjct: 392 QQVQELLDELDEQKAQLE------------EQLKEVRKKCAEEAQLISSLKAELTSQESQ 439
Query: 217 YLNLDKEILLRKELLEKIEKETLQVEED----RAKAEAVNKRLRKQLAEFRAPQV 267
++E+ +E L ++++ET ++EE +A+ E + + L+ E + Q+
Sbjct: 440 ISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 35.8 bits (81), Expect = 0.053
Identities = 29/145 (20%), Positives = 61/145 (42%), Gaps = 4/145 (2%)
Query: 179 LETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKET 238
++ ++ N E+ L+ N Q L + + + +L E+ L+K++ +
Sbjct: 332 IKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQK 391
Query: 239 LQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSL 298
QV+E + + +L +QL E R E L + L+ + E ++ E L
Sbjct: 392 QQVQELLDELDEQKAQLEEQLKEVR----KKCAEEAQLISSLKAELTSQESQISTYEEEL 447
Query: 299 KGHRKAWNRMKITNEQLQADYLAGK 323
R+ +R++ +L+ +GK
Sbjct: 448 AKAREELSRLQQETAELEESVESGK 472
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 46.6 bits (109), Expect = 3e-05
Identities = 59/294 (20%), Positives = 132/294 (44%), Gaps = 42/294 (14%)
Query: 25 QLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEI 84
Q+ L +L++ SA+ +E E ++ +E +D+ L+ S + +E E
Sbjct: 364 QMSDLRVQLNF--SAMASELEEVKRC---MERKDKEKAHLA----SQVENLTRELENGEK 414
Query: 85 RWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKV 144
+ ++ + E + +++K + L ++ ++ ED ++ + +L+ ++ +LK
Sbjct: 415 QQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQ-QSEALKE 473
Query: 145 QRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLN 204
+ +K L+ K + S +Q K+++ + +E +++ + +L + L+ +
Sbjct: 474 EAEKRREDLKLKAQES-------IRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKD 526
Query: 205 AYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRA 264
K++L+ A++ NL RKEL + + K LQ EE +K E +L + ++
Sbjct: 527 ELKTQLYAALQQIENL------RKELNDVLTKRALQEEELHSKEE--------KLRDIKS 572
Query: 265 PQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQAD 318
Q ADLE ++ + E LK K ++MK+ L+ +
Sbjct: 573 HQ-----------ADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEE 615
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,142,593
Number of Sequences: 37866
Number of extensions: 403901
Number of successful extensions: 3421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 533
Number of HSP's that attempted gapping in prelim test: 2462
Number of HSP's gapped (non-prelim): 1271
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.