Guide to the Human Genome
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Search of human proteins with 21450659

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21450659 RIB43A domain with coiled-coils 1 isoform 2 [Homo
sapiens]
         (192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21450659 RIB43A domain with coiled-coils 1 isoform 2 [Homo sa...   388   e-108
gi|72534784 RIB43A domain with coiled-coils 1 isoform 1 [Homo sa...   363   e-101
gi|241666448 RIB43A domain with coiled-coils 2 [Homo sapiens]          94   7e-20
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    37   0.013
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    37   0.013
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                35   0.039
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]    35   0.051
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]     35   0.051
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre...    35   0.051
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]            34   0.067
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    34   0.087
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    33   0.11 
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    33   0.11 
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    33   0.11 
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    33   0.11 
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    33   0.11 
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                 33   0.11 
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    33   0.15 
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]        33   0.19 
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]        33   0.19 
gi|148746195 trichohyalin [Homo sapiens]                               33   0.19 
gi|7661936 scaffold attachment factor B2 [Homo sapiens]                33   0.19 
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            32   0.33 
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            32   0.33 
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    32   0.33 
gi|109452611 chromosome 14 open reading frame 140 isoform a [Hom...    32   0.33 
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           32   0.33 
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   32   0.43 
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             32   0.43 
gi|225579095 S-phase cyclin A-associated protein in the ER isofo...    31   0.57 

>gi|21450659 RIB43A domain with coiled-coils 1 isoform 2 [Homo
           sapiens]
          Length = 192

 Score =  388 bits (996), Expect = e-108
 Identities = 192/192 (100%), Positives = 192/192 (100%)

Query: 1   MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60
           MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER
Sbjct: 1   MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60

Query: 61  SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120
           SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW
Sbjct: 61  SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120

Query: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180
           KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY
Sbjct: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180

Query: 181 TGKQPGPPDSET 192
           TGKQPGPPDSET
Sbjct: 181 TGKQPGPPDSET 192


>gi|72534784 RIB43A domain with coiled-coils 1 isoform 1 [Homo
           sapiens]
          Length = 379

 Score =  363 bits (933), Expect = e-101
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60
           MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER
Sbjct: 1   MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60

Query: 61  SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120
           SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW
Sbjct: 61  SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120

Query: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180
           KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY
Sbjct: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180

Query: 181 T 181
           T
Sbjct: 181 T 181


>gi|241666448 RIB43A domain with coiled-coils 2 [Homo sapiens]
          Length = 377

 Score = 94.0 bits (232), Expect = 7e-20
 Identities = 54/170 (31%), Positives = 94/170 (55%)

Query: 9   DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
           D ++ A +  RR+ E  RQ R FN RNR++G D +A + QV D+K +EA E+++   +  
Sbjct: 8   DLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAA 67

Query: 69  SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLS 128
              Q D ++ +LE  +    + L + + +F++  Q+ +  REF L DP  + K LP   S
Sbjct: 68  EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127

Query: 129 YSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDE 178
            ++     + +Q F GEDL+   R + Q+ Q R    +QQ+E + A+ ++
Sbjct: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQ 177



 Score = 32.0 bits (71), Expect = 0.33
 Identities = 36/171 (21%), Positives = 77/171 (45%), Gaps = 26/171 (15%)

Query: 20  RNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQM 79
           R + +E QNR ++++             Q  + K   A ++  EA Y  +++Q+D   + 
Sbjct: 151 RKKFQEEQNREWSLQ-------------QQREWKNARAEQKCAEALYTETRLQFDETAKH 197

Query: 80  LEKEEADRTRQLAKKVQEFRE---------QKQQLKNGREFSLWDPGQVWKG--LPTYLS 128
           L+K E+   + +   V++F +         +KQ+ K  +E +L +   + +G  L     
Sbjct: 198 LQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQ 257

Query: 129 YSNTYPGPASL--QYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVD 177
            + +  GP  +    + G   ++  ++R+ Q Q      R Q+E++Q  +D
Sbjct: 258 QAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLD 308


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 36.6 bits (83), Expect = 0.013
 Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 17/175 (9%)

Query: 5   KQSTDTKEAAAIEARRNREKE-RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
           K+    K+   +EARR +E+E R+ R+            +  + ++  +K+ E  ER ++
Sbjct: 624 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE------ERRHQELLQKKKEEEQERLRK 677

Query: 64  AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
           AA            ++ E+ E +R R+  ++ QE REQ+++ +  RE       Q  +  
Sbjct: 678 AAEAK---------RLAEQREQER-REQERREQERREQERREQERREQERQLAEQERRRE 727

Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDE 178
              L                 E L R+   + ++ + +   ERQ QE+Q+ K  E
Sbjct: 728 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 36.6 bits (83), Expect = 0.013
 Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 17/175 (9%)

Query: 5   KQSTDTKEAAAIEARRNREKE-RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
           K+    K+   +EARR +E+E R+ R+            +  + ++  +K+ E  ER ++
Sbjct: 620 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE------ERRHQELLQKKKEEEQERLRK 673

Query: 64  AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
           AA            ++ E+ E +R R+  ++ QE REQ+++ +  RE       Q  +  
Sbjct: 674 AAEAK---------RLAEQREQER-REQERREQERREQERREQERREQERQLAEQERRRE 723

Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDE 178
              L                 E L R+   + ++ + +   ERQ QE+Q+ K  E
Sbjct: 724 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 35.0 bits (79), Expect = 0.039
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 7/101 (6%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDV- 75
           E  R RE+ER+      R +    D +       +R++ E   R KEAAY      +++ 
Sbjct: 408 EREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467

Query: 76  ---VVQMLEKE---EADRTRQLAKKVQEFREQKQQLKNGRE 110
                +  EKE   E +R R++AK+ +  +E  +   + R+
Sbjct: 468 ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD 508



 Score = 30.4 bits (67), Expect = 0.97
 Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 1/101 (0%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
           +E    E  R RE+ER+      R R    D      +  DR R    +R +E +   ++
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379

Query: 71  VQYDVVVQMLEKE-EADRTRQLAKKVQEFREQKQQLKNGRE 110
            +     +  ++E E +R R+  ++ +  RE++++ +  RE
Sbjct: 380 DRSRSREKSRDRERERERERERERERERERERERERERERE 420



 Score = 30.4 bits (67), Expect = 0.97
 Identities = 38/197 (19%), Positives = 89/197 (45%), Gaps = 21/197 (10%)

Query: 3   NIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSK 62
           N  +S   +++   E  R RE+ER+      R R    + +    +  ++ ++   E  +
Sbjct: 378 NKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDE 437

Query: 63  EAAYGTSQVQYDVVVQMLEKEEADRTR------QLAKKVQEFREQKQQLKNGREFSLWDP 116
           E AY   +++     ++ EKE A + R      +  KK +E+ ++ ++ +  R     + 
Sbjct: 438 EDAYERRKLER----KLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRR----EM 489

Query: 117 GQVWKGLPTYL-SYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYN-LERQQQEQQQA 174
            +  K L  +L  Y +    P   +Y+ G  L +  RLR ++ +   +  +R++++++  
Sbjct: 490 AKEAKRLKEFLEDYDDDRDDP---KYYRGSALQK--RLRDREKEMEADERDRKREKEELE 544

Query: 175 KVDENYTGKQPGPPDSE 191
           ++ +    +    PD+E
Sbjct: 545 EIRQRLLAEGHPDPDAE 561


>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
          Length = 1068

 Score = 34.7 bits (78), Expect = 0.051
 Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 22/188 (11%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQ-ALNNQVGDRKRREAAERSKEAAYGTS 69
           ++A+A EAR N+ KE+ +   +V   ++  +   A    V  + + E A   ++ A+   
Sbjct: 438 RKASATEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVE 497

Query: 70  QVQYDVVVQMLEKEE--ADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYL 127
           QV+ +  +++ EK +      R+L  K  E    ++ L +  +       ++   L T  
Sbjct: 498 QVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQ----SKSELSSRLDTLS 553

Query: 128 SYSNTYPGPA---SLQYFSGEDLDRDT---------RLRMQQGQFRYNL-ERQQQEQ--Q 172
           +  +   G          + + L R+T         R   +QG+ +  L ER+ QEQ  +
Sbjct: 554 AEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLR 613

Query: 173 QAKVDENY 180
           Q  +DE +
Sbjct: 614 QRLLDEQF 621


>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
          Length = 1048

 Score = 34.7 bits (78), Expect = 0.051
 Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 22/188 (11%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQ-ALNNQVGDRKRREAAERSKEAAYGTS 69
           ++A+A EAR N+ KE+ +   +V   ++  +   A    V  + + E A   ++ A+   
Sbjct: 418 RKASATEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVE 477

Query: 70  QVQYDVVVQMLEKEE--ADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYL 127
           QV+ +  +++ EK +      R+L  K  E    ++ L +  +       ++   L T  
Sbjct: 478 QVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQ----SKSELSSRLDTLS 533

Query: 128 SYSNTYPGPA---SLQYFSGEDLDRDT---------RLRMQQGQFRYNL-ERQQQEQ--Q 172
           +  +   G          + + L R+T         R   +QG+ +  L ER+ QEQ  +
Sbjct: 534 AEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLR 593

Query: 173 QAKVDENY 180
           Q  +DE +
Sbjct: 594 QRLLDEQF 601


>gi|41152097 DNA segment on chromosome X and Y (unique) 155
           expressed sequence isoform 1 [Homo sapiens]
          Length = 695

 Score = 34.7 bits (78), Expect = 0.051
 Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 13/104 (12%)

Query: 3   NIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSK 62
           NIK S D+ +  +  + + R+ ERQ              +Q L  Q  ++KRRE     +
Sbjct: 252 NIKVSFDSTKHLSDASIKKRQLERQK-------------LQELEQQREEQKRREKEAEER 298

Query: 63  EAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLK 106
           + A    Q + + + +  ++EE  R R+  ++ +E R  +++L+
Sbjct: 299 QRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLE 342


>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 34.3 bits (77), Expect = 0.067
 Identities = 22/107 (20%), Positives = 55/107 (51%), Gaps = 6/107 (5%)

Query: 4   IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
           I++  D +     E +R R+++R+   +  R+R    + Q    +  DRKR +  ER ++
Sbjct: 84  IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQ 143

Query: 64  AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
              G  + +     ++  +++ DR R++  + + +R+++++ +  RE
Sbjct: 144 REIGIDKDR-----EIETEKDRDREREMG-ETERYRDRERERQKQRE 184



 Score = 29.6 bits (65), Expect = 1.6
 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
           E  R RE+ERQ +    R+R    +++    +  DR+R+   ER +       + ++   
Sbjct: 59  ERERQRERERQRKRAKERHREKDREIE----KDRDRQRKRDRERQRWRDRDRKRERWGDR 114

Query: 77  VQMLEKE-EADRTRQLAKKVQEFREQKQQLKNG 108
            +  E E + +R RQ  +K ++ RE+++Q + G
Sbjct: 115 DRETETERQEERERQRDRKREKDRERQRQREIG 147


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 33.9 bits (76), Expect = 0.087
 Identities = 23/94 (24%), Positives = 41/94 (43%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
           E  R R+++RQ      RNR  G + +    +  +R+R    + ++E          D  
Sbjct: 338 EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQ 397

Query: 77  VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
            +   + E DR  Q   + Q  RE+ ++ + GRE
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRE 431



 Score = 31.6 bits (70), Expect = 0.43
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 11/100 (11%)

Query: 5   KQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
           ++ TD +     E  RNR+KER+      R    G D Q    +  +R+R+  AE+ +E 
Sbjct: 106 ERQTDRERDRQREKERNRQKERERE--TEREGERGRDRQTDGQR--ERERQRDAEKERER 161

Query: 65  AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQ 104
                  Q D   Q   +    + R+  K  QE RE+++Q
Sbjct: 162 -------QTDRERQRQTERNRQKEREREKNRQERRERERQ 194



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 22/97 (22%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA---AYGTSQVQY 73
           E +R+REKER+ +    R+R    + +    +  +R+     ER ++         + Q 
Sbjct: 96  ERQRDREKERERQTDRERDRQR--EKERNRQKERERETEREGERGRDRQTDGQRERERQR 153

Query: 74  DVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
           D   +   + + +R RQ  +  Q+ RE+++  +  RE
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190



 Score = 27.3 bits (59), Expect = 8.2
 Identities = 18/106 (16%), Positives = 45/106 (42%)

Query: 5   KQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
           K+ TD +     +  R REK+ +    + R      + +   ++  DR RR+     +  
Sbjct: 225 KRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTD 284

Query: 65  AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
                + + D   +   + + +R R+  +  +  RE++++ +  R+
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 6/103 (5%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
           +E    E R  RE+E + R   +R +   +       Q  +RKRRE    A R +E A  
Sbjct: 733 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 789

Query: 68  TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
             + Q   + +  E+EE  +  +  ++++E R ++++ +   E
Sbjct: 790 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 42/165 (25%), Positives = 68/165 (41%), Gaps = 26/165 (15%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
           +E AA  AR   E+E Q R    R R M  +   L ++  +RKR+E              
Sbjct: 838 EEEAAKWARE--EEEAQRRLEENRLR-MEEEAARLRHEEEERKRKE-------------- 880

Query: 71  VQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYS 130
                 +++  ++E  R RQ  ++     +Q+QQ +   +  L       +   T    S
Sbjct: 881 ------LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 934

Query: 131 NTYPGPASLQYFSGEDLDRDTR--LRMQQGQFRYNLERQQQEQQQ 173
                 A +Q    E+ +R  R   R QQ +    L++QQQ+QQQ
Sbjct: 935 QATLSLAEIQKLE-EERERQLREEQRRQQRELMKALQQQQQQQQQ 978



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 33/169 (19%), Positives = 67/169 (39%), Gaps = 21/169 (12%)

Query: 4    IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
            ++   + ++   +E +R +E  RQ +    +  +  +  Q    Q+   K   ++   ++
Sbjct: 869  LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 926

Query: 64   AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
            +     Q Q  + +  ++K E +R RQL    +E R Q+++L    +       Q   G 
Sbjct: 927  SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 983

Query: 124  PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQ 172
                  S T                  + L +QQ + R   ++QQQ+QQ
Sbjct: 984  GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQ 1016


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 6/103 (5%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
           +E    E R  RE+E + R   +R +   +       Q  +RKRRE    A R +E A  
Sbjct: 760 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 816

Query: 68  TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
             + Q   + +  E+EE  +  +  ++++E R ++++ +   E
Sbjct: 817 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 42/165 (25%), Positives = 68/165 (41%), Gaps = 26/165 (15%)

Query: 11   KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
            +E AA  AR   E+E Q R    R R M  +   L ++  +RKR+E              
Sbjct: 865  EEEAAKWARE--EEEAQRRLEENRLR-MEEEAARLRHEEEERKRKE-------------- 907

Query: 71   VQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYS 130
                  +++  ++E  R RQ  ++     +Q+QQ +   +  L       +   T    S
Sbjct: 908  ------LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 961

Query: 131  NTYPGPASLQYFSGEDLDRDTR--LRMQQGQFRYNLERQQQEQQQ 173
                  A +Q    E+ +R  R   R QQ +    L++QQQ+QQQ
Sbjct: 962  QATLSLAEIQKLE-EERERQLREEQRRQQRELMKALQQQQQQQQQ 1005



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 33/169 (19%), Positives = 67/169 (39%), Gaps = 21/169 (12%)

Query: 4    IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
            ++   + ++   +E +R +E  RQ +    +  +  +  Q    Q+   K   ++   ++
Sbjct: 896  LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 953

Query: 64   AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
            +     Q Q  + +  ++K E +R RQL    +E R Q+++L    +       Q   G 
Sbjct: 954  SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 1010

Query: 124  PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQ 172
                  S T                  + L +QQ + R   ++QQQ+QQ
Sbjct: 1011 GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQ 1043


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 6/103 (5%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
           +E    E R  RE+E + R   +R +   +       Q  +RKRRE    A R +E A  
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 795

Query: 68  TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
             + Q   + +  E+EE  +  +  ++++E R ++++ +   E
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 42/165 (25%), Positives = 68/165 (41%), Gaps = 26/165 (15%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
           +E AA  AR   E+E Q R    R R M  +   L ++  +RKR+E              
Sbjct: 844 EEEAAKWARE--EEEAQRRLEENRLR-MEEEAARLRHEEEERKRKE-------------- 886

Query: 71  VQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYS 130
                 +++  ++E  R RQ  ++     +Q+QQ +   +  L       +   T    S
Sbjct: 887 ------LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940

Query: 131 NTYPGPASLQYFSGEDLDRDTR--LRMQQGQFRYNLERQQQEQQQ 173
                 A +Q    E+ +R  R   R QQ +    L++QQQ+QQQ
Sbjct: 941 QATLSLAEIQKLE-EERERQLREEQRRQQRELMKALQQQQQQQQQ 984



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 33/169 (19%), Positives = 67/169 (39%), Gaps = 21/169 (12%)

Query: 4    IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
            ++   + ++   +E +R +E  RQ +    +  +  +  Q    Q+   K   ++   ++
Sbjct: 875  LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 932

Query: 64   AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
            +     Q Q  + +  ++K E +R RQL    +E R Q+++L    +       Q   G 
Sbjct: 933  SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 989

Query: 124  PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQ 172
                  S T                  + L +QQ + R   ++QQQ+QQ
Sbjct: 990  GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQ 1022


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 6/103 (5%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
           +E    E R  RE+E + R   +R +   +       Q  +RKRRE    A R +E A  
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 795

Query: 68  TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
             + Q   + +  E+EE  +  +  ++++E R ++++ +   E
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 42/165 (25%), Positives = 68/165 (41%), Gaps = 26/165 (15%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
           +E AA  AR   E+E Q R    R R M  +   L ++  +RKR+E              
Sbjct: 844 EEEAAKWARE--EEEAQRRLEENRLR-MEEEAARLRHEEEERKRKE-------------- 886

Query: 71  VQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYS 130
                 +++  ++E  R RQ  ++     +Q+QQ +   +  L       +   T    S
Sbjct: 887 ------LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940

Query: 131 NTYPGPASLQYFSGEDLDRDTR--LRMQQGQFRYNLERQQQEQQQ 173
                 A +Q    E+ +R  R   R QQ +    L++QQQ+QQQ
Sbjct: 941 QATLSLAEIQKLE-EERERQLREEQRRQQRELMKALQQQQQQQQQ 984



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 33/169 (19%), Positives = 67/169 (39%), Gaps = 21/169 (12%)

Query: 4    IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
            ++   + ++   +E +R +E  RQ +    +  +  +  Q    Q+   K   ++   ++
Sbjct: 875  LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 932

Query: 64   AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
            +     Q Q  + +  ++K E +R RQL    +E R Q+++L    +       Q   G 
Sbjct: 933  SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 989

Query: 124  PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQ 172
                  S T                  + L +QQ + R   ++QQQ+QQ
Sbjct: 990  GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQ 1022


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 35/173 (20%), Positives = 74/173 (42%), Gaps = 5/173 (2%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAE--RSKEAAYGTSQVQYD 74
           E  R +E++   +   V+ +   V  Q    +  + + RE  E  R +E      + Q +
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286

Query: 75  VVVQMLEKEEADRTR--QLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNT 132
              Q  E+EE  R +  Q+ ++ ++ REQ++Q++   E       Q+W+           
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ 346

Query: 133 YPGPASLQYFSGEDLDR-DTRLRMQQGQFRYNLERQQQEQQQAKVDENYTGKQ 184
                       E + + + ++R Q+ Q R   E+ +++++Q +  E   G+Q
Sbjct: 347 MWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399



 Score = 31.6 bits (70), Expect = 0.43
 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 2/104 (1%)

Query: 1   MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60
           M   K+ T+ +E    +  + RE+E Q R    + R     ++    Q+G  K+ E    
Sbjct: 278 MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG--KQEEQMWE 335

Query: 61  SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQ 104
            KE  +   +  +    QM E+EE  + ++   + QE + +KQ+
Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 36/183 (19%), Positives = 77/183 (42%), Gaps = 20/183 (10%)

Query: 4   IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
           +K+  +T +    +  + RE+E Q R    + R     V+    QV   + +E   R +E
Sbjct: 37  LKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQV---REQEGQVREQE 93

Query: 64  AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
                 + Q    V+  E +  ++  Q+ ++  + REQ+ Q++          GQV +  
Sbjct: 94  GQVREQEGQ----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ- 148

Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTGK 183
                          ++   G+  +++ ++R Q+GQ R    + ++++ Q +  E   G+
Sbjct: 149 ------------EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGE 196

Query: 184 QPG 186
           Q G
Sbjct: 197 QEG 199


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 9/108 (8%)

Query: 17  EARRNR-EKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQV-QYD 74
           EARR R E++R    F  + ++M  +V+    ++  ++R+E+ ++  E      Q+   D
Sbjct: 638 EARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRD 697

Query: 75  VVVQMLEKEE-------ADRTRQLAKKVQEFREQKQQLKNGREFSLWD 115
            V +  E  E        D  R++  K +E   +KQ+L   RE +LW+
Sbjct: 698 FVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWE 745


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 29/150 (19%), Positives = 64/150 (42%), Gaps = 30/150 (20%)

Query: 12  EAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQV 71
           E   ++ RR+  + ++ R+            + L  ++ D +  +A    +++   TSQ 
Sbjct: 741 EDPGVQKRRSSRQVKRKRY-----------TEDLEFKISDEEADDADAAGRDSPSNTSQS 789

Query: 72  QYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSN 131
           +        ++E  D    + +K+   R  K+Q ++G E  + +          Y+ Y N
Sbjct: 790 E--------QQESVDAEGPVVEKIMSSRSVKKQKESGEEVEIEE---------FYVKYKN 832

Query: 132 TYPGPASLQYFSGEDLDRDTRLRMQQGQFR 161
                   Q+ S EDL++D R++ +  +F+
Sbjct: 833 F--SYLHCQWASIEDLEKDKRIQQKIKRFK 860


>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
          Length = 285

 Score = 32.7 bits (73), Expect = 0.19
 Identities = 24/108 (22%), Positives = 49/108 (45%), Gaps = 14/108 (12%)

Query: 1   MYNIKQSTDTKEAAAIEARR---NREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREA 57
           + ++K   + + A   E +R    REKERQNR    R R           +  +  RR+A
Sbjct: 120 LVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERAR-----------REEEENRRKA 168

Query: 58  AERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQL 105
            + +++    ++ + +   +Q  E++   R  +  KK +   E+++ L
Sbjct: 169 EDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVL 216


>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
          Length = 295

 Score = 32.7 bits (73), Expect = 0.19
 Identities = 24/108 (22%), Positives = 49/108 (45%), Gaps = 14/108 (12%)

Query: 1   MYNIKQSTDTKEAAAIEARR---NREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREA 57
           + ++K   + + A   E +R    REKERQNR    R R           +  +  RR+A
Sbjct: 130 LVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERAR-----------REEEENRRKA 178

Query: 58  AERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQL 105
            + +++    ++ + +   +Q  E++   R  +  KK +   E+++ L
Sbjct: 179 EDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVL 226


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 32.7 bits (73), Expect = 0.19
 Identities = 35/167 (20%), Positives = 68/167 (40%), Gaps = 23/167 (13%)

Query: 18  ARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVV 77
           A    + E+Q R      +    ++     +  +R+ R A E   ++  G    ++    
Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP--- 205

Query: 78  QMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLW--DPGQVWKGLPTYLSYSNTYPG 135
                EE  R R+L +  ++ RE+KQQ +  R+  ++  +  + W+   T L        
Sbjct: 206 ----DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE---- 257

Query: 136 PASLQYFSGEDLDRDTRLRMQQGQFR------YNLERQQQEQQQAKV 176
               +    E+  R   L+ ++ Q R         ERQ++EQQQ ++
Sbjct: 258 ----EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300



 Score = 32.7 bits (73), Expect = 0.19
 Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 9/164 (5%)

Query: 9    DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
            + +E    E R  R ++ Q R +    ++   + Q L  +   R+R+E     +E  Y  
Sbjct: 908  EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE-----RERQYRK 962

Query: 69   SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLS 128
             +       Q+L +E   R RQ  +K  ++RE+ ++L+   E  L +  +  +       
Sbjct: 963  DKKLQQKEEQLLGEEPEKRRRQEREK--KYREE-EELQQEEEQLLREEREKRRRQEWERQ 1019

Query: 129  YSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQ 172
            Y          +    E+ ++  RL+ ++ Q+R   E QQ+E+Q
Sbjct: 1020 YRKKDELQQEEEQLLREEREK-RRLQERERQYREEEELQQEEEQ 1062



 Score = 32.3 bits (72), Expect = 0.25
 Identities = 40/167 (23%), Positives = 71/167 (42%), Gaps = 30/167 (17%)

Query: 22   REKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLE 81
            +E+E Q      R+R    + Q L  Q  DRK RE   RS+E      + ++    Q L 
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE-----PERKFLEEEQQLH 1525

Query: 82   KEEADRTRQLAKKVQEFREQK--QQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASL 139
            +++  R R+  ++ Q+ R Q+  QQ +  R+    +  Q+ +                  
Sbjct: 1526 RQQ--RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ--------------EREE 1569

Query: 140  QYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTGKQPG 186
            Q  S ++ DR  RL  Q+        R+Q+++++   DE    +Q G
Sbjct: 1570 QQLSRQERDRKFRLEEQK-------VRRQEQERKFMEDEQQLRRQEG 1609



 Score = 31.2 bits (69), Expect = 0.57
 Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
           E ++ + +ERQ+R F           + +  +  ++ + E  +R +E      Q++    
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR---- 279

Query: 77  VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
              LE++E  R RQ  ++ Q+   ++QQL+  +E
Sbjct: 280 --KLERQELRRERQEEEQQQQRLRREQQLRRKQE 311



 Score = 31.2 bits (69), Expect = 0.57
 Identities = 36/165 (21%), Positives = 74/165 (44%), Gaps = 17/165 (10%)

Query: 17   EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
            E RR +E ERQ R    +   +  + + L  +  +++RR+  ER         Q +    
Sbjct: 1069 ETRRRQELERQYR----KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEE--- 1121

Query: 77   VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
             Q+L +E   R RQ  ++  ++RE+++  +   +    +P +  +           Y   
Sbjct: 1122 -QLLREEREKRRRQELER--QYREEEEVQQEEEQLLREEPEKRRRQ-----ELERQYREE 1173

Query: 137  ASLQYFSGEDL--DRDTRLRMQQGQFRYNLERQQQEQQQAKVDEN 179
              LQ    + L  +++ R + ++ Q+R   E Q+Q+++Q   DE+
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218



 Score = 30.8 bits (68), Expect = 0.74
 Identities = 34/165 (20%), Positives = 71/165 (43%), Gaps = 29/165 (17%)

Query: 19   RRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQ 78
            ++ R++E++ R +  R+R    + Q    +  + KRR+   + ++               
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK--------------- 1318

Query: 79   MLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPAS 138
             L +EE +  R+  +  ++FRE++Q L+   E  L    +  K     L +         
Sbjct: 1319 QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH--------- 1369

Query: 139  LQYFSGEDLDRDTRLRMQQGQFRYNLERQ----QQEQQQAKVDEN 179
             Q    + L+ + RLR Q+ + ++  E Q    Q+ +QQ + D +
Sbjct: 1370 -QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413



 Score = 30.4 bits (67), Expect = 0.97
 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 7/157 (4%)

Query: 17   EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
            E ++ R +ER+ +    R+R    + Q L+ Q  DRK RE  ++ +        ++ +  
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE-- 1452

Query: 77   VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
             Q L +E   + R+  + +QE RE++Q  +  R+    +  Q  +       +       
Sbjct: 1453 -QQLRQERHRKFREEEQLLQE-REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ---E 1507

Query: 137  ASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQ 173
               Q    + L+ + +L  QQ Q ++  E QQ  +Q+
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 37/160 (23%), Positives = 70/160 (43%), Gaps = 13/160 (8%)

Query: 17   EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER--SKEAAYGTSQVQYD 74
            E +R R +ER+ +F     ++   + +    Q  DRK RE  ++   +E      + +  
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438

Query: 75   VVVQMLEKEEADRTRQL-AKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTY 133
            V  Q  E++  +  +QL  ++ ++FRE++Q L+   E  L    +  K L          
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE-------- 1490

Query: 134  PGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQ 173
                 L+    +   R+  LR Q+ + ++  E QQ  +QQ
Sbjct: 1491 --EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528



 Score = 29.6 bits (65), Expect = 1.6
 Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 24/161 (14%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
           + RR +E+ER+ +    R +    + Q    +   + RRE  ER ++      + +    
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERRE--QQLRREQEERREQQLRREQEEERREQ 362

Query: 77  VQMLEKEEADRTRQLAKKVQEFREQ----KQQLKNGREFSLWDPGQVWKGLPTYLSYSNT 132
               E+EE  R +QL ++ Q  REQ    +QQL+  RE  L    Q+ +           
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRR----------- 409

Query: 133 YPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQ 173
                  Q    + L R+ +LR +Q + R+  + +Q+ ++Q
Sbjct: 410 -----EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445



 Score = 29.6 bits (65), Expect = 1.6
 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 28/143 (19%)

Query: 51  DRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
           +++RR+  ER KE             +Q LE+EE  + R+ A+++QE  +  Q+ +  R 
Sbjct: 818 EQRRRQRREREKE-------------LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864

Query: 111 FSLWDPGQVWKGL---PTYLSYSNTYPGPA---------SLQYFSGEDLDRDTR--LRMQ 156
                  Q W+              Y  PA          L     E+L R+ R   R Q
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924

Query: 157 QGQFRYNLERQ-QQEQQQAKVDE 178
           + + +Y  E Q QQE++Q   +E
Sbjct: 925 EQERQYREEEQLQQEEEQLLREE 947



 Score = 28.9 bits (63), Expect = 2.8
 Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 11/94 (11%)

Query: 17   EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
            E ++ R +ER  +F          + Q L +Q  DRK RE             Q++ +  
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-----------EEQLRQERE 1808

Query: 77   VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
             Q L  ++ D   +  ++  +  EQ+Q+L+  R+
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 12/100 (12%)

Query: 17  EARRNREKERQNRFFNV----RNRVMGVDVQALNNQVGDR-----KRREAAERSKEAAYG 67
           + +R++E+ER+ R+  +    R        Q L  +  +R     KR+E  ER ++    
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534

Query: 68  TSQV---QYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQ 104
             Q+   Q +   Q+L++EE  R  Q  ++ +  REQ+++
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER 574


>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
          Length = 953

 Score = 32.7 bits (73), Expect = 0.19
 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 8/102 (7%)

Query: 5   KQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAA--ERSK 62
           K+  D      I+ +R RE++RQ      R R +    +    +  +R++R  A  ER +
Sbjct: 606 KEKRDILSFDKIKEQRERERQRQ------REREIRETERRREREQREREQRLEAFHERKE 659

Query: 63  EAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQ 104
           +A     ++Q +   Q LE+E  +R R   ++++  RE++++
Sbjct: 660 KARLQRERLQLECQRQRLERERMERERLERERMRVERERRKE 701


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 32.0 bits (71), Expect = 0.33
 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 5   KQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
           K+    +E+   + RR REK ++ R    R R  G        + G+RK+ E   + +  
Sbjct: 49  KEGKKERESERKKERREREKRKRERE-KERKRERGK-----KEKKGERKKEERERKKRRR 102

Query: 65  AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
                + +     +  EK+E  RT +  K+ +   E+K++ +  RE
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148



 Score = 30.8 bits (68), Expect = 0.74
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 18/109 (16%)

Query: 5   KQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE--AAERSK 62
           ++  + KE    +  R +E+ER+ R    R +V   + +    +  +RK+RE    ER K
Sbjct: 139 RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198

Query: 63  EAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFRE-QKQQLKNGRE 110
           E                  KE  +R ++  KK +  +E QK +  N RE
Sbjct: 199 ERE---------------RKERRERKKERKKKEERKKERQKDRQTNWRE 232



 Score = 28.9 bits (63), Expect = 2.8
 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 13/93 (13%)

Query: 5   KQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
           ++  + K+    E  R +EKER+ R    RNR           +  +R+R+E  ER KE 
Sbjct: 163 RKKRERKQVGEKEEER-KEKERKERKKRERNR---------KERKKERERKERRERKKER 212

Query: 65  AYGTSQV---QYDVVVQMLEKEEADRTRQLAKK 94
                +    Q D      EKE   R R+  KK
Sbjct: 213 KKKEERKKERQKDRQTNWREKERGKRERKERKK 245


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 32.0 bits (71), Expect = 0.33
 Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 16/107 (14%)

Query: 5   KQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
           K+ TD +     +  R+RE++R+      RNR  G +      +  DR+R    +R +E 
Sbjct: 89  KRQTDRER----DKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERER 144

Query: 65  AYGTSQVQYDVVVQMLEKEEADRTRQ-LAKKVQEFREQKQQLKNGRE 110
                        Q   K E DR RQ  A++ +  +E+K++ K  R+
Sbjct: 145 QR-----------QRERKRETDRERQRWAEREERKKERKKERKKERK 180



 Score = 28.9 bits (63), Expect = 2.8
 Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 13/94 (13%)

Query: 17  EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
           E  R R+KER  +    R      + Q    +  +RKR+   ER K+             
Sbjct: 53  EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDR------------ 100

Query: 77  VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
                K E DR R+  +K    R+++ + +  RE
Sbjct: 101 -DRERKRETDRNRERNRKGGRERDKQTERERDRE 133



 Score = 27.7 bits (60), Expect = 6.3
 Identities = 24/116 (20%), Positives = 51/116 (43%), Gaps = 10/116 (8%)

Query: 5   KQSTDTKEAAAIEARRNREKERQN---RFFNVRNRVMGVDVQALNNQVGDRKRREAAERS 61
           ++  +T      E  R+R++ER+N   R    R R    +     ++  +R+R++  +R 
Sbjct: 6   ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65

Query: 62  KEAAYGTSQVQYDVVVQMLEKE-------EADRTRQLAKKVQEFREQKQQLKNGRE 110
           ++    T +       +  ++E       E D+ R   +K +  R +++  K GRE
Sbjct: 66  RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 32.0 bits (71), Expect = 0.33
 Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 8/92 (8%)

Query: 19  RRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQ 78
           RR+R++ER+    N R R    D         +++R  + ERSKE      Q     V +
Sbjct: 349 RRDRDREREKE--NERGRRRDRDYDKERGNEREKERERSRERSKE------QRSRGEVEE 400

Query: 79  MLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
              KE+ D  R    K    +E+K      RE
Sbjct: 401 KKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRE 432



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 20/96 (20%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 9   DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
           D+K+       R+RE++ ++R    R+R  G   ++ + +   + + E+ E+S + +   
Sbjct: 418 DSKKEKKHSRSRSRERKHRSRS---RSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG 474

Query: 69  SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQ 104
           SQ + D  V+  +K E   +++ ++K    +E+  +
Sbjct: 475 SQGRTD-SVEKSKKREHSPSKEKSRKRSRSKERSHK 509


>gi|109452611 chromosome 14 open reading frame 140 isoform a [Homo
           sapiens]
          Length = 456

 Score = 32.0 bits (71), Expect = 0.33
 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 14/195 (7%)

Query: 5   KQSTDTKEAAA-----IEARRNREKERQNRFFNVRNR----VMGVDVQALNNQ--VGDRK 53
           ++S  T EA       +  R    +E  +R F VRN+    V+G  + A   +  V +  
Sbjct: 147 RKSCSTGEAGTDGDHNVYPRPPEPREFSSRNFGVRNQGNFSVVGTVLAATQAEKAVANFD 206

Query: 54  RREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSL 113
           R E  +  +  A G S  +     Q+L + +  +T +  +++Q  +EQ ++ +NG    +
Sbjct: 207 RTEWVQIRRLEAAGESLEEEIRRKQILLRGKLKKTEEELRRIQTQKEQAKENENGELQKI 266

Query: 114 WDPGQVWKGLPTYLSYSNTY-PGPASLQYFSGEDLDRDTRLRMQQ--GQFRYNLERQQQE 170
             P    KG  +   Y   + P     + FS +  + +T  R QQ  G F+++  R Q+ 
Sbjct: 267 ILPRSRVKGNKSNTMYKPIFSPEFEFEEEFSRDRREDETWGRSQQNSGPFQFSDYRIQRL 326

Query: 171 QQQAKVDENYTGKQP 185
           +++  V  N   + P
Sbjct: 327 KRERLVASNNKIRDP 341


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 32.0 bits (71), Expect = 0.33
 Identities = 21/98 (21%), Positives = 50/98 (51%), Gaps = 9/98 (9%)

Query: 6   QSTDTKEAAAIEARRNREKERQNRFFNVRNRV--MGVDVQALNNQVGDRKRREAAERSKE 63
           Q T  +  +  ++ +   K+ + +  ++   +  + V+ ++L   + +RK++ A ERS+ 
Sbjct: 698 QETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQ- 756

Query: 64  AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQ 101
                ++ + D + +  + EE D+ RQL KK +   +Q
Sbjct: 757 -----AEEEIDEIRKSYQ-EELDKLRQLLKKTRVSTDQ 788


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 31.6 bits (70), Expect = 0.43
 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 4/108 (3%)

Query: 12   EAAAIEARRNREKER-QNRFFNVRNRVMGVDVQA---LNNQVGDRKRREAAERSKEAAYG 67
            EA  I+  + +E  + QN   N +  V+    +A   L  ++  R++ E A+        
Sbjct: 903  EAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQE 962

Query: 68   TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWD 115
              Q Q   +   L+K    +  +LA   +E    KQQL   RE ++W+
Sbjct: 963  FVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWE 1010



 Score = 27.3 bits (59), Expect = 8.2
 Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 3/72 (4%)

Query: 43  QALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKK-VQEFREQ 101
           Q LN+++  +++RE   R  E    + + QYD  ++ LEK++     +L ++     R++
Sbjct: 846 QQLNSKL--QQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDE 903

Query: 102 KQQLKNGREFSL 113
            +++K  +E  L
Sbjct: 904 AKRIKGEQEKEL 915


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 31.6 bits (70), Expect = 0.43
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 10/114 (8%)

Query: 7   STDTKEAAAIEARRNR----EKERQNRFFNVRNRVMGVDVQALNNQVGDRK--RREAAER 60
           +TD +EA  + A + R    ++E++ R    +  +     + L  +V + +  RRE   R
Sbjct: 473 TTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESR 532

Query: 61  SKEAAYGTS---QVQYDVVVQML-EKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
             EA        Q+Q     + L E+EEA+R ++  ++    RE+ ++++  RE
Sbjct: 533 RLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQERE 586



 Score = 28.9 bits (63), Expect = 2.8
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 25/93 (26%)

Query: 11  KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
           +E+  +EA + REKE Q            +  QA    + +R+  E A+R KE       
Sbjct: 529 EESRRLEAEQAREKEEQ------------LQRQAEERALREREEAERAQRQKEE------ 570

Query: 71  VQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQ 103
                  +   +EEA+R RQ  +K  +  EQ++
Sbjct: 571 -------EARVREEAERVRQEREKHFQREEQER 596


>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
           b [Homo sapiens]
          Length = 1154

 Score = 31.2 bits (69), Expect = 0.57
 Identities = 38/199 (19%), Positives = 81/199 (40%), Gaps = 48/199 (24%)

Query: 4   IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRV-MGVDVQALNNQVGDRKRREAAERSK 62
           I +S    E   ++A++ REK R+ +   ++  +    DV+    ++ D++RR   E+  
Sbjct: 294 IAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLL 353

Query: 63  EAAYGTSQVQYDVVVQMLEKEEAD------------------------RTRQLAKKVQEF 98
            A +   +VQ   +V+  ++EEA                            Q   ++QE 
Sbjct: 354 HAEF-KREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEE 412

Query: 99  REQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQG 158
           R+++Q+ K  R+ ++ +  +                          E   R   L M++ 
Sbjct: 413 RQRRQEEKQARDEAVQERKRA----------------------LEAERQARVEELLMKRK 450

Query: 159 QFRYNLERQQQEQQQAKVD 177
           +    +E+Q+QE+++A+ D
Sbjct: 451 EQEARIEQQRQEKEKARED 469


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,500,718
Number of Sequences: 37866
Number of extensions: 325339
Number of successful extensions: 2302
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 1760
Number of HSP's gapped (non-prelim): 497
length of query: 192
length of database: 18,247,518
effective HSP length: 97
effective length of query: 95
effective length of database: 14,574,516
effective search space: 1384579020
effective search space used: 1384579020
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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