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Search of human proteins with 21450645
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens]
(873 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens] 1724 0.0
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 64 8e-10
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 59 2e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 59 2e-08
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 58 4e-08
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 55 2e-07
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 55 2e-07
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 55 2e-07
gi|57864582 hornerin [Homo sapiens] 53 1e-06
gi|188497758 ubiquitin associated protein 2-like isoform a [Homo... 53 1e-06
gi|188497756 ubiquitin associated protein 2-like isoform b [Homo... 53 1e-06
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 53 1e-06
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 53 1e-06
gi|50962882 G patch domain containing 8 [Homo sapiens] 52 2e-06
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 52 2e-06
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 52 2e-06
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 52 3e-06
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 52 3e-06
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 51 4e-06
gi|4503729 FK506 binding protein 52 [Homo sapiens] 51 4e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 51 4e-06
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 7e-06
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 49 2e-05
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 49 2e-05
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 49 2e-05
gi|217330641 IWS1 homolog [Homo sapiens] 49 2e-05
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 49 2e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens] 49 2e-05
gi|50083281 KIAA1853 protein [Homo sapiens] 49 2e-05
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 47 6e-05
>gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens]
Length = 873
Score = 1724 bits (4464), Expect = 0.0
Identities = 873/873 (100%), Positives = 873/873 (100%)
Query: 1 MTDSDEDALKVDQGPSRDIPKPWVIPAPKGILQHIFGTSHVFQSICDVKPKVTGLTVPLK 60
MTDSDEDALKVDQGPSRDIPKPWVIPAPKGILQHIFGTSHVFQSICDVKPKVTGLTVPLK
Sbjct: 1 MTDSDEDALKVDQGPSRDIPKPWVIPAPKGILQHIFGTSHVFQSICDVKPKVTGLTVPLK 60
Query: 61 VREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRR 120
VREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRR
Sbjct: 61 VREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRR 120
Query: 121 AYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACL 180
AYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACL
Sbjct: 121 AYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACL 180
Query: 181 LALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA 240
LALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA
Sbjct: 181 LALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA 240
Query: 241 RMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQE 300
RMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQE
Sbjct: 241 RMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQE 300
Query: 301 FDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRD 360
FDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRD
Sbjct: 301 FDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRD 360
Query: 361 EQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRK 420
EQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRK
Sbjct: 361 EQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRK 420
Query: 421 QFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVLLLNPKQPKLSLLM 480
QFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVLLLNPKQPKLSLLM
Sbjct: 421 QFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVLLLNPKQPKLSLLM 480
Query: 481 TNLFPGMSVEEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQH 540
TNLFPGMSVEEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQH
Sbjct: 481 TNLFPGMSVEEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQH 540
Query: 541 SWKQGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVA 600
SWKQGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVA
Sbjct: 541 SWKQGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVA 600
Query: 601 SLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGN 660
SLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGN
Sbjct: 601 SLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGN 660
Query: 661 NREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNS 720
NREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNS
Sbjct: 661 NREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNS 720
Query: 721 SKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARG 780
SKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARG
Sbjct: 721 SKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARG 780
Query: 781 RSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQG 840
RSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQG
Sbjct: 781 RSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQG 840
Query: 841 MSSTSSKAESTWGPSPSLSKTEVDQDLTYYEAV 873
MSSTSSKAESTWGPSPSLSKTEVDQDLTYYEAV
Sbjct: 841 MSSTSSKAESTWGPSPSLSKTEVDQDLTYYEAV 873
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 63.5 bits (153), Expect = 8e-10
Identities = 67/275 (24%), Positives = 123/275 (44%), Gaps = 24/275 (8%)
Query: 601 SLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGN 660
S S S S S S +G+S++ S RS S + S +++S
Sbjct: 188 SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR------SKSRSRSQSRSR 241
Query: 661 NREALSHGPRKIKA-----TQGQRQSLSKTEPTQSQRRNSS----KTKATIHKRNSSKTK 711
+++ S P K K+ + G+ +S SK + + + N + K+++ ++ SK++
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301
Query: 712 ATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEP---SKTKTTRSP 768
+ +RR + R + +G+S K+ RQS S + G R SK+K R
Sbjct: 302 SRSQERRVEEEKRGSVSRGRSQEKS-----LRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
Query: 769 RQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRS 828
R+R R+ +R RS S+ +G R S+K + D++ S S++ +R
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKERE 416
Query: 829 -SKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTE 862
+K+E +Q + +G S + + T S S SK++
Sbjct: 417 HAKSESSQREGRGESENAGTNQETRSRSRSNSKSK 451
Score = 48.1 bits (113), Expect = 3e-05
Identities = 41/193 (21%), Positives = 91/193 (47%), Gaps = 21/193 (10%)
Query: 677 GQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNS-------SKTRATQGQ 729
G++ L + +P +RR+ S++++ H R+ S+++ ++ R S SK+R+
Sbjct: 167 GRKIRLVEDKPGSRRRRSYSRSRS--HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRS 224
Query: 730 GQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVD 789
G S ++ Q +S S+ E ++ P +E S++++ + + R + A + V
Sbjct: 225 GSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVG 284
Query: 790 ATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAE 849
+ RS +S +K S++ + + + + ++G+SQ S S++
Sbjct: 285 KPKSRSPSRHKSKSK-----------SRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 850 S-TWGPSPSLSKT 861
S + G S S S++
Sbjct: 334 SRSKGGSRSRSRS 346
Score = 47.0 bits (110), Expect = 8e-05
Identities = 51/252 (20%), Positives = 112/252 (44%), Gaps = 13/252 (5%)
Query: 563 QVKPGSSEGEAEAPEEEEEKEKE----KKEEKKSELIPSKVASLSDSYLDQTSSASSMSF 618
Q + S + ++ +P +E+ + + K K + K+ + + ++ S S
Sbjct: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 619 RTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQS---SDSGNNREALSHGPRKIKAT 675
++ S ++ + +E R S + + SL +++S S G+ + S K K
Sbjct: 297 KSKSRSRSQERRVEEEKRG-SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR- 354
Query: 676 QGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSK 735
+G+++S E ++S+ R+ SK++ + + + +KA S+++ T +Q + S S
Sbjct: 355 KGRKRS---REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411
Query: 736 TEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRS 795
++ + + SS+ E +G + + TRS + K K R A++ RS
Sbjct: 412 SKEREHAKSESSQREG-RGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRS 470
Query: 796 RGLLRSSTKTEA 807
R RS + + +
Sbjct: 471 RSKSRSRSASRS 482
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/225 (20%), Positives = 99/225 (44%), Gaps = 7/225 (3%)
Query: 504 QLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGEPLIATSEELKATPEIPQ 563
Q E+ ++ + G P+ RH+ + + Q + E + S + Q
Sbjct: 272 QAEEKIQNNDNVGKPKS--RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329
Query: 564 VKPGS-SEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTG 622
+ S S+G + + K K+K++ +K S+ S S S +++ S G
Sbjct: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAG 389
Query: 623 TSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSL 682
+S+ + +S S + + K++SS E+ + G + T+ + +S
Sbjct: 390 SSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTN--QETRSRSRSN 447
Query: 683 SKTEPT-QSQRRNSSKTKATIHKRNSSKTK-ATQSQRRNSSKTRA 725
SK++P S+ R+ SK+ + R+ S+++ A++S R+ S++ +
Sbjct: 448 SKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 58.9 bits (141), Expect = 2e-08
Identities = 73/298 (24%), Positives = 118/298 (39%), Gaps = 20/298 (6%)
Query: 554 ELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTS-- 611
E++ E + PG A + EKE E+KEEK+SE P VA Q
Sbjct: 432 EIEPDKECKSLSPGKENVSAL----DMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQ 487
Query: 612 SASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRK 671
S S ++ S+ E ++ + T + L + D L+ P +
Sbjct: 488 SQSQPVLQSQPPSQPEDLSLAVLQPTPQVT----QEQGHLLPERKDFPVESVKLTEVPVE 543
Query: 672 IKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQ 731
T +S SKT+ T+S+ R ++ K +SK+++ S +SS + + G
Sbjct: 544 PVLTV-HPESKSKTK-TRSRSRGRARNK-------TSKSRSRSSSSSSSSSSSTSSSSGS 594
Query: 732 SSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDAT 791
SSS ++ SSS + R S T ++ R R R R R R S VD
Sbjct: 595 SSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRS-VDRK 653
Query: 792 QGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAE 849
+ + GL RS ++ + SK + ++ +RS GK S K++
Sbjct: 654 RRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSD 711
Score = 40.4 bits (93), Expect = 0.007
Identities = 62/357 (17%), Positives = 132/357 (36%), Gaps = 29/357 (8%)
Query: 529 ELERQKALALQHSWKQGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKE 588
++ + +A + S K+ E + +EE KA E +V E E + + + +E E
Sbjct: 277 QINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGE 336
Query: 589 EKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAV----- 643
E++ E+ + V S ++ ++ M + +E S Q+ + V
Sbjct: 337 EEEKEI--AIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVE 394
Query: 644 ----TFSDSSLLKT---QSSDSGNNREALSHGP---------RKIKATQGQRQSLSKTEP 687
+D +++T +S + N + P ++ K+ ++++S +
Sbjct: 395 NVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDM 454
Query: 688 TQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSS 747
+ K + + +Q Q + S+++ S + + Q +
Sbjct: 455 EKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTP 514
Query: 748 EIEATQG---PRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTK 804
++ QG P ++ ++ + V S +K T+ RSRG R+ T
Sbjct: 515 QVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTK---TRSRSRGRARNKTS 571
Query: 805 TEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKT 861
S+ S S + SS + + +S SS+S+ S+ S S S +
Sbjct: 572 KSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSS 628
Score = 38.9 bits (89), Expect = 0.021
Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 7/172 (4%)
Query: 609 QTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHG 668
++ S + R+ G + + S RS+S+++ + S +S SS SG++ S
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSK--SRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS 608
Query: 669 PRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQG 728
+ R S S T + R S+++ H R+ ++ +RR++S +
Sbjct: 609 SSSSTSGSSSRDSSSSTSSSSESR---SRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHK 665
Query: 729 QGQSSSKTEATQGQRQSSSEIEATQGPRQEP-SKTKTTRSPRQRPRKVKAAR 779
+ S + T+G + +S + + + S +++RS R R K R
Sbjct: 666 SSKGGSSRD-TKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKR 716
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 58.9 bits (141), Expect = 2e-08
Identities = 72/307 (23%), Positives = 131/307 (42%), Gaps = 20/307 (6%)
Query: 547 PLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSY 606
P A+ ++ P+ P+ P SS E+ P + K K A S+
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES---PKPAPAPGSH 450
Query: 607 LDQTSSASSMSFRTTGTSETEMSAICQEYR--STSATAVTFSDSSLLKTQSSDSGNNREA 664
+ +SS +S + R+ G ++ + S R S + T + G++R
Sbjct: 451 REISSSPTSKN-RSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR-- 507
Query: 665 LSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTR 724
S P+ ++ QR S++ P + R S + RN+ + ++S RR S +R
Sbjct: 508 -SRSPQWRRSRSAQRWGRSRS-PQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565
Query: 725 ATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWR 784
+ +G+S S+T A +G+ +S T R+ S+T T R R R A RGRS R
Sbjct: 566 SPATRGRSRSRTPARRGRSRS-----RTPARRRSRSRTPTRRRSRSR---TPARRGRS-R 616
Query: 785 PSKVDATQGRSRGLLRSSTKTEA-FYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSS 843
+ R+R +R +++ + S S S+T +G+ + + A + +S+ +
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR 676
Query: 844 TSSKAES 850
S ++ S
Sbjct: 677 RSGRSRS 683
Score = 54.3 bits (129), Expect = 5e-07
Identities = 73/322 (22%), Positives = 128/322 (39%), Gaps = 28/322 (8%)
Query: 552 SEELKATPEIPQVKP--GSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQ 609
S ++PE P+ P GS + +P + K +K PS+ S S
Sbjct: 431 SRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRS--PA 488
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGP 669
T+ RT S Q RS SA S S + +S + S
Sbjct: 489 TAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT 548
Query: 670 RKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKA-------TQSQRRNSSK 722
++ ++ R+ S + ++ R+ S+T A R+ S+T A T ++RR+ S+
Sbjct: 549 QRRGRSRSARRGRSHSRSPATRGRSRSRTPAR-RGRSRSRTPARRRSRSRTPTRRRSRSR 607
Query: 723 TRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRK-----VKA 777
T A +G+ +S + R ++ P + ++++ R+P +R R +
Sbjct: 608 TPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS-RTPARRGRSRSRTPARR 666
Query: 778 ARGRSWRP--------SKVDATQGRSRGLL--RSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
R RS P S+ A +GRSR R +++ + S S+T +G+
Sbjct: 667 GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726
Query: 828 SSKAEGAQGKSQGMSSTSSKAE 849
SS+ + SQ S ++S E
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPE 748
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/190 (22%), Positives = 88/190 (46%), Gaps = 12/190 (6%)
Query: 596 PSKVASLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQS 655
PS +A+L + ++SS+SS S ++ +S + S+ S+S ++ + S+ S L Q
Sbjct: 2518 PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS-----SSSSGSSSSDSEGSSLPVQP 2572
Query: 656 SDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQS 715
AL P A + + EPT ++R+ S + ++ +SS + ++ S
Sbjct: 2573 E------VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
Query: 716 QRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV 775
+SS + ++ SSS + + + + P++ P + +RSPR+ +
Sbjct: 2627 SSSSSSSSSSSSSSSSSSSSSSPSPA-KPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685
Query: 776 KAARGRSWRP 785
+ +R S+ P
Sbjct: 2686 RDSRSLSYSP 2695
Score = 50.1 bits (118), Expect = 9e-06
Identities = 46/204 (22%), Positives = 87/204 (42%), Gaps = 6/204 (2%)
Query: 568 SSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETE 627
SS + + E + E + +PS + ++ + + + R +S +
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611
Query: 628 MSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEP 687
S+ S+S+++ + S SS + SS S ++ + S P K Q + S +P
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSPSPAK-PGPQALPKPASPKKP 2668
Query: 688 TQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQR---Q 744
+RR+ S K R+S + +RR S + + Q SSS+ + +GQR +
Sbjct: 2669 PPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR 2728
Query: 745 SSSEIEATQGPRQEPSKTKTTRSP 768
S S + P P + +++RSP
Sbjct: 2729 SPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 48.9 bits (115), Expect = 2e-05
Identities = 56/256 (21%), Positives = 96/256 (37%), Gaps = 15/256 (5%)
Query: 552 SEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIP-----------SKVA 600
S +++PE P + G +PE + K + + S P S+ A
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKT-KSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
Query: 601 SLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGN 660
S S +T S + E S + RS S+ + G
Sbjct: 1711 SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770
Query: 661 NREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNS 720
R K + T+ + +S S ++ ++R+ S+++ T +R S + R+ S
Sbjct: 1771 QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES 1830
Query: 721 SKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARG 780
S+T + + +G+ S+T T +R S A + + T R R R + R
Sbjct: 1831 SRTSSRRRRGR--SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 781 RSWRPSKVDATQGRSR 796
RS R S V + RSR
Sbjct: 1889 RS-RTSPVSRRRSRSR 1903
Score = 47.4 bits (111), Expect = 6e-05
Identities = 78/351 (22%), Positives = 128/351 (36%), Gaps = 51/351 (14%)
Query: 551 TSEELKATPEIPQVK---PGSSE--GEAEAPEEEEEKEKEKKEEKKSELIP--SKVASLS 603
+S E KA P+ P+ + P S E + P+ E + ++K P + S S
Sbjct: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
Query: 604 DSYLDQTSSASSMSFRTTGTSETEMSAICQ---EYRSTSATAVTFSDSSLLKTQSSDSGN 660
LD SAS R+ S + A + RS S ++ S L + S SG+
Sbjct: 1542 SQELDVKPSASPQE-RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGS 1600
Query: 661 NREALSHGPRKIKATQGQRQS------LSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQ 714
+ E +A G S + P +S+ +SSK + + +SS + +
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPE 1660
Query: 715 SQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPR------------------ 756
++ + R ++ + +K+ +R S S E T+ R
Sbjct: 1661 HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRT 1720
Query: 757 ----------QEPSKTKTTRSPRQR-----PR-KVKAARGRSWRPSKVDATQGRSRGLLR 800
P + +RS R+R PR K + RGRS P + RSR
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 801 SSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAEST 851
+ T S S S + Q RS +G S S + ++ ES+
Sbjct: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/179 (24%), Positives = 83/179 (46%), Gaps = 12/179 (6%)
Query: 679 RQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKA------TQSQRRNSSKTRATQGQGQS 732
R+ S++ + R+ S+T A R+ S+T A +++ RR S++R+ +G+S
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713
Query: 733 SSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQ 792
S+T +G+ SSS E R ++++ SP + ++ + R RS + ++
Sbjct: 714 HSRTPQRRGRSGSSS--ERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPR---SK 768
Query: 793 GRSRGLLRSSTKTEAFYDSNWSLSKTEYAQ-GQGQRSSKAEGAQGKSQGMSSTSSKAES 850
+SR LR S + S + ++ G Q +K+ +S+ SS K +S
Sbjct: 769 AKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS 827
Score = 45.4 bits (106), Expect = 2e-04
Identities = 64/305 (20%), Positives = 115/305 (37%), Gaps = 40/305 (13%)
Query: 572 EAEAPEEEEEKEKEKKEEKKSELIPSKVAS----LSDSYLDQTSSASSMSFRTTGTSETE 627
E E EE E++ EE++ I KVA+ L + ++ + R T +
Sbjct: 67 ELRCLELEEMMEEQGYEEQQ---IQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQ 123
Query: 628 MSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEP 687
++ + ++ A SDS + + REA P K R+S S P
Sbjct: 124 LAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSP 183
Query: 688 TQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSS 747
T Q++ K + S++ + + +R+ SSK + + + +S + + +
Sbjct: 184 TPKQKKKKKKK----DRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKR- 238
Query: 748 EIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSW-RPSKVDATQGRSRGLLRSSTKTE 806
+ + K K +RS P+ +A R S S D ++ RSR
Sbjct: 239 --------KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRS--------- 281
Query: 807 AFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTEVDQD 866
+ +KT G+ S A G +G+ + S+ +T PS +T Q
Sbjct: 282 -------AAAKTHTTALAGRSPSPASGRRGEG---DAPFSEPGTTSTQRPSSPETATKQP 331
Query: 867 LTYYE 871
+ YE
Sbjct: 332 SSPYE 336
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/340 (21%), Positives = 131/340 (38%), Gaps = 41/340 (12%)
Query: 563 QVKPGSSEGEAEAPEEEEEK-------EKEKKEEKKSELIPSKVAS------------LS 603
++K S+ +PE EE + + + ++ +PS +S LS
Sbjct: 1259 ELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELS 1318
Query: 604 DSYLDQTSSASSMSFRTTGTSETEM-----SAICQEYRSTSATAVTFSDSSLLKTQSSDS 658
+S L + S S + FR +G TEM S + ++ + S +K QS+ S
Sbjct: 1319 NSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRS 1378
Query: 659 GNNREALSHGPRKIKATQGQRQSLSK----TEPTQSQRRNSSKTKATIHKRNSSKTKATQ 714
+ + KA QS+S P R SS + K +T + +
Sbjct: 1379 SGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438
Query: 715 SQRRNSSKTRATQGQGQSSSKTEATQGQR-------QSSSEIEATQGPRQEPS----KTK 763
S+ +S R G S + ++ G + + SE +++ P+ P +++
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498
Query: 764 TTRSPRQRPRKVKAARGRSWRPSKVD-ATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQ 822
+ SP + + R RS S VD T R+ RS + + D S S E ++
Sbjct: 1499 SPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSE 1558
Query: 823 GQGQRSSKAEGAQG-KSQGMSSTSSKAESTWGPSPSLSKT 861
SKA+ + + S +S + +S SP S++
Sbjct: 1559 SDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS 1598
Score = 44.7 bits (104), Expect = 4e-04
Identities = 71/325 (21%), Positives = 126/325 (38%), Gaps = 40/325 (12%)
Query: 556 KATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASS 615
+++PE+ + K S A E + + ++S + S + + SASS
Sbjct: 1692 RSSPELTR-KARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS 1750
Query: 616 MSFRTT---GTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKI 672
+TT G S + Q RS S T + ++ SS S + R S ++
Sbjct: 1751 PRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRV 1810
Query: 673 ---------------------KATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTK 711
+ + +R+ S+T PT S++R+ S+T KR S+++
Sbjct: 1811 TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT-SRKRSRSRTSPAPWKR--SRSR 1867
Query: 712 ATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQR 771
A+ + R S + +S S+T +R+S S T+ + + + R R R
Sbjct: 1868 ASPATHRRSRSRTPLISRRRSRSRTSPV-SRRRSRSRTSVTRRRSRSRASPVSRRRSRSR 1926
Query: 772 PRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKA 831
V R RS P+ T+ RSR T+ S S+T + RS +
Sbjct: 1927 TPPVTRRRSRSRTPT----TRRRSRSRTPPVTRRR-------SRSRTPPVTRRRSRSRTS 1975
Query: 832 EGAQGKSQGMSSTSSKAESTWGPSP 856
+ +S+ +S ++ S SP
Sbjct: 1976 PITRRRSRSRTSPVTRRRSRSRTSP 2000
Score = 43.9 bits (102), Expect = 7e-04
Identities = 76/355 (21%), Positives = 135/355 (38%), Gaps = 28/355 (7%)
Query: 511 GSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGEPLIATSEELKATPEIPQVKPGSSE 570
G + P+G+ R E+ + + + + ++ + + + G S
Sbjct: 1760 GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819
Query: 571 GEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETEMSA 630
+ +P +E + + P S S +TS A R+ + T
Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS---RTSPAPWKRSRSRASPATHR-- 1874
Query: 631 ICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQG---QRQSLSKTEP 687
RS S T + S +T +R S R+ ++ +R+S S+T P
Sbjct: 1875 -----RSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPP 1929
Query: 688 TQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSS 747
++RR+ S+T T +R+ S+T ++RR+ S+T + +S S+T +R S
Sbjct: 1930 V-TRRRSRSRTPTT-RRRSRSRTPPV-TRRRSRSRTPPVT-RRRSRSRTSPITRRRSRSR 1985
Query: 748 EIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEA 807
T+ + + T R R R V R RS P + + RSR L +
Sbjct: 1986 TSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAI-RRRSRSRTPLLPRKR--- 2041
Query: 808 FYDSNWSLSKTEYAQGQGQRSSKAEGAQGK-SQGMSSTSSKAESTWGPSPSLSKT 861
S S++ A + RS A+GK S S + + S G S S++
Sbjct: 2042 ------SRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRS 2090
Score = 43.5 bits (101), Expect = 9e-04
Identities = 49/229 (21%), Positives = 88/229 (38%), Gaps = 9/229 (3%)
Query: 636 RSTSATAVTF--SDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRR 693
RS S T+VT S S S + ++ + + +R+S S+T P ++RR
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPV-TRRR 1957
Query: 694 NSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQ 753
+ S+T +R+ S+T +R S + T+ + +S + + R +S + +
Sbjct: 1958 SRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRR 2017
Query: 754 GPRQEP------SKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEA 807
+ P S+++T PR+R R R S+ T R L RS
Sbjct: 2018 SRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRR 2077
Query: 808 FYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSP 856
S S ++ A R+ + S S + + P+P
Sbjct: 2078 RSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTP 2126
Score = 42.4 bits (98), Expect = 0.002
Identities = 66/307 (21%), Positives = 122/307 (39%), Gaps = 46/307 (14%)
Query: 490 EEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELER---------QKALALQH 540
E+ + ++A + LE+ V + +P + + H+L + A +
Sbjct: 84 EQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISD 143
Query: 541 SWKQG---EPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPS 597
S+ G +P E + PE P KP S E+ + K+K+KK++K
Sbjct: 144 SYVDGSSFDPQRRAREAKQPAPEPP--KPYSLVRESSSSRSPTPKQKKKKKKK------- 194
Query: 598 KVASLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSD 657
D+ + S S R E + S+ +++RS S +S K +S
Sbjct: 195 ----------DRGRRSESSSPRR----ERKKSSKKKKHRSES-------ESKKRKHRSPT 233
Query: 658 SGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQR 717
+ R++ ++ ++T +S T + +SS T + + ++KT T
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
Query: 718 RNSSKTRATQGQGQSS-SKTEATQGQRQSSSEIEATQ--GPRQEPSKTKTTRS-PRQRPR 773
R+ S +G+G + S+ T QR SS E Q P ++ K K +S R P
Sbjct: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
Query: 774 KVKAARG 780
+++ G
Sbjct: 354 PERSSTG 360
Score = 30.4 bits (67), Expect = 7.5
Identities = 57/292 (19%), Positives = 106/292 (36%), Gaps = 29/292 (9%)
Query: 566 PGSSEGEAEAPEEEEEKEKEKKEEKKSEL-IPSKVASLSDSYLDQTSSASSMSFRTTGTS 624
P + P + + +S P++ S + S + + S + S + R +G S
Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPA-RRSGRS 647
Query: 625 ETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSK 684
+ A + RS S T S +T + SG +R + A +G+ S S+
Sbjct: 648 RSRTPA--RRGRSRSRTPAR-RGRSRSRTPARRSGRSRS-------RTPARRGR--SRSR 695
Query: 685 TEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQ 744
T R S + H R + + S +K+R +Q + +S+S E + R
Sbjct: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK-SRI 754
Query: 745 SSSEIEATQGPRQEPSKTKTTR--------SPRQR----PRKVKAARGRSWRPSKVDATQ 792
SS + PR + + R P+Q+ PR+ ++ + S+ +
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814
Query: 793 GRSRGL--LRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMS 842
RS + +KT + + S + G R Q Q ++
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT 866
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 57.8 bits (138), Expect = 4e-08
Identities = 72/342 (21%), Positives = 139/342 (40%), Gaps = 33/342 (9%)
Query: 137 FVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNE 196
+ +Y+Q + ++L +F A L P+ + L L +H+A + +
Sbjct: 68 YAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEA 127
Query: 197 LKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQ 256
K + + ++ Y +L++ + LH+AL LN +H ++L K
Sbjct: 128 AKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLN-RHDLTYIMLGK---------- 176
Query: 257 DAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVT 316
I ++G L A++ +A+E +P + L G +Y +L + A E L
Sbjct: 177 ---IHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDP 233
Query: 317 EDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFF 376
+ + ++ A ++ T+ DF V + V + L+ N G CFF
Sbjct: 234 TNYKAIL--AAGSMMQTHGDFDVALTKYRVVACAV----------PESPPLWNNIGMCFF 281
Query: 377 QLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHN 436
A + ++A L+P D +GL+ M +Q+ A + S AI
Sbjct: 282 GKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTM-------QQYASAFHFLSAAINFQ 334
Query: 437 PQKAQYYLYRAKSRQLLQNIFGARQDVATVLLLNPKQPKLSL 478
P+ + Y+ A + L++I A++ A + L+ P ++L
Sbjct: 335 PKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNL 376
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/321 (23%), Positives = 134/321 (41%), Gaps = 34/321 (10%)
Query: 76 DWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLE-R 134
++E AV F+ AL ++P +D Y R +Y++ + Q + N +++ R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
Query: 135 LTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEK-PCFRYRCMACLLALKQHQACLTLI 193
++F LQ Q F++ A N F+ A + P+ + R + C L + + A + I
Sbjct: 1379 ISFGYNLQAQGKFQK-----AWNHFTIAIDTDPKNYLAYEGRAVVC-LQMGNNFAAMQDI 1432
Query: 194 TNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQ 253
+K TT A+ R ++ F+ +D A+ LNPK+ A + +Q
Sbjct: 1433 NAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
Query: 254 ARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLD 313
Q A ++A++ +P + + + R L++++ A EDF V++
Sbjct: 1492 FSQ-------------ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIE 1538
Query: 314 MVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGD 373
+A +C +Q Y+ LNKAL + + +Y R
Sbjct: 1539 SCPFWAAVYFNRAH----------FYYCLKQ--YELAEEDLNKALSLKPNDALVYNFRAK 1586
Query: 374 CFFQLGNLAFAEADYQQALAL 394
++G + A ADY QAL L
Sbjct: 1587 VRGKIGLIEEAMADYNQALDL 1607
Score = 50.1 bits (118), Expect = 9e-06
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 22/186 (11%)
Query: 288 FLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAY 347
FL RG +Y L ++ A+EDF Q ++ + L + A+ +R +
Sbjct: 1273 FLNRGLIYVELGQYGFALEDF---------KQAALISRTNGSLC---HATAMCHHRINEF 1320
Query: 348 QEGVLLLNKALRDEQQEKGLYINRGDCFFQLGN---LAFAEADYQQALALSPQDEGANTR 404
+E V AL+ Y+ RG+ + + G+ A+ D+ +AL ++P A
Sbjct: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
Query: 405 MGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVA 464
G + G +FQKA NHF+ AI +P+ Y RA + N F A QD+
Sbjct: 1381 FGYNLQAQG-------KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
Query: 465 TVLLLN 470
+ ++
Sbjct: 1434 AAMKIS 1439
Score = 49.7 bits (117), Expect = 1e-05
Identities = 103/500 (20%), Positives = 181/500 (36%), Gaps = 101/500 (20%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQ----------LVDFYALRAEAYLQ 107
P + RG E +W A+ F+ L++D Q ++ +Y L Q
Sbjct: 1049 PKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQ 1108
Query: 108 LCDFSSAAQNLRRA-----YSLQQDNCKHLERLTFVLYLQGQCLFEQCAFL--------- 153
+ + L YS +++ K +E L + + + + CA L
Sbjct: 1109 IAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAE--MTMCALLAKVQMKAKR 1166
Query: 154 ---------DALNVFSHAAELQPEKPCFRYRCM----ACLLA----LKQHQACLTLITNE 196
AL+ SH+ + P+ C+ C + ++ +T +T
Sbjct: 1167 TKEAVEVLKKALDASSHS-DKGPDATTISADCLYNLGLCYMEEGNLQMTYKLAITDLTTA 1225
Query: 197 LKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA------RMLLQKMVAQ 250
+ D + + RA Y +++ + D LLL+ R L+ + Q
Sbjct: 1226 ISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQ 1285
Query: 251 ----AQQARQDAGILAVQGKLQHAL----QRINR----------AIENNPLDPSLFLFRG 292
+ +Q A I G L HA RIN A++ NP ++ RG
Sbjct: 1286 YGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRG 1345
Query: 293 TMYRRLQEFDG---AVEDFLKVLDMVTEDQEDMVR-----QAQRQLLLTYNDF------- 337
Y + A +DFLK L + + + QAQ + +N F
Sbjct: 1346 NSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTD 1405
Query: 338 ----------AVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEAD 387
AV C + G + +N A++ + L NRG +G+ A D
Sbjct: 1406 PKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKD 1464
Query: 388 YQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRA 447
YQ A+ L+P + L G +QF +A ++FS A++ +P+ + RA
Sbjct: 1465 YQDAITLNP-------KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRA 1517
Query: 448 KSRQLLQNIFGARQDVATVL 467
+ +L+ A++D A V+
Sbjct: 1518 ITNTILKKYEEAKEDFANVI 1537
Score = 38.1 bits (87), Expect = 0.036
Identities = 45/204 (22%), Positives = 71/204 (34%), Gaps = 26/204 (12%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQN 117
P ++ S G Q ++ A F+ A+ DP+ Y RA LQ+ + +A Q+
Sbjct: 1372 PAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQD 1431
Query: 118 LRRAYSLQ--------------------------QDNCKHLERLTFVLYLQGQCLFEQCA 151
+ A + QD + + + G F
Sbjct: 1432 INAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
Query: 152 FLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRA 211
F A + FS A + PE LK+++ N ++ A VY RA
Sbjct: 1492 FSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRA 1551
Query: 212 RLYNFLQKPHLCYRDLHSALLLNP 235
Y L++ L DL+ AL L P
Sbjct: 1552 HFYYCLKQYELAEEDLNKALSLKP 1575
Score = 36.6 bits (83), Expect = 0.10
Identities = 60/321 (18%), Positives = 113/321 (35%), Gaps = 46/321 (14%)
Query: 155 ALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLY 214
AL F AA + + C + + + + T LK + D Y+ R Y
Sbjct: 1289 ALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSY 1348
Query: 215 ---NFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHAL 271
+ +D AL +NP + +AR+ L QGK Q A
Sbjct: 1349 MEYGHDEATKQAQKDFLKALHINPAYIKARISFGYN-------------LQAQGKFQKAW 1395
Query: 272 QRINRAIENNPLDPSLF-------LFRGTMYRRLQEFD---------------GAVEDFL 309
AI+ +P + + L G + +Q+ + G + +F+
Sbjct: 1396 NHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFM 1455
Query: 310 KVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYI 369
+D +D + + L +N ++ + + + + +KAL+ + + + + +
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHR-QFSQASDYFSKALKFDPENEYVLM 1514
Query: 370 NRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHF 429
NR L A+ D+ + P + +C KQ++ AE
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFN----RAHFYYC---LKQYELAEEDL 1567
Query: 430 STAIRHNPQKAQYYLYRAKSR 450
+ A+ P A Y +RAK R
Sbjct: 1568 NKALSLKPNDALVYNFRAKVR 1588
Score = 30.8 bits (68), Expect = 5.7
Identities = 38/179 (21%), Positives = 70/179 (39%), Gaps = 24/179 (13%)
Query: 291 RGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQA--QRQLLLTYNDFAVHCYRQGAYQ 348
RG +YR+L + A+ D +V+ + E + A R L+ + D
Sbjct: 923 RGAIYRKLGKLQSAMNDLQRVILL-----EPLFLNAYWHRHLIYLFQD---------KIN 968
Query: 349 EGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLL 408
E + LN + + Y+++ + + ++ A +Y QA+ +P D R G +
Sbjct: 969 EALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM 1028
Query: 409 QEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVL 467
E A + FS I ++P++ L R +N F A +D +L
Sbjct: 1029 YEITNKV--------LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALL 1079
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 22/154 (14%)
Query: 265 GKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVR 324
GKLQ A+ + R I PL + + R +Y + + A++D + + E +
Sbjct: 931 GKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLS 990
Query: 325 QAQRQLLLTYNDFAVHCYRQGAYQEGVLLLN--KALRDEQQEKGLYINRGDCFFQLGNLA 382
+A+ YR G + +LN +A++ + +Y RG+ +++ N
Sbjct: 991 KAE-------------IYR-GKKDITLAILNYTQAIKSTPTDADIYFRRGE-MYEITNKV 1035
Query: 383 FAEADYQQALALSPQDEGANTRMGLLQEKMGFCE 416
A D+ + + P+ A + GL +CE
Sbjct: 1036 LAIDDFSKCIFYDPKRTDALLKRGLF-----YCE 1064
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/321 (23%), Positives = 134/321 (41%), Gaps = 34/321 (10%)
Query: 76 DWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLE-R 134
++E AV F+ AL ++P +D Y R +Y++ + Q + N +++ R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
Query: 135 LTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEK-PCFRYRCMACLLALKQHQACLTLI 193
++F LQ Q F++ A N F+ A + P+ + R + C L + + A + I
Sbjct: 1379 ISFGYNLQAQGKFQK-----AWNHFTIAIDTDPKNYLAYEGRAVVC-LQMGNNFAAMQDI 1432
Query: 194 TNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQ 253
+K TT A+ R ++ F+ +D A+ LNPK+ A + +Q
Sbjct: 1433 NAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
Query: 254 ARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLD 313
Q A ++A++ +P + + + R L++++ A EDF V++
Sbjct: 1492 FSQ-------------ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIE 1538
Query: 314 MVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGD 373
+A +C +Q Y+ LNKAL + + +Y R
Sbjct: 1539 SCPFWAAVYFNRAH----------FYYCLKQ--YELAEEDLNKALSLKPNDALVYNFRAK 1586
Query: 374 CFFQLGNLAFAEADYQQALAL 394
++G + A ADY QAL L
Sbjct: 1587 VRGKIGLIEEAMADYNQALDL 1607
Score = 50.8 bits (120), Expect = 5e-06
Identities = 103/500 (20%), Positives = 181/500 (36%), Gaps = 101/500 (20%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQ----------LVDFYALRAEAYLQ 107
P + RG E +W A+ F+ L++D Q ++ +Y L Q
Sbjct: 1049 PKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQ 1108
Query: 108 LCDFSSAAQNLRRA-----YSLQQDNCKHLERLTFVLYLQGQCLFEQCAFL--------- 153
+ + L YS +++ K +E L + + + + CA L
Sbjct: 1109 IAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAE--MTMCALLAKVQMKAKR 1166
Query: 154 ---------DALNVFSHAAELQPEKPCFRYRCM----ACLLA----LKQHQACLTLITNE 196
AL+ SH+ + P+ C+ C + ++ +T +T
Sbjct: 1167 TKEAVEVLKKALDAISHS-DKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTA 1225
Query: 197 LKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA------RMLLQKMVAQ 250
+ D + + RA Y +++ + D LLL+ R L+ + Q
Sbjct: 1226 ISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQ 1285
Query: 251 ----AQQARQDAGILAVQGKLQHAL----QRINR----------AIENNPLDPSLFLFRG 292
+ +Q A I G L HA RIN A++ NP ++ RG
Sbjct: 1286 YGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRG 1345
Query: 293 TMYRRLQEFDG---AVEDFLKVLDMVTEDQEDMVR-----QAQRQLLLTYNDF------- 337
Y + A +DFLK L + + + QAQ + +N F
Sbjct: 1346 NSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTD 1405
Query: 338 ----------AVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEAD 387
AV C + G + +N A++ + L NRG +G+ A D
Sbjct: 1406 PKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKD 1464
Query: 388 YQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRA 447
YQ A+ L+P + L G +QF +A ++FS A++ +P+ + RA
Sbjct: 1465 YQDAITLNP-------KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRA 1517
Query: 448 KSRQLLQNIFGARQDVATVL 467
+ +L+ A++D A V+
Sbjct: 1518 ITNTILKKYEEAKEDFANVI 1537
Score = 50.1 bits (118), Expect = 9e-06
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 22/186 (11%)
Query: 288 FLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAY 347
FL RG +Y L ++ A+EDF Q ++ + L + A+ +R +
Sbjct: 1273 FLNRGLIYVELGQYGFALEDF---------KQAALISRTNGSLC---HATAMCHHRINEF 1320
Query: 348 QEGVLLLNKALRDEQQEKGLYINRGDCFFQLGN---LAFAEADYQQALALSPQDEGANTR 404
+E V AL+ Y+ RG+ + + G+ A+ D+ +AL ++P A
Sbjct: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
Query: 405 MGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVA 464
G + G +FQKA NHF+ AI +P+ Y RA + N F A QD+
Sbjct: 1381 FGYNLQAQG-------KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
Query: 465 TVLLLN 470
+ ++
Sbjct: 1434 AAMKIS 1439
Score = 38.1 bits (87), Expect = 0.036
Identities = 45/204 (22%), Positives = 71/204 (34%), Gaps = 26/204 (12%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQN 117
P ++ S G Q ++ A F+ A+ DP+ Y RA LQ+ + +A Q+
Sbjct: 1372 PAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQD 1431
Query: 118 LRRAYSLQ--------------------------QDNCKHLERLTFVLYLQGQCLFEQCA 151
+ A + QD + + + G F
Sbjct: 1432 INAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
Query: 152 FLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRA 211
F A + FS A + PE LK+++ N ++ A VY RA
Sbjct: 1492 FSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRA 1551
Query: 212 RLYNFLQKPHLCYRDLHSALLLNP 235
Y L++ L DL+ AL L P
Sbjct: 1552 HFYYCLKQYELAEEDLNKALSLKP 1575
Score = 36.6 bits (83), Expect = 0.10
Identities = 60/321 (18%), Positives = 113/321 (35%), Gaps = 46/321 (14%)
Query: 155 ALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLY 214
AL F AA + + C + + + + T LK + D Y+ R Y
Sbjct: 1289 ALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSY 1348
Query: 215 ---NFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHAL 271
+ +D AL +NP + +AR+ L QGK Q A
Sbjct: 1349 MEYGHDEATKQAQKDFLKALHINPAYIKARISFGYN-------------LQAQGKFQKAW 1395
Query: 272 QRINRAIENNPLDPSLF-------LFRGTMYRRLQEFD---------------GAVEDFL 309
AI+ +P + + L G + +Q+ + G + +F+
Sbjct: 1396 NHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFM 1455
Query: 310 KVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYI 369
+D +D + + L +N ++ + + + + +KAL+ + + + + +
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHR-QFSQASDYFSKALKFDPENEYVLM 1514
Query: 370 NRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHF 429
NR L A+ D+ + P + +C KQ++ AE
Sbjct: 1515 NRAITNTILKKYEEAKEDFANVIESCPFWAAVYFN----RAHFYYC---LKQYELAEEDL 1567
Query: 430 STAIRHNPQKAQYYLYRAKSR 450
+ A+ P A Y +RAK R
Sbjct: 1568 NKALSLKPNDALVYNFRAKVR 1588
Score = 30.8 bits (68), Expect = 5.7
Identities = 38/179 (21%), Positives = 70/179 (39%), Gaps = 24/179 (13%)
Query: 291 RGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQA--QRQLLLTYNDFAVHCYRQGAYQ 348
RG +YR+L + A+ D +V+ + E + A R L+ + D
Sbjct: 923 RGAIYRKLGKLQSAMNDLQRVILL-----EPLFLNAYWHRHLIYLFQD---------KIN 968
Query: 349 EGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLL 408
E + LN + + Y+++ + + ++ A +Y QA+ +P D R G +
Sbjct: 969 EALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM 1028
Query: 409 QEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVL 467
E A + FS I ++P++ L R +N F A +D +L
Sbjct: 1029 YEITNKV--------LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALL 1079
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 22/154 (14%)
Query: 265 GKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVR 324
GKLQ A+ + R I PL + + R +Y + + A++D + + E +
Sbjct: 931 GKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLS 990
Query: 325 QAQRQLLLTYNDFAVHCYRQGAYQEGVLLLN--KALRDEQQEKGLYINRGDCFFQLGNLA 382
+A+ YR G + +LN +A++ + +Y RG+ +++ N
Sbjct: 991 KAE-------------IYR-GKKDITLAILNYTQAIKSTPTDADIYFRRGE-MYEITNKV 1035
Query: 383 FAEADYQQALALSPQDEGANTRMGLLQEKMGFCE 416
A D+ + + P+ A + GL +CE
Sbjct: 1036 LAIDDFSKCIFYDPKRTDALLKRGLF-----YCE 1064
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/321 (23%), Positives = 134/321 (41%), Gaps = 34/321 (10%)
Query: 76 DWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLE-R 134
++E AV F+ AL ++P +D Y R +Y++ + Q + N +++ R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378
Query: 135 LTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEK-PCFRYRCMACLLALKQHQACLTLI 193
++F LQ Q F++ A N F+ A + P+ + R + C L + + A + I
Sbjct: 1379 ISFGYNLQAQGKFQK-----AWNHFTIAIDTDPKNYLAYEGRAVVC-LQMGNNFAAMQDI 1432
Query: 194 TNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQ 253
+K TT A+ R ++ F+ +D A+ LNPK+ A + +Q
Sbjct: 1433 NAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
Query: 254 ARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLD 313
Q A ++A++ +P + + + R L++++ A EDF V++
Sbjct: 1492 FSQ-------------ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIE 1538
Query: 314 MVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGD 373
+A +C +Q Y+ LNKAL + + +Y R
Sbjct: 1539 SCPFWAAVYFNRAH----------FYYCLKQ--YELAEEDLNKALSLKPNDALVYNFRAK 1586
Query: 374 CFFQLGNLAFAEADYQQALAL 394
++G + A ADY QAL L
Sbjct: 1587 VRGKIGLIEEAMADYNQALDL 1607
Score = 51.6 bits (122), Expect = 3e-06
Identities = 103/500 (20%), Positives = 181/500 (36%), Gaps = 101/500 (20%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQ----------LVDFYALRAEAYLQ 107
P + RG E +W A+ F+ L++D Q ++ +Y L Q
Sbjct: 1049 PKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQ 1108
Query: 108 LCDFSSAAQNLRRA-----YSLQQDNCKHLERLTFVLYLQGQCLFEQCAFL--------- 153
+ + L YS +++ K +E L + + + + CA L
Sbjct: 1109 IAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAE--MTMCALLAKVQMKAKR 1166
Query: 154 ---------DALNVFSHAAELQPEKPCFRYRCM----ACLLA----LKQHQACLTLITNE 196
AL+ SH+ + P+ C+ C + ++ +T +T
Sbjct: 1167 TKEAVEVLKKALDAISHS-DKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTA 1225
Query: 197 LKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQA------RMLLQKMVAQ 250
+ D + + RA Y +++ + D LLL+ R L+ + Q
Sbjct: 1226 ISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQ 1285
Query: 251 ----AQQARQDAGILAVQGKLQHAL----QRINR----------AIENNPLDPSLFLFRG 292
+ +Q A I G L HA RIN A++ NP ++ RG
Sbjct: 1286 YGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRG 1345
Query: 293 TMYRRLQEFDG---AVEDFLKVLDMVTEDQEDMVR-----QAQRQLLLTYNDF------- 337
Y + A +DFLK L + + + QAQ + +N F
Sbjct: 1346 NSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTD 1405
Query: 338 ----------AVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEAD 387
AV C + G + +N A++ + L NRG +G+ A D
Sbjct: 1406 PKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKD 1464
Query: 388 YQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRA 447
YQ A+ L+P + L G +QF +A ++FS A++ +P+ + RA
Sbjct: 1465 YQDAITLNP-------KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRA 1517
Query: 448 KSRQLLQNIFGARQDVATVL 467
+ +L+ A++D A V+
Sbjct: 1518 ITNTILKKYEEAKEDFANVI 1537
Score = 50.1 bits (118), Expect = 9e-06
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 22/186 (11%)
Query: 288 FLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAY 347
FL RG +Y L ++ A+EDF Q ++ + L + A+ +R +
Sbjct: 1273 FLNRGLIYVELGQYGFALEDF---------KQAALISRTNGSLC---HATAMCHHRINEF 1320
Query: 348 QEGVLLLNKALRDEQQEKGLYINRGDCFFQLGN---LAFAEADYQQALALSPQDEGANTR 404
+E V AL+ Y+ RG+ + + G+ A+ D+ +AL ++P A
Sbjct: 1321 EEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARIS 1380
Query: 405 MGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVA 464
G + G +FQKA NHF+ AI +P+ Y RA + N F A QD+
Sbjct: 1381 FGYNLQAQG-------KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDIN 1433
Query: 465 TVLLLN 470
+ ++
Sbjct: 1434 AAMKIS 1439
Score = 38.1 bits (87), Expect = 0.036
Identities = 45/204 (22%), Positives = 71/204 (34%), Gaps = 26/204 (12%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQN 117
P ++ S G Q ++ A F+ A+ DP+ Y RA LQ+ + +A Q+
Sbjct: 1372 PAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQD 1431
Query: 118 LRRAYSLQ--------------------------QDNCKHLERLTFVLYLQGQCLFEQCA 151
+ A + QD + + + G F
Sbjct: 1432 INAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQ 1491
Query: 152 FLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRA 211
F A + FS A + PE LK+++ N ++ A VY RA
Sbjct: 1492 FSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRA 1551
Query: 212 RLYNFLQKPHLCYRDLHSALLLNP 235
Y L++ L DL+ AL L P
Sbjct: 1552 HFYYCLKQYELAEEDLNKALSLKP 1575
Score = 37.4 bits (85), Expect = 0.061
Identities = 74/402 (18%), Positives = 144/402 (35%), Gaps = 50/402 (12%)
Query: 74 QADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLE 133
Q ++ A+ + A+ +D + RA Y ++ + A + L D + ++
Sbjct: 1212 QMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDY--GIVLLLDATETVK 1269
Query: 134 RLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLI 193
TF+ +G E + AL F AA + + C + + + +
Sbjct: 1270 LNTFLN--RGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFF 1327
Query: 194 TNELKQDTTNADVYIFRARLY---NFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQ 250
T LK + D Y+ R Y + +D AL +NP + +AR+
Sbjct: 1328 TWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYN--- 1384
Query: 251 AQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLF-------LFRGTMYRRLQEFD- 302
L QGK Q A AI+ +P + + L G + +Q+ +
Sbjct: 1385 ----------LQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINA 1434
Query: 303 --------------GAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQ 348
G + +F+ +D +D + + L +N ++ + + +
Sbjct: 1435 AMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHR-QFS 1493
Query: 349 EGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLL 408
+ +KAL+ + + + + +NR L A+ D+ + P
Sbjct: 1494 QASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFN---- 1549
Query: 409 QEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSR 450
+ +C KQ++ AE + A+ P A Y +RAK R
Sbjct: 1550 RAHFYYC---LKQYELAEEDLNKALSLKPNDALVYNFRAKVR 1588
Score = 30.8 bits (68), Expect = 5.7
Identities = 38/179 (21%), Positives = 70/179 (39%), Gaps = 24/179 (13%)
Query: 291 RGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQA--QRQLLLTYNDFAVHCYRQGAYQ 348
RG +YR+L + A+ D +V+ + E + A R L+ + D
Sbjct: 923 RGAIYRKLGKLQSAMNDLQRVILL-----EPLFLNAYWHRHLIYLFQD---------KIN 968
Query: 349 EGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLL 408
E + LN + + Y+++ + + ++ A +Y QA+ +P D R G +
Sbjct: 969 EALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM 1028
Query: 409 QEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVL 467
E A + FS I ++P++ L R +N F A +D +L
Sbjct: 1029 YEITNKV--------LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALL 1079
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 22/154 (14%)
Query: 265 GKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVR 324
GKLQ A+ + R I PL + + R +Y + + A++D + + E +
Sbjct: 931 GKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLS 990
Query: 325 QAQRQLLLTYNDFAVHCYRQGAYQEGVLLLN--KALRDEQQEKGLYINRGDCFFQLGNLA 382
+A+ YR G + +LN +A++ + +Y RG+ +++ N
Sbjct: 991 KAE-------------IYR-GKKDITLAILNYTQAIKSTPTDADIYFRRGE-MYEITNKV 1035
Query: 383 FAEADYQQALALSPQDEGANTRMGLLQEKMGFCE 416
A D+ + + P+ A + GL +CE
Sbjct: 1036 LAIDDFSKCIFYDPKRTDALLKRGLF-----YCE 1064
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 53.1 bits (126), Expect = 1e-06
Identities = 60/262 (22%), Positives = 109/262 (41%), Gaps = 19/262 (7%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S +Y S + S T S + S+ +++S+S + +S S SG++
Sbjct: 202 SPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQ------HGSGSGHSS 255
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSK 722
HG R ++++G+R S + + S ++ H R S ++ + S R+ S
Sbjct: 256 GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG 315
Query: 723 T--RATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARG 780
+ ++ GQ S S ++G +S S + G + S + S K + G
Sbjct: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS------KHGSGSG 369
Query: 781 RSWRPSKVDATQGR--SRGLLRSSTKTEAFYDSNWSLSKTEYAQGQ---GQRSSKAEGAQ 835
S + +T G+ S G SS++ + Y + S S+ +GQ G S G +
Sbjct: 370 HSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQR 429
Query: 836 GKSQGMSSTSSKAESTWGPSPS 857
G G S +S + + +G S S
Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSS 451
Score = 52.0 bits (123), Expect = 2e-06
Identities = 71/315 (22%), Positives = 111/315 (35%), Gaps = 25/315 (7%)
Query: 567 GSSEGEAEAPEEEEEKEKEKKEEKKSELI---PSKVASLSDSYLDQTSSASSMSFRTTGT 623
GS + +EE++E EK+E K+ E S A +DSY + +
Sbjct: 98 GSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISR 157
Query: 624 SETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLS 683
+ ++ S S + ++ + + QSS G P + G QS S
Sbjct: 158 RLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSS 217
Query: 684 KTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQ-----GQSSSKTEA 738
+ S ++ ++SS + SQ + S + GQ GQSS
Sbjct: 218 ----NDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 273
Query: 739 TQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGL 798
SSS + G RQ + RQ P V+ G S G S
Sbjct: 274 RSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSY 333
Query: 799 LR-----SSTKTEAF----YDSNWSLSKTEYAQGQGQRSSKAE----GAQGKSQGMSSTS 845
R S +T F S S +++ G G SS+ + Q S G +S
Sbjct: 334 SRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSS 393
Query: 846 SKAESTWGPSPSLSK 860
S+ S++G S S+
Sbjct: 394 SRQSSSYGQHESASR 408
Score = 48.9 bits (115), Expect = 2e-05
Identities = 62/278 (22%), Positives = 107/278 (38%), Gaps = 25/278 (8%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S Y SS+ S S + S+ C ++ ++S + + +QSS G
Sbjct: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1589
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSS---------KTKATIHKRNSSKTKAT 713
P + G RQS S R+SS ++ H +SS ++
Sbjct: 1590 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1649
Query: 714 QSQRRNSSKTRATQGQGQSSSKT-EATQGQRQSSSEIEATQ------GPRQEPSKTKTTR 766
SQ + S + + G GQ S++ ++++G+R SS +++ G RQ +
Sbjct: 1650 YSQ--HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGS 1707
Query: 767 SPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDS------NWSLSKTEY 820
Q P + + G S G R R ++ + + S + S + Y
Sbjct: 1708 GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAY 1767
Query: 821 AQ-GQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
+Q G G ++G G + G SST + S+ G S S
Sbjct: 1768 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/213 (23%), Positives = 82/213 (38%), Gaps = 10/213 (4%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G+R S + + S ++ H ++
Sbjct: 1411 SSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHG 1470
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + Q + S+ R G GQSSS + G SSS +GP + S +
Sbjct: 1471 SGS----GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS-----RGPYESGSSHSSGLG 1521
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
R+ + G+ S +T G+ G + + + ++ S + G G
Sbjct: 1522 HRESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSK 860
S G QG G S + S SPS +
Sbjct: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613
Score = 47.8 bits (112), Expect = 5e-05
Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 12/210 (5%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G+R S ++ + S +++ H R
Sbjct: 1647 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQG 1706
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + + S+ R+ S G G SSS GQ S S +++GP + S +
Sbjct: 1707 SGSGQSPSRGRHGS------GLGHSSS-----HGQHGSGSGRSSSRGPYESRSGHSSVFG 1755
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
+ +A + S +QG+ G + T S+ S + G G
Sbjct: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQ-HGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 1814
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S + G QG G S + + S G S S
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
Score = 47.8 bits (112), Expect = 5e-05
Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 12/210 (5%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G+R S ++ + S +++ H R
Sbjct: 2117 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQG 2176
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + + S+ R+ S G G SSS GQ S S +++GP + S +
Sbjct: 2177 SGSGHSPSRGRHGS------GSGHSSS-----HGQHGSGSGRSSSRGPYESRSGHSSVFG 2225
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
+ +A + S +QG+ G + T S+ S + G G
Sbjct: 2226 QHESGSGHSSAYSQHGSGSGHFCSQGQ-HGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 2284
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S + G QG G S + + S G S S
Sbjct: 2285 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 2314
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/263 (23%), Positives = 88/263 (33%), Gaps = 13/263 (4%)
Query: 606 YLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREAL 665
Y S++ S + S + S+ ++ S+S + ++ +S G +
Sbjct: 828 YSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGS 887
Query: 666 SHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRA 725
P + G QS S R+SS + SS S ++S T+
Sbjct: 888 GQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQH 947
Query: 726 TQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRP 785
G G SSS + QSS + S + RQ + G P
Sbjct: 948 GSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1007
Query: 786 SKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRS-----------SKAEGA 834
S G G +SS+ S WS S+ Y G G S S G
Sbjct: 1008 SPSRGRHGSGSG--QSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 1065
Query: 835 QGKSQGMSSTSSKAESTWGPSPS 857
G S G SST + ST G S S
Sbjct: 1066 HGSSSGHSSTHGQHGSTSGQSSS 1088
Score = 47.4 bits (111), Expect = 6e-05
Identities = 62/278 (22%), Positives = 105/278 (37%), Gaps = 25/278 (8%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S Y SS+ S S + S+ C ++ ++S + + +QSS G
Sbjct: 2470 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2529
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSS---------KTKATIHKRNSSKTKAT 713
P + G RQS S R+SS ++ H +SS ++
Sbjct: 2530 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 2589
Query: 714 QSQRRNSSKTRATQGQGQSSSKT-EATQGQRQSSSEIEAT------QGPRQEPSKTKTTR 766
SQ + S + + G GQ S++ ++++G+R SS ++ G RQ +
Sbjct: 2590 YSQ--HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 2647
Query: 767 SPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDS------NWSLSKTEY 820
Q P + + G S G R R ++ + S + S + Y
Sbjct: 2648 GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAY 2707
Query: 821 AQ-GQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
+Q G G ++G G + G SST + S+ G S S
Sbjct: 2708 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2745
Score = 47.0 bits (110), Expect = 8e-05
Identities = 61/278 (21%), Positives = 106/278 (38%), Gaps = 25/278 (8%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S Y SS+ S S + S+ C ++ ++S + + +QSS G
Sbjct: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSS---------KTKATIHKRNSSKTKAT 713
P + G RQS S R+SS ++ H +SS ++
Sbjct: 2060 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
Query: 714 QSQRRNSSKTRATQGQGQSSSKT-EATQGQRQSSSEIEATQ------GPRQEPSKTKTTR 766
SQ + S + + G GQ S++ ++++G+R SS +++ G RQ +
Sbjct: 2120 YSQ--HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGS 2177
Query: 767 SPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDS------NWSLSKTEY 820
P + + G S G R R ++ + + S + S + Y
Sbjct: 2178 GSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAY 2237
Query: 821 AQ-GQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
+Q G G ++G G + G SST + S+ G S S
Sbjct: 2238 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
Score = 47.0 bits (110), Expect = 8e-05
Identities = 49/213 (23%), Positives = 82/213 (38%), Gaps = 10/213 (4%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G+R S + + S ++ H ++
Sbjct: 2351 SSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHG 2410
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + Q + S+ R G GQSSS + G SSS +GP + S +
Sbjct: 2411 SGS----GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS-----RGPYESGSGHSSGLG 2461
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
R+ + G+ S +T G+ G + + + ++ S + G G
Sbjct: 2462 HRESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 2520
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSK 860
S G QG G S + S SPS +
Sbjct: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2553
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/210 (23%), Positives = 82/210 (39%), Gaps = 10/210 (4%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G+RQ S + + S ++ H R+
Sbjct: 475 SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHG 534
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + Q + S+ R G QSSS G +SSS +GP + S +
Sbjct: 535 SGS----GQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSS-----RGPYESGSGHSSGLG 585
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
++ + G+ S +T G+ G + + + + S + G G
Sbjct: 586 HQESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S G QG G S + + S +G S S
Sbjct: 645 QSSRYGQQGSGSGQSPSRGRHGSDFGHSSS 674
Score = 46.2 bits (108), Expect = 1e-04
Identities = 61/266 (22%), Positives = 105/266 (39%), Gaps = 19/266 (7%)
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGP 669
+ S+ S +R G S + S+ +++ S+S + ++ QSS G H P
Sbjct: 718 SGSSHSSGYRKHG-SRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSP 776
Query: 670 RKIKATQGQRQSLSKTEPTQSQRRNSS-------KTKATIHKRNSSKTKATQSQRRNSSK 722
+++ S S + +SS +A+ ++ S + SQ ++S
Sbjct: 777 SRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASG 836
Query: 723 TRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPR-----QRPRKVKA 777
++QG+ S+S ++ GQ SSS ++ G + S + R Q P +
Sbjct: 837 HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQR 896
Query: 778 ARGRSWRPS--KVDATQGRSRGLLR---SSTKTEAFYDSNWSLSKTEYAQ-GQGQRSSKA 831
G PS + + GRS R S ++ F + S + Y Q G G S +
Sbjct: 897 GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
Query: 832 EGAQGKSQGMSSTSSKAESTWGPSPS 857
G G SS S + S+ G S S
Sbjct: 957 YEQHGSRSGQSSRSEQHGSSSGSSSS 982
Score = 46.2 bits (108), Expect = 1e-04
Identities = 61/278 (21%), Positives = 105/278 (37%), Gaps = 25/278 (8%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S Y SS+ S S + S+ C ++ ++S + + +QSS G
Sbjct: 1060 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1119
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSS---------KTKATIHKRNSSKTKAT 713
P + G RQS S R+SS ++ H +SS ++
Sbjct: 1120 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1179
Query: 714 QSQRRNSSKTRATQGQGQSSSKT-EATQGQRQSSSEIEAT------QGPRQEPSKTKTTR 766
SQ + S + + G GQ S++ ++++G+R SS ++ G RQ +
Sbjct: 1180 YSQ--HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 1237
Query: 767 SPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDS------NWSLSKTEY 820
P + + G S G R R ++ + + S + S + Y
Sbjct: 1238 GSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAY 1297
Query: 821 AQ-GQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
+Q G G ++G G + G SST + S+ G S S
Sbjct: 1298 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1335
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 10/213 (4%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G++ S + + S ++ H ++
Sbjct: 1881 SSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHG 1940
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + Q + S+ R G GQSSS G SSS +GP + S +
Sbjct: 1941 SGS----GQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSS-----RGPYESGSGHSSGLG 1991
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
R+ + G+ S +T G+ G + + + ++ S + G G
Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQ-HGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSK 860
S G QG G S + S SPS +
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2083
Score = 44.3 bits (103), Expect = 5e-04
Identities = 63/283 (22%), Positives = 96/283 (33%), Gaps = 35/283 (12%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S SY S + S S + S+ + + S+S ++ + QSS G
Sbjct: 2117 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQG 2176
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSK---------TKATIHKRNSSKTKAT 713
H P + + G S S + R+SS+ + + S +
Sbjct: 2177 SGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSA 2236
Query: 714 QSQRRNSSKTRATQGQ------------------GQSSSKTEATQGQRQSSSEIEATQGP 755
SQ + S +QGQ GQSSS + G QSSS + G
Sbjct: 2237 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 2296
Query: 756 RQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNW-S 814
Q PS+ + + G W ++ GR S+ S+W S
Sbjct: 2297 GQSPSRGRHGSGSGHSSSYGQHGSGSGW-----SSSSGRHGSGSGQSSGFGHHESSSWQS 2351
Query: 815 LSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
T++ G G SS + G G SS + S+ G S S
Sbjct: 2352 SGYTQHGSGSGHSSSYEQ--HGSRSGQSSRGERHGSSSGSSSS 2392
Score = 43.9 bits (102), Expect = 7e-04
Identities = 67/278 (24%), Positives = 103/278 (37%), Gaps = 36/278 (12%)
Query: 609 QTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHG 668
++ S S + G+ S+ Q + STS A + QSS G + A H
Sbjct: 352 ESGSGQSSGYSKHGSGSGHSSSQGQ-HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHS 410
Query: 669 PRKIKATQG--------QRQSLSKTEPTQSQR-----RNSSK---------TKATIHKRN 706
+ + + G QR S S P+ Q R+SS + H +
Sbjct: 411 SGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHES 470
Query: 707 SSKTKATQSQRRNSSKTRATQGQGQSSSKT-EATQGQRQSSSEIEATQ------GPRQEP 759
SS+ + +Q + S + + G GQ S++ ++++G+RQ SS ++ G RQ
Sbjct: 471 SSEHSSGYTQ--HGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
Query: 760 SKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTE 819
++ Q P + R S G G S E+ + L E
Sbjct: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQE 588
Query: 820 YAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
GQ S G G S G SST + ST G S S
Sbjct: 589 SRSGQ----SSGYGQHGSSSGHSSTHGQHGSTSGQSSS 622
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/213 (21%), Positives = 82/213 (38%), Gaps = 10/213 (4%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++ ++ S + + S ++ H ++
Sbjct: 941 SSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHG 1000
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + Q + S+ R G GQSSS G +S S +++GP + S +
Sbjct: 1001 SGS----GQSPSPSRGRHGSGSGQSSS-----YGPYRSGSGWSSSRGPYESGSGHSSGLG 1051
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
R+ + G+ S +T G+ G + + + ++ S + G G
Sbjct: 1052 HRESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1110
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSK 860
S G QG G S + S SPS +
Sbjct: 1111 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1143
Score = 43.1 bits (100), Expect = 0.001
Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 12/210 (5%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G+R S + + S +++ H R
Sbjct: 1177 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG 1236
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + + S+ R+ S G G SSS GQ S S +++GP + S +
Sbjct: 1237 SGSGHSPSRGRHGS------GLGHSSS-----HGQHGSGSGRSSSRGPYESRSGHSSVFG 1285
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
+ +A + S +QG+ G + T S+ S + +G G
Sbjct: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQ-HGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S G G G S + + S G S S
Sbjct: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSS 1374
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/276 (21%), Positives = 91/276 (32%), Gaps = 21/276 (7%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S Y S + S S + S+ + +RS+S ++ ++ QS G
Sbjct: 241 SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQ---------RRNSSKTKATIHKRNSSKTKAT 713
P ++ G S S + S +T + S +
Sbjct: 301 SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
Query: 714 QSQRRNSSKTRATQGQ-----GQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSP 768
S+ + S ++QGQ GQ+SS + RQSSS + R + + +
Sbjct: 361 YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS 420
Query: 769 RQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNW------SLSKTEYAQ 822
Q P + G PS G R + + Y S + S + Y Q
Sbjct: 421 GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ 480
Query: 823 -GQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
G G S G G G SS + S+ G S S
Sbjct: 481 HGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSS 516
Score = 41.2 bits (95), Expect = 0.004
Identities = 48/210 (22%), Positives = 80/210 (38%), Gaps = 12/210 (5%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S SG++ HG R ++++G+R S + + S +++ H R
Sbjct: 2587 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG 2646
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRS 767
S + + S+ R+ S G G SSS GQ S S +++GP + +
Sbjct: 2647 SGSGQSPSRGRHGS------GLGHSSS-----HGQHGSGSGRSSSRGPYESRLGHSSVFG 2695
Query: 768 PRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
+ +A + S +QG+ G + T S+ S + +G G
Sbjct: 2696 QHESGSGHSSAYSQHGSGSGHFCSQGQ-HGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 2754
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S G G G S + + S G S S
Sbjct: 2755 QSSGYGRHGAGSGQSLSHGRHGSGSGQSSS 2784
Score = 40.4 bits (93), Expect = 0.007
Identities = 61/271 (22%), Positives = 100/271 (36%), Gaps = 37/271 (13%)
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGP 669
+ S S S+ G S + S+ +++ S+S ++ ++ QS G + P
Sbjct: 949 SGSGHSSSYEQHG-SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1007
Query: 670 RKIKATQGQRQSLSKTE-PTQS----------QRRNSSKTKATIHKRNSSKTKATQSQRR 718
+ G S + P +S S + H+ + S + Q
Sbjct: 1008 SPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 1067
Query: 719 NSSKTRATQGQ------------------GQSSSKTEATQGQRQSSSEIEATQGPRQEPS 760
+SS +T GQ GQSSS + G QSS G Q P
Sbjct: 1068 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1127
Query: 761 KTKTTRSPRQRPR--KVKAARGRSWRPSKVDATQGRSRGL--LRSSTKTEAFYDSNWSLS 816
+ RQ P + + GRS + + G S G SS+ + Y + S S
Sbjct: 1128 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 1187
Query: 817 KTEYAQGQGQRSSKA-EGAQGKSQGMSSTSS 846
++ G GQ S++ + ++G+ G SS SS
Sbjct: 1188 --GHSSGYGQHGSRSGQSSRGERHGSSSGSS 1216
Score = 40.4 bits (93), Expect = 0.007
Identities = 60/271 (22%), Positives = 97/271 (35%), Gaps = 37/271 (13%)
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGP 669
+ S S S+ G S + S+ + + S+S ++ ++ QS G + P
Sbjct: 1419 SGSGHSSSYEQHG-SRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1477
Query: 670 RKIKATQGQRQSLSKTEPTQSQ-----------RRNSSKTKATIHKRNSSKTKATQSQRR 718
+ G S + SS + H+ + S + Q
Sbjct: 1478 SPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHG 1537
Query: 719 NSSKTRATQGQ------------------GQSSSKTEATQGQRQSSSEIEATQGPRQEPS 760
+SS +T GQ GQSSS + G QSS G Q P
Sbjct: 1538 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1597
Query: 761 KTKTTRSPRQRPR--KVKAARGRSWRPSKVDATQGRSRGL--LRSSTKTEAFYDSNWSLS 816
+ RQ P + + GRS + + G S G SS+ + Y + S S
Sbjct: 1598 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 1657
Query: 817 KTEYAQGQGQRSSKA-EGAQGKSQGMSSTSS 846
++ G GQ S++ + ++G+ G SS SS
Sbjct: 1658 --GHSSGYGQHGSRSGQSSRGERHGSSSRSS 1686
Score = 40.4 bits (93), Expect = 0.007
Identities = 62/273 (22%), Positives = 99/273 (36%), Gaps = 54/273 (19%)
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQS-------SDSGNNR 662
++S S +F G+S T S+ ++ S S+ + ++ QS S SG++
Sbjct: 2255 STSGQSSTFDQEGSS-TGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 2313
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSK 722
HG ++ R + + SS +++ + ++ S + + S ++ S+
Sbjct: 2314 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSR 2373
Query: 723 T-------RATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV 775
+ R G SSS + G RQS + G Q PS
Sbjct: 2374 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS--------------- 2418
Query: 776 KAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRS------- 828
+RGR G +SS+ + S WS S+ Y G G S
Sbjct: 2419 -PSRGR------------HGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRES 2465
Query: 829 ----SKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S G G S G SST + ST G S S
Sbjct: 2466 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 2498
Score = 39.3 bits (90), Expect = 0.016
Identities = 61/268 (22%), Positives = 104/268 (38%), Gaps = 29/268 (10%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S S+ S + S R S + S++ ++ S S + +S S SG+
Sbjct: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ------HGSGSGHFC 1308
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRR---- 718
HG +++ ++ S + + R S ++++ + R+ + + + S+ R
Sbjct: 1309 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSG 1368
Query: 719 ---NSSKTRATQGQGQSSSKTEATQGQRQSS------SEIEATQGPRQEPSKTKTTRSPR 769
+SS + G G SSS G QSS S + G Q S + + S
Sbjct: 1369 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYE 1428
Query: 770 QRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSS 829
Q + G+S R + ++ G SS+ + S SL ++ G GQ S
Sbjct: 1429 QHGSR----SGQSSRGERHGSSSG------SSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1478
Query: 830 KAEGAQGKSQGMSSTSSKAESTWGPSPS 857
+ G G G SS+ S S G S S
Sbjct: 1479 PSRGRHGSGSGQSSSYSPYGSGSGWSSS 1506
Score = 38.9 bits (89), Expect = 0.021
Identities = 54/232 (23%), Positives = 91/232 (39%), Gaps = 27/232 (11%)
Query: 656 SDSGNNREALSHGP-RKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS-SKTKAT 713
S SG++ HG ++G +S S Q + S + K S S ++
Sbjct: 314 SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSS 373
Query: 714 QSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPR-----QEPSKTKTTRSP 768
Q Q ++S ++ GQ SSS+ ++ GQ +S+S + +G Q P +
Sbjct: 374 QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGS 433
Query: 769 RQRPRKVKAARG--RSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQ 826
Q P + G RS + G S G + +E S + ++ G GQ
Sbjct: 434 GQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQ 493
Query: 827 RSSKA-EGAQGKSQGMSSTSSKAE-----------------STWGPSPSLSK 860
S++ + ++G+ QG S+ SS + S G SPS S+
Sbjct: 494 HGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSR 545
Score = 38.9 bits (89), Expect = 0.021
Identities = 59/271 (21%), Positives = 97/271 (35%), Gaps = 37/271 (13%)
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGP 669
+ S S S+ G S + S+ + + S+S ++ ++ QS G + P
Sbjct: 2359 SGSGHSSSYEQHG-SRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 2417
Query: 670 RKIKATQGQRQSLSKTEPTQSQRRNSSKTKATI-----------HKRNSSKTKATQSQRR 718
+ G S + S ++ H+ + S + Q
Sbjct: 2418 SPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 2477
Query: 719 NSSKTRATQGQ------------------GQSSSKTEATQGQRQSSSEIEATQGPRQEPS 760
+SS +T GQ GQSSS + G QSS G Q P
Sbjct: 2478 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 2537
Query: 761 KTKTTRSPRQRPR--KVKAARGRSWRPSKVDATQGRSRGL--LRSSTKTEAFYDSNWSLS 816
+ RQ P + + GRS + + G S G SS+ + Y + S S
Sbjct: 2538 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 2597
Query: 817 KTEYAQGQGQRSSKA-EGAQGKSQGMSSTSS 846
++ G GQ S++ + ++G+ G SS SS
Sbjct: 2598 --GHSSGYGQHGSRSGQSSRGERHGSSSGSS 2626
Score = 38.5 bits (88), Expect = 0.027
Identities = 59/271 (21%), Positives = 97/271 (35%), Gaps = 37/271 (13%)
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGP 669
+ S S S+ G S + S+ +++ S+S ++ ++ QS G + P
Sbjct: 1889 SGSGHSSSYEQHG-SRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1947
Query: 670 RKIKATQGQRQSLSKTEPTQSQRRNSSKTKATI-----------HKRNSSKTKATQSQRR 718
+ G S + S ++ H+ + S + Q
Sbjct: 1948 SPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 2007
Query: 719 NSSKTRATQGQ------------------GQSSSKTEATQGQRQSSSEIEATQGPRQEPS 760
+SS +T GQ GQSSS + G QSS G Q P
Sbjct: 2008 SSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 2067
Query: 761 KTKTTRSPRQRPR--KVKAARGRSWRPSKVDATQGRSRGL--LRSSTKTEAFYDSNWSLS 816
+ RQ P + + GRS + G S G SS+ + Y + S S
Sbjct: 2068 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGS 2127
Query: 817 KTEYAQGQGQRSSKA-EGAQGKSQGMSSTSS 846
++ G GQ S++ + ++G+ G SS SS
Sbjct: 2128 --GHSSGYGQHGSRSGQSSRGERHGSSSGSS 2156
Score = 38.1 bits (87), Expect = 0.036
Identities = 49/213 (23%), Positives = 82/213 (38%), Gaps = 6/213 (2%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRK-IKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRN 706
SS L Q S SG + HG +T GQ S S + Q +S ++ +
Sbjct: 581 SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHG 640
Query: 707 SSKTKATQ-SQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTT 765
S +++++ Q+ + S ++G+ S ++ GQ S S ++ GP S +
Sbjct: 641 SGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSG 700
Query: 766 RSPRQRPRKVKAARGRSWRPSKVDATQG-RSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQ 824
+ + + G S S + G R G + + S+ LS + G
Sbjct: 701 FGHKSGSGQ---SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGS 757
Query: 825 GQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
G S G QG G S + + S+ G S S
Sbjct: 758 GSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSS 790
Score = 37.4 bits (85), Expect = 0.061
Identities = 61/273 (22%), Positives = 102/273 (37%), Gaps = 54/273 (19%)
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQS-------SDSGNNR 662
++S S +F G+S T S+ ++ S S+ + ++ QS S SG++
Sbjct: 1785 STSGQSSTFDQEGSS-TGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 1843
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSK 722
HG ++ R + + SS +++ + ++ S + + S ++ S+
Sbjct: 1844 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSR 1903
Query: 723 T-RATQGQ------GQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV 775
+ ++++G+ G SSS + G RQS + G Q PS
Sbjct: 1904 SGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS--------------- 1948
Query: 776 KAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRS------- 828
+RGR G +SS+ S WS S+ Y G G S
Sbjct: 1949 -PSRGR------------HGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES 1995
Query: 829 ----SKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S G G S G SST + S G S S
Sbjct: 1996 RSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSS 2028
Score = 37.0 bits (84), Expect = 0.080
Identities = 61/269 (22%), Positives = 102/269 (37%), Gaps = 31/269 (11%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S S+ S + S R S + S++ ++ S S + +S S SG+
Sbjct: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ------HGSGSGHFC 1778
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRR---- 718
HG +++ ++ S + + + S ++++ + + S + + S+ R
Sbjct: 1779 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 1838
Query: 719 ---NSSKTRATQGQGQSSSKTEATQGQRQSS------SEIEATQGPRQEPSKTKTTRSPR 769
+SS + G G SSS G QSS S + G Q S + + S
Sbjct: 1839 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYE 1898
Query: 770 QR-PRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRS 828
Q R +++RG G S G SS+ + S SL ++ G GQ
Sbjct: 1899 QHGSRSGQSSRGEQ---------HGSSSG--SSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1947
Query: 829 SKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S + G G G SS+ S G S S
Sbjct: 1948 SPSRGRHGSGSGQSSSYGPYGSGSGWSSS 1976
Score = 36.6 bits (83), Expect = 0.10
Identities = 45/220 (20%), Positives = 84/220 (38%), Gaps = 12/220 (5%)
Query: 648 SSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNS 707
SS S S ++ HG R ++++ ++ S + + S +++ H R
Sbjct: 710 SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQG 769
Query: 708 SKTKATQSQRRNSSKTRATQGQGQSSSKTEAT-------QGQRQSSSEIEATQGPRQEPS 760
S + + S+ R+ S + + GQ S T + G Q+S + G Q S
Sbjct: 770 SGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYS 829
Query: 761 KTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEY 820
+ + + + G+S + D++ G+S + + + S +
Sbjct: 830 QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ 889
Query: 821 AQGQGQR-----SSKAEGAQGKSQGMSSTSSKAESTWGPS 855
+ G GQR S + G G G SS+S + S G S
Sbjct: 890 SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQS 929
Score = 34.7 bits (78), Expect = 0.40
Identities = 48/204 (23%), Positives = 79/204 (38%), Gaps = 14/204 (6%)
Query: 656 SDSGNNREALSHGPRK-IKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQ 714
S SG++ HG ++ G+ S S +SS + + S ++
Sbjct: 1367 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSS 1426
Query: 715 SQRRNSSKTRATQGQGQ-SSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPR 773
++ S ++++G+ SSS + ++ GQ S S + G Q S + + SP +
Sbjct: 1427 YEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRH 1484
Query: 774 KVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEG 833
+ + S+ P + SRG S + + L E GQ S G
Sbjct: 1485 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSS------GLGHRESRSGQ----SSGYG 1534
Query: 834 AQGKSQGMSSTSSKAESTWGPSPS 857
G S G SST + ST G S S
Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSS 1558
Score = 30.4 bits (67), Expect = 7.5
Identities = 34/156 (21%), Positives = 63/156 (40%), Gaps = 12/156 (7%)
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR 662
S S+ S + S R S S++ ++ S S + +S S SG+
Sbjct: 2665 SSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQ------HGSGSGHFC 2718
Query: 663 EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSK 722
HG +++ ++ S + + R S ++++ + R+ + + + S R+ S
Sbjct: 2719 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGS- 2777
Query: 723 TRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQE 758
G GQSSS + G QSS + G Q+
Sbjct: 2778 -----GSGQSSSYGQHGSGSGQSSGYSQHGSGSGQD 2808
>gi|188497758 ubiquitin associated protein 2-like isoform a [Homo
sapiens]
Length = 1087
Score = 53.1 bits (126), Expect = 1e-06
Identities = 59/277 (21%), Positives = 122/277 (44%), Gaps = 31/277 (11%)
Query: 504 QLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGEPLIATSEELKATPE--- 560
Q +V+ L+ S + + + + ++ ++ P +ATS P
Sbjct: 397 QSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPL 456
Query: 561 ------IPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSAS 614
PQ+ PGSS+ ++ +P+ ++K K++KK + SK+ +L+ + ++ S
Sbjct: 457 PSKSTSAPQMSPGSSDNQSSSPQPAQQK---LKQQKKKASLTSKIPALAVE-MPGSADIS 512
Query: 615 SMSFRTTGTSETEMSAICQEYRSTSATAVTFSD--SSLLKTQSSDSGNNREALSHGPRKI 672
++ + G + + +Y ST T+ + S SSL + +S+S + I
Sbjct: 513 GLNLQ-FGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSST----------I 561
Query: 673 KATQGQRQSLSKTEPTQSQRRNS-SKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQ 731
+ Q Q +S ++ P QS S + + ++++ S++T+ S +S + TQ +
Sbjct: 562 SSNQSQ-ESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNG 620
Query: 732 SSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSP 768
SS +AT Q Q++ +E G + T+ P
Sbjct: 621 FSS-VQAT--QLQTTQSVEGATGSAVKSDSPSTSSIP 654
>gi|188497756 ubiquitin associated protein 2-like isoform b [Homo
sapiens]
Length = 983
Score = 53.1 bits (126), Expect = 1e-06
Identities = 59/277 (21%), Positives = 122/277 (44%), Gaps = 31/277 (11%)
Query: 504 QLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGEPLIATSEELKATPE--- 560
Q +V+ L+ S + + + + ++ ++ P +ATS P
Sbjct: 397 QSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPL 456
Query: 561 ------IPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSAS 614
PQ+ PGSS+ ++ +P+ ++K K++KK + SK+ +L+ + ++ S
Sbjct: 457 PSKSTSAPQMSPGSSDNQSSSPQPAQQK---LKQQKKKASLTSKIPALAVE-MPGSADIS 512
Query: 615 SMSFRTTGTSETEMSAICQEYRSTSATAVTFSD--SSLLKTQSSDSGNNREALSHGPRKI 672
++ + G + + +Y ST T+ + S SSL + +S+S + I
Sbjct: 513 GLNLQ-FGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSST----------I 561
Query: 673 KATQGQRQSLSKTEPTQSQRRNS-SKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQ 731
+ Q Q +S ++ P QS S + + ++++ S++T+ S +S + TQ +
Sbjct: 562 SSNQSQ-ESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNG 620
Query: 732 SSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSP 768
SS +AT Q Q++ +E G + T+ P
Sbjct: 621 FSS-VQAT--QLQTTQSVEGATGSAVKSDSPSTSSIP 654
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 52.8 bits (125), Expect = 1e-06
Identities = 63/255 (24%), Positives = 112/255 (43%), Gaps = 15/255 (5%)
Query: 547 PLIATS---EELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLS 603
PL+A+ + A+P + + +SE +E ++ E K K +KS+ +K
Sbjct: 1755 PLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSK--KNKNRDKG 1812
Query: 604 DSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNRE 663
+ + SS S S R+ +SE + E RS + + S S +T+S R
Sbjct: 1813 EKEKKRDSSLRSRSKRSK-SSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 664 ALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKT 723
S K + R+S+SK + +S + S K++ KR+SS+ + R+ + +
Sbjct: 1872 RSSRSRSKSRG----RRSVSKEKRKRSPKHRS-KSRERKRKRSSSRDNRKTVRARSRTPS 1926
Query: 724 RATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRP--RKVKAARGR 781
R ++ S + + G+R+S S + + + PS+ T S R R R+ + R
Sbjct: 1927 RRSRSHTPSRRRRSRSVGRRRSFSISPSRRS--RTPSRRSRTPSRRSRTPSRRSRTPSRR 1984
Query: 782 SWRPSKVDATQGRSR 796
S PS+ T R R
Sbjct: 1985 SRTPSRRSRTPSRRR 1999
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 4/132 (3%)
Query: 671 KIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQG 730
K K + + + + + S R S ++K++ HK +++ R+ SSK+++ + Q
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT 1861
Query: 731 QSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDA 790
+S S++ +R+ SS + R+ SK K RSP+ R + + R RS
Sbjct: 1862 RSRSRSR----RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT 1917
Query: 791 TQGRSRGLLRSS 802
+ RSR R S
Sbjct: 1918 VRARSRTPSRRS 1929
Score = 44.3 bits (103), Expect = 5e-04
Identities = 54/223 (24%), Positives = 91/223 (40%), Gaps = 8/223 (3%)
Query: 565 KPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTS 624
K S E + + +K KS+ S+ S S S + SS S R +
Sbjct: 1827 KRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSV 1886
Query: 625 ETEMSAICQEYRSTSATAVTFSDSSL--LKTQSSDSGN-NREALSHGP--RKIKATQGQR 679
E ++RS S SS KT + S +R + SH P R+ + G+R
Sbjct: 1887 SKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRR 1946
Query: 680 QSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEAT 739
+S S + +S+ + + R S+ T S+R S+T + + + S + +
Sbjct: 1947 RSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR---SRTPSRRSRTPSRRRRSRS 2003
Query: 740 QGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRS 782
+R+S S + P + + +RSP +R R + RGRS
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 30.8 bits (68), Expect = 5.7
Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 13/90 (14%)
Query: 552 SEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVAS--------LS 603
S + T EIP K + + +++++KEKEKK +++ E SK S S
Sbjct: 94 SVQTDPTDEIP-TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLES 152
Query: 604 DSYLDQTSSASSMSF----RTTGTSETEMS 629
DS+L S S+++ R G SET S
Sbjct: 153 DSFLKFDSEPSAVALELPTRAFGPSETNES 182
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 52.8 bits (125), Expect = 1e-06
Identities = 63/255 (24%), Positives = 112/255 (43%), Gaps = 15/255 (5%)
Query: 547 PLIATS---EELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLS 603
PL+A+ + A+P + + +SE +E ++ E K K +KS+ +K
Sbjct: 1755 PLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSK--KNKNRDKG 1812
Query: 604 DSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNRE 663
+ + SS S S R+ +SE + E RS + + S S +T+S R
Sbjct: 1813 EKEKKRDSSLRSRSKRSK-SSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 664 ALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKT 723
S K + R+S+SK + +S + S K++ KR+SS+ + R+ + +
Sbjct: 1872 RSSRSRSKSRG----RRSVSKEKRKRSPKHRS-KSRERKRKRSSSRDNRKTVRARSRTPS 1926
Query: 724 RATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRP--RKVKAARGR 781
R ++ S + + G+R+S S + + + PS+ T S R R R+ + R
Sbjct: 1927 RRSRSHTPSRRRRSRSVGRRRSFSISPSRRS--RTPSRRSRTPSRRSRTPSRRSRTPSRR 1984
Query: 782 SWRPSKVDATQGRSR 796
S PS+ T R R
Sbjct: 1985 SRTPSRRSRTPSRRR 1999
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 4/132 (3%)
Query: 671 KIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQG 730
K K + + + + + S R S ++K++ HK +++ R+ SSK+++ + Q
Sbjct: 1802 KSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT 1861
Query: 731 QSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDA 790
+S S++ +R+ SS + R+ SK K RSP+ R + + R RS
Sbjct: 1862 RSRSRSR----RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT 1917
Query: 791 TQGRSRGLLRSS 802
+ RSR R S
Sbjct: 1918 VRARSRTPSRRS 1929
Score = 44.3 bits (103), Expect = 5e-04
Identities = 54/223 (24%), Positives = 91/223 (40%), Gaps = 8/223 (3%)
Query: 565 KPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTS 624
K S E + + +K KS+ S+ S S S + SS S R +
Sbjct: 1827 KRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSV 1886
Query: 625 ETEMSAICQEYRSTSATAVTFSDSSL--LKTQSSDSGN-NREALSHGP--RKIKATQGQR 679
E ++RS S SS KT + S +R + SH P R+ + G+R
Sbjct: 1887 SKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRR 1946
Query: 680 QSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEAT 739
+S S + +S+ + + R S+ T S+R S+T + + + S + +
Sbjct: 1947 RSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR---SRTPSRRSRTPSRRRRSRS 2003
Query: 740 QGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRS 782
+R+S S + P + + +RSP +R R + RGRS
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 30.8 bits (68), Expect = 5.7
Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 13/90 (14%)
Query: 552 SEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVAS--------LS 603
S + T EIP K + + +++++KEKEKK +++ E SK S S
Sbjct: 94 SVQTDPTDEIP-TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLES 152
Query: 604 DSYLDQTSSASSMSF----RTTGTSETEMS 629
DS+L S S+++ R G SET S
Sbjct: 153 DSFLKFDSEPSAVALELPTRAFGPSETNES 182
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 52.4 bits (124), Expect = 2e-06
Identities = 68/299 (22%), Positives = 117/299 (39%), Gaps = 33/299 (11%)
Query: 559 PEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSF 618
P Q + G+ + + E ++ S + K S ++ S S S
Sbjct: 792 PSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHS- 850
Query: 619 RTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQ 678
R+ S S+ RS S+++ SD S Q S S ++ S
Sbjct: 851 RSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYS---------DRS 901
Query: 679 RQSLSKTEPTQSQRRNSSKTKATIHKRNSS----KTKATQSQRRNSSKTR---ATQGQGQ 731
R+ ++ + SSK ++ HK +SS +QS+ R+ S TR ++G+ +
Sbjct: 902 RRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSR 961
Query: 732 SSSKTEATQGQRQSSSEIEATQGPRQ-EPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDA 790
SSS + + +R S+ + Q R ++++TRSP QR +R RSW +
Sbjct: 962 SSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQR----SGSRKRSWGHESPEE 1017
Query: 791 TQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQG---KSQGMSSTSS 846
R +RS S S + G+G+ K + +G K+ G S +S
Sbjct: 1018 RHSGRRDFIRSKIYR--------SQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNS 1068
Score = 43.1 bits (100), Expect = 0.001
Identities = 50/228 (21%), Positives = 90/228 (39%), Gaps = 36/228 (15%)
Query: 654 QSSDSGNNREALSHGPRKIKATQGQRQS-LSKTEPTQSQRRNSSKT------------KA 700
+S + G + S G R G S L+K EP S + T K+
Sbjct: 613 KSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKS 672
Query: 701 TIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQ----SSSEIEATQGPR 756
HK+ K+++ +R++ + T + +S K++ + +++ SS+ ++ +GP+
Sbjct: 673 HRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPK 732
Query: 757 QEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLS 816
EP + + PR+R R ++ RS + A +G S K E S+
Sbjct: 733 PEPPGSGSPAPPRRRRRAQDDSQRRS-----LPAEEG------SSGKKDEGGGGSS---- 777
Query: 817 KTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTEVD 864
+Q G R K E Q + T + S+ PS + D
Sbjct: 778 ----SQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSD 821
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 52.0 bits (123), Expect = 2e-06
Identities = 61/289 (21%), Positives = 122/289 (42%), Gaps = 12/289 (4%)
Query: 86 RALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCK---HLERLTFVLYLQ 142
+++ LD V + + +L L + +A ++ +RA L N + + V+ +
Sbjct: 31 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 90
Query: 143 --GQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQD 200
+ FE+ F + A E P F+ CL L ++ ++ ++ L+ D
Sbjct: 91 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD 150
Query: 201 TTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGI 260
+TNAD R + + AL + P H +A + + A+A +A+++ G
Sbjct: 151 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRN--AKALKAKKEDGN 208
Query: 261 LAV-QGKLQHALQRINRAIENNP----LDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMV 315
A +G + A + A+ +P + L+ RGT+ +L++ D A+ED + +
Sbjct: 209 KAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLD 268
Query: 316 TEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQE 364
+ +R+AQ + + AV Y + E + L++ Q E
Sbjct: 269 DTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLE 317
Score = 44.7 bits (104), Expect = 4e-04
Identities = 63/294 (21%), Positives = 109/294 (37%), Gaps = 45/294 (15%)
Query: 61 VREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDF---SSAAQN 117
V EY + E+ D+ V RAL P F L+AE L + S A +
Sbjct: 86 VMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASD 145
Query: 118 LRRAYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQP--EKPCFRYR 175
+ R S D LY++G CL+ + A+ F A + P EK C R
Sbjct: 146 ILRMDSTNAD----------ALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACR 195
Query: 176 CMACLLALKQ----------HQACLTLITNELKQD----TTNADVYIFRARLYNFLQKPH 221
L A K+ ++ L T L D TNA +Y R + + L+K
Sbjct: 196 NAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLD 255
Query: 222 LCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENN 281
D +A+ L+ + +A + + +Q + A++ + +
Sbjct: 256 DAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQ-------------YEEAVRDYEKVYQTE 302
Query: 282 PLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYN 335
L + +L+ +D+ K+L + ED +++A R+ L ++
Sbjct: 303 KTKEHKQLLKNA---QLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHH 353
Score = 32.3 bits (72), Expect = 2.0
Identities = 31/125 (24%), Positives = 52/125 (41%), Gaps = 13/125 (10%)
Query: 356 KALRDEQQEKGL-------YINRGDCFFQLGNLAFAEADYQQALAL-----SPQDEGANT 403
+AL D QQ L ++ G C LGN A +Q+AL L Q E N
Sbjct: 24 EALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNA 83
Query: 404 RMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDV 463
+ EK+ + ++ F+K A+ P ++ + +A+ +L + Q V
Sbjct: 84 NAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGR-YPEAQSV 142
Query: 464 ATVLL 468
A+ +L
Sbjct: 143 ASDIL 147
Score = 30.8 bits (68), Expect = 5.7
Identities = 70/310 (22%), Positives = 116/310 (37%), Gaps = 37/310 (11%)
Query: 295 YRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLL 354
Y ++ E D DF KV+ + E R +L A+ G Y E +
Sbjct: 89 YEKIAETDFEKRDFRKVVFCMDRALE-FAPACHRFKILKAECLAM----LGRYPEAQSVA 143
Query: 355 NKALR-DEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGA-----NTRMGLL 408
+ LR D LY+ RG C + + A + QAL ++P E A N +
Sbjct: 144 SDILRMDSTNADALYV-RGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKA 202
Query: 409 QEKMGFCEQRRKQFQKAENHFSTAIRHNPQ----KAQYYLYRAKSRQLLQNIFGARQDVA 464
+++ G + ++ A ++ A+ +P A+ Y R L+ + A +D
Sbjct: 203 KKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 262
Query: 465 TVLLLNPKQPKLSLLMTNLFPGMSVEEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGM 524
+ L+ K L + M E+ + Q E+ E +
Sbjct: 263 NAVKLDDTYIKAYLRRAQCY--MDTEQYEEAVRDYEKVYQTEKTKEHK----------QL 310
Query: 525 LKRHELERQKALALQHSWKQGEPLIATSEELK------ATPEIPQVKPGSSEGEAEAPEE 578
LK +LE +K+ + G A+ +E+K A P G+S AE +E
Sbjct: 311 LKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGAS---AEVQKE 367
Query: 579 EEEKEKEKKE 588
EE+K KE E
Sbjct: 368 EEKKFKEVGE 377
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 52.0 bits (123), Expect = 2e-06
Identities = 61/289 (21%), Positives = 122/289 (42%), Gaps = 12/289 (4%)
Query: 86 RALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCK---HLERLTFVLYLQ 142
+++ LD V + + +L L + +A ++ +RA L N + + V+ +
Sbjct: 87 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 146
Query: 143 --GQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQD 200
+ FE+ F + A E P F+ CL L ++ ++ ++ L+ D
Sbjct: 147 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD 206
Query: 201 TTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGI 260
+TNAD R + + AL + P H +A + + A+A +A+++ G
Sbjct: 207 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRN--AKALKAKKEDGN 264
Query: 261 LAV-QGKLQHALQRINRAIENNP----LDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMV 315
A +G + A + A+ +P + L+ RGT+ +L++ D A+ED + +
Sbjct: 265 KAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLD 324
Query: 316 TEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQE 364
+ +R+AQ + + AV Y + E + L++ Q E
Sbjct: 325 DTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLE 373
Score = 44.7 bits (104), Expect = 4e-04
Identities = 63/294 (21%), Positives = 109/294 (37%), Gaps = 45/294 (15%)
Query: 61 VREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDF---SSAAQN 117
V EY + E+ D+ V RAL P F L+AE L + S A +
Sbjct: 142 VMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASD 201
Query: 118 LRRAYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQP--EKPCFRYR 175
+ R S D LY++G CL+ + A+ F A + P EK C R
Sbjct: 202 ILRMDSTNAD----------ALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACR 251
Query: 176 CMACLLALKQ----------HQACLTLITNELKQD----TTNADVYIFRARLYNFLQKPH 221
L A K+ ++ L T L D TNA +Y R + + L+K
Sbjct: 252 NAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLD 311
Query: 222 LCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENN 281
D +A+ L+ + +A + + +Q + A++ + +
Sbjct: 312 DAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQ-------------YEEAVRDYEKVYQTE 358
Query: 282 PLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYN 335
L + +L+ +D+ K+L + ED +++A R+ L ++
Sbjct: 359 KTKEHKQLLKNA---QLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHH 409
Score = 35.8 bits (81), Expect = 0.18
Identities = 37/186 (19%), Positives = 76/186 (40%), Gaps = 18/186 (9%)
Query: 288 FLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAY 347
F +G Y ++++ A + K +DM ++ +A ++L G +
Sbjct: 31 FKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMML------------GRF 78
Query: 348 QEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALAL-----SPQDEGAN 402
+E + +++R + ++ G C LGN A +Q+AL L Q E N
Sbjct: 79 REALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKN 138
Query: 403 TRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQD 462
+ EK+ + ++ F+K A+ P ++ + +A+ +L + Q
Sbjct: 139 ANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGR-YPEAQS 197
Query: 463 VATVLL 468
VA+ +L
Sbjct: 198 VASDIL 203
Score = 32.3 bits (72), Expect = 2.0
Identities = 95/463 (20%), Positives = 166/463 (35%), Gaps = 79/463 (17%)
Query: 142 QGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDT 201
QG + + + +A N ++ A ++ P+ + A L+ L + + L ++ D
Sbjct: 34 QGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDD 93
Query: 202 TNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGIL 261
+ ++ + + L R AL L+ K+ AQAQQ ++A
Sbjct: 94 SFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKN-----------AQAQQEFKNA--- 139
Query: 262 AVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQED 321
N +E Y ++ E D DF KV+ + E
Sbjct: 140 -------------NAVME---------------YEKIAETDFEKRDFRKVVFCMDRALE- 170
Query: 322 MVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALR-DEQQEKGLYINRGDCFFQLGN 380
R +L A+ G Y E + + LR D LY+ RG C +
Sbjct: 171 FAPACHRFKILKAECLAM----LGRYPEAQSVASDILRMDSTNADALYV-RGLCLYYEDC 225
Query: 381 LAFAEADYQQALALSPQDEGA-----NTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRH 435
+ A + QAL ++P E A N + +++ G + ++ A ++ A+
Sbjct: 226 IEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGI 285
Query: 436 NPQ----KAQYYLYRAKSRQLLQNIFGARQDVATVLLLNPKQPKLSLLMTNLFPGMSVEE 491
+P A+ Y R L+ + A +D + L+ K L + M E+
Sbjct: 286 DPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCY--MDTEQ 343
Query: 492 VLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGEPLIAT 551
+ Q E+ E +LK +LE +K+ + G A+
Sbjct: 344 YEEAVRDYEKVYQTEKTKEHK----------QLLKNAQLELRKSKRKDYYKILGVDKNAS 393
Query: 552 SEELK------ATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKE 588
+E+K A P G+S AE +EEE+K KE E
Sbjct: 394 EDEIKKAYRKRALMHHPDRHSGAS---AEVQKEEEKKFKEVGE 433
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 51.6 bits (122), Expect = 3e-06
Identities = 70/362 (19%), Positives = 130/362 (35%), Gaps = 64/362 (17%)
Query: 143 GQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTT 202
G E+ +A+ + HA L+P+ A L+A + + + L+
Sbjct: 86 GNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQY--- 142
Query: 203 NADVYIFRARLYNFL------QKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQ 256
N D+Y R+ L N L ++ CY A+ P A L
Sbjct: 143 NPDLYCVRSDLGNLLKALGRLEEAKACYL---KAIETQPNFAVAWSNL------------ 187
Query: 257 DAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVT 316
+ QG++ A+ +A+ +P ++ G + + + FD AV +L+ L +
Sbjct: 188 -GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSP 246
Query: 317 EDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFF 376
+ + + A Y QG + +A+ + Y N +
Sbjct: 247 NHA------------VVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALK 294
Query: 377 QLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCE-------------------- 416
+ G++A AE Y AL L P + + ++ + G E
Sbjct: 295 EKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 354
Query: 417 -------QRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVLLL 469
Q++ + Q+A H+ AIR +P A Y + + +Q++ GA Q + +
Sbjct: 355 SNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 414
Query: 470 NP 471
NP
Sbjct: 415 NP 416
Score = 45.1 bits (105), Expect = 3e-04
Identities = 88/421 (20%), Positives = 154/421 (36%), Gaps = 55/421 (13%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQN 117
PL Y + G E+ + A+ + AL L P +D Y A A + D A Q
Sbjct: 76 PLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQA 135
Query: 118 LRRAYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCM 177
A D L +L G+ + +L A+ + A C
Sbjct: 136 YVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG 195
Query: 178 ACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHS---ALLLN 234
LA+ + +TL N L D YI L N L++ + R + + AL L+
Sbjct: 196 EIWLAIHHFEKAVTLDPNFL-------DAYI---NLGNVLKEARIFDRAVAAYLRALSLS 245
Query: 235 PKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLF---- 290
P H L A + QG + A+ RAIE P P +
Sbjct: 246 PNHAVVHGNL-------------ACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANA 292
Query: 291 ---RGTMYRRLQEFDGAVE------DFLKVLDMVTEDQ---EDMVRQAQRQLLL------ 332
+G++ ++ A+ D L L + +Q E+ VR ++ L +
Sbjct: 293 LKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAA 352
Query: 333 TYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQAL 392
+++ A +QG QE ++ +A+R Y N G+ ++ ++ A Y +A+
Sbjct: 353 AHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAI 412
Query: 393 ALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQL 452
++P A++ + + + G +A + TA++ P Y A Q+
Sbjct: 413 QINPAFADAHSNLASIHKDSG-------NIPEAIASYRTALKLKPDFPDAYCNLAHCLQI 465
Query: 453 L 453
+
Sbjct: 466 V 466
Score = 33.5 bits (75), Expect = 0.88
Identities = 45/203 (22%), Positives = 78/203 (38%), Gaps = 32/203 (15%)
Query: 252 QQARQDAGILAVQGKLQHALQRINR-------AIENNPLDPSLFLFRGTMYRRLQEFDGA 304
+Q + G+L + + +R++R AI+ NPL + G +Y+ + A
Sbjct: 39 RQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEA 98
Query: 305 VEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQE 364
+E + L + + + + A L+ D +GA Q V L Q
Sbjct: 99 IEHYRHALRLKPDFIDGYINLA--AALVAAGDM------EGAVQAYVSAL-------QYN 143
Query: 365 KGLYINR---GDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQ 421
LY R G+ LG L A+A Y +A+ P A + +G + G +
Sbjct: 144 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG-------E 196
Query: 422 FQKAENHFSTAIRHNPQKAQYYL 444
A +HF A+ +P Y+
Sbjct: 197 IWLAIHHFEKAVTLDPNFLDAYI 219
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 51.6 bits (122), Expect = 3e-06
Identities = 70/362 (19%), Positives = 130/362 (35%), Gaps = 64/362 (17%)
Query: 143 GQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTT 202
G E+ +A+ + HA L+P+ A L+A + + + L+
Sbjct: 96 GNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQY--- 152
Query: 203 NADVYIFRARLYNFL------QKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQ 256
N D+Y R+ L N L ++ CY A+ P A L
Sbjct: 153 NPDLYCVRSDLGNLLKALGRLEEAKACYL---KAIETQPNFAVAWSNL------------ 197
Query: 257 DAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVT 316
+ QG++ A+ +A+ +P ++ G + + + FD AV +L+ L +
Sbjct: 198 -GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSP 256
Query: 317 EDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFF 376
+ + + A Y QG + +A+ + Y N +
Sbjct: 257 NHA------------VVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALK 304
Query: 377 QLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCE-------------------- 416
+ G++A AE Y AL L P + + ++ + G E
Sbjct: 305 EKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 364
Query: 417 -------QRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVLLL 469
Q++ + Q+A H+ AIR +P A Y + + +Q++ GA Q + +
Sbjct: 365 SNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 424
Query: 470 NP 471
NP
Sbjct: 425 NP 426
Score = 45.1 bits (105), Expect = 3e-04
Identities = 88/421 (20%), Positives = 154/421 (36%), Gaps = 55/421 (13%)
Query: 58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQN 117
PL Y + G E+ + A+ + AL L P +D Y A A + D A Q
Sbjct: 86 PLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQA 145
Query: 118 LRRAYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCM 177
A D L +L G+ + +L A+ + A C
Sbjct: 146 YVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG 205
Query: 178 ACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHS---ALLLN 234
LA+ + +TL N L D YI L N L++ + R + + AL L+
Sbjct: 206 EIWLAIHHFEKAVTLDPNFL-------DAYI---NLGNVLKEARIFDRAVAAYLRALSLS 255
Query: 235 PKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLF---- 290
P H L A + QG + A+ RAIE P P +
Sbjct: 256 PNHAVVHGNL-------------ACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANA 302
Query: 291 ---RGTMYRRLQEFDGAVE------DFLKVLDMVTEDQ---EDMVRQAQRQLLL------ 332
+G++ ++ A+ D L L + +Q E+ VR ++ L +
Sbjct: 303 LKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAA 362
Query: 333 TYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQAL 392
+++ A +QG QE ++ +A+R Y N G+ ++ ++ A Y +A+
Sbjct: 363 AHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAI 422
Query: 393 ALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAENHFSTAIRHNPQKAQYYLYRAKSRQL 452
++P A++ + + + G +A + TA++ P Y A Q+
Sbjct: 423 QINPAFADAHSNLASIHKDSG-------NIPEAIASYRTALKLKPDFPDAYCNLAHCLQI 475
Query: 453 L 453
+
Sbjct: 476 V 476
Score = 33.5 bits (75), Expect = 0.88
Identities = 45/203 (22%), Positives = 78/203 (38%), Gaps = 32/203 (15%)
Query: 252 QQARQDAGILAVQGKLQHALQRINR-------AIENNPLDPSLFLFRGTMYRRLQEFDGA 304
+Q + G+L + + +R++R AI+ NPL + G +Y+ + A
Sbjct: 49 RQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEA 108
Query: 305 VEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQE 364
+E + L + + + + A L+ D +GA Q V L Q
Sbjct: 109 IEHYRHALRLKPDFIDGYINLA--AALVAAGDM------EGAVQAYVSAL-------QYN 153
Query: 365 KGLYINR---GDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQ 421
LY R G+ LG L A+A Y +A+ P A + +G + G +
Sbjct: 154 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG-------E 206
Query: 422 FQKAENHFSTAIRHNPQKAQYYL 444
A +HF A+ +P Y+
Sbjct: 207 IWLAIHHFEKAVTLDPNFLDAYI 229
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 51.2 bits (121), Expect = 4e-06
Identities = 82/358 (22%), Positives = 129/358 (36%), Gaps = 40/358 (11%)
Query: 512 SLQAGSPQGIVGMLKRHELERQKALALQHSWKQGEPL----IATSEELKATPEIPQVKPG 567
S Q GS G + ER + S K P I S EL TP + +
Sbjct: 163 SQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTP 222
Query: 568 SSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETE 627
+ E + K + +IPS+ S S TE
Sbjct: 223 TGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSY---------------------SPTE 261
Query: 628 MSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNR----EALSHGPRK--IKATQGQRQS 681
MS+ + Y S + S S + S SG+ + SH ++ +A R+
Sbjct: 262 MSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 682 LSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQG 741
+ SQ R+ SK K+ R + + + + RN SK R+ S S++ + +
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGR-SHNWSRNPSKERS-----HSHSRSSSKER 375
Query: 742 QRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKV-DATQGRSRGLLR 800
+ SS G Q S K R R R RS P K D ++ RS R
Sbjct: 376 DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKAR 435
Query: 801 SSTKTEAFYDS-NWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
+++ + Y + + S S++ RS A+ +S+ S + + S G SPS
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLG-SPS 492
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/302 (19%), Positives = 115/302 (38%), Gaps = 28/302 (9%)
Query: 569 SEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYL-----DQTSSASSMSFRTTGT 623
S +A + + K ++ P+K S S D++ S S R
Sbjct: 404 SRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSR 463
Query: 624 SETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLS 683
S + A RS S + D S L + S + + R S P K + + R S
Sbjct: 464 SRSPNKA---RDRSRSRSPSKERDHSQLGSPSKERDHRR---SRSPSKERQCRQSRSSSK 517
Query: 684 KTE------PTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTE 737
+ + P++ ++R S++ R+ S++ + + + R S + + + S ++
Sbjct: 518 ERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSK 577
Query: 738 ATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRG 797
+ ++ SS E + P+K PR + + A RS PSK + +SR
Sbjct: 578 ERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSK--EKAHSRSRTPSK-EGNHSQSRT 634
Query: 798 LLRSSTKTEAFY--DSNWSLSKTEYAQGQGQRSSKAEGAQGKS------QGMSSTSSKAE 849
+ S +++ +W S T + R+ + S Q +S S+A+
Sbjct: 635 SSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQAD 694
Query: 850 ST 851
+T
Sbjct: 695 AT 696
Score = 37.4 bits (85), Expect = 0.061
Identities = 52/216 (24%), Positives = 88/216 (40%), Gaps = 28/216 (12%)
Query: 669 PRKIKATQGQ--RQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRAT 726
P +K+T+ +SL T+P S RNS + ++ S+ TK S R +S +
Sbjct: 29 PASLKSTKSATPNRSLVPTKPATS--RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRS 86
Query: 727 QGQGQSSSKTEATQGQRQSSSEIEATQ----------GPRQEPSKTKTTRSPRQRPRKVK 776
+ + S T+ + +S++ Q R+ +K + S P +++
Sbjct: 87 KARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIR 146
Query: 777 AARGRSWRPSKV-------DATQGRSRGLLRSSTKTEAFYDSNWSLSKTEY----AQGQG 825
R S+V ++G+S G R+S + E +LSK Y G G
Sbjct: 147 THGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR-ERSDSQPRNLSKKSYRPPGGSGIG 205
Query: 826 QRSSKA-EGAQGKSQGMSSTSSKAESTWGPSPSLSK 860
+ S A + K Q + SK +S PSPS S+
Sbjct: 206 RSSELAVTPSTAKCQTPTGIPSKEKSD-NPSPSSSR 240
Score = 35.0 bits (79), Expect = 0.30
Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 3/148 (2%)
Query: 715 SQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRK 774
S + SSK + SS T + S AT P+K T+R+ P
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 775 VKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGA 834
K+ + S + + + RSR +RS +T + ++ SK A + +
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSR--VRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
Query: 835 QGKSQG-MSSTSSKAESTWGPSPSLSKT 861
+G++ G S SSK + +P +T
Sbjct: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRT 147
Score = 33.1 bits (74), Expect = 1.2
Identities = 42/204 (20%), Positives = 81/204 (39%), Gaps = 21/204 (10%)
Query: 573 AEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETEMSAIC 632
+ +P +E ++ + + K+ + S+ S + S + R + E
Sbjct: 524 SRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERE--- 580
Query: 633 QEYRSTSATAVTFSDSSLLKTQSSDSGNNREALS-----HGPRKIKATQGQRQSLSKTEP 687
R S ++ D S ++ + SG +R S H + + +G S S+T
Sbjct: 581 ---RRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNH-SQSRTSS 636
Query: 688 TQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQ--RQS 745
+S S+ ++ KR+ ++T ++ SQ R SKT S T + GQ Q
Sbjct: 637 KESDPSQSTVPRSPDWKRSPTRT-SSLSQNRTPSKT------SSHSPSTFPSGGQTLSQD 689
Query: 746 SSEIEATQGPRQEPSKTKTTRSPR 769
S+ +AT P + ++ S +
Sbjct: 690 DSQADATTSKATLPGERSSSSSSK 713
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/126 (26%), Positives = 66/126 (52%), Gaps = 5/126 (3%)
Query: 291 RGTMYRRLQEFDGAVEDFLKV---LDMVTEDQEDMVRQAQRQLLLTYNDFAVHCYRQGAY 347
RGT+Y + ++ A+ + K+ L+ + + ++AQ L ++ + A+ + A+
Sbjct: 276 RGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAF 335
Query: 348 QEGVLLLNKALR-DEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMG 406
+ NKAL D EKGL+ RG+ + + A AD+Q+ L L P ++ A T++
Sbjct: 336 SAAIESCNKALELDSNNEKGLF-RRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLA 394
Query: 407 LLQEKM 412
+ Q+++
Sbjct: 395 VCQQRI 400
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 51.2 bits (121), Expect = 4e-06
Identities = 57/310 (18%), Positives = 114/310 (36%), Gaps = 30/310 (9%)
Query: 550 ATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQ 609
A + +A P+I K SS + + ++ E+EK + +P K Q
Sbjct: 198 APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKK----------Q 247
Query: 610 TSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGP 669
+ + + TT T ++ S S++ +K + + + P
Sbjct: 248 VVAKAPVKAATTPTRKSSSS-------EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPP 300
Query: 670 RKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQ 729
+K TQ ++++ K +P +S +S ++ ++ + TKA S+ +
Sbjct: 301 KKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAE 360
Query: 730 GQS-SSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPR---KVKAARGRSWRP 785
S SS +++++ S T+ +P+ TT+SP +P K G+
Sbjct: 361 SSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPA--VTTKSPAVKPAAAPKQPVGGGQKLLT 418
Query: 786 SKVDATQGRSRGLLRSSTKTEAFY-------DSNWSLSKTEYAQGQGQRSSKAEGAQGKS 838
K D++ KT+ + +LS QG R S ++ S
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSS 478
Query: 839 QGMSSTSSKA 848
+ +SK+
Sbjct: 479 EEEEEKTSKS 488
Score = 48.5 bits (114), Expect = 3e-05
Identities = 63/288 (21%), Positives = 103/288 (35%), Gaps = 30/288 (10%)
Query: 569 SEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMS----FRTTGTS 624
S E+++ EEE+K K K+ P ++S D + S SS + GT+
Sbjct: 325 SSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTT 384
Query: 625 ETEMSAICQEYRSTSATAVTF---------------SDSSLLKTQSSDSGNNREALSHGP 669
+ + +S + +DSS + +SS S +
Sbjct: 385 KNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVAT 444
Query: 670 RKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQ 729
K KAT SL + Q R +SS + ++ + KT S+ K + G
Sbjct: 445 TKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKT----SKSAVKKKPQKVAGG 500
Query: 730 GQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVD 789
S A +G+ +SS+ + +E K K SPR + K A G S ++
Sbjct: 501 AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPK---ANGTSALTAQNG 557
Query: 790 ATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGK 837
S K + SL K + Q + + +AE Q K
Sbjct: 558 KAAKNSEEEEEEKKKAAVVVSKSGSLKKRK----QNEAAKEAETPQAK 601
Score = 47.8 bits (112), Expect = 5e-05
Identities = 66/314 (21%), Positives = 123/314 (39%), Gaps = 34/314 (10%)
Query: 568 SSEGEAEAPEEEEEK----EKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFR---- 619
SSE ++ +EE++K +K K + K+ P K A SDS D +S +
Sbjct: 128 SSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKI 187
Query: 620 TTGTSETEMSAICQEYRSTSATA---VTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQ 676
T T + + A + R+ A S SS + SSD +A + + + Q
Sbjct: 188 TPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQ 247
Query: 677 GQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNS---------SKTRATQ 727
++ K T +++ +SS+ ++ + K + +S K+ TQ
Sbjct: 248 VVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQ 307
Query: 728 GQGQSSSKTEATQGQRQSSSEIE-ATQGPRQEPSKTKTTRSPRQRPRKVKAARGRS---- 782
++ K + + SS E + +++ ++ P+K +++ + P KAA S
Sbjct: 308 PPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD 367
Query: 783 -------WRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQ 835
PSK T S +TK+ A + + K GQ + KA+ +
Sbjct: 368 SDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPA--AAPKQPVGGGQKLLTRKADSSS 425
Query: 836 GKSQGMSSTSSKAE 849
+ + SS K +
Sbjct: 426 SEEESSSSEEEKTK 439
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/239 (21%), Positives = 98/239 (41%), Gaps = 27/239 (11%)
Query: 565 KPGSSEGEAEAPEEEEEKEKEKKEEKKSELI-----PSKVASLSDSYLDQTSSASSMSFR 619
+ SS+ ++ + EEEEEK + +KK + + PSK AS + ++S+SS
Sbjct: 467 RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS---- 522
Query: 620 TTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQR 679
+SE E + + S A + +S L Q+ + N E +K +
Sbjct: 523 -DDSSEEEEEKL-KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKS 580
Query: 680 QSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEAT 739
SL K + ++ + + + + K + Q N+ R +G+ ++SS
Sbjct: 581 GSLKKRKQNEAAK-----------EAETPQAKKIKLQTPNTFPKR-KKGEKRASSPFRRV 628
Query: 740 QGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV-KAARGRSWRPSKVDATQGRSRG 797
R+ E+++ +K +R +V K +G+S+R K +G RG
Sbjct: 629 ---REEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHEKTKKKRGSYRG 684
Score = 36.6 bits (83), Expect = 0.10
Identities = 46/213 (21%), Positives = 81/213 (38%), Gaps = 35/213 (16%)
Query: 559 PEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSF 618
P + K +S ++E + EE+E+ + K +P+K L +S SS S
Sbjct: 73 PVAKKAKKKASSSDSE--DSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSE 130
Query: 619 RTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSG--NNREALSHGPRKIKATQ 676
++ + E K Q G +A P+K K++
Sbjct: 131 ESSDDDDEEDQ----------------------KKQPVQKGVKPQAKAAKAPPKKAKSSD 168
Query: 677 GQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKT 736
S S+ EP ++Q+ T T+ ++TKA R + K G+ SSS +
Sbjct: 169 SDSDSSSEDEPPKNQK--PKITPVTV----KAQTKAPPKPARAAPK--IANGKAASSSSS 220
Query: 737 EATQGQRQSSSEIEATQGPRQE-PSKTKTTRSP 768
++ S E +A P++ P K ++P
Sbjct: 221 SSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAP 253
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 50.4 bits (119), Expect = 7e-06
Identities = 51/290 (17%), Positives = 103/290 (35%), Gaps = 9/290 (3%)
Query: 568 SSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETE 627
S ++ + + K + KSE S S SDS +S +S S + ++ +
Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664
Query: 628 MSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEP 687
S S+ +++ + S +S + SSDS N+ E+ + ++
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES---------SDSSDSSDSDSSDS 715
Query: 688 TQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSS 747
+ S NSS + ++ +S + ++ S + S + SS + + SS
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 748 EIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEA 807
+++ S + S + S D+ S SS +++
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835
Query: 808 FYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPS 857
S+ S S S++++ + SS SS + + S S
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Score = 49.3 bits (116), Expect = 2e-05
Identities = 57/295 (19%), Positives = 114/295 (38%), Gaps = 9/295 (3%)
Query: 568 SSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETE 627
S ++++ + + + + S+ S + S+S SS SS S ++ +S+++
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 628 MSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEP 687
+ E S S+ + + SDSS + SSDS +N ++ S ++ S S
Sbjct: 624 SDSSKSE--SDSSDSDSKSDSS--DSNSSDSSDNSDS-SDSSNSSNSSDSSDSSDSSDSS 678
Query: 688 TQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSS 747
+ S NSS + + NSS++ S +SS + ++ S+S + + S S
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSES----SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734
Query: 748 EIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEA 807
+ + S + + ++ S + S SS +++
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 808 FYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTE 862
SN S S SS ++ + SS SS + ++ S S ++
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Score = 47.8 bits (112), Expect = 5e-05
Identities = 58/298 (19%), Positives = 107/298 (35%), Gaps = 6/298 (2%)
Query: 569 SEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETEM 628
S G ++ +K K + S S +S S D + S SS S ++ S++
Sbjct: 526 SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS-NSSSDSDSSD 584
Query: 629 SAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPT 688
S S S+ + SDSS SSDS ++ ++ K +++ + S +
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSS----DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640
Query: 689 QSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSE 748
S NSS + +SS + + S +SS + + SS+ ++++ S+S
Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNS-SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS 699
Query: 749 IEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAF 808
+ + + ++ S ++ S + S SS +++
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759
Query: 809 YDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTEVDQD 866
SN S S SS + + S S+ S S S S + D
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Score = 43.9 bits (102), Expect = 7e-04
Identities = 57/297 (19%), Positives = 107/297 (36%), Gaps = 15/297 (5%)
Query: 568 SSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETE 627
SS+ ++ + + + + + S S + SDS SS SS S + SE++
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNS----SDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 628 MSAICQEYRSTSATAVTFSDSSLLKTQSSDSGN--NREALSHGPRKIKATQGQRQSLSKT 685
S + S+ + + SD+S SSDS N N S ++ S S
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNS----DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 686 EPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQS 745
S NSS++ + +S + ++ S NSS + ++ S S + S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS-----DS 743
Query: 746 SSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKT 805
S +++ S + S + S D++ +S+ +
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDS 803
Query: 806 EAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTE 862
DS+ S ++ SS + + S S+ S S S S ++++
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860
Score = 43.5 bits (101), Expect = 9e-04
Identities = 52/302 (17%), Positives = 100/302 (33%), Gaps = 4/302 (1%)
Query: 569 SEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETEM 628
S +++ + + + S + SDS SS SS S ++ +S+++
Sbjct: 761 SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS 820
Query: 629 SAICQEYRST----SATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSK 684
S S+ S+ + SDSS S +NR S+ ++ S S
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Query: 685 TEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQ 744
++ NSS + + + +S + ++ S + S + + +SS +
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 745 SSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTK 804
SS +++ S + S ++ S + S SS
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 805 TEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTEVD 864
+ + S+ S S SS + + S S+ S S S S +
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 865 QD 866
D
Sbjct: 1061 SD 1062
Score = 43.1 bits (100), Expect = 0.001
Identities = 49/299 (16%), Positives = 103/299 (34%), Gaps = 1/299 (0%)
Query: 569 SEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETEM 628
S +++ + + + S + SDS SS SS S ++ +S++
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796
Query: 629 SAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPT 688
S+ + ++S ++ + S + SSDS N+ ++ + S ++ +
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 689 -QSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSS 747
+S NSS + + NSS + + +S+ + ++ S S + + SS
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 748 EIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEA 807
++ S + S + S +++ + S +++
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976
Query: 808 FYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTEVDQD 866
SN S S SS + + S S+ S S S S + D
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035
Score = 41.2 bits (95), Expect = 0.004
Identities = 52/300 (17%), Positives = 106/300 (35%), Gaps = 5/300 (1%)
Query: 568 SSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSETE 627
S ++ + + S+ S +S SDS SS SS S ++ +S++
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842
Query: 628 MSAICQEYRSTSATAVTFSDSSLL--KTQSSDSGNNREAL-SHGPRKIKATQGQRQSLSK 684
S+ + + + + SDSS + SSDS N+ ++ S + + S +
Sbjct: 843 DSSDSSD--GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900
Query: 685 TEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQ 744
++ S NSS + + + +SS++ + +S + ++ S S +
Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 745 SSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTK 804
SS + S + S + S + D++ +S+
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 805 TEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTEVD 864
+ DS+ S ++ + S S S +S ++S+ S S D
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Score = 35.0 bits (79), Expect = 0.30
Identities = 39/205 (19%), Positives = 75/205 (36%), Gaps = 17/205 (8%)
Query: 646 SDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKR 705
SDS+ S +GN K+ G+ K++ + S +SS + +
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDND---KSDSGK----GKSDSSDSDSSDSSNSSDSSDSS 567
Query: 706 NSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTT 765
+S + + S +SS + ++ SS + + SS +++ SK+ ++
Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627
Query: 766 RSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQG 825
+S S SK D++ S +S +++ SN S S
Sbjct: 628 KSESD----------SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 826 QRSSKAEGAQGKSQGMSSTSSKAES 850
SS + + S S++S S
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESS 702
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/220 (24%), Positives = 83/220 (37%), Gaps = 31/220 (14%)
Query: 544 QGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLS 603
QG L E K + E E + EE+E+++KEK+EEKK S
Sbjct: 610 QGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKK-----ESETSRE 664
Query: 604 DSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSS---DSGN 660
D Y + S ++ Q YR S ++ T SSL SS S
Sbjct: 665 DEYKQKYSRTYDETY--------------QRYRPVSTSSSTTPSSSLSTMSSSLYASSQL 710
Query: 661 NR--------EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKA 712
NR A S G K +G+++ K +SQ ++ + + KR S+
Sbjct: 711 NRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSF 770
Query: 713 -TQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEA 751
TQ N + ++ +G + +T+ R +S A
Sbjct: 771 WTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSA 810
Score = 38.9 bits (89), Expect = 0.021
Identities = 41/206 (19%), Positives = 82/206 (39%), Gaps = 9/206 (4%)
Query: 543 KQGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKE-KKEEKKSELIPSKVAS 601
++ E I S + + + K + + + ++EE+KE E +E++ +
Sbjct: 618 QEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDE 677
Query: 602 LSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNN 661
Y ++S+S+ + T + + A Q R S +T + S + ++ G
Sbjct: 678 TYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEK 737
Query: 662 REALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSS 721
RE G K Q +S+ + + +RR++ + T + + + QS S
Sbjct: 738 REEEKEGEDK-----SQPKSIRERRRPREKRRSTGVSFWT--QDSDENEQEQQSDTEEGS 790
Query: 722 KTRATQGQGQSSSKTEATQ-GQRQSS 746
+ TQ S +T +T G R S
Sbjct: 791 NKKETQTDSISRYETSSTSAGDRYDS 816
Score = 36.6 bits (83), Expect = 0.10
Identities = 63/298 (21%), Positives = 120/298 (40%), Gaps = 27/298 (9%)
Query: 490 EEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGE--P 547
EE + +L +++ V + + + I+G L+ E QK L HS K+ + P
Sbjct: 158 EEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLE----ELQKKQNLLHSEKRDKKSP 213
Query: 548 LIAT--------SEELKATPEIPQVKPGSSEGEAEAPEEE---EEKEKEKKEEKKSELIP 596
LI + S++ E ++P + E+ E+E EE+E +K E S
Sbjct: 214 LIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEEEGKKDESSCSSEED 273
Query: 597 SKVASLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSS 656
+ S S++ D+T +S++ T +++ A+ S+ T T +
Sbjct: 274 EEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATK 333
Query: 657 DSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQ 716
S E RK ++ R L KT + ++ + K + T++ S
Sbjct: 334 ISPKEEE------RKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSP 387
Query: 717 RRNSS---KTRATQGQGQSSSKTEATQGQR-QSSSEIEATQGPRQEPSKTKTTRSPRQ 770
R +SS K + +G + T +R S+S+IE + +T ++ + R+
Sbjct: 388 RLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSLRTSSSYTRRK 445
Score = 36.2 bits (82), Expect = 0.14
Identities = 52/290 (17%), Positives = 116/290 (40%), Gaps = 39/290 (13%)
Query: 555 LKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSAS 614
L +T ++ GSS ++ ++ E++K + + ++ + ++ +S +
Sbjct: 500 LSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTT 559
Query: 615 SMSFRTTGT--SETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKI 672
+++ T GT S TE+ +E R + T V R+ S RK
Sbjct: 560 TLTTTTAGTVSSTTEV----RERRRSYLTPV------------------RDEESESQRKA 597
Query: 673 KATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQS 732
++ Q ++ S T + + + KT I + S++T+ +++ + +
Sbjct: 598 RSRQARQSRRSTQGVTLTDLQEAEKT---IGRSRSTRTREQENEEKEK----------EE 644
Query: 733 SSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQ 792
K + + + + SE +Q+ S+T R RP ++ S S + ++
Sbjct: 645 KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL 704
Query: 793 GRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMS 842
S L R ++ S +S T+ + +G++ + + + KSQ S
Sbjct: 705 YASSQLNRPNSLVG--ITSAYSRGITKENEREGEKREEEKEGEDKSQPKS 752
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/220 (24%), Positives = 83/220 (37%), Gaps = 31/220 (14%)
Query: 544 QGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLS 603
QG L E K + E E + EE+E+++KEK+EEKK S
Sbjct: 697 QGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKK-----ESETSRE 751
Query: 604 DSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSS---DSGN 660
D Y + S ++ Q YR S ++ T SSL SS S
Sbjct: 752 DEYKQKYSRTYDETY--------------QRYRPVSTSSSTTPSSSLSTMSSSLYASSQL 797
Query: 661 NR--------EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKA 712
NR A S G K +G+++ K +SQ ++ + + KR S+
Sbjct: 798 NRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSF 857
Query: 713 -TQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEA 751
TQ N + ++ +G + +T+ R +S A
Sbjct: 858 WTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSA 897
Score = 38.9 bits (89), Expect = 0.021
Identities = 41/206 (19%), Positives = 82/206 (39%), Gaps = 9/206 (4%)
Query: 543 KQGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKE-KKEEKKSELIPSKVAS 601
++ E I S + + + K + + + ++EE+KE E +E++ +
Sbjct: 705 QEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDE 764
Query: 602 LSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNN 661
Y ++S+S+ + T + + A Q R S +T + S + ++ G
Sbjct: 765 TYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEK 824
Query: 662 REALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSS 721
RE G K Q +S+ + + +RR++ + T + + + QS S
Sbjct: 825 REEEKEGEDK-----SQPKSIRERRRPREKRRSTGVSFWT--QDSDENEQEQQSDTEEGS 877
Query: 722 KTRATQGQGQSSSKTEATQ-GQRQSS 746
+ TQ S +T +T G R S
Sbjct: 878 NKKETQTDSISRYETSSTSAGDRYDS 903
Score = 36.6 bits (83), Expect = 0.10
Identities = 63/298 (21%), Positives = 120/298 (40%), Gaps = 27/298 (9%)
Query: 490 EEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGE--P 547
EE + +L +++ V + + + I+G L+ E QK L HS K+ + P
Sbjct: 245 EEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLE----ELQKKQNLLHSEKRDKKSP 300
Query: 548 LIAT--------SEELKATPEIPQVKPGSSEGEAEAPEEE---EEKEKEKKEEKKSELIP 596
LI + S++ E ++P + E+ E+E EE+E +K E S
Sbjct: 301 LIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEEEGKKDESSCSSEED 360
Query: 597 SKVASLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSS 656
+ S S++ D+T +S++ T +++ A+ S+ T T +
Sbjct: 361 EEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATK 420
Query: 657 DSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQ 716
S E RK ++ R L KT + ++ + K + T++ S
Sbjct: 421 ISPKEEE------RKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSP 474
Query: 717 RRNSS---KTRATQGQGQSSSKTEATQGQR-QSSSEIEATQGPRQEPSKTKTTRSPRQ 770
R +SS K + +G + T +R S+S+IE + +T ++ + R+
Sbjct: 475 RLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSLRTSSSYTRRK 532
Score = 36.2 bits (82), Expect = 0.14
Identities = 52/290 (17%), Positives = 116/290 (40%), Gaps = 39/290 (13%)
Query: 555 LKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSAS 614
L +T ++ GSS ++ ++ E++K + + ++ + ++ +S +
Sbjct: 587 LSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTT 646
Query: 615 SMSFRTTGT--SETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKI 672
+++ T GT S TE+ +E R + T V R+ S RK
Sbjct: 647 TLTTTTAGTVSSTTEV----RERRRSYLTPV------------------RDEESESQRKA 684
Query: 673 KATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQS 732
++ Q ++ S T + + + KT I + S++T+ +++ + +
Sbjct: 685 RSRQARQSRRSTQGVTLTDLQEAEKT---IGRSRSTRTREQENEEKEK----------EE 731
Query: 733 SSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQ 792
K + + + + SE +Q+ S+T R RP ++ S S + ++
Sbjct: 732 KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL 791
Query: 793 GRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMS 842
S L R ++ S +S T+ + +G++ + + + KSQ S
Sbjct: 792 YASSQLNRPNSLVG--ITSAYSRGITKENEREGEKREEEKEGEDKSQPKS 839
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/220 (24%), Positives = 83/220 (37%), Gaps = 31/220 (14%)
Query: 544 QGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLS 603
QG L E K + E E + EE+E+++KEK+EEKK S
Sbjct: 697 QGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKK-----ESETSRE 751
Query: 604 DSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSS---DSGN 660
D Y + S ++ Q YR S ++ T SSL SS S
Sbjct: 752 DEYKQKYSRTYDETY--------------QRYRPVSTSSSTTPSSSLSTMSSSLYASSQL 797
Query: 661 NR--------EALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKA 712
NR A S G K +G+++ K +SQ ++ + + KR S+
Sbjct: 798 NRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSF 857
Query: 713 -TQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEA 751
TQ N + ++ +G + +T+ R +S A
Sbjct: 858 WTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSA 897
Score = 38.9 bits (89), Expect = 0.021
Identities = 41/206 (19%), Positives = 82/206 (39%), Gaps = 9/206 (4%)
Query: 543 KQGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKE-KKEEKKSELIPSKVAS 601
++ E I S + + + K + + + ++EE+KE E +E++ +
Sbjct: 705 QEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDE 764
Query: 602 LSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNN 661
Y ++S+S+ + T + + A Q R S +T + S + ++ G
Sbjct: 765 TYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEK 824
Query: 662 REALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSS 721
RE G K Q +S+ + + +RR++ + T + + + QS S
Sbjct: 825 REEEKEGEDK-----SQPKSIRERRRPREKRRSTGVSFWT--QDSDENEQEQQSDTEEGS 877
Query: 722 KTRATQGQGQSSSKTEATQ-GQRQSS 746
+ TQ S +T +T G R S
Sbjct: 878 NKKETQTDSISRYETSSTSAGDRYDS 903
Score = 36.6 bits (83), Expect = 0.10
Identities = 63/298 (21%), Positives = 120/298 (40%), Gaps = 27/298 (9%)
Query: 490 EEVLSTQIAHLARLQLEQMVEGSLQAGSPQGIVGMLKRHELERQKALALQHSWKQGE--P 547
EE + +L +++ V + + + I+G L+ E QK L HS K+ + P
Sbjct: 245 EEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLE----ELQKKQNLLHSEKRDKKSP 300
Query: 548 LIAT--------SEELKATPEIPQVKPGSSEGEAEAPEEE---EEKEKEKKEEKKSELIP 596
LI + S++ E ++P + E+ E+E EE+E +K E S
Sbjct: 301 LIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEEEGKKDESSCSSEED 360
Query: 597 SKVASLSDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSS 656
+ S S++ D+T +S++ T +++ A+ S+ T T +
Sbjct: 361 EEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATK 420
Query: 657 DSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQ 716
S E RK ++ R L KT + ++ + K + T++ S
Sbjct: 421 ISPKEEE------RKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSP 474
Query: 717 RRNSS---KTRATQGQGQSSSKTEATQGQR-QSSSEIEATQGPRQEPSKTKTTRSPRQ 770
R +SS K + +G + T +R S+S+IE + +T ++ + R+
Sbjct: 475 RLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSLRTSSSYTRRK 532
Score = 36.2 bits (82), Expect = 0.14
Identities = 52/290 (17%), Positives = 116/290 (40%), Gaps = 39/290 (13%)
Query: 555 LKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSAS 614
L +T ++ GSS ++ ++ E++K + + ++ + ++ +S +
Sbjct: 587 LSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTT 646
Query: 615 SMSFRTTGT--SETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKI 672
+++ T GT S TE+ +E R + T V R+ S RK
Sbjct: 647 TLTTTTAGTVSSTTEV----RERRRSYLTPV------------------RDEESESQRKA 684
Query: 673 KATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQS 732
++ Q ++ S T + + + KT I + S++T+ +++ + +
Sbjct: 685 RSRQARQSRRSTQGVTLTDLQEAEKT---IGRSRSTRTREQENEEKEK----------EE 731
Query: 733 SSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQ 792
K + + + + SE +Q+ S+T R RP ++ S S + ++
Sbjct: 732 KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL 791
Query: 793 GRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMS 842
S L R ++ S +S T+ + +G++ + + + KSQ S
Sbjct: 792 YASSQLNRPNSLVG--ITSAYSRGITKENEREGEKREEEKEGEDKSQPKS 839
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 49.3 bits (116), Expect = 2e-05
Identities = 72/356 (20%), Positives = 133/356 (37%), Gaps = 31/356 (8%)
Query: 515 AGSPQGIVGMLKRHEL-ERQKALALQH---SWKQGEPLIATSEELKATPEIPQVKPGSSE 570
+GS G V +E +R+ L H + EPL + + ++ E+ + K SE
Sbjct: 38 SGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESE-ELHRQKDSDSE 96
Query: 571 GE--AEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQ--TSSASSMSFRTTGTSET 626
E AE P + E E + SE ++ SDS ++ AS G
Sbjct: 97 SEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPA 156
Query: 627 EMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTE 686
S I + +S ++ + T LK Q SDS S P + +A+ + + K
Sbjct: 157 SDSEIEELQKSPASDSET---EDALKPQISDSE------SEEPPRHQASDSENEEPPKPR 207
Query: 687 PTQSQRRNSSKTKAT-IHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQS 745
+ S+ K + + + +A+ S+ K R + + + + +A+ + +
Sbjct: 208 MSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEE 267
Query: 746 SSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKT 805
+ + ++P + + + S + K + + S P K A+ + R K
Sbjct: 268 LPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKP 327
Query: 806 EAFYDS------------NWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAE 849
E+ DS N S + + SS +E + K Q M S + E
Sbjct: 328 ESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKE 383
Score = 30.4 bits (67), Expect = 7.5
Identities = 28/136 (20%), Positives = 61/136 (44%), Gaps = 15/136 (11%)
Query: 544 QGEPLIATSEELKATPEIPQVKPGSSEGEAEAPEEEE-EKEKEKKEEKKSELIPSKVASL 602
+GE ++ + + + K SS+ E E ++++ + ++++KE ++ ++ K A L
Sbjct: 338 KGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVL 397
Query: 603 SDSYLDQTSSASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQS------- 655
SDS D+ +++ S + +++ A+ + T + S+ K S
Sbjct: 398 SDSE-DEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEK 456
Query: 656 ------SDSGNNREAL 665
S+SGN E L
Sbjct: 457 DLFGSDSESGNEEENL 472
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 49.3 bits (116), Expect = 2e-05
Identities = 42/185 (22%), Positives = 88/185 (47%), Gaps = 11/185 (5%)
Query: 561 IPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSK----VASLSDSYLDQTSSASSM 616
+ +V+ SEGE E +E+ K K ++E + + SK + DS +++ S
Sbjct: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
Query: 617 SFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDS------GNNREALSHGPR 670
R++ + + S+ RS S + S SS +++SS G+ + S R
Sbjct: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
Query: 671 KIKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQG 730
+ + + S S + P ++++R+ S++ ++ R +T++ +RR+ S + ++
Sbjct: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRSSSS-GDRKKRRTRSRSPERRHRSSSGSSHSGS 323
Query: 731 QSSSK 735
+SSSK
Sbjct: 324 RSSSK 328
Score = 45.1 bits (105), Expect = 3e-04
Identities = 52/238 (21%), Positives = 92/238 (38%), Gaps = 45/238 (18%)
Query: 567 GSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTSET 626
G + G A +E E+KE E +EE + E LS LD+ E
Sbjct: 136 GKAVGPASILKEVEDKESEGEEEDEDE-------DLSKYKLDE--------------DED 174
Query: 627 EMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTE 686
E A +Y + S + +N++ + R + R S +
Sbjct: 175 EDDADLSKYNLDA---------------SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSS 219
Query: 687 PTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSS 746
P+ S+ R+ S+++++ ++ S++ + + R SK+R++ + SS SS
Sbjct: 220 PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS 279
Query: 747 SEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTK 804
S + K +RS RK + R RS + ++ G S RSS+K
Sbjct: 280 SP--------ERNRKRSRSRSSSSGDRKKRRTRSRS-PERRHRSSSGSSHSGSRSSSK 328
Score = 34.3 bits (77), Expect = 0.52
Identities = 28/135 (20%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Query: 727 QGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSW-RP 785
+ + + SK + + + + +++ E + +S R+ K +++ RS R
Sbjct: 158 EDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRS 217
Query: 786 SKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTS 845
S +++ RSR RSS+ S+ S S++ + R SK+ + +G SS
Sbjct: 218 SSPSSSRSRSRSRSRSSS-------SSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
Query: 846 SKAESTWGPSPSLSK 860
++ S+ SP ++
Sbjct: 271 KRSYSSSSSSPERNR 285
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 48.9 bits (115), Expect = 2e-05
Identities = 86/355 (24%), Positives = 136/355 (38%), Gaps = 39/355 (10%)
Query: 540 HSWKQGEPLIATSEELKATPEIPQVKPG--------------SSEGEAEAPEEEEEKEKE 585
HS QG PL+ T + K + +VK G S G+ + K K+
Sbjct: 950 HSGSQG-PLLTTGDLGKEKTQ-KRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKD 1007
Query: 586 KKEEKKSELIPSKVASLSDS---YLDQTSSASSMSFRTTGTSETEMSAIC--------QE 634
K ++K K S S S + TS+ S S + G S+T Q
Sbjct: 1008 KPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQI 1067
Query: 635 YRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKA--TQGQRQSLSKTEPTQSQR 692
+ T S S + S S ++ SH + T G+ +S SK+E + S +
Sbjct: 1068 PKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKS-SKSEGSSSSK 1126
Query: 693 RNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEAT 752
+SS + +S ++QS + S G SS T+ + SS +
Sbjct: 1127 LSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL 1186
Query: 753 QGPRQEPSKTKTTRSPRQRPRKVKAARG---RSWRPSKVDATQGRSRGLLRSST---KTE 806
P PS ++ + +K G S S + + G S SS+ K+
Sbjct: 1187 SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSS 1246
Query: 807 AFYDSNWSLS-KTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSK 860
+ S+ SLS KT + SS + + G S MSS+ ++ S+ G SPS +K
Sbjct: 1247 SGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSS--MSSSQNQHGSSKGKSPSRNK 1299
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 48.9 bits (115), Expect = 2e-05
Identities = 60/248 (24%), Positives = 105/248 (42%), Gaps = 19/248 (7%)
Query: 585 EKKEEKKSELIPS-------KVASLSDSYLDQTSSASSMSFRTTGTSE--TEMSAICQEY 635
E E KKS L+PS K S S SY SS+ S S T+ + E
Sbjct: 367 ECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK 426
Query: 636 RSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSKTEPTQSQR-RN 694
RS S + ++S S ++ S S +R + S+ + + S ++ + +R R
Sbjct: 427 RSYSRSP-SYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARR 485
Query: 695 SSKTKATIHKRNSSKTKATQSQRRNSSKTRAT---QGQGQSSSKTEATQGQRQSSSEIEA 751
++ + + KR +++R S++ R + SS +T SSS A
Sbjct: 486 RRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA 545
Query: 752 TQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKVDATQGRSRGLLRSSTKTEA-FYD 810
++ + S++++ R R R ++R PS ++ RSR RS +++++ Y
Sbjct: 546 SRSYSRSRSRSRSRRRSRTRTSSSSSSRS----PSPGSRSRSRSRSRSRSRSRSQSRSYS 601
Query: 811 SNWSLSKT 818
S S S T
Sbjct: 602 SADSYSST 609
Score = 39.3 bits (90), Expect = 0.016
Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 39/292 (13%)
Query: 604 DSYLDQTS--SASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNN 661
DS D +S S + S R+ G + S + R ++ + S +S + + G
Sbjct: 286 DSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM 345
Query: 662 REALSHGPRK----------IKATQGQRQSL----SKTEPTQSQRRNSS--KTKATIHKR 705
E LS R ++ + ++ SL +++ P + R+SS T+++ H
Sbjct: 346 LENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSS 405
Query: 706 NSSKTKA----TQSQRRNSSK---TRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQE 758
S +A TQS+ +S K +R+ +S ++ ++ R S + P +E
Sbjct: 406 RSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE 465
Query: 759 PSKTKTTRSPRQRPRKVKAARGRSWRPSKV---DATQGRSRGLLRSSTKTEAFY-----D 810
+ + +QR R+ R RS+ P + D+ + S+ K Y
Sbjct: 466 RDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPS 525
Query: 811 SNWSLSKT-EYAQGQGQRSSKAEGAQGKSQGMS-----STSSKAESTWGPSP 856
S+ SLS T + RS+ ++ +S+ S + +S + S+ PSP
Sbjct: 526 SSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSP 577
Score = 38.1 bits (87), Expect = 0.036
Identities = 46/214 (21%), Positives = 75/214 (35%), Gaps = 32/214 (14%)
Query: 679 RQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEA 738
R K + T+ +RR SS + K+ K+ +RR+ SK R S + +
Sbjct: 107 RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDE 166
Query: 739 TQGQRQSSSE------------IEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPS 786
+ ++QS S +Q PS ++ R K+ R S R S
Sbjct: 167 KRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCS 226
Query: 787 KV---DATQGRS----------------RGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQR 827
K D+ + +S RG++ S + S T + Q
Sbjct: 227 KTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYD 286
Query: 828 SSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKT 861
S + +Q SS S+ + PS LSK+
Sbjct: 287 SGNDTSSPPSTQ-TSSARSRGQEKGSPSGGLSKS 319
Score = 36.2 bits (82), Expect = 0.14
Identities = 54/267 (20%), Positives = 98/267 (36%), Gaps = 32/267 (11%)
Query: 622 GTSETEMSAICQEYRSTSATAVTF--------SDSSLLKTQSSDSGNNREALSHGPRKIK 673
GT+ E C+E +T + + S K + S R + S+ P +K
Sbjct: 73 GTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVK 132
Query: 674 ATQGQ-------RQSLSKTEPTQSQRRNSSKTKATIHKRNS-SKTKATQSQRRNSSKTRA 725
+ + R+S SK S S + HK+ S S+ + + R + +R+
Sbjct: 133 KKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRS 192
Query: 726 TQGQGQSSSKTEATQGQRQSSSEIEATQGPR-------QEPSKTKTTRSPRQRPRKV--K 776
+ + SS +G+ + + R ++ + +++R P Q + +
Sbjct: 193 QSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYL 252
Query: 777 AARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLS-----KTEYAQGQGQRSSKA 831
+ARG ++ L +S YDS S +T A+ +GQ
Sbjct: 253 SARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSP 312
Query: 832 EGAQGKSQGMSS--TSSKAESTWGPSP 856
G KS+ ++S TS S SP
Sbjct: 313 SGGLSKSRELNSGNTSDSGNSFTTSSP 339
Score = 33.5 bits (75), Expect = 0.88
Identities = 43/239 (17%), Positives = 89/239 (37%), Gaps = 6/239 (2%)
Query: 565 KPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTTGTS 624
+P S E EE ++ ++ ++ K + + S + + + +
Sbjct: 198 RPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGV 257
Query: 625 ETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIKATQGQRQSLSK 684
T + + T++ T S ++Q DSGN+ + ++GQ +
Sbjct: 258 ITGSGSAADLFTKTASPLTT----SRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPS 313
Query: 685 TEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSKT-RATQGQGQSSSKTEATQGQR 743
++S+ NS T + + +S + + N S T R + +G S E + ++
Sbjct: 314 GGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKK 373
Query: 744 QSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGR-SWRPSKVDATQGRSRGLLRS 801
S A P + S++ + S R ++ R S R ++ +T R RS
Sbjct: 374 SSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRS 432
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 47.4 bits (111), Expect = 6e-05
Identities = 47/219 (21%), Positives = 95/219 (43%), Gaps = 27/219 (12%)
Query: 579 EEEKEKEKKEEKKSELIPSKVASLSDSYLDQTSSASSMSFRTT-GTSETEMS-------- 629
E++K+K+ +++KK + SK S +SS+SS S T+ +SE+E +
Sbjct: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQR 291
Query: 630 -----AICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRKIK---ATQGQRQS 681
C + ++ + S L + S S +NRE PR +K + + + S
Sbjct: 292 KKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWS 351
Query: 682 LSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQ-RRNSSKTRATQGQGQSSSKTEATQ 740
S ++ ++S + + + K SS++ + + RR+ S++ + Q ++ + +
Sbjct: 352 HSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNP 411
Query: 741 GQRQSSSEIEATQGP---------RQEPSKTKTTRSPRQ 770
G+ QS + G R+ P T T + R+
Sbjct: 412 GEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
Score = 45.8 bits (107), Expect = 2e-04
Identities = 50/255 (19%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 552 SEELKATPEIPQVKPGSSEGEAEAPEEEEEKEKEKKEEKKSELIPSKVASLSDSYLDQTS 611
+ E + PE+ +K +++ + + + + EK+KK++ + + K S + +S
Sbjct: 201 ASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSS 260
Query: 612 SASSMSFRTTGTSETEMSAICQEYRSTSATAVTFSDSSLLKTQSSDSGNNREALSHGPRK 671
S+SS S+S+++ S+SS S+S N + + RK
Sbjct: 261 SSSS---------------------SSSSSSTETSESS----SESESNNKEKKIQRKKRK 295
Query: 672 IKATQGQRQSLSKTEPTQSQRRNSSKTKATIHKRNSSKTKATQSQRRNSSK-TRATQGQG 730
G S S+ + +R+ + ++ H R +K K + +S + ++ +
Sbjct: 296 KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDS 355
Query: 731 QSSSKTEATQGQRQSSSEIEATQGP--RQEPSKTKTTRSP---RQRPRKVKAARGRSWRP 785
S+T +++ S E + R+E S+ +RSP +QR + +A R
Sbjct: 356 DKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQ 415
Query: 786 SKVDATQGRSRGLLR 800
S+ + ++ L R
Sbjct: 416 SRRNDSRSHGTDLYR 430
Score = 30.8 bits (68), Expect = 5.7
Identities = 33/160 (20%), Positives = 66/160 (41%), Gaps = 19/160 (11%)
Query: 705 RNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKT 764
R K K +++ K+R+ + +SSS + ++ SSS E ++ + S K
Sbjct: 230 RLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSS---SSSSSTETSESSSESESNNKE 286
Query: 765 TRSPRQRPRKVKAARGRSWRPSKVDATQGR-------SRGLLRSSTKTEAFY-------- 809
+ R++ +K K + + + D ++ R S R K + +
Sbjct: 287 KKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRE 346
Query: 810 DSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAE 849
DS WS S ++ + S + G++ K +G S + + E
Sbjct: 347 DSKWSHSDSDKKSRTHKHSPEKRGSERK-EGSSRSHGREE 385
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.127 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,640,945
Number of Sequences: 37866
Number of extensions: 1433805
Number of successful extensions: 21104
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 292
Number of HSP's successfully gapped in prelim test: 691
Number of HSP's that attempted gapping in prelim test: 13580
Number of HSP's gapped (non-prelim): 4749
length of query: 873
length of database: 18,247,518
effective HSP length: 111
effective length of query: 762
effective length of database: 14,044,392
effective search space: 10701826704
effective search space used: 10701826704
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.