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Search of human proteins with 21264558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21264558 stromal membrane-associated GTPase-activating
protein 1 isoform B [Homo sapiens]
(440 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21264558 stromal membrane-associated GTPase-activating protei... 892 0.0
gi|113204622 stromal membrane-associated GTPase-activating prote... 877 0.0
gi|23943872 small ArfGAP2 [Homo sapiens] 368 e-102
gi|187608516 centaurin, beta 2 [Homo sapiens] 110 3e-24
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 102 7e-22
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 102 7e-22
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 100 3e-21
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 99 6e-21
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 99 8e-21
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 99 8e-21
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 99 1e-20
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 98 1e-20
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 98 2e-20
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 97 2e-20
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 97 4e-20
gi|6806913 centaurin, alpha 1 [Homo sapiens] 96 6e-20
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 94 2e-19
gi|8923763 centaurin-alpha 2 protein [Homo sapiens] 94 2e-19
gi|7661880 centaurin beta1 [Homo sapiens] 93 4e-19
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 90 4e-18
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 90 4e-18
gi|31543983 ADP-ribosylation factor GTPase activating protein 2 ... 87 4e-17
gi|46094081 development and differentiation enhancing factor 1 [... 86 7e-17
gi|214829714 ADP-ribosylation factor GTPase activating protein 3... 81 2e-15
gi|214829673 ADP-ribosylation factor GTPase activating protein 3... 80 4e-15
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 79 6e-15
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 79 6e-15
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 77 2e-14
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 77 2e-14
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 77 3e-14
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 892 bits (2305), Expect = 0.0
Identities = 440/440 (100%), Positives = 440/440 (100%)
Query: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH
Sbjct: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
Query: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR
Sbjct: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
Query: 121 DKYEKKKYYDKNAIAITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTS 180
DKYEKKKYYDKNAIAITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTS
Sbjct: 121 DKYEKKKYYDKNAIAITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTS 180
Query: 181 PKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPS 240
PKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPS
Sbjct: 181 PKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPS 240
Query: 241 APAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPT 300
APAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPT
Sbjct: 241 APAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPT 300
Query: 301 NIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPL 360
NIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPL
Sbjct: 301 NIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPL 360
Query: 361 PQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSS 420
PQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSS
Sbjct: 361 PQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSS 420
Query: 421 TTAGWSGSSSGQTLSTQLWK 440
TTAGWSGSSSGQTLSTQLWK
Sbjct: 421 TTAGWSGSSSGQTLSTQLWK 440
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 877 bits (2267), Expect = 0.0
Identities = 440/467 (94%), Positives = 440/467 (94%), Gaps = 27/467 (5%)
Query: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH
Sbjct: 1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 60
Query: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR
Sbjct: 61 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 120
Query: 121 DKYEKKKYYDKNAIAITN---------------------------KEKEKKKEEKKREKE 153
DKYEKKKYYDKNAIAITN KEKEKKKEEKKREKE
Sbjct: 121 DKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKE 180
Query: 154 PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN 213
PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN
Sbjct: 181 PEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLN 240
Query: 214 DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL 273
DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL
Sbjct: 241 DDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQL 300
Query: 274 SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM 333
SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM
Sbjct: 301 SKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVM 360
Query: 334 GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS 393
GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS
Sbjct: 361 GQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWS 420
Query: 394 LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 440
LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK
Sbjct: 421 LSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 467
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 368 bits (944), Expect = e-102
Identities = 215/444 (48%), Positives = 278/444 (62%), Gaps = 30/444 (6%)
Query: 9 KAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHIS 68
K+ K +++Q +L+ LL EEDNK+CADC++KGPRWASWNIGVFICIRCAGIHRNLGVHIS
Sbjct: 4 KSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHIS 63
Query: 69 RVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKY 128
RVKSVNLDQWT EQIQCMQ+MGN KA LYEA LPE FRRPQ D AVE FIRDKYEKKKY
Sbjct: 64 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY 123
Query: 129 YDKNAIAITNKEKEKKKEEKKREKEPEKPAKPLTAEKL---QKKDQQLEPKKSTSPKKAA 185
D++ ++++ K ++ E PEK +P+ EK+ QKK+ P+KS SPK A
Sbjct: 124 MDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKS-SPKSTA 182
Query: 186 EPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAA 245
P +DLLGLD P + N T+ L DLD+ + S P P++ + S P A
Sbjct: 183 -PVMDLLGLDAPVACSIANSKTS-NTLEKDLDL---LASVPSPSS-SGSRKVVGSMPTAG 236
Query: 246 TLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT 305
+ +V +L+LF E +KSEE+ KKQLSKDSILSLYG+ T Q T +FM P + +
Sbjct: 237 SAGSVPE-NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQT-PQMPTQAMFMAPAQMAY- 293
Query: 306 SQAPAAFQGFPS-------MGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVM 358
P A+ FP MG +P G++ + M+ M MP G+MG Q +M
Sbjct: 294 ---PTAYPSFPGVTPPNSIMGSMMPPPVGMV--AQPGASGMVAPMAMPAGYMGGMQASMM 348
Query: 359 PLPQNVVGPQ--GGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFG 416
+P ++ Q G M G PQ+ +G+ AQQ QW+L+QM QQMAGM+ A +G
Sbjct: 349 GVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYG 408
Query: 417 QPSSTTAGWSGSSSGQTLSTQLWK 440
Q S G +G ++ QTLS Q+WK
Sbjct: 409 QSMS---GGNGQAANQTLSPQMWK 429
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 110 bits (275), Expect = 3e-24
Identities = 53/127 (41%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Query: 30 NKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDM 89
N C DC PRWAS N+G+ +CI C+GIHR+LGVH S+V+S+ LD W E ++ M ++
Sbjct: 411 NASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCEL 470
Query: 90 GNTKARLLYEANLPE-NFRRPQTD--QAVEFFIRDKYEKKKYYDKNAIAITNKEKEKKKE 146
GN +YEAN+ + ++PQ Q E +IR KY ++K+ DK +I+++ E++KK
Sbjct: 471 GNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFV 530
Query: 147 EKKREKE 153
K E++
Sbjct: 531 SKSSEEK 537
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 102 bits (254), Expect = 7e-22
Identities = 48/127 (37%), Positives = 75/127 (59%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K++ ++ + L + N +C DCE + P WAS N+G +CI C+GIHRNLG
Sbjct: 543 SSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLG 602
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTD---QAVEFFIRD 121
H+SRV+S++LD W E I+ M +GN A ++E + + +P D + E +IR
Sbjct: 603 THLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEES-SQGRTKPSVDSTREEKERWIRA 661
Query: 122 KYEKKKY 128
KYE+K +
Sbjct: 662 KYEQKLF 668
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 102 bits (254), Expect = 7e-22
Identities = 48/127 (37%), Positives = 75/127 (59%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K++ ++ + L + N +C DCE + P WAS N+G +CI C+GIHRNLG
Sbjct: 596 SSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLG 655
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTD---QAVEFFIRD 121
H+SRV+S++LD W E I+ M +GN A ++E + + +P D + E +IR
Sbjct: 656 THLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEES-SQGRTKPSVDSTREEKERWIRA 714
Query: 122 KYEKKKY 128
KYE+K +
Sbjct: 715 KYEQKLF 721
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 100 bits (248), Expect = 3e-21
Identities = 50/128 (39%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 4 RSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNL 63
RS ++K + N+ L + + N +C DC+A P WAS N+G +CI C+GIHR+L
Sbjct: 648 RSAKDKTRLGNQNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHL 707
Query: 64 GVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTD---QAVEFFIR 120
G H+SRV+S++LD W E + M MGN A ++E L + +P D + E +IR
Sbjct: 708 GAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGAL-GGYSKPGPDACREEKERWIR 766
Query: 121 DKYEKKKY 128
KYE+K +
Sbjct: 767 AKYEQKLF 774
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 99.4 bits (246), Expect = 6e-21
Identities = 54/152 (35%), Positives = 83/152 (54%), Gaps = 5/152 (3%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
+L ++ N C DC PRWAS N+GV +CI C+GIHR+LGVH S+V+S+ LD W
Sbjct: 405 VLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWE 464
Query: 80 AEQIQCMQDMGNTKARLLYEANLP-ENFRRP---QTDQAVEFFIRDKYEKKKYYDKNAIA 135
E ++ M ++GN+ +YEA R+P + Q E +I+DKY +KK+ K +A
Sbjct: 465 PELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKAPMA 524
Query: 136 ITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQ 167
E ++ +K + P P K++
Sbjct: 525 -PALEAPRRWRVQKCLRPHSSPRAPTARRKVR 555
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 99.0 bits (245), Expect = 8e-21
Identities = 46/128 (35%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 4 RSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNL 63
+S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+
Sbjct: 450 KSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
Query: 64 GVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIR 120
G +SRV+S+ LD W E + M +GN A ++E + + +P T + E++IR
Sbjct: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGS-SQGQTKPSIKSTREEKEWWIR 568
Query: 121 DKYEKKKY 128
KYE+K +
Sbjct: 569 SKYEEKLF 576
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 99.0 bits (245), Expect = 8e-21
Identities = 46/128 (35%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 4 RSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNL 63
+S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+
Sbjct: 450 KSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
Query: 64 GVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIR 120
G +SRV+S+ LD W E + M +GN A ++E + + +P T + E++IR
Sbjct: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGS-SQGQTKPSIKSTREEKEWWIR 568
Query: 121 DKYEKKKY 128
KYE+K +
Sbjct: 569 SKYEEKLF 576
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 98.6 bits (244), Expect = 1e-20
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 428 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 487
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
+SRV+S+ LD W E + M +GN A ++E + + T + E +IR K
Sbjct: 488 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSK 547
Query: 123 YEKKKY 128
YE+K +
Sbjct: 548 YEEKLF 553
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 98.2 bits (243), Expect = 1e-20
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 428 SSKSKSQLTSQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 487
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
+SRV+S+ LD W E + M +GN A ++E + + T + E +IR K
Sbjct: 488 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSK 547
Query: 123 YEKKKY 128
YE+K +
Sbjct: 548 YEEKLF 553
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 97.8 bits (242), Expect = 2e-20
Identities = 47/127 (37%), Positives = 73/127 (57%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 315 SSKSKSQLTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 374
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIRD 121
+SRV+S+ LD W E + M +GN A ++E + + +P T + E +IR
Sbjct: 375 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS-SQGQTKPSIESTREEKERWIRS 433
Query: 122 KYEKKKY 128
KYE K +
Sbjct: 434 KYEHKLF 440
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 97.4 bits (241), Expect = 2e-20
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 451 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLG 510
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
H+SRV+S+ LD W E + M + N A ++E + + T + E +IR K
Sbjct: 511 PHLSRVRSLELDDWPVELRKVMSSIVNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSK 570
Query: 123 YEKKKY 128
YE+K +
Sbjct: 571 YEEKLF 576
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 96.7 bits (239), Expect = 4e-20
Identities = 45/126 (35%), Positives = 71/126 (56%), Gaps = 2/126 (1%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C DCE + P+WAS N+GV +CI C+GIH +LG
Sbjct: 428 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLG 487
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQAVEFFIRDK 122
+SRV+S+ LD W E + M +GN A ++E + + T + E +IR K
Sbjct: 488 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSK 547
Query: 123 YEKKKY 128
YE+K +
Sbjct: 548 YEEKLF 553
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 95.9 bits (237), Expect = 6e-20
Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 5/117 (4%)
Query: 15 EQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 74
E+ + +L +LL+ N CADC A P WAS+ +GVFIC+ C+GIHRN+ +S+VKSV
Sbjct: 4 ERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61
Query: 75 LDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAV---EFFIRDKYEKKKY 128
LD W Q++ M GN AR +E+ +P + RP E +IR KYE++++
Sbjct: 62 LDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEF 118
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 94.0 bits (232), Expect = 2e-19
Identities = 46/127 (36%), Positives = 73/127 (57%), Gaps = 4/127 (3%)
Query: 5 SCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLG 64
S + K+Q ++ + L + N +C D E + P+WAS N+GV +CI C+GIHR+LG
Sbjct: 451 SSKSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLG 510
Query: 65 VHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRP---QTDQAVEFFIRD 121
+SRV+S+ LD W E + M +GN A ++E + + +P T + E +IR
Sbjct: 511 TRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS-SQGQTKPSVKSTREEKERWIRS 569
Query: 122 KYEKKKY 128
KYE+K +
Sbjct: 570 KYEEKLF 576
>gi|8923763 centaurin-alpha 2 protein [Homo sapiens]
Length = 381
Score = 94.0 bits (232), Expect = 2e-19
Identities = 64/178 (35%), Positives = 95/178 (53%), Gaps = 11/178 (6%)
Query: 15 EQHQLILSKLLREED--NKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
E+++ L +LLR D N +CADC A P WAS+ +G+FIC+ C G+HRN ISRVKS
Sbjct: 5 ERNKKRLLELLRAPDTGNAHCADCGAADPDWASYKLGIFICLNCCGVHRNF-PDISRVKS 63
Query: 73 VNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAV---EFFIRDKYEKKKYY 129
V LD W ++ M GN + + +EA +P + PQ + + E +IR KYE++++
Sbjct: 64 VRLDFWDDSIVEFMIHNGNLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERREFM 123
Query: 130 -DKNAIAIT-NKEKEKKKEEKKREKEPEKPAKPLTAEKLQK---KDQQLEPKKSTSPK 182
D I++ N+E K + + + L E L K K+Q PK S K
Sbjct: 124 ADGETISLPGNREGFLWKRGRDNSQFLRRKFVLLAREGLLKYFTKEQGKSPKAVISIK 181
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 93.2 bits (230), Expect = 4e-19
Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 21/202 (10%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
+++++ + N C DC P WAS N+GV +CI+C+GIHR+LGVH S+V+S+ LD W
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
Query: 80 AEQIQCMQDMGNTKARLLYEANLPE-NFRRPQ---TDQAVEFFIRDKYEKKKYYDKNAIA 135
E ++ M ++GN +YEA + ++P + Q E +I KY +KK+ K
Sbjct: 467 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTK---- 522
Query: 136 ITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLD 195
+ + ++ + +P P KP + P+ + K P+ DL L
Sbjct: 523 -LPEIRGRRGGRGRPRGQPPVPPKP-----------SIRPRPGSLRSKPEPPSEDLGSLH 570
Query: 196 GPAVAPVTNGN-TTVPPLNDDL 216
A+ +G+ ++P + D L
Sbjct: 571 PGALLFRASGHPPSLPTMADAL 592
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 90.1 bits (222), Expect = 4e-18
Identities = 47/131 (35%), Positives = 75/131 (57%), Gaps = 6/131 (4%)
Query: 1 MATRSCREKAQ---KLNEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRC 56
+A+ C E ++ + + Q + + + +R + N C DC A P WAS N+G ICI C
Sbjct: 910 LASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIEC 969
Query: 57 AGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQA 114
+GIHRNLG H+SRV+S++LD W E + +GN A ++E++ + R + +
Sbjct: 970 SGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREE 1029
Query: 115 VEFFIRDKYEK 125
E +IR KYE+
Sbjct: 1030 RESWIRAKYEQ 1040
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 90.1 bits (222), Expect = 4e-18
Identities = 47/131 (35%), Positives = 75/131 (57%), Gaps = 6/131 (4%)
Query: 1 MATRSCREKAQ---KLNEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRC 56
+A+ C E ++ + + Q + + + +R + N C DC A P WAS N+G ICI C
Sbjct: 554 LASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIEC 613
Query: 57 AGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFR--RPQTDQA 114
+GIHRNLG H+SRV+S++LD W E + +GN A ++E++ + R + +
Sbjct: 614 SGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREE 673
Query: 115 VEFFIRDKYEK 125
E +IR KYE+
Sbjct: 674 RESWIRAKYEQ 684
>gi|31543983 ADP-ribosylation factor GTPase activating protein 2
[Homo sapiens]
Length = 521
Score = 86.7 bits (213), Expect = 4e-17
Identities = 78/281 (27%), Positives = 118/281 (41%), Gaps = 34/281 (12%)
Query: 18 QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD- 76
Q + +L NK C DC AK P WAS GVF+CI C+G+HR+LGVH+S ++S LD
Sbjct: 11 QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
Query: 77 QWTAEQIQCMQDMGNTKARLLY--------EANLPENFRRPQ----TDQAVEFFIRDKYE 124
W Q++CMQ GN A + +AN N R Q + + ++
Sbjct: 71 NWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHG 130
Query: 125 KKKYYDKNAIAITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKA 184
+ D + A+ N EKK + E + PA A EP + P
Sbjct: 131 TDLWIDNMSSAVPNHSPEKKDSDFFTE-HTQPPAWDAPA---------TEPSGTQQP--- 177
Query: 185 AEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAA 244
P+ + GL P P T+ T P + L++ +I PA G A
Sbjct: 178 -APSTESSGLAQPEHGPNTDLLGTSPKAS--LELKSSIIGKKKPAAA-KKGLGAKKGLGA 233
Query: 245 ATLSTVTSGDLDLFTEQTTKSEEV----AKKQLSKDSILSL 281
+S+ + +++ + K E AKKQ + + S+
Sbjct: 234 QKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASM 274
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 85.9 bits (211), Expect = 7e-17
Identities = 41/118 (34%), Positives = 65/118 (55%), Gaps = 2/118 (1%)
Query: 13 LNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
L + + I+ + R N C DC + P W S N+G+ CI C+GIHR +GVHISR++S
Sbjct: 434 LEDLTKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQS 493
Query: 73 VNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYD 130
+ LD+ ++ +++GN + EANLP P+ + + +R +Y KY D
Sbjct: 494 LELDKLGTSELLLAKNVGNNSFNDIMEANLPS--PSPKPTPSSDMTVRKEYITAKYVD 549
>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
isoform 2 [Homo sapiens]
Length = 472
Score = 80.9 bits (198), Expect = 2e-15
Identities = 43/92 (46%), Positives = 56/92 (60%), Gaps = 2/92 (2%)
Query: 14 NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
++Q L + K LR NK C DC AK P WAS GVF+CI C+G HR+LGVH+S ++S
Sbjct: 5 SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
Query: 73 VNLD-QWTAEQIQCMQDMGNTKARLLYEANLP 103
LD W+ Q++CMQ GN A L +P
Sbjct: 65 TELDSNWSWFQLRCMQVGGNASALWLDSCVVP 96
>gi|214829673 ADP-ribosylation factor GTPase activating protein 3
isoform 1 [Homo sapiens]
Length = 516
Score = 80.1 bits (196), Expect = 4e-15
Identities = 41/83 (49%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 14 NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72
++Q L + K LR NK C DC AK P WAS GVF+CI C+G HR+LGVH+S ++S
Sbjct: 5 SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
Query: 73 VNLD-QWTAEQIQCMQDMGNTKA 94
LD W+ Q++CMQ GN A
Sbjct: 65 TELDSNWSWFQLRCMQVGGNASA 87
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 79.3 bits (194), Expect = 6e-15
Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 9/123 (7%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
I+S++ R N C DC A P W S N+G+ CI C+GIHR LGVH SR++S+ LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLG 482
Query: 80 AEQIQCMQDMGNTKARLLYEANLP-ENFRRP--------QTDQAVEFFIRDKYEKKKYYD 130
++ +++GN + E LP E+ +P + D +I +Y +KK+ D
Sbjct: 483 TSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHAD 542
Query: 131 KNA 133
A
Sbjct: 543 NAA 545
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 79.3 bits (194), Expect = 6e-15
Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 9/123 (7%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
I+S++ R N C DC A P W S N+G+ CI C+GIHR LGVH SR++S+ LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLG 482
Query: 80 AEQIQCMQDMGNTKARLLYEANLP-ENFRRP--------QTDQAVEFFIRDKYEKKKYYD 130
++ +++GN + E LP E+ +P + D +I +Y +KK+ D
Sbjct: 483 TSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHAD 542
Query: 131 KNA 133
A
Sbjct: 543 NAA 545
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 77.4 bits (189), Expect = 2e-14
Identities = 39/113 (34%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Query: 18 QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ 77
+L+++++ N C DC A P W S N+GV CI+C+G+HR LGV SR++S+ LD
Sbjct: 417 KLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDL 476
Query: 78 WTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYD 130
++ +MGNT + EA LP + P+ + R Y KY +
Sbjct: 477 LGPSELLLALNMGNTSFNEVMEAQLPSH-GGPKPSAESDMGTRRDYIMAKYVE 528
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 77.4 bits (189), Expect = 2e-14
Identities = 39/113 (34%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Query: 18 QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ 77
+L+++++ N C DC A P W S N+GV CI+C+G+HR LGV SR++S+ LD
Sbjct: 426 KLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDL 485
Query: 78 WTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYD 130
++ +MGNT + EA LP + P+ + R Y KY +
Sbjct: 486 LGPSELLLALNMGNTSFNEVMEAQLPSH-GGPKPSAESDMGTRRDYIMAKYVE 537
>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
2 [Homo sapiens]
Length = 1704
Score = 77.0 bits (188), Expect = 3e-14
Identities = 46/129 (35%), Positives = 70/129 (54%), Gaps = 6/129 (4%)
Query: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ-- 77
+ K+ E N+ CADC+A P WAS N+ V IC +CAG HR+LG S+V+S+ +D
Sbjct: 687 VAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASI 746
Query: 78 WTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVE---FFIRDKYEKKKYYDKNAI 134
W+ E I+ +GN +A + NL ++ D VE FI KY++ K+
Sbjct: 747 WSNELIELFIVIGNKRANDFWAGNLQKD-EELHMDSPVEKRKNFITQKYKEGKFRKTLLA 805
Query: 135 AITNKEKEK 143
++T +E K
Sbjct: 806 SLTKEELNK 814
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,356,231
Number of Sequences: 37866
Number of extensions: 1098338
Number of successful extensions: 12278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 240
Number of HSP's successfully gapped in prelim test: 544
Number of HSP's that attempted gapping in prelim test: 8057
Number of HSP's gapped (non-prelim): 3349
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.