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Search of human proteins with 21361975
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361975 voltage-dependent calcium channel gamma-7 subunit
[Homo sapiens]
(275 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 559 e-159
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 415 e-116
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso... 283 1e-76
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho... 115 3e-26
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 113 2e-25
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho... 109 3e-24
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 105 4e-23
gi|22748835 transmembrane protein 178 [Homo sapiens] 46 4e-05
gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Ho... 42 4e-04
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 41 0.001
gi|10863887 claudin 1 [Homo sapiens] 41 0.001
gi|226437592 transmembrane protein 114 [Homo sapiens] 41 0.001
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 39 0.004
gi|157951718 GSG1-like isoform 1 [Homo sapiens] 39 0.004
gi|21389571 GSG1-like isoform 2 [Homo sapiens] 39 0.005
gi|183979973 claudin 19 isoform a [Homo sapiens] 37 0.014
gi|183979975 claudin 19 isoform b [Homo sapiens] 37 0.014
gi|5921465 claudin 10 isoform b [Homo sapiens] 37 0.019
gi|188528658 transmembrane protein 182 [Homo sapiens] 36 0.032
gi|169211272 PREDICTED: germ cell-specific gene 1-like protein 2... 35 0.093
gi|169211660 PREDICTED: germ cell-specific gene 1-like protein 2... 35 0.093
gi|169210878 PREDICTED: germ cell-specific gene 1-like protein 2... 35 0.093
gi|225703142 claudin 14 [Homo sapiens] 34 0.16
gi|21536294 claudin 14 [Homo sapiens] 34 0.16
gi|153792186 claudin 7 [Homo sapiens] 34 0.16
gi|225703138 claudin 14 [Homo sapiens] 34 0.16
gi|6912314 claudin 14 [Homo sapiens] 34 0.16
gi|225703140 claudin 14 [Homo sapiens] 34 0.16
gi|62000698 transmembrane protein 225 [Homo sapiens] 33 0.27
gi|22027554 voltage-dependent calcium channel gamma-6 subunit is... 33 0.35
>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
sapiens]
Length = 275
Score = 559 bits (1440), Expect = e-159
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR
Sbjct: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
Query: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI
Sbjct: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
Query: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA
Sbjct: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
Query: 181 FAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRG 240
FAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRG
Sbjct: 181 FAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRG 240
Query: 241 RSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC 275
RSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC
Sbjct: 241 RSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC 275
>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
Length = 275
Score = 415 bits (1066), Expect = e-116
Identities = 194/275 (70%), Positives = 229/275 (83%)
Query: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
MS C +ALTLLSSVF CGL L+GIAVSTDYWLY+EEG ++PQNQ+TE+KM+LH+GLWR
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
Query: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
VCF AG E+GRC EY + L +E+T N+LK +R+ATPFP+VSLF +F F+++NI
Sbjct: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
Query: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
GHIRP RTILAFVSGIFFILSGLSLVVGLVLYISSINDE++NR +E YF+Y+YGWSFA
Sbjct: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
Query: 181 FAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRG 240
FAA SFLL E AGVMSVYLF KRY E+MYRPHP FYRPRLS+CSDYSGQFL P+AW RG
Sbjct: 181 FAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRG 240
Query: 241 RSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC 275
RSPSDISS+ S+QM NYP +K PD+ +S+SPC
Sbjct: 241 RSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC 275
>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
isoform b [Homo sapiens]
Length = 296
Score = 283 bits (723), Expect = 1e-76
Identities = 133/190 (70%), Positives = 159/190 (83%)
Query: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
MS C +ALTLLSSVF CGL L+GIAVSTDYWLY+EEG ++PQNQ+TE+KM+LH+GLWR
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
Query: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
VCF AG E+GRC EY + L +E+T N+LK +R+ATPFP+VSLF +F F+++NI
Sbjct: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
Query: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
GHIRP RTILAFVSGIFFILSGLSLVVGLVLYISSINDE++NR +E YF+Y+YGWSFA
Sbjct: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
Query: 181 FAASSFLLKE 190
FAA SFLL E
Sbjct: 181 FAAISFLLTE 190
>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
sapiens]
Length = 327
Score = 115 bits (289), Expect = 3e-26
Identities = 67/214 (31%), Positives = 111/214 (51%), Gaps = 10/214 (4%)
Query: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYME----EGTVLPQNQTTEVKMA--- 53
M C LL++ L+ IA+ TDYWLY GT L + + A
Sbjct: 1 MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
Query: 54 -LHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVF 112
H+GLWRVC G KG C +F E + +++E +L+ VR ++ FP++S L+
Sbjct: 61 LTHSGLWRVCCIEGIYKGHCFRINHFPEDN-DYDHDSSEYLLRIVRASSVFPILSTILLL 119
Query: 113 TAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFH 172
+ G I ++ + +GI F+ +GLS ++G+++YISS + ++ ++ H
Sbjct: 120 LGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKN-H 178
Query: 173 YRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAE 206
Y YGWSF F A SF++ E GV++V ++ ++ E
Sbjct: 179 YNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKE 212
>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
sapiens]
Length = 323
Score = 113 bits (283), Expect = 2e-25
Identities = 67/202 (33%), Positives = 113/202 (55%), Gaps = 11/202 (5%)
Query: 11 LLSSVFGACGLLLVGIAVSTDYWLYME---EGTVLPQNQTTEV--KMALHAGLWRVCFFA 65
LL++V L+ IAV TDYWLY + + +N+T++ ++ H+GLWR C
Sbjct: 11 LLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLE 70
Query: 66 GREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRP 125
G KG C ++F E + + + E L+ VR ++ FP++S+ L+F +
Sbjct: 71 GNFKGLCKQIDHFPE-DADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYK 129
Query: 126 QRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFH-YRYGWSFAFAAS 184
R + +GIFF+ +GLS ++G+++YIS+ + PS S+ + Y YGWSF F A
Sbjct: 130 TRHNIILSAGIFFVSAGLSNIIGIIVYISANAGD----PSKSDSKKNSYSYGWSFYFGAL 185
Query: 185 SFLLKEGAGVMSVYLFTKRYAE 206
SF++ E GV++V++F R+ +
Sbjct: 186 SFIIAEMVGVLAVHMFIDRHKQ 207
>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
sapiens]
Length = 315
Score = 109 bits (272), Expect = 3e-24
Identities = 63/211 (29%), Positives = 109/211 (51%), Gaps = 10/211 (4%)
Query: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYME-----EGTVLPQNQTTEVKMALH 55
M C L+++V L+ IAV TDYWLY + T + ++ H
Sbjct: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH 60
Query: 56 AGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAF 115
+GLWR C G +G C ++F E + + + E +L+ VR ++ FP++S+ L+F
Sbjct: 61 SGLWRTCCLEGAFRGVCKKIDHFPE-DADYEQDTAEYLLRAVRASSVFPILSVTLLFFGG 119
Query: 116 VISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRY 175
+ R + +GIFF+ +GLS ++G+++YIS+ + R S Y Y
Sbjct: 120 LCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKS----YSY 175
Query: 176 GWSFAFAASSFLLKEGAGVMSVYLFTKRYAE 206
GWSF F A SF++ E GV++V+++ +++ +
Sbjct: 176 GWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQ 206
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 105 bits (262), Expect = 4e-23
Identities = 67/221 (30%), Positives = 108/221 (48%), Gaps = 20/221 (9%)
Query: 4 CSSRALTLLSSVFGACGLLLVGIAVSTDYWLYM--------------EEGTVLPQNQTTE 49
C LL++V L+ IA+STDYWLY ++GT
Sbjct: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
Query: 50 VKM----ALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPM 105
K H+GLWR+C G ++G CV +F E + + ++ E +L+ VR ++ FP+
Sbjct: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPE-DTDYDHDSAEYLLRVVRASSIFPI 133
Query: 106 VSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPS 165
+S L+ V + + + +GI F+ +GLS ++G+++YIS+ N
Sbjct: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192
Query: 166 SSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAE 206
E+ HY YGWSF F SF+L E GV++V ++ +R E
Sbjct: 193 DEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSRE 233
>gi|22748835 transmembrane protein 178 [Homo sapiens]
Length = 297
Score = 45.8 bits (107), Expect = 4e-05
Identities = 37/177 (20%), Positives = 77/177 (43%), Gaps = 28/177 (15%)
Query: 53 ALHAGLWRVCFFAGREKG-----------RCVASEYFLEPEINL----------VTENTE 91
A ++GLWR C+F G ++ RC A +Y I L + ++
Sbjct: 109 ATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEW 168
Query: 92 NILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVL 151
++L R F +++ ++ +++ + + ++ V+G+ F+++G+ + L
Sbjct: 169 HLLHLRRITAGFLGMAVAVLLCGCIVATVSFFW-EESLTQHVAGLLFLMTGIFCTISLCT 227
Query: 152 YISSINDEVMNRPS---SSEQYFHYRYGWSF--AFAASSFLLKEGAGVMSVYLFTKR 203
Y +SI+ ++ P S + Y WS A+ + F++ G G+ Y F R
Sbjct: 228 YAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAG-GLCIAYPFISR 283
>gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Homo
sapiens]
Length = 222
Score = 42.4 bits (98), Expect = 4e-04
Identities = 44/184 (23%), Positives = 76/184 (41%), Gaps = 26/184 (14%)
Query: 20 GLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVC--------------FFA 65
G++L AV TD+W + + N T E A H GLWR+C
Sbjct: 19 GIVLAMTAVVTDHWAVLSPH-MEHHNTTCE---AAHFGLWRICTKRIPMDDSKTCGPITL 74
Query: 66 GREKGRCVASEYFLEPEINLVTE-NTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIR 124
EK C +F E + + E T+ A + ++ + V+ ++G
Sbjct: 75 PGEKN-CSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGK-- 131
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
+R L + +F+ +GL ++V + + S+ + S + Y Y WSFA A +
Sbjct: 132 -KRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMI---DSEDTVWIEYYYSWSFACACA 187
Query: 185 SFLL 188
+F+L
Sbjct: 188 AFIL 191
>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 40.8 bits (94), Expect = 0.001
Identities = 39/191 (20%), Positives = 77/191 (40%), Gaps = 21/191 (10%)
Query: 13 SSVFGACGLLLVGIAVSTDYWLYME-----------EGTVLPQNQTTEVKMALHAGLWRV 61
+++ GA +L+ A+ TD+W ++ + + N++ ++ H+GLWR
Sbjct: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRT 71
Query: 62 CFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG 121
C R + C E V+E++ +L T +SL L+ + +
Sbjct: 72 C----RVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127
Query: 122 HIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQ-----YFHYRYG 176
+ Q +L ++GI F+ + + G+ +YI+ E+ +G
Sbjct: 128 FLL-QAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186
Query: 177 WSFAFAASSFL 187
WS A SF+
Sbjct: 187 WSLALGWISFI 197
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 40.8 bits (94), Expect = 0.001
Identities = 39/188 (20%), Positives = 71/188 (37%), Gaps = 27/188 (14%)
Query: 20 GLLLVGIAVSTDYWLYMEEGTVLPQ-------NQTTEVKMALHAGLWRVCFFAGREKGRC 72
GL L+G ++ W+ T LPQ A++ GLW C + +C
Sbjct: 5 GLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQC 64
Query: 73 VASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG--------HIR 124
+ L N+ T++ +V + L A ++ +G
Sbjct: 65 KVFDSLL------------NLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDE 112
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
Q+ +A + G F+L+GL+++V Y + I E + + + + +AA+
Sbjct: 113 VQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAA 172
Query: 185 SFLLKEGA 192
S L GA
Sbjct: 173 SLCLLGGA 180
>gi|226437592 transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 40.8 bits (94), Expect = 0.001
Identities = 39/191 (20%), Positives = 77/191 (40%), Gaps = 21/191 (10%)
Query: 13 SSVFGACGLLLVGIAVSTDYWLYME-----------EGTVLPQNQTTEVKMALHAGLWRV 61
+++ GA +L+ A+ TD+W ++ + + N++ ++ H+GLWR
Sbjct: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRT 71
Query: 62 CFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG 121
C R + C E V+E++ +L T +SL L+ + +
Sbjct: 72 C----RVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127
Query: 122 HIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQ-----YFHYRYG 176
+ Q +L ++GI F+ + + G+ +YI+ E+ +G
Sbjct: 128 FLL-QAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186
Query: 177 WSFAFAASSFL 187
WS A SF+
Sbjct: 187 WSLALGWISFI 197
>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
sapiens]
Length = 217
Score = 39.3 bits (90), Expect = 0.004
Identities = 38/191 (19%), Positives = 77/191 (40%), Gaps = 21/191 (10%)
Query: 13 SSVFGACGLLLVGIAVSTDYWLYME-----------EGTVLPQNQTTEVKMALHAGLWRV 61
+++ GA +L+ A+ T++W ++ + + N++ ++ H+GLWR
Sbjct: 6 AALTGALSFVLLAAAIGTEFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRT 65
Query: 62 CFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG 121
C R + C E V+E++ +L T +SL L+ + +
Sbjct: 66 C----RVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 121
Query: 122 HIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQ-----YFHYRYG 176
+ Q +L ++GI F+ + + G+ +YI+ E+ +G
Sbjct: 122 FLL-QAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 180
Query: 177 WSFAFAASSFL 187
WS A SF+
Sbjct: 181 WSLALGWISFI 191
>gi|157951718 GSG1-like isoform 1 [Homo sapiens]
Length = 331
Score = 39.3 bits (90), Expect = 0.004
Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 20/176 (11%)
Query: 55 HAGLWRVCFFAGREKGRCVASEYFLEPEIN---LVTENTENILKTVRTATPFPMVSLFLV 111
H G+W C G S L P L +L + F ++ L L
Sbjct: 102 HTGIWYSCEEELSGLGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELF 161
Query: 112 FTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYF 171
++ VI + L + +F +LSGL +V ++Y V P +
Sbjct: 162 HSSNVIDGLK--------LNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPH- 212
Query: 172 HYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAE--------EEMYRPHPAFYRP 219
+ YGWSF A SF A V ++ +TK E E+ YR P F P
Sbjct: 213 SWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDP 268
>gi|21389571 GSG1-like isoform 2 [Homo sapiens]
Length = 176
Score = 38.9 bits (89), Expect = 0.005
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 134 SGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAG 193
+ +F +LSGL +V ++Y V P + + YGWSF A SF A
Sbjct: 21 AAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPH-SWDYGWSFCLAWGSFTCCMAAS 79
Query: 194 VMSVYLFTKRYAE--------EEMYRPHPAFYRP 219
V ++ +TK E E+ YR P F P
Sbjct: 80 VTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDP 113
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 37.4 bits (85), Expect = 0.014
Identities = 42/212 (19%), Positives = 84/212 (39%), Gaps = 28/212 (13%)
Query: 20 GLLLVGIAVSTDYWLYMEEGTVLPQNQTTE-------VKMALHAGLWRVCFFAGREKGRC 72
GL L+G ++ W+ + T LPQ + + + L+ GLW C + +C
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 73 VASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG----HIRPQRT 128
+ L + + +++A +V++ L F A V+S +G +
Sbjct: 65 KLYDSLLALDGH------------IQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNP 112
Query: 129 I----LAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
I +A G FIL+GL + + Y + + E N + + + +A++
Sbjct: 113 IAKGRVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASA 172
Query: 185 SFLLKEGAGVMSVYLFTKR-YAEEEMYRPHPA 215
+ G+ + +R + + YRP P+
Sbjct: 173 GLAVLGGSFLCCTCPEPERPNSSPQPYRPGPS 204
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 37.4 bits (85), Expect = 0.014
Identities = 42/212 (19%), Positives = 84/212 (39%), Gaps = 28/212 (13%)
Query: 20 GLLLVGIAVSTDYWLYMEEGTVLPQNQTTE-------VKMALHAGLWRVCFFAGREKGRC 72
GL L+G ++ W+ + T LPQ + + + L+ GLW C + +C
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 73 VASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG----HIRPQRT 128
+ L + + +++A +V++ L F A V+S +G +
Sbjct: 65 KLYDSLLALDGH------------IQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNP 112
Query: 129 I----LAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
I +A G FIL+GL + + Y + + E N + + + +A++
Sbjct: 113 IAKGRVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASA 172
Query: 185 SFLLKEGAGVMSVYLFTKR-YAEEEMYRPHPA 215
+ G+ + +R + + YRP P+
Sbjct: 173 GLAVLGGSFLCCTCPEPERPNSSPQPYRPGPS 204
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 37.0 bits (84), Expect = 0.019
Identities = 43/188 (22%), Positives = 74/188 (39%), Gaps = 14/188 (7%)
Query: 5 SSRALTLLSSVFGACGLLLVGIAVSTDYWLYME-EGTVLPQNQTTEVKMALHAGLWRVCF 63
+S A +++ + G +LV + TDYW +GTV+ A LW+ C
Sbjct: 2 ASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVI-------TTATYWANLWKACV 54
Query: 64 FAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHI 123
C L ++ + ++ + F S+F +F + +G
Sbjct: 55 TDSTGVSNCKDFPSMLA--LDGYIQACRGLMIAAVSLGFFG--SIFALF-GMKCTKVGGS 109
Query: 124 RPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAA 183
+ +A ++GI FILSGL + G LY + I E + P EQ + +A
Sbjct: 110 DKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD-PLFVEQKYELGAALFIGWAG 168
Query: 184 SSFLLKEG 191
+S + G
Sbjct: 169 ASLCIIGG 176
>gi|188528658 transmembrane protein 182 [Homo sapiens]
Length = 229
Score = 36.2 bits (82), Expect = 0.032
Identities = 50/220 (22%), Positives = 86/220 (39%), Gaps = 35/220 (15%)
Query: 14 SVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCV 73
++FGA G+LL +A +DYWL E + E H G + C+F G
Sbjct: 11 ALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNG------- 63
Query: 74 ASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFV 133
+V EN NI K T P P + T +S +R + ++
Sbjct: 64 -----------IVEENDSNIWKFWYTNQP-PSKNC----THAYLSPYPFMRGEHNSTSYD 107
Query: 134 SGIFFI-LSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGA 192
S + + + +++G+V + + + P +S +F Y+ G AA
Sbjct: 108 SAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFAS--HFLYKAGGGSYIAAGILF---SL 162
Query: 193 GVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFL 232
VM ++ + A+ E YR ++ DC D++ L
Sbjct: 163 VVMLYVIWVQAVADMESYR------NMKMKDCLDFTPSVL 196
>gi|169211272 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 34.7 bits (78), Expect = 0.093
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 12/112 (10%)
Query: 136 IFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVM 195
IF +L+GL +V ++Y + V P + + YGWS+ A SF L V
Sbjct: 165 IFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKPQT-WDYGWSYCLAWGSFALCLAVSVS 223
Query: 196 SVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEA----WRRGRSP 243
++ FT A E A R S S FL+PEA W+ G +P
Sbjct: 224 AMSRFTA--ARLEFTEKQQAQNGSRHSQHS-----FLEPEASESIWKTGAAP 268
>gi|169211660 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 34.7 bits (78), Expect = 0.093
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 12/112 (10%)
Query: 136 IFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVM 195
IF +L+GL +V ++Y + V P + + YGWS+ A SF L V
Sbjct: 165 IFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKPQT-WDYGWSYCLAWGSFALCLAVSVS 223
Query: 196 SVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEA----WRRGRSP 243
++ FT A E A R S S FL+PEA W+ G +P
Sbjct: 224 AMSRFTA--ARLEFTEKQQAQNGSRHSQHS-----FLEPEASESIWKTGAAP 268
>gi|169210878 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 34.7 bits (78), Expect = 0.093
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 12/112 (10%)
Query: 136 IFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVM 195
IF +L+GL +V ++Y + V P + + YGWS+ A SF L V
Sbjct: 165 IFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKPQT-WDYGWSYCLAWGSFALCLAVSVS 223
Query: 196 SVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEA----WRRGRSP 243
++ FT A E A R S S FL+PEA W+ G +P
Sbjct: 224 AMSRFTA--ARLEFTEKQQAQNGSRHSQHS-----FLEPEASESIWKTGAAP 268
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 33.9 bits (76), Expect = 0.16
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 9/135 (6%)
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
P +T A + G FIL+GL +V + + + N S F F +S
Sbjct: 112 PAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISS 171
Query: 185 SFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQ-PEAWRRGRSP 243
S L G L +E YRP+ A PR + + + Q P A++ R+P
Sbjct: 172 SLSLIGGT------LLCLSCQDEAPYRPYQA--PPRATTTTANTAPAYQPPAAYKDNRAP 223
Query: 244 SDISSDVSIQMTQNY 258
S S+ S +Y
Sbjct: 224 SVTSATHSGYRLNDY 238
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 33.9 bits (76), Expect = 0.16
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 9/135 (6%)
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
P +T A + G FIL+GL +V + + + N S F F +S
Sbjct: 112 PAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISS 171
Query: 185 SFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQ-PEAWRRGRSP 243
S L G L +E YRP+ A PR + + + Q P A++ R+P
Sbjct: 172 SLSLIGGT------LLCLSCQDEAPYRPYQA--PPRATTTTANTAPAYQPPAAYKDNRAP 223
Query: 244 SDISSDVSIQMTQNY 258
S S+ S +Y
Sbjct: 224 SVTSATHSGYRLNDY 238
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 33.9 bits (76), Expect = 0.16
Identities = 38/188 (20%), Positives = 72/188 (38%), Gaps = 27/188 (14%)
Query: 20 GLLLVGIAVSTDYWLYMEEGTVLPQNQTTE-------VKMALHAGLWRVCFFAGREKGRC 72
GL L+G +++ W+ + T +PQ Q + A++ GLW C C
Sbjct: 5 GLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSC 64
Query: 73 VASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG--------HIR 124
+ L + ++ +VSL L F A ++ +G +
Sbjct: 65 KMYDSVLA------------LSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDK 112
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
++ +A GI FI++GL+ +V Y I + N + + + +A S
Sbjct: 113 VKKARIAMGGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGS 172
Query: 185 SFLLKEGA 192
+ ++ GA
Sbjct: 173 ALVILGGA 180
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 33.9 bits (76), Expect = 0.16
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 9/135 (6%)
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
P +T A + G FIL+GL +V + + + N S F F +S
Sbjct: 112 PAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISS 171
Query: 185 SFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQ-PEAWRRGRSP 243
S L G L +E YRP+ A PR + + + Q P A++ R+P
Sbjct: 172 SLSLIGGT------LLCLSCQDEAPYRPYQA--PPRATTTTANTAPAYQPPAAYKDNRAP 223
Query: 244 SDISSDVSIQMTQNY 258
S S+ S +Y
Sbjct: 224 SVTSATHSGYRLNDY 238
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 33.9 bits (76), Expect = 0.16
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 9/135 (6%)
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
P +T A + G FIL+GL +V + + + N S F F +S
Sbjct: 112 PAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISS 171
Query: 185 SFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQ-PEAWRRGRSP 243
S L G L +E YRP+ A PR + + + Q P A++ R+P
Sbjct: 172 SLSLIGGT------LLCLSCQDEAPYRPYQA--PPRATTTTANTAPAYQPPAAYKDNRAP 223
Query: 244 SDISSDVSIQMTQNY 258
S S+ S +Y
Sbjct: 224 SVTSATHSGYRLNDY 238
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 33.9 bits (76), Expect = 0.16
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 9/135 (6%)
Query: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184
P +T A + G FIL+GL +V + + + N S F F +S
Sbjct: 112 PAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISS 171
Query: 185 SFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQ-PEAWRRGRSP 243
S L G L +E YRP+ A PR + + + Q P A++ R+P
Sbjct: 172 SLSLIGGT------LLCLSCQDEAPYRPYQA--PPRATTTTANTAPAYQPPAAYKDNRAP 223
Query: 244 SDISSDVSIQMTQNY 258
S S+ S +Y
Sbjct: 224 SVTSATHSGYRLNDY 238
>gi|62000698 transmembrane protein 225 [Homo sapiens]
Length = 225
Score = 33.1 bits (74), Expect = 0.27
Identities = 36/197 (18%), Positives = 82/197 (41%), Gaps = 38/197 (19%)
Query: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
M H S+R++ ++ +F + ++L+ + ++ D W+ + + + + ++ W
Sbjct: 1 MVHVSNRSIQGMNILFSSWAVVLMVMGITLDKWVEL---------ISEDERAKMNHSPWM 51
Query: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
+C C A L PE +L +++ + T++ + L + +
Sbjct: 52 MC---------CPA----LWPEDDL------KVVRIMMTSS----LGLSFLLNLILGMKF 88
Query: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
++ PQ + + I SG+SL+ L+LY + + + S + +YR W
Sbjct: 89 TYLIPQNKYIQLFTTILSFFSGISLLWALILYHNKL------KQGQSMHFSNYRITWIMY 142
Query: 181 FAASSFLLKEGAGVMSV 197
A + GV+S+
Sbjct: 143 TAYLNVFFLSVCGVLSL 159
>gi|22027554 voltage-dependent calcium channel gamma-6 subunit
isoform a [Homo sapiens]
Length = 260
Score = 32.7 bits (73), Expect = 0.35
Identities = 47/207 (22%), Positives = 75/207 (36%), Gaps = 36/207 (17%)
Query: 12 LSSVFGACGLLLVGIAVSTDYWL----YMEEGTVLPQNQTTEVKMALHAGLWRVC----- 62
L+ + A G L ++V T++W+ Y G+ + + A H GLW+ C
Sbjct: 41 LALLLAAVGATLAVLSVGTEFWVELNTYKANGSAVCE--------AAHLGLWKACTKRLW 92
Query: 63 ---FFAGRE---------KGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFL 110
R+ + C ++F E + + T K V A V
Sbjct: 93 QADVPVDRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTK--KEVNLAAAVIAVLGLA 150
Query: 111 VFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSIN---DEVMNRPSSS 167
V + I + L V + F LSGL L+V L ++ S+ V P +
Sbjct: 151 VMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVRALLQRVSPEPPPA 210
Query: 168 EQYFHYRYGWSFAF-AASSFLLKEGAG 193
+ Y Y WS + +L GAG
Sbjct: 211 PR-LTYEYSWSLGCGVGAGLILLLGAG 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,371,676
Number of Sequences: 37866
Number of extensions: 439610
Number of successful extensions: 1335
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1295
Number of HSP's gapped (non-prelim): 56
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.