Search of human proteins with 21450675

Search of human proteins with 21450675

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21450675 RNA binding motif protein 46 [Homo sapiens]
         (533 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21450675 RNA binding motif protein 46 [Homo sapiens]              1091   0.0  
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]    465   e-131
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]    465   e-131
gi|20357575 apobec-1 complementation factor isoform 2 [Homo sapi...   464   e-131
gi|20357572 apobec-1 complementation factor isoform 1 [Homo sapi...   464   e-131
gi|20357578 apobec-1 complementation factor isoform 3 [Homo sapi...   438   e-123
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4...   345   8e-95
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [...   345   8e-95
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3...   339   3e-93
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1...   339   3e-93
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ...   333   2e-91
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ...   333   2e-91
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ...   333   2e-91
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ...   333   2e-91
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ...   282   5e-76
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ...   282   5e-76
gi|34740339 dead end homolog 1 [Homo sapiens]                         189   4e-48
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa...    78   2e-14
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    75   2e-13
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]           74   4e-13
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s...    71   2e-12
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]      71   3e-12
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...    70   6e-12
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...    70   6e-12
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...    70   6e-12
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s...    67   3e-11
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s...    67   4e-11
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa...    67   4e-11
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]      67   5e-11
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s...    63   6e-10

>gi|21450675 RNA binding motif protein 46 [Homo sapiens]
          Length = 533

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 533/533 (100%), Positives = 533/533 (100%)

Query: 1   MNEENIDGTNGCSKVRTGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRG 60
           MNEENIDGTNGCSKVRTGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRG
Sbjct: 1   MNEENIDGTNGCSKVRTGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRG 60

Query: 61  CEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRI 120
           CEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRI
Sbjct: 61  CEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRI 120

Query: 121 LNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDK 180
           LNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDK
Sbjct: 121 LNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDK 180

Query: 181 TKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYV 240
           TKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYV
Sbjct: 181 TKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYV 240

Query: 241 RNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGAS 300
           RNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGAS
Sbjct: 241 RNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGAS 300

Query: 301 IEVTLAKPVNKENTWRQHLNGQISPNSENLIVFANKEESHPKTLGKLPTLPARLNGQHSP 360
           IEVTLAKPVNKENTWRQHLNGQISPNSENLIVFANKEESHPKTLGKLPTLPARLNGQHSP
Sbjct: 301 IEVTLAKPVNKENTWRQHLNGQISPNSENLIVFANKEESHPKTLGKLPTLPARLNGQHSP 360

Query: 361 SPPEVERCTYPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQ 420
           SPPEVERCTYPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQ
Sbjct: 361 SPPEVERCTYPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQ 420

Query: 421 DGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFHRSSINSLS 480
           DGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFHRSSINSLS
Sbjct: 421 DGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFHRSSINSLS 480

Query: 481 PVSATLSSGTPSVLPYTSRPYSYPGYPLSPTISLANGSHVGQRLCISNQASFF 533
           PVSATLSSGTPSVLPYTSRPYSYPGYPLSPTISLANGSHVGQRLCISNQASFF
Sbjct: 481 PVSATLSSGTPSVLPYTSRPYSYPGYPLSPTISLANGSHVGQRLCISNQASFF 533


>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
          Length = 593

 Score =  465 bits (1196), Expect = e-131
 Identities = 222/295 (75%), Positives = 255/295 (86%)

Query: 18  GIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDEL 77
           G  NEAALLALME+TGY+MVQENGQRK+GGPPPGWEGP P RGCEVFVGKIPRD+YEDEL
Sbjct: 28  GAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDEL 87

Query: 78  VPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           VPVFE  G+IYE RLMM+F G+NRGYAFVMY  K EA+ A+R LNNYEIRPG+ +GVC S
Sbjct: 88  VPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCS 147

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           +DNCRLFIG IPK KK+EEIL+E+ KVTEGV+DVIVY SA DK KNRGFAFVEYESHRAA
Sbjct: 148 VDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAA 207

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           AMARRKL+PG  QLWGH I VDWA+PE +VDE+ M+ VK+LYVRNLMI TTE+TIK  F 
Sbjct: 208 AMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFG 267

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKE 312
           +F PG VERVKK+RDYAFVHF +REDAV AM+ +NG  ++G+ +EVTLAKPV+KE
Sbjct: 268 QFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKE 322


>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
          Length = 524

 Score =  465 bits (1196), Expect = e-131
 Identities = 222/295 (75%), Positives = 255/295 (86%)

Query: 18  GIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDEL 77
           G  NEAALLALME+TGY+MVQENGQRK+GGPPPGWEGP P RGCEVFVGKIPRD+YEDEL
Sbjct: 28  GAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDEL 87

Query: 78  VPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           VPVFE  G+IYE RLMM+F G+NRGYAFVMY  K EA+ A+R LNNYEIRPG+ +GVC S
Sbjct: 88  VPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCS 147

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           +DNCRLFIG IPK KK+EEIL+E+ KVTEGV+DVIVY SA DK KNRGFAFVEYESHRAA
Sbjct: 148 VDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAA 207

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           AMARRKL+PG  QLWGH I VDWA+PE +VDE+ M+ VK+LYVRNLMI TTE+TIK  F 
Sbjct: 208 AMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFG 267

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKE 312
           +F PG VERVKK+RDYAFVHF +REDAV AM+ +NG  ++G+ +EVTLAKPV+KE
Sbjct: 268 QFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKE 322


>gi|20357575 apobec-1 complementation factor isoform 2 [Homo
           sapiens]
          Length = 594

 Score =  464 bits (1195), Expect = e-131
 Identities = 216/297 (72%), Positives = 258/297 (86%)

Query: 17  TGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDE 76
           +G Q EAAL AL+++TGY++VQENGQRK+GGPPPGW+  PP RGCE+F+GK+PRD++EDE
Sbjct: 12  SGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDE 71

Query: 77  LVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCV 136
           L+P+ E+ GKIYE R+MM+F+G NRGYAFV ++ K EA+ AI+ LNNYEIR G+ +GVC 
Sbjct: 72  LIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCA 131

Query: 137 SLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRA 196
           S+DNCRLF+G IPK KK+EEIL EMKKVTEGVVDVIVYPSA DKTKNRGFAFVEYESHRA
Sbjct: 132 SVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRA 191

Query: 197 AAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEF 256
           AAMARRKL+PG  QLWGH I VDWA+PE EVDE+TM  VK+LYVRNLM+ST+EE I+ EF
Sbjct: 192 AAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEF 251

Query: 257 NKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKEN 313
           N  KPGAVERVKK+RDYAFVHF NREDAV AM  +NGK +DG+ IEVTLAKPV+K++
Sbjct: 252 NNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDS 308



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)

Query: 370 YPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYK 429
           Y   PG +LTP++  +LK      A   L+  C KNNW  P Y L+S   QD + L +YK
Sbjct: 423 YDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYK 482

Query: 430 IVIPAIANGSQSY--FMPDKLCTTLEDAKELAAQFTL 464
           I IPA+A+ + +   F P KL   +++AK  AA++TL
Sbjct: 483 ITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTL 519


>gi|20357572 apobec-1 complementation factor isoform 1 [Homo
           sapiens]
          Length = 586

 Score =  464 bits (1195), Expect = e-131
 Identities = 216/297 (72%), Positives = 258/297 (86%)

Query: 17  TGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDE 76
           +G Q EAAL AL+++TGY++VQENGQRK+GGPPPGW+  PP RGCE+F+GK+PRD++EDE
Sbjct: 12  SGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDE 71

Query: 77  LVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCV 136
           L+P+ E+ GKIYE R+MM+F+G NRGYAFV ++ K EA+ AI+ LNNYEIR G+ +GVC 
Sbjct: 72  LIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCA 131

Query: 137 SLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRA 196
           S+DNCRLF+G IPK KK+EEIL EMKKVTEGVVDVIVYPSA DKTKNRGFAFVEYESHRA
Sbjct: 132 SVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRA 191

Query: 197 AAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEF 256
           AAMARRKL+PG  QLWGH I VDWA+PE EVDE+TM  VK+LYVRNLM+ST+EE I+ EF
Sbjct: 192 AAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEF 251

Query: 257 NKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKEN 313
           N  KPGAVERVKK+RDYAFVHF NREDAV AM  +NGK +DG+ IEVTLAKPV+K++
Sbjct: 252 NNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDS 308



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)

Query: 370 YPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYK 429
           Y   PG +LTP++  +LK      A   L+  C KNNW  P Y L+S   QD + L +YK
Sbjct: 415 YDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYK 474

Query: 430 IVIPAIANGSQSY--FMPDKLCTTLEDAKELAAQFTL 464
           I IPA+A+ + +   F P KL   +++AK  AA++TL
Sbjct: 475 ITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTL 511


>gi|20357578 apobec-1 complementation factor isoform 3 [Homo
           sapiens]
          Length = 594

 Score =  438 bits (1127), Expect = e-123
 Identities = 203/276 (73%), Positives = 240/276 (86%)

Query: 38  QENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFS 97
           +ENGQRK+GGPPPGW+  PP RGCE+F+GK+PRD++EDEL+P+ E+ GKIYE R+MM+F+
Sbjct: 41  KENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFN 100

Query: 98  GENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEI 157
           G NRGYAFV ++ K EA+ AI+ LNNYEIR G+ +GVC S+DNCRLF+G IPK KK+EEI
Sbjct: 101 GNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEI 160

Query: 158 LDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQ 217
           L EMKKVTEGVVDVIVYPSA DKTKNRGFAFVEYESHRAAAMARRKL+PG  QLWGH I 
Sbjct: 161 LSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIA 220

Query: 218 VDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVH 277
           VDWA+PE EVDE+TM  VK+LYVRNLM+ST+EE I+ EFN  KPGAVERVKK+RDYAFVH
Sbjct: 221 VDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVH 280

Query: 278 FFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKEN 313
           F NREDAV AM  +NGK +DG+ IEVTLAKPV+K++
Sbjct: 281 FSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDS 316



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)

Query: 370 YPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYK 429
           Y   PG +LTP++  +LK      A   L+  C KNNW  P Y L+S   QD + L +YK
Sbjct: 423 YDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYK 482

Query: 430 IVIPAIANGSQSY--FMPDKLCTTLEDAKELAAQFTL 464
           I IPA+A+ + +   F P KL   +++AK  AA++TL
Sbjct: 483 ITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTL 519


>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
           [Homo sapiens]
          Length = 532

 Score =  345 bits (884), Expect = 8e-95
 Identities = 171/300 (57%), Positives = 225/300 (75%), Gaps = 5/300 (1%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G EVFVGKIPRD+YEDELV
Sbjct: 22  DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELV 81

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  SG+NRGYAF+ +  KE AQ A+++ ++YEIRPGK +GVC+S
Sbjct: 82  PLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCIS 141

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE IL+E  KVTEG+VDVI+Y    DK KNRGF F+EYE H++A
Sbjct: 142 VANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSA 201

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A ARR+L+ G  ++WG+ + V+WADP +E D E M +VKVL+VRNL  + TEE ++  F+
Sbjct: 202 AQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFS 261

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAFVHF +R  AV AM  MNGK I+G  IE+ LAKP +K+   RQ
Sbjct: 262 EF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQ 319


>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
           [Homo sapiens]
          Length = 633

 Score =  345 bits (884), Expect = 8e-95
 Identities = 171/300 (57%), Positives = 225/300 (75%), Gaps = 5/300 (1%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G EVFVGKIPRD+YEDELV
Sbjct: 123 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELV 182

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  SG+NRGYAF+ +  KE AQ A+++ ++YEIRPGK +GVC+S
Sbjct: 183 PLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCIS 242

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE IL+E  KVTEG+VDVI+Y    DK KNRGF F+EYE H++A
Sbjct: 243 VANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSA 302

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A ARR+L+ G  ++WG+ + V+WADP +E D E M +VKVL+VRNL  + TEE ++  F+
Sbjct: 303 AQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFS 362

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAFVHF +R  AV AM  MNGK I+G  IE+ LAKP +K+   RQ
Sbjct: 363 EF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQ 420


>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
           [Homo sapiens]
          Length = 535

 Score =  339 bits (870), Expect = 3e-93
 Identities = 171/303 (56%), Positives = 225/303 (74%), Gaps = 8/303 (2%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G EVFVGKIPRD+YEDELV
Sbjct: 22  DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELV 81

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  SG+NRGYAF+ +  KE AQ A+++ ++YEIRPGK +GVC+S
Sbjct: 82  PLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCIS 141

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVT---EGVVDVIVYPSATDKTKNRGFAFVEYESH 194
           + N RLF+G+IPK K KE IL+E  KVT   EG+VDVI+Y    DK KNRGF F+EYE H
Sbjct: 142 VANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDH 201

Query: 195 RAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKA 254
           ++AA ARR+L+ G  ++WG+ + V+WADP +E D E M +VKVL+VRNL  + TEE ++ 
Sbjct: 202 KSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEK 261

Query: 255 EFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENT 314
            F++F  G +ERVKKL+DYAFVHF +R  AV AM  MNGK I+G  IE+ LAKP +K+  
Sbjct: 262 SFSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRK 319

Query: 315 WRQ 317
            RQ
Sbjct: 320 ERQ 322


>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
           [Homo sapiens]
          Length = 636

 Score =  339 bits (870), Expect = 3e-93
 Identities = 171/303 (56%), Positives = 225/303 (74%), Gaps = 8/303 (2%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G EVFVGKIPRD+YEDELV
Sbjct: 123 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELV 182

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  SG+NRGYAF+ +  KE AQ A+++ ++YEIRPGK +GVC+S
Sbjct: 183 PLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCIS 242

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVT---EGVVDVIVYPSATDKTKNRGFAFVEYESH 194
           + N RLF+G+IPK K KE IL+E  KVT   EG+VDVI+Y    DK KNRGF F+EYE H
Sbjct: 243 VANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDH 302

Query: 195 RAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKA 254
           ++AA ARR+L+ G  ++WG+ + V+WADP +E D E M +VKVL+VRNL  + TEE ++ 
Sbjct: 303 KSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEK 362

Query: 255 EFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENT 314
            F++F  G +ERVKKL+DYAFVHF +R  AV AM  MNGK I+G  IE+ LAKP +K+  
Sbjct: 363 SFSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRK 420

Query: 315 WRQ 317
            RQ
Sbjct: 421 ERQ 423


>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 6 [Homo sapiens]
          Length = 562

 Score =  333 bits (854), Expect = 2e-91
 Identities = 164/300 (54%), Positives = 222/300 (74%), Gaps = 5/300 (1%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G E+FVGKIPRD++EDELV
Sbjct: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE+IL+E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ A
Sbjct: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A ARR+L+ G  ++WG+   V+WADP ++ D E M +VKVL+VRNL  + TEE ++  F+
Sbjct: 300 AQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFS 359

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAF+HF  R+ AV AM  MNGK ++G +IE+  AKP +++   R+
Sbjct: 360 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 417


>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 2 [Homo sapiens]
          Length = 464

 Score =  333 bits (854), Expect = 2e-91
 Identities = 164/300 (54%), Positives = 222/300 (74%), Gaps = 5/300 (1%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G E+FVGKIPRD++EDELV
Sbjct: 22  DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 81

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 82  PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 141

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE+IL+E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ A
Sbjct: 142 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 201

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A ARR+L+ G  ++WG+   V+WADP ++ D E M +VKVL+VRNL  + TEE ++  F+
Sbjct: 202 AQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFS 261

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAF+HF  R+ AV AM  MNGK ++G +IE+  AKP +++   R+
Sbjct: 262 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 319


>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 5 [Homo sapiens]
          Length = 561

 Score =  333 bits (854), Expect = 2e-91
 Identities = 164/300 (54%), Positives = 222/300 (74%), Gaps = 5/300 (1%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G E+FVGKIPRD++EDELV
Sbjct: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE+IL+E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ A
Sbjct: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A ARR+L+ G  ++WG+   V+WADP ++ D E M +VKVL+VRNL  + TEE ++  F+
Sbjct: 300 AQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFS 359

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAF+HF  R+ AV AM  MNGK ++G +IE+  AKP +++   R+
Sbjct: 360 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 417


>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 1 [Homo sapiens]
          Length = 623

 Score =  333 bits (854), Expect = 2e-91
 Identities = 164/300 (54%), Positives = 222/300 (74%), Gaps = 5/300 (1%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G E+FVGKIPRD++EDELV
Sbjct: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE+IL+E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ A
Sbjct: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A ARR+L+ G  ++WG+   V+WADP ++ D E M +VKVL+VRNL  + TEE ++  F+
Sbjct: 300 AQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFS 359

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAF+HF  R+ AV AM  MNGK ++G +IE+  AKP +++   R+
Sbjct: 360 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 417


>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 3 [Homo sapiens]
          Length = 527

 Score =  282 bits (722), Expect = 5e-76
 Identities = 149/300 (49%), Positives = 199/300 (66%), Gaps = 40/300 (13%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G E+FVGKIPRD++EDELV
Sbjct: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE+IL+E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ A
Sbjct: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A                                   +VKVL+VRNL  + TEE ++  F+
Sbjct: 300 A-----------------------------------QVKVLFVRNLANTVTEEILEKAFS 324

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAF+HF  R+ AV AM  MNGK ++G +IE+  AKP +++   R+
Sbjct: 325 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 382


>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 4 [Homo sapiens]
          Length = 588

 Score =  282 bits (722), Expect = 5e-76
 Identities = 149/300 (49%), Positives = 199/300 (66%), Gaps = 40/300 (13%)

Query: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G E+FVGKIPRD++EDELV
Sbjct: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179

Query: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
           P+FE+AG I++ RLMM+  +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239

Query: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
           + N RLF+G+IPK K KE+IL+E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ A
Sbjct: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299

Query: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
           A                                   +VKVL+VRNL  + TEE ++  F+
Sbjct: 300 A-----------------------------------QVKVLFVRNLANTVTEEILEKAFS 324

Query: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317
           +F  G +ERVKKL+DYAF+HF  R+ AV AM  MNGK ++G +IE+  AKP +++   R+
Sbjct: 325 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 382


>gi|34740339 dead end homolog 1 [Homo sapiens]
          Length = 353

 Score =  189 bits (481), Expect = 4e-48
 Identities = 89/209 (42%), Positives = 135/209 (64%), Gaps = 2/209 (0%)

Query: 16  RTGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYED 75
           R   +N+AAL A + +TG  +VQ NGQRK+GGPPPGW G PPP G EVF+G++P+D+YE 
Sbjct: 13  RVNPENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEH 72

Query: 76  ELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVC 135
           +L+P+F+R G++YEFRLMM FSG NRG+A+  Y+++  AQ AI  L+N+ +RP   + VC
Sbjct: 73  QLIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVC 132

Query: 136 VSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHR 195
            S + C L +  +P    +  +L  ++ +  G+ +  + PS          A +++ SHR
Sbjct: 133 RSTEKCELSVDGLPPNLTRSALLLALQPLGPGLQEARLLPSPGPAPGQ--IALLKFSSHR 190

Query: 196 AAAMARRKLIPGTFQLWGHTIQVDWADPE 224
           AAAMA++ L+ G   L G  + V+W  P+
Sbjct: 191 AAAMAKKALVEGQSHLCGEQVAVEWLKPD 219


>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 485

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 61/211 (28%), Positives = 105/211 (49%), Gaps = 31/211 (14%)

Query: 49  PPGWEGPPPPRG----------CEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMME-FS 97
           P G  GP PP G           ++FVG+IPR + E +L P+FE+ G+IYE  ++ + ++
Sbjct: 23  PVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYT 82

Query: 98  GENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNC--------RLFIGAIP 149
           G ++G AF+ Y  ++ A  A   L+  +  PG    + V   +         +LF+G + 
Sbjct: 83  GMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLN 142

Query: 150 KEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKL----- 204
           K++ +E++L   +    GV+D        D + ++G AFV++ SH  A  A   L     
Sbjct: 143 KQQSEEDVLRLFQPF--GVIDECTVLRGPDGS-SKGCAFVKFSSHTEAQAAIHALHGSQT 199

Query: 205 IPGTFQLWGHTIQVDWADPEKEVDEETMQRV 235
           +PG       ++ V +AD +KE     MQ++
Sbjct: 200 MPGA----SSSLVVKFADTDKERTLRRMQQM 226


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 70/284 (24%), Positives = 123/284 (43%), Gaps = 54/284 (19%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILN 122
           VF+  + + +    L   F   GKI   ++M +  G ++GYAFV +  +  A  AI  +N
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMN 158

Query: 123 NYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEIL---------------------DEM 161
                 GK       L  C++F+G     K +E  L                     + +
Sbjct: 159 ------GKL------LKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERL 206

Query: 162 KKVTEGVVDVIVYPSATDKT-KNRGFAFVEYESHRAAAMARRKL----IPGTFQLWGHTI 216
           K V       +     TD + K++GF FV ++SH AA  A  ++    I G     G   
Sbjct: 207 KDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQ 266

Query: 217 QVDWADPEKEVDEETMQRVKV-------LYVRNLMISTTEETIKAEFNKFKPGAVERVKK 269
           +      E +   E ++R ++       LY++NL  +  +E ++ EF+ F  G++ RVK 
Sbjct: 267 KKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSF--GSISRVKV 324

Query: 270 LRD------YAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAK 307
           +++      +  + F + EDA  AM+ MNG+ +    + + LA+
Sbjct: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 15/129 (11%)

Query: 182 KNRGFAFVEYESHRAAAMARRKLIPGTFQLW-GHTIQVDWADPEKEVDEETMQRVKVLYV 240
           ++ G+A+V +      A A++ L    F +  G +I++ W+  +  +    +  V   ++
Sbjct: 49  RSLGYAYVNFLQ---LADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNV---FI 102

Query: 241 RNLMISTTEETIKAEFNKFKPGAVERVKKLRD------YAFVHFFNREDAVAAMSVMNGK 294
           +NL  S   +T+   F+ F  G +   K + D      YAFVHF N+  A  A+  MNGK
Sbjct: 103 KNLDKSIDNKTLYEHFSAF--GKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGK 160

Query: 295 CIDGASIEV 303
            + G  + V
Sbjct: 161 LLKGCKVFV 169


>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
          Length = 465

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 56/193 (29%), Positives = 101/193 (52%), Gaps = 24/193 (12%)

Query: 58  PRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQL 116
           P   ++FVG+IPR + E +L P+FE+ G+I+E  ++ + ++G ++G AF+ Y  ++ A  
Sbjct: 4   PDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALK 63

Query: 117 AIRILNNYEIRPGKFIGVCVSL-------DNCRLFIGAIPKEKKKEEILDEMKKVTE--G 167
           A   L+  +  PG    + V         ++ +LF+G + K++  E++    +K+ E  G
Sbjct: 64  AQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDV----RKMFEPFG 119

Query: 168 VVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKL-----IPGTFQLWGHTIQVDWAD 222
            +D        D T ++G AFV++++H  A  A   L     +PG       ++ V +AD
Sbjct: 120 TIDECTVLRGPDGT-SKGCAFVKFQTHAEAQAAINTLHSSRTLPGA----SSSLVVKFAD 174

Query: 223 PEKEVDEETMQRV 235
            EKE     MQ+V
Sbjct: 175 TEKERGLRRMQQV 187



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 16/70 (22%), Positives = 40/70 (57%), Gaps = 1/70 (1%)

Query: 58  PRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQL 116
           P GC +F+  +P++  + E++ +F   G +   ++ ++  + +++ + FV +     AQ 
Sbjct: 377 PDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQA 436

Query: 117 AIRILNNYEI 126
           AI+ +N ++I
Sbjct: 437 AIQAMNGFQI 446


>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
           sapiens]
          Length = 448

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 55/186 (29%), Positives = 101/186 (54%), Gaps = 18/186 (9%)

Query: 62  EVFVGKIPRDMYEDELVPVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRI 120
           ++F+G+IPR++ E +L P+FE  GKIYE  ++ + F+G ++G AF+ Y  +E A  A   
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 121 LNNYEIRPGKFIGVCVSL-------DNCRLFIGAIPKEKKKEEILDEMKKVTE--GVVDV 171
           L+  +  PG    + V         ++ +LF+G + K++ +    D+++++ E  G ++ 
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSE----DDVRRLFEAFGNIEE 170

Query: 172 IVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWG--HTIQVDWADPEKEVDE 229
                  D   ++G AFV+Y SH A A A    + G+  + G   ++ V +AD +KE   
Sbjct: 171 CTILRGPD-GNSKGCAFVKYSSH-AEAQAAINALHGSQTMPGASSSLVVKFADTDKERTM 228

Query: 230 ETMQRV 235
             MQ++
Sbjct: 229 RRMQQM 234


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 66/262 (25%), Positives = 117/262 (44%), Gaps = 24/262 (9%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEF-SGENRGYAFVMYTTKEEAQLAIRIL 121
           ++VG +  D+ E  L   F  AG I   R+  +  +  +  YA+V +   ++A+ A+  +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72

Query: 122 NNYEIRPGKFIGVCVSLDNCRL--------FIGAIPKEKKKEEILDEMKKVTEGVVDVIV 173
           N +++  GK + +  S  +  L        F+  + K    + + D +        +++ 
Sbjct: 73  N-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFG----NILS 127

Query: 174 YPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQ 233
                D+  ++G+ FV +E+H AA  A +K+      L G  + V      KE + E   
Sbjct: 128 CNVVCDENGSKGYGFVHFETHEAAERAIKKM--NGMLLNGRKVFVGQFKSRKEREAELGA 185

Query: 234 RVKV---LYVRNLMISTTEETIKAEFNKFKPGAVERVK-----KLRDYAFVHFFNREDAV 285
           R K    +Y++N      +E +K  F KF P    +V      K + + FV F   EDA 
Sbjct: 186 RAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQ 245

Query: 286 AAMSVMNGKCIDGASIEVTLAK 307
            A+  MNGK ++G  I V  A+
Sbjct: 246 KAVDEMNGKELNGKQIYVGRAQ 267



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 70/274 (25%), Positives = 116/274 (42%), Gaps = 34/274 (12%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILN 122
           +FV  + + +    L       G I    ++ + +G ++GY FV + T E A+ AI+ +N
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-SKGYGFVHFETHEAAERAIKKMN 159

Query: 123 NYEIRPGK-FIGVCVSLDNCRLFIGAIPKEKKK-------EEILDEMKKVTEGVVD--VI 172
              +   K F+G   S       +GA  KE          E++ DE  K   G     + 
Sbjct: 160 GMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALS 219

Query: 173 VYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEE-- 230
           V     +  K++GF FV +E H  A  A  ++     +L G  I V  A  + E   E  
Sbjct: 220 VKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGRAQKKVERQTELK 277

Query: 231 -----------TMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRD------Y 273
                      T  +V  LYV+NL     +E ++  F+ F  G +   K + +      +
Sbjct: 278 RTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPF--GTITSAKVMMEGGRSKGF 335

Query: 274 AFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAK 307
            FV F + E+A  A++ MNG+ +    + V LA+
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 73/289 (25%), Positives = 127/289 (43%), Gaps = 37/289 (12%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILN 122
           VF+  + + +    L   F   G I   +++ + +G ++GYAFV + T+E A  AI  +N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159

Query: 123 NYEIRPGK-FIGVCVSLDNCRLFIGAIPKEKKK-------EEILDEMKK--VTEGVVDVI 172
              +   K F+G   S       +GA  KE          EE+ DE  K   ++    + 
Sbjct: 160 GMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLS 219

Query: 173 VYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETM 232
           V        K++GF FV YE H  A  A  ++     ++ G  I V  A  + E   E  
Sbjct: 220 VKVMRDPNGKSKGFGFVSYEKHEDANKAVEEM--NGKEISGKIIFVGRAQKKVERQAELK 277

Query: 233 QRVKVL-------------YVRNLMISTTEETIKAEFNKFKPGAVERVKKL------RDY 273
           ++ + L             Y++NL  +  +E ++ EF+ F  G++   K +      + +
Sbjct: 278 RKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKVMLEDGRSKGF 335

Query: 274 AFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQ 322
            FV F + E+A  A++ MNG+ +    + V LA+   ++   + HL  Q
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ---RKEERKAHLTNQ 381



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 28/264 (10%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEF-SGENRGYAFVMYTTKEEAQLAIRIL 121
           ++VG +  D+ E  L   F  AG +   R+  +  +  + GYA+V +    +A+ A+  +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 122 NNYEIRPGKFIGVCVSLDNCRL--------FIGAIPKEKKKEEILDEMKKVTEGVVDVIV 173
           N +++  GK I +  S  +  L        FI  + K    + + D          +++ 
Sbjct: 73  N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFG----NILS 127

Query: 174 YPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQ 233
                D+  ++G+AFV +E+  AA  A  K+      L    + V      KE + E   
Sbjct: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKM--NGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 234 RVKV---LYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRD-------YAFVHFFNRED 283
           + K    +Y++N      +E++K  F++F  G    VK +RD       + FV +   ED
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHED 243

Query: 284 AVAAMSVMNGKCIDGASIEVTLAK 307
           A  A+  MNGK I G  I V  A+
Sbjct: 244 ANKAVEEMNGKEISGKIIFVGRAQ 267


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 73/289 (25%), Positives = 127/289 (43%), Gaps = 37/289 (12%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILN 122
           VF+  + + +    L   F   G I   +++ + +G ++GYAFV + T+E A  AI  +N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159

Query: 123 NYEIRPGK-FIGVCVSLDNCRLFIGAIPKEKKK-------EEILDEMKK--VTEGVVDVI 172
              +   K F+G   S       +GA  KE          EE+ DE  K   ++    + 
Sbjct: 160 GMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLS 219

Query: 173 VYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETM 232
           V        K++GF FV YE H  A  A  ++     ++ G  I V  A  + E   E  
Sbjct: 220 VKVMRDPNGKSKGFGFVSYEKHEDANKAVEEM--NGKEISGKIIFVGRAQKKVERQAELK 277

Query: 233 QRVKVL-------------YVRNLMISTTEETIKAEFNKFKPGAVERVKKL------RDY 273
           ++ + L             Y++NL  +  +E ++ EF+ F  G++   K +      + +
Sbjct: 278 RKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKVMLEDGRSKGF 335

Query: 274 AFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQ 322
            FV F + E+A  A++ MNG+ +    + V LA+   ++   + HL  Q
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ---RKEERKAHLTNQ 381



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 28/264 (10%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEF-SGENRGYAFVMYTTKEEAQLAIRIL 121
           ++VG +  D+ E  L   F  AG +   R+  +  +  + GYA+V +    +A+ A+  +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 122 NNYEIRPGKFIGVCVSLDNCRL--------FIGAIPKEKKKEEILDEMKKVTEGVVDVIV 173
           N +++  GK I +  S  +  L        FI  + K    + + D          +++ 
Sbjct: 73  N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFG----NILS 127

Query: 174 YPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQ 233
                D+  ++G+AFV +E+  AA  A  K+      L    + V      KE + E   
Sbjct: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKM--NGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 234 RVKV---LYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRD-------YAFVHFFNRED 283
           + K    +Y++N      +E++K  F++F  G    VK +RD       + FV +   ED
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHED 243

Query: 284 AVAAMSVMNGKCIDGASIEVTLAK 307
           A  A+  MNGK I G  I V  A+
Sbjct: 244 ANKAVEEMNGKEISGKIIFVGRAQ 267


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 73/289 (25%), Positives = 127/289 (43%), Gaps = 37/289 (12%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILN 122
           VF+  + + +    L   F   G I   +++ + +G ++GYAFV + T+E A  AI  +N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159

Query: 123 NYEIRPGK-FIGVCVSLDNCRLFIGAIPKEKKK-------EEILDEMKK--VTEGVVDVI 172
              +   K F+G   S       +GA  KE          EE+ DE  K   ++    + 
Sbjct: 160 GMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLS 219

Query: 173 VYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETM 232
           V        K++GF FV YE H  A  A  ++     ++ G  I V  A  + E   E  
Sbjct: 220 VKVMRDPNGKSKGFGFVSYEKHEDANKAVEEM--NGKEISGKIIFVGRAQKKVERQAELK 277

Query: 233 QRVKVL-------------YVRNLMISTTEETIKAEFNKFKPGAVERVKKL------RDY 273
           ++ + L             Y++NL  +  +E ++ EF+ F  G++   K +      + +
Sbjct: 278 RKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKVMLEDGRSKGF 335

Query: 274 AFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQ 322
            FV F + E+A  A++ MNG+ +    + V LA+   ++   + HL  Q
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ---RKEERKAHLTNQ 381



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 28/264 (10%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEF-SGENRGYAFVMYTTKEEAQLAIRIL 121
           ++VG +  D+ E  L   F  AG +   R+  +  +  + GYA+V +    +A+ A+  +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 122 NNYEIRPGKFIGVCVSLDNCRL--------FIGAIPKEKKKEEILDEMKKVTEGVVDVIV 173
           N +++  GK I +  S  +  L        FI  + K    + + D          +++ 
Sbjct: 73  N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFG----NILS 127

Query: 174 YPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQ 233
                D+  ++G+AFV +E+  AA  A  K+      L    + V      KE + E   
Sbjct: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKM--NGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 234 RVKV---LYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRD-------YAFVHFFNRED 283
           + K    +Y++N      +E++K  F++F  G    VK +RD       + FV +   ED
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHED 243

Query: 284 AVAAMSVMNGKCIDGASIEVTLAK 307
           A  A+  MNGK I G  I V  A+
Sbjct: 244 ANKAVEEMNGKEISGKIIFVGRAQ 267


>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
           sapiens]
          Length = 484

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 27/195 (13%)

Query: 62  EVFVGKIPRDMYEDELVPVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRI 120
           ++F+G+IPR++ E +L P+FE  GKIYE  ++ + F+G ++G AF+ Y  +E A  A   
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 121 LNNYEIRPGKFIGVCVSL--------DNC--------RLFIGAIPKEKKKEEILDEMKKV 164
           L+  +  PG    + V           +C        +LF+G + K++ +    D+++++
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQSE----DDVRRL 170

Query: 165 TE--GVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWG--HTIQVDW 220
            E  G ++        D   ++G AFV+Y SH A A A    + G+  + G   ++ V +
Sbjct: 171 FEAFGNIEECTILRGPD-GNSKGCAFVKYSSH-AEAQAAINALHGSQTMPGASSSLVVKF 228

Query: 221 ADPEKEVDEETMQRV 235
           AD +KE     MQ++
Sbjct: 229 ADTDKERTMRRMQQM 243



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 26/73 (35%), Positives = 41/73 (56%)

Query: 57  PPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQL 116
           PP   ++FVG + +   ED++  +FE  G I E  ++    G ++G AFV Y++  EAQ 
Sbjct: 147 PPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQA 206

Query: 117 AIRILNNYEIRPG 129
           AI  L+  +  PG
Sbjct: 207 AINALHGSQTMPG 219


>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
           sapiens]
          Length = 485

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 55/196 (28%), Positives = 100/196 (51%), Gaps = 28/196 (14%)

Query: 62  EVFVGKIPRDMYEDELVPVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRI 120
           ++F+G+IPR++ E +L P+FE  GKIYE  ++ + F+G ++G AF+ Y  +E A  A   
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 121 LNNYEIRPGKFIGVCVS-----------------LDNCRLFIGAIPKEKKKEEILDEMKK 163
           L+  +  PG    + V                    + +LF+G + K++ +    D++++
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSE----DDVRR 170

Query: 164 VTE--GVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWG--HTIQVD 219
           + E  G ++        D   ++G AFV+Y SH A A A    + G+  + G   ++ V 
Sbjct: 171 LFEAFGNIEECTILRGPD-GNSKGCAFVKYSSH-AEAQAAINALHGSQTMPGASSSLVVK 228

Query: 220 WADPEKEVDEETMQRV 235
           +AD +KE     MQ++
Sbjct: 229 FADTDKERTMRRMQQM 244



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 26/74 (35%), Positives = 42/74 (56%)

Query: 56  PPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQ 115
           PP +  ++FVG + +   ED++  +FE  G I E  ++    G ++G AFV Y++  EAQ
Sbjct: 147 PPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQ 206

Query: 116 LAIRILNNYEIRPG 129
            AI  L+  +  PG
Sbjct: 207 AAINALHGSQTMPG 220


>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 55/196 (28%), Positives = 100/196 (51%), Gaps = 28/196 (14%)

Query: 62  EVFVGKIPRDMYEDELVPVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRI 120
           ++F+G+IPR++ E +L P+FE  GKIYE  ++ + F+G ++G AF+ Y  +E A  A   
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 121 LNNYEIRPGKFIGVCVS-----------------LDNCRLFIGAIPKEKKKEEILDEMKK 163
           L+  +  PG    + V                    + +LF+G + K++ +    D++++
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSE----DDVRR 170

Query: 164 VTE--GVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWG--HTIQVD 219
           + E  G ++        D   ++G AFV+Y SH A A A    + G+  + G   ++ V 
Sbjct: 171 LFEAFGNIEECTILRGPD-GNSKGCAFVKYSSH-AEAQAAINALHGSQTMPGASSSLVVK 228

Query: 220 WADPEKEVDEETMQRV 235
           +AD +KE     MQ++
Sbjct: 229 FADTDKERTMRRMQQM 244



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 26/74 (35%), Positives = 42/74 (56%)

Query: 56  PPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQ 115
           PP +  ++FVG + +   ED++  +FE  G I E  ++    G ++G AFV Y++  EAQ
Sbjct: 147 PPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQ 206

Query: 116 LAIRILNNYEIRPG 129
            AI  L+  +  PG
Sbjct: 207 AAINALHGSQTMPG 220


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 74/291 (25%), Positives = 128/291 (43%), Gaps = 41/291 (14%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILN 122
           +F+  + + +    L   F   G I   +++ + +G ++GY FV + T+E A+ AI  +N
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMN 159

Query: 123 NYEIRPGK-FIGVCVSLDNCRLFIGAIPKEKKK-------EEILDEMKKVTEGVVD--VI 172
              +   K F+G   S       +GA  KE          E++ DE  K   G     + 
Sbjct: 160 GMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALS 219

Query: 173 VYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETM 232
           V     +  K++GF FV +E H  A  A  ++     +L G  I V  A  +K+V+ +T 
Sbjct: 220 VKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGRA--QKKVERQTE 275

Query: 233 QRVKV---------------LYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRD----- 272
            + K                LYV+NL     +E ++ EF+ F  G +   K + +     
Sbjct: 276 LKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPF--GTITSAKVMMEGGRSK 333

Query: 273 -YAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQ 322
            + FV F + E+A  A++ MNG+ +    + V LA+   ++   + HL  Q
Sbjct: 334 GFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ---RKEERQAHLTNQ 381



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 66/262 (25%), Positives = 113/262 (43%), Gaps = 24/262 (9%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEF-SGENRGYAFVMYTTKEEAQLAIRIL 121
           ++VG +  D+ E  L   F  AG I   R+  +  +  + GYA+V +    +A+ A+  +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 122 NNYEIRPGKFIGVCVSLDNCRL--------FIGAIPKEKKKEEILDEMKKVTEGVVDVIV 173
           N +++  GK + +  S  +  L        FI  + K    + + D          +++ 
Sbjct: 73  N-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFG----NILS 127

Query: 174 YPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQ 233
                D+  ++G+ FV +E+  AA  A  K+      L    + V      KE + E   
Sbjct: 128 CKVVCDENGSKGYGFVHFETQEAAERAIEKM--NGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 234 RVKV---LYVRNLMISTTEETIKAEFNKFKPGAVERVK-----KLRDYAFVHFFNREDAV 285
           R K    +Y++N      +E +K  F KF P    +V      K + + FV F   EDA 
Sbjct: 186 RAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQ 245

Query: 286 AAMSVMNGKCIDGASIEVTLAK 307
            A+  MNGK ++G  I V  A+
Sbjct: 246 KAVDEMNGKELNGKQIYVGRAQ 267


>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
           sapiens]
          Length = 614

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 69/274 (25%), Positives = 123/274 (44%), Gaps = 35/274 (12%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENR-GYAFVMYTTKEEAQLAIRIL 121
           ++VG +  D+ E  L   F  AG I   R+  + +     GYA++ +    +A+ A+  +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72

Query: 122 NNYEIRPGKFIGVCVSLDNCRLFIGAIPKE--KKKEEILDE--MKKVTEGVVDVIVYPSA 177
           N +E+  G+ I +  S  +  L    +     K  E+ +D   +        +++    A
Sbjct: 73  N-FEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131

Query: 178 TDKTKNRGFAFVEYESHRAAAMA----------RRKLIPGTFQLWGHTIQVDWADPEKEV 227
            D+  +RGF FV +E+H AA  A           RK+  G F+           + E E+
Sbjct: 132 CDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFK--------SRREREAEL 183

Query: 228 DEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRD-------YAFVHFFN 280
               ++   + YV+NL +   E+ ++  F++F  G +  VK +RD       + FV+F  
Sbjct: 184 GARALEFTNI-YVKNLPVDVDEQGLQDLFSQF--GKMLSVKVMRDNSGHSRCFGFVNFEK 240

Query: 281 REDAVAAMSVMNGKCIDGASIEVTLA-KPVNKEN 313
            E+A  A+  MNGK + G  +    A K V ++N
Sbjct: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQN 274



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 65/272 (23%), Positives = 112/272 (41%), Gaps = 30/272 (11%)

Query: 63  VFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILN 122
           +F+  +   +    L   F   G I   ++  +  G +RG+ FV + T E AQ AI  +N
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTMN 159

Query: 123 NYEIRPGK-FIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTE-GVVDVI-------- 172
              +   K F+G   S       +GA   E     + +    V E G+ D+         
Sbjct: 160 GMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLS 219

Query: 173 VYPSATDKTKNRGFAFVEYESHRAAAMA----RRKLIPGTFQLWGHTIQVDWADPEKEVD 228
           V     +   +R F FV +E H  A  A      K + G     G   +      E +  
Sbjct: 220 VKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRR 279

Query: 229 EETMQRVKV-------LYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRD------YAF 275
            E M++ ++       LYV+NL  S  ++ ++ EF+ +  G +   K + +      + F
Sbjct: 280 FEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPY--GVITSAKVMTEGGHSKGFGF 337

Query: 276 VHFFNREDAVAAMSVMNGKCIDGASIEVTLAK 307
           V F + E+A  A++ MNG+ +    + V LA+
Sbjct: 338 VCFSSPEEATKAVTEMNGRIVGTKPLYVALAQ 369


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,876,391
Number of Sequences: 37866
Number of extensions: 1136181
Number of successful extensions: 5584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 127
Number of HSP's that attempted gapping in prelim test: 4822
Number of HSP's gapped (non-prelim): 601
length of query: 533
length of database: 18,247,518
effective HSP length: 107
effective length of query: 426
effective length of database: 14,195,856
effective search space: 6047434656
effective search space used: 6047434656
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.