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Search of human proteins with 21361591
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361591 transforming growth factor beta 1 induced
transcript 1 isoform 2 [Homo sapiens]
(444 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109638745 transforming growth factor beta 1 induced transcrip... 954 0.0
gi|21361591 transforming growth factor beta 1 induced transcript... 954 0.0
gi|170932516 paxillin isoform 2 [Homo sapiens] 433 e-121
gi|170932514 paxillin isoform 1 [Homo sapiens] 432 e-121
gi|170932518 paxillin isoform 3 [Homo sapiens] 419 e-117
gi|4758670 leupaxin isoform 2 [Homo sapiens] 377 e-105
gi|221316659 leupaxin isoform 1 [Homo sapiens] 374 e-103
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 172 7e-43
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 172 7e-43
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 169 4e-42
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 169 4e-42
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 167 2e-41
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 165 9e-41
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 136 3e-32
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 136 3e-32
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 136 3e-32
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 136 3e-32
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 135 6e-32
gi|58530845 zyxin [Homo sapiens] 122 7e-28
gi|4508047 zyxin [Homo sapiens] 122 7e-28
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 121 1e-27
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 120 3e-27
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 115 1e-25
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 114 2e-25
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 114 2e-25
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 114 2e-25
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens] 112 5e-25
gi|30410801 activator of cAMP-responsive element modulator (CREM... 112 5e-25
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 112 9e-25
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 112 9e-25
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 954 bits (2465), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAP 60
MPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAP
Sbjct: 18 MPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAP 77
Query: 61 PFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPS 120
PFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPS
Sbjct: 78 PFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPS 137
Query: 121 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPE 180
LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPE
Sbjct: 138 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPE 197
Query: 181 PTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC 240
PTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC
Sbjct: 198 PTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC 257
Query: 241 STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG 300
STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG
Sbjct: 258 STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG 317
Query: 301 EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA 360
EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA
Sbjct: 318 EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA 377
Query: 361 PFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRP 420
PFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRP
Sbjct: 378 PFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRP 437
Query: 421 LTKGSFQERAGKPYCQPCFLKLFG 444
LTKGSFQERAGKPYCQPCFLKLFG
Sbjct: 438 LTKGSFQERAGKPYCQPCFLKLFG 461
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 954 bits (2465), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAP 60
MPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAP
Sbjct: 1 MPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAP 60
Query: 61 PFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPS 120
PFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPS
Sbjct: 61 PFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPS 120
Query: 121 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPE 180
LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPE
Sbjct: 121 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPE 180
Query: 181 PTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC 240
PTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC
Sbjct: 181 PTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC 240
Query: 241 STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG 300
STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG
Sbjct: 241 STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG 300
Query: 301 EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA 360
EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA
Sbjct: 301 EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA 360
Query: 361 PFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRP 420
PFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRP
Sbjct: 361 PFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRP 420
Query: 421 LTKGSFQERAGKPYCQPCFLKLFG 444
LTKGSFQERAGKPYCQPCFLKLFG
Sbjct: 421 LTKGSFQERAGKPYCQPCFLKLFG 444
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 433 bits (1113), Expect = e-121
Identities = 231/497 (46%), Positives = 292/497 (58%), Gaps = 86/497 (17%)
Query: 13 EPLTPPPSYGHQPQTGS--------GESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSS 64
+P + P YG +T S G G+++H+YS K +S +P+ P S
Sbjct: 80 QPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSFPNKQKSAEPS----PTVMS 135
Query: 65 SSGVLGTGLCELDRLLQELNATQFNI----TDEIMSQ------------FPSSKVASGEQ 108
+S LG+ L ELDRLL ELNA Q N DE S P + G +
Sbjct: 136 TS--LGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 193
Query: 109 KEDQSEDKK-----------RPSLPS----------SPSPGLP----------------- 130
+++K RPS+ S SP P +
Sbjct: 194 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 253
Query: 131 --KASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP--EPTGKGS 186
+ SA+SAT ELD LMASLSDF+ A G T GS SPP P
Sbjct: 254 QTRISASSATRELDELMASLSDFKFM----AQGKT----------GSSSPPGGPPKPGSQ 299
Query: 187 LDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGG 246
LD+MLG LQSDL++ GV T AKG+CG+C KPIAGQVVTA+G+ WHPEHFVC C +G
Sbjct: 300 LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGS 359
Query: 247 SSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDE 306
+FFE+DG P+C + Y FSPRC +CN PI K+VTAL WHPEHF C CG FG E
Sbjct: 360 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPE 419
Query: 307 GFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGS 366
GFHE++G+ YCR+D+ +FAP+C GC IL+NYISAL+ LWHP+CFVCRECF PF GS
Sbjct: 420 GFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGS 479
Query: 367 FFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSF 426
FFEH+G+P CE H+H RRGSLC+ C P+TGRC++A+ ++FHP+HF C FCL+ L KG+F
Sbjct: 480 FFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTF 539
Query: 427 QERAGKPYCQPCFLKLF 443
+E+ KPYCQ CFLKLF
Sbjct: 540 KEQNDKPYCQNCFLKLF 556
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 432 bits (1111), Expect = e-121
Identities = 232/517 (44%), Positives = 296/517 (57%), Gaps = 92/517 (17%)
Query: 13 EPLTPPPSYGHQPQTGS--------GESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSS 64
+P + P YG +T S G G+++H+YS K +S +P+ P S
Sbjct: 80 QPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSFPNKQKSAEPS----PTVMS 135
Query: 65 SSGVLGTGLCELDRLLQELNATQFNI----TDEIMSQ------------FPSSKVASGEQ 108
+S LG+ L ELDRLL ELNA Q N DE S P + G +
Sbjct: 136 TS--LGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 193
Query: 109 KEDQSEDKK-----------RPSLPS----------SPSPGLP----------------- 130
+++K RPS+ S SP P +
Sbjct: 194 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 253
Query: 131 --KASATSATLELDRLMASLSDFRVQN-------------HLPASGPTQPP-------VV 168
+ SA+SAT ELD LMASLSDF++Q P G P +
Sbjct: 254 QTRISASSATRELDELMASLSDFKIQGLEQRADGERCWAAGWPRDGGRSSPGGQDEGGFM 313
Query: 169 SSTNEGSPSPP--EPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTAL 226
+ GS SPP P LD+MLG LQSDL++ GV T AKG+CG+C KPIAGQVVTA+
Sbjct: 314 AQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAM 373
Query: 227 GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALG 286
G+ WHPEHFVC C +G +FFE+DG P+C + Y FSPRC +CN PI K+VTAL
Sbjct: 374 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 433
Query: 287 THWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSA 346
WHPEHF C CG FG EGFHE++G+ YCR+D+ +FAP+C GC IL+NYISAL+
Sbjct: 434 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNT 493
Query: 347 LWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRR 406
LWHP+CFVCRECF PF GSFFEH+G+P CE H+H RRGSLC+ C P+TGRC++A+ ++
Sbjct: 494 LWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKK 553
Query: 407 FHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
FHP+HF C FCL+ L KG+F+E+ KPYCQ CFLKLF
Sbjct: 554 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 419 bits (1076), Expect = e-117
Identities = 208/428 (48%), Positives = 265/428 (61%), Gaps = 32/428 (7%)
Query: 18 PPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGVLGTGLCELD 77
PP + P + S G LY P + P A P + G
Sbjct: 26 PPGF---PADEANSSPPLPGALSPLYGV---PETNSPLGGKAGPLTKEKPKRNGG----- 74
Query: 78 RLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSA 137
R L+++ + ++ DE+ S PS A + + S ++ S + SA+SA
Sbjct: 75 RGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQT-----RISASSA 129
Query: 138 TLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP--EPTGKGSLDTMLGLLQ 195
T ELD LMASLSDF+ A G T GS SPP P LD+MLG LQ
Sbjct: 130 TRELDELMASLSDFKFM----AQGKT----------GSSSPPGGPPKPGSQLDSMLGSLQ 175
Query: 196 SDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGA 255
SDL++ GV T AKG+CG+C KPIAGQVVTA+G+ WHPEHFVC C +G +FFE+DG
Sbjct: 176 SDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQ 235
Query: 256 PFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRP 315
P+C + Y FSPRC +CN PI K+VTAL WHPEHF C CG FG EGFHE++G+
Sbjct: 236 PYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKA 295
Query: 316 YCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 375
YCR+D+ +FAP+C GC IL+NYISAL+ LWHP+CFVCRECF PF GSFFEH+G+P
Sbjct: 296 YCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPY 355
Query: 376 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 435
CE H+H RRGSLC+ C P+TGRC++A+ ++FHP+HF C FCL+ L KG+F+E+ KPYC
Sbjct: 356 CEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYC 415
Query: 436 QPCFLKLF 443
Q CFLKLF
Sbjct: 416 QNCFLKLF 423
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 377 bits (969), Expect = e-105
Identities = 180/394 (45%), Positives = 236/394 (59%), Gaps = 37/394 (9%)
Query: 75 ELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSP------- 127
ELD LL+EL + +DE + P ++ + E + S+ + SP
Sbjct: 3 ELDALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVY 62
Query: 128 -----------------GLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSS 170
P S TSA +LD LMA L++ Q V
Sbjct: 63 TTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM------------QAKVAVR 110
Query: 171 TNEGSPSPPEPTG-KGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRA 229
+ G P+ K SLD+MLG L+ +L G+ T KG C SC KPIAG+V+ ALG++
Sbjct: 111 ADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQS 170
Query: 230 WHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHW 289
WHPEHFVC C +G S FFE+ G +CP Y + FSPRC +C PI K++TA+ W
Sbjct: 171 WHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTW 230
Query: 290 HPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWH 349
HPEHF C CGE FG EGFHE++ +PYCR+DFL +F+P+C GC P+L+NY+SA+ +WH
Sbjct: 231 HPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWH 290
Query: 350 PDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHP 409
P+CFVC +CF FS GSFFE +GRP CE H+H RRG+LC CG P+TGRC+SA+G +FHP
Sbjct: 291 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHP 350
Query: 410 DHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
+HF C FCL L+KG F+E+ K YCQPCF KLF
Sbjct: 351 EHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 374 bits (960), Expect = e-103
Identities = 178/392 (45%), Positives = 234/392 (59%), Gaps = 37/392 (9%)
Query: 77 DRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSP--------- 127
D LL+EL + +DE + P ++ + E + S+ + SP
Sbjct: 10 DALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVYTT 69
Query: 128 ---------------GLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTN 172
P S TSA +LD LMA L++ Q V +
Sbjct: 70 NIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM------------QAKVAVRAD 117
Query: 173 EGSPSPPEPTG-KGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWH 231
G P+ K SLD+MLG L+ +L G+ T KG C SC KPIAG+V+ ALG++WH
Sbjct: 118 AGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWH 177
Query: 232 PEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHP 291
PEHFVC C +G S FFE+ G +CP Y + FSPRC +C PI K++TA+ WHP
Sbjct: 178 PEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHP 237
Query: 292 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPD 351
EHF C CGE FG EGFHE++ +PYCR+DFL +F+P+C GC P+L+NY+SA+ +WHP+
Sbjct: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPE 297
Query: 352 CFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDH 411
CFVC +CF FS GSFFE +GRP CE H+H RRG+LC CG P+TGRC+SA+G +FHP+H
Sbjct: 298 CFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEH 357
Query: 412 FTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
F C FCL L+KG F+E+ K YCQPCF KLF
Sbjct: 358 FVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 172 bits (435), Expect = 7e-43
Identities = 81/227 (35%), Positives = 112/227 (49%), Gaps = 19/227 (8%)
Query: 157 LPASGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNK 216
LP GP P P P P +G++ + R + LCG CN
Sbjct: 404 LPRGGPAYTPA-------GPQVP-PLARGTVQR---------AERFPASSRTPLCGHCNN 446
Query: 217 PIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQP 276
I G + A+GR+WHPE F C C T+L F E+ +C CY + F+P C CN
Sbjct: 447 VIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTK 506
Query: 277 IRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI 336
I +++ AL WH F C +C +PFG+ FH +G PYC +D++ LF+ +C GC P+
Sbjct: 507 IMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPV 566
Query: 337 L--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 381
D +I AL WH CF+C C G F+ + RPLC+ H H
Sbjct: 567 EAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
Score = 124 bits (312), Expect = 1e-28
Identities = 60/172 (34%), Positives = 76/172 (44%), Gaps = 2/172 (1%)
Query: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+P CG CN IR + A+G WHPE F C C D F E + YC R + Q FA
Sbjct: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I+ + AL WH CFVC C PF F +G P CE + +
Sbjct: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
Query: 387 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 436
C C PV + + ALG +H F C C L F + +P C+
Sbjct: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
Score = 75.5 bits (184), Expect = 9e-14
Identities = 34/117 (29%), Positives = 50/117 (42%)
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I ++ A+ WHP+ F C C + F E + CE +
Sbjct: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
LCA C + G + AL + +H F C C +P F G+PYC+ ++ LF
Sbjct: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
Score = 50.4 bits (119), Expect = 3e-06
Identities = 21/60 (35%), Positives = 30/60 (50%)
Query: 384 RGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
R LC C + G + A+GR +HP+ FTC +C L F E YC+ C+ + F
Sbjct: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 172 bits (435), Expect = 7e-43
Identities = 81/227 (35%), Positives = 112/227 (49%), Gaps = 19/227 (8%)
Query: 157 LPASGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNK 216
LP GP P P P P +G++ + R + LCG CN
Sbjct: 514 LPRGGPAYTPA-------GPQVP-PLARGTVQR---------AERFPASSRTPLCGHCNN 556
Query: 217 PIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQP 276
I G + A+GR+WHPE F C C T+L F E+ +C CY + F+P C CN
Sbjct: 557 VIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTK 616
Query: 277 IRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI 336
I +++ AL WH F C +C +PFG+ FH +G PYC +D++ LF+ +C GC P+
Sbjct: 617 IMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPV 676
Query: 337 L--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 381
D +I AL WH CF+C C G F+ + RPLC+ H H
Sbjct: 677 EAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 723
Score = 124 bits (312), Expect = 1e-28
Identities = 60/172 (34%), Positives = 76/172 (44%), Gaps = 2/172 (1%)
Query: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+P CG CN IR + A+G WHPE F C C D F E + YC R + Q FA
Sbjct: 548 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 607
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I+ + AL WH CFVC C PF F +G P CE + +
Sbjct: 608 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 667
Query: 387 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 436
C C PV + + ALG +H F C C L F + +P C+
Sbjct: 668 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719
Score = 75.5 bits (184), Expect = 9e-14
Identities = 34/117 (29%), Positives = 50/117 (42%)
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I ++ A+ WHP+ F C C + F E + CE +
Sbjct: 549 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 608
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
LCA C + G + AL + +H F C C +P F G+PYC+ ++ LF
Sbjct: 609 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 665
Score = 50.4 bits (119), Expect = 3e-06
Identities = 21/60 (35%), Positives = 30/60 (50%)
Query: 384 RGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
R LC C + G + A+GR +HP+ FTC +C L F E YC+ C+ + F
Sbjct: 547 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 606
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 169 bits (429), Expect = 4e-42
Identities = 97/298 (32%), Positives = 149/298 (50%), Gaps = 24/298 (8%)
Query: 109 KEDQSEDKKRPSLPSSPSPGLPKASATSATL--ELDRL------MASLSDFRVQNHLPAS 160
KE ++++ K+ + PSP L + A++ ++ LD + SL+ + ++
Sbjct: 187 KESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGST 246
Query: 161 GPTQPPVVSSTNEGSPSPPE----PTGKGSL---DTMLGLLQSD----LSRRG--VPTQA 207
G + P N+G PS T GS+ ++ LG Q L +R +P
Sbjct: 247 GVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGK 306
Query: 208 KG-LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 266
+ +C CN+ I G + ALG++WHPE F C C + F E+ GA +C CY + F
Sbjct: 307 RTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
Query: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+P CG C + I ++++AL WH F CV+CG+P + FH +G PYC D+ LF
Sbjct: 367 APECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
Query: 327 PRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHA 382
C GC+ PI D ++ AL WH CFVC C G +FF + +PLC+ H H+
Sbjct: 427 TICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHS 484
Score = 72.4 bits (176), Expect = 8e-13
Identities = 36/118 (30%), Positives = 51/118 (43%)
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I ++ AL WHP+ F C C + F E +G CE +
Sbjct: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444
C C + G +SAL + +H F C C +P+ F G+PYC+ + LFG
Sbjct: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
Score = 50.4 bits (119), Expect = 3e-06
Identities = 21/61 (34%), Positives = 31/61 (50%)
Query: 383 RRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKL 442
+R +CA C + G + ALG+ +HP+ F C C + F E G YC+ C+ K
Sbjct: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
Query: 443 F 443
F
Sbjct: 366 F 366
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 169 bits (429), Expect = 4e-42
Identities = 97/298 (32%), Positives = 149/298 (50%), Gaps = 24/298 (8%)
Query: 109 KEDQSEDKKRPSLPSSPSPGLPKASATSATL--ELDRL------MASLSDFRVQNHLPAS 160
KE ++++ K+ + PSP L + A++ ++ LD + SL+ + ++
Sbjct: 296 KESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGST 355
Query: 161 GPTQPPVVSSTNEGSPSPPE----PTGKGSL---DTMLGLLQSD----LSRRG--VPTQA 207
G + P N+G PS T GS+ ++ LG Q L +R +P
Sbjct: 356 GVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGK 415
Query: 208 KG-LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 266
+ +C CN+ I G + ALG++WHPE F C C + F E+ GA +C CY + F
Sbjct: 416 RTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 475
Query: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+P CG C + I ++++AL WH F CV+CG+P + FH +G PYC D+ LF
Sbjct: 476 APECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 535
Query: 327 PRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHA 382
C GC+ PI D ++ AL WH CFVC C G +FF + +PLC+ H H+
Sbjct: 536 TICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHS 593
Score = 140 bits (353), Expect = 2e-33
Identities = 122/447 (27%), Positives = 176/447 (39%), Gaps = 65/447 (14%)
Query: 43 YSTVCKPRSPKPAAPAAPPFSSSSGVLGTGLCELDRLLQELNA--TQFNI----TDEIMS 96
++T SP P A PP ++SG+ D+ L+A T N+ T +
Sbjct: 154 HATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSVC 213
Query: 97 QFPSSKVASGEQKEDQSEDKKRPSLPS-------SPSPGLPKASATSATLELDRLMASLS 149
S ++A G+++ Q + K++ P + +P S S RL+
Sbjct: 214 SETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKK----RLIEDTE 269
Query: 150 DFRVQNHLPASGPTQPP---------------------VVSSTNEGSPSPPEPTGKGSLD 188
D+R P +G TQ + N PSP + S
Sbjct: 270 DWR-----PRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTR 324
Query: 189 TMLGLLQSDLSRR-GV----------PTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFV- 236
+M L S S R GV P + G+ S + Q V + GR + +
Sbjct: 325 SMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSG 384
Query: 237 -CGGCSTALGGSSFFEKDG----APFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHP 291
++ALG + ++D A P + +P C CNQ IR + ALG WHP
Sbjct: 385 SVAPANSALGQTQPSDQDTLVQRAEHIPA---GKRTPMCAHCNQVIRGPFLVALGKSWHP 441
Query: 292 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPD 351
E F C C GF E +G YC + + FAP C CQ IL ISAL WH
Sbjct: 442 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVS 501
Query: 352 CFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTG--RCVSALGRRFHP 409
CFVC C P F +G P CE ++A G++C C P+ + ALG +H
Sbjct: 502 CFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHD 561
Query: 410 DHFTCTFCLRPLTKGSFQERAGKPYCQ 436
F C+ C L +F + KP C+
Sbjct: 562 TCFVCSVCCESLEGQTFFSKKDKPLCK 588
Score = 72.4 bits (176), Expect = 8e-13
Identities = 36/118 (30%), Positives = 51/118 (43%)
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I ++ AL WHP+ F C C + F E +G CE +
Sbjct: 418 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444
C C + G +SAL + +H F C C +P+ F G+PYC+ + LFG
Sbjct: 478 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 535
Score = 50.4 bits (119), Expect = 3e-06
Identities = 21/61 (34%), Positives = 31/61 (50%)
Query: 383 RRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKL 442
+R +CA C + G + ALG+ +HP+ F C C + F E G YC+ C+ K
Sbjct: 415 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 474
Query: 443 F 443
F
Sbjct: 475 F 475
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 167 bits (422), Expect = 2e-41
Identities = 114/387 (29%), Positives = 164/387 (42%), Gaps = 42/387 (10%)
Query: 9 ERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGV 68
++ + P PP Y P +++ G S ++ +P P P S +
Sbjct: 92 QKASAPAADPPRYTFAPSVSLNKTARPFGAPPPADSA--PQQNGQPLRPLVPDASKQRLM 149
Query: 69 L---------GTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRP 119
GTG R+L L T+F + SS+V E S
Sbjct: 150 ENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPAS------ 203
Query: 120 SLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP 179
S P P PG S TS R ++ + + P T T P+ P
Sbjct: 204 STPQEPWPGPTAPSPTS------RPPWAVDPAFAERYAPDKTSTV-----LTRHSQPATP 252
Query: 180 EPTGKGSLDTMLGLLQSDLSRRGVPTQAKG-----LCGSCNKPIAGQVVTALGRAWHPEH 234
P L + ++Q+ + GVP +C C+K I G+ + ALG A+HPE
Sbjct: 253 TP-----LQSRTSIVQA--AAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEE 305
Query: 235 FVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHF 294
FVC C L FFE+ GA FCP CY R++P C C + I +++ AL WH F
Sbjct: 306 FVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCF 365
Query: 295 CCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI--LDNYISALSALWHPDC 352
C +C P + F+ EG PYC RD+ ++F +C GC I D ++ AL WH C
Sbjct: 366 TCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTC 425
Query: 353 FVCRECFAPFSGGSFFEHEGRPLCENH 379
FVC C G +F+ + RPLC++H
Sbjct: 426 FVCAICQINLEGKTFYSKKDRPLCKSH 452
Score = 112 bits (280), Expect = 7e-25
Identities = 55/172 (31%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+P C C++ IR + + ALG +HPE F C CG+ + GF E +G +C + +A
Sbjct: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C+ I + AL WH CF C C P +F+ EG P CE + G+
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
Query: 387 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 436
C C + R + ALG +H F C C L +F + +P C+
Sbjct: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
Score = 84.7 bits (208), Expect = 2e-16
Identities = 41/118 (34%), Positives = 55/118 (46%)
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I Y+ AL +HP+ FVC +C G FFE +G C + R
Sbjct: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444
CA C +TG + AL +H FTC C P+ +F G PYC+ + K+FG
Sbjct: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 165 bits (417), Expect = 9e-41
Identities = 103/317 (32%), Positives = 143/317 (45%), Gaps = 31/317 (9%)
Query: 70 GTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGL 129
GTG R+L L T+F + SS+V E S S P P PG
Sbjct: 126 GTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPAS------STPQEPWPGP 179
Query: 130 PKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPEPTGKGSLDT 189
S TS R ++ + + P T T P+ P P L +
Sbjct: 180 TAPSPTS------RPPWAVDPAFAERYAPDKTSTV-----LTRHSQPATPTP-----LQS 223
Query: 190 MLGLLQSDLSRRGVPTQAKG-----LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTAL 244
++Q+ + GVP +C C+K I G+ + ALG A+HPE FVC C L
Sbjct: 224 RTSIVQA--AAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVL 281
Query: 245 GGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFG 304
FFE+ GA FCP CY R++P C C + I +++ AL WH F C +C P
Sbjct: 282 EEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIR 341
Query: 305 DEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI--LDNYISALSALWHPDCFVCRECFAPF 362
+ F+ EG PYC RD+ ++F +C GC I D ++ AL WH CFVC C
Sbjct: 342 NRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINL 401
Query: 363 SGGSFFEHEGRPLCENH 379
G +F+ + RPLC++H
Sbjct: 402 EGKTFYSKKDRPLCKSH 418
Score = 112 bits (280), Expect = 7e-25
Identities = 55/172 (31%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+P C C++ IR + + ALG +HPE F C CG+ + GF E +G +C + +A
Sbjct: 245 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C+ I + AL WH CF C C P +F+ EG P CE + G+
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 364
Query: 387 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 436
C C + R + ALG +H F C C L +F + +P C+
Sbjct: 365 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416
Score = 84.7 bits (208), Expect = 2e-16
Identities = 41/118 (34%), Positives = 55/118 (46%)
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
P C C I Y+ AL +HP+ FVC +C G FFE +G C + R
Sbjct: 246 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444
CA C +TG + AL +H FTC C P+ +F G PYC+ + K+FG
Sbjct: 306 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 363
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 136 bits (343), Expect = 3e-32
Identities = 76/237 (32%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269
CGSC + I G+V+ A+ WHP F C C L F + G C C+ +
Sbjct: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
Query: 270 ----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLF 325
C C+ I + + +HP+HF C CG+ E E +G YC ++
Sbjct: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 216
Query: 326 APRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRG 385
P C C+ PI ++AL WH + FVC +C PF G +E +G CE H++ G
Sbjct: 217 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 276
Query: 386 SLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 441
+C C + G VSAL + + F+C+ C LT K F E KP C+ C+ K
Sbjct: 277 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
Score = 120 bits (302), Expect = 2e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 207 AKGLCGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264
A +C C A ++V + G +H FVC C F+E +G +C +
Sbjct: 33 ANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQM 92
Query: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319
F+P CG C + I +++ A+ +WHP F C C D GF + GR C R
Sbjct: 93 LFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNRE 152
Query: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
L CQ C I + + S +HPD F C C + + E +G C
Sbjct: 153 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPC 211
Query: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
+C C P+ GR V+ALG+++H +HF C C +P E+ G YC+ +
Sbjct: 212 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 271
Query: 440 LKLFG 444
+LFG
Sbjct: 272 NQLFG 276
Score = 115 bits (288), Expect = 8e-26
Identities = 61/177 (34%), Positives = 87/177 (49%), Gaps = 6/177 (3%)
Query: 206 QAKGL----CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
+AKGL C C+ I Q + A+HP+HF C C L + E G +C C
Sbjct: 153 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPC 211
Query: 262 YFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDF 321
+ + P CG C +PI ++V ALG WH EHF C C +PF +E++G YC +
Sbjct: 212 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 271
Query: 322 LQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 377
QLF C C I + +SAL+ W CF C C + + F E + +P+C+
Sbjct: 272 NQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 328
Score = 114 bits (284), Expect = 2e-25
Identities = 67/207 (32%), Positives = 93/207 (44%), Gaps = 16/207 (7%)
Query: 241 STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG 300
+ AL S+ + C C RFSP ++V + G +H F C C
Sbjct: 20 AAALRWSNMSDALANAVCQRCQ-ARFSPA---------ERIVNSNGELYHEHCFVCAQCF 69
Query: 301 EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA 360
PF + F+E EGR YC DF LFAP C C I+ I A++ WHP CF C C
Sbjct: 70 RPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDV 129
Query: 361 PFSGGSFFEHEGRPLCENHFHARRGS-----LCATCGLPVTGRCVSALGRRFHPDHFTCT 415
+ F ++ GR LC + + +C C L + + + +HPDHF CT
Sbjct: 130 ELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCT 189
Query: 416 FCLRPLTKGSFQERAGKPYCQPCFLKL 442
C + LT +E G+ YC PC K+
Sbjct: 190 HCGKELT-AEARELKGELYCLPCHDKM 215
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 136 bits (343), Expect = 3e-32
Identities = 76/237 (32%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269
CGSC + I G+V+ A+ WHP F C C L F + G C C+ +
Sbjct: 71 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 130
Query: 270 ----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLF 325
C C+ I + + +HP+HF C CG+ E E +G YC ++
Sbjct: 131 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 189
Query: 326 APRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRG 385
P C C+ PI ++AL WH + FVC +C PF G +E +G CE H++ G
Sbjct: 190 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 249
Query: 386 SLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 441
+C C + G VSAL + + F+C+ C LT K F E KP C+ C+ K
Sbjct: 250 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306
Score = 120 bits (302), Expect = 2e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 207 AKGLCGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264
A +C C A ++V + G +H FVC C F+E +G +C +
Sbjct: 6 ANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQM 65
Query: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319
F+P CG C + I +++ A+ +WHP F C C D GF + GR C R
Sbjct: 66 LFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNRE 125
Query: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
L CQ C I + + S +HPD F C C + + E +G C
Sbjct: 126 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPC 184
Query: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
+C C P+ GR V+ALG+++H +HF C C +P E+ G YC+ +
Sbjct: 185 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 244
Query: 440 LKLFG 444
+LFG
Sbjct: 245 NQLFG 249
Score = 115 bits (288), Expect = 8e-26
Identities = 61/177 (34%), Positives = 87/177 (49%), Gaps = 6/177 (3%)
Query: 206 QAKGL----CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
+AKGL C C+ I Q + A+HP+HF C C L + E G +C C
Sbjct: 126 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPC 184
Query: 262 YFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDF 321
+ + P CG C +PI ++V ALG WH EHF C C +PF +E++G YC +
Sbjct: 185 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 244
Query: 322 LQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 377
QLF C C I + +SAL+ W CF C C + + F E + +P+C+
Sbjct: 245 NQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 301
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 136 bits (343), Expect = 3e-32
Identities = 76/237 (32%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269
CGSC + I G+V+ A+ WHP F C C L F + G C C+ +
Sbjct: 76 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 135
Query: 270 ----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLF 325
C C+ I + + +HP+HF C CG+ E E +G YC ++
Sbjct: 136 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 194
Query: 326 APRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRG 385
P C C+ PI ++AL WH + FVC +C PF G +E +G CE H++ G
Sbjct: 195 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 254
Query: 386 SLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 441
+C C + G VSAL + + F+C+ C LT K F E KP C+ C+ K
Sbjct: 255 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311
Score = 120 bits (302), Expect = 2e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 207 AKGLCGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264
A +C C A ++V + G +H FVC C F+E +G +C +
Sbjct: 11 ANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQM 70
Query: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319
F+P CG C + I +++ A+ +WHP F C C D GF + GR C R
Sbjct: 71 LFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNRE 130
Query: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
L CQ C I + + S +HPD F C C + + E +G C
Sbjct: 131 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPC 189
Query: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
+C C P+ GR V+ALG+++H +HF C C +P E+ G YC+ +
Sbjct: 190 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 249
Query: 440 LKLFG 444
+LFG
Sbjct: 250 NQLFG 254
Score = 115 bits (288), Expect = 8e-26
Identities = 61/177 (34%), Positives = 87/177 (49%), Gaps = 6/177 (3%)
Query: 206 QAKGL----CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
+AKGL C C+ I Q + A+HP+HF C C L + E G +C C
Sbjct: 131 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPC 189
Query: 262 YFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDF 321
+ + P CG C +PI ++V ALG WH EHF C C +PF +E++G YC +
Sbjct: 190 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 249
Query: 322 LQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 377
QLF C C I + +SAL+ W CF C C + + F E + +P+C+
Sbjct: 250 NQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 306
Score = 114 bits (285), Expect = 2e-25
Identities = 66/202 (32%), Positives = 91/202 (45%), Gaps = 16/202 (7%)
Query: 246 GSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGD 305
GS+ + C C RFSP ++V + G +H F C C PF +
Sbjct: 3 GSNMSDALANAVCQRCQ-ARFSPA---------ERIVNSNGELYHEHCFVCAQCFRPFPE 52
Query: 306 EGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGG 365
F+E EGR YC DF LFAP C C I+ I A++ WHP CF C C +
Sbjct: 53 GLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADL 112
Query: 366 SFFEHEGRPLCENHFHARRGS-----LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRP 420
F ++ GR LC + + +C C L + + + +HPDHF CT C +
Sbjct: 113 GFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 172
Query: 421 LTKGSFQERAGKPYCQPCFLKL 442
LT +E G+ YC PC K+
Sbjct: 173 LT-AEARELKGELYCLPCHDKM 193
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 136 bits (343), Expect = 3e-32
Identities = 76/237 (32%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269
CGSC + I G+V+ A+ WHP F C C L F + G C C+ +
Sbjct: 100 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 159
Query: 270 ----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLF 325
C C+ I + + +HP+HF C CG+ E E +G YC ++
Sbjct: 160 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 218
Query: 326 APRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRG 385
P C C+ PI ++AL WH + FVC +C PF G +E +G CE H++ G
Sbjct: 219 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 278
Query: 386 SLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 441
+C C + G VSAL + + F+C+ C LT K F E KP C+ C+ K
Sbjct: 279 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335
Score = 120 bits (302), Expect = 2e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 207 AKGLCGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264
A +C C A ++V + G +H FVC C F+E +G +C +
Sbjct: 35 ANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQM 94
Query: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319
F+P CG C + I +++ A+ +WHP F C C D GF + GR C R
Sbjct: 95 LFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNRE 154
Query: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
L CQ C I + + S +HPD F C C + + E +G C
Sbjct: 155 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPC 213
Query: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
+C C P+ GR V+ALG+++H +HF C C +P E+ G YC+ +
Sbjct: 214 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 273
Query: 440 LKLFG 444
+LFG
Sbjct: 274 NQLFG 278
Score = 115 bits (288), Expect = 8e-26
Identities = 61/177 (34%), Positives = 87/177 (49%), Gaps = 6/177 (3%)
Query: 206 QAKGL----CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
+AKGL C C+ I Q + A+HP+HF C C L + E G +C C
Sbjct: 155 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPC 213
Query: 262 YFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDF 321
+ + P CG C +PI ++V ALG WH EHF C C +PF +E++G YC +
Sbjct: 214 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 273
Query: 322 LQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 377
QLF C C I + +SAL+ W CF C C + + F E + +P+C+
Sbjct: 274 NQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 330
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 135 bits (341), Expect = 6e-32
Identities = 75/238 (31%), Positives = 111/238 (46%), Gaps = 9/238 (3%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269
C C + I G+V+ A+ +WHPE F C C L F + G C C+ R R
Sbjct: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH-NREKARG 129
Query: 270 -----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQL 324
C C+ I + + +HP+HF C +CG+ + E +G YC ++
Sbjct: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188
Query: 325 FAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARR 384
P C C+ PI ++A+ WH + FVC +C PF G +E +G CE H++
Sbjct: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
Query: 385 GSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 441
G +C C + G VSAL + + + F C+ C LT K F E KP C+ C+ K
Sbjct: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
Score = 120 bits (300), Expect = 3e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 207 AKGLCGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264
A C C A ++V + G +H + FVC C F+E +G +C +
Sbjct: 6 ASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQM 65
Query: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319
F+P C C + I +++ A+ WHPE F C C E D GF + GR C R
Sbjct: 66 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE 125
Query: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
L CQ C I + + + +HPD F C C + + E +G C
Sbjct: 126 KARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPC 184
Query: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
+C C P+ GR V+A+G+++H +HF C C +P ER G YC+ +
Sbjct: 185 HDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHY 244
Query: 440 LKLFG 444
+LFG
Sbjct: 245 NQLFG 249
Score = 114 bits (286), Expect = 1e-25
Identities = 57/171 (33%), Positives = 83/171 (48%), Gaps = 2/171 (1%)
Query: 208 KGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 267
K +C C+ I Q + +HP+HF C C L + E G +C C+ +
Sbjct: 132 KYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAR-ELKGELYCLPCHDKMGV 190
Query: 268 PRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
P CG C +PI ++V A+G WH EHF C C +PF +ER+G YC + QLF
Sbjct: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
Query: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 377
C C I + +SAL+ W +CF C C + F E + +P+C+
Sbjct: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCK 301
Score = 89.0 bits (219), Expect = 8e-18
Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 324 LFAPRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 381
L + C+ C+G + +++ L+H CFVC +CF F G F+E EGR CE+ F
Sbjct: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
Query: 382 ARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
C CG + GR + A+ +HP+ F C C L F + AG+ C+PC
Sbjct: 65 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 121
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 122 bits (306), Expect = 7e-28
Identities = 84/302 (27%), Positives = 126/302 (41%), Gaps = 27/302 (8%)
Query: 100 SSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPA 159
+SK + G S+ ++ P + S G S T R + + + H
Sbjct: 277 ASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQE---KQH--- 330
Query: 160 SGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQ----AKGLCGSCN 215
P PP + SP P P ++ + L Q + P + LCG C+
Sbjct: 331 --PVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCH 388
Query: 216 KPIAGQ--VVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFC 273
+P+A V ALG+ +H F C C+ L G F+ +GAP+C CY + +C C
Sbjct: 389 QPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLE-KCNTC 447
Query: 274 NQPIRHKMVTALGTHWHPEHFCCVSCGEPF-GDEGFHEREGRPYCRRDFLQLFAPRCQGC 332
+PI +M+ A G +HP F CV C P G ++ RP+C D+ + +APRC C
Sbjct: 448 GEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVC 507
Query: 333 QGPILDN-------YISALSALWHPDCFVCRECFAPFS----GGSFFEHEGRPLCENHFH 381
PI+ + AL +H C+ C +C P S F +G LC
Sbjct: 508 SEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHT 567
Query: 382 AR 383
AR
Sbjct: 568 AR 569
Score = 91.7 bits (226), Expect = 1e-18
Identities = 53/163 (32%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Query: 270 CGFCNQPIRHKM--VTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
CG C+QP+ V ALG +H F C C + + F+ EG PYC +
Sbjct: 384 CGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLE- 442
Query: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFF-EHEGRPLCENHFHARRGS 386
+C C PI D + A +HP CF C C P G SF + RP C +H +
Sbjct: 443 KCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAP 502
Query: 387 LCATCGLPVT---GRC----VSALGRRFHPDHFTCTFCLRPLT 422
C+ C P+ GR V AL + FH + C C +PL+
Sbjct: 503 RCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLS 545
Score = 83.6 bits (205), Expect = 3e-16
Identities = 43/118 (36%), Positives = 59/118 (50%), Gaps = 4/118 (3%)
Query: 329 CQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
C C P+ + AL L+H CF C +C G F+ EG P CE +
Sbjct: 384 CGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEK 443
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSF-QERAGKPYCQPCFLKLF 443
C TCG P+T R + A G+ +HP FTC C RPL SF ++A +P+C P + K +
Sbjct: 444 -CNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQY 500
Score = 32.3 bits (72), Expect = 0.89
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 114 EDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPA---SGPTQPPVVSS 170
E++ P P P P P+ +S LE+D L + L D + A SG PPV +
Sbjct: 122 EEEGGPEAPIPPPPQ-PREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP 180
Query: 171 TNEGSPSPPEPTGKGSL 187
+ S + P G L
Sbjct: 181 FSSKSSTKPAAGGTAPL 197
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 122 bits (306), Expect = 7e-28
Identities = 84/302 (27%), Positives = 126/302 (41%), Gaps = 27/302 (8%)
Query: 100 SSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPA 159
+SK + G S+ ++ P + S G S T R + + + H
Sbjct: 277 ASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQE---KQH--- 330
Query: 160 SGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQ----AKGLCGSCN 215
P PP + SP P P ++ + L Q + P + LCG C+
Sbjct: 331 --PVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCH 388
Query: 216 KPIAGQ--VVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFC 273
+P+A V ALG+ +H F C C+ L G F+ +GAP+C CY + +C C
Sbjct: 389 QPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLE-KCNTC 447
Query: 274 NQPIRHKMVTALGTHWHPEHFCCVSCGEPF-GDEGFHEREGRPYCRRDFLQLFAPRCQGC 332
+PI +M+ A G +HP F CV C P G ++ RP+C D+ + +APRC C
Sbjct: 448 GEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVC 507
Query: 333 QGPILDN-------YISALSALWHPDCFVCRECFAPFS----GGSFFEHEGRPLCENHFH 381
PI+ + AL +H C+ C +C P S F +G LC
Sbjct: 508 SEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHT 567
Query: 382 AR 383
AR
Sbjct: 568 AR 569
Score = 91.7 bits (226), Expect = 1e-18
Identities = 53/163 (32%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Query: 270 CGFCNQPIRHKM--VTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
CG C+QP+ V ALG +H F C C + + F+ EG PYC +
Sbjct: 384 CGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLE- 442
Query: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFF-EHEGRPLCENHFHARRGS 386
+C C PI D + A +HP CF C C P G SF + RP C +H +
Sbjct: 443 KCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAP 502
Query: 387 LCATCGLPVT---GRC----VSALGRRFHPDHFTCTFCLRPLT 422
C+ C P+ GR V AL + FH + C C +PL+
Sbjct: 503 RCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLS 545
Score = 83.6 bits (205), Expect = 3e-16
Identities = 43/118 (36%), Positives = 59/118 (50%), Gaps = 4/118 (3%)
Query: 329 CQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
C C P+ + AL L+H CF C +C G F+ EG P CE +
Sbjct: 384 CGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEK 443
Query: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSF-QERAGKPYCQPCFLKLF 443
C TCG P+T R + A G+ +HP FTC C RPL SF ++A +P+C P + K +
Sbjct: 444 -CNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQY 500
Score = 32.3 bits (72), Expect = 0.89
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 114 EDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPA---SGPTQPPVVSS 170
E++ P P P P P+ +S LE+D L + L D + A SG PPV +
Sbjct: 122 EEEGGPEAPIPPPPQ-PREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP 180
Query: 171 TNEGSPSPPEPTGKGSL 187
+ S + P G L
Sbjct: 181 FSSKSSTKPAAGGTAPL 197
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 121 bits (304), Expect = 1e-27
Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 36/249 (14%)
Query: 121 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPT-QPPVVSSTNEGSPSPP 179
LPS P ++ A LE LS PA GP+ QP + E P PP
Sbjct: 115 LPSEEEAPAPMGASLIADLE----QLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPP 170
Query: 180 -EPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQ--VVTALGRAWHPEHFV 236
EP KG+ + +C C+K ++ + V A+ R +H + F
Sbjct: 171 AEPVEKGA--------------------STDICAFCHKTVSPRELAVEAMKRQYHAQCFT 210
Query: 237 CGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCC 296
C C L G SF++KDG P C CY + RCG C + +R ++ ALG +HP F C
Sbjct: 211 CRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTC 269
Query: 297 VSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQGCQGPILDN------YISALSALWH 349
V+C GDE F + YC DF + FAP C C+ PI+ I + +H
Sbjct: 270 VTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFH 329
Query: 350 PDCFVCREC 358
+C+ C +C
Sbjct: 330 ENCYRCEDC 338
Score = 83.6 bits (205), Expect = 3e-16
Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 270 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
C FC++ + R V A+ +H + F C +C + F++++GRP C + Q
Sbjct: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 241
Query: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 386
RC C + D+ I AL +HP CF C C SF + C + F+ +
Sbjct: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 301
Query: 387 LCATCGLPVTGR------CVSALGRRFHPDHFTCTFC-----LRPLTKGSFQERAGKPYC 435
+C+ C P+ R + +GR FH + + C C + P +G + +C
Sbjct: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLN-NHLFC 360
Query: 436 QPCFLK 441
+PC +K
Sbjct: 361 KPCHVK 366
Score = 71.6 bits (174), Expect = 1e-12
Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 341 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 400
+ A+ +H CF CR C +G SF++ +GRPLCE + C CG V +
Sbjct: 197 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 255
Query: 401 SALGRRFHPDHFTCTFCLRPLTKGSFQ-ERAGKPYCQPCFLKLF 443
ALG+ FHP FTC C R + SF + YC F + F
Sbjct: 256 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 299
Score = 49.3 bits (116), Expect = 7e-06
Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
Query: 387 LCATCGLPVTGR--CVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
+CA C V+ R V A+ R++H FTC C R L SF ++ G+P C+PC+
Sbjct: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY 236
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 120 bits (300), Expect = 3e-27
Identities = 57/173 (32%), Positives = 80/173 (46%), Gaps = 6/173 (3%)
Query: 211 CGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
C +C + + + + G+ WH F+C GC LG SF GA +C CY +F+P
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
Query: 269 RCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPR 328
RC C++ + VT WH E C C P + F R+ PYC F +LFAP+
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
Query: 329 CQGCQGPIL----DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCE 377
C C+ PI+ Y+S WH +CF C C G F + LC+
Sbjct: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
Score = 110 bits (276), Expect = 2e-24
Identities = 61/217 (28%), Positives = 87/217 (40%), Gaps = 6/217 (2%)
Query: 228 RAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTAL 285
R +H F C C +L F +D C +CY FS +C C + + + +
Sbjct: 59 RHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYG 118
Query: 286 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALS 345
G WH F C C +P G F +G YC + FAPRC C + ++
Sbjct: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
Query: 346 ALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVT----GRCVS 401
WH +C VC C P +G F + P C F C++C P+ G+ VS
Sbjct: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
Query: 402 ALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
R +H + F+C C L F + CQ C
Sbjct: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
Score = 109 bits (273), Expect = 4e-24
Identities = 60/215 (27%), Positives = 87/215 (40%), Gaps = 4/215 (1%)
Query: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 290
E F C C+ +L G + + D P+C CY F+ C C Q I H + + H+H
Sbjct: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
Query: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 348
F C C DE F ++ C + F+ +C C ++ + W
Sbjct: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
Query: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408
H CF+C C P SF +G C + + CA C +T V+ + +H
Sbjct: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
Query: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
+ CT C PL F R PYC CF +LF
Sbjct: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
Score = 40.0 bits (92), Expect = 0.004
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 211 CGSCNKPIAG----QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
C SC +PI G + V+ R WH F C CST+L G F C C
Sbjct: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 115 bits (287), Expect = 1e-25
Identities = 68/238 (28%), Positives = 102/238 (42%), Gaps = 12/238 (5%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRC 270
C C G+VV +H F C C L S FF K+ C + Y + + RC
Sbjct: 23 CYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRC 82
Query: 271 GFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF---------GDEGFHEREGRPYCRRDF 321
C I ++++ALG +HP+ F C C +PF G E + +
Sbjct: 83 DSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKP 142
Query: 322 LQLFAP-RCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
+++ P C GC+ I + AL WH CF C+ C + G + +G P CE+
Sbjct: 143 IKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILT-GEYISKDGVPYCESD 201
Query: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437
+HA+ G C TC ++GR + A G+ +HP C C + T+G G P
Sbjct: 202 YHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHP 259
Score = 88.6 bits (218), Expect = 1e-17
Identities = 56/187 (29%), Positives = 80/187 (42%), Gaps = 12/187 (6%)
Query: 269 RCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPR 328
+C C + ++V H+H F C CG GF + C +D+ QL+ R
Sbjct: 22 QCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTR 81
Query: 329 CQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRP-LCE---------N 378
C C+ I ISAL +HP CFVC C PF G G+ +C+
Sbjct: 82 CDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSK 141
Query: 379 HFHARRGSLCATCGLPVT-GRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437
R S CA C + G+ + AL +++H F C C LT G + + G PYC+
Sbjct: 142 PIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILT-GEYISKDGVPYCES 200
Query: 438 CFLKLFG 444
+ FG
Sbjct: 201 DYHAQFG 207
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 114 bits (284), Expect = 2e-25
Identities = 68/237 (28%), Positives = 100/237 (42%), Gaps = 11/237 (4%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRC 270
C C +P G+V+ + +H + F C C L FF K+G C Y + RC
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98
Query: 271 GFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHERE------GRPYCRRDF 321
C + + ++VTALG +HP F C C PF GD F+ R+ +P
Sbjct: 99 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158
Query: 322 LQLFAPRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHF 380
F+ C GC I + + AL WH CF C+ C + G + +G P CE +
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 217
Query: 381 HARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437
G C C +TG+ + A + +HP C+ C + T+G G P
Sbjct: 218 QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHP 274
Score = 98.6 bits (244), Expect = 1e-20
Identities = 54/185 (29%), Positives = 84/185 (45%), Gaps = 11/185 (5%)
Query: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 329
C C +P + +++ H+H + F C CG GF + G C D+ +++ RC
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98
Query: 330 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGR---------PLCENHF 380
GC + ++AL +HP+CF C C PF G GR P+ +
Sbjct: 99 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158
Query: 381 HARRGSLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
S CA CG + G+ + AL +++H F C C + LT G + + G PYC+ +
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 217
Query: 440 LKLFG 444
LFG
Sbjct: 218 QGLFG 222
Score = 75.1 bits (183), Expect = 1e-13
Identities = 49/180 (27%), Positives = 70/180 (38%), Gaps = 39/180 (21%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCS---------TALGGSSFFEKDGAPFCPEC 261
C C + + G+VVTALG+ +HP F C C T G + P
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157
Query: 262 YFERFSPRCGFCNQPIRH-KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRD 320
FS C C + I++ + + AL WH F C SCG+ E + ++G PYC +D
Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 216
Query: 321 FLQLFAPRCQGCQGPILDNYISAL----------------------------SALWHPDC 352
+ LF +C+ C I + A S +WHPDC
Sbjct: 217 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDC 276
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 114 bits (284), Expect = 2e-25
Identities = 68/237 (28%), Positives = 100/237 (42%), Gaps = 11/237 (4%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRC 270
C C +P G+V+ + +H + F C C L FF K+G C Y + RC
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98
Query: 271 GFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHERE------GRPYCRRDF 321
C + + ++VTALG +HP F C C PF GD F+ R+ +P
Sbjct: 99 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158
Query: 322 LQLFAPRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHF 380
F+ C GC I + + AL WH CF C+ C + G + +G P CE +
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 217
Query: 381 HARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437
G C C +TG+ + A + +HP C+ C + T+G G P
Sbjct: 218 QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHP 274
Score = 98.6 bits (244), Expect = 1e-20
Identities = 54/185 (29%), Positives = 84/185 (45%), Gaps = 11/185 (5%)
Query: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 329
C C +P + +++ H+H + F C CG GF + G C D+ +++ RC
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98
Query: 330 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGR---------PLCENHF 380
GC + ++AL +HP+CF C C PF G GR P+ +
Sbjct: 99 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158
Query: 381 HARRGSLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
S CA CG + G+ + AL +++H F C C + LT G + + G PYC+ +
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 217
Query: 440 LKLFG 444
LFG
Sbjct: 218 QGLFG 222
Score = 75.1 bits (183), Expect = 1e-13
Identities = 49/180 (27%), Positives = 70/180 (38%), Gaps = 39/180 (21%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCS---------TALGGSSFFEKDGAPFCPEC 261
C C + + G+VVTALG+ +HP F C C T G + P
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157
Query: 262 YFERFSPRCGFCNQPIRH-KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRD 320
FS C C + I++ + + AL WH F C SCG+ E + ++G PYC +D
Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 216
Query: 321 FLQLFAPRCQGCQGPILDNYISAL----------------------------SALWHPDC 352
+ LF +C+ C I + A S +WHPDC
Sbjct: 217 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDC 276
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 114 bits (284), Expect = 2e-25
Identities = 68/237 (28%), Positives = 100/237 (42%), Gaps = 11/237 (4%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRC 270
C C +P G+V+ + +H + F C C L FF K+G C Y + RC
Sbjct: 99 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 158
Query: 271 GFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHERE------GRPYCRRDF 321
C + + ++VTALG +HP F C C PF GD F+ R+ +P
Sbjct: 159 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 218
Query: 322 LQLFAPRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHF 380
F+ C GC I + + AL WH CF C+ C + G + +G P CE +
Sbjct: 219 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 277
Query: 381 HARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437
G C C +TG+ + A + +HP C+ C + T+G G P
Sbjct: 278 QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHP 334
Score = 98.6 bits (244), Expect = 1e-20
Identities = 54/185 (29%), Positives = 84/185 (45%), Gaps = 11/185 (5%)
Query: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 329
C C +P + +++ H+H + F C CG GF + G C D+ +++ RC
Sbjct: 99 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 158
Query: 330 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGR---------PLCENHF 380
GC + ++AL +HP+CF C C PF G GR P+ +
Sbjct: 159 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 218
Query: 381 HARRGSLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
S CA CG + G+ + AL +++H F C C + LT G + + G PYC+ +
Sbjct: 219 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 277
Query: 440 LKLFG 444
LFG
Sbjct: 278 QGLFG 282
Score = 75.1 bits (183), Expect = 1e-13
Identities = 49/180 (27%), Positives = 70/180 (38%), Gaps = 39/180 (21%)
Query: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCS---------TALGGSSFFEKDGAPFCPEC 261
C C + + G+VVTALG+ +HP F C C T G + P
Sbjct: 158 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 217
Query: 262 YFERFSPRCGFCNQPIRH-KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRD 320
FS C C + I++ + + AL WH F C SCG+ E + ++G PYC +D
Sbjct: 218 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 276
Query: 321 FLQLFAPRCQGCQGPILDNYISAL----------------------------SALWHPDC 352
+ LF +C+ C I + A S +WHPDC
Sbjct: 277 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDC 336
>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
Length = 276
Score = 112 bits (281), Expect = 5e-25
Identities = 55/158 (34%), Positives = 81/158 (51%), Gaps = 10/158 (6%)
Query: 210 LCGSCNKPIAGQ--VVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 267
+C C+K ++ + V A+ R +H + F C C L G SF++KDG P C CY +
Sbjct: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 144
Query: 268 PRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLFA 326
RCG C + +R ++ ALG +HP F CV+C GDE F + YC DF + FA
Sbjct: 145 -RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
Query: 327 PRCQGCQGPILDN------YISALSALWHPDCFVCREC 358
P C C+ PI+ I + +H +C+ C +C
Sbjct: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDC 241
Score = 83.6 bits (205), Expect = 3e-16
Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 270 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
C FC++ + R V A+ +H + F C +C + F++++GRP C + Q
Sbjct: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 144
Query: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 386
RC C + D+ I AL +HP CF C C SF + C + F+ +
Sbjct: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
Query: 387 LCATCGLPVTGR------CVSALGRRFHPDHFTCTFC-----LRPLTKGSFQERAGKPYC 435
+C+ C P+ R + +GR FH + + C C + P +G + +C
Sbjct: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLN-NHLFC 263
Query: 436 QPCFLK 441
+PC +K
Sbjct: 264 KPCHVK 269
Score = 71.6 bits (174), Expect = 1e-12
Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 341 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 400
+ A+ +H CF CR C +G SF++ +GRPLCE + C CG V +
Sbjct: 100 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 158
Query: 401 SALGRRFHPDHFTCTFCLRPLTKGSFQ-ERAGKPYCQPCFLKLF 443
ALG+ FHP FTC C R + SF + YC F + F
Sbjct: 159 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
Score = 51.6 bits (122), Expect = 1e-06
Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Query: 385 GSLCATCGLPVTGR--CVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
G +CA C V+ R V A+ R++H FTC C R L SF ++ G+P C+PC+
Sbjct: 83 GDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY 139
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 112 bits (281), Expect = 5e-25
Identities = 64/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)
Query: 211 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
C C KPI + R WH F C C+ +L F KD C ECY S
Sbjct: 41 CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
Query: 269 RCGFCNQPIR--HKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+C C + I + + G +WH F C +C +P G + +E YC F + FA
Sbjct: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
C C+ I I+ LWH +CF+C C F + P C + ++ +
Sbjct: 161 HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYAN 220
Query: 387 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
C C P++G + + ++H + F C C L F + + +CQ C
Sbjct: 221 KCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
Score = 103 bits (258), Expect = 2e-22
Identities = 56/214 (26%), Positives = 85/214 (39%), Gaps = 4/214 (1%)
Query: 234 HFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWHP 291
HF C C+ +L G + KD +P+C CY FS C C +PI K + HWH
Sbjct: 5 HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
Query: 292 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALWH 349
F C C ++ F ++ R C + + +C C+ I+ + WH
Sbjct: 65 GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
Query: 350 PDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHP 409
CFVC C P E C F C C +T ++ + +H
Sbjct: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
Query: 410 DHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
+ F C+ C + L + F R P+C C+ L+
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 112 bits (279), Expect = 9e-25
Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)
Query: 211 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
C C KPI ++ R WH F C C +L F K+ C +CY +S
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
Query: 269 RCGFCNQPIRH--KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+C C + I + + G+ WH F C C +P G + F ++ + +C + + A
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
+C C+ PI ++ WH +CFVC C SG F + C N F
Sbjct: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
Query: 387 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
CA C P++G + +S R++H D F C C L F C C
Sbjct: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 108 bits (269), Expect = 1e-23
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 4/215 (1%)
Query: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 290
E F C C+ +L G + ++ +P+C C+ F+ C C +PI K ++ HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY--ISALSALW 348
F C C D+ F +E + C + ++ +CQ C+ I+ + + W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408
H CF+C C P SF + + C + + C C P+T V+ + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
Query: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
+ F CT C + L+ F R YC CF L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
Score = 35.0 bits (79), Expect = 0.14
Identities = 22/103 (21%), Positives = 36/103 (34%), Gaps = 30/103 (29%)
Query: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269
+C +C K ++GQ TA +D +C C+ + ++ +
Sbjct: 187 VCTACRKQLSGQRFTA--------------------------RDDFAYCLNCFCDLYAKK 220
Query: 270 CGFCNQPIR----HKMVTALGTHWHPEHFCCVSCGEPFGDEGF 308
C C PI K ++ WH + F C C GF
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGF 263
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 112 bits (279), Expect = 9e-25
Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)
Query: 211 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
C C KPI ++ R WH F C C +L F K+ C +CY +S
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
Query: 269 RCGFCNQPIRH--KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
+C C + I + + G+ WH F C C +P G + F ++ + +C + + A
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Query: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
+C C+ PI ++ WH +CFVC C SG F + C N F
Sbjct: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
Query: 387 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
CA C P++G + +S R++H D F C C L F C C
Sbjct: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 108 bits (269), Expect = 1e-23
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 4/215 (1%)
Query: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 290
E F C C+ +L G + ++ +P+C C+ F+ C C +PI K ++ HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY--ISALSALW 348
F C C D+ F +E + C + ++ +CQ C+ I+ + + W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408
H CF+C C P SF + + C + + C C P+T V+ + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
Query: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
+ F CT C + L+ F R YC CF L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
Score = 35.0 bits (79), Expect = 0.14
Identities = 22/103 (21%), Positives = 36/103 (34%), Gaps = 30/103 (29%)
Query: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269
+C +C K ++GQ TA +D +C C+ + ++ +
Sbjct: 187 VCTACRKQLSGQRFTA--------------------------RDDFAYCLNCFCDLYAKK 220
Query: 270 CGFCNQPIR----HKMVTALGTHWHPEHFCCVSCGEPFGDEGF 308
C C PI K ++ WH + F C C GF
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGF 263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,009,210
Number of Sequences: 37866
Number of extensions: 1321029
Number of successful extensions: 10312
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 486
Number of HSP's that attempted gapping in prelim test: 8402
Number of HSP's gapped (non-prelim): 1861
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.