BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sapiens] (859 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 1705 0.0 gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sa... 1705 0.0 gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sap... 1705 0.0 gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 1696 0.0 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 52 2e-06 gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens] 50 1e-05 gi|109240550 paraspeckle protein 1 [Homo sapiens] 49 3e-05 gi|221139761 zinc finger protein 853 [Homo sapiens] 48 4e-05 gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 47 6e-05 gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens] 47 1e-04 gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 46 1e-04 gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 46 1e-04 gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 46 1e-04 gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 46 1e-04 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 2e-04 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 45 2e-04 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 45 3e-04 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 45 3e-04 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 45 3e-04 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 45 3e-04 gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 45 3e-04 gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 45 3e-04 gi|112421108 capicua homolog [Homo sapiens] 45 3e-04 gi|221219020 NYD-SP11 protein [Homo sapiens] 45 4e-04 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 45 4e-04 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 45 4e-04 gi|41406089 SRY-box 13 [Homo sapiens] 45 4e-04 gi|22758136 MAP7 domain containing 2 [Homo sapiens] 45 4e-04 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 44 5e-04 gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 44 6e-04 >gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] Length = 1090 Score = 1705 bits (4416), Expect = 0.0 Identities = 859/859 (100%), Positives = 859/859 (100%) Query: 1 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 60 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL Sbjct: 232 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 291 Query: 61 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 120 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS Sbjct: 292 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 351 Query: 121 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 180 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE Sbjct: 352 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 411 Query: 181 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 240 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK Sbjct: 412 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 471 Query: 241 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 300 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA Sbjct: 472 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 531 Query: 301 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 360 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG Sbjct: 532 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 591 Query: 361 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 420 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE Sbjct: 592 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 651 Query: 421 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 480 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV Sbjct: 652 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 711 Query: 481 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 540 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV Sbjct: 712 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 771 Query: 541 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 600 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ Sbjct: 772 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 831 Query: 601 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 660 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL Sbjct: 832 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 891 Query: 661 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 720 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS Sbjct: 892 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 951 Query: 721 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 780 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT Sbjct: 952 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 1011 Query: 781 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 840 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA Sbjct: 1012 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 1071 Query: 841 LALRWEAGIYANQEEEDNE 859 LALRWEAGIYANQEEEDNE Sbjct: 1072 LALRWEAGIYANQEEEDNE 1090 >gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sapiens] Length = 859 Score = 1705 bits (4416), Expect = 0.0 Identities = 859/859 (100%), Positives = 859/859 (100%) Query: 1 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 60 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL Sbjct: 1 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 60 Query: 61 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 120 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS Sbjct: 61 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 120 Query: 121 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 180 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE Sbjct: 121 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 180 Query: 181 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 240 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK Sbjct: 181 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 240 Query: 241 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 300 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA Sbjct: 241 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 300 Query: 301 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 360 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG Sbjct: 301 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 360 Query: 361 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 420 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE Sbjct: 361 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 420 Query: 421 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 480 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV Sbjct: 421 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 480 Query: 481 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 540 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV Sbjct: 481 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 540 Query: 541 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 600 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ Sbjct: 541 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 600 Query: 601 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 660 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL Sbjct: 601 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 660 Query: 661 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 720 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS Sbjct: 661 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 720 Query: 721 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 780 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT Sbjct: 721 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 780 Query: 781 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 840 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA Sbjct: 781 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 840 Query: 841 LALRWEAGIYANQEEEDNE 859 LALRWEAGIYANQEEEDNE Sbjct: 841 LALRWEAGIYANQEEEDNE 859 >gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sapiens] Length = 948 Score = 1705 bits (4416), Expect = 0.0 Identities = 859/859 (100%), Positives = 859/859 (100%) Query: 1 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 60 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL Sbjct: 90 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 149 Query: 61 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 120 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS Sbjct: 150 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 209 Query: 121 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 180 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE Sbjct: 210 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 269 Query: 181 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 240 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK Sbjct: 270 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 329 Query: 241 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 300 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA Sbjct: 330 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 389 Query: 301 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 360 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG Sbjct: 390 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 449 Query: 361 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 420 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE Sbjct: 450 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 509 Query: 421 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 480 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV Sbjct: 510 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 569 Query: 481 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 540 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV Sbjct: 570 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 629 Query: 541 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 600 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ Sbjct: 630 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 689 Query: 601 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 660 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL Sbjct: 690 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 749 Query: 661 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 720 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS Sbjct: 750 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 809 Query: 721 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 780 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT Sbjct: 810 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 869 Query: 781 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 840 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA Sbjct: 870 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 929 Query: 841 LALRWEAGIYANQEEEDNE 859 LALRWEAGIYANQEEEDNE Sbjct: 930 LALRWEAGIYANQEEEDNE 948 >gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] Length = 1103 Score = 1696 bits (4392), Expect = 0.0 Identities = 859/872 (98%), Positives = 859/872 (98%), Gaps = 13/872 (1%) Query: 1 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 60 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL Sbjct: 232 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 291 Query: 61 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 120 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS Sbjct: 292 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 351 Query: 121 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 180 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE Sbjct: 352 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 411 Query: 181 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 240 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK Sbjct: 412 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 471 Query: 241 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 300 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA Sbjct: 472 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 531 Query: 301 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 360 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG Sbjct: 532 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 591 Query: 361 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 420 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE Sbjct: 592 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 651 Query: 421 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 480 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV Sbjct: 652 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 711 Query: 481 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 540 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV Sbjct: 712 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 771 Query: 541 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 600 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ Sbjct: 772 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 831 Query: 601 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 660 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL Sbjct: 832 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 891 Query: 661 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 720 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS Sbjct: 892 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 951 Query: 721 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 780 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT Sbjct: 952 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 1011 Query: 781 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSS------------- 827 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSS Sbjct: 1012 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSE 1071 Query: 828 VLEATRVNRRKSALALRWEAGIYANQEEEDNE 859 VLEATRVNRRKSALALRWEAGIYANQEEEDNE Sbjct: 1072 VLEATRVNRRKSALALRWEAGIYANQEEEDNE 1103 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 52.0 bits (123), Expect = 2e-06 Identities = 57/235 (24%), Positives = 93/235 (39%), Gaps = 41/235 (17%) Query: 91 SPPVHEATQPEPTERTASRQAPPHI-ELSNSSP----DPMAEAERTNGHSPSQP-RDALG 144 S P + +PEP + S +AP H+ + P P+ N P P +D Sbjct: 1122 SEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK 1181 Query: 145 DSLQVPVSPSSTTSSRCSSRDGEFTL---TTLKKEAKFELRAFHEDKKPSKLFEDDEHEK 201 + PV+P + TT AK +F + ++ ++ E +E EK Sbjct: 1182 QEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAR--EKEEREK 1239 Query: 202 EQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLES 261 ++ E E EKER +++ + + DE+ LE Sbjct: 1240 ------ALKAQAEHAEKEKERL----------------------RQERMRSREDEDALEQ 1271 Query: 262 HKKYKERKERRAQQEQLLLQKQLQQQQQQPP--SQLCTAPASSHERASMIDKAKE 314 ++ E RR +Q+Q Q+Q QQQQQQ + T A S + SM+D+ +E Sbjct: 1272 ARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRE 1326 >gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens] Length = 768 Score = 49.7 bits (117), Expect = 1e-05 Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 40/337 (11%) Query: 102 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQP--------RDALGDSLQVPVS- 152 P + +Q NS A E NG SP D + LQ S Sbjct: 432 PLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSG 491 Query: 153 ---PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV 209 PS T+ + DG T T+ L + K + + E+ I+ Sbjct: 492 VCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTA 548 Query: 210 RPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLES 261 P ++L R L++ + V + I K + P P T L + LE Sbjct: 549 GPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEE 605 Query: 262 HKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI 321 +++ ERK++ +++ L + +Q+++ PP Q PA H S K +ED+V E Sbjct: 606 YRREVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPT 658 Query: 322 ---DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGG 378 D AA + L + S ++ P L + +RP + + P Sbjct: 659 TGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAP 718 Query: 379 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 415 E++ SA + GA P + GS G + S+ K+ Sbjct: 719 VAEEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 751 Score = 32.0 bits (71), Expect = 2.5 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%) Query: 567 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 625 EYQ ++V D+ + + R+ +Q+G E ++EA S Q Sbjct: 580 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 639 Query: 626 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 668 P S+P++ + D++P+ +D P LP + P P Sbjct: 640 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680 >gi|109240550 paraspeckle protein 1 [Homo sapiens] Length = 523 Score = 48.5 bits (114), Expect = 3e-05 Identities = 68/305 (22%), Positives = 116/305 (38%), Gaps = 44/305 (14%) Query: 153 PSSTTSSRCSSRDGEFTLTTLKKEAKFE-LRAFH-EDKKPSKLFEDDE--HEKEQYCIRK 208 P+ RC DG F LTT + E + F ED P KL + + H++ + R Sbjct: 208 PARKALERCG--DGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQYHKEREQPPRF 265 Query: 209 VRPS----------EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEH 258 +P + + E+EK++RE + +EK E H Sbjct: 266 AQPGTFEFEYASRWKALDEMEKQQREQVDRNI------------REAKEKLEAEMEAARH 313 Query: 259 LESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERAS---MIDKAKED 315 H+ R++ +QE+L ++L+ Q+ Q Q+ H R + + +E+ Sbjct: 314 --EHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEE 371 Query: 316 IVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPS 375 + +Q F MEN Q + G PR +I +G S P N PP Sbjct: 372 LRRQQEGFKP-----NYMENREQEMRMGDMGPR-GAIN-----MGDAFSPAPAGNQGPPP 420 Query: 376 VGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDG 435 + G ++ A+ PG P A + G +++ +GP S++ + G Sbjct: 421 MMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMG 480 Query: 436 EFTSA 440 T + Sbjct: 481 SRTGS 485 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 47.8 bits (112), Expect = 4e-05 Identities = 61/278 (21%), Positives = 123/278 (44%), Gaps = 38/278 (13%) Query: 81 PGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAE-AERTNG------ 133 PG L GG S + EP ER +S Q P + S+P +E AE T Sbjct: 37 PGPDTLSGG-SGGSESQEEEEPQERNSSPQRP-----AVSAPVGASEIAEETRPGQRELQ 90 Query: 134 -----HSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDK 188 P + + LQ P P + +DG+ L+ L++E + H++ Sbjct: 91 LQQLEQQPEPQQQPQHEQLQQP-QPHLELQQQ-PQQDGQQQLSQLQQEKHQSVH--HQEL 146 Query: 189 KPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEK 248 KP H+++Q ++V +E L++++ +L QA ++ Q++ Sbjct: 147 KPELQLM---HQQQQLQPQQV---QEQQRLQQQQEQLQTQQAQEQQV--------LQQQE 192 Query: 249 TIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ--QPPSQLCTAPASSHERA 306 +++Q+ E+ L ++ + ++++ QQ++ L Q+Q QQQQ+ Q QL + Sbjct: 193 QLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQ 252 Query: 307 SMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQ 344 ++ + + + + ++ A+ Q QL+ ++ + + Q Sbjct: 253 QLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQ 290 Score = 38.9 bits (89), Expect = 0.021 Identities = 46/239 (19%), Positives = 100/239 (41%), Gaps = 28/239 (11%) Query: 198 EHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQL--- 254 E ++ Q + + +E L+ +++++ L + Q + + P +E+ +E +L Sbjct: 268 EQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPV 327 Query: 255 ---DEEHLESHKKYKERK-ERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMID 310 E+ LE ++ ER+ E QQEQ LQ +LQ++ QQ QL ++ ++ Sbjct: 328 DLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQL-------EQQQQQLE 380 Query: 311 KAKEDIVTEQIDFSAARKQFQL----------MENSRQAVAKGQSTP----RLFSIKPFY 356 + + + ++ A +++ QL +E A G + P + P Y Sbjct: 381 QQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGY 440 Query: 357 RPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 415 + + + P ++ GP + + A+ ++ A + P+ G G S+ + Sbjct: 441 VVVQELMVLPAVAAPAVVAIPGPAGSAALTPARQRRRRRARDRPTICGECGKGFSRSTD 499 >gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] Length = 1312 Score = 47.4 bits (111), Expect = 6e-05 Identities = 83/367 (22%), Positives = 134/367 (36%), Gaps = 57/367 (15%) Query: 101 EPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSR 160 +PTER Q HI+ S E E +S S+ D DS PSS + Sbjct: 292 QPTERQVRIQLKDHIDRSRKKRGEKEETEYE--YSGSEEED---DSHGEEGEPSSIMNV- 345 Query: 161 CSSRDGEFTLTT----LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEML 216 GE TL L++E K A K+ +L + + + E + + + + Sbjct: 346 ----PGESTLRREFLRLQQENKSNSEAL---KQQQQLQQQQQRDPEAHIKHLLHQRQRRI 398 Query: 217 ELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEE------QLDEEHLESHKKYK---- 266 E +KE R + Q ++ K Q++ +E+ + + E ++YK Sbjct: 399 EEQKEERRRVEEQQRRERE--QRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQL 456 Query: 267 ------ERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASM------IDKAKE 314 ER +R+ QQE L+ QQQQQQ + +R + ++ A + Sbjct: 457 EEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADK 516 Query: 315 DIVTEQIDFSAARKQFQLMENSRQAVAKGQST---PRLFSIKPFYRPLGSVNSDKPLTNP 371 +++ R + +NS A +K ST P + P P G ++ P+ P Sbjct: 517 PAWAREVE---ERTRMNKQQNSPLAKSKPGSTGPEPPIPQASP--GPPGPLSQTPPMQRP 571 Query: 372 RPPSVG-------GPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKR 424 P G P + A A P A+ P+A S + P SE Sbjct: 572 VEPQEGPHKSLQDQPTRNLAAFPASHDPDP-AIPAPTATPSARGAVIRQNSDPTSEGPGP 630 Query: 425 GPLSKLW 431 P W Sbjct: 631 SPNPPAW 637 Score = 31.6 bits (70), Expect = 3.3 Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 3/149 (2%) Query: 647 EDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMV 706 ED + E G P + V + E R + S SEA L+ L Q+ D Sbjct: 329 EDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSN-SEA--LKQQQQLQQQQQRDPEA 385 Query: 707 GPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTA 766 L ++QR + +EE R +E++ + QR++ + Q R ++ +L + A Sbjct: 386 HIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQA 445 Query: 767 PGKIEKVKPPPSPTTEGPSLQPDLAPEEA 795 + E + + LQ L E A Sbjct: 446 EREQEYKRKQLEEQRQSERLQRQLQQEHA 474 >gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens] Length = 737 Score = 46.6 bits (109), Expect = 1e-04 Identities = 63/275 (22%), Positives = 109/275 (39%), Gaps = 30/275 (10%) Query: 152 SPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRP 211 SP S T + + DG T T+ L + K + + E+ I+ P Sbjct: 465 SPKSKT--KWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTAGP 519 Query: 212 SEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLESHK 263 ++L R L++ + V + I K + P P T L + LE ++ Sbjct: 520 QSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEEYR 576 Query: 264 KYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI-- 321 + ERK++ +++ L + +Q+++ PP Q PA H S K +ED+V E Sbjct: 577 REVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPTTG 629 Query: 322 -DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPP 380 D AA + L + S ++ P L + +RP + + P Sbjct: 630 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 689 Query: 381 EDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 415 E++ SA + GA P + GS G + S+ K+ Sbjct: 690 EEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 720 Score = 32.0 bits (71), Expect = 2.5 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%) Query: 567 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 625 EYQ ++V D+ + + R+ +Q+G E ++EA S Q Sbjct: 549 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 608 Query: 626 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 668 P S+P++ + D++P+ +D P LP + P P Sbjct: 609 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 649 >gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sapiens] Length = 1297 Score = 46.2 bits (108), Expect = 1e-04 Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%) Query: 95 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 153 H + +P ER Q HI+ + E E +G + + G+ + P Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345 Query: 154 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 213 +T R +F L + + E A + + E++EH+++ R+ R Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394 Query: 214 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 271 +E +KE+R + Q + EK + +Q + E +++ R+E R Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438 Query: 272 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 331 RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q + Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494 Query: 332 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 367 + ++ + R KP Y G S+KP Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531 >gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sapiens] Length = 1305 Score = 46.2 bits (108), Expect = 1e-04 Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%) Query: 95 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 153 H + +P ER Q HI+ + E E +G + + G+ + P Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345 Query: 154 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 213 +T R +F L + + E A + + E++EH+++ R+ R Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394 Query: 214 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 271 +E +KE+R + Q + EK + +Q + E +++ R+E R Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438 Query: 272 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 331 RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q + Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494 Query: 332 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 367 + ++ + R KP Y G S+KP Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531 >gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sapiens] Length = 1352 Score = 46.2 bits (108), Expect = 1e-04 Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%) Query: 95 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 153 H + +P ER Q HI+ + E E +G + + G+ + P Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345 Query: 154 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 213 +T R +F L + + E A + + E++EH+++ R+ R Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394 Query: 214 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 271 +E +KE+R + Q + EK + +Q + E +++ R+E R Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438 Query: 272 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 331 RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q + Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494 Query: 332 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 367 + ++ + R KP Y G S+KP Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531 >gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sapiens] Length = 1360 Score = 46.2 bits (108), Expect = 1e-04 Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%) Query: 95 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 153 H + +P ER Q HI+ + E E +G + + G+ + P Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345 Query: 154 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 213 +T R +F L + + E A + + E++EH+++ R+ R Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394 Query: 214 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 271 +E +KE+R + Q + EK + +Q + E +++ R+E R Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438 Query: 272 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 331 RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q + Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494 Query: 332 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 367 + ++ + R KP Y G S+KP Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 45.8 bits (107), Expect = 2e-04 Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 9/116 (7%) Query: 175 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 234 + AKF L + +++ +E +EQ +K+R EE + ++ER +R Q K Sbjct: 256 ERAKFLLPQVQTNTLQEEMWRQEEELREQE--KKIRKQEEKMWRQEER---LREQEGKMR 310 Query: 235 PGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 W QEK + EQ ++E E K+ +E+KE R Q+EQ+ Q++ +Q++ Sbjct: 311 EQEEKMW---RQEKRLREQ-EKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362 Score = 38.9 bits (89), Expect = 0.021 Identities = 33/140 (23%), Positives = 73/140 (52%), Gaps = 21/140 (15%) Query: 174 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCI----RKVRPSEEMLELEKE--RRELIR 227 ++E +++ + E K+ KL+E ++ ++++ I K+R EEM EK+ R+E +R Sbjct: 483 QEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540 Query: 228 SQA------VKKNPGIAAKWWNPPQ--EKTIEEQL-----DEEHLESHKKYKERKERRAQ 274 Q +K K W+ + EK +EQ EE + ++ +ER+++ + Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600 Query: 275 QEQLLLQKQLQQQQQQPPSQ 294 +E+++ +++ + Q+Q+ Q Sbjct: 601 EEEMMREQEEKMQEQEEKMQ 620 Score = 38.9 bits (89), Expect = 0.021 Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 17/124 (13%) Query: 174 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE---LIRSQA 230 +K + E + + ++K K E EK+ + K+R E M E EK+ RE ++R Q Sbjct: 677 EKMQEQEEKIWEQEKMEKKT---QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733 Query: 231 VKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 K QE+ ++EQ +EE E +K E++E+ +Q++L QK+ + ++ Sbjct: 734 EKMQE----------QEEKMQEQ-EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 782 Query: 291 PPSQ 294 Q Sbjct: 783 MQEQ 786 Score = 37.4 bits (85), Expect = 0.060 Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 19/133 (14%) Query: 186 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE---LIRSQAVKKNPGIAAKWW 242 E++ K E ++ +Q K+R E M E EK+ RE ++R Q K Sbjct: 564 EERMEKKTQEQEKKTWDQE--EKMREEERMREREKKMREEEEMMREQEEKMQE------- 614 Query: 243 NPPQEKTIEEQLDEEHLESHKKYKERKERR-AQQEQLLLQKQLQQQQQQPPSQLCTAPAS 301 QE+ ++EQ +E+ E +K +E++E+ Q+E++ Q++ +QQ+ P Q Sbjct: 615 ---QEEKMQEQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ--KEKLW 668 Query: 302 SHERASMIDKAKE 314 HE+ +K +E Sbjct: 669 EHEKMQEQEKMQE 681 Score = 35.4 bits (80), Expect = 0.23 Identities = 26/112 (23%), Positives = 56/112 (50%), Gaps = 14/112 (12%) Query: 188 KKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEK-ERRELIRSQAVKKNPGIAAKWWNPPQ 246 ++ K++E +E EQ R E++ E EK + +E ++ Q K W Sbjct: 642 EQEEKMWEQEEKMWEQQ--RLPEQKEKLWEHEKMQEQEKMQEQEEKI-------WEQEKM 692 Query: 247 EKTIEEQ----LDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 EK +EQ D+E + + +ER+++ ++E+++ +++ + Q+Q+ Q Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744 Score = 34.3 bits (77), Expect = 0.51 Identities = 33/131 (25%), Positives = 62/131 (47%), Gaps = 9/131 (6%) Query: 164 RDGEFTLTTLKKEAKF--ELRAFHED--KKPSKLFEDDEHEKEQYCIRKVRPSEEMLELE 219 R+ E L +KE + ELR E ++ K++E +E +EQ + R E + E E Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQE-EKMWRQEERLWEQE 382 Query: 220 KERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLL 279 K+ RE Q K W + + EE++ E+ + K R+E++ Q+++ Sbjct: 383 KQMRE----QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438 Query: 280 LQKQLQQQQQQ 290 + Q ++ Q++ Sbjct: 439 TRDQEEKMQEE 449 Score = 34.3 bits (77), Expect = 0.51 Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 15/96 (15%) Query: 195 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQL 254 ED E+E+ K+R E+ + ++ER E KK K W+ ++ EE++ Sbjct: 543 EDQMWEQEE----KMRDQEQKMWDQEERME-------KKTQEQEKKTWDQEEKMREEERM 591 Query: 255 DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 E KK +E +E +QE+ + +++ + Q+Q+ Sbjct: 592 RER----EKKMREEEEMMREQEEKMQEQEEKMQEQE 623 Score = 33.9 bits (76), Expect = 0.66 Identities = 30/123 (24%), Positives = 64/123 (52%), Gaps = 13/123 (10%) Query: 176 EAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVK--- 232 E K +L + ++ K++E +E ++Q K+R EE + ++E+ +R Q K Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQE--EKMRGQEEKMRGQEEK---MRGQEEKMWG 826 Query: 233 ---KNPGIAAKWWNPPQEKTIEEQLDEEHLESHK-KYKERKER-RAQQEQLLLQKQLQQQ 287 K G K W ++ +E+ EE ++ + K +E++E+ R Q+E++ Q++ + Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRG 886 Query: 288 QQQ 290 Q++ Sbjct: 887 QEE 889 Score = 32.7 bits (73), Expect = 1.5 Identities = 22/97 (22%), Positives = 50/97 (51%), Gaps = 2/97 (2%) Query: 198 EHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEE 257 E EK + K+R ++M E EK+ R+ + + +++ I + +E+ + +E+ Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRD--QEEKMQEEERIREREKKMREEEETMREQEEK 472 Query: 258 HLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 + + E++E+ QQ++L QK+ +Q++ Q Sbjct: 473 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509 Score = 31.2 bits (69), Expect = 4.3 Identities = 26/111 (23%), Positives = 59/111 (53%), Gaps = 8/111 (7%) Query: 180 ELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAA 239 E R ++K ++ + E +K Q +K R EE ++ E+ RE R + +++ Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE--REKKMREEEETMR 467 Query: 240 KWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 + QE+ +++Q +E E +K +++ Q+E+L Q+++Q+Q+++ Sbjct: 468 E-----QEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512 Score = 30.4 bits (67), Expect = 7.3 Identities = 23/103 (22%), Positives = 50/103 (48%), Gaps = 5/103 (4%) Query: 197 DEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEE---- 252 D+ E+ ++R EE + +++ E + +K K +EK EE Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453 Query: 253 QLDEEHLESHKKYKERKER-RAQQEQLLLQKQLQQQQQQPPSQ 294 + +++ E + +E++E+ + Q+E + Q++ + QQQ+ P Q Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 45.4 bits (106), Expect = 2e-04 Identities = 69/321 (21%), Positives = 122/321 (38%), Gaps = 57/321 (17%) Query: 100 PEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSS 159 P P+ + APP E P AE S P A PV+PS + Sbjct: 545 PAPSPAPSPTPAPPQKE------QPPAETPTDAAVLTSPPAPA------PPVTPSKPMAG 592 Query: 160 RCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELE 219 + L +++A+ + E +E E+ R R EE L E Sbjct: 593 TTDREEATRLLAEKRRQAREQR-------------EREEQERRLQAERDKRMREEQLARE 639 Query: 220 KERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER-RAQQEQL 278 E R ++A ++ A +EK EQ ++E L+ K+ E + R A++++L Sbjct: 640 AEARAEREAEARRREEQEA-------REKAQAEQEEQERLQKQKEEAEARSREEAERQRL 692 Query: 279 LLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 338 +K QQQ+Q+ ER +++ + T + + S +++ ++S++ Sbjct: 693 EREKHFQQQEQE-----------RQERRKRLEEIMKR--TRKSEVSETKQK----QDSKE 735 Query: 339 AVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALE 398 A A G S + +++ L K P+ P P ++ AS G + Sbjct: 736 ANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQ------ 789 Query: 399 TPSAAGSQGNTASQGKEGPYS 419 P A + ++ G G S Sbjct: 790 -PLPAHQENGFSTNGPSGDKS 809 Score = 40.0 bits (92), Expect = 0.009 Identities = 48/213 (22%), Positives = 87/213 (40%), Gaps = 23/213 (10%) Query: 86 LVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPD------PMAEAERTNGHSPSQP 139 L G P V T PEP +PP +S PD P + ++ P +P Sbjct: 9 LGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEP 68 Query: 140 RDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEH 199 G P P + S + G ++A+ R+ P+ + D Sbjct: 69 ESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRS--SQPSPTAVPASDSP 126 Query: 200 EKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK--WWNPPQEKTIEEQLDEE 257 +Q +V+ + E +L KERRE ++ +AAK W +EK + L E+ Sbjct: 127 PTKQ----EVKKAGERHKLAKERRE-------ERAKYLAAKKAVWLEKEEKA--KALREK 173 Query: 258 HLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 L+ ++ E + +A+Q + L+++ +Q+ ++ Sbjct: 174 QLQERRRRLEEQRLKAEQRRAALEERQRQKLEK 206 Score = 31.2 bits (69), Expect = 4.3 Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 22/147 (14%) Query: 626 PPQVSSPVQEKRD---VLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFS 682 PPQ SP E + P + P + R R P P P +E + G Sbjct: 81 PPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHK 140 Query: 683 KYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQV 742 E E R A LA +++ +E+E +A RE++L+ +R+ Sbjct: 141 LAKERREER--AKYLAAKKA-----------------VWLEKEEKAKALREKQLQERRRR 181 Query: 743 LQSTQSPRTKNAPSLPSRTCYKTAPGK 769 L+ + + +L R K K Sbjct: 182 LEEQRLKAEQRRAALEERQRQKLEKNK 208 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 45.1 bits (105), Expect = 3e-04 Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%) Query: 195 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 252 E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE Sbjct: 803 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 857 Query: 253 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 295 +++EE H E +K KE ++R+ QQE L +Q QQQQQ +L Sbjct: 858 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 917 Query: 296 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 338 ++ + + +++ + +I ++ QL E R+ Sbjct: 918 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960 Score = 37.7 bits (86), Expect = 0.046 Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Query: 213 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 272 E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R Sbjct: 718 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 773 Query: 273 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 332 ++E+L +KQ + ++Q ++ E ++A + + + RKQ +L Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833 Query: 333 MENSRQAVAK 342 + + AK Sbjct: 834 LRKQEEEAAK 843 Score = 35.4 bits (80), Expect = 0.23 Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%) Query: 175 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 234 +E LR E++K +L E ++++ +R+ + +E L +++++ + Q + Sbjct: 863 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 916 Query: 235 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 289 ++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ Sbjct: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976 Query: 290 Q 290 Q Sbjct: 977 Q 977 Score = 32.3 bits (72), Expect = 1.9 Identities = 16/38 (42%), Positives = 23/38 (60%) Query: 257 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 E E K++ ER+ ++ +Q Q+ QQQQQQPP Q Sbjct: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1214 Score = 31.6 bits (70), Expect = 3.3 Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%) Query: 186 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 240 E K +KL E + E E R+ + EL +++ E++R Q ++ +A + Sbjct: 724 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 782 Query: 241 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 + E+++ +EE + + + +ERR ++E+ Q++L ++Q++ Sbjct: 783 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 839 Score = 31.2 bits (69), Expect = 4.3 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 252 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 ++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q Sbjct: 1179 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1218 Score = 30.0 bits (66), Expect = 9.6 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 25/123 (20%) Query: 714 RKQRTLSMIE----EEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGK 769 + Q TLS+ E EE R Q REE+ ++QR+++++ Q + + L + G Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-------SGWGN 985 Query: 770 IEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVL 829 + K PS TT+ ++ EEA MQ + + H+ R R + S L Sbjct: 986 VSK----PSGTTKS---LLEIQQEEA-------RQMQKQQQQQQQHQQPNRARNNTHSNL 1031 Query: 830 EAT 832 + Sbjct: 1032 HTS 1034 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 45.1 bits (105), Expect = 3e-04 Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%) Query: 195 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 252 E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE Sbjct: 830 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 884 Query: 253 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 295 +++EE H E +K KE ++R+ QQE L +Q QQQQQ +L Sbjct: 885 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 944 Query: 296 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 338 ++ + + +++ + +I ++ QL E R+ Sbjct: 945 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 987 Score = 37.7 bits (86), Expect = 0.046 Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Query: 213 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 272 E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R Sbjct: 745 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 800 Query: 273 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 332 ++E+L +KQ + ++Q ++ E ++A + + + RKQ +L Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860 Query: 333 MENSRQAVAK 342 + + AK Sbjct: 861 LRKQEEEAAK 870 Score = 35.4 bits (80), Expect = 0.23 Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%) Query: 175 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 234 +E LR E++K +L E ++++ +R+ + +E L +++++ + Q + Sbjct: 890 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 943 Query: 235 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 289 ++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ Sbjct: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003 Query: 290 Q 290 Q Sbjct: 1004 Q 1004 Score = 32.3 bits (72), Expect = 1.9 Identities = 16/38 (42%), Positives = 23/38 (60%) Query: 257 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 E E K++ ER+ ++ +Q Q+ QQQQQQPP Q Sbjct: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1241 Score = 31.6 bits (70), Expect = 3.3 Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%) Query: 186 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 240 E K +KL E + E E R+ + EL +++ E++R Q ++ +A + Sbjct: 751 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 809 Query: 241 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 + E+++ +EE + + + +ERR ++E+ Q++L ++Q++ Sbjct: 810 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 866 Score = 31.2 bits (69), Expect = 4.3 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 252 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 ++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q Sbjct: 1206 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1245 Score = 30.0 bits (66), Expect = 9.6 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 25/123 (20%) Query: 714 RKQRTLSMIE----EEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGK 769 + Q TLS+ E EE R Q REE+ ++QR+++++ Q + + L + G Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-------SGWGN 1012 Query: 770 IEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVL 829 + K PS TT+ ++ EEA MQ + + H+ R R + S L Sbjct: 1013 VSK----PSGTTKS---LLEIQQEEA-------RQMQKQQQQQQQHQQPNRARNNTHSNL 1058 Query: 830 EAT 832 + Sbjct: 1059 HTS 1061 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 45.1 bits (105), Expect = 3e-04 Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%) Query: 195 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 252 E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE Sbjct: 809 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 863 Query: 253 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 295 +++EE H E +K KE ++R+ QQE L +Q QQQQQ +L Sbjct: 864 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923 Query: 296 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 338 ++ + + +++ + +I ++ QL E R+ Sbjct: 924 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 966 Score = 37.7 bits (86), Expect = 0.046 Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Query: 213 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 272 E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R Sbjct: 724 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 779 Query: 273 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 332 ++E+L +KQ + ++Q ++ E ++A + + + RKQ +L Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839 Query: 333 MENSRQAVAK 342 + + AK Sbjct: 840 LRKQEEEAAK 849 Score = 35.4 bits (80), Expect = 0.23 Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%) Query: 175 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 234 +E LR E++K +L E ++++ +R+ + +E L +++++ + Q + Sbjct: 869 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 922 Query: 235 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 289 ++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ Sbjct: 923 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982 Query: 290 Q 290 Q Sbjct: 983 Q 983 Score = 32.3 bits (72), Expect = 1.9 Identities = 16/38 (42%), Positives = 23/38 (60%) Query: 257 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 E E K++ ER+ ++ +Q Q+ QQQQQQPP Q Sbjct: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1220 Score = 31.6 bits (70), Expect = 3.3 Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%) Query: 186 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 240 E K +KL E + E E R+ + EL +++ E++R Q ++ +A + Sbjct: 730 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 788 Query: 241 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 + E+++ +EE + + + +ERR ++E+ Q++L ++Q++ Sbjct: 789 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845 Score = 31.2 bits (69), Expect = 4.3 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 252 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 ++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q Sbjct: 1185 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1224 Score = 30.0 bits (66), Expect = 9.6 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 25/123 (20%) Query: 714 RKQRTLSMIE----EEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGK 769 + Q TLS+ E EE R Q REE+ ++QR+++++ Q + + L + G Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-------SGWGN 991 Query: 770 IEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVL 829 + K PS TT+ ++ EEA MQ + + H+ R R + S L Sbjct: 992 VSK----PSGTTKS---LLEIQQEEA-------RQMQKQQQQQQQHQQPNRARNNTHSNL 1037 Query: 830 EAT 832 + Sbjct: 1038 HTS 1040 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 45.1 bits (105), Expect = 3e-04 Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%) Query: 195 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 252 E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE Sbjct: 809 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 863 Query: 253 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 295 +++EE H E +K KE ++R+ QQE L +Q QQQQQ +L Sbjct: 864 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923 Query: 296 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 338 ++ + + +++ + +I ++ QL E R+ Sbjct: 924 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 966 Score = 37.7 bits (86), Expect = 0.046 Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Query: 213 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 272 E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R Sbjct: 724 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 779 Query: 273 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 332 ++E+L +KQ + ++Q ++ E ++A + + + RKQ +L Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839 Query: 333 MENSRQAVAK 342 + + AK Sbjct: 840 LRKQEEEAAK 849 Score = 35.4 bits (80), Expect = 0.23 Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%) Query: 175 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 234 +E LR E++K +L E ++++ +R+ + +E L +++++ + Q + Sbjct: 869 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 922 Query: 235 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 289 ++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ Sbjct: 923 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982 Query: 290 Q 290 Q Sbjct: 983 Q 983 Score = 32.3 bits (72), Expect = 1.9 Identities = 16/38 (42%), Positives = 23/38 (60%) Query: 257 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 E E K++ ER+ ++ +Q Q+ QQQQQQPP Q Sbjct: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1220 Score = 31.6 bits (70), Expect = 3.3 Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%) Query: 186 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 240 E K +KL E + E E R+ + EL +++ E++R Q ++ +A + Sbjct: 730 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 788 Query: 241 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 290 + E+++ +EE + + + +ERR ++E+ Q++L ++Q++ Sbjct: 789 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845 Score = 31.2 bits (69), Expect = 4.3 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 252 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 294 ++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q Sbjct: 1185 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1224 Score = 30.0 bits (66), Expect = 9.6 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 25/123 (20%) Query: 714 RKQRTLSMIE----EEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGK 769 + Q TLS+ E EE R Q REE+ ++QR+++++ Q + + L + G Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-------SGWGN 991 Query: 770 IEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVL 829 + K PS TT+ ++ EEA MQ + + H+ R R + S L Sbjct: 992 VSK----PSGTTKS---LLEIQQEEA-------RQMQKQQQQQQQHQQPNRARNNTHSNL 1037 Query: 830 EAT 832 + Sbjct: 1038 HTS 1040 >gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sapiens] Length = 1782 Score = 45.1 bits (105), Expect = 3e-04 Identities = 65/315 (20%), Positives = 117/315 (37%), Gaps = 67/315 (21%) Query: 530 DNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKA 589 + P + VSK S+ + ++ + D +E ++ + ++ + + EQV+ Sbjct: 870 EQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPL-EQVEAE 928 Query: 590 VSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDR 649 + + + E+ E EE EPP V+ P+ E R+ + +E Sbjct: 929 AALLTEEVLER---EVIAEE---------------EPPTVTEPLPENREARGDTVVSEAE 970 Query: 650 ALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLL---------ATQ 700 P+ + A + +GP+ EE G+ S E E+ S S L AT Sbjct: 971 LT-----PEAVTAAETAGPLGAEE----GTEASAAEETTEMVSAVSQLTDSPDTTEEATP 1021 Query: 701 ESDVMVGPFKLRSRKQRT---LSMIEEEI--------------------RAAQEREEE-- 735 +V G + +++RT L + E++ RA ER EE Sbjct: 1022 VQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQA 1081 Query: 736 ----LKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLA 791 LK++ V+ + K P + +T P EK P + + E L Sbjct: 1082 EASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKA-PQVTESIESSELVTTCQ 1140 Query: 792 PEEAAGTQRPKNLMQ 806 E AG + + +M+ Sbjct: 1141 AETLAGVKSQEMVME 1155 >gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sapiens] Length = 1684 Score = 45.1 bits (105), Expect = 3e-04 Identities = 65/315 (20%), Positives = 117/315 (37%), Gaps = 67/315 (21%) Query: 530 DNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKA 589 + P + VSK S+ + ++ + D +E ++ + ++ + + EQV+ Sbjct: 772 EQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPL-EQVEAE 830 Query: 590 VSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDR 649 + + + E+ E EE EPP V+ P+ E R+ + +E Sbjct: 831 AALLTEEVLER---EVIAEE---------------EPPTVTEPLPENREARGDTVVSEAE 872 Query: 650 ALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLL---------ATQ 700 P+ + A + +GP+ EE G+ S E E+ S S L AT Sbjct: 873 LT-----PEAVTAAETAGPLGAEE----GTEASAAEETTEMVSAVSQLTDSPDTTEEATP 923 Query: 701 ESDVMVGPFKLRSRKQRT---LSMIEEEI--------------------RAAQEREEE-- 735 +V G + +++RT L + E++ RA ER EE Sbjct: 924 VQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQA 983 Query: 736 ----LKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLA 791 LK++ V+ + K P + +T P EK P + + E L Sbjct: 984 EASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKA-PQVTESIESSELVTTCQ 1042 Query: 792 PEEAAGTQRPKNLMQ 806 E AG + + +M+ Sbjct: 1043 AETLAGVKSQEMVME 1057 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 45.1 bits (105), Expect = 3e-04 Identities = 104/510 (20%), Positives = 182/510 (35%), Gaps = 73/510 (14%) Query: 75 GTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHI---ELSNSSPDPMAEAERT 131 GT S +P G P P P S + PP E S +P ++E Sbjct: 88 GTGSADPERPP--GATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE 145 Query: 132 NGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPS 191 + H + + +Q+P+ P + +L+ L KE + + + + P+ Sbjct: 146 SDHDDAF-LSIMSPEIQLPLPPGKRRTQ---------SLSALPKER--DSSSEKDGRSPN 193 Query: 192 KLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK----WWNP--P 245 K +E+ IR RP + K R L+ + ++ +K WW P Sbjct: 194 K--------REKDHIR--RPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGP 243 Query: 246 QEKT----IEEQLDEEHLESHKKYK------ERKERRAQQEQLLLQKQLQQQQQQPPSQL 295 +EK + Q+ E H ++H +K ++ A+ L L ++ +++ S+ Sbjct: 244 KEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSET 303 Query: 296 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPF 355 TA A + ++ A + +++ D A E G + PR FS Sbjct: 304 GTAAAPGVS-SELLSVAAQTLLSS--DTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGV 360 Query: 356 YRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 415 + L D V GP SG + +PG P G G A+ G+ Sbjct: 361 HS-LDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAP---GEGGALAATGR- 415 Query: 416 GPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGL 475 P P++ + +ED R V+ + DD I D + ++ L +E Sbjct: 416 -PPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKE----- 469 Query: 476 DELSVRSQDTTVLETLSNDFS-MDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSE 534 V ++ S D S D + G + + + +S P P+ P + Sbjct: 470 ----------RVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPD 519 Query: 535 -----GRGEGVSKSFSDHGFYSPSSTLGDS 559 G+G G + S S S S++ S Sbjct: 520 PPVAFGKGYGSAPSSSASSPASSSASAATS 549 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 44.7 bits (104), Expect = 4e-04 Identities = 36/155 (23%), Positives = 71/155 (45%), Gaps = 30/155 (19%) Query: 186 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 245 E +K L ++E E+E+ + R EE+ E E+ER+E Sbjct: 2236 ELEKQESLSSEEEEEREE---EEEREEEEVREEEEERKE--------------------- 2271 Query: 246 QEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHER 305 +E+ E+Q+++E E KK KE+K+ Q+++ + +++ + ++ L S E Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL------SDEE 2325 Query: 306 ASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAV 340 + E+ V + + KQF+L E R+++ Sbjct: 2326 EEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSL 2360 Score = 33.5 bits (75), Expect = 0.87 Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 11/131 (8%) Query: 163 SRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKER 222 S + E L L+K+ E ++ + E++ E+E+ + E+ +E E+E Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286 Query: 223 RELIRSQAVKKNPGIAAKWWNPPQEKTIEEQ---LDEEHLESHKKYKERKERRAQQEQLL 279 ++ + + KK + K E+ EE+ + EE ES +E +E + +E++ Sbjct: 2287 KK--KKKKEKKKEEVQEK------EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVD 2338 Query: 280 LQKQLQQQQQQ 290 +K++ ++++Q Sbjct: 2339 REKEILKKEKQ 2349 Score = 32.3 bits (72), Expect = 1.9 Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 32/148 (21%) Query: 175 KEAKFELRAFH-EDKKPSKLFEDD-------EHEKEQYCIRKVRPSEEMLELEKERRELI 226 K+A E + H E +K K ++++ E EK K+ P EEML+ +K+ + Sbjct: 1461 KKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEE 1520 Query: 227 RSQAVKKNPGIAAK--WWNPPQEKTIEEQLDEE-------------HLES-------HKK 264 Q + +K + +E T+EE++ E H++ H+K Sbjct: 1521 WKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRK 1580 Query: 265 YKERKERRAQQEQLLLQKQ--LQQQQQQ 290 +++RAQ+E+ L Q++ L Q+++Q Sbjct: 1581 RARAEKKRAQEERKLAQEEEKLAQEERQ 1608 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 44.7 bits (104), Expect = 4e-04 Identities = 41/168 (24%), Positives = 81/168 (48%), Gaps = 9/168 (5%) Query: 175 KEAKFELRAFHEDKKPS---KLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV 231 ++AK E A + KK + K+ E + K++ R++R ++ E E+ +EL++ Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE-ERRHQELLQ---- 665 Query: 232 KKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER-RAQQEQLLLQKQLQQQQQQ 290 KK + + K + EQ ++E E ++ +ER+E+ R +QE+ ++QL +Q+++ Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725 Query: 291 PPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 338 + A ER + KE + E + +Q +L E Q Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773 Score = 35.8 bits (81), Expect = 0.17 Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 14/129 (10%) Query: 174 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE----LIRSQ 229 K+E + LR E K+ ++ E + E+E R+ + E E+ERRE L + Sbjct: 668 KEEEQERLRKAAEAKRLAEQREQERREQE----RREQERREQERREQERREQERQLAEQE 723 Query: 230 AVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 289 ++ + A+ +EK + Q ++ E +K K+ +++Q L ++QLQ++Q+ Sbjct: 724 RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK------EEQQRLAERQLQEEQE 777 Query: 290 QPPSQLCTA 298 + + A Sbjct: 778 KKAKEAAGA 786 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 44.7 bits (104), Expect = 4e-04 Identities = 41/168 (24%), Positives = 81/168 (48%), Gaps = 9/168 (5%) Query: 175 KEAKFELRAFHEDKKPS---KLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV 231 ++AK E A + KK + K+ E + K++ R++R ++ E E+ +EL++ Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE-ERRHQELLQ---- 661 Query: 232 KKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER-RAQQEQLLLQKQLQQQQQQ 290 KK + + K + EQ ++E E ++ +ER+E+ R +QE+ ++QL +Q+++ Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721 Query: 291 PPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 338 + A ER + KE + E + +Q +L E Q Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769 Score = 35.8 bits (81), Expect = 0.17 Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 14/129 (10%) Query: 174 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE----LIRSQ 229 K+E + LR E K+ ++ E + E+E R+ + E E+ERRE L + Sbjct: 664 KEEEQERLRKAAEAKRLAEQREQERREQE----RREQERREQERREQERREQERQLAEQE 719 Query: 230 AVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 289 ++ + A+ +EK + Q ++ E +K K+ +++Q L ++QLQ++Q+ Sbjct: 720 RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK------EEQQRLAERQLQEEQE 773 Query: 290 QPPSQLCTA 298 + + A Sbjct: 774 KKAKEAAGA 782 >gi|41406089 SRY-box 13 [Homo sapiens] Length = 622 Score = 44.7 bits (104), Expect = 4e-04 Identities = 71/318 (22%), Positives = 119/318 (37%), Gaps = 38/318 (11%) Query: 93 PVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVS 152 P HEA Q T P ++ P A+ S P G+ P Sbjct: 32 PCHEAPQGSATAAEPQPGDPARASQDSADPQAPAQGNFRGSWDCSSPE---GNGSPEPKR 88 Query: 153 PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPS 212 P + ++ S +F LK+ + D K L + K+ V+ + Sbjct: 89 PGVSEAASGSQEKLDFN-RNLKEVVPAIEKLLSSDWKERFLGRNSMEAKD------VKGT 141 Query: 213 EEML-ELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER 271 +E L E E + +I + ++ + A ++K + L E+ + + ++++E+ Sbjct: 142 QESLAEKELQLLVMIHQLSTLRDQLLTAH----SEQKNMAAMLFEKQQQQMELARQQQEQ 197 Query: 272 RAQQEQLLLQKQ-----LQQQQQQPPSQLCTAPA--SSHERASMIDKAKEDIVTEQIDFS 324 A+Q+Q L+Q+Q LQQQ QQ PA SH+ + ++ + + I Sbjct: 198 IAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCK 257 Query: 325 AARKQFQLMENSRQAVAKGQ------------STPRLFSIKPFYRPLGSVNSDKPLTN-- 370 QL+ + V K S P + KP L + +S L Sbjct: 258 PVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSS 317 Query: 371 --PRPPSVGGPPEDSGAS 386 PRPPS GGP D +S Sbjct: 318 CVPRPPSHGGPTRDLQSS 335 >gi|22758136 MAP7 domain containing 2 [Homo sapiens] Length = 732 Score = 44.7 bits (104), Expect = 4e-04 Identities = 56/273 (20%), Positives = 112/273 (41%), Gaps = 35/273 (12%) Query: 76 TSSPEPGAVV-----LVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAER 130 T P PG+ V + G P +A E + R+ + + + E Sbjct: 308 TKPPYPGSPVKYRLPALSGQDMPKRKA---EKEKSNKEREGTLAQQAAGPQGEEALEKHV 364 Query: 131 TNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKP 190 + H+ + A G + + T+ + + L +++A+ L+ E+++ Sbjct: 365 VDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQAR--LQKEQEEQER 422 Query: 191 SKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTI 250 + E D E+E+ K + EE L LE+E R+ + K Sbjct: 423 VEKEEQDRLEREEL---KRKAEEERLRLEEEARK------------------QEEERKRQ 461 Query: 251 EEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQP--PSQLCTAPASSHERASM 308 EE+ ++ E +K E +R+A++E LL +KQ Q++Q++ Q A + E A Sbjct: 462 EEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQ 521 Query: 309 IDKAKEDIV--TEQIDFSAARKQFQLMENSRQA 339 + +E I+ EQ ++ ++M+ +R++ Sbjct: 522 MRLEREQIMLQIEQERLERKKRIDEIMKRTRKS 554 Score = 39.3 bits (90), Expect = 0.016 Identities = 116/599 (19%), Positives = 207/599 (34%), Gaps = 119/599 (19%) Query: 212 SEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER 271 S+E L KERRE + I K +K Q +++ E +K +E+++R Sbjct: 51 SDERQRLAKERREEREKCLAAREQQILEK------QKRARLQYEKQMEERWRKLEEQRQR 104 Query: 272 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAK------------------ 313 Q+ + +K+ Q+ +++ +L S ER ++ K Sbjct: 105 EDQKRAAVEEKRKQKLREEE-ERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDAC 163 Query: 314 EDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRP 373 + + T + + S VA S R+F + P PLG +N Sbjct: 164 DKLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLN---------- 213 Query: 374 PSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAE 433 P + +K + S AG G A G E E KRG + Sbjct: 214 ------PSYKSSPTRNIEKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTA---- 263 Query: 434 DGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSN 493 TS V + L + E G+ + R + +T + Sbjct: 264 ----TSLPVV-----------------NFGSPLRRCEFSGGIPK---RPSSPVISKTATK 299 Query: 494 DFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPS 553 + S +TT S + LP D P + E + G + Sbjct: 300 AYPQ--------SPKTTKPPYPGSPVKYRLPALSGQDMPKR-KAEKEKSNKEREGTLAQQ 350 Query: 554 STLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEA-TVEEAEA 612 + P ++ LE ++ + + +E+ A + + A P A T + EA Sbjct: 351 AA---GPQGEEALE-------KHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEA 400 Query: 613 AAFGSEK------PQSMFEPPQVSSPVQEK--RDVLPKILPAEDRALRERGPPQPLPAVQ 664 A +EK + E +V Q++ R+ L + E L E Q + Sbjct: 401 AKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQE----E 456 Query: 665 PSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEE 724 E+ + EG K E A+ ++ LL ++ + ++++ +MIE+ Sbjct: 457 ERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQE----------QEKQEKAMIEK 506 Query: 725 EIRAAQEREEE------LKRQRQVLQSTQS--PRTKNAPSLPSRTCYKTAPGKIEKVKP 775 + AA+ + E L+R++ +LQ Q R K + RT P +++K P Sbjct: 507 QKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDP 565 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 44.3 bits (103), Expect = 5e-04 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 1/71 (1%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQK-SPGALETPSAAGSQGNTASQGKEG 416 P G+ P PP + GPP +SG A G + SPG +P A G +G T G G Sbjct: 987 PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046 Query: 417 PYSEPSKRGPL 427 P GP+ Sbjct: 1047 APGAPGAPGPV 1057 Score = 39.3 bits (90), Expect = 0.016 Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 4/71 (5%) Query: 360 GSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSP----GALETPSAAGSQGNTASQGKE 415 G V P N PP GP G +G+ P G + P G G S G + Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940 Query: 416 GPYSEPSKRGP 426 GP P GP Sbjct: 941 GPAGAPGTPGP 951 Score = 37.4 bits (85), Expect = 0.060 Identities = 21/53 (39%), Positives = 23/53 (43%), Gaps = 2/53 (3%) Query: 373 PPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRG 425 P GGPP G S G +PG+ A G G QG GP E KRG Sbjct: 420 PQGPGGPPGPKGNSGEPG--APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRG 470 Score = 36.6 bits (83), Expect = 0.10 Identities = 23/72 (31%), Positives = 26/72 (36%), Gaps = 1/72 (1%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKS-PGALETPSAAGSQGNTASQGKEG 416 P GS P P GPP +GA G PG + P G G+ G G Sbjct: 1122 PPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG 1181 Query: 417 PYSEPSKRGPLS 428 P P GP S Sbjct: 1182 PPGPPGPPGPPS 1193 Score = 36.2 bits (82), Expect = 0.13 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Query: 370 NPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGP 426 N GPP +G + G PGA+ AG QG S+G +G EP GP Sbjct: 324 NDGATGAAGPPGPTGPAGPPG--FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378 Score = 35.4 bits (80), Expect = 0.23 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 7/60 (11%) Query: 374 PSVGGPPEDSGASAAKGQKSPGALE-------TPSAAGSQGNTASQGKEGPYSEPSKRGP 426 P + G P GA G + PG P A GS+G+T ++G+ GP GP Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGP 462 Score = 35.4 bits (80), Expect = 0.23 Identities = 22/69 (31%), Positives = 26/69 (37%), Gaps = 1/69 (1%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQK-SPGALETPSAAGSQGNTASQGKEG 416 P G S P P G P ++G AKG SPG+ G G G+ G Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG 566 Query: 417 PYSEPSKRG 425 P P RG Sbjct: 567 PPGPPGARG 575 Score = 35.4 bits (80), Expect = 0.23 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 8/75 (10%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGP 417 P G+ + P PP GP +G A GQ PGA P AG++G+ G GP Sbjct: 792 PTGARGAPGDRGEPGPP---GPAGFAGPPGADGQ--PGAKGEPGDAGAKGDAGPPGPAGP 846 Query: 418 YSEPSKRGPLSKLWA 432 P GP+ + A Sbjct: 847 AGPP---GPIGNVGA 858 Score = 35.4 bits (80), Expect = 0.23 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 371 PRPPSVGGPPEDSGASAAKGQKSP-GALETPSAAGSQGNTASQGKEGPYSEPSKRG 425 P P G P G S A G++ P G + P AG G + +G G P + G Sbjct: 973 PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDG 1028 Score = 35.0 bits (79), Expect = 0.30 Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 9/87 (10%) Query: 341 AKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQK-SPGALET 399 AKG++ P+ P GS P PP G +G A GQ + GA Sbjct: 351 AKGEAGPQ--------GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402 Query: 400 PSAAGSQGNTASQGKEGPYSEPSKRGP 426 P AG+ G ++G GP GP Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGP 429 Score = 35.0 bits (79), Expect = 0.30 Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 7/62 (11%) Query: 371 PRPPSVGGPPE---DSGASAAKGQKS----PGALETPSAAGSQGNTASQGKEGPYSEPSK 423 P P GPP + GA AKG + PGA P AAG G G GP P Sbjct: 841 PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP 900 Query: 424 RG 425 G Sbjct: 901 AG 902 Score = 34.7 bits (78), Expect = 0.39 Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 2/53 (3%) Query: 374 PSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGP 426 P GPP ++G +G PG L P +G++G G+ G P GP Sbjct: 646 PGPAGPPGEAGKPGEQGV--PGDLGAPGPSGARGERGFPGERGVQGPPGPAGP 696 Score = 34.3 bits (77), Expect = 0.51 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 4/69 (5%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSP-GALETPSAAGSQGNTASQGKEG 416 P G P N P G P G + AKG+ P G P AG +G ++G+ G Sbjct: 420 PQGPGGPPGPKGNSGEP---GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG 476 Query: 417 PYSEPSKRG 425 P P G Sbjct: 477 PTGLPGPPG 485 Score = 34.3 bits (77), Expect = 0.51 Identities = 20/68 (29%), Positives = 25/68 (36%), Gaps = 2/68 (2%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGP 417 P G P P + GPP + G ++G PGA G G S G GP Sbjct: 462 PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG--FPGADGVAGPKGPAGERGSPGPAGP 519 Query: 418 YSEPSKRG 425 P + G Sbjct: 520 KGSPGEAG 527 Score = 33.9 bits (76), Expect = 0.66 Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 5/69 (7%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGP 417 P G P P P GPP + G A G P P G G+ GK G Sbjct: 183 PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRG--PPGPPGKNGDDGEAGKPG- 239 Query: 418 YSEPSKRGP 426 P +RGP Sbjct: 240 --RPGERGP 246 Score = 33.5 bits (75), Expect = 0.87 Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 6/77 (7%) Query: 360 GSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYS 419 GS D P P G P G A+GQ G + P G+ G G+ G Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ--AGVMGFPGPKGAAGEPGKAGERGVPG 602 Query: 420 EPSKRGPLSKLWAEDGE 436 P GP K DGE Sbjct: 603 PPGAVGPAGK----DGE 615 Score = 32.7 bits (73), Expect = 1.5 Identities = 21/74 (28%), Positives = 25/74 (33%), Gaps = 7/74 (9%) Query: 360 GSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKS-------PGALETPSAAGSQGNTASQ 412 GS +D P P P G G GQ+ PG P G G + + Sbjct: 935 GSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGER 994 Query: 413 GKEGPYSEPSKRGP 426 G GP P GP Sbjct: 995 GPPGPMGPPGLAGP 1008 Score = 32.3 bits (72), Expect = 1.9 Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 10/66 (15%) Query: 371 PRPPSVGGPPEDSGASAAKGQKS-PGALETPSAAGSQGNTASQG---------KEGPYSE 420 P P V GPP +G +G + PG P G +G S+G +GP E Sbjct: 451 PGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE 510 Query: 421 PSKRGP 426 GP Sbjct: 511 RGSPGP 516 Score = 32.0 bits (71), Expect = 2.5 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 8/49 (16%) Query: 378 GPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGP 426 GPP +GA KG+ P +G G T ++G G EP GP Sbjct: 770 GPPGPAGAPGDKGESGP--------SGPAGPTGARGAPGDRGEPGPPGP 810 Score = 31.6 bits (70), Expect = 3.3 Identities = 25/79 (31%), Positives = 28/79 (35%), Gaps = 13/79 (16%) Query: 360 GSVNSD--KPLTNP-RPPSVGGPPEDSGASAAKGQKSP----------GALETPSAAGSQ 406 GS D + LT P PP G P D G S G P G P AG Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA 814 Query: 407 GNTASQGKEGPYSEPSKRG 425 G + G+ G EP G Sbjct: 815 GPPGADGQPGAKGEPGDAG 833 Score = 31.2 bits (69), Expect = 4.3 Identities = 21/69 (30%), Positives = 22/69 (31%), Gaps = 1/69 (1%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKS-PGALETPSAAGSQGNTASQGKEG 416 P G D P P GPP GA G PG +G G G G Sbjct: 225 PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG 284 Query: 417 PYSEPSKRG 425 P EP G Sbjct: 285 PKGEPGSPG 293 Score = 31.2 bits (69), Expect = 4.3 Identities = 20/76 (26%), Positives = 28/76 (36%), Gaps = 4/76 (5%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALE----TPSAAGSQGNTASQG 413 P+G V + P P G + G KG + L+ P + G QG + + G Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG 1136 Query: 414 KEGPYSEPSKRGPLSK 429 GP P G K Sbjct: 1137 PAGPRGPPGSAGAPGK 1152 Score = 30.8 bits (68), Expect = 5.6 Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 2/68 (2%) Query: 359 LGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPY 418 +G D PP GP + G G SPG P AG G G++G Sbjct: 607 VGPAGKDGEAGAQGPPGPAGPAGERGEQGPAG--SPGFQGLPGPAGPPGEAGKPGEQGVP 664 Query: 419 SEPSKRGP 426 + GP Sbjct: 665 GDLGAPGP 672 Score = 30.8 bits (68), Expect = 5.6 Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 7/61 (11%) Query: 373 PPSVGGPPEDSGASAAKGQK-------SPGALETPSAAGSQGNTASQGKEGPYSEPSKRG 425 PP GP +GA G K +PG+ P G G + G GP + G Sbjct: 690 PPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG 749 Query: 426 P 426 P Sbjct: 750 P 750 Score = 30.4 bits (67), Expect = 7.3 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 4/58 (6%) Query: 373 PPSVGGPPEDSGASAAKGQKS-PGALETPSA---AGSQGNTASQGKEGPYSEPSKRGP 426 P G P ++GA G + PG P A AG++GN + G GP GP Sbjct: 285 PKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGP 342 Score = 30.4 bits (67), Expect = 7.3 Identities = 20/69 (28%), Positives = 24/69 (34%), Gaps = 1/69 (1%) Query: 358 PLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSP-GALETPSAAGSQGNTASQGKEG 416 P G P P GPP G + G P GA P AG +G G G Sbjct: 549 PDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVG 608 Query: 417 PYSEPSKRG 425 P + + G Sbjct: 609 PAGKDGEAG 617 Score = 30.0 bits (66), Expect = 9.6 Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 390 GQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRG 425 G +SP ET G +G+T +G GP P + G Sbjct: 98 GSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDG 133 Score = 30.0 bits (66), Expect = 9.6 Identities = 18/55 (32%), Positives = 22/55 (40%), Gaps = 5/55 (9%) Query: 371 PRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRG 425 P P G P +G G PGA+ AG G +QG GP +RG Sbjct: 583 PGPKGAAGEPGKAGERGVPGP--PGAV---GPAGKDGEAGAQGPPGPAGPAGERG 632 >gi|48255900 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform a [Homo sapiens] Length = 1590 Score = 43.9 bits (102), Expect = 6e-04 Identities = 44/200 (22%), Positives = 80/200 (40%), Gaps = 26/200 (13%) Query: 602 GPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGP---PQ 658 GP + + + + S P + P VSSP+ P++ P++ AL P Q Sbjct: 107 GPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQ 166 Query: 659 PLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRT 718 P P P+ + + R + + + L T +L + +RT Sbjct: 167 PNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPET---------------LQLAVQGKRT 211 Query: 719 LSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPP-P 777 L +++ Q+++++ ++Q+Q Q Q + + P P +T + P + +P P Sbjct: 212 LPGLQQ-----QQQQQQQQQQQQQQQQQQQQQPQQQPPQP-QTQQQQQPALVNYNRPSGP 265 Query: 778 SPTTEGPSLQPDLAPEEAAG 797 P GPS P P A G Sbjct: 266 GPELSGPS-TPQKLPVPAPG 284 Score = 31.2 bits (69), Expect = 4.3 Identities = 28/129 (21%), Positives = 51/129 (39%), Gaps = 32/129 (24%) Query: 268 RKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAAR 327 +++++ QQ+Q Q+Q QQQQQQP Q ++ ++++ + ++ Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPEL------ 269 Query: 328 KQFQLMENSRQAVAKGQSTPRLFSI-KPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGAS 386 G STP+ + P RP +P PP+ PP + Sbjct: 270 --------------SGPSTPQKLPVPAPGGRP-----------SPAPPAAAQPPAAAVPG 304 Query: 387 AAKGQKSPG 395 + Q +PG Sbjct: 305 PSVPQPAPG 313 Score = 30.4 bits (67), Expect = 7.3 Identities = 14/48 (29%), Positives = 29/48 (60%) Query: 245 PQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPP 292 P +T++ + + + +++++++ QQ+Q Q+Q QQ QQQPP Sbjct: 197 PLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPP 244 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.124 0.347 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,154,242 Number of Sequences: 37866 Number of extensions: 2103791 Number of successful extensions: 23497 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 213 Number of HSP's successfully gapped in prelim test: 772 Number of HSP's that attempted gapping in prelim test: 13878 Number of HSP's gapped (non-prelim): 7561 length of query: 859 length of database: 18,247,518 effective HSP length: 111 effective length of query: 748 effective length of database: 14,044,392 effective search space: 10505205216 effective search space used: 10505205216 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.