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Search of human proteins with 21327715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21327715 transcription elongation regulator 1 isoform 1
[Homo sapiens]
(1098 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 2202 0.0
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 2149 0.0
gi|148727264 transcription elongation regulator 1-like [Homo sap... 274 3e-73
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 132 1e-30
gi|151301228 formin binding protein 3 [Homo sapiens] 125 2e-28
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 111 3e-24
gi|148746195 trichohyalin [Homo sapiens] 99 2e-20
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 93 1e-18
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 84 7e-16
gi|7706501 WW domain binding protein 11 [Homo sapiens] 84 7e-16
gi|160707881 formin 2 [Homo sapiens] 84 1e-15
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 83 1e-15
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 80 8e-15
gi|11386183 WAS protein family, member 2 [Homo sapiens] 80 8e-15
gi|157168329 formin 1 [Homo sapiens] 78 5e-14
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 78 5e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni... 78 5e-14
gi|210032580 SET domain containing 1B [Homo sapiens] 77 7e-14
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 77 9e-14
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 1e-13
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 76 2e-13
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 76 2e-13
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 76 2e-13
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 76 2e-13
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens] 76 2e-13
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 75 3e-13
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 74 6e-13
gi|38788274 bromodomain PHD finger transcription factor isoform ... 74 8e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 74 8e-13
gi|150378539 piccolo isoform 1 [Homo sapiens] 74 8e-13
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 2202 bits (5705), Expect = 0.0
Identities = 1098/1098 (100%), Positives = 1098/1098 (100%)
Query: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP
Sbjct: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
Query: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP
Sbjct: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
Query: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ
Sbjct: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
Query: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ
Sbjct: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
Query: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT
Sbjct: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
Query: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP
Sbjct: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
Query: 361 VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIA 420
VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIA
Sbjct: 361 VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIA 420
Query: 421 ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP 480
ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP
Sbjct: 421 ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP 480
Query: 481 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG 540
SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG
Sbjct: 481 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG 540
Query: 541 DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW 600
DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW
Sbjct: 541 DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW 600
Query: 601 QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE 660
QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE
Sbjct: 601 QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE 660
Query: 661 ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE 720
ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE
Sbjct: 661 ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE 720
Query: 721 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA 780
KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA
Sbjct: 721 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA 780
Query: 781 RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 840
RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF
Sbjct: 781 RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 840
Query: 841 KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 900
KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI
Sbjct: 841 KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 900
Query: 901 QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 960
QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH
Sbjct: 901 QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 960
Query: 961 FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR 1020
FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR
Sbjct: 961 FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR 1020
Query: 1021 TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR 1080
TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR
Sbjct: 1021 TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR 1080
Query: 1081 RGPPPPPTASEPTRRSTK 1098
RGPPPPPTASEPTRRSTK
Sbjct: 1081 RGPPPPPTASEPTRRSTK 1098
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 2149 bits (5567), Expect = 0.0
Identities = 1077/1098 (98%), Positives = 1077/1098 (98%), Gaps = 21/1098 (1%)
Query: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP
Sbjct: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
Query: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP
Sbjct: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
Query: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ
Sbjct: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
Query: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ
Sbjct: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
Query: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT
Sbjct: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
Query: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP
Sbjct: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
Query: 361 VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIA 420
VMVPPFRVPLPGMPIPLPGV LPGMAPPIVPMIHPQVAIA
Sbjct: 361 VMVPPFRVPLPGMPIPLPGV---------------------LPGMAPPIVPMIHPQVAIA 399
Query: 421 ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP 480
ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP
Sbjct: 400 ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP 459
Query: 481 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG 540
SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG
Sbjct: 460 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG 519
Query: 541 DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW 600
DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW
Sbjct: 520 DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW 579
Query: 601 QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE 660
QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE
Sbjct: 580 QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE 639
Query: 661 ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE 720
ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE
Sbjct: 640 ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE 699
Query: 721 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA 780
KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA
Sbjct: 700 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA 759
Query: 781 RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 840
RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF
Sbjct: 760 RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 819
Query: 841 KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 900
KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI
Sbjct: 820 KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 879
Query: 901 QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 960
QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH
Sbjct: 880 QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 939
Query: 961 FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR 1020
FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR
Sbjct: 940 FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR 999
Query: 1021 TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR 1080
TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR
Sbjct: 1000 TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR 1059
Query: 1081 RGPPPPPTASEPTRRSTK 1098
RGPPPPPTASEPTRRSTK
Sbjct: 1060 RGPPPPPTASEPTRRSTK 1077
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 274 bits (701), Expect = 3e-73
Identities = 128/274 (46%), Positives = 188/274 (68%), Gaps = 20/274 (7%)
Query: 514 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 573
E+ A+ +PVA+ P+PG+PWCVVWTGD+RVFF+NPT LS+W++P DL R D+++II+
Sbjct: 325 EDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDRGDLNRIIE 384
Query: 574 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 633
+PPHK+ +E + + + E+ ED+ VK K+ + +
Sbjct: 385 DPPHKRKLE--------------------APATDNSDGSSSEDNREDQDVKTKRNRTEGC 424
Query: 634 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 693
E+ + + + ++PLE R+ F+DMLLERGVSAFSTWEKELHKIVFDPR
Sbjct: 425 GSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIVFDPR 484
Query: 694 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 753
YLLLN +ERKQ+F+Q+VKTR +EE +EKK+K++ AKE+FKK++EE+K +PR TF EFA K
Sbjct: 485 YLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKEFAEK 544
Query: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKED 787
+ +D RF+ ++K KD+E FN+F+ +K++KE+
Sbjct: 545 YGRDQRFRLVQKRKDQEHFFNQFILILKKRDKEN 578
Score = 59.7 bits (143), Expect = 1e-08
Identities = 100/462 (21%), Positives = 178/462 (38%), Gaps = 126/462 (27%)
Query: 317 VSVSTPAPTATPVQTV---PQPHPQ--------TLPPAV--------------PHSV--P 349
VS+S PAP + P+ TV PQP P T PA+ P ++ P
Sbjct: 200 VSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGP 259
Query: 350 QPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVAT-TKTGVLPGMAPP 408
P++ P + + P ++PL P+ ++ P + A ++ G PP
Sbjct: 260 SPSSVQPRHF-LTLAPIKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPP 318
Query: 409 IVPMIHPQVAIAASPATLAGATAV--SEWTEYKTADGKTYYYNNRTLESTWEKPQELKEK 466
PM+ A +T V S W T D + +++N S WEKP +LK++
Sbjct: 319 --PMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDR 376
Query: 467 EKLEEKIKEP-----IKEPSEEPLPMETEEEDPKEEPIKEIKE------EPKEEEMTEEE 515
L I++P ++ P+ + + E++ +++ +K + PK EE E+
Sbjct: 377 GDLNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNRTEGCGSPKPEEAKRED 436
Query: 516 KAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNP------TTRLSMWDRPDDLIGRADVD 569
K + P P+ +ERV + + S W++ ++
Sbjct: 437 KGTRTPPPQILLPL-----------EERVTHFRDMLLERGVSAFSTWEK--------ELH 477
Query: 570 KIIQEPPH-KKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKR 628
KI+ +P + EE K++ QF + IKEE K KK
Sbjct: 478 KIVFDPRYLLLNSEERKQIFE-----------QFVKTRIKEE------------YKEKKS 514
Query: 629 KRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKI 688
K L ++FK +L E VS +T+++ K
Sbjct: 515 K-----------------------------LLLAKEEFKKLLEESKVSPRTTFKEFAEKY 545
Query: 689 VFDPRYLLLNP-KERKQVFDQYVKTRAEEERREKKNKIMQAK 729
D R+ L+ K+++ F+Q++ ++R+K+N++ K
Sbjct: 546 GRDQRFRLVQKRKDQEHFFNQFILIL---KKRDKENRLRLRK 584
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/205 (27%), Positives = 77/205 (37%), Gaps = 41/205 (20%)
Query: 20 RMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPF--------GMMR---GPPPPPRPPFG 68
R QQQ R R P P M PP PPPP+ G++R G PP
Sbjct: 12 RQLQQQQPRRRQPLLWP---MDAEPP---PPPPWVWMVPGSAGLLRLSAGVVVPPVLLAS 65
Query: 69 RPPFDPNMPPMPPPGGIPPPMGP--PHLQRP--PFMPPPMSSMPPP------------PG 112
PP P P +P G P P P P L P P ++ P P P
Sbjct: 66 APP--PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPS 123
Query: 113 MMFPPGMPPVTAPGTPALPPTE------EIWVENKTPDGKVYYYNARTRESAWTKPDGVK 166
+ PP P P L P+ + W++ + P+ K+++ N+ +S W P+ +
Sbjct: 124 LGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESR 183
Query: 167 VIQQSELTPMLAAQAQVQAQAQAQA 191
E +LA Q V A A
Sbjct: 184 FFHGHEKPRLLANQVAVSLSRPAPA 208
Score = 41.2 bits (95), Expect = 0.005
Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 15/103 (14%)
Query: 960 HFRQLLDETSAITLTSTW-KEVKKIIKEDPRCIKFSSSDRK-------KQREFEEY--IR 1009
HFR +L E ++ STW KE+ KI+ DPR + +S +RK K R EEY +
Sbjct: 456 HFRDMLLERG-VSAFSTWEKELHKIVF-DPRYLLLNSEERKQIFEQFVKTRIKEEYKEKK 513
Query: 1010 DKYITAKADFRTLLKETKFITYRSKKLIQES---DQHLKDVEK 1049
K + AK +F+ LL+E+K + K E DQ + V+K
Sbjct: 514 SKLLLAKEEFKKLLEESKVSPRTTFKEFAEKYGRDQRFRLVQK 556
Score = 39.3 bits (90), Expect = 0.021
Identities = 57/283 (20%), Positives = 110/283 (38%), Gaps = 69/283 (24%)
Query: 691 DPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEF 750
D R NP V+++ + + R N+I++ +K+ A N + SE
Sbjct: 352 DDRVFFFNPTMHLSVWEKPMDLKD----RGDLNRIIEDPPHKRKLEAPATDNSDGSSSED 407
Query: 751 AAKH----AKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRG---------EKIKS 797
+ K +R + K EA ++ED TR E+ +
Sbjct: 408 NREDQDVKTKRNRTEGCGSPKPEEA------------KREDKGTRTPPPQILLPLEERVT 455
Query: 798 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 857
F ++L + + S W K K+ DPRY ++S R+ +F+Q++
Sbjct: 456 HFRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNSEE-RKQIFEQFV------------- 501
Query: 858 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS 917
+ RI+ +E++ ++ A+ E FK LL + S +
Sbjct: 502 ----KTRIKEEYKEKKSKLLLAKEE--------------------FKKLLEESKVSPRTT 537
Query: 918 WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 960
+ + +D R+ + +R+++E FN+ I L K+ +E+
Sbjct: 538 FKEFAEKYGRDQRFR--LVQKRKDQEHFFNQFILILKKRDKEN 578
>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sapiens]
Length = 871
Score = 132 bits (333), Expect = 1e-30
Identities = 176/733 (24%), Positives = 293/733 (39%), Gaps = 138/733 (18%)
Query: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV--AMMQIVSCPYVK 392
P P PP +P P FPP+ +PP P +P PG+ M+ + P
Sbjct: 3 PPPFMPPPGIP----------PPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPL 52
Query: 393 TVATTKTGVLPGMAPPIVP-MIHPQVAIAASPATLAGATAVSE-----------WTEYKT 440
T +PGM PP++P M+ P V + A AT GA S W+E+
Sbjct: 53 T-------QIPGMVPPMMPGMLMPAVPVTA--ATAPGADTASSAVAGTGPPRALWSEHVA 103
Query: 441 ADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIK 500
DG+ YYYN +S WEKP LK K +L + P KE + KE
Sbjct: 104 PDGRIYYYNADDKQSVWEKPSVLKSKAELLLS-QCPWKEYKSDTGKPYYYNNQSKESRWT 162
Query: 501 EIKEEPKEEEMTEEEKAA--QKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDR 558
K+ E + ++E A Q+ P P P P D
Sbjct: 163 RPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQP---------------------QPDP 201
Query: 559 PDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEIN 618
P G V + E P G E+ L P EQ ++++
Sbjct: 202 PPVPPGPTPVPTGLLE-PEPGGSEDCDVLEATQPL----------------EQGFLQQLE 244
Query: 619 EDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAF 678
E + + + + + +S+ E + RE+A + FK++L ++ V +
Sbjct: 245 EGPSSSGQHQPQQEEE--ESKPEPERSGLSWSNREKA-------KQAFKELLRDKAVPSN 295
Query: 679 STWEKELHKIVFDPRYLLLNPK--ERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMM 736
++WE+ + +V DPRY L PK E+KQ F+ Y R +EE+ E + + +AK+ + +
Sbjct: 296 ASWEQAMKMVVTDPRYSAL-PKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFL 354
Query: 737 EEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSK-TRGEKI 795
E+ + T A + + A+ +DR+ ++++ + KKEKE +K R I
Sbjct: 355 EQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNI 414
Query: 796 KSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI--EKIAKNLDS 853
++ L ++ Q+ WS+ + + +P + A D D I E+ + L+
Sbjct: 415 QALKSILDGMSSVNFQTTWSQAQQYLMDNPSF-AQDHQLQNMDKEDALICFEEHIRALER 473
Query: 854 EKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRS 913
E+E+E ER A LRER R+Q K EA Q F L + +
Sbjct: 474 EEEEERER-----ARLRER------------------RQQRKNREAFQTFLDELHETGQL 510
Query: 914 SDVS-WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQ------LLD 966
+S W + + D R+ + LF ++E L K R H + L D
Sbjct: 511 HSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEEL--KARFHDEKKIIKDILKD 568
Query: 967 ETSAITLTSTWKEVKKIIKEDPRCIKFSSSD--------------RKKQREFEEYIRDKY 1012
+ + + +++ +I D R + + R+++RE EE R +
Sbjct: 569 RGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMR- 627
Query: 1013 ITAKADFRTLLKE 1025
+A FR++L++
Sbjct: 628 -RREAAFRSMLRQ 639
Score = 92.0 bits (227), Expect = 3e-18
Identities = 57/138 (41%), Positives = 68/138 (49%), Gaps = 27/138 (19%)
Query: 43 PPPLMRPP---PPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPP 98
PPP M PP PPF M PP RPP PP P +PPM PP G PPP+ Q P
Sbjct: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPG 57
Query: 99 FMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVY 148
+PP M PGM+ P PVTA P P +W E+ PDG++Y
Sbjct: 58 MVPPMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIY 109
Query: 149 YYNARTRESAWTKPDGVK 166
YYNA ++S W KP +K
Sbjct: 110 YYNADDKQSVWEKPSVLK 127
Score = 74.3 bits (181), Expect = 6e-13
Identities = 108/577 (18%), Positives = 218/577 (37%), Gaps = 107/577 (18%)
Query: 524 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 583
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 88 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 145
Query: 584 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 633
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 146 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 205
Query: 634 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 693
+E E + + ++ ++Q LE G S+ + +
Sbjct: 206 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 256
Query: 694 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 753
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 257 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 304
Query: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 813
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 305 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 357
Query: 814 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 873
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 358 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 402
Query: 874 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 932
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 403 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 447
Query: 933 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 968
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 448 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 507
Query: 969 SAITLTSTWKEVKKIIKEDPRCIKF----SSSDRKKQREFEEYIRDKYITAKADFRTLLK 1024
+ STW E+ + D R S+ + + E ++ ++ K + +LK
Sbjct: 508 GQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILK 567
Query: 1025 ETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1061
+ F E + +D ++ DKR LD
Sbjct: 568 DRGFCV--------EVNTAFEDFAHVISFDKRAAALD 596
Score = 53.9 bits (128), Expect = 8e-07
Identities = 112/553 (20%), Positives = 210/553 (37%), Gaps = 96/553 (17%)
Query: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGVAMMQIVSCPYVK 392
Q PQTL P P P P PPV PP P+P G+ P PG + C ++
Sbjct: 184 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSE----DCDVLE 230
Query: 393 TVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYN 449
+ G L + P++ E E K G ++
Sbjct: 231 ATQPLEQGFLQ--------------QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNR 276
Query: 450 NRTLESTWE--KPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK 507
+ ++ E + + + E+ +K + +P LP +E K++ K + +
Sbjct: 277 EKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQRE 332
Query: 508 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 567
+EE E A++AK T + + T + + R + G +
Sbjct: 333 KEEKEEARLRAKEAKQ---------------TLQHFLEQHERMTSTTRYRRAEQTFGELE 377
Query: 568 VDKIIQEPPHK------------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEE 610
V ++ E K K E+ K+LR L + F + + +
Sbjct: 378 VWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQ 437
Query: 611 QELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ----- 665
Q LM+ + + + + ++D E A+E E + RERA + + ++
Sbjct: 438 QYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAF 497
Query: 666 --FKDMLLERG-VSAFSTWEKELHKIVFDPRY--LLLNPKERK-QVFDQYVKTRAEEERR 719
F D L E G + + STW + + D R+ +L P +F YV+
Sbjct: 498 QTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVE-------- 549
Query: 720 EKKNKIMQAKEDFKKMMEEAKF--NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFV 777
E K + K+ K ++++ F F +FA + D R A++ + + FN +
Sbjct: 550 ELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDA-GNIKLTFNSLL 608
Query: 778 --AAARKKEKEDSKTRGEKIKSDFFELLSNHH---LDSQSRWSKVKDKVESDPRYKAVDS 832
A AR++E+E + R + + F + L+ + W +V+++ D ++ +
Sbjct: 609 EKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 668
Query: 833 SSMREDLFKQYIE 845
S R LF+++++
Sbjct: 669 ESERIRLFREFLQ 681
Score = 47.4 bits (111), Expect = 8e-05
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 664 KQFKDMLLERG--VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERRE 720
K KD+L +RG V + +E H I FD R L+ K F+ + K A E RE
Sbjct: 560 KIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARERERE 619
Query: 721 KKN--KIMQAKEDFKKMMEEA--KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 776
K+ ++ + + F+ M+ +A + E + DS F+ I +R LF EF
Sbjct: 620 KEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREF 679
Query: 777 VAAARKKEKEDSKTRGEK 794
+ + E + T+G K
Sbjct: 680 LQVLEQTECQHLHTKGRK 697
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 125 bits (315), Expect = 2e-28
Identities = 181/778 (23%), Positives = 313/778 (40%), Gaps = 121/778 (15%)
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPL 370
S +PT+ T A + P H P H + Q +P P M+P P+
Sbjct: 10 SSLSPTMRPGTGAERGGLMMGHPGMH---YAPMGMHPMGQRAN-MPPVPHGMMPQMMPPM 65
Query: 371 PGMPI-PLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGA 429
G P+ +PG MM V P + ++ + P + P + M +AA A+
Sbjct: 66 GGPPMGQMPG--MMSSVM-PGMMMSHMSQASMQPALPPGVNSM-----DVAAGTAS---- 113
Query: 430 TAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEK-EKLEEKIK-EPIKEPSEEPLPM 487
A S WTE+K+ DG+TYYYN T +STWEKP +LK E+L K + K S +P
Sbjct: 114 GAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYY 173
Query: 488 ETEEEDPKEEPIKEIKEEP----------------------KEEEMTEEEKAAQKAKPVA 525
++ ++ + KE+++ EE +EE PV
Sbjct: 174 NSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVP 233
Query: 526 TAPIPGT---------PWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP 576
T IP T VV + + + G V + EP
Sbjct: 234 TTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPV---VPEPE 290
Query: 577 HKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDI 636
+ + + T T+ + ++ Q + + ++Q + N E K++ D
Sbjct: 291 VTSIVATVVDNEN-TVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETS----KQETVADF 345
Query: 637 DSEKEAAMEAEIKAARERAIVPLEARMKQ-FKDMLLERGVSAFSTWEKELHKIVFDPRY- 694
+KE E E + A++ + KQ FK++L E+ V + ++WE+ + I+ DPRY
Sbjct: 346 TPKKE---EEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYS 402
Query: 695 LLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMME-EAKFNPRATFSEFAAK 753
L E+KQ F+ Y +EE+ E ++K +AKE F++ +E K + +
Sbjct: 403 ALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQM 462
Query: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQS 812
+ + AI + +DR ++ + + KKEKE +K ++ +L N ++ +
Sbjct: 463 FGEMEVWNAISE-RDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYST 521
Query: 813 RWSKVKDKVESDPRYKAVDSSSMRED------LFKQYIEKIAKNLDSEKEKELERQARIE 866
WS+ + + +P + A D D F+++I + K + EK+K L
Sbjct: 522 TWSEAQQYLMDNPTF-AEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL------- 573
Query: 867 ASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTL 925
LRER R Q K E+ Q F L + + S SW + T+
Sbjct: 574 --LRER------------------RRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTI 613
Query: 926 RKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQ------LLDETSAITLTSTWKE 979
D R+ + LF ++E L K R H + L D+ + + +T+++
Sbjct: 614 SSDIRFTNMLGQPGSTALDLFKFYVEDL--KARYHDEKKIIKDILKDKGFVVEVNTTFED 671
Query: 980 VKKIIKEDPRCIKFSSSDRK------------KQREFEEYIRDKYITAKADFRTLLKE 1025
II R + + K ++RE E+ K ++ F+++LK+
Sbjct: 672 FVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQ 729
Score = 117 bits (292), Expect = 8e-26
Identities = 190/971 (19%), Positives = 354/971 (36%), Gaps = 183/971 (18%)
Query: 45 PLMRPPPPF---GMMRGPPPPPRPPFGRPPFDP--NMPPMPP---PGGIPPPMGPPHLQR 96
P MRP G+M G P P G P NMPP+P P +PP GPP Q
Sbjct: 14 PTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQM 73
Query: 97 PPFMPPPMSSMPPPPGMMFP----PGMPPVTAPGTPALPPT-------EEIWVENKTPDG 145
P M M PGMM M P PG ++ + +W E+K+PDG
Sbjct: 74 PGMMSSVM------PGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDG 127
Query: 146 KVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
+ YYYN T++S W KPD +K + L+ + + + +Q + A+ +
Sbjct: 128 RTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKE 187
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ ++ A +A+ ++ + T T+++
Sbjct: 188 LEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEE-----------------CTTTSTA 230
Query: 266 PAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPT 325
P P T+ ST ++ + + A ++A + A S S
Sbjct: 231 PVPTTEIPTTMSTMAAAEAAAAVVAAAAAA-----------AAAAAAANANASTSASNTV 279
Query: 326 ATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQI 385
+ V VP+P ++ V V T + + Q+
Sbjct: 280 SGTVPVVPEPEVTSIVATV---VDNENT---------------------VTISTEEQAQL 315
Query: 386 VSCPYVKTVA---TTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTAD 442
S P ++ + ++ TG + T+A T E E + A
Sbjct: 316 TSTPAIQDQSVEVSSNTG-----------------EETSKQETVADFTPKKEEEESQPAK 358
Query: 443 GKTYYYNNRTLESTWEKPQELKE--KEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIK 500
KTY TW +E K+ KE L+EK + P E+ + M DP+ +
Sbjct: 359 -KTY---------TWNTKEEAKQAFKELLKEK-RVPSNASWEQAMKMIIN--DPRYSALA 405
Query: 501 EIKEEPK-------EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRL 553
++ E+ + + E E+E+A K K + + + T
Sbjct: 406 KLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKES------------FQRFLENHEKMTST 453
Query: 554 SMWDRPDDLIGRADVDKIIQEPPH------------KKGMEELKKLRHP----------- 590
+ + + + + G +V I E KK E+ K+LR
Sbjct: 454 TRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDN 513
Query: 591 ------TPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAM 644
+ T Q++ E++EL ED + ++ R K+ + EK+ ++
Sbjct: 514 MANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL 573
Query: 645 EAEIKAARERAIVPLEARMKQFKDMLLERG-VSAFSTWEKELHKIVFDPRYLLLNPKERK 703
E + R+ + F D L E G + + S+W + I D R+ + +
Sbjct: 574 LRERRRQRKN-----RESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGS 628
Query: 704 QVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKF--NPRATFSEFAAKHAKDSRFK 761
D + K E+ K + K+ K ++++ F TF +F A + R
Sbjct: 629 TALDLF-KFYVED----LKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRST 683
Query: 762 AIEKMKDREALFNEFV--AAARKKEKEDSKTRGEKIKSDFFELLSNHH---LDSQSRWSK 816
++ + A FN + A AR++E+E + R K K F+ + ++ + W
Sbjct: 684 TLDAGNIKLA-FNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWED 742
Query: 817 VKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREV 876
++++ +P ++ + S R+ +FK ++ + K + + + R+R R
Sbjct: 743 IRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSR 802
Query: 877 QKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRW---ES 933
+ S+ +++ Q + + ++ RS S +++ ++ H+ ES
Sbjct: 803 SGSDSDDDDSHSKKKRQRSESRSASEHSS-SAESERSYKKSKKHKKKSKKRRHKSDSPES 861
Query: 934 GSLLEREEKEK 944
+ E+++KEK
Sbjct: 862 DAEREKDKKEK 872
Score = 80.9 bits (198), Expect = 6e-15
Identities = 90/393 (22%), Positives = 166/393 (42%), Gaps = 76/393 (19%)
Query: 701 ERKQVFDQYVKTRAEEERREKK----NKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAK 756
+++ V D K EE + KK N +AK+ FK++++E + A++ +
Sbjct: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
Query: 757 DSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSK 816
D R+ A+ K+ +++ FN + K+EKE+++++ ++ K F L NH
Sbjct: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENH---------- 447
Query: 817 VKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREV 876
+K+ S RYK + + + E N SE+++ LE + L ++E+
Sbjct: 448 --EKMTSTTRYKKAE---------QMFGEMEVWNAISERDR-LEIYEDVLFFLSKKEK-- 493
Query: 877 QKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSL 936
EQ K++ + + EA++N ++++ S+ +WS+ ++ L + +
Sbjct: 494 -----EQAKQL-----RKRNWEALKNILDNMANVTYST--TWSEAQQYLMDNPTFAEDEE 541
Query: 937 LEREEKEK---LFNEHIEALTK------------------KKREHFRQLLDET---SAIT 972
L+ +KE F EHI AL K K RE F+ LDE +
Sbjct: 542 LQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLH 601
Query: 973 LTSTWKEVKKIIKEDPRCIKFSSSDRKKQRE-FEEYIRD---KYITAKADFRTLLKETKF 1028
S+W E+ I D R + F+ Y+ D +Y K + +LK+ F
Sbjct: 602 SMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGF 661
Query: 1029 ITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1061
+ E + +D I+ + KR LD
Sbjct: 662 VV--------EVNTTFEDFVAIISSTKRSTTLD 686
Score = 80.5 bits (197), Expect = 8e-15
Identities = 156/729 (21%), Positives = 275/729 (37%), Gaps = 125/729 (17%)
Query: 435 WTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDP 494
W EYK+ GK YYYN++T ES W KP+EL++ E + I M EE
Sbjct: 160 WKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESS 219
Query: 495 KEEPIKEIKEEP---KEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTT 551
K+E P E T AA +A A + T
Sbjct: 220 KQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTV 279
Query: 552 RLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKE-- 609
++ P+ + + E EE +L TP + Q + S + +E
Sbjct: 280 SGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTS-TPAIQD-QSVEVSSNTGEETS 337
Query: 610 EQELM------EEINEDEPVK------AKKRKRDDNKDIDSEK--------EAAMEAEIK 649
+QE + +E E +P K K+ + K++ EK E AM+ I
Sbjct: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
Query: 650 AARERAIVPLEARMKQFKDMLLE--------------RGVSAFSTWEKELHKIVFDPRYL 695
R A+ L + + F ++ +F + + K+ RY
Sbjct: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYK 457
Query: 696 -------------LLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEE-AKF 741
++ ++R ++++ + +++E+ + K + E K +++ A
Sbjct: 458 KAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANV 517
Query: 742 NPRATFSEFAAKHAKDSRFKA----IEKMKDREAL--FNEFVAAARKKEKEDS------- 788
T+SE A ++ D+ A ++ M +AL F E + A K+E+E+
Sbjct: 518 TYSTTWSE-AQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRE 576
Query: 789 KTRGEKIKSDFFELLSNHH----LDSQSRWSKVKDKVESDPRYKAV--DSSSMREDLFKQ 842
+ R K + F L H L S S W ++ + SD R+ + S DLFK
Sbjct: 577 RRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKF 636
Query: 843 YIE----------KIAKNLDSEKEKELERQARIE---ASLRERERE-------------- 875
Y+E KI K++ +K +E E A + +R
Sbjct: 637 YVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
Query: 876 -VQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR--SSDVSWSDTRRTLRKDHRWE 932
++KA + + + E + KR+E+ FK++L D W D R K+ +E
Sbjct: 697 LLEKAEAREREREKEEARKMKRKESA--FKSMLKQAAPPIELDAVWEDIRERFVKEPAFE 754
Query: 933 SGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIK 992
+L E++++F + + L + + H + + K+ KK ++ R
Sbjct: 755 DITL--ESERKRIFKDFMHVLEHECQHHHSKNKKHS---------KKSKKHHRKRSRSRS 803
Query: 993 FSSSD-----RKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDV 1047
S SD KK+R+ E ++ A+ K++K +SKK +SD D
Sbjct: 804 GSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA 863
Query: 1048 EKILQNDKR 1056
E+ + DK+
Sbjct: 864 ER--EKDKK 870
Score = 57.0 bits (136), Expect = 1e-07
Identities = 72/301 (23%), Positives = 122/301 (40%), Gaps = 35/301 (11%)
Query: 664 KQFKDMLLERG--VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERRE 720
K KD+L ++G V +T+E + I R L+ K F+ + K A E RE
Sbjct: 650 KIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEARERERE 709
Query: 721 KKN--KIMQAKEDFKKMMEEAK--FNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 776
K+ K+ + + FK M+++A A + + + K+ F+ I +R+ +F +F
Sbjct: 710 KEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDF 769
Query: 777 VAAARKK-EKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAV--DSS 833
+ + + SK + KS +H S+SR D +S + K +S
Sbjct: 770 MHVLEHECQHHHSKNKKHSKKSK-----KHHRKRSRSRSGSDSDDDDSHSKKKRQRSESR 824
Query: 834 SMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQ 893
S E E+ K K+K +R+ + ++ + ERE K ++ E DR R+
Sbjct: 825 SASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQ- 883
Query: 894 HKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWE-SGSLLEREEKEKLFNEHIEA 952
RS S ++T + W+ SGS L E EK +E
Sbjct: 884 ------------------RSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQ 925
Query: 953 L 953
L
Sbjct: 926 L 926
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sapiens]
Length = 858
Score = 111 bits (278), Expect = 3e-24
Identities = 167/745 (22%), Positives = 289/745 (38%), Gaps = 167/745 (22%)
Query: 328 PVQTVPQPHP-------QTLPPAVPHSVPQPTTAIPAF-PPVMVPPFRVPLPGMPIPL-P 378
P +P P P PPA+P P P +P PP+ PP +PGM P+ P
Sbjct: 2 PPPGIPPPFPPMGLPPMSQRPPAIP---PMPPGILPPMLPPMGAPPPLTQIPGMVPPMMP 58
Query: 379 GVAMMQIVSCPYVKTVATTKTGVLPGMAPP-------IVP-------MIHPQVAIAASPA 424
G+ M + A T + + G PP + P + ++ P+
Sbjct: 59 GMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPS 118
Query: 425 TLAGATAV----SEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP 480
L + W EYK+ GK YYYNN++ ES W +P++L + LE +K+
Sbjct: 119 VLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDL---DDLEVLVKQEAAGK 175
Query: 481 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG 540
++ LP + + P+ +P PV P P
Sbjct: 176 QQQQLPQTLQPQPPQPQP---------------------DPPPVPPGPTP---------- 204
Query: 541 DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW 600
PT L + G D D + P ++G + +++
Sbjct: 205 -------VPTGLLE-----PEPGGSEDCDVLEATQPLEQGF------------LQQLEEG 240
Query: 601 QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE 660
S + +QE EE ++ EP ++ S +E A +A + R++A VP
Sbjct: 241 PSSSGQHQPQQE--EEESKPEPERSGLSW--------SNREKAKQAFKELLRDKA-VPSN 289
Query: 661 ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPK--ERKQVFDQYVKTRAEEER 718
A +Q M +V DPRY L PK E+KQ F+ Y R +EE+
Sbjct: 290 ASWEQAMKM------------------VVTDPRYSAL-PKLSEKKQAFNAYKAQREKEEK 330
Query: 719 REKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVA 778
E + + +AK+ + +E+ + T A + + A+ +DR+ ++++ +
Sbjct: 331 EEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLF 390
Query: 779 AARKKEKEDSK-TRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMRE 837
KKEKE +K R I++ L ++ Q+ WS+ + + +P + A D
Sbjct: 391 FLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSF-AQDHQLQNM 449
Query: 838 DLFKQYI--EKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHK 895
D I E+ + L+ E+E+E ER A LRER R+Q K
Sbjct: 450 DKEDALICFEEHIRALEREEEEERER-----ARLRER------------------RQQRK 486
Query: 896 REEAIQNFKALLSDMVRSSDVS-WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALT 954
EA Q F L + + +S W + + D R+ + LF ++E L
Sbjct: 487 NREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELK 546
Query: 955 KKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSD--------------RKK 1000
+ + + + D + + + +++ +I D R + + R++
Sbjct: 547 ARFHDEKKIIKD---ILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARER 603
Query: 1001 QREFEEYIRDKYITAKADFRTLLKE 1025
+RE EE R + +A FR++L++
Sbjct: 604 EREKEEARRMR--RREAAFRSMLRQ 626
Score = 87.4 bits (215), Expect = 7e-17
Identities = 55/135 (40%), Positives = 67/135 (49%), Gaps = 26/135 (19%)
Query: 43 PPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPPFMP 101
PPP + PPPF M PP RPP PP P +PPM PP G PPP+ Q P +P
Sbjct: 2 PPPGI--PPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPGMVP 54
Query: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVYYYN 151
P M PGM+ P PVTA P P +W E+ PDG++YYYN
Sbjct: 55 PMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYN 106
Query: 152 ARTRESAWTKPDGVK 166
A ++S W KP +K
Sbjct: 107 ADDKQSVWEKPSVLK 121
Score = 73.2 bits (178), Expect = 1e-12
Identities = 109/576 (18%), Positives = 217/576 (37%), Gaps = 112/576 (19%)
Query: 524 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 583
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 82 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 139
Query: 584 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 633
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 140 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 199
Query: 634 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 693
+E E + + ++ ++Q LE G S+ + +
Sbjct: 200 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 250
Query: 694 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 753
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 251 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 298
Query: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 813
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 299 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 351
Query: 814 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 873
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 352 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 396
Query: 874 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 932
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 397 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 441
Query: 933 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 968
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 442 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 501
Query: 969 SAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKF 1028
+ STW E+ + D R F + T F+ ++E K
Sbjct: 502 GQLHSMSTWMELYPAVSTDVR--------------FANMLGQPGSTPLDLFKFYVEELKA 547
Query: 1029 ITYRSKKLIQE---SDQHLKDVEKILQNDKRYLVLD 1061
+ KK+I++ + +D ++ DKR LD
Sbjct: 548 RFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALD 583
Score = 72.4 bits (176), Expect = 2e-12
Identities = 55/173 (31%), Positives = 69/173 (39%), Gaps = 63/173 (36%)
Query: 59 PP--PPPRPPFGRPPFD---PNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM 113
PP PPP PP G PP P +PPMPP GI PPM PP PP P P PGM
Sbjct: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPP--GILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
Query: 114 MFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVYYYNA----------- 152
+ P PVTA P P +W E+ PDG++YYYNA
Sbjct: 61 LMPA--VPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPS 118
Query: 153 ------------------------------RTRESAWTKP---DGVKVIQQSE 172
+++ES WT+P D ++V+ + E
Sbjct: 119 VLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQE 171
Score = 54.3 bits (129), Expect = 6e-07
Identities = 113/553 (20%), Positives = 216/553 (39%), Gaps = 103/553 (18%)
Query: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGVAMMQIVSCPYVK 392
Q PQTL P P P P PPV PP P+P G+ P PG + C ++
Sbjct: 178 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSE----DCDVLE 224
Query: 393 TVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYN 449
+ G L + P++ E E K G ++
Sbjct: 225 ATQPLEQGFLQ--------------QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNR 270
Query: 450 NRTLESTWE--KPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK 507
+ ++ E + + + E+ +K + +P LP +E K++ K + +
Sbjct: 271 EKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQRE 326
Query: 508 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 567
+EE E A++AK T + + T + + R + G +
Sbjct: 327 KEEKEEARLRAKEAKQ---------------TLQHFLEQHERMTSTTRYRRAEQTFGELE 371
Query: 568 VDKIIQEPPHK------------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEE 610
V ++ E K K E+ K+LR L + F + + +
Sbjct: 372 VWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQ 431
Query: 611 QELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ----- 665
Q LM+ + + + + ++D E A+E E + RERA + + ++
Sbjct: 432 QYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAF 491
Query: 666 --FKDMLLERG-VSAFSTWEKELHKIVFDPRYLLL------NPKERKQVFDQYVKTRAEE 716
F D L E G + + STW + + D R+ + P + + + + +K R +
Sbjct: 492 QTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHD 551
Query: 717 ERREKKN--KIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFN 774
E++ K+ K+ A EDF ++ F+ RA + A + K + +EK + RE
Sbjct: 552 EKKIIKDILKVNTAFEDFAHVIS---FDKRAAALD--AGNIKLTFNSLLEKAEARE---- 602
Query: 775 EFVAAARKKEKEDSKTRGEKIKSDFFELLSNH--HLDSQSRWSKVKDKVESDPRYKAVDS 832
R++EKE+++ R + ++ F +L L+ + W +V+++ D ++ +
Sbjct: 603 ------REREKEEAR-RMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 655
Query: 833 SSMREDLFKQYIE 845
S R LF+++++
Sbjct: 656 ESERIRLFREFLQ 668
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Query: 679 STWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERREKKN--KIMQAKEDFKKM 735
+ +E H I FD R L+ K F+ + K A E REK+ ++ + + F+ M
Sbjct: 564 TAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSM 623
Query: 736 MEEA--KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGE 793
+ +A + E + DS F+ I +R LF EF+ + E + T+G
Sbjct: 624 LRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGR 683
Query: 794 K 794
K
Sbjct: 684 K 684
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 99.4 bits (246), Expect = 2e-20
Identities = 130/626 (20%), Positives = 283/626 (45%), Gaps = 104/626 (16%)
Query: 458 EKPQELKEKEKLEEKIKEPIK----EPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTE 513
E+ Q+L + E+ EE+ ++ ++ E E+ L E EEE ++ +E +EE +E+E+ E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 514 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 573
EE+ ++A+ + IP W + D R + ++ RP Q
Sbjct: 688 EEQ--EQARERIKSRIPKWQWQLESEADAR--------QSKVYSRPRK-----------Q 726
Query: 574 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINED--------EPVKA 625
E ++ +E K+ R S +WQ A +++QE EE D E +
Sbjct: 727 EGQRRRQEQEEKRRRRE-----SELQWQEEERAHRQQQE--EEQRRDFTWQWQAEEKSER 779
Query: 626 KKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKEL 685
+++ + ++E + AE + RE+ +P E +Q + ER EKEL
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER--------EKEL 831
Query: 686 HKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRA 745
+ + + L +ER Q Q + +E++ ++++ + + ++ +EE + R
Sbjct: 832 QFLEEEEQ---LQRRERAQQL-QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 746 TFSEFAAKHAKDSRFKAIEKM--KDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELL 803
T AK A + + +++ ++ E L E R++E+E E+++ + +LL
Sbjct: 888 T---LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 804 SNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQA 863
+ + + E + +Y+ +E+ + + + + + +E E++
Sbjct: 945 REER--------EKRRRQERERQYRKDKKLQQKEE------QLLGEEPEKRRRQEREKKY 990
Query: 864 RIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRR 923
R E L++ E ++ + E+ + + ER+ K++E Q + LL + + RR
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE--------REKRR 1042
Query: 924 TLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKI 983
++ ++ L++EE E+L E E T++++E RQ E +E +++
Sbjct: 1043 LQERERQYREEEELQQEE-EQLLGEERE--TRRRQELERQYRKE------EELQQEEEQL 1093
Query: 984 IKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQH 1043
++E+P ++++++E E R++ + + + L +E R K+ QE ++
Sbjct: 1094 LREEP--------EKRRRQERERQCREEEELQQEEEQLLREE------REKRRRQELERQ 1139
Query: 1044 LKDVEKILQNDKRYLVLDCVPEERRK 1069
++ E++ Q +++ L + PE+RR+
Sbjct: 1140 YREEEEVQQEEEQLLREE--PEKRRR 1163
Score = 79.7 bits (195), Expect = 1e-14
Identities = 122/632 (19%), Positives = 277/632 (43%), Gaps = 77/632 (12%)
Query: 448 YNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK 507
Y L+ K Q+L ++E+ E + +E K +E EEE ++E + ++EE +
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 508 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 567
+ E E+ +K K + +E++ P R R + +
Sbjct: 950 KRRRQERERQYRKDKKLQQK-------------EEQLLGEEPEKR-----RRQEREKKYR 991
Query: 568 VDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSM----SAIKEEQELMEEINEDEPV 623
++ +Q+ + EE +K R Q+W+ +EE++L+ E E +
Sbjct: 992 EEEELQQEEEQLLREEREKRRR--------QEWERQYRKKDELQQEEEQLLREEREKRRL 1043
Query: 624 KAKKRKRDDNKDIDSEKEAAMEAEIKAARERAI---VPLEARMKQFKDMLLERGVSAFST 680
+ ++R+ + +++ E+E + E + R + + E ++Q ++ LL
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Query: 681 WEKEL-----HKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKM 735
E+E ++ + LL +E+++ + + R EEE ++++ ++++ + + ++
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 736 ME-EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEK 794
E E ++ + + ++ + K + ++RE + E R+K K+ + R E
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEK---RRQERERQYREEEELQRQKRKQ--RYRDED 1218
Query: 795 IKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSE 854
+SD + ++ R +KV K + +++ ++ S +R+ +Q ++ + L +
Sbjct: 1219 QRSD-LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHL---LGEQ 1274
Query: 855 KEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSS 914
+E++ E++ R ++R+R + E+ E + ++E +R+ Q K LL + R
Sbjct: 1275 QERDREQERR---RWQQRDRHFPE---EEQLEREEQKEAKRRDRKSQEEKQLLRE-EREE 1327
Query: 915 DVSWSDTRRTLRKDHRW---ESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAI 971
+T R R++ + L R+E+++ F E + +E R+ L+E +
Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE----ELRHQEQGRKFLEEEQRL 1383
Query: 972 TLTSTWKEVKKIIKEDP--RCIKFSSS-----DRKKQREFEEYIRD----KYITAKADFR 1020
+ +K +KE+ RC + DRK + E ++ R K+ + R
Sbjct: 1384 ---RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 1021 TLLKETKFITYRSKKLIQESDQHLKDVEKILQ 1052
+E KF+ ++L QE + ++ E++LQ
Sbjct: 1441 RQERERKFLE-EEQQLRQERHRKFREEEQLLQ 1471
Score = 75.9 bits (185), Expect = 2e-13
Identities = 105/609 (17%), Positives = 265/609 (43%), Gaps = 36/609 (5%)
Query: 464 KEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKP 523
+++E+ E++++ +E E+ L E EEE +++ +E +EE +E+++ E++ ++ +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 524 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 583
+ ++++ R R L + ++ Q+ ++ +
Sbjct: 390 RREQQLRREQQL---RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 584 LKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAA 643
LK+ + L ++ + +Q+L + E+ + K + ++ ++ +E
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 644 MEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERK 703
+ E + RE+ + + ++ ++ L +R S E++L + + R LL +E K
Sbjct: 507 LRREQEERREQRL-----KRQEEEERLQQRLRS-----EQQLRREQEERREQLLKREEEK 556
Query: 704 QVFDQYVKTRAEEERREKKNKIMQAKEDFK----KMMEEAKFNPRATFSEFAAKHAKDSR 759
++ + + R + E+ E+++++++ +E+ + K +E + R E ++ R
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 760 FKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKD 819
+ +++ + E + + + ++E+ + R E+ + L + + K +
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676
Query: 820 KVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSE----KEKELERQARIEASLRERERE 875
+ E + A + + K I K L+SE + K R + E R +E+E
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736
Query: 876 VQKARSE---QTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWE 932
++ R E Q +E +R Q + EE ++F +S + R ++ R
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796
Query: 933 SGSLLEREEKEKLF---NEHIEALTKKKREHFRQL--LDETSAITLTSTWKEVKKIIKED 987
ER+++E+ F E E +++RE ++L L+E + +++++ +ED
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE--EED 854
Query: 988 PRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDV 1047
D++++R E+ K+ + R + T + ++ +++ Q L++
Sbjct: 855 G-----LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 1048 EKILQNDKR 1056
E+ LQ ++R
Sbjct: 910 EEELQREER 918
Score = 72.8 bits (177), Expect = 2e-12
Identities = 104/544 (19%), Positives = 239/544 (43%), Gaps = 83/544 (15%)
Query: 458 EKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPK-EEPIKEIKEEPKEEEMTEEEK 516
++ Q+L+ +E+ ++ ++ ++ EE + +E D K E ++++ + +E + EEE+
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 517 AAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVD-KIIQEP 575
++ ER + +L + +R + + R + D K ++E
Sbjct: 1454 QLRQ---------------------ERHRKFREEEQL-LQEREEQQLHRQERDRKFLEEE 1491
Query: 576 PHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINE----DEPVKAKKRKRD 631
+ E +K R ++ + ++EEQ+L + + E + ++++R
Sbjct: 1492 QQLRRQERDRKFREQ-----ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 632 DNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFD 691
+ D +++ E +++ RE + + R ++F+ L E+ V +++ K + D
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR--LEEQKVRR----QEQERKFMED 1600
Query: 692 PRYLLLNPKERKQVFDQYVKTRAEEER-REKKNKIMQAKEDFKKMMEEAKFNPRATFSEF 750
+ L +++ ++ K R +E+ +E++ + + +E +K +EE R E
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP-QLRRQEREQ 1659
Query: 751 AAKHAKDSRFKAIEKM-----------KDREALFNEFVAAARKKEKE------DSKTRGE 793
+H +D +F+ E++ ++R+ F E R++E+E + + R +
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 794 KIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRY-KAVDSSSMREDLFKQYIEKIAKNLD 852
+++ F E + Q R ++++ RY K ++ +R + +Q + + ++
Sbjct: 1720 ELERKFRE-------EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 853 SEKEKELERQARIEASLRERE-----REVQKARSEQTKEIDR----------EREQHKRE 897
+E++L RQ R E LR +E RE ++ R E+ ++ R E EQ + E
Sbjct: 1773 FREEEQL-RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 898 EAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKE-KLFNEHIEALTKK 956
E Q + R+ + + + + W+ R+E+E KL EHI K+
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 957 KREH 960
++ H
Sbjct: 1892 EQRH 1895
Score = 70.1 bits (170), Expect = 1e-11
Identities = 116/589 (19%), Positives = 237/589 (40%), Gaps = 74/589 (12%)
Query: 442 DGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKE 501
D + + +R LE E Q ++K + +E+ +E SE+ +E + ++E +
Sbjct: 118 DQRRFEPRDRQLEE--EPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 502 IKEEPKE-EEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPD 560
++E +E EE EE+ Q K T P DE L R +
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFP----------DEEQLRRRELLELRRKGREE 225
Query: 561 DLIGRAD-VDKIIQEPPHKKGME-------ELKKLRHPTPTMLSIQKWQFSMSAIKEEQE 612
R + D++ QE K+ + E +KL+ P + + E QE
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285
Query: 613 LMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLE 672
L E E+E + + R+ + E+ + E + +ER E R +Q + E
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 673 RGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDF 732
R R L ++ ++ +Q ++ EEERRE++ + Q
Sbjct: 346 R-------------------REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 733 KKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRG 792
+++ E + R + ++ + + ++++ + L E R ++K + + R
Sbjct: 387 QQLRREQQLR-REQQLRREQQLRREQQLRREQQLRREQQLRRE-QEEERHEQKHEQERRE 444
Query: 793 EKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLD 852
+++K + + + W K +++ E + + ++ D Q E+ + L
Sbjct: 445 QRLKRE---------QEERRDWLKREEETERHEQERR--KQQLKRD---QEEERRERWLK 490
Query: 853 SEKEKELERQARIEASLREREREVQKARSEQTKEIDR-----EREQHKREEAIQNFKALL 907
E+E+ E+Q R E LR + E ++ R ++ +E +R EQ R E + + LL
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 908 SDMVRSSDVSWSDTRR--TLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLL 965
R + RR L+++ LL+REE+ + + L +++ E Q L
Sbjct: 551 K---REEEKRLEQERREQRLKREQEERRDQLLKREEERRQ-----QRLKREQEERLEQRL 602
Query: 966 DETSAITLTSTWKEVKKIIKEDP---RCIKFSSSDRKKQREFEEYIRDK 1011
L + +++ +E+P R + S+ +++R ++ R++
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651
Score = 60.8 bits (146), Expect = 7e-09
Identities = 94/483 (19%), Positives = 207/483 (42%), Gaps = 70/483 (14%)
Query: 619 EDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAF 678
E+EP + +++KR + E+E A E +ER LE R +Q +D L R
Sbjct: 130 EEEPGQRRRQKRQEQ-----ERELAEGEEQSEKQER----LEQRDRQRRDEELWR---QR 177
Query: 679 STWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAE-------------EERREKKNKI 725
W++ + + + E ++ D+ R E ++RRE+++++
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 726 MQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEK 785
Q +E E ++ R T + ++ + ++++ E + ++E+
Sbjct: 238 FQEEE-------EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 786 EDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 845
++ + + ++++ R +++ K E + R + + +E +Q E
Sbjct: 291 QEEEQQQQRLR----------------REQQLRRKQEEERREQQEERREQQERR-EQQEE 333
Query: 846 KIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQH-KREEAIQNFK 904
+ + L E+E+ E+Q R E RE+++++ + E+ +E REQ +RE+ ++ +
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 905 ALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKE-----KLFNEHIEALTKKKRE 959
L + + + LR++ + L RE++E K E E K+++E
Sbjct: 394 QLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 960 HFRQLL---DETSAITLTSTWKEVKKIIKED--PRCIKFSSSDRKKQRE--------FEE 1006
R L +ET +++K+ +E+ R +K +R++Q+E +E
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Query: 1007 YIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLK-DVEKILQNDKRYLVLDCVPE 1065
R++ + + + L + + ++ + +Q LK + EK L+ ++R L E
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 1066 ERR 1068
ERR
Sbjct: 573 ERR 575
Score = 59.3 bits (142), Expect = 2e-08
Identities = 101/581 (17%), Positives = 243/581 (41%), Gaps = 93/581 (16%)
Query: 462 ELKEKEKLEEKIKEPIKE---PSEEPLPMETEEE----DPKEEPIKEIKEEPKEEEMTEE 514
E +E+++ +E+ + ++ P EE L E ++E D K + K++ E +EE+ +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 515 EKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQE 574
E + + +E++ + +R + + R + D+ +E
Sbjct: 1333 ETDRK------------------FREEEQL----------LQEREEQPLRRQERDRKFRE 1364
Query: 575 PP------HKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELM-----EEINEDEPV 623
+K +EE ++LR + + +KEEQ+L +++ +D
Sbjct: 1365 EELRHQEQGRKFLEEEQRLR----------RQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 624 KAKKRKRDDNKDIDSEKEAAMEAEIKAA-RERAIVPLEARMKQFKDMLLERGVSAFSTWE 682
K ++ ++ ++ K E +++ RER + E +++Q + E
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 683 KE-LHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEER-REKKNKIMQAKEDFKKMMEEAK 740
++ LH+ D ++L + R+Q D+ K R +E R +E + K ++ ++ + + K
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDR--KFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 741 F-----NPRATFSEFAAKHAKDSRFKAIEKMK-DREALFNEFVAAARKKEKEDSKTRGEK 794
F R + +D +F+ E+++ +RE RK E+ K R ++
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 795 IKSDFFE---LLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSM-REDLFKQYIEKIAKN 850
+ F E L Q R + + E + + + + R++ ++++E+ +
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 851 LDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDM 910
E+E++L + RE E+ +Q+ +Q + +R+R+ + E+ ++ +
Sbjct: 1653 RRQEREQQLRHDR--DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER----- 1705
Query: 911 VRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSA 970
R+ L+++ + L + +E+ + E +++E +R++L+E
Sbjct: 1706 ----------ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQL 1755
Query: 971 ITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDK 1011
+ ++ ++ R KF ++ +Q E+ +R +
Sbjct: 1756 RP-----EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Score = 33.9 bits (76), Expect = 0.87
Identities = 40/236 (16%), Positives = 105/236 (44%), Gaps = 24/236 (10%)
Query: 821 VESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKAR 880
++ + R + S+ +D ++ ++ + D + E+E ++ R + +ERE + +
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 881 SEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLERE 940
SE+ + ++ +R++ +R+E + + W + ++ + +S E E
Sbjct: 155 SEKQERLE-QRDRQRRDEELWRQRQ-----------EWQEREERRAEEEQLQSCKGHETE 202
Query: 941 E---KEKLFNEHIEALTKK----KREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKF 993
E +E+L + L +K K++ R+ D W++ + +++++ K
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE--KL 260
Query: 994 SSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEK 1049
+ ++QRE +E ++ K + + L +E + + ++L +E K E+
Sbjct: 261 QEEEPQRQRELQE---EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 93.2 bits (230), Expect = 1e-18
Identities = 138/695 (19%), Positives = 290/695 (41%), Gaps = 97/695 (13%)
Query: 399 TGVLPGMAPPIVPMIHPQVAIAASPATLAGATA---------VSEWTEYKTADGKTYYYN 449
T ++PG + + +H A A + + E T+ + A Y N
Sbjct: 157 TSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRN 216
Query: 450 NRTLESTWEKPQELKEKEKLEEKIKEPIK-EPSEEPLPMETEEEDPKEEPIKEIKEE--P 506
T E +K EL+EK L E K I+ E +E + + ++EE
Sbjct: 217 TITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR 276
Query: 507 KEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRA 566
+EEE+ E+EK +K + +W +ER+ R + R
Sbjct: 277 QEEELREQEKKIRKQEE------------KMWRQEERL-------------REQEGKMRE 311
Query: 567 DVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAK 626
+K+ ++ K+ E+ K+LR + ++ + ++E++E M E E + +
Sbjct: 312 QEEKMWRQ--EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Query: 627 KRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELH 686
K R + + + EK+ + + +E + + R+++ ++ + E+ WE ++
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE----KMWE-QVE 424
Query: 687 KIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRAT 746
K+ +E K++ +Q KTR +EE+ +++ +I +E KKM EE
Sbjct: 425 KM-----------REEKKMQEQEKKTRDQEEKMQEEERI---REREKKMREE-------- 462
Query: 747 FSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEK----EDSKTRGEKIKSDFFEL 802
E + ++ K E M ++E + +KEK E + + EKI ++
Sbjct: 463 --EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 803 LSNHHLDSQSR--WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELE 860
+ Q + W + K + + D ++ + +E E++ K +++K +
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 861 RQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALL----SDMVRSSDV 916
++ ++ R RERE +K R E+ ++E + ++EE +Q + + M +
Sbjct: 581 QEEKMREEERMRERE-KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 917 SWSDTRRTLRKDHR-WESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTS 975
W + ++ + WE L E+KEKL+ EH + ++K + + + E + +
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRL--PEQKEKLW-EHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 976 TWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKK 1035
+E K +E R + KK RE EE +R+ + + + + +K
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMREEEEMMRE--------------QEEKMQEQEEK 742
Query: 1036 LIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKL 1070
+ ++ ++ + EK+ + +++ +PE++ KL
Sbjct: 743 MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Score = 90.5 bits (223), Expect = 8e-18
Identities = 126/591 (21%), Positives = 247/591 (41%), Gaps = 68/591 (11%)
Query: 454 ESTWEKPQELKEKEK-LEEKIKE--PIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK--- 507
E W + + L+E+EK L E+ KE KE E+ M+ +EE E+ K ++E K
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 508 -EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLS--MWDRPDDLIG 564
EE + E+EK ++ + +W DER+ R MW++
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEER-----MWEQDERLREKEERMREQEKMWEQ------ 422
Query: 565 RADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINE----- 619
V+K+ +E KK E+ KK R M ++ + ++EE+E M E E
Sbjct: 423 ---VEKMREE---KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Query: 620 DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFS 679
+E + ++ K + + +KE E E +E I E +++ ++M +
Sbjct: 477 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK----K 532
Query: 680 TWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAK--EDFKKMME 737
W +E + D + ++ +++ DQ K +EER EKK + + K + +KM E
Sbjct: 533 MWRQEKMREQEDQMW-----EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587
Query: 738 EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKS 797
E + R E + ++ + EKM+++E E ++E++ + + +
Sbjct: 588 EERMRER----EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 798 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 857
+ + Q R + K+K+ + + + +E+ + + K + EK+
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 858 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSD----MVRS 913
+ + R E S+RERE+ K R E+ ++E + ++EE +Q + + + M
Sbjct: 704 WDQEKMREEESMREREK---KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ 760
Query: 914 SDVSWSDTRRTLRKDHRWESGSL------LEREEKEKLFNEHIEALTKKKREHFRQLLDE 967
+ W R +K+ WE + E+EEK + E + +K R ++ +
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ 820
Query: 968 TSAI---------TLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIR 1009
+ W + +K+ ++ + + +K RE EE +R
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Score = 81.6 bits (200), Expect = 4e-15
Identities = 102/576 (17%), Positives = 257/576 (44%), Gaps = 84/576 (14%)
Query: 450 NRTLESTWEKPQELKEKEKL-----------EEKIKEPIKEPSEEPLPMETEEEDPKEEP 498
N E W + +EL+E+EK EE+++E + E+ M +E+ +E+
Sbjct: 268 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE 327
Query: 499 IKEIKEEPKE----EEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLS 554
KE++E+ KE +E+ E+E+ Q+ + +W +E++
Sbjct: 328 -KELREQEKELREQKELREQEEQMQEQEEK------------MWEQEEKM----REQEEK 370
Query: 555 MWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSI-QKWQFSMSAIKEEQEL 613
MW + + L + K+ E+ +K+R M ++ + ++E++++
Sbjct: 371 MWRQEERLWEQ-----------EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 614 MEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLER 673
E++ E ++ +K+ ++ K ++E E E RE+ + E M++ ++ + ++
Sbjct: 420 WEQV---EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Query: 674 GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDF- 732
+ + EKE + P++++++++Q EE+ E++ KI +E +
Sbjct: 477 EENMWEQEEKEWQQQRL--------PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 528
Query: 733 --KKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREA-LFNEFVAAARKKEKEDSK 789
KKM + K + +D ++ EKM+D+E ++++ +K ++++ K
Sbjct: 529 QEKKMWRQEKM-----------REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Query: 790 TRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAK 849
T ++ K + + R + K + E + + + +E+ ++ EK+ +
Sbjct: 578 TWDQEEKM---------REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWE 628
Query: 850 NLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSD 909
+ +E+E + + E + E+ ++ R + KE E E+ + +E +Q + + +
Sbjct: 629 QEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE 688
Query: 910 MVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETS 969
+ + ++T ++ E S+ ERE+K + E + +K +E ++ ++
Sbjct: 689 QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Query: 970 AITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFE 1005
+ W++ +K+ +++ + + +K++ +E
Sbjct: 749 EM-----WEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/472 (20%), Positives = 204/472 (43%), Gaps = 42/472 (8%)
Query: 451 RTLESTWEKPQELKEKEKLEEKIKEPIKEPSE-----EPLPMETEEEDPKEEPIKEIKEE 505
R E ++ + ++E+EK + +E ++E E E E EE++ +++ + E KE+
Sbjct: 440 RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499
Query: 506 PKEEE--MTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRL---SMWDRPD 560
E+E +EEK ++ + + +W G E+ + R MW++ +
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQE-------EMW-GQEKKMWRQEKMREQEDQMWEQEE 551
Query: 561 DLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINED 620
+ + +E KK E+ KK M ++ + ++EE+E+M E E
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 621 EPVKAKKRKRDDNK------DIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLE-R 673
+ +K + + K + ++E E E K + + + R+ + K+ L E
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 674 GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFK 733
+ +++ KI + ++ K+ +DQ K R EE RE++ K M+ +E+
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ-EKMREEESMREREKK-MREEEEMM 729
Query: 734 KMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEK--EDSKTR 791
+ EE + E + ++ ++ EKM ++E E +KEK E K +
Sbjct: 730 REQEE-----KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 792 GEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKI---A 848
++ + E + + + + K++ + E R + E ++ Q EK+
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQEEKMRGQ-EEKMRGQEEKMWGQEEKMWGQE-EKMWGQE 842
Query: 849 KNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 900
+ + ++EK E+ E +RE+E +K R ++ K ++E + +EE I
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQE---EKMRGQEEKMREQEEKMRGQEEKI 891
Score = 48.1 bits (113), Expect = 4e-05
Identities = 66/370 (17%), Positives = 160/370 (43%), Gaps = 62/370 (16%)
Query: 435 WTEYKTADGKTYYYNNRTLESTW-----EKPQELKEKEKLEEKIKEPIKEPSEEPLPMET 489
W + + + KT +T + E+ +E ++K + EE++ +E +E
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 490 EEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYN- 548
E+E+ E +E K + +EE+M E+E+ +W +E+++
Sbjct: 621 EQEEKMWE--QEEKMQEQEEKMWEQEEK-------------------MWEQEEKMWEQQR 659
Query: 549 -PTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAI 607
P + +W+ H+K M+E +K++ + +K +
Sbjct: 660 LPEQKEKLWE-------------------HEK-MQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 608 KEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFK 667
+++ E++ E+E ++ +++K + +++ E+E M+ + + +E+ E M + +
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ-----EEEMWEQE 754
Query: 668 DMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQ 727
+ + E+ WE++ + + +E++++++Q K R +EE+ + + M+
Sbjct: 755 EKMWEQ---EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 728 AKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKE- 786
+E+ + EE + E ++ + EKM +E E + +K +E
Sbjct: 812 GQEEKMRGQEEKMWG-----QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 787 DSKTRGEKIK 796
+ K RG++ K
Sbjct: 867 EEKMRGQEEK 876
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 84.0 bits (206), Expect = 7e-16
Identities = 90/410 (21%), Positives = 135/410 (32%), Gaps = 44/410 (10%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGP 91
P PPP+ P + P PP P P PP P P++ +P P PP P
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLAT----PLPLAPP--SPSAPPSLQTLPSPPATPPSQAP 369
Query: 92 PHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTP----ALPPTEEIWVENKTPDGKV 147
P + PP PP PP + P + AP +P +L T +
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 148 YYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQA 207
+ R +++ T P + +P L A + A Q +
Sbjct: 430 LTMSPRQTQASLTSPS--RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487
Query: 208 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA 267
QA + A QA + + ++ Q TP S
Sbjct: 488 PLQA---------------LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 268 PAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQD-QTPSSAVSVATPTV--SVSTPAP 324
P + S + P T++ T +T P Q P S ++ P S++TP P
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592
Query: 325 TATPVQTVPQ----PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIP---L 377
A P P P P P A P P A+P PP PL + P
Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA 652
Query: 378 PGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLA 427
P + ++ P+ + P + P P P V+ +A+P + A
Sbjct: 653 PNALAVHLLQAPFSPPPS-------PPVQAPFSPPASPPVSPSATPPSQA 695
Score = 82.0 bits (201), Expect = 3e-15
Identities = 97/411 (23%), Positives = 140/411 (34%), Gaps = 40/411 (9%)
Query: 15 NPGELRMAQQQALRFRGPAPPPN--AVMRGP---PPLMRPPPPFGMMRGPPPPPRPPFGR 69
+P + + QALR PP A GP PL P P R PPP
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL 327
Query: 70 PPFDPNMPPMPPPGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGT 127
P P PP+ P + P P PP LQ P PP PP M PP P P
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLP-SPPATPPSQAPPSMTTPPMQAP---PSL 383
Query: 128 PALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQA 187
+PP + ++ T S P + + T + + Q
Sbjct: 384 QTIPP--------------IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 188 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQV 247
+ Q QA + ++ + QA A Q + +
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 248 QAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTT---STTTTATSVAQTVSTPTTQDQ 304
QA + P +S P + T +S + PS T S TT +++ P Q
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ-- 547
Query: 305 TPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364
+++ + TP + + P P P+Q P P T PP P S+ P P PP +
Sbjct: 548 --TASAPLTTPHLE-TPPCPAPCPLQAPPSP-LTTPPPETPSSIATPP---PQAPPALAS 600
Query: 365 PFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHP 415
P PL G+P P P + + P +PP+ P+ P
Sbjct: 601 P---PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP 648
Score = 77.0 bits (188), Expect = 9e-14
Identities = 91/356 (25%), Positives = 121/356 (33%), Gaps = 40/356 (11%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGP-PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMG 90
PA PP + + P P +++ P PPP PP + PF P P P PP
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPVSPSATPPSQA 695
Query: 91 PPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
PP L PP PP PP M P PP AP A PP + V P
Sbjct: 696 PPSLAAPPLQVPPSPPASPP---MSPSATPPPQAPPPLAAPPLQ---VPPSPPA------ 743
Query: 151 NARTRESAWTKPDGVKVIQQSELTPMLAA-QAQVQAQAQAQAQAQAQAQAQAQAQAQAQA 209
+ P + P+LAA QV A A+ QA A
Sbjct: 744 ---------SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA---PPA 791
Query: 210 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPA 269
A QA A QA A QA A P + +P
Sbjct: 792 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 270 VSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPV 329
+ TP TS + ++A P ++PSS +S P ++ + + T+TP
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS--GPDLAGHSSSATSTPE 909
Query: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM-----VPP--FRVPLPGMPIPLP 378
+ + P + P P + A P PP FR PG P+P P
Sbjct: 910 ELRGY---DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR-GAPGAPLPWP 961
Score = 73.9 bits (180), Expect = 8e-13
Identities = 100/404 (24%), Positives = 131/404 (32%), Gaps = 58/404 (14%)
Query: 46 LMRPPPPFGMMRGPPPPPRPPFG--RPPFDPNMPPMPPPG--GIPPPMGPPHLQRPPFMP 101
L+ PP PP PP PP + N+P + PP P+ PHL+ PP
Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLE-NLPSLAPPPLQTASAPLTTPHLETPPCPA 565
Query: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTK 161
P PP P PP P A P PP A
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPP-------------------------ALAS 600
Query: 162 PDGVKVIQQSELTPMLAAQAQVQ---AQAQAQAQAQAQAQAQAQAQAQAQAQA-QAQAQA 217
P ++ + L+P+ Q A QA A A QA A A
Sbjct: 601 PP-LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS-S 276
QA QA A V QA A+ P P+P S S S
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719
Query: 277 STPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPH 336
+TP A + S P + +PS+ TP P P+ P
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA------------TPPPRVPPLLAAP--- 764
Query: 337 PQTLPPAVPHSVPQPTTAIPA--FPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTV 394
P +PP+ P S+P A P PP + P LP P PG A + + +
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 395 ATTKTGVLPGMAPPIV-----PMIHPQVAIAASPATLAGATAVS 433
AT P +A P++ P P + P T T+VS
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868
Score = 62.0 bits (149), Expect = 3e-09
Identities = 99/418 (23%), Positives = 145/418 (34%), Gaps = 51/418 (12%)
Query: 33 APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPF--------DPNMPPMPPPGG 84
A P + PP RPPPP GR P +P P G
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 85 IPPPMGPPHLQRPPFMPPPMSS----MPP----PPGMMFPPGMPPVTAPGTPALPPTEEI 136
P R P PP S PP PG + PG T P I
Sbjct: 79 --PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 137 WVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQ 196
E GK R+ SA + D S TP + A + A +
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRD------TSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256
A + A+ + + ++ + A + + A+ + A +Q + + A
Sbjct: 191 RPAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 257 GASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT 316
S+P S P+ A T + + PS A Q TP +D P+ ++P
Sbjct: 248 PLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSP- 303
Query: 317 VSVSTPAPTATPVQTVPQPH------PQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPL 370
++TP+P+ T + VP P P TLPP+ P + P P A P PP L
Sbjct: 304 --LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL----APPSPSAPPSLQTL 357
Query: 371 PGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPI-VPMIHPQVAIAASPATLA 427
P P P A + + P ++ + +T PPI VP ++ A P+ LA
Sbjct: 358 PSPPATPPSQAPPSMTT-PPMQAPPSLQT------IPPIQVPHSLTSPSLQAPPSPLA 408
Score = 60.8 bits (146), Expect = 7e-09
Identities = 88/363 (24%), Positives = 109/363 (30%), Gaps = 49/363 (13%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PA PP + PP P ++ PP PP P P P PP PPP
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-------PMSPSATPPPQAPPP 729
Query: 89 MGPPHLQRPPFMP--PPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGK 146
+ P LQ PP P PPMS P PP +PP+ A +PP+
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATP-----PPRVPPLLAAPPLQVPPSPP----------- 773
Query: 147 VYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQ 206
A S KP + TP L A A QA A A
Sbjct: 774 -----ASLPMSPLAKPP--PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
Query: 207 AQAQA-QAQAQAQAQAQAQAQAQAQAQAQAQAQAQA-QVQAQVQAQVQAQAVGASTPTTS 264
QA A Q A QA + A A G P +
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886
Query: 265 SPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAP 324
SP+ +S + SS TST P + ++ P PAP
Sbjct: 887 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946
Query: 325 ----TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGM--PIPLP 378
P +P P P + P + P P PG P P P
Sbjct: 947 PLAFRGAPGAPLPWP---------PATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997
Query: 379 GVA 381
G +
Sbjct: 998 GTS 1000
Score = 52.8 bits (125), Expect = 2e-06
Identities = 108/493 (21%), Positives = 161/493 (32%), Gaps = 124/493 (25%)
Query: 44 PPLMRPPPPFGMMRGPPPPPRPP----------FGRPPF--------DPNMPPMPPPGGI 85
P L+ P PP G R PPPP P GR P +P P G
Sbjct: 22 PGLLTPRPP-GSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG- 78
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPP--PPGMMFPPGMPPVTAPGT--------PALPPTEE 135
P R P PP S PP PG PV++PG P
Sbjct: 79 -PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG--PVSSPGRASGTTRPGPLGQKGLR 135
Query: 136 IWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195
I E GK R+ SA + D S TP + A + A +
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRD------TSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQA 255
A + A+ + + ++ + A + + A+ + A +Q + + A
Sbjct: 190 PRPAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 256 VGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP 315
S+P S P+ A T + + PS A Q TP +D P+ ++P
Sbjct: 247 TPLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSP 303
Query: 316 TVSVSTPAPTATPVQTVPQPH------PQTLPPAVPHSVPQPTT--------------AI 355
++TP+P+ T + VP P P TLPP+ P + P P +
Sbjct: 304 ---LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Query: 356 PAFPPVM------------------VPPFRVP---------LPGMPIPLPGVAMMQIVSC 388
PA PP +PP +VP P P+ L + +
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
Query: 389 PYVK------------TVATTKTGVLPGMAPPIVP----------------MIHPQVAIA 420
P ++ T A+ + P PP P + P V+
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
Query: 421 ASPATLAGATAVS 433
+SP T+ A+S
Sbjct: 481 SSPLTIHPLQALS 493
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 84.0 bits (206), Expect = 7e-16
Identities = 58/125 (46%), Positives = 66/125 (52%), Gaps = 16/125 (12%)
Query: 16 PGELRMAQQQALRFRGPAPP---PNAVMRGPPPLMRPPPPFGMMRGPPP---PPRPPFGR 69
PG + A R P PP P G PP +RPP G+ RGP P PP PP GR
Sbjct: 408 PGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGL-RGPLPRLLPPGPPPGR 466
Query: 70 PPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPM-SSMPPP-PGMMFPPGMPPVTAPGT 127
PP PP PPP G+PP GPP PP +PPP +PPP PGMM PP +PP+ P
Sbjct: 467 PP---GPPPGPPP-GLPP--GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPL-GPAP 519
Query: 128 PALPP 132
P L P
Sbjct: 520 PGLFP 524
Score = 68.6 bits (166), Expect = 3e-11
Identities = 39/90 (43%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
Query: 44 PPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIP-PPMGPPHLQRPPFMPP 102
PP PP ++ PP P PP G PP P PP PP G P PP G P RPP MP
Sbjct: 393 PPQSVPP---SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPG 449
Query: 103 PMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
+P + PPG PP PG P PP
Sbjct: 450 LRGPLP----RLLPPGPPPGRPPGPPPGPP 475
Score = 67.8 bits (164), Expect = 5e-11
Identities = 45/105 (42%), Positives = 52/105 (49%), Gaps = 22/105 (20%)
Query: 28 RFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPP 87
R P PPP G PP P PP G+ GPPP P P +PP P P GIPP
Sbjct: 456 RLLPPGPPP-----GRPPGPPPGPPPGLPPGPPPRGPP--------PRLPP-PAPPGIPP 501
Query: 88 PMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
P P + RPP +PP P PPG +FPP P+ PG + PP
Sbjct: 502 PR--PGMMRPPLVPP---LGPAPPG-LFPPA--PLPNPGVLSAPP 538
Score = 52.0 bits (123), Expect = 3e-06
Identities = 73/350 (20%), Positives = 121/350 (34%), Gaps = 59/350 (16%)
Query: 172 ELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 231
ELTP+ A ++ Q + + + ++ + + ++A+ Q+Q Q + ++ +
Sbjct: 326 ELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSD---DSEAEKQSQKQHKEESHSDG 382
Query: 232 QAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATS 291
+ A +Q QA Q+ +Q+QA + P PAP +
Sbjct: 383 TSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP------------------ 424
Query: 292 VAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVP------QPHPQTLPPAVP 345
PT P P A P P P P+ LPP P
Sbjct: 425 ---------------------GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPP 463
Query: 346 HS-----VPQPTTAIPAFPPVMVPPFRVPLPGMP-IPLPGVAMMQIVSCPYVKTVATTKT 399
P P +P PP PP R+P P P IP P MM+ P V +
Sbjct: 464 PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMR---PPLVPPLGPAPP 520
Query: 400 GVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEK 459
G+ P P ++ + P + A E T K N + E T
Sbjct: 521 GLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKA-EITRFV 579
Query: 460 PQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEE 509
P L+ + + + P + SE+ + + PK P + + K++
Sbjct: 580 PTALRVRRENKGATAAP-QRKSEDDSAVPLAKAAPKSGPSVPVSVQTKDD 628
Score = 51.2 bits (121), Expect = 5e-06
Identities = 36/94 (38%), Positives = 38/94 (40%), Gaps = 24/94 (25%)
Query: 60 PPPPRPP--FGRPPFDPNMPPMPPPGGIP-------------PPMGPPHLQRPPFMPPPM 104
PP PP PP P PP+ PP P PP G P RPP MP
Sbjct: 393 PPQSVPPSQIQAPPM-PGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLR 451
Query: 105 SSMP------PPPGMMFPPGMPPVTAPGTPALPP 132
+P PPPG PPG PP PG P PP
Sbjct: 452 GPLPRLLPPGPPPGR--PPGPPPGPPPGLPPGPP 483
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 83.6 bits (205), Expect = 1e-15
Identities = 53/115 (46%), Positives = 61/115 (53%), Gaps = 14/115 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP + PPPPP P G PP P +PP PP P
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPG-MPPVTAPGTPALPP 132
G GIPPP P + PP P P + +PPP PGM PP PP+ PGT PP
Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235
Score = 79.7 bits (195), Expect = 1e-14
Identities = 52/125 (41%), Positives = 62/125 (49%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP + PPPPP P G PP P +PP PP P
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP---GMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P + PP P P + +PPPP G PP PP+ G P PP + +
Sbjct: 1137 GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGVGIPPPPPLPGVGI 1195
Query: 139 ENKTP 143
P
Sbjct: 1196 PPPPP 1200
Score = 79.3 bits (194), Expect = 2e-14
Identities = 52/125 (41%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P + PP P P + +PPP PG PP PP+ G P PP + +
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPRVGI 1151
Query: 139 ENKTP 143
P
Sbjct: 1152 PPPPP 1156
Score = 77.8 bits (190), Expect = 5e-14
Identities = 52/125 (41%), Positives = 60/125 (48%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 989 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1048
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P PP P P + +PPP PG PP PP+ G P PP + +
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGVGI 1107
Query: 139 ENKTP 143
P
Sbjct: 1108 PPPPP 1112
Score = 77.8 bits (190), Expect = 5e-14
Identities = 51/114 (44%), Positives = 58/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1070
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG+ PP PP+ G P PP
Sbjct: 1071 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP-PPPLPGAGIPPPPP 1123
Score = 77.8 bits (190), Expect = 5e-14
Identities = 52/125 (41%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1125
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP---GMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P PP P P +PPPP G PP PP+ G P PP + +
Sbjct: 1126 GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGI 1184
Query: 139 ENKTP 143
P
Sbjct: 1185 PPPPP 1189
Score = 77.0 bits (188), Expect = 9e-14
Identities = 51/114 (44%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 967 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1026
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1079
Score = 77.0 bits (188), Expect = 9e-14
Identities = 51/114 (44%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1090
Score = 76.6 bits (187), Expect = 1e-13
Identities = 50/115 (43%), Positives = 57/115 (49%), Gaps = 15/115 (13%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP-----GMMFPPGMPPVTAPGTPALP 131
G GIPPP P PP P P + +PPPP G+ PP +P P P LP
Sbjct: 1115 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169
Score = 76.3 bits (186), Expect = 2e-13
Identities = 51/114 (44%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 956 PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 1016 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1068
Score = 75.1 bits (183), Expect = 3e-13
Identities = 50/114 (43%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P +PPP PG+ PP PP+ G P PP
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP-PPPLPGAGIPPPPP 1211
Score = 74.3 bits (181), Expect = 6e-13
Identities = 46/114 (40%), Positives = 57/114 (50%), Gaps = 17/114 (14%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPP 87
P P P A + PPPL + PPPP + PPPPP P G PP PP P GIPP
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP-----PPPLPGAGIPP 1208
Query: 88 P-----MGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEI 136
P MG P PP +PPP + +PPPP + P PP+ + PT ++
Sbjct: 1209 PPPLPGMGIPPAPAPP-LPPPGTGIPPPP--LLPVSGPPLLPQVGSSTLPTPQV 1259
Score = 72.4 bits (176), Expect = 2e-12
Identities = 51/115 (44%), Positives = 57/115 (49%), Gaps = 15/115 (13%)
Query: 32 PAPP-PNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP- 81
P PP P A + PPPL + PPPP P PPP P G PP P +PP PP
Sbjct: 933 PLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
Query: 82 PG-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
PG GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1046
Score = 70.5 bits (171), Expect = 8e-12
Identities = 48/115 (41%), Positives = 55/115 (47%), Gaps = 16/115 (13%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDPNMP----PMPPP- 82
P P P A + PPPL + P PP PPPPP P PP P +P P+PPP
Sbjct: 912 PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP-PPPLPGAGIPLPPPL 970
Query: 83 --GGIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1024
Score = 67.0 bits (162), Expect = 9e-11
Identities = 42/96 (43%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPG-GIP 86
P P P + PPPL + PPPP PPPPP P G PP PP+PPPG GIP
Sbjct: 1176 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA--PPLPPPGTGIP 1233
Query: 87 PPMGPPHLQRPPFMPPPMSSMPPPPGM--MFPPGMP 120
PP P + PP +P SS P P + PP +P
Sbjct: 1234 PPPLLP-VSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 66.2 bits (160), Expect = 2e-10
Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 16/106 (15%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGP 91
P PPP ++G L PPPP PPPPP P G P +PP+ P GIPPP
Sbjct: 897 PQPPP---LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILP----LPPL-PGAGIPPPPPL 948
Query: 92 PHLQRPPFMPPPMSS----MPPP-PGMMFPPGMPPVTAPGTPALPP 132
P PP PPP+ +PPP PG PP PP+ G P PP
Sbjct: 949 PGAAIPP--PPPLPGAGIPLPPPLPGAGIPP-PPPLPGAGIPPPPP 991
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/115 (41%), Positives = 56/115 (48%), Gaps = 15/115 (13%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPF--GMMRGPPPPPRPPFGRPPFDP--NMPPMPP-P 82
P P P A + PPPL + PPPP + PPP P PP P +PP PP P
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1103
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP-----GMMFPPGMPPVTAPGTPALP 131
G GIPPP P PP P P + +PPPP G+ PP +P V P P LP
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Score = 58.2 bits (139), Expect = 4e-08
Identities = 42/115 (36%), Positives = 50/115 (43%), Gaps = 15/115 (13%)
Query: 32 PAPPP------NAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN--MPPMPPP- 82
P+PPP ++ M G + PPPP M P P PP +PP PPP
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 83 --GGIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
GIPPP P P P P + +PPP PG PP PP+ G P PP
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP-PPPLPGAGIPLPPP 969
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/88 (39%), Positives = 41/88 (46%), Gaps = 18/88 (20%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPP--PRPP--FGRPPFDPNMPPMPPPG 83
P P P + PPPL + PPPP M PP P P PP G PP PP+ P
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP-----PPLLPVS 1241
Query: 84 GIP--PPMGPPHLQRPP---FMPPPMSS 106
G P P +G L P F+PPP+ S
Sbjct: 1242 GPPLLPQVGSSTLPTPQVCGFLPPPLPS 1269
Score = 43.5 bits (101), Expect = 0.001
Identities = 47/174 (27%), Positives = 62/174 (35%), Gaps = 30/174 (17%)
Query: 230 QAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTA 289
Q Q +Q + Q + + ++ SP P T +SSS P
Sbjct: 822 QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPP 881
Query: 290 TSVAQTVSTPTTQDQTPSSAVSVATPT--VSVSTPAPTATPVQTVPQPHPQT------LP 341
TV T PS+A+ P + P P P +P P P LP
Sbjct: 882 PLPGMTVPT------LPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP 935
Query: 342 P----AVPHSVPQPTTAIPAFPP-----VMVPPFRVPLPGM----PIPLPGVAM 382
P +P P P AIP PP + +PP PLPG P PLPG +
Sbjct: 936 PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP---PLPGAGIPPPPPLPGAGI 986
Score = 43.1 bits (100), Expect = 0.001
Identities = 42/136 (30%), Positives = 53/136 (38%), Gaps = 22/136 (16%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHP---QTLPP-------AVPHSVPQPTTAI 355
P + + P V P P P +P P P +PP +P P P I
Sbjct: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGI 1151
Query: 356 PAFPPVM---VPPFRVPLPGM----PIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPP 408
P PP+ +PP PLPG P PLPGV I P + V LPG P
Sbjct: 1152 PPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGVG---IPPPPPLPGVGIPPPPPLPGAGIP 1207
Query: 409 IVPMIHPQVAIAASPA 424
P + P + I +PA
Sbjct: 1208 PPPPL-PGMGIPPAPA 1222
Score = 41.2 bits (95), Expect = 0.005
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 24/163 (14%)
Query: 264 SSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPA 323
S P ++ST +S S +S + ++ P T+ S + P + + P
Sbjct: 827 SQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES-------SSSMPGLGMVPPP 879
Query: 324 PTATPVQTVPQPHPQTLPP-AVPHSVPQPTTAIPAFPPVMVPPFRVPLPGM--PIPLPGV 380
P P TVP TLP A+P P P PP PP +P G+ P PLPG
Sbjct: 880 PPPLPGMTVP-----TLPSTAIPQ--PPPLQGTEMLPP---PPPPLPGAGIPPPPPLPGA 929
Query: 381 AMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASP 423
++ + P + LPG A P P + P I P
Sbjct: 930 GILPL---PPLPGAGIPPPPPLPGAAIPPPPPL-PGAGIPLPP 968
Score = 40.4 bits (93), Expect = 0.009
Identities = 27/65 (41%), Positives = 31/65 (47%), Gaps = 8/65 (12%)
Query: 31 GPAPPPNAVMRGPPPLMRPP-PPFGMMRGPPPPPRPPFGRPPFDPNM--PPMPPP---GG 84
G PPP G PP PP PP G G PPPP P PP P + +P P G
Sbjct: 1205 GIPPPPPLPGMGIPPAPAPPLPPPG--TGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
Query: 85 IPPPM 89
+PPP+
Sbjct: 1263 LPPPL 1267
Score = 39.3 bits (90), Expect = 0.021
Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPVM-- 362
P + + + P P P P +P P P LP A +P P P IP PP+
Sbjct: 960 PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Query: 363 -VPPFRVPLPGM----PIPLPGVAM 382
+PP PLPG P PLPG +
Sbjct: 1018 GIPP-PPPLPGAGIPPPPPLPGAGI 1041
Score = 39.3 bits (90), Expect = 0.021
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 12/109 (11%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPVMVP 364
P + + P V P P P +P P P LP A +P P P IP P +P
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP--LPGAGIPPPPPLPGMGIPPAPAPPLP 1226
Query: 365 PFRVPLPGMPIPLPGVAMMQIVSCPYVKTV--ATTKTGVLPGMAPPIVP 411
P PG IP P ++ + P + V +T T + G PP +P
Sbjct: 1227 P-----PGTGIPPP--PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 38.9 bits (89), Expect = 0.027
Identities = 43/173 (24%), Positives = 60/173 (34%), Gaps = 13/173 (7%)
Query: 190 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQV-QAQVQ 248
+ A AQ + + + + A Q + Q + Q Q Q Q Q Q+ Q Q Q
Sbjct: 164 ETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQ 223
Query: 249 AQVQAQAVGASTPTTSSPAPAVSTSTSSST--PSSTTSTTTTATSVAQTVSTPTTQDQTP 306
Q+Q A+ PT SP P PS + Q +S P
Sbjct: 224 QQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALS---ALSDLP 280
Query: 307 SSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFP 359
S A P P+P PV P +LP A P + P++ FP
Sbjct: 281 ESL--AAEPREPQQPPSPGGLPVSEAP-----SLPAAQPAAKDSPSSTAFPFP 326
Score = 38.5 bits (88), Expect = 0.035
Identities = 66/298 (22%), Positives = 108/298 (36%), Gaps = 45/298 (15%)
Query: 115 FPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174
FP +P + G P+ PP EE +E+ + + + E+ + D V Q E+
Sbjct: 618 FPRRVPSM---GPPSKPPDEEHRLEDAETESQ-----SAVSETPQKRSDAV----QKEVV 665
Query: 175 PMLA-AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 233
M + QA V Q + + A+ + Q A A + A +A
Sbjct: 666 DMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEA 725
Query: 234 QAQAQAQAQVQAQVQAQ-VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
+ + + ++A+ +Q T P + + + T + +
Sbjct: 726 LRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEI 785
Query: 293 AQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPP---------A 343
+ VS Q S PT S+S P P + + + Q P + PP +
Sbjct: 786 SLIVSPRRISVQLDSHQ-----PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTS 840
Query: 344 VPHSVPQP---TTAIPAFPPV-------------MVPPFRVPLPGMPIP-LPGVAMMQ 384
HSV + IP+ PP+ MVPP PLPGM +P LP A+ Q
Sbjct: 841 HEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQ 898
Score = 31.2 bits (69), Expect = 5.6
Identities = 25/88 (28%), Positives = 29/88 (32%), Gaps = 16/88 (18%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPH-------------LQRPPFMPPPMS 105
PPPPP + P PP I H + PP +P S
Sbjct: 810 PPPPPSLLWSA---GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES 866
Query: 106 SMPPPPGMMFPPGMPPVTAPGTPALPPT 133
S P M PP PP+ P LP T
Sbjct: 867 SSSMPGLGMVPPPPPPLPGMTVPTLPST 894
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 83.2 bits (204), Expect = 1e-15
Identities = 120/641 (18%), Positives = 272/641 (42%), Gaps = 99/641 (15%)
Query: 462 ELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE----------------- 504
EL+E+ +++++ K+ ++E + L + + + + +K+
Sbjct: 191 ELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQ 250
Query: 505 -EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRL---SMWDRPD 560
EP+ E T+EE +PV GT + T +RV + ++ +
Sbjct: 251 LEPQAEVFTKEENPESDGEPVVE---DGTSVKTLETLQQRVKRQENLLKRCKETIQSHKE 307
Query: 561 DLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINED 620
+ +QE ++ ++EL+K++ L + + ++ +++ + L+E++ +D
Sbjct: 308 QCTLLTSEKEALQEQLDER-LQELEKIKD-----LHMAEKTKLITQLRDAKNLIEQLEQD 361
Query: 621 EPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFST 680
+ + + KR ++ ++ ++E EI R R I + + ++ ++ + +AF
Sbjct: 362 KGMVIAETKRQMHETLEMKEE-----EIAQLRSR-IKQMTTQGEELREQKEKSERAAF-- 413
Query: 681 WEKELHKIVFDPRYLLLNPKERKQVFDQYVKT---RAEEERREKKNKIMQAKEDFKKMME 737
+EL K + + ++ K D+ +KT +EEER + ++ + K++ +M+
Sbjct: 414 --EELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK 471
Query: 738 EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKS 797
++ A + K + +K++ RE F E + A +K
Sbjct: 472 KSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK-------------- 517
Query: 798 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 857
SQS + K+ + E A++ +++ E ++L E E
Sbjct: 518 ------------SQSEYLKISQEKEQQESL-ALEELELQKKAILTESENKLRDLQQEAET 564
Query: 858 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI--QNFKALLSDMVRSSD 915
R +E+SL + +E + + ++ E+ +H +E + + K L + D
Sbjct: 565 YRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQD 624
Query: 916 VSWSDTRRTLRKDHRWESGSLLEREEKEK---------LFNEHIEALTKKKREHFRQLLD 966
W++ + L++ ++ E L E+ E+EK +F HIE + +K E +
Sbjct: 625 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLD--VK 682
Query: 967 ETSAITLTSTWKEVKKI---IKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLL 1023
+T +L+S EV K ++E+ +K +D+ KQ E E + ++ + +++
Sbjct: 683 QTELESLSSELSEVLKARHKLEEELSVLK-DQTDKMKQ-ELEAKMDEQKNHHQQQVDSII 740
Query: 1024 KETKFITYRSKK-----------LIQESDQHLKDVEKILQN 1053
KE + R++K L++E D+HLK+ + ++N
Sbjct: 741 KEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 781
Score = 59.7 bits (143), Expect = 1e-08
Identities = 123/648 (18%), Positives = 270/648 (41%), Gaps = 93/648 (14%)
Query: 454 ESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTE 513
E+ + + L+ KE+ +++ IK+ + + + ++E + +E+++ + TE
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTE 427
Query: 514 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 573
E + KA+ DE++ T+ +L + V + +
Sbjct: 428 EARRKLKAEM-----------------DEQIKTIEKTSEEERISLQQEL---SRVKQEVV 467
Query: 574 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEI------NEDEPVKAKK 627
+ K E++ KL+ L+ ++ + + E+E E++ ++ E +K +
Sbjct: 468 DVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQ 527
Query: 628 RKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHK 687
K + + + E+ + I E + L+ + ++ +LE S+ EK L +
Sbjct: 528 EK-EQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE----LESSLEKSLQE 582
Query: 688 IVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATF 747
+ L ++ + K ++ + E+ + E ++ Q + + ++ K +
Sbjct: 583 NKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 642
Query: 748 SEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKK--EKEDSK-TRGEKIKSDFFELL- 803
+ K ++ +KD+E +F + +K EK D K T E + S+ E+L
Sbjct: 643 EKLREKCEQEKE----TLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLK 698
Query: 804 SNHHLDSQ-----SRWSKVKDKVES------DPRYKAVDSSSMREDLFKQYIEKIAKN-- 850
+ H L+ + + K+K ++E+ + + VDS ++ Q EK K+
Sbjct: 699 ARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQI 758
Query: 851 -----LDSEKEKEL-ERQARI---EASLREREREVQKARS-------------EQTKEID 888
L E++K L E QA + EA ++ E E+Q+A + EQTK +
Sbjct: 759 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 818
Query: 889 REREQHKREEA-IQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFN 947
+ Q +++ ++ + LL+ V + D L H+ + L+++ EK+ N
Sbjct: 819 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTEL-DAHKIQVQDLMQQLEKQ---N 874
Query: 948 EHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEY 1007
+E K + + L++ + ++ K+I+ E I +KK+ E
Sbjct: 875 SEMEQKVKSLTQVYESKLEDGN-----KEQEQTKQILVEKENMILQMREGQKKEIE---- 925
Query: 1008 IRDKYITAKADFRTLLK---ETKFITYRSKKLIQESDQHLKDVEKILQ 1052
I + ++AK D +L ETKF +K +++ Q K++++ L+
Sbjct: 926 ILTQKLSAKEDSIHILNEEYETKF--KNQEKKMEKVKQKAKEMQETLK 971
Score = 49.3 bits (116), Expect = 2e-05
Identities = 107/597 (17%), Positives = 231/597 (38%), Gaps = 83/597 (13%)
Query: 448 YNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE--- 504
YN + E Q+L+ ++L E+ +KE E+ L +E + K E + KE
Sbjct: 1551 YNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEH 1610
Query: 505 -----EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRP 559
+ KEEE+ E + A + ++++ M ++
Sbjct: 1611 VNLSVKSKEEELKALEDRLESESAAKLAELKR-------KAEQKIAAIKKQLLSQMEEK- 1662
Query: 560 DDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINE 619
E +KKG E H + +Q+ + + ++E+ + +E
Sbjct: 1663 --------------EEQYKKGTES-----HLSELNTKLQEREREVHILEEKLKSVESSQS 1703
Query: 620 DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFS 679
+ + + K + ++EA + ++ E I L+ + + + +L G
Sbjct: 1704 ETLIVPRSAK--NVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEE 1761
Query: 680 TWEKELH-KIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNK-----IMQAKEDFK 733
T + + R + L E KQ DQ + +EE EK K +++
Sbjct: 1762 TVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG 1821
Query: 734 KMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGE 793
K +AK N F + + I + K +E + + ++KE + E
Sbjct: 1822 KNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE------LDSCLVRQKEVHRVEME 1875
Query: 794 KIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDS 853
++ S + +L + +D +++ +++ ++ + + + ++ Q+ + K +
Sbjct: 1876 ELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1935
Query: 854 EKEKEL--ERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMV 911
E+EK+ + R++ LR +E Q+ KE D+ERE+ ++E
Sbjct: 1936 EREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQ------------ 1983
Query: 912 RSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAI 971
++ + T + L ++ + + +E E E I + + E +ET+ +
Sbjct: 1984 EDLELKHNSTLKQLMREFNTQLAQ--KEQELEMTIKETINKAQEVEAELLESHQEETNQL 2041
Query: 972 TLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYI--RDKYITAKA-DFRTLLKE 1025
+KKI ++D ++ + +EE + R++ +TAK D +T L+E
Sbjct: 2042 --------LKKIAEKD-------DDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEE 2083
Score = 44.7 bits (104), Expect = 5e-04
Identities = 87/478 (18%), Positives = 195/478 (40%), Gaps = 56/478 (11%)
Query: 595 LSIQKWQFSMSAIKEEQE---LMEEINE-DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKA 650
L IQ S A +++++ L EE+++ ++ K + +D+K +KE+ +E E+K+
Sbjct: 1463 LQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKS 1522
Query: 651 ARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV 710
R I+ LE + Q K + +E + ++ + KE Q +
Sbjct: 1523 QTAR-IMELEDHITQ-KTIEIESLNEVLKNYNQQKD----------IEHKELVQKLQHFQ 1570
Query: 711 KTRAEEERR--EKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKD 768
+ E++ R E + KI+ + M E + + + +K+ KA+E +
Sbjct: 1571 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1630
Query: 769 REALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVES----- 823
E+ +A ++K ++ +++ S E + ++S S++ K++
Sbjct: 1631 SESAAK--LAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREV 1688
Query: 824 ---DPRYKAVDSSSMREDLFKQYIEKIAKNLDS-EKEKELERQARIEASLREREREVQKA 879
+ + K+V+SS + + + AKN+ + +++E + Q ++ + E+ +Q+
Sbjct: 1689 HILEEKLKSVESSQSETLI----VPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRN 1744
Query: 880 RSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLER 939
+E+ K + R Q K E +F+ R + ++ ++ +D E
Sbjct: 1745 LTEKEKLLQRV-GQEKEETVSSHFEMRCQYQERLIKLEHAEAKQ--HEDQSMIGHLQEEL 1801
Query: 940 EEKEKLFN----EHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSS 995
EEK K ++ +H+E K +Q L + + +V+K ++E +
Sbjct: 1802 EEKNKKYSLIVAQHVEKEGGKNNIQAKQ--------NLENVFDDVQKTLQEKELTCQILE 1853
Query: 996 SDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQN 1053
K+ D + + + + E Y + +Q+ D K E + +N
Sbjct: 1854 QKIKE--------LDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEEN 1903
Score = 42.7 bits (99), Expect = 0.002
Identities = 84/440 (19%), Positives = 182/440 (41%), Gaps = 50/440 (11%)
Query: 603 SMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEAR 662
S+ + EE E + N+++ ++ K+K + ++ +K EA++K E + L +
Sbjct: 937 SIHILNEEYETKFK-NQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQK 995
Query: 663 MKQFKDMLLER----------GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKT 712
KQF +LE VS T +KE + + + LN + ++++ +
Sbjct: 996 EKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQ 1053
Query: 713 RAEE-------ERREKKNKIMQAKEDFKKM-MEEAKFNPRATFSEFAAKHAKDSRFKAIE 764
+AEE + +EK+ ++ + K+ E+ + N T+ + + + E
Sbjct: 1054 QAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQE 1113
Query: 765 KMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESD 824
++K + A N +++ K EK++ D + L + Q + ++K E D
Sbjct: 1114 QLKQKSAHVNSLA-----QDETKLKAHLEKLEVDLNKSLKENTF-LQEQLVELKMLAEED 1167
Query: 825 PRYKAVDSSSMR--EDLFKQYIEKIAKNLDSEKEKELERQ--------------ARIEAS 868
R + +S ++ ++ F+ K+ S ++K LE + + EA
Sbjct: 1168 KRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEAL 1227
Query: 869 LREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDV-----SWSDTRR 923
L + E+ S +T I R H + + +ALL S++ ++ +
Sbjct: 1228 LEAKTNELINISSSKTNAI-LSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQN 1286
Query: 924 TLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAIT-LTSTWKEVKK 982
TL + + L E+E + K IE+L +K ++ ++ A + S ++KK
Sbjct: 1287 TLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKK 1346
Query: 983 IIKEDPRCIKFSSSDRKKQR 1002
+ E+ + + K+++
Sbjct: 1347 ELSENINAVTLMKEELKEKK 1366
Score = 36.2 bits (82), Expect = 0.17
Identities = 47/278 (16%), Positives = 121/278 (43%), Gaps = 16/278 (5%)
Query: 717 ERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 776
+R +KK + + ++ K + A+ + A KH ++ ++E+ ++
Sbjct: 168 QREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQ 227
Query: 777 VAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMR 836
V+ +++ R + D + L L+ Q+ ++ ESD D +S++
Sbjct: 228 VSLLKQR------LRNGPMNVDVLKPLPQ--LEPQAEVFTKEENPESDGEPVVEDGTSVK 279
Query: 837 EDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERERE-VQKARSEQTKEIDREREQHK 895
Q K +NL ++ KE + + + +L E+E +Q+ E+ +E+++ ++ H
Sbjct: 280 TLETLQQRVKRQENL-LKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 338
Query: 896 REEA-----IQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHI 950
E+ +++ K L+ + + + ++T+R + + + + + + K
Sbjct: 339 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 398
Query: 951 EALTKKKREHFRQLLDE-TSAITLTSTWKEVKKIIKED 987
E L ++K + R +E A++ +E ++ +K +
Sbjct: 399 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAE 436
Score = 35.0 bits (79), Expect = 0.39
Identities = 78/381 (20%), Positives = 163/381 (42%), Gaps = 60/381 (15%)
Query: 638 SEKEAAMEAEIKAARERAIVPLE-ARMKQFK-DMLLERGVSA----------FSTWEKEL 685
SEKEAA+ + K E L+ + FK D L + +SA FS W+K+
Sbjct: 1390 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKA 1449
Query: 686 HKIVFDPR--------YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAK-EDFKKMM 736
+ L L KE + +Q + E +++ K+ ++ + ED K M
Sbjct: 1450 QSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKM 1509
Query: 737 EEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIK 796
E+ + N A+ + +K + E+L NE + +++ + K +K++
Sbjct: 1510 EKKESNLETELKSQTAR-IMELEDHITQKTIEIESL-NEVLKNYNQQKDIEHKELVQKLQ 1567
Query: 797 --SDFFELLSNHHLDSQSRWSKVKDKV-----ESDPRYKAVDSSSMREDLFKQYIEKIAK 849
+ E N +++ + ++++V E + + K ++ ++ ++ ++ +
Sbjct: 1568 HFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALED 1627
Query: 850 NLDSE---KEKELERQA---------RIEASLREREREVQKARSEQTKEI-----DRERE 892
L+SE K EL+R+A ++ + + E+E + +K E+ +RERE
Sbjct: 1628 RLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERERE 1687
Query: 893 QHKREEAIQNFKALLSD----------MVRSSDVSWSDTRRTLRKDHRWESGSLLERE-- 940
H EE +++ ++ S+ + ++ +D++ ++K + E S+L+R
Sbjct: 1688 VHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYE-EKISVLQRNLT 1746
Query: 941 EKEKLFNEHIEALTKKKREHF 961
EKEKL + + HF
Sbjct: 1747 EKEKLLQRVGQEKEETVSSHF 1767
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 80.5 bits (197), Expect = 8e-15
Identities = 51/119 (42%), Positives = 58/119 (48%), Gaps = 17/119 (14%)
Query: 33 APPPNAVMRGPPPLMRPPPPFGMMR-GP----PPPPRPPFGRPPFDP--NMPPMPPPGGI 85
A PPN R PPP++ P PFG GP PPPP P +G PP P P PPPG
Sbjct: 264 AGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPF 323
Query: 86 PP----PMGPP-HLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPAL-----PPTE 134
PP P+GPP L PP +P P PPP + P PP T G P PPT+
Sbjct: 324 PPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTD 382
Score = 73.2 bits (178), Expect = 1e-12
Identities = 61/145 (42%), Positives = 67/145 (46%), Gaps = 39/145 (26%)
Query: 28 RFRGPA-----PPPNAVMRGPP--PLMRP-------PPPFGMM----------RG--PPP 61
RF GPA PPP + PP PL P PPP G + RG PPP
Sbjct: 216 RFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPP 275
Query: 62 P---PRPPFGRPPFDPNMPPMPP---PGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMF 115
P P PFG+PP P +PP PP PG PPP PP Q PP PPP P PPG +
Sbjct: 276 PVLFPGQPFGQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPP--PPPGPFPPRPPGPLG 332
Query: 116 PP--GMPPVTAPGTP--ALPPTEEI 136
PP PP PG P A PP +
Sbjct: 333 PPLTLAPPPHLPGPPPGAPPPAPHV 357
Score = 69.3 bits (168), Expect = 2e-11
Identities = 53/125 (42%), Positives = 58/125 (46%), Gaps = 31/125 (24%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRG--PPPP---PRPPFGRPPFDPNMPPMPPPG-- 83
GP PPP V+ PPPL PP RG PPPP P PFG+PP P +PP PPP
Sbjct: 251 GP-PPPGQVL--PPPLAGPPN-----RGDRPPPPVLFPGQPFGQPPLGP-LPPGPPPPVP 301
Query: 84 ------GIPPPMGPPHLQRPPFMP-------PPMSSMPPPPGMMFPPGMPPVTAPGTPAL 130
G PPP P PF P PP++ PPP PPG PP PA
Sbjct: 302 GYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAF 361
Query: 131 --PPT 133
PPT
Sbjct: 362 FPPPT 366
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/125 (36%), Positives = 53/125 (42%), Gaps = 20/125 (16%)
Query: 31 GPAPPPNAVMRGPPPLM-----RPPPPFG---MMRGPPPPPRPPFGRPPFDPNMPP--MP 80
GP P P +GPPP RPP P G + PP P PP G PP P++ P P
Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363
Query: 81 PP--GGIP--PPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEI 136
PP G+P GPP P+ PP P G PPG TA + EEI
Sbjct: 364 PPTNSGMPTSDSRGPP--PTDPYGRPP----PYDRGDYGPPGREMDTARTPLSEAEFEEI 417
Query: 137 WVENK 141
N+
Sbjct: 418 MNRNR 422
Score = 34.7 bits (78), Expect = 0.51
Identities = 23/66 (34%), Positives = 24/66 (36%), Gaps = 6/66 (9%)
Query: 315 PTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMP 374
P V P P P Q P P P PP P + P T P P P PG P
Sbjct: 298 PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP------PHLPGPPPGAP 351
Query: 375 IPLPGV 380
P P V
Sbjct: 352 PPAPHV 357
Score = 33.9 bits (76), Expect = 0.87
Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 2/58 (3%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPG 379
P P A P +P P L P P P P +P PP VP + P PG P P G
Sbjct: 260 PPPLAGPPNRGDRPPPPVLFPGQPFGQP-PLGPLPPGPPPPVPGYGPP-PGPPPPQQG 315
Score = 30.4 bits (67), Expect = 9.6
Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 9/90 (10%)
Query: 324 PTATPVQTVPQPHPQTLPPAV--PHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVA 381
P P P P P PP P P P +P PP+ PP R P P+ PG
Sbjct: 227 PPPFPAGQTP-PRPPLGPPGPPGPPGPPPPGQVLP--PPLAGPPNRGDRPPPPVLFPGQP 283
Query: 382 MMQIVSCPYVKTVATTKTGVLPGMAPPIVP 411
Q P + + +PG PP P
Sbjct: 284 FGQ----PPLGPLPPGPPPPVPGYGPPPGP 309
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 80.5 bits (197), Expect = 8e-15
Identities = 48/107 (44%), Positives = 53/107 (49%), Gaps = 14/107 (13%)
Query: 32 PAPPPNAVMRGPPPLM---RPPPPFGM-MRGPPPPPRPPF--GRPPFDPNMPPMPPPGGI 85
PAPPP PPP++ PPPP G G PPPP PP P F PP PPP
Sbjct: 320 PAPPPP-----PPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAAD 374
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
P + PP L +P PP PPPPG PP P A G PA+PP
Sbjct: 375 YPTLPPPPLSQPTGGAPPPPPPPPPPG---PPPPPFTGADGQPAIPP 418
Score = 71.6 bits (174), Expect = 4e-12
Identities = 46/112 (41%), Positives = 49/112 (43%), Gaps = 14/112 (12%)
Query: 32 PAPPPNAVMRGP-----PPLMRPPPPFGMMRGPPPPPRPPFGRP-----PFDPNMPPMPP 81
P PP GP PP PPPP M+ PPPPP FG P P P+ PP P
Sbjct: 301 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD 360
Query: 82 PGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPT 133
PPP PP P PPP+S P G PP PP PG P P T
Sbjct: 361 FAAPPPPPPPPAADYPTLPPPPLSQ--PTGGA--PPPPPPPPPPGPPPPPFT 408
Score = 68.2 bits (165), Expect = 4e-11
Identities = 39/84 (46%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 50 PPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPM-SSMP 108
PPP + G PP P+P F PP P PP PP GIPPP P P PPP S P
Sbjct: 300 PPPAPPL-GSPPGPKPGFAPPPAPP--PPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFP 356
Query: 109 PPPGMMFPPGMPPVTAPGTPALPP 132
P P PP PP A P LPP
Sbjct: 357 PHPDFAAPPPPPPPPAADYPTLPP 380
Score = 58.2 bits (139), Expect = 4e-08
Identities = 46/110 (41%), Positives = 50/110 (45%), Gaps = 19/110 (17%)
Query: 28 RFRGPAPPPNAVMRGP--PPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGI 85
R G A P + + P PP P PP G PP P+P F PP P PP PP GI
Sbjct: 282 RGSGLAGPKRSSVVSPSHPP---PAPPLGS----PPGPKPGFAPPPAPP--PPPPPMIGI 332
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEE 135
PPP PP P PPP P PP FPP P AP P PP +
Sbjct: 333 PPPP-PPVGFGSPGTPPP----PSPPS--FPPH-PDFAAPPPPPPPPAAD 374
Score = 56.6 bits (135), Expect = 1e-07
Identities = 43/127 (33%), Positives = 47/127 (37%), Gaps = 42/127 (33%)
Query: 32 PAPPPNAVMRGPPPLMR----PPPPFGM-----------MRGPP---------PPPRPPF 67
P PP + P P PPPP + GP PPP PP
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 68 GRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM--MFPPGMPPVTAP 125
G PP P PG PPP PP PPPM +PPPP PG PP P
Sbjct: 307 GSPPG-------PKPGFAPPPAPPPP-------PPPMIGIPPPPPPVGFGSPGTPP--PP 350
Query: 126 GTPALPP 132
P+ PP
Sbjct: 351 SPPSFPP 357
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 9/81 (11%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP--RPPFGRPPFDPNMPPMPPPGGIPPPM 89
P+ PP+ PPP PPPP PPPP +P G PP PP PPP PPP
Sbjct: 353 PSFPPHPDFAAPPP--PPPPPAADYPTLPPPPLSQPTGGAPP-----PPPPPPPPGPPPP 405
Query: 90 GPPHLQRPPFMPPPMSSMPPP 110
P +PPP+S P
Sbjct: 406 PFTGADGQPAIPPPLSDTTKP 426
Score = 44.7 bits (104), Expect = 5e-04
Identities = 38/125 (30%), Positives = 49/125 (39%), Gaps = 6/125 (4%)
Query: 252 QAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVS 311
Q ++G +S P S S+S+PS + S A+ S P + A
Sbjct: 231 QNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAE-FSYPVDNQRGSGLAGP 289
Query: 312 VATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP 371
+ VS S P P A P+ + P P P PP P P P IP P PP P
Sbjct: 290 KRSSVVSPSHPPP-APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPP----PPVGFGSP 344
Query: 372 GMPIP 376
G P P
Sbjct: 345 GTPPP 349
Score = 35.8 bits (81), Expect = 0.23
Identities = 24/82 (29%), Positives = 28/82 (34%), Gaps = 7/82 (8%)
Query: 299 PTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQ--PHPQTLPPAVPHSVPQPTTAIP 356
P P + + P V +P P + P PHP P P P P P
Sbjct: 319 PPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAP--PPPPPPPAADYP 376
Query: 357 AFPPVMVPPFRVPLPGMPIPLP 378
PP PP P G P P P
Sbjct: 377 TLPP---PPLSQPTGGAPPPPP 395
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 77.8 bits (190), Expect = 5e-14
Identities = 49/123 (39%), Positives = 58/123 (47%), Gaps = 19/123 (15%)
Query: 23 QQQALRFRGPAPPPNAVMRGPPPL------MRPPPPF-----GMMRGPPPPPRPPFGRPP 71
QQ+AL PPP A + PPPL + P PP G PPPPP PP PP
Sbjct: 641 QQKAL------PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL-PPP 693
Query: 72 FDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMS-SMPPPPGMMFPPGMPPVTAPGTPAL 130
PP PPP +P PP+ PP PPP + PPPPG+ F G P PA+
Sbjct: 694 SSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAI 753
Query: 131 PPT 133
P+
Sbjct: 754 EPS 756
Score = 38.9 bits (89), Expect = 0.027
Identities = 47/186 (25%), Positives = 71/186 (38%), Gaps = 35/186 (18%)
Query: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380
+PAP PV P P PP P +P P++A P PP PP PLP P P P
Sbjct: 666 SPAPPMPPVSAGPPLPP---PPPPPPPLPPPSSAGP--PPPPPPP---PLPNSPAP-PNP 716
Query: 381 AMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKT 440
P PG+APP P + + +S + A+ K
Sbjct: 717 GGPPPAPPP-------------PGLAPPPPPGLF--FGLGSSSSQCPRKPAIEPSCPMKP 761
Query: 441 ADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEP-IKEPSEEPLPMETEEEDPKEEPI 499
++R+ +T L + ++EP I++PSE + K++P+
Sbjct: 762 LYWTRIQISDRSQNAT----------PTLWDSLEEPDIRDPSEFEYLFSKDTTQQKKKPL 811
Query: 500 KEIKEE 505
E E+
Sbjct: 812 SETYEK 817
Score = 35.4 bits (80), Expect = 0.30
Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 7/54 (12%)
Query: 85 IPPPMGPPHLQRPPFMPPPMSSMPPPP-----GMMFP-PGMPPVTAPGTPALPP 132
+ P G Q+ PPP S PPPP G + P P MPPV+A G P PP
Sbjct: 631 LQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSA-GPPLPPP 683
Score = 33.9 bits (76), Expect = 0.87
Identities = 44/168 (26%), Positives = 64/168 (38%), Gaps = 17/168 (10%)
Query: 315 PTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGM- 373
P VS P P P P PP P P P + PA P PP P PG+
Sbjct: 672 PPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNS--PAPPNPGGPPPAPPPPGLA 729
Query: 374 PIPLPGVAM---MQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGAT 430
P P PG+ CP K + P P+ P+ ++ I + + A T
Sbjct: 730 PPPPPGLFFGLGSSSSQCP-------RKPAIEPSC--PMKPLYWTRIQI-SDRSQNATPT 779
Query: 431 AVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIK 478
E D + Y + ++T +K + L E + + K+K+ IK
Sbjct: 780 LWDSLEEPDIRDPSEFEY-LFSKDTTQQKKKPLSETYEKKNKVKKIIK 826
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 77.8 bits (190), Expect = 5e-14
Identities = 94/398 (23%), Positives = 145/398 (36%), Gaps = 29/398 (7%)
Query: 26 ALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGI 85
A P P A +R P P P + P P P P + P P +
Sbjct: 978 ATTVHAPEEPDTAAVRVSTP-EEPASPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAV 1033
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFP-PGMP--PVTAPGTPALPPTEEIWVENKT 142
PPP P P P P P P P P P A TP P + V T
Sbjct: 1034 PPPEEPTS----PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--T 1087
Query: 143 PDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQ 202
P+ A T P + +P A + + A A + A
Sbjct: 1088 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA 1147
Query: 203 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPT 262
++ + A A + A A A++ + A V A ++ + + AS PT
Sbjct: 1148 PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE---EPTSPAASVPT 1204
Query: 263 TSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVS---V 319
PA V+T ++P+++ T+ S+A VS P ++ ++ PT S V
Sbjct: 1205 ---PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAV 1261
Query: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTT---AIPAFPPVMVPPFRVPLPGMP-I 375
TP ++P +VP P P A ++ +P + A+P +P VP P +P I
Sbjct: 1262 LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAI 1321
Query: 376 PLPGVAMMQIVS---CPYVKTVATTKTGVLPGMAPPIV 410
P V M+ VS P++ A T + + P++
Sbjct: 1322 PAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVL 1359
Score = 55.1 bits (131), Expect = 4e-07
Identities = 74/312 (23%), Positives = 101/312 (32%), Gaps = 45/312 (14%)
Query: 233 AQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
A A +A V A + + A A+ + APAV+ + + S+ + ++
Sbjct: 899 AAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAAL 958
Query: 293 AQTVSTPTTQDQTPSSAVSVATPT----------VSVSTPAPTATPVQTVPQPHPQTLPP 342
A TV T +D TP V+ AT V VSTP A+P VP P T P
Sbjct: 959 AITVPI-TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPA 1017
Query: 343 AVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVL 402
A + +PT+ A P PP P +P P + P T+ +
Sbjct: 1018 AAVPTPEEPTSPAAAVP----PPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAV 1072
Query: 403 PGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQE 462
P P P V P + A A E A T P+E
Sbjct: 1073 PTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--------------PEE 1116
Query: 463 LKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAA---- 518
+EP + P P EEP P EE A
Sbjct: 1117 PASPAAAVPTPEEPASPAAAVPTP---------EEPAFPAPAVPTPEESASAAVAVPTPE 1167
Query: 519 QKAKPVATAPIP 530
+ A P A P P
Sbjct: 1168 ESASPAAAVPTP 1179
Score = 54.7 bits (130), Expect = 5e-07
Identities = 93/431 (21%), Positives = 134/431 (31%), Gaps = 46/431 (10%)
Query: 119 MPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLA 178
+P + P A PT + ++ P + T +A P+G V+ + L P
Sbjct: 828 IPVLQRPSRTAAVPTVKDALDAALPSPE-----EGTSIAAVPAPEGTAVV--AALVPFPH 880
Query: 179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 238
V + + + A A +A A + + A A + + A A A A
Sbjct: 881 EDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAI 940
Query: 239 AQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST 298
Q + A + A+ + P T T TP++T + A VST
Sbjct: 941 TQEGMSAVAGFSPEWAALAITVPITEEDG----TPEGPVTPATTVHAPEEPDTAAVRVST 996
Query: 299 PTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAV---PHSVPQPTTAI 355
P A+P +V TP +P VP P T P A P P A+
Sbjct: 997 PEEP----------ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAV 1046
Query: 356 PAFPPVMVPPFRVPLPGMP------IPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPI 409
P P VP P P +P P + P T+ +P P
Sbjct: 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPTPEEPT 1105
Query: 410 VPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKL 469
P V PA+ A A E A T E + P +E
Sbjct: 1106 SPA--AAVPTPEEPASPAAAVPTPEEPASPAAAVPT------PEEPAFPAPAVPTPEESA 1157
Query: 470 EEKIKEPIKEPSEEP-LPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKA------K 522
+ P E S P + T E + EEP + AA A
Sbjct: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217
Query: 523 PVATAPIPGTP 533
P A+ P P
Sbjct: 1218 PAASVPTSEEP 1228
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 77.8 bits (190), Expect = 5e-14
Identities = 110/457 (24%), Positives = 149/457 (32%), Gaps = 68/457 (14%)
Query: 31 GPA-PPPNAVMRGPPPLMRPPPPFGMMRGPPPP--PRPPFGRPPFDPNMPPMPPPGGIP- 86
GPA PPP PP PP G + PP P P PP P PP G P
Sbjct: 1254 GPATPPPKGAPT--PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 87 PPMGPPHLQRPPFMPPPMSS--MPPPPGMMFPPGMPPVTAPGTPALP---------PTEE 135
PP P P P S PPP G PP + P + GTP LP PT
Sbjct: 1312 PPAATP--------PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 136 IWVENKTP--------DGKVYYYNARTRESAWTKPDGVKVI--------QQSELTPMLAA 179
E TP G + R A P G +++ TP+
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
Query: 180 QAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 239
A ++ A + A A ++ A + +
Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
Query: 240 QAQVQAQVQAQVQAQAVGAST---PTTSSPAPAVSTSTSSSTPSSTTST----TTTATSV 292
A + +A +GA T SSP +T +S P + T+T T AT
Sbjct: 1484 VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543
Query: 293 --------AQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAV 344
A TV +P P+ + ATP+ ++ P TP P P+ L +
Sbjct: 1544 PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL--LI 1601
Query: 345 PHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIP-----LPGVAMMQIVSCPYVKTVATTKT 399
P +V P+ PP + PP P P P P V + P T K
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661
Query: 400 GVL-----PGMAPPIVPMIHPQVAIAASPATLAGATA 431
G G+ P +V +A +P + TA
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITA 1698
Score = 70.9 bits (172), Expect = 6e-12
Identities = 127/542 (23%), Positives = 170/542 (31%), Gaps = 62/542 (11%)
Query: 30 RGPAPPPNAVMRGPPPLMRPPPPFGMMRGP---PPPPR-----PPFGRPPFDPNMPPMPP 81
+G PP A P P P G P PP P+ PP P P P P
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Query: 82 PGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTP-ALPPTEEIWV 138
GG+ PPP G P P ++ P P G + P PP AP TP A PP+ + +
Sbjct: 1137 KGGLATPPPKGAP--------TTPAATPPSPKGGLATP--PPKGAPTTPAATPPSPKGGL 1186
Query: 139 ENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQ 198
+P G T + P G + P A + + A
Sbjct: 1187 ATPSPKGA-----PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 199 AQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVG 257
A + A + A A + A + V +
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 258 ASTPTTSSPAPAVST----STSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVA 313
A++P +P P +T S TP + T A + TPT TPSS
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 314 T------PTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTT-AIPAFPPVMVPPF 366
T PT +TP+ P T P P PA+P PT+ A+ P P
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSP---KRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Query: 367 RVPLPGMPIPL------PGVAMMQIVSCPYVK-------TVATTKTGVLPGMAPPI--VP 411
V G P P V + + P T ++ LP + PP P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478
Query: 412 MIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEE 471
QVA ++SP A AT A + S+ P + L
Sbjct: 1479 PAPKQVATSSSPKK-APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP--IAPTATLLS 1535
Query: 472 KIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPG 531
K P E +P PK+ P PKE T K A V + G
Sbjct: 1536 KKTPATLAPKEALIPPAMTVPSPKKTP---AIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592
Query: 532 TP 533
P
Sbjct: 1593 AP 1594
Score = 69.7 bits (169), Expect = 1e-11
Identities = 112/472 (23%), Positives = 159/472 (33%), Gaps = 77/472 (16%)
Query: 31 GPA--PPPNAVMRGPPPLMRPPPPFGMMRGPPPP--PRPPFGRPPFDPNMPPMPPP---- 82
GPA PP A PP PP P G PPP P PP PP P +P
Sbjct: 1300 GPATSPPKGAPT---PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356
Query: 83 -----------GGIPPPMGPPHLQRPPFMPPPMS---SMPPPPGMMFPPGMPPVTAPGTP 128
G PP P H P PP ++P P G P + P++ P
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP 1416
Query: 129 ALPPTEEIWVENKTPDGKVYYYNARTRES-----AWTKPDGVKVIQQSELTPMLAAQAQV 183
A P T E TP A T S A + P G S+ P L A
Sbjct: 1417 ATPVTRE---GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
Query: 184 QAQAQAQAQAQAQAQAQAQAQAQAQAQA---------QAQAQAQAQAQAQAQAQAQAQAQ 234
+ + A + + +A A + + A ++ A
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533
Query: 235 AQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST-----SSSTPSSTTSTTTTA 289
+ A + + A V + T + P P + +T +SS P+ T ST A
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Query: 290 TS-----VAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAV 344
S + V++P+ ++ AV+ +P +TPAP TP T PP
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP----------TSPPVT 1643
Query: 345 PHSV---PQPTTAIPAFPPVMVPPFRVPLPGMPIP--------LPGVAMMQIVSCPYVKT 393
P S+ P ++ VP LP P P I++ P K
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703
Query: 394 VATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVS-EWTEYKTADGK 444
T K+ +PPI P + +T+A A + + KTA GK
Sbjct: 1704 PQTKKSS---ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGK 1752
Score = 68.9 bits (167), Expect = 2e-11
Identities = 82/364 (22%), Positives = 113/364 (31%), Gaps = 38/364 (10%)
Query: 34 PPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPH 93
P P + P P P PP PP P G P P PP P P G P
Sbjct: 925 PAPKGIPASPSPKGAPTPPAAT------PPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978
Query: 94 LQRPPFMPPPMSSMPP----------PPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTP 143
P P P ++ PP P G PP + P + G+PA P + TP
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK---GASTP 1035
Query: 144 DGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQA 203
A T S P + + + TP + A + A
Sbjct: 1036 P-------AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 204 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQ---AQAVGAST 260
+ + A A + A + A + A
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 261 PTTSSPAPAVSTSTSSSTPSSTTSTTTTAT--SVAQTVSTPTTQDQTPSSAVSVATPTVS 318
PTT + P ++ P TT AT S ++TP+ + + A + +P
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 319 VSTPAP---TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFP---PVMVPPFRVPLPG 372
++TP+P TP T P P P+ P P A P P P PP P P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPS-PKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 373 MPIP 376
P
Sbjct: 1268 AATP 1271
Score = 62.0 bits (149), Expect = 3e-09
Identities = 96/421 (22%), Positives = 123/421 (29%), Gaps = 63/421 (14%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP--PPRPPFGRPPFDPNMPPMPPPGGIPPP 88
GPA P + PP PP P G P P P PP PP P P P G P P
Sbjct: 953 GPATP-SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVY 148
PP ++ P P G PP P + G+PA P P G
Sbjct: 1012 PA----VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP---------LPKGA-- 1056
Query: 149 YYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQ 208
T + P G + P A + + A A +
Sbjct: 1057 ---PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113
Query: 209 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTP------- 261
A + A + A + G +TP
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT 1173
Query: 262 --TTSSPAPAVSTSTSS-----STPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAV-SVA 313
+ P+P +T S +TP++T + + PTT TP S +A
Sbjct: 1174 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 314 TPTVSVSTPAPTATPVQ-----TVPQPHPQTLPPAV------------PH-SVPQPTTAI 355
TP+ + P ATP P P PPA PH P P
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293
Query: 356 PAFP---PVMVPPFRVPLPGMPIP-----LPGVAMMQIVSCPYVKTVATTK-TGVLPGMA 406
P P P PP P P P PG + P T + K T LP
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 407 P 407
P
Sbjct: 1354 P 1354
Score = 56.6 bits (135), Expect = 1e-07
Identities = 98/439 (22%), Positives = 130/439 (29%), Gaps = 37/439 (8%)
Query: 8 GGESERFNPGELRMAQQQALRFRG----PAP-----PPNAVMRGPPPLMRPPPPFGMMRG 58
G S +P E + +L F+G PA PP+ P + P P G+
Sbjct: 822 GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLP 881
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPP---PMGPPHLQRPPFMPPPMSSMPPPPGMMF 115
P P P PF P P P P P R P + + P P G
Sbjct: 882 PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT 941
Query: 116 PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTP 175
PP P + G PA P + W P + A P G TP
Sbjct: 942 PPAATPPSPKGGPATPSPK--W----APTPPAATPPSPKGGPATPSPKGAP-------TP 988
Query: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235
A + + A + + A A A + + A
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 236 QAQAQAQVQAQVQAQVQAQAVGASTPT-TSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQ 294
A + + G +TP+ +P P +T S +T S A
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 295 TVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTA 354
T +P TP PT +TP + T P T P A P P P
Sbjct: 1109 TPPSPKGGLATPPHK---GAPTTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGG 1162
Query: 355 IPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIH 414
+ PP P P P P G+A P T A T G+A P P
Sbjct: 1163 LATPPPKGAP--TTPAATPPSPKGGLATPSPKGAP--TTPAATPPSPKGGLATP-SPKGA 1217
Query: 415 PQVAIAASPATLAGATAVS 433
P A P+ G S
Sbjct: 1218 PTTPAATPPSPKGGLATPS 1236
Score = 51.6 bits (122), Expect = 4e-06
Identities = 77/364 (21%), Positives = 128/364 (35%), Gaps = 49/364 (13%)
Query: 88 PMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
P+ P + P P P ++ P ++ P +P +P+LPP TP G
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP--SPSLPPAG-------TPPGT- 748
Query: 148 YYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQ-AQAQAQAQAQAQAQAQAQAQ 206
K DG+ S L P+ ++ + + + A A A ++ A +
Sbjct: 749 ------------KKVDGIS--HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 207 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVG-----ASTP 261
+ Q + + A + + V+A + G A+T
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 262 TTSSPAPAVSTSTSSSTPSSTTSTTTTA--TSVAQTVSTPTTQD--------QTPSSAVS 311
+ + P+P + + S+ TP S T T V+ P ++ Q P+ +++
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
Query: 312 VATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQ--PTTAIPAF---PPVMVPPF 366
++P + +TPAP P P P PPA P+ P T P + PP PP
Sbjct: 915 SSSPKKARATPAPKGIPAS--PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP- 971
Query: 367 RVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATL 426
P G P P A + P PP V P+ + AA+P
Sbjct: 972 -SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030
Query: 427 AGAT 430
+T
Sbjct: 1031 GAST 1034
Score = 47.4 bits (111), Expect = 8e-05
Identities = 113/541 (20%), Positives = 177/541 (32%), Gaps = 112/541 (20%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIP--PPM 89
PA P+ P P PP P P PP PP P P P G P PP+
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV 1642
Query: 90 GPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYY 149
P L+ P P ++ G+P P
Sbjct: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP------------------------ 1678
Query: 150 YNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQA 209
T V V E TP++ A + Q + + A+ ++
Sbjct: 1679 ----------TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Query: 210 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPA 269
A A Q + A+ + + + A +++ ASTP T++
Sbjct: 1729 PLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLAPPESK-------ASTPLTAAAFEK 1780
Query: 270 VSTSTSSSTPSSTTSTTTTATSVAQTVST-PTTQDQTPSSAVSVATPTVSVSTPAPTATP 328
V S++ S+ S + V T P Q PSS P + + +P+ P
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSS------PGLVLESPSKPLAP 1834
Query: 329 VQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP---GMPIPLP------- 378
L P +P P+P + F V+V +P P G+P+P P
Sbjct: 1835 AD------EDELLPLIP---PEPISGGVPFQSVLV---NMPTPKSAGIPVPTPSAKQPVT 1882
Query: 379 ------GVAMMQIVSCPYVK----TVATTKTGVLPGMA----PPI----VPMIHPQVAIA 420
G S P ++ T ATT+ L A P+ + A
Sbjct: 1883 KNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKA 1942
Query: 421 ASPATLAGATAVSEWT---------------EYKTADGKTY-YYNNRTLESTWEKPQ-EL 463
S L T V+ T YK+ TY + +E ++ Q
Sbjct: 1943 MSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAA 2002
Query: 464 KEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKP 523
EK K++ + I+E ++ P T +E+ +EE + E E K+ E+ + +AK
Sbjct: 2003 AEKFKVQGEAVSNIQENTQTP----TVQEESEEEEVDETGVEVKDIELVMSQANVSRAKA 2058
Query: 524 V 524
V
Sbjct: 2059 V 2059
Score = 41.2 bits (95), Expect = 0.005
Identities = 72/323 (22%), Positives = 104/323 (32%), Gaps = 48/323 (14%)
Query: 257 GASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT 316
GA TP +P T T +T S+ TT +S T A++ +P
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390
Query: 317 VSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPA----FPPVMVPPFRVPLPG 372
+ P+P P P PA P V + A P+ PP + P P
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATP--VTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
Query: 373 MPIP--------------LPGVAMMQIVSCPYVKTVATT----KTGVLPG-MAPPIVPMI 413
P LP V P K VAT+ K P M P +P +
Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508
Query: 414 HPQ--VAIAASPAT-----LAGATAVSEWTEYKTADGKTYYYNNRTLESTWE-----KPQ 461
P + A+P++ AT +S+ T A + T+ S + P+
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Query: 462 ELKEKEKLEEKIKEPIKEPS---------EEPLPMETEEEDPKEEPIKEIKEEPKEEE-- 510
E +E P PS E +P PKE P P E+
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Query: 511 MTEEEKAAQKAKPVATAPIPGTP 533
T K + PV + + +P
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSP 1651
Score = 39.3 bits (90), Expect = 0.021
Identities = 71/309 (22%), Positives = 108/309 (34%), Gaps = 45/309 (14%)
Query: 251 VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVS--TPTTQDQTPSS 308
V A + ++ P +P A TST ++T S T + V T TT P++
Sbjct: 645 VAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704
Query: 309 AVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRV 368
+ + +T AP AT V L P +P SVP P+ PP PP
Sbjct: 705 SENCPVAPSPQNTCAPLATLV----------LAPEIPKSVPSPS-----LPPAGTPPGTK 749
Query: 369 PLPGMPIPLPGVAMMQIVS----CPYVKTVAT---TKTGVLPGMAPPIVPM---IHPQVA 418
+ G+ A+ + S CP + A+ + G L +A P+ + PQ
Sbjct: 750 KVDGISHTS---ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK 806
Query: 419 I------AASPATLAG--ATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLE 470
+A P T G ++ VS + + ++ +T P K
Sbjct: 807 RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 471 EKIKEPIKE------PSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPV 524
P+ P E P P PKE P ++ MT +A P
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP- 925
Query: 525 ATAPIPGTP 533
A IP +P
Sbjct: 926 APKGIPASP 934
Score = 35.4 bits (80), Expect = 0.30
Identities = 67/301 (22%), Positives = 104/301 (34%), Gaps = 44/301 (14%)
Query: 222 QAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPT---TSSPAPAVSTSTSSST 278
+A A Q Q QA+ V A A+G PT SPAP ++++
Sbjct: 4 EATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQ 63
Query: 279 PSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQ 338
S S +T A STP + P S+ A P + + APT P P P
Sbjct: 64 ASPFPSPSTIA-------STP-LEVPFPQSSSGTALP-LGTAPEAPTFLPNLIGPPISPA 114
Query: 339 TLPPAVPHSVP----QPTTAIP----AFPPVMVPPFRVPLPGMPIPLPGVAMMQ-----I 385
L A P P P+++ P A P V P + P VA+ +
Sbjct: 115 ALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVIT 174
Query: 386 VSCPYVKTVATTKTGVLPG---------MAPPIVPMIHPQVAIAASPATLAGATAVSEWT 436
+S P + T +P +PP + P + + +G ++ + T
Sbjct: 175 LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT 234
Query: 437 EYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP-----SEEPLPMETEE 491
T + + T+ S PQ +K P+ P S + LP+ T
Sbjct: 235 PTTTLAIASPQVKDTTISSVLISPQNPGSL-----SLKGPVSPPAALSLSTQSLPVVTSS 289
Query: 492 E 492
+
Sbjct: 290 Q 290
Score = 34.7 bits (78), Expect = 0.51
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 25/203 (12%)
Query: 251 VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAV 310
V + GAS P+ S P + S + P++ + A SV + ST ++ +PS ++
Sbjct: 341 VDHSSTGASYPSQRSVIPPLP-SRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSL 399
Query: 311 SVAT-----PTVS-VSTPAPTAT----PVQTVPQPHPQTLPPAVPHS---VPQPTTAIPA 357
+VAT PT S + +P AT V +P T P V + PTT
Sbjct: 400 NVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEV 459
Query: 358 FPPVMVPPFRVPLPGMPIPLPGVAMMQIVSC--PYVKTVATTKTGVLPGMAPP------- 408
V P P+ + P +M V+ P + T + V P + P
Sbjct: 460 ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLP 519
Query: 409 --IVPMIHPQVAIAASPATLAGA 429
++ Q + PA+L GA
Sbjct: 520 SSVLVKFPTQKDLQTVPASLEGA 542
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 77.4 bits (189), Expect = 7e-14
Identities = 48/107 (44%), Positives = 53/107 (49%), Gaps = 15/107 (14%)
Query: 16 PGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN 75
PG +A L P PPP G PPL PPPP PPPPP+P F PP P
Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPP----GFPPL--PPPP------PPPPPQPGFPMPPPLPP 711
Query: 76 MPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPV 122
PP PPP + PP L PP +PPP P PP FPPG+ PV
Sbjct: 712 PPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP---FPPGLFPV 755
Score = 63.2 bits (152), Expect = 1e-09
Identities = 42/101 (41%), Positives = 50/101 (49%), Gaps = 21/101 (20%)
Query: 36 PNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGG--IPPPMGPPH 93
P A P ++ P P PPPP G PP P PP PP G +PPP+ PP
Sbjct: 664 PGAAAVAAPSVLAPTLPL------PPPP----GFPPLPPPPPPPPPQPGFPMPPPLPPP- 712
Query: 94 LQRPPFMPP--PMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
PP PP P ++PPPP + PPG+PP P P LPP
Sbjct: 713 ---PPPPPPAHPAVTVPPPP-LPAPPGVPP--PPILPPLPP 747
Score = 61.2 bits (147), Expect = 5e-09
Identities = 101/429 (23%), Positives = 141/429 (32%), Gaps = 65/429 (15%)
Query: 5 GGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGP------PPLMRPPPPFGMMRG 58
GG GG S G AQ Q PPP P P P F
Sbjct: 358 GGTGGSS-----GPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHF----- 407
Query: 59 PPPPPRPP------------FGRPPFDPNMPPMPPPGGIPP--PMGPPHLQRPPFMPPPM 104
PPPP P F R P P +PP P P P GPP PP
Sbjct: 408 PPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPP--------PPDT 459
Query: 105 SSMPPPPGMMFPPGMPPVTAPGTPAL---PPTEEIWVENKTPDGKVYYYNARTRESAWTK 161
+SM F P +PGTP L P E ++ ++ RT+ +
Sbjct: 460 NSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLRE 519
Query: 162 PDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 221
PD +Q E +P+ ++ +Q+ A +Q + ++ +
Sbjct: 520 PDSDTELQM-EGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLP 578
Query: 222 QAQAQAQAQAQAQAQAQAQ------AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
+ + + + A + +Q A+V VG TPT+ +S
Sbjct: 579 DSDEDEELDLGLGPRPPPEPGPPDPAGLLSQT-AEVALDLVGDRTPTSEKMDEGQQSSGE 637
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPA--PTATPVQTVP 333
S + TS T +A SV PT+ + P P P P
Sbjct: 638 DMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP 697
Query: 334 QPHPQ-TLPPAVPHSVPQPTTA----------IPAFPPVMVPPFRVPLPGMPIPLPGVAM 382
P P +PP +P P P A +PA P V PP PLP P PG+
Sbjct: 698 PPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFP---PGLFP 754
Query: 383 MQIVSCPYV 391
+ V +V
Sbjct: 755 VMQVDMSHV 763
Score = 47.8 bits (112), Expect = 6e-05
Identities = 86/404 (21%), Positives = 125/404 (30%), Gaps = 49/404 (12%)
Query: 52 PFGMMRGPPPPPRPPFGRPPFD-PNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPP 110
PFG + G PPF P D PPP P G P P++ PPP
Sbjct: 353 PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSP--YQTPVAHFPPP 410
Query: 111 P------------------GMMFPPGMPPV-----TAPGTPALPP---TEEIWVENKTPD 144
P PP +PP PGTP PP T + + +
Sbjct: 411 PEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTF 470
Query: 145 G----KVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQV-----QAQAQAQAQAQA 195
G T ES+ P+ S + +L Q + + + Q +
Sbjct: 471 GWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEG 530
Query: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQA 255
+ + +Q A +Q + ++ + + ++
Sbjct: 531 SPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGL 590
Query: 256 VGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP 315
P P PA S ++ T + + +D S + P
Sbjct: 591 GPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650
Query: 316 TVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPV-MVPPFRVPLPG-- 372
S P P P L P +P +P P P FPP+ PP P PG
Sbjct: 651 ITSADCPKPMVVTPGAAAVAAPSVLAPTLP--LPPP----PGFPPLPPPPPPPPPQPGFP 704
Query: 373 MPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGM-APPIVPMIHP 415
MP PLP + P V TV PG+ PPI+P + P
Sbjct: 705 MPPPLPPPPPPPPPAHPAV-TVPPPPLPAPPGVPPPPILPPLPP 747
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/152 (28%), Positives = 53/152 (34%), Gaps = 40/152 (26%)
Query: 9 GESERFNPG-----ELRMAQQQALRFRGPAPPPNAVMRGPPPL----------MRPPPPF 53
GE PG L M ++ + AP M PPL PP
Sbjct: 1170 GEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEP 1229
Query: 54 G------MMRGPPPPPRPPFGRPPFDPNMPPM-------PPPGGIPPPMGPPHLQRPPFM 100
G M+ P PP + RPP P P PP +P P+ PP +
Sbjct: 1230 GLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPP-------L 1282
Query: 101 PPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
PPP P PP PP P T P++PP
Sbjct: 1283 PPPR--PPRPPS---PPPEPETTDASHPSVPP 1309
Score = 45.1 bits (105), Expect = 4e-04
Identities = 37/126 (29%), Positives = 46/126 (36%), Gaps = 16/126 (12%)
Query: 16 PGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN 75
P E ++Q+ A+ P PP V PP P + P PP P P
Sbjct: 1226 PEEPGLSQEGAMLL-SPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPL------PL 1278
Query: 76 MPPMPPPGGIPPPMGPPH-----LQRPPFMPPPMSSMPPP--PGM--MFPPGMPPVTAPG 126
PP+PPP PP PP P P P++ PP PG+ T P
Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPA 1338
Query: 127 TPALPP 132
TP P
Sbjct: 1339 TPGGEP 1344
Score = 39.3 bits (90), Expect = 0.021
Identities = 39/130 (30%), Positives = 49/130 (37%), Gaps = 33/130 (25%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPP-------PPFGMMRGP---PPPPRP---------PFGR 69
F PAP P+ G P R P P F GP P P P P
Sbjct: 1365 FSYPAPSPSLSSGGLP---RTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS 1421
Query: 70 PPFDPNMPPMPPPGGIPPPMGPPHLQR---------PPFMPPPMSSMPPPPGMMFPPGMP 120
P P+P P +P P+ P + R PP +P P++S PPP M PG P
Sbjct: 1422 PVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPP--MKRKPGRP 1479
Query: 121 PVTAPGTPAL 130
+ P +L
Sbjct: 1480 RRSPPSMLSL 1489
Score = 38.5 bits (88), Expect = 0.035
Identities = 44/162 (27%), Positives = 49/162 (30%), Gaps = 51/162 (31%)
Query: 16 PGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP------------PPP 63
P L +A LR + AP P + P PL PPP G P P
Sbjct: 1436 PLPLPLALPAVLRAQARAPTPLPPLL-PAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLV 1494
Query: 64 RPPFGRP--------PFDPNMPPMPPP------------GGIPPPMGPPHLQRPPFMPPP 103
RPP G P P P P GIP P PPP
Sbjct: 1495 RPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAP------------PPP 1542
Query: 104 MSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDG 145
+ PPPP PP PP P + W P G
Sbjct: 1543 LPPQPPPP----PP--PPPVEPTKLPFKELDNQWPSEAIPPG 1578
Score = 37.4 bits (85), Expect = 0.079
Identities = 34/197 (17%), Positives = 76/197 (38%), Gaps = 3/197 (1%)
Query: 183 VQAQAQAQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 241
V ++A+A + +++ ++ ++ +++ + ++ + + A+ + + + + + A+ +
Sbjct: 1103 VTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAG 1162
Query: 242 QVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTT 301
+ + A A GA + V T + P S + V P
Sbjct: 1163 PEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPP-LPVGVEEPAD 1221
Query: 302 QDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPV 361
+ P ++ + +P P A V+ P P+ P P+P +P
Sbjct: 1222 SREPPEEP-GLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP 1280
Query: 362 MVPPFRVPLPGMPIPLP 378
+PP R P P P P P
Sbjct: 1281 PLPPPRPPRPPSPPPEP 1297
Score = 37.0 bits (84), Expect = 0.10
Identities = 33/107 (30%), Positives = 39/107 (36%), Gaps = 34/107 (31%)
Query: 36 PNAVMRGPP-------PLMRPPPPFGMMRG----PPPPPRPPF----------------G 68
P R PP PL+RPP + R P P P F G
Sbjct: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG 1535
Query: 69 RPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPP----PMSSMPPPP 111
P P +PP PPP PPP+ P L PF P ++PP P
Sbjct: 1536 IPAPPPPLPPQPPPPPPPPPVEPTKL---PFKELDNQWPSEAIPPGP 1579
Score = 36.2 bits (82), Expect = 0.17
Identities = 49/182 (26%), Positives = 68/182 (37%), Gaps = 26/182 (14%)
Query: 430 TAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMET 489
TA+SE +E D T+ K + E E E E S +
Sbjct: 1081 TALSEASEKDEGDSD----EEETVSIVTSKAEATSSSESSESSEFESSSESSP------S 1130
Query: 490 EEEDPKEEPIKEIKEEPKEEEMTEEEKAA--------QKAKPVATAPIPGTPWCVVWTGD 541
ED +E +E +EE +EEEM EE A Q + A A PG P +
Sbjct: 1131 SSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALA--PGAPAVDSLGME 1188
Query: 542 ERVFFYN----PTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGM-EELKKLRHPTPTMLS 596
E V P R SM D P +G + +EPP + G+ +E L P P
Sbjct: 1189 EEVDIETEAVAPEERPSMLDEPPLPVG-VEEPADSREPPEEPGLSQEGAMLLSPEPPAKE 1247
Query: 597 IQ 598
++
Sbjct: 1248 VE 1249
Score = 35.4 bits (80), Expect = 0.30
Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 20/109 (18%)
Query: 37 NAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPP-PMGPPHL- 94
NA + PPP + P PP PPPPP + PF + P IPP P G +
Sbjct: 1533 NAGIPAPPPPLPPQPP-----PPPPPPPVEPTKLPF-KELDNQWPSEAIPPGPRGRDEVT 1586
Query: 95 --------QRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEE 135
R P+ PP + PP P +P P P E
Sbjct: 1587 EEYMELAKSRGPWRRPPKKRHED----LVPPAGSPELSPPQPLFRPRSE 1631
Score = 31.6 bits (70), Expect = 4.3
Identities = 45/253 (17%), Positives = 85/253 (33%), Gaps = 14/253 (5%)
Query: 160 TKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 219
+K + + SE + ++ + ++ + + A+ + + + + + A+ ++ A A
Sbjct: 1105 SKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAE-ESMASAGP 1163
Query: 220 QAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST---STSS 276
+ Q +A A A ++ +V + +A A P V + S
Sbjct: 1164 EDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSR 1223
Query: 277 STPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPH 336
P + A ++ + + P S + V P P+ P P
Sbjct: 1224 EPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP-PL 1282
Query: 337 PQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVAT 396
P PP P P+P T + P V P P L G K+ +T
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCG---------SLAKSQST 1333
Query: 397 TKTGVLPGMAPPI 409
PG PP+
Sbjct: 1334 ETVPATPGGEPPL 1346
Score = 30.4 bits (67), Expect = 9.6
Identities = 44/148 (29%), Positives = 58/148 (39%), Gaps = 29/148 (19%)
Query: 267 APAVSTSTSSSTPSSTTSTTTTATSVAQT--VSTPTTQDQTPSSAVSVATPTVSVSTPAP 324
+PAV T+ + +T + S+ +V T S P + Q SA TP + +TPAP
Sbjct: 333 SPAV-TAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAP 391
Query: 325 ----TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380
+P QT P H PP P+ TA AF FR P P P
Sbjct: 392 GFKSAFSPYQT-PVAH---FPPP-----PEEPTATAAFGARDSGEFR----RAPAPPP-- 436
Query: 381 AMMQIVSCPYVKTVATTKTGVLPGMAPP 408
P + +A K G PG PP
Sbjct: 437 -------LPPAEPLAKEKPGTPPGPPPP 457
Score = 30.4 bits (67), Expect = 9.6
Identities = 39/192 (20%), Positives = 82/192 (42%), Gaps = 6/192 (3%)
Query: 606 AIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPL-EARMK 664
++ EEQE EE E+E + ++ + DD+ D D E+ + E A E + ++ +
Sbjct: 1040 SLSEEQESTEE--EEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE 1097
Query: 665 QFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNK 724
+ ++ + + S+ E + + ++ ++V + + EEE +
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEES 1157
Query: 725 IMQA-KEDFKKMMEEAKFNPRA-TFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARK 782
+ A EDF++ EEA P A + D +A+ ++R ++ +E
Sbjct: 1158 MASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAP-EERPSMLDEPPLPVGV 1216
Query: 783 KEKEDSKTRGEK 794
+E DS+ E+
Sbjct: 1217 EEPADSREPPEE 1228
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 77.0 bits (188), Expect = 9e-14
Identities = 128/668 (19%), Positives = 273/668 (40%), Gaps = 153/668 (22%)
Query: 402 LPGMAPPIVPMIHPQVAIAASPATLAGATA---------VSEWTEYKTADGKTYYYNNRT 452
L G A ++ +H A A A + E T+ + A Y N T
Sbjct: 156 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 215
Query: 453 LESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMT 512
E EK +L+EK +L E K I+ + +E K E K + P+++
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQ--------LNVKELKRKLERAKLLL--PQQQLQA 265
Query: 513 EEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKII 572
E + ++ + V+ +W+R +
Sbjct: 266 EADHLGKELQSVSAK------------------LQAQVEENELWNR------------LN 295
Query: 573 QEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDD 632
Q+ K +E K IQ+W+ I+E++E + E ++E ++ ++ K
Sbjct: 296 QQQEEKMWRQEEK-----------IQEWE---EKIQEQEEKIRE--QEEKIREQEEKMRR 339
Query: 633 NKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDP 692
+++ EKE M + + E+ E +M++ ++M+ WEKE
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEK-----EEKMRRQEEMM----------WEKE-------- 376
Query: 693 RYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAA 752
K R+Q EE EK+ KI + +E KM E+ K E
Sbjct: 377 ------EKMRRQ----------EEMMWEKEEKIRELEE---KMHEQEKIR------EQEE 411
Query: 753 KHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQS 812
K ++ + + EK +++E A +++E + + EKI+ + +
Sbjct: 412 KRQEEEKIREQEKRQEQE--------AKMWRQEEKIREQEEKIR------------EQEK 451
Query: 813 RWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKI--AKNLDSEKEKELERQARIEASLR 870
+ + ++K+ + + + +E++++Q EKI + + +KEK E++ +I
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQE-EKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 871 EREREVQKARSEQTKEIDREREQHKREEAIQNFKALL--SDMVRSSDVSWSDTRRTLRKD 928
+ R+ +K R ++ K ++E + ++EE I+ + + + + + W + +R ++D
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 929 HRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDP 988
W + RE++EK++ + + +++E RQ +E WK+ +KI +++
Sbjct: 571 KMWRQEEKI-REQEEKVWRQEEKI---REQEEKRQEQEE-------KMWKQEEKIREQEE 619
Query: 989 RCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVE 1048
+ +K RE EE IR++ + + ++ + + + +K+ ++ + + E
Sbjct: 620 KI----QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
Query: 1049 KILQNDKR 1056
KI + +K+
Sbjct: 676 KIREQEKK 683
Score = 73.2 bits (178), Expect = 1e-12
Identities = 102/529 (19%), Positives = 232/529 (43%), Gaps = 90/529 (17%)
Query: 449 NNRTLESTW---EKPQELKEK-EKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE 504
N + E W EK QE +EK ++ EEKI+E ++ E+ M +EE E KE K
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE---KEEKM 351
Query: 505 EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIG 564
+EE M E+E+ ++ + + +W +E++ MW++ +
Sbjct: 352 RRQEEMMWEKEEKMRRQEEM------------MWEKEEKM----RRQEEMMWEKEEK--- 392
Query: 565 RADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVK 624
I+E K M E +K+R +K I+E+++ E+ E + +
Sbjct: 393 -------IRELEEK--MHEQEKIREQEEKRQEEEK-------IREQEKRQEQ--EAKMWR 434
Query: 625 AKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKE 684
+++ R+ + I +++ E K + I E R +Q ++M + E++
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ-EEMWRQ---------EEK 484
Query: 685 LHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEER-REKKNKIMQAKEDFKKMMEEAKFNP 743
+H E+++++ Q K +EE+ R+++ K+ + +E ++ E+ +
Sbjct: 485 IH--------------EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 744 RATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELL 803
+ + ++ ++ EKM ++E ++ E +++E+ED R E+ + E +
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEE----EKRQEQEDKMWRQEEKIREQEEKV 586
Query: 804 SNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKEL---- 859
+ + R + K + + + +K + +E+ ++ EKI + + +E+E
Sbjct: 587 WRQ--EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 860 --ERQARIEASLREREREVQKARSEQTKEIDREREQHKR----EEAIQNFKALLSDMVRS 913
E+ E + E+E ++Q+ ++ ++ REQ K+ EE I+ + ++ +
Sbjct: 645 QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ--- 701
Query: 914 SDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHI--EALTKKKREH 960
+ W + ++ + + R ++EK++ + + +K +EH
Sbjct: 702 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 76.6 bits (187), Expect = 1e-13
Identities = 115/551 (20%), Positives = 232/551 (42%), Gaps = 75/551 (13%)
Query: 450 NRTLESTWEKPQELKEKEK-----------LEEKIKEPIKEPSEEPLPMETEEEDPKE-- 496
N E W + +EL+E+EK EE+++E + E+ M +E+ +E
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Query: 497 ----EPIKEIKEEPK----EEEMTE-EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFY 547
E KE++E+ K EE+M E EEK ++ + + +W +ER++
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK------MWRQEERLWEQ 343
Query: 548 NPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAI 607
R D + D+ ++E + M E +K+ M ++ + +
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEER--MREQEKMWEQEEKMQEEERIREREKKM 401
Query: 608 KEEQELMEEINE-----DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEAR 662
+EE+E M E E +E + ++ K + + +KE E E +E I E +
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 663 MKQFKDMLLER---------GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTR 713
++ ++M + WE+E + + D + + +ER +++Q + R
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQE--EKMRDQEQKMWDQEER--MWEQDERLR 517
Query: 714 AEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALF 773
+EER ++ K+ Q +E KM EE K T + ++ + + E+M++RE
Sbjct: 518 EKEERMREQKKMWQQEE---KMREEKK-----TQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 774 NEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSS 833
E R++E E + + EK++ E + Q + K+ ++ E + D
Sbjct: 570 REEEEMMREQE-EKMQEQEEKMREQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 834 SMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQ----KARSEQTKEIDR 889
+E++ + EK+ + + E+E E+ E +RE+E ++Q K R ++ K +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ 686
Query: 890 EREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEH 949
E + ++EE ++ + M + W + ++ E EKE+ +
Sbjct: 687 EEKMREQEEKMRGQE---EKMWGQEEKMWGQEEKMWGQE---------EMREKEERIRDQ 734
Query: 950 IEALTKKKREH 960
E + ++ EH
Sbjct: 735 KEKMQERLPEH 745
Score = 76.3 bits (186), Expect = 2e-13
Identities = 114/631 (18%), Positives = 265/631 (41%), Gaps = 87/631 (13%)
Query: 432 VSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIK-EPSEEPLPMETE 490
+ E T+ + A Y N T E +K EL+EK +L E K I+ E +E
Sbjct: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERA 220
Query: 491 EEDPKEEPIKEIKEE--PKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYN 548
+ + ++EE +EEE+ E+EK +K + +W +ER+
Sbjct: 221 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE------------KMWRQEERL---- 264
Query: 549 PTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIK 608
R + R +K+ ++ K+ E+ K+LR + +K + ++
Sbjct: 265 ---------REQEGKMREQEEKMRRQ--EKRLREQEKELREQEKELREQKKLREQEEQMQ 313
Query: 609 EEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKD 668
E++E M E E + +K R + + + EK+ + + +E + + R+++ ++
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Query: 669 MLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQA 728
+ E+ WE+E K+ + R + K++ ++ R +EE+ +K+ + M
Sbjct: 374 RMREQE----KMWEQE-EKMQEEERI----REREKKMREEEETMREQEEKMQKQEENMWE 424
Query: 729 KEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARK---KEK 785
+E+ + + + + + ++ ++ EK++D+E ++ + R+ +E+
Sbjct: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 786 EDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 845
ED E+ D Q W + + E D R + + + Q E
Sbjct: 485 EDQMWEQEEKMRD----------QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
Query: 846 KIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKA 905
K+ +EK+ + Q + E+ RE ++ R + K + E ++EE +Q
Sbjct: 535 KM------REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE--- 585
Query: 906 LLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLL 965
+ + +++ WE ++ E++EK++ E E + +++ E Q
Sbjct: 586 -------------QEEKMREQEEKMWEQEEKMQ-EQEEKMW-EQEEKMWEQEEEDKMQEQ 630
Query: 966 DETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKE 1025
+E W++ +K+ +++ + + +K RE EE +R++ + + ++
Sbjct: 631 EE-------MMWEQEEKMQEQEEKMWE----QEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 1026 TKFITYRSKKLIQESDQHLKDVEKILQNDKR 1056
+ + + +K+ ++ ++ EK+ +++
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Score = 68.9 bits (167), Expect = 2e-11
Identities = 90/454 (19%), Positives = 190/454 (41%), Gaps = 75/454 (16%)
Query: 671 LERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAK- 729
L+R +SA STW K+ RY+ KER + + + E +KKN +Q K
Sbjct: 143 LQRALSAVSTWHKKAD------RYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL 196
Query: 730 --------------EDFKKMMEEAKF-----------------NPRATFSEFAAKHAKDS 758
++ K+ +E AKF E + ++
Sbjct: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256
Query: 759 RFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVK 818
++ E+++++E E R++EK + + ++++ EL L Q + +
Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQEKR-LREQEKELREQEKELREQKKLREQEEQMQEQ 315
Query: 819 DKV--ESDPRYKAVDSSSMRED-----LFKQYIEKIAKNLDSEKE--KELERQARIEASL 869
++ E + + + + R++ KQ E+ K D E+ ++ ER E +
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375
Query: 870 REREREVQKARSEQTKEIDREREQHKREEAI------QNFKALLSDMVRSSDVSWSDTRR 923
RE+E+ ++ Q +E RERE+ REE + + +M + W R
Sbjct: 376 REQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435
Query: 924 TLRKDHRWESGSLLEREEK-----------EKLFNEHIEALTKKK-REHFRQLLDETSAI 971
+K+ WE + E+EEK E+++ + + ++K RE Q+ ++ +
Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 972 --TLTSTWKEVKKIIKEDPRCIKFSS--SDRKKQREFEEYIRDKYITAKADFRT-----L 1022
W + +++ ++D R + ++KK + EE +R++ T + + +T
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 1023 LKETKFITYRSKKLIQESDQHLKDVEKILQNDKR 1056
++E + + R KK+ +E + + EK+ + +++
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
Length = 478
Score = 76.3 bits (186), Expect = 2e-13
Identities = 105/418 (25%), Positives = 148/418 (35%), Gaps = 91/418 (21%)
Query: 7 DGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPP 66
D S F P ++ Q P PP G PP + P +M G PP
Sbjct: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPP-----LMPGVPPLMP-- 172
Query: 67 FGRPPFDPNMPP-MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAP 125
G PP P MPP M P GG+ PP GP PP MP MPPP + PG+PP+T
Sbjct: 173 -GMPPVMPGMPPGMMPMGGMMPP-GP---GIPPLMPGMPPGMPPP---VPRPGIPPMTQA 224
Query: 126 GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185
+ P + N+ P A T +P K P+ + Q+
Sbjct: 225 QAVSAP-----GILNRPP--------APTATVPAPQPPVTK--------PLFPSAGQMGT 263
Query: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245
+ + A + +++ A ++A + AQAQA VQ
Sbjct: 264 PVTSSSTASSNSES-------------------------LSASSKALFPSTAQAQAAVQG 298
Query: 246 QVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQT 305
V + +T TT P P T S+ +++T+ +T A A S P T T
Sbjct: 299 PVGTDFKPLNSTPAT-TTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTT 357
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPP 365
S + P + + + P ++P+P A PPV
Sbjct: 358 --------------SATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV---- 399
Query: 366 FRVPLPGMPIPLPGVAMMQIVSCPYVKTVA-----TTKTGVLPGMAPPI---VPMIHP 415
P+ GM P PG+ Q + P G LPG PP PM+ P
Sbjct: 400 --GPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 455
Score = 53.9 bits (128), Expect = 8e-07
Identities = 53/244 (21%), Positives = 87/244 (35%), Gaps = 47/244 (19%)
Query: 333 PQPHPQTLPPAVPHSVPQPTTAIPAFPPVM--VPPFRVPLPGM----------------- 373
P P +PP +P +P +P PPVM +PP +P+ GM
Sbjct: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPG 208
Query: 374 ---PIPLPGVAMM---QIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLA 427
P+P PG+ M Q VS P + T +P PP+ + P +P T
Sbjct: 209 MPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVT-- 266
Query: 428 GATAVSEWTEYKTADGKTYYYNNRTLESTWEKP--QELKEKEKLEEKIKEPIKEP----S 481
++ S +E +A K + + ++ + P + K EP K +
Sbjct: 267 SSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYT 326
Query: 482 EEPLPMETEEEDPKEEPIKEIKEEP--------------KEEEMTEEEKAAQKAKPVATA 527
+ + +P I +P +E+++ EE+ AQ K
Sbjct: 327 QSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNL 386
Query: 528 PIPG 531
P PG
Sbjct: 387 PRPG 390
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/321 (23%), Positives = 114/321 (35%), Gaps = 46/321 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPP---PPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
P PPP GPP + PP + PP PPP P PP P+M P PPP +
Sbjct: 140 PPPPPGPA-PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP--VLEA 196
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMF-PPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
+ PPH P +P P +PP P + F P PPV AP PA + P G
Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256
Query: 148 YY-----YNARTRESAWTKPDGVKVIQQSEL--------------------TPMLAAQAQ 182
+ N R E+ P + TP+ +
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 183 VQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA---- 237
VQ AQ + + A +A ++ + +Q + + +A A A
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 238 -QAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--------SSSTPSSTTSTTTT 288
Q+Q+Q + A + P PAP + + ++ P+ T T +
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 289 ATSVAQTVSTPTTQDQTPSSA 309
++ + P + + T SSA
Sbjct: 437 SSPALKPKPNPPSPENTASSA 457
Score = 48.1 bits (113), Expect = 4e-05
Identities = 78/352 (22%), Positives = 112/352 (31%), Gaps = 45/352 (12%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
PPPPP P G PP D + PPGG P +P P S+ PPPP ++ P
Sbjct: 140 PPPPPGPAPG-PPQDIS----EPPGGSP-------------LPSPPSTAPPPPPLLLEPP 181
Query: 119 MPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLA 178
PP A P PP +E +P + + S T PD + L +
Sbjct: 182 PPPSMA---PPPPPV----LEALSPP------HTLSSPSIPTPPDFIP--PAPPLAFLAP 226
Query: 179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 238
V A A + + A QA+A + ++ A+ +
Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286
Query: 239 AQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST 298
A ++ V TP +S P + T + + +
Sbjct: 287 ALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI 346
Query: 299 PTTQDQTPSSAVSVATP-TVSVSTPA-PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIP 356
P A P + + PA P Q+ T PPA P P P
Sbjct: 347 RPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPP---- 402
Query: 357 AFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPP 408
+PP PLP PLP + KT ++ + P PP
Sbjct: 403 ------LPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP 448
Score = 43.5 bits (101), Expect = 0.001
Identities = 79/429 (18%), Positives = 133/429 (31%), Gaps = 42/429 (9%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP------PPRPPFGRPPFDPNMPPMPP--- 81
GP P P+ P + PPP + P PR G P+ P+PP
Sbjct: 289 GPNPEPHLTF---PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
Query: 82 --------PGGIPPPMGPPHLQRPPFMPPPMSSMP---------PPPGMMFPPGMPPVTA 124
P P P P L+ P + PPP PP PP+
Sbjct: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Query: 125 PGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQ 184
P P P + K + S KP ++ A+ A V
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT-----ASSAPVD 460
Query: 185 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQ 244
+ +Q + A ++ + + + A + + + + +
Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520
Query: 245 AQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTP--SSTTSTTTTATSVAQTVSTPTTQ 302
V +++G S+ T + AP+++ + P S T S + +S+ +
Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580
Query: 303 DQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM 362
+ PS P + + +P + LPP +P + A
Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640
Query: 363 VPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAAS 422
+PP P P +P A + + P T G P+ P AIA++
Sbjct: 641 IPPKATPEPA----IPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP--AIAST 694
Query: 423 PATLAGATA 431
TL T+
Sbjct: 695 ATTLPTTTS 703
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 32/203 (15%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVA 381
P P P Q + +P + P+ P + P P PP+++ P P P M P P V
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPP-------PPLLLEP--PPPPSMAPPPPPV- 193
Query: 382 MMQIVSCPYVKTVATTKTGVLPGMAPPIVPM--IHPQVAIAASPATLAGATAVSEWTEYK 439
++ +S P+ T+++ P PP P+ + P +PA A A+ + T
Sbjct: 194 -LEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250
Query: 440 TADGKTYY-----YNNRTLESTWEKPQELKEKEK-------LEEKIKEPIKEPSEEPLPM 487
G T + N R E+T P + K E + P P P+
Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPV 310
Query: 488 ETEEEDPKEEPIKEIKEEPKEEE 510
T P++E +E P++EE
Sbjct: 311 RT-----SSIPVQEAQEAPRKEE 328
Score = 41.6 bits (96), Expect = 0.004
Identities = 90/414 (21%), Positives = 134/414 (32%), Gaps = 75/414 (18%)
Query: 9 GESERFNPGELRMAQQQALRF-RGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
GE + P R+ Q Q+ R PPP + P P + PP PP PP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP-------APPLPP---- 412
Query: 68 GRPPFDPNMPPMPPPGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM------ 119
PP PP G P P L+ P P P ++ P P
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 120 --------------------PPVTAPGT------PALPPTEEI--WVENKTPDG---KVY 148
P AP + P LP E + TP G K
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 149 YYNARTRESA---WTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
++ T A T P V I Q TP + Q++ + +A+ + A+ +A+
Sbjct: 533 GGSSLTETEAAPSLTLP-SVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEAKPSI-G 587
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ + + + A ++ A+ + Q +A +G + P ++
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM-LGPAIPPKAT 646
Query: 266 PAPAV------------STSTSSSTPSSTTSTTTT---ATSVAQTVSTPTTQDQTPSSAV 310
P PA+ + +TP TS TT ATS ST TT T S +
Sbjct: 647 PEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM 706
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364
+ + P + V T Q + P Q + AFPP P
Sbjct: 707 AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 37.7 bits (86), Expect = 0.060
Identities = 59/266 (22%), Positives = 87/266 (32%), Gaps = 32/266 (12%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PAPP + PPP+ P PP P P R + PPGG+
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPP------APASPHTVGTR---------LFPPGGVTKW 258
Query: 89 MGPPHLQ----RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP-----TEEIWVE 139
L PP S P + P P +T P + +PP T I V+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQA 199
+ + S P + S++ P A + + +A A A +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL-- 376
Query: 200 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGAS 259
Q+Q+QA +A A A A + AQ A
Sbjct: 377 ---GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPC---AQKAAHPPAGF 430
Query: 260 TPTTSSPAPAVSTSTSSSTPSSTTST 285
T T S +PA+ + +P +T S+
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASS 456
Score = 35.0 bits (79), Expect = 0.39
Identities = 51/264 (19%), Positives = 81/264 (30%), Gaps = 58/264 (21%)
Query: 100 MPPPMSSMPPP----PGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTR 155
+PP +++ P P M P +PP P PA+PP +W T
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPPKATP-EPAIPPKATLW--------------PATP 662
Query: 156 ESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 215
A P TP+ A A
Sbjct: 663 PKATLGPATPLKATSGPTTPLKATSGPAIAST---------------------------- 694
Query: 216 QAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
A +Q A+ + Q + A + +QA G +P+ ++ P +S
Sbjct: 695 ---ATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS 751
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQP 335
++ P T+ + P + S V+V PT++ A PV+ P
Sbjct: 752 AAFPPKTSP----GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807
Query: 336 HPQTLPPAVPHSVPQPTTAIPAFP 359
PA P + QPT + P
Sbjct: 808 G----LPAKPPASAQPTDELLRHP 827
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/321 (23%), Positives = 114/321 (35%), Gaps = 46/321 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPP---PPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
P PPP GPP + PP + PP PPP P PP P+M P PPP +
Sbjct: 140 PPPPPGPA-PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP--VLEA 196
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMF-PPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
+ PPH P +P P +PP P + F P PPV AP PA + P G
Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256
Query: 148 YY-----YNARTRESAWTKPDGVKVIQQSEL--------------------TPMLAAQAQ 182
+ N R E+ P + TP+ +
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 183 VQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA---- 237
VQ AQ + + A +A ++ + +Q + + +A A A
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 238 -QAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--------SSSTPSSTTSTTTT 288
Q+Q+Q + A + P PAP + + ++ P+ T T +
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 289 ATSVAQTVSTPTTQDQTPSSA 309
++ + P + + T SSA
Sbjct: 437 SSPALKPKPNPPSPENTASSA 457
Score = 48.1 bits (113), Expect = 4e-05
Identities = 78/352 (22%), Positives = 112/352 (31%), Gaps = 45/352 (12%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
PPPPP P G PP D + PPGG P +P P S+ PPPP ++ P
Sbjct: 140 PPPPPGPAPG-PPQDIS----EPPGGSP-------------LPSPPSTAPPPPPLLLEPP 181
Query: 119 MPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLA 178
PP A P PP +E +P + + S T PD + L +
Sbjct: 182 PPPSMA---PPPPPV----LEALSPP------HTLSSPSIPTPPDFIP--PAPPLAFLAP 226
Query: 179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 238
V A A + + A QA+A + ++ A+ +
Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286
Query: 239 AQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST 298
A ++ V TP +S P + T + + +
Sbjct: 287 ALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI 346
Query: 299 PTTQDQTPSSAVSVATP-TVSVSTPA-PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIP 356
P A P + + PA P Q+ T PPA P P P
Sbjct: 347 RPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPP---- 402
Query: 357 AFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPP 408
+PP PLP PLP + KT ++ + P PP
Sbjct: 403 ------LPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP 448
Score = 43.5 bits (101), Expect = 0.001
Identities = 79/429 (18%), Positives = 133/429 (31%), Gaps = 42/429 (9%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP------PPRPPFGRPPFDPNMPPMPP--- 81
GP P P+ P + PPP + P PR G P+ P+PP
Sbjct: 289 GPNPEPHLTF---PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
Query: 82 --------PGGIPPPMGPPHLQRPPFMPPPMSSMP---------PPPGMMFPPGMPPVTA 124
P P P P L+ P + PPP PP PP+
Sbjct: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Query: 125 PGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQ 184
P P P + K + S KP ++ A+ A V
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT-----ASSAPVD 460
Query: 185 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQ 244
+ +Q + A ++ + + + A + + + + +
Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520
Query: 245 AQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTP--SSTTSTTTTATSVAQTVSTPTTQ 302
V +++G S+ T + AP+++ + P S T S + +S+ +
Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580
Query: 303 DQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM 362
+ PS P + + +P + LPP +P + A
Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640
Query: 363 VPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAAS 422
+PP P P +P A + + P T G P+ P AIA++
Sbjct: 641 IPPKATPEPA----IPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP--AIAST 694
Query: 423 PATLAGATA 431
TL T+
Sbjct: 695 ATTLPTTTS 703
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 32/203 (15%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVA 381
P P P Q + +P + P+ P + P P PP+++ P P P M P P V
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPP-------PPLLLEP--PPPPSMAPPPPPV- 193
Query: 382 MMQIVSCPYVKTVATTKTGVLPGMAPPIVPM--IHPQVAIAASPATLAGATAVSEWTEYK 439
++ +S P+ T+++ P PP P+ + P +PA A A+ + T
Sbjct: 194 -LEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250
Query: 440 TADGKTYY-----YNNRTLESTWEKPQELKEKEK-------LEEKIKEPIKEPSEEPLPM 487
G T + N R E+T P + K E + P P P+
Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPV 310
Query: 488 ETEEEDPKEEPIKEIKEEPKEEE 510
T P++E +E P++EE
Sbjct: 311 RT-----SSIPVQEAQEAPRKEE 328
Score = 41.6 bits (96), Expect = 0.004
Identities = 90/414 (21%), Positives = 134/414 (32%), Gaps = 75/414 (18%)
Query: 9 GESERFNPGELRMAQQQALRF-RGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
GE + P R+ Q Q+ R PPP + P P + PP PP PP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP-------APPLPP---- 412
Query: 68 GRPPFDPNMPPMPPPGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM------ 119
PP PP G P P L+ P P P ++ P P
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 120 --------------------PPVTAPGT------PALPPTEEI--WVENKTPDG---KVY 148
P AP + P LP E + TP G K
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 149 YYNARTRESA---WTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
++ T A T P V I Q TP + Q++ + +A+ + A+ +A+
Sbjct: 533 GGSSLTETEAAPSLTLP-SVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEAKPSI-G 587
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ + + + A ++ A+ + Q +A +G + P ++
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM-LGPAIPPKAT 646
Query: 266 PAPAV------------STSTSSSTPSSTTSTTTT---ATSVAQTVSTPTTQDQTPSSAV 310
P PA+ + +TP TS TT ATS ST TT T S +
Sbjct: 647 PEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM 706
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364
+ + P + V T Q + P Q + AFPP P
Sbjct: 707 AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 37.7 bits (86), Expect = 0.060
Identities = 59/266 (22%), Positives = 87/266 (32%), Gaps = 32/266 (12%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PAPP + PPP+ P PP P P R + PPGG+
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPP------APASPHTVGTR---------LFPPGGVTKW 258
Query: 89 MGPPHLQ----RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP-----TEEIWVE 139
L PP S P + P P +T P + +PP T I V+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQA 199
+ + S P + S++ P A + + +A A A +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL-- 376
Query: 200 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGAS 259
Q+Q+QA +A A A A + AQ A
Sbjct: 377 ---GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPC---AQKAAHPPAGF 430
Query: 260 TPTTSSPAPAVSTSTSSSTPSSTTST 285
T T S +PA+ + +P +T S+
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASS 456
Score = 35.0 bits (79), Expect = 0.39
Identities = 51/264 (19%), Positives = 81/264 (30%), Gaps = 58/264 (21%)
Query: 100 MPPPMSSMPPP----PGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTR 155
+PP +++ P P M P +PP P PA+PP +W T
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPPKATP-EPAIPPKATLW--------------PATP 662
Query: 156 ESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 215
A P TP+ A A
Sbjct: 663 PKATLGPATPLKATSGPTTPLKATSGPAIAST---------------------------- 694
Query: 216 QAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
A +Q A+ + Q + A + +QA G +P+ ++ P +S
Sbjct: 695 ---ATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS 751
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQP 335
++ P T+ + P + S V+V PT++ A PV+ P
Sbjct: 752 AAFPPKTSP----GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807
Query: 336 HPQTLPPAVPHSVPQPTTAIPAFP 359
PA P + QPT + P
Sbjct: 808 G----LPAKPPASAQPTDELLRHP 827
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/321 (23%), Positives = 114/321 (35%), Gaps = 46/321 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPP---PPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
P PPP GPP + PP + PP PPP P PP P+M P PPP +
Sbjct: 140 PPPPPGPA-PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP--VLEA 196
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMF-PPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
+ PPH P +P P +PP P + F P PPV AP PA + P G
Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256
Query: 148 YY-----YNARTRESAWTKPDGVKVIQQSEL--------------------TPMLAAQAQ 182
+ N R E+ P + TP+ +
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 183 VQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA---- 237
VQ AQ + + A +A ++ + +Q + + +A A A
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 238 -QAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--------SSSTPSSTTSTTTT 288
Q+Q+Q + A + P PAP + + ++ P+ T T +
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 289 ATSVAQTVSTPTTQDQTPSSA 309
++ + P + + T SSA
Sbjct: 437 SSPALKPKPNPPSPENTASSA 457
Score = 48.1 bits (113), Expect = 4e-05
Identities = 78/352 (22%), Positives = 112/352 (31%), Gaps = 45/352 (12%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
PPPPP P G PP D + PPGG P +P P S+ PPPP ++ P
Sbjct: 140 PPPPPGPAPG-PPQDIS----EPPGGSP-------------LPSPPSTAPPPPPLLLEPP 181
Query: 119 MPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLA 178
PP A P PP +E +P + + S T PD + L +
Sbjct: 182 PPPSMA---PPPPPV----LEALSPP------HTLSSPSIPTPPDFIP--PAPPLAFLAP 226
Query: 179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 238
V A A + + A QA+A + ++ A+ +
Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286
Query: 239 AQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST 298
A ++ V TP +S P + T + + +
Sbjct: 287 ALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI 346
Query: 299 PTTQDQTPSSAVSVATP-TVSVSTPA-PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIP 356
P A P + + PA P Q+ T PPA P P P
Sbjct: 347 RPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPP---- 402
Query: 357 AFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPP 408
+PP PLP PLP + KT ++ + P PP
Sbjct: 403 ------LPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP 448
Score = 43.5 bits (101), Expect = 0.001
Identities = 79/429 (18%), Positives = 133/429 (31%), Gaps = 42/429 (9%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP------PPRPPFGRPPFDPNMPPMPP--- 81
GP P P+ P + PPP + P PR G P+ P+PP
Sbjct: 289 GPNPEPHLTF---PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
Query: 82 --------PGGIPPPMGPPHLQRPPFMPPPMSSMP---------PPPGMMFPPGMPPVTA 124
P P P P L+ P + PPP PP PP+
Sbjct: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Query: 125 PGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQ 184
P P P + K + S KP ++ A+ A V
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT-----ASSAPVD 460
Query: 185 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQ 244
+ +Q + A ++ + + + A + + + + +
Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520
Query: 245 AQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTP--SSTTSTTTTATSVAQTVSTPTTQ 302
V +++G S+ T + AP+++ + P S T S + +S+ +
Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580
Query: 303 DQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM 362
+ PS P + + +P + LPP +P + A
Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640
Query: 363 VPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAAS 422
+PP P P +P A + + P T G P+ P AIA++
Sbjct: 641 IPPKATPEPA----IPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP--AIAST 694
Query: 423 PATLAGATA 431
TL T+
Sbjct: 695 ATTLPTTTS 703
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 32/203 (15%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVA 381
P P P Q + +P + P+ P + P P PP+++ P P P M P P V
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPP-------PPLLLEP--PPPPSMAPPPPPV- 193
Query: 382 MMQIVSCPYVKTVATTKTGVLPGMAPPIVPM--IHPQVAIAASPATLAGATAVSEWTEYK 439
++ +S P+ T+++ P PP P+ + P +PA A A+ + T
Sbjct: 194 -LEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250
Query: 440 TADGKTYY-----YNNRTLESTWEKPQELKEKEK-------LEEKIKEPIKEPSEEPLPM 487
G T + N R E+T P + K E + P P P+
Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPV 310
Query: 488 ETEEEDPKEEPIKEIKEEPKEEE 510
T P++E +E P++EE
Sbjct: 311 RT-----SSIPVQEAQEAPRKEE 328
Score = 41.6 bits (96), Expect = 0.004
Identities = 90/414 (21%), Positives = 134/414 (32%), Gaps = 75/414 (18%)
Query: 9 GESERFNPGELRMAQQQALRF-RGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
GE + P R+ Q Q+ R PPP + P P + PP PP PP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP-------APPLPP---- 412
Query: 68 GRPPFDPNMPPMPPPGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM------ 119
PP PP G P P L+ P P P ++ P P
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 120 --------------------PPVTAPGT------PALPPTEEI--WVENKTPDG---KVY 148
P AP + P LP E + TP G K
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 149 YYNARTRESA---WTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
++ T A T P V I Q TP + Q++ + +A+ + A+ +A+
Sbjct: 533 GGSSLTETEAAPSLTLP-SVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEAKPSI-G 587
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ + + + A ++ A+ + Q +A +G + P ++
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM-LGPAIPPKAT 646
Query: 266 PAPAV------------STSTSSSTPSSTTSTTTT---ATSVAQTVSTPTTQDQTPSSAV 310
P PA+ + +TP TS TT ATS ST TT T S +
Sbjct: 647 PEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM 706
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364
+ + P + V T Q + P Q + AFPP P
Sbjct: 707 AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 37.7 bits (86), Expect = 0.060
Identities = 59/266 (22%), Positives = 87/266 (32%), Gaps = 32/266 (12%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PAPP + PPP+ P PP P P R + PPGG+
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPP------APASPHTVGTR---------LFPPGGVTKW 258
Query: 89 MGPPHLQ----RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP-----TEEIWVE 139
L PP S P + P P +T P + +PP T I V+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQA 199
+ + S P + S++ P A + + +A A A +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL-- 376
Query: 200 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGAS 259
Q+Q+QA +A A A A + AQ A
Sbjct: 377 ---GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPC---AQKAAHPPAGF 430
Query: 260 TPTTSSPAPAVSTSTSSSTPSSTTST 285
T T S +PA+ + +P +T S+
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASS 456
Score = 35.0 bits (79), Expect = 0.39
Identities = 51/264 (19%), Positives = 81/264 (30%), Gaps = 58/264 (21%)
Query: 100 MPPPMSSMPPP----PGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTR 155
+PP +++ P P M P +PP P PA+PP +W T
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPPKATP-EPAIPPKATLW--------------PATP 662
Query: 156 ESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 215
A P TP+ A A
Sbjct: 663 PKATLGPATPLKATSGPTTPLKATSGPAIAST---------------------------- 694
Query: 216 QAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
A +Q A+ + Q + A + +QA G +P+ ++ P +S
Sbjct: 695 ---ATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS 751
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQP 335
++ P T+ + P + S V+V PT++ A PV+ P
Sbjct: 752 AAFPPKTSP----GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807
Query: 336 HPQTLPPAVPHSVPQPTTAIPAFP 359
PA P + QPT + P
Sbjct: 808 G----LPAKPPASAQPTDELLRHP 827
>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
Length = 494
Score = 75.9 bits (185), Expect = 2e-13
Identities = 102/400 (25%), Positives = 145/400 (36%), Gaps = 96/400 (24%)
Query: 44 PPLMRPP-PPFGMMRGPPP--PPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQR---- 96
PP+ +P PP G PP PP P G PP P MPP+ P G+PP + H QR
Sbjct: 140 PPMAQPGLPPVPGAPGMPPGIPPLMP-GVPPLMPGMPPVMP--GMPPGL---HHQRKYTQ 193
Query: 97 ----PPFMPPPMSSMPPPPGMM-----FPPGM-PPVTAPGTPALPPTEEI---WVENKTP 143
M P MPP PG+ PPGM PPV PG P + + + + N+ P
Sbjct: 194 SFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP 253
Query: 144 DGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQA 203
A T +P K P+ + Q+ + + A + +++
Sbjct: 254 --------APTATVPAPQPPVTK--------PLFPSAGQMGTPVTSSSTASSNSES---- 293
Query: 204 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTT 263
A ++A + AQAQA VQ V + +T TT
Sbjct: 294 ---------------------LSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPAT-TT 331
Query: 264 SSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPA 323
P P T S+ +++T+ +T A A S P T T S +
Sbjct: 332 EPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTT--------------SATS 377
Query: 324 PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMM 383
P + + + P ++P+P A PPV P+ GM P PG+
Sbjct: 378 KLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV------GPIGGMMPPQPGIPQQ 431
Query: 384 QIVSCPYVKTVA-----TTKTGVLPGMAPPI---VPMIHP 415
Q + P G LPG PP PM+ P
Sbjct: 432 QGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 471
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/89 (34%), Positives = 34/89 (38%), Gaps = 26/89 (29%)
Query: 57 RGPPPPPRPPFGRPPFDPNMPPMPPPGGIP---------PPMG----------------- 90
R P P + P G PP P MPP GIP PP G
Sbjct: 400 RNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM 459
Query: 91 PPHLQRPPFMPPPMSSMPPPPGMMFPPGM 119
PP+ Q PP +PP P PP M PP M
Sbjct: 460 PPYGQGPPMVPPYQGGPPRPPMGMRPPVM 488
Score = 44.7 bits (104), Expect = 5e-04
Identities = 53/260 (20%), Positives = 87/260 (33%), Gaps = 63/260 (24%)
Query: 333 PQPHPQTLPPAVPHSVPQPTTAIPAFPPVM--VPP----------------FRVPLPGM- 373
P P +PP +P +P +P PPVM +PP +P+ GM
Sbjct: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMM 208
Query: 374 -------------------PIPLPGVAMM---QIVSCPYVKTVATTKTGVLPGMAPPIVP 411
P+P PG+ M Q VS P + T +P PP+
Sbjct: 209 PPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK 268
Query: 412 MIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKP--QELKEKEKL 469
+ P +P T ++ S +E +A K + + ++ + P + K
Sbjct: 269 PLFPSAGQMGTPVT--SSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNST 326
Query: 470 EEKIKEPIKEP----SEEPLPMETEEEDPKEEPIKEIKEEP--------------KEEEM 511
EP K ++ + +P I +P +E++
Sbjct: 327 PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 386
Query: 512 TEEEKAAQKAKPVATAPIPG 531
+ EE+ AQ K P PG
Sbjct: 387 SLEERRAQLPKYQRNLPRPG 406
Score = 31.2 bits (69), Expect = 5.6
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 4/59 (6%)
Query: 349 PQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAP 407
PQP + P M P P+PG P PG+ + P V + V+PGM P
Sbjct: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLM----PGVPPLMPGMPPVMPGMPP 183
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 75.1 bits (183), Expect = 3e-13
Identities = 54/132 (40%), Positives = 61/132 (46%), Gaps = 30/132 (22%)
Query: 22 AQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNM----- 76
A + LR + P PPP + RG PP PPPP GPPPPP G PP P+
Sbjct: 267 AVKNELRRQAPPPPPPS--RGGPP---PPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAA 321
Query: 77 PPMPPP----GGIPPPMGPPHLQRPPFMPPPM------SSMPPPP------GMMFPPGMP 120
PP PPP +PPP PP+ PP PPP S PPPP G + PP P
Sbjct: 322 PPPPPPSRPSVAVPPP--PPNRMYPP--PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377
Query: 121 PVTAPGTPALPP 132
P P P PP
Sbjct: 378 PPPPPPGPPPPP 389
Score = 67.8 bits (164), Expect = 5e-11
Identities = 49/113 (43%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP--RPPFGRPPFDPNM--PPMPP----- 81
GP PPP A RG PP PPP PPPPP RP PP PN PP PP
Sbjct: 298 GPPPPP-ARGRGAPP---PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353
Query: 82 -PGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPT 133
P G PPP P L P PPP PPPP PP P + + G +P T
Sbjct: 354 APSG-PPPPPPSVLGVGPVAPPPP---PPPPPPPGPPPPPGLPSDGDHQVPTT 402
Score = 63.9 bits (154), Expect = 8e-10
Identities = 43/112 (38%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 37 NAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQR 96
N + R PP PPPP PPPPP G PP PP G PPP
Sbjct: 270 NELRRQAPP---PPPPSRGGPPPPPPPPHNSGPPP-----PPARGRGAPPPPPSRAPTAA 321
Query: 97 PPFMPPPMSSM---PPPPGMMFPPGMP--PVTAPGTPALPPTEEIWVENKTP 143
PP PP S+ PPPP M+PP P P +AP P PP + V P
Sbjct: 322 PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373
Score = 38.5 bits (88), Expect = 0.035
Identities = 34/131 (25%), Positives = 44/131 (33%), Gaps = 9/131 (6%)
Query: 247 VQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTT---STTTTATSVAQTVSTPTTQD 303
V+ +++ QA P+ P P +S P S A T + P
Sbjct: 268 VKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPP 327
Query: 304 QTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMV 363
PS AV P P P +P P PP P + A P PP
Sbjct: 328 SRPSVAVPPPPPNRMYPPPPPA------LPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP 381
Query: 364 PPFRVPLPGMP 374
PP P PG+P
Sbjct: 382 PPGPPPPPGLP 392
Score = 38.5 bits (88), Expect = 0.035
Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 15/84 (17%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL----PPAVPHSVPQ-----PTTAIP 356
PS A + A P P P + P VP P P + PPA+P S P P + +
Sbjct: 314 PSRAPTAAPP------PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLG 367
Query: 357 AFPPVMVPPFRVPLPGMPIPLPGV 380
P PP P P P P PG+
Sbjct: 368 VGPVAPPPPPPPPPPPGPPPPPGL 391
Score = 35.0 bits (79), Expect = 0.39
Identities = 19/50 (38%), Positives = 20/50 (40%)
Query: 83 GGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
GG+ Q PP PP PPPP G PP A G A PP
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPP 312
Score = 33.1 bits (74), Expect = 1.5
Identities = 27/78 (34%), Positives = 33/78 (42%), Gaps = 8/78 (10%)
Query: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVP--QPTTAIPAFPP-VMVPPFRVPLP----- 371
S P P + P P P P A P P +P+ A+P PP M PP LP
Sbjct: 297 SGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPS 356
Query: 372 GMPIPLPGVAMMQIVSCP 389
G P P P V + V+ P
Sbjct: 357 GPPPPPPSVLGVGPVAPP 374
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 74.3 bits (181), Expect = 6e-13
Identities = 45/104 (43%), Positives = 54/104 (51%), Gaps = 15/104 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN---MPPMPPPGGIPPP 88
PAPP ++ GPP + RPPPP +M G PP P P PP P +PPMPP G P P
Sbjct: 218 PAPP--SLPAGPPGVKRPPPP--LMNGLPPRPPLPESLPPPPPGGLPLPPMPPTG--PAP 271
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM---PPVTAPGTPA 129
GPP PP +PPP + PP ++ PP PP PA
Sbjct: 272 SGPP---GPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPA 312
Score = 48.1 bits (113), Expect = 4e-05
Identities = 40/118 (33%), Positives = 45/118 (38%), Gaps = 19/118 (16%)
Query: 32 PAPPPNAVM------RGPPPLMRP-----PPPFGMMRGPPPPPRPPFG--RPPFDPNMPP 78
P PPP + GP P P PPP + P P PP PP PP
Sbjct: 252 PPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPP 311
Query: 79 M----PPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFP-PGMPPVTAPGTPALP 131
PP G+ PP H P PP PP PG+ P PG+ P APG P
Sbjct: 312 APGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP-PAPGVHPPP 368
Score = 48.1 bits (113), Expect = 4e-05
Identities = 38/111 (34%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 32 PAP---PPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPG----- 83
PAP PP + + P P + PP P P P P PP P + P P G
Sbjct: 318 PAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPA-PGVHPPPSAGVHPQA 376
Query: 84 -GIPPPMGPPHLQRPPFMPPPMSSMPPPPGMM-FPPGMPPVTAPGTPALPP 132
G+ P H Q P PP P PG+ PPG+ P +APG PP
Sbjct: 377 PGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHP-SAPGVHPQPP 426
Score = 47.4 bits (111), Expect = 8e-05
Identities = 37/110 (33%), Positives = 44/110 (40%), Gaps = 10/110 (9%)
Query: 32 PAP---PPNAVMRGPPPLMRPPPPFGMM-RGPPPPPRPPFGRPPFDPNMPPMP-----PP 82
PAP PP + P P + PPP G+ + P P P P PP P P
Sbjct: 346 PAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAP 405
Query: 83 GGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
G P P G H P P P P PG+ P MPP+ P P+ P
Sbjct: 406 GVHPQPPGV-HPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGP 454
Score = 43.9 bits (102), Expect = 8e-04
Identities = 33/102 (32%), Positives = 42/102 (41%), Gaps = 5/102 (4%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMG 90
G PPP+A + P + P P + P P P G P P + P PP G+ P
Sbjct: 363 GVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAP-GMHPQAPGVHPQPP--GVHPSAP 419
Query: 91 PPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
H Q P P PP P M P PP+ + G +PP
Sbjct: 420 GVHPQPPGVHPSNPGVHPPTP--MPPMLRPPLPSEGPGNIPP 459
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/86 (37%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPP------PGGI 85
PA P A P + PP P + P P+PP G P P + P PP PG
Sbjct: 384 PAVHPQA------PGVHPPAPGMHPQAPGVHPQPP-GVHPSAPGVHPQPPGVHPSNPGVH 436
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPPPP 111
PP PP L RPP ++PPPP
Sbjct: 437 PPTPMPPML-RPPLPSEGPGNIPPPP 461
Score = 42.7 bits (99), Expect = 0.002
Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 7/113 (6%)
Query: 318 SVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPP---FRVPLPGMP 374
S+ P P P+ +P P P P +P P + PV+ PP P PG+
Sbjct: 250 SLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVH 309
Query: 375 IPLPGVAMMQIVSCPYVKTVATTKTGV---LPGMAPPIVPMIHPQVAIAASPA 424
P PGV P V GV PG+ PP P +HP PA
Sbjct: 310 PPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPP-APGVHPPAPGVHPPA 361
Score = 38.1 bits (87), Expect = 0.046
Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 19/131 (14%)
Query: 299 PTTQDQTPSSAVSVATPTVSVSTPAPTATPV-QTVPQPHPQTLP-PAVPHSVPQPTTAIP 356
P P+ V P + P P+ +++P P P LP P +P + P P+ P
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSG--P 274
Query: 357 AFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGV---LPGMAPPIVPMI 413
PP + P P PG+ P P V P V GV PG+ PP P +
Sbjct: 275 PGPPQLPP----PAPGVHPPAP-------VVHPPASGVHPPAPGVHPPAPGVHPP-APGV 322
Query: 414 HPQVAIAASPA 424
HP + PA
Sbjct: 323 HPPTSGVHPPA 333
Score = 38.1 bits (87), Expect = 0.046
Identities = 51/171 (29%), Positives = 58/171 (33%), Gaps = 24/171 (14%)
Query: 261 PTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVS 320
P PAP V S P + A V P P+S V P V
Sbjct: 285 PGVHPPAPVVHPPASGVHPPAPG-----VHPPAPGVHPPAPGVHPPTSGVHPPAP--GVH 337
Query: 321 TPAP-TATPVQTVPQPHPQTLPPAVPHSVPQPTTAI--------PAFPPV--MVPPFRVP 369
PAP P V P P PPA P P P+ + PA P V P P
Sbjct: 338 PPAPGVHPPAPGVHPPAPGVHPPA-PGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPP 396
Query: 370 LPGMPIPLPGVAMMQIVSCPYVKTVATTKTGV---LPGMAP--PIVPMIHP 415
PGM PGV P V GV PG+ P P+ PM+ P
Sbjct: 397 APGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRP 447
Score = 37.0 bits (84), Expect = 0.10
Identities = 33/127 (25%), Positives = 40/127 (31%), Gaps = 13/127 (10%)
Query: 253 AQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSV 312
A V P PAP V P + A V + P Q P
Sbjct: 340 APGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHP--AAPAVHPQAPG----- 392
Query: 313 ATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPG 372
V PAP P P P + P+ P PQP P+ P V P P+
Sbjct: 393 ------VHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLR 446
Query: 373 MPIPLPG 379
P+P G
Sbjct: 447 PPLPSEG 453
Score = 32.3 bits (72), Expect = 2.5
Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 15/94 (15%)
Query: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVM--VPPFRVPLP-GMPIPLPGVAMMQIVSCPYV 391
P P +LP A P V +P PP+M +PP R PLP +P P PG + P
Sbjct: 218 PAPPSLP-AGPPGVKRPP------PPLMNGLPP-RPPLPESLPPPPPGGLPLP----PMP 265
Query: 392 KTVATTKTGVLPGMAPPIVPMIHPQVAIAASPAT 425
T P PP P +HP + PA+
Sbjct: 266 PTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPAS 299
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/58 (37%), Positives = 23/58 (39%), Gaps = 7/58 (12%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGP---PPPPRPPFGRPPFDPNMP---PMPPP 82
G P P V P + P PP P PP P PP RPP P P PPP
Sbjct: 406 GVHPQPPGVHPSAPGV-HPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 73.9 bits (180), Expect = 8e-13
Identities = 61/217 (28%), Positives = 94/217 (43%), Gaps = 10/217 (4%)
Query: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
AQ AQ Q Q Q Q+ AQ + Q Q + Q Q + ++AQ ++ Q AQ+Q Q
Sbjct: 2273 AQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ 2332
Query: 241 AQVQAQVQAQVQAQA---VGASTPTTSSPAPAVSTSTSSSTP-SSTTSTTTTATSVAQTV 296
+ VQ Q +VQ+ + + STP+ SP T++S P T+ S Q
Sbjct: 2333 SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQ 2392
Query: 297 STPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIP 356
S P Q T + + V+VS+P + P + QP PQ + AVP + Q +
Sbjct: 2393 SQPQVQSSTQTLSSGQTLNQVTVSSP---SRPQLQIQQPQPQVI--AVP-QLQQQVQVLS 2446
Query: 357 AFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKT 393
+V + G+P + +QI V+T
Sbjct: 2447 QIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQT 2483
Score = 54.7 bits (130), Expect = 5e-07
Identities = 60/255 (23%), Positives = 85/255 (33%), Gaps = 22/255 (8%)
Query: 51 PPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPP 110
PP P +P +P P P P P +Q + + S P
Sbjct: 2256 PPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP 2315
Query: 111 PGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQ 170
P V A P + V ++P R R S P + QQ
Sbjct: 2316 THAQ--SSKPQVAAQSQPQSNVQGQSPVRVQSPS------QTRIRPST---PSQLSPGQQ 2364
Query: 171 SELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA--------- 221
S++ + +Q Q +Q Q Q+Q Q Q+ Q + Q Q
Sbjct: 2365 SQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQ 2424
Query: 222 --QAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTP 279
Q Q Q A Q Q Q Q +Q+Q+QV AQ+QAQ G + S++ T
Sbjct: 2425 IQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTH 2484
Query: 280 SSTTSTTTTATSVAQ 294
T A SV +
Sbjct: 2485 QIQNVVTVQAASVQE 2499
Score = 43.9 bits (102), Expect = 8e-04
Identities = 116/632 (18%), Positives = 222/632 (35%), Gaps = 102/632 (16%)
Query: 174 TPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA-----QAQAQ 228
TP + + + Q+ A + Q AQ Q Q Q Q Q
Sbjct: 2115 TPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQ 2174
Query: 229 AQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTT 288
Q Q Q + Q +QA A+ T P +T+T++ST ++T STT
Sbjct: 2175 TTGQLQLIPQGVTVLPGPGQQLMQA-AMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA 2233
Query: 289 ATSVA-QTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHS 347
T Q+ +P Q + + +V + P PQP Q PA P
Sbjct: 2234 GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQP-- 2291
Query: 348 VPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAP 407
++ + P V+T T + V P
Sbjct: 2292 ------------------------------------EVQTQPEVQTQTTVSSHVPSEAQP 2315
Query: 408 PIVPMIHPQVAIAASP-ATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEK 466
PQVA + P + + G + V + +T R ST P +L
Sbjct: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQT----------RIRPST---PSQLSPG 2362
Query: 467 EKLEEKIKEPIKEPSEEPLPME--TEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPV 524
++ + ++ + +P+P++ T + P + + + +P+ + T+ + Q V
Sbjct: 2363 QQSQ------VQTTTSQPIPIQPHTSLQIPSQ---GQPQSQPQVQSSTQTLSSGQTLNQV 2413
Query: 525 ATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEEL 584
T P P + +V + + ++ + + Q + G+ +
Sbjct: 2414 -TVSSPSRPQLQIQQPQPQVI------AVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQ 2466
Query: 585 KKLRHPTPTMLS--IQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEA 642
KL+ P S +Q Q + + E++ + ++ +++K+ + E
Sbjct: 2467 IKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKK-----QQQIEI 2521
Query: 643 AMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKER 702
E ++A+ + I+ + MK + + + + E+E ++ R ++ N +
Sbjct: 2522 KREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQ-----RMIVCN-QVM 2575
Query: 703 KQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKA 762
K + D+ K EE++ KK K ++ E + K S KH + R
Sbjct: 2576 KYILDKIDK---EEKQAAKKRKREESVEQKRSKQNATK------LSALLFKHKEQLR--- 2623
Query: 763 IEKMKDREALFNEFVAAARKKEKEDSKTRGEK 794
E +K R L + +++ K D K + EK
Sbjct: 2624 AEILKKRALLDKDLQIEVQEELKRDLKIKKEK 2655
Score = 36.6 bits (83), Expect = 0.13
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 17/137 (12%)
Query: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
+ +A A+ + +AQA Q QA+ +++ Q + ++ TTS+ +PA +
Sbjct: 1896 EIRAFAERVEKEKAQAVEQ-QAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPI 1954
Query: 278 TPSSTTST----TTTATSVA-----------QTVSTPTTQDQTPSSAVSVATPTVSVSTP 322
+ S TT T TT S A QT +T Q Q+ S V V + + P
Sbjct: 1955 SGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGI-IP 2013
Query: 323 APTATPVQTVPQPHPQT 339
+ T T QT P+T
Sbjct: 2014 SSTGTSQQTFTSFQPRT 2030
Score = 32.7 bits (73), Expect = 1.9
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
Query: 307 SSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPA 357
++AV+ P V+ + PAP A P P P P PPAV H+ T +PA
Sbjct: 2663 ATAVAAPCPPVTPAPPAPPAPP----PSPPP---PPAVQHTGLLSTPTLPA 2706
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 73.9 bits (180), Expect = 8e-13
Identities = 118/552 (21%), Positives = 179/552 (32%), Gaps = 61/552 (11%)
Query: 20 RMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPM 79
R +QA RG + P+ PP+ +P P G PP +P + P PP
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTP------GKPPAQQPGHEKSQPGPAKPPA 333
Query: 80 PPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVE 139
P G P P +PP PP + PP P PP G+ P +E+
Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTK---PPAQPLGPAKPPAQQTGSEK-PSSEQ---- 385
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPM-LAAQAQVQAQAQAQAQAQAQAQ 198
P K ++ +P K Q TP LA Q +Q+ A+A + Q
Sbjct: 386 ---PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 199 ----AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQ 254
+ AQ + AQ + +Q A+ Q A+ Q A+ +Q
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 255 AVGASTPTTSSPAPAV-------STSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPS 307
G++ P P PA ST S P S + + + T
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 308 SAVSVATPTVSVSTPAPTA--TPVQTVPQPHPQTLPPAVPHSVPQPT--------TAIPA 357
S + PTVS S P + P P + L VP T ++
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 358 FPP-----------VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMA 406
F P + + L G P+P ++ + P T A +K+ P
Sbjct: 623 FNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT 682
Query: 407 PPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEK 466
P P+ ++ +P V + T + + K + KP KE
Sbjct: 683 SPKKDAA-PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA---KQPPEADSLSKPAPPKEP 738
Query: 467 EKLEEKIKEPIKEPSEEPLPMETEEED-------PKEEPIKEIKEEPKEEEMTEEEKAAQ 519
E+ K P+ + + M D + I K + + EE T
Sbjct: 739 SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD 798
Query: 520 KAKPVATAPIPG 531
AKP + P G
Sbjct: 799 SAKPSQSFPPTG 810
Score = 64.3 bits (155), Expect = 6e-10
Identities = 203/1057 (19%), Positives = 375/1057 (35%), Gaps = 149/1057 (14%)
Query: 33 APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92
AP P++ P P ++ P P+P P D P P P PP
Sbjct: 651 APVPSS----PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA--APKQDLSKAPEPKKPP 704
Query: 93 HLQRPPFM---PPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVEN-KTPDGKVY 148
L + P + P + PP + P P P P+ + + K P
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK--EPSVPSEQDKAPVADDKPKQPKMVKP 762
Query: 149 YYNARTRESAWTKPD--GVKVIQQSE--LTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQ 204
+ + SA TKPD KV Q+E TP L + +Q+ + + ++A
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT-GEKVSPFDSKAI 821
Query: 205 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTS 264
+ + ++ + ++++ Q Q + + +AQ + + + G+ TP
Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
Query: 265 SPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAP 324
P + T +P + + ++ P +Q TP V+ S +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 325 TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQ 384
+ + T QP PHS P P + P P P G
Sbjct: 942 ASNLISTAGQPG--------PHSQSGPG----------APMKQAPAPSQPPTSQG----- 978
Query: 385 IVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGK 444
P T G APP P +I T A A +E E K
Sbjct: 979 ----PPKST----------GQAPPA-----PAKSIPVKKETKAPA---AEKLEPKAEQAP 1016
Query: 445 TYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE 504
T RT T +KP +K+ + L EP + LP + E+ E K
Sbjct: 1017 TV---KRT--ETEKKPPPIKDSKSL-------TAEPQKAVLPTKLEKSPKPESTCPLCKT 1064
Query: 505 EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDE-RVFFYNPT---TRLSMWDRPD 560
E + + P C + +NPT T + W +
Sbjct: 1065 ELN----------------IGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLN 1108
Query: 561 DLIGRA---DVDKIIQEPPHKKGME--------ELKKLRHPTPTMLSIQKWQFSMSAIKE 609
RA + I + PP G + E + P + + K Q +
Sbjct: 1109 CQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEA 1168
Query: 610 EQELMEEINED------EPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARM 663
E+ ++E++ E P+ +K++++K ++ +K +A++ + E+ ++P E ++
Sbjct: 1169 EKVILEKVKETLSMEKIPPMVTTDQKQEESK-LEKDKASALQEKKPLPEEKKLIPEEEKI 1227
Query: 664 K-QFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEE--ERRE 720
+ + K LLE E K++ P P+E+K + AEE E R
Sbjct: 1228 RSEEKKPLLEEKKPT-----PEDKKLL--PEAKTSAPEEQKHDLLKSQVQIAEEKLEGRV 1280
Query: 721 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDR--EALFNEFVA 778
+ + K+ KM P++ E D K I++ A ++
Sbjct: 1281 APKTVQEGKQPQTKMEGLPSGTPQSLPKE------DDKTTKTIKEQPQPPCTAKPDQVEP 1334
Query: 779 AARKKEKEDSK---TRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSM 835
K EKED K + ++ KS + LS+ S S + + P + +
Sbjct: 1335 GKEKTEKEDDKSDTSSSQQPKSP--QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGL 1392
Query: 836 REDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHK 895
++D F Q + + ++ E + +AS E+ +K + + EQ K
Sbjct: 1393 KKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSP-----EQPK 1447
Query: 896 REEAIQNFKALLSDMVRSSDVSWSDTRR--TLRKDHRWESGSLLEREEKEKLFNEHIEAL 953
+E Q+ L + ++ S R T +KD + + S + +EK +E ++ +
Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEK----SEFVDDI 1503
Query: 954 TKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYI 1013
T ++ + ++E+S + + ++ ++ D + E E++IR + I
Sbjct: 1504 TTRREPY--DSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561
Query: 1014 TAKAD-FRTLLKETKFITYRSKKLIQESDQHLKDVEK 1049
AD + ++ +FI + K++ ++ K+ K
Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598
Score = 58.9 bits (141), Expect = 3e-08
Identities = 90/365 (24%), Positives = 114/365 (31%), Gaps = 70/365 (19%)
Query: 36 PNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPP----MPPPGGIPPPMGP 91
P +++ PP +PP P +GP P G P + P PPG P GP
Sbjct: 203 PEGIIK-PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGP 261
Query: 92 PH----------LQRPPFMPPPM--------SSMPPPPGMMFPPGMPPVTAPGTPALPPT 133
LQR P S P P P PP+ P TP PP
Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS----PSKPPIQQP-TPGKPPA 316
Query: 134 EEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ-AQVQAQAQAQAQ 192
++ E P KP Q S LT LA Q V+ Q
Sbjct: 317 QQPGHEKSQPGP--------------AKPPA----QPSGLTKPLAQQPGTVKPPVQPPGT 358
Query: 193 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQ 252
+ AQ A+ AQ Q ++ + Q +A AQ + Q A+
Sbjct: 359 TKPPAQPLGPAKPPAQ-------QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 253 AQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSV 312
Q VG P P +P+ T T P Q ++
Sbjct: 412 TQQVGTPKPLAQQP--------GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
Query: 313 ATPTVSVS-TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP 371
PT S P P P Q QP P PP P S P+ P PP + P P
Sbjct: 464 TGPTKPPSQLPGPAKPPPQ---QPGPAKPPPQQPGSAKPPSQQ----PGSTKPPPQQPGP 516
Query: 372 GMPIP 376
P P
Sbjct: 517 AKPSP 521
Score = 48.1 bits (113), Expect = 4e-05
Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 60 PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM 119
P PRP F D + P PPP PPP PP PP +PPP S P + P
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP----TILPKKK 2442
Query: 120 PPVTAPGTPALP 131
V +P T A P
Sbjct: 2443 LTVASPVTTATP 2454
Score = 42.7 bits (99), Expect = 0.002
Identities = 103/500 (20%), Positives = 159/500 (31%), Gaps = 64/500 (12%)
Query: 81 PPGGIPPPMGP-PHLQRPPFM----PPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEE 135
P G +PP P + R + PP S PP PG PG+ T+
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRT--------TDT 118
Query: 136 IWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQ----SELTPMLAAQAQVQAQAQAQA 191
E K P + + +S + K SE+ + A + V
Sbjct: 119 FRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 192 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQV 251
+ ++A + + Q Q + Q + + + Q Q Q Q + +Q
Sbjct: 179 ISDSEASQEETTKKQKVVQKE-QGKPEGIIKPPLQQQPPKPIPKQ---QGPGRDPLQQDG 234
Query: 252 QAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQ-------DQ 304
+++ + P P T P+ T T + + S P T+ +
Sbjct: 235 TPKSISSQQPEKIKSQPP-GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293
Query: 305 TPSSAVSVATPTVSVSTPA--PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAF--PP 360
S S + P + TP P P QP P PPA P + +P P PP
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 361 VMVPPFRVPLPGMPIPLPGVAMMQIVS------CPYVKTVA----TTKT-GVLPGMAPPI 409
V PP P P+ Q S P K +A KT PG A P
Sbjct: 353 VQ-PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 410 VPMIHPQVAIA-----ASPATLAGATAV-------SEWTEYKTADGKTYYYNNRTLESTW 457
+ +A SPA G T + + GKT +
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 458 EKPQELKEKEKLEEKIKEPIKEPSEEPLPME----TEEEDPKEEPIKEIKEEPKEEEMTE 513
+ P K + K P ++P P + T+ + P K ++P +
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 514 EEKAAQKAKPVATAPIPGTP 533
++ + AKP A P P P
Sbjct: 532 QQPGS--AKPSAQQPSPAKP 549
Score = 38.1 bits (87), Expect = 0.046
Identities = 23/63 (36%), Positives = 25/63 (39%), Gaps = 2/63 (3%)
Query: 72 FDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPM--SSMPPPPGMMFPPGMPPVTAPGTPA 129
F P P G P P RP F + S+ PPPP PP PP P P
Sbjct: 2367 FGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
Query: 130 LPP 132
LPP
Sbjct: 2427 LPP 2429
Score = 35.4 bits (80), Expect = 0.30
Identities = 87/462 (18%), Positives = 171/462 (37%), Gaps = 58/462 (12%)
Query: 454 ESTWEKPQELKEKEK-----LEEKIKEPIKEPSEEPL-PMETEEEDPKEEPIKEIKEEPK 507
ES+ P +L + E LE + E SE+ P E E PK++ + E
Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459
Query: 508 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 567
E ++EEE + + T + D + + + DD+ R +
Sbjct: 1460 EITISEEEIKESQEERKDT-----------FKKDSQQDIPSSKDHKEKSEFVDDITTRRE 1508
Query: 568 VDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW--QFSMSAIKEEQELMEEINEDEPVKA 625
++E + ++ R + S ++ + S + +EE + ++I E +
Sbjct: 1509 PYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADED 1568
Query: 626 KKRKRDDN------KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFS 679
DD K+I S E+ + E K + + R+ + ++
Sbjct: 1569 ASGSEDDEFIRNQLKEISSSTESQKKEETKG-KGKITAGKHRRLTRKSSTSIDEDAGRRH 1627
Query: 680 TWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEA 739
+W E + FD+ + + E + ++ +++ + +
Sbjct: 1628 SWHDE-----------------DDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTI 1670
Query: 740 KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDF 799
+ N S A K++ +S K D E E + ED ++RGE S
Sbjct: 1671 ELN-----STIADKYSAESSQKKTSLYFDEEP---ELEMESLTDSPED-RSRGEGSSS-- 1719
Query: 800 FELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKEL 859
S S + S + + +S P +K +S R+ + + + DS +E+EL
Sbjct: 1720 LHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEEL 1779
Query: 860 -ERQARIEASLREREREVQKARS---EQTKEIDREREQHKRE 897
E + ++ ++RE E Q+ +S + K+ D R Q +RE
Sbjct: 1780 REEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRE 1821
Score = 31.6 bits (70), Expect = 4.3
Identities = 38/154 (24%), Positives = 54/154 (35%), Gaps = 26/154 (16%)
Query: 273 STSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT-------------VSV 319
S+ + P +TT TS +T Q PS + SV++ +S
Sbjct: 2345 SSVIALPMKEQLSTTYFTS-GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISA 2403
Query: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPF--RVPLPGMPIPL 377
P P P P P P PP P + P+P T +P + P PL L
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP-TILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 378 PGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVP 411
A+++ P + T APP VP
Sbjct: 2463 ETTAVLRSNGLPVTRICTT---------APPPVP 2487
Score = 31.6 bits (70), Expect = 4.3
Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 20/110 (18%)
Query: 261 PTTSSPAPA--------VSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQT------P 306
P +SP P V++ +++TP TT T+V ++ P T+ T P
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 307 SSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIP 356
S+ + V P P+ P+ P+ + P +P + +PT P
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIA------PKPVIPQLPTTTQKPTDIHP 2531
Score = 31.6 bits (70), Expect = 4.3
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 214 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV-----------GASTPT 262
Q + + QAQ + + AQ Q Q + Q+Q Q+ Q++ Q + G ++P
Sbjct: 3270 QQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYNYDPSGTASPQ 3329
Query: 263 TSSPAPAVSTSTSSSTPS---STTSTTTTATSVAQTVSTPTTQ 302
T++ + ++ S +T TTTA++V + P +Q
Sbjct: 3330 TTTEQAILEGQYAALEGSQFWATEDATTTASAVV-AIEIPQSQ 3371
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 73.9 bits (180), Expect = 8e-13
Identities = 118/552 (21%), Positives = 179/552 (32%), Gaps = 61/552 (11%)
Query: 20 RMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPM 79
R +QA RG + P+ PP+ +P P G PP +P + P PP
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTP------GKPPAQQPGHEKSQPGPAKPPA 333
Query: 80 PPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVE 139
P G P P +PP PP + PP P PP G+ P +E+
Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTK---PPAQPLGPAKPPAQQTGSEK-PSSEQ---- 385
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPM-LAAQAQVQAQAQAQAQAQAQAQ 198
P K ++ +P K Q TP LA Q +Q+ A+A + Q
Sbjct: 386 ---PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 199 ----AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQ 254
+ AQ + AQ + +Q A+ Q A+ Q A+ +Q
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 255 AVGASTPTTSSPAPAV-------STSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPS 307
G++ P P PA ST S P S + + + T
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 308 SAVSVATPTVSVSTPAPTA--TPVQTVPQPHPQTLPPAVPHSVPQPT--------TAIPA 357
S + PTVS S P + P P + L VP T ++
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 358 FPP-----------VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMA 406
F P + + L G P+P ++ + P T A +K+ P
Sbjct: 623 FNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT 682
Query: 407 PPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEK 466
P P+ ++ +P V + T + + K + KP KE
Sbjct: 683 SPKKDAA-PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA---KQPPEADSLSKPAPPKEP 738
Query: 467 EKLEEKIKEPIKEPSEEPLPMETEEED-------PKEEPIKEIKEEPKEEEMTEEEKAAQ 519
E+ K P+ + + M D + I K + + EE T
Sbjct: 739 SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD 798
Query: 520 KAKPVATAPIPG 531
AKP + P G
Sbjct: 799 SAKPSQSFPPTG 810
Score = 64.3 bits (155), Expect = 6e-10
Identities = 203/1057 (19%), Positives = 375/1057 (35%), Gaps = 149/1057 (14%)
Query: 33 APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92
AP P++ P P ++ P P+P P D P P P PP
Sbjct: 651 APVPSS----PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA--APKQDLSKAPEPKKPP 704
Query: 93 HLQRPPFM---PPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVEN-KTPDGKVY 148
L + P + P + PP + P P P P+ + + K P
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK--EPSVPSEQDKAPVADDKPKQPKMVKP 762
Query: 149 YYNARTRESAWTKPD--GVKVIQQSE--LTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQ 204
+ + SA TKPD KV Q+E TP L + +Q+ + + ++A
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT-GEKVSPFDSKAI 821
Query: 205 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTS 264
+ + ++ + ++++ Q Q + + +AQ + + + G+ TP
Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
Query: 265 SPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAP 324
P + T +P + + ++ P +Q TP V+ S +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 325 TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQ 384
+ + T QP PHS P P + P P P G
Sbjct: 942 ASNLISTAGQPG--------PHSQSGPG----------APMKQAPAPSQPPTSQG----- 978
Query: 385 IVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGK 444
P T G APP P +I T A A +E E K
Sbjct: 979 ----PPKST----------GQAPPA-----PAKSIPVKKETKAPA---AEKLEPKAEQAP 1016
Query: 445 TYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE 504
T RT T +KP +K+ + L EP + LP + E+ E K
Sbjct: 1017 TV---KRT--ETEKKPPPIKDSKSL-------TAEPQKAVLPTKLEKSPKPESTCPLCKT 1064
Query: 505 EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDE-RVFFYNPT---TRLSMWDRPD 560
E + + P C + +NPT T + W +
Sbjct: 1065 ELN----------------IGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLN 1108
Query: 561 DLIGRA---DVDKIIQEPPHKKGME--------ELKKLRHPTPTMLSIQKWQFSMSAIKE 609
RA + I + PP G + E + P + + K Q +
Sbjct: 1109 CQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEA 1168
Query: 610 EQELMEEINED------EPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARM 663
E+ ++E++ E P+ +K++++K ++ +K +A++ + E+ ++P E ++
Sbjct: 1169 EKVILEKVKETLSMEKIPPMVTTDQKQEESK-LEKDKASALQEKKPLPEEKKLIPEEEKI 1227
Query: 664 K-QFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEE--ERRE 720
+ + K LLE E K++ P P+E+K + AEE E R
Sbjct: 1228 RSEEKKPLLEEKKPT-----PEDKKLL--PEAKTSAPEEQKHDLLKSQVQIAEEKLEGRV 1280
Query: 721 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDR--EALFNEFVA 778
+ + K+ KM P++ E D K I++ A ++
Sbjct: 1281 APKTVQEGKQPQTKMEGLPSGTPQSLPKE------DDKTTKTIKEQPQPPCTAKPDQVEP 1334
Query: 779 AARKKEKEDSK---TRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSM 835
K EKED K + ++ KS + LS+ S S + + P + +
Sbjct: 1335 GKEKTEKEDDKSDTSSSQQPKSP--QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGL 1392
Query: 836 REDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHK 895
++D F Q + + ++ E + +AS E+ +K + + EQ K
Sbjct: 1393 KKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSP-----EQPK 1447
Query: 896 REEAIQNFKALLSDMVRSSDVSWSDTRR--TLRKDHRWESGSLLEREEKEKLFNEHIEAL 953
+E Q+ L + ++ S R T +KD + + S + +EK +E ++ +
Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEK----SEFVDDI 1503
Query: 954 TKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYI 1013
T ++ + ++E+S + + ++ ++ D + E E++IR + I
Sbjct: 1504 TTRREPY--DSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561
Query: 1014 TAKAD-FRTLLKETKFITYRSKKLIQESDQHLKDVEK 1049
AD + ++ +FI + K++ ++ K+ K
Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598
Score = 58.9 bits (141), Expect = 3e-08
Identities = 90/365 (24%), Positives = 114/365 (31%), Gaps = 70/365 (19%)
Query: 36 PNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPP----MPPPGGIPPPMGP 91
P +++ PP +PP P +GP P G P + P PPG P GP
Sbjct: 203 PEGIIK-PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGP 261
Query: 92 PH----------LQRPPFMPPPM--------SSMPPPPGMMFPPGMPPVTAPGTPALPPT 133
LQR P S P P P PP+ P TP PP
Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS----PSKPPIQQP-TPGKPPA 316
Query: 134 EEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ-AQVQAQAQAQAQ 192
++ E P KP Q S LT LA Q V+ Q
Sbjct: 317 QQPGHEKSQPGP--------------AKPPA----QPSGLTKPLAQQPGTVKPPVQPPGT 358
Query: 193 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQ 252
+ AQ A+ AQ Q ++ + Q +A AQ + Q A+
Sbjct: 359 TKPPAQPLGPAKPPAQ-------QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 253 AQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSV 312
Q VG P P +P+ T T P Q ++
Sbjct: 412 TQQVGTPKPLAQQP--------GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
Query: 313 ATPTVSVS-TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP 371
PT S P P P Q QP P PP P S P+ P PP + P P
Sbjct: 464 TGPTKPPSQLPGPAKPPPQ---QPGPAKPPPQQPGSAKPPSQQ----PGSTKPPPQQPGP 516
Query: 372 GMPIP 376
P P
Sbjct: 517 AKPSP 521
Score = 48.1 bits (113), Expect = 4e-05
Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 60 PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM 119
P PRP F D + P PPP PPP PP PP +PPP S P + P
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP----TILPKKK 2442
Query: 120 PPVTAPGTPALP 131
V +P T A P
Sbjct: 2443 LTVASPVTTATP 2454
Score = 42.7 bits (99), Expect = 0.002
Identities = 103/500 (20%), Positives = 159/500 (31%), Gaps = 64/500 (12%)
Query: 81 PPGGIPPPMGP-PHLQRPPFM----PPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEE 135
P G +PP P + R + PP S PP PG PG+ T+
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRT--------TDT 118
Query: 136 IWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQ----SELTPMLAAQAQVQAQAQAQA 191
E K P + + +S + K SE+ + A + V
Sbjct: 119 FRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 192 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQV 251
+ ++A + + Q Q + Q + + + Q Q Q Q + +Q
Sbjct: 179 ISDSEASQEETTKKQKVVQKE-QGKPEGIIKPPLQQQPPKPIPKQ---QGPGRDPLQQDG 234
Query: 252 QAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQ-------DQ 304
+++ + P P T P+ T T + + S P T+ +
Sbjct: 235 TPKSISSQQPEKIKSQPP-GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293
Query: 305 TPSSAVSVATPTVSVSTPA--PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAF--PP 360
S S + P + TP P P QP P PPA P + +P P PP
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 361 VMVPPFRVPLPGMPIPLPGVAMMQIVS------CPYVKTVA----TTKT-GVLPGMAPPI 409
V PP P P+ Q S P K +A KT PG A P
Sbjct: 353 VQ-PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 410 VPMIHPQVAIA-----ASPATLAGATAV-------SEWTEYKTADGKTYYYNNRTLESTW 457
+ +A SPA G T + + GKT +
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 458 EKPQELKEKEKLEEKIKEPIKEPSEEPLPME----TEEEDPKEEPIKEIKEEPKEEEMTE 513
+ P K + K P ++P P + T+ + P K ++P +
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 514 EEKAAQKAKPVATAPIPGTP 533
++ + AKP A P P P
Sbjct: 532 QQPGS--AKPSAQQPSPAKP 549
Score = 38.1 bits (87), Expect = 0.046
Identities = 23/63 (36%), Positives = 25/63 (39%), Gaps = 2/63 (3%)
Query: 72 FDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPM--SSMPPPPGMMFPPGMPPVTAPGTPA 129
F P P G P P RP F + S+ PPPP PP PP P P
Sbjct: 2367 FGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
Query: 130 LPP 132
LPP
Sbjct: 2427 LPP 2429
Score = 35.4 bits (80), Expect = 0.30
Identities = 87/462 (18%), Positives = 171/462 (37%), Gaps = 58/462 (12%)
Query: 454 ESTWEKPQELKEKEK-----LEEKIKEPIKEPSEEPL-PMETEEEDPKEEPIKEIKEEPK 507
ES+ P +L + E LE + E SE+ P E E PK++ + E
Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459
Query: 508 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 567
E ++EEE + + T + D + + + DD+ R +
Sbjct: 1460 EITISEEEIKESQEERKDT-----------FKKDSQQDIPSSKDHKEKSEFVDDITTRRE 1508
Query: 568 VDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW--QFSMSAIKEEQELMEEINEDEPVKA 625
++E + ++ R + S ++ + S + +EE + ++I E +
Sbjct: 1509 PYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADED 1568
Query: 626 KKRKRDDN------KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFS 679
DD K+I S E+ + E K + + R+ + ++
Sbjct: 1569 ASGSEDDEFIRNQLKEISSSTESQKKEETKG-KGKITAGKHRRLTRKSSTSIDEDAGRRH 1627
Query: 680 TWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEA 739
+W E + FD+ + + E + ++ +++ + +
Sbjct: 1628 SWHDE-----------------DDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTI 1670
Query: 740 KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDF 799
+ N S A K++ +S K D E E + ED ++RGE S
Sbjct: 1671 ELN-----STIADKYSAESSQKKTSLYFDEEP---ELEMESLTDSPED-RSRGEGSSS-- 1719
Query: 800 FELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKEL 859
S S + S + + +S P +K +S R+ + + + DS +E+EL
Sbjct: 1720 LHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEEL 1779
Query: 860 -ERQARIEASLREREREVQKARS---EQTKEIDREREQHKRE 897
E + ++ ++RE E Q+ +S + K+ D R Q +RE
Sbjct: 1780 REEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRE 1821
Score = 31.6 bits (70), Expect = 4.3
Identities = 38/154 (24%), Positives = 54/154 (35%), Gaps = 26/154 (16%)
Query: 273 STSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT-------------VSV 319
S+ + P +TT TS +T Q PS + SV++ +S
Sbjct: 2345 SSVIALPMKEQLSTTYFTS-GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISA 2403
Query: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPF--RVPLPGMPIPL 377
P P P P P P PP P + P+P T +P + P PL L
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP-TILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 378 PGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVP 411
A+++ P + T APP VP
Sbjct: 2463 ETTAVLRSNGLPVTRICTT---------APPPVP 2487
Score = 31.6 bits (70), Expect = 4.3
Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 20/110 (18%)
Query: 261 PTTSSPAPA--------VSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQT------P 306
P +SP P V++ +++TP TT T+V ++ P T+ T P
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 307 SSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIP 356
S+ + V P P+ P+ P+ + P +P + +PT P
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIA------PKPVIPQLPTTTQKPTDIHP 2531
Score = 31.6 bits (70), Expect = 4.3
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 214 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV-----------GASTPT 262
Q + + QAQ + + AQ Q Q + Q+Q Q+ Q++ Q + G ++P
Sbjct: 3270 QQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYNYDPSGTASPQ 3329
Query: 263 TSSPAPAVSTSTSSSTPS---STTSTTTTATSVAQTVSTPTTQ 302
T++ + ++ S +T TTTA++V + P +Q
Sbjct: 3330 TTTEQAILEGQYAALEGSQFWATEDATTTASAVV-AIEIPQSQ 3371
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,080,086
Number of Sequences: 37866
Number of extensions: 3764219
Number of successful extensions: 106600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1304
Number of HSP's successfully gapped in prelim test: 2433
Number of HSP's that attempted gapping in prelim test: 25609
Number of HSP's gapped (non-prelim): 34992
length of query: 1098
length of database: 18,247,518
effective HSP length: 113
effective length of query: 985
effective length of database: 13,968,660
effective search space: 13759130100
effective search space used: 13759130100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.