Guide to the Human Genome
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Search of human proteins with 214830451

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|214830451 sequestosome 1 isoform 2 [Homo sapiens]
         (356 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|214830451 sequestosome 1 isoform 2 [Homo sapiens]                  751   0.0  
gi|214830438 sequestosome 1 isoform 2 [Homo sapiens]                  751   0.0  
gi|4505571 sequestosome 1 isoform 1 [Homo sapiens]                    751   0.0  
gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]                    55   7e-08
gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]                    55   7e-08
gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]                    55   7e-08
gi|30348954 mindbomb homolog 1 [Homo sapiens]                          48   1e-05
gi|126032348 hect domain and RLD 2 [Homo sapiens]                      47   3e-05
gi|21264330 mindbomb homolog 2 [Homo sapiens]                          45   8e-05
gi|46852178 potassium channel modulatory factor 1 [Homo sapiens]       44   3e-04
gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sap...    43   4e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   40   0.002
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       40   0.004
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    40   0.004
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             40   0.004
gi|71043932 zinc finger, SWIM domain containing 2 [Homo sapiens]       39   0.005
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        39   0.007
gi|157364926 dystrotelin [Homo sapiens]                                39   0.007
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              39   0.009
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    37   0.021
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         37   0.021
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]      37   0.027
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...    37   0.035
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    37   0.035
gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]                37   0.035
gi|55741849 WD repeat domain 22 [Homo sapiens]                         36   0.046
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   36   0.046
gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]                36   0.046
gi|104526627 triadin [Homo sapiens]                                    36   0.046
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    36   0.060

>gi|214830451 sequestosome 1 isoform 2 [Homo sapiens]
          Length = 356

 Score =  751 bits (1940), Expect = 0.0
 Identities = 356/356 (100%), Positives = 356/356 (100%)

Query: 1   MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 60
           MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV
Sbjct: 1   MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 60

Query: 61  CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 120
           CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG
Sbjct: 61  CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 120

Query: 121 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 180
           NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK
Sbjct: 121 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 180

Query: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240
           RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE
Sbjct: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240

Query: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300
           QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP
Sbjct: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300

Query: 301 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 356
           HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL
Sbjct: 301 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 356


>gi|214830438 sequestosome 1 isoform 2 [Homo sapiens]
          Length = 356

 Score =  751 bits (1940), Expect = 0.0
 Identities = 356/356 (100%), Positives = 356/356 (100%)

Query: 1   MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 60
           MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV
Sbjct: 1   MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 60

Query: 61  CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 120
           CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG
Sbjct: 61  CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 120

Query: 121 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 180
           NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK
Sbjct: 121 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 180

Query: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240
           RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE
Sbjct: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240

Query: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300
           QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP
Sbjct: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300

Query: 301 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 356
           HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL
Sbjct: 301 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 356


>gi|4505571 sequestosome 1 isoform 1 [Homo sapiens]
          Length = 440

 Score =  751 bits (1940), Expect = 0.0
 Identities = 356/356 (100%), Positives = 356/356 (100%)

Query: 1   MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 60
           MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV
Sbjct: 85  MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 144

Query: 61  CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 120
           CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG
Sbjct: 145 CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 204

Query: 121 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 180
           NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK
Sbjct: 205 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 264

Query: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240
           RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE
Sbjct: 265 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 324

Query: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300
           QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP
Sbjct: 325 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 384

Query: 301 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 356
           HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL
Sbjct: 385 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 440


>gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 21  CRRDHRPPCAQEA---PRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEG--KGL 75
           C  +   P ++E    P N    ++ C+ C   +VG RY+CS+CP Y++C  CE    G 
Sbjct: 191 CPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGH 250

Query: 76  HRGHTKLAFPSPFGHLSEGFSHSRW 100
              H  L    P    SE F HS++
Sbjct: 251 DTNHVLLKLRRPVVGSSEPFCHSKY 275


>gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 21  CRRDHRPPCAQEA---PRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEG--KGL 75
           C  +   P ++E    P N    ++ C+ C   +VG RY+CS+CP Y++C  CE    G 
Sbjct: 191 CPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGH 250

Query: 76  HRGHTKLAFPSPFGHLSEGFSHSRW 100
              H  L    P    SE F HS++
Sbjct: 251 DTNHVLLKLRRPVVGSSEPFCHSKY 275


>gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 21  CRRDHRPPCAQEA---PRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEG--KGL 75
           C  +   P ++E    P N    ++ C+ C   +VG RY+CS+CP Y++C  CE    G 
Sbjct: 191 CPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGH 250

Query: 76  HRGHTKLAFPSPFGHLSEGFSHSRW 100
              H  L    P    SE F HS++
Sbjct: 251 DTNHVLLKLRRPVVGSSEPFCHSKY 275


>gi|30348954 mindbomb homolog 1 [Homo sapiens]
          Length = 1006

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 33  APRNMVHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVC-EGKGLHRGHTKLAFPSP 87
           AP  + H   +CD C   P++G R+KC+ C +YDLC+VC  G   H  H      +P
Sbjct: 74  APTGIKHDGTMCDTCRQQPIIGIRWKCAECTNYDLCTVCYHGDKHHLRHRFYRITTP 130


>gi|126032348 hect domain and RLD 2 [Homo sapiens]
          Length = 4834

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 13/82 (15%)

Query: 38   VHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVC-EGKGLHRGHTKLAFPSPFGHLSEGF 95
            +HP V CDGC   P+ G+R+KC  C D+D C  C + K  +  HT       FG ++E  
Sbjct: 2702 IHPGVTCDGCQMFPINGSRFKCRNCDDFDFCETCFKTKKHNTRHT-------FGRINEPG 2754

Query: 96   SHS----RWLRKVKHGHFGWPG 113
              +    R  +++K  H   PG
Sbjct: 2755 QSAVFCGRSGKQLKRCHSSQPG 2776


>gi|21264330 mindbomb homolog 2 [Homo sapiens]
          Length = 1013

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 19/33 (57%), Positives = 23/33 (69%), Gaps = 1/33 (3%)

Query: 39  HPNVICDGCNGPVV-GTRYKCSVCPDYDLCSVC 70
           HPN+ICD C    + G R+KC VC DYDLC+ C
Sbjct: 144 HPNIICDCCKKHGLRGMRWKCRVCLDYDLCTQC 176


>gi|46852178 potassium channel modulatory factor 1 [Homo sapiens]
          Length = 381

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 19/37 (51%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query: 39 HPNVICDGC-NGPVVGTRYKCSVCPDYDLCSVCEGKG 74
          H  V CD C  G   G RYKC +C DYDLC+ C   G
Sbjct: 4  HEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESG 40


>gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sapiens]
          Length = 2961

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 16/34 (47%), Positives = 21/34 (61%)

Query: 37   MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVC 70
            MV+    CD C G ++G R  C+VC D+DLC  C
Sbjct: 1825 MVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGC 1858



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 13/35 (37%), Positives = 21/35 (60%)

Query: 36   NMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVC 70
            ++++ ++ CDGC+      RY+C  C D DLC  C
Sbjct: 1775 DLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTC 1809


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 20/215 (9%)

Query: 118  PPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEH 177
            PP   S   P+AG A PGP   S + P+  P    +        A+   L  E       
Sbjct: 1123 PPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSE 1182

Query: 178  GGKRSRL--TPVSPESSSTEEKSSSQPSSCCSDP----------SKPGGNVEGATQSLAE 225
              K S     P+ P+++   + S   P+    +P          S P  N+E   Q    
Sbjct: 1183 TSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPR 1242

Query: 226  QMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDP 285
                 +L SE   + Q++++  S G  +    S  ++DP   +L    +  S+   S+  
Sbjct: 1243 SRSSHSLPSEASSQPQVKTNGISDGKRE----SPLKIDPFE-DLSFNLLAVSKAQLSV-- 1295

Query: 286  SQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSM 320
             Q  P    +      LP      ++ S+S M +M
Sbjct: 1296 -QTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTM 1329


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 47/197 (23%), Positives = 69/197 (35%), Gaps = 31/197 (15%)

Query: 40  PNVICDGCNGPVVGTRYKCS--------VCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHL 91
           P  IC   NG ++  + +C         V P  + C VC         T     + FG  
Sbjct: 58  PCQICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCS-------QTPGGGNTNFGRG 110

Query: 92  SEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTA------------- 138
            +G      L  V  G  G PG   GPPG+  PR  R  + RPGP               
Sbjct: 111 RKGQKGEPGLVPVVTGIRGRPG-PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQ 169

Query: 139 ESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSS--TEE 196
             A GP   PS      +    +A ++ L  +  +  + G     + PV P        +
Sbjct: 170 PGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQ 229

Query: 197 KSSSQPSSCCSDPSKPG 213
           +  + P+    +P  PG
Sbjct: 230 QGGAGPTGPPGEPGDPG 246


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 50/241 (20%)

Query: 117 GPPGNWSPRPPRAGEARPGP----------------------------TAESASGPSEDP 148
           GPP    P PPRA   RP                              T+ S+S   + P
Sbjct: 271 GPPPP-PPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKP 329

Query: 149 SVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSD 208
           + +     GE V A   P   +  ++VE        +  S  + S+   SSS   S    
Sbjct: 330 AKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDS 389

Query: 209 PSKPGGN-VEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTG 267
             +P  N  +G  +S+ E ++          EE  E D+ SG +      ++ + +P  G
Sbjct: 390 DFEPSQNHSQGPLRSMVEDLQS---------EESDEDDSSSGEE------AAGKTNP--G 432

Query: 268 ELQSLQMPESEGPSSLD---PSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSD 324
               L   +SE  +S D   PS+E P   K       +     P       ++L  G  D
Sbjct: 433 RDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYD 492

Query: 325 E 325
           +
Sbjct: 493 K 493


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 5/78 (6%)

Query: 189 PESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCS 248
           PES S++ +SSS      +D S  G ++  ++ S++ +      E EG  EE+ E +   
Sbjct: 376 PESCSSDSESSSYSDHAAND-SDFGSSLSSSSNSVSSEEE----EEEGEEEEEEEEEEGG 430

Query: 249 GGDDDWTHLSSKEVDPST 266
            G  D + +SS+E D ST
Sbjct: 431 SGASDSSEVSSEEEDSST 448


>gi|71043932 zinc finger, SWIM domain containing 2 [Homo sapiens]
          Length = 633

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 1/63 (1%)

Query: 19  KECRRDHRPPCAQEAPRNMVHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVCEGKGLHR 77
           +E +   +   A E  R   H  + C+ C   P+ G  YKC+ C +Y LC  C     H 
Sbjct: 209 EEFKNSSKLVAAAEKERLDKHLGIPCNNCKQFPIEGKCYKCTECIEYHLCQECFDSCCHL 268

Query: 78  GHT 80
            HT
Sbjct: 269 SHT 271


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 42/168 (25%), Positives = 62/168 (36%), Gaps = 26/168 (15%)

Query: 181  RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALES------ 234
            + R +  S  SSS+   SSS  SS  S       + EG++  +  ++    + S      
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587

Query: 235  ----EGRPEE---------QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPS 281
                EGRP E            S + S      +  SS     S+    S     S   S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647

Query: 282  SLDPSQEGPTGLKEAALYPHLPPEADPRL------IESLSQMLSMGFS 323
            S  P++ GP  L + A  P  PP  + R       I+SL    S+ +S
Sbjct: 2648 SPSPAKPGPQALPKPA-SPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 6/94 (6%)

Query: 133 RPGPTAESASGPSEDPSVNFL---KNVGESVAAALSPLGIE-VDIDVEHGGKRSRLTPVS 188
           RP P+ E +S   E P+   L   ++ G     A +PL  E V+   E    R R  P S
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408

Query: 189 PESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQS 222
           PE       S S P S    P+K   +   + +S
Sbjct: 409 PEKLPQSSSSESSPPS--PQPTKVSRHASSSPES 440


>gi|157364926 dystrotelin [Homo sapiens]
          Length = 578

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)

Query: 27  PPCAQ-EAPRNMVHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVCEGKGLH-RGHTK 81
           P C +  A   + HP   C  C   P+ G RY+C  C ++D+C +C   GLH + H K
Sbjct: 211 PTCHRLSAAERVTHP-ARCTLCRTFPITGLRYRCLKCLNFDICQMCFLSGLHSKSHQK 267


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 26/128 (20%)

Query: 111 WPG--WEMGPPGNWSPRPPRAG-------EARPGPTAESASGPSEDPSVNFLKNVGESVA 161
           W G  W    PG W PRP R G         +PGP  E  + P          + GE VA
Sbjct: 369 WEGYPWGFSEPGVWGPRPCRVGCREVFGRGGQPGPKYEIWTNPLH-------ASQGERVA 421

Query: 162 AALSPLGIEVDIDVE-------HGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGG 214
           A     G+   +           G +R      SP SS+   + S   SSCC  P  P  
Sbjct: 422 AR-KRWGLAQHVRCSGLWGHGTAGRERCSQDSASPASSTGLPEGSEPESSCC--PRTPED 478

Query: 215 NVEGATQS 222
            V+ A+ S
Sbjct: 479 GVDSASPS 486


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 37.4 bits (85), Expect = 0.021
 Identities = 35/152 (23%), Positives = 58/152 (38%), Gaps = 14/152 (9%)

Query: 101  LRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNV---- 156
            L +V+   FG  G E+      +P PP    A P P +     P  +P    L  V    
Sbjct: 957  LEEVEDLEFGTAGGEVE---EGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPG 1013

Query: 157  -----GESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSK 211
                 G   A  L+P  +    +VE  G+     P  P     EE+ S+ P+    +   
Sbjct: 1014 TEEERGADTAPTLAPEALPSQGEVEREGESPAAGP--PPQELVEEEPSAPPTLLEEETED 1071

Query: 212  PGGNVEGATQSLAEQMRKIALESEGRPEEQME 243
                V+   ++ AE+  +   E+E   E++ +
Sbjct: 1072 GSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 37.4 bits (85), Expect = 0.021
 Identities = 51/222 (22%), Positives = 76/222 (34%), Gaps = 27/222 (12%)

Query: 112  PGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEV 171
            PG      GN  P+ P   +A      ES S  S             S +++ S  G E 
Sbjct: 2531 PGLTFEDSGN--PKSPDKAQAEQDGAEESESSSSSSSG-------SSSSSSSSSSSGSET 2581

Query: 172  DIDVEH----------GGKRSRLTP---VSPESSSTEEKSSSQPSSCCSDPSKPGGNVEG 218
            + + E           GG+          SP SSS+   SSS  SS  S  S    +   
Sbjct: 2582 EGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641

Query: 219  ATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEV--DPSTGELQSLQMP- 275
            ++ S +      +  S         S + S  D+D +  S  E    P+ G      +P 
Sbjct: 2642 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPT 2701

Query: 276  -ESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQ 316
              ++      PS   P G K  A  P  PP    + ++  +Q
Sbjct: 2702 KATKQAGKARPSAHSP-GKKTPAPQPQAPPPQPTQPLQPKAQ 2742


>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
          Length = 1992

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 10/111 (9%)

Query: 187 VSPESSSTEEKSSSQPSSCCSDPSKPGGNV-EGATQSLAEQMRKIALESEGRPEEQMESD 245
           ++  SS+    SSS   +  S    PG  V +G  Q+ A + R  +  S  R   + E  
Sbjct: 193 ITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQS 252

Query: 246 NCSGGDD-DWTHLSSKEVD-PSTGELQSLQMPESEGPSSLDPSQEGPTGLK 294
              G    DW    S +V  P T     L +P   G S  + S+ GP+GL+
Sbjct: 253 KTGGSSKFDWAARFSPKVSLPKT----KLSLP---GSSKSETSKPGPSGLQ 296


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
           sapiens]
          Length = 1135

 Score = 36.6 bits (83), Expect = 0.035
 Identities = 58/199 (29%), Positives = 82/199 (41%), Gaps = 47/199 (23%)

Query: 131 EARPGPT-----AESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLT 185
           EA P P      A++  G SED  +  L++VG+S A    P  +     V   GK+  L 
Sbjct: 583 EATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAA----PTFMISPETVTGTGKKCSLP 638

Query: 186 PVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESD 245
             + E S  E+    +P  C S PS+           L+ +   IA   EGRP       
Sbjct: 639 --AEEDSVLEKLGERKP--CNSQPSE-----------LSSETSGIARPEEGRPV------ 677

Query: 246 NCSGGDDDWTHLSSKEVDPS----TGELQSLQMPESE------GPSSLDPSQEGPTGL-- 293
             SG  +D T   +KE+ PS    T  L + Q  ++        P+SL P Q  PT +  
Sbjct: 678 -VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL-PKQPAPTTIGG 735

Query: 294 ---KEAALYPHLPPEADPR 309
              K  +L   L P A P+
Sbjct: 736 LNKKPMSLASGLVPAAPPK 754


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
           sapiens]
          Length = 1152

 Score = 36.6 bits (83), Expect = 0.035
 Identities = 58/199 (29%), Positives = 82/199 (41%), Gaps = 47/199 (23%)

Query: 131 EARPGPT-----AESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLT 185
           EA P P      A++  G SED  +  L++VG+S A    P  +     V   GK+  L 
Sbjct: 583 EATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAA----PTFMISPETVTGTGKKCSLP 638

Query: 186 PVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESD 245
             + E S  E+    +P  C S PS+           L+ +   IA   EGRP       
Sbjct: 639 --AEEDSVLEKLGERKP--CNSQPSE-----------LSSETSGIARPEEGRPV------ 677

Query: 246 NCSGGDDDWTHLSSKEVDPS----TGELQSLQMPESE------GPSSLDPSQEGPTGL-- 293
             SG  +D T   +KE+ PS    T  L + Q  ++        P+SL P Q  PT +  
Sbjct: 678 -VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL-PKQPAPTTIGG 735

Query: 294 ---KEAALYPHLPPEADPR 309
              K  +L   L P A P+
Sbjct: 736 LNKKPMSLASGLVPAAPPK 754


>gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]
          Length = 743

 Score = 36.6 bits (83), Expect = 0.035
 Identities = 73/333 (21%), Positives = 121/333 (36%), Gaps = 44/333 (13%)

Query: 36  NMVHPNVICDGCNGP-VVGTRYKCSVCPDYDLCSVCEGKG--------LHRGHTKLAFPS 86
           N+ HP V C  C+   ++G RY+C  C +Y LC  C  +G         H+     ++ S
Sbjct: 236 NVFHP-VECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKS 294

Query: 87  PFGHLSEGFSHSRWLRKVKHG-HFGWPGWEMGP------PGNWSPRPPRA--------GE 131
           P   L+   S S      +   H  +P     P         W PRP  +          
Sbjct: 295 PAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSV 354

Query: 132 ARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPES 191
              G    + S P +D  V   K +  +  A L   GI+  ++V       RL       
Sbjct: 355 PSSGSPFITRSSPPKDSEVEQNKLLARAAPAFLKGKGIQYSLNV-----ADRLADEHVLI 409

Query: 192 SSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALE-SEGRPEEQMESDNCS-- 248
                   + P SC  + S     ++   + +A    ++A E S  +P +Q  + + S  
Sbjct: 410 GLYVNMLRNNP-SCMLESS---NRLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFT 465

Query: 249 -GGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDP----SQEGPTGLKEAALYPHLP 303
              +     L ++  + +   LQ +Q    E   +  P    +Q+ PT L E  L     
Sbjct: 466 IDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRK 525

Query: 304 PEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK 336
            E + R+         +    EG  L +LL+T+
Sbjct: 526 DELEQRMSALQESRRELMVQLEG--LMKLLKTQ 556


>gi|55741849 WD repeat domain 22 [Homo sapiens]
          Length = 942

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 18/164 (10%)

Query: 134 PGPTAESASGPSEDPSVNFLKNVGESVAAALSPLG------IEVDIDVEHGGKRSRLTPV 187
           P PT E A+  S    ++ L+   +    ALS          EV++D +       L P 
Sbjct: 499 PTPTCEDAA--SRQQRLSALRRYQDKRLLALSNESDSEENVCEVELDTD-------LFP- 548

Query: 188 SPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNC 247
            P S S E++SSS  SS  S+  +       +T       R+     E +P   ++  N 
Sbjct: 549 RPRSPSPEDESSSSSSSSSSEDEEELNERRASTWQRNAMRRRQKTTREDKPSAPIKPTNT 608

Query: 248 SGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPT 291
             G+D++ +   K  D S+    S +   S     + PS+  PT
Sbjct: 609 YIGEDNYDYPQIKVDDLSSSPTSSPE--RSTSTLEIQPSRASPT 650


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 45/206 (21%), Positives = 76/206 (36%), Gaps = 20/206 (9%)

Query: 127  PRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRL-- 184
            P+AG A PGP   S + P+  P    +        A+   L  E         K S    
Sbjct: 1218 PQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLP 1277

Query: 185  TPVSPESSSTEEKSSSQPSSCCSDP----------SKPGGNVEGATQSLAEQMRKIALES 234
             P+ P+++   + S   P+    +P          S P  N+E   Q         +L S
Sbjct: 1278 EPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPS 1337

Query: 235  EGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLK 294
            E   + Q++++  S G  +    S  ++DP   +L    +  S+   S+   Q  P    
Sbjct: 1338 EASSQPQVKTNGISDGKRE----SPLKIDPFE-DLSFNLLAVSKAQLSV---QTSPVPTP 1389

Query: 295  EAALYPHLPPEADPRLIESLSQMLSM 320
            +      LP      ++ S+S M +M
Sbjct: 1390 DPKRLIQLPSATQSNVLSSVSCMPTM 1415


>gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]
          Length = 570

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 40/164 (24%), Positives = 61/164 (37%), Gaps = 25/164 (15%)

Query: 36  NMVHPNVICDGCNGP-VVGTRYKCSVCPDYDLCSVCEGKG--------LHRGHTKLAFPS 86
           N+ HP V C  C+   ++G RY+C  C +Y LC  C  +G         H+     ++ S
Sbjct: 236 NVFHP-VECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKS 294

Query: 87  PFGHLSEGFSHSRWLRKVKHG-HFGWPGWEMGP------PGNWSPRPPRA--------GE 131
           P   L+   S S      +   H  +P     P         W PRP  +          
Sbjct: 295 PAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSV 354

Query: 132 ARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDV 175
              G    + S P +D  V   K +  +  A L   GI+  ++V
Sbjct: 355 PSSGSPFITRSSPPKDSEVEQNKLLARAAPAFLKGKGIQYSLNV 398


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 36/194 (18%), Positives = 73/194 (37%), Gaps = 12/194 (6%)

Query: 126 PPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEH-----GGK 180
           P +A E + G    +A   ++           +  A    P G + +   +H       K
Sbjct: 352 PGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPK 411

Query: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240
           +    P   +  +  E++  +  +     + PG   E  T+++ +++RK   E  G+   
Sbjct: 412 KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRK---EKSGKTSS 468

Query: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300
            ++      G ++    S KE +P T + + +    S+    + P      G KE    P
Sbjct: 469 ILKDKEPIKGKEEKVPASLKEKEPETKKDEKM----SKAGKEVKPKPPQLQGKKEEKPEP 524

Query: 301 HLPPEADPRLIESL 314
            +  EA P + E +
Sbjct: 525 QIKKEAKPAISEKV 538


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
          Length = 2524

 Score = 35.8 bits (81), Expect = 0.060
 Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 17/174 (9%)

Query: 144  PSEDPSVNF-------LKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEE 196
            P+ DP  N        LK + +  AAA+ P+  +V     H   R    P  P   +   
Sbjct: 947  PTGDPRANASPQKPLDLKQLKQR-AAAIPPIVTKV-----HEPPREDAAPTKPAPPAPPP 1000

Query: 197  KSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTH 256
              + QP S    P +PG +  G ++S A    K A +    P    E+    G    WT 
Sbjct: 1001 PQNLQPES--DAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTS 1058

Query: 257  LSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAA--LYPHLPPEADP 308
                 V P      S   P+    S   P    P GL + A  + P  P  ++P
Sbjct: 1059 GLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNP 1112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,887,913
Number of Sequences: 37866
Number of extensions: 1073242
Number of successful extensions: 5584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 320
Number of HSP's that attempted gapping in prelim test: 5061
Number of HSP's gapped (non-prelim): 725
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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