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Search of human proteins with 21314755
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21314755 signal peptide peptidase-like 2A [Homo sapiens] 1048 0.0
gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo sa... 489 e-138
gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo sap... 489 e-138
gi|38524591 intramembrane protease 5 [Homo sapiens] 367 e-101
gi|33413418 signal peptide peptidase 3 [Homo sapiens] 106 6e-23
gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo ... 100 4e-21
gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo ... 100 4e-21
gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo ... 99 9e-21
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [... 36 0.075
gi|14150090 chromosome 2 open reading frame 7 [Homo sapiens] 33 0.82
gi|4503171 chemokine (C-X3-C motif) receptor 1 [Homo sapiens] 32 1.8
gi|4506163 presenilin 1 isoform I-467 [Homo sapiens] 31 3.1
gi|195947397 presenilin 1 isoform I-463 [Homo sapiens] 31 3.1
gi|238624132 large conductance calcium-activated potassium chann... 30 4.1
gi|238624130 large conductance calcium-activated potassium chann... 30 4.1
gi|62388890 large conductance calcium-activated potassium channe... 30 4.1
gi|26638650 large conductance calcium-activated potassium channe... 30 4.1
gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Ho... 30 4.1
gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Ho... 30 4.1
gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens] 30 4.1
gi|156104908 myosin heavy chain 6 [Homo sapiens] 30 5.3
gi|169210737 PREDICTED: hypothetical protein [Homo sapiens] 30 7.0
gi|156105681 presenilin 2 isoform 2 [Homo sapiens] 30 7.0
gi|156105679 presenilin 2 isoform 1 [Homo sapiens] 30 7.0
gi|219802232 solute carrier family 13, member 5 isoform b [Homo ... 29 9.1
gi|29171306 solute carrier family 13, member 5 isoform a [Homo s... 29 9.1
>gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
Length = 520
Score = 1048 bits (2709), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCMLYNPYWTALPSTLENAT 60
MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCMLYNPYWTALPSTLENAT
Sbjct: 1 MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCMLYNPYWTALPSTLENAT 60
Query: 61 SISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSVL 120
SISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSVL
Sbjct: 61 SISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSVL 120
Query: 121 FPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIAV 180
FPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIAV
Sbjct: 121 FPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIAV 180
Query: 181 FTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYFF 240
FTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYFF
Sbjct: 181 FTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYFF 240
Query: 241 YKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRGKNMEVRLIFLSGLCIAVA 300
YKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRGKNMEVRLIFLSGLCIAVA
Sbjct: 241 YKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRGKNMEVRLIFLSGLCIAVA 300
Query: 301 VVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPF 360
VVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPF
Sbjct: 301 VVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPF 360
Query: 361 ITKNGESIMVELAAGPFGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLI 420
ITKNGESIMVELAAGPFGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLI
Sbjct: 361 ITKNGESIMVELAAGPFGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLI 420
Query: 421 AYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVA 480
AYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVA
Sbjct: 421 AYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVA 480
Query: 481 WRRKEMKKFWKGNSYQMMDHLDCATNEENPVISGEQIVQQ 520
WRRKEMKKFWKGNSYQMMDHLDCATNEENPVISGEQIVQQ
Sbjct: 481 WRRKEMKKFWKGNSYQMMDHLDCATNEENPVISGEQIVQQ 520
>gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo
sapiens]
Length = 511
Score = 489 bits (1260), Expect = e-138
Identities = 239/503 (47%), Positives = 344/503 (68%), Gaps = 17/503 (3%)
Query: 7 LSPAGAALLWGFLLQLTAAQEA-------ILHASGNGTTKDYCMLYNPYWTALPSTLENA 59
++ A A LL FLL AAQ A ++ +G KDYC+LYNP W LP L A
Sbjct: 5 VAAALARLLAAFLL--LAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKA 62
Query: 60 TSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSV 119
+ + L N T++ LC+ +D+P G ++ +V G+C F EK R+AQ GA +L+V+
Sbjct: 63 SFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRER 122
Query: 120 LFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIA 179
L PP GN++++ ++ I +A +SYKD D+ G + +Y+P P DY MV+IF++A
Sbjct: 123 LVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMA 182
Query: 180 VFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYF 239
V TVA+GGYW+G +++ D K+++E + +P+ +FVV+CC M+VLLY+
Sbjct: 183 VGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYY 242
Query: 240 FYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRG-----KNMEVRLIFLSG 294
FY LVYV+I IFC+ASA LY+CLA + ++P+G+C I K + R++ L+
Sbjct: 243 FYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLLAL 302
Query: 295 LCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFF 354
C+AV+VVW VFRNED+WAW+LQD LGIAFCL ++KT++LP FK+C +LL +L LYD+FF
Sbjct: 303 FCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFF 362
Query: 355 VFITPFITKNGESIMVELAAGP--FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGD 412
VFITPF+TK+G SIMVE+A GP EKLP+V++VP+L S +++C P S+LGFGD
Sbjct: 363 VFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRL-NSSPLALCDRPFSLLGFGD 421
Query: 413 IIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCT 472
I+VPGLL+AYC RFD+Q SS +Y+V+ T+AY +G+++TFV L LM++GQPALLYLVPCT
Sbjct: 422 ILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCT 481
Query: 473 LITASVVAWRRKEMKKFWKGNSY 495
L+T+ VA R+E+ FW G+ +
Sbjct: 482 LVTSCAVALWRRELGVFWTGSGF 504
>gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo
sapiens]
Length = 592
Score = 489 bits (1260), Expect = e-138
Identities = 239/503 (47%), Positives = 344/503 (68%), Gaps = 17/503 (3%)
Query: 7 LSPAGAALLWGFLLQLTAAQEA-------ILHASGNGTTKDYCMLYNPYWTALPSTLENA 59
++ A A LL FLL AAQ A ++ +G KDYC+LYNP W LP L A
Sbjct: 5 VAAALARLLAAFLL--LAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKA 62
Query: 60 TSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSV 119
+ + L N T++ LC+ +D+P G ++ +V G+C F EK R+AQ GA +L+V+
Sbjct: 63 SFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRER 122
Query: 120 LFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIA 179
L PP GN++++ ++ I +A +SYKD D+ G + +Y+P P DY MV+IF++A
Sbjct: 123 LVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMA 182
Query: 180 VFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYF 239
V TVA+GGYW+G +++ D K+++E + +P+ +FVV+CC M+VLLY+
Sbjct: 183 VGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYY 242
Query: 240 FYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRG-----KNMEVRLIFLSG 294
FY LVYV+I IFC+ASA LY+CLA + ++P+G+C I K + R++ L+
Sbjct: 243 FYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLLAL 302
Query: 295 LCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFF 354
C+AV+VVW VFRNED+WAW+LQD LGIAFCL ++KT++LP FK+C +LL +L LYD+FF
Sbjct: 303 FCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFF 362
Query: 355 VFITPFITKNGESIMVELAAGP--FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGD 412
VFITPF+TK+G SIMVE+A GP EKLP+V++VP+L S +++C P S+LGFGD
Sbjct: 363 VFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRL-NSSPLALCDRPFSLLGFGD 421
Query: 413 IIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCT 472
I+VPGLL+AYC RFD+Q SS +Y+V+ T+AY +G+++TFV L LM++GQPALLYLVPCT
Sbjct: 422 ILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCT 481
Query: 473 LITASVVAWRRKEMKKFWKGNSY 495
L+T+ VA R+E+ FW G+ +
Sbjct: 482 LVTSCAVALWRRELGVFWTGSGF 504
>gi|38524591 intramembrane protease 5 [Homo sapiens]
Length = 684
Score = 367 bits (942), Expect = e-101
Identities = 208/537 (38%), Positives = 302/537 (56%), Gaps = 44/537 (8%)
Query: 11 GAALLWGFLLQLTAA---QEAILHASGNGTTKDYCMLYNPYWTALPSTLENATSISLMNL 67
G L GFLL ++ + + H +KDYC+L++ + LP L +A + L +
Sbjct: 5 GFLLPVGFLLLISTVAGGKYGVAHVVSENWSKDYCILFSSDYITLPRDLHHAPLLPLYDG 64
Query: 68 TSTPLCNLSDIPPVG---------IKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVN-- 116
T P C D P ++ +V G+C F K +AQ GA +L+V+
Sbjct: 65 TKAPWCPGEDSPHQAQLRSPSQRPLRQTTAMVMRGNCSFHTKGWLAQGQGAHGLLIVSRV 124
Query: 117 -----NSVLFPPSGNRSEFPDVKILIAFISYKDFRD-MNQTLGDNIT-VKMYSPSWPNFD 169
+ P R D+ I +A + Y D D ++ T G+ + V MY+P P D
Sbjct: 125 SDQQCSDTTLAPQDPRQPLADLTIPVAMLHYADMLDILSHTRGEAVVRVAMYAPPEPIID 184
Query: 170 YTMVVIFVIAVFTVALGGYWSGLVELENLK------------------AVTTEDREMRKK 211
Y M+VIF++AV TVA GGYW+GL E L+ A E +
Sbjct: 185 YNMLVIFILAVGTVAAGGYWAGLTEANRLQRRRARRGGGSGGHHQLQEAAAAEGAQKEDN 244
Query: 212 KEEYLTFSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKI 271
++ + F+P + V + C +M+LLYFFY VYV I IF + + + LY+CL+ L+ +
Sbjct: 245 EDIPVDFTPAMTGVVVTLSCSLMLLLYFFYDHFVYVTIGIFGLGAGIGLYSCLSPLVCHL 304
Query: 272 PYGQCTIACRG--KNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLI 329
Q ++ + L+ L+ LC V + W +RNEDRWAW+LQD LGI++CL ++
Sbjct: 305 SLRQYQRPPHSLWASLPLPLLLLASLCATVIIFWVAYRNEDRWAWLLQDTLGISYCLFVL 364
Query: 330 KTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPF--GNNEKLPVVI 387
++LP K+C L LL +DVFFVF+TPF TK GESIM ++A GP ++E+LP+V+
Sbjct: 365 HRVRLPTLKNCSSFLLALLAFDVFFVFVTPFFTKTGESIMAQVALGPAESSSHERLPMVL 424
Query: 388 RVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIG 447
+VP+L S +++C P SILGFGDI+VPG L+AYC RFDVQ S IY+V+ TVAYA+G
Sbjct: 425 KVPRL-RVSALTLCSQPFSILGFGDIVVPGFLVAYCCRFDVQVCSRQIYFVACTVAYAVG 483
Query: 448 MILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDHLDCA 504
+++TF+ +VLM+ GQPALLYLV TL+T+ VA R+E+ FW G M L CA
Sbjct: 484 LLVTFMAMVLMQMGQPALLYLVSSTLLTSLAVAACRQELSLFWTGQGRAKMCGLGCA 540
>gi|33413418 signal peptide peptidase 3 [Homo sapiens]
Length = 384
Score = 106 bits (264), Expect = 6e-23
Identities = 89/374 (23%), Positives = 169/374 (45%), Gaps = 55/374 (14%)
Query: 161 YSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLVELENLKAVTTEDREM-----RKKKEEY 215
YS ++ D + V F+I++ + G + S ++ EN +
Sbjct: 6 YSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSI 65
Query: 216 LTFSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKI---- 271
T + + V +++++FF+ + V + + ++ L + +
Sbjct: 66 QTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPC 125
Query: 272 -PYGQCTIACRGKNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIK 330
P + + C G+ L+ S L + + ++W + + W+L D L + C+ +I
Sbjct: 126 SPQNKISFGCCGRFTAAELLSFS-LSVMLVLIWVLTGH-----WLLMDALAMGLCVAMIA 179
Query: 331 TLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGN-----NEKL-- 383
++LP+ K +LL LL+YDVF+VF + +I + ++MV++A P N + KL
Sbjct: 180 FVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNS--NVMVKVATQPADNPLDVLSRKLHL 237
Query: 384 -PVVIR-VPKLIYFSVMSVCLMP------VSILGFGDIIVPGLLIAYCRRFD----VQTG 431
P V R VP+L S+ + P S+LG GDI++PGLL+ + R+D +G
Sbjct: 238 GPNVGRDVPRL---SLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASG 294
Query: 432 SS---------------YIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITA 476
S Y+ + + Y +G++ V + + QPALLYLVP TL+
Sbjct: 295 DSCGAPGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPL 354
Query: 477 SVVAWRRKEMKKFW 490
+A+ + ++++ W
Sbjct: 355 LTMAYLKGDLRRMW 368
>gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo
sapiens]
Length = 426
Score = 100 bits (248), Expect = 4e-21
Identities = 86/313 (27%), Positives = 148/313 (47%), Gaps = 47/313 (15%)
Query: 226 FVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKI-PYGQCTIACRGKN 284
F +I ++ LY F+K ++ I + S + AL H I P+ N
Sbjct: 78 FPIIASCTLLGLYLFFK--IFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPN 135
Query: 285 MEVRLIFLSG------------------LCI---AVAVVWAVFRNEDRWAWILQDILGIA 323
+ +L+F G +C+ ++ VW + R WI ++ G+A
Sbjct: 136 RQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKH----WIANNLFGLA 191
Query: 324 FCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKL 383
F LN ++ L L N + ILLG L +YDVF+VF G ++MV +A + +
Sbjct: 192 FSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GTNVMVTVA-----KSFEA 238
Query: 384 PVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQ-TGSSYIYYVSSTV 442
P+ + P+ + + ++LG GD+++PG+ IA RFD+ +++ Y+ +S
Sbjct: 239 PIKLVFPQDLLEKGLEA--NNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFA 296
Query: 443 AYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEM-KKFWKGNSYQMMDHL 501
AY G+ LT ++ + K QPALLYLVP + +VA + E+ + F +S +++ H
Sbjct: 297 AYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHT 356
Query: 502 DCATNEENPVISG 514
T+ P +SG
Sbjct: 357 PRLTH--FPTVSG 367
>gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo
sapiens]
Length = 394
Score = 100 bits (248), Expect = 4e-21
Identities = 86/313 (27%), Positives = 148/313 (47%), Gaps = 47/313 (15%)
Query: 226 FVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKI-PYGQCTIACRGKN 284
F +I ++ LY F+K ++ I + S + AL H I P+ N
Sbjct: 78 FPIIASCTLLGLYLFFK--IFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPN 135
Query: 285 MEVRLIFLSG------------------LCI---AVAVVWAVFRNEDRWAWILQDILGIA 323
+ +L+F G +C+ ++ VW + R WI ++ G+A
Sbjct: 136 RQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKH----WIANNLFGLA 191
Query: 324 FCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKL 383
F LN ++ L L N + ILLG L +YDVF+VF G ++MV +A + +
Sbjct: 192 FSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GTNVMVTVA-----KSFEA 238
Query: 384 PVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQ-TGSSYIYYVSSTV 442
P+ + P+ + + ++LG GD+++PG+ IA RFD+ +++ Y+ +S
Sbjct: 239 PIKLVFPQDLLEKGLEA--NNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFA 296
Query: 443 AYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEM-KKFWKGNSYQMMDHL 501
AY G+ LT ++ + K QPALLYLVP + +VA + E+ + F +S +++ H
Sbjct: 297 AYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHT 356
Query: 502 DCATNEENPVISG 514
T+ P +SG
Sbjct: 357 PRLTH--FPTVSG 367
>gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo
sapiens]
Length = 377
Score = 99.0 bits (245), Expect = 9e-21
Identities = 84/307 (27%), Positives = 144/307 (46%), Gaps = 47/307 (15%)
Query: 226 FVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKI-PYGQCTIACRGKN 284
F +I ++ LY F+K ++ I + S + AL H I P+ N
Sbjct: 78 FPIIASCTLLGLYLFFK--IFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPN 135
Query: 285 MEVRLIFLSG------------------LCI---AVAVVWAVFRNEDRWAWILQDILGIA 323
+ +L+F G +C+ ++ VW + R WI ++ G+A
Sbjct: 136 RQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKH----WIANNLFGLA 191
Query: 324 FCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKL 383
F LN ++ L L N + ILLG L +YDVF+VF G ++MV +A + +
Sbjct: 192 FSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GTNVMVTVA-----KSFEA 238
Query: 384 PVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQ-TGSSYIYYVSSTV 442
P+ + P+ + + ++LG GD+++PG+ IA RFD+ +++ Y+ +S
Sbjct: 239 PIKLVFPQDLLEKGLEA--NNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFA 296
Query: 443 AYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDHLD 502
AY G+ LT ++ + K QPALLYLVP + +VA + E+ + + SY+ + D
Sbjct: 297 AYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMF---SYEESNPKD 353
Query: 503 CATNEEN 509
A E+
Sbjct: 354 PAAVTES 360
>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
[Homo sapiens]
Length = 932
Score = 36.2 bits (82), Expect = 0.075
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 8/73 (10%)
Query: 80 PVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNN--------SVLFPPSGNRSEFP 131
P + K ++ G C F EKAR Q GA +V+++ + LF +G+ +
Sbjct: 699 PEAVMGKIALIQRGQCMFAEKARNIQNAGAIGGIVIDDNEGSSSDTAPLFQMAGDGKDTD 758
Query: 132 DVKILIAFISYKD 144
D+KI + F+ K+
Sbjct: 759 DIKIPMLFLFSKE 771
>gi|14150090 chromosome 2 open reading frame 7 [Homo sapiens]
Length = 188
Score = 32.7 bits (73), Expect = 0.82
Identities = 13/37 (35%), Positives = 23/37 (62%)
Query: 83 IKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSV 119
I+ + +V G C FL K R+ Q+ G A+++ +N+V
Sbjct: 83 IQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAV 119
>gi|4503171 chemokine (C-X3-C motif) receptor 1 [Homo sapiens]
Length = 355
Score = 31.6 bits (70), Expect = 1.8
Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
Query: 302 VWAVFRN-EDRWAWILQDILGIAFC-LNLIKTL-KLPNFKSCVILLGLLLLYDVFFVFIT 358
+W V RN E + L +L +++C +I+TL N K + +LL+ VFF+F T
Sbjct: 186 IWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWT 245
Query: 359 PF 360
P+
Sbjct: 246 PY 247
>gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]
Length = 467
Score = 30.8 bits (68), Expect = 3.1
Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 408 LGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPAL 465
LG GD I +L+ + + ++ VA IG+ LT ++L + KK PAL
Sbjct: 381 LGLGDFIFYSVLVG---KASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL 435
>gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]
Length = 463
Score = 30.8 bits (68), Expect = 3.1
Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 408 LGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPAL 465
LG GD I +L+ + + ++ VA IG+ LT ++L + KK PAL
Sbjct: 377 LGLGDFIFYSVLVG---KASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL 431
>gi|238624132 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform d [Homo sapiens]
Length = 1219
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 14/99 (14%)
Query: 320 LGIAF--CLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGP- 376
LG+ F L LI+ ++ F + + + L ++ +FI+ ++T G +VE + P
Sbjct: 269 LGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPW 328
Query: 377 --FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDI 413
F NN+ L Y+ + + ++ +S +G+GD+
Sbjct: 329 ENFQNNQ---------ALTYWECVYLLMVTMSTVGYGDV 358
>gi|238624130 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform c [Homo sapiens]
Length = 1236
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 14/99 (14%)
Query: 320 LGIAF--CLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGP- 376
LG+ F L LI+ ++ F + + + L ++ +FI+ ++T G +VE + P
Sbjct: 269 LGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPW 328
Query: 377 --FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDI 413
F NN+ L Y+ + + ++ +S +G+GD+
Sbjct: 329 ENFQNNQ---------ALTYWECVYLLMVTMSTVGYGDV 358
>gi|62388890 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform a [Homo sapiens]
Length = 1182
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 14/99 (14%)
Query: 320 LGIAF--CLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGP- 376
LG+ F L LI+ ++ F + + + L ++ +FI+ ++T G +VE + P
Sbjct: 269 LGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPW 328
Query: 377 --FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDI 413
F NN+ L Y+ + + ++ +S +G+GD+
Sbjct: 329 ENFQNNQ---------ALTYWECVYLLMVTMSTVGYGDV 358
>gi|26638650 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform b [Homo sapiens]
Length = 1178
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 14/99 (14%)
Query: 320 LGIAF--CLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGP- 376
LG+ F L LI+ ++ F + + + L ++ +FI+ ++T G +VE + P
Sbjct: 269 LGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPW 328
Query: 377 --FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDI 413
F NN+ L Y+ + + ++ +S +G+GD+
Sbjct: 329 ENFQNNQ---------ALTYWECVYLLMVTMSTVGYGDV 358
>gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Homo
sapiens]
Length = 492
Score = 30.4 bits (67), Expect = 4.1
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 12/88 (13%)
Query: 295 LCIAVAVVWAVFR----NEDRWAWILQDILGIA-FCLNLIKTLKLPNFKSCVILLGLLLL 349
L ++V +WA+ N D +W+L+ L + F L + L +K+ V L LL
Sbjct: 166 LMLSVITMWAIGYILDFNSD--SWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLL 223
Query: 350 YDVFFVFITPFITKNGESIMVELAAGPF 377
VF++F+T FI +LA PF
Sbjct: 224 SSVFWIFMTWFIL-----FFPDLAGAPF 246
>gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Homo
sapiens]
Length = 622
Score = 30.4 bits (67), Expect = 4.1
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 12/88 (13%)
Query: 295 LCIAVAVVWAVFR----NEDRWAWILQDILGIA-FCLNLIKTLKLPNFKSCVILLGLLLL 349
L ++V +WA+ N D +W+L+ L + F L + L +K+ V L LL
Sbjct: 296 LMLSVITMWAIGYILDFNSD--SWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLL 353
Query: 350 YDVFFVFITPFITKNGESIMVELAAGPF 377
VF++F+T FI +LA PF
Sbjct: 354 SSVFWIFMTWFIL-----FFPDLAGAPF 376
>gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]
Length = 305
Score = 30.4 bits (67), Expect = 4.1
Identities = 20/103 (19%), Positives = 42/103 (40%), Gaps = 15/103 (14%)
Query: 170 YTMVVIFVIAVFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVI 229
Y + ++F + +V W + L V T E R ++ LT+ P+ + + +
Sbjct: 15 YALNLLFWLMSISVLAVSAWMR----DYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAV 70
Query: 230 CCVMMVLLYFFY-----------KWLVYVMIAIFCIASAMSLY 261
CC ++++ Y W ++ IFC+ A ++
Sbjct: 71 CCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVW 113
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 30.0 bits (66), Expect = 5.3
Identities = 15/64 (23%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 192 LVELENLKAVTT-EDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIA 250
+ E EN K VT ED+ +++ ++ + ++ F+ V+ L + W++Y
Sbjct: 60 IAETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSG 119
Query: 251 IFCI 254
+FC+
Sbjct: 120 LFCV 123
>gi|169210737 PREDICTED: hypothetical protein [Homo sapiens]
Length = 219
Score = 29.6 bits (65), Expect = 7.0
Identities = 14/54 (25%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 223 VVIFVVICCVMMVLLYFFYKWLVYVMIAIF---CIASAMSLYNCLAALIHKIPY 273
+ ++V IC + +Y + VY+ I I+ C+ + +Y C+ IH Y
Sbjct: 162 ICVYVYICVYTYMCIYVYIHICVYMCIYIYVYICVYMCIYIYVCVYIYIHTHTY 215
>gi|156105681 presenilin 2 isoform 2 [Homo sapiens]
Length = 447
Score = 29.6 bits (65), Expect = 7.0
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 408 LGFGDIIVPGLLIAYCRRFDVQTGSS-YIYYVSSTVAYAIGMILTFVVLVLMKKGQPAL 465
LG GD I +L+ TGS + ++ VA IG+ LT ++L + KK PAL
Sbjct: 361 LGLGDFIFYSVLVGKA----AATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPAL 415
>gi|156105679 presenilin 2 isoform 1 [Homo sapiens]
Length = 448
Score = 29.6 bits (65), Expect = 7.0
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 408 LGFGDIIVPGLLIAYCRRFDVQTGSS-YIYYVSSTVAYAIGMILTFVVLVLMKKGQPAL 465
LG GD I +L+ TGS + ++ VA IG+ LT ++L + KK PAL
Sbjct: 362 LGLGDFIFYSVLVGKA----AATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPAL 416
>gi|219802232 solute carrier family 13, member 5 isoform b [Homo
sapiens]
Length = 522
Score = 29.3 bits (64), Expect = 9.1
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 21/111 (18%)
Query: 130 FPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYW 189
FPD K L+ F S+ F N + + +++ W F +++ F + G
Sbjct: 241 FPDSKDLVNFASWFAFAFPNM-----LVMLLFAWLWLQF------VYMRFNFKKSWG--- 286
Query: 190 SGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVV-IFVVICCVMMVLLYF 239
GL +N KA ++ +EEY PL+ I V+IC ++V+L+F
Sbjct: 287 CGLESKKNEKAA------LKVLQEEYRKLGPLSFAEINVLICFFLLVILWF 331
>gi|29171306 solute carrier family 13, member 5 isoform a [Homo
sapiens]
Length = 568
Score = 29.3 bits (64), Expect = 9.1
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 21/111 (18%)
Query: 130 FPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYW 189
FPD K L+ F S+ F N + + +++ W F +++ F + G
Sbjct: 241 FPDSKDLVNFASWFAFAFPNM-----LVMLLFAWLWLQF------VYMRFNFKKSWG--- 286
Query: 190 SGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVV-IFVVICCVMMVLLYF 239
GL +N KA ++ +EEY PL+ I V+IC ++V+L+F
Sbjct: 287 CGLESKKNEKAA------LKVLQEEYRKLGPLSFAEINVLICFFLLVILWF 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.140 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,674,494
Number of Sequences: 37866
Number of extensions: 765867
Number of successful extensions: 2409
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2362
Number of HSP's gapped (non-prelim): 46
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.