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Search of human proteins with 214010191
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|214010191 ribonuclease H2, subunit B isoform 2 [Homo
sapiens]
(257 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|214010191 ribonuclease H2, subunit B isoform 2 [Homo sapiens] 522 e-148
gi|186910286 ribonuclease H2, subunit B isoform 1 [Homo sapiens] 503 e-143
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 31 1.2
gi|169205589 PREDICTED: chromosome 12 open reading frame 55 [Hom... 30 2.1
gi|169203876 PREDICTED: hypothetical protein [Homo sapiens] 30 2.1
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 30 2.1
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 30 2.1
gi|151301150 sel-1 suppressor of lin-12-like 2 [Homo sapiens] 30 2.7
gi|170784817 transcription factor CP2-like 3 [Homo sapiens] 29 3.5
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 29 4.6
gi|38049009 sister-of-mammalian grainyhead protein isoform 2 [Ho... 29 4.6
gi|42789723 sister-of-mammalian grainyhead protein isoform 3 [Ho... 29 4.6
gi|38049007 sister-of-mammalian grainyhead protein isoform 1 [Ho... 29 4.6
gi|4757956 cadherin 16 precursor [Homo sapiens] 29 4.6
gi|7706607 LEM domain containing 3 [Homo sapiens] 29 4.6
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 28 6.0
gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform... 28 7.9
gi|148596992 heart alpha-kinase [Homo sapiens] 28 7.9
gi|160420328 iron-sulfur cluster assembly 2 [Homo sapiens] 28 7.9
>gi|214010191 ribonuclease H2, subunit B isoform 2 [Homo sapiens]
Length = 257
Score = 522 bits (1345), Expect = e-148
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 1 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 60
MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
Sbjct: 1 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 60
Query: 61 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 120
FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
Sbjct: 61 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 120
Query: 121 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 180
VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
Sbjct: 121 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 180
Query: 181 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 240
NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
Sbjct: 181 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 240
Query: 241 LPNPPSKMAAQRQKRGK 257
LPNPPSKMAAQRQKRGK
Sbjct: 241 LPNPPSKMAAQRQKRGK 257
>gi|186910286 ribonuclease H2, subunit B isoform 1 [Homo sapiens]
Length = 312
Score = 503 bits (1296), Expect = e-143
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 60
MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
Sbjct: 1 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 60
Query: 61 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 120
FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
Sbjct: 61 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 120
Query: 121 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 180
VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
Sbjct: 121 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 180
Query: 181 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 240
NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
Sbjct: 181 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 240
Query: 241 LPNPPSK 247
LPNPPSK
Sbjct: 241 LPNPPSK 247
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
Query: 168 EKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDD 227
E+K +T+ ALK VN++ V+ + S DQ S + D +R+ + + KE
Sbjct: 113 EQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIR--DLLRF-----KEEVTKERDQL 165
Query: 228 LSKYLKLPEPSA 239
LS+ +KL E A
Sbjct: 166 LSEVVKLRESLA 177
>gi|169205589 PREDICTED: chromosome 12 open reading frame 55 [Homo
sapiens]
Length = 1241
Score = 30.0 bits (66), Expect = 2.1
Identities = 16/67 (23%), Positives = 35/67 (52%)
Query: 132 PGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQS 191
PG + L E++ PE D+ K +K+ L +K+N+ +A L+T+ + ++ + +
Sbjct: 1075 PGCKSLFDGSNEQEEMPEEDSSKKSLKTKKPQQILLPEKINEQLALLETHLLKLTKQYVT 1134
Query: 192 TAFFSGD 198
+ G+
Sbjct: 1135 SELSGGE 1141
>gi|169203876 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1241
Score = 30.0 bits (66), Expect = 2.1
Identities = 16/67 (23%), Positives = 35/67 (52%)
Query: 132 PGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQS 191
PG + L E++ PE D+ K +K+ L +K+N+ +A L+T+ + ++ + +
Sbjct: 1075 PGCKSLFDGSNEQEEMPEEDSSKKSLKTKKPQQILLPEKINEQLALLETHLLKLTKQYVT 1134
Query: 192 TAFFSGD 198
+ G+
Sbjct: 1135 SELSGGE 1141
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 30.0 bits (66), Expect = 2.1
Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 167 LEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSD 226
L KKV+ T+ + K+ N + + + S E + H + + P E++D
Sbjct: 259 LNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKV-EAPPSEVAD 317
Query: 227 DL-----SKYLKLPEPSASLPNPPSKMAAQRQKR 255
L SK ++LPEP + P KM + + +
Sbjct: 318 TLVIMTASKGVRLPEPKDKILETPQKMTEKSESK 351
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 30.0 bits (66), Expect = 2.1
Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 167 LEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSD 226
L KKV+ T+ + K+ N + + + S E + H + + P E++D
Sbjct: 259 LNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKV-EAPPSEVAD 317
Query: 227 DL-----SKYLKLPEPSASLPNPPSKMAAQRQKR 255
L SK ++LPEP + P KM + + +
Sbjct: 318 TLVIMTASKGVRLPEPKDKILETPQKMTEKSESK 351
>gi|151301150 sel-1 suppressor of lin-12-like 2 [Homo sapiens]
Length = 688
Score = 29.6 bits (65), Expect = 2.7
Identities = 31/142 (21%), Positives = 55/142 (38%), Gaps = 31/142 (21%)
Query: 93 PLFLLLHYLI---------KADKEGKFQPLDQVVVDNVFPNCILLLKLPGLEKLLHHVTE 143
PL LL+ LI KA++ K Q V + + +++ L H+ E
Sbjct: 3 PLSLLIEILIILGVTIKTIKAEEHNKRQKERNVTTQ---------VSVNEIKQYLSHILE 53
Query: 144 EKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQ---- 199
++ + + NK+ K+K + + K Q LK N ++ + + GDQ
Sbjct: 54 QRTSSNVINKRENLLEKKKNQRKIRIKGIQNKDILKRNKNHLQKQAEKNFTDEGDQLFKM 113
Query: 200 ---------ASTDKEEDYIRYA 212
+ KEE Y+ +A
Sbjct: 114 GIKVLQQSKSQKQKEEAYLLFA 135
>gi|170784817 transcription factor CP2-like 3 [Homo sapiens]
Length = 625
Score = 29.3 bits (64), Expect = 3.5
Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 119 DNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAAL 178
D+VF L+LK P ++ L+ ++E+ G P K YK SK+ L ++ + + +
Sbjct: 547 DDVFD--ALMLKSPTVKGLMEAISEKYGLPVEKIAKLYKKSKKGILVNMDDNIIEHYSNE 604
Query: 179 KTNNVNVSSRVQ 190
T +N+ S V+
Sbjct: 605 DTFILNMESMVE 616
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 28.9 bits (63), Expect = 4.6
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 123 PNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNN 182
P + LL++P L K K + + +K + SKE +K E K N T AL++ N
Sbjct: 1677 PVMLTLLRVPRLNK------NSKNSNGQELEKTLEESKEMDIKRKENKGNDTPLALESTN 1730
Query: 183 VNVSSRVQST 192
+ ++ T
Sbjct: 1731 TEKETSLEET 1740
>gi|38049009 sister-of-mammalian grainyhead protein isoform 2 [Homo
sapiens]
Length = 602
Score = 28.9 bits (63), Expect = 4.6
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 103 KADKEGKFQPLDQVV---VDNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYS 159
K KEG Q + V + VF L+LK P L+ L + ++E+ G PE + K YK
Sbjct: 505 KQAKEGDLQRVLLYVRRETEEVFD--ALMLKTPDLKGLRNAISEKYGFPEENIYKVYKKC 562
Query: 160 KEKTLKWLEKKVNQ 173
K L ++ + Q
Sbjct: 563 KRGILVNMDNNIIQ 576
>gi|42789723 sister-of-mammalian grainyhead protein isoform 3 [Homo
sapiens]
Length = 509
Score = 28.9 bits (63), Expect = 4.6
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 103 KADKEGKFQPLDQVV---VDNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYS 159
K KEG Q + V + VF L+LK P L+ L + ++E+ G PE + K YK
Sbjct: 412 KQAKEGDLQRVLLYVRRETEEVFD--ALMLKTPDLKGLRNAISEKYGFPEENIYKVYKKC 469
Query: 160 KEKTLKWLEKKVNQ 173
K L ++ + Q
Sbjct: 470 KRGILVNMDNNIIQ 483
>gi|38049007 sister-of-mammalian grainyhead protein isoform 1 [Homo
sapiens]
Length = 607
Score = 28.9 bits (63), Expect = 4.6
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 103 KADKEGKFQPLDQVV---VDNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYS 159
K KEG Q + V + VF L+LK P L+ L + ++E+ G PE + K YK
Sbjct: 510 KQAKEGDLQRVLLYVRRETEEVFD--ALMLKTPDLKGLRNAISEKYGFPEENIYKVYKKC 567
Query: 160 KEKTLKWLEKKVNQ 173
K L ++ + Q
Sbjct: 568 KRGILVNMDNNIIQ 581
>gi|4757956 cadherin 16 precursor [Homo sapiens]
Length = 829
Score = 28.9 bits (63), Expect = 4.6
Identities = 17/70 (24%), Positives = 30/70 (42%)
Query: 39 KLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLL 98
KLV P G GA + ++++ ++ + + S +G L P DP+ L
Sbjct: 537 KLVGPGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTL 596
Query: 99 HYLIKADKEG 108
+ + D EG
Sbjct: 597 RFSLVNDSEG 606
>gi|7706607 LEM domain containing 3 [Homo sapiens]
Length = 911
Score = 28.9 bits (63), Expect = 4.6
Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 5/64 (7%)
Query: 11 VGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKH 70
+G + H+ + L+ S +G++ + V+ S EG +Y+ CL + K FK H
Sbjct: 798 IGDQWHLAIQEAILEKCSDN--DGIVHIA-VDKNSREGCVYV--KCLSPEYAGKAFKALH 852
Query: 71 HSWF 74
SWF
Sbjct: 853 GSWF 856
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 28.5 bits (62), Expect = 6.0
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 25/132 (18%)
Query: 129 LKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALK-----TNNV 183
LKL GLE+L+ + + KG ++ N + K + L+ E K+N+ + K NN+
Sbjct: 1323 LKLKGLEELISTLKDTKGAQKVIN----WHMKIEELRLQELKLNRELVKDKEEIKYLNNI 1378
Query: 184 ------NVSSR----VQSTAFFSGDQASTDKEE-DYIRYAHGLISDYIPKELSDDLSKYL 232
+SS VQ F Q + D+ E D R D ++ ++ L+
Sbjct: 1379 ISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQL-----DIFDRQQNEILNAAQ 1433
Query: 233 KLPEPSASLPNP 244
K E + S+P+P
Sbjct: 1434 KFEEATGSIPDP 1445
>gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform b
[Homo sapiens]
Length = 807
Score = 28.1 bits (61), Expect = 7.9
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
Query: 138 LHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT-----NNVNVSSRVQST 192
L + E+K I K+ K KEK K + + + VA+LK N+ +VS S+
Sbjct: 196 LDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQMEYERQVASLKAANAAENDFSVSQAEMSS 255
Query: 193 AFFSGDQASTDKEEDYIRYAHG 214
+ AS K E + AHG
Sbjct: 256 RQAMLENASDIKLEKFSISAHG 277
>gi|148596992 heart alpha-kinase [Homo sapiens]
Length = 2170
Score = 28.1 bits (61), Expect = 7.9
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 119 DNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAAL 178
+N+ N L K+P LE L H TEEK +P+ + K +E L KK+ +
Sbjct: 1746 ENIRKNSAFLKKMPKLETSLSH-TEEKQDPKKPSCK-----REGRAPVLLKKIQAEMFPE 1799
Query: 179 KTNNVNVS 186
+ NV +S
Sbjct: 1800 HSGNVKLS 1807
>gi|160420328 iron-sulfur cluster assembly 2 [Homo sapiens]
Length = 154
Score = 28.1 bits (61), Expect = 7.9
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 5/46 (10%)
Query: 42 NPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHF 87
+P +GEG I L + C+Q+L E+ E F+ V+ GG F
Sbjct: 42 SPEAGEGQIRLTDSCVQRLLEITEGSE-----FLRLQVEGGGCSGF 82
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,089,987
Number of Sequences: 37866
Number of extensions: 449692
Number of successful extensions: 1453
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1443
Number of HSP's gapped (non-prelim): 19
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.