Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 21361639
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361639 DIPB protein [Homo sapiens]
(344 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361639 DIPB protein [Homo sapiens] 691 0.0
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 82 7e-16
gi|17975763 myelin transcription factor 1 [Homo sapiens] 75 7e-14
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 70 2e-12
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 70 2e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 70 2e-12
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 70 2e-12
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 70 2e-12
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 70 2e-12
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 70 2e-12
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 70 2e-12
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 70 2e-12
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 70 4e-12
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 70 4e-12
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 69 8e-12
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 68 1e-11
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 67 3e-11
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 65 7e-11
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 65 7e-11
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 65 7e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 65 9e-11
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 64 2e-10
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 64 2e-10
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 64 2e-10
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 64 2e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 64 2e-10
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 64 2e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 64 2e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 64 2e-10
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 64 2e-10
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 691 bits (1782), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MASGVGAAFEELPHDGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEY 60
MASGVGAAFEELPHDGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEY
Sbjct: 1 MASGVGAAFEELPHDGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEY 60
Query: 61 VHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDE 120
VHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDE
Sbjct: 61 VHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDE 120
Query: 121 SDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP 180
SDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP
Sbjct: 121 SDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP 180
Query: 181 DHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVER 240
DHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVER
Sbjct: 181 DHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVER 240
Query: 241 LKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQ 300
LKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQ
Sbjct: 241 LKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQ 300
Query: 301 SHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT 344
SHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT
Sbjct: 301 SHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT 344
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 82.0 bits (201), Expect = 7e-16
Identities = 52/111 (46%), Positives = 61/111 (54%), Gaps = 10/111 (9%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEA--------GEESESEEESESEE-ESETEEESEDESD 122
+GEG G+EE E + E E E GEE E E E E EE E E EEE E E +
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE 975
Query: 123 EESEEDSEEEMEDE-QESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E EEE E E +E E EE+ +EEGE E EGE E E E + E+E E E
Sbjct: 976 EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE 1026
Score = 74.7 bits (182), Expect = 1e-13
Identities = 48/107 (44%), Positives = 57/107 (53%), Gaps = 6/107 (5%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131
DGEG G+EE +E E E E EE E E E E E E E EE + +EE EE+ EE
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE-EGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Query: 132 EMEDEQESEAEEDNQEEGESEA-----EGETEAESEFDPEIEMEAER 173
E E E+E E E + +EEGE E EGE E E E E E E+
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
Score = 72.8 bits (177), Expect = 4e-13
Identities = 49/107 (45%), Positives = 60/107 (56%), Gaps = 7/107 (6%)
Query: 72 DGEGAGKEEAEVKVEQ---EREIESEAGEESESEEESESEEESETEEESEDESDEESEED 128
+GEG G+EE E + E+ E E E GE E E E E EEE E EEE E E +EE E +
Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020
Query: 129 SEEEMEDEQ---ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E+E E+ E E EE +E E E EGE E E+ + E E E E
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE-ENRRNREEEEEEE 1066
Score = 71.6 bits (174), Expect = 9e-13
Identities = 49/104 (47%), Positives = 58/104 (55%), Gaps = 7/104 (6%)
Query: 72 DGEGAGKEE-AEVKVEQ-EREIESEAGEESESEEESESEEESETE---EESEDESDEESE 126
+GEG G+EE E + E E E E E GE EEE E E E E E EE E E +EE
Sbjct: 927 EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG 986
Query: 127 EDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEME 170
E EE E E+E E E + +EEGE EGE E E E + E+E E
Sbjct: 987 EGEGEEEEGEEEGEEEGEGEEEGEG--EGEEEEEGEVEGEVEGE 1028
Score = 71.2 bits (173), Expect = 1e-12
Identities = 52/120 (43%), Positives = 62/120 (51%), Gaps = 11/120 (9%)
Query: 63 GSQAWTPPADGEGAGKEEAEV------KVEQ---EREIESEAGEESESEEESESEEESET 113
G Q + EG G+E+ E +VE+ ERE E E GE E E E E EE
Sbjct: 791 GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGE 850
Query: 114 EEESEDESDEESEEDSEEEMEDEQESEAEEDNQE-EGESEAEGETEAESEFDPEIEMEAE 172
EEE E + +EE EE EE +E E E EE+ E EGE E EGE E E E + E E E E
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE-EEEGEGEGEEEGE 909
Score = 70.1 bits (170), Expect = 3e-12
Identities = 50/105 (47%), Positives = 58/105 (55%), Gaps = 8/105 (7%)
Query: 73 GEGAGKEEAEVKVEQEREIESEAGEESES---EEESESEE---ESETEEESED-ESDEES 125
GE G E E K E+E E E GEE E EEE E EE E + EEE E+ E +EE
Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEG 871
Query: 126 EEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEME 170
EE E E+E E E EE+ + EGE E EGE E E E + E E E
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEE-EGEGEGEEEGEGEGEEE 915
Score = 69.7 bits (169), Expect = 4e-12
Identities = 44/104 (42%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEES--ESEEESETEEESEDESDEESEEDS 129
+GEG G+EE +E E E E EE E EEE E EEE E E E E E +E E
Sbjct: 976 EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE 1035
Query: 130 EEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
EEE E+E E +E EE E E E E ++ E E ER
Sbjct: 1036 EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENER 1079
Score = 68.9 bits (167), Expect = 6e-12
Identities = 49/103 (47%), Positives = 56/103 (54%), Gaps = 6/103 (5%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDE-ESEEDSE 130
+GEG G+EE E E E E E E GE EEE E E E E E E E+E E E EE+ E
Sbjct: 853 EGEGKGEEEGE---EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE 909
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGET-EAESEFDPEIEMEAE 172
E E+E+ E+ EEGE E E E E E E D E E E E
Sbjct: 910 GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE-DGEGEGEEE 951
Score = 68.6 bits (166), Expect = 8e-12
Identities = 51/106 (48%), Positives = 59/106 (55%), Gaps = 8/106 (7%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESE-TEEESEDESDEESEEDSE 130
+GEG G+EE E + E E E E E GEE E E E E E E E EEE E + +EE EE
Sbjct: 873 EGEGEGEEE-EGEGEGEEEGEGE-GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930
Query: 131 EEMEDEQESEAE----EDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E+E E E E E +EEGE E E E E E E + E E E E
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGE-EEEGEGEGEEEGEGEGE 975
Score = 67.0 bits (162), Expect = 2e-11
Identities = 43/90 (47%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Query: 74 EGAGKEEAEVKVEQEREIESEA-GEESESEEESESEEESETEEESEDESDEESEEDSEEE 132
EG G+EE E+E E + E GEE E EEE E E EEE E E +EE E + EEE
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898
Query: 133 MEDEQESEAEEDNQEEGESEAEGETEAESE 162
E E E EE+ + EGE E EGE + E E
Sbjct: 899 ---EGEGEGEEEGEGEGEEE-EGEGKGEEE 924
Score = 66.2 bits (160), Expect = 4e-11
Identities = 45/107 (42%), Positives = 54/107 (50%), Gaps = 7/107 (6%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESES------EEESETEEESEDESDEES 125
+GEG G+EE E + E+E E E E EE E E E E EE E E E E+E E
Sbjct: 882 EGEGEGEEEGEGEGEEE-EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940
Query: 126 EEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
ED E E E+E+ E+ + EGE E EGE E E E E E
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE 987
Score = 65.5 bits (158), Expect = 7e-11
Identities = 48/101 (47%), Positives = 52/101 (51%), Gaps = 8/101 (7%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEE-ESETEEESEDESDEESEEDSEEE 132
EG G+EE E + E E E E E E E E EE E E EEE E E +EE E EE
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923
Query: 133 MEDEQESEAEEDNQEEGESEAE-GETEAESEFDPEIEMEAE 172
+E E E EE EEGE E E GE E E E E E E E
Sbjct: 924 EGEEGEGEGEE---EEGEGEGEDGEGEGEEE---EGEWEGE 958
Score = 65.5 bits (158), Expect = 7e-11
Identities = 46/113 (40%), Positives = 61/113 (53%), Gaps = 11/113 (9%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEES------EDESDEES 125
+GEG G+EE E + E E E E E E E EEE E E E E E E E+E +EE
Sbjct: 985 EGEGEGEEE-EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG 1043
Query: 126 EEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
EE +E +E EE+ +EEG+ + GE E E + D E E ++V+K K
Sbjct: 1044 EEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ-DGE---EYKKVSKIK 1092
Score = 62.4 bits (150), Expect = 6e-10
Identities = 57/166 (34%), Positives = 69/166 (41%), Gaps = 21/166 (12%)
Query: 15 DGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE 74
+G +E E E G EE E E R+K E G + +
Sbjct: 742 EGDREEEEEKEGEGKEEGEGE--------EVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793
Query: 75 GAGKEEAEVKVEQEREI--ESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEE 132
G G+EE +E+E E E GE E + E E EEE EE E E +EE E EEE
Sbjct: 794 GEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853
Query: 133 MEDEQESEAEEDNQEEGESEAEGE------TEAESEFDPEIEMEAE 172
E + E E EE GE E EGE E E E + E E E E
Sbjct: 854 GEGKGEEEGEE-----GEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894
Score = 58.2 bits (139), Expect = 1e-08
Identities = 61/181 (33%), Positives = 77/181 (42%), Gaps = 15/181 (8%)
Query: 2 ASGVGAAFEELPH---DGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLA 58
A VG A E+ P DGTC+E +E RE G + E R LA
Sbjct: 641 AKSVGEA-EDGPEGRGDGTCEEGSSGAEHWQDEE-REKGE-KDKGRGEMERPGEGEKELA 697
Query: 59 EYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESE 118
E + W DGE ++E E ++ER E E G E E E E E + E EEE E
Sbjct: 698 E----KEEWKK-RDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752
Query: 119 DESDEESEEDSEEEMEDEQE-SEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
E EE E EE+E E+E E E +E E +GE E + E E E K
Sbjct: 753 GEGKEEGE---GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKE 809
Query: 178 K 178
+
Sbjct: 810 E 810
Score = 55.5 bits (132), Expect = 7e-08
Identities = 39/102 (38%), Positives = 52/102 (50%), Gaps = 5/102 (4%)
Query: 73 GEGAGKEEAEVKVEQEREIESEAGEESESEE-ESESE-EESETEEESEDESDEESEEDSE 130
GEG EE E E+E E E E EE E EE E E E EE E ++E +E+ EE+ +
Sbjct: 736 GEG---EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
+ +E+E+E + +EEG GE E E E E E
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE 834
Score = 50.8 bits (120), Expect = 2e-06
Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 72 DGEGAGK-EEAEVKVEQEREIESEAGEESESEEESESEEESETE---------EESEDES 121
+G G G EE E ++ E E GE+ + E E E E E + E++
Sbjct: 652 EGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQE 711
Query: 122 DEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPD 181
+E E+ ++E E E EE++ E E E + E E E E + + E E E V + +
Sbjct: 712 QKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKE 771
Query: 182 HG 183
G
Sbjct: 772 EG 773
Score = 49.7 bits (117), Expect = 4e-06
Identities = 36/102 (35%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133
E G+EE E+E + E E +E E +EE E EE E+ E E +E EE+
Sbjct: 728 EEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG 787
Query: 134 EDE-QESEAEEDNQE-EGESEAE-GETEAESEFDPEIEMEAE 172
E+E + E EE+ E GE + E GE E + + E E E
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Score = 37.7 bits (86), Expect = 0.015
Identities = 25/106 (23%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESES-EEESESEEESETEEESEDESDEESEEDSE 130
+GEG G+EE + +ERE E E E + EEE E E + + E E+E + E
Sbjct: 1029 EGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKV 1088
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAK 176
+++ + + Q++ + +G + + ++ ++++R+ K
Sbjct: 1089 SKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRS---KMPVQSKRLLK 1131
Score = 37.0 bits (84), Expect = 0.026
Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDS-----EEEM 133
++AEV + + + EA + E + EE S E +DE E+ E+D E
Sbjct: 632 DKAEVSEGKAKSV-GEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPG 690
Query: 134 EDEQE-SEAEEDNQEEGESEAEGETEAESEFDPEIEME 170
E E+E +E EE + +GE + + E E + + EME
Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME 728
Score = 36.6 bits (83), Expect = 0.034
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 21/122 (17%)
Query: 72 DGEGAGKEEAEVKVEQER-----------EIESEAGEESESEEESESEEESETEEESEDE 120
D +G G EE EV+ +E EI S+ + E +++ E E+ E
Sbjct: 595 DSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGR 654
Query: 121 SDEESEEDSE--EEMEDEQESEAEEDNQE-------EGESEAEGETEAESEFDPEIEMEA 171
D EE S E +DE+ + E+D EGE E E E + D E + +
Sbjct: 655 GDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL-AEKEEWKKRDGEEQEQK 713
Query: 172 ER 173
ER
Sbjct: 714 ER 715
Score = 33.9 bits (76), Expect = 0.22
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 7/107 (6%)
Query: 68 TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEES-----ETEEESEDESD 122
T PA A +E EV++ +E+E ++ E+E E+ EE+ +E++E SD
Sbjct: 570 TQPATTIEAFSDE-EVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSD 628
Query: 123 EESEEDSEEEMEDEQESEAEEDNQEEGESEA-EGETEAESEFDPEIE 168
+ +++ E + + EAE+ + G+ EG + AE D E E
Sbjct: 629 DLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEERE 675
Score = 31.2 bits (69), Expect = 1.4
Identities = 17/85 (20%), Positives = 39/85 (45%)
Query: 101 SEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAE 160
S + + ++++ E + E + D EEM + +E +A + + +G + T E
Sbjct: 518 SPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIE 577
Query: 161 SEFDPEIEMEAERVAKRKCPDHGLD 185
+ D E+E+ E+ +G++
Sbjct: 578 AFSDEEVEIPEEKEGAEDSKGNGIE 602
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 75.5 bits (184), Expect = 7e-14
Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 6/114 (5%)
Query: 70 PADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDS 129
P D E E EV E+ +++ ++ E++ SEE S+ + EEE E+E +EE EE+
Sbjct: 218 PEDAE----EVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEE 273
Query: 130 EEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI--EMEAERVAKRKCPD 181
+EE E+E+E E EE+ +EE E E E E E E E P++ + + + +K P+
Sbjct: 274 DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
Score = 67.4 bits (163), Expect = 2e-11
Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Query: 64 SQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDE 123
SQ P + + A +E ++ K E E E EE E EEE + EEE E EEE E+E +E
Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
Query: 124 ESEEDSEEEMEDEQESEAEEDNQEE-GESEAEGETEAESEFDPEIEMEAERVAKRKCPD 181
E EE+ EEE E+E+E+ + QE+ + A+ E P + E + + + D
Sbjct: 292 EEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDD 350
Score = 61.2 bits (147), Expect = 1e-09
Identities = 46/119 (38%), Positives = 61/119 (51%), Gaps = 12/119 (10%)
Query: 74 EGAGKEEAE----VKVEQEREIESEAGEESE-----SEEESESEEESETEEE-SEDESDE 123
EGA EE E ++ E E+ E S+ S E++ SEE S+ + S +E DE
Sbjct: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262
Query: 124 ESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
E EE EEE E+E E E EE+ +EE E E E E E E E + E E A V ++ H
Sbjct: 263 EEEE--EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319
Score = 48.9 bits (115), Expect = 7e-06
Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 6/145 (4%)
Query: 22 EPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEA 81
+P++A EV E C + E + S H + D E +EE
Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE------DEEEEEEEEE 270
Query: 82 EVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEA 141
E + E+E E E E EE E EEE E EEE E EEE E+ S + E
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRG 330
Query: 142 EEDNQEEGESEAEGETEAESEFDPE 166
E + E E ++ + D +
Sbjct: 331 PESPSPKPEYSVIVEVRSDDDKDED 355
Score = 46.2 bits (108), Expect = 4e-05
Identities = 36/110 (32%), Positives = 53/110 (48%), Gaps = 9/110 (8%)
Query: 93 SEAGEESESEEESESEEESE-TEEESEDE-----SDEESEEDSEEE---MEDEQESEAEE 143
SE GE+ + ++EE E T E S+D D SEE S+++ +E++ E EE
Sbjct: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEE 266
Query: 144 DNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ +EE E E E E E E E + E E E E + + + QED
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Score = 30.8 bits (68), Expect = 1.8
Identities = 51/264 (19%), Positives = 93/264 (35%), Gaps = 30/264 (11%)
Query: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQ 146
++R++E E S+ +S + + E D E E + + DE E E
Sbjct: 58 KKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEG--- 114
Query: 147 EEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGA 206
AE ET + E E K + + +T + G+
Sbjct: 115 ------AEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSK------------GS 156
Query: 207 HQGHQ------LSTLDEAFEE-LRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFI 259
+ +Q L L + EE L +D G +V L+ + + +FI
Sbjct: 157 YSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFI 216
Query: 260 QQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDT 319
Q E + + E + L +++A + + I SH + + + +E+ +
Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQ--KGILSHEEEDEEEEEEEEEEEED 274
Query: 320 SNESAEPKAEGDEEGPSGASEEED 343
E E + E +EE EEE+
Sbjct: 275 EEEEEEEEEEEEEEEEEEEEEEEE 298
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 70.5 bits (171), Expect = 2e-12
Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 275 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 333
Query: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
+++E E E ES + ++ E + E+
Sbjct: 334 EDEERENENHLLVVPESRFDRDSGESEEAEEEV 366
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE-----GAGKEEAEVKVEQEREIESEAG 96
RR AH + + + + +PP G G++ + + +ER++ S+
Sbjct: 196 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 255
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
+ S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +EE E E
Sbjct: 256 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 315
Query: 157 TEAESEFDPEIEMEAE 172
+E SE E E E
Sbjct: 316 SEEASEQSAEEVSEEE 331
Score = 67.0 bits (162), Expect = 2e-11
Identities = 64/208 (30%), Positives = 90/208 (43%), Gaps = 24/208 (11%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 252 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD---PEIEMEAERVAKRKC 179
E+ SE AEE ++EE + E E E ES FD E E E V +
Sbjct: 312 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTP 371
Query: 180 PDHGLDLSTYCQEDRQLICV-----LCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAM 234
L Y + L+ + L + A QG + E F+ L + G
Sbjct: 372 QSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV---EEFQCLNRIEEG-----T 423
Query: 235 IELVERLKFKSSDPKVTRDQMKMFIQQE 262
+V R K K +D V ++KM ++E
Sbjct: 424 YGVVYRAKDKKTDEIVALKRLKMEKEKE 451
Score = 33.9 bits (76), Expect = 0.22
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEF 163
+ E EE + + +D SD E + S E E S +EE+ +E E E E E +
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE----EEEEEEEGSTSE 296
Query: 164 DPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ E E E E + + + + S E+
Sbjct: 297 ESEEEEEEEEEEEEETGSNSEEASEQSAEE 326
Score = 32.0 bits (71), Expect = 0.83
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+E+ + + E ER+ E E S E + E+ E + E E + E+ +E E++ E+
Sbjct: 127 EEQDKARREWERQKRREMARE-HSRRERDRLEQLERKRERERKMREQQKEQREQK---ER 182
Query: 138 ESEAEEDNQEEGESEAEGETEA 159
E AEE +E EA E A
Sbjct: 183 ERRAEERRKER---EARREVSA 201
Score = 31.2 bits (69), Expect = 1.4
Identities = 55/305 (18%), Positives = 114/305 (37%), Gaps = 52/305 (17%)
Query: 78 KEEAEVKV---EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEED------ 128
+E+AE+K +R+ + ++ EE E + + ED ++ EED
Sbjct: 27 EEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIK 86
Query: 129 ---------------SEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
E+ E + + +E E + E + +A E++ + E R
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAR 146
Query: 174 VAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAA 233
R+ D L + +R++ + Q ++ E R+++ + A
Sbjct: 147 EHSRRERDRLEQLERKRERERKM-----------REQQKEQREQKERERRAEERRKEREA 195
Query: 234 MIEL--------------VERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALH 279
E+ V+ + S P+ R++ ++ ++ K +K+ +E
Sbjct: 196 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKM--EERDLLSD 253
Query: 280 LVDIQEA-MATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGA 338
L DI ++ T+ A+ S + + + +E+ TS ES E + E +EE
Sbjct: 254 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 313
Query: 339 SEEED 343
S E+
Sbjct: 314 SNSEE 318
Score = 30.4 bits (67), Expect = 2.4
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 11/80 (13%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESE-----------SEEESETEEESEDESDEES 125
G E+ KV+ EI E E EE++E S+ +S E E D E +
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
Query: 126 EEDSEEEMEDEQESEAEEDN 145
+S ED E EED+
Sbjct: 62 IRNSPYRREDSMEDRGEEDD 81
Score = 28.9 bits (63), Expect = 7.0
Identities = 51/258 (19%), Positives = 95/258 (36%), Gaps = 60/258 (23%)
Query: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQ 146
+ERE E E ++ E + E + + S E + + E + E+E + E +
Sbjct: 115 KEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQK 174
Query: 147 EEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGA 206
E+ E + E E AE E ER A+R+ + A
Sbjct: 175 EQREQK-ERERRAE-------ERRKEREARRE-------------------------VSA 201
Query: 207 HQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFIQQEFKKV 266
H +R S +KA+ + S P+ R++ ++ ++ K
Sbjct: 202 HH-----------RTMREDYSDKVKAS--------HWSRSPPRPPRERFELGDGRKPVKE 242
Query: 267 QKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEP 326
+K+ E++ L L D+Q+ + T + +S + + +E+ + E
Sbjct: 243 EKM----EERDL-LSDLQDISDSERKT---SSAESSSAESGSGSEEEEEEEEEEEEEGST 294
Query: 327 KAEGDEEGPSGASEEEDT 344
E +EE EEE+T
Sbjct: 295 SEESEEEEEEEEEEEEET 312
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 70.5 bits (171), Expect = 2e-12
Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 285 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 343
Query: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
+++E E E ES + ++ E + E+
Sbjct: 344 EDEERENENHLLVVPESRFDRDSGESEEAEEEV 376
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE-----GAGKEEAEVKVEQEREIESEAG 96
RR AH + + + + +PP G G++ + + +ER++ S+
Sbjct: 206 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 265
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
+ S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +EE E E
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 157 TEAESEFDPEIEMEAE 172
+E SE E E E
Sbjct: 326 SEEASEQSAEEVSEEE 341
Score = 67.0 bits (162), Expect = 2e-11
Identities = 64/208 (30%), Positives = 90/208 (43%), Gaps = 24/208 (11%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD---PEIEMEAERVAKRKC 179
E+ SE AEE ++EE + E E E ES FD E E E V +
Sbjct: 322 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTP 381
Query: 180 PDHGLDLSTYCQEDRQLICV-----LCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAM 234
L Y + L+ + L + A QG + E F+ L + G
Sbjct: 382 QSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV---EEFQCLNRIEEG-----T 433
Query: 235 IELVERLKFKSSDPKVTRDQMKMFIQQE 262
+V R K K +D V ++KM ++E
Sbjct: 434 YGVVYRAKDKKTDEIVALKRLKMEKEKE 461
Score = 33.9 bits (76), Expect = 0.22
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEF 163
+ E EE + + +D SD E + S E E S +EE+ +E E E E E +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE----EEEEEEEGSTSE 306
Query: 164 DPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ E E E E + + + + S E+
Sbjct: 307 ESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
Score = 33.1 bits (74), Expect = 0.37
Identities = 56/268 (20%), Positives = 105/268 (39%), Gaps = 42/268 (15%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K+E + + +E G+ + +E E + E +D++ E E EM E
Sbjct: 101 KDEKRKEKCRHHSHSAEGGKHARVKE--REHERRKRHREEQDKARREWERQKRREMARE- 157
Query: 138 ESEAEEDNQEEGESEAEGETE-AESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQL 196
S E D E+ E + E E + E + + + E ER A+ + + +E R+
Sbjct: 158 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE---------REARR- 207
Query: 197 ICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMK 256
+ AH +R S +KA+ + S P+ R++ +
Sbjct: 208 ------EVSAHH-----------RTMREDYSDKVKAS--------HWSRSPPRPPRERFE 242
Query: 257 MFIQQEFKKVQKVIADEEQKALHLVDIQEA-MATAHVTEILADIQSHMDRLMTQMAQAKE 315
+ ++ K +K+ +E L DI ++ T+ A+ S + + + +E
Sbjct: 243 LGDGRKPVKEEKM--EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 316 QLDTSNESAEPKAEGDEEGPSGASEEED 343
+ TS ES E + E +EE S E+
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEE 328
Score = 30.4 bits (67), Expect = 2.4
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 11/80 (13%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESE-----------SEEESETEEESEDESDEES 125
G E+ KV+ EI E E EE++E S+ +S E E D E +
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
Query: 126 EEDSEEEMEDEQESEAEEDN 145
+S ED E EED+
Sbjct: 62 IRNSPYRREDSMEDRGEEDD 81
Score = 30.0 bits (66), Expect = 3.2
Identities = 55/268 (20%), Positives = 99/268 (36%), Gaps = 63/268 (23%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136
G + A VK ERE E E ++ E + E + + S E + + E + E
Sbjct: 118 GGKHARVK---EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 174
Query: 137 QESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQL 196
+E + E +E+ E + E E AE E ER A+R+
Sbjct: 175 RERKMREQQKEQREQK-ERERRAE-------ERRKEREARRE------------------ 208
Query: 197 ICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMK 256
+ AH +R S +KA+ + S P+ R++ +
Sbjct: 209 -------VSAHH-----------RTMREDYSDKVKAS--------HWSRSPPRPPRERFE 242
Query: 257 MFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQ 316
+ ++ K +K+ E++ L L D+Q+ + T + +S + + +E+
Sbjct: 243 LGDGRKPVKEEKM----EERDL-LSDLQDISDSERKT---SSAESSSAESGSGSEEEEEE 294
Query: 317 LDTSNESAEPKAEGDEEGPSGASEEEDT 344
+ E E +EE EEE+T
Sbjct: 295 EEEEEEEGSTSEESEEEEEEEEEEEEET 322
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 70.5 bits (171), Expect = 2e-12
Identities = 38/78 (48%), Positives = 48/78 (61%)
Query: 93 SEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESE 152
+ + EE E EEE E EEE E EEE + E +EE EE+ EE E+E+E EE +EEGE E
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943
Query: 153 AEGETEAESEFDPEIEME 170
E E E E E + E+E
Sbjct: 944 EEEEEEDEEEEEELEEVE 961
Score = 70.1 bits (170), Expect = 3e-12
Identities = 44/98 (44%), Positives = 53/98 (54%), Gaps = 6/98 (6%)
Query: 68 TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESD----- 122
TP G A +E+ V + E E EE E EEE E EEE + EEE EDE +
Sbjct: 865 TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEE 924
Query: 123 EESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAE 160
EE EE+ EEE E E+E E EE+ +EE E E E E E
Sbjct: 925 EEEEEEFEEEFE-EEEGELEEEEEEEDEEEEEELEEVE 961
Score = 65.9 bits (159), Expect = 5e-11
Identities = 38/88 (43%), Positives = 50/88 (56%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D E +EE E + E+E E E + EE E EEE EEE E EE E+ +EE E + E
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGETE 158
EE EDE+E E E+ ++ A GE E
Sbjct: 946 EEEEDEEEEEELEEVEDLEFGTAGGEVE 973
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/75 (53%), Positives = 46/75 (61%), Gaps = 5/75 (6%)
Query: 105 SESEEESETEEESEDESDEESEEDSEEEMEDEQE-SEAEEDNQEEGESEAEGE----TEA 159
S+ EEE E EEE E+E +EE EED EEE EDE+E E EE+ +EE E E E E E
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945
Query: 160 ESEFDPEIEMEAERV 174
E E D E E E E V
Sbjct: 946 EEEEDEEEEEELEEV 960
Score = 65.5 bits (158), Expect = 7e-11
Identities = 40/86 (46%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEES--EEDSEEEMEDE 136
EE E + E+E E E E EE + EEE E EEE EEE E+E EE EE+ E E E+E
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 137 QESEAEEDNQEEGESEAEGETEAESE 162
+E E EE+ EE E G E E
Sbjct: 948 EEDEEEEEELEEVEDLEFGTAGGEVE 973
Score = 62.8 bits (151), Expect = 4e-10
Identities = 38/85 (44%), Positives = 50/85 (58%), Gaps = 3/85 (3%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEES---EEDSEEEME 134
+EE E + E+E E E E EE E +EE EEE E EEE E+E +EE EE+ EEE E
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
Query: 135 DEQESEAEEDNQEEGESEAEGETEA 159
+E+E E ++ E G + E E A
Sbjct: 952 EEEEELEEVEDLEFGTAGGEVEEGA 976
Score = 37.0 bits (84), Expect = 0.026
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 70 PADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESD-EESEED 128
P E G + A + + E E ES +E EE S + EE ED
Sbjct: 1012 PGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETED 1071
Query: 129 SEEEMEDEQESEAEEDNQEEGESEAEGETEAE 160
++++ E+ AEE+ + E E+EA E E +
Sbjct: 1072 GSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 70.5 bits (171), Expect = 2e-12
Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 276 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 334
Query: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
+++E E E ES + ++ E + E+
Sbjct: 335 EDEERENENHLLVVPESRFDRDSGESEEAEEEV 367
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE-----GAGKEEAEVKVEQEREIESEAG 96
RR AH + + + + +PP G G++ + + +ER++ S+
Sbjct: 197 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 256
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
+ S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +EE E E
Sbjct: 257 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 316
Query: 157 TEAESEFDPEIEMEAE 172
+E SE E E E
Sbjct: 317 SEEASEQSAEEVSEEE 332
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 253 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 312
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD 164
E+ SE AEE ++EE + E E E ES FD
Sbjct: 313 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFD 354
Score = 62.8 bits (151), Expect = 4e-10
Identities = 38/97 (39%), Positives = 46/97 (47%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
A AE E E E E EE E ESEEE E EEE E+E+ SEE SE+ E+
Sbjct: 268 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 327
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E ED + E E+ E+ + D EAE
Sbjct: 328 VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAE 364
Score = 52.4 bits (124), Expect = 6e-07
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 21/120 (17%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133
EG+ EE+E E+E EE E EEE+ S E +E+ +E+ S+EE ED E E
Sbjct: 292 EGSTSEESE---EEEE-------EEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 341
Query: 134 E-----------DEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
E D E+EE +E GE + E ++ P+ + K++ P +
Sbjct: 342 ENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKY 401
Score = 37.4 bits (85), Expect = 0.020
Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 11/106 (10%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K+ A VK E+ERE E E ++ E + E + + S E D E++E ++
Sbjct: 108 KKHARVK-EKEREHERRKRHREEQDKARREWERQKRREMAREHS--RRERDRLEQLERKR 164
Query: 138 ESEAE-EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
E E + + Q+E + E E AE E ER A+R+ H
Sbjct: 165 ERERKMREQQKEQREQKERERRAE-------ERRKEREARREVSAH 203
Score = 33.9 bits (76), Expect = 0.22
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEF 163
+ E EE + + +D SD E + S E E S +EE+ +E E E E E +
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE----EEEEEEEGSTSE 297
Query: 164 DPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ E E E E + + + + S E+
Sbjct: 298 ESEEEEEEEEEEEEETGSNSEEASEQSAEE 327
Score = 33.5 bits (75), Expect = 0.28
Identities = 50/265 (18%), Positives = 105/265 (39%), Gaps = 35/265 (13%)
Query: 94 EAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEA 153
+ GEE +S ++ S E+ + ++ E+ E E+E E + ++EE
Sbjct: 75 DRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE----- 129
Query: 154 EGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLS 213
+ +A E++ + E R R+ D L + +R++ + Q
Sbjct: 130 --QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM-----------REQQKE 176
Query: 214 TLDEAFEELRSKDSGGLKAAMIEL--------------VERLKFKSSDPKVTRDQMKMFI 259
++ E R+++ + A E+ V+ + S P+ R++ ++
Sbjct: 177 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 236
Query: 260 QQEFKKVQKVIADEEQKALHLVDIQEA-MATAHVTEILADIQSHMDRLMTQMAQAKEQLD 318
++ K +K+ +E L DI ++ T+ A+ S + + + +E+
Sbjct: 237 GRKPVKEEKM--EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 294
Query: 319 TSNESAEPKAEGDEEGPSGASEEED 343
TS ES E + E +EE S E+
Sbjct: 295 TSEESEEEEEEEEEEEEETGSNSEE 319
Score = 30.4 bits (67), Expect = 2.4
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 11/80 (13%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESE-----------SEEESETEEESEDESDEES 125
G E+ KV+ EI E E EE++E S+ +S E E D E +
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
Query: 126 EEDSEEEMEDEQESEAEEDN 145
+S ED E EED+
Sbjct: 62 IRNSPYRREDSMEDRGEEDD 81
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 70.5 bits (171), Expect = 2e-12
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 20/127 (15%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 285 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 343
Query: 135 DEQE-------------------SEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVA 175
+++E E+EE +E GE + E ++ P+ +
Sbjct: 344 EDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIEL 403
Query: 176 KRKCPDH 182
K++ P +
Sbjct: 404 KQELPKY 410
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE-----GAGKEEAEVKVEQEREIESEAG 96
RR AH + + + + +PP G G++ + + +ER++ S+
Sbjct: 206 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 265
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
+ S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +EE E E
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 157 TEAESEFDPEIEMEAE 172
+E SE E E E
Sbjct: 326 SEEASEQSAEEVSEEE 341
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD 164
E+ SE AEE ++EE + E E E ES FD
Sbjct: 322 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFD 363
Score = 62.8 bits (151), Expect = 4e-10
Identities = 38/97 (39%), Positives = 46/97 (47%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
A AE E E E E EE E ESEEE E EEE E+E+ SEE SE+ E+
Sbjct: 277 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E ED + E E+ E+ + D EAE
Sbjct: 337 VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAE 373
Score = 59.7 bits (143), Expect = 4e-09
Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 61 VHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE---- 116
+ S+ T A+ A + E+E E E E G SE EE E EEE E EEE
Sbjct: 267 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE-EEEEETGSN 325
Query: 117 SEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
SE+ S++ +EE SEEEM +++E E E ES + ++ E + E+
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEV 376
Score = 33.9 bits (76), Expect = 0.22
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEF 163
+ E EE + + +D SD E + S E E S +EE+ +E E E E E +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE----EEEEEEEGSTSE 306
Query: 164 DPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ E E E E + + + + S E+
Sbjct: 307 ESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
Score = 30.4 bits (67), Expect = 2.4
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 11/80 (13%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESE-----------SEEESETEEESEDESDEES 125
G E+ KV+ EI E E EE++E S+ +S E E D E +
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
Query: 126 EEDSEEEMEDEQESEAEEDN 145
+S ED E EED+
Sbjct: 62 IRNSPYRREDSMEDRGEEDD 81
Score = 30.4 bits (67), Expect = 2.4
Identities = 57/275 (20%), Positives = 102/275 (37%), Gaps = 68/275 (24%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE------- 130
K+ A VK E+ERE E E ++ E + E + + S E D
Sbjct: 108 KKHARVK-EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRL 166
Query: 131 EEMEDEQESEAE-EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTY 189
E++E ++E E + + Q+E + E E AE E ER A+R+
Sbjct: 167 EQLERKRERERKMREQQKEQREQKERERRAE-------ERRKEREARRE----------- 208
Query: 190 CQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPK 249
+ AH +R S +KA+ + S P+
Sbjct: 209 --------------VSAHH-----------RTMREDYSDKVKAS--------HWSRSPPR 235
Query: 250 VTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQ 309
R++ ++ ++ K +K+ E++ L L D+Q+ + T + +S +
Sbjct: 236 PPRERFELGDGRKPVKEEKM----EERDL-LSDLQDISDSERKT---SSAESSSAESGSG 287
Query: 310 MAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT 344
+ +E+ + E E +EE EEE+T
Sbjct: 288 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET 322
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 70.5 bits (171), Expect = 2e-12
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 20/127 (15%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 253 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 311
Query: 135 DEQE-------------------SEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVA 175
+++E E+EE +E GE + E ++ P+ +
Sbjct: 312 EDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIEL 371
Query: 176 KRKCPDH 182
K++ P +
Sbjct: 372 KQELPKY 378
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE-----GAGKEEAEVKVEQEREIESEAG 96
RR AH + + + + +PP G G++ + + +ER++ S+
Sbjct: 174 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 233
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
+ S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +EE E E
Sbjct: 234 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 293
Query: 157 TEAESEFDPEIEMEAE 172
+E SE E E E
Sbjct: 294 SEEASEQSAEEVSEEE 309
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 230 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 289
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD 164
E+ SE AEE ++EE + E E E ES FD
Sbjct: 290 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFD 331
Score = 62.8 bits (151), Expect = 4e-10
Identities = 38/97 (39%), Positives = 46/97 (47%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
A AE E E E E EE E ESEEE E EEE E+E+ SEE SE+ E+
Sbjct: 245 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 304
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E ED + E E+ E+ + D EAE
Sbjct: 305 VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAE 341
Score = 59.7 bits (143), Expect = 4e-09
Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 61 VHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE---- 116
+ S+ T A+ A + E+E E E E G SE EE E EEE E EEE
Sbjct: 235 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE-EEEEETGSN 293
Query: 117 SEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
SE+ S++ +EE SEEEM +++E E E ES + ++ E + E+
Sbjct: 294 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEV 344
Score = 42.0 bits (97), Expect = 8e-04
Identities = 57/268 (21%), Positives = 107/268 (39%), Gaps = 40/268 (14%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K+E + + R +E G+ + +E+ E + E +D++ E E EM E
Sbjct: 67 KDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMARE- 125
Query: 138 ESEAEEDNQEEGESEAEGETE-AESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQL 196
S E D E+ E + E E + E + + + E ER A+ + + +E R+
Sbjct: 126 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE---------REARR- 175
Query: 197 ICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMK 256
+ AH +R S +KA+ + S P+ R++ +
Sbjct: 176 ------EVSAHH-----------RTMREDYSDKVKAS--------HWSRSPPRPPRERFE 210
Query: 257 MFIQQEFKKVQKVIADEEQKALHLVDIQEA-MATAHVTEILADIQSHMDRLMTQMAQAKE 315
+ ++ K +K+ +E L DI ++ T+ A+ S + + + +E
Sbjct: 211 LGDGRKPVKEEKM--EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 268
Query: 316 QLDTSNESAEPKAEGDEEGPSGASEEED 343
+ TS ES E + E +EE S E+
Sbjct: 269 EGSTSEESEEEEEEEEEEEEETGSNSEE 296
Score = 37.0 bits (84), Expect = 0.026
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136
G + A VK E+ERE E E ++ E + E + + S E D E++E +
Sbjct: 84 GGKHARVK-EKEREHERRKRHREEQDKARREWERQKRREMAREHS--RRERDRLEQLERK 140
Query: 137 QESEAE-EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
+E E + + Q+E + E E AE E ER A+R+ H
Sbjct: 141 RERERKMREQQKEQREQKERERRAE-------ERRKEREARREVSAH 180
Score = 33.9 bits (76), Expect = 0.22
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEF 163
+ E EE + + +D SD E + S E E S +EE+ +E E E E E +
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE----EEEEEEEGSTSE 274
Query: 164 DPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ E E E E + + + + S E+
Sbjct: 275 ESEEEEEEEEEEEEETGSNSEEASEQSAEE 304
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 70.5 bits (171), Expect = 2e-12
Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 242 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 300
Query: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
+++E E E ES + ++ E + E+
Sbjct: 301 EDEERENENHLLVVPESRFDRDSGESEEAEEEV 333
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE-----GAGKEEAEVKVEQEREIESEAG 96
RR AH + + + + +PP G G++ + + +ER++ S+
Sbjct: 163 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 222
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
+ S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +EE E E
Sbjct: 223 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 282
Query: 157 TEAESEFDPEIEMEAE 172
+E SE E E E
Sbjct: 283 SEEASEQSAEEVSEEE 298
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 219 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 278
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD 164
E+ SE AEE ++EE + E E E ES FD
Sbjct: 279 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFD 320
Score = 62.8 bits (151), Expect = 4e-10
Identities = 38/97 (39%), Positives = 46/97 (47%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
A AE E E E E EE E ESEEE E EEE E+E+ SEE SE+ E+
Sbjct: 234 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 293
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E ED + E E+ E+ + D EAE
Sbjct: 294 VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAE 330
Score = 52.4 bits (124), Expect = 6e-07
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 21/120 (17%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133
EG+ EE+E E+E EE E EEE+ S E +E+ +E+ S+EE ED E E
Sbjct: 258 EGSTSEESE---EEEE-------EEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 307
Query: 134 E-----------DEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
E D E+EE +E GE + E ++ P+ + K++ P +
Sbjct: 308 ENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKY 367
Score = 37.4 bits (85), Expect = 0.020
Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 11/106 (10%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K+ A VK E+ERE E E ++ E + E + + S E D E++E ++
Sbjct: 74 KKHARVK-EKEREHERRKRHREEQDKARREWERQKRREMAREHS--RRERDRLEQLERKR 130
Query: 138 ESEAE-EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
E E + + Q+E + E E AE E ER A+R+ H
Sbjct: 131 ERERKMREQQKEQREQKERERRAE-------ERRKEREARREVSAH 169
Score = 33.9 bits (76), Expect = 0.22
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEF 163
+ E EE + + +D SD E + S E E S +EE+ +E E E E E +
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE----EEEEEEEGSTSE 263
Query: 164 DPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ E E E E + + + + S E+
Sbjct: 264 ESEEEEEEEEEEEEETGSNSEEASEQSAEE 293
Score = 33.5 bits (75), Expect = 0.28
Identities = 50/265 (18%), Positives = 105/265 (39%), Gaps = 35/265 (13%)
Query: 94 EAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEA 153
+ GEE +S ++ S E+ + ++ E+ E E+E E + ++EE
Sbjct: 41 DRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE----- 95
Query: 154 EGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLS 213
+ +A E++ + E R R+ D L + +R++ + Q
Sbjct: 96 --QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM-----------REQQKE 142
Query: 214 TLDEAFEELRSKDSGGLKAAMIEL--------------VERLKFKSSDPKVTRDQMKMFI 259
++ E R+++ + A E+ V+ + S P+ R++ ++
Sbjct: 143 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 202
Query: 260 QQEFKKVQKVIADEEQKALHLVDIQEA-MATAHVTEILADIQSHMDRLMTQMAQAKEQLD 318
++ K +K+ +E L DI ++ T+ A+ S + + + +E+
Sbjct: 203 GRKPVKEEKM--EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 260
Query: 319 TSNESAEPKAEGDEEGPSGASEEED 343
TS ES E + E +EE S E+
Sbjct: 261 TSEESEEEEEEEEEEEEETGSNSEE 285
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 70.5 bits (171), Expect = 2e-12
Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 31 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 89
Query: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
+++E E E ES + ++ E + E+
Sbjct: 90 EDEERENENHLLVVPESRFDRDSGESEEAEEEV 122
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 8 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 67
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD 164
E+ SE AEE ++EE + E E E ES FD
Sbjct: 68 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFD 109
Score = 63.5 bits (153), Expect = 3e-10
Identities = 37/85 (43%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
Query: 86 EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDN 145
+ ER+ S +ES SE EEE E EEE E + EESEE EEE E+E+E E ++
Sbjct: 15 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE--EEEEEEEEEEETGSNS 72
Query: 146 QEEGESEAEGETEAESEFDPEIEME 170
+E E AE +E E D E E E
Sbjct: 73 EEASEQSAEEVSEEEMSEDEERENE 97
Score = 62.8 bits (151), Expect = 4e-10
Identities = 34/86 (39%), Positives = 48/86 (55%)
Query: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQ 146
+ER++ S+ + S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 61
Query: 147 EEGESEAEGETEAESEFDPEIEMEAE 172
EE E E +E SE E E E
Sbjct: 62 EEEEEETGSNSEEASEQSAEEVSEEE 87
Score = 62.8 bits (151), Expect = 4e-10
Identities = 38/97 (39%), Positives = 46/97 (47%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
A AE E E E E EE E ESEEE E EEE E+E+ SEE SE+ E+
Sbjct: 23 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 82
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E ED + E E+ E+ + D EAE
Sbjct: 83 VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAE 119
Score = 58.9 bits (141), Expect = 6e-09
Identities = 30/80 (37%), Positives = 47/80 (58%)
Query: 99 SESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETE 158
S+ ++ S+SE ++ + E S ES SEE+ EEE E+E+E E+++EE E E E E E
Sbjct: 8 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 67
Query: 159 AESEFDPEIEMEAERVAKRK 178
S + E AE V++ +
Sbjct: 68 TGSNSEEASEQSAEEVSEEE 87
Score = 52.4 bits (124), Expect = 6e-07
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 21/120 (17%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133
EG+ EE+E E+E EE E EEE+ S E +E+ +E+ S+EE ED E E
Sbjct: 47 EGSTSEESE---EEEE-------EEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 96
Query: 134 E-----------DEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
E D E+EE +E GE + E ++ P+ + K++ P +
Sbjct: 97 ENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKY 156
Score = 50.1 bits (118), Expect = 3e-06
Identities = 29/80 (36%), Positives = 40/80 (50%)
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
EE + + + +SE + S + S ES SEEE E+E+E E E EE E E E E
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 61
Query: 157 TEAESEFDPEIEMEAERVAK 176
E E E E +E+ A+
Sbjct: 62 EEEEEETGSNSEEASEQSAE 81
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 70.5 bits (171), Expect = 2e-12
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 20/127 (15%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G+G EE E + E+E E E EESE EEE E EEE ET SE+ S++ +EE SEEEM
Sbjct: 287 GSGSEEEEEEEEEEEE-EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 345
Query: 135 DEQE-------------------SEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVA 175
+++E E+EE +E GE + E ++ P+ +
Sbjct: 346 EDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIEL 405
Query: 176 KRKCPDH 182
K++ P +
Sbjct: 406 KQELPKY 412
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGE-----GAGKEEAEVKVEQEREIESEAG 96
RR AH + + + + +PP G G++ + + +ER++ S+
Sbjct: 208 RREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 267
Query: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
+ S+SE ++ S E S E S E +EE EE+ EEE +ESE EE+ +EE E E
Sbjct: 268 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 327
Query: 157 TEAESEFDPEIEMEAE 172
+E SE E E E
Sbjct: 328 SEEASEQSAEEVSEEE 343
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
+D + E + + ES +G E E EEE E EEE T EESE+E +EE EE+ E
Sbjct: 264 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 323
Query: 131 EEMEDEQESE--AEEDNQEEGESEAEGETE------AESEFD 164
E+ SE AEE ++EE + E E E ES FD
Sbjct: 324 TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFD 365
Score = 62.8 bits (151), Expect = 4e-10
Identities = 38/97 (39%), Positives = 46/97 (47%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
A AE E E E E EE E ESEEE E EEE E+E+ SEE SE+ E+
Sbjct: 279 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 338
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E ED + E E+ E+ + D EAE
Sbjct: 339 VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAE 375
Score = 59.7 bits (143), Expect = 4e-09
Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 61 VHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE---- 116
+ S+ T A+ A + E+E E E E G SE EE E EEE E EEE
Sbjct: 269 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE-EEEEETGSN 327
Query: 117 SEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
SE+ S++ +EE SEEEM +++E E E ES + ++ E + E+
Sbjct: 328 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEV 378
Score = 42.0 bits (97), Expect = 8e-04
Identities = 57/268 (21%), Positives = 107/268 (39%), Gaps = 40/268 (14%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K+E + + R +E G+ + +E+ E + E +D++ E E EM E
Sbjct: 101 KDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMARE- 159
Query: 138 ESEAEEDNQEEGESEAEGETE-AESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQL 196
S E D E+ E + E E + E + + + E ER A+ + + +E R+
Sbjct: 160 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE---------REARR- 209
Query: 197 ICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMK 256
+ AH +R S +KA+ + S P+ R++ +
Sbjct: 210 ------EVSAHH-----------RTMREDYSDKVKAS--------HWSRSPPRPPRERFE 244
Query: 257 MFIQQEFKKVQKVIADEEQKALHLVDIQEA-MATAHVTEILADIQSHMDRLMTQMAQAKE 315
+ ++ K +K+ +E L DI ++ T+ A+ S + + + +E
Sbjct: 245 LGDGRKPVKEEKM--EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 302
Query: 316 QLDTSNESAEPKAEGDEEGPSGASEEED 343
+ TS ES E + E +EE S E+
Sbjct: 303 EGSTSEESEEEEEEEEEEEEETGSNSEE 330
Score = 37.0 bits (84), Expect = 0.026
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136
G + A VK E+ERE E E ++ E + E + + S E D E++E +
Sbjct: 118 GGKHARVK-EKEREHERRKRHREEQDKARREWERQKRREMAREHS--RRERDRLEQLERK 174
Query: 137 QESEAE-EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDH 182
+E E + + Q+E + E E AE E ER A+R+ H
Sbjct: 175 RERERKMREQQKEQREQKERERRAE-------ERRKEREARREVSAH 214
Score = 33.9 bits (76), Expect = 0.22
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEF 163
+ E EE + + +D SD E + S E E S +EE+ +E E E E E +
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE----EEEEEEEGSTSE 308
Query: 164 DPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
+ E E E E + + + + S E+
Sbjct: 309 ESEEEEEEEEEEEEETGSNSEEASEQSAEE 338
Score = 30.4 bits (67), Expect = 2.4
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 11/80 (13%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESE-----------SEEESETEEESEDESDEES 125
G E+ KV+ EI E E EE++E S+ +S E E D E +
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
Query: 126 EEDSEEEMEDEQESEAEEDN 145
+S ED E EED+
Sbjct: 62 IRNSPYRREDSMEDRGEEDD 81
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 69.7 bits (169), Expect = 4e-12
Identities = 46/111 (41%), Positives = 64/111 (57%), Gaps = 10/111 (9%)
Query: 78 KEEAEVKVEQ-EREIESEAGEESE--------SEEESESEEESETEEESEDESDEESEED 128
KE AE K E+ E E E A ++S EEE E EEE EEE E++ +S++
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 129 SEEEMEDEQESEAEEDNQEEGESEAEGE-TEAESEFDPEIEMEAERVAKRK 178
E E E SE EE QEEGE+EAE E EAE++ + ++E ++E VA ++
Sbjct: 549 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 599
Score = 62.0 bits (149), Expect = 7e-10
Identities = 40/100 (40%), Positives = 54/100 (54%), Gaps = 9/100 (9%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138
EE V +++E++ EA EE E E E+E EE + + + + E EE+ E+E E+ QE
Sbjct: 478 EELAVSMKEEKK---EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQE 534
Query: 139 SEAEE------DNQEEGESEAEGETEAESEFDPEIEMEAE 172
E EE D EEG SE EG +E E E E EAE
Sbjct: 535 EEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE 574
Score = 60.1 bits (144), Expect = 3e-09
Identities = 37/118 (31%), Positives = 57/118 (48%), Gaps = 6/118 (5%)
Query: 69 PPADGEGAGKEEAEVKV------EQEREIESEAGEESESEEESESEEESETEEESEDESD 122
P A+ E +++ VK E+E E E E G+E E EE+ ++ + E SE E
Sbjct: 499 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 558
Query: 123 EESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP 180
E EE +EE E E E+E EE +E + E E ++ + + + E+ K K P
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 616
Score = 52.0 bits (123), Expect = 8e-07
Identities = 71/303 (23%), Positives = 121/303 (39%), Gaps = 42/303 (13%)
Query: 65 QAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEE 124
+A P E KEE E + E+E E E +++E E SE E SE EE ++E + E
Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE-EGGSEKEGSSEKEEGEQEEGETE 572
Query: 125 SEEDSEEEMEDEQESEAEEDNQEEGESE---AEGETE-AESEFDPEIEMEAERVAKRKCP 180
+E + EE E ++E + EE ++E E A+ + E E P + E K P
Sbjct: 573 AEAEG-EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 181 DHGLD-------LSTYCQEDRQLICVLCPVIGAHQGH-QLSTLDE---------AFEELR 223
++ + +E + PV + S ++E EE +
Sbjct: 632 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 691
Query: 224 SKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDI 283
SK G E + +K + KV + + K E KK + + +E
Sbjct: 692 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE---------- 741
Query: 284 QEAMATAHVTEILADIQSHMDRLMTQ----MAQAKEQLDTSNESAEPKAEGDEEGPSGAS 339
A A V I ++ H+++ + + Q KE+ E + EG ++G G+
Sbjct: 742 ----AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGS-EEEGSDKGAKGSR 796
Query: 340 EEE 342
+E+
Sbjct: 797 KED 799
Score = 45.1 bits (105), Expect = 9e-05
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 82 EVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEA 141
E KVE E+ E E + +EE + S +E + E E E + E+EE+ + ++ A
Sbjct: 459 ETKVEDEKS-EMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517
Query: 142 EEDNQEEGESEAE-GETEAESEFDPEIEMEAERVAKRK 178
E +EEGE E E G+ E E E + +AE K
Sbjct: 518 PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEK 555
Score = 40.8 bits (94), Expect = 0.002
Identities = 32/101 (31%), Positives = 44/101 (43%), Gaps = 14/101 (13%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K EA Q + +E E +E+SE EE E S +E ++++ EE E+E
Sbjct: 440 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 499
Query: 138 ESEAE--------------EDNQEEGESEAEGETEAESEFD 164
E+E E E +EEGE E E E E E D
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED 540
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/149 (28%), Positives = 67/149 (44%), Gaps = 24/149 (16%)
Query: 58 AEYVHGSQAWTPPADGEGAGKEE-AEVKVEQEREIESEAGEESESEEESESEE------- 109
AE G Q + + A KEE E K E+ +++ + ES +EE+ +E
Sbjct: 694 AEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSV 753
Query: 110 ----ESETEEESEDESDEESEE------DSEEEMEDE-QESEAEEDNQEEGESEAEGETE 158
E ET+EE + E+ +E SEEE D+ + +ED GE E + E E
Sbjct: 754 KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE 813
Query: 159 AESEFDPEIEMEAERVAKRKCPDHGLDLS 187
E++ E + R ++ +GLDLS
Sbjct: 814 QETK-----EKGSGREEEKGVVTNGLDLS 837
Score = 32.3 bits (72), Expect = 0.63
Identities = 49/219 (22%), Positives = 87/219 (39%), Gaps = 31/219 (14%)
Query: 118 EDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
E+ +E ED + EME+ + E E S E + EA E + E E E E VA +
Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITE----ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAK 509
Query: 178 KCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIEL 237
K P + P + +G + +E EE +D G E
Sbjct: 510 KSP----------------VKATAPEVKEEEGEKEE--EEGQEEEEEEDEGAKSDQAEEG 551
Query: 238 VERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILA 297
+ S + +++ + + E ++ + A EE+K + + E +AT E++A
Sbjct: 552 GSEKEGSSEKEEGEQEEGETEAEAEGEEAE---AKEEKK---VEEKSEEVATKE--ELVA 603
Query: 298 DIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPS 336
D + + K ++ +S PK+ +E+G S
Sbjct: 604 DAKVEKPE-KAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 641
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 69.7 bits (169), Expect = 4e-12
Identities = 46/111 (41%), Positives = 64/111 (57%), Gaps = 10/111 (9%)
Query: 78 KEEAEVKVEQ-EREIESEAGEESE--------SEEESESEEESETEEESEDESDEESEED 128
KE AE K E+ E E E A ++S EEE E EEE EEE E++ +S++
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 172
Query: 129 SEEEMEDEQESEAEEDNQEEGESEAEGE-TEAESEFDPEIEMEAERVAKRK 178
E E E SE EE QEEGE+EAE E EAE++ + ++E ++E VA ++
Sbjct: 173 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 223
Score = 62.0 bits (149), Expect = 7e-10
Identities = 40/100 (40%), Positives = 54/100 (54%), Gaps = 9/100 (9%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138
EE V +++E++ EA EE E E E+E EE + + + + E EE+ E+E E+ QE
Sbjct: 102 EELAVSMKEEKK---EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQE 158
Query: 139 SEAEE------DNQEEGESEAEGETEAESEFDPEIEMEAE 172
E EE D EEG SE EG +E E E E EAE
Sbjct: 159 EEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE 198
Score = 60.1 bits (144), Expect = 3e-09
Identities = 37/118 (31%), Positives = 57/118 (48%), Gaps = 6/118 (5%)
Query: 69 PPADGEGAGKEEAEVKV------EQEREIESEAGEESESEEESESEEESETEEESEDESD 122
P A+ E +++ VK E+E E E E G+E E EE+ ++ + E SE E
Sbjct: 123 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 182
Query: 123 EESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP 180
E EE +EE E E E+E EE +E + E E ++ + + + E+ K K P
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 240
Score = 52.0 bits (123), Expect = 8e-07
Identities = 71/303 (23%), Positives = 121/303 (39%), Gaps = 42/303 (13%)
Query: 65 QAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEE 124
+A P E KEE E + E+E E E +++E E SE E SE EE ++E + E
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE-EGGSEKEGSSEKEEGEQEEGETE 196
Query: 125 SEEDSEEEMEDEQESEAEEDNQEEGESE---AEGETE-AESEFDPEIEMEAERVAKRKCP 180
+E + EE E ++E + EE ++E E A+ + E E P + E K P
Sbjct: 197 AEAEG-EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 255
Query: 181 DHGLD-------LSTYCQEDRQLICVLCPVIGAHQGH-QLSTLDE---------AFEELR 223
++ + +E + PV + S ++E EE +
Sbjct: 256 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 315
Query: 224 SKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDI 283
SK G E + +K + KV + + K E KK + + +E
Sbjct: 316 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE---------- 365
Query: 284 QEAMATAHVTEILADIQSHMDRLMTQ----MAQAKEQLDTSNESAEPKAEGDEEGPSGAS 339
A A V I ++ H+++ + + Q KE+ E + EG ++G G+
Sbjct: 366 ----AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGS-EEEGSDKGAKGSR 420
Query: 340 EEE 342
+E+
Sbjct: 421 KED 423
Score = 45.1 bits (105), Expect = 9e-05
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 82 EVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEA 141
E KVE E+ E E + +EE + S +E + E E E + E+EE+ + ++ A
Sbjct: 83 ETKVEDEKS-EMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141
Query: 142 EEDNQEEGESEAE-GETEAESEFDPEIEMEAERVAKRK 178
E +EEGE E E G+ E E E + +AE K
Sbjct: 142 PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEK 179
Score = 40.8 bits (94), Expect = 0.002
Identities = 32/101 (31%), Positives = 44/101 (43%), Gaps = 14/101 (13%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K EA Q + +E E +E+SE EE E S +E ++++ EE E+E
Sbjct: 64 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 123
Query: 138 ESEAE--------------EDNQEEGESEAEGETEAESEFD 164
E+E E E +EEGE E E E E E D
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED 164
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/149 (28%), Positives = 67/149 (44%), Gaps = 24/149 (16%)
Query: 58 AEYVHGSQAWTPPADGEGAGKEE-AEVKVEQEREIESEAGEESESEEESESEE------- 109
AE G Q + + A KEE E K E+ +++ + ES +EE+ +E
Sbjct: 318 AEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSV 377
Query: 110 ----ESETEEESEDESDEESEE------DSEEEMEDE-QESEAEEDNQEEGESEAEGETE 158
E ET+EE + E+ +E SEEE D+ + +ED GE E + E E
Sbjct: 378 KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE 437
Query: 159 AESEFDPEIEMEAERVAKRKCPDHGLDLS 187
E++ E + R ++ +GLDLS
Sbjct: 438 QETK-----EKGSGREEEKGVVTNGLDLS 461
Score = 32.3 bits (72), Expect = 0.63
Identities = 49/219 (22%), Positives = 87/219 (39%), Gaps = 31/219 (14%)
Query: 118 EDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
E+ +E ED + EME+ + E E S E + EA E + E E E E VA +
Sbjct: 78 EEIIEETKVEDEKSEMEEALTAITE----ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAK 133
Query: 178 KCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIEL 237
K P + P + +G + +E EE +D G E
Sbjct: 134 KSP----------------VKATAPEVKEEEGEKEE--EEGQEEEEEEDEGAKSDQAEEG 175
Query: 238 VERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILA 297
+ S + +++ + + E ++ + A EE+K + + E +AT E++A
Sbjct: 176 GSEKEGSSEKEEGEQEEGETEAEAEGEEAE---AKEEKK---VEEKSEEVATKE--ELVA 227
Query: 298 DIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPS 336
D + + K ++ +S PK+ +E+G S
Sbjct: 228 DAKVEKPE-KAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 265
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 68.6 bits (166), Expect = 8e-12
Identities = 42/111 (37%), Positives = 60/111 (54%), Gaps = 5/111 (4%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESE-DESDEESEEDS 129
+DG E+ E + E+ E E G+E E +EE + EEE E EEE E D+ D E ED
Sbjct: 93 SDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152
Query: 130 EEEMEDEQESEAEEDNQEE----GESEAEGETEAESEFDPEIEMEAERVAK 176
EEE E+E+E E EE+N++ + +TE + + E + E VAK
Sbjct: 153 EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203
Score = 62.4 bits (150), Expect = 6e-10
Identities = 34/78 (43%), Positives = 47/78 (60%), Gaps = 7/78 (8%)
Query: 92 ESEAGEESESEEESESEEESETEEE--SEDESDEESEEDSEEEMEDEQESEAE-----ED 144
+S+ E+ + +EE E EE SE +E EDE DEE + + EEE+E+E E + E ED
Sbjct: 92 DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151
Query: 145 NQEEGESEAEGETEAESE 162
+EE E E E E E E+E
Sbjct: 152 EEEEEEEEEEEEEEEENE 169
Score = 58.9 bits (141), Expect = 6e-09
Identities = 34/79 (43%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 97 EESESEEESESEEESETEEESED--ESDEESEEDSEEEMEDEQESEAE-EDNQEEGESEA 153
++S+ E+ + +EE E EE SED E +E EED E + E+E+E E E ED+ E+GE
Sbjct: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVE 150
Query: 154 EGETEAESEFDPEIEMEAE 172
+ E E E E + E E E E
Sbjct: 151 DEEEEEEEEEEEEEEEENE 169
Score = 52.0 bits (123), Expect = 8e-07
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 13/127 (10%)
Query: 76 AGKEEAEVKVEQE----REIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131
A K + + K QE R+ + + S +E +S+ + +E+ EDE +E SE++ E
Sbjct: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117
Query: 132 EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQ 191
EDE++ E + + +EE E E E + E + + E E E E + + ++
Sbjct: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN--------- 168
Query: 192 EDRQLIC 198
ED Q+ C
Sbjct: 169 EDHQMNC 175
Score = 48.5 bits (114), Expect = 9e-06
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+E+ E E+E EIE E ++ E E+ E EEE E EEE E+E +EE+E+
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE-EEEEEEEEEEENEDHQMNCHNTRI 180
Query: 138 ESEAEEDNQEEGESEAEGETEAES 161
+ E+D+ E + E A+S
Sbjct: 181 MQDTEKDDNNNDEYDNYDELVAKS 204
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 67.8 bits (164), Expect = 1e-11
Identities = 50/192 (26%), Positives = 87/192 (45%), Gaps = 8/192 (4%)
Query: 59 EYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE-S 117
E V+ + + G +E E E E G E + EE+ E EE++E +EE
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEE-----GVEEDVEEDEEVEEDAEEDEEVD 226
Query: 118 EDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
ED +EE EE+ EEE E+E+E E E+D +++ E + +T +E+ + + R
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286
Query: 178 KCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIEL 237
G D S +++R+ + P++ G S E+ K S ++A +
Sbjct: 287 S--GSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQ 344
Query: 238 VERLKFKSSDPK 249
+LK+ D +
Sbjct: 345 TSKLKYVLQDAR 356
Score = 33.9 bits (76), Expect = 0.22
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 13/98 (13%)
Query: 84 KVEQEREIESEAGEESE------SEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K + ER +S + SE S S + S+ E SE+ + E DEQ
Sbjct: 137 KRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH--ETGSSGSSDEQ 194
Query: 138 ESEAEEDNQEEG---ESEAEGETEAESEFDPEIEMEAE 172
+ E N+EEG + E + E E ++E D E++ + E
Sbjct: 195 GNNTE--NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 66.6 bits (161), Expect = 3e-11
Identities = 35/99 (35%), Positives = 56/99 (56%)
Query: 80 EAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQES 139
E E + E+ERE E E +E E E+E E + E + E+E E E ++E + + E+E + E+E
Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
Query: 140 EAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
E E ++E E + E E E E + E E E++ R+
Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPRE 604
Score = 66.2 bits (160), Expect = 4e-11
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 2/100 (2%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+E E + E+ERE E E +E E E E E E++ E ++E E E ++E E+ E E E +Q
Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
E E E + Q+E E E + E E E E+E E E++ ++
Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKEC--ELEKEREKLEEK 599
Score = 63.5 bits (153), Expect = 3e-10
Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 4/104 (3%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133
E G E + E+ RE E E E E E E E E+E E E E + E +E E++ E+E
Sbjct: 490 EKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549
Query: 134 EDEQESEAEEDNQEEGESEAEGETEAE----SEFDPEIEMEAER 173
E ++E E E ++E E E + E E E E + E E+E ER
Sbjct: 550 EKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER 593
Score = 62.4 bits (150), Expect = 6e-10
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 18/119 (15%)
Query: 78 KEEAEVKVEQERE----------------IESEAGEES--ESEEESESEEESETEEESED 119
+EE E ++E++R+ +E + E E E E E E E E E+E E
Sbjct: 466 REEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQ 525
Query: 120 ESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
E ++E E+D E + E E+E E E++ Q E E E + E E E E E E E +++ +++
Sbjct: 526 EREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQE 584
Score = 59.7 bits (143), Expect = 4e-09
Identities = 34/95 (35%), Positives = 52/95 (54%)
Query: 68 TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEE 127
+P E ++E E + E E+E E E +E E + E + E+E E E+E E + + E E
Sbjct: 500 SPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKER 559
Query: 128 DSEEEMEDEQESEAEEDNQEEGESEAEGETEAESE 162
E+E E E++ E E++ Q+ E E E E E E E
Sbjct: 560 KQEKEKELERQKEKEKELQKMKEQEKECELEKERE 594
Score = 59.3 bits (142), Expect = 5e-09
Identities = 30/92 (32%), Positives = 51/92 (55%)
Query: 88 EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQE 147
E++ E E E E+E E E+E E E+E E E + E + + ++E E E E E E+ +
Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555
Query: 148 EGESEAEGETEAESEFDPEIEMEAERVAKRKC 179
E E + E E E E + + E E++ + +++C
Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKEC 587
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
Query: 78 KEEAEVKVEQEREIESEAGEE--SESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
++E E + EQERE E E E E E+E E E+E + E E E + ++E E + ++E E
Sbjct: 516 EKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEK 575
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
E + E++ + E E E E E +P +E E+
Sbjct: 576 ELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK 613
Score = 53.5 bits (127), Expect = 3e-07
Identities = 27/93 (29%), Positives = 52/93 (55%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
++E E + E+E++ E + +E E E+E E + E E E + E E + E +++ E+E++ +
Sbjct: 522 EQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMK 581
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEME 170
E E E + ++E E E E +P +E +
Sbjct: 582 EQEKECELEKEREKLEEKIEPREPNLEPMVEKQ 614
Score = 50.4 bits (119), Expect = 2e-06
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131
D E ++E E++ EQE++ E E + E E+E E ++E E E + E ++E E + E
Sbjct: 534 DRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER 593
Query: 132 EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI-EMEAERVAKRKCP 180
E + E++ E E N E + E E E +P ++ R K P
Sbjct: 594 E-KLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATP 642
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Query: 80 EAEVKVEQEREIESEAGEESESEEESESEEESETEEESED-ESDEESEEDSEEEMEDEQE 138
E E K E+E+E+E + +E E ++ E E+E E E+E E E E E + E M ++QE
Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQE 615
Query: 139 SEAEEDNQEEGESEAEGETEAESEFDPEI-EMEAE 172
SE + +EE + +E E P + E E E
Sbjct: 616 SENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
Score = 48.9 bits (115), Expect = 7e-06
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 26/119 (21%)
Query: 86 EQEREIESEAGEESESEEESESEEESETEE--------------------------ESED 119
+Q R +SE E + EEE EE E
Sbjct: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505
Query: 120 ESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
E + E E + E+E+E EQE E E++ +++ E + E E E E E + + EME ER +++
Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564
Score = 46.2 bits (108), Expect = 4e-05
Identities = 32/128 (25%), Positives = 64/128 (50%), Gaps = 9/128 (7%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESES---EEESETEE-----ESEDESDEESEEDS 129
++++E+ ER + EE EE+ ++ E+ +E E + +E E +
Sbjct: 450 RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
Query: 130 EEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER-VAKRKCPDHGLDLST 188
E+E E E+E E E++ + E E E + E + E E + E E E +R + K + + +L
Sbjct: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
Query: 189 YCQEDRQL 196
+++++L
Sbjct: 570 QKEKEKEL 577
Score = 37.0 bits (84), Expect = 0.026
Identities = 22/108 (20%), Positives = 51/108 (47%), Gaps = 2/108 (1%)
Query: 57 LAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEE--ESESEEESETE 114
L+E G + PP + + + + +E++ ++E++E E TE
Sbjct: 271 LSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTE 330
Query: 115 EESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESE 162
+ + + DE+ +E ++Q S+A E+N+ + E++ T++ S+
Sbjct: 331 QLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQ 378
Score = 37.0 bits (84), Expect = 0.026
Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 78 KEEAEVKVEQEREIES--EAGEESESEEESES-EEESETEEESEDESDEESEEDSEEEME 134
++E E + E+E+E++ E +E E E+E E EE+ E E + + E+ E ++ E
Sbjct: 564 EKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKE 623
Query: 135 DEQESEAEEDNQEEGE-SEAEGETEAESEFDP 165
+E ++ N+ E E + ETE ES P
Sbjct: 624 EEPVFTRQDSNRSEKEATPVVHETEPESGSQP 655
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 65.5 bits (158), Expect = 7e-11
Identities = 32/92 (34%), Positives = 55/92 (59%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
A+ +G +EE + + E E + + E GEE E +EE + +E+ E +E+ ++ S+EE E +
Sbjct: 160 AEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLD 219
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGETEAESE 162
EE EDE E E EE+ + + + E + E E +
Sbjct: 220 EEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 61.2 bits (147), Expect = 1e-09
Identities = 35/101 (34%), Positives = 57/101 (56%), Gaps = 2/101 (1%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131
+ + A +AEV E E E E GE+ E E++ + EEE E +EE +++ D E +ED +E
Sbjct: 151 EDQEAPDSDAEVDGVDEEE-EDEEGEDEEDEDDEDGEEE-EFDEEDDEDEDVEGDEDDDE 208
Query: 132 EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E+E+E +E++++E E E E E + E + E E
Sbjct: 209 VSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGE 249
Score = 58.5 bits (140), Expect = 8e-09
Identities = 30/93 (32%), Positives = 51/93 (54%)
Query: 86 EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDN 145
++E + ++ E + +E E +EE E EE+ +DE EE E D E++ +++ E + ++D
Sbjct: 149 DREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDE 208
Query: 146 QEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
E E E + E E E + E E E + KRK
Sbjct: 209 VSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRK 241
Score = 58.5 bits (140), Expect = 8e-09
Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 6/99 (6%)
Query: 69 PPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEE-ESEDESDEESEE 127
P +D E G +E E E E + E ++ + EEE EE+ E E+ E +++ DE SEE
Sbjct: 156 PDSDAEVDGVDEEE---EDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEE 212
Query: 128 DSEEEMEDEQESEAEEDNQEEG--ESEAEGETEAESEFD 164
+ E +++E E E E++ +EEG + + ET+ E E D
Sbjct: 213 EEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 57.8 bits (138), Expect = 1e-08
Identities = 32/100 (32%), Positives = 53/100 (53%)
Query: 86 EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDN 145
E + +S+A + EEE + E E E +E+ ED +EE +E+ +E+ + E + + +E +
Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVS 210
Query: 146 QEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLD 185
+EE E + E E E E + E E KR+ D G D
Sbjct: 211 EEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGED 250
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/90 (36%), Positives = 51/90 (56%), Gaps = 3/90 (3%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESE-DESDEESEEDSEEE 132
+G +E+ E + + E++ EE + E E E +E+ E EE E DE D+E +ED E +
Sbjct: 146 DGYDREDQEAP-DSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDE-DEDVEGD 203
Query: 133 MEDEQESEAEEDNQEEGESEAEGETEAESE 162
+D++ SE EE+ + E E E E E E E
Sbjct: 204 EDDDEVSEEEEEFGLDEEDEDEDEDEEEEE 233
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 96 GEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQE--EGESEA 153
G + E +E +S+ E + +E E++ + E EED ++E +E+E + E+D E EG+ +
Sbjct: 147 GYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD 206
Query: 154 EGETEAESEFDPEIEMEAE 172
+ +E E EF + E E E
Sbjct: 207 DEVSEEEEEFGLDEEDEDE 225
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 65.5 bits (158), Expect = 7e-11
Identities = 81/288 (28%), Positives = 121/288 (42%), Gaps = 35/288 (12%)
Query: 69 PPADG---EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESED--ESDE 123
P A+G E G+ + E + + E E EA ESE E E+E E + E E + E+++
Sbjct: 1854 PEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEK 1913
Query: 124 ESEEDSEE------EMEDEQESE-AEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAK 176
E++ ++E E EDE ESE AE EE EAEG+T+ ESE EAE A+
Sbjct: 1914 EAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIE--SQEAEEEAQ 1971
Query: 177 RKCPD-HGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMI 235
+ D L++ QE + A + + EA EE + + G
Sbjct: 1972 PESEDVEALEVEVETQEAEGEAQPESEDVEAPEAE--GEMQEAEEEAQPESDGVEAQPKS 2029
Query: 236 ELVERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEI 295
E E + + K D Q E V+ A+EE + ++QEA AH
Sbjct: 2030 EGEEAQEVEGETQKTEGD-----AQPESDGVEAPEAEEEAQEAE-GEVQEAEGEAHPESE 2083
Query: 296 LADIQSHMDRLMTQMAQAKEQLDTSNESAE-PKAEGDEEGPSGASEEE 342
D Q +A+ + +E E P+AEG+ + G E
Sbjct: 2084 DVDAQ-----------EAEGEAQPESEGVEAPEAEGEAQKAEGIEAPE 2120
Score = 63.2 bits (152), Expect = 3e-10
Identities = 55/176 (31%), Positives = 84/176 (47%), Gaps = 29/176 (16%)
Query: 15 DGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQA-WTPPADG 73
+G E E + P +E+V EA + + +E V +A W +
Sbjct: 1857 EGDAQEAEGEAQPESEDV-------------EAPEAEGEAQPESEDVETPEAEWEVQPES 1903
Query: 74 EGAGKEEAE------------VKVEQEREIESEAGEESESEEESESEEESETEEESEDES 121
EGA EAE ++ E E E ESE E E+EE ++ E E +T+ ESE
Sbjct: 1904 EGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQ-EAEGQTQPESEVIE 1962
Query: 122 DEESEEDSEEEMEDEQESEAEEDNQE-EGESEAEGETEAESEFDPEIEMEAERVAK 176
+E+EE+++ E ED + E E + QE EGE++ E E E + E++ EAE A+
Sbjct: 1963 SQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ-EAEEEAQ 2017
Score = 62.4 bits (150), Expect = 6e-10
Identities = 57/164 (34%), Positives = 74/164 (45%), Gaps = 19/164 (11%)
Query: 20 ECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKE 79
E + EAP AEE +E EAH + +E V +A A E G E
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPE-------SEDVDAQEA-EGEAQPESEGVE 2102
Query: 80 EAEVKVEQER-------EIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEE 132
E + E ++ E E EA ESE E E+E E++ E E + D E E E E
Sbjct: 2103 APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESE 2162
Query: 133 MEDEQESEAEEDNQEEG--ESEAEGETEAESE--FDPEIEMEAE 172
+ QE+E E + EG EAEGE + ESE PE E EA+
Sbjct: 2163 GIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQ 2206
Score = 58.5 bits (140), Expect = 8e-09
Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 5/115 (4%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
A E G E E + E + E+E E+E E + ESE E E E + + E E E
Sbjct: 2157 AQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPE 2216
Query: 131 EEMEDEQESEAEEDNQEEGES--EAEGETEAESEFDPEIEM---EAERVAKRKCP 180
E E + E E E + EGE+ E+EGET+ E + P++ + ++E ++ P
Sbjct: 2217 AEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSP 2271
Score = 57.0 bits (136), Expect = 2e-08
Identities = 62/176 (35%), Positives = 76/176 (43%), Gaps = 39/176 (22%)
Query: 20 ECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKE 79
E E EA AEE +E AE Q V SQ A E E
Sbjct: 1934 ESEGAEAQEAEEAAQE---------AEGQTQP------ESEVIESQEAEEEAQPESEDVE 1978
Query: 80 EAEVKVEQEREIESEAGEESESEEESESEEE-SETEEESEDESD---------------- 122
EV+VE + E E EA ESE E E+E E E EEE++ ESD
Sbjct: 1979 ALEVEVETQ-EAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEV 2037
Query: 123 ----EESEEDSEEEMEDEQESEAEEDNQE-EGE-SEAEGETEAESEFDPEIEMEAE 172
+++E D++ E + + EAEE+ QE EGE EAEGE ESE E E E
Sbjct: 2038 EGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGE 2093
Score = 57.0 bits (136), Expect = 2e-08
Identities = 39/112 (34%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 69 PPADGEGAGKEEAEVKVEQE----REIESEAGEESESEEESESEEESETE----EESEDE 120
P ++G A + E E + E E ++ E EA ESE E E+EEE++ E E E E
Sbjct: 2127 PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAE 2186
Query: 121 SDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
+ + E + E E E E++ E + E E+E E + E E PE E EA+
Sbjct: 2187 GEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQ 2238
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/106 (36%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Query: 69 PPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDE--ESE 126
P ++G A E E + E E EA EE++ E E E+E E + E E E E+E
Sbjct: 2143 PESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAE 2202
Query: 127 EDSEEEMEDEQESEAEEDNQEEGES----EAEGETEAESEFDPEIE 168
+++ E+E + EAEE+ Q E E EAEGE + ESE + + E
Sbjct: 2203 GEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGE 2248
Score = 56.2 bits (134), Expect = 4e-08
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 6/107 (5%)
Query: 70 PADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDS 129
P +GA EA + E E + ESE E E+E +++ E E E + ESED E+E ++
Sbjct: 1826 PGQSDGAEGIEAP-EAEGEAQPESEGVEAPEAEGDAQ-EAEGEAQPESEDVEAPEAEGEA 1883
Query: 130 EEEMEDEQESEAEEDNQEEGES----EAEGETEAESEFDPEIEMEAE 172
+ E ED + EAE + Q E E EAE E + E+E +E E E
Sbjct: 1884 QPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGE 1930
Score = 55.1 bits (131), Expect = 9e-08
Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 20/120 (16%)
Query: 69 PPADGEGAGKEEAEV-KVEQEREIESEAGEESESEEESESEE------ESETEEESEDES 121
P ++GE A + E E K E + + ES+ E E+EEE++ E E E ESED
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD 2086
Query: 122 DEESEEDSEEEMEDEQESEAEEDNQE-------EGESEAEGET------EAESEFDPEIE 168
+E+E +++ E E + EAE + Q+ E E EA+ E+ EAE E PE E
Sbjct: 2087 AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146
Score = 53.1 bits (126), Expect = 3e-07
Identities = 42/112 (37%), Positives = 57/112 (50%), Gaps = 11/112 (9%)
Query: 69 PPADG-EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDE--ES 125
P +DG E K E E E E E + G+ ++ ES+ E E EEE+++ E E+
Sbjct: 2018 PESDGVEAQPKSEGEEAQEVEGETQKTEGD---AQPESDGVEAPEAEEEAQEAEGEVQEA 2074
Query: 126 EEDSEEEMEDEQESEAEEDNQEEGES----EAEGETE-AESEFDPEIEMEAE 172
E ++ E ED EAE + Q E E EAEGE + AE PE E EA+
Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQ 2126
Score = 53.1 bits (126), Expect = 3e-07
Identities = 44/128 (34%), Positives = 61/128 (47%), Gaps = 16/128 (12%)
Query: 69 PPADGEGAGKEEAEVKVEQEREIESEAGE-ESESEEESESEEESETEEESEDESDEESE- 126
P +DG A + E E + E E E++ GE ESE+ E E E + ESE E+E
Sbjct: 2050 PESDGVEAPEAEEEAQ-EAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEG 2108
Query: 127 --------EDSEEEMEDEQESEAEEDNQEEGESEAEGE----TEAESEFDPEIE-MEAER 173
E E E E + ESE E + EGE++ E E +AE E PE E +EA+
Sbjct: 2109 EAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQE 2168
Query: 174 VAKRKCPD 181
+ P+
Sbjct: 2169 AEEEAQPE 2176
Score = 52.8 bits (125), Expect = 5e-07
Identities = 37/102 (36%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
A E G E E + E + E E +++E E + ESE E E E + + E E E
Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGE----TEAESEFDPEIE 168
E E + ESE E + EGE++ E E EAE E PE E
Sbjct: 2185 AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPE 2226
Score = 48.1 bits (113), Expect = 1e-05
Identities = 40/113 (35%), Positives = 60/113 (53%), Gaps = 14/113 (12%)
Query: 73 GEGAGKE-----EAEVKVEQEREIESEAGEESESEE-ESESEEESETEEESEDESD-EES 125
G+G+G E EA +Q+ +S+ E E+ E E E++ ESE E E E D +E+
Sbjct: 1805 GQGSGHEDNLQGEAAAGGDQDPG-QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEA 1863
Query: 126 EEDSEEEMEDEQESEAEEDNQEEGE------SEAEGETEAESEFDPEIEMEAE 172
E +++ E ED + EAE + Q E E +E E + E+E PE E EA+
Sbjct: 1864 EGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQ 1916
Score = 47.0 bits (110), Expect = 2e-05
Identities = 68/265 (25%), Positives = 114/265 (43%), Gaps = 22/265 (8%)
Query: 76 AGKEEAEVKVEQEREIESEAGEE----SESEEESESEEESETEEESEDESDEESEEDSEE 131
AG E E EQE E SE GE S E+ + E + +++ E E E
Sbjct: 1783 AGSELGEA--EQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEA 1840
Query: 132 EMEDEQESEAEEDNQEEGES-EAEGETEAESE--FDPEIEMEAERVAKRKCPDHGLDLST 188
E E + ESE E + EG++ EAEGE + ESE PE E EA+ ++ D+ T
Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESE--------DVET 1892
Query: 189 -YCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSD 247
+ + Q A + Q T E+ E L ++ ++ E E +
Sbjct: 1893 PEAEWEVQPESEGAEAPEAEKEAQPET--ESVEALETEGEDEPESEGAEAQEAEEAAQEA 1950
Query: 248 PKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLM 307
T+ + ++ QE ++ + +++ + V+ QEA A D+++
Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPES--EDVEAPEAEGE 2008
Query: 308 TQMAQAKEQLDTSNESAEPKAEGDE 332
Q A+ + Q ++ A+PK+EG+E
Sbjct: 2009 MQEAEEEAQPESDGVEAQPKSEGEE 2033
Score = 42.4 bits (98), Expect = 6e-04
Identities = 47/179 (26%), Positives = 69/179 (38%), Gaps = 28/179 (15%)
Query: 25 EAPGAEEVCRECGF--------CYC-------RRHAEAHRQKFLSHHLAEYV--HGSQAW 67
E+PG E ++C F C C R +E R LAE Q
Sbjct: 1245 ESPGDLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLE 1304
Query: 68 TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEE 127
EG G +E V++E+ + EE EE + EE ETE E + E + + EE
Sbjct: 1305 ETKEGTEGEGLQEEAVQLEETKT------EEGLQEEGVQLEETKETEGEGQQEEEAQLEE 1358
Query: 128 DSEEEMEDEQESEAEEDNQEEG-----ESEAEGETEAESEFDPEIEMEAERVAKRKCPD 181
E E QE + + +EG + EA E E E + + +++ PD
Sbjct: 1359 IEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPD 1417
Score = 40.0 bits (92), Expect = 0.003
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 69 PPADGEGAGKEEAEVKVEQEREIESEAGEESESEEE--SESEEESETEEESEDESDEESE 126
P ++G A + E E + E E EA EE++ E E E E E + ESE E+ E +
Sbjct: 2191 PESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250
Query: 127 EDSEEEMEDEQESEAEEDN 145
+ + D Q EA E +
Sbjct: 2251 GSPQVSLGDGQSEEASESS 2269
Score = 38.5 bits (88), Expect = 0.009
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
Query: 69 PPADGEGAGKEEAEVKVEQER----EIESEAGEESESEE--ESESEEESETEEESEDESD 122
P +G A + E E + E E E E EA E E E E+E E + E E E++
Sbjct: 2175 PELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAE 2234
Query: 123 EESEEDSEEEMEDEQESEAE---EDNQEEGESEAEGETEAESEFDP 165
E++ +SE E + E++ + D Q E SE+ + P
Sbjct: 2235 GEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPP 2280
Score = 37.0 bits (84), Expect = 0.026
Identities = 39/123 (31%), Positives = 53/123 (43%), Gaps = 14/123 (11%)
Query: 68 TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEE 127
T +GEG +EEA+++ EIE E G E EE + EE E E E EE
Sbjct: 1341 TKETEGEGQQEEEAQLE-----EIE-ETGGEGLQEEGVQLEEVKEGPEGG--LQGEALEE 1392
Query: 128 DSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER--VAKRKCPDHGLD 185
+EE E+ S ++ E + +G E DP E EA R + CP G +
Sbjct: 1393 GLKEEGLPEEGSVHGQELSEASSPDGKG----SQEDDPVQEEEAGRASASAEPCPAEGTE 1448
Query: 186 LST 188
T
Sbjct: 1449 EPT 1451
Score = 36.2 bits (82), Expect = 0.044
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 8/99 (8%)
Query: 75 GAGKEEAEVKVEQERE-----IESEAGEESESEE---ESESEEESETEEESEDESDEESE 126
G G +E V++E+ +E ++ EA EE EE E S E E S + E
Sbjct: 1364 GEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQE 1423
Query: 127 EDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDP 165
+D +E E + S + E EG E SE DP
Sbjct: 1424 DDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDP 1462
Score = 33.5 bits (75), Expect = 0.28
Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 19/170 (11%)
Query: 68 TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESE----EESETEEESEDESDE 123
TP A+GE + E E + E++ + G + +SEE SES E+ T S
Sbjct: 2230 TPEAEGEAQPESEGETQGEKKGSPQVSLG-DGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288
Query: 124 ESEEDSEEEMEDEQESEAEEDNQEEGESE-AEGET---EAESEFDPEIEMEAERVAKRKC 179
S+ + S Q++ E++ G+T +A+S P AER A R
Sbjct: 2289 HQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTP----HAERKATRMY 2344
Query: 180 PDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGG 229
P+ S+ +++ + P GA +G+ L D+A L ++ G
Sbjct: 2345 PE-----SSTSEQEEAPLGSRTPEQGASEGYDLQE-DQALGSLAPTEAVG 2388
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 65.5 bits (158), Expect = 7e-11
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 72 DGEGAGKEEAEVKVEQER-EIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
D E +E KVE + IE + E E EEE E EE+ E+EEE E+E + E E E
Sbjct: 505 DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDE 564
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYC 190
E+ + E ++ + ++ E ++E +S+ D E A AKR+ L+ S
Sbjct: 565 EDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNV 624
Query: 191 QEDRQLICVLCPVIGAHQGHQLSTLDE-AFEELRSKDSGGL 230
++ ++C V+G + LD+ ++ ++GG+
Sbjct: 625 NTEKLRAPIIC-VLGHVDTGKTKILDKLRHTHVQDGEAGGI 664
Score = 52.4 bits (124), Expect = 6e-07
Identities = 63/286 (22%), Positives = 128/286 (44%), Gaps = 31/286 (10%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
A +E+AE E + E + ++ + +++ E EE+ + +++ ++ ++ +++ ++++
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE 353
Query: 136 EQESEAEEDNQ-----EEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYC 190
E+E + E+ + EE E++ + E E E E + + E+ K + G L+
Sbjct: 354 EEERQKREEEERIKRLEELEAKRKEEERLEQE-KRERKKQKEKERKERLKKEGKLLTKSQ 412
Query: 191 QEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKF------- 243
+E R A L L E+ SKDS K + E +R K
Sbjct: 413 REAR-----------ARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESK 461
Query: 244 ---KSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHL-VDIQEAMATAHVTEILADI 299
+S + + M+ + ++ + V +EE+ +D EAMA+ TE +
Sbjct: 462 EVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGN 521
Query: 300 QSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASE--EED 343
+ H++ + + +E+ + E E + E +EEG S SE EED
Sbjct: 522 KVHIE-VKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 10/105 (9%)
Query: 91 IESEAGEESESEEESESEEESETEEESEDE-----SDEESEEDSEEEMEDEQESEAEEDN 145
+E E+ E+ E EEE +TE+ D+ SDEE+E+ ++ E + EE+
Sbjct: 476 MEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEE 535
Query: 146 QEEGESEAEGETEAESEFDPEIE-----MEAERVAKRKCPDHGLD 185
+EE E E + E+E E E + E E E E+V+ K LD
Sbjct: 536 EEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLD 580
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 28/182 (15%)
Query: 19 DECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGK 78
+E P P EE + G + S E V G++ + +
Sbjct: 484 EETPPPVEPEEEEDTEDAGL--------DDWEAMASDEETEKVEGNKVHIEVKENPEEEE 535
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138
EE E + E E ESEEE E E ESE E E++ E+DS + ++ +
Sbjct: 536 EEEEEEEEDE-----------ESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Query: 139 SEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLIC 198
E D++ + + + T+ E +D +A+R +++ +H +++T + +IC
Sbjct: 585 KEMSSDSEYDSDDD---RTKEERAYD-----KAKRRIEKRRLEHSKNVNTE-KLRAPIIC 635
Query: 199 VL 200
VL
Sbjct: 636 VL 637
Score = 42.7 bits (99), Expect = 5e-04
Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 31/110 (28%)
Query: 86 EQEREIESEAGEESESEEESESEEESETEEESEDE--------------SDEES------ 125
E +E A E + E EE E E+E SDEE+
Sbjct: 462 EVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGN 521
Query: 126 ----------EEDSEEEMEDEQESEAEEDNQEEGESE-AEGETEAESEFD 164
EE+ EEE E+E++ E+EE+ +EEGESE +EG+ E E D
Sbjct: 522 KVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSD 571
Score = 36.2 bits (82), Expect = 0.044
Identities = 23/95 (24%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 85 VEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ-ESEAEE 143
V Q++ + E + EE+++ + E EE + D+ +++S+ + E+E +S+
Sbjct: 228 VAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTV 287
Query: 144 DNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
D SE + ET +E D E + + + K+K
Sbjct: 288 DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKK 322
Score = 32.0 bits (71), Expect = 0.83
Identities = 26/119 (21%), Positives = 55/119 (46%), Gaps = 9/119 (7%)
Query: 57 LAEYVHGSQAWTPPADGEGAGKEEAEVKVEQ--EREIESEAGEESESEEESESEEESETE 114
LA + G+ A + GK++ E K + E +I E E S + +++ E+
Sbjct: 22 LAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAV 81
Query: 115 EESEDESDEESEEDSEEEME-------DEQESEAEEDNQEEGESEAEGETEAESEFDPE 166
+ +E+ +E + +D +++ + D+ +SE ED + + A+ + E S D +
Sbjct: 82 KPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDD 140
Score = 30.4 bits (67), Expect = 2.4
Identities = 44/228 (19%), Positives = 92/228 (40%), Gaps = 38/228 (16%)
Query: 79 EEAEVKVEQEREIES--EAGEESESEEESESEEESETEE------ESEDESDEES----- 125
E+ K+++ I S E+G+ES+ +S ++ + ES +E D+ S
Sbjct: 168 EDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKT 227
Query: 126 -----EEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP 180
E E E + E +A+ +E E G+ + + + + + E E V +
Sbjct: 228 VAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTV 287
Query: 181 DHGL--------DLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKA 232
D G+ + T ++D + + + E E+ + K G KA
Sbjct: 288 DTGVIPASEEKAETPTAAEDDNE--------GDKKKKDKKKKKGEKEEKEKEKKKGPSKA 339
Query: 233 AMIELVERL-KFKSSDPKVTRDQ---MKMFIQQEFKKVQKVIADEEQK 276
+ + E L K K + + R++ +K + E K+ ++ ++E++
Sbjct: 340 TVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKR 387
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 65.1 bits (157), Expect = 9e-11
Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133
E EE E + E+E E E EE E +E E EE + E+E E++ ++ E+ EE
Sbjct: 2241 ESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ 2300
Query: 134 EDEQESEAEED--NQEEGESEAEGETEAES-EFDPEIEMEAERVAKRK 178
E E+ E +E+ ++EE ES ++ E E ES + E++ E E + K K
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Score = 59.7 bits (143), Expect = 4e-09
Identities = 31/93 (33%), Positives = 51/93 (54%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138
EE E +++ + ES + EE E EE E EE E EE E+ +EE E+ + E E+E++
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Query: 139 SEAEEDNQEEGESEAEGETEAESEFDPEIEMEA 171
+ +++ ++E E E E + E E E E+
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEETES 2320
Score = 57.4 bits (137), Expect = 2e-08
Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 7/95 (7%)
Query: 84 KVEQEREIESEAGEESESEEESESEEESETEEE--SEDESDEESEEDSEEEMEDEQESEA 141
++E++ + SE EE E EEE E EE E EEE E+E +E+ E EEE + +++ +
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 142 EEDNQE-----EGESEAEGETEAESEFDPEIEMEA 171
+E+ QE E + E E E ES D E E E+
Sbjct: 2296 KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEES 2330
Score = 55.8 bits (133), Expect = 5e-08
Identities = 66/275 (24%), Positives = 119/275 (43%), Gaps = 30/275 (10%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEES-ETEEESEDESDEESEEDSEEEME 134
A KEE E ++ QE E +AGE+ EEE E++ + EE + + S + E++ +
Sbjct: 1480 AWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYK 1539
Query: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPE-----IEMEAERVAKRKCPDH---GLDL 186
DE+E EE+ EGE + + TE + E I + R K++ + +
Sbjct: 1540 DEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE 1599
Query: 187 STYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSS 246
QE+RQL + L +A+ ++ D +A +
Sbjct: 1600 EKLAQEERQL------------AQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQR 1647
Query: 247 DPKVTRDQMKMFIQQE--FKKVQKVIADEE---QKALHLVDIQEAMATAHVTEILADIQS 301
K++++ K+ +++ KK +KV +EE +K L +++ + A E L +
Sbjct: 1648 GEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNIL--AQKVEELPQREQ 1705
Query: 302 HMDRLMTQMAQAKEQLDTSNESAEPKAE--GDEEG 334
++D ++AQ E+L+ E K E EEG
Sbjct: 1706 NLDWQEKELAQELEELEWDMEELSWKEEELNQEEG 1740
Score = 54.7 bits (130), Expect = 1e-07
Identities = 31/95 (32%), Positives = 47/95 (49%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+ E E E ++ +ES S EE E EE E EE E +EE ++ EE E +
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
E E EE +++ E + E E E F+ + E+ +E
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315
Score = 53.9 bits (128), Expect = 2e-07
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 77 GKEEAEVKVEQEREIESEA--GEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G + E Q E+ESE EE ES + ++ES + EE E+ +EE E+ E E
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Query: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
+E+ E EE +++ E E E + + + E E E E V + K
Sbjct: 2266 EEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK 2309
Score = 50.8 bits (120), Expect = 2e-06
Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K + + ++ +E S +E ESEE E ES +E + ES EE+ EE E+ +
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
E E E+ +E E E E + E E E E + ++ K+K
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKE---EEEKKKKKKEKKK 2296
Score = 47.8 bits (112), Expect = 1e-05
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 72 DGEGAGKEEAEV----KVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEE 127
D E G EE EV K + E++ G++ + + S+ +E E SE+ E
Sbjct: 2178 DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDEL 2237
Query: 128 DSEEEMEDEQESEAEE-DNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
+ +E + E+E E EE + +EE E E E E E E ++E E K+K
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKK 2289
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/74 (33%), Positives = 44/74 (59%), Gaps = 4/74 (5%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESET---EEESEDESDEESEEDSEEE-M 133
+E+ + K E+++E E E E +EE SEEE+E+ EEE E+ E E D E+E +
Sbjct: 2285 EEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL 2344
Query: 134 EDEQESEAEEDNQE 147
+ E++ + +E ++
Sbjct: 2345 KKEKQFKLQEQRRK 2358
Score = 38.1 bits (87), Expect = 0.012
Identities = 57/277 (20%), Positives = 115/277 (41%), Gaps = 46/277 (16%)
Query: 77 GKEEAEVKVEQEREIESEAGEES--ESEEESESEEESETEEESEDESDEESEEDSEE-EM 133
G + AEVK +++E E + +E+ ++E E E + E+ S +E E + EE ++
Sbjct: 1683 GGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKL 1742
Query: 134 EDEQESEAEEDN----QEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTY 189
+E++ AEE+ Q E SE E + E E + E E++A+ K
Sbjct: 1743 VEEKKKLAEEEEALAWQREKLSEEETKLAQEEEL---LIQEKEKLAQHK----------- 1788
Query: 190 CQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPK 249
+ E E L K ++ M +R ++ +S +
Sbjct: 1789 -----------------------EKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEE 1825
Query: 250 VTRDQMKMFIQQEFKKVQKVIADEEQKALHLVD--IQEAMATAHVTEILADIQSHMDRLM 307
+T+++M ++ ++ + +K +A E++K + + H + L +++ +
Sbjct: 1826 LTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFN 1885
Query: 308 TQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT 344
+AQ +E+L E+ K E E + ED+
Sbjct: 1886 KILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDS 1922
Score = 32.7 bits (73), Expect = 0.49
Identities = 30/127 (23%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 47 AHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESE 106
A +Q+ L++ + ++ + T E + E+E IE E +
Sbjct: 2140 ARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRK 2199
Query: 107 SEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPE 166
+E ++ E S + E +SEE +E ES +E ++E S E E E
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEE---------E 2250
Query: 167 IEMEAER 173
E E ER
Sbjct: 2251 REEEEER 2257
Score = 28.9 bits (63), Expect = 7.0
Identities = 22/96 (22%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 84 KVEQEREIESEAGEESESEEESE-SEEESETEEESEDESDEESEEDSEEEMEDEQESEAE 142
K+ +I ++ E+ E+E+ ++E E E + E+S +E++ E+ A
Sbjct: 1880 KLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLAL 1939
Query: 143 EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
E +G+ GE + E + + +E +R+A+ K
Sbjct: 1940 EKAMVQGKKRLRGELDIAKE-EKALNLEMKRLAEEK 1974
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 64.3 bits (155), Expect = 2e-10
Identities = 34/93 (36%), Positives = 57/93 (61%), Gaps = 8/93 (8%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESE---- 126
A +G KEE + + E E++ E+E GEE E +EE + +E+ E +++ ++ S+EE E
Sbjct: 180 AQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD 239
Query: 127 --EDSEEEMEDEQESEA--EEDNQEEGESEAEG 155
ED E+E EDE+E E+ E+ + E + E +G
Sbjct: 240 KDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272
Score = 57.4 bits (137), Expect = 2e-08
Identities = 30/89 (33%), Positives = 53/89 (59%), Gaps = 2/89 (2%)
Query: 72 DGEGAGKEEAEVKVEQ-EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
D E +++ +V+ ++E E E GE+ E + E+E EE E +EE +++ D E ++D +
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGED-EKDXENEDGEEEELDEEEDEDEDVEGDDDKD 227
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGETEA 159
E E+E+E ++D +E E E E E E+
Sbjct: 228 EVSEEEEEFGLDKDEDDEDEDEDEEEEES 256
Score = 54.7 bits (130), Expect = 1e-07
Identities = 27/80 (33%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 88 EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEE---- 143
+ + + + ++ E +EE E E++ E E+ E+E DEE +ED + E +D+++ +EE
Sbjct: 177 DSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEF 236
Query: 144 --DNQEEGESEAEGETEAES 161
D E+ E E E E E ES
Sbjct: 237 GLDKDEDDEDEDEDEEEEES 256
Score = 52.4 bits (124), Expect = 6e-07
Identities = 27/93 (29%), Positives = 52/93 (55%)
Query: 86 EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDN 145
E + +S+A + +EE + E E E + E+ED +EE +E+ +E+ + E + + +E +
Sbjct: 171 EDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVS 230
Query: 146 QEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
+EE E + + + E E + E E E+ + RK
Sbjct: 231 EEEEEFGLDKDEDDEDEDEDEEEEESGKGENRK 263
Score = 51.2 bits (121), Expect = 1e-06
Identities = 24/72 (33%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Query: 92 ESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGES 151
+ E E +S+ + + ++ E +EE EDE D E+E+ EEE+++E+ +ED EG+
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEE----DEDEDVEGDD 224
Query: 152 EAEGETEAESEF 163
+ + +E E EF
Sbjct: 225 DKDEVSEEEEEF 236
Score = 35.4 bits (80), Expect = 0.075
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 108 EEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
+ E + +S+ + D +E+ +EE EDE++ E ED +EE E E E E D +
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXE-NEDGEEEELDEEEDEDEDVEGDDDKD 227
Query: 168 EMEAE 172
E+ E
Sbjct: 228 EVSEE 232
Score = 31.2 bits (69), Expect = 1.4
Identities = 15/48 (31%), Positives = 23/48 (47%)
Query: 119 DESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPE 166
D D E +E + + + + + EED + E E + E E E E D E
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEE 213
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 64.3 bits (155), Expect = 2e-10
Identities = 34/93 (36%), Positives = 57/93 (61%), Gaps = 8/93 (8%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESE---- 126
A +G KEE + + E E++ E+E GEE E +EE + +E+ E +++ ++ S+EE E
Sbjct: 180 AQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD 239
Query: 127 --EDSEEEMEDEQESEA--EEDNQEEGESEAEG 155
ED E+E EDE+E E+ E+ + E + E +G
Sbjct: 240 KDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272
Score = 57.4 bits (137), Expect = 2e-08
Identities = 30/89 (33%), Positives = 53/89 (59%), Gaps = 2/89 (2%)
Query: 72 DGEGAGKEEAEVKVEQ-EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130
D E +++ +V+ ++E E E GE+ E + E+E EE E +EE +++ D E ++D +
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGED-EKDXENEDGEEEELDEEEDEDEDVEGDDDKD 227
Query: 131 EEMEDEQESEAEEDNQEEGESEAEGETEA 159
E E+E+E ++D +E E E E E E+
Sbjct: 228 EVSEEEEEFGLDKDEDDEDEDEDEEEEES 256
Score = 54.7 bits (130), Expect = 1e-07
Identities = 27/80 (33%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 88 EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEE---- 143
+ + + + ++ E +EE E E++ E E+ E+E DEE +ED + E +D+++ +EE
Sbjct: 177 DSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEF 236
Query: 144 --DNQEEGESEAEGETEAES 161
D E+ E E E E E ES
Sbjct: 237 GLDKDEDDEDEDEDEEEEES 256
Score = 52.4 bits (124), Expect = 6e-07
Identities = 27/93 (29%), Positives = 52/93 (55%)
Query: 86 EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDN 145
E + +S+A + +EE + E E E + E+ED +EE +E+ +E+ + E + + +E +
Sbjct: 171 EDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVS 230
Query: 146 QEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
+EE E + + + E E + E E E+ + RK
Sbjct: 231 EEEEEFGLDKDEDDEDEDEDEEEEESGKGENRK 263
Score = 51.2 bits (121), Expect = 1e-06
Identities = 24/72 (33%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Query: 92 ESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGES 151
+ E E +S+ + + ++ E +EE EDE D E+E+ EEE+++E+ +ED EG+
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEE----DEDEDVEGDD 224
Query: 152 EAEGETEAESEF 163
+ + +E E EF
Sbjct: 225 DKDEVSEEEEEF 236
Score = 35.4 bits (80), Expect = 0.075
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 108 EEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
+ E + +S+ + D +E+ +EE EDE++ E ED +EE E E E E D +
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXE-NEDGEEEELDEEEDEDEDVEGDDDKD 227
Query: 168 EMEAE 172
E+ E
Sbjct: 228 EVSEE 232
Score = 31.2 bits (69), Expect = 1.4
Identities = 15/48 (31%), Positives = 23/48 (47%)
Query: 119 DESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPE 166
D D E +E + + + + + EED + E E + E E E E D E
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEE 213
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 64.3 bits (155), Expect = 2e-10
Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 3/141 (2%)
Query: 38 FCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGE 97
+ YC+R AE E + + +G E + E++ + E E E
Sbjct: 967 YSYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKE--E 1024
Query: 98 ESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGET 157
E E +E E +EE E E+ DE +EE EE+ EEE +E E+E EE E + E+
Sbjct: 1025 EEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAES 1084
Query: 158 EAESEFDPEIEMEAERVAKRK 178
+A S ++ +E+V++ K
Sbjct: 1085 QA-SSLGQKVGESSEQVSEEK 1104
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/166 (24%), Positives = 65/166 (39%), Gaps = 21/166 (12%)
Query: 35 ECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESE 94
ECG C + A H+ HHL E++ + P + GK + +
Sbjct: 917 ECGIC---KKAFKHK-----HHLIEHMR-LHSGEKPYQCDKCGKRFSHSGSYSQHMNHRY 967
Query: 95 AGEESESEEESESEEESETEE------------ESEDESDEESEEDSEEEMEDEQESEAE 142
+ + E+EE +E+E E S+ +SDE EE+ + E+E E E
Sbjct: 968 SYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEE 1027
Query: 143 EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLST 188
+ EE + E E E E + E E E E + + G + T
Sbjct: 1028 DKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKT 1073
Score = 37.7 bits (86), Expect = 0.015
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 10/77 (12%)
Query: 92 ESEAGEESES--EEESESEEESETEEESEDESDEESEEDSE---EEMEDEQES-----EA 141
E + G+E + E++++E T ++ E ESD E+E++ + EE +Q++ EA
Sbjct: 67 EDDTGKEGQEILGPEAQADEAGCTVKDDECESDAENEQNHDPNVEEFLQQQDTAVIFPEA 126
Query: 142 EEDNQEEGESEAEGETE 158
E++Q +G EA G E
Sbjct: 127 PEEDQRQGTPEASGHDE 143
Score = 32.7 bits (73), Expect = 0.49
Identities = 21/94 (22%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEES--EEDSEEEMED- 135
+E ++ + +E + A E E++ +++ SE E + ++ E+D+ +E ++
Sbjct: 18 DEDKLHIVEEESVTDAADCEGVPEDDLPTDQTVLPGRSSEREGNAKNCWEDDTGKEGQEI 77
Query: 136 -EQESEAEEDNQEEGESEAEGETEAESEFDPEIE 168
E++A+E + E E + E E DP +E
Sbjct: 78 LGPEAQADEAGCTVKDDECESDAENEQNHDPNVE 111
Score = 29.3 bits (64), Expect = 5.4
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 96 GEESESEEESESEEESETEEESEDESDEESEEDSE--EEMEDEQESEAEEDNQEEGESEA 153
G SE E +++ E +T +E ++ E++ D +DE ES+AE + + E
Sbjct: 53 GRSSEREGNAKNCWEDDTGKEGQEILGPEAQADEAGCTVKDDECESDAENEQNHDPNVEE 112
Query: 154 EGETEAESEFDPEIEMEAERVAKRKCPDH 182
+ + + PE E +R + H
Sbjct: 113 FLQQQDTAVIFPEAPEEDQRQGTPEASGH 141
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 64.3 bits (155), Expect = 2e-10
Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 3/141 (2%)
Query: 38 FCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGE 97
+ YC+R AE E + + +G E + E++ + E E E
Sbjct: 983 YSYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKE--E 1040
Query: 98 ESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGET 157
E E +E E +EE E E+ DE +EE EE+ EEE +E E+E EE E + E+
Sbjct: 1041 EEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAES 1100
Query: 158 EAESEFDPEIEMEAERVAKRK 178
+A S ++ +E+V++ K
Sbjct: 1101 QA-SSLGQKVGESSEQVSEEK 1120
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/166 (24%), Positives = 65/166 (39%), Gaps = 21/166 (12%)
Query: 35 ECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESE 94
ECG C + A H+ HHL E++ + P + GK + +
Sbjct: 933 ECGIC---KKAFKHK-----HHLIEHMR-LHSGEKPYQCDKCGKRFSHSGSYSQHMNHRY 983
Query: 95 AGEESESEEESESEEESETEE------------ESEDESDEESEEDSEEEMEDEQESEAE 142
+ + E+EE +E+E E S+ +SDE EE+ + E+E E E
Sbjct: 984 SYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEE 1043
Query: 143 EDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLST 188
+ EE + E E E E + E E E E + + G + T
Sbjct: 1044 DKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKT 1089
Score = 33.5 bits (75), Expect = 0.28
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 21/112 (18%)
Query: 68 TPPADGEGAGKEE--AEVKVEQEREIESEAGEESESEEESESEEESETEEESEDES---- 121
T AD EG +++ + V R E E ++ E++ + +E E DE+
Sbjct: 48 TDAADCEGVPEDDLPTDQTVLPGRSSEREGNAKNCWEDDRKEGQEILGPEAQADEAGCTV 107
Query: 122 -DEESEEDSE---------EEMEDEQES-----EAEEDNQEEGESEAEGETE 158
D+E E D+E EE +Q++ EA E++Q +G EA G E
Sbjct: 108 KDDECESDAENEQNHDPNVEEFLQQQDTAVIFPEAPEEDQRQGTPEASGHDE 159
Score = 32.7 bits (73), Expect = 0.49
Identities = 22/93 (23%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEES--EEDSEEEMED- 135
+E ++ + +E + A E E++ +++ SE E + ++ E+D +E E
Sbjct: 35 DEDKLHIVEEESVTDAADCEGVPEDDLPTDQTVLPGRSSEREGNAKNCWEDDRKEGQEIL 94
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIE 168
E++A+E + E E + E E DP +E
Sbjct: 95 GPEAQADEAGCTVKDDECESDAENEQNHDPNVE 127
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 64.3 bits (155), Expect = 2e-10
Identities = 40/118 (33%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE- 136
+ E + + E+ERE+E E E E E E E + E + + + + E + E E D E+E E E
Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753
Query: 137 QESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDR 194
+E E E + + E E E E E E E D E E + + K K D + +EDR
Sbjct: 754 EERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDR 811
Score = 61.2 bits (147), Expect = 1e-09
Identities = 39/109 (35%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+ E E + ++ERE E E E E E E E+E + E + + + D E E + E + E E+
Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKER 749
Query: 138 ESEAEE-DNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLD 185
E E EE + + E E E E E E E E E + E ER + D G D
Sbjct: 750 EREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRD 798
Score = 56.6 bits (135), Expect = 3e-08
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIE------SEA 95
RRH E R+ + Q + P +G E + +ER ++ E
Sbjct: 624 RRHGERDRR--------DNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDER 675
Query: 96 GEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEG 155
E + E E + E E E E E + E ++E E + E E E+E E E D + + + + +
Sbjct: 676 ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR 735
Query: 156 ETEAESEFDPEIEMEAERVAKRK 178
E E E E D E E E ER + +
Sbjct: 736 ERERERERDREKEREREREERER 758
Score = 48.5 bits (114), Expect = 9e-06
Identities = 46/200 (23%), Positives = 87/200 (43%), Gaps = 29/200 (14%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+E E + E+ERE E E E E E E E ++E E + D E ++ ++ +++
Sbjct: 751 REREERERERERE------RERERERERERERARERDKERERQRDWEDKDKGRDDRREKR 804
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLI 197
E E+ N +G E + + +E P + R + ++ +H D Y D +
Sbjct: 805 EEIREDRNPRDGHDERKSKKRYRNEGSP-----SPRQSPKRRREHSPDSDAYNSGDDK-- 857
Query: 198 CVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTR-DQMK 256
++ H+L + + +R ++S L + + + ++K D K R + +
Sbjct: 858 ---------NEKHRLLS-----QVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSR 903
Query: 257 MFIQQEFK-KVQKVIADEEQ 275
+ +QE K KV V EQ
Sbjct: 904 RYEEQELKEKVSSVDKQREQ 923
Score = 32.7 bits (73), Expect = 0.49
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 97 EESESEEESESEEESETEEESED-ESDEESEEDSEEEMEDEQESEAEEDNQEEGE 150
E+ + E S+ E ED + E+DS EE E EQ+ + D++++ E
Sbjct: 397 EKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 451
Score = 32.7 bits (73), Expect = 0.49
Identities = 34/163 (20%), Positives = 68/163 (41%), Gaps = 22/163 (13%)
Query: 86 EQEREIESEAGE---ESESEEESESEEESETEEESEDESDEESEEDSEEEMED------- 135
E +R++ S +G +E E + E E E D E + D++++
Sbjct: 1281 ESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRL 1340
Query: 136 -EQESEAEEDNQEEGESEAE----GETEAESEFDPEIEMEAERV-AKRKCP-----DHGL 184
E+E E E D + + + E E E + + D + E+ ++ + ++C +H
Sbjct: 1341 RERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHER 1400
Query: 185 DLSTYCQEDRQLICV-LCPVIGAHQGHQLSTLDEAFEELRSKD 226
DL + ++ L + +G+ QG + + E E L + D
Sbjct: 1401 DLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGD 1443
Score = 31.2 bits (69), Expect = 1.4
Identities = 40/224 (17%), Positives = 88/224 (39%), Gaps = 20/224 (8%)
Query: 70 PADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE-----SEDESDEE 124
P DG K + + E E +S++ + + E S+ +E
Sbjct: 813 PRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQE 872
Query: 125 SEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGL 184
S S + ++++ +E++++ E+ E + E++ + V K++ L
Sbjct: 873 SRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQ-----ELKEKVSSVDKQREQTEIL 927
Query: 185 DLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFK 244
+ S +D +IG HQ T D A +E + K K + + + +
Sbjct: 928 ESSRMRAQD---------IIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIE 978
Query: 245 SSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMA 288
+ + T + ++F ++ +K +K I + +K+ DI + A
Sbjct: 979 RGNIETTSEDGQVFSPKKGQK-KKSIEKKRKKSKGDSDISDEEA 1021
Score = 30.8 bits (68), Expect = 1.8
Identities = 21/105 (20%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
++ E++ ++ E + S +ES +S + ++ D D E + +E +
Sbjct: 465 RDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPE 524
Query: 138 ESEAEEDNQ-EEGESEAEGETEAESEFDPEIEMEAERVAKRKCPD 181
ES + N E S E E+ +E EI + ++ + P+
Sbjct: 525 ESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPE 569
Score = 28.9 bits (63), Expect = 7.0
Identities = 15/87 (17%), Positives = 32/87 (36%), Gaps = 1/87 (1%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136
GK + E +ERE E + + ++ E + ++ D D DS + +
Sbjct: 422 GKRDREKDSREEREYEQDQSSSRDHRDDRE-PRDGRDRRDARDTRDRRELRDSRDMRDSR 480
Query: 137 QESEAEEDNQEEGESEAEGETEAESEF 163
+ + D +E + T ++
Sbjct: 481 EMRDYSRDTKESRDPRDSRSTRDAHDY 507
Score = 28.9 bits (63), Expect = 7.0
Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 28/103 (27%)
Query: 74 EGAGKEEAEVKVEQEREIESEAGEESESE--------------EESESEEESETEEESED 119
E + EA+++ E ER++ES + + + EE+ E +E+ E +D
Sbjct: 1385 ESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDD 1444
Query: 120 ES------------DEESEEDSEEEMEDEQESEAE--EDNQEE 148
ES E E S++E+++ +AE ED Q+E
Sbjct: 1445 ESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDE 1487
Score = 28.5 bits (62), Expect = 9.2
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 75 GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
G +E+ ++K+ +ER ESEEE+ E ET + D D + E +E
Sbjct: 119 GRHREKEDIKITKERT--------PESEEEN---VEWETNRDDSDNGDINYDYVHELSLE 167
Query: 135 -DEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167
Q+ + E E+ E E + E PE+
Sbjct: 168 MKRQKIQRELMKLEQENMEKREEIIIKKEVSPEV 201
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 63.9 bits (154), Expect = 2e-10
Identities = 41/150 (27%), Positives = 68/150 (45%), Gaps = 30/150 (20%)
Query: 59 EYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE-- 116
E + ++ WTP + + +E E S++ +SESE SES E+ E+ EE
Sbjct: 652 EVIELAKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGD 711
Query: 117 -----SEDESDEESEE-----------------------DSEEEMEDEQESEAEEDNQEE 148
SED S E+ E DSE+ ++ ++S+ + + +E
Sbjct: 712 SNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDE 771
Query: 149 GESEAEGETEAESEFDPEIEMEAERVAKRK 178
S + +++ESE +PE E E+ RV K K
Sbjct: 772 SSSIEDSSSDSESESEPESESESRRVTKEK 801
Score = 50.1 bits (118), Expect = 3e-06
Identities = 26/94 (27%), Positives = 47/94 (50%)
Query: 90 EIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEG 149
E+ E ++++E+ +++ EE ED SD S+ +SE E ++ E+ E+
Sbjct: 655 ELAKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNE 714
Query: 150 ESEAEGETEAESEFDPEIEMEAERVAKRKCPDHG 183
+S + +E +SE E +E +R AKR G
Sbjct: 715 DSSEDSSSEQDSESGRESGLENKRTAKRNSKAKG 748
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/88 (34%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESD--EESEEDS 129
D E + E K +R S+A +S+SE+ + E+S+T + S DES E+S DS
Sbjct: 725 DSESGRESGLENKRTAKRN--SKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDS 782
Query: 130 EEEMEDEQESEAEEDNQEEGESEAEGET 157
E E E E ESE+ +E+ + + T
Sbjct: 783 ESESEPESESESRRVTKEKEKKTKQDRT 810
Score = 38.5 bits (88), Expect = 0.009
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEES-EDESDEESEEDS 129
+D E KE + K ES + E+S S+ ESESE ESE+E E ++++++D
Sbjct: 750 SDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTKQDR 809
Query: 130 EEEMEDEQESEAEEDN 145
+D + ++ N
Sbjct: 810 TPLTKDVSLLDLDDFN 825
Score = 32.3 bits (72), Expect = 0.63
Identities = 16/77 (20%), Positives = 34/77 (44%)
Query: 68 TPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEE 127
T + + GK ++E ++ + ++ ES +S +SE+E E E ES+
Sbjct: 739 TAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESRRVT 798
Query: 128 DSEEEMEDEQESEAEED 144
+E+ + + +D
Sbjct: 799 KEKEKKTKQDRTPLTKD 815
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 63.9 bits (154), Expect = 2e-10
Identities = 34/110 (30%), Positives = 60/110 (54%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K+ E E+ER E + +E E E+E E E+E ++ + E +++ E+D E++ E E+
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLS 187
E E E+D +E E E + E E E + EI+ + ++ K + P + S
Sbjct: 438 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 487
Score = 54.3 bits (129), Expect = 2e-07
Identities = 28/96 (29%), Positives = 50/96 (52%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K + +R+ E +E E +E + E+E E E+E E E + +D ++E E ++
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
E + E+D + E E E E + + E E + + E E E+
Sbjct: 426 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461
Score = 52.4 bits (124), Expect = 6e-07
Identities = 25/90 (27%), Positives = 47/90 (52%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131
D E + E E + E+ER + +E E + E + E++ E E E E E D + E++ E+
Sbjct: 394 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 453
Query: 132 EMEDEQESEAEEDNQEEGESEAEGETEAES 161
+ E E+E + ++ E+ + + + T S
Sbjct: 454 DKEKEREKDRSKEIDEKRKKDKKSRTPPRS 483
Score = 46.2 bits (108), Expect = 4e-05
Identities = 25/98 (25%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEE--MED 135
K+ ++ + ++ S + ++ + E E+E E++ E E + E E + E+E
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
+++ E E+D +++ E + E E E E E D + E E E+
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 453
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/100 (22%), Positives = 40/100 (40%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138
+E E E+++E + E E E E++ + E+E E ++E E E D E D + + + +
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478
Query: 139 SEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
+ N + E + KRK
Sbjct: 479 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Score = 35.0 bits (79), Expect = 0.098
Identities = 16/77 (20%), Positives = 39/77 (50%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+ E + + ++E++ E E +E E + + E E+E + E+E E + +E +E +++ +
Sbjct: 420 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 479
Query: 138 ESEAEEDNQEEGESEAE 154
+ ++ S E
Sbjct: 480 PPRSYNASRRSRSSSRE 496
Score = 33.5 bits (75), Expect = 0.28
Identities = 21/98 (21%), Positives = 45/98 (45%), Gaps = 2/98 (2%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
++ ++ K S + ++ +S ++ S++ E + S S + ++ E +
Sbjct: 326 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 385
Query: 138 ESEA--EEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
E E E+D ++E E E E E E E + + + E E+
Sbjct: 386 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK 423
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 63.9 bits (154), Expect = 2e-10
Identities = 34/110 (30%), Positives = 60/110 (54%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K+ E E+ER E + +E E E+E E E+E ++ + E +++ E+D E++ E E+
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLS 187
E E E+D +E E E + E E E + EI+ + ++ K + P + S
Sbjct: 322 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371
Score = 54.3 bits (129), Expect = 2e-07
Identities = 28/96 (29%), Positives = 50/96 (52%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K + +R+ E +E E +E + E+E E E+E E E + +D ++E E ++
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309
Query: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
E + E+D + E E E E + + E E + + E E E+
Sbjct: 310 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345
Score = 52.4 bits (124), Expect = 6e-07
Identities = 25/90 (27%), Positives = 47/90 (52%)
Query: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131
D E + E E + E+ER + +E E + E + E++ E E E E E D + E++ E+
Sbjct: 278 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 337
Query: 132 EMEDEQESEAEEDNQEEGESEAEGETEAES 161
+ E E+E + ++ E+ + + + T S
Sbjct: 338 DKEKEREKDRSKEIDEKRKKDKKSRTPPRS 367
Score = 46.2 bits (108), Expect = 4e-05
Identities = 25/98 (25%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEE--MED 135
K+ ++ + ++ S + ++ + E E+E E++ E E + E E + E+E
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 136 EQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
+++ E E+D +++ E + E E E E E D + E E E+
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 337
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/100 (22%), Positives = 40/100 (40%)
Query: 79 EEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138
+E E E+++E + E E E E++ + E+E E ++E E E D E D + + + +
Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362
Query: 139 SEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
+ N + E + KRK
Sbjct: 363 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Score = 35.0 bits (79), Expect = 0.098
Identities = 16/77 (20%), Positives = 39/77 (50%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
+ E + + ++E++ E E +E E + + E E+E + E+E E + +E +E +++ +
Sbjct: 304 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 363
Query: 138 ESEAEEDNQEEGESEAE 154
+ ++ S E
Sbjct: 364 PPRSYNASRRSRSSSRE 380
Score = 33.5 bits (75), Expect = 0.28
Identities = 21/98 (21%), Positives = 45/98 (45%), Gaps = 2/98 (2%)
Query: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
++ ++ K S + ++ +S ++ S++ E + S S + ++ E +
Sbjct: 210 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 269
Query: 138 ESEA--EEDNQEEGESEAEGETEAESEFDPEIEMEAER 173
E E E+D ++E E E E E E E + + + E E+
Sbjct: 270 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK 307
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 63.9 bits (154), Expect = 2e-10
Identities = 38/104 (36%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 78 KEEAEVKVEQEREIESEAGEESE----SEEESESEEESETEEESEDESDEESEEDSEEEM 133
+E E VE++ E+E +A E+ E EEE E EEE E EEE E+E E+ E D +EE
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 134 EDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
D D+ E S +G + S D E + ER R
Sbjct: 262 NDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRAR 305
Score = 62.0 bits (149), Expect = 7e-10
Identities = 49/182 (26%), Positives = 86/182 (47%), Gaps = 11/182 (6%)
Query: 59 EYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE-S 117
E V+ + + G +E E E E G E + EE+ E EE++E +EE
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEE-----GVEEDVEEDEEVEEDAEEDEEVD 226
Query: 118 EDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
ED +EE EE+ EEE E+E+E E E+D +++ E + +T +E+ + + R
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286
Query: 178 KCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIEL 237
G D S +++R+ + P++ G S+ E++ + SK L+ A L
Sbjct: 287 S--GSGTDGSDEKKKERKRARGISPIVFDRSG---SSASESYADQTSKLKYVLQDARFFL 341
Query: 238 VE 239
++
Sbjct: 342 IK 343
Score = 57.0 bits (136), Expect = 2e-08
Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 76 AGKEEAEVKVEQEREIESEAGEESESEEE---SESEEESETEEESEDESDEESEEDSEEE 132
+ KEE +E + E G S+E+ +E+EEE E+ EDE EE E+ EE
Sbjct: 169 SSKEEVN---SEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225
Query: 133 MEDEQESEAEEDNQEEGESEAEGETEAESEFDPE 166
ED +E E EE+ +EE E E E E E + E
Sbjct: 226 DEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
Score = 55.5 bits (132), Expect = 7e-08
Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 13/103 (12%)
Query: 77 GKEEAEVKVEQEREIESEAGEESESEEESESEEES-------------ETEEESEDESDE 123
G E ++V++ S++ +E + EE S+ E+ E EEE +E E
Sbjct: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVE 210
Query: 124 ESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPE 166
E EE E+ EDE+ E E+ +EE E E E E E E E++ +
Sbjct: 211 EDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD 253
Score = 33.9 bits (76), Expect = 0.22
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 13/98 (13%)
Query: 84 KVEQEREIESEAGEESE------SEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
K + ER +S + SE S S + S+ E SE+ + E DEQ
Sbjct: 137 KRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH--ETGSSGSSDEQ 194
Query: 138 ESEAEEDNQEEG---ESEAEGETEAESEFDPEIEMEAE 172
+ E N+EEG + E + E E ++E D E++ + E
Sbjct: 195 GNNTE--NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.123 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,587,941
Number of Sequences: 37866
Number of extensions: 793799
Number of successful extensions: 69330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1847
Number of HSP's successfully gapped in prelim test: 889
Number of HSP's that attempted gapping in prelim test: 9871
Number of HSP's gapped (non-prelim): 23126
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.