Search of human proteins with 21071028

Search of human proteins with 21071028

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
         (131 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]          259   3e-70
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   232   7e-62
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]           195   1e-50
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   187   3e-48
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...   170   3e-43
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...   143   3e-35
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...   143   3e-35
gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]          143   3e-35
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   119   7e-28
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    89   7e-19
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  48   3e-06
gi|66472382 nischarin [Homo sapiens]                                   47   6e-06
gi|21361633 leucine rich repeat containing 40 [Homo sapiens]           45   1e-05
gi|167555127 CD180 molecule [Homo sapiens]                             44   4e-05
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo...    43   8e-05
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap...    42   2e-04
gi|59823631 G protein-coupled receptor 125 [Homo sapiens]              39   9e-04
gi|55743114 leucine rich repeat containing 49 [Homo sapiens]           39   0.001
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s...    39   0.002
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s...    39   0.002
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s...    39   0.002
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s...    39   0.002
gi|95113664 leucine rich repeat containing 1 [Homo sapiens]            39   0.002
gi|218931217 leucine rich repeat containing 61 [Homo sapiens]          38   0.003
gi|13027616 leucine rich repeat containing 61 [Homo sapiens]           38   0.003
gi|117414162 sodium channel associated protein 2 isoform a [Homo...    38   0.003
gi|31377705 centrosomal protein 97kDa [Homo sapiens]                   38   0.003
gi|238908508 leucine-rich repeat and death domain-containing pro...    37   0.004
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    37   0.006
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    37   0.006

>gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
          Length = 131

 Score =  259 bits (663), Expect = 3e-70
 Identities = 131/131 (100%), Positives = 131/131 (100%)

Query: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60
           MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL
Sbjct: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60

Query: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
           PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL
Sbjct: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120

Query: 121 FTCEVTNLNNY 131
           FTCEVTNLNNY
Sbjct: 121 FTCEVTNLNNY 131


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score =  232 bits (591), Expect = 7e-62
 Identities = 117/131 (89%), Positives = 123/131 (93%)

Query: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60
           MEMG+ IHLELRNRTPSDVKEL LDNS+SNEGKLEGLTDEFEELE L+TIN+GLTSIANL
Sbjct: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60

Query: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
           PKLNKLKKLELS NR S GLEVLAEKCPNL HLNLSGNKIKDLSTIEPLKKLENL+SLDL
Sbjct: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120

Query: 121 FTCEVTNLNNY 131
           F CEVTNLN+Y
Sbjct: 121 FNCEVTNLNDY 131


>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
          Length = 234

 Score =  195 bits (495), Expect = 1e-50
 Identities = 105/131 (80%), Positives = 114/131 (87%), Gaps = 4/131 (3%)

Query: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60
           MEMG+ IH ELRNR PSDVKEL LDNS+SNEGKLE LTDEFEELE L+ IN GLTSI++L
Sbjct: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60

Query: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
           PKL KL+KLEL   R S GLEVLAEKCPNL HL LSGNKIKDLSTIEPLK+LENL+SLDL
Sbjct: 61  PKL-KLRKLEL---RVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116

Query: 121 FTCEVTNLNNY 131
           F CEVTNLN+Y
Sbjct: 117 FNCEVTNLNDY 127


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score =  187 bits (474), Expect = 3e-48
 Identities = 93/131 (70%), Positives = 111/131 (84%)

Query: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60
           M+M + IHLELRNRTP+ V+EL LDN +SN+GK+EGLT EF  LE L+ IN+GL S++NL
Sbjct: 1   MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 60

Query: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
           PKL KLKKLELS NR   GL++LAEK PNL HLNLSGNK+KD+ST+EPLKKLE L+SLDL
Sbjct: 61  PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 120

Query: 121 FTCEVTNLNNY 131
           F CEVTNLN+Y
Sbjct: 121 FNCEVTNLNDY 131


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score =  170 bits (430), Expect = 3e-43
 Identities = 86/131 (65%), Positives = 104/131 (79%)

Query: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60
           MEM K I+LELRNR+P +V EL LDN     G++EGL D F+ELE L+  N+ L+S+A L
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
           P LNKL+KLELS N  S GLEVLAEKCPNL +LNLSGNKIKDLST+E L+ L+NL+SLDL
Sbjct: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120

Query: 121 FTCEVTNLNNY 131
           F CE+TNL +Y
Sbjct: 121 FNCEITNLEDY 131


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  143 bits (361), Expect = 3e-35
 Identities = 74/113 (65%), Positives = 86/113 (76%)

Query: 19  VKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV 78
           V+E  LDN +SN+ K+E LT EF  LE L  IN+GL SI+NLPKL KLKK  LS NR   
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 79  GLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNNY 131
           GL + AEK PNL HLNLSG K+KD+ST+EPLKKLE L+SLDLF CEV NLN+Y
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDY 151


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  143 bits (361), Expect = 3e-35
 Identities = 74/113 (65%), Positives = 86/113 (76%)

Query: 19  VKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV 78
           V+E  LDN +SN+ K+E LT EF  LE L  IN+GL SI+NLPKL KLKK  LS NR   
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 79  GLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNNY 131
           GL + AEK PNL HLNLSG K+KD+ST+EPLKKLE L+SLDLF CEV NLN+Y
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDY 151


>gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]
          Length = 450

 Score =  143 bits (361), Expect = 3e-35
 Identities = 74/113 (65%), Positives = 86/113 (76%)

Query: 19  VKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV 78
           V+E  LDN +SN+ K+E LT EF  LE L  IN+GL SI+NLPKL KLKK  LS NR   
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 79  GLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNNY 131
           GL + AEK PNL HLNLSG K+KD+ST+EPLKKLE L+SLDLF CEV NLN+Y
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDY 151


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score =  119 bits (298), Expect = 7e-28
 Identities = 58/81 (71%), Positives = 69/81 (85%)

Query: 51  NIGLTSIANLPKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLK 110
           N+ L+S+A LP LNKL+KLELS N  S GLEVLAEKCPNL +LNLSGNKIKDLST+E L+
Sbjct: 3   NVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQ 62

Query: 111 KLENLESLDLFTCEVTNLNNY 131
            L+NL+SLDLF CE+TNL +Y
Sbjct: 63  NLKNLKSLDLFNCEITNLEDY 83


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 89.4 bits (220), Expect = 7e-19
 Identities = 53/131 (40%), Positives = 69/131 (52%), Gaps = 41/131 (31%)

Query: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60
           MEM K I+LELRNR+P +V EL LDN     G++EGL D F+ELE L+  N+ L+S+A L
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
           P LNKL+K                                         + L+NL+SLDL
Sbjct: 61  PSLNKLRK-----------------------------------------QNLKNLKSLDL 79

Query: 121 FTCEVTNLNNY 131
           F CE+TNL +Y
Sbjct: 80  FNCEITNLEDY 90


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 47.8 bits (112), Expect = 3e-06
 Identities = 40/113 (35%), Positives = 56/113 (49%), Gaps = 1/113 (0%)

Query: 19  VKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV 78
           VK   L+ S +  GK+E L D+  +L  LN     ++ I  +  +  L+KL L+ N    
Sbjct: 125 VKLEVLNLSYNLIGKIEKL-DKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEH 183

Query: 79  GLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNNY 131
               L +K  +L  LNL GNKI  L  I  LK L++L SL L    V  L +Y
Sbjct: 184 IPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHY 236


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 46.6 bits (109), Expect = 6e-06
 Identities = 33/96 (34%), Positives = 51/96 (53%), Gaps = 1/96 (1%)

Query: 24  LDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVL 83
           LD S ++  +++       ++E L+  + GL  + NL  L  L  L+LS N+ S  LE L
Sbjct: 292 LDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLS-SLEGL 350

Query: 84  AEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLD 119
             K  N+  LNL+GN ++ LS +  L  L NL+  D
Sbjct: 351 HTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRD 386



 Score = 33.5 bits (75), Expect = 0.049
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 24  LDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVL 83
           LD S +    LEGL  +   ++ LN     L S++ L KL  L  L+L  NR     EV 
Sbjct: 337 LDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVR 396

Query: 84  A-EKCPNLIHLNLSGNKI 100
           +    P L H++L  N +
Sbjct: 397 SIGSLPCLEHVSLLNNPL 414


>gi|21361633 leucine rich repeat containing 40 [Homo sapiens]
          Length = 602

 Score = 45.4 bits (106), Expect = 1e-05
 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 14/117 (11%)

Query: 17  SDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLP----KLNKLKKLELS 72
           +D+ +L + N+     KL+ LTD+   L  L  ++I    + +LP    +L  L+KL +S
Sbjct: 82  TDLTKLIISNN-----KLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVS 136

Query: 73  SNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTI-EPLKKLENLESLDLFTCEVTNL 128
            N+    L++L E+  NL +L     +  +L+ I E  ++L NLE LDL    +T +
Sbjct: 137 HNK----LKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 189



 Score = 27.3 bits (59), Expect = 3.5
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 8/90 (8%)

Query: 34  LEGLTDEFEELELLNTINIGLTSIANLP----KLNKLKKLELSSNRASVGLEVLAEKCPN 89
           L  L +E E L  L TIN+       LP    ++  L+ + +S+N+         +   N
Sbjct: 484 LNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMEN 543

Query: 90  LIHLNLSGNKIKDLSTIEP-LKKLENLESL 118
           L  L+L  N   DL  I P L    NL +L
Sbjct: 544 LTTLDLQNN---DLLQIPPELGNCVNLRTL 570


>gi|167555127 CD180 molecule [Homo sapiens]
          Length = 661

 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%)

Query: 40  EFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNK 99
           + +EL+L  T   GL S   +  LN LKKL LS N      ++ A   P+L HL + GN 
Sbjct: 299 QLQELDLTATHLKGLPS--GMKGLNLLKKLVLSVNHFDQLCQISAANFPSLTHLYIRGNV 356

Query: 100 IKDLSTIEPLKKLENLESLDL 120
            K    +  L+KL NL++LDL
Sbjct: 357 KKLHLGVGCLEKLGNLQTLDL 377



 Score = 30.0 bits (66), Expect = 0.54
 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 13/126 (10%)

Query: 8   HLELRNRTPSDVKELFLD-NSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKL 66
           HL +R     +VK+L L        G L+ L     ++E  +  ++ L ++++L  LN  
Sbjct: 349 HLYIRG----NVKKLHLGVGCLEKLGNLQTLDLSHNDIEASDCCSLQLKNLSHLQTLNL- 403

Query: 67  KKLELSSNRASVGLEVLAEK-CPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEV 125
                 S+   +GL+  A K CP L  L+L+  ++   +   P + L  L+ L+L  C +
Sbjct: 404 ------SHNEPLGLQSQAFKECPQLELLDLAFTRLHINAPQSPFQNLHFLQVLNLTYCFL 457

Query: 126 TNLNNY 131
              N +
Sbjct: 458 DTSNQH 463



 Score = 28.5 bits (62), Expect = 1.6
 Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 41  FEELELLNTINIGLTSI-ANLPK-----LNKLKKLELSSNRASVGLEVLAEKCPNLIHLN 94
           F+E   L  +++  T +  N P+     L+ L+ L L+        + L    P L HLN
Sbjct: 416 FKECPQLELLDLAFTRLHINAPQSPFQNLHFLQVLNLTYCFLDTSNQHLLAGLPVLRHLN 475

Query: 95  LSGNKIKD--LSTIEPLKKLENLESLDLFTCEVTNLN 129
           L GN  +D  ++    L+ + +LE L L +C + +++
Sbjct: 476 LKGNHFQDGTITKTNLLQTVGSLEVLILSSCGLLSID 512


>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
           sapiens]
          Length = 255

 Score = 42.7 bits (99), Expect = 8e-05
 Identities = 26/98 (26%), Positives = 49/98 (50%)

Query: 34  LEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVLAEKCPNLIHL 93
           +E L    ++ + ++  +  +  +   P L +LK L +++NR     E L +  P L  L
Sbjct: 34  IENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPCLTEL 93

Query: 94  NLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNNY 131
            L+ N + +L  ++PL  L++L  L +    VTN  +Y
Sbjct: 94  ILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHY 131


>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
           sapiens]
          Length = 360

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 43/113 (38%), Positives = 59/113 (52%), Gaps = 10/113 (8%)

Query: 19  VKELFL-DNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRAS 77
           ++EL L DN       LE LT    ELE+L+     L +I  + KL +LKKL L +N+ S
Sbjct: 122 LRELDLYDNQIKKIENLEALT----ELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKIS 177

Query: 78  VGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNN 130
             +E L+     L  L L  N+I+    IE +  L NLESL L   ++T L N
Sbjct: 178 -KIENLS-NLHQLQMLELGSNRIR---AIENIDTLTNLESLFLGKNKITKLQN 225



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 3/107 (2%)

Query: 24  LDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVL 83
           LD S +    +EG+ D+   L+ L  +N  ++ I NL  L++L+ LEL SNR      + 
Sbjct: 147 LDISFNLLRNIEGV-DKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENI- 204

Query: 84  AEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNN 130
            +   NL  L L  NKI  L  ++ L  L  L        ++  L N
Sbjct: 205 -DTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQN 250



 Score = 32.7 bits (73), Expect = 0.083
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 16/100 (16%)

Query: 28  QSNE-GKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVLAEK 86
           QSN   K+EGL +     EL  + N G+  I  L   NKL  L+++SNR         +K
Sbjct: 238 QSNRLTKIEGLQNLVNLRELYLSHN-GIEVIEGLENNNKLTMLDIASNR--------IKK 288

Query: 87  CPNLIHLN------LSGNKIKDLSTIEPLKKLENLESLDL 120
             N+ HL       ++ N ++  S ++ LK   +LE++ L
Sbjct: 289 IENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYL 328


>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
          Length = 1321

 Score = 39.3 bits (90), Expect = 9e-04
 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 11/108 (10%)

Query: 16  PSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPK-----LNKLKKLE 70
           P+    L L N++ +E K       F  L LL  +++    I+++       L+ LK+L+
Sbjct: 80  PNRTVTLILSNNKISELK----NGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRLD 135

Query: 71  LSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLS--TIEPLKKLENLE 116
           L++NR       +     NL+ LNLSGN    LS  T + L  L +LE
Sbjct: 136 LTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLE 183


>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
          Length = 686

 Score = 38.9 bits (89), Expect = 0.001
 Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 7/116 (6%)

Query: 17  SDVKELFLDNSQSNEGKLE--GLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSN 74
           S+ K L+ D       KL    + +  + L LLN  +  +T I N+  L KL  L+L  N
Sbjct: 85  SEEKILYSDRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDN 144

Query: 75  RASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNN 130
           +      +   +C  +  L L  N+IK +S +E LK   +L+ LDL   ++T + N
Sbjct: 145 QIEEISGLSTLRCLRV--LLLGKNRIKKISNLENLK---SLDVLDLHGNQITKIEN 195


>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 11/100 (11%)

Query: 33  KLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSN--RASVGLEVLAEKCPNL 90
           K EG+   F+++  L      +  I NL +   L+KL+L +N      GLE LA    +L
Sbjct: 36  KQEGIL--FKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLA----HL 89

Query: 91  IHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNN 130
           + L+LS N I+   TIE L  L NLE L LF   ++ +++
Sbjct: 90  VWLDLSFNNIE---TIEGLDTLVNLEDLSLFNNRISKIDS 126



 Score = 31.6 bits (70), Expect = 0.19
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 40  EFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV--GLEVLAEKCPNLIHLNLSG 97
           +FE L  L   N  +  I  L  L  L  L+LS N      GL+ L     NL  L+L  
Sbjct: 63  QFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLV----NLEDLSLFN 118

Query: 98  NKIKDLSTIEPLKKLENL 115
           N+I  + +++ L KL+ L
Sbjct: 119 NRISKIDSLDALVKLQVL 136


>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 11/100 (11%)

Query: 33  KLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSN--RASVGLEVLAEKCPNL 90
           K EG+   F+++  L      +  I NL +   L+KL+L +N      GLE LA    +L
Sbjct: 36  KQEGIL--FKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLA----HL 89

Query: 91  IHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNN 130
           + L+LS N I+   TIE L  L NLE L LF   ++ +++
Sbjct: 90  VWLDLSFNNIE---TIEGLDTLVNLEDLSLFNNRISKIDS 126



 Score = 31.6 bits (70), Expect = 0.19
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 40  EFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV--GLEVLAEKCPNLIHLNLSG 97
           +FE L  L   N  +  I  L  L  L  L+LS N      GL+ L     NL  L+L  
Sbjct: 63  QFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLV----NLEDLSLFN 118

Query: 98  NKIKDLSTIEPLKKLENL 115
           N+I  + +++ L KL+ L
Sbjct: 119 NRISKIDSLDALVKLQVL 136


>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 11/100 (11%)

Query: 33  KLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSN--RASVGLEVLAEKCPNL 90
           K EG+   F+++  L      +  I NL +   L+KL+L +N      GLE LA    +L
Sbjct: 36  KQEGIL--FKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLA----HL 89

Query: 91  IHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNN 130
           + L+LS N I+   TIE L  L NLE L LF   ++ +++
Sbjct: 90  VWLDLSFNNIE---TIEGLDTLVNLEDLSLFNNRISKIDS 126



 Score = 31.6 bits (70), Expect = 0.19
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 40  EFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV--GLEVLAEKCPNLIHLNLSG 97
           +FE L  L   N  +  I  L  L  L  L+LS N      GL+ L     NL  L+L  
Sbjct: 63  QFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLV----NLEDLSLFN 118

Query: 98  NKIKDLSTIEPLKKLENL 115
           N+I  + +++ L KL+ L
Sbjct: 119 NRISKIDSLDALVKLQVL 136


>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 11/100 (11%)

Query: 33  KLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSN--RASVGLEVLAEKCPNL 90
           K EG+   F+++  L      +  I NL +   L+KL+L +N      GLE LA    +L
Sbjct: 36  KQEGIL--FKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLA----HL 89

Query: 91  IHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNN 130
           + L+LS N I+   TIE L  L NLE L LF   ++ +++
Sbjct: 90  VWLDLSFNNIE---TIEGLDTLVNLEDLSLFNNRISKIDS 126



 Score = 31.6 bits (70), Expect = 0.19
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 40  EFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASV--GLEVLAEKCPNLIHLNLSG 97
           +FE L  L   N  +  I  L  L  L  L+LS N      GL+ L     NL  L+L  
Sbjct: 63  QFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLV----NLEDLSLFN 118

Query: 98  NKIKDLSTIEPLKKLENL 115
           N+I  + +++ L KL+ L
Sbjct: 119 NRISKIDSLDALVKLQVL 136


>gi|95113664 leucine rich repeat containing 1 [Homo sapiens]
          Length = 524

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 37/108 (34%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 11  LRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLE 70
           L+N    DV E  L+        L  LTD      LL TI  G      + KL KL  L+
Sbjct: 219 LKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDG------IGKLKKLSILK 272

Query: 71  LSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDL-STIEPLKKLENLES 117
           +  NR +   E + E C +L  L L+ N++  L  +I  LKKL NL +
Sbjct: 273 VDQNRLTQLPEAVGE-CESLTELVLTENQLLTLPKSIGKLKKLSNLNA 319


>gi|218931217 leucine rich repeat containing 61 [Homo sapiens]
          Length = 259

 Score = 37.7 bits (86), Expect = 0.003
 Identities = 32/85 (37%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 36  GLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNL 95
           G   E   LE L+     LT +  L  L +L  L +S+NR + GLE LA  C NL  LN 
Sbjct: 47  GCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLT-GLEPLAT-CENLQSLNA 104

Query: 96  SGNKIKDLSTIEPLKKLENLESLDL 120
           +GN +     ++ L  L  LE L L
Sbjct: 105 AGNLLATPGQLQCLAGLPCLEYLRL 129


>gi|13027616 leucine rich repeat containing 61 [Homo sapiens]
          Length = 259

 Score = 37.7 bits (86), Expect = 0.003
 Identities = 32/85 (37%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 36  GLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNL 95
           G   E   LE L+     LT +  L  L +L  L +S+NR + GLE LA  C NL  LN 
Sbjct: 47  GCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLT-GLEPLAT-CENLQSLNA 104

Query: 96  SGNKIKDLSTIEPLKKLENLESLDL 120
           +GN +     ++ L  L  LE L L
Sbjct: 105 AGNLLATPGQLQCLAGLPCLEYLRL 129


>gi|117414162 sodium channel associated protein 2 isoform a [Homo
           sapiens]
          Length = 1032

 Score = 37.7 bits (86), Expect = 0.003
 Identities = 38/122 (31%), Positives = 62/122 (50%), Gaps = 15/122 (12%)

Query: 19  VKELFLDNSQ-------SNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLEL 71
           + EL LD++        +N  K+E + D    L+ L+  +  ++ I  L  L KL  L L
Sbjct: 36  ISELSLDSTLHAVNLHCNNISKIEAI-DHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNL 94

Query: 72  SSNRASV--GLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLEN-LESLDLFTCEVTNL 128
           S N  +   GLE L     NL  LN+S N I DLS + PL  +++ L  +DL +  + ++
Sbjct: 95  SCNLITKVEGLEELI----NLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSI 150

Query: 129 NN 130
           ++
Sbjct: 151 HH 152


>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
          Length = 865

 Score = 37.7 bits (86), Expect = 0.003
 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 5/113 (4%)

Query: 17  SDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRA 76
           +D+  L LD +Q    KLE L ++ + L  L+  N  L  +  + KL  L+ L L  N  
Sbjct: 36  ADIHTLILDKNQII--KLENL-EKCKRLIQLSVANNRLVRMMGVAKLTLLRVLNLPHN-- 90

Query: 77  SVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLN 129
           S+G     ++  +L  LNL+GN +K +  I     L++L+  D    ++ +L+
Sbjct: 91  SIGCVEGLKELVHLEWLNLAGNNLKAMEQINSCTALQHLDLSDNNISQIGDLS 143



 Score = 32.3 bits (72), Expect = 0.11
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 13/114 (11%)

Query: 7   IHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKL 66
           +HLE  N   +++K +   NS +              L+ L+  +  ++ I +L KL  L
Sbjct: 102 VHLEWLNLAGNNLKAMEQINSCT-------------ALQHLDLSDNNISQIGDLSKLVSL 148

Query: 67  KKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
           K L L  N  +      A    +L  L+L+ N+I+DL+ I  L  L  LE L +
Sbjct: 149 KTLLLHGNIITSLRMAPAYLPRSLAILSLAENEIRDLNEISFLASLTELEQLSI 202


>gi|238908508 leucine-rich repeat and death domain-containing
           protein [Homo sapiens]
          Length = 860

 Score = 37.0 bits (84), Expect = 0.004
 Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 12/105 (11%)

Query: 18  DVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIAN----LPKLNKLKKLELSS 73
           ++++LF  N+      +E    + E L  L  +++G   + +    LP L  L+ L L  
Sbjct: 235 NIRQLFFYNNY-----IENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEY 289

Query: 74  NRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESL 118
           N+ +   + L    P LI L+L+GN I  L   + +++L+NLE+L
Sbjct: 290 NQLTTFPKALCF-LPKLISLDLTGNLISSLP--KEIRELKNLETL 331



 Score = 26.9 bits (58), Expect = 4.6
 Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 14/102 (13%)

Query: 31  EGKLEGLTDEFEELELLNTINIGLTSIANLPK----LNKLKKLELSSN---RASVGLEVL 83
           E  L  L  E + L  L  +N+    I+++PK    L  +++L   +N        LE L
Sbjct: 197 ENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFPSDLECL 256

Query: 84  AEKCPNLIHLNLSGNKIKDL-STIEPLKKLE--NLESLDLFT 122
                NL  L+L  NK++ +  T+  LK L   NLE   L T
Sbjct: 257 G----NLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTT 294


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 36.6 bits (83), Expect = 0.006
 Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 20/135 (14%)

Query: 13  NRTPSDVKELFLDNSQSNEGKL-----EGLTDE-------FEELELLNTIN------IGL 54
           N+  +D    F+D +  N   +     +G+TD         ++L +LN  N      +GL
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGL 469

Query: 55  TSIANLPKLNKLKKLELSS--NRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKL 112
               + P   ++++L LS+    +   +  L+E+CPNL +L+L   +      I  +  +
Sbjct: 470 KQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNI 529

Query: 113 ENLESLDLFTCEVTN 127
            +L S+DL   +++N
Sbjct: 530 FSLVSIDLSGTDISN 544



 Score = 26.2 bits (56), Expect = 7.8
 Identities = 13/41 (31%), Positives = 22/41 (53%)

Query: 83  LAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTC 123
           ++E CP ++ LNLS   I + +     +   NL++L L  C
Sbjct: 266 ISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYC 306


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 36.6 bits (83), Expect = 0.006
 Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 20/135 (14%)

Query: 13  NRTPSDVKELFLDNSQSNEGKL-----EGLTDE-------FEELELLNTIN------IGL 54
           N+  +D    F+D +  N   +     +G+TD         ++L +LN  N      +GL
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGL 469

Query: 55  TSIANLPKLNKLKKLELSS--NRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKL 112
               + P   ++++L LS+    +   +  L+E+CPNL +L+L   +      I  +  +
Sbjct: 470 KQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNI 529

Query: 113 ENLESLDLFTCEVTN 127
            +L S+DL   +++N
Sbjct: 530 FSLVSIDLSGTDISN 544



 Score = 26.2 bits (56), Expect = 7.8
 Identities = 13/41 (31%), Positives = 22/41 (53%)

Query: 83  LAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTC 123
           ++E CP ++ LNLS   I + +     +   NL++L L  C
Sbjct: 266 ISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYC 306


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.132    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,241,419
Number of Sequences: 37866
Number of extensions: 151651
Number of successful extensions: 779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 556
Number of HSP's gapped (non-prelim): 305
length of query: 131
length of database: 18,247,518
effective HSP length: 91
effective length of query: 40
effective length of database: 14,801,712
effective search space: 592068480
effective search space used: 592068480
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.