Guide to the Human Genome
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Search of human proteins with 21070997

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21070997 stromal interaction molecule 1 precursor [Homo
sapiens]
         (685 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21070997 stromal interaction molecule 1 precursor [Homo sapiens]  1377   0.0  
gi|41349446 stromal interaction molecule 2 [Homo sapiens]             574   e-164
gi|148746195 trichohyalin [Homo sapiens]                               54   4e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    52   2e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    52   2e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    52   2e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       52   2e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    50   5e-06
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    50   5e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    50   7e-06
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 50   7e-06
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    50   7e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    50   9e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    49   2e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    49   2e-05
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    49   2e-05
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]        48   3e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    48   3e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    48   3e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                47   4e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                47   4e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    47   6e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    47   8e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    46   1e-04
gi|226371725 FCH domain only 2 isoform b [Homo sapiens]                46   1e-04
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              46   1e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       46   1e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       46   1e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        46   1e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    46   1e-04

>gi|21070997 stromal interaction molecule 1 precursor [Homo sapiens]
          Length = 685

 Score = 1377 bits (3563), Expect = 0.0
 Identities = 685/685 (100%), Positives = 685/685 (100%)

Query: 1   MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSED 60
           MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSED
Sbjct: 1   MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSED 60

Query: 61  EKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDL 120
           EKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDL
Sbjct: 61  EKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDL 120

Query: 121 WKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLK 180
           WKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLK
Sbjct: 121 WKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLK 180

Query: 181 MTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEH 240
           MTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEH
Sbjct: 181 MTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEH 240

Query: 241 MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRL 300
           MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRL
Sbjct: 241 MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRL 300

Query: 301 KELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQ 360
           KELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQ
Sbjct: 301 KELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQ 360

Query: 361 YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVT 420
           YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVT
Sbjct: 361 YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVT 420

Query: 421 AALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDM 480
           AALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDM
Sbjct: 421 AALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDM 480

Query: 481 DEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQM 540
           DEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQM
Sbjct: 481 DEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQM 540

Query: 541 SRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELS 600
           SRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELS
Sbjct: 541 SRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELS 600

Query: 601 PSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGS 660
           PSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGS
Sbjct: 601 PSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGS 660

Query: 661 IGEETDSSPGRKKFPLKIFKKPLKK 685
           IGEETDSSPGRKKFPLKIFKKPLKK
Sbjct: 661 IGEETDSSPGRKKFPLKIFKKPLKK 685


>gi|41349446 stromal interaction molecule 2 [Homo sapiens]
          Length = 833

 Score =  574 bits (1480), Expect = e-164
 Identities = 322/659 (48%), Positives = 405/659 (61%), Gaps = 77/659 (11%)

Query: 25  HSHSEKATGTSSGANSEESTAA--------EFCRIDKPLCHSEDEKLSFEAVRNIHKLMD 76
           H    +ATG+++ A S  + AA        + C    P C +E+++ S EA++ IHK MD
Sbjct: 108 HLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMD 167

Query: 77  DDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDE 136
           DD +G ++VEESDEF+RED+ Y D T KHS  H EDK I++EDLWK WK+SEV+NWT+++
Sbjct: 168 DDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLED 227

Query: 137 VVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALD 196
            +QWLI +VELPQYE+ FR   + G  +PR+AV   +   + LK++DRSHRQKLQLKALD
Sbjct: 228 TLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALD 287

Query: 197 TVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQ 256
            VLFGP     HN +KDF+L VSIVIGVGGCWFAY QN+ SKEH+ KMMKDLE L  AEQ
Sbjct: 288 VVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQ 347

Query: 257 SLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKY 316
           SL DLQERL KAQEE+R V VEK +LE+K+ DEIN AK+EA RL+ELREG E E SR++Y
Sbjct: 348 SLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQY 407

Query: 317 AEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVA 376
           AE+ELEQVR AL+KAEKE E  SSW  P+ALQKWLQLTHEVEVQYYNIK+QNAE QL +A
Sbjct: 408 AEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIA 467

Query: 377 KEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEIL 436
           K+ AEKIKKKR+T+FGT HVAHSSSLD+VDHKIL AK+ALSE+T  LRERL RWQQIE +
Sbjct: 468 KDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKI 527

Query: 437 CGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQ 496
           CGFQI +N G+ SL ++L  D SW+   R +   + +   VDD+DE+        +P + 
Sbjct: 528 CGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDED--------TPPIV 579

Query: 497 SSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGS 556
           S     + +P   L     L  S          R+ + P  PQ  RA             
Sbjct: 580 SQFPGTMAKPPGSLARSSSLCRS----------RRSIVPSSPQPQRA------------- 616

Query: 557 HRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGGSPHLDSSRS 616
                        +  P +P                        PS P    PH      
Sbjct: 617 -------------QLAPHAP-----------------------HPSHP--RHPHHPQHTP 638

Query: 617 HSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGSIGEETDSSPGRKKFP 675
           HS  SPDPD  S        +        + + +K     D  S  +  +SS GRK+ P
Sbjct: 639 HSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQWEVPDTASECDSLNSSIGRKQSP 697


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 5/109 (4%)

Query: 238  KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            +E  K+  ++LE  +R E+ +   +E+L + + E R     +  LE++ R+E  L ++E 
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR----RRQELERQYREEEELQQEEE 1181

Query: 298  QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW-YAPE 345
            Q L+E +E    ER RQ   EEEL++ +   R  +++  S   W + PE
Sbjct: 1182 QLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 36/137 (26%), Positives = 68/137 (49%), Gaps = 3/137 (2%)

Query: 253 RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERS 312
           R EQ L   QE   + Q+E R  + E+   +++ R++    +QE +R ++LR   E ER 
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360

Query: 313 RQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEV---QYYNIKKQNA 369
            Q+   E+ E+ RE   + E++L         + L++  QL  E ++   Q    ++Q  
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420

Query: 370 EKQLLVAKEGAEKIKKK 386
            +Q L  ++  E+ ++K
Sbjct: 421 REQQLRREQEEERHEQK 437



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 33/161 (20%), Positives = 77/161 (47%), Gaps = 5/161 (3%)

Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291
           ++ +  +E  ++  +  E   R EQ     +++L + QEE R  ++ +   E++   ++ 
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365

Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351
             ++E +R ++LR   +  R +Q   E++L   RE   + E++L         + L++  
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRREQQLRREQQLRREQ 423

Query: 352 QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEK---IKKKRNT 389
           QL  E E + +  K +   ++  + +E  E+   +K++  T
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 7/156 (4%)

Query: 238  KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            +E  K+  ++ E  +R E+ L   +E+L + + E R     +   E++ R +  L ++E 
Sbjct: 916  EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR----RRQERERQYRKDKKLQQKEE 971

Query: 298  QRLKELREGTENERSRQKYAEEE-LEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
            Q L E  E    +   +KY EEE L+Q  E L + E+E      W      +  LQ   E
Sbjct: 972  QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031

Query: 357  VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392
              ++    K++  E++    +E  E+++++   L G
Sbjct: 1032 QLLREEREKRRLQERERQYREE--EELQQEEEQLLG 1065



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 11/136 (8%)

Query: 238  KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            +E  K+ +++ E  +R E+ L   +E+L   + E R     +  LE++ R E  L ++E 
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETR----RRQELERQYRKEEELQQEEE 1091

Query: 298  QRLKELREGTEN-ERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
            Q L+E  E     ER RQ   EEEL+Q  E L + E+E          + L++  +   E
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR------QELERQYREEEE 1145

Query: 357  VEVQYYNIKKQNAEKQ 372
            V+ +   + ++  EK+
Sbjct: 1146 VQQEEEQLLREEPEKR 1161



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 44/152 (28%), Positives = 72/152 (47%), Gaps = 24/152 (15%)

Query: 238  KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            +E   +  ++LE  +R E+ L   +E+L + + E R     +   E++ R+E  L ++E 
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKR----RRQERERQCREEEELQQEEE 1121

Query: 298  QRLKELRE-GTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
            Q L+E RE     E  RQ   EEE++Q  E L + E E                     E
Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR----------------QE 1165

Query: 357  VEVQYYNIKK-QNAEKQLLVAKEGAEKIKKKR 387
            +E QY   ++ Q  E+QLL  +E  EK +++R
Sbjct: 1166 LERQYREEEELQQEEEQLL--REEQEKRRQER 1195



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/124 (25%), Positives = 63/124 (50%), Gaps = 3/124 (2%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ-E 296
           +E ++K+ +  + L R  Q     Q+RL + Q+  R  E E+   +++ R++    +Q E
Sbjct: 275 EEQLRKLER--QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332

Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
            +R ++LR   E  R +Q   E+E E+  + LR+ ++E          + L++  QL  E
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392

Query: 357 VEVQ 360
            +++
Sbjct: 393 QQLR 396



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 36/157 (22%), Positives = 74/157 (47%), Gaps = 4/157 (2%)

Query: 238  KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            +E  +K  ++ + + R E+    L+E     QE HR    E+  L+++   +++  +++ 
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485

Query: 298  QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357
            + L+E ++    ER R K+ E+EL       +  E+E + H      + LQ+  QL  + 
Sbjct: 1486 KFLEEEQQLRRQERDR-KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544

Query: 358  EVQYY---NIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391
              Q       +K   E+QL   +E  +  +++R+  F
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 23/175 (13%)

Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQE--RLHKAQEEHRTVEVEKVHLEKKLRDE 289
           ++    +E  ++ ++  +   R EQ L   Q+  R  + + E +    +++  E++LR E
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410

Query: 290 INLAK-QEAQRLKELREGTENERSRQKYAEEELEQ-------VREALRKAEKELESHSSW 341
             L + Q+ +R ++LR   E ER  QK+ +E  EQ        R    K E+E E H   
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470

Query: 342 YAPEAL---------QKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387
              + L         ++WL+L  E   +    +++  E+QL   +E   + + KR
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERRE----QQERREQQLRREQEERREQRLKR 521



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 14/115 (12%)

Query: 262 QERLHKAQEEH-----RTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKY 316
           Q+RL + QEE      +  EVE++  E++    +   + E +R ++L +  E E  RQ+ 
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646

Query: 317 AEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEK 371
              E ++ RE   K E+E          E L++ L+  HE E +   + ++  E+
Sbjct: 647 LRREQQERREQRLKREEE---------EERLEQRLKREHEEERREQELAEEEQEQ 692



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 38/155 (24%), Positives = 78/155 (50%), Gaps = 8/155 (5%)

Query: 238  KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTV-EVEKVHLEKKLRDEINLAKQE 296
            +E  +K M+D + L R E      QER  K +E+ + + E E+  L ++ RD   L ++ 
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650

Query: 297  AQRLKELREGTENERSRQKYAEEEL--EQVREALRKAEKE---LESHSSWYAPEALQKWL 351
              R +E  +   ++R R+   EE+L  E   + LR+ E++    E        E  +K+L
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710

Query: 352  QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
            Q   E +++   ++++  E++ L  +   E+++++
Sbjct: 1711 Q--EEQQLRRQELERKFREEEQLRQETEQEQLRRQ 1743



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 31/161 (19%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQER--------LHKAQEEHRTVEVEKVHLEKKLRDE 289
           +E  +++ ++ +GL   ++     ++R        L + ++  R     K  L+++LR E
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902

Query: 290 INLAKQEAQRLK--ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEAL 347
             L ++E + L+  E  +    E+ RQ   EE+L+Q  E L + E+E             
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR--------- 953

Query: 348 QKWLQLTHEVEVQYYNIKK-QNAEKQLLVAKEGAEKIKKKR 387
                   E E QY   KK Q  E+QLL    G E  K++R
Sbjct: 954 -------QERERQYRKDKKLQQKEEQLL----GEEPEKRRR 983



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 41/157 (26%), Positives = 74/157 (47%), Gaps = 6/157 (3%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q R  +   ++  +  + L R E++    QER  + Q+  R  E E+     KL +E   
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQER--RKQQLKRDQEEERRERWLKLEEEERR 497

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
            +QE +  +  RE  E    R K  EEE E++++ LR +E++L         + L++  +
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEE-ERLQQRLR-SEQQLRREQEERREQLLKREEE 555

Query: 353 LTHEVEVQYYNIKKQNAEK--QLLVAKEGAEKIKKKR 387
              E E +   +K++  E+  QLL  +E   + + KR
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 14/138 (10%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKK-LRDEIN 291
           Q+R  +E  +K  +  E + R E+    LQE   + Q E +  E +   LE++ LR E  
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEE--KLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291

Query: 292 LAKQEAQRLK-----------ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS 340
             +Q+ QRL+           E RE  E  R +Q+  E++ E+  + LR+ ++E      
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351

Query: 341 WYAPEALQKWLQLTHEVE 358
               E  ++  QL  E E
Sbjct: 352 RREQEEERREQQLRREQE 369



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 6/135 (4%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           K H  +   D E L R E  L +L+ +  + +++ R    ++V  E+   +E    K+E 
Sbjct: 197 KGHETEEFPDEEQLRRRE--LLELRRKGREEKQQQRRERQDRVFQEE---EEKEWRKRET 251

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357
              KE  +  E E  RQ+  +EE EQ+R+ L + E   E        + L++  QL  + 
Sbjct: 252 VLRKEEEKLQEEEPQRQRELQEEEEQLRK-LERQELRRERQEEEQQQQRLRREQQLRRKQ 310

Query: 358 EVQYYNIKKQNAEKQ 372
           E +    +++  E+Q
Sbjct: 311 EEERREQQEERREQQ 325



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 46/211 (21%), Positives = 89/211 (42%), Gaps = 36/211 (17%)

Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAK 294
           R  +E +++ +K  E     ++   + + +  + +EE R   ++    E++ + ++   +
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651

Query: 295 QE--AQRLK----------ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY 342
           QE   QRLK           L+   E ER  Q+ AEEE EQ RE ++             
Sbjct: 652 QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK------------- 698

Query: 343 APEALQKW-LQLTHEVEVQ----YYNIKKQNAEKQLLVAKEGAEKIKKKRNTL-FGTFHV 396
               + KW  QL  E + +    Y   +KQ  +++    +E  EK +++ + L +     
Sbjct: 699 --SRIPKWQWQLESEADARQSKVYSRPRKQEGQRR---RQEQEEKRRRRESELQWQEEER 753

Query: 397 AHSSSLDDVDHKILTAKQALSEVTAALRERL 427
           AH    ++   +  T +    E +   R+RL
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 38/178 (21%), Positives = 80/178 (44%), Gaps = 23/178 (12%)

Query: 233  QNRYSKEHMKKMMKDLEGLHRAEQSLHDL--QERLHKAQEEHRTVEVEKVHLEKKLRDEI 290
            + ++ +E  +   ++LE   R E+ L     QE+L + +   + +E E++  E   R+E 
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE---REEQ 1762

Query: 291  NLAKQEAQRL----KELREGTENERSRQKYA------EEELEQVREALRKAEKELESHSS 340
             L +QE  R     ++LR+  E ++ R + +      EE+L Q RE  +   ++ +    
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822

Query: 341  W--------YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
            W           + L++     +  E Q+   +K   E+Q L  +E  ++ +++   L
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880



 Score = 37.0 bits (84), Expect = 0.061
 Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 22/177 (12%)

Query: 236  YSKEHMKKMMKDLEGLH-RAEQSLHDLQERLHKAQEEHRTVE-----------VEKVHLE 283
            Y K    +  + LE    R  QS  DLQ  L + QE  R  E            E+  LE
Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE 1300

Query: 284  KKLRDEINLAKQEAQRLKEL-REGTENERSRQ----KYAEEE---LEQVREALRKAEKEL 335
            ++ + E     +++Q  K+L RE  E +R RQ    K+ EEE    E+  + LR+ E++ 
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360

Query: 336  E-SHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391
            +         E  +K+L+    +  Q    +K   E+Q L  +E  +++++ R+  F
Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERE-RKFLKEEQQLRCQEREQQLRQDRDRKF 1416



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 39/159 (24%), Positives = 71/159 (44%), Gaps = 9/159 (5%)

Query: 233  QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
            Q R   +   +   + E L R EQ   + + R  K+QEE + +  E+   EK+ R E + 
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQK--EAKRRDRKSQEEKQLLREERE--EKRRRQETDR 1336

Query: 293  AKQEAQRLKELREGTENERSRQ--KYAEEELEQVREALRKAEKELESHSSWYAPEALQKW 350
              +E ++L + RE     R  +  K+ EEEL    +  +  E+E          + L++ 
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396

Query: 351  LQL---THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
             QL     E +++    +K   E+Q L  +E   K +++
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREE 1435



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 33/155 (21%), Positives = 73/155 (47%), Gaps = 8/155 (5%)

Query: 238  KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            +E  +K +K+ + L   E+     Q+R  K +EE +  ++ +   ++K R+E    +++ 
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ--QLSRQERDRKFREEEQQVRRQE 1443

Query: 298  QRLKELREGTE--NERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355
            +  K L E  +   ER R+   EE+L Q RE  +   +E +        E  Q+  +   
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL----EEEQQLRRQER 1499

Query: 356  EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
            + + +   ++ Q  E++ L  ++   + +++R  L
Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 40/167 (23%), Positives = 78/167 (46%), Gaps = 13/167 (7%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q R  ++  K+  ++ E   + E+  H  Q+     +E+ R    +    EK  R    L
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQE----EEQRRDFTWQWQAEEKSERGRQRL 784

Query: 293 AKQ---EAQRLKELREGTENERSRQKYA--EEELEQVREALRKAEKELESHSSWYAPEAL 347
           + +     QR ++LR   E ++  Q++   EEE EQ R   R+ EKEL+        +  
Sbjct: 785 SARPPLREQRERQLR-AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843

Query: 348 QKWLQLTHEVEVQYYNIKKQNAEKQLLVAK---EGAEKIKKKRNTLF 391
           ++  QL  E +    + +++ +++Q    K   +  E+ K++R+TL+
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY 890



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 14/162 (8%)

Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAK 294
           R+ +E  K+ +K  +   R E+ L  L+E   + Q+E R  ++ +   E++ R E  L +
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLK-LEEEERREQQERREQQLRR---EQEERREQRLKR 521

Query: 295 QEA-QRL-------KELREGTENERSRQKYAEEE--LEQVREALRKAEKELESHSSWYAP 344
           QE  +RL       ++LR   E  R +    EEE  LEQ R   R   ++ E        
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581

Query: 345 EALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
           E  ++  +L  E E +     K+   ++L   +   +++K++
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 37/172 (21%), Positives = 77/172 (44%), Gaps = 18/172 (10%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q R  ++  ++  +  E   + ++    LQ+RL   Q+  R  E  +  L K+  ++   
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559

Query: 293 AKQEAQRLKELRE-------GTENERSRQKYAEEELEQVREALRKAEKE-------LESH 338
            ++  QRLK  +E         E ER +Q+   E+ E++ + L++ E E        E  
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619

Query: 339 SSWYAP--EALQKWLQLTHEVEVQYYNIKKQNAEK--QLLVAKEGAEKIKKK 386
                P  E  Q+ L+   + E +   ++++  E+  Q L  +E  E+++++
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 12/131 (9%)

Query: 249 EGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK----ELR 304
           E L R  Q   + +ER  +A+EE   ++  K H  ++  DE  L ++E   L+    E +
Sbjct: 171 EELWRQRQEWQEREER--RAEEEQ--LQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226

Query: 305 EGTENERSRQKYAEEELEQVRE---ALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQY 361
           +    ER  + + EEE ++ R+    LRK E++L+        E LQ+  +   ++E Q 
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE-LQEEEEQLRKLERQE 285

Query: 362 YNIKKQNAEKQ 372
              ++Q  E+Q
Sbjct: 286 LRRERQEEEQQ 296



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 8/134 (5%)

Query: 255  EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKEL-REGTENERSR 313
            EQ L + +E+  + QE  R    E+  L ++ R+   L +++  R +EL R+  E E+ R
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732

Query: 314  QKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL-QLTHEVEVQYYNIKKQNAEKQ 372
            Q+  +E+L + +E  RK  +E +       PE  ++ L +   + + +     +Q  E+Q
Sbjct: 1733 QETEQEQLRR-QERYRKILEEEQ-----LRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786

Query: 373  LLVAKEGAEKIKKK 386
             L ++E   K +++
Sbjct: 1787 QLRSQESDRKFREE 1800



 Score = 33.9 bits (76), Expect = 0.51
 Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 233  QNRYSKEHMKKMMKDLEGLHRAEQS---LHDLQERLHKAQEEHRTVEVEKVHLEKKLRDE 289
            Q R  +E  +   +  +G +R E+    L + ++RL + ++     E +    EK  R+E
Sbjct: 1802 QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861

Query: 290  INLAKQEAQRLKELREG--TENERSRQKYAEEELEQVRE 326
              L ++E Q+ ++ RE    E    RQ+  E+   QV E
Sbjct: 1862 QELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900



 Score = 33.5 bits (75), Expect = 0.67
 Identities = 34/149 (22%), Positives = 66/149 (44%), Gaps = 14/149 (9%)

Query: 249 EGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTE 308
           +G    +Q   + Q+R+ + +EE    + E V      ++E  L ++E QR +EL+E  E
Sbjct: 221 KGREEKQQQRRERQDRVFQEEEEKEWRKRETV----LRKEEEKLQEEEPQRQRELQEEEE 276

Query: 309 NERS-------RQKYAEEELEQ---VREALRKAEKELESHSSWYAPEALQKWLQLTHEVE 358
             R        R++  EE+ +Q     + LR+ ++E          E  ++  Q     E
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336

Query: 359 VQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387
            Q    +++  E+QL   +E   + ++ R
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLR 365



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 32/155 (20%), Positives = 69/155 (44%), Gaps = 6/155 (3%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           +   K+  ++ E     EQS  + QERL +   + R  E+ +   E + R+E    +++ 
Sbjct: 136 RRRQKRQEQERELAEGEEQS--EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL 193

Query: 298 QRLK--ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355
           Q  K  E  E  + E+ R++   E   + RE   K ++  E     +  E  ++W +   
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGRE--EKQQQRRERQDRVFQEEEEKEWRKRET 251

Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
            +  +   ++++  ++Q  + +E  +  K +R  L
Sbjct: 252 VLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 33/157 (21%), Positives = 72/157 (45%), Gaps = 28/157 (17%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           +   ++  K+L+ L   EQ     +ER  + QEE   ++           D+     QE 
Sbjct: 821 RRQRREREKELQFLEEEEQLQR--RERAQQLQEEEDGLQ----------EDQERRRSQEQ 868

Query: 298 QRLKELREGTENERSRQKYA-------EEELEQVREALRKAEKELESHSSWYAPEALQKW 350
           +R ++ R   E ER R+++        +E+L + ++ L++ E+EL+           ++ 
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE---------ERE 919

Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387
            +   E E QY   ++   E++ L+ +E  ++ +++R
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 30/155 (19%), Positives = 72/155 (46%), Gaps = 11/155 (7%)

Query: 242 KKMMKDLEGLHRAEQSLHDLQERLH--KAQEEHRTVEVEKVHLEK----KLRDEINLAKQ 295
           ++ ++  + L R +Q   + +E  H  K ++E R   +++   E+    K  +E    +Q
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469

Query: 296 EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ--- 352
           E ++ +  R+  E  R R    EE  E+ RE   + E++L         + L++  +   
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEE--EERREQQERREQQLRREQEERREQRLKRQEEEER 527

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387
           L   +  +    ++Q   ++ L+ +E  ++++++R
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 37/159 (23%), Positives = 71/159 (44%), Gaps = 19/159 (11%)

Query: 233  QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
            Q   S+E  +K +++       EQ LH  Q +    QEE +    E+    ++ RD    
Sbjct: 1506 QELRSQEPERKFLEE-------EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558

Query: 293  AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
             +++ ++ +E ++ +  ER R+   EE+  + +E  RK    +E        E  Q   Q
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKF---MEDEQQLRRQEGQQ---Q 1612

Query: 353  LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391
            L  E +      +K   ++QLL  +E  +  +++R+  F
Sbjct: 1613 LRQERD------RKFREDEQLLQEREEQQLHRQERDRKF 1645



 Score = 29.6 bits (65), Expect = 9.7
 Identities = 39/136 (28%), Positives = 63/136 (46%), Gaps = 25/136 (18%)

Query: 262 QERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEEL 321
           Q R  K QE+ R +   +   EK+ R    L +++ QR  E     E  R RQ++ E   
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQER----LEQRDRQRRDE-----ELWRQRQEWQE--- 182

Query: 322 EQVREALRKAEKELES---HSSWYAPEALQ----KWLQLTHEVEVQYYNIKKQNAEKQLL 374
              RE  R  E++L+S   H +   P+  Q    + L+L  +   +    ++Q  E+Q  
Sbjct: 183 ---REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK---QQQRRERQDR 236

Query: 375 VAKEGAEKIKKKRNTL 390
           V +E  EK  +KR T+
Sbjct: 237 VFQEEEEKEWRKRETV 252


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 39/208 (18%), Positives = 92/208 (44%), Gaps = 11/208 (5%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKA----------QEEHRTVEVEKVHLEKKLR 287
           +E   +M +  E +   EQ + D +ER+ K           QEE    E      EKK+R
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599

Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREAL-RKAEKELESHSSWYAPEA 346
           +E  + +++ ++++E  E  + +  +    EE++++  E +  + EK  E     +  + 
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659

Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406
           L +  +   E E      K Q  E+++   ++  +K +++    +    +    S+ + +
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719

Query: 407 HKILTAKQALSEVTAALRERLHRWQQIE 434
            K+   ++ + E    ++E+  + Q+ E
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQE 747



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 43/209 (20%), Positives = 93/209 (44%), Gaps = 15/209 (7%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  KK+ K  E + R E       ERL + + + R  E +    EK+LR++   
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQE-------ERLREQEGKMREQEEKMWRQEKRLREQEKE 329

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQKW 350
            +++ + L+E +E  E E   Q+  E+  EQ  E +R+ E+++  +    W   + +++ 
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQ-EEKMREQEEKMWRQEERLWEQEKQMREQ 388

Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAK-----EGAEKIKKKRNTLFGTFHVAHSSSLDDV 405
            Q   + E + +   ++  EK+  + +     E  EK+++++                  
Sbjct: 389 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE 448

Query: 406 DHKILTAKQALSEVTAALRERLHRWQQIE 434
           + +I   ++ + E    +RE+  + Q+ E
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQE 477



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 40/148 (27%), Positives = 70/148 (47%), Gaps = 8/148 (5%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           E  K+M +  + +   E+ + +  ERL + +E  R  E     +EK +R+E  + +QE +
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK-MREEKKMQEQEKK 438

Query: 299 RLKELREGTENE--RSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
              +  +  E E  R R+K   EE E +RE   K +K+ E  + W   E   +  +L  +
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE--NMWEQEEKEWQQQRLPEQ 496

Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIK 384
            E  +   K Q  E+++    E  EKI+
Sbjct: 497 KEKLWEQEKMQEQEEKIW---EQEEKIR 521



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 47/201 (23%), Positives = 92/201 (45%), Gaps = 21/201 (10%)

Query: 238 KEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296
           K  ++  +K+L+  L RA+  L  +Q   +  QEE    E E    EKK+R +     ++
Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQT--NTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298

Query: 297 AQRLKELREGTENERSRQKYAEEE-LEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355
            +RL+E +EG   E+  + + +E+ L +  + LR+ EKEL         E  ++  Q+  
Sbjct: 299 EERLRE-QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK-----ELREQEEQMQE 352

Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGA--EKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAK 413
           + E  +   +K   +++ +  +E    E+ K+ R              + D + ++    
Sbjct: 353 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE---------QEQKMRDQEERMWEQD 403

Query: 414 QALSEVTAALRERLHRWQQIE 434
           + L E    +RE+   W+Q+E
Sbjct: 404 ERLREKEERMREQEKMWEQVE 424



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/162 (19%), Positives = 79/162 (48%), Gaps = 12/162 (7%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQE-EHRTVEVEKVH-------LEKKLRDEI 290
           EH K  M++ E +   E+ + + ++   K QE E +T + EK+         EKK+R+E 
Sbjct: 669 EHEK--MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726

Query: 291 NLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKW 350
            + +++ ++++E  E  + +       EE++ +  E + + ++  E     +  E +Q+ 
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 786

Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392
            ++  + E      +K   +++ +  +E  EK++ +   ++G
Sbjct: 787 EKIWEQEEKMRDQEEKMRGQEEKMRGQE--EKMRGQEEKMWG 826



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 31/146 (21%), Positives = 68/146 (46%), Gaps = 3/146 (2%)

Query: 235 RYSKEHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293
           R  +E M++  K  E + +  E+     QE+  + QEE    E      EKK+R+E    
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKWLQ 352
           +++ +++++  E    E+  +++ ++ L + +E L + EK  E     W   E ++   +
Sbjct: 467 REQEEKMQKQEENMW-EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKE 378
           +  + +  +   K +  E Q+   +E
Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEE 551



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 25/115 (21%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           +E  KKM ++ E +   E+ + + +E++ + +EE    E +    E+K+ ++  L +Q+ 
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK- 774

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
           ++L E  +  E E+  ++  EE++    E +R  E+++         +  + W Q
Sbjct: 775 EKLWEHEKMQEQEKIWEQ--EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 37/200 (18%), Positives = 92/200 (46%), Gaps = 13/200 (6%)

Query: 242 KKMMKDLEGLHRAEQSLHD---LQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           KKM +  +     E+ + +   ++ER  K +EE  T+  ++   EK  + E N+ +QE  
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE---EKMQKQEENMWEQEE- 485

Query: 299 RLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVE 358
             KE ++    E+  + + +E++++  E + + E+++      +  E      +   E E
Sbjct: 486 --KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543

Query: 359 VQYY--NIKKQNAEKQLLVAKEGAEK--IKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQ 414
            Q +    K ++ E+++   +E  EK   ++++ T      +     + + + K+   ++
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603

Query: 415 ALSEVTAALRERLHRWQQIE 434
            + E    ++E+  + Q+ E
Sbjct: 604 MMREQEEKMQEQEEKMQEQE 623


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 41/173 (23%), Positives = 81/173 (46%), Gaps = 3/173 (1%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q +  +E  +K+ +  E + R E+ + +L+E +   +E+ R VE +    E+K++++   
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY-APEALQKWL 351
            +++ ++++E  E T  +    K  E+  EQ  +  R+ EK  E         E +Q+  
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530

Query: 352 QLTHEVEVQYY--NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSL 402
           +   E EV+ +    K Q  E +L   +E   K+ +K   L G    + S  L
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 39/202 (19%), Positives = 95/202 (47%), Gaps = 23/202 (11%)

Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDEINL 292
           N  +++  +KM +  E +   E+ + + QE   + QEE    + EK+H  E+K+R++ + 
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCE-QELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
             ++ ++++E  E    +  +    EE++ +  E +++ E+E+     W   E +++  +
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM-----WRQEEKIREQEE 402

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTA 412
              E        K    EK++   +E  EKI+++   ++          + +++  +   
Sbjct: 403 KRQE--------KMWRQEKKM---REQDEKIREQEEEMW-----RQEEKIRELEEMMQDQ 446

Query: 413 KQALSEVTAALRERLHRWQQIE 434
           ++ L EV   ++E   + Q+ E
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQE 468



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 29/169 (17%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQER-----------LHKAQEEHRTVEVEKVH 281
           Q    +E  +K+ +  E + R E+ + + +E+           + +  E+ R  E E   
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431

Query: 282 LEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW 341
            E+K+R+   + + + ++L+E+ E  + E  + +  EE++++  E +++ E++     +W
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK-----TW 486

Query: 342 YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
              + L++  ++  + E  +   +K   +++ +  +E  EK++++   +
Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKM--QEQEEKMQRQEEKM 533



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 27/153 (17%), Positives = 75/153 (49%), Gaps = 2/153 (1%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +    +   E+ +   +E++H+ +E+ R  E +    E+K+R++   
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
            +++ +++    E    +  + +  EEE+ +  E +R+ E E      W   + +++  +
Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDE 420

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKK 385
              E E + +  +++  E + ++ ++  EK+++
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMM-QDQEEKLRE 452



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 42/209 (20%), Positives = 97/209 (46%), Gaps = 20/209 (9%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +  E +   ++ + + +E + + +E+ R  E E+   EK  R E  +
Sbjct: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR--EQEEKRQEKMWRQEKKM 415

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQV----REALRKAEKEL--ESHSSWYAPEA 346
            +Q+    +++RE  E E  RQ+    ELE++     E LR+ E+++  E        E 
Sbjct: 416 REQD----EKIRE-QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470

Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406
           +Q+  +   E E + +  +K   +++ +  +E  EK+ ++   ++          + + +
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--EKMWRQEEKMW-----EQEEKMQEQE 523

Query: 407 HKILTAKQALSEVTAALRERLHRWQQIEI 435
            K+   ++ + E    L ++  + Q+ E+
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEV 552



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 37/200 (18%), Positives = 92/200 (46%), Gaps = 21/200 (10%)

Query: 240 HMKKMMKDLEG----LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295
           +++K+ K+ +     L+R   +  +L+E+  + QE+ R VE EK  ++  ++D     K+
Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKD----LKR 246

Query: 296 EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355
           + +R + L      ++  Q  A+   ++++    K + ++E +  W      Q+      
Sbjct: 247 KLERAQLLLP----QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302

Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415
           E ++Q    +++   +Q L  +E  EK+ ++   +           + + + K+   ++ 
Sbjct: 303 EEKIQE---QEEKMCEQELKIREQEEKMWRQEEKMH-----EQEEKIREQEDKMWRQEEK 354

Query: 416 LSEVTAALRERLHR-WQQIE 434
           + E    +RE+  + W+Q E
Sbjct: 355 IREQEEKIREQEEKMWRQEE 374


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 41/173 (23%), Positives = 81/173 (46%), Gaps = 3/173 (1%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q +  +E  +K+ +  E + R E+ + +L+E +   +E+ R VE +    E+K++++   
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY-APEALQKWL 351
            +++ ++++E  E T  +    K  E+  EQ  +  R+ EK  E         E +Q+  
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530

Query: 352 QLTHEVEVQYY--NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSL 402
           +   E EV+ +    K Q  E +L   +E   K+ +K   L G    + S  L
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 39/202 (19%), Positives = 95/202 (47%), Gaps = 23/202 (11%)

Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDEINL 292
           N  +++  +KM +  E +   E+ + + QE   + QEE    + EK+H  E+K+R++ + 
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCE-QELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
             ++ ++++E  E    +  +    EE++ +  E +++ E+E+     W   E +++  +
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM-----WRQEEKIREQEE 402

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTA 412
              E        K    EK++   +E  EKI+++   ++          + +++  +   
Sbjct: 403 KRQE--------KMWRQEKKM---REQDEKIREQEEEMW-----RQEEKIRELEEMMQDQ 446

Query: 413 KQALSEVTAALRERLHRWQQIE 434
           ++ L EV   ++E   + Q+ E
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQE 468



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 29/169 (17%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQER-----------LHKAQEEHRTVEVEKVH 281
           Q    +E  +K+ +  E + R E+ + + +E+           + +  E+ R  E E   
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431

Query: 282 LEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW 341
            E+K+R+   + + + ++L+E+ E  + E  + +  EE++++  E +++ E++     +W
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK-----TW 486

Query: 342 YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
              + L++  ++  + E  +   +K   +++ +  +E  EK++++   +
Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKM--QEQEEKMQRQEEKM 533



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 27/153 (17%), Positives = 75/153 (49%), Gaps = 2/153 (1%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +    +   E+ +   +E++H+ +E+ R  E +    E+K+R++   
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
            +++ +++    E    +  + +  EEE+ +  E +R+ E E      W   + +++  +
Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDE 420

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKK 385
              E E + +  +++  E + ++ ++  EK+++
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMM-QDQEEKLRE 452



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 42/209 (20%), Positives = 97/209 (46%), Gaps = 20/209 (9%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +  E +   ++ + + +E + + +E+ R  E E+   EK  R E  +
Sbjct: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR--EQEEKRQEKMWRQEKKM 415

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQV----REALRKAEKEL--ESHSSWYAPEA 346
            +Q+    +++RE  E E  RQ+    ELE++     E LR+ E+++  E        E 
Sbjct: 416 REQD----EKIRE-QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470

Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406
           +Q+  +   E E + +  +K   +++ +  +E  EK+ ++   ++          + + +
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--EKMWRQEEKMW-----EQEEKMQEQE 523

Query: 407 HKILTAKQALSEVTAALRERLHRWQQIEI 435
            K+   ++ + E    L ++  + Q+ E+
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEV 552



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 37/200 (18%), Positives = 92/200 (46%), Gaps = 21/200 (10%)

Query: 240 HMKKMMKDLEGL----HRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295
           +++K+ K+ + L    +R   +  +L+E+  + QE+ R VE EK  ++  ++D     K+
Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKD----LKR 246

Query: 296 EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355
           + +R + L      ++  Q  A+   ++++    K + ++E +  W      Q+      
Sbjct: 247 KLERAQLLLP----QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302

Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415
           E ++Q    +++   +Q L  +E  EK+ ++   +           + + + K+   ++ 
Sbjct: 303 EEKIQE---QEEKMCEQELKIREQEEKMWRQEEKMH-----EQEEKIREQEDKMWRQEEK 354

Query: 416 LSEVTAALRERLHR-WQQIE 434
           + E    +RE+  + W+Q E
Sbjct: 355 IREQEEKIREQEEKMWRQEE 374


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 10/144 (6%)

Query: 254 AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKK--LRDEINLAKQEAQRLKELREGTENER 311
           AE+     +E    A+E  R  E EK   E++  +++E   A +E QR+KE  +    ER
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370

Query: 312 SRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEK 371
            R +  EEE  +V E  R  + E + H+     E   K  ++  ++E ++ N KK   +K
Sbjct: 371 QRARAEEEEKAKVEEQKRNKQLEEKKHA---MQETKIKGEKVEQKIEGKWVNEKKAQEDK 427

Query: 372 --QLLVAKEGAE---KIKKKRNTL 390
               ++ K+G E   K++ KR  L
Sbjct: 428 LQTAVLKKQGEEKGTKVQAKREKL 451



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/165 (21%), Positives = 71/165 (43%), Gaps = 23/165 (13%)

Query: 240 HMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLE---------------- 283
           H +KM ++ +    AE++  + +ER     E+ + +  E+  +E                
Sbjct: 253 HHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAE 312

Query: 284 --KKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW 341
             +++R+E   A +E QR+KE  +    ER R K  E+   + R+ +++ EK        
Sbjct: 313 ERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 372

Query: 342 YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
              E  +K      +VE Q  N + +  +  +   K   EK+++K
Sbjct: 373 ARAEEEEK-----AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 12/97 (12%)

Query: 237 SKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296
           S+E  K   K  E     E+     +ER    +EE +  + E+   ++KLR+E     +E
Sbjct: 548 SEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA--DRKLREE-----EE 600

Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333
            +RLKE     E ER R + AE+  +   + L   +K
Sbjct: 601 KRRLKE-----EIERRRAEAAEKRQKMPEDGLSDDKK 632


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 28/159 (17%), Positives = 84/159 (52%), Gaps = 6/159 (3%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    ++  +KM +  E +H  E+ + + +E++ + +E+ R  E +    E+K+R++  +
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
            +++ +++ E  E    +  + +  EE++ +  E +R+ EK++         E +++  +
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE-----EKIREQEE 662

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391
           +  E E + +  +++  E++  + +E  EK++++   ++
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKM-QEQEEKMRRQEEKMW 700



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 37/157 (23%), Positives = 81/157 (51%), Gaps = 13/157 (8%)

Query: 233 QNRYSKEHMKKMMKDLEG---LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDE 289
           + R  +E +++  K  E    + R E+ + + +E++ + QEE    + EK+H ++K+R+E
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEEKMWRQEEKIHEQEKIREE 516

Query: 290 INLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK 349
               +QE    +E +   + E  RQK   E++ +  E +RK E+++     W   E +  
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQK---EKIHEQEEKIRKQEEKM-----WRQEEKMHD 568

Query: 350 WLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
             +   E E + +  +++  E++  + +E  EKI+++
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKI-REQEEKIREQ 604



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 28/137 (20%), Positives = 70/137 (51%), Gaps = 4/137 (2%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV-HLEKKLRDEINLAKQEA 297
           +H+ K ++ +    +A+   ++L  RL++ QEE    + EK+   E+K++++    +++ 
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQKWLQLTH 355
           ++++E  E    +       EE++ +  E + + E+++  +    W   E +++  +  H
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448

Query: 356 EVE-VQYYNIKKQNAEK 371
           E E ++    K+Q  EK
Sbjct: 449 EQEKIREQEEKRQEEEK 465



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 42/210 (20%), Positives = 103/210 (49%), Gaps = 21/210 (10%)

Query: 233 QNRYSKEHM---KKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRD 288
           + R  +E M   ++ +++ E + R ++ +H+ +E++ K QEE    + EK+H  E+K+R+
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK-QEEKMWRQEEKMHDQEEKIRE 575

Query: 289 EINLAKQEAQRLKE----LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAP 344
           +     ++ ++++E    +RE  E  R +++  +E+ E++ E   + EK  E        
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE---QEEKMCEQEEKMQEQ 632

Query: 345 EALQKWLQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSL 402
           E  +K  +   ++  Q   I++Q  +  +Q  + +E  EK+ ++   +           +
Sbjct: 633 E--EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM-----CEQEEKM 685

Query: 403 DDVDHKILTAKQALSEVTAALRERLHRWQQ 432
            + + K+   ++ + E    LR++  + Q+
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 45/220 (20%), Positives = 101/220 (45%), Gaps = 26/220 (11%)

Query: 235 RYSKEHMKK----MMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDE 289
           R  +E M++    M +  E + R E+ + + +E++ + QEE    + EK+  LE+K+ ++
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQ 450

Query: 290 INLAKQEAQRLKELREGTENERSRQK----YAEEELEQVREALRKAEKELESHSSWYAPE 345
             + +QE +R +E +   + +R  Q+      EE++ +  E +R+ E+++     W   E
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM-----WRQEE 505

Query: 346 ALQKWLQLTHEVEVQYYNIKKQNAEK---------QLLVAKEGAEKIKKKRNTLFGTFHV 396
            + +  ++  E + Q      +  EK         Q     E  EKI+K+   ++     
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565

Query: 397 AH--SSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIE 434
            H     + + + K+   ++ + E    +RE+  + ++ E
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/143 (21%), Positives = 72/143 (50%), Gaps = 5/143 (3%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           +E  +K+ +  E +   E+ +   +E + + +E+ R  E      E+K+R +  +  ++ 
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437

Query: 298 QRLKELREGT-ENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKWLQLTH 355
           ++++EL E   E E+ R+   +EE  Q  E +R+ EK  E  +  W   E +++  +   
Sbjct: 438 EKIRELEEKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494

Query: 356 EVEVQYYNIKKQNAEKQLLVAKE 378
           E E + +  +++  E++ +  +E
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEE 517



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 22/113 (19%), Positives = 59/113 (52%), Gaps = 7/113 (6%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q   ++E  +KM +  E +   E+ + + +E++ + +E+ R  E +    E+K+R++  +
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVRE-------ALRKAEKELESH 338
            +++ +++ E  E    +  + +  EE++ +  E        LR+ E++++ H
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 716



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 11/157 (7%)

Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293
           +RY +E  K+       L+R   +  +L+E+  K QE+ + VE EK         EI L 
Sbjct: 253 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 304

Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353
            +E +R  E  +    ++  Q  A+   ++++    K + ++E +  W      Q+    
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364

Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
             E ++Q +  K Q  E+++   +E  EKI+++   +
Sbjct: 365 RQEEKIQEWEEKIQEQEEKI---REQEEKIREQEEKM 398



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 18/99 (18%), Positives = 50/99 (50%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +  E +   E+ + + +E++ + +E  +  E +    E+K+ ++   
Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKA 331
            +++ ++++   E    +  R +  EE++++ +E L  A
Sbjct: 685 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 723


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 36/107 (33%), Positives = 63/107 (58%), Gaps = 7/107 (6%)

Query: 242 KKMMKDLEGLHRAEQSLHD---LQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           ++ +++ + L R  Q LH+   L+E+  KAQEE R ++ EK    KK ++E     +E  
Sbjct: 55  EQQLEEEKLLERERQRLHEEWLLREQ--KAQEEFR-IKKEKEEAAKKRQEEQERKLKEQW 111

Query: 299 RLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPE 345
             ++ +E  E E+ RQ+  E+E E +++ L +AE ELE+ ++W  PE
Sbjct: 112 EEQQRKEREEEEQKRQEKKEKE-EALQKMLDQAENELENGTTWQNPE 157


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 32/141 (22%), Positives = 72/141 (51%), Gaps = 5/141 (3%)

Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293
           NR +++  +KM +  E +   E+ + + +E++ + +E+ R  E      E+K+R +  + 
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 339

Query: 294 KQEAQRLKELREGT-ENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKWL 351
            ++ ++++EL E   E E+ R+   +EE  Q  E +R+ EK  E  +  W   E +++  
Sbjct: 340 WEKEEKIRELEEKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 396

Query: 352 QLTHEVEVQYYNIKKQNAEKQ 372
           +   E E      +++  E++
Sbjct: 397 EKIREQEEMMQEQEEKMGEQE 417



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 27/158 (17%), Positives = 82/158 (51%), Gaps = 6/158 (3%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +  E +   E+ + + +E++ + +E+ R  E +    E+K+R++  +
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352
            +++ +++ E       + ++ +  EE++ +  E +R+ EK++         E +++  +
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE-----EKIREQEE 516

Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
           +  E E + +  +++  E++  + +E  EK++++   +
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKM-QEQEEKMRRQEEKM 553



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 41/220 (18%), Positives = 99/220 (45%), Gaps = 34/220 (15%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLH----------KAQEEHRTVEVEKVH------- 281
           E  +KM +  E +   E+ + +L+E++H          K QEE +  E EK         
Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386

Query: 282 -LEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS 340
             E+K+R++    +++ + ++E  E    +  +    EEE+++  E +R+ E+++     
Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446

Query: 341 WY--APEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAH 398
                 E +++  ++  E E +    + +  E++  + +E  EK++++            
Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM-QEQEEKMRRQ------------ 493

Query: 399 SSSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIEILC 437
              + + + KI   ++ + E    ++E+  + W+Q E +C
Sbjct: 494 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 29/154 (18%), Positives = 77/154 (50%), Gaps = 5/154 (3%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV-HLEKKLRDEINLAKQEA 297
           +H+ K ++ +    +A+   ++L  RL++ QEE    + EK+   E+K++++    +++ 
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE 315

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL-ESHSSWYAPEALQKWLQLTHE 356
           ++++   E    +  + +  EE + +  E +R+ E+++ E        E  Q+  ++  +
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375

Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
            + Q    K    E+++   +E  EKI+++   +
Sbjct: 376 EKRQEQEAKMWRQEEKI---REQEEKIREQEEMM 406



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 20/103 (19%), Positives = 52/103 (50%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +    +   E  + + +E++ + +E+ R  E +    E+K+R++  +
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335
            +++ +++ E  E    +  + +  EE++ +  E +R+ E  L
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 35/158 (22%), Positives = 72/158 (45%), Gaps = 11/158 (6%)

Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293
           +RY +E  K+       L+R   +  +L+E+  K QE+ + VE EK         EI L 
Sbjct: 180 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 231

Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353
            +E +R  E  +    ++  Q  A+   ++++    K + ++E +  W      Q+    
Sbjct: 232 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291

Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391
             E ++Q    K Q  E+++   +E  EK++++   ++
Sbjct: 292 RQEEKIQEREEKIQEQEEKI---REQEEKMRRQEEMMW 326



 Score = 33.9 bits (76), Expect = 0.51
 Identities = 15/91 (16%), Positives = 46/91 (50%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +  E +   E+ + + +E++ + +E  +  E +    E+K+ ++   
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQ 323
            +++ ++++   E    +  R +  EE++++
Sbjct: 539 MQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 49/188 (26%), Positives = 88/188 (46%), Gaps = 33/188 (17%)

Query: 255 EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENE---- 310
           EQSL  L+ERL KA EE                +E  + ++E+QRL  LR   ++     
Sbjct: 641 EQSLSSLRERLQKAIEE----------------EEARMREEESQRLSWLRAQVQSSTQAD 684

Query: 311 ----RSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKK 366
               R+ Q+ + ++L +  E+ +KAE+      +    E L++ ++ + + E    N  K
Sbjct: 685 EDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK 744

Query: 367 QNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRER 426
           + A +QL       E+++ +R     T    HS+ L+ +    L AK    EV ++L+++
Sbjct: 745 EKALQQL------REQLEGERKEAVATLEKEHSAELERLCSS-LEAKH--REVVSSLQKK 795

Query: 427 LHRWQQIE 434
           +   QQ E
Sbjct: 796 IQEAQQKE 803



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 12/161 (7%)

Query: 234  NRYSKEHMKKMMKDLEGLHRAEQS-----LHDLQERLHKAQEEH-RTVEVEKVHLEKKLR 287
            ++  +EH + M K  E     E+      L  L   L + Q  H R +E  +    K+L 
Sbjct: 852  DKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLE 911

Query: 288  DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK----ELESHSSWYA 343
            D     +++ ++L++L    E  R++   A   L +V+E   + EK    +++   +  +
Sbjct: 912  DLRRRHREQERKLQDLELDLET-RAKDVKARLALLEVQEETARREKQQLLDVQRQVALKS 970

Query: 344  PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIK 384
             EA     QL  E + ++ ++ + N + + ++ +  A K+K
Sbjct: 971  EEATATHQQL-EEAQKEHTHLLQSNQQLREILDELQARKLK 1010


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 13/186 (6%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           KE  ++M +  +    A Q    +  +  + ++E   +  EK  LEKKLRD     ++  
Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNT 347

Query: 298 QRLKELREGTENERSRQKYAEEELEQVR--EALRKAEKELESHSSWYAPEALQKWLQLTH 355
            ++K+L +  E  R  Q Y  +E E  R    + K ++++ SH          KW Q   
Sbjct: 348 NKIKQLSQ--EKGRLHQLYETKEGETTRLIREIDKLKEDINSH------VIKVKWAQNKL 399

Query: 356 EVEVQYYNIKKQNAEK---QLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTA 412
           + E+  +   K   ++   +L  AKE A++I+K    +  T+  +     +++D K+   
Sbjct: 400 KAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVT 459

Query: 413 KQALSE 418
           K  L +
Sbjct: 460 KGELEK 465



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 53/255 (20%), Positives = 113/255 (44%), Gaps = 29/255 (11%)

Query: 253 RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKE---------- 302
           R E  L   +E +++ + E + + ++KV    +L++++   KQE + LKE          
Sbjct: 514 RTEDELSKYKEIINRQKAEIQNL-LDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLIN 572

Query: 303 -LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQY 361
            L++  E  R R    E EL    E L     +L+S S+    +   K      +++ Q 
Sbjct: 573 DLQKDIEGSRKR----ESELLLFTERLTSKNAQLQSESNSLQSQ-FDKVSCSESQLQSQC 627

Query: 362 YNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG------TFHVAHSSSLDDVDHKILTAKQ- 414
             +K+ N   +  + KE  E  K++  TL        T   A S+ ++++  +++T ++ 
Sbjct: 628 EQMKQTNINLESRLLKE-EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686

Query: 415 ---ALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVA-ALNIDPSWMGSTRPNPAH 470
              ++ ++T  L++   +  Q+E     + V++ G  S  + +LN   S    +  N   
Sbjct: 687 HASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARSSAEDRSPENTGS 746

Query: 471 FIMTDDVDDMDEEIV 485
            +  D+   +D+ ++
Sbjct: 747 SVAVDNFPQVDKAML 761



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 35/188 (18%), Positives = 84/188 (44%), Gaps = 27/188 (14%)

Query: 237 SKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296
           +KE   ++ K+ + + +  Q   ++     K+ E    + V K  LEK+++++ +  +  
Sbjct: 423 AKEEADQIRKNCQDMIKTYQESEEI-----KSNELDAKLRVTKGELEKQMQEKSDQLEMH 477

Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
             ++KEL    E+ +   K   +EL  +R  ++  E E          + L K+ ++ + 
Sbjct: 478 HAKIKEL----EDLKRTFKEGMDELRTLRTKVKCLEDE-----RLRTEDELSKYKEIINR 528

Query: 357 VEVQYYNI-----KKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILT 411
            + +  N+          ++QL   K+  E +K++  +L        +S ++D+   I  
Sbjct: 529 QKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESL--------NSLINDLQKDIEG 580

Query: 412 AKQALSEV 419
           +++  SE+
Sbjct: 581 SRKRESEL 588


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 36/167 (21%), Positives = 80/167 (47%), Gaps = 13/167 (7%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q +  ++  +KM +  E L   E  + + +E++ + ++  R  E E    EK+LR++  L
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL---------ESHSSWYA 343
            +QE Q ++E  E    +  + +  EE++ +  E L + EK++         +    W  
Sbjct: 306 REQEEQ-MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364

Query: 344 PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
            E L++  +   E E  +   +K   E+++   +E  +K++++  T+
Sbjct: 365 DERLREKEERMREQEKMWEQEEKMQEEERI---REREKKMREEEETM 408



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 41/208 (19%), Positives = 95/208 (45%), Gaps = 22/208 (10%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQ----EEHRTVEVEKVH-LEKKLR 287
           Q +  +E  +KM    E +   ++ L + +ER+ + +    +E +  E E++   EKK+R
Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402

Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEA 346
           +E    +++ +++++  E    E+  +++ ++ L + +E L + EK  E     W   E 
Sbjct: 403 EEEETMREQEEKMQKQEENMW-EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461

Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406
           ++   ++  + +  +   K +  E Q+    E  EK++ +   ++            D +
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMW---EQEEKMRDQEQKMW------------DQE 506

Query: 407 HKILTAKQALSEVTAALRERLHRWQQIE 434
            ++    + L E    +RE+   WQQ E
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEE 534



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 35/152 (23%), Positives = 77/152 (50%), Gaps = 6/152 (3%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           +E  ++M +  E +   E+ + + +E++ + +E     E +    E+K+RD+     ++ 
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365

Query: 298 QRLKELREGTENERSRQK-YAEEELEQVREALRKAEKEL--ESHSSWYAPEALQKWLQLT 354
           +RL   RE  E  R ++K + +EE  Q  E +R+ EK++  E  +     E +QK  +  
Sbjct: 366 ERL---REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422

Query: 355 HEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
            E E + +  ++   +K+ L  +E  ++ ++K
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 22/129 (17%), Positives = 62/129 (48%), Gaps = 9/129 (6%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV---------HLE 283
           Q    +E  +KM +  E +   E+ + + +E++ + +EE +  E E++           E
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645

Query: 284 KKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYA 343
           +K+ ++    +++ ++++E  E  + +  + +  EE+++   E +R+ E+++        
Sbjct: 646 EKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMW 705

Query: 344 PEALQKWLQ 352
            +  + W Q
Sbjct: 706 GQEEKMWGQ 714



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 36/224 (16%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQS--------LHDLQERLHKA------------QEEH 272
           +N  + E +KK   +L+   R  +S        + +L+ +L +A            QEE 
Sbjct: 177 RNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 236

Query: 273 RTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAE 332
              E E    EKK+R +     ++ +RL+E       +  + +  E+ L +  + LR+ E
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296

Query: 333 KELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGA--EKIKKKRNTL 390
           KEL         E      Q+  + E  +   +K   +++ +  +E    E+ K+ R   
Sbjct: 297 KELREQKKLREQEE-----QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE-- 349

Query: 391 FGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIE 434
                      + D + ++    + L E    +RE+   W+Q E
Sbjct: 350 -------QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 33/165 (20%), Positives = 79/165 (47%), Gaps = 12/165 (7%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKA-----QEEHRTVEVEKVHLEKKLR 287
           Q    ++  +KM    E +   ++ L + +ER+ +      QEE    E +    EKK  
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550

Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEAL 347
           D+    ++E +R++E  +    E    +  EE++++  E +R+ E+++     W   E +
Sbjct: 551 DQEEKMREE-ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM-----WEQEEKM 604

Query: 348 QKWLQLTHEVEVQYYNIKKQN-AEKQLLVAKEGAEKIKKKRNTLF 391
           Q+  +   E E + +  ++++  ++Q  +  E  EK++++   ++
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 43/198 (21%), Positives = 93/198 (46%), Gaps = 17/198 (8%)

Query: 242 KKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL-RDEINLAKQEAQRL 300
           ++M +  E L   E+ +   +E++ + +E  R  E +    E+K+ R E  L +QE    
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE---- 289

Query: 301 KELREGTENERSRQKY--AEEELEQVREALRKAEKEL--ESHSSWYAPEALQKWLQLTHE 356
           KELRE  +  R ++K    EE++++  E + + E+++  +    W   E L  W Q   E
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL--WEQ---E 344

Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQAL 416
            +++    K ++ E+++    E  E++++K   +     +         + +I   ++ +
Sbjct: 345 KQMREQEQKMRDQEERMW---EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKM 401

Query: 417 SEVTAALRERLHRWQQIE 434
            E    +RE+  + Q+ E
Sbjct: 402 REEEETMREQEEKMQKQE 419



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 45/210 (21%), Positives = 92/210 (43%), Gaps = 19/210 (9%)

Query: 235 RYSKEHMK--KMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           R  +E M+  K M   E   R E+   + QE+    QEE    E      EKK+R+E  +
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQE-QEKKTWDQEEKMREEERMREREKKMREEEEM 575

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK---ELESHSSWYAPEALQK 349
            +++ ++++E  E    +  +    EE++++  E + + E+   E E        E +  
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM- 634

Query: 350 WLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKI 409
           W Q   E ++Q    K    E+++   +E  EK++++   + G         + + + K+
Sbjct: 635 WEQ---EEKMQEQEEKMWEQEEKM---REQEEKMREQEEKMQG-----QEEKMREQEEKM 683

Query: 410 LTAKQALSEVTAALRERLHR-WQQIEILCG 438
              ++ + E    +R +  + W Q E + G
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 20/119 (16%), Positives = 56/119 (47%), Gaps = 9/119 (7%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           +  + +E   KM +  E +   E+ + + +E++ + +E+ R         E+K+R++   
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-------EQEEKMREQEEK 668

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQK 349
            + + ++++E  E  + +  + +  EE++    E +   E+++  +    W   E  +K
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK 727



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 20/110 (18%), Positives = 53/110 (48%), Gaps = 10/110 (9%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           E  +KM +  E +   E+ + + +E++ + +E+ +  E +    E+K++ +    +++ +
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695

Query: 299 RLKELRE----------GTENERSRQKYAEEELEQVREALRKAEKELESH 338
           +++   E          G E +   Q+   E+ E++R+   K ++ L  H
Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745



 Score = 33.5 bits (75), Expect = 0.67
 Identities = 43/216 (19%), Positives = 98/216 (45%), Gaps = 24/216 (11%)

Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV--HLEKKLRD---- 288
           R  +E M+K  +++      E     L E+  K  E+ +  E E+     E+K+RD    
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468

Query: 289 ---EINLAKQEAQRLKELREGTENERSRQKYA-----EEELEQVREALRKAEKEL-ESHS 339
              E  + +QE  R +E +   + E+ R +       EE + +  E LR+ E+ + E   
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528

Query: 340 SWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHS 399
            W   E +++  + T E E + ++ +++  E++ +  +E  +K++++   +         
Sbjct: 529 MWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEERM--REREKKMREEEEMM-----REQE 580

Query: 400 SSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIE 434
             + + + K+   ++ + E    ++E+  + W+Q E
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 18/181 (9%)

Query: 237  SKEHMKKMMKDLEGLHR--------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRD 288
            S E  KK+  DLE   R        A++S+ D++    +  E+ +  E E  +L+ K+ D
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102

Query: 289  EINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ 348
            E  L  Q  +++KEL       ++R +  EEE+E  R +  KAEK+  S  S    E  +
Sbjct: 1103 EQALGIQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQ-RSDLSRELEEISE 1154

Query: 349  KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408
            +  +       Q    KK+ AE Q +  +   E+   +      T    H+ S+ ++  +
Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQKM--RRDLEEATLQHEATAATLRKKHADSVAELGEQ 1212

Query: 409  I 409
            I
Sbjct: 1213 I 1213



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 43/203 (21%), Positives = 91/203 (44%), Gaps = 23/203 (11%)

Query: 239  EHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            E + K+ K+ + L  A +Q+L DLQ      +++  T+   K+ LE+++ D     +QE 
Sbjct: 993  ETIAKLTKEKKALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1048

Query: 298  QRLKELREGTENERSRQKYAEE-------ELEQVREALRKAEKELESHSSWYAPEALQKW 350
            +   +L           K A+E       E +Q+ E L+K E E+ +  S    E   + 
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE---QA 1105

Query: 351  LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKIL 410
            L +  + +++    + +  E+++   +    K +K+R+ L        S  L+++  ++ 
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL--------SRELEEISERLE 1157

Query: 411  TAKQALSEVTAALRERLHRWQQI 433
             A  A S      ++R   +Q++
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKM 1180



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 27/143 (18%), Positives = 67/143 (46%), Gaps = 7/143 (4%)

Query: 233  QNRYSKEHMKKMMKDLEGLH-RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291
            +  +   +++  ++D + L  + ++ + +LQ R+ + +EE       +   EK+  D   
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147

Query: 292  LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351
              ++ ++RL+E    T  +    K  E E +++R  L +A  + E+ ++    +      
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVA 1207

Query: 352  QLTHEVEVQYYNIK--KQNAEKQ 372
            +L  +++    N++  KQ  EK+
Sbjct: 1208 ELGEQID----NLQRVKQKLEKE 1226



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 11/113 (9%)

Query: 274  TVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333
            T ++E+  L+++L +EI      A  L+  R   +  R + +  +E   +++ AL KA  
Sbjct: 1315 TQQIEE--LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANT 1372

Query: 334  ELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
            E+    + Y  +A+Q+    T E+E      KK+ A++ L  A+E  E +  K
Sbjct: 1373 EVAQWRTKYETDAIQR----TEELE----EAKKKLAQR-LQAAEEHVEAVNAK 1416



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 43/180 (23%), Positives = 78/180 (43%), Gaps = 38/180 (21%)

Query: 237  SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEV----EKVHLEKKLRDEIN 291
            S+    ++ K +EG L+  E  L+       +A   +R  +      ++HL+  LR + +
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672

Query: 292  LAKQEAQ----------RLKELREGTENERSRQKYAEEELEQVRE----------ALRKA 331
            L +Q A            ++ELR   E     +K AE+EL    E          +L   
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732

Query: 332  EKELESHSSWYAPEALQKWLQLTHEVE--VQYYNIKKQNAEKQLLVAKEGAEKIKKKRNT 389
            +K+LE+  S           Q+  E+E  +Q     ++ A+K +  A   AE++KK+++T
Sbjct: 1733 KKKLETDIS-----------QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDT 1781


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 18/181 (9%)

Query: 237  SKEHMKKMMKDLEGLHR--------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRD 288
            S E  KK+  DLE   R        A++S+ D++    +  E+ +  E E  +L+ K+ D
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102

Query: 289  EINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ 348
            E  L  Q  +++KEL       ++R +  EEE+E  R +  KAEK+  S  S    E  +
Sbjct: 1103 EQALGIQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQ-RSDLSRELEEISE 1154

Query: 349  KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408
            +  +       Q    KK+ AE Q +  +   E+   +      T    H+ S+ ++  +
Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQKM--RRDLEEATLQHEATAATLRKKHADSVAELGEQ 1212

Query: 409  I 409
            I
Sbjct: 1213 I 1213



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 43/203 (21%), Positives = 91/203 (44%), Gaps = 23/203 (11%)

Query: 239  EHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            E + K+ K+ + L  A +Q+L DLQ      +++  T+   K+ LE+++ D     +QE 
Sbjct: 993  ETIAKLTKEKKALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1048

Query: 298  QRLKELREGTENERSRQKYAEE-------ELEQVREALRKAEKELESHSSWYAPEALQKW 350
            +   +L           K A+E       E +Q+ E L+K E E+ +  S    E   + 
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE---QA 1105

Query: 351  LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKIL 410
            L +  + +++    + +  E+++   +    K +K+R+ L        S  L+++  ++ 
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL--------SRELEEISERLE 1157

Query: 411  TAKQALSEVTAALRERLHRWQQI 433
             A  A S      ++R   +Q++
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKM 1180



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 27/143 (18%), Positives = 67/143 (46%), Gaps = 7/143 (4%)

Query: 233  QNRYSKEHMKKMMKDLEGLH-RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291
            +  +   +++  ++D + L  + ++ + +LQ R+ + +EE       +   EK+  D   
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147

Query: 292  LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351
              ++ ++RL+E    T  +    K  E E +++R  L +A  + E+ ++    +      
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVA 1207

Query: 352  QLTHEVEVQYYNIK--KQNAEKQ 372
            +L  +++    N++  KQ  EK+
Sbjct: 1208 ELGEQID----NLQRVKQKLEKE 1226



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 11/113 (9%)

Query: 274  TVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333
            T ++E+  L+++L +EI      A  L+  R   +  R + +  +E   +++ AL KA  
Sbjct: 1315 TQQIEE--LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANT 1372

Query: 334  ELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
            E+    + Y  +A+Q+    T E+E      KK+ A++ L  A+E  E +  K
Sbjct: 1373 EVAQWRTKYETDAIQR----TEELE----EAKKKLAQR-LQAAEEHVEAVNAK 1416



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 43/180 (23%), Positives = 78/180 (43%), Gaps = 38/180 (21%)

Query: 237  SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEV----EKVHLEKKLRDEIN 291
            S+    ++ K +EG L+  E  L+       +A   +R  +      ++HL+  LR + +
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672

Query: 292  LAKQEAQ----------RLKELREGTENERSRQKYAEEELEQVRE----------ALRKA 331
            L +Q A            ++ELR   E     +K AE+EL    E          +L   
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732

Query: 332  EKELESHSSWYAPEALQKWLQLTHEVE--VQYYNIKKQNAEKQLLVAKEGAEKIKKKRNT 389
            +K+LE+  S           Q+  E+E  +Q     ++ A+K +  A   AE++KK+++T
Sbjct: 1733 KKKLETDIS-----------QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDT 1781


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 12/144 (8%)

Query: 239 EHMKKMMKDLEGLHRAE----QSLHDL----QERLHKAQEEHRTVEVEKVHLEKKLRDEI 290
           +H+++ ++ LEG  +++    Q+L  L    ++RL + +E  R  EV++V  +++L ++ 
Sbjct: 305 KHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQN 364

Query: 291 NLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQ 348
              +++ + L+E  E    +  R +  EE L +  E L+K EK L  +    W   E LQ
Sbjct: 365 ERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQ 424

Query: 349 KWLQLTHEVEVQYYNIKKQNAEKQ 372
           K  Q       Q + + KQ AE Q
Sbjct: 425 K--QEERLALSQNHKLDKQLAEPQ 446



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 1/129 (0%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL-RDEIN 291
           QN   +E  K + +  E L + EQ L   +ERL K +E  +  E      E++L + E  
Sbjct: 363 QNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEER 422

Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351
           L KQE +         + + +  + + E+L   +++  + E++++        E L+   
Sbjct: 423 LQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAAS 482

Query: 352 QLTHEVEVQ 360
           Q   ++E Q
Sbjct: 483 QQNQQLETQ 491



 Score = 36.6 bits (83), Expect = 0.079
 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 8/103 (7%)

Query: 237 SKEHMKKMMKDLEGLHRAEQSLHDLQERL----HKAQEEHRTVEVEKVHLEKKLRDEINL 292
           SKE  +++ +  E L   E      QERL     + +E+ +T++ +   L K+   E  L
Sbjct: 332 SKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQ---EQRL 388

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335
            KQE +RL++  E  + +  R    EE L +  E L+K E+ L
Sbjct: 389 RKQE-ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430


>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
          Length = 841

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 39/157 (24%), Positives = 78/157 (49%), Gaps = 21/157 (13%)

Query: 239 EHMKKMMKDLEGLHRAEQS----LHDLQERLHKAQEEHRTVEVEKVHLEKKLRD-EINLA 293
           E  K+  ++L G  R E++    L  LQ+ + + Q +  +++  K   E++L++ E +L 
Sbjct: 478 EDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQ 537

Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353
           +Q+ ++ + L++  E   +  K  EEEL+ VR+ L +A++E + H        L+    L
Sbjct: 538 QQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCH--------LKTISSL 589

Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
             EV        K   + Q ++ K+G+  +K  +  L
Sbjct: 590 KQEV--------KDTVDGQRILEKKGSAALKDLKRQL 618



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 46/203 (22%), Positives = 89/203 (43%), Gaps = 15/203 (7%)

Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAK 294
           R S E  K M+ +L      E+S H  +    + + E   + V +   E++LR+   L +
Sbjct: 423 RKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGV-RARYERELRE---LHE 478

Query: 295 QEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY------APEALQ 348
            + ++ +ELR     E++R +  E  L+Q  E L+     ++    W+      A E+LQ
Sbjct: 479 DKKRQEEELRGQIREEKARTRELET-LQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQ 537

Query: 349 KWLQLTHEVEVQ---YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDV 405
           +  Q   E   Q    +  + +  E++L   ++  E+ +++R+    T         D V
Sbjct: 538 QQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTV 597

Query: 406 DHKILTAKQALSEVTAALRERLH 428
           D + +  K+  S     L+ +LH
Sbjct: 598 DGQRILEKKG-SAALKDLKRQLH 619



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 33/172 (19%), Positives = 69/172 (40%), Gaps = 23/172 (13%)

Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291
           +Q R   +H  ++ +      + +Q L    + L + +++ +   +E     + L+D+++
Sbjct: 263 LQQRKEADHKAQLART----QKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVS 318

Query: 292 LAKQEAQRLKE--------LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYA 343
           +   +AQ   E        LR         Q    +EL  +RE       EL+   + Y 
Sbjct: 319 IQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYE 378

Query: 344 P---------EALQKWLQLTHEV--EVQYYNIKKQNAEKQLLVAKEGAEKIK 384
                       LQ+ L+    +  ++Q    +K+   ++L  A++ AEK K
Sbjct: 379 DLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRK 430


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 45/171 (26%), Positives = 78/171 (45%), Gaps = 16/171 (9%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           + +  K+   K M+++E   + E+    L+  L + +EE R  E+    L+KK  +E   
Sbjct: 620 EEKAKKKAAAKKMEEVEARRKQEEEARRLRW-LQQEEEERRHQEL----LQKKKEEEQER 674

Query: 293 AKQ--EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ-- 348
            ++  EA+RL E RE    E+ R++    E E+  +  R+ E++L         E LQ  
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734

Query: 349 -------KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392
                  K L+L  E   +    KK+  E+Q L  ++  E+ +KK     G
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 785



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 34/151 (22%), Positives = 68/151 (45%), Gaps = 13/151 (8%)

Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291
           ++ +   E +++   + +   R E+     +ERL K  +    VE  K   +K++  +  
Sbjct: 545 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 604

Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351
              ++ ++ KE  E    E++++K A +++E+V EA RK E+E              +WL
Sbjct: 605 QIDEKTEKAKE--ERLAEEKAKKKAAAKKMEEV-EARRKQEEEARR----------LRWL 651

Query: 352 QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEK 382
           Q   E       ++K+  E+Q  + K    K
Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAK 682



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 36/129 (27%), Positives = 63/129 (48%), Gaps = 6/129 (4%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQE--EHRTVEVEKVHLEKKLRDEINLAKQ 295
           +E  +++ K  E    AEQ   + +E+  + QE  E    E E+   E++L ++    +Q
Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 728

Query: 296 EA-QRLKELREGTENERSRQKYAEEELEQVR---EALRKAEKELESHSSWYAPEALQKWL 351
           E  Q  +EL+E  +  R +++  + ELE+ +   E  R AE++L+      A EA     
Sbjct: 729 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788

Query: 352 QLTHEVEVQ 360
            L   V+VQ
Sbjct: 789 ALNVTVDVQ 797



 Score = 36.6 bits (83), Expect = 0.079
 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 14/104 (13%)

Query: 285 KLRDEINLAKQEAQRLKELREGTENER-SRQKYAEEELEQVREALRKAEKELESHSSWYA 343
           ++  + +  ++E QRL+ LR   E E+  RQK  E++  ++ E   K E           
Sbjct: 527 RMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE----------- 575

Query: 344 PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387
            E L+K LQ    VE Q    KK+  E++     E  EK K++R
Sbjct: 576 -ERLRKVLQARERVE-QMKEEKKKQIEQKFAQIDEKTEKAKEER 617



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 16/119 (13%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDL----QERLHKAQ--------EEHRTVEVEKV 280
           Q R  K    K + +     R EQ   +     QER  + +        E+ R  E E++
Sbjct: 672 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 731

Query: 281 HLEKKLRDE---INLAKQEAQR-LKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335
             E++L++    + L K++ QR L+E ++  E +R  ++  +EE E+  +    A K L
Sbjct: 732 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 790


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 45/171 (26%), Positives = 78/171 (45%), Gaps = 16/171 (9%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           + +  K+   K M+++E   + E+    L+  L + +EE R  E+    L+KK  +E   
Sbjct: 616 EEKAKKKAAAKKMEEVEARRKQEEEARRLRW-LQQEEEERRHQEL----LQKKKEEEQER 670

Query: 293 AKQ--EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ-- 348
            ++  EA+RL E RE    E+ R++    E E+  +  R+ E++L         E LQ  
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730

Query: 349 -------KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392
                  K L+L  E   +    KK+  E+Q L  ++  E+ +KK     G
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 781



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 34/151 (22%), Positives = 68/151 (45%), Gaps = 13/151 (8%)

Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291
           ++ +   E +++   + +   R E+     +ERL K  +    VE  K   +K++  +  
Sbjct: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 600

Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351
              ++ ++ KE  E    E++++K A +++E+V EA RK E+E              +WL
Sbjct: 601 QIDEKTEKAKE--ERLAEEKAKKKAAAKKMEEV-EARRKQEEEARR----------LRWL 647

Query: 352 QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEK 382
           Q   E       ++K+  E+Q  + K    K
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAK 678



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 36/129 (27%), Positives = 63/129 (48%), Gaps = 6/129 (4%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQE--EHRTVEVEKVHLEKKLRDEINLAKQ 295
           +E  +++ K  E    AEQ   + +E+  + QE  E    E E+   E++L ++    +Q
Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724

Query: 296 EA-QRLKELREGTENERSRQKYAEEELEQVR---EALRKAEKELESHSSWYAPEALQKWL 351
           E  Q  +EL+E  +  R +++  + ELE+ +   E  R AE++L+      A EA     
Sbjct: 725 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784

Query: 352 QLTHEVEVQ 360
            L   V+VQ
Sbjct: 785 ALNVTVDVQ 793



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 14/131 (10%)

Query: 258 LHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENER-SRQKY 316
           LH +Q              V K  +++     ++  ++E QRL+ LR   E E+  RQK 
Sbjct: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV 555

Query: 317 AEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVA 376
            E++  ++ E   K E            E L+K LQ    VE Q    KK+  E++    
Sbjct: 556 EEDKRRRLEEVKLKRE------------ERLRKVLQARERVE-QMKEEKKKQIEQKFAQI 602

Query: 377 KEGAEKIKKKR 387
            E  EK K++R
Sbjct: 603 DEKTEKAKEER 613



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 16/119 (13%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDL----QERLHKAQ--------EEHRTVEVEKV 280
           Q R  K    K + +     R EQ   +     QER  + +        E+ R  E E++
Sbjct: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 727

Query: 281 HLEKKLRDE---INLAKQEAQR-LKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335
             E++L++    + L K++ QR L+E ++  E +R  ++  +EE E+  +    A K L
Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 16/137 (11%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           E  +K  + L  L RAEQ   + +ER  + QE  R +E+EK  LEK+   E    ++E +
Sbjct: 374 EQQRKEQERLAQLERAEQ---ERKERERQEQERKRQLELEK-QLEKQRELE---RQREEE 426

Query: 299 RLKEL--REGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
           R KE+  RE  + E  RQ+  E E  + +E L +  KE E          + K  + T E
Sbjct: 427 RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQED-------IVVLKAKKKTLE 479

Query: 357 VEVQYYNIKKQNAEKQL 373
            E++  N KK   E +L
Sbjct: 480 FELEALNDKKHQLEGKL 496



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 48/203 (23%), Positives = 87/203 (42%), Gaps = 25/203 (12%)

Query: 255 EQSLHDLQERLHKA------QEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKEL----- 303
           E  L D Q++L K        ++    E   + LEK+ +  +   ++E +RL +L     
Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQ 391

Query: 304 ----REGTENERSRQKYAEEELEQVREALRKAE----KELESHSSWYAPEALQKWLQLTH 355
               RE  E ER RQ   E++LE+ RE  R+ E    KE+E   +  A   L++  QL  
Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREA--AKRELERQRQLEW 449

Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415
           E   +   + ++N E++ +V  +  +K  +                L D+  ++ T +Q 
Sbjct: 450 ERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQE 509

Query: 416 LSEVTAA----LRERLHRWQQIE 434
           +     +    + E  H  QQ++
Sbjct: 510 IESTNKSRELRIAEITHLQQQLQ 532



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 24/93 (25%), Positives = 54/93 (58%), Gaps = 8/93 (8%)

Query: 245 MKDLEGLHRAEQSLHDLQ---ERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK 301
           +K+L  +H  +Q         ERL + ++E + +E+EK   E + R +    +++ Q L+
Sbjct: 607 LKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQ----ERDKQWLE 662

Query: 302 ELREGTENERSRQKYAEEELEQVREALRKAEKE 334
            +++  E++R R+ + EE+L++  E+++K + E
Sbjct: 663 HVQQEDEHQRPRKLHEEEKLKR-EESVKKKDGE 694



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 15/172 (8%)

Query: 238 KEHMKKMMKDLE--GLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295
           K+ +   +K ++   LHR   SL  L+  L   +   + +  +   +EK+ R ++     
Sbjct: 545 KQILNDQLKQVQQNSLHR--DSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDI 602

Query: 296 EAQRLKELRE-GTENERSRQKYAEEELEQVREALRK---AEKELESHSSWYAPEALQKWL 351
              +LKELRE   + +  +QK  E E  + +E  RK    EK+ E  +   A E  ++WL
Sbjct: 603 FNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKE-EAQRRAQERDKQWL 661

Query: 352 QLTHEVEVQYYNIKKQNAEKQL-----LVAKEGAEKIKKKRNTLFGTFHVAH 398
           +   + E ++   +K + E++L     +  K+G EK K++     G     H
Sbjct: 662 EHVQQ-EDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH 712


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 16/137 (11%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           E  +K  + L  L RAEQ   + +ER  + QE  R +E+EK  LEK+   E    ++E +
Sbjct: 374 EQQRKEQERLAQLERAEQ---ERKERERQEQERKRQLELEK-QLEKQRELE---RQREEE 426

Query: 299 RLKEL--REGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
           R KE+  RE  + E  RQ+  E E  + +E L +  KE E          + K  + T E
Sbjct: 427 RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQED-------IVVLKAKKKTLE 479

Query: 357 VEVQYYNIKKQNAEKQL 373
            E++  N KK   E +L
Sbjct: 480 FELEALNDKKHQLEGKL 496



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 48/203 (23%), Positives = 87/203 (42%), Gaps = 25/203 (12%)

Query: 255 EQSLHDLQERLHKA------QEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKEL----- 303
           E  L D Q++L K        ++    E   + LEK+ +  +   ++E +RL +L     
Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQ 391

Query: 304 ----REGTENERSRQKYAEEELEQVREALRKAE----KELESHSSWYAPEALQKWLQLTH 355
               RE  E ER RQ   E++LE+ RE  R+ E    KE+E   +  A   L++  QL  
Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREA--AKRELERQRQLEW 449

Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415
           E   +   + ++N E++ +V  +  +K  +                L D+  ++ T +Q 
Sbjct: 450 ERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQE 509

Query: 416 LSEVTAA----LRERLHRWQQIE 434
           +     +    + E  H  QQ++
Sbjct: 510 IESTNKSRELRIAEITHLQQQLQ 532



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 24/93 (25%), Positives = 54/93 (58%), Gaps = 8/93 (8%)

Query: 245 MKDLEGLHRAEQSLHDLQ---ERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK 301
           +K+L  +H  +Q         ERL + ++E + +E+EK   E + R +    +++ Q L+
Sbjct: 607 LKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQ----ERDKQWLE 662

Query: 302 ELREGTENERSRQKYAEEELEQVREALRKAEKE 334
            +++  E++R R+ + EE+L++  E+++K + E
Sbjct: 663 HVQQEDEHQRPRKLHEEEKLKR-EESVKKKDGE 694



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 15/172 (8%)

Query: 238 KEHMKKMMKDLE--GLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295
           K+ +   +K ++   LHR   SL  L+  L   +   + +  +   +EK+ R ++     
Sbjct: 545 KQILNDQLKQVQQNSLHR--DSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDI 602

Query: 296 EAQRLKELRE-GTENERSRQKYAEEELEQVREALRK---AEKELESHSSWYAPEALQKWL 351
              +LKELRE   + +  +QK  E E  + +E  RK    EK+ E  +   A E  ++WL
Sbjct: 603 FNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKE-EAQRRAQERDKQWL 661

Query: 352 QLTHEVEVQYYNIKKQNAEKQL-----LVAKEGAEKIKKKRNTLFGTFHVAH 398
           +   + E ++   +K + E++L     +  K+G EK K++     G     H
Sbjct: 662 EHVQQ-EDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH 712


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 47/181 (25%), Positives = 79/181 (43%), Gaps = 18/181 (9%)

Query: 237  SKEHMKKMMKDLEGLHR--------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRD 288
            S E  KK+  DLE   R        A++S  D++    +  E+ +  E E   L+ K+ D
Sbjct: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100

Query: 289  EINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ 348
            E  L  Q  +++KEL       ++R +  EEE+E  R +  KAEK+  S  S    E  +
Sbjct: 1101 EQALGMQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQ-RSDLSRELEEISE 1152

Query: 349  KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408
            +  +       Q    KK+ AE Q +  +   E+   +      T    H+ S+ ++  +
Sbjct: 1153 RLEEAGGATSAQIEMNKKREAEFQKM--RRDLEEATLQHEATAATLRKKHADSVAELGEQ 1210

Query: 409  I 409
            I
Sbjct: 1211 I 1211



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 37/162 (22%), Positives = 80/162 (49%), Gaps = 31/162 (19%)

Query: 240  HMKKMMKDLEGLHRAEQSLHDLQERLHKAQE-------------EHRTVEVE-KVHLEKK 285
            H+++M K+LE      Q++ DLQ RL +A++             E R  E+E +V  E+K
Sbjct: 1782 HLERMKKNLE------QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1835

Query: 286  LRDE-INLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAP 344
               E +   ++  +++KEL   TE +R      ++ +++++  ++  +++ E  +   + 
Sbjct: 1836 RNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE-EAEEQSN 1894

Query: 345  EALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
              L K+ ++ HE+E          AE++  +A+    K++ K
Sbjct: 1895 VNLSKFRRIQHELE---------EAEERADIAESQVNKLRVK 1927



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 42/203 (20%), Positives = 90/203 (44%), Gaps = 23/203 (11%)

Query: 239  EHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
            E + K+ K+ + L  A +Q+L DLQ      +++  T+   K+ LE+++ D     +QE 
Sbjct: 991  ETIAKLTKEKKALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1046

Query: 298  QRLKELREGTENERSRQKYAEE-------ELEQVREALRKAEKELESHSSWYAPEALQKW 350
            +   +L           K A+E       + +Q+ E L+K E E+    S    E   + 
Sbjct: 1047 KIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE---QA 1103

Query: 351  LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKIL 410
            L +  + +++    + +  E+++   +    K +K+R+ L        S  L+++  ++ 
Sbjct: 1104 LGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL--------SRELEEISERLE 1155

Query: 411  TAKQALSEVTAALRERLHRWQQI 433
             A  A S      ++R   +Q++
Sbjct: 1156 EAGGATSAQIEMNKKREAEFQKM 1178



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 48/210 (22%), Positives = 91/210 (43%), Gaps = 46/210 (21%)

Query: 237  SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEV----EKVHLEKKLRDEIN 291
            S+    ++ K +EG L+  E  L+       +A   +R  +      ++HL+  LR + +
Sbjct: 1611 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQED 1670

Query: 292  LAKQEAQ----------RLKELREGTENERSRQKYAEEELEQVRE----------ALRKA 331
            L +Q A            ++ELR   E     +K AE+EL    E          +L   
Sbjct: 1671 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1730

Query: 332  EKELESHSSWYAPEALQKWLQLTHEVE--VQYYNIKKQNAEKQLLVAKEGAEKIKKKRNT 389
            +K+LE+  S           Q+  E+E  +Q     ++ A+K +  A   AE++KK+++T
Sbjct: 1731 KKKLETDIS-----------QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDT 1779

Query: 390  LFGTFHVAH-----SSSLDDVDHKILTAKQ 414
               + H+         ++ D+ H++  A+Q
Sbjct: 1780 ---SAHLERMKKNLEQTVKDLQHRLDEAEQ 1806



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 43/185 (23%), Positives = 83/185 (44%), Gaps = 26/185 (14%)

Query: 241  MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL------RDEINLAK 294
            +K ++K  E     E+ + +++E   K +EE    E ++  LE+K+      ++++ L  
Sbjct: 840  IKPLLKSAE----TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895

Query: 295  Q-EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353
            Q EA  L +  E  +     +   E ++++V E   +AE E E ++   A +        
Sbjct: 896  QAEADSLADAEERCDQLIKTKIQLEAKIKEVTE---RAEDEEEINAELTAKK-------- 944

Query: 354  THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAK 413
              ++E +   +KK   + +L +AK   EK   +      T  +A    LD+   K+   K
Sbjct: 945  -RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA---GLDETIAKLTKEK 1000

Query: 414  QALSE 418
            +AL E
Sbjct: 1001 KALQE 1005



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 17/147 (11%)

Query: 239  EHMKKMMKDLEGLH-----------RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLR 287
            E +KK   ++ GL            + ++ + +LQ R+ + +EE       +   EK+  
Sbjct: 1082 EKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141

Query: 288  DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEAL 347
            D     ++ ++RL+E    T  +    K  E E +++R  L +A  + E+ ++    +  
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201

Query: 348  QKWLQLTHEVEVQYYNIK--KQNAEKQ 372
                +L  +++    N++  KQ  EK+
Sbjct: 1202 DSVAELGEQID----NLQRVKQKLEKE 1224



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 11/113 (9%)

Query: 274  TVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333
            T ++E+  L+++L +EI      A  L+  R   +  R + +  +E   +++ A+ KA  
Sbjct: 1313 TQQIEE--LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS 1370

Query: 334  ELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386
            E+    + Y  +A+Q+    T E+E      KK+ A++ L  A+E  E +  K
Sbjct: 1371 EVAQWRTKYETDAIQR----TEELE----EAKKKLAQR-LQDAEEHVEAVNAK 1414



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 47/230 (20%), Positives = 92/230 (40%), Gaps = 46/230 (20%)

Query: 251  LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENE 310
            L R +Q+     E L +  EE    +    H  +  R + +L +++ +  +E +   +  
Sbjct: 1305 LSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRA 1364

Query: 311  RS---------RQKYAE------EELEQVREALRKAEKELESHSSWYAPE--ALQKWLQ- 352
             S         R KY        EELE+ ++ L +  ++ E H      +  +L+K  Q 
Sbjct: 1365 MSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQR 1424

Query: 353  LTHEVEVQYYNIKKQNAEKQLLVAK----------------------EGAEKIKKKRNTL 390
            L +EVE    ++++ NA    L  K                      E ++K  +  +T 
Sbjct: 1425 LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTE 1484

Query: 391  FGTFHVAHSSSLDDVD---HKILTAKQALSEVTAALRE---RLHRWQQIE 434
                  A+  SLD ++    +    +Q +S++T  + E   R+H  ++I+
Sbjct: 1485 LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1534


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 22/168 (13%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           E  +KM +  E +   E+ + +L+E++H+ QE+ R  E EK   E+K+R++    +QEA+
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQE-EKRQEEEKIREQEKRQEQEAK 431

Query: 299 RLKE---LREGTENERSRQK--YAEEEL----EQVREALRKAEKELESHSSWYAPEALQK 349
             ++   +RE  E  R ++K  + +EE     E++RE     EK  E    W   E + +
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE----EKRQEQEEMWRQEEKIHE 487

Query: 350 ----WLQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTLF 391
               W Q   ++  Q   I+KQ  +  +Q    +E  EKI+++   ++
Sbjct: 488 QEEIWRQ-KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 5/148 (3%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +  E +   E+ +   +E + + +E+ R  E      E+K+R +  +
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385

Query: 293 AKQEAQRLKELREGT-ENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKW 350
             ++ ++++EL E   E E+ R+   +EE  Q  E +R+ EK  E  +  W   E +++ 
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442

Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKE 378
            +   E E + +  +++  E++ +  +E
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEE 470



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 45/222 (20%), Positives = 95/222 (42%), Gaps = 25/222 (11%)

Query: 233 QNRYSKEHMKKMMKDLEGLH-----RAEQSLHDLQERLHKAQEEHRTVEV----EKVH-L 282
           Q    +E  KKM +  E +H     R E+   + +E   + ++ H   E+    EK+H  
Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501

Query: 283 EKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY 342
           E+K+R +     ++ ++++E  E    +  +    EE++ +  E  R+ EK  E    W 
Sbjct: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561

Query: 343 APEALQK----WLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAH 398
             +  ++    W Q   E +++    K    E+++   +E  EK +++   ++       
Sbjct: 562 EEKRQEQEDKMWRQ---EEKIREQEEKVWRQEEKI---REQEEKRQEQEEKMW-----KQ 610

Query: 399 SSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQ 440
              + + + KI   ++ + E    +RE+    Q+ E   G Q
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 47/226 (20%), Positives = 104/226 (46%), Gaps = 27/226 (11%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL-RDEIN 291
           Q     E  +K+ K  E + R E+ + + +E++ + QEE    + EK+  ++++ R+E  
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI-REQEEKMWRQEEKIREQEEMWREEEK 552

Query: 292 LAKQEAQRLKELREGTENERSRQ----KYAEEELEQVREALRKAE--KELESHSSWYAPE 345
           + +QE    +E R+  E++  RQ    +  EE++ +  E +R+ E  ++ +    W   E
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612

Query: 346 AL----QKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEG---------AEKIKKKRNTLFG 392
            +    +K  +   ++  Q   I++Q    Q    K G          EK++++  T++ 
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW- 671

Query: 393 TFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIEILC 437
                    + + + KI   ++ + E    ++E+  + W+Q E +C
Sbjct: 672 ----RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 44/206 (21%), Positives = 95/206 (46%), Gaps = 27/206 (13%)

Query: 244 MMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDEINLAKQEAQRLKE 302
           M +  E + R E+ + + +E++ + QEE    + EK+  LE+K+ ++  + +QE +R +E
Sbjct: 358 MWEKEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 416

Query: 303 LREGTENERSRQKYA-----EEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357
             +  E E+ +++ A     EE++ +  E +R+ EK++     W   E + +  ++  E 
Sbjct: 417 -EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM-----WRQEEKIHEQEKIREEE 470

Query: 358 EVQYYNIKKQNAEK---------QLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408
           + Q      +  EK         Q     E  EKI+K+   ++          + + + K
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW-----RQEEKIREQEEK 525

Query: 409 ILTAKQALSEVTAALRERLHRWQQIE 434
           I   ++ +      +RE+   W++ E
Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEE 551



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/161 (16%), Positives = 79/161 (49%), Gaps = 3/161 (1%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +K+ +  E +   E+   + +E++ K +E+ R  E +    E+K+R++   
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY--APEALQKW 350
            +++ +  +E  E    +  +    EE++++  E + + E+++           E +++ 
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694

Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391
            ++  E E + +  +++  E++  + +E  EK++++   ++
Sbjct: 695 EEMMQEQEEKMWEQEEKMCEQEEKM-QEQEEKMRRQEEKMW 734



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 36/196 (18%), Positives = 87/196 (44%), Gaps = 13/196 (6%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297
           +E   KM +  E +   E+ +   +E++ + +E+ +  E +    E+K+R++    +++ 
Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625

Query: 298 QRLKELREG-TENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
           ++++E  E   E E   Q+  E+  EQ  +   + EK  E   + +  E  +K  +   +
Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE--EKIREQEKK 683

Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQAL 416
           +  Q   I++Q    Q     E  EK+ ++   +           + + + K+   ++ +
Sbjct: 684 IREQEEKIREQEEMMQ-----EQEEKMWEQEEKM-----CEQEEKMQEQEEKMRRQEEKM 733

Query: 417 SEVTAALRERLHRWQQ 432
            E    LR++  + Q+
Sbjct: 734 WEQEVRLRQQEEKMQE 749



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 22/113 (19%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q   ++E  +KM +  E +   E+ + + +E + + +E+ R  E +    E+K+R++  +
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVRE-------ALRKAEKELESH 338
            +++ +++ E  E    +  + +  EE++ +  E        LR+ E++++ H
Sbjct: 698 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 29/151 (19%), Positives = 68/151 (45%), Gaps = 18/151 (11%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH---------------LE 283
           +H+ K ++ +    +A+   ++L  RL++ QEE    + EK+                 E
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327

Query: 284 KKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSW 341
           +K+R++    +++ + + E  E    +       EE++ +  E + + E+++  +    W
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387

Query: 342 YAPEALQKWLQLTHEVE-VQYYNIKKQNAEK 371
              E +++  +  HE E ++    K+Q  EK
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 11/157 (7%)

Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293
           +RY +E  K+       L+R   +  +L+E+  K QE+ + VE EK         EI L 
Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 243

Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353
            +E +R  E  +    ++  Q  A+   ++++    K + ++E +  W      Q+    
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303

Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
             E ++Q +  K Q  E+++   +E  EKI+++   +
Sbjct: 304 RQEEKIQEWEEKIQEQEEKI---REQEEKIREQEEKM 337



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 29/157 (18%), Positives = 64/157 (40%), Gaps = 26/157 (16%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL------ 286
           Q    +E  +KM K  E +   E+ + + +E++ + +E+ R  E      E+K+      
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655

Query: 287 ----------------RDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRK 330
                           R E  + +QE ++++E  E    +    +  EE++ +  E + +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQE-KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714

Query: 331 AEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQ 367
            E++++        +  + W Q   EV ++    K Q
Sbjct: 715 QEEKMQEQEEKMRRQEEKMWEQ---EVRLRQQEEKMQ 748


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 32/191 (16%), Positives = 93/191 (48%), Gaps = 12/191 (6%)

Query: 242 KKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK 301
           K+ M + E + + E+ +   +E++H  +E+ R  E +    E+K+R++    +++ ++++
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540

Query: 302 ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQY 361
           E  E  + +  +    EE++++  +  R+ EK  E        E +++  +   E E + 
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE------EKIREQKEKIREQEEKI 594

Query: 362 YNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTA 421
           +  +++  E++ ++ +E  EK+ ++   +           + + + K+   ++ + E   
Sbjct: 595 WEQEEKIREQEEMM-QEQEEKMWEQEEKM-----CEQEEKMQEQEEKMRRQEEKMWEQEV 648

Query: 422 ALRERLHRWQQ 432
            LR++  + Q+
Sbjct: 649 RLRQQEEKMQE 659



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 29/162 (17%), Positives = 83/162 (51%), Gaps = 8/162 (4%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +KM +  E +   E+ + + +E++ + +E  +  E +    E+K++++  +
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS--WYAPEALQKW 350
            +QE ++++E  E    ++ + +  EE++ +  E +R+ E+ ++      W   E  +K 
Sbjct: 567 RRQE-EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW---EQEEKM 622

Query: 351 LQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTL 390
            +   +++ Q   +++Q  +  +Q +  ++  EK+++ +  L
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/137 (20%), Positives = 69/137 (50%), Gaps = 4/137 (2%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV-HLEKKLRDEINLAKQEA 297
           +H+ K ++ +    +A+   ++L  RL++ QEE    + EK+   E+K++++    +++ 
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELE--SHSSWYAPEALQKWLQLTH 355
           ++++E  E    +       EE++ +  E + + E+++       W   E +++  +  H
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387

Query: 356 EVE-VQYYNIKKQNAEK 371
           E E ++    K+Q  EK
Sbjct: 388 EQEKIREQEEKRQEEEK 404



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 42/205 (20%), Positives = 96/205 (46%), Gaps = 16/205 (7%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298
           E  +KM +  E +   E+ +  L+E + + +E+ R +E EK+H ++K+R+      QE +
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-EKMHEQEKIRE------QEEK 398

Query: 299 RLKELREGTENERSRQK----YAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLT 354
           R +E +   + +R  Q+      EE++ +  E +R+ EK++         +   +  +  
Sbjct: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458

Query: 355 HEVEVQYYNIKKQNAEKQLLVAKE---GAEKIKKKRNTLFGTFHVAH--SSSLDDVDHKI 409
            E E  +   +K   ++++   KE     EKI+K+   ++      H     + + + K+
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518

Query: 410 LTAKQALSEVTAALRERLHRWQQIE 434
              ++ + E    +RE+  + ++ E
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQE 543



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 42/211 (19%), Positives = 103/211 (48%), Gaps = 17/211 (8%)

Query: 233 QNRYSKEHMKKMMKDLEG---LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDE 289
           + R  +E +++  K  E    + R E+ + + +E++ + QE+    + EK+H ++K+R+E
Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEKKMWRQEEKIHEQEKIREE 455

Query: 290 INLAKQEA--QRLKELREGTENERSRQK-YAEEELEQVREALRKAEKELESHSSWYAPEA 346
               +QE   ++ +++RE  E  R ++K + +E++ +  E + + E+++         + 
Sbjct: 456 EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE 515

Query: 347 LQKWLQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDD 404
            + W Q   ++  Q   I++Q  +  +Q  + +E  EK+ ++   +           +  
Sbjct: 516 EKMWRQ-EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM------QEQEKMRR 568

Query: 405 VDHKILTAKQALSEVTAALRERLHR-WQQIE 434
            + KI   ++ + E    +RE+  + W+Q E
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEE 599



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 46/232 (19%), Positives = 100/232 (43%), Gaps = 31/232 (13%)

Query: 234 NRYSKEHMKKMMKDLEGLHR-------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL 286
           NR +++  +KM +  E +          E+ + + +E++ + +E+ R  E      E+K+
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351

Query: 287 R--DEINLAKQEAQRLKE---------LREGTENERSRQKYAE-EELEQVREALRKAEKE 334
           R  +E+   K+E  R  E         +RE  E    ++K  E EE  Q  E +R+ EK 
Sbjct: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 411

Query: 335 LESHSS-WYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKE----------GAEKI 383
            E  +  W   E +++  +   E E + +  +++  E++ +  +E            EKI
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471

Query: 384 KKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIE 434
           +++         +     +   + K+   ++ + +    +RE+  + W+Q E
Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 11/157 (7%)

Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293
           +RY +E  K+       L+R   +  +L+E+  K QE+ + VE EK         EI L 
Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 243

Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353
            +E +R  E  +    ++  Q  A+   ++++    K + ++E +  W      Q+    
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303

Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390
             E ++Q +  K Q  E+++   +E  EKI+++   +
Sbjct: 304 RQEEKIQEWEEKIQEQEEKI---REQEEKIREQEEKM 337



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 17/99 (17%), Positives = 50/99 (50%)

Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292
           Q    +E  +K+ +  E +   E+ + + +E++ + +E  +  E +    E+K+ ++   
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628

Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKA 331
            +++ ++++   E    +  R +  EE++++ +E L  A
Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667


>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
          Length = 777

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 83/384 (21%), Positives = 148/384 (38%), Gaps = 60/384 (15%)

Query: 276 EVEKVHLEKKLRDEINLAKQEAQRLKELRE-GTENERSRQKYAEE---------ELEQVR 325
           +V K   EK     ++L ++  + +KE+++ G E  +S +K  EE          ++ + 
Sbjct: 74  DVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSIT 133

Query: 326 EALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIK- 384
           +AL+K+++    ++     E L+K      E+E      KK     +L V K    K   
Sbjct: 134 QALQKSKENY--NAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAKADF 191

Query: 385 KKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNN 444
           +++ T     H    +++ +   + L  K A S+ T   R  L  +++ +     + +  
Sbjct: 192 EQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGI-K 250

Query: 445 PGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLT 504
           P      A   I        +   A  +   D D ++   +  +  +  S++    Q  T
Sbjct: 251 PRKRKTFALPGI------IKKEKDAESVECPDADSLN---IPDVDEEGYSIKPETNQNDT 301

Query: 505 EPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVH 564
           +  H   S      SDS+S      + R+  KP             M  N SH  +  + 
Sbjct: 302 KENHFYSS------SDSDSEDEEPKKYRIEIKP-------------MHPNNSHHTMASLD 342

Query: 565 PGSL-VEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGG-------------SPH 610
              + +  +  SPA+++ + + +N  L     L +  PSAPP                P 
Sbjct: 343 ELKVSIGNITLSPAISRHSPVQMNRNLSN-EELTKSKPSAPPNEKGTSDLLAWDPLFGPS 401

Query: 611 LDSSRSH---SPSSPDPDTPSPVG 631
           LDSS S    S SS  P TP  VG
Sbjct: 402 LDSSSSSSLTSSSSARPTTPLSVG 425


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 84/397 (21%), Positives = 162/397 (40%), Gaps = 50/397 (12%)

Query: 52  DKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGE 111
           +K    SE+ K S E   ++ K ++D          + + L EDL     T+   T   E
Sbjct: 301 EKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLT---E 357

Query: 112 DKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTN 171
           +K   +E+  KA      +++ V E    + +  EL + E+  ++L+ +   +  L +  
Sbjct: 358 EKETQMEESNKA---RAAHSFVVTEFETTVCSLEELLRTEQ--QRLEKNEDQLKILTMEL 412

Query: 172 TTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAY 231
              +  + +MT  ++ ++++L+ L  VL     L   N  K F  +   + G        
Sbjct: 413 QKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYEN--KQFEKIAEELKGTEQELIGL 470

Query: 232 IQNRY---------------SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHR-- 273
           +Q R                S+++  K +KDL+  L   +    +L    +K   E++  
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKEL 530

Query: 274 TVEVEKVHLEKKLRDEI--NLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKA 331
           T E   + LE K + E   N  KQE + LK++    EN +  +     ELE VRE L++ 
Sbjct: 531 TQETSDMTLELKNQQEDINNNKKQEERMLKQI----ENLQETETQLRNELEYVREELKQK 586

Query: 332 EKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAK-EGAEKIKKKRNTL 390
             E++                   + E    N++KQ   K   + + +   K  KK+ T 
Sbjct: 587 RDEVKCK---------------LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTA 631

Query: 391 FGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERL 427
                  +   ++ ++ ++ +AKQ   E+T   ++ +
Sbjct: 632 ESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEI 668



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 34/144 (23%), Positives = 71/144 (49%), Gaps = 6/144 (4%)

Query: 251 LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENE 310
           +++ E  L   +++  +  + ++    +K   E+ L +E+  AK  A    +L++  + +
Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEID-K 701

Query: 311 RSRQKYAEEE--LEQVREALRKAEKELESHSSWY-APEALQKWLQLTHEVEVQYYNIKKQ 367
           R + K AE    +E+ +    K  +E +S    Y + E  Q  L+ + E+E+     +  
Sbjct: 702 RCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELL 761

Query: 368 NAEKQLLVAKEGAEKIKK--KRNT 389
           + +KQL + +E  EK+K+  K NT
Sbjct: 762 SVKKQLEIEREEKEKLKREAKENT 785



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 50/227 (22%), Positives = 92/227 (40%), Gaps = 46/227 (20%)

Query: 245 MKDLEGL-HRAEQSLHDLQERLHKAQEEHRTVEVEKVH------------------LEKK 285
           MKDL  L   +   ++ L+E+  K Q E+    +EK H                   +K 
Sbjct: 282 MKDLTFLLEESRDKVNQLEEKT-KLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKA 340

Query: 286 LRDEINLAKQEAQRLKELREGTENERSRQKYA--------EEELEQVREALRKAEKELES 337
           L +++ +A +   +L E +E    E ++ + A        E  +  + E LR  ++ LE 
Sbjct: 341 LEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK 400

Query: 338 HSSWY---------APEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEG-----AEKI 383
           +                 L++  +LT+  EV+   +KK   EK+ L+ +       AE++
Sbjct: 401 NEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEEL 460

Query: 384 KKKRNTLFGTFHVAHSSSLDDVDHK---ILTAKQALSEVTAALRERL 427
           K     L G    A    + D++ +   I T++Q  S+    L+  L
Sbjct: 461 KGTEQELIGLLQ-AREKEVHDLEIQLTAITTSEQYYSKEVKDLKTEL 506



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 12/96 (12%)

Query: 295 QEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLT 354
           +EA+++K+ +  TE E  +++   +E  ++ EA RKA +EL+     +  E +   L+L 
Sbjct: 111 KEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQ-----FGNEKVS--LKLE 163

Query: 355 HEVEVQYYNIKKQNAEKQLL-----VAKEGAEKIKK 385
             ++     IK+ NA + L           AEK KK
Sbjct: 164 EGIQENKDLIKENNATRHLCNLLKETCARSAEKTKK 199



 Score = 29.6 bits (65), Expect = 9.7
 Identities = 35/155 (22%), Positives = 67/155 (43%), Gaps = 23/155 (14%)

Query: 246 KDLEGLHRAEQSLHDL-QERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304
           KDL   + A + L +L +E   ++ E+ +  E E+    +   D  N  ++     +ELR
Sbjct: 170 KDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELR 229

Query: 305 EGTENERSRQKY-AEEELEQVREALRKAEKELESHS--------------------SWYA 343
              EN R    +  +E+ E+++   ++ +KE+                        ++  
Sbjct: 230 VQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLL 289

Query: 344 PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKE 378
            E+  K  QL  + ++Q  N+ KQ+ EKQ  + KE
Sbjct: 290 EESRDKVNQLEEKTKLQSENL-KQSIEKQHHLTKE 323


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 37/152 (24%), Positives = 77/152 (50%), Gaps = 9/152 (5%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEI-NLAKQEA 297
           E +KK++ + +G  ++ + L  L+  L K   + +TV+  K  + K L++EI N+  ++A
Sbjct: 797 EELKKVIHEKDGKIKSVEEL--LEAELLKVANKEKTVQDLKQEI-KALKEEIGNVQLEKA 853

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357
           Q+L  +    +  ++  K  EE++  ++  L + EK+L +   W      +      H  
Sbjct: 854 QQLS-ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912

Query: 358 EVQYYNIKKQNAEKQL----LVAKEGAEKIKK 385
           EV  +N+K+ ++  Q     +V KE   ++K+
Sbjct: 913 EVAQHNLKEASSASQFEELEIVLKEKENELKR 944



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 24/181 (13%)

Query: 239  EHMKKMMKDLEG-LHRAEQSLHDLQERLH-KAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296
            E  K ++ + EG L + ++S+   + +   K  E H+T+        K+++     ++QE
Sbjct: 1137 EKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQE 1188

Query: 297  AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
             +RL+   +  EN R  +++ E ELE       KAE E  ++ +    E      +L  +
Sbjct: 1189 LERLRSENKDIENLRREREHLEMELE-------KAEMERSTYVT-EVRELKDLLTELQKK 1240

Query: 357  VEVQYYNIKKQNAEKQLLVAK--EGAEKIKKKRN---TLFGTFHVAHSSSLDDVDHKILT 411
            ++  Y    +QN E  LL A+  E   K++ ++N    + G  H A   SL+ +  KI+ 
Sbjct: 1241 LDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKA-QQSLELIQSKIVK 1299

Query: 412  A 412
            A
Sbjct: 1300 A 1300



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 22/192 (11%)

Query: 245 MKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304
           MKD  G    E ++   Q ++H + +E + ++++   + +++  EI   KQE   L++  
Sbjct: 376 MKDRIGTLEKEHNV--FQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAV 433

Query: 305 EGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK--WLQLTHEVEVQYY 362
             T N+   ++ A  EL ++R+   +   EL   +     E +QK    Q   +++VQ  
Sbjct: 434 SNTTNQLESKQSA--ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQ 491

Query: 363 NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAA 422
             +++  E Q  + K  AE                H ++  D+  K +  +  +  + + 
Sbjct: 492 EAERRWEEVQSYIRKRTAE----------------HEAAQQDLQSKFVAKENEVQSLHSK 535

Query: 423 LRERLHRWQQIE 434
           L + L   QQ+E
Sbjct: 536 LTDTLVSKQQLE 547



 Score = 29.6 bits (65), Expect = 9.7
 Identities = 18/75 (24%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 251  LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA---KQEAQRLKELREGT 307
            LH+A+QSL  +Q ++ KA  +   +E   V  E +  ++  ++    Q   +L++L +  
Sbjct: 1283 LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAV 1342

Query: 308  ENERSRQKYAEEELE 322
              + +++K   + LE
Sbjct: 1343 NQQLTKEKEHYQVLE 1357


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 37/152 (24%), Positives = 77/152 (50%), Gaps = 9/152 (5%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEI-NLAKQEA 297
           E +KK++ + +G  ++ + L  L+  L K   + +TV+  K  + K L++EI N+  ++A
Sbjct: 797 EELKKVIHEKDGKIKSVEEL--LEAELLKVANKEKTVQDLKQEI-KALKEEIGNVQLEKA 853

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357
           Q+L  +    +  ++  K  EE++  ++  L + EK+L +   W      +      H  
Sbjct: 854 QQLS-ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912

Query: 358 EVQYYNIKKQNAEKQL----LVAKEGAEKIKK 385
           EV  +N+K+ ++  Q     +V KE   ++K+
Sbjct: 913 EVAQHNLKEASSASQFEELEIVLKEKENELKR 944



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 22/192 (11%)

Query: 245 MKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304
           MKD  G    E ++   Q ++H + +E + ++++   + +++  EI   KQE   L++  
Sbjct: 376 MKDRIGTLEKEHNV--FQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAV 433

Query: 305 EGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK--WLQLTHEVEVQYY 362
             T N+   ++ A  EL ++R+   +   EL   +     E +QK    Q   +++VQ  
Sbjct: 434 SNTTNQLESKQSA--ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQ 491

Query: 363 NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAA 422
             +++  E Q  + K  AE                H ++  D+  K +  +  +  + + 
Sbjct: 492 EAERRWEEVQSYIRKRTAE----------------HEAAQQDLQSKFVAKENEVQSLHSK 535

Query: 423 LRERLHRWQQIE 434
           L + L   QQ+E
Sbjct: 536 LTDTLVSKQQLE 547



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 46/212 (21%), Positives = 87/212 (41%), Gaps = 35/212 (16%)

Query: 239  EHMKKMMKDLEG-LHRAEQSLHDLQERLH-KAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296
            E  K ++ + EG L + ++S+   + +   K  E H+T+        K+++     ++QE
Sbjct: 1108 EKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQE 1159

Query: 297  AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
             +RL+   +  EN R  +++ E ELE       KAE E     S Y  E  +   QL   
Sbjct: 1160 LERLRSENKDIENLRREREHLEMELE-------KAEME----RSTYVTEVRELKAQLNET 1208

Query: 357  V-EVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLD------------ 403
            + +++    ++Q     L  A++  E I+ K     G   V  +S +             
Sbjct: 1209 LTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMS 1268

Query: 404  -DVDHKILTAKQALSEVTAALRERLHRWQQIE 434
              ++  +   +Q L  V   L +    +Q +E
Sbjct: 1269 VSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE 1300


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 37/152 (24%), Positives = 77/152 (50%), Gaps = 9/152 (5%)

Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEI-NLAKQEA 297
           E +KK++ + +G  ++ + L  L+  L K   + +TV+  K  + K L++EI N+  ++A
Sbjct: 797 EELKKVIHEKDGKIKSVEEL--LEAELLKVANKEKTVQDLKQEI-KALKEEIGNVQLEKA 853

Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357
           Q+L  +    +  ++  K  EE++  ++  L + EK+L +   W      +      H  
Sbjct: 854 QQLS-ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912

Query: 358 EVQYYNIKKQNAEKQL----LVAKEGAEKIKK 385
           EV  +N+K+ ++  Q     +V KE   ++K+
Sbjct: 913 EVAQHNLKEASSASQFEELEIVLKEKENELKR 944



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 24/181 (13%)

Query: 239  EHMKKMMKDLEG-LHRAEQSLHDLQERLH-KAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296
            E  K ++ + EG L + ++S+   + +   K  E H+T+        K+++     ++QE
Sbjct: 1137 EKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQE 1188

Query: 297  AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356
             +RL+   +  EN R  +++ E ELE       KAE E  ++ +    E      +L  +
Sbjct: 1189 LERLRSENKDIENLRREREHLEMELE-------KAEMERSTYVT-EVRELKDLLTELQKK 1240

Query: 357  VEVQYYNIKKQNAEKQLLVAK--EGAEKIKKKRN---TLFGTFHVAHSSSLDDVDHKILT 411
            ++  Y    +QN E  LL A+  E   K++ ++N    + G  H A   SL+ +  KI+ 
Sbjct: 1241 LDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKA-QQSLELIQSKIVK 1299

Query: 412  A 412
            A
Sbjct: 1300 A 1300



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 22/192 (11%)

Query: 245 MKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304
           MKD  G    E ++   Q ++H + +E + ++++   + +++  EI   KQE   L++  
Sbjct: 376 MKDRIGTLEKEHNV--FQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAV 433

Query: 305 EGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK--WLQLTHEVEVQYY 362
             T N+   ++ A  EL ++R+   +   EL   +     E +QK    Q   +++VQ  
Sbjct: 434 SNTTNQLESKQSA--ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQ 491

Query: 363 NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAA 422
             +++  E Q  + K  AE                H ++  D+  K +  +  +  + + 
Sbjct: 492 EAERRWEEVQSYIRKRTAE----------------HEAAQQDLQSKFVAKENEVQSLHSK 535

Query: 423 LRERLHRWQQIE 434
           L + L   QQ+E
Sbjct: 536 LTDTLVSKQQLE 547



 Score = 29.6 bits (65), Expect = 9.7
 Identities = 18/75 (24%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 251  LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA---KQEAQRLKELREGT 307
            LH+A+QSL  +Q ++ KA  +   +E   V  E +  ++  ++    Q   +L++L +  
Sbjct: 1283 LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAV 1342

Query: 308  ENERSRQKYAEEELE 322
              + +++K   + LE
Sbjct: 1343 NQQLTKEKEHYQVLE 1357


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 9/129 (6%)

Query: 262 QERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEEL 321
           Q RL K QEE   VE E+   + +L  E    K E +RL+   E  + E  R++  EE+ 
Sbjct: 410 QARLQKEQEEQERVEKEE---QDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKK 466

Query: 322 EQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAE 381
           +Q  E  RKA +E +  +     E L K  Q   + E      +K+ AE +   A+E AE
Sbjct: 467 KQEGEEKRKAGEEAKRKAE---EELLLKEKQEQEKQEKAMIEKQKEAAETK---AREVAE 520

Query: 382 KIKKKRNTL 390
           +++ +R  +
Sbjct: 521 QMRLEREQI 529



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 38/160 (23%), Positives = 79/160 (49%), Gaps = 14/160 (8%)

Query: 276 EVEKVHLEKKLRDEINLAKQEAQRL-KELREGTENERSRQKYAEEELEQVREALRKAEKE 334
           E  K+  EK+ +  +   ++E +R+ KE ++  E E  ++K AEEE  ++ E  RK E+E
Sbjct: 399 EAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRK-AEEERLRLEEEARKQEEE 457

Query: 335 LESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTF 394
            +        +  ++  +   E         K+ AE++LL+ KE  E+ K+++  +    
Sbjct: 458 RKRQEEEKKKQEGEEKRKAGEEA--------KRKAEEELLL-KEKQEQEKQEKAMIEKQK 508

Query: 395 HVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIE 434
             A + + +  +   L  +Q + ++    +ERL R ++I+
Sbjct: 509 EAAETKAREVAEQMRLEREQIMLQIE---QERLERKKRID 545



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 16/104 (15%)

Query: 260 DLQERLHKAQEEHRT---VEVEKVHLEKKLRDEINLAKQEAQRLKELREGTE-------- 308
           D ++RL K + E R       E+  LEK+ R  +   KQ  +R ++L E  +        
Sbjct: 52  DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAA 111

Query: 309 -NERSRQKYAEEE--LE-QVREALRKAEK-ELESHSSWYAPEAL 347
             E+ +QK  EEE  LE  +R +L + ++ EL+   SW AP A+
Sbjct: 112 VEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAI 155



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 29/143 (20%), Positives = 59/143 (41%), Gaps = 7/143 (4%)

Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLR---DEINLAK 294
           +E  +   ++ + L R E      +ERL   +E  +  E  K   E+K +   +E   A 
Sbjct: 418 EEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG 477

Query: 295 QEAQRLKE----LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKW 350
           +EA+R  E    L+E  E E+  +   E++ E      R+  +++         +  Q+ 
Sbjct: 478 EEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQER 537

Query: 351 LQLTHEVEVQYYNIKKQNAEKQL 373
           L+    ++      +K +   Q+
Sbjct: 538 LERKKRIDEIMKRTRKSDVPPQV 560


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,121,806
Number of Sequences: 37866
Number of extensions: 1385957
Number of successful extensions: 11884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 267
Number of HSP's successfully gapped in prelim test: 775
Number of HSP's that attempted gapping in prelim test: 7482
Number of HSP's gapped (non-prelim): 3621
length of query: 685
length of database: 18,247,518
effective HSP length: 109
effective length of query: 576
effective length of database: 14,120,124
effective search space: 8133191424
effective search space used: 8133191424
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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