Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 21314774
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21314774 T-cell activation Rho GTPase-activating protein
isoform b [Homo sapiens]
(731 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21314774 T-cell activation Rho GTPase-activating protein isof... 1451 0.0
gi|23199971 T-cell activation Rho GTPase-activating protein isof... 1102 0.0
gi|20270373 T-cell activation Rho GTPase-activating protein isof... 515 e-146
gi|51479148 Rho GTPase activating protein 20 [Homo sapiens] 187 2e-47
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 106 9e-23
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 105 1e-22
gi|54860105 nadrin isoform 2 [Homo sapiens] 102 2e-21
gi|156119615 myosin IXA [Homo sapiens] 100 4e-21
gi|54860079 nadrin isoform 1 [Homo sapiens] 100 6e-21
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 91 4e-18
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 91 4e-18
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 91 4e-18
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 91 4e-18
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 89 2e-17
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 89 2e-17
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 84 5e-16
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 84 5e-16
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 84 5e-16
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 80 7e-15
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 80 9e-15
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 79 1e-14
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 79 1e-14
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a... 79 1e-14
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b... 78 3e-14
gi|188497642 ARHGAP15 [Homo sapiens] 77 4e-14
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 76 1e-13
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 76 1e-13
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 75 2e-13
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 75 3e-13
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 74 5e-13
>gi|21314774 T-cell activation Rho GTPase-activating protein isoform
b [Homo sapiens]
Length = 731
Score = 1451 bits (3756), Expect = 0.0
Identities = 731/731 (100%), Positives = 731/731 (100%)
Query: 1 MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSW 60
MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSW
Sbjct: 1 MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSW 60
Query: 61 PFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEG 120
PFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEG
Sbjct: 61 PFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEG 120
Query: 121 IFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMG 180
IFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMG
Sbjct: 121 IFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMG 180
Query: 181 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 240
ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN
Sbjct: 181 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 240
Query: 241 MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSD 300
MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSD
Sbjct: 241 MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSD 300
Query: 301 VSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVS 360
VSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVS
Sbjct: 301 VSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVS 360
Query: 361 TVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEAED 420
TVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEAED
Sbjct: 361 TVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEAED 420
Query: 421 PFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSP 480
PFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSP
Sbjct: 421 PFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSP 480
Query: 481 KRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDHVP 540
KRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDHVP
Sbjct: 481 KRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDHVP 540
Query: 541 RGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEEAM 600
RGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEEAM
Sbjct: 541 RGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEEAM 600
Query: 601 QGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGHGL 660
QGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGHGL
Sbjct: 601 QGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGHGL 660
Query: 661 SPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVFEA 720
SPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVFEA
Sbjct: 661 SPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVFEA 720
Query: 721 DQFQYAKESYI 731
DQFQYAKESYI
Sbjct: 721 DQFQYAKESYI 731
>gi|23199971 T-cell activation Rho GTPase-activating protein isoform
a [Homo sapiens]
Length = 553
Score = 1102 bits (2850), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 179 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 238
MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG
Sbjct: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
Query: 239 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 298
PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS
Sbjct: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 120
Query: 299 SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI 358
SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI
Sbjct: 121 SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI 180
Query: 359 VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA 418
VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA
Sbjct: 181 VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA 240
Query: 419 EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS 478
EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS
Sbjct: 241 EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS 300
Query: 479 SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH 538
SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH
Sbjct: 301 SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH 360
Query: 539 VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE 598
VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE
Sbjct: 361 VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE 420
Query: 599 AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH 658
AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH
Sbjct: 421 AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH 480
Query: 659 GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF 718
GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF
Sbjct: 481 GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF 540
Query: 719 EADQFQYAKESYI 731
EADQFQYAKESYI
Sbjct: 541 EADQFQYAKESYI 553
>gi|20270373 T-cell activation Rho GTPase-activating protein isoform
c [Homo sapiens]
Length = 266
Score = 515 bits (1326), Expect = e-146
Identities = 262/262 (100%), Positives = 262/262 (100%)
Query: 1 MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSW 60
MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSW
Sbjct: 1 MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSW 60
Query: 61 PFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEG 120
PFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEG
Sbjct: 61 PFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEG 120
Query: 121 IFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMG 180
IFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMG
Sbjct: 121 IFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMG 180
Query: 181 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 240
ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN
Sbjct: 181 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 240
Query: 241 MLTLENDQSLSFEAQKDLNNKV 262
MLTLENDQSLSFEAQKDLNNKV
Sbjct: 241 MLTLENDQSLSFEAQKDLNNKV 262
>gi|51479148 Rho GTPase activating protein 20 [Homo sapiens]
Length = 1191
Score = 187 bits (476), Expect = 2e-47
Identities = 108/299 (36%), Positives = 179/299 (59%), Gaps = 6/299 (2%)
Query: 23 ECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSWPFLMRRLSPASDFSGALETDLK 82
E Q + +K L A+ + DS + K+R+ +++W F + + + + +
Sbjct: 302 EMQCQFILKPSRLAAAQQLSDSGHKTF--KRRRSIINWAFWRGSSTHLDNLPSSPTSPMP 359
Query: 83 ASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGD 142
LF L IC ++D LP+P+ D+L L KGP T+GIFR++AN K+ +ELKE+LNSG
Sbjct: 360 GQLFGISLPNIC-ENDNLPKPVLDMLFFLNQKGPLTKGIFRQSANVKSCRELKEKLNSGV 418
Query: 143 AVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLP 202
V L+ + ++A V KDFLR+IP + SSDL++ W+ ++ ++E++I ++++ D+LP
Sbjct: 419 EVHLDCESIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGNDEEKINTVQRLLDQLP 478
Query: 203 RPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKV 262
R N++LL++L VLH I ++S N+M + NLA+C+ P++L S S E + + KV
Sbjct: 479 RANVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILW--PPASSSPELENEFTKKV 536
Query: 263 KTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSDVSTLQ-NDSAYDSNDPDVESN 320
L++FLI+NC IFGE I S ++SD+S Q NDS+YDS + ++ +
Sbjct: 537 SLLIQFLIENCLRIFGEEITSLFREVSVRCDTRENASDISCFQLNDSSYDSLENELNED 595
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 106 bits (264), Expect = 9e-23
Identities = 64/183 (34%), Positives = 108/183 (59%), Gaps = 7/183 (3%)
Query: 96 DSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLL 154
+ + +P +++ + L +TEGIFRR+AN + +E++++ N G VD ++ +HL
Sbjct: 255 EQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLP 314
Query: 155 AVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVY 214
AV+ K FLR +P LL+ DL+ +G L + DE R+ A QV LP N +L+ L
Sbjct: 315 AVILKTFLRELPEPLLTFDLYPHVVGFLNI-DESQRVPATLQVLQTLPEENYQVLRFLTA 373
Query: 215 VLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCF 274
L IS +S+ N+M ++NLA+ GPN+L + D +++ +A N + T +FL+D+
Sbjct: 374 FLVQISAHSDQNKMTNTNLAVVFGPNLLWAK-DAAITLKA----INPINTFTKFLLDHQG 428
Query: 275 EIF 277
E+F
Sbjct: 429 ELF 431
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 105 bits (263), Expect = 1e-22
Identities = 105/376 (27%), Positives = 170/376 (45%), Gaps = 33/376 (8%)
Query: 103 PIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL--PVHLLAVVFKD 160
PI+ + +L +G EG+FR AA K LK+ + S D LE H +A K
Sbjct: 292 PIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMAS-DPHSLEEFCSDPHAVAGALKS 350
Query: 161 FLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLIS 220
+LR +P L++ DL+++WM A +++ R++AL++V +LP NL L++L+ L ++
Sbjct: 351 YLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLA 410
Query: 221 KNSEVNRMDSSNLAICIGPNML---TLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIF 277
+ EVN+M SN+AI +GPN+L E DQ+ +A + +V +VE LI + +F
Sbjct: 411 EEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQA-QLDAASVSSIQVVGVVEALIQSADTLF 469
Query: 278 GENIPVH-SSITSDDSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPM 336
+I + S + S +L+ T S +++ S + + + +P+ P +
Sbjct: 470 PGDINFNVSGLFSAVTLQDTVSDRLAS----EELPSTAVPTPATTPAPAPAPAPAPAPAL 525
Query: 337 ATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQP----DRRY-----SEPSMPSSQ-E 386
A+AA + + EV P P V R A P RR + P+MP Q
Sbjct: 526 ASAATKE----RTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVS 581
Query: 387 CLESRVTNQTLTKSEGDFPVPR------VGSRLESEEAEDPF-PEEVFPAVQGKTKRPVD 439
S L G P+ VGS L + P P PA + + P
Sbjct: 582 GSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPAS 641
Query: 440 LKIKNLAPGSVLPRAL 455
+ P S P +L
Sbjct: 642 PSPASPGPASPSPVSL 657
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 102 bits (253), Expect = 2e-21
Identities = 80/310 (25%), Positives = 135/310 (43%), Gaps = 28/310 (9%)
Query: 103 PIQDILTILCLKGPSTEGIFRRAANEKARKELKEELN-SGDAVDLERLPVHLLAVVFKDF 161
PI+ + +L G EG+FR A K+LK L+ S +D H +A K +
Sbjct: 268 PIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSY 327
Query: 162 LRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISK 221
LR +P L++ +L+EEW +QD++ +++ L + KLP N + ++L+ L +++
Sbjct: 328 LRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQ 387
Query: 222 NSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENI 281
S+VN+M SN+AI +GPN+L N+ +L+ E + V ++E +I + F E +
Sbjct: 388 TSDVNKMTPSNIAIVLGPNLLWARNEGTLA-EMAAATSVHVVAVIEPIIQHADWFFPEEV 446
Query: 282 PV---------------HSSITSDDS----LEHTDSSDVSTLQNDSAYDSNDPDVESNSS 322
HS T +DS LE + ++ ++ D + P + S
Sbjct: 447 EFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVS 506
Query: 323 SGISSPSRQ-------PQVPMATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRR 375
+ + +P R P A A + Q P P A K + A P
Sbjct: 507 AAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPG 566
Query: 376 YSEPSMPSSQ 385
P P Q
Sbjct: 567 NPPPGHPGGQ 576
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 100 bits (250), Expect = 4e-21
Identities = 63/228 (27%), Positives = 126/228 (55%), Gaps = 11/228 (4%)
Query: 44 SICQLIEVKKRKKVLSWPFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRP 103
S+C+L + KK L + S + +L + F LS + + T+P
Sbjct: 2027 SVCKLCKYACHKKCC--------LKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLV 2078
Query: 104 IQDILTILCLKGPSTEGIFRRAANEKARKELKEELNS-GDAVDLERLPVHLLAVVFKDFL 162
++ ++ + + G TEGI+R++ + KEL++ L++ ++V+L+ +H++A VFK +L
Sbjct: 2079 VEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWL 2138
Query: 163 RSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKN 222
R +P L++ +L+EE++ A+ +Q+ ++ I + V D+L R +L L+ L++ L I+
Sbjct: 2139 RDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQ 2198
Query: 223 SEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLI 270
+ NRM ++ LAI P +L D + ++ +D+ +K T VE ++
Sbjct: 2199 EDTNRMSANALAIVFAPCILRCP-DTTDPLQSVQDI-SKTTTCVELIV 2244
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 100 bits (248), Expect = 6e-21
Identities = 104/421 (24%), Positives = 173/421 (41%), Gaps = 54/421 (12%)
Query: 103 PIQDILTILCLKGPSTEGIFRRAANEKARKELKEELN-SGDAVDLERLPVHLLAVVFKDF 161
PI+ + +L G EG+FR A K+LK L+ S +D H +A K +
Sbjct: 268 PIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSY 327
Query: 162 LRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISK 221
LR +P L++ +L+EEW +QD++ +++ L + KLP N + ++L+ L +++
Sbjct: 328 LRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQ 387
Query: 222 NSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENI 281
S+VN+M SN+AI +GPN+L N+ +L+ E + V ++E +I + F E +
Sbjct: 388 TSDVNKMTPSNIAIVLGPNLLWARNEGTLA-EMAAATSVHVVAVIEPIIQHADWFFPEEV 446
Query: 282 PV---------------HSSITSDDS----LEHTDSSDVSTLQND----SAYDSNDPDVE 318
HS T +DS LE + ++ ++ D ++ D +
Sbjct: 447 EFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQ 506
Query: 319 SNSSSGI-----SSPSRQPQVPMATAAGLDSAG----PQDAREVSPE---PIVSTVARLK 366
++ G SP+ QP +P + + AG PQ +R S + S+ L+
Sbjct: 507 AHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILE 566
Query: 367 SSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRL----ESEEAEDPF 422
+ D +P P S N + + P GS + A P
Sbjct: 567 QGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQ-PQAAAGSHQLSMGQPHNAAGPS 625
Query: 423 PEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSPKR 482
P + AV K P K N PG S +S P SP P R
Sbjct: 626 PHTLRRAV--KKPAPAPPKPGNPPPGHP----------GGQSSSGTSQHPPSLSPKPPTR 673
Query: 483 N 483
+
Sbjct: 674 S 674
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 90.9 bits (224), Expect = 4e-18
Identities = 55/172 (31%), Positives = 97/172 (56%), Gaps = 3/172 (1%)
Query: 98 DTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAV 156
+ +P ++ +T L KG TEG+FRR+A+ + +E++ N G V+ + +H+ AV
Sbjct: 329 ELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAV 388
Query: 157 VFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVL 216
+ K FLR +P+ LL+ +E+ +G + + R+ +Q+ LP N ++L++L+ L
Sbjct: 389 ILKTFLRELPQPLLTFQAYEQILG-ITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFL 447
Query: 217 HLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEF 268
H +S+ S N+M+SSNLA G N++ S S A LN + L+E+
Sbjct: 448 HAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS-SLSALVPLNMFTELLIEY 498
>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
sapiens]
Length = 433
Score = 90.9 bits (224), Expect = 4e-18
Identities = 55/172 (31%), Positives = 97/172 (56%), Gaps = 3/172 (1%)
Query: 98 DTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAV 156
+ +P ++ +T L KG TEG+FRR+A+ + +E++ N G V+ + +H+ AV
Sbjct: 207 ELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAV 266
Query: 157 VFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVL 216
+ K FLR +P+ LL+ +E+ +G + + R+ +Q+ LP N ++L++L+ L
Sbjct: 267 ILKTFLRELPQPLLTFQAYEQILG-ITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFL 325
Query: 217 HLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEF 268
H +S+ S N+M+SSNLA G N++ S S A LN + L+E+
Sbjct: 326 HAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS-SLSALVPLNMFTELLIEY 376
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 90.9 bits (224), Expect = 4e-18
Identities = 51/172 (29%), Positives = 102/172 (59%), Gaps = 4/172 (2%)
Query: 103 PIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERLPV--HLLAVVFKD 160
PI+ +T+L G EG+FR A + K+LK L+ VD++ H +A K
Sbjct: 271 PIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC-VVDVQEYSADPHAIAGALKS 329
Query: 161 FLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLIS 220
+LR +P L++ +L++EW+ A +Q+++ +++AL +KLP+ N +++L+ L +S
Sbjct: 330 YLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLS 389
Query: 221 KNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDN 272
+ +VN+M SN+AI +GPN+L + + +++ E ++ ++ ++E +I +
Sbjct: 390 EYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT-EMMTTVSLQIVGIIEPIIQH 440
>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
sapiens]
Length = 464
Score = 90.9 bits (224), Expect = 4e-18
Identities = 55/172 (31%), Positives = 97/172 (56%), Gaps = 3/172 (1%)
Query: 98 DTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAV 156
+ +P ++ +T L KG TEG+FRR+A+ + +E++ N G V+ + +H+ AV
Sbjct: 238 ELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAV 297
Query: 157 VFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVL 216
+ K FLR +P+ LL+ +E+ +G + + R+ +Q+ LP N ++L++L+ L
Sbjct: 298 ILKTFLRELPQPLLTFQAYEQILG-ITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFL 356
Query: 217 HLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEF 268
H +S+ S N+M+SSNLA G N++ S S A LN + L+E+
Sbjct: 357 HAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS-SLSALVPLNMFTELLIEY 407
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 88.6 bits (218), Expect = 2e-17
Identities = 135/533 (25%), Positives = 209/533 (39%), Gaps = 71/533 (13%)
Query: 100 LPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAVVF 158
+PR + L G T GIFR +++K ++L+EE + G V LE VH +A +
Sbjct: 207 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 266
Query: 159 KDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHL 218
K+FLR +P LL+ +L+ ++ L ++ EE ++ L+ + LP N L L+ L +
Sbjct: 267 KEFLRDMPDPLLTRELYTAFINTLLLEPEE-QLGTLQLLIYLLPPCNCDTLHRLLQFLSI 325
Query: 219 ISKNSE-----------VNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVE 267
++++++ N+M S NLA GPN+L + F Q + T +
Sbjct: 326 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAII 385
Query: 268 FLIDNCFEIFGENIPVHSSITSD--DSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGI 325
++ E + V + ++ SL TD V L A S+ PD+ S
Sbjct: 386 AVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDM-LQSEVSF 444
Query: 326 SSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQ 385
S R +T + S+G ++SP S V +S LA E + P
Sbjct: 445 SVGGRH----SSTDSNKASSG-----DISPYDNNSPVLSERSLLAM-----QEDAAPGGS 490
Query: 386 ECLESRVTNQTL-------TKSEGDFPVPRVGSRLESEEAEDPFPEEVFPAVQGKTKRPV 438
E L RV Q + +KS P PR+G L +E+PF +++
Sbjct: 491 EKL-YRVPGQFMLVGHLSSSKSRESSPGPRLGKDL----SEEPF--DIWGTWHS------ 537
Query: 439 DLKIKNLAPGSVLPRALVLKAFSSSSLDAS--SDSSPVASPSSPKRNFFSRHQSFTT--- 493
LK + PG + F SSSL A S S SP+ P+ T
Sbjct: 538 TLKSGSKDPGMTGSSGDI---FESSSLRAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGA 594
Query: 494 -KTEKGKPSREIKKHS--MSFTFAPHKKVLTKNLSAGSGKSQDFTRDHVPRGVRKESQLA 550
+T+ P+ E + H PH +V K + Q T E +A
Sbjct: 595 RRTQAAAPATEGRAHPAVSRACSTPHVQVAGKAERPTARSEQYLTLSGAHDLSESELDVA 654
Query: 551 GRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEEAMQGP 603
G A C RPH DD + PG P + +QGP
Sbjct: 655 GL----------QSRATPQCQRPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGP 697
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 88.6 bits (218), Expect = 2e-17
Identities = 135/533 (25%), Positives = 209/533 (39%), Gaps = 71/533 (13%)
Query: 100 LPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAVVF 158
+PR + L G T GIFR +++K ++L+EE + G V LE VH +A +
Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
Query: 159 KDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHL 218
K+FLR +P LL+ +L+ ++ L ++ EE ++ L+ + LP N L L+ L +
Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEE-QLGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
Query: 219 ISKNSE-----------VNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVE 267
++++++ N+M S NLA GPN+L + F Q + T +
Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAII 588
Query: 268 FLIDNCFEIFGENIPVHSSITSD--DSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGI 325
++ E + V + ++ SL TD V L A S+ PD+ S
Sbjct: 589 AVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDM-LQSEVSF 647
Query: 326 SSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQ 385
S R +T + S+G ++SP S V +S LA E + P
Sbjct: 648 SVGGRH----SSTDSNKASSG-----DISPYDNNSPVLSERSLLAM-----QEDAAPGGS 693
Query: 386 ECLESRVTNQTL-------TKSEGDFPVPRVGSRLESEEAEDPFPEEVFPAVQGKTKRPV 438
E L RV Q + +KS P PR+G L +E+PF +++
Sbjct: 694 EKL-YRVPGQFMLVGHLSSSKSRESSPGPRLGKDL----SEEPF--DIWGTWHS------ 740
Query: 439 DLKIKNLAPGSVLPRALVLKAFSSSSLDAS--SDSSPVASPSSPKRNFFSRHQSFTT--- 493
LK + PG + F SSSL A S S SP+ P+ T
Sbjct: 741 TLKSGSKDPGMTGSSGDI---FESSSLRAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGA 797
Query: 494 -KTEKGKPSREIKKHS--MSFTFAPHKKVLTKNLSAGSGKSQDFTRDHVPRGVRKESQLA 550
+T+ P+ E + H PH +V K + Q T E +A
Sbjct: 798 RRTQAAAPATEGRAHPAVSRACSTPHVQVAGKAERPTARSEQYLTLSGAHDLSESELDVA 857
Query: 551 GRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEEAMQGP 603
G A C RPH DD + PG P + +QGP
Sbjct: 858 GL----------QSRATPQCQRPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGP 900
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 84.0 bits (206), Expect = 5e-16
Identities = 64/257 (24%), Positives = 116/257 (45%), Gaps = 16/257 (6%)
Query: 82 KASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSG 141
+++ F PL+ + +P I+ + + G STEGI+R + N+ + L+ + +
Sbjct: 1243 ESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD 1302
Query: 142 DAVDLER--LPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVAD 199
+DL V+ +A K F +P L+ ++ + + A ++ D E ++ ALK+V
Sbjct: 1303 HNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLK 1362
Query: 200 KLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLN 259
K P+ N + K+++ L+ +S N++VN M S NL+IC P ++ + + A +
Sbjct: 1363 KFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATR--- 1419
Query: 260 NKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSDVSTLQNDSAYDSNDPDVES 319
+T++E I C F N P+ + S +S V L + P
Sbjct: 1420 -TYQTIIELFIQQC-PFFFYNRPITEPPGARPSSPSAVASTVPFLTSTPVTSQPSPP--- 1474
Query: 320 NSSSGISSPSRQPQVPM 336
SP PQ PM
Sbjct: 1475 ------QSPPPTPQSPM 1485
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 84.0 bits (206), Expect = 5e-16
Identities = 52/179 (29%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Query: 93 ICGDSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDA-VDLERLPV 151
+ D ++P ++ +L + + G TEG++R++ +EL++ L + A V LE P+
Sbjct: 1705 LTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPI 1764
Query: 152 HLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKH 211
H + V K +LR +P L++ + +++ A+E+ ++++++ A+ V + LP N L+
Sbjct: 1765 HAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLER 1824
Query: 212 LVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLI 270
L++ L ++ +VNRM LAI P +L D S + KD+ K+ T VE LI
Sbjct: 1825 LIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCP-DNSDPLTSMKDV-LKITTCVEMLI 1881
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 84.0 bits (206), Expect = 5e-16
Identities = 52/179 (29%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Query: 93 ICGDSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDA-VDLERLPV 151
+ D ++P ++ +L + + G TEG++R++ +EL++ L + A V LE P+
Sbjct: 1705 LTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPI 1764
Query: 152 HLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKH 211
H + V K +LR +P L++ + +++ A+E+ ++++++ A+ V + LP N L+
Sbjct: 1765 HAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLER 1824
Query: 212 LVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLI 270
L++ L ++ +VNRM LAI P +L D S + KD+ K+ T VE LI
Sbjct: 1825 LIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCP-DNSDPLTSMKDV-LKITTCVEMLI 1881
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 80.1 bits (196), Expect = 7e-15
Identities = 89/332 (26%), Positives = 144/332 (43%), Gaps = 38/332 (11%)
Query: 100 LPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAVVF 158
+PR + L G T GIFR +++K ++L+EE + G V LE VH +A +
Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
Query: 159 KDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHL 218
K+FLR +P LL+ +L+ ++ L ++ EE ++ L+ + LP N L L+ L +
Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEE-QLGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
Query: 219 ISKNSE-----------VNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVE 267
++++++ N+M S NLA GPN+L + F Q + T +
Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAII 588
Query: 268 FLIDNCFEIFGENIPVHSSITSD--DSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGI 325
++ E + V + ++ SL TD V L A S+ PD+ S
Sbjct: 589 AVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDM-LQSEVSF 647
Query: 326 SSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQ 385
S R +T + S+G ++SP S V +S LA E + P
Sbjct: 648 SVGGRH----SSTDSNKASSG-----DISPYDNNSPVLSERSLLAM-----QEDAAPGGS 693
Query: 386 ECLESRVTNQTL-------TKSEGDFPVPRVG 410
E L RV Q + +KS P PR+G
Sbjct: 694 EKL-YRVPGQFMLVGHLSSSKSRESSPGPRLG 724
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 79.7 bits (195), Expect = 9e-15
Identities = 69/278 (24%), Positives = 130/278 (46%), Gaps = 23/278 (8%)
Query: 114 KGPSTEGIFRRAANEKARKELKEELNSG----DAVDLERLPVHLLAVVFKDFLRSIPRKL 169
+G GI+R N A ++EELN G D D + +++++ + K F R +P L
Sbjct: 1175 RGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPL 1234
Query: 170 LSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMD 229
++D + +++ A +D DR++ LK++ LP + LK L L +++NSE N+M+
Sbjct: 1235 FTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKME 1294
Query: 230 SSNLAICIGPNML-TLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSIT 288
NLAI GP ++ T E++ + D V+TL++ D F G P+ +++
Sbjct: 1295 PRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQH-HDWFFTEEGAEEPL-TTVQ 1352
Query: 289 SDDSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQ 348
+ +++ ++ L + P S+S++ S+ S+ S Q
Sbjct: 1353 EESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATSDSTKSK---------GSWGSGKDQ 1403
Query: 349 DAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQE 386
+RE+ I + +R + ++ E + PSS E
Sbjct: 1404 YSRELLVSSIFAAASRKR-------KKPKEKAQPSSSE 1434
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
[Homo sapiens]
Length = 1099
Score = 79.3 bits (194), Expect = 1e-14
Identities = 51/210 (24%), Positives = 102/210 (48%), Gaps = 13/210 (6%)
Query: 61 PFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDS-DTLPRPIQDILTILCLKGPSTE 119
P MRR P S +S LF+ + DS +P ++ + + L G +
Sbjct: 487 PQKMRRPRPLSVYSH--------KLFNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQ 538
Query: 120 GIFRRAANEKARKELKEELNSGD---AVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFE 176
GIFR ++ ++K G+ D ++ +A V K + R + L + F+
Sbjct: 539 GIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQ 598
Query: 177 EWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAIC 236
+ + +++++ +R+ ++Q+ LPR ++++++L L+ +S+ S+ N MD NLAIC
Sbjct: 599 DLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAIC 658
Query: 237 IGPNMLTLENDQSLSFEAQKDLNNKVKTLV 266
GP ++ + + Q Q +N +KT++
Sbjct: 659 FGPTLMHIPDGQD-PVSCQAHINEVIKTII 687
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 79.0 bits (193), Expect = 1e-14
Identities = 58/223 (26%), Positives = 108/223 (48%), Gaps = 9/223 (4%)
Query: 100 LPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERLPVHLL---AV 156
+P ++ + + L G EGIFR + + E+++ G+ +E H L A
Sbjct: 520 VPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAG 579
Query: 157 VFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVL 216
V K + RS+ L DLF E + + E++ +R+E + ++ +LP P L++L++L L
Sbjct: 580 VLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFL 639
Query: 217 HLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEI 276
+ +++ S+ N MD NLA+C GP +L + Q L +V LV+ LI +
Sbjct: 640 NHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQD-----PVALQGRVNQLVQTLIVQPDRV 694
Query: 277 FGENIPVHSSITSDDSLEHTDSSDVSTLQNDSAYDSNDPDVES 319
F + + + + +S + Q +S N+P++E+
Sbjct: 695 FPPLTSLPGPV-YEKCMAPPSASCLGDAQLESLGADNEPELEA 736
>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
[Homo sapiens]
Length = 1071
Score = 79.0 bits (193), Expect = 1e-14
Identities = 104/446 (23%), Positives = 181/446 (40%), Gaps = 77/446 (17%)
Query: 97 SDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGD---AVDLERLPVHL 153
S +P ++ + + G EGIFR + ++ ++K G+ A D +
Sbjct: 501 SQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDS 560
Query: 154 LAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLV 213
+A V K + R + L D+F + M + M + ++R +++V LP+ L+++++L
Sbjct: 561 IAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLF 620
Query: 214 YVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLV---EFLI 270
L+ +S+ SE N MD NLAIC GP+++++ Q +N +KT++ E +
Sbjct: 621 AFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHD-QVSCQAHVNELIKTIIIQHENIF 679
Query: 271 DNCFEIFGENIPVHSSITS-----DDSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGI 325
+ E+ G PV+S S D T S + ST + + ++D + E
Sbjct: 680 PSPRELEG---PVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAEHHTSDDECE------- 729
Query: 326 SSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQ 385
P+ A D G + ARE+S + S + +R S+
Sbjct: 730 ---------PIEAIAKFDYVG-RTARELSFKKGASLLLY---------QRASDDWWEGRH 770
Query: 386 ECLESRVTNQ-TLTKSEGDFPVPRVGSRLESEEAEDPFPEEVFPAVQGKT----KRPVDL 440
++ + +Q + + D V R + E E +P PEE A G + D+
Sbjct: 771 NGIDGLIPHQYIVVQDTEDGVVERSSPKSEIEVISEP-PEEKVTARAGASCPSGGHVADI 829
Query: 441 KIKNLAPGSVLPRA-LVLKAF-------SSSSLDASS---------DSSPVASPSSPKR- 482
+ N+ P + + K F SSS D+SS S P+ S S PK
Sbjct: 830 YLANINKQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEG 889
Query: 483 ------------NFFSRHQSFTTKTE 496
N SRH S + +
Sbjct: 890 PDKCSISGHGSLNSISRHSSLKNRLD 915
>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
[Homo sapiens]
Length = 836
Score = 77.8 bits (190), Expect = 3e-14
Identities = 57/228 (25%), Positives = 101/228 (44%), Gaps = 26/228 (11%)
Query: 97 SDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGD---AVDLERLPVHL 153
S +P ++ + + G EGIFR + ++ ++K G+ A D +
Sbjct: 501 SQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDS 560
Query: 154 LAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLV 213
+A V K + R + L D+F + M + M + ++R +++V LP+ L+++++L
Sbjct: 561 IAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLF 620
Query: 214 YVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLV------- 266
L+ +S+ SE N MD NLAIC GP+++++ Q +N +KT++
Sbjct: 621 AFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHD-QVSCQAHVNELIKTIIIQHENIF 679
Query: 267 --------------EFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSD 300
+ D C GE V S T D + EH S D
Sbjct: 680 PSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDS-TQDVTAEHHTSDD 726
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 77.4 bits (189), Expect = 4e-14
Identities = 48/171 (28%), Positives = 87/171 (50%), Gaps = 4/171 (2%)
Query: 81 LKASLFDQPLSIICG-DSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELN 139
+K +F L +C ++ T+P ++ + + +G +GI+R + N ++L+ +N
Sbjct: 274 IKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN 333
Query: 140 SGDAVDLERLP---VHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQ 196
+ ++L+ +H++ K F R +P L FE+++ A++ QD RIEA+K
Sbjct: 334 QEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKS 393
Query: 197 VADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLEND 247
+ KLP PN +K L L I + N M + +L I GP +L EN+
Sbjct: 394 LVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENE 444
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 76.3 bits (186), Expect = 1e-13
Identities = 51/201 (25%), Positives = 101/201 (50%), Gaps = 8/201 (3%)
Query: 81 LKASLFDQPLSIICG-DSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELN 139
+K +F L+ +C + +PR +Q + + +G +G++R + N ++L+ +++
Sbjct: 322 IKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVD 381
Query: 140 SGDAVDLER---LPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQ 196
+ +DL+ VH++ K F R +P L F +++ A+++QD+ R ++
Sbjct: 382 HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRD 441
Query: 197 VADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQK 256
+ LP PN L+ L L + ++ E NRM ++AI GP +L E +++ S
Sbjct: 442 LVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEET-SMPMTM 500
Query: 257 DLNNKVKTLVEFLIDNCFEIF 277
N+V VE ++ C +IF
Sbjct: 501 VFQNQV---VELILQQCADIF 518
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 76.3 bits (186), Expect = 1e-13
Identities = 51/201 (25%), Positives = 101/201 (50%), Gaps = 8/201 (3%)
Query: 81 LKASLFDQPLSIICG-DSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELN 139
+K +F L+ +C + +PR +Q + + +G +G++R + N ++L+ +++
Sbjct: 349 IKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVD 408
Query: 140 SGDAVDLER---LPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQ 196
+ +DL+ VH++ K F R +P L F +++ A+++QD+ R ++
Sbjct: 409 HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRD 468
Query: 197 VADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQK 256
+ LP PN L+ L L + ++ E NRM ++AI GP +L E +++ S
Sbjct: 469 LVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEET-SMPMTM 527
Query: 257 DLNNKVKTLVEFLIDNCFEIF 277
N+V VE ++ C +IF
Sbjct: 528 VFQNQV---VELILQQCADIF 545
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
[Homo sapiens]
Length = 1075
Score = 75.5 bits (184), Expect = 2e-13
Identities = 40/170 (23%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Query: 100 LPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGD---AVDLERLPVHLLAV 156
+P ++ + + L G +GIFR ++ ++K G+ D ++ +A
Sbjct: 495 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 554
Query: 157 VFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVL 216
V K + R + L + F++ + +++++ +R+ ++Q+ LPR ++++++L L
Sbjct: 555 VLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFL 614
Query: 217 HLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLV 266
+ +S+ S+ N MD NLAIC GP ++ + + Q Q +N +KT++
Sbjct: 615 NHLSQYSDENMMDPYNLAICFGPTLMHIPDGQD-PVSCQAHINEVIKTII 663
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 74.7 bits (182), Expect = 3e-13
Identities = 66/288 (22%), Positives = 125/288 (43%), Gaps = 34/288 (11%)
Query: 73 FSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARK 132
F+G LET +K S +P ++ + + L G +GIFR + ++
Sbjct: 504 FNGDLETFVKDS------------GQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVN 551
Query: 133 ELKEELNSGD---AVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEED 189
++K G+ A D ++ +A V K + R + L + F + + + + + +
Sbjct: 552 DIKNSFERGENPLADDQSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYE 611
Query: 190 RIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQS 249
R ++++ LPR L+++++L L+ +S+ S+ N MD NLAIC GP ++ + Q
Sbjct: 612 RALHIRKLLLTLPRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQD 671
Query: 250 LSFEAQKDLNNKVKTLV---EFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSDVSTLQN 306
Q +N +KT++ E + + E+ G PV+ + D + S+ TL+
Sbjct: 672 -QVSCQAHVNEIIKTIIIHHETIFPDAKELDG---PVYEKCMAGDDYCDSPYSEHGTLEE 727
Query: 307 DSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVS 354
+P + P+ A D G + ARE+S
Sbjct: 728 VDQDAGTEPHTSEDECE-----------PIEAIAKFDYVG-RSARELS 763
>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
Length = 1528
Score = 73.9 bits (180), Expect = 5e-13
Identities = 74/296 (25%), Positives = 132/296 (44%), Gaps = 39/296 (13%)
Query: 4 RSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIE--VKKRKKVLSW- 60
+SSH S N++ I CQS + L S + L+E K SW
Sbjct: 1006 QSSHRPS----LNSVSLQINCQSVAQMN----LLQKYSLLKLTALLEKYTPSNKHGFSWA 1057
Query: 61 -PFLMRRLSPASDFSGALETDLKASLFDQPLSI-ICGDSDTLPRPIQDILTILCLKGPST 118
P M+R+ D+ S+F PL++ + LP+ IQ + L
Sbjct: 1058 VPKFMKRIK-VPDYKDR-------SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ 1109
Query: 119 EGIFRRAANEKARKELKEELNSG--DAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFE 176
G+FR++ K+R + ++N G D V+ E + +A + K + R +P L+++ L E
Sbjct: 1110 VGLFRKSG-VKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSE 1168
Query: 177 EWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAIC 236
++ + ++ R++A+K LP N +L+ L+Y L ++ + N+M +NLA+C
Sbjct: 1169 TFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVC 1228
Query: 237 IGPNML-------------TLENDQSLSFEAQKDLNNKVKTL--VEFLIDNCFEIF 277
+ P++ ++ QSL QKDLN + + +I C ++F
Sbjct: 1229 LAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLF 1284
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,982,822
Number of Sequences: 37866
Number of extensions: 1497900
Number of successful extensions: 5345
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 114
Number of HSP's that attempted gapping in prelim test: 4742
Number of HSP's gapped (non-prelim): 438
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.