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Search of human proteins with 209571519
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo
sapiens]
(1503 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 3419 0.0
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 1585 0.0
gi|37693519 BMP-binding endothelial regulator precursor protein ... 394 e-109
gi|134031945 SCO-spondin [Homo sapiens] 255 3e-67
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 254 6e-67
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 231 4e-60
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 231 4e-60
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 226 2e-58
gi|108773804 Fraser syndrome 1 [Homo sapiens] 217 6e-56
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 211 3e-54
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 208 4e-53
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 208 4e-53
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 199 1e-50
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 199 2e-50
gi|134268640 tectorin alpha precursor [Homo sapiens] 198 3e-50
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 189 2e-47
gi|116284392 mucin 2 precursor [Homo sapiens] 189 2e-47
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 189 2e-47
gi|161019170 mucin 5AC [Homo sapiens] 176 2e-43
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 176 2e-43
gi|151301154 mucin 6, gastric [Homo sapiens] 164 5e-40
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 160 7e-39
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 160 7e-39
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 160 7e-39
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 160 9e-39
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 160 9e-39
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 160 9e-39
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 150 9e-36
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 150 9e-36
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 144 5e-34
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 3419 bits (8864), Expect = 0.0
Identities = 1503/1503 (100%), Positives = 1503/1503 (100%)
Query: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL
Sbjct: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
Query: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ 120
GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ
Sbjct: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ 120
Query: 121 DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLE 180
DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLE
Sbjct: 121 DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLE 180
Query: 181 SCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARP 240
SCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARP
Sbjct: 181 SCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARP 240
Query: 241 LPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIP 300
LPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIP
Sbjct: 241 LPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIP 300
Query: 301 GQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGR 360
GQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGR
Sbjct: 301 GQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGR 360
Query: 361 QLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 420
QLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP
Sbjct: 361 QLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 420
Query: 421 SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPR 480
SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPR
Sbjct: 421 SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPR 480
Query: 481 CPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCS 540
CPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCS
Sbjct: 481 CPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCS 540
Query: 541 GCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA 600
GCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA
Sbjct: 541 GCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA 600
Query: 601 PAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCD 660
PAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCD
Sbjct: 601 PAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCD 660
Query: 661 GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCE 720
GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCE
Sbjct: 661 GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCE 720
Query: 721 YLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRY 780
YLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRY
Sbjct: 721 YLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRY 780
Query: 781 HGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQ 840
HGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQ
Sbjct: 781 HGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQ 840
Query: 841 GREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHG 900
GREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHG
Sbjct: 841 GREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHG 900
Query: 901 EEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRK 960
EEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRK
Sbjct: 901 EEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRK 960
Query: 961 YEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCA 1020
YEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCA
Sbjct: 961 YEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCA 1020
Query: 1021 EALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCR 1080
EALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCR
Sbjct: 1021 EALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCR 1080
Query: 1081 APTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCC 1140
APTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCC
Sbjct: 1081 APTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCC 1140
Query: 1141 PRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVA 1200
PRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVA
Sbjct: 1141 PRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVA 1200
Query: 1201 WTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW 1260
WTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW
Sbjct: 1201 WTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW 1260
Query: 1261 DGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPG 1320
DGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPG
Sbjct: 1261 DGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPG 1320
Query: 1321 RPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGP 1380
RPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGP
Sbjct: 1321 RPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGP 1380
Query: 1381 GSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQ 1440
GSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQ
Sbjct: 1381 GSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQ 1440
Query: 1441 HIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQVLLTGDQPLGARPSPSREPQ 1500
HIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQVLLTGDQPLGARPSPSREPQ
Sbjct: 1441 HIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQVLLTGDQPLGARPSPSREPQ 1500
Query: 1501 ETP 1503
ETP
Sbjct: 1501 ETP 1503
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 1585 bits (4104), Expect = 0.0
Identities = 704/779 (90%), Positives = 707/779 (90%), Gaps = 61/779 (7%)
Query: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL
Sbjct: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
Query: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ 120
GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ
Sbjct: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ 120
Query: 121 DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQC------QGP--- 171
DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCL G + C +GP
Sbjct: 121 DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE 180
Query: 172 ------------------------------SCSELNCLES--------CTP--------- 184
C + CL S C P
Sbjct: 181 PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLR 240
Query: 185 PGECCPIC--CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP 242
PG CCP C CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP
Sbjct: 241 PGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP 300
Query: 243 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 302
GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ
Sbjct: 301 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 360
Query: 303 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 362
CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL
Sbjct: 361 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 420
Query: 363 CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 422
CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC
Sbjct: 421 CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 480
Query: 423 DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP 482
DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP
Sbjct: 481 DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP 540
Query: 483 DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC 542
DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC
Sbjct: 541 DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC 600
Query: 543 AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQC---P 599
AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQC P
Sbjct: 601 AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP 660
Query: 600 APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC 659
APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC
Sbjct: 661 APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC 720
Query: 660 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG
Sbjct: 721 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 779
Score = 524 bits (1349), Expect = e-148
Identities = 276/748 (36%), Positives = 347/748 (46%), Gaps = 63/748 (8%)
Query: 302 QCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
+C P C G + + E C C CQ G C Q LP
Sbjct: 88 ECHPASPQCWGLGRAWPEGARW---EPDACTACVCQDGAAHCGPQ------AHLPH---- 134
Query: 362 LCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPS 421
C C +G+ + G + PD CT C C +G C CP PC P GACCP
Sbjct: 135 -CRGCSQNGQTYGNGETFSPDA--CTTCRCLEGTITCNQKPCPRGPCPEP----GACCPH 187
Query: 422 CD-SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPR 480
C C Y Q+Y G F + +PC C C V C + CPP+ C P PG CCP
Sbjct: 188 CKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPT 247
Query: 481 CPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC---AHPLPGTCCPN 537
C C + G+ ++ P DPC+ CRC EGH C+ R C C A PLPGTCCP
Sbjct: 248 CQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASL-CPYPARPLPGTCCPV 306
Query: 538 DCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQ 597
C GC G+E+ SG DPC CRC +G+VQC C P+PC P +PG+CCP
Sbjct: 307 -CDGCFLNGREHRSGEPVGS-GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPV 364
Query: 598 CPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQG-PCC 656
C GC G + + + C RC C G VSC+ CP PCA P G C
Sbjct: 365 CD---GCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLC 421
Query: 657 PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR--GDCCP 714
P+C+ G+EFA G ++ C C+C +G C C PA C P + G CCP
Sbjct: 422 PACE---LDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 478
Query: 715 DCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPT 774
CD C Y + Y + Q F D PC+ C C G VTC C P C+ P G CCP
Sbjct: 479 SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPR 538
Query: 775 CQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVC 834
C C GE+ P DP C C CQEG CQ +PCP A C HP PG C C
Sbjct: 539 CPDCILEEEVFVDGESFSHPRDP-CQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDC 597
Query: 835 HSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRC- 893
C G+E+ G +F P+ C CRC +G V C+ +C PLPC V G CCP+C
Sbjct: 598 SGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCP 657
Query: 894 -----RGCLAHGEEHPEGSRWV-PPDSACSSCVCHEGVVTCARIQC-ISSCAQPRQGPHD 946
GC G H + PP C C+C +G V+C R+ C + CA PRQGP
Sbjct: 658 AAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGP-- 715
Query: 947 CCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQC-PSLVGCPPS 1005
CCP C C ++G+++ GE F C +C+C EG S+ C + C P+L CP
Sbjct: 716 CCPSCDGCLYQGKEFASGERFPSPTAACHLCLCW---EG--SVSCEPKACAPAL--CP-- 766
Query: 1006 QLLPPGPQHCCPTC---AEALSNCSEGL 1030
P CCP C + +C G+
Sbjct: 767 ---FPARGDCCPDCDGEGHGIGSCRGGM 791
Score = 445 bits (1145), Expect = e-124
Identities = 253/737 (34%), Positives = 323/737 (43%), Gaps = 116/737 (15%)
Query: 476 QCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCC 535
+C P P C + +G + D C C CQ+G AHC P+ AH LP
Sbjct: 88 ECHPASPQCWGLGRAWPEGARWEP--DACTACVCQDGAAHCGPQ-------AH-LP---- 133
Query: 536 PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
C GC+ G+ Y +G F D C CRCL G + C + C PCPEP G CC
Sbjct: 134 --HCRGCSQNGQTYGNGETFS--PDACTTCRCLEGTITCNQKPCPRGPCPEP----GACC 185
Query: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP--RQG 653
P C GC G + + S +PC +C CL V C L CPP+PC P R G
Sbjct: 186 PHCKP--GCDYEGQLYEEGVTFLSS-SNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPG 242
Query: 654 PCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR---G 710
CCP+C GC G + G+ + +P C +C C EG + C + CA +LCP+PAR G
Sbjct: 243 HCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECA-SLCPYPARPLPG 301
Query: 711 DCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGH 770
CCP CDGC G + S + +PC+ C C G V C PC P C HP G
Sbjct: 302 TCCPVCDGCFLNGREHRSGEPVGSG-DPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 360
Query: 771 CCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCF 830
CCP C GC Y G S ET C C+CQ G + C+++ CP C P+ G
Sbjct: 361 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 420
Query: 831 CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCC 890
CP C G E +G ++E C C CQ G C + CPP PC+ G+CC
Sbjct: 421 CPACEL---DGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACC 477
Query: 891 PRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCI-SSCAQPRQGPHDCCP 949
P C C H + + G + DS C +C C +G VTC+ + C ++CA+P+ GP CCP
Sbjct: 478 PSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP 537
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICE----------------------------- 980
+C DC E + GESF DPC+ C C+
Sbjct: 538 RCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDC 597
Query: 981 ----------------PQPEGPPSL--------RCHRRQCPSLVGCPPSQLLPPGPQHCC 1016
P P P L +C R+C L CP LLP CC
Sbjct: 598 SGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLP-CPEPVLLPG---ECC 653
Query: 1017 PTCAEALSNCSEGLLGSELA--------PPDPCYTCQCQDLTWLCIHQACPELSCPLSER 1068
P C A + G+ A P DPC C C D + C CP C
Sbjct: 654 PQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCA---- 709
Query: 1069 HTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDT--CTSCSCMAGTVRCQSQRCSPLSC 1126
H G CCP C C++QG+E ASGER+ T C C C G+V C+ P +C
Sbjct: 710 HPRQGPCCPSC----DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCE-----PKAC 760
Query: 1127 GPDKAPALSPGSCCPRC 1143
P P + G CCP C
Sbjct: 761 APALCPFPARGDCCPDC 777
Score = 409 bits (1051), Expect = e-113
Identities = 232/629 (36%), Positives = 295/629 (46%), Gaps = 69/629 (10%)
Query: 546 GKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCP 605
G+ +P GA + D C C C G C P P C GC
Sbjct: 100 GRAWPEGARWE--PDACTACVCQDGAAHCG---------------PQAHLPHC---RGCS 139
Query: 606 RPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCD-GCLY 664
+ G + + E FSP D C C CL+G+++C + PCP PC P G CCP C GC Y
Sbjct: 140 QNGQTYG-NGETFSP--DACTTCRCLEGTITCNQKPCPRGPCPEP--GACCPHCKPGCDY 194
Query: 665 QGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR--GDCCPDCDGCEYL 722
+G+ + G F S + C C C V C C P+ CP P G CCP C GC
Sbjct: 195 EGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEG 254
Query: 723 GESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIP-SGHCCPTCQGCRYH 781
G + QE+ P +PC +C CL G + C +R C C +P P G CCP C GC +
Sbjct: 255 GSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASL-CPYPARPLPGTCCPVCDGCFLN 313
Query: 782 GVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPS--PGPCFCPVCHSCLS 839
G SGE + DP CS C C GS++C+ PCPP C HP PG C CPVC C
Sbjct: 314 GREHRSGEPVGSG-DP-CSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQC-CPVCDGCEY 370
Query: 840 QGREHQDGEEFE-GPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLA 898
QG ++Q E F G C C CQAG+VSC +CP PC L + R CP C
Sbjct: 371 QGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGR-QLCPACE---L 426
Query: 899 HGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISS-CAQPRQGPHDCCPQCSDCEHE 957
GEE EG +W P C++CVC +GV C + C + C P Q P CCP C C +
Sbjct: 427 DGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYH 486
Query: 958 GRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPP--GPQHC 1015
+ Y G++F PC C C+ ++ C SLV CPP+ P GP C
Sbjct: 487 SQVYANGQNFTDADSPCHACHCQDG-----TVTC------SLVDCPPTTCARPQSGPGQC 535
Query: 1016 CPTCAEALSNCSEGLLGSELAPP-DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGS 1074
CP C + + + G + P DPC C+CQ+ C + CP C H PG+
Sbjct: 536 CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA----HPLPGT 591
Query: 1075 CCPVCRAPTQSCVHQGREVASGERWT--VDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAP 1132
CCP C G+E SG + D C C C++G V+C ++RC PL C P
Sbjct: 592 CCP---NDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPC---PEP 645
Query: 1133 ALSPGSCCPRC--LPRPASCMAFGDPHYR 1159
L PG CCP+C P PA C G H R
Sbjct: 646 VLLPGECCPQCPAAPAPAGCPRPGAAHAR 674
Score = 150 bits (380), Expect = 7e-36
Identities = 107/330 (32%), Positives = 136/330 (41%), Gaps = 66/330 (20%)
Query: 858 EWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACS 917
EW V +R Q L +++ E C P C G PEG+RW P AC+
Sbjct: 58 EWLGRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEP--DACT 115
Query: 918 SCVCHEGVVTC---ARIQCISSCAQ----------------------------------- 939
+CVC +G C A + C+Q
Sbjct: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPR 175
Query: 940 -PRQGPHDCCPQCS-DCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCP 997
P P CCP C C++EG+ YE G +F ++PC C C LR R +C
Sbjct: 176 GPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTC---------LR-SRVRCM 225
Query: 998 SLVGCPPSQLLPP--GPQHCCPTCAEALSNCSEGLLGSE-LAPPDPCYTCQCQDLTWLCI 1054
+L CPPS P P HCCPTC S G E P DPC C+C + C
Sbjct: 226 AL-KCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 284
Query: 1055 HQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER-WTVDTCTSCSCMAGT 1113
+ C L CP R PG+CCPVC C GRE SGE + D C+ C C G+
Sbjct: 285 QRECASL-CPYPARPL-PGTCCPVC----DGCFLNGREHRSGEPVGSGDPCSHCRCANGS 338
Query: 1114 VRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143
V+C+ C P+ C + P PG CCP C
Sbjct: 339 VQCEPLPCPPVPC---RHPGKIPGQCCPVC 365
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/102 (26%), Positives = 31/102 (30%), Gaps = 35/102 (34%)
Query: 1079 CRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCG----------- 1127
C + C GR G RW D CT+C C G C Q P G
Sbjct: 89 CHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG 148
Query: 1128 ----PD--------------------KAPALSPGSCCPRCLP 1145
PD + P PG+CCP C P
Sbjct: 149 ETFSPDACTTCRCLEGTITCNQKPCPRGPCPEPGACCPHCKP 190
>gi|37693519 BMP-binding endothelial regulator precursor protein [Homo
sapiens]
Length = 685
Score = 394 bits (1013), Expect = e-109
Identities = 223/651 (34%), Positives = 310/651 (47%), Gaps = 60/651 (9%)
Query: 857 CEWCRCQAGQVSCVRLQCPPLP--CKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDS 914
C C C +V+C R +CP L C L + +RG+CC +C+GC G + +W P
Sbjct: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAE 126
Query: 915 ACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPC 974
C C EGVVT + ++C+ C P + CCP C C EG +Y+ GE FQP C
Sbjct: 127 PCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC 186
Query: 975 EVCICEPQPEGPPSLRCHRRQCPSLVGCPPS-QLLPPGPQHCCPTC-------------- 1019
C C +C R CP ++ CP +PPG CCP C
Sbjct: 187 TKCSCT-----GGRTQCVREVCP-ILSCPQHLSHIPPG--QCCPKCLGQRKVFDLPFGSC 238
Query: 1020 ---AEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
++ N S L D C C C+D T +C + C + CC
Sbjct: 239 LFRSDVYDNGSSFLY-------DNCTACTCRDSTVVCKRKCSHPGGCDQGQE-----GCC 286
Query: 1077 PVC--RAPTQS---CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKA 1131
C R P + C + GE W+ CT C+C+ G C++++C P+S P +
Sbjct: 287 EECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCP-QG 345
Query: 1132 PALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHS--GDFSVHV 1189
L+ CCP C +P C FGDPHY TFDGR +FQG+C YVL KDC S F V V
Sbjct: 346 KILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLV 405
Query: 1190 TNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVI 1249
ND R +WT+ V ++LG+ V L Q V +G +ALP + P +++L G+ +
Sbjct: 406 KNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALP-CRAPHFHIDLDGYLLK 464
Query: 1250 LHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGN 1309
+ + GL++ WDG S VEV +G+ CGLCGN+NG +DDL G +G F
Sbjct: 465 VTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAE 524
Query: 1310 SWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFA 1369
SW+V + RP + V + + A+ C LKS F CH+ V F+
Sbjct: 525 SWRVESNEFCNRP--QRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYR 582
Query: 1370 ACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDEC 1429
+CV D+C C + C C++ AY C++ G+ W C + G V+D C
Sbjct: 583 SCVTDMCECPVHKN---CYCESFLAYTRACQREGIKVHWEPQQNC-AATQCKHGAVYDTC 638
Query: 1430 GPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
GP C +TC N + +G C +PCV GC CPA LV H+ CI P CPQ
Sbjct: 639 GPGCIKTCDNWN-EIGP----CNKPCVAGCHCPANLVLHKGRCIKPVLCPQ 684
Score = 153 bits (387), Expect = 1e-36
Identities = 96/319 (30%), Positives = 136/319 (42%), Gaps = 48/319 (15%)
Query: 738 PCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPL 795
PC +C CL VTC R C C+ + G CC C+GC Y G T S P
Sbjct: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
Query: 796 DPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--GPCFCPVCHSCLSQGREHQDGEEFEGP 853
+P C L CQEG + C C +P G C CP C C+ +G ++Q+GEEF+
Sbjct: 126 EP-CVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMC-CPTCPGCVFEGVQYQEGEEFQPE 182
Query: 854 AGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTE--RGSCCPRCRG-----------CLAHG 900
C C C G+ CVR CP L C ++ G CCP+C G CL
Sbjct: 183 GSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRS 242
Query: 901 EEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQP---RQGPHDCCPQC------ 951
+ + GS ++ + C++C C + V C R C+ P QG CC +C
Sbjct: 243 DVYDNGSSFLYDN--CTACTCRDSTVVCKR-----KCSHPGGCDQGQEGCCEECLLRVPP 295
Query: 952 ---SDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLL 1008
C+ + ++ GE + + C +C C C +QC + CP ++L
Sbjct: 296 EDIKVCKFGNKIFQDGEMW--SSINCTICACV-----KGRTECRNKQCIPISSCPQGKIL 348
Query: 1009 PPGPQHCCPTCAEALSNCS 1027
+ CCP C E C+
Sbjct: 349 --NRKGCCPICTEKPGVCT 365
Score = 150 bits (380), Expect = 7e-36
Identities = 112/346 (32%), Positives = 148/346 (42%), Gaps = 66/346 (19%)
Query: 239 RPLPG-TCCPV----CDGC-------FLNG---REHRSGE----PVGSGDPCSHCRCANG 279
R PG TCC + C G FL G + GE P + +PC C C N
Sbjct: 16 RRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNK 75
Query: 280 SVQCEPLPCPPVP--CRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL-CVRCSC 336
V C+ CP + C K G CC C GC Y+G+ Y S +F+ Q CV C
Sbjct: 76 EVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNS--SFKWQSPAEPCVLRQC 133
Query: 337 QAGEVSCEEQECPVTPCALPASGRQLC----PACELDGEEFAEGVQWEPDGRPCTACVCQ 392
Q G V+ C V C P +C P C +G ++ EG +++P+G CT C C
Sbjct: 134 QEGVVTESGVRC-VVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCT 192
Query: 393 DGVPKCGAVLCPPAPC-QHPTQ-PPGACCPSC-----------DSCTYHSQVYANGQNFT 439
G +C +CP C QH + PPG CCP C SC + S VY NG +F
Sbjct: 193 GGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFL 252
Query: 440 DADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRC-----PD----CILEEEV 490
+ C AC C+D TV C P C + Q G CC C P+ C ++
Sbjct: 253 YDN--CTACTCRDSTVVCKRKCSHPGGCDQGQEG---CCEECLLRVPPEDIKVCKFGNKI 307
Query: 491 FVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
F DGE +S C C C +G C+ + C +P + CP
Sbjct: 308 FQDGEMWSSIN--CTICACVKGRTECRNKQC--------IPISSCP 343
Score = 135 bits (341), Expect = 2e-31
Identities = 94/320 (29%), Positives = 121/320 (37%), Gaps = 38/320 (11%)
Query: 366 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCP--PAPCQHPTQPPGACCPSCD 423
CE +GE + + D PC CVC + C CP C + GACC C
Sbjct: 50 CENEGEVLQ--IPFITDN-PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK 106
Query: 424 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPD 483
CTY Y + + PC CQ+G VT S V C C P G CCP CP
Sbjct: 107 GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPG 165
Query: 484 CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC----AHPLPGTCCPNDC 539
C+ E + +GE F C +C C G C CP C +H PG CCP C
Sbjct: 166 CVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK-C 224
Query: 540 SG-----------CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 588
G C F Y +G+ F + D C C C V C + P C +
Sbjct: 225 LGQRKVFDLPFGSCLFRSDVYDNGSSFLY--DNCTACTCRDSTVVCKRKCSHPGGCDQG- 281
Query: 589 LLPGECCPQC-----PAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC- 642
CC +C P + G + E +S C C C+ G C+ C
Sbjct: 282 --QEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCI 337
Query: 643 PPAPCAHPR---QGPCCPSC 659
P + C + + CCP C
Sbjct: 338 PISSCPQGKILNRKGCCPIC 357
Score = 128 bits (322), Expect = 4e-29
Identities = 87/298 (29%), Positives = 117/298 (39%), Gaps = 38/298 (12%)
Query: 156 CTTCRCLTGAVQCQGPSCSELN--CLESCTPPGECCPIC--CTEGGSHWEHGQEWTTPGD 211
C C CL V C+ C L+ C + G CC C CT G+ + +W +P +
Sbjct: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAE 126
Query: 212 PCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDP 270
PC + +C EG + C C P L G CCP C GC G +++ GE G
Sbjct: 127 PCVLRQCQEGVVTESGVRCVVHCKNPLEHL-GMCCPTCPGCVFEGVQYQEGEEFQPEGSK 185
Query: 271 CSHCRCANGSVQCEPLPCPPVPC-RHPGKI-PGQCCPVCDG-----------CEYQGHQY 317
C+ C C G QC CP + C +H I PGQCCP C G C ++ Y
Sbjct: 186 CTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVY 245
Query: 318 QSQETFRLQERGLCVRCSCQAGEVSCEE-----------QECPVTPCALPASGRQLCPAC 366
+ +F C C+C+ V C+ QE C L + C
Sbjct: 246 DNGSSFLYDN---CTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDI-KVC 301
Query: 367 ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC-PPAPC-QHPTQPPGACCPSC 422
+ + F +G W CT C C G +C C P + C Q CCP C
Sbjct: 302 KFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
Score = 127 bits (320), Expect = 6e-29
Identities = 85/305 (27%), Positives = 122/305 (40%), Gaps = 42/305 (13%)
Query: 211 DPCRICRCLEGHIQCRQRECASLCPYPARPLP--GTCCPVCDGCFLNGREHRSGEPVGS- 267
+PC +C CL + C++ +C L A + G CC C GC G + S S
Sbjct: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSP 124
Query: 268 GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQE 327
+PC +C G V + C V C++P + G CCP C GC ++G QYQ E F+ E
Sbjct: 125 AEPCVLRQCQEGVVTESGVRC-VVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQ-PE 182
Query: 328 RGLCVRCSCQAGEVSCEEQECPVTPCALPAS---GRQLCP--------------ACELDG 370
C +CSC G C + CP+ C S Q CP +C
Sbjct: 183 GSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRS 242
Query: 371 EEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC-------- 422
+ + G + D CTAC C+D C P C Q CC C
Sbjct: 243 DVYDNGSSFLYDN--CTACTCRDSTVVCKRKCSHPGGCD---QGQEGCCEECLLRVPPED 297
Query: 423 -DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQS---GPGQCC 478
C + ++++ +G+ ++ + C C C G C C P + PQ CC
Sbjct: 298 IKVCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPISSC-PQGKILNRKGCC 354
Query: 479 PRCPD 483
P C +
Sbjct: 355 PICTE 359
Score = 126 bits (316), Expect = 2e-28
Identities = 94/339 (27%), Positives = 134/339 (39%), Gaps = 54/339 (15%)
Query: 560 DPCRLCRCLSGNVQCLARRCVPLP--CPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEY 617
+PC +C CL+ V C +C L C + G CC QC GC G + ++
Sbjct: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK---GCTYEGNTYNSSFKW 121
Query: 618 FSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ--GPCCPSCDGCLYQGKEFASGERF 675
SP +PC C +G V+ + C C +P + G CCP+C GC+++G ++ GE F
Sbjct: 122 QSP-AEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEF 179
Query: 676 PSPTAACHLCLCWEGSVSCEPKACAPALCP----FPARGDCCPDCDG-----------CE 720
+ C C C G C + C CP G CCP C G C
Sbjct: 180 QPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCL 239
Query: 721 YLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTC----- 775
+ + Y + F + C CTC V C R+ P GC CC C
Sbjct: 240 FRSDVYDNGSSF--LYDNCTACTCRDSTVVCKRKCSHPGGCDQ---GQEGCCEECLLRVP 294
Query: 776 ----QGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPC-PPALCPHP---SPG 827
+ C++ GE C++C C +G C+ K C P + CP +
Sbjct: 295 PEDIKVCKFGNKIFQDGEMWS---SINCTICACVKGRTECRNKQCIPISSCPQGKILNRK 351
Query: 828 PCFCPVCHS----CLSQGREHQ---DGEEFEGPAGSCEW 859
C CP+C C G H DG F G+C++
Sbjct: 352 GC-CPICTEKPGVCTVFGDPHYNTFDGRTFNF-QGTCQY 388
Score = 121 bits (303), Expect = 6e-27
Identities = 92/328 (28%), Positives = 126/328 (38%), Gaps = 46/328 (14%)
Query: 788 GETLPDPL--DPTCSLCTCQEGSMRCQKKPCP----PALCPHPSPGPCFCPVCHSCLSQG 841
GE L P D C +C C + C+++ CP G C C C C +G
Sbjct: 54 GEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGAC-CEQCKGCTYEG 112
Query: 842 REHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGE 901
+ +++ PA C +CQ G V+ ++C + CK + G CCP C GC+ G
Sbjct: 113 NTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRC-VVHCKNPLEHLGMCCPTCPGCVFEGV 171
Query: 902 EHPEGSRWVPPDSACSSCVCHEGVVTCARIQC-ISSCAQ--PRQGPHDCCPQC------- 951
++ EG + P S C+ C C G C R C I SC Q P CCP+C
Sbjct: 172 QYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVF 231
Query: 952 ----SDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQL 1007
C Y+ G SF D C C C ++ C +R+C GC
Sbjct: 232 DLPFGSCLFRSDVYDNGSSFL--YDNCTACTCRDS-----TVVC-KRKCSHPGGC----- 278
Query: 1008 LPPGPQHCCPTC-----AEALSNCSEG---LLGSELAPPDPCYTCQCQDLTWLCIHQAC- 1058
G + CC C E + C G E+ C C C C ++ C
Sbjct: 279 -DQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCI 337
Query: 1059 PELSCPLSERHTPPGSCCPVCRAPTQSC 1086
P SCP + G CCP+C C
Sbjct: 338 PISSCPQGKILNRKG-CCPICTEKPGVC 364
Score = 96.7 bits (239), Expect = 2e-19
Identities = 78/285 (27%), Positives = 109/285 (38%), Gaps = 50/285 (17%)
Query: 114 CTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDA--CTTCRCLTGAVQCQGP 171
C + Q GA C Q C+GC+ G TY + + A C +C G V G
Sbjct: 91 CALAIKQRGA--CCEQ-----CKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGV 143
Query: 172 SCSELNCLESCTPPGECCPIC--CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
C ++C G CCP C C G ++ G+E+ G C C C G QC +
Sbjct: 144 RC-VVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
Query: 230 CASL-CPYPARPL-PGTCCPVCDG-----------CFLNGREHRSGEPVGSGDPCSHCRC 276
C L CP + PG CCP C G C + +G D C+ C C
Sbjct: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSF-LYDNCTACTC 261
Query: 277 ANGSVQCEPLPCPPVPCRHPGKI-PGQ--CCPVC---------DGCEYQGHQYQSQETFR 324
+ +V C+ C HPG GQ CC C C++ +Q E +
Sbjct: 262 RDSTVVCKR------KCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWS 315
Query: 325 LQERGLCVRCSCQAGEVSCEEQEC-PVTPC--ALPASGRQLCPAC 366
C C+C G C ++C P++ C + + CP C
Sbjct: 316 SIN---CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
Score = 80.5 bits (197), Expect = 1e-14
Identities = 62/242 (25%), Positives = 90/242 (37%), Gaps = 54/242 (22%)
Query: 58 EWLGRLEAAVMELREQNKDLQTRVRQLESCE--------CHPASPQCWGLGRAWPEGARW 109
+W E V+ ++ ++ VR + C+ C P P C G + EG +
Sbjct: 120 KWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEF 179
Query: 110 EPDA--CTACVCQDGAAHCGPQA--------HLPH---------CRG-----------CS 139
+P+ CT C C G C + HL H C G C
Sbjct: 180 QPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCL 239
Query: 140 QNGQTYGNGETFSPDACTTCRCLTGAVQCQ-------GPSCSELNCLESC---TPPGECC 189
Y NG +F D CT C C V C+ G + C E C PP +
Sbjct: 240 FRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDI- 298
Query: 190 PICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQREC--ASLCPYPARPLPGTCCP 247
C G ++ G+ W++ C IC C++G +CR ++C S CP CCP
Sbjct: 299 -KVCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCP 355
Query: 248 VC 249
+C
Sbjct: 356 IC 357
Score = 54.3 bits (129), Expect = 9e-07
Identities = 48/200 (24%), Positives = 68/200 (34%), Gaps = 60/200 (30%)
Query: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCR----------------AP 1082
+PC C C + C + CP LS + G+CC C+ +P
Sbjct: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSP 124
Query: 1083 TQSCV----HQGREVASGERWTV-------------DTC--------------------- 1104
+ CV +G SG R V TC
Sbjct: 125 AEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGS 184
Query: 1105 --TSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCL-PRPASCMAFGDPHYRT- 1160
T CSC G +C + C LSC P + PG CCP+CL R + FG +R+
Sbjct: 185 KCTKCSCTGGRTQCVREVCPILSC-PQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSD 243
Query: 1161 -FDGRLLHFQGSCSYVLAKD 1179
+D +C+ +D
Sbjct: 244 VYDNGSSFLYDNCTACTCRD 263
Score = 50.4 bits (119), Expect = 1e-05
Identities = 35/124 (28%), Positives = 50/124 (40%), Gaps = 35/124 (28%)
Query: 103 WPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQ------------------T 144
+ G+ + D CTAC C+D C + H GC Q +
Sbjct: 245 YDNGSSFLYDNCTACTCRDSTVVC--KRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK 302
Query: 145 YGN-----GETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGE------CCPICC 193
+GN GE +S CT C C+ G +C+ C ++ SC P G+ CCPIC
Sbjct: 303 FGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPIS---SC-PQGKILNRKGCCPICT 358
Query: 194 TEGG 197
+ G
Sbjct: 359 EKPG 362
Score = 31.2 bits (69), Expect = 7.9
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 1086 CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSP-GSCCPRC 1143
C ++G EV T + C C C+ V C+ ++C LS D A A+ G+CC +C
Sbjct: 50 CENEG-EVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLS--RDCALAIKQRGACCEQC 105
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 255 bits (651), Expect = 3e-67
Identities = 206/666 (30%), Positives = 270/666 (40%), Gaps = 118/666 (17%)
Query: 816 CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCP 875
C A+C C CPV + R Q+G S W Q C + CP
Sbjct: 783 CLAAVCGCDPGSDCLCPVLSAYAR--RCAQEG-------ASPPW----RNQTLCP-VMCP 828
Query: 876 PLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCIS 935
E C P C E+ E S + C C G++ QC+
Sbjct: 829 G------GQEYRECAPACGQHCGKPEDCGELG------SCVAGCNCPLGLLWDPEGQCV- 875
Query: 936 SCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQ 995
P CP C+ R+Y PG + C CIC+ + C R
Sbjct: 876 --------PPSLCP----CQLGARRYAPGSATMK---ECNRCICQERG----LWNCTARH 916
Query: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
CPS CP + PG C TC +N S D C
Sbjct: 917 CPSQAFCPRELVYAPGA--CLLTCDSPSANHS-----CPAGSTDGC-------------- 955
Query: 1056 QACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVR 1115
CP + L ER PP C C H G+ D C C C
Sbjct: 956 -VCPPGTVLLDERCVPPDLC---------PCRHSGQWYLPNATIQED-CNVCVCRGRQWH 1004
Query: 1116 CQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYV 1175
C QR R C A G PHY TFDG + G+C Y+
Sbjct: 1005 CTGQR-------------------------RSGRCQASGAPHYVTFDGLAFTYPGACEYL 1039
Query: 1176 LAKDCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQ 1235
L ++ SG F+V N G SG+ T+ +AV L V +L+ AVTV+G V P +
Sbjct: 1040 LVREA-SGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVY 1098
Query: 1236 E-PLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQ 1294
P L + G ++L GL +LWDG ++V V + ++GR GLCG+F+G A +DL+
Sbjct: 1099 TGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLR 1158
Query: 1295 GPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSP 1354
+G+L P+ +SW++S L P G PC +RA A ARCG L
Sbjct: 1159 SRQGVLEPTAELAAHSWRLSP-LCP----EPGDLPHPCTMNTHRA-GWARARCGALLQPL 1212
Query: 1355 FSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLC 1414
F+ CHA VPP+ + C+YD C C G + CLC A+ YA C + G WR LC
Sbjct: 1213 FTLCHAEVPPQQHYEWCLYDACGCDSGGDCE-CLCSAIATYADECARHGHHVRWRSQELC 1271
Query: 1415 VVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC-VRPCVPGCQCPAGLVEHEAHCI 1473
+ C E G V++ CGP CP TC QH E HC V CV GC CP G + H C+
Sbjct: 1272 SLQC--EGGQVYEACGPTCPPTCHEQH---PEPGWHCQVVACVEGCFCPEGTLLHGGACL 1326
Query: 1474 PPEACP 1479
P +CP
Sbjct: 1327 EPASCP 1332
Score = 203 bits (516), Expect = 1e-51
Identities = 148/443 (33%), Positives = 195/443 (44%), Gaps = 50/443 (11%)
Query: 1060 ELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAG-----TV 1114
E CP + ++ S CP P+ V QG E + E + + C C G T+
Sbjct: 466 ERLCPGGQLYSDCVSLCP----PSCEAVGQGEEESCRE----ECVSGCECPRGLFWNGTL 517
Query: 1115 RCQSQRCSPLSCGPDKAPALSPGSCCPRCLPR-----------PASCMAFGDPHYRTFDG 1163
+ C C P + C C+ R PA C GD HY TFDG
Sbjct: 518 CVPAAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDG 577
Query: 1164 RLLHFQGS--CSYVLAKDCHSGDFSVHVTND--DRGRSGVAWTQEVAVLLGDMAVRLLQD 1219
R F G C Y L +D G + + + D G + ++V L D ++L
Sbjct: 578 RSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAG----SCLHAISVSLEDTHIQLRDS 633
Query: 1220 GAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVE-VSVPGSYQGRT 1278
GAV V+G V LP++ L V +L PG QVLW V +++ + +
Sbjct: 634 GAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQV 693
Query: 1279 CGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR-PCSAGREVDPCRAAGY 1337
GLCG F QDD P G + S AAF + +QV+ GR P + PC
Sbjct: 694 QGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---KGRCPSEDSALLSPCTTHSQ 750
Query: 1338 RARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYAS 1397
R A A C +L SS F CH +V EPF+ C+ +C C PGS CLC L AYA
Sbjct: 751 R-HAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSD---CLCPVLSAYAR 806
Query: 1398 HCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP 1457
C Q G +P WR TLC V CP G + EC P C + C + GEL + CV
Sbjct: 807 RCAQEGASPPWRNQTLCPVMCP--GGQEYRECAPACGQHC-GKPEDCGELGS-----CVA 858
Query: 1458 GCQCPAGLV-EHEAHCIPPEACP 1479
GC CP GL+ + E C+PP CP
Sbjct: 859 GCNCPLGLLWDPEGQCVPPSLCP 881
Score = 156 bits (394), Expect = 2e-37
Identities = 142/485 (29%), Positives = 203/485 (41%), Gaps = 73/485 (15%)
Query: 1015 CCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGS 1074
CCP A +C+E L ++ +P C+ W C QA + GS
Sbjct: 94 CCPGWGGA--HCTEAL--AKASPEGHCFAM------WQCQLQA--------GSANASAGS 135
Query: 1075 CCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPAL 1134
C P G+ W + +C R S R P G +PAL
Sbjct: 136 LEECCARPW------------GQSWWDGSSQAC-------RSCSSRHLP---GSASSPAL 173
Query: 1135 ------SPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH 1188
+ G + A+C ++ HYRTFDGR HF G C+Y+LA S ++VH
Sbjct: 174 LQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVH 232
Query: 1189 VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY---VELRG 1245
+T DR + V +G V L+Q G V+V G V P Q LL+ ++ G
Sbjct: 233 LTPGDRCPQPGHCQR---VTMGPEEV-LIQAGNVSVKGQLV--PEGQSWLLHGLSLQWLG 286
Query: 1246 HTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEA 1305
++L G+ V D + +SV G+T GLCG +NG+ +DD P G L A
Sbjct: 287 DWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAA 346
Query: 1306 AFGNSWQVS-------EGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRC 1358
FGNSW++ + + + C +D G+ R EA C L PF +C
Sbjct: 347 TFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGH-LRAEAQDVCHQLLEGPFGQC 405
Query: 1359 HAVVPPEPFFAACVYDLCA---CGPGSSA-DACLCDALEAYASHCRQAGVTPTWRGPTLC 1414
HA V P + AC++ CA G G +C +Y C + + WR P C
Sbjct: 406 HAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFC 465
Query: 1415 VVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIP 1474
CP G ++ +C CP +C + + GE C CV GC+CP GL + C+P
Sbjct: 466 ERLCP--GGQLYSDCVSLCPPSC--EAVGQGE-EESCREECVSGCECPRGLFWNGTLCVP 520
Query: 1475 PEACP 1479
CP
Sbjct: 521 AAHCP 525
Score = 151 bits (381), Expect = 5e-36
Identities = 416/1761 (23%), Positives = 529/1761 (30%), Gaps = 510/1761 (28%)
Query: 79 TRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACV--CQDGAAHCGPQAHLP--- 133
T +E E P P C P D CV CQ G +C P L
Sbjct: 3309 TNCTAIEGAEYSPCGPPC-------PRSC----DDLVHCVWRCQPGC-YCPPGQVLSSNG 3356
Query: 134 -------HCRGCSQ--NGQTYGNGETFS-PDACTTCRCLTGAVQCQGPSCSELNCLE-SC 182
HC C GQ + G + PD C C CL G LNC + C
Sbjct: 3357 AICVQPGHC-SCLDLLTGQRHHPGARLARPDGCNHCTCLEG----------RLNCTDLPC 3405
Query: 183 TPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPAR--- 239
PG CP W EWT PCR G + R R CA CP P
Sbjct: 3406 PVPGGWCP---------WS---EWTMCSQPCR------GQTRSRSRACA--CPTPQHGGA 3445
Query: 240 PLPGTC-----------------CPV------------CDGCFLNGREHRSGE------P 264
P G CPV CD C G+ HRS P
Sbjct: 3446 PCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCL--GQSHRSRACSRPPTP 3503
Query: 265 VGSGDPC--SHCR---CANGSVQCEPL-----------PCPPVPCRH--PGKI--PGQ-- 302
G G PC +H + C S QC PCP C+ PG + PG
Sbjct: 3504 EG-GRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPR-SCQDLSPGSVCQPGSVG 3561
Query: 303 CCPVC---------DG---------CEYQ--------------GHQYQSQETFRLQE--R 328
C P C DG C+YQ G ++ S E+ E
Sbjct: 3562 CQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVT 3621
Query: 329 GLCVRCSCQAGEVSCEE-QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEP------ 381
G C C+C AG + C+E +CP + C GE+ P
Sbjct: 3622 GPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPA 3681
Query: 382 -DGRPCTACVCQDGVPKCGAVL--CPPAP-----CQHPTQPPG----------------- 416
R C+ VC++ G + C P C H TQ G
Sbjct: 3682 RQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF 3741
Query: 417 ----ACCPSCDSCTYHSQVYANGQNFTDADSP----------------CHACHCQDGTVT 456
AC C + G D P C C C G ++
Sbjct: 3742 QHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLS 3801
Query: 457 CSLVDC-----------PPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQ 505
CSL DC P C+R G G R C+L + P Q
Sbjct: 3802 CSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRT-RSRQCVL-----------TMPTLSGQ 3849
Query: 506 ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPC--- 562
CR C CP A + P T P G P P+ P
Sbjct: 3850 GCRGPRQDLECPSPDCPGAEGSTVEPVTGLPG---GWGPWSSWSPCSRSCTDPARPAWRS 3906
Query: 563 --RLC--RCLSGNV----QCLARRCVPLP-CPEPVLLPGECCPQCPAP-AGCPRP-GAAH 611
RLC C G+ C C LP CP P G C AP C R G
Sbjct: 3907 RTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQ 3966
Query: 612 ARHQEYFSPPGDPCRRCLCLDGSVSCQR---LPCPPAPCAHPRQGP---CCPSCDGCLYQ 665
R + PPG C + + +R L P P R P C SC G
Sbjct: 3967 QRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGG---- 4022
Query: 666 GKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC-PFPARGDC------------ 712
G+ S P+ G C + LC P P C
Sbjct: 4023 GQSLRSRSCSSPPSK--------NGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANR 4074
Query: 713 CPDCDGCEYLGESYLSNQEFPDPREPCNL-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHC 771
CP C L E + + + C C C G + + GC +P GHC
Sbjct: 4075 CPR--RCSDLQEGIVCQDD-----QVCQKGCRCPKGSLE------QDGGC----VPIGHC 4117
Query: 772 -CPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCF 830
C QG + A G D C+ C+CQ G + C +PCPP S +
Sbjct: 4118 DCTDAQGHSW-----APGSQHQD----ACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAW 4168
Query: 831 CPVCHSCLSQGREHQDGEEFEGPAGSCEW---CRCQAGQVS-CVRLQCPPLPCKLQVTER 886
P HSC +G++ + G W CR + Q C + CPPL
Sbjct: 4169 SPCSHSCGPRGQQSRFRSSTSG-----SWAPECREEQSQSQPCPQPSCPPL--------- 4214
Query: 887 GSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD 946
CL G W+ + C C C V C +C A
Sbjct: 4215 ---------CLQGTRSRTLGDSWLQGE--CQRCSCTPEGVICEDTECAVPEAWTLWSSWS 4263
Query: 947 CCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSL----RCHRRQCPSLVGC 1002
CP G Q C P PP L + ++ CP L+
Sbjct: 4264 DCPVSC-----------GGGNQVRTRACRAAA--PHHRSPPCLGPDTQTRQQPCPGLLEA 4310
Query: 1003 PPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDL---TWLCIHQACP 1059
P GP C +C L++ S G +A DP TC L T C CP
Sbjct: 4311 --CSWGPWGP--CSRSCGPGLASRS-GSCPCLMAKADP--TCNSTFLHLDTQGCYSGPCP 4363
Query: 1060 ELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVR-CQS 1118
E C S + C V Q HQG + G R C+ + G R C
Sbjct: 4364 E-ECVWSSWSSWTRCSCRVL--VQQRYRHQG-PASRGAR----AGAPCTRLDGHFRPCLI 4415
Query: 1119 QRCSPLSCGP------------------------DKAPALSPGSCCPR--------CLPR 1146
CS SC P P PG CP+ C+P
Sbjct: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIP- 4474
Query: 1147 PASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVA----WT 1202
P C + H + G + K+C +H T+ +G G+ W+
Sbjct: 4475 PEECNCW---HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTS--QGCQGLLPLSEWS 4529
Query: 1203 QEVAVLLGDMAVRLLQDGAVTVDGH----PVALPFLQEPLLYVELRGHTVILHAQPGLQV 1258
+ L ++ H P L PLL E H + L G
Sbjct: 4530 EWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRP- 4588
Query: 1259 LWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGP-EGLLLPSEAAFGNSWQVSEGL 1317
W G + + P S Q R C G Q L GP +P F W+ +E L
Sbjct: 4589 -WTGAPHL-CTAPLSQQ-RLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
Query: 1318 --------WPGRPCSAGREVDPC---------------------------RAAGYRARRE 1342
W C+ G PC R +
Sbjct: 4646 CGGGCREPWAQESCNGG----PCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCR 4701
Query: 1343 ANARC--GVL----KSSPFSRCHAVVPPE-------PFFAA--------CVYDLCAC--- 1378
RC G L + P S C +P P A CV + C
Sbjct: 4702 PGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQ 4761
Query: 1379 -----GPGSSADACLCDA----LEAYASHCRQAGVTPTWRGPTLCVVGCPLER------G 1423
GP S+ +C +E + + GV P T C L+ G
Sbjct: 4762 ECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPG 4821
Query: 1424 FVFDECGPPCPRTCFNQHIPLGELAAHCVR-PCVPGCQCPAGLVEHEAHCIPPEACPQVL 1482
V C CP C+ H+ G + CV+ PC PGC CP G + H C+PP ACP
Sbjct: 4822 QVLSACATSCPCLCW--HLQPGAI---CVQEPCQPGCGCPGGQLLHNGTCVPPTACP--C 4874
Query: 1483 LTGDQPLGARPSPSREPQETP 1503
P G + + QE P
Sbjct: 4875 TQHSLPWGLTLTLEEQAQELP 4895
Score = 149 bits (375), Expect = 3e-35
Identities = 304/1320 (23%), Positives = 404/1320 (30%), Gaps = 384/1320 (29%)
Query: 88 ECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGA----AHCGPQAHLPHCRGCSQNGQ 143
+CH C L G C C G A C P++ P C +GQ
Sbjct: 2897 QCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCP----CQLHGQ 2952
Query: 144 TYGNGETFSPDACTTCRCLT---------------------------------------- 163
Y +G D+C C C++
Sbjct: 2953 LYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAG 3012
Query: 164 -------GAVQCQGPSC-SELNCLESCTPPG------ECCPICCTEGGSHWEHG-----Q 204
G +CQGP+ +E L C PG C + C G + G
Sbjct: 3013 TAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLM 3072
Query: 205 EWTTPG-DPCR-----ICRCLEGHIQCRQ--RECASL---------------CPYPARPL 241
E++T G PC +C + + C Q CA L CP L
Sbjct: 3073 EFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLL 3132
Query: 242 PGTCCPVCD-GCFLNGREHRSGEPVGSGDPCSHCRCANGSV-QCEPLPCPP-VPCRHPGK 298
C P D C G + G V PC +C C +G + C PC P P
Sbjct: 3133 NNVCVPTQDCPCAHEGHLYPPGSTVVR--PCENCSCVSGLIANCSSWPCAEGEPTWSPWT 3190
Query: 299 IPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPAS 358
QC C H++ C R S V P LPA+
Sbjct: 3191 PWSQCSASCGPARCHRHRF-------------CAR--------SPSAVPSTVAPLPLPAT 3229
Query: 359 GRQLCPA-------CELDGEEFAEGVQWEPDGRPCTAC--VCQDGVPKCGAVLCPPAP-- 407
LC C L G + A G W P G P + C C G+ P P
Sbjct: 3230 PTPLCSGPEAEEEPCLLQGCDRAGG--WGPWG-PWSHCSRSCGGGLRSRTRACDQPPPQG 3286
Query: 408 ----CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPC-HAC--------HCQDGT 454
C+ P + G C + C + G ++ PC +C CQ G
Sbjct: 3287 LGDYCEGP-RAQGEVCQAL-PCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGC 3344
Query: 455 VTCSLVDCPPTTCARPQSG----PGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQ 510
CPP PG C C D +L + G + P D C C C
Sbjct: 3345 Y------CPPGQVLSSNGAICVQPGHC--SCLD-LLTGQRHHPGARLARP-DGCNHCTCL 3394
Query: 511 EGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSG 570
EG +C PC P+PG CP +++ S PCR G
Sbjct: 3395 EGRLNCTDLPC-------PVPGGWCP---------------WSEWTMCSQPCR------G 3426
Query: 571 NVQCLARRCVPLPCPEPVLLPGECCPQ------------CPAPAGCPRPGAAHARHQEYF 618
+ +R C CP P C + CP+ A CP GA +
Sbjct: 3427 QTRSRSRACA---CPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGA--------W 3475
Query: 619 SP--PGDPCRRCLCLD-GSVSCQRLPCP----PAPCAHPRQGPC---CPSCDGCLYQGKE 668
P P PC CL S +C R P P P P H + PC C C
Sbjct: 3476 GPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSL 3535
Query: 669 FASGERFPSPTAACHL---CLCWEGSVSCEPKACAPALCPFPARGDCCPDCD-GCEY--- 721
G+ P P + L +C GSV C+P C L G C P C+Y
Sbjct: 3536 HPCGQ--PCPRSCQDLSPGSVCQPGSVGCQP-TCGCPLGQLSQDGLCVPPAHCRCQYQPG 3592
Query: 722 ----------LGESYLSNQEFPDPRE----PCNLCTCLGGFVTCGRRP-CEPPGCSHPLI 766
S S+ E +P E PC+ CTC+ G + C P C PG
Sbjct: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
Query: 767 PSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP 826
P C +C G GE L S RC + PCP P
Sbjct: 3653 PWEDCSVSCGG----------GEQL---------------RSRRCARPPCPG---PARQS 3684
Query: 827 GPCFCPVCHSC-LSQGREHQDGEEFEGPAGSC---------------EWCRCQAG----Q 866
C VC GR +++ + EG SC E C C G +
Sbjct: 3685 RTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHR 3744
Query: 867 VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVV 926
++CV+ +CP + + E G+ L G+E G ++C +C C G +
Sbjct: 3745 LACVQ-ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTL---RTSCGNCSCAHGKL 3800
Query: 927 TCARIQCISS----------------------------------------CAQPRQGPHD 946
+C+ C + C PRQ
Sbjct: 3801 SCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLEC 3860
Query: 947 CCPQCSDCEHEGRKYEPGESFQPG------ADPCEVCICEPQPEGPPSLRCHRRQCPSLV 1000
P C EG EP G PC +P P+ R R C L
Sbjct: 3861 PSPDCPGA--EGSTVEPVTGLPGGWGPWSSWSPCSRSCTDP---ARPAWRSRTRLC--LA 3913
Query: 1001 GC---PPSQLLPPGPQHC-----CPTCAEALSNCSEGLLGSELAPPDPC-YTCQCQDLTW 1051
C P Q P C CP NCS + AP +PC +C
Sbjct: 3914 NCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCS----WTSWAPWEPCSRSCGVGQQRR 3969
Query: 1052 LCIHQA-------CPELSCPLSERHTPPGSCCPVCR-----APTQSCVHQGREVASGERW 1099
L ++ CP + ER CPV +P C R G+
Sbjct: 3970 LRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWC---DRSCGGGQSL 4026
Query: 1100 TVDTCTSCSCMAGTVRCQSQR-----CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
+C+S G C +R C+P+ C + +C RC PR S + G
Sbjct: 4027 RSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRC-PRRCSDLQEG 4085
Score = 147 bits (370), Expect = 1e-34
Identities = 300/1254 (23%), Positives = 380/1254 (30%), Gaps = 326/1254 (25%)
Query: 84 LESCECHPAS--PQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGP------------Q 129
L C P S P G WP G + C+ CVC+ G C P
Sbjct: 2664 LHDTRCLPLSECPCLVGEELKWP-GVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWS 2722
Query: 130 AHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQG-------------PSCSEL 176
+ P R C + + P A C + QG P S
Sbjct: 2723 SWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWS 2782
Query: 177 NCLESCTPPG----------------------------ECCPICCTEGGSHWEHGQEWTT 208
+C +SC PG C P C S W W+T
Sbjct: 2783 SCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPV-PSIWGLWAPWST 2841
Query: 209 PGDPCRICRCLEGHIQCRQRECASL------CPYPARPLPGTCCPVCDGCFLNGREHRSG 262
PC +G IQ R R C+SL CP P C RS
Sbjct: 2842 CSAPC------DGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSA 2895
Query: 263 EPV-GSGDPCSH-CRCANGSVQCEPL-----PCPPVPCRHPGK-IPGQCCPVCDGCEYQG 314
E G PC C ++C CPP H +P CP C+ G
Sbjct: 2896 EQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCP----CQLHG 2951
Query: 315 HQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCP-ACELD-GEE 372
Y S RL C C+C +G+++C + CPV P + LC +C +
Sbjct: 2952 QLYASGAMARLDS---CNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRR 3008
Query: 373 FAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSC--TYHSQ 430
F G P + P A C PC P G P C Y ++
Sbjct: 3009 FRAGT-----APPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGYRNR 3063
Query: 431 VYANGQNFTDADS----PCHA------------CHCQDGTVTCSLVDCPPTTCARPQSGP 474
+ ++ + + PC C G +C+ + P T P
Sbjct: 3064 TRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGT--NQTCHP 3121
Query: 475 GQCCPR--------------CPDCILEEEVFVDGESFSHPRDPCQECRCQEG-HAHCQPR 519
G CP CP C E ++ G + PC+ C C G A+C
Sbjct: 3122 GCHCPSGMLLLNNVCVPTQDCP-CAHEGHLYPPGSTVVR---PCENCSCVSGLIANCSSW 3177
Query: 520 PCPRA-PCAHP-LPGTCCPNDCSG--------CAFGGKEYPSG-ADFPHPSDPCRLCRCL 568
PC P P P + C C CA PS A P P+ P LC
Sbjct: 3178 PCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLC--- 3234
Query: 569 SGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAG---------CPRP--GAAHARHQEY 617
SG P EP LL G C G C R G +R +
Sbjct: 3235 SG----------PEAEEEPCLLQG-----CDRAGGWGPWGPWSHCSRSCGGGLRSRTRAC 3279
Query: 618 FSPP----GDPCRRCLCLDGSVSCQRLPCPPAPCA---HPRQGPCCPSCDGCLYQGKEFA 670
PP GD C G V CQ LPCP C PC P C
Sbjct: 3280 DQPPPQGLGDYCEGPRA-QGEV-CQALPCPVTNCTAIEGAEYSPCGPPC----------- 3326
Query: 671 SGERFPSPTAACHLCLC-WEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYL----GES 725
P + L C W C+P P + G C C L G+
Sbjct: 3327 -------PRSCDDLVHCVWR----CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQR 3375
Query: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPG----------CSHPL-----IPSGH 770
+ P + CN CTCL G + C PC PG CS P S
Sbjct: 3376 HHPGARLARP-DGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRA 3434
Query: 771 C-CPTCQ-------------GCRYHGVTTASGETLP-----DPLDP--TCSLCTCQEGSM 809
C CPT Q G ++ S T P P P C +C Q
Sbjct: 3435 CACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRS 3494
Query: 810 R-CQKKPCPPALCPHP-----------------------SPGPCFCPVCHSC--LSQGRE 843
R C + P P P P S PC P SC LS G
Sbjct: 3495 RACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSV 3554
Query: 844 HQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEH 903
Q G G C C GQ+S L PP C+ Q P G + +
Sbjct: 3555 CQPGS-----VGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ------PGAMG-IPENQSR 3602
Query: 904 PEGSRWVPPDS---------ACSSCVCHEGVVTCARI-QCISSCAQPRQGP-HDCCPQCS 952
GSR+ +S C +C C G++ C + C GP DC C
Sbjct: 3603 SAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCG 3662
Query: 953 DCEHE-----GRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQL 1007
E R PG + Q +VC + G P+ R + R+C GCP S
Sbjct: 3663 GGEQLRSRRCARPPCPGPARQSRTCSTQVC----REAGCPAGRLY-RECQPGEGCPFSCA 3717
Query: 1008 LPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSE 1067
C E +C EG LA C C WL EL + +
Sbjct: 3718 HVTQQVGCFSEGCEEGCHCPEGTFQHRLA---CVQECPCVLTAWL-----LQELGATIGD 3769
Query: 1068 RHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRC 1121
P G G E+ SG+ +C +CSC G + C C
Sbjct: 3770 PGQPLG---------------PGDELDSGQTLRT-SCGNCSCAHGKLSCSLDDC 3807
Score = 144 bits (363), Expect = 6e-34
Identities = 302/1257 (24%), Positives = 386/1257 (30%), Gaps = 326/1257 (25%)
Query: 77 LQTRVRQLESCECHPA--SPQCWGLGRAWPEGARWEPDACTACVCQDGAAHC----GPQA 130
LQ R L SC P P C +W A WEP + + V Q GP
Sbjct: 3921 LQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGG 3980
Query: 131 H-------------LPHCRGCSQNG------------QTYGNGETFSPDACTTCRCLTGA 165
H + R C G ++ G G++ +C++ G
Sbjct: 3981 HWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGG 4040
Query: 166 VQCQGPSCSELNCLESCTP-PGEC-CPICCTEGGSHWEHGQEWTTPGDPC-RICRCLEGH 222
C G E + C P P E CP G E T + C R C L+
Sbjct: 4041 APCAG----ERHQARLCNPMPCEAGCPA-----------GMEVVTCANRCPRRCSDLQEG 4085
Query: 223 IQCR-----QRECASLCPYPARPLPGTCCPV--CDGCFLNGREHRSGEPVGSGDPCSHCR 275
I C+ Q+ C CP + G C P+ CD G G D C++C
Sbjct: 4086 IVCQDDQVCQKGCR--CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQ--HQDACNNCS 4141
Query: 276 CANGSVQCEPLPCPPV------------PCRHPGKIPGQ--------------------- 302
C G + C PCPP PC H GQ
Sbjct: 4142 CQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQS 4201
Query: 303 ---------CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPC 353
C P+C QG + ++ LQ G C RCSC V CE+ EC V
Sbjct: 4202 QSQPCPQPSCPPLC----LQGTRSRTLGDSWLQ--GECQRCSCTPEGVICEDTECAVPEA 4255
Query: 354 ALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPA-----PC 408
S CP G + R C A P C L P PC
Sbjct: 4256 WTLWSSWSDCPVSCGGGNQVRT--------RACRAAAPHHRSPPC---LGPDTQTRQQPC 4304
Query: 409 QHPTQ-----PPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCP 463
+ P G C SC S+ + AD C++ T C CP
Sbjct: 4305 PGLLEACSWGPWGPCSRSCGP-GLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCP 4363
Query: 464 PTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAH-CQPRPCP 522
S +C R +L ++ + S C +GH C C
Sbjct: 4364 EECVWSSWSSWTRCSCR----VLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCS 4419
Query: 523 RAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRL-CRCLSGNVQCLARRCVP 581
C P C + C+G + D P PC+ C C G ++ A C+P
Sbjct: 4420 EDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLP----PCQPGCYCPKGLLE-QAGGCIP 4474
Query: 582 LPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDP----CRRCLCLDGSVSC 637
P EC C AA A PGD C+ C C G + C
Sbjct: 4475 ---------PEEC--------NCWHTSAAGAGMT---LAPGDRLQLGCKECECRRGELHC 4514
Query: 638 QRLPCPP----------APCAHPRQGPCCPSCDGCLYQGKEFASGERFP------SPTAA 681
C +PC GPC P L A E + SPT A
Sbjct: 4515 TSQGCQGLLPLSEWSEWSPC-----GPCLPP--SALAPASRTALEEHWLRDPTGLSPTLA 4567
Query: 682 CHLC-------LCWEGSVSCEPKACAPALCPFP-ARGDCCPDCDGCEYLGESYLSNQEFP 733
L LC + + P AP LC P ++ CPD C + L
Sbjct: 4568 PLLASEQHRHRLCLDPATG-RPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWG---- 4622
Query: 734 DPREPCNLCTCLGGF--------VTCG---RRPCEPPGCSHPLIPSGHCCPTCQGCRYHG 782
P PC + C GGF CG R P C+ G CP C+
Sbjct: 4623 -PWSPCQV-PCSGGFRLRWREAEALCGGGCREPWAQESCN------GGPCPECEA--QDT 4672
Query: 783 VTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPAL-CPHPS---PGPCFCPV--CHS 836
V T D + C ++C + PC P CP G C P+ C
Sbjct: 4673 VFTL------DCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCV-PISSCRC 4725
Query: 837 CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGC 896
L + + C+ C C + C +CP L + SC C G
Sbjct: 4726 GLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLG---PWSAWSSCSAPCGGG 4782
Query: 897 LAHGEEHPEGSRWVPPDSA--------CSSCVCHEGVVTCARIQCISSCAQPRQGPHDCC 948
EG V P A C+ C E C Q +S+CA C
Sbjct: 4783 TMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE----CPPGQVLSACATS-------C 4831
Query: 949 PQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEG---PPSLRCHRRQCPSLVGCP-- 1003
P C H QPGA +C+ EP G P H C CP
Sbjct: 4832 PCL--CWH----------LQPGA----ICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCT 4875
Query: 1004 --------------PSQLLPPGP--QHCCPTCAEALSNCSEGLLGSELA----PPDPCYT 1043
+Q LPPG C C C G L PP +
Sbjct: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCV-----CHGGAFSCSLVDCQVPPGETWQ 4930
Query: 1044 CQCQDLTWLCIHQACPELS-----------------CPLSERHTPPGSCCPVCRAPTQSC 1086
LC Q C E++ C + G C P C
Sbjct: 4931 QVAPGELGLC-EQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHC---EC 4986
Query: 1087 VHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143
H GR G W + C SC C++G C +Q CSPL+C + L PGSCCP C
Sbjct: 4987 WHLGRPHLPGSEWQ-EACESCLCLSGRPVC-TQHCSPLTCAQGEEMVLEPGSCCPSC 5041
Score = 134 bits (337), Expect = 7e-31
Identities = 289/1207 (23%), Positives = 375/1207 (31%), Gaps = 305/1207 (25%)
Query: 106 GARWEPDACTACVCQDGAAHCGPQAHLPHC-RGCSQNGQTYGNGETFSPDACTTCRCLTG 164
G E + C C D A GP HC R C G G AC
Sbjct: 3236 GPEAEEEPCLLQGC-DRAGGWGPWGPWSHCSRSC-------GGGLRSRTRACDQPPPQGL 3287
Query: 165 AVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQ 224
C+GP C P C I G E++ G PC R + +
Sbjct: 3288 GDYCEGPRAQGEVCQALPCPVTNCTAI----------EGAEYSPCGPPCP--RSCDDLVH 3335
Query: 225 CRQR-ECASLCPYPARPLP--GTCCPVCDGC----FLNGREHRSGEPVGSGDPCSHCRCA 277
C R + CP P + L G C C L G+ H G + D C+HC C
Sbjct: 3336 CVWRCQPGCYCP-PGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCL 3394
Query: 278 NGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSC- 336
G + C LPCP +PG CP + + R Q R C+C
Sbjct: 3395 EGRLNCTDLPCP---------VPGGWCPWSEWT-------MCSQPCRGQTRSRSRACACP 3438
Query: 337 -----------QAGEVSCEEQECPVTPCALPASGRQLCPA---CELDGEEFAEGVQWEPD 382
+AGE + Q R+ CP+ C +DG W P
Sbjct: 3439 TPQHGGAPCTGEAGEAGAQHQ-------------REACPSYATCPVDG-------AWGPW 3478
Query: 383 G--RPCTACVCQDGVPK-CGAVLCP----PAPCQHPTQPPGACCPSCDSCTYHSQVYANG 435
G PC C+ Q + C P P P H P C + CT G
Sbjct: 3479 GPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRP--CQENSTQCT----DCGGG 3532
Query: 436 QNFTDADSPC-HACH-------CQDGTVTCSLVDCPPTTCARPQ-SGPGQCCP----RC- 481
Q+ PC +C CQ G+V C P C Q S G C P RC
Sbjct: 3533 QSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQ----PTCGCPLGQLSQDGLCVPPAHCRCQ 3588
Query: 482 --PDC--ILEEEVFVDGESFS-----HPRD----PCQECRCQEGHAHCQPRPCPRAPCAH 528
P I E + G FS P + PC C C G CQ P
Sbjct: 3589 YQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVP-------- 3640
Query: 529 PLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 588
CP+ ++G P + C + G Q +RRC PCP P
Sbjct: 3641 -----DCPDPGVWSSWG------------PWEDCSV--SCGGGEQLRSRRCARPPCPGPA 3681
Query: 589 LLPGECCPQCPAPAGCP--------RPG------AAHARHQEYFSPPGDPCRR-CLCLDG 633
C Q AGCP +PG AH Q G C C C +G
Sbjct: 3682 RQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEG--CEEGCHCPEG 3739
Query: 634 S----VSC-QRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCW 688
+ ++C Q PC G L G E SG+ +C C C
Sbjct: 3740 TFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTL---RTSCGNCSCA 3796
Query: 689 EGSVSCEPKACAPA---LCPFPARGDCCPDCDGCE--------YLGESYLSNQEFPDPRE 737
G +SC C A P+ G C C G L LS Q PR+
Sbjct: 3797 HGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQ 3856
Query: 738 --PCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTC-----QGCRYHGVTTASGET 790
C C G + PG P C +C R + T
Sbjct: 3857 DLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCT 3916
Query: 791 LPDPL-DPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEE 849
+ DPL + C+L +C E + C C C S P + P SC +
Sbjct: 3917 MGDPLQERPCNLPSCTELPV-CPGPGCGAGNCSWTSWAP-WEPCSRSCGVGQQRRLRAYR 3974
Query: 850 FEGPAGSCEWC---RCQAGQVSCVRLQCPPLPCKLQVTERGSCCP---------RCRGCL 897
GP G WC + L+ P+P S C R R C
Sbjct: 3975 PPGPGG--HWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCS 4032
Query: 898 A----------HGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQG---- 943
+ GE H +R P + C VVTCA +C C+ ++G
Sbjct: 4033 SPPSKNGGAPCAGERHQ--ARLCNPMPCEAGCPAGMEVVTCAN-RCPRRCSDLQEGIVCQ 4089
Query: 944 -----PHDC-CPQ--------------CSDCEHEGRKYEPGESFQPGADPCEVCICEPQP 983
C CP+ C + +G + PG Q D C C C+
Sbjct: 4090 DDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQ---DACNNCSCQ--- 4143
Query: 984 EGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCS-----EGLLGSELAPP 1038
L C + CP P HC + A S CS G +
Sbjct: 4144 --AGQLSCTAQPCPP-------------PTHCAWSHWSAWSPCSHSCGPRGQQSRFRSST 4188
Query: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
+ +C++ Q CP+ SCP P+C T R G+
Sbjct: 4189 SGSWAPECREEQ--SQSQPCPQPSCP------------PLCLQGT-------RSRTLGDS 4227
Query: 1099 WTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCP-RC----LPRPASCMAF 1153
W C CSC V C+ C+ P+ S S CP C R +C A
Sbjct: 4228 WLQGECQRCSCTPEGVICEDTECAV----PEAWTLWSSWSDCPVSCGGGNQVRTRACRA- 4282
Query: 1154 GDPHYRT 1160
PH+R+
Sbjct: 4283 AAPHHRS 4289
Score = 109 bits (273), Expect = 2e-23
Identities = 244/1033 (23%), Positives = 311/1033 (30%), Gaps = 300/1033 (29%)
Query: 85 ESCECHPASPQCWGLGRAWPE-------GARWEPDACTACVCQDGAAHC-GP--QAHLPH 134
E EC A P+ W L +W + G + AC A + C GP Q
Sbjct: 4246 EDTEC--AVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQP 4303
Query: 135 CRG------------CSQN-----GQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELN 177
C G CS++ G+ A TC + QG C
Sbjct: 4304 CPGLLEACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQG--CYSGP 4361
Query: 178 CLESCTPPG-----EC-CPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQ------C 225
C E C C C + + H G PC L+GH + C
Sbjct: 4362 CPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTR---LDGHFRPCLISNC 4418
Query: 226 RQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRCANGSVQCE 284
+ C P+ C +C H S + PC C C G ++
Sbjct: 4419 SEDSCTP--PFEFHACGSPCAGLC-------ATHLSHQLCQDLPPCQPGCYCPKGLLEQA 4469
Query: 285 PLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE 344
PP C C G RLQ C C C+ GE+ C
Sbjct: 4470 GGCIPPEECN------------CWHTSAAGAGMTLAPGDRLQLG--CKECECRRGELHCT 4515
Query: 345 EQEC-------------PVTPCALPASGRQLCPACELDGEE--FAEGVQWEPDGRPCTAC 389
Q C P PC P++ L PA EE + P P A
Sbjct: 4516 SQGCQGLLPLSEWSEWSPCGPCLPPSA---LAPASRTALEEHWLRDPTGLSPTLAPLLAS 4572
Query: 390 ------VCQD---GVPKCGAV-LCP-PAPCQHPTQPPGACCPSCDSCTYHS----QVYAN 434
+C D G P GA LC P Q PGAC SC + QV +
Sbjct: 4573 EQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCS 4632
Query: 435 GQ---NFTDADS------------------PCHACHCQDGTVTCSLVDCPPTTCA----R 469
G + +A++ PC C QD T + P +CA R
Sbjct: 4633 GGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDR 4692
Query: 470 PQSGPGQCCP--RCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
Q G C P RCP L + DG P CRC P A +
Sbjct: 4693 VQCLQGPCRPGCRCPPGQLVQ----DGRCV-----PISSCRCG----------LPSANAS 4733
Query: 528 HPL-PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPE 586
L P DC C C++ ++ C + C
Sbjct: 4734 WELAPAQAVQLDCQNCT-----------------------CVNESLVCPHQEC------- 4763
Query: 587 PVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAP 646
PVL P C AP G G RH+ PG + + C PCP P
Sbjct: 4764 PVLGPWSAWSSCSAPCG----GGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECP 4819
Query: 647 CAHPRQ--GPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCW--EGSVSCEPKACAPA 702
P Q C SC CLCW + C + C P
Sbjct: 4820 ---PGQVLSACATSCP------------------------CLCWHLQPGAICVQEPCQPG 4852
Query: 703 L-CP---FPARGDCCPDCDGCEYLGESY-----LSNQEFPDPREP-------CNLCTCLG 746
CP G C P C S L+ +E P C C C G
Sbjct: 4853 CGCPGGQLLHNGTCVPPT-ACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHG 4911
Query: 747 GFVTCGRRPCE-PPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQ 805
G +C C+ PPG + + G Q C T +T + S C CQ
Sbjct: 4912 GAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNAT----KTQSNCSSARASGCVCQ 4967
Query: 806 EGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAG 865
G R Q PC P C C GR H G E++ +CE C C +G
Sbjct: 4968 PGHFRSQAGPCVPE-------DHC------ECWHLGRPHLPGSEWQE---ACESCLCLSG 5011
Query: 866 QVSCVRLQCPPLPC---KLQVTERGSCCPRCRGCLAHGEEHPE----------------- 905
+ C + C PL C + V E GSCCP CR A E+ P
Sbjct: 5012 RPVCTQ-HCSPLTCAQGEEMVLEPGSCCPSCRR-EAPEEQSPSCQLLTELRNFTKGTCYL 5069
Query: 906 -------------GSRWVPPD-----SACSSCVCH---EGVVTCARIQCISSCAQPRQGP 944
S V P+ S C C E V ++C+ +P P
Sbjct: 5070 DQVEVSYCSGYCPSSTHVMPEEPYLQSQCDCCSYRLDPESPVRILNLRCLGGHTEPVVLP 5129
Query: 945 --HDCCPQCSDCE 955
H C QCS C+
Sbjct: 5130 VIHSC--QCSSCQ 5140
Score = 109 bits (272), Expect = 2e-23
Identities = 259/1092 (23%), Positives = 332/1092 (30%), Gaps = 292/1092 (26%)
Query: 209 PGDPCRICRCLEGHIQCRQRECASL---CPYPARPLPGTCCPVCDGCFLNGREHRSGEPV 265
PG P C + C EC S C G+ C C L P
Sbjct: 2455 PGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVL--------APW 2506
Query: 266 GSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETF-- 323
CS + Q + L PP +PG CP +++SQ F
Sbjct: 2507 SVWSSCSRSCGLGLTFQRQELLRPP--------LPGGSCP--------RDRFRSQSCFVQ 2550
Query: 324 ---------RLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFA 374
+ G C SC G S ++ C P P +G CP
Sbjct: 2551 ACPVAGAWAMWEAWGPC-SVSCGGGHQS-RQRSCVDPP---PKNGGAPCPGAS------- 2598
Query: 375 EGVQWEPDGRPCTACVCQDGVP-KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
+ PC C G + G V CQ PP C PSC
Sbjct: 2599 ------QERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPP--CPPSCLD--------- 2641
Query: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP--RCPDCILEEEVF 491
A+ C HC +G CPP +C P CP C++ EE+
Sbjct: 2642 -----PKANRSCSG-HCVEGC------RCPPGLLLHDT----RCLPLSECP-CLVGEELK 2684
Query: 492 VDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPS 551
G SF C +C C++G CQP CP PC + P D S C G +
Sbjct: 2685 WPGVSFLLGN--CSQCVCEKGELLCQPGGCP-LPCGWSAWSSWAPCDRS-CGSGVR---- 2736
Query: 552 GADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCP----------EPVLLPGECCPQCPAP 601
A F PS+P G C R C P C C AP
Sbjct: 2737 -ARFRSPSNP----PAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAP 2791
Query: 602 AG----------CPRPG----AAHARHQEYFSPPGDPCRRCLCL-----------DGSV- 635
G CP PG A +E SPP P L DG +
Sbjct: 2792 GGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQ 2851
Query: 636 ----SCQRLPCPPAPCAHPRQ-------GPCCPSC-DGCLYQGKEFASGERFPSPTAACH 683
SC L C P PC C + L++ E E P P
Sbjct: 2852 TRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCP----R 2907
Query: 684 LCLCWEGSVSCEPKACAPALCP---FPARGDCCPDCD-GCEYLGESYLSNQEFPDPREPC 739
LCL + C CP F C P C+ G+ Y S + C
Sbjct: 2908 LCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA--MARLDSC 2965
Query: 740 NLCTCLGGFVTCGRRPCEPPGCS-HPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDP 797
N CTC+ G + C C P C P C +C G R +G P
Sbjct: 2966 NNCTCVSGKMACTSERC-PVACGWSPWTLWSLCSCSCNVGIRRR---FRAGTAPPAAFGG 3021
Query: 798 TCSLCTCQEGSMR---CQKKPCPPALCPHPSPGPCFCPVCHSCLSQGR-EHQDGEEFE-- 851
CQ +M C +PCP PC P ++ R + EF
Sbjct: 3022 ----AECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTC 3077
Query: 852 ------GPA-GSC----EWCRCQAGQVSCVRLQC---------PPLPCKLQVTERGSCCP 891
GP G C +W C G SC L P C + + C
Sbjct: 3078 GLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCV 3137
Query: 892 RCRGC-LAH-GEEHPEGSRWVPPDSACSSCVCHEGVVT------CAR-----------IQ 932
+ C AH G +P GS V P C +C C G++ CA Q
Sbjct: 3138 PTQDCPCAHEGHLYPPGSTVVRP---CENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQ 3194
Query: 933 CISSCAQPRQGPHDCC---------------------PQCSDCEHEGRKYEPGESFQPGA 971
C +SC R H C P CS E E
Sbjct: 3195 CSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAE-------------E 3241
Query: 972 DPCEVCICEPQ----PEGPPS---------LRCHRRQCPSLVGCPPSQLL------PPGP 1012
+PC + C+ P GP S LR R C PP Q L P
Sbjct: 3242 EPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQ----PPPQGLGDYCEGPRAQ 3297
Query: 1013 QHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPP 1072
C ++NC+ + G+E +P P C DL C+ + P CP + +
Sbjct: 3298 GEVCQALPCPVTNCT-AIEGAEYSPCGPPCPRSCDDLVH-CVWRCQPGCYCPPGQVLSSN 3355
Query: 1073 GSCCPVCRAPTQSCVH--QGREVASGERWT-VDTCTSCSCMAGTVRCQSQRCSPLSCGPD 1129
G+ C + SC+ G+ G R D C C+C+ G + C C
Sbjct: 3356 GAIC--VQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP------- 3406
Query: 1130 KAPALSPGSCCP 1141
PG CP
Sbjct: 3407 -----VPGGWCP 3413
Score = 105 bits (262), Expect = 3e-22
Identities = 234/927 (25%), Positives = 284/927 (30%), Gaps = 242/927 (26%)
Query: 308 DGCEYQGH--QYQSQETFRLQERGLCVRCSC-QAGEVSCEEQE------CPVTPCA---- 354
D C GH +++SQE LQ G V +C +C EQ C V C
Sbjct: 1254 DECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCF 1313
Query: 355 -----LPASGRQLCPA---CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPA 406
L G L PA CE F G + D C C CQ+G CG
Sbjct: 1314 CPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKD---CGNCTCQEGQWHCGG---DGG 1367
Query: 407 PCQH--PTQPPG-ACCPSCDSCTYHSQVYANGQNFTDA--DSPCHACHCQDGTVTCSLVD 461
C+ P G A C C H + N + D + C A C +G +TCS
Sbjct: 1368 HCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGH 1427
Query: 462 CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPC 521
C P C R DC G+ P PC + C P
Sbjct: 1428 CLPLALL---------CDRQDDC---------GDGTDEPSYPCPQGLLACADGRCLP--- 1466
Query: 522 PRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVP 581
P C +P D C+ G V C+ C+
Sbjct: 1467 ---------PALLCDG-----------HPDCLDAADEESCLGQVTCVPGEVSCVDGTCLG 1506
Query: 582 L--------PCPEPVLL-PGEC-CPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCL 631
CP+ PG C P P P PG + PG L
Sbjct: 1507 AIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPS----------PGS-------L 1549
Query: 632 DGSVSCQRLPCPPAPCA----HPRQGPCCPS---CDGCLYQGKEFASG--ERFPSPTAAC 682
D + S P PC G C P CD Q ++ A G ER A
Sbjct: 1550 DTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCD----QEEDCADGSDERGCGGPCAP 1605
Query: 683 HLCLCWEGSVSCEPKACAPALCPFPARGDCCPD-CDGCEYLGESYLSNQEFPDPREPCNL 741
H C G P+ + P D PD C G LG + P P C
Sbjct: 1606 HHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACGGLPALGGP--NRTGLPCPEYTCPN 1663
Query: 742 CTCLGGFVTCGRRP-CEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCS 800
TC+G + C +P C PG P P QGC G + G P TC
Sbjct: 1664 GTCIGFQLVCDGQPDCGRPGQVGP-------SPEEQGCGAWGPWSPWG-----PCSRTCG 1711
Query: 801 LCTCQEGSMRCQK------KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE-EFEGP 853
Q S RC + CP P CF C DGE P
Sbjct: 1712 PWG-QGRSRRCSPLGLLVLQNCPG---PEHQSQACFTAACPV---------DGEWSTWSP 1758
Query: 854 AGSC-EWCR-CQAGQVSCVRLQ-----CPPLPCKLQVTERGSCCPR--CRGCLAHGE--- 901
C E CR Q C Q C LP L T + CP+ C GE
Sbjct: 1759 WSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMF 1818
Query: 902 ----------EHPEGSRWVPPDSACSS--CVCHEGVVTCARIQCISSCAQPRQGPHDCCP 949
+ G PPD C S C C EG V + C+ PRQ CP
Sbjct: 1819 QPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCV----WPRQ-----CP 1869
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
C +G +Y PG+ + AD C++CIC+ +G P RC
Sbjct: 1870 ----CLVDGARYWPGQRIK--AD-CQLCICQ---DGRPR-RCRLN--------------- 1903
Query: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
P CA S L P C Q + W S S
Sbjct: 1904 -------PDCAVDCGWSSWSPWAKCLGP------CGSQSIQW----------SFRSSNNP 1940
Query: 1070 TPPG---SCCPVCRA-------PTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQ 1119
P G C + R P + C HQG+ GERW C C C+ S
Sbjct: 1941 RPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSP 2000
Query: 1120 RCSPLSCGPDKAPALSPG-SCCPRCLP 1145
C SC G SCC LP
Sbjct: 2001 YCPLGSCPQGWVLVEGTGESCCHCALP 2027
Score = 93.6 bits (231), Expect = 1e-18
Identities = 199/874 (22%), Positives = 271/874 (31%), Gaps = 223/874 (25%)
Query: 91 PASPQC-WGLGRAWPEGARWEPDACTACVCQDGAAHCGP-----QAHLPHCRG----CSQ 140
PAS C WG ++P G+ + D C C CQ+G HCG + +P C C +
Sbjct: 1328 PASCPCEWGRN-SFPPGSVLQKD-CGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQE 1385
Query: 141 NGQTYGN----------GETFSPDACTTCRCLTGAVQCQGPSCSEL--------NCLESC 182
NG + G+ + C C G + C C L +C +
Sbjct: 1386 NGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGT 1445
Query: 183 TPPGECCP---ICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPAR 239
P CP + C +G P +C +GH C C
Sbjct: 1446 DEPSYPCPQGLLACADGRCL-----------PPALLC---DGHPDCLDAADEESCLGQVT 1491
Query: 240 PLPGTCCPVCDGCFLNGREHRSGE---PVGSGDPCSHCRCANGSVQCEPLPCPPVP--CR 294
+PG V DG L + G P G+ + HC PLP P P
Sbjct: 1492 CVPGEVSCV-DGTCLGAIQLCDGVWDCPDGADEGPGHC----------PLPSLPTPPAST 1540
Query: 295 HPGKIPGQC------------CPVCDGCEYQ-GHQYQSQETFRLQERGLCVRCSCQAGEV 341
PG PG P C E++ G + +R + C S
Sbjct: 1541 LPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGS------ 1594
Query: 342 SCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAV 401
+E+ C PCA + P C + E+ +GV+ PDG C G+P G
Sbjct: 1595 --DERGCG-GPCAPHHAPCARGPHC-VSPEQLCDGVRQCPDGSDEGPDAC-GGLPALGGP 1649
Query: 402 LCPPAPCQHPTQPPGAC------CPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTV 455
PC T P G C C C QV + + + C A
Sbjct: 1650 NRTGLPCPEYTCPNGTCIGFQLVCDGQPDCGRPGQVGPSPE-----EQGCGAWGPWSPWG 1704
Query: 456 TCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAH 515
CS TC G + C +L Q C E +
Sbjct: 1705 PCS------RTCGPWGQGRSRRCSPLGLLVL------------------QNCPGPEHQSQ 1740
Query: 516 -CQPRPCP-RAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQ 573
C CP + P + C C G ++ S P + R C L G +
Sbjct: 1741 ACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHS------PQNGGRTCAALPGGLH 1794
Query: 574 CLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRR--CLCL 631
+ PCP+ C + P P + PP PC C C
Sbjct: 1795 STRQ---TKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCP 1851
Query: 632 DGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS 691
+G V C PRQ CP CL G + G+R A C LC+C +G
Sbjct: 1852 EGQVLGSE-----GWCVWPRQ---CP----CLVDGARYWPGQRI---KADCQLCICQDG- 1895
Query: 692 VSCEPKACAPALCPFPARGDCCPDCD--------------GCEYLGESY-LSNQEFPDPR 736
P+ C DC DC G + + S+ SN P R
Sbjct: 1896 ---RPRRCR-------LNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGR 1945
Query: 737 ----------------EPCNLCTCLGGFVTCGRR----PCEPPGCSHPLIPSGHCCPTCQ 776
EPC C G G R PC C H L + HC P C
Sbjct: 1946 GRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNL--TAHCSPYCP 2003
Query: 777 --GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP-------- 826
C G L + +C C G + + PA P PSP
Sbjct: 2004 LGSC-------PQGWVLVEGTGESCCHCAL-PGENQTVQPMATPAAAPAPSPQIRFPLAT 2055
Query: 827 -------GPCFCPVCHSCLSQGREHQDGEEFEGP 853
PC+ P+ + L++G H ++ E P
Sbjct: 2056 YILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHP 2089
Score = 69.7 bits (169), Expect = 2e-11
Identities = 158/647 (24%), Positives = 201/647 (31%), Gaps = 172/647 (26%)
Query: 119 CQDGA----AHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCS 174
C DGA HC P LP + G + G+ +T S + P C
Sbjct: 1517 CPDGADEGPGHC-PLPSLPTPPASTLPGPSPGSLDTASSPLASAS---------PAPPCG 1566
Query: 175 --ELNCLES-CTPPGECCPI--CCTEGGSHWEHGQEWTTPGDPC-RICRCLEGHIQCRQR 228
E C CTP G C C +G G PC R C+ C
Sbjct: 1567 PFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQLC--- 1623
Query: 229 ECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
+ CP + P C G G P +G PC C NG+ L C
Sbjct: 1624 DGVRQCPDGSDEGPDAC----------GGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVC 1673
Query: 289 PPVP-CRHPGKIPGQCCPVCDGCEYQGHQY---QSQETFRLQERGLCVRCSCQAGEVSCE 344
P C PG++ P GC G T +G RCS V
Sbjct: 1674 DGQPDCGRPGQVGPS--PEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVL-- 1729
Query: 345 EQECPVTPCALPASGRQLC--PACELDGEEFAEGVQWEPDGRPCTACVC--------QDG 394
Q CP P Q C AC +DG E++ W PC + Q+G
Sbjct: 1730 -QNCPG-----PEHQSQACFTAACPVDG-EWSTWSPWSVCSEPCRGTMTRQRQCHSPQNG 1782
Query: 395 VPKCGAV-----------LCPPAPCQHPT-------QPPGACCPSCDSCTYHSQVYANGQ 436
C A+ CP C + T QP C +CD +GQ
Sbjct: 1783 GRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDD--------ISGQ 1834
Query: 437 NFTDADSPCHA--CHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDG 494
D PC + C C +G V S C P+ +CP C+++ + G
Sbjct: 1835 VTCPPDWPCGSPGCWCPEGQVLGS-----EGWCVWPR--------QCP-CLVDGARYWPG 1880
Query: 495 ESFSHPRDPCQECRCQEGH----------------------AHC---------------- 516
+ + CQ C CQ+G A C
Sbjct: 1881 QRI---KADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSS 1937
Query: 517 -QPRPCPRA-PC--AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNV 572
PRP R C H C C GC G+ + G + PCR+C+CL
Sbjct: 1938 NNPRPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERW--HGGPCRVCQCLHNLT 1995
Query: 573 QCLARRCVPLPCPEPVLL---PGECCPQC--------------PAPAGCPRPGAAHARHQ 615
+ C CP+ +L GE C C PA A P P
Sbjct: 1996 AHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPAAAPAPSPQIRFPLAT 2055
Query: 616 EYFSPPGDPCRRCLCLDG------SVSCQRL--PCPPAPCAHPRQGP 654
P GDPC L L G S Q+L P A P QGP
Sbjct: 2056 YILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQGP 2102
Score = 68.9 bits (167), Expect = 3e-11
Identities = 220/972 (22%), Positives = 298/972 (30%), Gaps = 242/972 (24%)
Query: 269 DPCSHCRCANGSV---QCEPLPCPPVPCRH----PGKIPG-----QCCPVCDGCEYQGHQ 316
DP S C C S +C P P R+ P PG +C P C G
Sbjct: 791 DPGSDCLCPVLSAYARRCAQEGASP-PWRNQTLCPVMCPGGQEYRECAPAC------GQH 843
Query: 317 YQSQETFRLQERGLCVR-CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAE 375
E E G CV C+C G + E +C +P S LCP C+L +A
Sbjct: 844 CGKPED--CGELGSCVAGCNCPLGLLWDPEGQC------VPPS---LCP-CQLGARRYAP 891
Query: 376 GVQWEPDGRPCTACVCQD-GVPKCGAVLCPP-APCQHP-TQPPGACCPSCDSCTYHSQVY 432
G + C C+CQ+ G+ C A CP A C PGAC +CDS + +
Sbjct: 892 G---SATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCP 948
Query: 433 ANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFV 492
A + C C GTV PP C SG P+ ++E+
Sbjct: 949 AGSTD---------GCVCPPGTVLLDERCVPPDLCPCRHSGQWY----LPNATIQED--- 992
Query: 493 DGESFSHPRDPCQECRCQEGHAHC----QPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKE 548
C C C+ HC + C + H + G AF
Sbjct: 993 -----------CNVCVCRGRQWHCTGQRRSGRCQASGAPHYV-------TFDGLAF---T 1031
Query: 549 YPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPG 608
YP ++ + L + N+ C A L C + + + E
Sbjct: 1032 YPGACEYLLVREASGLFTVSAQNLPCGAS---GLTCTKALAVRLEGTVVHMLRGRAVTVN 1088
Query: 609 AAHARHQEYFSPPGDPCRRC-------------LCLDGSVSCQRLPCPPAPCAHPRQGPC 655
+ ++ PG RR L DG R+ +P R
Sbjct: 1089 GVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGT---RVLVQLSPQFRGRVAGL 1145
Query: 656 CPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFP------AR 709
C DG G P+ A H W S C P C AR
Sbjct: 1146 CGDFDGDASNDLRSRQGVLEPTAELAAH---SWRLSPLCPEPGDLPHPCTMNTHRAGWAR 1202
Query: 710 GDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPG-----CSHP 764
C G L + E P P++ C + CG C+ G CS
Sbjct: 1203 ARC-----GALLQPLFTLCHAEVP-PQQHYEWCL----YDACG---CDSGGDCECLCSAI 1249
Query: 765 LIPSGHCCPTCQGCRYHGVTTAS----GETLPDPLDPTCSLCTCQEGSMRCQKKPCPPAL 820
+ C R+ S G + + PTC TC E
Sbjct: 1250 ATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCP-PTCHE-------------- 1294
Query: 821 CPHPSPG----------PCFCP---VCH--SCLSQGREHQDGEEFEGPAGS-----CEWC 860
HP PG CFCP + H +CL + P GS C C
Sbjct: 1295 -QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNC 1353
Query: 861 RCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHG------EEHPEGSRWVPPDS 914
CQ GQ C E + C C+ HG ++ +GS +
Sbjct: 1354 TCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGS----DEE 1409
Query: 915 ACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPC 974
C++ C EG +TC+ C+ C + DC G+ + PC
Sbjct: 1410 GCAAPGCGEGQMTCSSGHCLPLAL--------LCDRQDDC---------GDGTDEPSYPC 1452
Query: 975 EVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPG---PQHCCPTCAEALSNCSEGLL 1031
P+G L+ C + LPP H P C +A E L
Sbjct: 1453 --------PQG-------------LLACADGRCLPPALLCDGH--PDCLDAAD--EESCL 1487
Query: 1032 GSELAPPD--PCYTCQCQDLTWLCIH-QACPELS------CPLSERHTPPGSCCPVCRAP 1082
G P C C LC CP+ + CPL TPP S P P
Sbjct: 1488 GQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLP---GP 1544
Query: 1083 TQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGS---- 1138
+ + + AS + C RC S C+P D+ + GS
Sbjct: 1545 SPGSL----DTASSPLASASPAPPCGPF--EFRCGSGECTPRGWRCDQEEDCADGSDERG 1598
Query: 1139 CCPRCLPRPASC 1150
C C P A C
Sbjct: 1599 CGGPCAPHHAPC 1610
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/216 (26%), Positives = 79/216 (36%), Gaps = 52/216 (24%)
Query: 1309 NSWQVSEG--LW----PGRPCSAGREVDPCRAAGYRARREANARCGV----LKSSPFSRC 1358
+SW +EG W P CSA C + AR + V L ++P C
Sbjct: 3175 SSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLC 3234
Query: 1359 HAVVPPEPFFAACVYDLC-----------------ACGPGSSADACLCDAL--EAYASHC 1399
PE C+ C +CG G + CD + +C
Sbjct: 3235 SG---PEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC 3291
Query: 1400 RQAGVTPTWRGPTLCVVGCPLER-----GFVFDECGPPCPRTCFNQHIPLGELAAHCVRP 1454
P +G + CP+ G + CGPPCPR+C + HCV
Sbjct: 3292 EG----PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSC--------DDLVHCVWR 3339
Query: 1455 CVPGCQCPAG--LVEHEAHCIPPEACPQV-LLTGDQ 1487
C PGC CP G L + A C+ P C + LLTG +
Sbjct: 3340 CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQR 3375
Score = 52.4 bits (124), Expect = 3e-06
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 9/70 (12%)
Query: 1414 CVVGCPLERGF-VFDEC---GPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHE 1469
C CP F ++C G PCPR C Q + C C PGC CP GL H
Sbjct: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGI-----ECTGFCAPGCTCPPGLFLHN 2936
Query: 1470 AHCIPPEACP 1479
A C+P CP
Sbjct: 2937 ASCLPRSQCP 2946
Score = 50.8 bits (120), Expect = 1e-05
Identities = 44/163 (26%), Positives = 58/163 (35%), Gaps = 38/163 (23%)
Query: 68 MELREQNKDLQ---TRVRQLESCECHPASPQCWGLGRAWPEGARWEPDA----------- 113
+ L EQ ++L R C CH + C + P G W+ A
Sbjct: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC 4944
Query: 114 ----------------CTACVCQDG--AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDA 155
+ CVCQ G + GP HC C G+ + G + +A
Sbjct: 4945 LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCE-CWHLGRPHLPGSEWQ-EA 5002
Query: 156 CTTCRCLTGAVQCQGPSCSELNCL---ESCTPPGECCPICCTE 195
C +C CL+G C CS L C E PG CCP C E
Sbjct: 5003 CESCLCLSGRPVCT-QHCSPLTCAQGEEMVLEPGSCCPSCRRE 5044
Score = 49.7 bits (117), Expect = 2e-05
Identities = 51/173 (29%), Positives = 63/173 (36%), Gaps = 41/173 (23%)
Query: 1319 PGRPCSAGRE------VDPCRAAGYRARREANARCGVLKSSPF-SRCHAVVPPEPFFAAC 1371
PG C R V C AG A EA C V SR + V P P
Sbjct: 2533 PGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGG- 2591
Query: 1372 VYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVF-DECG 1430
A PG+S + C G+ P G C L R +V D C
Sbjct: 2592 -----APCPGASQERAPC-------------GLQPCSGG-----TDCELGRVYVSADLCQ 2628
Query: 1431 ----PPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACP 1479
PPCP +C + + C CV GC+CP GL+ H+ C+P CP
Sbjct: 2629 KGLVPPCPPSCLDP-----KANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECP 2676
Score = 46.6 bits (109), Expect = 2e-04
Identities = 85/351 (24%), Positives = 110/351 (31%), Gaps = 57/351 (16%)
Query: 72 EQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGA--AHCGPQ 129
E + TR RQ CH SPQ G A G C QDG A C +
Sbjct: 1764 EPCRGTMTRQRQ-----CH--SPQNGGRTCAALPGGLHSTRQTKPCP-QDGCPNATCSGE 1815
Query: 130 AHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECC 189
C C T PD C G+ C P L C P +C
Sbjct: 1816 LMFQPCAPCPLTCDDISGQVTCPPD--WPC----GSPGCWCPEGQVLGSEGWCVWPRQCP 1869
Query: 190 PICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQ-CRQR-ECASLCPYPARPLPGTCCP 247
C +G +W GQ C++C C +G + CR +CA C + + C
Sbjct: 1870 --CLVDGARYWP-GQRIKAD---CQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLG 1923
Query: 248 VCDGCFLNG--REHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCP 305
C + R + P G G C Q EP
Sbjct: 1924 PCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEP-------------------- 1963
Query: 306 VCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPC----ALPASGRQ 361
C+GCE+QG ++ E + G C C C + CP+ C L +
Sbjct: 1964 -CEGCEHQGQVHRVGERW---HGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGE 2019
Query: 362 LCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPA-PCQHP 411
C C L GE P P + Q P +L P PC P
Sbjct: 2020 SCCHCALPGENQTVQPMATPAAAPAPS--PQIRFPLATYILPPSGDPCYSP 2068
Score = 40.0 bits (92), Expect = 0.017
Identities = 44/169 (26%), Positives = 60/169 (35%), Gaps = 36/169 (21%)
Query: 655 CCPSCDGCLYQGKEFASGERFPSPTAAC---HLCLCWEGSVSCEPKACAPALCPF-PARG 710
C + G +G++ A F S AC H+ + W CE LCP
Sbjct: 423 CAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCE------RLCPGGQLYS 476
Query: 711 DCCPDCD-GCEYLGESYLSNQEFPDPREPC-NLCTCLGGFVTCGRRPCEPPGCSHPLIPS 768
DC C CE +G+ E RE C + C C G G +P+
Sbjct: 477 DCVSLCPPSCEAVGQG-----EEESCREECVSGCECPRGLFWNGTL----------CVPA 521
Query: 769 GHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCP 817
HC C CR V D + C+ C C++G C + CP
Sbjct: 522 AHC--PCYYCRQRYVPG-------DTVRQLCNPCVCRDGRWHCAQALCP 561
Score = 39.3 bits (90), Expect = 0.029
Identities = 57/203 (28%), Positives = 71/203 (34%), Gaps = 45/203 (22%)
Query: 218 CLEGHIQCRQRE---CASLCPYPARPLPGTCCPVCD-GCFLNGREHRSGEPVGSGDPC-S 272
C HI R R+ C LCP L C +C C G+ GE + C S
Sbjct: 450 CARRHIHIRWRKPGFCERLCP--GGQLYSDCVSLCPPSCEAVGQ----GEEESCREECVS 503
Query: 273 HCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCV 332
C C G L C VP H CP C Y +Y +T R LC
Sbjct: 504 GCECPRGLFWNGTL-C--VPAAH--------CP----CYYCRQRYVPGDTVRQ----LCN 544
Query: 333 RCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQ 392
C C+ G C + CP CA+ G L DG ++ W G+ C + Q
Sbjct: 545 PCVCRDGRWHCAQALCP-AECAVGGDGHYL----TFDGRSYS---FW--GGQGCRYSLVQ 594
Query: 393 DGVPKCGAVL-----CPPAPCQH 410
D V +L C C H
Sbjct: 595 DYVKGQLLILLEHGACDAGSCLH 617
Score = 37.4 bits (85), Expect = 0.11
Identities = 34/105 (32%), Positives = 43/105 (40%), Gaps = 23/105 (21%)
Query: 855 GSCEWCRCQAGQV--SCVRLQCPPLPCKLQVTERGSCCPRC-RGC--------------- 896
G CE C GQ+ CV L CPP + E SC C GC
Sbjct: 463 GFCERL-CPGGQLYSDCVSL-CPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVP 520
Query: 897 LAHGEEHPEGSRWVPPDSA---CSSCVCHEGVVTCARIQCISSCA 938
AH + R+VP D+ C+ CVC +G CA+ C + CA
Sbjct: 521 AAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECA 565
Score = 36.2 bits (82), Expect = 0.25
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 1417 GCP---LERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPC-VPGCQCPAG-LVEHEAH 1471
GCP +F C P CP TC + G++ PC PGC CP G ++ E
Sbjct: 1806 GCPNATCSGELMFQPCAP-CPLTCDDIS---GQVTCPPDWPCGSPGCWCPEGQVLGSEGW 1861
Query: 1472 CIPPEACP 1479
C+ P CP
Sbjct: 1862 CVWPRQCP 1869
Score = 35.0 bits (79), Expect = 0.55
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 11/62 (17%)
Query: 1429 CGPPCPRTC--FNQHIPLGELAAHCV---------RPCVPGCQCPAGLVEHEAHCIPPEA 1477
C P P C Q + + A C + C PGC CP+G++ C+P +
Sbjct: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD 3141
Query: 1478 CP 1479
CP
Sbjct: 3142 CP 3143
Score = 33.1 bits (74), Expect = 2.1
Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 21/119 (17%)
Query: 536 PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS-GNVQCLARRCVP-LPCPEPVLLPGE 593
P C GG+ Y PS C + G + CV CP + G
Sbjct: 462 PGFCERLCPGGQLYSDCVSLCPPS-----CEAVGQGEEESCREECVSGCECPRGLFWNGT 516
Query: 594 CCPQCPAPAGCPRPGAAHARHQEYFSPPGDP----CRRCLCLDGSVSCQRLPCPPAPCA 648
C PA A CP + Q Y PGD C C+C DG C + C PA CA
Sbjct: 517 LC--VPA-AHCP----CYYCRQRYV--PGDTVRQLCNPCVCRDGRWHCAQALC-PAECA 565
Score = 33.1 bits (74), Expect = 2.1
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 23/103 (22%)
Query: 362 LCP-ACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 420
LCP +CE G+ E + E + C C G+ G LC PA A CP
Sbjct: 481 LCPPSCEAVGQGEEESCREEC----VSGCECPRGLFWNGT-LCVPA----------AHCP 525
Query: 421 SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCP 463
C Y Q Y G C+ C C+DG C+ CP
Sbjct: 526 ----CYYCRQRYVPGDTVRQL---CNPCVCRDGRWHCAQALCP 561
Score = 32.3 bits (72), Expect = 3.5
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 29/102 (28%)
Query: 450 CQDGTVTCSLVD-CPPTTCARPQSGPGQC---------CPR--------------CPDCI 485
C G + V CPP+ A Q C CPR CP C
Sbjct: 469 CPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCP-CY 527
Query: 486 LEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
+ +V G++ R C C C++G HC CP A CA
Sbjct: 528 YCRQRYVPGDTV---RQLCNPCVCRDGRWHCAQALCP-AECA 565
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 254 bits (648), Expect = 6e-67
Identities = 159/446 (35%), Positives = 195/446 (43%), Gaps = 38/446 (8%)
Query: 399 GAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCS 458
G V+ P+ + P P A PS C + ++ + +T+ C C C+DG VTC
Sbjct: 362 GEVMGTPSSPRGPESPRLAAGPS--PCWHLGAMHESRSRWTEPG--CSQCWCEDGKVTCE 417
Query: 459 LVDCPPTTCARP-QSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQ 517
V C C+ P S G CCP C C V +G+ FS P + C C C G+ C
Sbjct: 418 KVRC-EAACSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLAGNVSCI 476
Query: 518 PRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLAR 577
CP PC P CC C F G+ Y GA F D C C C +G V+C
Sbjct: 477 SPECPSGPCQTPPQTDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFM 536
Query: 578 RCVPLPCP--EPVLLPGECCPQCPAP---AGCPRPGAAHARHQEYFSPPGDPCRRCLC-L 631
C L CP E L PG+CC C P GC PGDPC C+C
Sbjct: 537 PCPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGVEFPIGQIWSPGDPCELCICQA 596
Query: 632 DGSVSCQRLPCPPAPCAHPRQ--GPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCW 688
DGSVSC+R C + C HP + G CCP C GC Y G+ F + E FPS C C+C
Sbjct: 597 DGSVSCKRTDCVDS-CPHPIRIPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICL 655
Query: 689 EGSVSCEPKACAPALC--PFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLG 746
GSV+C P C P C PF G+CCP C C Y G + Q F EPC CTC
Sbjct: 656 LGSVACSPVDC-PITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQL 714
Query: 747 GFVTCGRRPCEPPGCSHPLIPSGHCCPTC----------QGCRYHGVTTASGETLPDPLD 796
G V+C + PC+ C+ P + G CC +C QG HG S
Sbjct: 715 GEVSCEKVPCQ-RACADPALLPGDCCSSCPDSLSPLEEKQGLSPHGNVAFS--------K 765
Query: 797 PTCSLCTCQEGSMRCQKKPCPPALCP 822
SL E + C P PP P
Sbjct: 766 AGRSLHGDTEAPVNCSSCPGPPTASP 791
Score = 232 bits (591), Expect = 2e-60
Identities = 149/412 (36%), Positives = 178/412 (43%), Gaps = 49/412 (11%)
Query: 378 QWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQP-PGACCPSCDSCTYHSQVYANGQ 436
+W G C+ C C+DG C V C A C HP G CCPSC C + V A G
Sbjct: 398 RWTEPG--CSQCWCEDGKVTCEKVRCEAA-CSHPIPSRDGGCCPSCTGCFHSGVVRAEGD 454
Query: 437 NFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP-DCILEEEVFVDGE 495
F+ + C C C G V+C +CP C P CC P C + DG
Sbjct: 455 VFSPPNENCTVCVCLAGNVSCISPECPSGPCQTPPQ--TDCCTCVPVRCYFHGRWYADGA 512
Query: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL----PGTCC-----PNDCSGCAF-- 544
FS D C C CQ G C PCP C PG CC P +GC+
Sbjct: 513 VFSGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDD 572
Query: 545 GGKEYPSGADFPHPSDPCRLCRC-LSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAG 603
G E+P G + P DPC LC C G+V C CV CP P+ +PG+CCP C AG
Sbjct: 573 NGVEFPIGQIW-SPGDPCELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDC--SAG 628
Query: 604 CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP--RQGPCCPSCDG 661
C G + E F DPC C+CL GSV+C + C P C +P G CCP C
Sbjct: 629 CTYTGRIF-YNNETFPSVLDPCLSCICLLGSVACSPVDC-PITCTYPFHPDGECCPVCRD 686
Query: 662 CLYQGKEFASGERFPSPTAACHLCLCWEGSVSCE----PKACA-PALCPFPARGDCCPDC 716
C Y+G++ A+G+ F C C C G VSCE +ACA PAL P GDCC C
Sbjct: 687 CNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQRACADPALLP----GDCCSSC 742
Query: 717 DGC-----EYLGESYLSNQEFP--------DPREPCNLCTCLGGFVTCGRRP 755
E G S N F D P N +C G RP
Sbjct: 743 PDSLSPLEEKQGLSPHGNVAFSKAGRSLHGDTEAPVNCSSCPGPPTASPSRP 794
Score = 230 bits (587), Expect = 7e-60
Identities = 135/368 (36%), Positives = 166/368 (45%), Gaps = 33/368 (8%)
Query: 190 PICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVC 249
P C G+ E WT PG C C C +G + C + C + C +P G CCP C
Sbjct: 383 PSPCWHLGAMHESRSRWTEPG--CSQCWCEDGKVTCEKVRCEAACSHPIPSRDGGCCPSC 440
Query: 250 DGCFLNGREHRSGEPVG-SGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCP-VC 307
GCF +G G+ + C+ C C G+V C CP PC+ P + CC V
Sbjct: 441 TGCFHSGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPECPSGPCQTPPQT--DCCTCVP 498
Query: 308 DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCP--- 364
C + G Y F C C CQ GEV C CP C P +L P
Sbjct: 499 VRCYFHGRWYADGAVFS-GGGDECTTCVCQNGEVECSFMPCPELAC--PREEWRLGPGQC 555
Query: 365 -----------ACELD--GEEFAEGVQWEPDGRPCTACVCQ-DGVPKCGAVLCPPAPCQH 410
C LD G EF G W P G PC C+CQ DG C C + C H
Sbjct: 556 CFTCQEPTPSTGCSLDDNGVEFPIGQIWSP-GDPCELCICQADGSVSCKRTDCVDS-CPH 613
Query: 411 PTQPPGACCPSCDS-CTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCAR 469
P + PG CCP C + CTY +++ N + F PC +C C G+V CS VDC P TC
Sbjct: 614 PIRIPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLGSVACSPVDC-PITCTY 672
Query: 470 PQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHP 529
P G+CCP C DC E +G+ F+ +PC C CQ G C+ PC RA CA P
Sbjct: 673 PFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQRA-CADP 731
Query: 530 --LPGTCC 535
LPG CC
Sbjct: 732 ALLPGDCC 739
Score = 228 bits (582), Expect = 3e-59
Identities = 139/397 (35%), Positives = 176/397 (44%), Gaps = 39/397 (9%)
Query: 587 PVLLPGECC--------PQCPAPAGCPRP----GAAHARHQEYFSPPGDPCRRCLCLDGS 634
P LL GE P+ P A P P GA H + P C +C C DG
Sbjct: 357 PSLLQGEVMGTPSSPRGPESPRLAAGPSPCWHLGAMHESRSRWTEPG---CSQCWCEDGK 413
Query: 635 VSCQRLPCPPAPCAHP---RQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS 691
V+C+++ C A C+HP R G CCPSC GC + G A G+ F P C +C+C G+
Sbjct: 414 VTCEKVRCEAA-CSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLAGN 472
Query: 692 VSCEPKACAPALCPFPARGDCCPDCD-GCEYLGESYLSNQEFPDPREPCNLCTCLGGFVT 750
VSC C C P + DCC C + G Y F + C C C G V
Sbjct: 473 VSCISPECPSGPCQTPPQTDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVE 532
Query: 751 CGRRPCEPPGCSHP--LIPSGHCCPTCQ------GCRY--HGVTTASGETLPDPLDPTCS 800
C PC C + G CC TCQ GC +GV G+ + P DP C
Sbjct: 533 CSFMPCPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGVEFPIGQ-IWSPGDP-CE 590
Query: 801 LCTCQ-EGSMRCQKKPCPPALCPHPS--PGPCFCPVCHS-CLSQGREHQDGEEFEGPAGS 856
LC CQ +GS+ C++ C + CPHP PG C CP C + C GR + E F
Sbjct: 591 LCICQADGSVSCKRTDCVDS-CPHPIRIPGQC-CPDCSAGCTYTGRIFYNNETFPSVLDP 648
Query: 857 CEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSAC 916
C C C G V+C + CP + C G CCP CR C G + G + D C
Sbjct: 649 CLSCICLLGSVACSPVDCP-ITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPC 707
Query: 917 SSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSD 953
+ C C G V+C ++ C +CA P P DCC C D
Sbjct: 708 TRCTCQLGEVSCEKVPCQRACADPALLPGDCCSSCPD 744
Score = 212 bits (540), Expect = 2e-54
Identities = 140/390 (35%), Positives = 169/390 (43%), Gaps = 51/390 (13%)
Query: 77 LQTRVRQLESCECHPASPQ-------CWGLGRAWPEGARWEPDACTACVCQDGAAHC--- 126
LQ V S P SP+ CW LG +RW C+ C C+DG C
Sbjct: 360 LQGEVMGTPSSPRGPESPRLAAGPSPCWHLGAMHESRSRWTEPGCSQCWCEDGKVTCEKV 419
Query: 127 ---GPQAH---------LPHCRGCSQNGQTYGNGETFSP--DACTTCRCLTGAVQCQGPS 172
+H P C GC +G G+ FSP + CT C CL G V C P
Sbjct: 420 RCEAACSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPE 479
Query: 173 CSELNCLESCTPPG-ECC---PICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQR 228
C C TPP +CC P+ C G + G ++ GD C C C G ++C
Sbjct: 480 CPSGPCQ---TPPQTDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFM 536
Query: 229 ECASL-CPYPARPL-PGTCCPVCD------GCFL--NGREHRSGEPVGSGDPCSHCRC-A 277
C L CP L PG CC C GC L NG E G+ GDPC C C A
Sbjct: 537 PCPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGVEFPIGQIWSPGDPCELCICQA 596
Query: 278 NGSVQCEPLPCPPVPCRHPGKIPGQCCPVCD-GCEYQGHQYQSQETFRLQERGLCVRCSC 336
+GSV C+ C C HP +IPGQCCP C GC Y G + + ETF C+ C C
Sbjct: 597 DGSVSCKRTDCVD-SCPHPIRIPGQCCPDCSAGCTYTGRIFYNNETFP-SVLDPCLSCIC 654
Query: 337 QAGEVSCEEQECPVTPCALPAS-GRQLCPACE---LDGEEFAEGVQWEPDGRPCTACVCQ 392
G V+C +CP+T C P + CP C +G + A G + D PCT C CQ
Sbjct: 655 LLGSVACSPVDCPIT-CTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQ 713
Query: 393 DGVPKCGAVLCPPAPCQHPTQPPGACCPSC 422
G C V C A C P PG CC SC
Sbjct: 714 LGEVSCEKVPCQRA-CADPALLPGDCCSSC 742
Score = 205 bits (522), Expect = 2e-52
Identities = 129/371 (34%), Positives = 178/371 (47%), Gaps = 52/371 (14%)
Query: 796 DPTCSLCTCQEGSMRCQKKPCPPALCPHPSP---GPCFCPVCHSCLSQGREHQDGEEFEG 852
+P CS C C++G + C+K C A C HP P G C CP C C G +G+ F
Sbjct: 401 EPGCSQCWCEDGKVTCEKVRCEAA-CSHPIPSRDGGC-CPSCTGCFHSGVVRAEGDVFSP 458
Query: 853 PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCR-GCLAHGEEHPEGSRWVP 911
P +C C C AG VSC+ +CP PC Q + CC C HG + +G+ +
Sbjct: 459 PNENCTVCVCLAGNVSCISPECPSGPC--QTPPQTDCCTCVPVRCYFHGRWYADGAVFSG 516
Query: 912 PDSACSSCVCHEGVVTCARIQCISSCAQPRQ----GPHDCCPQCSD--------CEHEGR 959
C++CVC G V C+ + C A PR+ GP CC C + + G
Sbjct: 517 GGDECTTCVCQNGEVECSFMPC-PELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGV 575
Query: 960 KYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCP-PSQLLPPGPQHCCPT 1018
++ G+ + PG DPCE+CIC Q +G S+ C R C CP P ++ P CCP
Sbjct: 576 EFPIGQIWSPG-DPCELCIC--QADG--SVSCKRTDCVD--SCPHPIRI----PGQCCPD 624
Query: 1019 CAEALSNCSEGLLGSELAPP--DPCYTCQCQDLTWLCIHQACPELSCPLSERHT--PPGS 1074
C+ + +E P DPC +C C L AC + CP++ + P G
Sbjct: 625 CSAGCTYTGRIFYNNETFPSVLDPCLSCIC-----LLGSVACSPVDCPITCTYPFHPDGE 679
Query: 1075 CCPVCRAPTQSCVHQGREVASGERWTVDT--CTSCSCMAGTVRCQSQRCSPLSCGPDKAP 1132
CCPVCR C ++GR+VA+G+ +T+D CT C+C G V C+ C +C P
Sbjct: 680 CCPVCR----DCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQ-RACAD---P 731
Query: 1133 ALSPGSCCPRC 1143
AL PG CC C
Sbjct: 732 ALLPGDCCSSC 742
Score = 202 bits (515), Expect = 2e-51
Identities = 216/787 (27%), Positives = 261/787 (33%), Gaps = 175/787 (22%)
Query: 352 PCALPASGRQLCPACELDGEEFAEGV--QWEPD--GRPCTACVCQDGVPKCGAVLC-PPA 406
P A R+L P L G F G W P G CT +C G CG+ +C P
Sbjct: 30 PGHFAAERRRLGPHVCLSG--FGSGCCPGWAPSMGGGHCTLPLCSFG---CGSGICIAPN 84
Query: 407 PCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTT 466
C GA CP H G + T C+ CQ+ C P
Sbjct: 85 VCSCQDGEQGATCPET-----HGPCGEYGCDLT-----CNHGGCQEVARVC------PVG 128
Query: 467 CARPQSGPGQCCPRCPDCILE---------EEVFV----DGESFSHPRDPCQE------- 506
+ ++ G C +C+ E FV G S R CQ+
Sbjct: 129 FSMTETAVGIRCTDIDECVTSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGT 188
Query: 507 --------------CRCQEG-HAHCQPRPCPRA-PCAHPLPGTCCPNDCSGCAFGGKEYP 550
C C+ G H H C C PL C + C
Sbjct: 189 PCQQRCKNSIGSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSC----------- 237
Query: 551 SGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGC----PR 606
H + LC C G + A R P+ VL P P+ P
Sbjct: 238 ------HNTVGSFLCTCRPG-FRLRADRVSCEAFPKAVLAPSAILQPRQHPSKMLLLLPE 290
Query: 607 PG--AAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP--------------------- 643
G A H PG P V RLP P
Sbjct: 291 AGRPALSPGHSPPSGAPGPPA--------GVRTTRLPSPTPRLPTSSPSAPVWLLSTLLA 342
Query: 644 -PAPCAH---------------------PRQGPCCPSCDG----CLYQGKEFASGERFPS 677
P P A PR GP P C + G S R+
Sbjct: 343 TPVPTASLLGNLRPPSLLQGEVMGTPSSPR-GPESPRLAAGPSPCWHLGAMHESRSRWTE 401
Query: 678 PTAACHLCLCWEGSVSCEPKACAPALC-PFPAR-GDCCPDCDGCEYLGESYLSNQEFPDP 735
P C C C +G V+CE C A P P+R G CCP C GC + G F P
Sbjct: 402 P--GCSQCWCEDGKVTCEKVRCEAACSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPP 459
Query: 736 REPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQG--CRYHGVTTASGETLPD 793
E C +C CL G V+C C C P P CC TC C +HG A G
Sbjct: 460 NENCTVCVCLAGNVSCISPECPSGPCQTP--PQTDCC-TCVPVRCYFHGRWYADGAVFSG 516
Query: 794 PLDPTCSLCTCQEGSMRCQKKPCPPALCPHPS----PGPCFCPVCHSCLSQGREHQD-GE 848
D C+ C CQ G + C PCP CP PG C S G D G
Sbjct: 517 GGDE-CTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGV 575
Query: 849 EFE-----GPAGSCEWCRCQA-GQVSCVRLQCPPLPCKLQVTERGSCCPRCR-GCLAHGE 901
EF P CE C CQA G VSC R C C + G CCP C GC G
Sbjct: 576 EFPIGQIWSPGDPCELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDCSAGCTYTGR 634
Query: 902 EHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKY 961
+ C SC+C G V C+ + C +C P +CCP C DC +EGRK
Sbjct: 635 IFYNNETFPSVLDPCLSCICLLGSVACSPVDCPITCTYPFHPDGECCPVCRDCNYEGRKV 694
Query: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAE 1021
G+ F +PC C C+ + C R C LL P CC +C +
Sbjct: 695 ANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQR-------ACADPALL---PGDCCSSCPD 744
Query: 1022 ALSNCSE 1028
+LS E
Sbjct: 745 SLSPLEE 751
Score = 108 bits (269), Expect = 5e-23
Identities = 71/216 (32%), Positives = 89/216 (41%), Gaps = 27/216 (12%)
Query: 100 GRAWPEGARWEP-DACTACVCQ-DGAAHCG--------------PQAHLPHCR-GCSQNG 142
G +P G W P D C C+CQ DG+ C P P C GC+ G
Sbjct: 574 GVEFPIGQIWSPGDPCELCICQADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAGCTYTG 633
Query: 143 QTYGNGETFSP--DACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPIC--CTEGGS 198
+ + N ETF D C +C CL G+V C C + C P GECCP+C C G
Sbjct: 634 RIFYNNETFPSVLDPCLSCICLLGSVACSPVDCP-ITCTYPFHPDGECCPVCRDCNYEGR 692
Query: 199 HWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGRE 258
+GQ +T +PC C C G + C + C C PA LPG CC C E
Sbjct: 693 KVANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQRACADPAL-LPGDCCSSCPDSLSPLEE 751
Query: 259 HRSGEPVGSGDPCSHCRCANGS----VQCEPLPCPP 290
+ P G+ R +G V C P PP
Sbjct: 752 KQGLSPHGNVAFSKAGRSLHGDTEAPVNCSSCPGPP 787
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 231 bits (589), Expect = 4e-60
Identities = 165/500 (33%), Positives = 226/500 (45%), Gaps = 71/500 (14%)
Query: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSN--CSEGLLGSELAPPDPCYTCQCQDLTWLC 1053
CP + CPP+ + C TC S CS+ + + C+C L
Sbjct: 1422 CP--MACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEA----------CECNPGFVLS 1469
Query: 1054 IHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQ-GREVASGERWTVDTCTS-CSCMA 1111
+ P C C+H G GERW C C C +
Sbjct: 1470 GLECIPRSQC---------------------GCLHPAGSYFKVGERWYKPGCKELCVCES 1508
Query: 1112 GT-VRCQSQRCSPLS-CGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQ 1169
+RCQ RC CG C + A+C A GDPHY TFDG L HF
Sbjct: 1509 NNRIRCQPWRCRAQEFCGQQDGIY----GCHAQ---GAATCTASGDPHYLTFDGALHHFM 1561
Query: 1170 GSCSYVLAKDCHSGD----FSVHVTNDDRGRS-GVAWTQEVAVLLGDMAVRLLQDGAVTV 1224
G+C+YVL + C S F V TN++RG V++ + V V + D+++ LL+ V +
Sbjct: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVML 1621
Query: 1225 DGHPVALP-FLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCG 1283
+GH VALP +L + + + L + V+L+ GLQV +DG VEV+VP SY G+ CGLCG
Sbjct: 1622 NGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCG 1681
Query: 1284 NFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREA 1343
N+N + DD P+ L G +W++ E PG G+ P
Sbjct: 1682 NYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK---PSSCQENSMADAW 1738
Query: 1344 NARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCR 1400
N C +L PFS+CH VVPP+ FA+CV+ C G+ D LC +L+AYAS C
Sbjct: 1739 NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC----GTKGDTTALCRSLQAYASLCA 1794
Query: 1401 QAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR--PCVPG 1458
QAG P WR T C + CP G + C PCP TC + + P C + PC
Sbjct: 1795 QAGQAPAWRNRTFCPMRCP--PGSSYSPCSSPCPDTCSSINNP-----RDCPKALPCAES 1847
Query: 1459 CQCPAGLVEHEAHCIPPEAC 1478
C+C G + C+P C
Sbjct: 1848 CECQKGHILSGTSCVPLGQC 1867
Score = 197 bits (502), Expect = 5e-50
Identities = 144/509 (28%), Positives = 210/509 (41%), Gaps = 63/509 (12%)
Query: 997 PSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQ 1056
P+ G + P P P + L + +E PP+ Y +
Sbjct: 1007 PTATGLAALVMSPHAPS--TPMTSVILGTTTTSRSSTERCPPNARY-------------E 1051
Query: 1057 ACPELSCPLSERHTPPGSCCPVCR------------------APTQSCVHQGREVASGER 1098
+C +CP S + +P SC P+CR A + +C + G
Sbjct: 1052 SC---ACPASCK-SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE 1107
Query: 1099 WTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDP 1156
W CT C C G+ V CQ +C G L G A+C+ +GDP
Sbjct: 1108 WFSPNCTEHCRCWPGSRVECQISQC-----GTHTVCQLKNGQYGCHPYAGTATCLVYGDP 1162
Query: 1157 HYRTFDGRLLHFQGSCSYVLAKDCHSGD---FSVHVTNDDRGRSGVAWTQEVAVLLGDMA 1213
HY TFDGR F G C+Y+LA+ C + F V N+++G+ GV+ +V V L +
Sbjct: 1163 HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPEST 1222
Query: 1214 VRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGS 1273
V LL+ V G V LP + +++ G V L + GL+V WDG Q+ V+V +
Sbjct: 1223 VTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
Query: 1274 YQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PC 1332
Y G+ CGLCGN++G + +D +G + GNSWQ + + C + V+ P
Sbjct: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD--EDQECQKYQVVNSPS 1340
Query: 1333 RAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCD 1390
+ ++ CG L + PF C V FF +C+ D+C LC
Sbjct: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF---QGLQHLLCT 1397
Query: 1391 ALEAYASHCRQAG-VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAA 1449
+ + C+ AG WR P C + CP + C PCP TC + G
Sbjct: 1398 HMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSL--CAKPCPDTCHS-----GFSGM 1450
Query: 1450 HCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
C CV C+C G V CIP C
Sbjct: 1451 FCSDRCVEACECNPGFVLSGLECIPRSQC 1479
Score = 159 bits (401), Expect = 3e-38
Identities = 167/624 (26%), Positives = 251/624 (40%), Gaps = 101/624 (16%)
Query: 900 GEEHPEGSRWVPPDSACSSCV--------CHEGVVTCARIQCISSCAQPRQGPHDCC--- 948
G+ G+ W P+S+ C C E + A + + P QGP C
Sbjct: 1700 GDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINP-QGPFSQCHQV 1758
Query: 949 --PQCS-------DCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSL 999
PQ S C +G S Q A C Q P+ R +R CP
Sbjct: 1759 VPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCA------QAGQAPAWR-NRTFCP-- 1809
Query: 1000 VGCPPSQLLPPGPQHCCPTCAEALS--NCSEGLLGSELAPPDPCY-TCQCQDLTWLCIHQ 1056
+ CPP P C TC+ + +C + L PC +C+CQ L
Sbjct: 1810 MRCPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTS 1860
Query: 1057 ACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERW-TVDTCTS-CSCMAGTV 1114
P C ++ P GS PV GERW T +TCT C+C
Sbjct: 1861 CVPLGQCGCTD---PAGSYHPV-----------------GERWYTENTCTRLCTCSVHN- 1899
Query: 1115 RCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CMAFGDPHYRTFDGRLLHFQGSCS 1173
+ C +C P++ G RC C G+ HY +FDG +C+
Sbjct: 1900 ---NITCFQSTCKPNQICWALDGLL--RCRASGVGVCQLPGESHYVSFDGSNHSIPDACT 1954
Query: 1174 YVLAKDCHSGD----FSVHVTND-DRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHP 1228
VL K CH F + ++ + G + EV + + D V L + V ++
Sbjct: 1955 LVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQ 2014
Query: 1229 VALPFLQE-PLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNG 1287
V LP + + P + V+ I++ + G+QV +DG +E+ +P +Y G+ CG+CGNFN
Sbjct: 2015 VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFND 2074
Query: 1288 FAQDDLQGPEGLLLPSEAAFGNSWQ-------VSEGLWPGRPCSAGREVDP---CRAAGY 1337
+D+L P + S++ F NSW+ L + A ++ +P CRAA
Sbjct: 2075 EEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADL 2134
Query: 1338 RARREANARC-GVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYA 1396
R RE +C L++ +++C + + PF C LC G A LC AL+A+
Sbjct: 2135 RRARE---KCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA---LCQALQAFG 2188
Query: 1397 SHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGEL-AAHCVRP 1454
+ C+ G+ P WR + C + CP + C P C +C++ G A
Sbjct: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYT--NCLPSCSPSCWDLD---GRCEGAKVPSA 2243
Query: 1455 CVPGCQCPAGLVEHEAHCIPPEAC 1478
C GC C G V E C+P C
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQC 2267
Score = 127 bits (318), Expect = 1e-28
Identities = 140/566 (24%), Positives = 190/566 (33%), Gaps = 106/566 (18%)
Query: 979 CEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPP 1038
C+ Q PP R + CP + CP C P+C + C + S A
Sbjct: 2191 CQSQGLKPPLWR-NSSFCP--LECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
Query: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
C CQ L + P C + H G + G+
Sbjct: 2248 -----CICQPGYVLSEDKCVPRSQCGCKDAH--------------------GGSIPLGKS 2282
Query: 1099 WTVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPH 1157
W CT C C G ++C RC P S +C + C +GDP
Sbjct: 2283 WVSSGCTEKCVCTGGAIQCGDFRC-PSGSHCQLTSDNSNSNCVS---DKSEQCSVYGDPR 2338
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHV------TNDDRGRSGVAWTQEVAVLLGD 1211
Y TFDG QG +YVL K V D RS + + QEV +
Sbjct: 2339 YLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI-FLQEVITTVYG 2397
Query: 1212 MAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVP 1271
V+L + V+ +A+P+ L V L G + L L V + G+ +S+P
Sbjct: 2398 YKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
Query: 1272 GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQV----------------SE 1315
Y+G GLCGN++ ++D+ P G L + FGNSW+V E
Sbjct: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
Query: 1316 GLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDL 1375
G G +V C + R PF+ CH V PEPF CV DL
Sbjct: 2518 GQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577
Query: 1376 CACGPGSSADACLCDALEAYASHCR---------------QAGVTPTWRG---------P 1411
C+ + C L + R Q G RG P
Sbjct: 2578 CSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHP 2637
Query: 1412 TLCV----------VGC-------PLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRP 1454
LC+ GC L F+ ++C C TC + I L E +
Sbjct: 2638 RLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRC--TCASSRILLCEPFS----- 2690
Query: 1455 CVPGCQCPAGLVEHEAHCIPPEACPQ 1480
C G C G H C P C Q
Sbjct: 2691 CRAGEVCTLG--NHTQGCFPESPCLQ 2714
Score = 42.7 bits (99), Expect = 0.003
Identities = 43/136 (31%), Positives = 51/136 (37%), Gaps = 29/136 (21%)
Query: 811 CQKKPCPPALCPHPSPGPCFCPVCHS---CL---SQGREHQDG--EEFEGPAGSCEWCRC 862
CQ + P L + S P CP S CL S DG E + P+ E C C
Sbjct: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
Query: 863 QAGQVSCVRLQCPPLPCKLQVTERGSCCPRCR-GCL-AHGEEHPEGSRWVPPDSACSS-C 919
Q G V C PR + GC AHG P G WV S C+ C
Sbjct: 2251 QPGYV----------------LSEDKCVPRSQCGCKDAHGGSIPLGKSWV--SSGCTEKC 2292
Query: 920 VCHEGVVTCARIQCIS 935
VC G + C +C S
Sbjct: 2293 VCTGGAIQCGDFRCPS 2308
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/136 (29%), Positives = 51/136 (37%), Gaps = 21/136 (15%)
Query: 642 CPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
CP A+ C PSC + G + PS A C+C G V E K C P
Sbjct: 2207 CPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS--ACAEGCICQPGYVLSEDK-CVP 2263
Query: 702 ALCPFPARGDC-CPDCDGCEY-LGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPP 759
R C C D G LG+S++S+ C C GG + CG C P
Sbjct: 2264 -------RSQCGCKDAHGGSIPLGKSWVSS-------GCTEKCVCTGGAIQCGDFRC--P 2307
Query: 760 GCSHPLIPSGHCCPTC 775
SH + S + C
Sbjct: 2308 SGSHCQLTSDNSNSNC 2323
Score = 41.2 bits (95), Expect = 0.008
Identities = 50/193 (25%), Positives = 61/193 (31%), Gaps = 33/193 (17%)
Query: 755 PCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGET--LPDPLDPTCSLCTCQEGSMRCQ 812
P P H ++P +C HG G+T L L SLC Q G
Sbjct: 1748 PQGPFSQCHQVVPPQSSFASC----VHGQCGTKGDTTALCRSLQAYASLCA-QAGQAPAW 1802
Query: 813 KKP--CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
+ CP P S PC P +C S + E C CQ G +
Sbjct: 1803 RNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALP----CAESCECQKGHI-LS 1857
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCL-AHGEEHPEGSRWVPPDSACSSCVCHEGVVTCA 929
C PL G C GC G HP G RW ++ C C
Sbjct: 1858 GTSCVPL---------GQC-----GCTDPAGSYHPVGERWYTENTCTRLCTCS----VHN 1899
Query: 930 RIQCISSCAQPRQ 942
I C S +P Q
Sbjct: 1900 NITCFQSTCKPNQ 1912
Score = 39.7 bits (91), Expect = 0.022
Identities = 37/137 (27%), Positives = 52/137 (37%), Gaps = 24/137 (17%)
Query: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCD-GCFLNGREHRSGEPVGS 267
PG P + L G ++ R C P P P+ D GC NG ++ G +
Sbjct: 2619 PGRPRGLRGPLRGRLRQHPRLCLQWHPEP---------PLADCGCTSNGIYYQLGSSFLT 2669
Query: 268 GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPV---CDGC--EYQGHQYQSQET 322
D C CA+ + L C P CR G+ C + GC E Q Q
Sbjct: 2670 EDCSQRCTCASSRI----LLCEPFSCR-----AGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Query: 323 FRLQERGLCVRCSCQAG 339
+ +E+G C C+ G
Sbjct: 2721 GQCREQGATFTCECEVG 2737
Score = 39.3 bits (90), Expect = 0.029
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 142 GQTYGNGETFSPDACTTC---RCLTGAVQC-QGPSCSELNCLE--SCTPPGECCPICCTE 195
G +Y + PD C++ R A+ C + C + + L SC P G+C C
Sbjct: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCG--CTDP 1872
Query: 196 GGSHWEHGQEWTTPGDPCRICRC-LEGHIQCRQREC 230
GS+ G+ W T R+C C + +I C Q C
Sbjct: 1873 AGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 37.0 bits (84), Expect = 0.14
Identities = 59/263 (22%), Positives = 87/263 (33%), Gaps = 49/263 (18%)
Query: 657 PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCP-- 714
PSC L ++ + E+ +P+ C CE AP +R D P
Sbjct: 2105 PSCQSLLVDEQQIPA-EQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFL 2163
Query: 715 -DCDG--CEYLGESYLSNQEFPDPREPCNLCTCLGGF-VTCGRRPCEPPGCSH------- 763
DC CE+ G Y + LC L F TC + +PP +
Sbjct: 2164 VDCANTLCEF-GGLYQA------------LCQALQAFGATCQSQGLKPPLWRNSSFCPLE 2210
Query: 764 -PLIPS-GHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821
P S +C P+C + G +P C CQ G + + K P + C
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC---AEGCICQPGYVLSEDKCVPRSQC 2267
Query: 822 PHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPP-LPCK 880
P+ S +S +G E C C G + C +CP C+
Sbjct: 2268 GCKDAHGGSIPLGKSWVS--------------SGCTEKCVCTGGAIQCGDFRCPSGSHCQ 2313
Query: 881 LQVTERGSCC--PRCRGCLAHGE 901
L S C + C +G+
Sbjct: 2314 LTSDNSNSNCVSDKSEQCSVYGD 2336
Score = 37.0 bits (84), Expect = 0.14
Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 17/103 (16%)
Query: 128 PQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAV------QCQ-GPSCSELNCL 179
P+ L C GC+ NG Y G +F + C+ C C + + C+ G C+ N
Sbjct: 2645 PEPPLADC-GCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHT 2703
Query: 180 ESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGH 222
+ C P C C G E G +T C C G+
Sbjct: 2704 QGCFPESPCLQNPCQNDGQCREQGATFT--------CECEVGY 2738
Score = 35.4 bits (80), Expect = 0.42
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 14/90 (15%)
Query: 334 CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA-CVCQ 392
C CQ G V E++ P R C + G G W G CT CVC
Sbjct: 2248 CICQPGYVLSEDKCVP----------RSQCGCKDAHGGSIPLGKSWVSSG--CTEKCVCT 2295
Query: 393 DGVPKCGAVLCPP-APCQHPTQPPGACCPS 421
G +CG CP + CQ + + C S
Sbjct: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVS 2325
Score = 35.0 bits (79), Expect = 0.55
Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 20/89 (22%)
Query: 104 PEGARWEPDACTACVCQDGAAHCGPQAHLP------------HCR-----GCSQNGQTYG 146
P AR+E AC A C+ CGP HC C N Y
Sbjct: 1045 PPNARYESCACPAS-CKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
Query: 147 NG-ETFSPDACTTCRCLTGA-VQCQGPSC 173
G E FSP+ CRC G+ V+CQ C
Sbjct: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
Score = 32.7 bits (73), Expect = 2.7
Identities = 32/136 (23%), Positives = 45/136 (33%), Gaps = 43/136 (31%)
Query: 518 PRPCPR----APCAHPLPGTCC----PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS 569
P CP +PC+ P P TC P DC P C C
Sbjct: 1809 PMRCPPGSSYSPCSSPCPDTCSSINNPRDC----------------PKALPCAESCECQK 1852
Query: 570 GNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCL 629
G++ CVPL G+C GC P ++ E + R C
Sbjct: 1853 GHI-LSGTSCVPL---------GQC--------GCTDPAGSYHPVGERWYTENTCTRLCT 1894
Query: 630 C-LDGSVSCQRLPCPP 644
C + +++C + C P
Sbjct: 1895 CSVHNNITCFQSTCKP 1910
Score = 32.0 bits (71), Expect = 4.6
Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 17/108 (15%)
Query: 126 CGPQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAVQCQGPSCSELNCLESCTP 184
C P + C + G F D C C C G V L+ LE C P
Sbjct: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV---------LSGLE-CIP 1475
Query: 185 PGECCPICCTEGGSHWEHGQEWTTPGDPCR-ICRC-LEGHIQCRQREC 230
+C C GS+++ G+ W PG C+ +C C I+C+ C
Sbjct: 1476 RSQCG--CLHPAGSYFKVGERWYKPG--CKELCVCESNNRIRCQPWRC 1519
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 231 bits (589), Expect = 4e-60
Identities = 165/500 (33%), Positives = 226/500 (45%), Gaps = 71/500 (14%)
Query: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSN--CSEGLLGSELAPPDPCYTCQCQDLTWLC 1053
CP + CPP+ + C TC S CS+ + + C+C L
Sbjct: 1422 CP--MACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEA----------CECNPGFVLS 1469
Query: 1054 IHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQ-GREVASGERWTVDTCTS-CSCMA 1111
+ P C C+H G GERW C C C +
Sbjct: 1470 GLECIPRSQC---------------------GCLHPAGSYFKVGERWYKPGCKELCVCES 1508
Query: 1112 GT-VRCQSQRCSPLS-CGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQ 1169
+RCQ RC CG C + A+C A GDPHY TFDG L HF
Sbjct: 1509 NNRIRCQPWRCRAQEFCGQQDGIY----GCHAQ---GAATCTASGDPHYLTFDGALHHFM 1561
Query: 1170 GSCSYVLAKDCHSGD----FSVHVTNDDRGRS-GVAWTQEVAVLLGDMAVRLLQDGAVTV 1224
G+C+YVL + C S F V TN++RG V++ + V V + D+++ LL+ V +
Sbjct: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVML 1621
Query: 1225 DGHPVALP-FLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCG 1283
+GH VALP +L + + + L + V+L+ GLQV +DG VEV+VP SY G+ CGLCG
Sbjct: 1622 NGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCG 1681
Query: 1284 NFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREA 1343
N+N + DD P+ L G +W++ E PG G+ P
Sbjct: 1682 NYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK---PSSCQENSMADAW 1738
Query: 1344 NARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCR 1400
N C +L PFS+CH VVPP+ FA+CV+ C G+ D LC +L+AYAS C
Sbjct: 1739 NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC----GTKGDTTALCRSLQAYASLCA 1794
Query: 1401 QAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR--PCVPG 1458
QAG P WR T C + CP G + C PCP TC + + P C + PC
Sbjct: 1795 QAGQAPAWRNRTFCPMRCP--PGSSYSPCSSPCPDTCSSINNP-----RDCPKALPCAES 1847
Query: 1459 CQCPAGLVEHEAHCIPPEAC 1478
C+C G + C+P C
Sbjct: 1848 CECQKGHILSGTSCVPLGQC 1867
Score = 197 bits (502), Expect = 5e-50
Identities = 144/509 (28%), Positives = 210/509 (41%), Gaps = 63/509 (12%)
Query: 997 PSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQ 1056
P+ G + P P P + L + +E PP+ Y +
Sbjct: 1007 PTATGLAALVMSPHAPS--TPMTSVILGTTTTSRSSTERCPPNARY-------------E 1051
Query: 1057 ACPELSCPLSERHTPPGSCCPVCR------------------APTQSCVHQGREVASGER 1098
+C +CP S + +P SC P+CR A + +C + G
Sbjct: 1052 SC---ACPASCK-SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE 1107
Query: 1099 WTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDP 1156
W CT C C G+ V CQ +C G L G A+C+ +GDP
Sbjct: 1108 WFSPNCTEHCRCWPGSRVECQISQC-----GTHTVCQLKNGQYGCHPYAGTATCLVYGDP 1162
Query: 1157 HYRTFDGRLLHFQGSCSYVLAKDCHSGD---FSVHVTNDDRGRSGVAWTQEVAVLLGDMA 1213
HY TFDGR F G C+Y+LA+ C + F V N+++G+ GV+ +V V L +
Sbjct: 1163 HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPEST 1222
Query: 1214 VRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGS 1273
V LL+ V G V LP + +++ G V L + GL+V WDG Q+ V+V +
Sbjct: 1223 VTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
Query: 1274 YQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PC 1332
Y G+ CGLCGN++G + +D +G + GNSWQ + + C + V+ P
Sbjct: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD--EDQECQKYQVVNSPS 1340
Query: 1333 RAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCD 1390
+ ++ CG L + PF C V FF +C+ D+C LC
Sbjct: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF---QGLQHLLCT 1397
Query: 1391 ALEAYASHCRQAG-VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAA 1449
+ + C+ AG WR P C + CP + C PCP TC + G
Sbjct: 1398 HMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSL--CAKPCPDTCHS-----GFSGM 1450
Query: 1450 HCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
C CV C+C G V CIP C
Sbjct: 1451 FCSDRCVEACECNPGFVLSGLECIPRSQC 1479
Score = 159 bits (401), Expect = 3e-38
Identities = 167/624 (26%), Positives = 251/624 (40%), Gaps = 101/624 (16%)
Query: 900 GEEHPEGSRWVPPDSACSSCV--------CHEGVVTCARIQCISSCAQPRQGPHDCC--- 948
G+ G+ W P+S+ C C E + A + + P QGP C
Sbjct: 1700 GDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINP-QGPFSQCHQV 1758
Query: 949 --PQCS-------DCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSL 999
PQ S C +G S Q A C Q P+ R +R CP
Sbjct: 1759 VPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCA------QAGQAPAWR-NRTFCP-- 1809
Query: 1000 VGCPPSQLLPPGPQHCCPTCAEALS--NCSEGLLGSELAPPDPCY-TCQCQDLTWLCIHQ 1056
+ CPP P C TC+ + +C + L PC +C+CQ L
Sbjct: 1810 MRCPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTS 1860
Query: 1057 ACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERW-TVDTCTS-CSCMAGTV 1114
P C ++ P GS PV GERW T +TCT C+C
Sbjct: 1861 CVPLGQCGCTD---PAGSYHPV-----------------GERWYTENTCTRLCTCSVHN- 1899
Query: 1115 RCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CMAFGDPHYRTFDGRLLHFQGSCS 1173
+ C +C P++ G RC C G+ HY +FDG +C+
Sbjct: 1900 ---NITCFQSTCKPNQICWALDGLL--RCRASGVGVCQLPGESHYVSFDGSNHSIPDACT 1954
Query: 1174 YVLAKDCHSGD----FSVHVTND-DRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHP 1228
VL K CH F + ++ + G + EV + + D V L + V ++
Sbjct: 1955 LVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQ 2014
Query: 1229 VALPFLQE-PLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNG 1287
V LP + + P + V+ I++ + G+QV +DG +E+ +P +Y G+ CG+CGNFN
Sbjct: 2015 VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFND 2074
Query: 1288 FAQDDLQGPEGLLLPSEAAFGNSWQ-------VSEGLWPGRPCSAGREVDP---CRAAGY 1337
+D+L P + S++ F NSW+ L + A ++ +P CRAA
Sbjct: 2075 EEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADL 2134
Query: 1338 RARREANARC-GVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYA 1396
R RE +C L++ +++C + + PF C LC G A LC AL+A+
Sbjct: 2135 RRARE---KCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA---LCQALQAFG 2188
Query: 1397 SHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGEL-AAHCVRP 1454
+ C+ G+ P WR + C + CP + C P C +C++ G A
Sbjct: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYT--NCLPSCSPSCWDLD---GRCEGAKVPSA 2243
Query: 1455 CVPGCQCPAGLVEHEAHCIPPEAC 1478
C GC C G V E C+P C
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQC 2267
Score = 142 bits (357), Expect = 3e-33
Identities = 123/464 (26%), Positives = 168/464 (36%), Gaps = 57/464 (12%)
Query: 979 CEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPP 1038
C+ Q PP R + CP + CP C P+C + C + S A
Sbjct: 2191 CQSQGLKPPLWR-NSSFCP--LECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
Query: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
C CQ L + P C + H G + G+
Sbjct: 2248 -----CICQPGYVLSEDKCVPRSQCGCKDAH--------------------GGSIPLGKS 2282
Query: 1099 WTVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPH 1157
W CT C C G ++C RC P S +C + C +GDP
Sbjct: 2283 WVSSGCTEKCVCTGGAIQCGDFRC-PSGSHCQLTSDNSNSNCVS---DKSEQCSVYGDPR 2338
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHV------TNDDRGRSGVAWTQEVAVLLGD 1211
Y TFDG QG +YVL K V D RS + + QEV +
Sbjct: 2339 YLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI-FLQEVITTVYG 2397
Query: 1212 MAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVP 1271
V+L + V+ +A+P+ L V L G + L L V + G+ +S+P
Sbjct: 2398 YKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
Query: 1272 GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQV----------------SE 1315
Y+G GLCGN++ ++D+ P G L + FGNSW+V E
Sbjct: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
Query: 1316 GLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDL 1375
G G +V C + R PF+ CH V PEPF CV DL
Sbjct: 2518 GQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577
Query: 1376 CACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCVVGC 1418
C+ + C L YA C++AG WR TLC C
Sbjct: 2578 CSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 42.7 bits (99), Expect = 0.003
Identities = 43/136 (31%), Positives = 51/136 (37%), Gaps = 29/136 (21%)
Query: 811 CQKKPCPPALCPHPSPGPCFCPVCHS---CL---SQGREHQDG--EEFEGPAGSCEWCRC 862
CQ + P L + S P CP S CL S DG E + P+ E C C
Sbjct: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
Query: 863 QAGQVSCVRLQCPPLPCKLQVTERGSCCPRCR-GCL-AHGEEHPEGSRWVPPDSACSS-C 919
Q G V C PR + GC AHG P G WV S C+ C
Sbjct: 2251 QPGYV----------------LSEDKCVPRSQCGCKDAHGGSIPLGKSWV--SSGCTEKC 2292
Query: 920 VCHEGVVTCARIQCIS 935
VC G + C +C S
Sbjct: 2293 VCTGGAIQCGDFRCPS 2308
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/136 (29%), Positives = 51/136 (37%), Gaps = 21/136 (15%)
Query: 642 CPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
CP A+ C PSC + G + PS A C+C G V E K C P
Sbjct: 2207 CPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS--ACAEGCICQPGYVLSEDK-CVP 2263
Query: 702 ALCPFPARGDC-CPDCDGCEY-LGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPP 759
R C C D G LG+S++S+ C C GG + CG C P
Sbjct: 2264 -------RSQCGCKDAHGGSIPLGKSWVSS-------GCTEKCVCTGGAIQCGDFRC--P 2307
Query: 760 GCSHPLIPSGHCCPTC 775
SH + S + C
Sbjct: 2308 SGSHCQLTSDNSNSNC 2323
Score = 41.2 bits (95), Expect = 0.008
Identities = 50/193 (25%), Positives = 61/193 (31%), Gaps = 33/193 (17%)
Query: 755 PCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGET--LPDPLDPTCSLCTCQEGSMRCQ 812
P P H ++P +C HG G+T L L SLC Q G
Sbjct: 1748 PQGPFSQCHQVVPPQSSFASC----VHGQCGTKGDTTALCRSLQAYASLCA-QAGQAPAW 1802
Query: 813 KKP--CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
+ CP P S PC P +C S + E C CQ G +
Sbjct: 1803 RNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALP----CAESCECQKGHI-LS 1857
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCL-AHGEEHPEGSRWVPPDSACSSCVCHEGVVTCA 929
C PL G C GC G HP G RW ++ C C
Sbjct: 1858 GTSCVPL---------GQC-----GCTDPAGSYHPVGERWYTENTCTRLCTCS----VHN 1899
Query: 930 RIQCISSCAQPRQ 942
I C S +P Q
Sbjct: 1900 NITCFQSTCKPNQ 1912
Score = 39.3 bits (90), Expect = 0.029
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 142 GQTYGNGETFSPDACTTC---RCLTGAVQC-QGPSCSELNCLE--SCTPPGECCPICCTE 195
G +Y + PD C++ R A+ C + C + + L SC P G+C C
Sbjct: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCG--CTDP 1872
Query: 196 GGSHWEHGQEWTTPGDPCRICRC-LEGHIQCRQREC 230
GS+ G+ W T R+C C + +I C Q C
Sbjct: 1873 AGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 37.0 bits (84), Expect = 0.14
Identities = 59/263 (22%), Positives = 87/263 (33%), Gaps = 49/263 (18%)
Query: 657 PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCP-- 714
PSC L ++ + E+ +P+ C CE AP +R D P
Sbjct: 2105 PSCQSLLVDEQQIPA-EQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFL 2163
Query: 715 -DCDG--CEYLGESYLSNQEFPDPREPCNLCTCLGGF-VTCGRRPCEPPGCSH------- 763
DC CE+ G Y + LC L F TC + +PP +
Sbjct: 2164 VDCANTLCEF-GGLYQA------------LCQALQAFGATCQSQGLKPPLWRNSSFCPLE 2210
Query: 764 -PLIPS-GHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821
P S +C P+C + G +P C CQ G + + K P + C
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC---AEGCICQPGYVLSEDKCVPRSQC 2267
Query: 822 PHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPP-LPCK 880
P+ S +S +G E C C G + C +CP C+
Sbjct: 2268 GCKDAHGGSIPLGKSWVS--------------SGCTEKCVCTGGAIQCGDFRCPSGSHCQ 2313
Query: 881 LQVTERGSCC--PRCRGCLAHGE 901
L S C + C +G+
Sbjct: 2314 LTSDNSNSNCVSDKSEQCSVYGD 2336
Score = 35.4 bits (80), Expect = 0.42
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 14/90 (15%)
Query: 334 CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA-CVCQ 392
C CQ G V E++ P R C + G G W G CT CVC
Sbjct: 2248 CICQPGYVLSEDKCVP----------RSQCGCKDAHGGSIPLGKSWVSSG--CTEKCVCT 2295
Query: 393 DGVPKCGAVLCPP-APCQHPTQPPGACCPS 421
G +CG CP + CQ + + C S
Sbjct: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVS 2325
Score = 35.0 bits (79), Expect = 0.55
Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 20/89 (22%)
Query: 104 PEGARWEPDACTACVCQDGAAHCGPQAHLP------------HCR-----GCSQNGQTYG 146
P AR+E AC A C+ CGP HC C N Y
Sbjct: 1045 PPNARYESCACPAS-CKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
Query: 147 NG-ETFSPDACTTCRCLTGA-VQCQGPSC 173
G E FSP+ CRC G+ V+CQ C
Sbjct: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
Score = 32.7 bits (73), Expect = 2.7
Identities = 32/136 (23%), Positives = 45/136 (33%), Gaps = 43/136 (31%)
Query: 518 PRPCPR----APCAHPLPGTCC----PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS 569
P CP +PC+ P P TC P DC P C C
Sbjct: 1809 PMRCPPGSSYSPCSSPCPDTCSSINNPRDC----------------PKALPCAESCECQK 1852
Query: 570 GNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCL 629
G++ CVPL G+C GC P ++ E + R C
Sbjct: 1853 GHI-LSGTSCVPL---------GQC--------GCTDPAGSYHPVGERWYTENTCTRLCT 1894
Query: 630 C-LDGSVSCQRLPCPP 644
C + +++C + C P
Sbjct: 1895 CSVHNNITCFQSTCKP 1910
Score = 32.0 bits (71), Expect = 4.6
Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 17/108 (15%)
Query: 126 CGPQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAVQCQGPSCSELNCLESCTP 184
C P + C + G F D C C C G V L+ LE C P
Sbjct: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV---------LSGLE-CIP 1475
Query: 185 PGECCPICCTEGGSHWEHGQEWTTPGDPCR-ICRC-LEGHIQCRQREC 230
+C C GS+++ G+ W PG C+ +C C I+C+ C
Sbjct: 1476 RSQCG--CLHPAGSYFKVGERWYKPG--CKELCVCESNNRIRCQPWRC 1519
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 226 bits (575), Expect = 2e-58
Identities = 146/449 (32%), Positives = 196/449 (43%), Gaps = 56/449 (12%)
Query: 1040 PCY-TCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
PC TCQ + +C + SCP + G C P CVH G+ G
Sbjct: 307 PCARTCQSLHINEMCQERCVDGCSCPEGQL-LDEGLCVESTECP---CVHSGKRYPPGTS 362
Query: 1099 WTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHY 1158
+ D C +C C C ++ C P C+ G H+
Sbjct: 363 LSRD-CNTCICRNSQWICSNEEC-------------------------PGECLVTGQSHF 396
Query: 1159 RTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTN----DDRGRSGVAWTQEVAVLLGDM-- 1212
++FD R F G C Y+LA+DC FS+ + DDR T+ V V L +
Sbjct: 397 KSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRD---AVCTRSVTVRLPGLHN 453
Query: 1213 -AVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVP 1271
V+L V +DG V LP L+ L +V L LQ+ WDG+ ++ V +
Sbjct: 454 SLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLS 513
Query: 1272 GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDP 1331
Y G+TCGLCGN+NG DD P GL P FGN+W++ + + DP
Sbjct: 514 PVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDP 569
Query: 1332 CRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDA 1391
C A R R + C VL S F CH V P P+ C YD+C+C G CLC A
Sbjct: 570 C-ALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRE---CLCGA 625
Query: 1392 LEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
L +YA+ C GV WR P C + CP +G V+ +CG PC TC + P E C
Sbjct: 626 LASYAAACAGRGVRVAWREPGRCELNCP--KGQVYLQCGTPCNLTCRSLSYPDEE----C 679
Query: 1452 VRPCVPGCQCPAGL-VEHEAHCIPPEACP 1479
C+ GC CP GL ++ C+P CP
Sbjct: 680 NEACLEGCFCPPGLYMDERGDCVPKAQCP 708
Score = 195 bits (496), Expect = 2e-49
Identities = 204/711 (28%), Positives = 265/711 (37%), Gaps = 143/711 (20%)
Query: 816 CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCP 875
C A+ P P C VC SC S GRE C G ++ C
Sbjct: 595 CHRAVSPLPYLRNCRYDVC-SC-SDGRE------------------CLCGALASYAAACA 634
Query: 876 PLPCKLQVTERGSC---CPRCRGCLAHGEEHPEGSRWVP-PDSACSS-----CVCHEGVV 926
++ E G C CP+ + L G R + PD C+ C C G+
Sbjct: 635 GRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
Query: 927 TCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQ---- 982
R C+ P CP C ++G ++P + F +D +C CE
Sbjct: 695 MDERGDCV---------PKAQCP----CYYDGEIFQPEDIF---SDHHTMCYCEDGFMHC 738
Query: 983 ----------PEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLG 1032
P+ S R SL PP L CP A+ L +EGL
Sbjct: 739 TMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKL------VCP--ADNLR--AEGLEC 788
Query: 1033 SELAPPDPCYTCQCQDLTWLCIHQACPE--LSCPLSERHTPPGSCCPVCRAPTQSCVHQG 1090
++ TCQ DL C+ C L P RH C + R P C HQG
Sbjct: 789 TK--------TCQNYDLE--CMSMGCVSGCLCPPGMVRHE--NRCVALERCP---CFHQG 833
Query: 1091 REVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASC 1150
+E A GE + C +C C C C A+C
Sbjct: 834 KEYAPGETVKIG-CNTCVCRDRKWNCTDHVCD-------------------------ATC 867
Query: 1151 MAFGDPHYRTFDGRLLHFQGSCSYVLAKD-CHS--GDFSVHVTNDDRGRSGVAWTQEVAV 1207
G HY TFDG F G C YVL +D C S G F + V N V + V +
Sbjct: 868 STIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTI 927
Query: 1208 LLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVE 1267
L+ + L DG V V P E V G +IL L V+WD +
Sbjct: 928 LVEGGEIELF-DGEVNVKR-----PMKDETHFEVVESGRYIILLLGKALSVVWDRHLSIS 981
Query: 1268 VSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGR 1327
V + +YQ + CGLCGNF+G +DL + FGNSW+VS R
Sbjct: 982 VVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDS 1041
Query: 1328 EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADAC 1387
C + ++ C +L S F C+ +V PEP+ C+YD C+C AC
Sbjct: 1042 SPATCH-NNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDC-AC 1099
Query: 1388 LCDALEAYASHCRQAGVTPTWRGPTLCVVGCP----LERGFV----FDECGPPCPRTCFN 1439
CD + AYA C Q G TWR TLC C E G+ ++ C P C TC
Sbjct: 1100 FCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTC-- 1157
Query: 1440 QH-IPLGELAAHCVRPCVPGC--QCPAGLVEHE--AHCIPPEACPQVLLTG 1485
QH PL C CV GC CP G + E C+ PE CP + G
Sbjct: 1158 QHPEPLA-----CPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Score = 179 bits (454), Expect = 2e-44
Identities = 123/353 (34%), Positives = 159/353 (45%), Gaps = 26/353 (7%)
Query: 1136 PGSCCP---RCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTND 1192
PG+ C R A C FG TFDG + F G CSY+LA C FS+ D
Sbjct: 18 PGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI--IGD 75
Query: 1193 DRGRSGVAWTQEVAVLLGDMA-VRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILH 1251
+ V+ ++V LG+ + L +G VT V++P+ + L G+ +
Sbjct: 76 FQNGKRVS----LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSG 131
Query: 1252 AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSW 1311
G DG +V + Y +TCGLCGNFN FA+DD EG L F NSW
Sbjct: 132 EAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSW 191
Query: 1312 QVSEG-LWPGRPCSAGREVDPCRAAGYRARREANARCGVLKS-SPFSRCHAVVPPEPFFA 1369
+S G W R A C + ++ +C +LKS S F+RCH +V PEPF A
Sbjct: 192 ALSSGEQWCER---ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVA 248
Query: 1370 ACVYDLCACGPGSSADACLCDALEAYASHCRQAG-VTPTWRGPTLCVVGCPLERGFVFDE 1428
C LC C G C C AL YA C Q G V W + C CP G + +
Sbjct: 249 LCEKTLCECAGGLE---CACPALLEYARTCAQEGMVLYGWTDHSACSPVCP--AGMEYRQ 303
Query: 1429 CGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQV 1481
C PC RTC + HI E+ C CV GC CP G + E C+ CP V
Sbjct: 304 CVSPCARTCQSLHI--NEM---CQERCVDGCSCPEGQLLDEGLCVESTECPCV 351
Score = 122 bits (305), Expect = 3e-27
Identities = 114/423 (26%), Positives = 174/423 (41%), Gaps = 53/423 (12%)
Query: 1078 VCRAPTQSCVHQ-GREVASGERWTV-DTCTSCSCMA-GTVRCQSQRCS-----PLSCGPD 1129
+C + C+ + G E G+ WT+ D C + +C G +S R + SC
Sbjct: 1871 LCSGFVRICMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNS 1930
Query: 1130 KAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHV 1189
++P +C R P C H TFDG+ GSCSYVL ++ D V +
Sbjct: 1931 QSPVKVEETCGCRWTC-PCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQ-DLEVIL 1988
Query: 1190 TN---DDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGH 1246
N R G + + V ++V L D VTV+G V++P++ + E+ +
Sbjct: 1989 HNGACSPGARQGCM--KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNM---EVNVY 2043
Query: 1247 TVILHA----QPGLQVLWDGQS---QVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGL 1299
I+H G + Q+ Q+++S P ++ +T GLCG + +D +G
Sbjct: 2044 GAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKTFASKTYGLCGICDENGANDFMLRDGT 2102
Query: 1300 LLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCH 1359
+ W V PG+ C E + C ++ C VL F+ CH
Sbjct: 2103 VTTDWKTLVQEWTVQR---PGQTCQPILE-EQCLVPD-------SSHCQVLLLPLFAECH 2151
Query: 1360 AVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCP 1419
V+ P F+A C D C +C+ + +YA CR GV WR P C + CP
Sbjct: 2152 KVLAPATFYAICQQDSCH-------QEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCP 2204
Query: 1420 LERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACP 1479
V++ C CPR C G+ + GC CP V E C+P EAC
Sbjct: 2205 --PSLVYNHCEHGCPRHCDGNVSSCGDHPSE-------GCFCPPDKVMLEGSCVPEEACT 2255
Query: 1480 QVL 1482
Q +
Sbjct: 2256 QCI 2258
Score = 103 bits (257), Expect = 1e-21
Identities = 117/456 (25%), Positives = 166/456 (36%), Gaps = 83/456 (18%)
Query: 744 CLGGFVTCGRRPCEPPGCSHP---LIPSGHCCP--TCQGC-RYHGVTTASGETLPDPLDP 797
C G +CG P E GC P ++ G C P C C GV E P
Sbjct: 2220 CDGNVSSCGDHPSE--GCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQP 2277
Query: 798 TCSLCTCQEG-SMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGS 856
C +CTC G + C +PCP A P C +C + Q E+E
Sbjct: 2278 -CQICTCLSGRKVNCTTQPCPTAKAPT-------CGLCEVARLRQNADQCCPEYE----- 2324
Query: 857 CEWCRCQAGQVSCVRLQCPPLP-CK--LQ--VTERGSCCPRCRGCLAHGEEHPEGSR-WV 910
C VSC PP+P C+ LQ +T G C P C EE S
Sbjct: 2325 -----CVCDPVSC---DLPPVPHCERGLQPTLTNPGECRPNFT-CACRKEECKRVSPPSC 2375
Query: 911 PP------------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEG 958
PP D +C C V+C S+ C C H
Sbjct: 2376 PPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRS 2435
Query: 959 RKYEPGESFQPGADPCEVCICEPQPEGPPSLR---CHRRQCPSLVGCPPSQLLPPGP--Q 1013
Y G+ ++ G C+VC C + LR C ++ C + +L G
Sbjct: 2436 TIYPVGQFWEEG---CDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCG 2492
Query: 1014 HCCPTCAEALSNCSEG-------LLGSELAPPD-PCYTCQCQDLTWLCIHQ----ACPEL 1061
C P+ E ++ G +GS+ A P+ PC +C + Q +CP+L
Sbjct: 2493 RCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQL 2552
Query: 1062 SCPLS----ERHTPPGSCCPVCRAPT-QSCVHQGREVASGERWTVDTCTSCSCMAGT--- 1113
P+ + +CCP CR ++C+ G + G+ +D CT+C CM
Sbjct: 2553 EVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVI 2612
Query: 1114 ----VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP 1145
+ C+ C+P G + + G CC RCLP
Sbjct: 2613 SGFKLECRKTTCNPCPLGYKEEN--NTGECCGRCLP 2646
Score = 79.3 bits (194), Expect = 3e-14
Identities = 125/543 (23%), Positives = 176/543 (32%), Gaps = 158/543 (29%)
Query: 585 PEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDG-SVSCQRLPCP 643
P+ V+L G C P+ G H + E + P PC+ C CL G V+C PCP
Sbjct: 2239 PDKVMLEGSCVPEEACTQCIGEDGVQH-QFLEAWVPDHQPCQICTCLSGRKVNCTTQPCP 2297
Query: 644 PAPC--------AHPRQG--PCCP---------SCD-----GCL--YQGKEFASGERFPS 677
A A RQ CCP SCD C Q GE P+
Sbjct: 2298 TAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPN 2357
Query: 678 PTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPRE 737
T AC C S P +C P P + CC + + C
Sbjct: 2358 FTCACRKEECKRVS----PPSCPPHRLPTLRKTQCCDEYE-C------------------ 2394
Query: 738 PCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTC-QGCRYHGVTTASGETLPDPL- 795
C C+ V+C P G+ T C G TT + LPD +
Sbjct: 2395 ---ACNCVNSTVSC---------------PLGYLASTATNDC---GCTTTT--CLPDKVC 2431
Query: 796 -------------DPTCSLCTCQEGS--------MRCQKKPCPPA--------LCPHPSP 826
+ C +CTC + +C +KPC + L
Sbjct: 2432 VHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECC 2491
Query: 827 GPCFCPVCHSCL------SQGREHQDGEEFEGPAGSCEWCRC---------QAGQVSCVR 871
G C C SQ G ++ P C C Q VSC +
Sbjct: 2492 GRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQ 2551
Query: 872 LQCPPLPCKLQVT-ERGSCCPRCR-----GCLAHGEEHPEGSRWVPPDSACSSCVCHEGV 925
L+ P P Q++ + +CCP CR C+ +G G + C+ GV
Sbjct: 2552 LEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGV 2611
Query: 926 VTCARIQCISSCAQP-------RQGPHDCCPQC--SDCEHEGR-----KYEPGESFQPGA 971
++ +++C + P +CC +C + C + R + E+ Q G
Sbjct: 2612 ISGFKLECRKTTCNPCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDG- 2670
Query: 972 DPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPP---SQLLPPG------PQHCCPTCAEA 1022
C+ C+ G + GCPP + L G P CC TC E
Sbjct: 2671 --CDTHFCKVNERGEYFWE------KRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEP 2722
Query: 1023 LSN 1025
N
Sbjct: 2723 ECN 2725
Score = 77.4 bits (189), Expect = 1e-13
Identities = 135/580 (23%), Positives = 180/580 (31%), Gaps = 142/580 (24%)
Query: 111 PDACTACVCQDGAAHCGPQAHLPHCR-GCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
PD C A C P HC GC ++ GN + C C V +
Sbjct: 2196 PDFC--------AMSCPPSLVYNHCEHGCPRHCD--GNVSSCGDHPSEGCFCPPDKVMLE 2245
Query: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
G SC P E C C E G + + W PC+IC CL G R+
Sbjct: 2246 G----------SCVPE-EACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG----RKVN 2290
Query: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC- 288
C + +P P P C C + + D C C C+P+ C
Sbjct: 2291 CTT------QPCPTAKAPTCGLCEVARLRQ-------NADQC----CPEYECVCDPVSCD 2333
Query: 289 -PPVPCRHPG-----KIPGQCCP----VCDGCEYQGHQYQSQETFR---LQERGLC---- 331
PPVP G PG+C P C E + S R L++ C
Sbjct: 2334 LPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYE 2393
Query: 332 VRCSCQAGEVSC----------EEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEP 381
C+C VSC + C T C LP C + G WE
Sbjct: 2394 CACNCVNSTVSCPLGYLASTATNDCGCTTTTC-LPDK------VCVHRSTIYPVGQFWEE 2446
Query: 382 DGRPCTACVCQDGVPKCGAVLCPPAPCQ-----------HPTQPPGACCPS-CDSCT--- 426
CT +D V C PC+ H + G C PS C+ T
Sbjct: 2447 GCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSP 2506
Query: 427 ---YHSQVYANGQNFTDADSPCHACHC---------QDGTVTCSLVDCP------PTTCA 468
S + G + ++PC C Q V+C ++ P +C
Sbjct: 2507 RGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCK 2566
Query: 469 RPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRC--QEGHAHCQPRPCPRAPC 526
P C R C+L V G++ D C CRC Q G C + C
Sbjct: 2567 TSACCPSCRCERMEACMLNGTVIGPGKTVM--IDVCTTCRCMVQVGVISGFKLECRKTTC 2624
Query: 527 AHPLP-------------GTCCPNDCSGCAFGGKEYPSGADFPHPSDPC--RLCRCLSGN 571
+P P G C P C+ GG+ D D C C+
Sbjct: 2625 -NPCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRD-ETLQDGCDTHFCKVNERG 2682
Query: 572 VQCLARRCVPLP------C----PEPVLLPGECCPQCPAP 601
+R P C + + +PG CC C P
Sbjct: 2683 EYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEP 2722
Score = 73.6 bits (179), Expect = 1e-12
Identities = 115/498 (23%), Positives = 162/498 (32%), Gaps = 127/498 (25%)
Query: 474 PGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRP-----CPRAPCAH 528
P C CP ++ ++H C C + C P CP P
Sbjct: 2196 PDFCAMSCPPSLV----------YNHCEHGCPR-HCDGNVSSCGDHPSEGCFCP--PDKV 2242
Query: 529 PLPGTCCPND-CSGC-AFGGKEYPSGADFPHPSDPCRLCRCLSG-NVQCLARRCVPLPCP 585
L G+C P + C+ C G ++ + PC++C CLSG V C + C P
Sbjct: 2243 MLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAP 2302
Query: 586 EPVLL--------PGECCPQCPA---PAGCPRPGAAHARH--QEYFSPPGDPCRRCLCLD 632
L +CCP+ P C P H Q + PG+ C
Sbjct: 2303 TCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCAC 2362
Query: 633 GSVSCQRL---PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWE 689
C+R+ CPP R+ CC + C C C
Sbjct: 2363 RKEECKRVSPPSCPPHRLPTLRKTQCCDEYE-C---------------------ACNCVN 2400
Query: 690 GSVSCEPKACAPALCPFPARGDC------CPDCDGCEYLGESYLSNQEFPDPREPCNLCT 743
+VSC A A DC C C + Y Q + E C++CT
Sbjct: 2401 STVSCPLGYLAST-----ATNDCGCTTTTCLPDKVCVHRSTIYPVGQFW---EEGCDVCT 2452
Query: 744 CLG--------GFVTCGRRPCEP---PGCSHPLIPSGHCCPTCQGCRYHGVT-------- 784
C C ++PCE G ++ ++ G CC C VT
Sbjct: 2453 CTDMEDAVMGLRVAQCSQKPCEDSCRSGFTY-VLHEGECCGRCLPSACEVVTGSPRGDSQ 2511
Query: 785 ---TASGETLPDPLDPTCSLCTC---------QEGSMRCQKKPCPPALCPHPSPGPC--- 829
+ G P +P C + C Q+ ++ C + P +CP C
Sbjct: 2512 SSWKSVGSQWASPENP-CLINECVRVKEEVFIQQRNVSCPQLEVP--VCPSGFQLSCKTS 2568
Query: 830 -FCPVC-----HSCLSQGREHQDGEEFEGPAGSCEWCRC--QAGQVSCVRLQCPPL---P 878
CP C +C+ G G+ C CRC Q G +S +L+C P
Sbjct: 2569 ACCPSCRCERMEACMLNGTVIGPGKTV--MIDVCTTCRCMVQVGVISGFKLECRKTTCNP 2626
Query: 879 CKLQVTER---GSCCPRC 893
C L E G CC RC
Sbjct: 2627 CPLGYKEENNTGECCGRC 2644
Score = 70.1 bits (170), Expect = 2e-11
Identities = 143/628 (22%), Positives = 208/628 (33%), Gaps = 166/628 (26%)
Query: 640 LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKAC 699
+ CPP+ + + C CDG +S PS C C V E +C
Sbjct: 2201 MSCPPSLVYNHCEHGCPRHCDG------NVSSCGDHPSEG-----CFCPPDKVMLEG-SC 2248
Query: 700 APALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGG-FVTCGRRPCEP 758
P + C C G + + +L + + +PC +CTCL G V C +PC
Sbjct: 2249 VPE--------EACTQCIGEDGVQHQFL--EAWVPDHQPCQICTCLSGRKVNCTTQPC-- 2296
Query: 759 PGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPD---PLDP-TCSLCT---CQEG---- 807
P+ PTC C + + + P+ DP +C L C+ G
Sbjct: 2297 --------PTAK-APTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPT 2347
Query: 808 -----------SMRCQKKPC----PPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEG 852
+ C+K+ C PP+ PH P R+ Q +E+E
Sbjct: 2348 LTNPGECRPNFTCACRKEECKRVSPPSCPPHRLP-------------TLRKTQCCDEYE- 2393
Query: 853 PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSC------CPRCRGCLAHGEEHPEG 906
C C C VSC PL L T C C + C+ +P G
Sbjct: 2394 ----CA-CNCVNSTVSC------PLG-YLASTATNDCGCTTTTCLPDKVCVHRSTIYPVG 2441
Query: 907 SRWVPPDSACSSCVCHE--------GVVTCARIQCISSCAQPRQG------PHDCCPQC- 951
W + C C C + V C++ C SC R G +CC +C
Sbjct: 2442 QFW---EEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSC---RSGFTYVLHEGECCGRCL 2495
Query: 952 -SDCE---------HEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSL-- 999
S CE + G + +PC + C E ++ CP L
Sbjct: 2496 PSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKE-EVFIQQRNVSCPQLEV 2554
Query: 1000 VGCPPSQLLPPGPQHCCPTC-AEALSNCSEGLLGSELAPP-----DPCYTCQCQDLTWL- 1052
CP L CCP+C E + C L G+ + P D C TC+C +
Sbjct: 2555 PVCPSGFQLSCKTSACCPSCRCERMEACM--LNGTVIGPGKTVMIDVCTTCRCMVQVGVI 2612
Query: 1053 ------CIHQACPELSCPLS-ERHTPPGSCCPVCRAPTQSCVHQGREVASGER--WTVDT 1103
C C CPL + G CC C + +G ++ + +R D
Sbjct: 2613 SGFKLECRKTTCN--PCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDG 2670
Query: 1104 CTSCSCMAGTVRCQSQRCSPLSCGP-DKAPALS--------PGSCCPRCLPRPASCMAFG 1154
C + C C P D+ L+ PG+CC C
Sbjct: 2671 CDTHFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTC----------E 2720
Query: 1155 DPHYRTFDGRLLHFQ-GSCSYVLAKDCH 1181
+P RL + + GSC + D H
Sbjct: 2721 EPECNDITARLQYVKVGSCKSEVEVDIH 2748
Score = 67.0 bits (162), Expect = 1e-10
Identities = 108/457 (23%), Positives = 158/457 (34%), Gaps = 95/457 (20%)
Query: 84 LESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQ 143
+ SC HP+ + EG+ +ACT C+ +DG H +A +P + C
Sbjct: 2224 VSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC 2283
Query: 144 TYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECC--PICC-TEGGSHW 200
G + C T + T + C+ + + C P EC P+ C H
Sbjct: 2284 LSGRKVNCTTQPCPTAKAPTCGL-CEVARLRQ--NADQCCPEYECVCDPVSCDLPPVPHC 2340
Query: 201 EHGQE--WTTPGD--PCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNG 256
E G + T PG+ P C C + +C++ S P+ L T C CD
Sbjct: 2341 ERGLQPTLTNPGECRPNFTCACRKE--ECKRVSPPSCPPHRLPTLRKTQC--CD------ 2390
Query: 257 REHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCP--VCDGCEYQG 314
E+ C C N +V C G C P VC
Sbjct: 2391 -EYECA-----------CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVC------V 2432
Query: 315 HQYQSQETFRLQERGLCVRCSCQAGE---VSCEEQECPVTPC-------------ALPAS 358
H+ + E G C C+C E + +C PC
Sbjct: 2433 HRSTIYPVGQFWEEG-CDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECC 2491
Query: 359 GRQLCPACEL-------DGEEF--AEGVQWEPDGRPCTACVC----QDGVPKCGAVLCPP 405
GR L ACE+ D + + G QW PC C ++ + V CP
Sbjct: 2492 GRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCP- 2550
Query: 406 APCQHPTQPPG--------ACCPSC-----DSCTYHSQVYANGQNFTDADSPCHACHC-- 450
+ P P G ACCPSC ++C + V G+ T C C C
Sbjct: 2551 -QLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGK--TVMIDVCTTCRCMV 2607
Query: 451 QDGTVTCSLVDCPPTTC------ARPQSGPGQCCPRC 481
Q G ++ ++C TTC + ++ G+CC RC
Sbjct: 2608 QVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRC 2644
Score = 65.5 bits (158), Expect = 4e-10
Identities = 98/446 (21%), Positives = 141/446 (31%), Gaps = 123/446 (27%)
Query: 138 CSQNGQTYGNGETFSPDACTTCRCLTGAVQCQG---PSCSELNCLESCTP-------PGE 187
C Y G+ F + C C C G CS+ C +SC GE
Sbjct: 2431 CVHRSTIYPVGQ-FWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGE 2489
Query: 188 CCPICCT------------EGGSHWEH-GQEWTTPGDPCRICRCL----EGHIQCRQREC 230
CC C + S W+ G +W +P +PC I C+ E IQ R C
Sbjct: 2490 CCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSC 2549
Query: 231 ASL----CP--YPARPLPGTCCPVC-----DGCFLNGREHRSGEPVGSGDPCSHCRC--- 276
L CP + CCP C + C LNG G+ V D C+ CRC
Sbjct: 2550 PQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMI-DVCTTCRCMVQ 2608
Query: 277 ----ANGSVQCEPLPCPPVPC-----RHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQE 327
+ ++C C P P + G+ G+C P + +G Q + + +
Sbjct: 2609 VGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQ 2668
Query: 328 RGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCT 387
G C C+ E E VT C P C AEG
Sbjct: 2669 DG-CDTHFCKVNERGEYFWEKRVTGC--PPFDEHKC---------LAEG----------- 2705
Query: 388 ACVCQDGVPKCGAVLCPPAPCQHPTQPPGACC-----PSCDSCTYHSQVYANGQNFTDAD 442
G ++ + PG CC P C+ T Q G ++ +
Sbjct: 2706 -----------GKIM----------KIPGTCCDTCEEPECNDITARLQYVKVGSCKSEVE 2744
Query: 443 SPCHACHCQDGTVTCSLVDCPP-----TTCARPQSGPGQCCPRCPDCILEEEVFVDGESF 497
H C + + +D + C+ ++ P Q C +G
Sbjct: 2745 VDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC----------TNGSVV 2794
Query: 498 SHPRDPCQECRCQEGHAHCQPRPCPR 523
H EC+ C PR C +
Sbjct: 2795 YHEVLNAMECK-------CSPRKCSK 2813
Score = 48.5 bits (114), Expect = 5e-05
Identities = 62/272 (22%), Positives = 90/272 (33%), Gaps = 41/272 (15%)
Query: 448 CHCQDGT-VTCSLVDCPPTTCAR-----PQSGPGQCCPRCPDCILEEEVFVDG------- 494
C C DG C + CA PG+C CP + +V++
Sbjct: 613 CSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCP----KGQVYLQCGTPCNLT 668
Query: 495 -ESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGA 553
S S+P + C E C EG C P G C P C + G+ +
Sbjct: 669 CRSLSYPDEECNEA-CLEG-CFCPPG------LYMDERGDCVPKAQCPCYYDGEIFQPED 720
Query: 554 DFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHAR 613
F SD +C C G + C P+ VL + C P
Sbjct: 721 IF---SDHHTMCYCEDGFMHCTMSGVPGSLLPDAVL-SSPLSHRSKRSLSCRPPMVKLVC 776
Query: 614 HQEYFSPPGDPCRRCLCLDGSVSCQRLPC------PPAPCAHPRQGPCCPSCDGCLYQGK 667
+ G C + C + + C + C PP H + C C +QGK
Sbjct: 777 PADNLRAEGLECTKT-CQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCP-CFHQGK 834
Query: 668 EFASGERFPSPTAACHLCLCWEGSVSCEPKAC 699
E+A GE + C+ C+C + +C C
Sbjct: 835 EYAPGE---TVKIGCNTCVCRDRKWNCTDHVC 863
Score = 46.6 bits (109), Expect = 2e-04
Identities = 77/331 (23%), Positives = 107/331 (32%), Gaps = 72/331 (21%)
Query: 104 PEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLT 163
P R+ +AC A + LP+ R C + + +G CL
Sbjct: 574 PRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGR----------ECLC 623
Query: 164 GAVQCQGPSCSELNCLESCTPPGEC---CPICCTEGGSHWEHGQEWTTPGDPCRI-CRCL 219
GA+ +C+ + PG C CP GQ + G PC + CR L
Sbjct: 624 GALASYAAACAGRGVRVAWREPGRCELNCP-----------KGQVYLQCGTPCNLTCRSL 672
Query: 220 EGHIQCRQRECASLCPYPA---RPLPGTCCPVCD-GCFLNGREHRSGEPVGSGDPCSHCR 275
+ C C P G C P C+ +G E E + S D + C
Sbjct: 673 SYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDG-EIFQPEDIFS-DHHTMCY 730
Query: 276 CANGSVQCEPLPCP---------PVPCRHPGKIPGQCCP-----VCDGCEYQGHQYQSQE 321
C +G + C P P H K C P VC
Sbjct: 731 CEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADN---------- 780
Query: 322 TFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPAS---------GRQLCPACELDGEE 372
L+ GL +CQ ++ C C V+ C P + CP C G+E
Sbjct: 781 ---LRAEGLECTKTCQNYDLECMSMGC-VSGCLCPPGMVRHENRCVALERCP-CFHQGKE 835
Query: 373 FAEGVQWEPDGRPCTACVCQDGVPKCGAVLC 403
+A G E C CVC+D C +C
Sbjct: 836 YAPG---ETVKIGCNTCVCRDRKWNCTDHVC 863
Score = 44.3 bits (103), Expect = 0.001
Identities = 88/388 (22%), Positives = 121/388 (31%), Gaps = 111/388 (28%)
Query: 611 HARHQEYFSPPGDPC--RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQ--- 665
H Q+ DPC + +C L P H P P C Y
Sbjct: 556 HGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPL-PYLRNCRYDVCS 614
Query: 666 ---GKEFASGERFPSPTAACH---LCLCWEGSVSCE---PKACAPALCPFPARGDCCPDC 716
G+E G S AAC + + W CE PK C P C C
Sbjct: 615 CSDGRECLCGA-LASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTP----CNLTC 669
Query: 717 DGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ 776
Y P E CN G F PPG + G C P Q
Sbjct: 670 RSLSY-------------PDEECNEACLEGCFC--------PPGLY--MDERGDCVPKAQ 706
Query: 777 -GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCH 835
C Y G + D ++C C++G M C P +L P
Sbjct: 707 CPCYYDGEIFQPEDIFSDHH----TMCYCEDGFMHCTMSGVPGSLLPD------------ 750
Query: 836 SCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRG 895
+ LS H+ CR V+L CP + + E C C+
Sbjct: 751 AVLSSPLSHRSKRSLS--------CR-----PPMVKLVCPADNLRAEGLE---CTKTCQN 794
Query: 896 ----CLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQC 951
C++ G S C+C G+V +C++ + CP
Sbjct: 795 YDLECMSMG--------------CVSGCLCPPGMVRHEN-RCVAL---------ERCP-- 828
Query: 952 SDCEHEGRKYEPGESFQPGADPCEVCIC 979
C H+G++Y PGE+ + G C C+C
Sbjct: 829 --CFHQGKEYAPGETVKIG---CNTCVC 851
Score = 39.3 bits (90), Expect = 0.029
Identities = 40/149 (26%), Positives = 54/149 (36%), Gaps = 32/149 (21%)
Query: 157 TTCRCLTGAVQCQGPSCSEL--NC------LESCTPPGECCPICCTEGGSHWEHGQEWTT 208
T C C G ++C P+ E C L T C P+C G E+
Sbjct: 253 TLCEC-AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPA--------GMEYRQ 303
Query: 209 PGDPC-RICRCLEGHIQCRQRECASLCPYPARPL--PGTC-----CPVCDGCFLNGREHR 260
PC R C+ L + C++R C C P L G C CP C +G+ +
Sbjct: 304 CVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECP----CVHSGKRYP 358
Query: 261 SGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
G + C+ C C N C CP
Sbjct: 359 PGTSLSRD--CNTCICRNSQWICSNEECP 385
Score = 38.9 bits (89), Expect = 0.038
Identities = 35/132 (26%), Positives = 48/132 (36%), Gaps = 43/132 (32%)
Query: 504 CQECRCQEGHAHCQPR-----PCPRAPCAHPLPGTC---C-------------------- 535
C+E +E C+ R P + C HP P C C
Sbjct: 1130 CEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQT 1189
Query: 536 ---PNDCSGCAFGGKEYPSGADFP-HPSDP--CRLCRCLSGNVQCLARRCVPLPCPEP-- 587
P DC C G+ + SG +PSDP C++C C N+ C A C EP
Sbjct: 1190 CVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA-------CQEPGG 1242
Query: 588 VLLPGECCPQCP 599
+++P P P
Sbjct: 1243 LVVPPTDAPVSP 1254
Score = 37.7 bits (86), Expect = 0.084
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 20/102 (19%)
Query: 550 PSGADFPHPSDPC-RLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC---PQCPAPAGCP 605
P+G ++ PC R C+ L N C R CPE LL C +CP C
Sbjct: 296 PAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECP----CV 351
Query: 606 RPGAAHARHQEYFSPPGD----PCRRCLCLDGSVSCQRLPCP 643
G + PPG C C+C + C CP
Sbjct: 352 HSGKRY--------PPGTSLSRDCNTCICRNSQWICSNEECP 385
Score = 37.4 bits (85), Expect = 0.11
Identities = 53/240 (22%), Positives = 76/240 (31%), Gaps = 76/240 (31%)
Query: 786 ASGETLPDPLDPTCSLCTCQEGSMR------CQKKP-------CPPALCPHPSPGPCFCP 832
+SGE + P S C G M+ CQ C P + P P F
Sbjct: 194 SSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP-----FVA 248
Query: 833 VCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPL-----PCKLQV---- 883
+C L C C AG + C CP L C +
Sbjct: 249 LCEKTL---------------------CEC-AGGLECA---CPALLEYARTCAQEGMVLY 283
Query: 884 --TERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPR 941
T+ +C P C P G + S C+ + + +C+ C+ P
Sbjct: 284 GWTDHSACSPVC----------PAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPE 333
Query: 942 QGPHD--CCPQCSDCE--HEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCP 997
D C + ++C H G++Y PG S + C CIC C +CP
Sbjct: 334 GQLLDEGLCVESTECPCVHSGKRYPPGTSL---SRDCNTCICRNS-----QWICSNEECP 385
Score = 36.2 bits (82), Expect = 0.25
Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 32/144 (22%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAVQCQGP-- 171
T C C G C A L + R C+Q G S AC+ C QC P
Sbjct: 253 TLCECA-GGLECACPALLEYARTCAQEGMVLYGWTDHS--ACSPVCPAGMEYRQCVSPCA 309
Query: 172 -SCSELN--------CLESCTPP-------GEC-----CPICCTEGGSHWEHGQEWTTPG 210
+C L+ C++ C+ P G C CP C G + G T+
Sbjct: 310 RTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECP--CVHSGKRYPPG---TSLS 364
Query: 211 DPCRICRCLEGHIQCRQRECASLC 234
C C C C EC C
Sbjct: 365 RDCNTCICRNSQWICSNEECPGEC 388
Score = 34.7 bits (78), Expect = 0.71
Identities = 36/149 (24%), Positives = 50/149 (33%), Gaps = 36/149 (24%)
Query: 274 CRCANGSVQCEPLPCPPV-----PCRHPGKI------PGQCCPVCD-GCEYQ------GH 315
C CA G ++C CP + C G + C PVC G EY+
Sbjct: 255 CECAGG-LECA---CPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCAR 310
Query: 316 QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAE 375
QS + + CSC G++ E T C SG++ P L
Sbjct: 311 TCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLS------ 364
Query: 376 GVQWEPDGRPCTACVCQDGVPKCGAVLCP 404
R C C+C++ C CP
Sbjct: 365 --------RDCNTCICRNSQWICSNEECP 385
Score = 33.9 bits (76), Expect = 1.2
Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 23/96 (23%)
Query: 499 HPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHP 558
H + CQE RC +G + CP G C + C GK YP G
Sbjct: 316 HINEMCQE-RCVDGCS------CPEGQLLDE--GLCVESTECPCVHSGKRYPPGTSL--- 363
Query: 559 SDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGEC 594
S C C C + C C PGEC
Sbjct: 364 SRDCNTCICRNSQWICSNEEC-----------PGEC 388
Score = 31.2 bits (69), Expect = 7.9
Identities = 41/169 (24%), Positives = 56/169 (33%), Gaps = 52/169 (30%)
Query: 287 PCPPVPCRHPGKIPGQCCPV--CDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE 344
P V C+HP + CPV +GC C G++ E
Sbjct: 1151 PACQVTCQHPEPL---ACPVQCVEGCH----------------------AHCPPGKILDE 1185
Query: 345 EQECPVTPCALPASGRQLCPACELDGEEFAEG--VQWEP-DGRPCTACVCQDGVPKCGAV 401
+ V P + CP CE+ G FA G V P D C C C C A
Sbjct: 1186 LLQTCVDP--------EDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA- 1236
Query: 402 LCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHC 450
CQ +P G P D+ + +Y ++ P H +C
Sbjct: 1237 ------CQ---EPGGLVVPPTDAPVSPTTLYVE----DISEPPLHDFYC 1272
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 217 bits (553), Expect = 6e-56
Identities = 286/1149 (24%), Positives = 378/1149 (32%), Gaps = 320/1149 (27%)
Query: 211 DPCRICRCLEGHIQ------CRQRECASLCPYPARPLPGTCCPVC-----DGCFLNGREH 259
D C+ CRC G I CR +CA + CCP C C + H
Sbjct: 44 DSCQSCRC-HGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIH 102
Query: 260 RSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHP--GKIP-GQCCPVCDG----CEY 312
G S PCS C C +G V+C P PCPP+ C H IP G CCPVC G C Y
Sbjct: 103 EHGTEWASS-PCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSY 161
Query: 313 QGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPC-------ALPASGRQLCPA 365
+GH +Q E +RL C +C C+ G C +C C +P C A
Sbjct: 162 EGHVFQDGEDWRLSR---CAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCSA 218
Query: 366 --CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPC---QHPTQPPGACCP 420
C G+ + G QW + CT C+C G +C C P C Q + G CC
Sbjct: 219 RSCSAAGQVYEHGEQWSENA--CTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCE 276
Query: 421 SC----DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQS---G 473
C SC+Y V + + S C C C G VTC +C CAR +
Sbjct: 277 ECVSPAGSCSYDGVVRYQDEMW--KGSACEFCMCDHGQVTCQTGECAKVECARDEELIHL 334
Query: 474 PGQCCPRCPD----CILEE----------EVFVDGESFSHPRDPCQECRCQEGHAHC-QP 518
G+CCP C C+ EE EV E PC+ C C+ C +P
Sbjct: 335 DGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEP 394
Query: 519 R--PCPRAPCAHPLPGTCCPN--------DCSGCA-----------------FGGKEYPS 551
PCP A + G CCP+ DC C+ G +
Sbjct: 395 SCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSC 454
Query: 552 GADFPHPSDPCRLCR-----CLSGNVQCLARRCVPLPCPEPVLL-PGECCPQCPAPAGCP 605
G F C C+ C SG ++C + C P+L+ G+C P C
Sbjct: 455 GLGFYQAGSLCLACQPQCSTCTSG-LECSS-------CQPPLLMRHGQCVPTCGDGFYQD 506
Query: 606 RPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCA---HPRQGPCC---PSC 659
R A H+ G + CL + R + C + RQG C SC
Sbjct: 507 RHSCA-VCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQGTCSACDQSC 565
Query: 660 DGC---------------LYQGKEFAS--GERFPSPTAACHLCLCWEGSVSCE---PKAC 699
D C L+ GK + G + T C +C SC P C
Sbjct: 566 DSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCK--VCHNSCASCSGPTPSHC 623
Query: 700 APALCPFPAR-GDCCPDCDGCEYLGESYLSNQEFPDPREPCNLC--TCLGGFVTCGRRPC 756
P R G C P C GE + S+ C C +CL G P
Sbjct: 624 TACSPPKALRQGHCLPRC------GEGFYSDHGV------CKACHSSCL---ACMGPAPS 668
Query: 757 EPPGCSHPL------------IPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTC 804
GC P IPSG C C+ Y L+ T C
Sbjct: 669 HCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFY--------------LESTGICEAC 714
Query: 805 QEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQ---GREHQDGEEFEGPAGSCEWCR 861
+ RC K P C GP + CLSQ G HQ+G
Sbjct: 715 HQSCFRCAGK--SPHNC--TDCGPSHVLLDGQCLSQCPDGYFHQEG-------------- 756
Query: 862 CQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVC 921
SC C P CR C HG P +S C SC
Sbjct: 757 ------SCT-----------------ECHPTCRQC--HG----------PLESDCISCYP 781
Query: 922 HEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEP 981
H ++ C +SC + + + C+DC H C+ C +
Sbjct: 782 H---ISLTNGNCRTSCREEQF--LNLVGYCADCHH----------------LCQHCAADL 820
Query: 982 QPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAE-------ALSNCSEGLLGSE 1034
G LRC L+G HC P C A C +
Sbjct: 821 HNTGSICLRCQNAHY-LLLG-----------DHCVPDCPSGYYAERGACKKCHSSCRTCQ 868
Query: 1035 LAPPDPCYTCQCQDLTWLCIHQACPELSC----PLSERH------TPPGSC-----CPVC 1079
P C +C D + H +C L + H T GSC C C
Sbjct: 869 GRGPFSCSSC---DTNLVLSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCDSQASCTSC 925
Query: 1080 RAPTQ-----SCVHQGREVASGERWTVDTCT----SCSCMAGTVRCQSQRCSPLSCGPDK 1130
R P + C ++ ++ +TC SCS +G ++ +C
Sbjct: 926 RDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCM-------D 978
Query: 1131 APALSPGSCCPRCLPR----------PASCMAFGDPHYRT-FDGRLLHFQGSCSYVLAKD 1179
L G+C +CL + C+ PH T G L + C ++
Sbjct: 979 GYVLQDGACVEQCLSSFYQDSGLCKCDSYCLQCQGPHECTRCKGPFLLLEAQC----VQE 1034
Query: 1180 CHSGDFSVH 1188
C G F+ H
Sbjct: 1035 CGKGYFADH 1043
Score = 167 bits (424), Expect = 5e-41
Identities = 259/1029 (25%), Positives = 333/1029 (32%), Gaps = 278/1029 (27%)
Query: 94 PQCWGLGR-------AWPEGARWEPDACTACVCQDGAAHCG------------------P 128
P C GLG+ + +G W C C+C++G A C P
Sbjct: 150 PVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVP 209
Query: 129 QAHLPHC--RGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNC---LESCT 183
P C R CS GQ Y +GE +S +ACTTC C G V+C +C L C
Sbjct: 210 GKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRAR 269
Query: 184 PPGECCPICCTEGGSHWEHG----QEWTTPGDPCRICRCLEGHIQCRQRECASL-CPYPA 238
G+CC C + GS G Q+ G C C C G + C+ ECA + C
Sbjct: 270 RHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDE 329
Query: 239 R--PLPGTCCPVC-----------DGCFLNGREHR-----SGEPVGSGDPCSHCRCANGS 280
L G CCP C G F++ GE G PC C C
Sbjct: 330 ELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDG-PCKVCECRGAQ 388
Query: 281 VQCEPLPCPPVPCRHPG-KIPGQCCPVCDG----------CEYQGHQYQSQETFRLQERG 329
V C CPP P ++ GQCCP C + H Q+ +L + G
Sbjct: 389 VTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNG 448
Query: 330 LCVRCSC-----QAGE--VSCEEQ--------ECPVTPCALPASGRQLCPACELDG---- 370
CV SC QAG ++C+ Q EC L Q P C DG
Sbjct: 449 WCVH-SCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTCG-DGFYQD 506
Query: 371 -------EEFAEGVQWEPDGRPCTAC-----VCQDG--VPKCGAVLC----PPAPCQHPT 412
E G W P + C AC V +DG CG + C
Sbjct: 507 RHSCAVCHESCAGC-WGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQGTCSACDQSC 565
Query: 413 QPPGACCPSCDSCTYHSQVY-------ANGQNFTDADSPCHACHCQDGTVTCS-LVDCPP 464
G P C +CT + ++ G + DA C CH + +CS
Sbjct: 566 DSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCH--NSCASCSGPTPSHC 623
Query: 465 TTCARPQS-GPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPR 523
T C+ P++ G C PRC GE F C+ C H+ C
Sbjct: 624 TACSPPKALRQGHCLPRC------------GEGFYSDHGVCKAC-----HSSC------- 659
Query: 524 APCAHPLPGTCCPNDCSGC--AFGGKEYPSGADFPHPSDPC-RLCR----------CLSG 570
C P P+ C+GC G + +D PS C CR C +
Sbjct: 660 LACMGP-----APSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLESTGICEAC 714
Query: 571 NVQCLARRCV---PLPC----PEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGD 623
+ C RC P C P VLL G+C QCP HQE
Sbjct: 715 HQSCF--RCAGKSPHNCTDCGPSHVLLDGQCLSQCP----------DGYFHQEGSCTECH 762
Query: 624 P-CRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC 682
P CR+C G + + C P G C SC E+F + C
Sbjct: 763 PTCRQC---HGPLESDCISC--YPHISLTNGNCRTSC-----------REEQFLNLVGYC 806
Query: 683 ----HLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPD---- 734
HLC + CA L G C C YL L + PD
Sbjct: 807 ADCHHLC-----------QHCAADL---HNTGSICLRCQNAHYL---LLGDHCVPDCPSG 849
Query: 735 ---PREPCNLCTCLGGFVTC-GRRPCEPPGCSHPLIPS--GHCCPTCQGCRYHGVTTASG 788
R C C TC GR P C L+ S G C TC Y
Sbjct: 850 YYAERGACK--KCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHY-----LDD 902
Query: 789 ETLPDPLDPTCSLCTCQEGSMRCQ--KKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQD 846
+ P + C C Q C+ K C + S P +
Sbjct: 903 NHVCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYL-------------- 948
Query: 847 GEEFEGPAGSCEW-CRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPE 905
+ C+W C +G + LQC V + G+C +C +
Sbjct: 949 -DFSTNTCKECDWSCSACSGPLKTDCLQC----MDGYVLQDGACVEQCLSSFY------Q 997
Query: 906 GSRWVPPDSACSSCVCHEGVVTCAR---------IQCISSCAQ---PRQGPHDC--CPQ- 950
S DS C C +G C R QC+ C + H C CPQ
Sbjct: 998 DSGLCKCDSYCLQC---QGPHECTRCKGPFLLLEAQCVQECGKGYFADHAKHKCTACPQG 1054
Query: 951 CSDCEHEGR 959
C C H R
Sbjct: 1055 CLQCSHRDR 1063
Score = 137 bits (345), Expect = 8e-32
Identities = 100/353 (28%), Positives = 131/353 (37%), Gaps = 40/353 (11%)
Query: 819 ALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLP 878
A+ PH S G +C+ Q D ++ SC+ CRC V C C
Sbjct: 18 AVLPHHSEG--------ACVYQDSLLADATIWK--PDSCQSCRCHGDIVICKPAVCRNPQ 67
Query: 879 CKLQVTE-----RGSCCPRC-----RGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTC 928
C + E CCP C C + H G+ W S CS C C+ G V C
Sbjct: 68 CAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIHEHGTEWA--SSPCSVCSCNHGEVRC 125
Query: 929 ARIQCIS-SCAQPRQG---PHDCCPQC----SDCEHEGRKYEPGESFQPGADPCEVCICE 980
C SC CCP C C +EG ++ GE ++ C C+C
Sbjct: 126 TPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWR--LSRCAKCLCR 183
Query: 981 PQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTC-AEALSNCSEGLLGSELAPPD 1039
+C QC L C + + P CCP C A + S + E +
Sbjct: 184 NGVA-----QCFTAQCQPLF-CNQDETVVRVPGKCCPQCSARSCSAAGQVYEHGEQWSEN 237
Query: 1040 PCYTCQCQDLTWLCIHQACPELSCPLSE-RHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
C TC C C QAC L C + R G CC C +P SC + G E
Sbjct: 238 ACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEM 297
Query: 1099 WTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCM 1151
W C C C G V CQ+ C+ + C D+ G CCP C+ R C+
Sbjct: 298 WKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCV 350
Score = 133 bits (335), Expect = 1e-30
Identities = 88/265 (33%), Positives = 114/265 (43%), Gaps = 30/265 (11%)
Query: 912 PDSACSSCVCHEGVVTCARIQCISSCAQPRQGP------HDCCPQC-----SDCEHEGRK 960
PDS C SC CH +V C C + +G + CCP+C C HE +
Sbjct: 43 PDS-CQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKI 101
Query: 961 YEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQL--LPPGPQHCCPT 1018
+E G + + PC VC C +RC + CP L C +L +P G CCP
Sbjct: 102 HEHGTEW--ASSPCSVCSCNHG-----EVRCTPQPCPPL-SCGHQELAFIPEGS--CCPV 151
Query: 1019 CAEALSNCS-EGLL--GSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTP-PGS 1074
C CS EG + E C C C++ C C L C E PG
Sbjct: 152 CVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGK 211
Query: 1075 CCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPAL 1134
CCP C A +SC G+ GE+W+ + CT+C C G VRC Q C PL CG ++ A
Sbjct: 212 CCPQCSA--RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRAR 269
Query: 1135 SPGSCCPRCLPRPASCMAFGDPHYR 1159
G CC C+ SC G Y+
Sbjct: 270 RHGQCCEECVSPAGSCSYDGVVRYQ 294
Score = 82.0 bits (201), Expect = 4e-15
Identities = 44/132 (33%), Positives = 54/132 (40%), Gaps = 4/132 (3%)
Query: 1038 PDPCYTCQCQDLTWLCIHQACPELSCPLSERHT---PPGSCCPVCRAPTQ-SCVHQGREV 1093
PD C +C+C +C C C + CCP C T SC H+ +
Sbjct: 43 PDSCQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIH 102
Query: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
G W C+ CSC G VRC Q C PLSCG + + GSCCP C+ C
Sbjct: 103 EHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYE 162
Query: 1154 GDPHYRTFDGRL 1165
G D RL
Sbjct: 163 GHVFQDGEDWRL 174
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 211 bits (538), Expect = 3e-54
Identities = 167/497 (33%), Positives = 211/497 (42%), Gaps = 72/497 (14%)
Query: 1015 CCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWLCIHQACPELSCPLSERHTPPG 1073
C TC+ S L + L PD C CQC D +L QAC P
Sbjct: 3943 CADTCSLGCS-----ALSAPLQCPDGCAEGCQC-DSGFLYNGQAC-----------VPIQ 3985
Query: 1074 SCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAG-TVRCQSQRCSP-------- 1123
C C H G + +D C C+C G V CQ C P
Sbjct: 3986 QC---------GCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSG 4036
Query: 1124 --LSC---GPDKAPALSPGSCCPR------CLPR-PASCMAFGDPHYRTFDGRLLHFQGS 1171
LSC P P C CLP A+C +GDPHY +FDGR FQG+
Sbjct: 4037 GILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGT 4096
Query: 1172 CSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD--GAV 1222
C+YVLA G F+V N +RG V++ + V V + + +D G V
Sbjct: 4097 CNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKV 4156
Query: 1223 TVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
V+G ALP + + + V +L A GLQV +D +V+V++P SY G CGL
Sbjct: 4157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 4216
Query: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
CGN + +D P G L PS +G SW+ W R P +
Sbjct: 4217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WDPLCWDECRGSCPTCPEDRLEQY 4274
Query: 1342 EANARCGVLKS---SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASH 1398
E CG L S PF+ CHA VPPE FF CV D+C G LC AL +Y +
Sbjct: 4275 EGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM---GGGDRDILCKALASYVAA 4331
Query: 1399 CRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP 1457
C+ AGV WR C + CP ++ CGPPCP +C PL A C PCV
Sbjct: 4332 CQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGPPCPASC-PSPAPL-TTPAVCEGPCVE 4387
Query: 1458 GCQCPAGLVEHEAHCIP 1474
GCQC AG V C+P
Sbjct: 4388 GCQCDAGFVLSADRCVP 4404
Score = 210 bits (535), Expect = 7e-54
Identities = 166/497 (33%), Positives = 210/497 (42%), Gaps = 72/497 (14%)
Query: 1015 CCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWLCIHQACPELSCPLSERHTPPG 1073
C TC+ S L + L PD C CQC D +L QAC P
Sbjct: 2742 CADTCSLGCS-----ALSAPLQCPDGCAEGCQC-DSGFLYNGQAC-----------VPIQ 2784
Query: 1074 SCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAG-TVRCQSQRCSP-------- 1123
C C H G + +D C C+C G V CQ C P
Sbjct: 2785 QC---------GCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSG 2835
Query: 1124 --LSC---GPDKAPALSPGSCCPR------CLPR-PASCMAFGDPHYRTFDGRLLHFQGS 1171
LSC P P C CLP A+C +GDPHY +FDGR FQG+
Sbjct: 2836 GILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGT 2895
Query: 1172 CSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD--GAV 1222
C+YVLA G F+V N +RG V++ + V V + + +D G V
Sbjct: 2896 CNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKV 2955
Query: 1223 TVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
V+G ALP + + + V +L A GLQV +D +V+V++P SY G CGL
Sbjct: 2956 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 3015
Query: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
CGN + +D P G L PS +G SW+ W R P +
Sbjct: 3016 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WDPLCWDECRGSCPTCPEDRLEQY 3073
Query: 1342 EANARCGVL---KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASH 1398
E CG L PF+ CHA VPPE FF CV D+C G LC AL +Y +
Sbjct: 3074 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM---GGGDRDILCKALASYVAA 3130
Query: 1399 CRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP 1457
C+ AGV WR C + CP ++ CGPPCP +C PL A C PCV
Sbjct: 3131 CQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGPPCPASC-PSPAPL-TTPAVCEGPCVE 3186
Query: 1458 GCQCPAGLVEHEAHCIP 1474
GCQC AG V C+P
Sbjct: 3187 GCQCDAGFVLSADRCVP 3203
Score = 207 bits (527), Expect = 6e-53
Identities = 170/517 (32%), Positives = 216/517 (41%), Gaps = 80/517 (15%)
Query: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
CP + CPP+ + C TC+ S S APP QCQD
Sbjct: 1528 CP--MECPPNSHY----ELCADTCSLGCSALS--------APP------QCQD------- 1560
Query: 1056 QACPELSCPLSERHTPPGSCCPVCRAPTQSC--VHQGREVASGERWTVDTCTS-CSCMAG 1112
C E C G C P Q C H G + +D C C+C AG
Sbjct: 1561 -GCAE-GCQCDSGFLYNGQAC----VPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG 1614
Query: 1113 T-VRCQSQRCSP----------LSC---GPDKAPALSPGSCCPR------CLPR-PASCM 1151
+ CQ C P LSC P P C CLP A+C
Sbjct: 1615 KGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCW 1674
Query: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQE 1204
+GDPHY +FDGR FQG+C+YVLA G F+V N +RG V++ +
Sbjct: 1675 LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 1734
Query: 1205 VAVLLGDMAVRLLQD--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWD 1261
V V + + +D G V V+G ALP + + + V +L A GLQV +D
Sbjct: 1735 VTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYD 1794
Query: 1262 GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR 1321
+V+V++P SY G CGLCGN + +D P G L PS +G SW+ W
Sbjct: 1795 WNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WDPL 1852
Query: 1322 PCSAGREVDPCRAAGYRARREANARCGVL---KSSPFSRCHAVVPPEPFFAACVYDLCAC 1378
R P + E CG L PF+ CHA VPPE FF CV D+C
Sbjct: 1853 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM- 1911
Query: 1379 GPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTC 1437
G LC AL +Y + C+ AGV WR C + CP ++ CG PCP +C
Sbjct: 1912 --GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGSPCPASC 1967
Query: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIP 1474
PL A C PCV GCQC AG V C+P
Sbjct: 1968 -PSPAPL-TTPAVCEGPCVEGCQCDAGFVLSADRCVP 2002
Score = 207 bits (526), Expect = 8e-53
Identities = 183/560 (32%), Positives = 237/560 (42%), Gaps = 85/560 (15%)
Query: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 4657 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 4711
Query: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
A ++ C + G E PD C C LC +CP +SCP + P C
Sbjct: 4712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC-GDSCP-VSCPSL---SAPEGCE 4766
Query: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCM-------AGTV-----RCQSQ-R 1120
CR + CV V SG DTC C C+ G V C+ +
Sbjct: 4767 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
Query: 1121 CSP---------LSCGPDKAPALSPG--SC----CPRCLPRPASCMAFGDPHYRTFDGRL 1165
C P +CGP + L G +C C RCL A G HY T DGR+
Sbjct: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCL-------ANGGIHYITLDGRV 4871
Query: 1166 LHFQGSCSYVLAKDCH----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGA 1221
GSCSYVLA+ CH DFS+ + + G Q + V + V L Q
Sbjct: 4872 YDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQQ 4926
Query: 1222 VTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
VTVDG VALP + + V G ++L GL++L+DG + + +S+P ++GR CGL
Sbjct: 4927 VTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 4985
Query: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
CGNFNG DD P G S FG +W+ + G G G + P A A
Sbjct: 4986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWR-APGSSKGCGEGCGPQGCPVCLAEETAPY 5044
Query: 1342 EANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHC 1399
E+N CG L++ PF+ C AV+ P +F CVYDLCA A LC +L AY + C
Sbjct: 5045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLAAYTAAC 5101
Query: 1400 RQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPG 1458
+ AGV WR + C + CP + C RTC L L C C G
Sbjct: 5102 QAAGVAVKPWRTDSFCPLHCPAHSHYSI------CTRTCQGSCAALSGLTG-CTTRCFEG 5154
Query: 1459 CQCPAGLVEHEAHCIPPEAC 1478
C+C + + CIP + C
Sbjct: 5155 CECDDRFLLSQGVCIPVQDC 5174
Score = 200 bits (508), Expect = 1e-50
Identities = 179/566 (31%), Positives = 233/566 (41%), Gaps = 83/566 (14%)
Query: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 2255 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 2309
Query: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
A ++ C + G E PD C + C LC +CP SCP + P C
Sbjct: 2310 VATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC-GDSCPG-SCPSL---SAPEGCE 2364
Query: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCMA------------------GTVR 1115
CR + CV V SG DTC C C+ R
Sbjct: 2365 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 2416
Query: 1116 CQSQ---RCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPHYRTFDGRLLHFQGS 1171
C+ C P SCGP + S GS C+ +C A GDPHY TFDGR F G+
Sbjct: 2417 CREGGEVSCEPSSCGPHETCRPSGGSL--GCVAVGSTTCQASGDPHYTTFDGRRFDFMGT 2474
Query: 1172 CSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ-DGAVTVDG 1226
C YVLA+ C + F+V N G V+ T+ + V + + +RL Q VTV+G
Sbjct: 2475 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNG 2534
Query: 1227 HPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNF 1285
+ LP L + G V++ GL+V +D V V+VPG+Y CGLCGN+
Sbjct: 2535 VDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNY 2594
Query: 1286 NGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAA---------G 1336
NG +DD Q P G + FGNSW E + P PC P
Sbjct: 2595 NGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLPPPTCPPGSEGCIPSEECPPE 2651
Query: 1337 YRARREANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEA 1394
+ + CG+L S P S CH +V P+ C++DLC G S LC + A
Sbjct: 2652 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLS---ILCSNIHA 2708
Query: 1395 YASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCV 1452
Y S C+ AG V P WR T C + CP + ++ C C C PL C
Sbjct: 2709 YVSACQAAGGQVEP-WRNETFCPMECP--QNSHYELCADTCSLGCSALSAPL-----QCP 2760
Query: 1453 RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
C GCQC +G + + C+P + C
Sbjct: 2761 DGCAEGCQCDSGFLYNGQACVPIQQC 2786
Score = 200 bits (508), Expect = 1e-50
Identities = 180/566 (31%), Positives = 234/566 (41%), Gaps = 83/566 (14%)
Query: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 3456 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 3510
Query: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
A ++ C + G E PD C + C LC +CP SCP + P C
Sbjct: 3511 VATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC-GDSCPG-SCPSL---SAPEGCE 3565
Query: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCMA------------------GTVR 1115
CR + CV V SG DTC C C+ R
Sbjct: 3566 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 3617
Query: 1116 CQSQ---RCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPHYRTFDGRLLHFQGS 1171
C+ C P SCGP + S GS C+ +C A GDPHY TFDG F G+
Sbjct: 3618 CREGGEVSCEPSSCGPHETCRPSGGSL--GCVAVGSTTCQASGDPHYTTFDGHRFDFMGT 3675
Query: 1172 CSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ-DGAVTVDG 1226
C YVLA+ C + F+V N G V+ T+ + V + + +RL Q VTV+G
Sbjct: 3676 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNG 3735
Query: 1227 HPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNF 1285
+ LP L + G V++ GL+V +D V V+VPG+Y CGLCGN+
Sbjct: 3736 VDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNY 3795
Query: 1286 NGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPC---------SAGREVDPCRAAG 1336
NG +DD Q P G + FGNSW E + P PC SAG
Sbjct: 3796 NGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLPPPTCPPGSAGCIPSDKCPPE 3852
Query: 1337 YRARREANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEA 1394
+ + CG+L S P S CH +V P+ C++DLC G S LC + A
Sbjct: 3853 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLS---ILCSNIHA 3909
Query: 1395 YASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCV 1452
Y S C+ AG V P WR T C + CP + ++ C C C PL C
Sbjct: 3910 YVSACQAAGGHVEP-WRNETFCPMECP--QNSHYELCADTCSLGCSALSAPL-----QCP 3961
Query: 1453 RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
C GCQC +G + + C+P + C
Sbjct: 3962 DGCAEGCQCDSGFLYNGQACVPIQQC 3987
Score = 199 bits (507), Expect = 1e-50
Identities = 132/388 (34%), Positives = 177/388 (45%), Gaps = 43/388 (11%)
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
+C C AG QRC + KA ++ + A C A GDPHY TFD
Sbjct: 443 SCEGMQCAAG------QRCQVVG---GKAGCVAEST---------AVCRAQGDPHYTTFD 484
Query: 1163 GRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ 1218
GR G+CSY + + C D FSV N+ RG V++ V V +V L +
Sbjct: 485 GRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTR 544
Query: 1219 D--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQ 1275
G V VD LP L E L V G ++ GL V +D Q+ +S+P +Q
Sbjct: 545 GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQ 604
Query: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PCRA 1334
+ CGLCGN+NG DD P+G L P F +SW++ +G + C G + + P
Sbjct: 605 DQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY---LCEDGCQNNCPACT 661
Query: 1335 AGYRARREANARCGVLK--SSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
G E + CG+L PF+ CH + P PF CVYDLC G LC L
Sbjct: 662 PGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG---GERLSLCRGL 718
Query: 1393 EAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
AYA C + G++ WR P C + CP ++ CGP CP +C P ++C
Sbjct: 719 SAYAQACLELGISVGDWRSPANCPLSCPANSR--YELCGPACPTSCNGAAAP-----SNC 771
Query: 1452 V-RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
RPCV GC C G V C+P +C
Sbjct: 772 SGRPCVEGCVCLPGFVASGGACVPASSC 799
Score = 196 bits (499), Expect = 1e-49
Identities = 169/577 (29%), Positives = 236/577 (40%), Gaps = 86/577 (14%)
Query: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
+C C C + + G F C P G P CH P G
Sbjct: 1856 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLAPGTGGPFTTCHAHVPPESFFKG 1904
Query: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 1905 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCP 1964
Query: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
SCP T P G C C+ + R V A E W
Sbjct: 1965 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 2023
Query: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 2024 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 2079
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Y T DG +FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 2080 YVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 2139
Query: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
++ L + VDG V LPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 2140 SLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 2199
Query: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
P +Y G CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 2200 PAAYAGSLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 2250
Query: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 2251 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 2305
Query: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
LC A+ Y + C+ AG WR P C CP ++ CG CP +C +
Sbjct: 2306 -----LCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSH--YELCGDSCPGSCPSLS 2358
Query: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
P G C C GC C AG V C+P C
Sbjct: 2359 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 2390
Score = 195 bits (496), Expect = 2e-49
Identities = 169/577 (29%), Positives = 235/577 (40%), Gaps = 86/577 (14%)
Query: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
+C C C + + G F C P G P CH P G
Sbjct: 3057 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLAPGTGGPFTTCHAHVPPESFFKG 3105
Query: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 3106 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 3165
Query: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
SCP T P G C C+ + R V A E W
Sbjct: 3166 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 3224
Query: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 3225 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 3280
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 3281 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 3340
Query: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
++ L + VDG V LPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 3341 SLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 3400
Query: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
P +Y G CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 3401 PAAYAGSLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 3451
Query: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 3452 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 3506
Query: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
LC A+ Y + C+ AG WR P C CP ++ CG CP +C +
Sbjct: 3507 -----LCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSH--YELCGDSCPGSCPSLS 3559
Query: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
P G C C GC C AG V C+P C
Sbjct: 3560 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 3591
Score = 195 bits (496), Expect = 2e-49
Identities = 169/577 (29%), Positives = 236/577 (40%), Gaps = 86/577 (14%)
Query: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
+C C C + + G F C P G P CH P G
Sbjct: 4258 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLSSGTGGPFTTCHAHVPPESFFKG 4306
Query: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 4307 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 4366
Query: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
SCP T P G C C+ + R V A E W
Sbjct: 4367 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 4425
Query: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 4426 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 4481
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 4541
Query: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
++ L + VDG VALPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 4542 SLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 4601
Query: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
P +Y CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 4602 PAAYAASLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 4652
Query: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 4653 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 4707
Query: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
LC A+ Y + C+ AG WR P C + CP ++ CG CP +C +
Sbjct: 4708 -----LCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSH--YELCGDSCPVSCPSLS 4760
Query: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
P G C C GC C AG V C+P C
Sbjct: 4761 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 4792
Score = 195 bits (495), Expect = 3e-49
Identities = 156/463 (33%), Positives = 205/463 (44%), Gaps = 58/463 (12%)
Query: 1055 HQACPELSCPLSERHTP-PGSCCPVCRA----------------PTQSC--VHQGREVAS 1095
++AC CPLS P PG C C P SC VHQG
Sbjct: 1142 YEAC-SYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
Query: 1096 GERWTVDT-CTS-CSCM-AGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CM 1151
G+ + C S C C G V C+S SCGP +A S GS C+ +S C
Sbjct: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESS-----SCGPHEACQPSGGSL--GCVAVGSSTCQ 1253
Query: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAV 1207
A GDPHY TFDGR F G+C YVLA+ C + F+V N G V+ T+ + V
Sbjct: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
Query: 1208 LLGDMAVRLLQ-DGAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQ 1265
+ + +RL Q VTV+G + LP L + G V++ GL+V +D
Sbjct: 1314 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQ---VSEGLWPGRP 1322
V V+VPG+Y + CGLCGN+NG +DD Q P G + FGNSW+ P P
Sbjct: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 1433
Query: 1323 CSAGRE-VDPCRAAGYRARREANAR--CGVLKS--SPFSRCHAVVPPEPFFAACVYDLCA 1377
C G E P ++ CG+L S P S CH +V P+ C++DLC
Sbjct: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493
Query: 1378 CGPGSSADACLCDALEAYASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPR 1435
G S LC + AY S C+ AG V P WR T C + CP ++ C C
Sbjct: 1494 GGGNLS---ILCSNIHAYVSACQAAGGHVEP-WRTETFCPMECPPNSH--YELCADTCSL 1547
Query: 1436 TCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
C P C C GCQC +G + + C+P + C
Sbjct: 1548 GCSALSAP-----PQCQDGCAEGCQCDSGFLYNGQACVPIQQC 1585
Score = 192 bits (488), Expect = 2e-48
Identities = 144/423 (34%), Positives = 195/423 (46%), Gaps = 41/423 (9%)
Query: 1073 GSCCPVCRAPTQSCVHQGREVASGER-WTVDTCTS-CSCMAGT--VRCQSQRCSPLSCGP 1128
G+C P A + C QG ++A G+ W + C C+C T V C+ ++ SC
Sbjct: 791 GACVP---ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ----SCPA 843
Query: 1129 DKAPALSPG--SCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD-- 1184
+ ++ G C P R +C GDPHY +FDGR F G+C+Y+L C
Sbjct: 844 GERCSVQNGLLGCYP---DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 1185 --FSVHVTNDDRGRSGVAWTQEVAVLLGDM--AVRLLQDGAVTVDGHPVALPF-LQEPLL 1239
F V V N+ RG V++T+ V V + AVR G V VD LPF + +
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
Query: 1240 YVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGL 1299
V +G ++ GL V +D ++V VP SY CGLCGNFNG DDL G
Sbjct: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
Query: 1300 LLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR-EANARCGVL--KSSPFS 1356
+ AFGNSWQ E PG C A D + A++ ++ CG+L PF
Sbjct: 1021 QAANALAFGNSWQ--EETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCV 1415
CH+ + P+ CVYD C PG S LCDAL YA+ C+ AG T WR LC
Sbjct: 1077 ECHSKLDPQGAVRDCVYDRCLL-PGQSGP--LCDALATYAAACQAAGATVHPWRSEELCP 1133
Query: 1416 VGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPP 1475
+ CP ++ C CP +C + +P G C C GC C G C+P
Sbjct: 1134 LSCPPHSH--YEACSYGCPLSCGDLPVPGG-----CGSECHEGCVCDEGFALSGESCLPL 1186
Query: 1476 EAC 1478
+C
Sbjct: 1187 ASC 1189
Score = 51.2 bits (121), Expect = 7e-06
Identities = 68/227 (29%), Positives = 81/227 (35%), Gaps = 40/227 (17%)
Query: 558 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA----PAGCPRPGAA-HA 612
P P R C + Q R CV C LLPG+ P C A A C GA H
Sbjct: 1071 PKGPFRECHSKL-DPQGAVRDCVYDRC----LLPGQSGPLCDALATYAAACQAAGATVHP 1125
Query: 613 RHQEYFSPPGDPCRRCL--CLDGS-VSCQRLPCPPAPCAHPRQGPCCP------------ 657
E P P C G +SC LP P + +G C
Sbjct: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLP 1185
Query: 658 --SCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKACAPALCPFPARGDCCP 714
SC GC++QG G+ F LC C EG VSCE +C P P+ G
Sbjct: 1186 LASC-GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSL-- 1242
Query: 715 DCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGRRP 755
GC +G S P D R + TC+ TCG RP
Sbjct: 1243 ---GCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1286
Score = 50.8 bits (120), Expect = 1e-05
Identities = 80/302 (26%), Positives = 103/302 (34%), Gaps = 72/302 (23%)
Query: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 2239 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 2283
Query: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
P C A + +P G P+ + C + Q R P CP
Sbjct: 2284 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLREWRRPDFCPFQCPAH 2340
Query: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
L G+ CP CP AP GC CR C+C G V
Sbjct: 2341 SHYELCGDSCPGSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 2383
Query: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKAC 699
P C GCL+ + + G+ F LC C EG VSCEP +C
Sbjct: 2384 CVPVGQC-------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 2430
Query: 700 APALCPFPARGDCCPDCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGR 753
P P+ G GC +G + P D R + TC+ TCG
Sbjct: 2431 GPHETCRPSGGSL-----GCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGT 2485
Query: 754 RP 755
RP
Sbjct: 2486 RP 2487
Score = 50.8 bits (120), Expect = 1e-05
Identities = 57/229 (24%), Positives = 85/229 (37%), Gaps = 21/229 (9%)
Query: 1073 GSCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDK 1130
G C PV C H GR + C+ CSC + + + CQ+ C P K
Sbjct: 5166 GVCIPVQDC---GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVK 5222
Query: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH-- 1188
A A + C C+ + TFDG Y L+ C ++
Sbjct: 5223 AEARN-------CWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWY 5275
Query: 1189 --VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELR-- 1244
V +V + D V L + V V+G V LP E L V +
Sbjct: 5276 RVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP--AEKLASVSVSRT 5333
Query: 1245 -GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDD 1292
++++ + G+QV +V V V + G+ CG CGNF+G +D
Sbjct: 5334 PDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382
Score = 50.1 bits (118), Expect = 2e-05
Identities = 77/297 (25%), Positives = 93/297 (31%), Gaps = 70/297 (23%)
Query: 579 CVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQ 638
CV PCP P C P+ QE F P D C DG
Sbjct: 2243 CVSKPCPSP------CTPE----------------QQESFGGP-DACGVISATDG----- 2274
Query: 639 RLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKA 698
P APC H P GCL + P A ++ C
Sbjct: 2275 ----PLAPC-HGLVPPA-QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWR 2328
Query: 699 CAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNL-----CTCLGGFVTCGR 753
P CPF CP E G+S + E C C C GFV G
Sbjct: 2329 -RPDFCPFQ-----CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG- 2381
Query: 754 RPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGS-MRC 811
+P G C GC + G+T P C SLC C+EG + C
Sbjct: 2382 ---------DTCVPVGQC-----GCLHDDRYYPLGQTFYP--GPGCDSLCRCREGGEVSC 2425
Query: 812 QKKPCPPALCPHPSPGPCFCPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
+ C P PS G C S C + G H DG F+ G+C + Q
Sbjct: 2426 EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 2481
Score = 50.1 bits (118), Expect = 2e-05
Identities = 77/297 (25%), Positives = 93/297 (31%), Gaps = 70/297 (23%)
Query: 579 CVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQ 638
CV PCP P C P+ QE F P D C DG
Sbjct: 3444 CVSKPCPSP------CTPE----------------QQESFGGP-DACGVISATDG----- 3475
Query: 639 RLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKA 698
P APC H P GCL + P A ++ C
Sbjct: 3476 ----PLAPC-HGLVPPA-QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWR 3529
Query: 699 CAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNL-----CTCLGGFVTCGR 753
P CPF CP E G+S + E C C C GFV G
Sbjct: 3530 -RPDFCPFQ-----CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG- 3582
Query: 754 RPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGS-MRC 811
+P G C GC + G+T P C SLC C+EG + C
Sbjct: 3583 ---------DTCVPVGQC-----GCLHDDRYYPLGQTFYP--GPGCDSLCRCREGGEVSC 3626
Query: 812 QKKPCPPALCPHPSPGPCFCPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
+ C P PS G C S C + G H DG F+ G+C + Q
Sbjct: 3627 EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDF-MGTCVYVLAQ 3682
Score = 48.9 bits (115), Expect = 4e-05
Identities = 79/302 (26%), Positives = 102/302 (33%), Gaps = 72/302 (23%)
Query: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 3440 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 3484
Query: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
P C A + +P G P+ + C + Q R P CP
Sbjct: 3485 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLREWRRPDFCPFQCPAH 3541
Query: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
L G+ CP CP AP GC CR C+C G V
Sbjct: 3542 SHYELCGDSCPGSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 3584
Query: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKAC 699
P C GCL+ + + G+ F LC C EG VSCEP +C
Sbjct: 3585 CVPVGQC-------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 3631
Query: 700 APALCPFPARGDCCPDCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGR 753
P P+ G GC +G + P D + TC+ TCG
Sbjct: 3632 GPHETCRPSGGSL-----GCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGT 3686
Query: 754 RP 755
RP
Sbjct: 3687 RP 3688
Score = 47.4 bits (111), Expect = 1e-04
Identities = 49/191 (25%), Positives = 66/191 (34%), Gaps = 56/191 (29%)
Query: 299 IPGQCCPVCDG-------CEYQG---HQYQSQETFRLQERGLC-VRCSCQAGEVSCEEQE 347
+PGQ P+CD C+ G H ++S+E LC + C + +C
Sbjct: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--------LCPLSCPPHSHYEACS-YG 1148
Query: 348 CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAP 407
CP++ LP G C G E EG CVC +G G P A
Sbjct: 1149 CPLSCGDLPVPG-----GC---GSECHEG------------CVCDEGFALSGESCLPLAS 1188
Query: 408 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQD-GTVTCSLVDCPPTT 466
C C + + GQ F CHCQ+ G V+C C P
Sbjct: 1189 C---------------GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHE 1233
Query: 467 CARPQSGPGQC 477
+P G C
Sbjct: 1234 ACQPSGGSLGC 1244
Score = 47.4 bits (111), Expect = 1e-04
Identities = 60/242 (24%), Positives = 87/242 (35%), Gaps = 28/242 (11%)
Query: 641 PCPPAPCAHPRQGPCCPSCDGC------LYQGKEFASGERFPS-PTAACHLCLCWEGSVS 693
PC P P P C PS D C YQ +EF P+ P ++CH + +G +
Sbjct: 3829 PCLPPPTCPPGSAGCIPS-DKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLK 3887
Query: 694 ------CEPKACAPALCP-FPARGDCCPDCDGC--EYLGESYL-----SNQEFPDPREPC 739
C LC A C G + E++ N + + C
Sbjct: 3888 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTC 3947
Query: 740 NL-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHGVTTASGETLPDPLD 796
+L C+ L + C E C + +G C Q GC ++GV +T+ +D
Sbjct: 3948 SLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVL--ID 4005
Query: 797 PTCSLCTCQEGSMR-CQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAG 855
CTC G + CQ+ C P PS G C C Q+ + +G G
Sbjct: 4006 NCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065
Query: 856 SC 857
C
Sbjct: 4066 VC 4067
Score = 46.6 bits (109), Expect = 2e-04
Identities = 65/258 (25%), Positives = 83/258 (32%), Gaps = 53/258 (20%)
Query: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
+G C KPCP P GP C V CH + + Q D
Sbjct: 2238 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2297
Query: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ +G P G C V+ C +L+ R CP C AH G
Sbjct: 2298 QVQGHPGGLCP-------AVATYVAACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGD 2348
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
+C S EG + R C+ G C P QC C H+ R Y G+
Sbjct: 2349 SC---PGSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDDRYYPLGQ 2403
Query: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSN 1025
+F PG +C C E V C PS GP C +L
Sbjct: 2404 TFYPGPGCDSLCRCREGGE---------------VSCEPSSC---GPHETCRPSGGSLGC 2445
Query: 1026 CSEGLLGSELAPPDPCYT 1043
+ G + A DP YT
Sbjct: 2446 VAVGSTTCQ-ASGDPHYT 2462
Score = 46.6 bits (109), Expect = 2e-04
Identities = 65/258 (25%), Positives = 83/258 (32%), Gaps = 53/258 (20%)
Query: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
+G C KPCP P GP C V CH + + Q D
Sbjct: 3439 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 3498
Query: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ +G P G C V+ C +L+ R CP C AH G
Sbjct: 3499 QVQGHPGGLCP-------AVATYVAACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGD 3549
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
+C S EG + R C+ G C P QC C H+ R Y G+
Sbjct: 3550 SC---PGSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDDRYYPLGQ 3604
Query: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSN 1025
+F PG +C C E V C PS GP C +L
Sbjct: 3605 TFYPGPGCDSLCRCREGGE---------------VSCEPSSC---GPHETCRPSGGSLGC 3646
Query: 1026 CSEGLLGSELAPPDPCYT 1043
+ G + A DP YT
Sbjct: 3647 VAVGSTTCQ-ASGDPHYT 3663
Score = 46.6 bits (109), Expect = 2e-04
Identities = 67/243 (27%), Positives = 82/243 (33%), Gaps = 46/243 (18%)
Query: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
+G C KPCP P GP C V CH + + Q D
Sbjct: 4640 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 4699
Query: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ +G P G C V+ C +L R CP C AH G
Sbjct: 4700 QVQGHPGGLCP-------AVATYVAACQAAGAQLGEWRRPDFCPL--QCPAHSHYELCGD 4750
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
+C S EG + R C+ G C P QC C H+GR Y GE
Sbjct: 4751 SC---PVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDGRYYPLGE 4805
Query: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQ--LLPPGPQHCCPT-CAEA 1022
F PG + CE CE P G + C C P + L G Q C T C
Sbjct: 4806 VFYPGPE-CE-RRCECGPGGHVT-------CQEGAACGPHEECRLEDGVQACHATGCGRC 4856
Query: 1023 LSN 1025
L+N
Sbjct: 4857 LAN 4859
Score = 45.8 bits (107), Expect = 3e-04
Identities = 62/256 (24%), Positives = 88/256 (34%), Gaps = 55/256 (21%)
Query: 643 PPAPCAHPRQGPCCPSCDGCL------------YQGKEFASGERFPS-PTAACHLC---- 685
P +PC P PC P + C+ YQ +EF P+ P ++CH
Sbjct: 1424 PDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 1481
Query: 686 ---------LCWEG---SVSCEP-----KACAPA---LCPFPARGDCCPDCDGCEYLGES 725
LC G S+ C AC A + P+ C +C
Sbjct: 1482 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP-------- 1533
Query: 726 YLSNQEFPDPREPCNL-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHG 782
N + + C+L C+ L C E C + +G C Q GC ++G
Sbjct: 1534 --PNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
Query: 783 VTTASGETLPDPLDPTCSLCTCQEGS-MRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQG 841
V +T+ +D CTC G M CQ+ C P PS G C C
Sbjct: 1592 VYYEPEQTVL--IDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVT 1649
Query: 842 REHQDGEEFEGPAGSC 857
Q+ + +G G C
Sbjct: 1650 CRPQETCKEQGGQGVC 1665
Score = 43.1 bits (100), Expect = 0.002
Identities = 63/256 (24%), Positives = 75/256 (29%), Gaps = 71/256 (27%)
Query: 238 ARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPG 297
++P P C P E G D C +G P PC H
Sbjct: 2245 SKPCPSPCTP------------EQQESFGGPDACGVISATDG---------PLAPC-HGL 2282
Query: 298 KIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGLCVR-----CSCQAGEVSCEEQECP- 349
P Q C D C+ QGH GLC +CQA E P
Sbjct: 2283 VPPAQYFQGCLLDACQVQGHP-----------GGLCPAVATYVAACQAAGAQLREWRRPD 2331
Query: 350 VTPCALPA-SGRQLC-PAC-----ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVL 402
P PA S +LC +C L E E E CVC G G
Sbjct: 2332 FCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE-------GCVCDAGFVLSGDTC 2384
Query: 403 CPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDG-TVTCSLVD 461
P C C + + Y GQ F C C++G V+C
Sbjct: 2385 VPVGQC---------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS 2429
Query: 462 CPPTTCARPQSGPGQC 477
C P RP G C
Sbjct: 2430 CGPHETCRPSGGSLGC 2445
Score = 43.1 bits (100), Expect = 0.002
Identities = 63/256 (24%), Positives = 75/256 (29%), Gaps = 71/256 (27%)
Query: 238 ARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPG 297
++P P C P E G D C +G P PC H
Sbjct: 3446 SKPCPSPCTP------------EQQESFGGPDACGVISATDG---------PLAPC-HGL 3483
Query: 298 KIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGLCVR-----CSCQAGEVSCEEQECP- 349
P Q C D C+ QGH GLC +CQA E P
Sbjct: 3484 VPPAQYFQGCLLDACQVQGHP-----------GGLCPAVATYVAACQAAGAQLREWRRPD 3532
Query: 350 VTPCALPA-SGRQLC-PAC-----ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVL 402
P PA S +LC +C L E E E CVC G G
Sbjct: 3533 FCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE-------GCVCDAGFVLSGDTC 3585
Query: 403 CPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDG-TVTCSLVD 461
P C C + + Y GQ F C C++G V+C
Sbjct: 3586 VPVGQC---------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS 3630
Query: 462 CPPTTCARPQSGPGQC 477
C P RP G C
Sbjct: 3631 CGPHETCRPSGGSLGC 3646
Score = 42.7 bits (99), Expect = 0.003
Identities = 60/218 (27%), Positives = 75/218 (34%), Gaps = 45/218 (20%)
Query: 660 DGCLYQGKEFASGERFPSPTAACHLCLC----WEGSVSCEPKACAPALCPFPARGDCCPD 715
D CL G+ + + AAC W C P CP + + C
Sbjct: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC------PLSCPPHSHYEACSY 1147
Query: 716 CDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCC--- 772
GC LS + P P GG CG E C SG C
Sbjct: 1148 --GCP------LSCGDLPVP----------GG---CGSECHEGCVCDEGFALSGESCLPL 1186
Query: 773 PTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGSM-RCQKKPCPPALCPHPSPGPCF 830
+C GC + G G+T P C SLC CQEG + C+ C P PS G
Sbjct: 1187 ASC-GCVHQGTYHPPGQTFYP--GPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
Query: 831 CPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
C S C + G H DG F+ G+C + Q
Sbjct: 1244 CVAVGSSTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 1280
Score = 42.7 bits (99), Expect = 0.003
Identities = 59/241 (24%), Positives = 86/241 (35%), Gaps = 26/241 (10%)
Query: 641 PCPPAPCAHPRQGPCCPS--CDGCL---YQGKEFASGERFPS-PTAACHLCLCWEGSVS- 693
PC P P P C PS C L YQ +EF P+ P ++CH + +G +
Sbjct: 2628 PCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 2687
Query: 694 -----CEPKACAPALCP-FPARGDCCPDCDGC--EYLGESYL-----SNQEFPDPREPCN 740
C LC A C G + E++ N + + C+
Sbjct: 2688 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCS 2747
Query: 741 L-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHGVTTASGETLPDPLDP 797
L C+ L + C E C + +G C Q GC ++G +T+ +D
Sbjct: 2748 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVL--IDN 2805
Query: 798 TCSLCTCQEGSMR-CQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGS 856
CTC G + CQ+ C P PS G C C Q+ + +G G
Sbjct: 2806 CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGV 2865
Query: 857 C 857
C
Sbjct: 2866 C 2866
Score = 42.4 bits (98), Expect = 0.003
Identities = 70/267 (26%), Positives = 86/267 (32%), Gaps = 61/267 (22%)
Query: 122 GAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQ-CQG---PSCSELN 177
GA CG P C+ Q G PDAC G + C G P+
Sbjct: 2236 GAQGCGECVSKPCPSPCTPEQQESFGG----PDACGVISATDGPLAPCHGLVPPAQYFQG 2291
Query: 178 CL-ESCTP---PGECCPICCTEGGSHWEHG---QEWTTPGDPCRICRCLEGHIQCRQREC 230
CL ++C PG CP T + G +EW P D C H + C
Sbjct: 2292 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSC 2350
Query: 231 ASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPP 290
CP + P +GC RE C C G V C P
Sbjct: 2351 PGSCPSLSAP---------EGCESACREG--------------CVCDAGFVLSGDT-CVP 2386
Query: 291 VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSC-QAGEVSCEEQECP 349
V GQC GC + Y +TF G C C + GEVSCE C
Sbjct: 2387 V---------GQC-----GCLHDDRYYPLGQTF-YPGPGCDSLCRCREGGEVSCEPSSCG 2431
Query: 350 VTPCALPASGRQLCPA-----CELDGE 371
P+ G C A C+ G+
Sbjct: 2432 PHETCRPSGGSLGCVAVGSTTCQASGD 2458
Score = 42.4 bits (98), Expect = 0.003
Identities = 70/267 (26%), Positives = 86/267 (32%), Gaps = 61/267 (22%)
Query: 122 GAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQ-CQG---PSCSELN 177
GA CG P C+ Q G PDAC G + C G P+
Sbjct: 3437 GAQGCGECVSKPCPSPCTPEQQESFGG----PDACGVISATDGPLAPCHGLVPPAQYFQG 3492
Query: 178 CL-ESCTP---PGECCPICCTEGGSHWEHG---QEWTTPGDPCRICRCLEGHIQCRQREC 230
CL ++C PG CP T + G +EW P D C H + C
Sbjct: 3493 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSC 3551
Query: 231 ASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPP 290
CP + P +GC RE C C G V C P
Sbjct: 3552 PGSCPSLSAP---------EGCESACREG--------------CVCDAGFVLSGDT-CVP 3587
Query: 291 VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSC-QAGEVSCEEQECP 349
V GQC GC + Y +TF G C C + GEVSCE C
Sbjct: 3588 V---------GQC-----GCLHDDRYYPLGQTF-YPGPGCDSLCRCREGGEVSCEPSSCG 3632
Query: 350 VTPCALPASGRQLCPA-----CELDGE 371
P+ G C A C+ G+
Sbjct: 3633 PHETCRPSGGSLGCVAVGSTTCQASGD 3659
Score = 42.4 bits (98), Expect = 0.003
Identities = 68/257 (26%), Positives = 87/257 (33%), Gaps = 52/257 (20%)
Query: 659 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
C C + + + FP+ T A + + W GS AP P C +C G
Sbjct: 4214 CGLCGNMDRNPNNDQVFPNGTLAPSIPI-WGGSWR------APGWDPL-----CWDECRG 4261
Query: 719 -CEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPP-----GCSHPL-IPSGHC 771
C E L E P P + T G F TC PP GC + + G
Sbjct: 4262 SCPTCPEDRLEQYEGPGFCGPLSSGTG-GPFTTCHAHV--PPESFFKGCVLDVCMGGGDR 4318
Query: 772 CPTCQG-CRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP---- 826
C+ Y A+G + D TC E S P PA CP P+P
Sbjct: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378
Query: 827 ----GPCF---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQA 864
GPC C ++ C + G H+ G EF +WCRC
Sbjct: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 4438
Query: 865 GQVSCVRLQCPPLPCKL 881
G S V C P C L
Sbjct: 4439 GGGSLV---CTPASCGL 4452
Score = 41.2 bits (95), Expect = 0.008
Identities = 36/128 (28%), Positives = 44/128 (34%), Gaps = 29/128 (22%)
Query: 780 YHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--------GPCF- 830
Y A+G + D TC E S P PA CP P+P GPC
Sbjct: 3127 YVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVE 3186
Query: 831 --------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
C ++ C + G H+ G EF +WCRC G S V
Sbjct: 3187 GCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV--- 3243
Query: 874 CPPLPCKL 881
C P C L
Sbjct: 3244 CTPASCGL 3251
Score = 41.2 bits (95), Expect = 0.008
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 3150 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 3199
Query: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 3200 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 3245
Query: 285 PLPC 288
P C
Sbjct: 3246 PASC 3249
Score = 41.2 bits (95), Expect = 0.008
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 4351 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 4400
Query: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 4401 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 4446
Query: 285 PLPC 288
P C
Sbjct: 4447 PASC 4450
Score = 40.8 bits (94), Expect = 0.010
Identities = 37/129 (28%), Positives = 45/129 (34%), Gaps = 31/129 (24%)
Query: 780 YHGVTTASGETLPDPLDPTCSLCTCQEGS-MRCQKKPCPPALCPHPSP--------GPCF 830
Y A+G + D TC E S PCP A CP P+P GPC
Sbjct: 1926 YVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCP-ASCPSPAPLTTPAVCEGPCV 1984
Query: 831 ---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRL 872
C ++ C + G H+ G EF +WCRC G S V
Sbjct: 1985 EGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV-- 2042
Query: 873 QCPPLPCKL 881
C P C L
Sbjct: 2043 -CTPASCGL 2050
Score = 40.0 bits (92), Expect = 0.017
Identities = 65/256 (25%), Positives = 77/256 (30%), Gaps = 71/256 (27%)
Query: 704 CPFPARGDCCPDCDGCEYLGESYLSNQE---FPDPREPCNLCTCL----GGFVTCGRRPC 756
C GDC P D + + S E DP+ P C G C C
Sbjct: 1040 CGATEPGDC-PKLDSL--VAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
Query: 757 EPPGCSHPLIPSGHCCPTCQGCRYHGVTT---ASGETLPDPLDPTCSLCTCQEGSMRCQK 813
PG S PL + C+ G T S E P P C G
Sbjct: 1097 LLPGQSGPLCDA--LATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYG------ 1148
Query: 814 KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
CP + P PG C CH E C C G +
Sbjct: 1149 --CPLSCGDLPVPGGCGSE-CH----------------------EGCVCDEG-FALSGES 1182
Query: 874 CPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHE-GVVTCARIQ 932
C PL SC GC+ G HP G + P S C C E G+V+C
Sbjct: 1183 CLPL---------ASC-----GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSS 1228
Query: 933 CISSCAQPRQGPHDCC 948
C GPH+ C
Sbjct: 1229 C---------GPHEAC 1235
Score = 38.1 bits (87), Expect = 0.065
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 15/97 (15%)
Query: 910 VPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCS-DCEHEGRKYEPGESFQ 968
+P C S CHEG V C +S C P S C H+G + PG++F
Sbjct: 1156 LPVPGGCGS-ECHEGCV-CDEGFALSG--------ESCLPLASCGCVHQGTYHPPGQTFY 1205
Query: 969 PGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005
PG +C C+ EG + C C C PS
Sbjct: 1206 PGPGCDSLCHCQ---EG-GLVSCESSSCGPHEACQPS 1238
Score = 38.1 bits (87), Expect = 0.065
Identities = 37/124 (29%), Positives = 45/124 (36%), Gaps = 31/124 (25%)
Query: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
+C E + E C P CP C TTP PC C+C G +
Sbjct: 1949 TCPENSHYEVCGSP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 1998
Query: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 1999 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 2044
Query: 285 PLPC 288
P C
Sbjct: 2045 PASC 2048
Score = 37.7 bits (86), Expect = 0.084
Identities = 65/243 (26%), Positives = 82/243 (33%), Gaps = 62/243 (25%)
Query: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 4641 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 4685
Query: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
P C A + +P G P+ + C + Q R PL CP
Sbjct: 4686 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLGEWRRPDFCPLQCPAH 4742
Query: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
L G+ CP CP AP GC CR C+C G V
Sbjct: 4743 SHYELCGDSCPVSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 4785
Query: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSC-EPKA 698
P C GCL+ G+ + GE F C C G V+C E A
Sbjct: 4786 CVPVGQC-------------GCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 4832
Query: 699 CAP 701
C P
Sbjct: 4833 CGP 4835
Score = 37.0 bits (84), Expect = 0.14
Identities = 57/200 (28%), Positives = 70/200 (35%), Gaps = 50/200 (25%)
Query: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------CFLNG---RE 258
P P R C H + + C Y LPG P+CD C G
Sbjct: 1071 PKGPFREC-----HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1125
Query: 259 HRSGE--PVGSGDPCSHCR-CANGSVQCEPLPCPPVPCRHPGKIPGQCCP--VCD----- 308
RS E P+ S P SH C+ G PL C +P PG +C VCD
Sbjct: 1126 WRSEELCPL-SCPPHSHYEACSYGC----PLSCGDLPV--PGGCGSECHEGCVCDEGFAL 1178
Query: 309 -----------GCEYQGHQYQSQETFRLQERGLCVRCSCQAGE-VSCEEQECPVTPCALP 356
GC +QG + +TF G C CQ G VSCE C P
Sbjct: 1179 SGESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
Query: 357 ASGRQLCPA-----CELDGE 371
+ G C A C+ G+
Sbjct: 1238 SGGSLGCVAVGSSTCQASGD 1257
Score = 36.2 bits (82), Expect = 0.25
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 104 PEGARWEPDACT-ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETF--SPDACTTCR 160
PEG AC CVC G G GC +G+ Y GE F P+ C
Sbjct: 4762 PEGCE---SACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
Query: 161 CLTGA-VQCQ-----GP--SCSELNCLESCTPPGECCPICCTEGGSHW 200
C G V CQ GP C + +++C G C C GG H+
Sbjct: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATG--CGRCLANGGIHY 4864
Score = 35.8 bits (81), Expect = 0.32
Identities = 118/496 (23%), Positives = 154/496 (31%), Gaps = 95/496 (19%)
Query: 117 CVCQDG----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTT--CRCLTGAVQCQG 170
C C G A C P L + GC NG + G F D + CRC G
Sbjct: 4389 CQCDAGFVLSADRCVP---LNNGCGCWANGTYHEAGSEFWADGTCSQWCRC--------G 4437
Query: 171 PSCSELNCLESCTPPGECCPICCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
P L C + GE C + + + G E GDP + L+GH Q
Sbjct: 4438 PGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT--LDGHRFDFQGT 4495
Query: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
C L P P + EHR + V S+ R + L
Sbjct: 4496 CEYLLSAPCHGPP---LGAENFTVTVANEHRGSQAV------SYTRSVTLQIYNHSLT-- 4544
Query: 290 PVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECP 349
+ R P K+ DG + +Q G V + +G + +
Sbjct: 4545 -LSARWPRKLQ------VDGV-FVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 4596
Query: 350 V---TPCALPASGRQLCPACELDGEEFAEGVQWEPDG------RPCTACVCQD------- 393
V P A AS LC D + + V +P G + C CV +
Sbjct: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP 4656
Query: 394 -------GVPKCGAVLC---PPAPCQHPTQPPGACCPSC--DSCTYHSQVYANGQNFTDA 441
G CG + P APC H PP C D+C
Sbjct: 4657 EQQESFGGPDACGVISATDGPLAPC-HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
Query: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPR 501
+ C A Q G RP P QC + + V S S P
Sbjct: 4716 VAACQAAGAQLGE------------WRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP- 4762
Query: 502 DPCQECRCQEGHAHCQPRPCPRAPCAHPLPG-TCCPNDCSGCAFGGKEYPSGADFPHPSD 560
+ C E C+EG L G TC P GC G+ YP G F +P
Sbjct: 4763 EGC-ESACREGCV---------CDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF-YPGP 4811
Query: 561 PC-RLCRC-LSGNVQC 574
C R C C G+V C
Sbjct: 4812 ECERRCECGPGGHVTC 4827
Score = 35.4 bits (80), Expect = 0.42
Identities = 62/239 (25%), Positives = 79/239 (33%), Gaps = 53/239 (22%)
Query: 374 AEGVQWEPDGRPCTACVCQDGVPK--------------CGAVLCPPAP---CQHPTQPPG 416
A G W+ + RP PK CG + P P C P G
Sbjct: 1027 AFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQG 1086
Query: 417 ACCPSCDSCTYHSQVYANGQNFTDADS-PCHACHCQDGTVTCS---LVDCPPTTCARPQS 472
A C Y + GQ+ D+ +A CQ T + P +C P S
Sbjct: 1087 AV----RDCVY-DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP-PHS 1140
Query: 473 GPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE-CRCQEGHAHCQPRPCPRAPCAHPLP 531
C CP + ++ V G S C E C C EG A L
Sbjct: 1141 HYEACSYGCP--LSCGDLPVPGGCGSE----CHEGCVCDEGFA---------------LS 1179
Query: 532 G-TCCPNDCSGCAFGGKEYPSGADFPHPSDPC-RLCRCLSGN-VQCLARRCVPLPCPEP 587
G +C P GC G +P G F +P C LC C G V C + C P +P
Sbjct: 1180 GESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
Score = 34.7 bits (78), Expect = 0.71
Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 35/152 (23%)
Query: 564 LCRCLSGNVQCLARRCVPL-----PCPEPVLLPGE-----CCPQCPAPAGCPRPGAAHAR 613
LCR LS Q + + P P+ P C P CP GAA
Sbjct: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCN----GAAAPS 769
Query: 614 HQEYFSPPGDPC-RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASG 672
+ G PC C+CL G V+ P + C GC +QG + A G
Sbjct: 770 NCS-----GRPCVEGCVCLPGFVASGGACVPASSC-------------GCTFQGLQLAPG 811
Query: 673 ERFPSPTAACHLCLCWEGS--VSCEPKACAPA 702
+ + C C + V+C K PA
Sbjct: 812 QEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
Score = 33.9 bits (76), Expect = 1.2
Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 42/184 (22%)
Query: 688 WEGSVSCEPKACAPALCPFPARGDCCP-DCDGCEYLGESYLSNQEFPDPREPC-NLCTCL 745
W +C P +C PA + G CP C+G S S + PC C CL
Sbjct: 735 WRSPANC-PLSC-PANSRYELCGPACPTSCNGAA--APSNCSGR-------PCVEGCVCL 783
Query: 746 GGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS-LCT 803
GFV G G C P GC + G+ A G+ + D C CT
Sbjct: 784 PGFVASG----------------GACVPASSCGCTFQGLQLAPGQEV--WADELCQRRCT 825
Query: 804 CQEGS--MRCQ-KKPCPPALCPHPSPG--PCFCPVCHSCLSQGREHQ---DGEEFEGPAG 855
C + + C+ K+ CP G C+ +C G H DG F+ G
Sbjct: 826 CNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF-MG 884
Query: 856 SCEW 859
+C +
Sbjct: 885 TCTY 888
Score = 33.5 bits (75), Expect = 1.6
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 1964 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 2021
Query: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
+ G + CRC G + C C
Sbjct: 2022 FWADGTCSQWCRCGPGGGSLVCTPASC 2048
Score = 33.5 bits (75), Expect = 1.6
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 3165 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 3222
Query: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
+ G + CRC G + C C
Sbjct: 3223 FWADGTCSQWCRCGPGGGSLVCTPASC 3249
Score = 33.5 bits (75), Expect = 1.6
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 4366 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 4423
Query: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
+ G + CRC G + C C
Sbjct: 4424 FWADGTCSQWCRCGPGGGSLVCTPASC 4450
Score = 31.6 bits (70), Expect = 6.0
Identities = 51/225 (22%), Positives = 66/225 (29%), Gaps = 36/225 (16%)
Query: 287 PC-PPVPCRHPGK---IPGQCCPVCDGCEYQGHQY---QSQETFRLQERGL--------- 330
PC PP PC PG IP CP +YQ ++ S T L
Sbjct: 1427 PCLPPTPCP-PGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLK 1485
Query: 331 -CVRCSCQAG---EVSCEEQECPVTPCAL------PASGRQLCPACELDGEEFAEGVQWE 380
C+ C G + C V+ C P CP E +E
Sbjct: 1486 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM------ECPPNSHYE 1539
Query: 381 PDGRPCT-ACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSC-TYHSQVYANGQNF 438
C+ C P+C C G C C YH+ VY +
Sbjct: 1540 LCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQT 1599
Query: 439 TDADSPCHACHCQDGT-VTCSLVDCPPTTCARPQSGPGQCCPRCP 482
D+ C C G + C C P +P G C + P
Sbjct: 1600 VLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDP 1644
Score = 31.6 bits (70), Expect = 6.0
Identities = 59/257 (22%), Positives = 74/257 (28%), Gaps = 59/257 (22%)
Query: 755 PCEPPGCSHP----LIPSGHCCPTC----QGCRYHGVTTA------SGETLPDPLDPT-- 798
PC PP P IPS C P Q + G+ ++ S L DP P
Sbjct: 2628 PCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 2687
Query: 799 CSLCTCQEG---SMRCQKKPCPPALCP------HPSPGPCFCPVCHSCLSQGREHQDGEE 849
C C G S+ C + C P FCP+ E
Sbjct: 2688 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPM---------ECPQNSH 2738
Query: 850 FEGPAGSCEW-CRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGC-LAHGEEHPEGS 907
+E A +C C + + C C G C + C H + E
Sbjct: 2739 YELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPE 2798
Query: 908 RWVPPDSACSSCVCHEG-VVTCARIQC-ISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGE 965
+ V D+ C CH G VV C C QP G C
Sbjct: 2799 QTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCV----------------- 2841
Query: 966 SFQPGADPCEVCICEPQ 982
DPC C PQ
Sbjct: 2842 ----NKDPCHGVTCRPQ 2854
Score = 31.6 bits (70), Expect = 6.0
Identities = 59/257 (22%), Positives = 75/257 (29%), Gaps = 59/257 (22%)
Query: 755 PCEPPGCSHP----LIPSGHCCPTC----QGCRYHGVTTA------SGETLPDPLDPT-- 798
PC PP P IPS C P Q + G+ ++ S L DP P
Sbjct: 3829 PCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888
Query: 799 CSLCTCQEG---SMRCQKKPCPPALCP------HPSPGPCFCPVCHSCLSQGREHQDGEE 849
C C G S+ C + C P FCP+ E
Sbjct: 3889 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPM---------ECPQNSH 3939
Query: 850 FEGPAGSCEW-CRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGC-LAHGEEHPEGS 907
+E A +C C + + C C G C + C H + E
Sbjct: 3940 YELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPE 3999
Query: 908 RWVPPDSACSSCVCHEG-VVTCARIQC-ISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGE 965
+ V D+ C CH G VV C C QP G C +
Sbjct: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTK--------------- 4044
Query: 966 SFQPGADPCEVCICEPQ 982
DPC C PQ
Sbjct: 4045 ------DPCHGVTCRPQ 4055
Score = 31.6 bits (70), Expect = 6.0
Identities = 19/67 (28%), Positives = 24/67 (35%), Gaps = 1/67 (1%)
Query: 417 ACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDG-TVTCSLVDCPPTTCARPQSGPG 475
AC P YH+ VY + D+ C C G V C C P +P G
Sbjct: 3980 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGIL 4039
Query: 476 QCCPRCP 482
C + P
Sbjct: 4040 SCVTKDP 4046
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 208 bits (529), Expect = 4e-53
Identities = 184/560 (32%), Positives = 237/560 (42%), Gaps = 85/560 (15%)
Query: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 657 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 711
Query: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
A ++ C + G E PD C C LC +CP +SCP + P C
Sbjct: 712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC-GDSCP-VSCPSL---SAPEGCE 766
Query: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCM-------AGTV-----RCQSQ-R 1120
CR + CV V SG DTC C C+ G V C+ +
Sbjct: 767 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
Query: 1121 CSP---------LSCGPDKAPALSPG--SC----CPRCLPRPASCMAFGDPHYRTFDGRL 1165
C P +CGP + L G +C C RCL A G HY T DGR+
Sbjct: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCL-------ANGGIHYITLDGRV 871
Query: 1166 LHFQGSCSYVLAKDCH----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGA 1221
GSCSYVLA+ CH DFS+ + + G Q + V + V L Q
Sbjct: 872 YDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQQ 926
Query: 1222 VTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
VTVDG VALP + + V G ++L GL++L+DG + + +S+P ++GR CGL
Sbjct: 927 VTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 985
Query: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
CGNFNG DD P G S FG +W+V G G G + P A A
Sbjct: 986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWRV-PGSSKGCGEGCGPQGCPVCLAEETAPY 1044
Query: 1342 EANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHC 1399
E+N CG L++ PF+ C AV+ P +F CVYDLCA A LC +L AY + C
Sbjct: 1045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLAAYTAAC 1101
Query: 1400 RQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPG 1458
+ AGV WR + C + CP + C RTC L L C C G
Sbjct: 1102 QAAGVAVKPWRTDSFCPLHCPAHSHYSI------CTRTCQGSCAALSGLTG-CTTRCFEG 1154
Query: 1459 CQCPAGLVEHEAHCIPPEAC 1478
C+C + + CIP + C
Sbjct: 1155 CECDDRFLLSQGVCIPVQDC 1174
Score = 195 bits (495), Expect = 3e-49
Identities = 132/369 (35%), Positives = 174/369 (47%), Gaps = 26/369 (7%)
Query: 1121 CSPLSCGPDKAPALSPGSCCPRCLPR-PASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKD 1179
C ++C P + G CLP A+C +GDPHY +FDGR FQG+C+YVLA
Sbjct: 47 CHGVTCRPQETCKEQGGQGV--CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATT 104
Query: 1180 CHSG-------DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD--GAVTVDGHPVA 1230
G F+V N++RG V++ + V V + + +D G V V+G A
Sbjct: 105 GCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTA 164
Query: 1231 LPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFA 1289
LP + + + V +L A GLQV +D +V+V++P SY G CGLCGN +
Sbjct: 165 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 224
Query: 1290 QDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGV 1349
+D P G L PS +G SW+ W R P + E CG
Sbjct: 225 NNDQVFPNGTLAPSIPIWGGSWRAPG--WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGP 282
Query: 1350 L---KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT- 1405
L PF+ CHA VPPE FF CV D+C G LC AL +Y + C+ AGV
Sbjct: 283 LAPGTGGPFTTCHAHVPPESFFKGCVLDVCM---GGGDHDILCKALASYVAACQAAGVVI 339
Query: 1406 PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGL 1465
WR C + CP ++ CGPPCP +C PL A C PCV GCQC AG
Sbjct: 340 EDWRAQVGCEITCP--ENSHYEVCGPPCPASC-PSPAPL-TTPAVCEGPCVEGCQCDAGF 395
Query: 1466 VEHEAHCIP 1474
V C+P
Sbjct: 396 VLSADRCVP 404
Score = 194 bits (494), Expect = 4e-49
Identities = 169/577 (29%), Positives = 235/577 (40%), Gaps = 86/577 (14%)
Query: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
+C C C + + G F C P G P CH P G
Sbjct: 258 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLAPGTGGPFTTCHAHVPPESFFKG 306
Query: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
C + G C A ++ C + G++ + C ++ + CP
Sbjct: 307 CVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 366
Query: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
SCP T P G C C+ + R V A E W
Sbjct: 367 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 425
Query: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 426 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 481
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 541
Query: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
++ L + VDG VALPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 542 SLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 601
Query: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
P +Y CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 602 PAAYAASLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 652
Query: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 653 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 707
Query: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
LC A+ Y + C+ AG WR P C + CP ++ CG CP +C +
Sbjct: 708 -----LCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSH--YELCGDSCPVSCPSLS 760
Query: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
P G C C GC C AG V C+P C
Sbjct: 761 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 792
Score = 50.8 bits (120), Expect = 1e-05
Identities = 57/229 (24%), Positives = 85/229 (37%), Gaps = 21/229 (9%)
Query: 1073 GSCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDK 1130
G C PV C H GR + C+ CSC + + + CQ+ C P K
Sbjct: 1166 GVCIPVQDC---GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVK 1222
Query: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH-- 1188
A A + C C+ + TFDG Y L+ C ++
Sbjct: 1223 AEARN-------CWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWY 1275
Query: 1189 --VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELR-- 1244
V +V + D V L + V V+G V LP E L V +
Sbjct: 1276 RVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP--AEKLASVSVSRT 1333
Query: 1245 -GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDD 1292
++++ + G+QV +V V V + G+ CG CGNF+G +D
Sbjct: 1334 PDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382
Score = 46.6 bits (109), Expect = 2e-04
Identities = 67/243 (27%), Positives = 82/243 (33%), Gaps = 46/243 (18%)
Query: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
+G C KPCP P GP C V CH + + Q D
Sbjct: 640 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 699
Query: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ +G P G C V+ C +L R CP C AH G
Sbjct: 700 QVQGHPGGLCP-------AVATYVAACQAAGAQLGEWRRPDFCPL--QCPAHSHYELCGD 750
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
+C S EG + R C+ G C P QC C H+GR Y GE
Sbjct: 751 SC---PVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDGRYYPLGE 805
Query: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQ--LLPPGPQHCCPT-CAEA 1022
F PG + CE CE P G + C C P + L G Q C T C
Sbjct: 806 VFYPGPE-CE-RRCECGPGGHVT-------CQEGAACGPHEECRLEDGVQACHATGCGRC 856
Query: 1023 LSN 1025
L+N
Sbjct: 857 LAN 859
Score = 42.0 bits (97), Expect = 0.004
Identities = 69/258 (26%), Positives = 85/258 (32%), Gaps = 54/258 (20%)
Query: 659 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
C C + + + FP+ T A + + W GS AP P C +C G
Sbjct: 214 CGLCGNMDRNPNNDQVFPNGTLAPSIPI-WGGSWR------APGWDPL-----CWDECRG 261
Query: 719 -CEYLGESYLSNQEFPDPREPCNLCTCLGG-FVTCGRRPCEPP-----GCSHPLIPSG-- 769
C E L E P P L GG F TC PP GC + G
Sbjct: 262 SCPTCPEDRLEQYEGPGFCGP--LAPGTGGPFTTCHAHV--PPESFFKGCVLDVCMGGGD 317
Query: 770 HCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--- 826
H Y A+G + D TC E S P PA CP P+P
Sbjct: 318 HDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTT 377
Query: 827 -----GPCF---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQ 863
GPC C ++ C + G H+ G EF +WCRC
Sbjct: 378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 437
Query: 864 AGQVSCVRLQCPPLPCKL 881
G S V C P C L
Sbjct: 438 PGGGSLV---CTPASCGL 452
Score = 41.2 bits (95), Expect = 0.008
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 351 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 400
Query: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 401 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 446
Query: 285 PLPC 288
P C
Sbjct: 447 PASC 450
Score = 37.7 bits (86), Expect = 0.084
Identities = 65/243 (26%), Positives = 82/243 (33%), Gaps = 62/243 (25%)
Query: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 641 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 685
Query: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
P C A + +P G P+ + C + Q R PL CP
Sbjct: 686 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLGEWRRPDFCPLQCPAH 742
Query: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
L G+ CP CP AP GC CR C+C G V
Sbjct: 743 SHYELCGDSCPVSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 785
Query: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSC-EPKA 698
P C GCL+ G+ + GE F C C G V+C E A
Sbjct: 786 CVPVGQC-------------GCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 832
Query: 699 CAP 701
C P
Sbjct: 833 CGP 835
Score = 36.2 bits (82), Expect = 0.25
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 104 PEGARWEPDACT-ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETF--SPDACTTCR 160
PEG AC CVC G G GC +G+ Y GE F P+ C
Sbjct: 762 PEGCE---SACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
Query: 161 CLTGA-VQCQ-----GP--SCSELNCLESCTPPGECCPICCTEGGSHW 200
C G V CQ GP C + +++C G C C GG H+
Sbjct: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATG--CGRCLANGGIHY 864
Score = 35.8 bits (81), Expect = 0.32
Identities = 118/496 (23%), Positives = 154/496 (31%), Gaps = 95/496 (19%)
Query: 117 CVCQDG----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTT--CRCLTGAVQCQG 170
C C G A C P L + GC NG + G F D + CRC G
Sbjct: 389 CQCDAGFVLSADRCVP---LNNGCGCWANGTYHEAGSEFWADGTCSQWCRC--------G 437
Query: 171 PSCSELNCLESCTPPGECCPICCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
P L C + GE C + + + G E GDP + L+GH Q
Sbjct: 438 PGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT--LDGHRFDFQGT 495
Query: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
C L P P + EHR + V S+ R + L
Sbjct: 496 CEYLLSAPCHGPP---LGAENFTVTVANEHRGSQAV------SYTRSVTLQIYNHSLT-- 544
Query: 290 PVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECP 349
+ R P K+ DG + +Q G V + +G + +
Sbjct: 545 -LSARWPRKLQ------VDGV-FVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 596
Query: 350 V---TPCALPASGRQLCPACELDGEEFAEGVQWEPDG------RPCTACVCQD------- 393
V P A AS LC D + + V +P G + C CV +
Sbjct: 597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP 656
Query: 394 -------GVPKCGAVLC---PPAPCQHPTQPPGACCPSC--DSCTYHSQVYANGQNFTDA 441
G CG + P APC H PP C D+C
Sbjct: 657 EQQESFGGPDACGVISATDGPLAPC-HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
Query: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPR 501
+ C A Q G RP P QC + + V S S P
Sbjct: 716 VAACQAAGAQLGE------------WRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP- 762
Query: 502 DPCQECRCQEGHAHCQPRPCPRAPCAHPLPG-TCCPNDCSGCAFGGKEYPSGADFPHPSD 560
+ C E C+EG L G TC P GC G+ YP G F +P
Sbjct: 763 EGC-ESACREGCV---------CDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF-YPGP 811
Query: 561 PC-RLCRC-LSGNVQC 574
C R C C G+V C
Sbjct: 812 ECERRCECGPGGHVTC 827
Score = 33.5 bits (75), Expect = 1.6
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 366 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 423
Query: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
+ G + CRC G + C C
Sbjct: 424 FWADGTCSQWCRCGPGGGSLVCTPASC 450
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 208 bits (529), Expect = 4e-53
Identities = 171/519 (32%), Positives = 217/519 (41%), Gaps = 82/519 (15%)
Query: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
CP + CPP+ + C TC+ S S APP QCQD
Sbjct: 1528 CP--MECPPNSHY----ELCADTCSLGCSALS--------APP------QCQD------- 1560
Query: 1056 QACPELSCPLSERHTPPGSCCPVCRAPTQSC--VHQGREVASGERWTVDTCTS-CSCMAG 1112
C E C G C P Q C H G + +D C C+C AG
Sbjct: 1561 -GCAE-GCQCDSGFLYNGQAC----VPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG 1614
Query: 1113 T-VRCQSQRCSP----------LSC---GPDKAPALSPGSCCPR------CLPR-PASCM 1151
+ CQ C P LSC P P C CLP A+C
Sbjct: 1615 KGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCW 1674
Query: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQE 1204
+GDPHY +FDGR FQG+C+YVLA G F+V N +RG V++ +
Sbjct: 1675 LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 1734
Query: 1205 VAVLLGDMAVRLLQDGA----VTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVL 1259
V V + + +D V V+G ALP + + + V +L A GLQV
Sbjct: 1735 VTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 1794
Query: 1260 WDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWP 1319
+D +V+V++P SY G CGLCGN + +D P G L PS +G SW+ W
Sbjct: 1795 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WD 1852
Query: 1320 GRPCSAGREVDPCRAAGYRARREANARCGVLKS---SPFSRCHAVVPPEPFFAACVYDLC 1376
R P + E CG L S PF+ CHA VPPE FF CV D+C
Sbjct: 1853 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVC 1912
Query: 1377 ACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPR 1435
G LC AL +Y + C+ AGV WR C + CP ++ CGPPCP
Sbjct: 1913 M---GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGPPCPA 1967
Query: 1436 TCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIP 1474
+C PL A C PCV GCQC AG V C+P
Sbjct: 1968 SC-PSPAPL-TTPAVCEGPCVEGCQCDAGFVLSADRCVP 2004
Score = 207 bits (526), Expect = 8e-53
Identities = 183/560 (32%), Positives = 237/560 (42%), Gaps = 85/560 (15%)
Query: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 2257 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 2311
Query: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
A ++ C + G E PD C C LC +CP +SCP + P C
Sbjct: 2312 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC-GDSCP-VSCPSL---SAPEGCE 2366
Query: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCM-------AGTV-----RCQSQ-R 1120
CR + CV V SG DTC C C+ G V C+ +
Sbjct: 2367 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
Query: 1121 CSP---------LSCGPDKAPALSPG--SC----CPRCLPRPASCMAFGDPHYRTFDGRL 1165
C P +CGP + L G +C C RCL A G HY T DGR+
Sbjct: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCL-------ANGGIHYITLDGRV 2471
Query: 1166 LHFQGSCSYVLAKDCH----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGA 1221
GSCSYVLA+ CH DFS+ + + G Q + V + V L Q
Sbjct: 2472 YDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQQ 2526
Query: 1222 VTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
VTVDG VALP + + V G ++L GL++L+DG + + +S+P ++GR CGL
Sbjct: 2527 VTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 2585
Query: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
CGNFNG DD P G S FG +W+ + G G G + P A A
Sbjct: 2586 CGNFNGNWSDDFVLPNGSAASSVETFGAAWR-APGSSKGCGEGCGPQGCPVCLAEETAPY 2644
Query: 1342 EANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHC 1399
E+N CG L++ PF+ C AV+ P +F CVYDLCA A LC +L AY + C
Sbjct: 2645 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLAAYTAAC 2701
Query: 1400 RQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPG 1458
+ AGV WR + C + CP + C RTC L L C C G
Sbjct: 2702 QAAGVAVKPWRTDSFCPLHCPAHSHYSI------CTRTCQGSCAALSGLTG-CTTRCFEG 2754
Query: 1459 CQCPAGLVEHEAHCIPPEAC 1478
C+C + + CIP + C
Sbjct: 2755 CECDDRFLLSQGVCIPVQDC 2774
Score = 199 bits (507), Expect = 1e-50
Identities = 132/388 (34%), Positives = 177/388 (45%), Gaps = 43/388 (11%)
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
+C C AG QRC + KA ++ + A C A GDPHY TFD
Sbjct: 443 SCEGMQCAAG------QRCQVVG---GKAGCVAEST---------AVCRAQGDPHYTTFD 484
Query: 1163 GRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ 1218
GR G+CSY + + C D FSV N+ RG V++ V V +V L +
Sbjct: 485 GRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTR 544
Query: 1219 D--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQ 1275
G V VD LP L E L V G ++ GL V +D Q+ +S+P +Q
Sbjct: 545 GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQ 604
Query: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PCRA 1334
+ CGLCGN+NG DD P+G L P F +SW++ +G + C G + + P
Sbjct: 605 DQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY---LCEDGCQNNCPACT 661
Query: 1335 AGYRARREANARCGVLK--SSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
G E + CG+L PF+ CH + P PF CVYDLC G LC L
Sbjct: 662 PGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG---GERLSLCRGL 718
Query: 1393 EAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
AYA C + G++ WR P C + CP ++ CGP CP +C P ++C
Sbjct: 719 SAYAQACLELGISVGDWRSPANCPLSCPANSR--YELCGPACPTSCNGAAAP-----SNC 771
Query: 1452 V-RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
RPCV GC C G V C+P +C
Sbjct: 772 SGRPCVEGCVCLPGFVASGGACVPASSC 799
Score = 195 bits (496), Expect = 2e-49
Identities = 169/577 (29%), Positives = 236/577 (40%), Gaps = 86/577 (14%)
Query: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
+C C C + + G F C P G P CH P G
Sbjct: 1858 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLASGTGGPFTTCHAHVPPESFFKG 1906
Query: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 1907 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 1966
Query: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
SCP T P G C C+ + R V A E W
Sbjct: 1967 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 2025
Query: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 2026 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 2081
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 2082 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 2141
Query: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
++ L + VDG VALPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 2142 SLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 2201
Query: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
P +Y CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 2202 PAAYAASLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 2252
Query: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 2253 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 2307
Query: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
LC A+ Y + C+ AG WR P C + CP ++ CG CP +C +
Sbjct: 2308 -----LCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSH--YELCGDSCPVSCPSLS 2360
Query: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
P G C C GC C AG V C+P C
Sbjct: 2361 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 2392
Score = 195 bits (495), Expect = 3e-49
Identities = 156/463 (33%), Positives = 205/463 (44%), Gaps = 58/463 (12%)
Query: 1055 HQACPELSCPLSERHTP-PGSCCPVCRA----------------PTQSC--VHQGREVAS 1095
++AC CPLS P PG C C P SC VHQG
Sbjct: 1142 YEAC-SYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
Query: 1096 GERWTVDT-CTS-CSCM-AGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CM 1151
G+ + C S C C G V C+S SCGP +A S GS C+ +S C
Sbjct: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESS-----SCGPHEACQPSGGSL--GCVAVGSSTCQ 1253
Query: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAV 1207
A GDPHY TFDGR F G+C YVLA+ C + F+V N G V+ T+ + V
Sbjct: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
Query: 1208 LLGDMAVRLLQ-DGAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQ 1265
+ + +RL Q VTV+G + LP L + G V++ GL+V +D
Sbjct: 1314 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQ---VSEGLWPGRP 1322
V V+VPG+Y + CGLCGN+NG +DD Q P G + FGNSW+ P P
Sbjct: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 1433
Query: 1323 CSAGRE-VDPCRAAGYRARREANAR--CGVLKS--SPFSRCHAVVPPEPFFAACVYDLCA 1377
C G E P ++ CG+L S P S CH +V P+ C++DLC
Sbjct: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493
Query: 1378 CGPGSSADACLCDALEAYASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPR 1435
G S LC + AY S C+ AG V P WR T C + CP ++ C C
Sbjct: 1494 GGGNLS---ILCSNIHAYVSACQAAGGHVEP-WRTETFCPMECPPNSH--YELCADTCSL 1547
Query: 1436 TCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
C P C C GCQC +G + + C+P + C
Sbjct: 1548 GCSALSAP-----PQCQDGCAEGCQCDSGFLYNGQACVPIQQC 1585
Score = 192 bits (488), Expect = 2e-48
Identities = 144/423 (34%), Positives = 195/423 (46%), Gaps = 41/423 (9%)
Query: 1073 GSCCPVCRAPTQSCVHQGREVASGER-WTVDTCTS-CSCMAGT--VRCQSQRCSPLSCGP 1128
G+C P A + C QG ++A G+ W + C C+C T V C+ ++ SC
Sbjct: 791 GACVP---ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ----SCPA 843
Query: 1129 DKAPALSPG--SCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD-- 1184
+ ++ G C P R +C GDPHY +FDGR F G+C+Y+L C
Sbjct: 844 GERCSVQNGLLGCYP---DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 1185 --FSVHVTNDDRGRSGVAWTQEVAVLLGDM--AVRLLQDGAVTVDGHPVALPF-LQEPLL 1239
F V V N+ RG V++T+ V V + AVR G V VD LPF + +
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
Query: 1240 YVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGL 1299
V +G ++ GL V +D ++V VP SY CGLCGNFNG DDL G
Sbjct: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
Query: 1300 LLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR-EANARCGVL--KSSPFS 1356
+ AFGNSWQ E PG C A D + A++ ++ CG+L PF
Sbjct: 1021 QAANALAFGNSWQ--EETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCV 1415
CH+ + P+ CVYD C PG S LCDAL YA+ C+ AG T WR LC
Sbjct: 1077 ECHSKLDPQGAVRDCVYDRCLL-PGQSGP--LCDALATYAAACQAAGATVHPWRSEELCP 1133
Query: 1416 VGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPP 1475
+ CP ++ C CP +C + +P G C C GC C G C+P
Sbjct: 1134 LSCPPHSH--YEACSYGCPLSCGDLPVPGG-----CGSECHEGCVCDEGFALSGESCLPL 1186
Query: 1476 EAC 1478
+C
Sbjct: 1187 ASC 1189
Score = 51.2 bits (121), Expect = 7e-06
Identities = 68/227 (29%), Positives = 81/227 (35%), Gaps = 40/227 (17%)
Query: 558 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA----PAGCPRPGAA-HA 612
P P R C + Q R CV C LLPG+ P C A A C GA H
Sbjct: 1071 PKGPFRECHSKL-DPQGAVRDCVYDRC----LLPGQSGPLCDALATYAAACQAAGATVHP 1125
Query: 613 RHQEYFSPPGDPCRRCL--CLDGS-VSCQRLPCPPAPCAHPRQGPCCP------------ 657
E P P C G +SC LP P + +G C
Sbjct: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLP 1185
Query: 658 --SCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKACAPALCPFPARGDCCP 714
SC GC++QG G+ F LC C EG VSCE +C P P+ G
Sbjct: 1186 LASC-GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSL-- 1242
Query: 715 DCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGRRP 755
GC +G S P D R + TC+ TCG RP
Sbjct: 1243 ---GCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1286
Score = 50.8 bits (120), Expect = 1e-05
Identities = 57/229 (24%), Positives = 85/229 (37%), Gaps = 21/229 (9%)
Query: 1073 GSCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDK 1130
G C PV C H GR + C+ CSC + + + CQ+ C P K
Sbjct: 2766 GVCIPVQDC---GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVK 2822
Query: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH-- 1188
A A + C C+ + TFDG Y L+ C ++
Sbjct: 2823 AEARN-------CWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWY 2875
Query: 1189 --VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELR-- 1244
V +V + D V L + V V+G V LP E L V +
Sbjct: 2876 RVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP--AEKLASVSVSRT 2933
Query: 1245 -GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDD 1292
++++ + G+QV +V V V + G+ CG CGNF+G +D
Sbjct: 2934 PDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982
Score = 47.4 bits (111), Expect = 1e-04
Identities = 49/191 (25%), Positives = 66/191 (34%), Gaps = 56/191 (29%)
Query: 299 IPGQCCPVCDG-------CEYQG---HQYQSQETFRLQERGLC-VRCSCQAGEVSCEEQE 347
+PGQ P+CD C+ G H ++S+E LC + C + +C
Sbjct: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--------LCPLSCPPHSHYEACS-YG 1148
Query: 348 CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAP 407
CP++ LP G C G E EG CVC +G G P A
Sbjct: 1149 CPLSCGDLPVPG-----GC---GSECHEG------------CVCDEGFALSGESCLPLAS 1188
Query: 408 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQD-GTVTCSLVDCPPTT 466
C C + + GQ F CHCQ+ G V+C C P
Sbjct: 1189 C---------------GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHE 1233
Query: 467 CARPQSGPGQC 477
+P G C
Sbjct: 1234 ACQPSGGSLGC 1244
Score = 46.6 bits (109), Expect = 2e-04
Identities = 67/243 (27%), Positives = 82/243 (33%), Gaps = 46/243 (18%)
Query: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
+G C KPCP P GP C V CH + + Q D
Sbjct: 2240 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2299
Query: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ +G P G C V+ C +L R CP C AH G
Sbjct: 2300 QVQGHPGGLCP-------AVATYVAACQAAGAQLGEWRRPDFCPL--QCPAHSHYELCGD 2350
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
+C S EG + R C+ G C P QC C H+GR Y GE
Sbjct: 2351 SC---PVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDGRYYPLGE 2405
Query: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQ--LLPPGPQHCCPT-CAEA 1022
F PG + CE CE P G + C C P + L G Q C T C
Sbjct: 2406 VFYPGPE-CE-RRCECGPGGHVT-------CQEGAACGPHEECRLEDGVQACHATGCGRC 2456
Query: 1023 LSN 1025
L+N
Sbjct: 2457 LAN 2459
Score = 45.8 bits (107), Expect = 3e-04
Identities = 62/256 (24%), Positives = 88/256 (34%), Gaps = 55/256 (21%)
Query: 643 PPAPCAHPRQGPCCPSCDGCL------------YQGKEFASGERFPS-PTAACHLC---- 685
P +PC P PC P + C+ YQ +EF P+ P ++CH
Sbjct: 1424 PDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 1481
Query: 686 ---------LCWEG---SVSCEP-----KACAPA---LCPFPARGDCCPDCDGCEYLGES 725
LC G S+ C AC A + P+ C +C
Sbjct: 1482 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP-------- 1533
Query: 726 YLSNQEFPDPREPCNL-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHG 782
N + + C+L C+ L C E C + +G C Q GC ++G
Sbjct: 1534 --PNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
Query: 783 VTTASGETLPDPLDPTCSLCTCQEGS-MRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQG 841
V +T+ +D CTC G M CQ+ C P PS G C C
Sbjct: 1592 VYYEPEQTVL--IDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVT 1649
Query: 842 REHQDGEEFEGPAGSC 857
Q+ + +G G C
Sbjct: 1650 CRPQETCKEQGGQGVC 1665
Score = 42.7 bits (99), Expect = 0.003
Identities = 60/218 (27%), Positives = 75/218 (34%), Gaps = 45/218 (20%)
Query: 660 DGCLYQGKEFASGERFPSPTAACHLCLC----WEGSVSCEPKACAPALCPFPARGDCCPD 715
D CL G+ + + AAC W C P CP + + C
Sbjct: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC------PLSCPPHSHYEACSY 1147
Query: 716 CDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCC--- 772
GC LS + P P GG CG E C SG C
Sbjct: 1148 --GCP------LSCGDLPVP----------GG---CGSECHEGCVCDEGFALSGESCLPL 1186
Query: 773 PTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGSM-RCQKKPCPPALCPHPSPGPCF 830
+C GC + G G+T P C SLC CQEG + C+ C P PS G
Sbjct: 1187 ASC-GCVHQGTYHPPGQTFYP--GPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
Query: 831 CPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
C S C + G H DG F+ G+C + Q
Sbjct: 1244 CVAVGSSTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 1280
Score = 42.0 bits (97), Expect = 0.004
Identities = 69/258 (26%), Positives = 88/258 (34%), Gaps = 54/258 (20%)
Query: 659 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
C C + + + FP+ T A + + W GS AP P C +C G
Sbjct: 1814 CGLCGNMDRNPNNDQVFPNGTLAPSIPI-WGGSWR------APGWDPL-----CWDECRG 1861
Query: 719 -CEYLGESYLSNQEFPDPREPCNLCTCLGG-FVTCGRRPCEPP-----GCSHPL-IPSGH 770
C E L E P P L + GG F TC PP GC + + G
Sbjct: 1862 SCPTCPEDRLEQYEGPGFCGP--LASGTGGPFTTCHAHV--PPESFFKGCVLDVCMGGGD 1917
Query: 771 CCPTCQG-CRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--- 826
C+ Y A+G + D TC E S P PA CP P+P
Sbjct: 1918 RDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTT 1977
Query: 827 -----GPCF---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQ 863
GPC C ++ C + G H+ G EF +WCRC
Sbjct: 1978 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 2037
Query: 864 AGQVSCVRLQCPPLPCKL 881
G S V C P C L
Sbjct: 2038 PGGGSLV---CTPASCGL 2052
Score = 41.2 bits (95), Expect = 0.008
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 1951 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 2000
Query: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 2001 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 2046
Query: 285 PLPC 288
P C
Sbjct: 2047 PASC 2050
Score = 40.0 bits (92), Expect = 0.017
Identities = 65/256 (25%), Positives = 77/256 (30%), Gaps = 71/256 (27%)
Query: 704 CPFPARGDCCPDCDGCEYLGESYLSNQE---FPDPREPCNLCTCL----GGFVTCGRRPC 756
C GDC P D + + S E DP+ P C G C C
Sbjct: 1040 CGATEPGDC-PKLDSL--VAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
Query: 757 EPPGCSHPLIPSGHCCPTCQGCRYHGVTT---ASGETLPDPLDPTCSLCTCQEGSMRCQK 813
PG S PL + C+ G T S E P P C G
Sbjct: 1097 LLPGQSGPLCDA--LATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYG------ 1148
Query: 814 KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
CP + P PG C CH E C C G +
Sbjct: 1149 --CPLSCGDLPVPGGCGSE-CH----------------------EGCVCDEG-FALSGES 1182
Query: 874 CPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHE-GVVTCARIQ 932
C PL SC GC+ G HP G + P S C C E G+V+C
Sbjct: 1183 CLPL---------ASC-----GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSS 1228
Query: 933 CISSCAQPRQGPHDCC 948
C GPH+ C
Sbjct: 1229 C---------GPHEAC 1235
Score = 38.1 bits (87), Expect = 0.065
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 15/97 (15%)
Query: 910 VPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCS-DCEHEGRKYEPGESFQ 968
+P C S CHEG V C +S C P S C H+G + PG++F
Sbjct: 1156 LPVPGGCGS-ECHEGCV-CDEGFALSG--------ESCLPLASCGCVHQGTYHPPGQTFY 1205
Query: 969 PGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005
PG +C C+ EG + C C C PS
Sbjct: 1206 PGPGCDSLCHCQ---EG-GLVSCESSSCGPHEACQPS 1238
Score = 37.7 bits (86), Expect = 0.084
Identities = 65/243 (26%), Positives = 82/243 (33%), Gaps = 62/243 (25%)
Query: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 2241 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 2285
Query: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
P C A + +P G P+ + C + Q R PL CP
Sbjct: 2286 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLGEWRRPDFCPLQCPAH 2342
Query: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
L G+ CP CP AP GC CR C+C G V
Sbjct: 2343 SHYELCGDSCPVSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 2385
Query: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSC-EPKA 698
P C GCL+ G+ + GE F C C G V+C E A
Sbjct: 2386 CVPVGQC-------------GCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 2432
Query: 699 CAP 701
C P
Sbjct: 2433 CGP 2435
Score = 37.0 bits (84), Expect = 0.14
Identities = 57/200 (28%), Positives = 70/200 (35%), Gaps = 50/200 (25%)
Query: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------CFLNG---RE 258
P P R C H + + C Y LPG P+CD C G
Sbjct: 1071 PKGPFREC-----HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1125
Query: 259 HRSGE--PVGSGDPCSHCR-CANGSVQCEPLPCPPVPCRHPGKIPGQCCP--VCD----- 308
RS E P+ S P SH C+ G PL C +P PG +C VCD
Sbjct: 1126 WRSEELCPL-SCPPHSHYEACSYGC----PLSCGDLPV--PGGCGSECHEGCVCDEGFAL 1178
Query: 309 -----------GCEYQGHQYQSQETFRLQERGLCVRCSCQAGE-VSCEEQECPVTPCALP 356
GC +QG + +TF G C CQ G VSCE C P
Sbjct: 1179 SGESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
Query: 357 ASGRQLCPA-----CELDGE 371
+ G C A C+ G+
Sbjct: 1238 SGGSLGCVAVGSSTCQASGD 1257
Score = 36.2 bits (82), Expect = 0.25
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 104 PEGARWEPDACT-ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETF--SPDACTTCR 160
PEG AC CVC G G GC +G+ Y GE F P+ C
Sbjct: 2362 PEGCE---SACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
Query: 161 CLTGA-VQCQ-----GP--SCSELNCLESCTPPGECCPICCTEGGSHW 200
C G V CQ GP C + +++C G C C GG H+
Sbjct: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATG--CGRCLANGGIHY 2464
Score = 35.8 bits (81), Expect = 0.32
Identities = 118/496 (23%), Positives = 154/496 (31%), Gaps = 95/496 (19%)
Query: 117 CVCQDG----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTT--CRCLTGAVQCQG 170
C C G A C P L + GC NG + G F D + CRC G
Sbjct: 1989 CQCDAGFVLSADRCVP---LNNGCGCWANGTYHEAGSEFWADGTCSQWCRC--------G 2037
Query: 171 PSCSELNCLESCTPPGECCPICCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
P L C + GE C + + + G E GDP + L+GH Q
Sbjct: 2038 PGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT--LDGHRFDFQGT 2095
Query: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
C L P P + EHR + V S+ R + L
Sbjct: 2096 CEYLLSAPCHGPP---LGAENFTVTVANEHRGSQAV------SYTRSVTLQIYNHSLT-- 2144
Query: 290 PVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECP 349
+ R P K+ DG + +Q G V + +G + +
Sbjct: 2145 -LSARWPRKLQ------VDGV-FVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2196
Query: 350 V---TPCALPASGRQLCPACELDGEEFAEGVQWEPDG------RPCTACVCQD------- 393
V P A AS LC D + + V +P G + C CV +
Sbjct: 2197 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP 2256
Query: 394 -------GVPKCGAVLC---PPAPCQHPTQPPGACCPSC--DSCTYHSQVYANGQNFTDA 441
G CG + P APC H PP C D+C
Sbjct: 2257 EQQESFGGPDACGVISATDGPLAPC-HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
Query: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPR 501
+ C A Q G RP P QC + + V S S P
Sbjct: 2316 VAACQAAGAQLGE------------WRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP- 2362
Query: 502 DPCQECRCQEGHAHCQPRPCPRAPCAHPLPG-TCCPNDCSGCAFGGKEYPSGADFPHPSD 560
+ C E C+EG L G TC P GC G+ YP G F +P
Sbjct: 2363 EGC-ESACREGCV---------CDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF-YPGP 2411
Query: 561 PC-RLCRC-LSGNVQC 574
C R C C G+V C
Sbjct: 2412 ECERRCECGPGGHVTC 2427
Score = 35.4 bits (80), Expect = 0.42
Identities = 62/239 (25%), Positives = 79/239 (33%), Gaps = 53/239 (22%)
Query: 374 AEGVQWEPDGRPCTACVCQDGVPK--------------CGAVLCPPAP---CQHPTQPPG 416
A G W+ + RP PK CG + P P C P G
Sbjct: 1027 AFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQG 1086
Query: 417 ACCPSCDSCTYHSQVYANGQNFTDADS-PCHACHCQDGTVTCS---LVDCPPTTCARPQS 472
A C Y + GQ+ D+ +A CQ T + P +C P S
Sbjct: 1087 AV----RDCVY-DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP-PHS 1140
Query: 473 GPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE-CRCQEGHAHCQPRPCPRAPCAHPLP 531
C CP + ++ V G S C E C C EG A L
Sbjct: 1141 HYEACSYGCP--LSCGDLPVPGGCGSE----CHEGCVCDEGFA---------------LS 1179
Query: 532 G-TCCPNDCSGCAFGGKEYPSGADFPHPSDPC-RLCRCLSGN-VQCLARRCVPLPCPEP 587
G +C P GC G +P G F +P C LC C G V C + C P +P
Sbjct: 1180 GESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
Score = 34.7 bits (78), Expect = 0.71
Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 35/152 (23%)
Query: 564 LCRCLSGNVQCLARRCVPL-----PCPEPVLLPGE-----CCPQCPAPAGCPRPGAAHAR 613
LCR LS Q + + P P+ P C P CP GAA
Sbjct: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCN----GAAAPS 769
Query: 614 HQEYFSPPGDPC-RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASG 672
+ G PC C+CL G V+ P + C GC +QG + A G
Sbjct: 770 NCS-----GRPCVEGCVCLPGFVASGGACVPASSC-------------GCTFQGLQLAPG 811
Query: 673 ERFPSPTAACHLCLCWEGS--VSCEPKACAPA 702
+ + C C + V+C K PA
Sbjct: 812 QEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
Score = 33.9 bits (76), Expect = 1.2
Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 42/184 (22%)
Query: 688 WEGSVSCEPKACAPALCPFPARGDCCP-DCDGCEYLGESYLSNQEFPDPREPC-NLCTCL 745
W +C P +C PA + G CP C+G S S + PC C CL
Sbjct: 735 WRSPANC-PLSC-PANSRYELCGPACPTSCNGAA--APSNCSGR-------PCVEGCVCL 783
Query: 746 GGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS-LCT 803
GFV G G C P GC + G+ A G+ + D C CT
Sbjct: 784 PGFVASG----------------GACVPASSCGCTFQGLQLAPGQEV--WADELCQRRCT 825
Query: 804 CQEGS--MRCQ-KKPCPPALCPHPSPG--PCFCPVCHSCLSQGREHQ---DGEEFEGPAG 855
C + + C+ K+ CP G C+ +C G H DG F+ G
Sbjct: 826 CNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF-MG 884
Query: 856 SCEW 859
+C +
Sbjct: 885 TCTY 888
Score = 33.5 bits (75), Expect = 1.6
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 1966 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 2023
Query: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
+ G + CRC G + C C
Sbjct: 2024 FWADGTCSQWCRCGPGGGSLVCTPASC 2050
Score = 31.6 bits (70), Expect = 6.0
Identities = 51/225 (22%), Positives = 66/225 (29%), Gaps = 36/225 (16%)
Query: 287 PC-PPVPCRHPGK---IPGQCCPVCDGCEYQGHQY---QSQETFRLQERGL--------- 330
PC PP PC PG IP CP +YQ ++ S T L
Sbjct: 1427 PCLPPTPCP-PGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLK 1485
Query: 331 -CVRCSCQAG---EVSCEEQECPVTPCAL------PASGRQLCPACELDGEEFAEGVQWE 380
C+ C G + C V+ C P CP E +E
Sbjct: 1486 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM------ECPPNSHYE 1539
Query: 381 PDGRPCT-ACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSC-TYHSQVYANGQNF 438
C+ C P+C C G C C YH+ VY +
Sbjct: 1540 LCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQT 1599
Query: 439 TDADSPCHACHCQDGT-VTCSLVDCPPTTCARPQSGPGQCCPRCP 482
D+ C C G + C C P +P G C + P
Sbjct: 1600 VLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDP 1644
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 199 bits (507), Expect = 1e-50
Identities = 132/388 (34%), Positives = 177/388 (45%), Gaps = 43/388 (11%)
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
+C C AG QRC + KA ++ + A C A GDPHY TFD
Sbjct: 504 SCEGMQCAAG------QRCQVVG---GKAGCVAEST---------AVCRAQGDPHYTTFD 545
Query: 1163 GRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ 1218
GR G+CSY + + C D FSV N+ RG V++ V V +V L +
Sbjct: 546 GRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTR 605
Query: 1219 D--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQ 1275
G V VD LP L E L V G ++ GL V +D Q+ +S+P +Q
Sbjct: 606 GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQ 665
Query: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PCRA 1334
+ CGLCGN+NG DD P+G L P F +SW++ +G + C G + + P
Sbjct: 666 DQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY---LCEDGCQNNCPACT 722
Query: 1335 AGYRARREANARCGVLK--SSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
G E + CG+L PF+ CH + P PF CVYDLC G LC L
Sbjct: 723 PGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG---GERLSLCRGL 779
Query: 1393 EAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
AYA C + G++ WR P C + CP ++ CGP CP +C P ++C
Sbjct: 780 SAYAQACLELGISVGDWRSPANCPLSCPANSR--YELCGPACPTSCNGAAAP-----SNC 832
Query: 1452 V-RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
RPCV GC C G V C+P +C
Sbjct: 833 SGRPCVEGCVCLPGFVASGGACVPASSC 860
Score = 192 bits (488), Expect = 2e-48
Identities = 144/423 (34%), Positives = 195/423 (46%), Gaps = 41/423 (9%)
Query: 1073 GSCCPVCRAPTQSCVHQGREVASGER-WTVDTCTS-CSCMAGT--VRCQSQRCSPLSCGP 1128
G+C P A + C QG ++A G+ W + C C+C T V C+ ++ SC
Sbjct: 852 GACVP---ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ----SCPA 904
Query: 1129 DKAPALSPG--SCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD-- 1184
+ ++ G C P R +C GDPHY +FDGR F G+C+Y+L C
Sbjct: 905 GERCSVQNGLLGCYP---DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
Query: 1185 --FSVHVTNDDRGRSGVAWTQEVAVLLGDM--AVRLLQDGAVTVDGHPVALPF-LQEPLL 1239
F V V N+ RG V++T+ V V + AVR G V VD LPF + +
Sbjct: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 1021
Query: 1240 YVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGL 1299
V +G ++ GL V +D ++V VP SY CGLCGNFNG DDL G
Sbjct: 1022 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1081
Query: 1300 LLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR-EANARCGVL--KSSPFS 1356
+ AFGNSWQ E PG C A D + A++ ++ CG+L PF
Sbjct: 1082 QAANALAFGNSWQ--EETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1137
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCV 1415
CH+ + P+ CVYD C PG S LCDAL YA+ C+ AG T WR LC
Sbjct: 1138 ECHSKLDPQGAVRDCVYDRCLL-PGQSGP--LCDALATYAAACQAAGATVHPWRSEELCP 1194
Query: 1416 VGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPP 1475
+ CP ++ C CP +C + +P G C C GC C G C+P
Sbjct: 1195 LSCPPHSH--YEACSYGCPLSCGDLPVPGG-----CGSECHEGCVCDEGFALSGESCLPL 1247
Query: 1476 EAC 1478
+C
Sbjct: 1248 ASC 1250
Score = 73.9 bits (180), Expect = 1e-12
Identities = 67/191 (35%), Positives = 85/191 (44%), Gaps = 35/191 (18%)
Query: 1055 HQACPELSCPLSERHTP-PGSCCPVCRA----------------PTQSC--VHQGREVAS 1095
++AC CPLS P PG C C P SC VHQG
Sbjct: 1203 YEAC-SYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1261
Query: 1096 GERWTVDT-CTS-CSCM-AGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CM 1151
G+ + C S C C G V C+S SCGP +A S GS C+ +S C
Sbjct: 1262 GQTFYPGPGCDSLCHCQEGGLVSCESS-----SCGPHEACQPSGGSL--GCVAVGSSTCQ 1314
Query: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAV 1207
A GDPHY TFDGR F G+C YVLA+ C + F+V N G V+ T+ + V
Sbjct: 1315 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374
Query: 1208 LLGDMAVRLLQ 1218
+ + +RL Q
Sbjct: 1375 QVANFTLRLEQ 1385
Score = 51.2 bits (121), Expect = 7e-06
Identities = 68/227 (29%), Positives = 81/227 (35%), Gaps = 40/227 (17%)
Query: 558 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA----PAGCPRPGAA-HA 612
P P R C + Q R CV C LLPG+ P C A A C GA H
Sbjct: 1132 PKGPFRECHSKL-DPQGAVRDCVYDRC----LLPGQSGPLCDALATYAAACQAAGATVHP 1186
Query: 613 RHQEYFSPPGDPCRRCL--CLDGS-VSCQRLPCPPAPCAHPRQGPCCP------------ 657
E P P C G +SC LP P + +G C
Sbjct: 1187 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLP 1246
Query: 658 --SCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKACAPALCPFPARGDCCP 714
SC GC++QG G+ F LC C EG VSCE +C P P+ G
Sbjct: 1247 LASC-GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSL-- 1303
Query: 715 DCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGRRP 755
GC +G S P D R + TC+ TCG RP
Sbjct: 1304 ---GCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347
Score = 47.4 bits (111), Expect = 1e-04
Identities = 49/191 (25%), Positives = 66/191 (34%), Gaps = 56/191 (29%)
Query: 299 IPGQCCPVCDG-------CEYQG---HQYQSQETFRLQERGLC-VRCSCQAGEVSCEEQE 347
+PGQ P+CD C+ G H ++S+E LC + C + +C
Sbjct: 1159 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--------LCPLSCPPHSHYEACS-YG 1209
Query: 348 CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAP 407
CP++ LP G C G E EG CVC +G G P A
Sbjct: 1210 CPLSCGDLPVPG-----GC---GSECHEG------------CVCDEGFALSGESCLPLAS 1249
Query: 408 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQD-GTVTCSLVDCPPTT 466
C C + + GQ F CHCQ+ G V+C C P
Sbjct: 1250 C---------------GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHE 1294
Query: 467 CARPQSGPGQC 477
+P G C
Sbjct: 1295 ACQPSGGSLGC 1305
Score = 42.7 bits (99), Expect = 0.003
Identities = 60/218 (27%), Positives = 75/218 (34%), Gaps = 45/218 (20%)
Query: 660 DGCLYQGKEFASGERFPSPTAACHLCLC----WEGSVSCEPKACAPALCPFPARGDCCPD 715
D CL G+ + + AAC W C P CP + + C
Sbjct: 1155 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC------PLSCPPHSHYEACSY 1208
Query: 716 CDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCC--- 772
GC LS + P P GG CG E C SG C
Sbjct: 1209 --GCP------LSCGDLPVP----------GG---CGSECHEGCVCDEGFALSGESCLPL 1247
Query: 773 PTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGSM-RCQKKPCPPALCPHPSPGPCF 830
+C GC + G G+T P C SLC CQEG + C+ C P PS G
Sbjct: 1248 ASC-GCVHQGTYHPPGQTFYP--GPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1304
Query: 831 CPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
C S C + G H DG F+ G+C + Q
Sbjct: 1305 CVAVGSSTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 1341
Score = 40.0 bits (92), Expect = 0.017
Identities = 65/256 (25%), Positives = 77/256 (30%), Gaps = 71/256 (27%)
Query: 704 CPFPARGDCCPDCDGCEYLGESYLSNQE---FPDPREPCNLCTCL----GGFVTCGRRPC 756
C GDC P D + + S E DP+ P C G C C
Sbjct: 1101 CGATEPGDC-PKLDSL--VAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1157
Query: 757 EPPGCSHPLIPSGHCCPTCQGCRYHGVTT---ASGETLPDPLDPTCSLCTCQEGSMRCQK 813
PG S PL + C+ G T S E P P C G
Sbjct: 1158 LLPGQSGPLCDA--LATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYG------ 1209
Query: 814 KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
CP + P PG C CH E C C G +
Sbjct: 1210 --CPLSCGDLPVPGGCGSE-CH----------------------EGCVCDEG-FALSGES 1243
Query: 874 CPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHE-GVVTCARIQ 932
C PL SC GC+ G HP G + P S C C E G+V+C
Sbjct: 1244 CLPL---------ASC-----GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSS 1289
Query: 933 CISSCAQPRQGPHDCC 948
C GPH+ C
Sbjct: 1290 C---------GPHEAC 1296
Score = 38.1 bits (87), Expect = 0.065
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 15/97 (15%)
Query: 910 VPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCS-DCEHEGRKYEPGESFQ 968
+P C S CHEG V C +S C P S C H+G + PG++F
Sbjct: 1217 LPVPGGCGS-ECHEGCV-CDEGFALSG--------ESCLPLASCGCVHQGTYHPPGQTFY 1266
Query: 969 PGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005
PG +C C+ EG + C C C PS
Sbjct: 1267 PGPGCDSLCHCQ---EG-GLVSCESSSCGPHEACQPS 1299
Score = 37.0 bits (84), Expect = 0.14
Identities = 57/200 (28%), Positives = 70/200 (35%), Gaps = 50/200 (25%)
Query: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------CFLNG---RE 258
P P R C H + + C Y LPG P+CD C G
Sbjct: 1132 PKGPFREC-----HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1186
Query: 259 HRSGE--PVGSGDPCSHCR-CANGSVQCEPLPCPPVPCRHPGKIPGQCCP--VCD----- 308
RS E P+ S P SH C+ G PL C +P PG +C VCD
Sbjct: 1187 WRSEELCPL-SCPPHSHYEACSYGC----PLSCGDLPV--PGGCGSECHEGCVCDEGFAL 1239
Query: 309 -----------GCEYQGHQYQSQETFRLQERGLCVRCSCQAGE-VSCEEQECPVTPCALP 356
GC +QG + +TF G C CQ G VSCE C P
Sbjct: 1240 SGESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1298
Query: 357 ASGRQLCPA-----CELDGE 371
+ G C A C+ G+
Sbjct: 1299 SGGSLGCVAVGSSTCQASGD 1318
Score = 35.4 bits (80), Expect = 0.42
Identities = 62/239 (25%), Positives = 79/239 (33%), Gaps = 53/239 (22%)
Query: 374 AEGVQWEPDGRPCTACVCQDGVPK--------------CGAVLCPPAP---CQHPTQPPG 416
A G W+ + RP PK CG + P P C P G
Sbjct: 1088 AFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQG 1147
Query: 417 ACCPSCDSCTYHSQVYANGQNFTDADS-PCHACHCQDGTVTCS---LVDCPPTTCARPQS 472
A C Y + GQ+ D+ +A CQ T + P +C P S
Sbjct: 1148 AV----RDCVY-DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP-PHS 1201
Query: 473 GPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE-CRCQEGHAHCQPRPCPRAPCAHPLP 531
C CP + ++ V G S C E C C EG A L
Sbjct: 1202 HYEACSYGCP--LSCGDLPVPGGCGSE----CHEGCVCDEGFA---------------LS 1240
Query: 532 G-TCCPNDCSGCAFGGKEYPSGADFPHPSDPC-RLCRCLSGN-VQCLARRCVPLPCPEP 587
G +C P GC G +P G F +P C LC C G V C + C P +P
Sbjct: 1241 GESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1298
Score = 34.7 bits (78), Expect = 0.71
Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 35/152 (23%)
Query: 564 LCRCLSGNVQCLARRCVPL-----PCPEPVLLPGE-----CCPQCPAPAGCPRPGAAHAR 613
LCR LS Q + + P P+ P C P CP GAA
Sbjct: 775 LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCN----GAAAPS 830
Query: 614 HQEYFSPPGDPC-RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASG 672
+ G PC C+CL G V+ P + C GC +QG + A G
Sbjct: 831 NCS-----GRPCVEGCVCLPGFVASGGACVPASSC-------------GCTFQGLQLAPG 872
Query: 673 ERFPSPTAACHLCLCWEGS--VSCEPKACAPA 702
+ + C C + V+C K PA
Sbjct: 873 QEVWADELCQRRCTCNGATHQVTCRDKQSCPA 904
Score = 33.9 bits (76), Expect = 1.2
Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 42/184 (22%)
Query: 688 WEGSVSCEPKACAPALCPFPARGDCCP-DCDGCEYLGESYLSNQEFPDPREPC-NLCTCL 745
W +C P +C PA + G CP C+G S S + PC C CL
Sbjct: 796 WRSPANC-PLSC-PANSRYELCGPACPTSCNGAA--APSNCSGR-------PCVEGCVCL 844
Query: 746 GGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS-LCT 803
GFV G G C P GC + G+ A G+ + D C CT
Sbjct: 845 PGFVASG----------------GACVPASSCGCTFQGLQLAPGQEV--WADELCQRRCT 886
Query: 804 CQEGS--MRCQ-KKPCPPALCPHPSPG--PCFCPVCHSCLSQGREHQ---DGEEFEGPAG 855
C + + C+ K+ CP G C+ +C G H DG F+ G
Sbjct: 887 CNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF-MG 945
Query: 856 SCEW 859
+C +
Sbjct: 946 TCTY 949
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 199 bits (505), Expect = 2e-50
Identities = 194/766 (25%), Positives = 266/766 (34%), Gaps = 199/766 (25%)
Query: 149 ETFSPDACTTCRCLTGAVQCQGPSCSELNCL-ESCTPPGECCPI--------------CC 193
E PD C+ RC VQ P C E + L E PPGECCP+ C
Sbjct: 168 EEEKPD-CSKARC---EVQFS-PRCPEDSVLIEGYAPPGECCPLPSRCVCNPAGCLRKVC 222
Query: 194 TEGGSHWEHGQEWTTPGDPCRICRCLEGH-IQCRQRECASLCPYPARPLPGTCCPVCDGC 252
G + + PG+ C + C + CR EC P+ T CP
Sbjct: 223 QPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECP--------PVQQTACP----- 269
Query: 253 FLNGREHRSGEPVGSGDPC----SHCRCANGSV---QCEPLPCPPVPCRHPGKIPGQCCP 305
+ + + D C + C C +G CE P + R G PG+CC
Sbjct: 270 ----PDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDG-TPGKCCD 324
Query: 306 VCD-------GCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCA---L 355
V + C + +Y + FR+ C C CQ G C +C C +
Sbjct: 325 VFECVNDTKPACVFNNVEYYDGDMFRMDN---CRFCRCQGGVAICFTAQCGEINCERYYV 381
Query: 356 PASGRQLCPACE-------------LDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVL 402
P + CP CE +G A G +W D CT C C +G C A +
Sbjct: 382 PEG--ECCPVCEDPVYPFNNPAGCYANGLILAHGDRWRED--DCTFCQCVNGERHCVATV 437
Query: 403 CPPAPCQHPTQPPGACCPSCD----------------SCTYHSQVYANGQNFTDADSPCH 446
C C +P + PG CCP C+ +CT + NG F + C
Sbjct: 438 CGQT-CTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCING--FKRDHNGCR 494
Query: 447 ACHCQDGTVTCS------LVDCP------------------PTTCARPQSGPGQC----- 477
C C + CS ++CP P C RP C
Sbjct: 495 TCQCINTEELCSERKQGCTLNCPFGFLTDAQNCEICECRPRPKKC-RPIICDKYCPLGLL 553
Query: 478 ----------CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
C +CP+ + + + SH C C+C+E A P
Sbjct: 554 KNKHGCDICRCKKCPELSCSKICPLGFQQDSH---GCLICKCREASASAGP--------- 601
Query: 528 HPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEP 587
L GTC D G + + + D CR C CL+G C C C P
Sbjct: 602 PILSGTCLTVD-------GHHHKNEESW---HDGCRECYCLNGREMCALITCPVPACGNP 651
Query: 588 VLLPGECCPQC-----------PAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVS 636
+ PG+CCP C P+ C PG + E ++ D C +C C G V
Sbjct: 652 TIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNI--DSCTQCTCHSGRVL 709
Query: 637 CQRLPCPPAPCAHP--RQGPCCPSCDGCLY-----------------QGKEFASGERFPS 677
C+ CPP C +P Q CCP C + +G F + E +
Sbjct: 710 CETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKP 769
Query: 678 PTAACHLCLCWEGSVSCEPKACAPALCPFPA--RGDCCPDC--DGCEYLGESYLSNQEFP 733
C C+C + +SC ++C C P +G CCP C D + S + +
Sbjct: 770 D--VCTSCICIDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVVCHFSGKAYA 827
Query: 734 DPR----EPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTC 775
D + C C CL G C C P C P+ G CCP C
Sbjct: 828 DEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMC 873
Score = 197 bits (500), Expect = 8e-50
Identities = 145/544 (26%), Positives = 186/544 (34%), Gaps = 153/544 (28%)
Query: 138 CSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPIC----- 192
C N Y +G+ F D C CRC G C C E+NC P GECCP+C
Sbjct: 336 CVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVY 395
Query: 193 -------CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTC 245
C G HG W D C C+C+ G C C C P + +PG C
Sbjct: 396 PFNNPAGCYANGLILAHGDRWRE--DDCTFCQCVNGERHCVATVCGQTCTNPVK-VPGEC 452
Query: 246 CPVCD----------------GCFLNGREHRSGEPVGSGDPCSHCRCAN----------- 278
CPVC+ C L G++ +G + C C+C N
Sbjct: 453 CPVCEEPTIITVDPPACGELSNCTLTGKDCINGFK-RDHNGCRTCQCINTEELCSERKQG 511
Query: 279 -----------GSVQCEPLPCPPVPCRHPGKIPGQCCPV--------CDGCEYQ------ 313
+ CE C P P + I + CP+ CD C +
Sbjct: 512 CTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELS 571
Query: 314 -------GHQYQSQETFRLQER------------GLCV------------------RCSC 336
G Q S + R G C+ C C
Sbjct: 572 CSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYC 631
Query: 337 QAGEVSCEEQECPVTPCALPA-SGRQLCPACELD------------------GEEFAEGV 377
G C CPV C P Q CP+C D GE F EG
Sbjct: 632 LNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGE 691
Query: 378 QWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYAN--- 434
W D CT C C G C +CPP CQ+P++ +CCP C + + N
Sbjct: 692 TWNIDS--CTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSV 749
Query: 435 --------GQNFTDADS----PCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP 482
G F A+S C +C C D ++C CP +C RP GQCCP C
Sbjct: 750 PNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQCCPYCI 809
Query: 483 D--------CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL--PG 532
+ C + + D E + D C C C +G C CP PC P+ G
Sbjct: 810 EDTIPKKVVCHFSGKAYADEERWD--LDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEG 867
Query: 533 TCCP 536
+CCP
Sbjct: 868 SCCP 871
Score = 194 bits (493), Expect = 5e-49
Identities = 150/575 (26%), Positives = 203/575 (35%), Gaps = 173/575 (30%)
Query: 88 EC-HPASPQCWGLGRAWPEGARWEPDACTACVCQDGAA-----HCG---------PQAHL 132
EC + P C + +G + D C C CQ G A CG P+
Sbjct: 327 ECVNDTKPACVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPEGEC 386
Query: 133 -PHCR----------GCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLES 181
P C GC NG +G+ + D CT C+C+ G C C + C
Sbjct: 387 CPVCEDPVYPFNNPAGCYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQ-TCTNP 445
Query: 182 CTPPGECCPIC------------------CTEGGSHWEHGQEWTTPGDPCRICRCLEGHI 223
PGECCP+C CT G +G + G CR C+C+
Sbjct: 446 VKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNG--CRTCQCINTEE 503
Query: 224 QCRQRE--CASLCPY------------PARPLPGTCCP-VCD------------------ 250
C +R+ C CP+ RP P C P +CD
Sbjct: 504 LCSERKQGCTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICR 563
Query: 251 ----------------------GCFL---NGREHRSGEPVGSG----------------- 268
GC + +G P+ SG
Sbjct: 564 CKKCPELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWH 623
Query: 269 DPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDG--------------CEYQG 314
D C C C NG C + CP C +P PGQCCP C C G
Sbjct: 624 DGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPG 683
Query: 315 HQYQSQ-ETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGR-QLCPAC------ 366
+Y + ET+ + C +C+C +G V CE + CP C P+ + CP C
Sbjct: 684 GEYFVEGETWNIDS---CTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFR 740
Query: 367 --------------ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPT 412
+G+ F W+PD CT+C+C D V C + CP C+ P
Sbjct: 741 PSLSRNNSVPNYCKNDEGDIFLAAESWKPD--VCTSCICIDSVISCFSESCPSVSCERPV 798
Query: 413 QPPGACCPSCDS--------CTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPP 464
G CCP C C + + YA+ + + D DS C C+C G CS V CPP
Sbjct: 799 LRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERW-DLDS-CTHCYCLQGQTLCSTVSCPP 856
Query: 465 TTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSH 499
C P + G CCP CP+ + E + E +H
Sbjct: 857 LPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNH 891
Score = 190 bits (483), Expect = 8e-48
Identities = 200/813 (24%), Positives = 272/813 (33%), Gaps = 207/813 (25%)
Query: 216 CRCLEGHIQCRQ-RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHC 274
C + G +C R C++ +P++ D C + +P CS
Sbjct: 133 CNIINGKCECNTIRTCSNPFEFPSQ----------DMCLSALKRIEEEKP-----DCSKA 177
Query: 275 RCANGSVQCEPLPCPPVPCRHPGKIP-GQCCPVCDGCEYQGHQYQSQETFRLQERGLCVR 333
RC VQ P CP G P G+CCP+ C + C+R
Sbjct: 178 RC---EVQFSPR-CPEDSVLIEGYAPPGECCPLPSRC--------------VCNPAGCLR 219
Query: 334 CSCQAGEVS-------------CEEQEC-PV-----TPCALPASGRQLCPACELDGEEFA 374
CQ G ++ C+ EC PV P + CP + +
Sbjct: 220 KVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQQTACPP-----DSYE 274
Query: 375 EGVQWEPDGRPC----TACVCQDGVPKCGAVLCP----PAPCQHPTQPPGACCPSCD--- 423
V+ DG C T C C G+ CG +C P PG CC +
Sbjct: 275 TQVRLTADG--CCTLPTRCECLSGL--CGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVN 330
Query: 424 ----SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP 479
+C +++ Y +G F + C C CQ G C C C R G+CCP
Sbjct: 331 DTKPACVFNNVEYYDGDMFRMDN--CRFCRCQGGVAICFTAQCGEINCERYYVPEGECCP 388
Query: 480 RCPD----------CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHP 529
C D C + G+ + D C C+C G HC C + C +P
Sbjct: 389 VCEDPVYPFNNPAGCYANGLILAHGDRWRE--DDCTFCQCVNGERHCVATVCGQT-CTNP 445
Query: 530 L--PGTCCP---------------NDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNV 572
+ PG CCP + S C GK+ +G F + CR C+C++
Sbjct: 446 VKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCING--FKRDHNGCRTCQCINTEE 503
Query: 573 QCLARR--CVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPG-------- 622
C R+ C L CP L + C C PRP + + P G
Sbjct: 504 LCSERKQGCT-LNCPFGFLTDAQNCEICECR---PRPKKCRPIICDKYCPLGLLKNKHGC 559
Query: 623 DPCRRCLCLDGSVSCQRLPCP------------------PAPCAHPRQGPCCPSCDGCLY 664
D CR C + +SC ++ CP A P C + DG +
Sbjct: 560 DICRCKKCPE--LSCSKI-CPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHH 616
Query: 665 QGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPA--RGDCCPDCDG---- 718
+ +E S C C C G C C C P G CCP C
Sbjct: 617 KNEE--------SWHDGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVV 668
Query: 719 ----------CEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPS 768
C G Y E + + C CTC G V C C P C +P
Sbjct: 669 QKPELSTPSICHAPGGEYFVEGETWNI-DSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQ 727
Query: 769 GHCCPTCQGCRYH------------------GVTTASGETLPDPLDPTCSLCTCQEGSMR 810
CCP C + + A+ PD C+ C C + +
Sbjct: 728 DSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPD----VCTSCICIDSVIS 783
Query: 811 CQKKPCPPALCPHP--SPGPCFCPVCHS--------CLSQGREHQDGEEFEGPAGSCEWC 860
C + CP C P G C CP C C G+ + D E ++ SC C
Sbjct: 784 CFSESCPSVSCERPVLRKGQC-CPYCIEDTIPKKVVCHFSGKAYADEERWD--LDSCTHC 840
Query: 861 RCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRC 893
C GQ C + CPPLPC + GSCCP C
Sbjct: 841 YCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMC 873
Score = 187 bits (475), Expect = 7e-47
Identities = 219/884 (24%), Positives = 287/884 (32%), Gaps = 256/884 (28%)
Query: 423 DSCTYHSQVYANGQNFTDAD----SPCH-----ACHCQDGTVTCSLVDCPPTTCARPQSG 473
DS T + +N+TD PC+ C+ +G C+ + TC+ P
Sbjct: 99 DSLTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTI----RTCSNPFEF 154
Query: 474 PGQ-------------------------CCPRCPDCILEEEVFVDGESFSHPRDPCQECR 508
P Q PRCP E+ V ++G + P EC
Sbjct: 155 PSQDMCLSALKRIEEEKPDCSKARCEVQFSPRCP----EDSVLIEGYA------PPGECC 204
Query: 509 CQEGHAHCQPRPCPRAPC-----------AHPLPGTCCP-NDCS---GCAFGGKEYPSGA 553
C P C R C A PG CC +C G E P
Sbjct: 205 PLPSRCVCNPAGCLRKVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQ 264
Query: 554 DFPHPSDP------------CRL---CRCLSGNVQCLARRCVPLPCPEPVL----LPGEC 594
P D C L C CLSG C C P V PG+C
Sbjct: 265 QTACPPDSYETQVRLTADGCCTLPTRCECLSG--LCGFPVCEVGSTPRIVSRGDGTPGKC 322
Query: 595 CP--QCPAPAGCPRPGAAHARHQEYFSPPG---DPCRRCLCLDGSVSCQRLPCPPAPCA- 648
C +C +P + EY+ D CR C C G C C C
Sbjct: 323 CDVFEC---VNDTKPACVF-NNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCER 378
Query: 649 -HPRQGPCCPSCD----------GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPK 697
+ +G CCP C+ GC G A G+R+ C C C G C
Sbjct: 379 YYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWREDD--CTFCQCVNGERHCVAT 436
Query: 698 ACAPALC-PFPARGDCCPDCD----------GCEYLGESYLSNQE----FPDPREPCNLC 742
C P G+CCP C+ C L L+ ++ F C C
Sbjct: 437 VCGQTCTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTC 496
Query: 743 TCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLC 802
C+ C R GC+ C + +T A C +C
Sbjct: 497 QCINTEELCSERK---QGCT-------------LNCPFGFLTDAQN----------CEIC 530
Query: 803 TCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRC 862
C R + K C P +C +CP+ G C+ CRC
Sbjct: 531 EC-----RPRPKKCRPIICDK------YCPLGLLKNKHG---------------CDICRC 564
Query: 863 QAGQVSCVRLQCPPL-PCKLQVTERGSCCPRCRGCLAH--------------GEEHPEGS 907
+ C L C + P Q G +CR A G H
Sbjct: 565 K----KCPELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEE 620
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQC-ISSCAQPRQGPHDCCPQCSD------------- 953
W C C C G CA I C + +C P P CCP C+D
Sbjct: 621 SW---HDGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPS 677
Query: 954 -CEHEGRKY-EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPG 1011
C G +Y GE++ D C C C + C CP L+ PS+
Sbjct: 678 ICHAPGGEYFVEGETWN--IDSCTQCTCHSG-----RVLCETEVCPPLLCQNPSRT---- 726
Query: 1012 PQHCCPTCAE-----ALSNCS---------EG--LLGSELAPPDPCYTCQCQDLTWLCIH 1055
CCP C + +LS + EG L +E PD C +C C D C
Sbjct: 727 QDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFS 786
Query: 1056 QACPELSC--PLSERHTPPGSCCPVCRAPTQS----CVHQGREVASGERWTVDTCTSCSC 1109
++CP +SC P+ + G CCP C T C G+ A ERW +D+CT C C
Sbjct: 787 ESCPSVSCERPVLRK----GQCCPYCIEDTIPKKVVCHFSGKAYADEERWDLDSCTHCYC 842
Query: 1110 MAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC----LPRPAS 1149
+ G C + C PL C P GSCCP C +P P +
Sbjct: 843 LQGQTLCSTVSCPPLPC---VEPINVEGSCCPMCPEMYVPEPTN 883
Score = 156 bits (394), Expect = 2e-37
Identities = 213/881 (24%), Positives = 275/881 (31%), Gaps = 251/881 (28%)
Query: 403 CPPAPCQHPTQPPGA-------CCPSC--------------------------------D 423
C + C+ P PG+ CC +C D
Sbjct: 40 CDESKCEEPRNCPGSIVQGVCGCCYTCASQRNESCGGTFGIYGTCDRGLRCVIRPPLNGD 99
Query: 424 SCTYHSQVYANGQNFTDAD----SPCH-----ACHCQDGTVTCSLVDCPPTTCARPQSGP 474
S T + +N+TD PC+ C+ +G C+ + TC+ P P
Sbjct: 100 SLTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTI----RTCSNPFEFP 155
Query: 475 G-------------------------QCCPRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
Q PRCP E+ V ++G + P EC
Sbjct: 156 SQDMCLSALKRIEEEKPDCSKARCEVQFSPRCP----EDSVLIEGYA------PPGECCP 205
Query: 510 QEGHAHCQPRPCPRAPC-----------AHPLPGTCCP-NDCS---GCAFGGKEYPSGAD 554
C P C R C A PG CC +C G E P
Sbjct: 206 LPSRCVCNPAGCLRKVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQQ 265
Query: 555 FPHPSDP------------CRL---CRCLSGNVQCLARRCVPLPCPEPVL----LPGECC 595
P D C L C CLSG C C P V PG+CC
Sbjct: 266 TACPPDSYETQVRLTADGCCTLPTRCECLSG--LCGFPVCEVGSTPRIVSRGDGTPGKCC 323
Query: 596 P--QCPAPAGCPRPGAAHARHQEYFSPP---GDPCRRCLCLDGSVSCQRLPCPPAPCA-- 648
+C +P A + EY+ D CR C C G C C C
Sbjct: 324 DVFEC---VNDTKP-ACVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERY 379
Query: 649 HPRQGPCCPSCD----------GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKA 698
+ +G CCP C+ GC G A G+R+ C C C G C
Sbjct: 380 YVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWREDD--CTFCQCVNGERHCVATV 437
Query: 699 CAPALC-PFPARGDCCPDCD----------GCEYLGESYLSNQE----FPDPREPCNLCT 743
C P G+CCP C+ C L L+ ++ F C C
Sbjct: 438 CGQTCTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQ 497
Query: 744 CLGGFVTCGRRP--CEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTC-- 799
C+ C R C C + C C+ CR + P D C
Sbjct: 498 CINTEELCSERKQGC-TLNCPFGFLTDAQNCEICE-CR-----PRPKKCRPIICDKYCPL 550
Query: 800 SLCTCQEGSMRCQKKPCPPALCPHPSP-----GPCFCPVCH---------------SCLS 839
L + G C+ K CP C P C +C +CL+
Sbjct: 551 GLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLT 610
Query: 840 -QGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRG--- 895
G H++ E + C C C G+ C + CP C G CCP C
Sbjct: 611 VDGHHHKNEESWH---DGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFV 667
Query: 896 -----------CLAHGEEH-PEGSRWVPPDSACSSCVCHEGVVTCARIQCIS-SCAQPRQ 942
C A G E+ EG W +C+ C CH G V C C C P +
Sbjct: 668 VQKPELSTPSICHAPGGEYFVEGETW--NIDSCTQCTCHSGRVLCETEVCPPLLCQNPSR 725
Query: 943 GPHDCCPQCSD----------------CEH-EGRKYEPGESFQPGADPCEVCICEPQPEG 985
CCPQC+D C++ EG + ES++P D C CIC
Sbjct: 726 TQDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKP--DVCTSCICIDS--- 780
Query: 986 PPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAE-------ALSNCSEGLLGSELAPP 1038
+ C CPS V C +L G CCP C E + E
Sbjct: 781 --VISCFSESCPS-VSC-ERPVLRKG--QCCPYCIEDTIPKKVVCHFSGKAYADEERWDL 834
Query: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVC 1079
D C C C LC +CP L C E GSCCP+C
Sbjct: 835 DSCTHCYCLQGQTLCSTVSCPPLPC--VEPINVEGSCCPMC 873
Score = 125 bits (314), Expect = 3e-28
Identities = 91/361 (25%), Positives = 121/361 (33%), Gaps = 82/361 (22%)
Query: 79 TRVRQLESCECHPASPQC------------------------------WGLGRAWPEGAR 108
T + E CEC P +C + P G +
Sbjct: 522 TDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQ 581
Query: 109 WEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQC 168
+ C C C++ +A GP C + +G + N E++ D C C CL G C
Sbjct: 582 QDSHGCLICKCREASASAGPPILSGTC--LTVDGHHHKNEESWH-DGCRECYCLNGREMC 638
Query: 169 QGPSCSELNCLESCTPPGECCP-----------------ICCTEGGSHWEHGQEWTTPGD 211
+C C PG+CCP IC GG ++ G+ W D
Sbjct: 639 ALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNI--D 696
Query: 212 PCRICRCLEGHIQCRQRECAS-LCPYPARPLPGTCCPVC-DGCFLNGREHRSGEP----- 264
C C C G + C C LC P+R +CCP C D F + P
Sbjct: 697 SCTQCTCHSGRVLCETEVCPPLLCQNPSR-TQDSCCPQCTDQPFRPSLSRNNSVPNYCKN 755
Query: 265 ----------VGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDG----- 309
D C+ C C + + C CP V C P GQCCP C
Sbjct: 756 DEGDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPK 815
Query: 310 ---CEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGR-QLCPA 365
C + G Y +E + L C C C G+ C CP PC P + CP
Sbjct: 816 KVVCHFSGKAYADEERWDLDS---CTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPM 872
Query: 366 C 366
C
Sbjct: 873 C 873
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 198 bits (504), Expect = 3e-50
Identities = 140/416 (33%), Positives = 189/416 (45%), Gaps = 40/416 (9%)
Query: 1082 PTQSCVHQGREVASGER-WTVDTCT-SCSCMA--GTVRCQSQRCSPLS-CGPDKAPALSP 1136
P C +G+ + GE W CT C C+ + CQ CSP C P
Sbjct: 256 PANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPK------- 308
Query: 1137 GSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTND 1192
G ++C+ FG+PHY TFDG L HFQGSC+Y+LA+ C FSV N+
Sbjct: 309 GKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNE 368
Query: 1193 DRGRSGVAWTQEVAVLLGDMAVRLLQD--GAVTVDGHPVALPF-LQEPLLYVELRGHTVI 1249
R S V+W +E++V + + + + G V V+ +LP L + + G +
Sbjct: 369 HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTA 428
Query: 1250 LHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGN 1309
+ GL V +DGQ +SVPGSY TCGLCGN+N DD P+G S G
Sbjct: 429 VETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGE 488
Query: 1310 SWQVSEGLWPGRPCSAGREVDPCRA--AGYRARREANARCGVLKSS--PFSRCHAVVPPE 1365
SW+V W C +G VD C A A + CG L + P C VV P
Sbjct: 489 SWRVYHADW---KCDSGC-VDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPT 544
Query: 1366 PFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGV-TPTWRGPTLCV--VGCPLER 1422
F +CVYDLC+ + LC A++AYA C+ G+ WR T CV V CP
Sbjct: 545 AFVHSCVYDLCSVRDNGT---LLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFS 601
Query: 1423 GFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
+ C CP TC + + +C PC GC+C G V + C+P C
Sbjct: 602 H--YSVCTSSCPDTCSDL-----TASRNCATPCTEGCECNQGFVLSTSQCVPLHKC 650
Score = 164 bits (414), Expect = 8e-40
Identities = 139/463 (30%), Positives = 201/463 (43%), Gaps = 51/463 (11%)
Query: 1039 DPCYTCQ--CQDLTW--LCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVA 1094
+ C TC C+ LT +C+ +C E C E + GS C V R+ C +G ++A
Sbjct: 991 EECITCTETCETLTLGPICV-DSCSE-GCQCDEGYALLGSQC-VTRSEC-GCNFEGHQLA 1046
Query: 1095 SGERWTVDTCTSCSCM-AGT---VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASC 1150
+ E + VD C +GT V C++ C D + G ASC
Sbjct: 1047 TNETFWVDLDCQIFCYCSGTDNRVHCETIPCK------DDEYCMEEGGLYYCQARTDASC 1100
Query: 1151 MAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD---------FSVHVTNDDRGRSGVAW 1201
+ G HY TFDG FQ SC +L C +G F V N+DR S W
Sbjct: 1101 IVSGYGHYLTFDGFPFDFQTSCPLIL---CTTGSRPSSDSFPKFVVTAKNEDRDPSLALW 1157
Query: 1202 TQEVAVLLG--DMAVRLLQDGAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQV 1258
++V V + + + V V+ + LP L + + + G V++ GL+V
Sbjct: 1158 VKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKV 1217
Query: 1259 LWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLW 1318
++D ++ + ++VP S Q T GLCG +NG DDL+ P GLL S FG SW +
Sbjct: 1218 VYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF- 1276
Query: 1319 PGRPCSAGREVDPCRAAGYRARREANARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLC 1376
C G A + C ++ +++ FS+CH+ V P F+ C++D C
Sbjct: 1277 ----CQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSC 1332
Query: 1377 ACGPGSSADACLCDALEAYASHCRQAGVTPT-WRGPTLCVVGCPLERGFVFDECGPPCPR 1435
G A C L+ YAS C+ G+T T WR T C V CP ++ C C
Sbjct: 1333 IDG---GAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSH--YESCVSVCQP 1387
Query: 1436 TCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
C L + C CV GC C AG V + CI P +C
Sbjct: 1388 RC-----AAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSC 1425
Score = 132 bits (333), Expect = 2e-30
Identities = 133/504 (26%), Positives = 193/504 (38%), Gaps = 79/504 (15%)
Query: 996 CPSLVGCPPSQLLPPGPQHCCPTCAE--ALSNCSEGLLGSELAPPDPCYT-CQCQDLTWL 1052
C S V CP C TC++ A NC+ PC C+C L
Sbjct: 591 CVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCAT-----------PCTEGCECNQGFVL 639
Query: 1053 CIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER-WTVDTCT-SCSCM 1110
Q P C C G GE W CT C C
Sbjct: 640 STSQCVPLHKC---------------------GCDFDGHYYTMGEFFWATANCTVQCLCE 678
Query: 1111 AGTVRCQSQRCSPLSCGPDKAPALSPG--SCCPRCLPRPASCMAFGDPHYRTFDGRLLHF 1168
G C +CG + A+ G C P+ R C+ + TFDG F
Sbjct: 679 EGG----DVYCFNKTCGSGEVCAVEDGYQGCFPK---RETVCLLSQNQVLHTFDGASYAF 731
Query: 1169 QGSCSYVLAKDCHSGDFSVHVT-NDDRGRSGVAWTQEVAVLLGDMAVRLLQDGA--VTVD 1225
SY L K C + + N + +G AW + + +L+ D V++ GA V ++
Sbjct: 732 PSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLN 791
Query: 1226 GHPVALPFLQEP-LLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGN 1284
G V LPF L + ++ + ++ + V + + + + +Y T GLCG
Sbjct: 792 GQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGF 851
Query: 1285 FNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPG------RPCSAGREVDPCRAAGYR 1338
+N A D+ P G + A F SW E + G + C+ E+ YR
Sbjct: 852 YNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSEL----LKFYR 907
Query: 1339 ARREANARCGVL---KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAY 1395
+R +RCG++ +S F CH VV ++ C++ LC G S LCD++ Y
Sbjct: 908 SR----SRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESE---LCDSVARY 960
Query: 1396 ASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRP 1454
AS C+ A V WR C + CP F+EC C TC + + LG + CV
Sbjct: 961 ASACKNADVEVGPWRTYDFCPLECP--ENSHFEEC-ITCTETC--ETLTLGPI---CVDS 1012
Query: 1455 CVPGCQCPAGLVEHEAHCIPPEAC 1478
C GCQC G + C+ C
Sbjct: 1013 CSEGCQCDEGYALLGSQCVTRSEC 1036
Score = 111 bits (277), Expect = 6e-24
Identities = 95/370 (25%), Positives = 147/370 (39%), Gaps = 35/370 (9%)
Query: 1099 WTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CMAFGDPH 1157
W D C C V +C P C D+ AL G C S C+A G
Sbjct: 1441 WNSDCTRRCRCFRRNVI----QCDPRQCKSDEECALRNG--VRGCFSTKTSYCLAAGGGV 1494
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCHSG---DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAV 1214
+RTFDG L F +C++VL+ C F + + D + V + + +
Sbjct: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQI 1554
Query: 1215 RLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSY 1274
+ V V+G V +PF+ + +++ P +Q+ ++G + +++S+
Sbjct: 1555 LINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERL 1614
Query: 1275 QGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRA 1334
Q + CGLCGNFNG DD G + S SW+ + G+ + E+ +
Sbjct: 1615 QNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWK-TNGMQKRPLAPSCNELQFSQY 1673
Query: 1335 AG-----YRARREANARCGVLKSSP--FSRCHAVVPPEPFFAACVYDLCACGPGSSADAC 1387
A + + + + C L F C+ ++ P PF+ +C D C S
Sbjct: 1674 AAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCY----SHKKFQ 1729
Query: 1388 LCDALEAYASHCRQAGVTPT-WRGPTLCVVGCPLERGFVFDEC-GPPCP-RTCFNQHIPL 1444
LC +L AY CR G+ T W C G V D C G CP RTC +
Sbjct: 1730 LCGSLAAYGEACRSFGILSTEWIEKENC-------SGVVEDPCVGADCPNRTC---ELGN 1779
Query: 1445 GELAAHCVRP 1454
G C+ P
Sbjct: 1780 GRELCGCIEP 1789
Score = 35.8 bits (81), Expect = 0.32
Identities = 23/55 (41%), Positives = 26/55 (47%), Gaps = 7/55 (12%)
Query: 137 GCSQNGQTYGNGETFSPDA-CTT-CRCL--TGAVQCQGPSCSELNCLESCTPPGE 187
GC+ GQ GE F D CT CRCL + CQ SCS E C P G+
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSP---YEVCEPKGK 310
Score = 35.8 bits (81), Expect = 0.32
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 2/59 (3%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCL-TGAVQCQGPSC 173
C C G G LPH GC +G+ Y + F CT CRC +QC C
Sbjct: 1406 CHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQC 1464
Score = 32.3 bits (72), Expect = 3.5
Identities = 51/228 (22%), Positives = 71/228 (31%), Gaps = 45/228 (19%)
Query: 154 DACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPC 213
D CT C T A+ C LN + P EC + H + +
Sbjct: 505 DNCTQCDAATEALYFGSDYCGFLNKTDG--PLWECGTVVDPTAFVHSCVYDLCSVRDNGT 562
Query: 214 RICRCLEGH-IQCR-----------QRECASLCPYPARPLPGTCCPVC-DGCFLNGREHR 260
+C+ ++ + + C+ Q C S P+ C C D C
Sbjct: 563 LLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRN 622
Query: 261 SGEPVGSGDPCSHCRCANGSV----QCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQ 316
P G C C G V QC PL +C GC++ GH
Sbjct: 623 CATPCTEG-----CECNQGFVLSTSQCVPLH--------------KC-----GCDFDGHY 658
Query: 317 YQSQETFRLQERGLCVRCSC-QAGEVSCEEQECPVTPCALPASGRQLC 363
Y E F V+C C + G+V C + C G Q C
Sbjct: 659 YTMGEFF-WATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGC 705
Score = 32.0 bits (71), Expect = 4.6
Identities = 29/108 (26%), Positives = 37/108 (34%), Gaps = 10/108 (9%)
Query: 114 CT-ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLT---GAVQC- 168
CT C C G Q H GC +G Y GE F A T +CL G V C
Sbjct: 627 CTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCF 686
Query: 169 -----QGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGD 211
G C+ + + C P E + H G + P +
Sbjct: 687 NKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSE 734
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 189 bits (480), Expect = 2e-47
Identities = 168/613 (27%), Positives = 238/613 (38%), Gaps = 120/613 (19%)
Query: 888 SCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDC 947
+C P CR L+ G+ ++P D C+C +G +C+ +
Sbjct: 716 TCQPTCRS-LSEGDITCSVG-FIPVDG----CICPKGTFLDDTGKCVQASN--------- 760
Query: 948 CPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQL 1007
CP C H G GES D +C C L C Q P+ V P
Sbjct: 761 CP----CYHRGSMIPNGESVH---DSGAICTCTHG-----KLSCIGGQAPAPVCAAPMVF 808
Query: 1008 LPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQ--CQDLTWLCIHQAC-PELSCP 1064
C A P D CQ C L C C P CP
Sbjct: 809 FD---------CRNA-------------TPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCP 846
Query: 1065 LSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPL 1124
G C P CVH +G+ V C +C+C + RC C
Sbjct: 847 DGLVADGEGGCITAEDCP---CVHNEASYRAGQTIRVG-CNTCTCDSRMWRCTDDPCL-- 900
Query: 1125 SCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA------K 1178
A+C +GD HY TFDG+ F G C Y L K
Sbjct: 901 -----------------------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGK 937
Query: 1179 DCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPL 1238
D F V N G +G ++ + + LG ++L G V V G + QE
Sbjct: 938 DSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKL-SHGKVEVIGTDES----QEVP 992
Query: 1239 LYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
+ G +++ GL +LWD ++ + +++ ++GR CGLCGNF+ A +D
Sbjct: 993 YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSR 1052
Query: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRC 1358
++ FGNSW++S P P A DPC A +R + A +C +L F+ C
Sbjct: 1053 SVVGDVLEFGNSWKLS----PSCP-DALAPKDPCTANPFR-KSWAQKQCSILHGPTFAAC 1106
Query: 1359 HAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGC 1418
HA V P ++ ACV D CAC G + C C A+ AYA C + G+ +WR P++C + C
Sbjct: 1107 HAHVEPARYYEACVNDACACDSGGDCE-CFCTAVAAYAQACHEVGLCVSWRTPSICPLFC 1165
Query: 1419 PL-----ERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRP------CVPGCQCPAGLV- 1466
+ + + CG PC RTC N P G+ C+R C P C A +
Sbjct: 1166 DYYNPEGQCEWHYQPCGVPCLRTCRN---PRGD----CLRDVWGLEGCYPKCPPEAPIFD 1218
Query: 1467 EHEAHCIPPEACP 1479
E + C+ CP
Sbjct: 1219 EDKMQCV--ATCP 1229
Score = 158 bits (399), Expect = 4e-38
Identities = 120/376 (31%), Positives = 169/376 (44%), Gaps = 43/376 (11%)
Query: 1122 SPLSCGPDKAPALSPGSCCP--RCLP-----RPAS----CMAFGDPHYRTFDGRLLHFQG 1170
SP++ GP P L + P R +P PA C +G HY+TFDG + F G
Sbjct: 43 SPIARGPSGVP-LRGATVFPSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPG 101
Query: 1171 SCSYVLAKDCHSG--DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHP 1228
C+YV ++ C + DF++ + R + A T ++ D V L G+V V+GHP
Sbjct: 102 LCNYVFSEHCGAAYEDFNIQLR---RSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHP 158
Query: 1229 VALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGF 1288
V LPF Q +L + +T + A+ GL ++W+ + + + Y +TCGLCG+FNG
Sbjct: 159 VLLPFSQSGVLIQQSSSYTKV-EARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGM 217
Query: 1289 -AQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCR-AAGYRARREANAR 1346
+L L P E FGN ++ + P C P + G+ E
Sbjct: 218 PVVSELLSHNTKLTPME--FGNLQKMDD---PTEQCQDPVPEPPRNCSTGFGICEE---- 268
Query: 1347 CGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTP 1406
+L FS C A+V + AC DLC C + +C+C L Y+ C AG P
Sbjct: 269 --LLHGQLFSGCVALVDVGSYLEACRQDLCFC-EDTDLLSCVCHTLAEYSRQCTHAGGLP 325
Query: 1407 -TWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGL 1465
WRGP C CP + EC PC TC NQ E + C CV GC CP G
Sbjct: 326 QDWRGPDFCPQKCP--NNMQYHECRSPCADTCSNQ-----EHSRACEDHCVAGCFCPEGT 378
Query: 1466 VEH---EAHCIPPEAC 1478
V + C+P C
Sbjct: 379 VLDDIGQTGCVPVSKC 394
Score = 141 bits (356), Expect = 4e-33
Identities = 134/521 (25%), Positives = 191/521 (36%), Gaps = 82/521 (15%)
Query: 977 CICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALS--NCSEGLLGSE 1034
C+C E + RQC G P GP C C + C
Sbjct: 306 CVCHTLAE-------YSRQCTHAGGLPQDWR---GPDFCPQKCPNNMQYHECRS------ 349
Query: 1035 LAPPDPCY-TCQCQDLTWLCIHQACPELSCPLSERHTPPGS--CCPVCRAPTQSCVHQGR 1091
PC TC Q+ + C CP G C PV + +CV+ G
Sbjct: 350 -----PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKC---ACVYNGA 401
Query: 1092 EVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCM 1151
A G ++ D CT+C+C G CQ C P +C
Sbjct: 402 AYAPGATYSTD-CTNCTCSGGRWSCQEVPC-------------------------PGTCS 435
Query: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGD 1211
G H+ TFDG+ G CSYVL K C S F+V G + + L D
Sbjct: 436 VLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLD 495
Query: 1212 ---MAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD--GQSQV 1266
V + G V ++ LP + +I GLQ+ Q+
Sbjct: 496 GVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQL 555
Query: 1267 EVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAG 1326
+ + +G+TCGLCGNFN DD + G++ + AAF N+++ P
Sbjct: 556 FMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAAC----PNIRN 611
Query: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCACGPGSSA 1384
DPC + + A C L + PF RCHA V P +++ C++D C C +
Sbjct: 612 SFEDPC-SLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC---ERS 667
Query: 1385 DACLCDALEAYASHCRQAGV-TPTWRGP--TLCVVGCPLERGFVF--DECGPPCPRTCFN 1439
+ CLC AL +Y C GV WR T + CP + + C P C
Sbjct: 668 EDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTC------ 721
Query: 1440 QHIPLGELAAHCVRPCVPGCQCPAG-LVEHEAHCIPPEACP 1479
+ + G++ V GC CP G ++ C+ CP
Sbjct: 722 RSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCP 762
Score = 48.1 bits (113), Expect = 6e-05
Identities = 108/500 (21%), Positives = 143/500 (28%), Gaps = 115/500 (23%)
Query: 245 CCPVCD-GCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQC 303
C PV C NG + G + C++C C+ G C+ +PCP C G G
Sbjct: 388 CVPVSKCACVYNGAAYAPGATYSTD--CTNCTCSGGRWSCQEVPCPGT-CSVLG---GAH 441
Query: 304 CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVT-------PCALP 356
DG +Y H S L C A V E + C +T L
Sbjct: 442 FSTFDGKQYTVHGDCSYV--------LTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLS 493
Query: 357 ASGRQLCPACELDGEEFAEGV--------------------------------------- 377
G Q + GE F +
Sbjct: 494 LDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTM 553
Query: 378 ----QWEPD--GRPCTAC-----VCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC---- 422
Q P G+ C C + D V+ A T A CP+
Sbjct: 554 QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSF 613
Query: 423 -DSC--TYHSQVYANG--QNFTDADSPCHACHC--QDGTV-------TCSLVDCPPTTCA 468
D C + ++ YA TDAD P CH + GT TC+ CA
Sbjct: 614 EDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCA 673
Query: 469 RPQSGPGQCCP--------RCPDCILEEEVFVDGESFSHPRDPCQ-ECR-CQEGHAHCQP 518
S C R C ++ + CQ CR EG C
Sbjct: 674 ALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSV 733
Query: 519 RPCPRAPCAHPL------PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNV 572
P C P G C C G P+G D +C C G +
Sbjct: 734 GFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV---HDSGAICTCTHGKL 790
Query: 573 QCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSP---PGDPCRRCL 629
C+ + C P++ +C P G + H +SP PG C L
Sbjct: 791 SCIGGQAPAPVCAAPMVF-FDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGL 849
Query: 630 CLDGSVSCQRLPCPPAPCAH 649
DG C + PC H
Sbjct: 850 VADGEGGC--ITAEDCPCVH 867
Score = 48.1 bits (113), Expect = 6e-05
Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 49/220 (22%)
Query: 97 WGLGRAWPEGARWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPD 154
W L + P+ A D CTA + A C H P C + + E D
Sbjct: 1065 WKLSPSCPD-ALAPKDPCTANPFRKSWAQKQCSI-LHGPTFAACHAHVEPARYYEACVND 1122
Query: 155 ACTT-----CRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCT----EGGSHWEHGQE 205
AC C C AV +C E+ S P CP+ C EG W +
Sbjct: 1123 ACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS-ICPLFCDYYNPEGQCEWHY--- 1178
Query: 206 WTTPGDPC-RICR-----CL------EG-HIQCR---------QRECASLCPYPARPLPG 243
G PC R CR CL EG + +C + +C + CP P PLP
Sbjct: 1179 -QPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTP--PLPP 1235
Query: 244 TCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQC 283
C ++G+ +R G V S C C C V+C
Sbjct: 1236 RC-------HVHGKSYRPGAVVPSDKNCQSCLCTERGVEC 1268
Score = 46.6 bits (109), Expect = 2e-04
Identities = 57/236 (24%), Positives = 72/236 (30%), Gaps = 66/236 (27%)
Query: 404 PPAPCQHPT-QPPGACCPSCDSCT--YHSQVYANGQNFTDADSPCHACH-----CQDGTV 455
P CQ P +PP C C H Q+++ D S AC C+D
Sbjct: 244 PTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED--- 300
Query: 456 TCSLVDCPPTTCAR-----------PQS--GPGQCCPRCPDCILEEEVFVDGESFSHPRD 502
L+ C T A PQ GP C +CP+ + E R
Sbjct: 301 -TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHEC----------RS 349
Query: 503 PCQE-CRCQEGHAHCQPRP-----CPRAPCAHPLPGT-CCPNDCSGCAFGGKEYPSGADF 555
PC + C QE C+ CP + T C P C + G Y GA +
Sbjct: 350 PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 556 PHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAH 611
S C C C G C + P P C G AH
Sbjct: 410 ---STDCTNCTCSGGRWSC---------------------QEVPCPGTCSVLGGAH 441
Score = 45.4 bits (106), Expect = 4e-04
Identities = 36/113 (31%), Positives = 47/113 (41%), Gaps = 22/113 (19%)
Query: 105 EGARWEPDACTA-CVCQDGAA--HCGPQAHLPHCR-GCSQNGQTYGNGETFSPDACTTCR 160
E +R D C A C C +G G +P + C NG Y G T+S D CT C
Sbjct: 359 EHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-CTNCT 417
Query: 161 CLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWE--HGQEWTTPGD 211
C G CQ C PG C + GG+H+ G+++T GD
Sbjct: 418 CSGGRWSCQEVPC-----------PGTCSVL----GGAHFSTFDGKQYTVHGD 455
Score = 45.1 bits (105), Expect = 5e-04
Identities = 61/245 (24%), Positives = 80/245 (32%), Gaps = 51/245 (20%)
Query: 415 PGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQS-- 472
P CP S TYH V + C + +G +TCS+ P C P+
Sbjct: 700 PMTTCPK--SMTYHYHV-------STCQPTCRSL--SEGDITCSVGFIPVDGCICPKGTF 748
Query: 473 --GPGQC--CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAH 528
G+C CP C + +GES D C C G C P CA
Sbjct: 749 LDDTGKCVQASNCP-CYHRGSMIPNGESV---HDSGAICTCTHGKLSCIGGQAPAPVCAA 804
Query: 529 PLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVP-LPCPEP 587
P+ C N G G + + C L ++ C + +CVP CP+
Sbjct: 805 PMVFFDCRNATPGDTGAGCQ--------------KSCHTL--DMTCYSPQCVPGCVCPDG 848
Query: 588 VLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDP----CRRCLCLDGSVSCQRLPCP 643
++ GE GC H E G C C C C PC
Sbjct: 849 LVADGE--------GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC- 899
Query: 644 PAPCA 648
A CA
Sbjct: 900 LATCA 904
Score = 45.1 bits (105), Expect = 5e-04
Identities = 72/320 (22%), Positives = 101/320 (31%), Gaps = 82/320 (25%)
Query: 849 EFEGPAGSCEWCRCQAGQVSCVRL-QCPPLPCKLQVTERGSCCPRCRG------------ 895
++ P G CEW G V C+R + P C V C P+C
Sbjct: 1166 DYYNPEGQCEWHYQPCG-VPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQC 1224
Query: 896 ------------CLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQG 943
C HG+ + G+ VP D C SC+C E V C +C
Sbjct: 1225 VATCPTPPLPPRCHVHGKSYRPGAV-VPSDKNCQSCLCTERGVECT--YKAEACV----- 1276
Query: 944 PHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRC------HRRQCP 997
C + G+++ PG+ D CI S RC RR P
Sbjct: 1277 ----------CTYNGQRFHPGDVIYHTTDGTGGCI---------SARCGANGTIERRVYP 1317
Query: 998 SLVGCPPSQLLPPGPQHCC--PTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
C P+ +PP P + S G + PP W
Sbjct: 1318 ----CSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSS---------AWPTTA 1364
Query: 1056 QACPELSCPLSERHTPPGSCCPVCR-APTQSCVHQGREVASGERWTVDTCTSCSCMAGTV 1114
P P + PP C C +P GR SG+ T++ + G
Sbjct: 1365 GTSPRTRLPTASASLPP-VCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRA----HGYR 1419
Query: 1115 RCQSQRCSPLSCGPDKAPAL 1134
C+S R + C + AP +
Sbjct: 1420 VCESPR--SVECRAEDAPGV 1437
Score = 43.9 bits (102), Expect = 0.001
Identities = 68/276 (24%), Positives = 92/276 (33%), Gaps = 61/276 (22%)
Query: 559 SDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAP-AGCPRPGAAHARHQEY 617
S+ C LC LS V A + V L G C P CP+ H Y
Sbjct: 667 SEDC-LCAALSSYVHACAAKGVQLG--------GWRDGVCTKPMTTCPKSMTYH-----Y 712
Query: 618 FSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR------QGPCCPSCD-GCLYQGKEFA 670
P R L +G ++C P C P+ G C + + C ++G
Sbjct: 713 HVSTCQPTCRSLS-EGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIP 771
Query: 671 SGERFPSPTAACHLCLCWEGSVSC------EPKACAPAL---CPFPARGDCCPDCD-GCE 720
+GE A +C C G +SC P AP + C GD C C
Sbjct: 772 NGESVHDSGA---ICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCH 828
Query: 721 YLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRY 780
L + S Q P C C G V G C + CP C +
Sbjct: 829 TLDMTCYSPQCVPG-------CVCPDGLVADGEGGCI----------TAEDCP----CVH 867
Query: 781 HGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPC 816
+ + +G+T+ C+ CTC RC PC
Sbjct: 868 NEASYRAGQTIR----VGCNTCTCDSRMWRCTDDPC 899
Score = 43.1 bits (100), Expect = 0.002
Identities = 48/204 (23%), Positives = 70/204 (34%), Gaps = 38/204 (18%)
Query: 747 GFVTCGRRPCEPPGCSHP----LIPSGHC-----CPTCQGCRYHGVTTASGETLPDPLDP 797
G +TC GC P L +G C CP C + G +GE++ D
Sbjct: 727 GDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCP----CYHRGSMIPNGESVHD---- 778
Query: 798 TCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSC 857
+ ++CTC G + C P +C P V C R G+ G SC
Sbjct: 779 SGAICTCTHGKLSCIGGQAPAPVCAAPM-------VFFDC----RNATPGDTGAGCQKSC 827
Query: 858 EWCRCQAGQVSCVRLQCPP---LPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDS 914
++C QC P P L G C H E + +
Sbjct: 828 HTL-----DMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI--RV 880
Query: 915 ACSSCVCHEGVVTCARIQCISSCA 938
C++C C + C C+++CA
Sbjct: 881 GCNTCTCDSRMWRCTDDPCLATCA 904
Score = 41.2 bits (95), Expect = 0.008
Identities = 53/204 (25%), Positives = 72/204 (35%), Gaps = 33/204 (16%)
Query: 632 DGSVSCQR-LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACH--LCLCW 688
D + CQ +P PP C+ G C G L+ G + S AC LC C
Sbjct: 243 DPTEQCQDPVPEPPRNCS-TGFGICEELLHGQLFSG--CVALVDVGSYLEACRQDLCFCE 299
Query: 689 EGSV-SCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGG 747
+ + SC A G D G ++ + +N ++ + R PC
Sbjct: 300 DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCA------- 352
Query: 748 FVTCGR----RPCEPPGCSHPLIPSGH---------CCPTCQ-GCRYHGVTTASGETLPD 793
TC R CE + P G C P + C Y+G A G T
Sbjct: 353 -DTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY-- 409
Query: 794 PLDPTCSLCTCQEGSMRCQKKPCP 817
C+ CTC G CQ+ PCP
Sbjct: 410 --STDCTNCTCSGGRWSCQEVPCP 431
Score = 41.2 bits (95), Expect = 0.008
Identities = 47/179 (26%), Positives = 63/179 (35%), Gaps = 37/179 (20%)
Query: 389 CVCQDGVPKC--GAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH 446
C G+P+ G CP C + Q P D+C+ N ++ + C
Sbjct: 318 CTHAGGLPQDWRGPDFCPQK-CPNNMQYHECRSPCADTCS-------NQEHSRACEDHCV 369
Query: 447 A-CHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQ 505
A C C +GTV L D T C P C C+ + G ++S C
Sbjct: 370 AGCFCPEGTV---LDDIGQTGCV-----PVSKCA----CVYNGAAYAPGATYS---TDCT 414
Query: 506 ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP-NDCSGCAFGGKEYPSGADFPHP-SDPC 562
C C G CQ PC PGTC F GK+Y D + + PC
Sbjct: 415 NCTCSGGRWSCQEVPC---------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPC 464
Score = 38.5 bits (88), Expect = 0.049
Identities = 33/124 (26%), Positives = 50/124 (40%), Gaps = 32/124 (25%)
Query: 175 ELNCLESC-TPPGECCPICCTEGGSHWEHGQEWTTPGDP-CRICRCLEGHIQCRQRECAS 232
++ C+ +C TPP P C G + G P D C+ C C E ++C + A
Sbjct: 1221 KMQCVATCPTPP---LPPRCHVHGKSYRPGA--VVPSDKNCQSCLCTERGVECTYKAEAC 1275
Query: 233 LCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-----GSGDPCSHCRC-ANGSVQCEPL 286
+C Y NG+ G+ + G+G C RC ANG+++
Sbjct: 1276 VCTY------------------NGQRFHPGDVIYHTTDGTGG-CISARCGANGTIERRVY 1316
Query: 287 PCPP 290
PC P
Sbjct: 1317 PCSP 1320
Score = 38.1 bits (87), Expect = 0.065
Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 11/113 (9%)
Query: 536 PNDCSGCAFGGKEYPSGADFPHPSDPCR-LCRCLSGNVQCLARRCVPLPCPEPVLLPG-- 592
P D G F ++ P+ + PC C + C CPE +L
Sbjct: 325 PQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIG 384
Query: 593 --ECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 643
C P + C GAA+A Y + C C C G SCQ +PCP
Sbjct: 385 QTGCVPV--SKCACVYNGAAYAPGATYSTD----CTNCTCSGGRWSCQEVPCP 431
Score = 37.0 bits (84), Expect = 0.14
Identities = 41/147 (27%), Positives = 48/147 (32%), Gaps = 37/147 (25%)
Query: 274 CRC---ANGSVQCEPLPCPPVPCRHPGKIPGQC----------CPVCDGCEYQGHQYQSQ 320
C C A S QC P R P P +C P D C Q H
Sbjct: 306 CVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHS---- 361
Query: 321 ETFRLQERGLCVRCSCQAGEVSCE--EQEC-PVTPCALPASGRQLCPACELDGEEFAEGV 377
R E C C G V + + C PV+ CA C +G +A G
Sbjct: 362 ---RACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA-----------CVYNGAAYAPGA 407
Query: 378 QWEPDGRPCTACVCQDGVPKCGAVLCP 404
+ D CT C C G C V CP
Sbjct: 408 TYSTD---CTNCTCSGGRWSCQEVPCP 431
Score = 35.8 bits (81), Expect = 0.32
Identities = 105/483 (21%), Positives = 133/483 (27%), Gaps = 100/483 (20%)
Query: 681 ACH---LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPRE 737
ACH LC+ W P++CP C+Y +
Sbjct: 1145 ACHEVGLCVSWR----------TPSICPL-----------FCDYYNPEGQCEWHYQPCGV 1183
Query: 738 PCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSG--------HCCPTCQG------CRYHGV 783
PC L TC C R GC P C TC C HG
Sbjct: 1184 PC-LRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGK 1242
Query: 784 TTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGRE 843
+ G +P D C C C E + C K C C G+
Sbjct: 1243 SYRPGAVVPS--DKNCQSCLCTERGVECTYK----------------AEAC-VCTYNGQR 1283
Query: 844 HQDGE---EFEGPAGSCEWCRCQA-GQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAH 899
G+ G C RC A G + C P T S P
Sbjct: 1284 FHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHT 1343
Query: 900 GEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGR 959
P + PP SA + G R+ S+ P G D GR
Sbjct: 1344 PSNGPSSAHTGPPSSAWPTTA---GTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGR 1400
Query: 960 KYEPGE---SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCC 1016
+ G+ A VC E P S+ C P + P + L Q C
Sbjct: 1401 GTDSGDFDTLENLRAHGYRVC------ESPRSVECRAEDAPGV----PLRALGQRVQ-CS 1449
Query: 1017 PTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
P N + CY Q + Q C L+C S + P
Sbjct: 1450 PDVGLTCRNREQA--------SGLCYNYQIR-------VQCCTPLACSTS---SSPAQTT 1491
Query: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMA-GTVRCQSQRCSPLSCGPDKAPALS 1135
P + T G S TV T+ + A GT + S S P PA S
Sbjct: 1492 PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPS--PPPVPATS 1549
Query: 1136 PGS 1138
S
Sbjct: 1550 TSS 1552
Score = 33.9 bits (76), Expect = 1.2
Identities = 59/284 (20%), Positives = 81/284 (28%), Gaps = 93/284 (32%)
Query: 479 PRCPDCILEEEVFVDGESFSHPRDPC-----------QECRCQEG------HAHCQP--- 518
P CPD + P+DPC ++C G HAH +P
Sbjct: 1069 PSCPDALA-------------PKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARY 1115
Query: 519 -RPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSG--------------ADFPHPSDPCR 563
C CA G C + A+ + G D+ +P C
Sbjct: 1116 YEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCE 1175
Query: 564 ----------LCRCLSGNVQCLA-----RRCVPLPCPEPVLLPGE---CCPQCPAPAGCP 605
L C + CL C P PE + + C CP P P
Sbjct: 1176 WHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTP---P 1232
Query: 606 RPGAAHARHQEY----FSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDG 661
P H + Y P C+ CLC + V C + C
Sbjct: 1233 LPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVEC------------TYKAEACV---- 1276
Query: 662 CLYQGKEFASGE---RFPSPTAACHLCLCW-EGSVSCEPKACAP 701
C Y G+ F G+ T C C G++ C+P
Sbjct: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSP 1320
Score = 33.5 bits (75), Expect = 1.6
Identities = 30/127 (23%), Positives = 46/127 (36%), Gaps = 28/127 (22%)
Query: 818 PALCPHPSPG-----PCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRL 872
P CP P C P +C +Q EH E AG C C G V
Sbjct: 331 PDFCPQKCPNNMQYHECRSPCADTCSNQ--EHSRACEDHCVAG----CFCPEGTV----- 379
Query: 873 QCPPLPCKLQVTERGSCCPRCR-GCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARI 931
L + C P + C+ +G + G+ + + C++C C G +C +
Sbjct: 380 --------LDDIGQTGCVPVSKCACVYNGAAYAPGATY---STDCTNCTCSGGRWSCQEV 428
Query: 932 QCISSCA 938
C +C+
Sbjct: 429 PCPGTCS 435
Score = 32.0 bits (71), Expect = 4.6
Identities = 40/154 (25%), Positives = 52/154 (33%), Gaps = 25/154 (16%)
Query: 84 LESCECHPA---SPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQ 140
L SC CH S QC G P+ R PD C C CR S
Sbjct: 303 LLSCVCHTLAEYSRQCTHAG-GLPQDWRG-PDFCPQ--------KCPNNMQYHECR--SP 350
Query: 141 NGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHW 200
T N E AC C+ G +G ++ C P +C C G+ +
Sbjct: 351 CADTCSNQE--HSRACED-HCVAGCFCPEGTVLDDIG-QTGCVPVSKCA---CVYNGAAY 403
Query: 201 EHGQEWTTPGDPCRICRCLEGHIQCRQRECASLC 234
G ++T C C C G C++ C C
Sbjct: 404 APGATYSTD---CTNCTCSGGRWSCQEVPCPGTC 434
Score = 31.2 bits (69), Expect = 7.9
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 41/192 (21%)
Query: 270 PCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERG 329
P C C G+ + C + CP C ++G + E+ + + G
Sbjct: 737 PVDGCICPKGTFLDDTGKC----------VQASNCP----CYHRGSMIPNGES--VHDSG 780
Query: 330 LCVRCSCQAGEVSCEEQECPVTPCALP--------ASGRQLCPACELDGEEFAEGVQWEP 381
C+C G++SC + P CA P A+ C+ + + P
Sbjct: 781 AI--CTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTL-DMTCYSP 837
Query: 382 DGRPCTACVCQDGV---PKCGAVLCPPAPCQHPTQPPGA---CCPSCDSCTYHSQVYANG 435
P CVC DG+ + G + PC H A C++CT S+++
Sbjct: 838 QCVP--GCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMW--- 892
Query: 436 QNFTDADSPCHA 447
D PC A
Sbjct: 893 ---RCTDDPCLA 901
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 189 bits (479), Expect = 2e-47
Identities = 131/461 (28%), Positives = 197/461 (42%), Gaps = 59/461 (12%)
Query: 1046 CQDLTWLCIHQACPE-LSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTC 1104
CQ L H C CP G C P CVH +SG + VD C
Sbjct: 784 CQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP---CVHNNDLYSSGAKIKVD-C 839
Query: 1105 TSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGR 1164
+C+C G C C +C +G HY TFDG+
Sbjct: 840 NTCTCKRGRWVCTQAVCH-------------------------GTCSIYGSGHYITFDGK 874
Query: 1165 LLHFQGSCSYVLAKD-----CHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD 1219
F G CSYV +D G FS+ N G +GV ++ + + +G ++L
Sbjct: 875 YYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDK 934
Query: 1220 GAVTV---DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQG 1276
V + +GH VA + G +++ + G+ V+WD ++ V + + SY+G
Sbjct: 935 HRVVIQRDEGHHVAYTTREV--------GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKG 986
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAG 1336
CGLCGNF+ + +D + +++ SE FGNSW+ + P P +PC
Sbjct: 987 TVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA----PTCP-DVSTNPEPCSLNP 1041
Query: 1337 YRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYA 1396
+R R A +C +LKSS FS CH+ V P+PF+ ACV+D C+C G + C C A+ +YA
Sbjct: 1042 HR-RSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCE-CFCSAVASYA 1099
Query: 1397 SHCRQAGVTPTWRGPTLCVVGC-----PLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
C + G WR P LC + C P E + ++ CG TC + ++
Sbjct: 1100 QECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSY 1159
Query: 1452 VRPCVPGCQCPAGLVEHE-AHCIPPEACPQVLLTGDQPLGA 1491
+ C P C + E + C+ + C + P GA
Sbjct: 1160 LEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1200
Score = 157 bits (397), Expect = 7e-38
Identities = 159/597 (26%), Positives = 226/597 (37%), Gaps = 109/597 (18%)
Query: 943 GPHDCCPQCSDCEHEGRKYEPGE--SFQPGADPCEVCICEPQPEGPPSLRCHRRQC---- 996
G ++ S+ +G + P E + Q P VC + P S HR +C
Sbjct: 170 GDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLL 229
Query: 997 ---------------PSLVGCPPSQLLPPGPQHC-CPTCAEALSNCSE--GLLGS----- 1033
P L C + PG C C T AE CS G G+
Sbjct: 230 TAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTAT 289
Query: 1034 -----------ELAPPDPCY-TCQCQDLTWLCIHQACPELSCPLSERHTPPGS--CCPVC 1079
L PC TC +++ LC CP + G C PV
Sbjct: 290 LCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVS 349
Query: 1080 RAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSC 1139
+ C G G+ T D C C C AG C+
Sbjct: 350 QC---HCRLHGHLYTPGQEITND-CEQCVCNAGRWVCKD--------------------- 384
Query: 1140 CPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGV 1199
LP P +C G H TFDG+ F G C YVLAK H+ +++ G +
Sbjct: 385 ----LPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDK 440
Query: 1200 AWTQEVAVLLGDMAVRLL---QDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPG- 1255
+ VLL D ++ DG+V ++ V LP + + +++ G
Sbjct: 441 QTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGV 500
Query: 1256 -LQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVS 1314
LQV Q+ V++ + QG+ GLCGNFNG DD + GL+ + A F N+W+
Sbjct: 501 RLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQ 560
Query: 1315 EGL-----WPGRPCSAGREVDPCRAAGYRARREANARCGVLK--SSPFSRCHAVVPPEPF 1367
W PCS E +A Y A C +LK +PF RCH+ V P +
Sbjct: 561 SSCHDKLDWLDDPCSLNIE-----SANY-----AEHWCSLLKKTETPFGRCHSAVDPAEY 610
Query: 1368 FAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLC---VVGCPLERGF 1424
+ C YD C C + + CLC AL +YA C GV +C V CP + F
Sbjct: 611 YKRCKYDTCNC---QNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVF 667
Query: 1425 VFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP--GCQCP-AGLVEHEAHCIPPEAC 1478
+++ C +TC + L E +HC+ P GC CP ++ + C+P C
Sbjct: 668 LYNL--TTCQQTCRS----LSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKC 718
Score = 150 bits (378), Expect = 1e-35
Identities = 101/336 (30%), Positives = 160/336 (47%), Gaps = 28/336 (8%)
Query: 1150 CMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG--DFSVHVTNDDRGRSGVAWTQEVAV 1207
C +G+ HY+TFDG + F G C Y A DC +F+VH+ A + + +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
Query: 1208 LLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVE 1267
+ D + L + AV ++G V+ P LL + +T + +++ GL ++W+ + +
Sbjct: 97 TIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKV-YSRAGLTLMWNREDALM 154
Query: 1268 VSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPC-SAG 1326
+ + ++ TCGLCG++NG +G+L S FGN ++++ P C
Sbjct: 155 LELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLF-SPLEFGNMQKINQ---PDVVCEDPE 210
Query: 1327 REVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADA 1386
EV P + +RA E +L + F+ C +VP EP+ AC D C C PG D
Sbjct: 211 EEVAPASCSEHRAECER-----LLTAEAFADCQDLVPLEPYLRACQQDRCRC-PG--GDT 262
Query: 1387 CLCDALEAYASHCRQAGVTP-TWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG 1445
C+C + ++ C AG P WR TLC CP V+ E G PC TC H+
Sbjct: 263 CVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCP--GNLVYLESGSPCMDTC--SHL--- 315
Query: 1446 ELAAHCVRPCVPGCQCPAGLVEH---EAHCIPPEAC 1478
E+++ C + GC CP G V ++ C+P C
Sbjct: 316 EVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQC 351
Score = 130 bits (328), Expect = 7e-30
Identities = 130/492 (26%), Positives = 191/492 (38%), Gaps = 72/492 (14%)
Query: 1039 DPCY------TCQCQDLTWLCIHQACPELSCPLSERHTP--------PGSCCPVCRAPTQ 1084
D CY +C + W C P P + TP P P + P
Sbjct: 4356 DTCYFVNCSLSCTLEFYNWSCPSTPSPT---PTPSKSTPTPSKPSSTPSKPTPGTKPP-- 4410
Query: 1085 SCVHQGREVASGERWTVDTCTSCSCMAG-TVRCQSQRCSP-----LSCGPDKAPALSPGS 1138
C E W + C +C TV C P S G P
Sbjct: 4411 ECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDG 4470
Query: 1139 CCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG--DFSVHVTN---DD 1193
CC C +GDPHY TFDG +QG+C+YVL ++ +F V++ N D
Sbjct: 4471 CCWHW-ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDP 4529
Query: 1194 RGRSGVA-------WTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGH 1246
+ TQEV + M +Q V V+ VALP+ + L + +
Sbjct: 4530 NDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQ---VQVNRQAVALPYKKYGLEVYQSGIN 4586
Query: 1247 TVILHAQPGLQVLWDGQSQVEVSVP-GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEA 1305
V+ + G+ V ++G S V +P + T G CG DD P G ++ +
Sbjct: 4587 YVVDIPELGVLVSYNGLS-FSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCE 4645
Query: 1306 AFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR------EANARCGVLKSSPFSRCH 1359
A + W V++ P P S+ P + + C ++K S F++CH
Sbjct: 4646 AAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCH 4705
Query: 1360 AVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPT--LCVVG 1417
A+VPP+ ++ ACV+D C PGSS + C +L+AYA+ C Q + WR T C+V
Sbjct: 4706 ALVPPQHYYDACVFDSCFM-PGSSLE---CASLQAYAALCAQQNICLDWRNHTHGACLVE 4761
Query: 1418 CPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEH--------- 1468
CP R + CGP TC + V GC CP G + +
Sbjct: 4762 CPSHR--EYQACGPAEEPTCKSSSSQQNNTV------LVEGCFCPEGTMNYAPGFDVCVK 4813
Query: 1469 EAHCIPPEACPQ 1480
C+ P+ P+
Sbjct: 4814 TCGCVGPDNVPR 4825
Score = 58.9 bits (141), Expect = 4e-08
Identities = 94/412 (22%), Positives = 135/412 (32%), Gaps = 87/412 (21%)
Query: 117 CVCQDGAAHCGP--QAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGA--VQCQGPS 172
C C +G + P + C + GE F D C C CL G + CQ
Sbjct: 4795 CFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKR 4853
Query: 173 CSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPC---RICRCLEGHIQCRQRE 229
CS+ C E G++ P D C +C+C C+++
Sbjct: 4854 CSQKPVTH------------CVEDGTYLATE---VNPADTCCNITVCKCNTS--LCKEKP 4896
Query: 230 CASLCPY----PARPLPGTCCPV--CDG---CFLNGREHRSGEPVGSGDPCSHCRCAN-- 278
S+CP ++ +PG CCP C+ C E++ G PV S C C C +
Sbjct: 4897 --SVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSK-CQDCVCTDKV 4953
Query: 279 -GSVQCEPLPCPPVPCR---HPG----KIPGQCCPVCDGCEY------QGHQYQSQETFR 324
+ + C VPC PG + PG+CC C+ H F+
Sbjct: 4954 DNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFK 5013
Query: 325 LQERGLCVRCSC---------QAGEVSCEEQECPV-TPCALPASGRQLCPACELDGEE-- 372
+ C SC ++C + + P ++ C C E
Sbjct: 5014 SDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRV 5073
Query: 373 --FAEGVQWEPDGRPCTACVCQDGVP-KCGAVLCPPAPCQHPTQPPGACCPSCDSC---- 425
V E CT V + CG + A Q A SC C
Sbjct: 5074 PCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQ-------ALDHSCSCCKEEK 5126
Query: 426 TYHSQVY---ANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGP 474
T +V NG + T + +C CQD C L P T R + P
Sbjct: 5127 TSQREVVLSCPNGGSLTHTYTHIESCQCQD--TVCGL---PTGTSRRARRSP 5173
Score = 51.6 bits (122), Expect = 6e-06
Identities = 49/169 (28%), Positives = 64/169 (37%), Gaps = 29/169 (17%)
Query: 106 GARWEPDACTACVCQDGAAH--CGP----QAHLPHCRGCSQNGQTYGNGETFSPDAC--- 156
G +E D C CVC +G + C P Q + HC ++G TY E D C
Sbjct: 4828 GEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHC---VEDG-TYLATEVNPADTCCNI 4882
Query: 157 TTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDP---- 212
T C+C T + + C ++S PG CCP E HG PG P
Sbjct: 4883 TVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSS 4942
Query: 213 -CRICRC--------LEGHIQCRQRECASLCP--YPARPLPGTCCPVCD 250
C+ C C L I C C + C + PG CC C+
Sbjct: 4943 KCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCE 4991
Score = 49.3 bits (116), Expect = 3e-05
Identities = 65/275 (23%), Positives = 90/275 (32%), Gaps = 85/275 (30%)
Query: 916 CSSCVCHEGV--VTCARIQC----ISSCAQP------RQGPHDCCPQCSDCEHEGRKYEP 963
C +CVC EG + C +C ++ C + P D C + C+
Sbjct: 4835 CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCK-------- 4886
Query: 964 GESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTC-AEA 1022
C +C+ +P CP +G + PG CCP E+
Sbjct: 4887 ----------CNTSLCKEKPS----------VCP--LGFEVKSKMVPG--RCCPFYWCES 4922
Query: 1023 LSNCSEGLLGSELAPPDPCYTCQCQDLTWL-------------CIHQACPELSCPLSERH 1069
C G +E P P Y+ +CQD C H C P E
Sbjct: 4923 KGVCVHG--NAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELM 4980
Query: 1070 TPPGSCCPVC--------RAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRC 1121
PG CC C R Q + + + S + + CT SC V+ +Q
Sbjct: 4981 EAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKSDPK---NNCTFFSC----VKIHNQLI 5033
Query: 1122 SPLS---CGPDKAPALSPGS-------CCPRCLPR 1146
S +S C A PGS CC C PR
Sbjct: 5034 SSVSNITCPNFDASICIPGSITFMPNGCCKTCTPR 5068
Score = 46.6 bits (109), Expect = 2e-04
Identities = 52/207 (25%), Positives = 70/207 (33%), Gaps = 40/207 (19%)
Query: 460 VDCPPTTCARPQS--GPGQCCPRCPDC--ILEEEVFVDGESFSHPRDP----CQE--CRC 509
++ P C P+ P C +C +L E F D + P +P CQ+ CRC
Sbjct: 199 INQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLV-PLEPYLRACQQDRCRC 257
Query: 510 QEGHAH-CQPRPCPRAPCAHP--LPG-----TCCPNDCSGCAFGGKEYPSGADFPHPSDP 561
G C C+H PG T CP C P + P
Sbjct: 258 PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTC----------PGNLVYLESGSP 307
Query: 562 CR-LCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSP 620
C C L + C R CPE + +GC H R +
Sbjct: 308 CMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDI------GDSGCVPVSQCHCRLHGHLYT 361
Query: 621 PG----DPCRRCLCLDGSVSCQRLPCP 643
PG + C +C+C G C+ LPCP
Sbjct: 362 PGQEITNDCEQCVCNAGRWVCKDLPCP 388
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/295 (24%), Positives = 102/295 (34%), Gaps = 85/295 (28%)
Query: 660 DGCLYQGK--EFASGERFPSPTAACHLCLCWEGS------VSC----EPKACAPA----- 702
D C G E AS + + + A ++CL W V C E +AC PA
Sbjct: 4720 DSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTC 4779
Query: 703 ----------------LCP-----FPARGDCCPDCDGCEYLGESYLSNQEFPDPRE-PCN 740
CP + D C GC +G + +EF + E C
Sbjct: 4780 KSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC--VGPDNVP-REFGEHFEFDCK 4836
Query: 741 LCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCS 800
C CL G C+P CS P HC G A T +P D C+
Sbjct: 4837 NCVCLEGGSGI---ICQPKRCSQK--PVTHCVED-------GTYLA---TEVNPADTCCN 4881
Query: 801 LCTCQEGSMRCQKKPCPPALCP-------HPSPGPCFCPV--CHS---CLSQGREHQDGE 848
+ C+ + C++K P++CP PG C CP C S C+ E+Q G
Sbjct: 4882 ITVCKCNTSLCKEK---PSVCPLGFEVKSKMVPGRC-CPFYWCESKGVCVHGNAEYQPGS 4937
Query: 849 EFEGPAGSCEWCRCQAGQVSCVRLQ---CPPLPCKLQ-------VTERGSCCPRC 893
+ C+ C C + L C +PC + G CC +C
Sbjct: 4938 PVY--SSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKC 4990
Score = 42.4 bits (98), Expect = 0.003
Identities = 60/226 (26%), Positives = 79/226 (34%), Gaps = 31/226 (13%)
Query: 660 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP--ALCPFPARGDCCPDCD 717
DG L+ EF + ++ P C + P +C+ A C + DC
Sbjct: 184 DGVLFSPLEFGNMQKINQPDVVCE-----DPEEEVAPASCSEHRAECERLLTAEAFADCQ 238
Query: 718 GCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCP-TCQ 776
L E YL + R P TC+ V R C G + CP TC
Sbjct: 239 DLVPL-EPYLRACQQDRCRCPGG-DTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCP 296
Query: 777 GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCP----HPSPGPCFC- 831
G + V SG P C+ E S C++ CP + G C
Sbjct: 297 G---NLVYLESGS-------PCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCV 346
Query: 832 PV--CHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCP 875
PV CH C G + G+E CE C C AG+ C L CP
Sbjct: 347 PVSQCH-CRLHGHLYTPGQEI---TNDCEQCVCNAGRWVCKDLPCP 388
Score = 42.4 bits (98), Expect = 0.003
Identities = 121/584 (20%), Positives = 177/584 (30%), Gaps = 132/584 (22%)
Query: 353 CALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPT 412
C S + P+ E+ A QW + C K AV P T
Sbjct: 4625 CTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGG---KT 4681
Query: 413 QPPGACCPS--C----DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTT 466
P C PS C DS Q++ DA +C ++ C+ +
Sbjct: 4682 TPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDA-CVFDSCFMPGSSLECASLQAYAAL 4740
Query: 467 CARPQ-------SGPGQCCPRCPD------CILEEEVFVDGESFSHPRDPCQE-CRCQEG 512
CA+ G C CP C EE S E C C EG
Sbjct: 4741 CAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEG 4800
Query: 513 HAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGN- 571
+ AP TC C G +E+ +F C+ C CL G
Sbjct: 4801 TMNY-------APGFDVCVKTC---GCVGPDNVPREFGEHFEFD-----CKNCVCLEGGS 4845
Query: 572 -VQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLC 630
+ C +RC P C G A +P C +C
Sbjct: 4846 GIICQPKRCSQKPVTH-----------------CVEDGTYLATE---VNPADTCCNITVC 4885
Query: 631 LDGSVSCQRLP--CPPAPCAHPRQGP--CCPS--CDG---CLYQGKEFASGERFPSPTAA 681
+ C+ P CP + P CCP C+ C++ E+ G P ++
Sbjct: 4886 KCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGS--PVYSSK 4943
Query: 682 CHLCLCWE--------GSVSCEP----KACAPALCPFPARGDCCPDCDGCEYL------G 723
C C+C + ++C +C+P A G+CC C+ +
Sbjct: 4944 CQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQ 5003
Query: 724 ESYLSNQEF-PDPREPCNLCTCLG---------GFVTCGRRPCE--PPGCSHPLIPSGHC 771
L +F DP+ C +C+ +TC PG S +P+G C
Sbjct: 5004 HVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPG-SITFMPNG-C 5061
Query: 772 CPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFC 831
C TC P + T C+ + C + + G C
Sbjct: 5062 CKTC-----------------TPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGT 5104
Query: 832 PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCP 875
V +S +Q +H SC C+ + V L CP
Sbjct: 5105 FVMYSAKAQALDH-----------SCSCCKEEKTSQREVVLSCP 5137
Score = 41.2 bits (95), Expect = 0.008
Identities = 61/248 (24%), Positives = 84/248 (33%), Gaps = 60/248 (24%)
Query: 74 NKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLP 133
N D TR + S E G +W E A C D + + P + P
Sbjct: 1000 NNDFTTRDHMVVSSELD--------FGNSWKE----------APTCPDVSTNPEPCSLNP 1041
Query: 134 HCRGCSQNGQTYGNGETFSP-----------DACT--TCRCLTGAVQCQGPSCSELNCLE 180
H R ++ + FS +AC +C C TG C+ + + +
Sbjct: 1042 HRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGG-DCECFCSAVASYAQ 1100
Query: 181 SCTPPGEC--------CPICCTEGGSHWEHGQEWTTPGDPC-----RICRCLEG---HIQ 224
CT G C CPI C H EW +PC CR + G +I
Sbjct: 1101 ECTKEGACVFWRTPDLCPIFCDYYNP--PHECEWHY--EPCGNRSFETCRTINGIHSNIS 1156
Query: 225 CRQRE-CASLCPYPARPLPGTCCPVCD-----GCFLNGREHRSGEPVGSGDPCSHCRCAN 278
E C CP RP+ C GC++ + G V + + C C C N
Sbjct: 1157 VSYLEGCYPRCPKD-RPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTN 1215
Query: 279 GS-VQCEP 285
S V C P
Sbjct: 1216 SSQVVCRP 1223
Score = 38.5 bits (88), Expect = 0.049
Identities = 71/316 (22%), Positives = 98/316 (31%), Gaps = 113/316 (35%)
Query: 126 CGPQAHLPHCRGCS--QNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCT 183
CGP A P C+ S QN G C C G + P C+++C
Sbjct: 4771 CGP-AEEPTCKSSSSQQNNTVLVEG----------CFCPEGTMN-YAPGFDV--CVKTCG 4816
Query: 184 PPG-ECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGH--IQCRQRECASLCPYPARP 240
G + P E G H+E C+ C CLEG I C+ + C+
Sbjct: 4817 CVGPDNVP---REFGEHFEFD---------CKNCVCLEGGSGIICQPKRCSQK------- 4857
Query: 241 LPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH---CRCANGSVQCEPLPCPPVPCRHPG 297
P T C V DG +L V D C + C+C + +P CP
Sbjct: 4858 -PVTHC-VEDGTYL-------ATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSK 4908
Query: 298 KIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPA 357
+PG+CCP + + +G+CV + + + PV
Sbjct: 4909 MVPGRCCPF----------------YWCESKGVCVHGNAE------YQPGSPVY------ 4940
Query: 358 SGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPK---CGAVLCPPAPCQHPTQP 414
C CVC D V + C PC P
Sbjct: 4941 -------------------------SSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSP 4975
Query: 415 -------PGACCPSCD 423
PG CC C+
Sbjct: 4976 GFELMEAPGECCKKCE 4991
Score = 37.4 bits (85), Expect = 0.11
Identities = 62/267 (23%), Positives = 96/267 (35%), Gaps = 52/267 (19%)
Query: 113 ACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT---TCR--------C 161
ACTA G G + H+ C+++ + N + F + T TCR C
Sbjct: 638 ACTA----KGVMLWGWREHV-----CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHC 688
Query: 162 LTGAVQCQGPSCSELNCLESCTPPGECCPIC---CTEGGSHWEHGQEWTTPGDPCRICRC 218
L G G C + L+ G C P+ C G + E G + C +CR
Sbjct: 689 LEGFAPVDGCGCPDHTFLDE---KGRCVPLAKCSCYHRGLYLEAGDVVVRQEERC-VCR- 743
Query: 219 LEGHIQCRQ-RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCA 277
+G + CRQ R C P + C + S + + +G H C
Sbjct: 744 -DGRLHCRQIRLIGQSCTAPKIHMD---CSNLTALATSKPRALSCQTLAAG--YYHTECV 797
Query: 278 NGSVQCEPLPCPP--VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCS 335
+G V CP + G + + CP C + Y S ++ C C+
Sbjct: 798 SGCV------CPDGLMDDGRGGCVVEKECP----CVHNNDLYSSGAKIKVD----CNTCT 843
Query: 336 CQAGEVSCEEQECPVTPCALPASGRQL 362
C+ G C + C T C++ SG +
Sbjct: 844 CKRGRWVCTQAVCHGT-CSIYGSGHYI 869
Score = 34.3 bits (77), Expect = 0.93
Identities = 44/163 (26%), Positives = 53/163 (32%), Gaps = 47/163 (28%)
Query: 216 CRCLEGH------IQCRQRECASLCPYPARPLPGTCCP-VCDGCFLNGREHRSGEPVGSG 268
CRC G + R+C+ P T CP C G N SG P
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPG---NLVYLESGSPCM-- 309
Query: 269 DPCSH--------------CRCANGSVQCE--PLPCPPVPCRHPGKIPGQCCPVCDGCEY 312
D CSH C C G+V + C PV H C
Sbjct: 310 DTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCH--------------CRL 355
Query: 313 QGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCAL 355
GH Y + C +C C AG C++ CP T CAL
Sbjct: 356 HGHLYTPGQEITND----CEQCVCNAGRWVCKDLPCPGT-CAL 393
Score = 33.9 bits (76), Expect = 1.2
Identities = 57/254 (22%), Positives = 82/254 (32%), Gaps = 58/254 (22%)
Query: 535 CPNDCSGCAFGGKEYPSGADFPHPSDPCR-LCRCLSGNVQCLARRCVPLP---CPEPVLL 590
C D C P+ F + C+ CR LS P+ CP+ L
Sbjct: 654 CNKDVGSC-------PNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFL 706
Query: 591 P--GECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPC----RRCLCLDGSVSCQRLPCPP 644
G C P A C H+ + GD RC+C DG + C+++
Sbjct: 707 DEKGRCVPL--AKCSC--------YHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIG 756
Query: 645 APCAHPRQGPCCPSCDGCLYQGKEFASGERFPS---PTAACHLCLCWEGSVSCEPKACAP 701
C P+ C + S + + T C+C +G +
Sbjct: 757 QSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMD-------- 808
Query: 702 ALCPFPARGDC-----CPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPC 756
RG C CP C + + Y S + + CN CTC G C + C
Sbjct: 809 -----DGRGGCVVEKECP----CVHNNDLYSSGAKI---KVDCNTCTCKRGRWVCTQAVC 856
Query: 757 EPPGCSHPLIPSGH 770
CS + SGH
Sbjct: 857 HGT-CS--IYGSGH 867
Score = 33.5 bits (75), Expect = 1.6
Identities = 45/204 (22%), Positives = 74/204 (36%), Gaps = 39/204 (19%)
Query: 744 CLGGFVTCGRRPCEPPGC-SHPLIPS-GHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS 800
CL GF P + GC H + G C P + C + G+ +G+ + +
Sbjct: 688 CLEGFA-----PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEER--- 739
Query: 801 LCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWC 860
C C++G + C++ C P + S+ R A SC+
Sbjct: 740 -CVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPR-----------ALSCQTL 787
Query: 861 RCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEGSRWVPPDS 914
CV CP L RG C CP C+ + + + G++ + D
Sbjct: 788 AAGYYHTECVSGCVCPD---GLMDDGRGGCVVEKECP----CVHNNDLYSSGAK-IKVD- 838
Query: 915 ACSSCVCHEGVVTCARIQCISSCA 938
C++C C G C + C +C+
Sbjct: 839 -CNTCTCKRGRWVCTQAVCHGTCS 861
Score = 33.1 bits (74), Expect = 2.1
Identities = 35/151 (23%), Positives = 46/151 (30%), Gaps = 27/151 (17%)
Query: 333 RCSCQAGEVSCEEQECPVTPCALPASGRQ-------LCPACELDGEEFAEGVQWEPDGRP 385
RC C G+ + A GR LCP + E G P
Sbjct: 254 RCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLES------GSP 307
Query: 386 C--------TACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQN 437
C + +C++ + CP G S C H +Y GQ
Sbjct: 308 CMDTCSHLEVSSLCEEH--RMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQE 365
Query: 438 FTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
T+ C C C G C + C P TCA
Sbjct: 366 ITN---DCEQCVCNAGRWVCKDLPC-PGTCA 392
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 189 bits (479), Expect = 2e-47
Identities = 131/461 (28%), Positives = 197/461 (42%), Gaps = 59/461 (12%)
Query: 1046 CQDLTWLCIHQACPE-LSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTC 1104
CQ L H C CP G C P CVH +SG + VD C
Sbjct: 685 CQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP---CVHNNDLYSSGAKIKVD-C 740
Query: 1105 TSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGR 1164
+C+C G C C +C +G HY TFDG+
Sbjct: 741 NTCTCKRGRWVCTQAVCH-------------------------GTCSIYGSGHYITFDGK 775
Query: 1165 LLHFQGSCSYVLAKD-----CHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD 1219
F G CSYV +D G FS+ N G +GV ++ + + +G ++L
Sbjct: 776 YYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDK 835
Query: 1220 GAVTV---DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQG 1276
V + +GH VA + G +++ + G+ V+WD ++ V + + SY+G
Sbjct: 836 HRVVIQRDEGHHVAYTTREV--------GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKG 887
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAG 1336
CGLCGNF+ + +D + +++ SE FGNSW+ + P P +PC
Sbjct: 888 TVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA----PTCP-DVSTNPEPCSLNP 942
Query: 1337 YRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYA 1396
+R R A +C +LKSS FS CH+ V P+PF+ ACV+D C+C G + C C A+ +YA
Sbjct: 943 HR-RSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCE-CFCSAVASYA 1000
Query: 1397 SHCRQAGVTPTWRGPTLCVVGC-----PLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
C + G WR P LC + C P E + ++ CG TC + ++
Sbjct: 1001 QECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSY 1060
Query: 1452 VRPCVPGCQCPAGLVEHE-AHCIPPEACPQVLLTGDQPLGA 1491
+ C P C + E + C+ + C + P GA
Sbjct: 1061 LEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1101
Score = 135 bits (341), Expect = 2e-31
Identities = 96/324 (29%), Positives = 152/324 (46%), Gaps = 30/324 (9%)
Query: 1150 CMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG--DFSVHVTNDDRGRSGVAWTQEVAV 1207
C +G+ HY+TFDG + F G C Y A DC +F+VH+ A + + +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
Query: 1208 LLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVE 1267
+ D + L + AV ++G V+ P LL + +T + +++ GL ++W+ + +
Sbjct: 97 TIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKV-YSRAGLTLMWNREDALM 154
Query: 1268 VSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPC-SAG 1326
+ + ++ TCGLCG++NG +G+L S FGN ++++ P C
Sbjct: 155 LELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLF-SPLEFGNMQKINQ---PDVVCEDPE 210
Query: 1327 REVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADA 1386
EV P + +RA E +L + F+ C +VP EP+ AC D C C PG D
Sbjct: 211 EEVAPASCSEHRAECER-----LLTAEAFADCQDLVPLEPYLRACQQDRCRC-PG--GDT 262
Query: 1387 CLCDALEAYASHCRQAGVTP-TWRGPTLCV-----VGCPLERGFVFDECGPPCPRTCFNQ 1440
C+C + ++ C AG P WR T V CP V+ E G PC TC
Sbjct: 263 CVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCP--GNLVYLESGSPCMDTC--S 318
Query: 1441 HIPLGELAAHCVRPCVPGCQCPAG 1464
H+ E+++ C + GC CP G
Sbjct: 319 HL---EVSSLCEEHRMDGCFCPEG 339
Score = 130 bits (328), Expect = 7e-30
Identities = 130/492 (26%), Positives = 191/492 (38%), Gaps = 72/492 (14%)
Query: 1039 DPCY------TCQCQDLTWLCIHQACPELSCPLSERHTP--------PGSCCPVCRAPTQ 1084
D CY +C + W C P P + TP P P + P
Sbjct: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPT---PTPSKSTPTPSKPSSTPSKPTPGTKPP-- 1870
Query: 1085 SCVHQGREVASGERWTVDTCTSCSCMAG-TVRCQSQRCSP-----LSCGPDKAPALSPGS 1138
C E W + C +C TV C P S G P
Sbjct: 1871 ECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDG 1930
Query: 1139 CCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG--DFSVHVTN---DD 1193
CC C +GDPHY TFDG +QG+C+YVL ++ +F V++ N D
Sbjct: 1931 CCWHW-ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDP 1989
Query: 1194 RGRSGVA-------WTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGH 1246
+ TQEV + M +Q V V+ VALP+ + L + +
Sbjct: 1990 NDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQ---VQVNRQAVALPYKKYGLEVYQSGIN 2046
Query: 1247 TVILHAQPGLQVLWDGQSQVEVSVP-GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEA 1305
V+ + G+ V ++G S V +P + T G CG DD P G ++ +
Sbjct: 2047 YVVDIPELGVLVSYNGLS-FSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCE 2105
Query: 1306 AFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR------EANARCGVLKSSPFSRCH 1359
A + W V++ P P S+ P + + C ++K S F++CH
Sbjct: 2106 AAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCH 2165
Query: 1360 AVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPT--LCVVG 1417
A+VPP+ ++ ACV+D C PGSS + C +L+AYA+ C Q + WR T C+V
Sbjct: 2166 ALVPPQHYYDACVFDSCFM-PGSSLE---CASLQAYAALCAQQNICLDWRNHTHGACLVE 2221
Query: 1418 CPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEH--------- 1468
CP R + CGP TC + V GC CP G + +
Sbjct: 2222 CPSHR--EYQACGPAEEPTCKSSSSQQNNTV------LVEGCFCPEGTMNYAPGFDVCVK 2273
Query: 1469 EAHCIPPEACPQ 1480
C+ P+ P+
Sbjct: 2274 TCGCVGPDNVPR 2285
Score = 111 bits (278), Expect = 5e-24
Identities = 87/293 (29%), Positives = 130/293 (44%), Gaps = 37/293 (12%)
Query: 1204 EVAVLLGDMAVRLL---QDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPG--LQV 1258
+ VLL D ++ DG+V ++ V LP + + +++ G LQV
Sbjct: 346 KTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQV 405
Query: 1259 LWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGL- 1317
Q+ V++ + QG+ GLCGNFNG DD + GL+ + A F N+W+
Sbjct: 406 QLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCH 465
Query: 1318 ----WPGRPCSAGREVDPCRAAGYRARREANARCGVLK--SSPFSRCHAVVPPEPFFAAC 1371
W PCS E +A Y A C +LK +PF RCH+ V P ++ C
Sbjct: 466 DKLDWLDDPCSLNIE-----SANY-----AEHWCSLLKKTETPFGRCHSAVDPAEYYKRC 515
Query: 1372 VYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLC---VVGCPLERGFVFDE 1428
YD C C + + CLC AL +YA C GV +C V CP + F+++
Sbjct: 516 KYDTCNC---QNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNL 572
Query: 1429 CGPPCPRTCFNQHIPLGELAAHCVRPCVP--GCQCP-AGLVEHEAHCIPPEAC 1478
C +TC + L E +HC+ P GC CP ++ + C+P C
Sbjct: 573 --TTCQQTCRS----LSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKC 619
Score = 58.9 bits (141), Expect = 4e-08
Identities = 94/412 (22%), Positives = 135/412 (32%), Gaps = 87/412 (21%)
Query: 117 CVCQDGAAHCGP--QAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGA--VQCQGPS 172
C C +G + P + C + GE F D C C CL G + CQ
Sbjct: 2255 CFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKR 2313
Query: 173 CSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPC---RICRCLEGHIQCRQRE 229
CS+ C E G++ P D C +C+C C+++
Sbjct: 2314 CSQKPVTH------------CVEDGTYLATE---VNPADTCCNITVCKCNTS--LCKEKP 2356
Query: 230 CASLCPY----PARPLPGTCCPV--CDG---CFLNGREHRSGEPVGSGDPCSHCRCAN-- 278
S+CP ++ +PG CCP C+ C E++ G PV S C C C +
Sbjct: 2357 --SVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSK-CQDCVCTDKV 2413
Query: 279 -GSVQCEPLPCPPVPCR---HPG----KIPGQCCPVCDGCEY------QGHQYQSQETFR 324
+ + C VPC PG + PG+CC C+ H F+
Sbjct: 2414 DNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFK 2473
Query: 325 LQERGLCVRCSC---------QAGEVSCEEQECPV-TPCALPASGRQLCPACELDGEE-- 372
+ C SC ++C + + P ++ C C E
Sbjct: 2474 SDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRV 2533
Query: 373 --FAEGVQWEPDGRPCTACVCQDGVP-KCGAVLCPPAPCQHPTQPPGACCPSCDSC---- 425
V E CT V + CG + A Q A SC C
Sbjct: 2534 PCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQ-------ALDHSCSCCKEEK 2586
Query: 426 TYHSQVY---ANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGP 474
T +V NG + T + +C CQD C L P T R + P
Sbjct: 2587 TSQREVVLSCPNGGSLTHTYTHIESCQCQD--TVCGL---PTGTSRRARRSP 2633
Score = 51.6 bits (122), Expect = 6e-06
Identities = 49/169 (28%), Positives = 64/169 (37%), Gaps = 29/169 (17%)
Query: 106 GARWEPDACTACVCQDGAAH--CGP----QAHLPHCRGCSQNGQTYGNGETFSPDAC--- 156
G +E D C CVC +G + C P Q + HC ++G TY E D C
Sbjct: 2288 GEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHC---VEDG-TYLATEVNPADTCCNI 2342
Query: 157 TTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDP---- 212
T C+C T + + C ++S PG CCP E HG PG P
Sbjct: 2343 TVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSS 2402
Query: 213 -CRICRC--------LEGHIQCRQRECASLCP--YPARPLPGTCCPVCD 250
C+ C C L I C C + C + PG CC C+
Sbjct: 2403 KCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCE 2451
Score = 49.3 bits (116), Expect = 3e-05
Identities = 65/275 (23%), Positives = 90/275 (32%), Gaps = 85/275 (30%)
Query: 916 CSSCVCHEGV--VTCARIQC----ISSCAQP------RQGPHDCCPQCSDCEHEGRKYEP 963
C +CVC EG + C +C ++ C + P D C + C+
Sbjct: 2295 CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCK-------- 2346
Query: 964 GESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTC-AEA 1022
C +C+ +P CP +G + PG CCP E+
Sbjct: 2347 ----------CNTSLCKEKPS----------VCP--LGFEVKSKMVPG--RCCPFYWCES 2382
Query: 1023 LSNCSEGLLGSELAPPDPCYTCQCQDLTWL-------------CIHQACPELSCPLSERH 1069
C G +E P P Y+ +CQD C H C P E
Sbjct: 2383 KGVCVHG--NAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELM 2440
Query: 1070 TPPGSCCPVC--------RAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRC 1121
PG CC C R Q + + + S + + CT SC V+ +Q
Sbjct: 2441 EAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKSDPK---NNCTFFSC----VKIHNQLI 2493
Query: 1122 SPLS---CGPDKAPALSPGS-------CCPRCLPR 1146
S +S C A PGS CC C PR
Sbjct: 2494 SSVSNITCPNFDASICIPGSITFMPNGCCKTCTPR 2528
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/295 (24%), Positives = 102/295 (34%), Gaps = 85/295 (28%)
Query: 660 DGCLYQGK--EFASGERFPSPTAACHLCLCWEGS------VSC----EPKACAPA----- 702
D C G E AS + + + A ++CL W V C E +AC PA
Sbjct: 2180 DSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTC 2239
Query: 703 ----------------LCP-----FPARGDCCPDCDGCEYLGESYLSNQEFPDPRE-PCN 740
CP + D C GC +G + +EF + E C
Sbjct: 2240 KSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC--VGPDNVP-REFGEHFEFDCK 2296
Query: 741 LCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCS 800
C CL G C+P CS P HC G A T +P D C+
Sbjct: 2297 NCVCLEGGSGI---ICQPKRCSQK--PVTHCVED-------GTYLA---TEVNPADTCCN 2341
Query: 801 LCTCQEGSMRCQKKPCPPALCP-------HPSPGPCFCPV--CHS---CLSQGREHQDGE 848
+ C+ + C++K P++CP PG C CP C S C+ E+Q G
Sbjct: 2342 ITVCKCNTSLCKEK---PSVCPLGFEVKSKMVPGRC-CPFYWCESKGVCVHGNAEYQPGS 2397
Query: 849 EFEGPAGSCEWCRCQAGQVSCVRLQ---CPPLPCKLQ-------VTERGSCCPRC 893
+ C+ C C + L C +PC + G CC +C
Sbjct: 2398 PVY--SSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKC 2450
Score = 42.4 bits (98), Expect = 0.003
Identities = 121/584 (20%), Positives = 177/584 (30%), Gaps = 132/584 (22%)
Query: 353 CALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPT 412
C S + P+ E+ A QW + C K AV P T
Sbjct: 2085 CTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGG---KT 2141
Query: 413 QPPGACCPS--C----DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTT 466
P C PS C DS Q++ DA +C ++ C+ +
Sbjct: 2142 TPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDA-CVFDSCFMPGSSLECASLQAYAAL 2200
Query: 467 CARPQ-------SGPGQCCPRCPD------CILEEEVFVDGESFSHPRDPCQE-CRCQEG 512
CA+ G C CP C EE S E C C EG
Sbjct: 2201 CAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEG 2260
Query: 513 HAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGN- 571
+ AP TC C G +E+ +F C+ C CL G
Sbjct: 2261 TMNY-------APGFDVCVKTC---GCVGPDNVPREFGEHFEFD-----CKNCVCLEGGS 2305
Query: 572 -VQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLC 630
+ C +RC P C G A +P C +C
Sbjct: 2306 GIICQPKRCSQKPVTH-----------------CVEDGTYLATE---VNPADTCCNITVC 2345
Query: 631 LDGSVSCQRLP--CPPAPCAHPRQGP--CCPS--CDG---CLYQGKEFASGERFPSPTAA 681
+ C+ P CP + P CCP C+ C++ E+ G P ++
Sbjct: 2346 KCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGS--PVYSSK 2403
Query: 682 CHLCLCWE--------GSVSCEP----KACAPALCPFPARGDCCPDCDGCEYL------G 723
C C+C + ++C +C+P A G+CC C+ +
Sbjct: 2404 CQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQ 2463
Query: 724 ESYLSNQEF-PDPREPCNLCTCLG---------GFVTCGRRPCE--PPGCSHPLIPSGHC 771
L +F DP+ C +C+ +TC PG S +P+G C
Sbjct: 2464 HVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPG-SITFMPNG-C 2521
Query: 772 CPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFC 831
C TC P + T C+ + C + + G C
Sbjct: 2522 CKTC-----------------TPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGT 2564
Query: 832 PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCP 875
V +S +Q +H SC C+ + V L CP
Sbjct: 2565 FVMYSAKAQALDH-----------SCSCCKEEKTSQREVVLSCP 2597
Score = 41.2 bits (95), Expect = 0.008
Identities = 61/248 (24%), Positives = 84/248 (33%), Gaps = 60/248 (24%)
Query: 74 NKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLP 133
N D TR + S E G +W E A C D + + P + P
Sbjct: 901 NNDFTTRDHMVVSSELD--------FGNSWKE----------APTCPDVSTNPEPCSLNP 942
Query: 134 HCRGCSQNGQTYGNGETFSP-----------DACT--TCRCLTGAVQCQGPSCSELNCLE 180
H R ++ + FS +AC +C C TG C+ + + +
Sbjct: 943 HRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGG-DCECFCSAVASYAQ 1001
Query: 181 SCTPPGEC--------CPICCTEGGSHWEHGQEWTTPGDPC-----RICRCLEG---HIQ 224
CT G C CPI C H EW +PC CR + G +I
Sbjct: 1002 ECTKEGACVFWRTPDLCPIFCDYYNP--PHECEWHY--EPCGNRSFETCRTINGIHSNIS 1057
Query: 225 CRQRE-CASLCPYPARPLPGTCCPVCD-----GCFLNGREHRSGEPVGSGDPCSHCRCAN 278
E C CP RP+ C GC++ + G V + + C C C N
Sbjct: 1058 VSYLEGCYPRCPKD-RPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTN 1116
Query: 279 GS-VQCEP 285
S V C P
Sbjct: 1117 SSQVVCRP 1124
Score = 38.5 bits (88), Expect = 0.049
Identities = 71/316 (22%), Positives = 98/316 (31%), Gaps = 113/316 (35%)
Query: 126 CGPQAHLPHCRGCS--QNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCT 183
CGP A P C+ S QN G C C G + P C+++C
Sbjct: 2231 CGP-AEEPTCKSSSSQQNNTVLVEG----------CFCPEGTMN-YAPGFDV--CVKTCG 2276
Query: 184 PPG-ECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGH--IQCRQRECASLCPYPARP 240
G + P E G H+E C+ C CLEG I C+ + C+
Sbjct: 2277 CVGPDNVP---REFGEHFEFD---------CKNCVCLEGGSGIICQPKRCSQK------- 2317
Query: 241 LPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH---CRCANGSVQCEPLPCPPVPCRHPG 297
P T C V DG +L V D C + C+C + +P CP
Sbjct: 2318 -PVTHC-VEDGTYL-------ATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSK 2368
Query: 298 KIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPA 357
+PG+CCP + + +G+CV + + + PV
Sbjct: 2369 MVPGRCCPF----------------YWCESKGVCVHGNAE------YQPGSPVY------ 2400
Query: 358 SGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPK---CGAVLCPPAPCQHPTQP 414
C CVC D V + C PC P
Sbjct: 2401 -------------------------SSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSP 2435
Query: 415 -------PGACCPSCD 423
PG CC C+
Sbjct: 2436 GFELMEAPGECCKKCE 2451
Score = 37.4 bits (85), Expect = 0.11
Identities = 62/267 (23%), Positives = 96/267 (35%), Gaps = 52/267 (19%)
Query: 113 ACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT---TCR--------C 161
ACTA G G + H+ C+++ + N + F + T TCR C
Sbjct: 539 ACTA----KGVMLWGWREHV-----CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHC 589
Query: 162 LTGAVQCQGPSCSELNCLESCTPPGECCPIC---CTEGGSHWEHGQEWTTPGDPCRICRC 218
L G G C + L+ G C P+ C G + E G + C +CR
Sbjct: 590 LEGFAPVDGCGCPDHTFLDE---KGRCVPLAKCSCYHRGLYLEAGDVVVRQEERC-VCR- 644
Query: 219 LEGHIQCRQ-RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCA 277
+G + CRQ R C P + C + S + + +G H C
Sbjct: 645 -DGRLHCRQIRLIGQSCTAPKIHMD---CSNLTALATSKPRALSCQTLAAG--YYHTECV 698
Query: 278 NGSVQCEPLPCPP--VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCS 335
+G V CP + G + + CP C + Y S ++ C C+
Sbjct: 699 SGCV------CPDGLMDDGRGGCVVEKECP----CVHNNDLYSSGAKIKVD----CNTCT 744
Query: 336 CQAGEVSCEEQECPVTPCALPASGRQL 362
C+ G C + C T C++ SG +
Sbjct: 745 CKRGRWVCTQAVCHGT-CSIYGSGHYI 770
Score = 33.9 bits (76), Expect = 1.2
Identities = 57/254 (22%), Positives = 82/254 (32%), Gaps = 58/254 (22%)
Query: 535 CPNDCSGCAFGGKEYPSGADFPHPSDPCR-LCRCLSGNVQCLARRCVPLP---CPEPVLL 590
C D C P+ F + C+ CR LS P+ CP+ L
Sbjct: 555 CNKDVGSC-------PNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFL 607
Query: 591 P--GECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPC----RRCLCLDGSVSCQRLPCPP 644
G C P A C H+ + GD RC+C DG + C+++
Sbjct: 608 DEKGRCVPL--AKCSC--------YHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIG 657
Query: 645 APCAHPRQGPCCPSCDGCLYQGKEFASGERFPS---PTAACHLCLCWEGSVSCEPKACAP 701
C P+ C + S + + T C+C +G +
Sbjct: 658 QSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMD-------- 709
Query: 702 ALCPFPARGDC-----CPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPC 756
RG C CP C + + Y S + + CN CTC G C + C
Sbjct: 710 -----DGRGGCVVEKECP----CVHNNDLYSSGAKI---KVDCNTCTCKRGRWVCTQAVC 757
Query: 757 EPPGCSHPLIPSGH 770
CS + SGH
Sbjct: 758 HGT-CS--IYGSGH 768
Score = 33.5 bits (75), Expect = 1.6
Identities = 45/204 (22%), Positives = 74/204 (36%), Gaps = 39/204 (19%)
Query: 744 CLGGFVTCGRRPCEPPGC-SHPLIPS-GHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS 800
CL GF P + GC H + G C P + C + G+ +G+ + +
Sbjct: 589 CLEGFA-----PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEER--- 640
Query: 801 LCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWC 860
C C++G + C++ C P + S+ R A SC+
Sbjct: 641 -CVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPR-----------ALSCQTL 688
Query: 861 RCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEGSRWVPPDS 914
CV CP L RG C CP C+ + + + G++ + D
Sbjct: 689 AAGYYHTECVSGCVCPD---GLMDDGRGGCVVEKECP----CVHNNDLYSSGAK-IKVD- 739
Query: 915 ACSSCVCHEGVVTCARIQCISSCA 938
C++C C G C + C +C+
Sbjct: 740 -CNTCTCKRGRWVCTQAVCHGTCS 762
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 176 bits (445), Expect = 2e-43
Identities = 148/507 (29%), Positives = 209/507 (41%), Gaps = 92/507 (18%)
Query: 995 QCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWLC 1053
+CP L CP + L Q C C + SN L D C C C
Sbjct: 976 RCPEL--CPRTCPLNMQHQECGSPCTDTCSNPQRAQLCE-----DHCVDGCFCP------ 1022
Query: 1054 IHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGT 1113
P SC + + T G C P+ + P C H GR + G + TC+SC+C G
Sbjct: 1023 -----PGRSCTVLDDITHSG-CLPLGQCP---CTHGGRTYSPGTSFNT-TCSSCTCSGGL 1072
Query: 1114 VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCS 1173
+CQ LP P +C G H T+D +L G CS
Sbjct: 1073 WQCQD-------------------------LPCPGTCSVQGGAHISTYDEKLYDLHGDCS 1107
Query: 1174 YVLAKDCHSGDFSV-------HVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDG 1226
YVL+K C F+V +T+++ V + + GD A+R+ DG V ++
Sbjct: 1108 YVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDG----GDTAIRVQADGGVFLNS 1163
Query: 1227 HPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD--GQSQVEVSVPGSYQGRTCGLCGN 1284
LP + +++ GLQ+L QV V + ++QG+ CGLCGN
Sbjct: 1164 IYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGN 1223
Query: 1285 FNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGRE--VDPCRAAGYRARRE 1342
FN DD G++ + AAF N+W+ C+ R DPC +
Sbjct: 1224 FNQNQADDFTALSGVVEATGAAFANTWKAQAA------CANARNSFEDPC-SLSVENENY 1276
Query: 1343 ANARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCR 1400
A C L +S FSRCH+++ P+PF + C++D C C ++ CLC AL +Y C
Sbjct: 1277 ARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNC---ERSEDCLCAALSSYVHACA 1333
Query: 1401 QAGV-TPTWRGP--TLCVVGCPLER--GFVFDECGPPCPRTCFNQHIPLGELAAHCVRPC 1455
GV WR T + CP + +V D C P C L E C
Sbjct: 1334 AKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCR--------GLSEADVTCSVSF 1385
Query: 1456 VP--GCQCPAGLVEHEA-HCIPPEACP 1479
VP GC CPAG ++A C+P + CP
Sbjct: 1386 VPVDGCTCPAGTFLNDAGACVPAQECP 1412
Score = 161 bits (408), Expect = 4e-39
Identities = 169/639 (26%), Positives = 234/639 (36%), Gaps = 139/639 (21%)
Query: 888 SCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDC 947
+C P CRG L+ + S +VP D C C G C+ P
Sbjct: 1366 ACQPTCRG-LSEADVTCSVS-FVPVDG----CTCPAGTFLNDAGACV---------PAQE 1410
Query: 948 CPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQL 1007
CP C G PGE D VC C L C GC
Sbjct: 1411 CP----CYAHGTVLAPGEVVH---DEGAVCSCTGG-----KLSCLGASLQKSTGC----- 1453
Query: 1008 LPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSE 1067
P SN S G G+E C+T + C+ CP
Sbjct: 1454 -------AAPMVYLDCSNSSAGTPGAECLRS--CHTLDVGCFSTHCVSGCV----CPPGL 1500
Query: 1068 RHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCG 1127
G C P CVH GE VD C +C+C C + C
Sbjct: 1501 VSDGSGGCIAEEDCP---CVHNEATYKPGETIRVD-CNTCTCRNRRWECSHRLCL----- 1551
Query: 1128 PDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSV 1187
+C+A+GD H+ TFDG F+GSC Y+LA+D + GD +
Sbjct: 1552 --------------------GTCVAYGDGHFITFDGDRYSFEGSCEYILAQD-YCGDNTT 1590
Query: 1188 HVT------NDDRGRSGVAWTQEV----------AVLLGDMAVRLLQDGAVTVDGHPVAL 1231
H T N G +G ++ + AV D A +V G L
Sbjct: 1591 HGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASV-GFRQRL 1649
Query: 1232 PFLQ--------------------EPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVP 1271
P LQ +P + G +++ G+ V WD ++ V + +
Sbjct: 1650 PPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLH 1708
Query: 1272 GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDP 1331
Y+GR CGLCGNF+ A +D ++ FGNSW++S P P A DP
Sbjct: 1709 QDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLS----PSCP-DALAPKDP 1763
Query: 1332 CRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDA 1391
C A +R + A +C +L F+ C + V ++ ACV D CAC G + C C A
Sbjct: 1764 CTANPFR-KSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCE-CFCTA 1821
Query: 1392 LEAYASHCRQAGVTPTWRGPTLCVVGCPLER-----GFVFDECGPPCPRTCFNQHIPLGE 1446
+ AYA C AG+ +WR P C + C + + CG PC +TC N
Sbjct: 1822 VAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNP------ 1875
Query: 1447 LAAHCV--RPCVPGC--QCPAG---LVEHEAHCIPPEAC 1478
+ HC+ P + GC +CP E + C+ C
Sbjct: 1876 -SGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGC 1913
Score = 158 bits (399), Expect = 4e-38
Identities = 120/376 (31%), Positives = 169/376 (44%), Gaps = 43/376 (11%)
Query: 1122 SPLSCGPDKAPALSPGSCCP--RCLP-----RPAS----CMAFGDPHYRTFDGRLLHFQG 1170
SP++ GP P L + P R +P PA C +G HY+TFDG + F G
Sbjct: 43 SPIARGPSGVP-LRGATVFPSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPG 101
Query: 1171 SCSYVLAKDCHSG--DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHP 1228
C+YV ++ C + DF++ + R + A T ++ D V L G+V V+GHP
Sbjct: 102 LCNYVFSEHCGAAYEDFNIQLR---RSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHP 158
Query: 1229 VALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGF 1288
V LPF Q +L + +T + A+ GL ++W+ + + + Y +TCGLCG+FNG
Sbjct: 159 VLLPFSQSGVLIQQSSSYTKV-EARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGM 217
Query: 1289 -AQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCR-AAGYRARREANAR 1346
+L L P E FGN ++ + P C P + G+ E
Sbjct: 218 PVVSELLSHNTKLTPME--FGNLQKMDD---PTEQCQDPVPEPPRNCSTGFGICEE---- 268
Query: 1347 CGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTP 1406
+L FS C A+V + AC DLC C + +C+C L Y+ C AG P
Sbjct: 269 --LLHGQLFSGCVALVDVGSYLEACRQDLCFC-EDTDLLSCVCHTLAEYSRQCTHAGGLP 325
Query: 1407 -TWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGL 1465
WRGP C CP + EC PC TC NQ E + C CV GC CP G
Sbjct: 326 QDWRGPDFCPQKCP--NNMQYHECRSPCADTCSNQ-----EHSRACEDHCVAGCFCPEGT 378
Query: 1466 VEH---EAHCIPPEAC 1478
V + C+P C
Sbjct: 379 VLDDIGQTGCVPVSKC 394
Score = 151 bits (382), Expect = 4e-36
Identities = 117/372 (31%), Positives = 157/372 (42%), Gaps = 48/372 (12%)
Query: 1122 SPLSCGPDKA----PALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA 1177
SP GPD PAL+P C +GD HY+TFDG + F G C+YV +
Sbjct: 708 SPKGGGPDLGVQLPPALNPAH-------NGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFS 760
Query: 1178 KDCHSG--DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQ 1235
+ C + DF+V + RG G V+ V +G+V ++G LP+ +
Sbjct: 761 EHCRAAYEDFNVQLR---RGLVGSRPVVTRVVIKAQGLVLEASNGSVLINGQREELPYSR 817
Query: 1236 EPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGF-AQDDLQ 1294
LL VE G + + + L LW+G+ + + Y +TCGLCG+FNG A ++
Sbjct: 818 TGLL-VEQSGDYIKVSIRLVLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFY 876
Query: 1295 GPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSP 1354
L P + FGN ++ P C DP E L
Sbjct: 877 AHNARLTPLQ--FGNLQKLD---GPTEQCP-----DPLPLPAGNCTDEEGICHRTLLGPA 926
Query: 1355 FSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTP-TWRGPTL 1413
F+ CHA+V + AAC DLC C C C Y+ C AG P WR P L
Sbjct: 927 FAECHALVDSTAYLAACAQDLCRC------PTCPCATFVEYSRQCAHAGGQPRNWRCPEL 980
Query: 1414 CVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAG----LVEHE 1469
C CPL ECG PC TC N + A C CV GC CP G +++
Sbjct: 981 CPRTCPL--NMQHQECGSPCTDTCSNP-----QRAQLCEDHCVDGCFCPPGRSCTVLDDI 1033
Query: 1470 AH--CIPPEACP 1479
H C+P CP
Sbjct: 1034 THSGCLPLGQCP 1045
Score = 134 bits (337), Expect = 7e-31
Identities = 132/476 (27%), Positives = 189/476 (39%), Gaps = 86/476 (18%)
Query: 1062 SCPLSERHTPPGSCCPVCR-APTQSCVHQGREVASGERWTVDTCTSCSCMA--------- 1111
+CP S PP S P+ +P C + E WT++ CT C+
Sbjct: 5307 ACPTSP---PPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDP 5363
Query: 1112 ---GTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCL------PRPASCMAFGDPHYRTFD 1162
V C ++ P+ P C C+ P C +G HY TFD
Sbjct: 5364 KPVANVTCVNKHL-PIKVSDPSQPCDFHYECECECVGGRGITPGAGICSMWGGSHYSTFD 5422
Query: 1163 GRLLHFQGSCSYVLAKDCHS--GDFSVHVTNDDRGRSGVAWT-------------QEVAV 1207
G F+G+C+YVL ++ H+ G+ S+++ N S A + + +
Sbjct: 5423 GTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDI 5482
Query: 1208 LLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQP--GLQVLWDGQSQ 1265
+L V ++G + D PV+ F + +L V + G T + P G+ V ++GQ
Sbjct: 5483 VLTVTMVHGKEEGLILFDQIPVSSGFSKNGVL-VSVLGTTTMRVDIPALGVSVTFNGQ-V 5540
Query: 1266 VEVSVPGS-YQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQV----SEGLW-- 1318
+ +P S + T G CG +DD +G S +W V +G W
Sbjct: 5541 FQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAP 5600
Query: 1319 --------PGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAA 1370
P P S+ PC C ++ S F+ CH +VPP PFF A
Sbjct: 5601 TGTPPTASPAAPVSSTPTPTPC---------PPQPLCDLMLSQVFAECHNLVPPGPFFNA 5651
Query: 1371 CVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPT--LCVVGCPLERGFVFDE 1428
C+ D C C +LEAYA CR GV WRG T LC + CP + V+
Sbjct: 5652 CISDHC-----RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTK--VYKP 5704
Query: 1429 CGPPCPRTC--FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHC-IPPEACPQV 1481
CGP P TC NQ L +A GC CP + AH I +ACP V
Sbjct: 5705 CGPIQPATCNSRNQSPQLEGMA--------EGCFCPEDQILFNAHMGICVQACPCV 5752
Score = 93.2 bits (230), Expect = 2e-18
Identities = 102/387 (26%), Positives = 141/387 (36%), Gaps = 88/387 (22%)
Query: 977 CICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALS--NCSEGLLGSE 1034
C+C E + RQC G P GP C C + C
Sbjct: 306 CVCHTLAE-------YSRQCTHAGGLPQDWR---GPDFCPQKCPNNMQYHECRS------ 349
Query: 1035 LAPPDPCY-TCQCQDLTWLCIHQACPELSCPLSERHTPPGS--CCPVCRAPTQSCVHQGR 1091
PC TC Q+ + C CP G C PV + +CV+ G
Sbjct: 350 -----PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKC---ACVYNGA 401
Query: 1092 EVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCM 1151
A G ++ D CT+C+C G CQ C P +C
Sbjct: 402 AYAPGATYSTD-CTNCTCSGGRWSCQEVPC-------------------------PGTCS 435
Query: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGD 1211
G H+ TFDG+ G CSYVL K C S F+V + R G+ ++
Sbjct: 436 VLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLA---ELRRCGLTDSETCL----- 487
Query: 1212 MAVRLLQDGAVTVDGHPVALPFLQEPLL---YVEL----------RGHTVILHAQPGLQV 1258
+V L DGA TV V + E L Y +L R T + AQ L +
Sbjct: 488 KSVTLSLDGAQTV----VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGL 543
Query: 1259 LWDGQ----SQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVS 1314
+ Q Q+ + + +G+TCGLCGNFN DD + G++ + AAF N+++
Sbjct: 544 QLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQ 603
Query: 1315 EGLWPGRPCSAGREVDPCRAAGYRARR 1341
P DPC + A R
Sbjct: 604 AAC----PNIRNSFEDPCSLSVENAPR 626
Score = 81.6 bits (200), Expect = 5e-15
Identities = 110/448 (24%), Positives = 152/448 (33%), Gaps = 72/448 (16%)
Query: 727 LSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPT----CQGCRYHG 782
+S+ P P P LC + V PPG S HC CQ +
Sbjct: 5613 VSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYA 5672
Query: 783 VTTASGETLPDPLDPTCSLC--TCQEGSMRCQKKPCPPALCPHPSPGP--------CFCP 832
+ D T LC TC + P PA C + P CFCP
Sbjct: 5673 ELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCP 5732
Query: 833 -----------VC-HSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCK 880
+C +C G + E +C+ C C G VS +QC PLPC
Sbjct: 5733 EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVS---VQCKPLPCD 5789
Query: 881 LQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSAC--SSCVCHEGVVTCARIQCISSCA 938
Q P C P P++ C ++ C + + C Q S C
Sbjct: 5790 AQGQP-----PPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQ-ESICT 5843
Query: 939 QPRQGPHDCCP--QCSD--CEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRR 994
Q DCCP +C C + G Y G +F PGA PC +C C P+++C
Sbjct: 5844 QEEG---DCCPTFRCRPQLCSYNGTFYGVGATF-PGALPCHMCTCLSGDTQDPTVQCQED 5899
Query: 995 QCPSLVGCPPSQLLPPGPQHCCPTCAEALS--------NCSEGLLGSELAPPDPC--YTC 1044
C + CP CC C + +E + S + D C Y C
Sbjct: 5900 ACNNTT-CPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHV---DNCTVYLC 5955
Query: 1045 QCQDLTWLCIHQ--ACPEL-SCPLSERHTPPGSCCPVC-------RAPTQSCVHQGREVA 1094
+ + L Q +CP++ SC S R T CC C R T HQG E
Sbjct: 5956 EAEGGVHLLTPQPASCPDVSSCRGSLRKT---GCCYSCEEDSCQVRINTTILWHQGCETE 6012
Query: 1095 SGERWTVDTCTSCSCMAGTVRCQSQRCS 1122
+ +C S + + +C+
Sbjct: 6013 VNITFCEGSCPGASKYSAEAQAMQHQCT 6040
Score = 79.0 bits (193), Expect = 3e-14
Identities = 115/457 (25%), Positives = 157/457 (34%), Gaps = 86/457 (18%)
Query: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDC-ILEEEVFVDGESFSHP 500
DS C GT + P ++ P CP P C ++ +VF + + P
Sbjct: 5591 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTP-----CPPQPLCDLMLSQVFAECHNLVPP 5645
Query: 501 RDPCQECRCQEGHAHCQPR---PCPRAPCAHPL---PGTCCPNDCSGCAFGGKEYPSGAD 554
C HC+ R PC L G C +D G G +
Sbjct: 5646 GPFFNACISD----HCRGRLEVPCQSLEAYAELCRARGVC--SDWRGATGGLCDLTCPPT 5699
Query: 555 FPH-PSDPCRLCRCLSGN----VQCLARRCVPLPCPEPVLL----PGECCPQCPA--PAG 603
+ P P + C S N ++ +A C CPE +L G C CP P G
Sbjct: 5700 KVYKPCGPIQPATCNSRNQSPQLEGMAEGCF---CPEDQILFNAHMGICVQACPCVGPDG 5756
Query: 604 CPR-PGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGC 662
P+ PG + C+ C+C +GSVS Q C P PC Q P C + G
Sbjct: 5757 FPKFPGERWVSN----------CQSCVCDEGSVSVQ---CKPLPCDAQGQPPPC-NRPGF 5802
Query: 663 LYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDC----DG 718
+ + A P C+ C + C P ++C GDCCP
Sbjct: 5803 VTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQ--ESICT-QEEGDCCPTFRCRPQL 5859
Query: 719 CEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIP--------SGH 770
C Y G Y FP PC++CTCL G C+ C++ P +G
Sbjct: 5860 CSYNGTFYGVGATFPGAL-PCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQ 5918
Query: 771 CCPTC--QGC-RYHGVTTASGETLPDPLDPTCSLCTCQ-EGSMRCQKKPCPPALCPHPSP 826
CC C C G ET + C++ C+ EG + +P
Sbjct: 5919 CCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLL------------TP 5966
Query: 827 GPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQ 863
P CP SC R+ G SCE CQ
Sbjct: 5967 QPASCPDVSSCRGSLRK-------TGCCYSCEEDSCQ 5996
Score = 76.6 bits (187), Expect = 2e-13
Identities = 71/230 (30%), Positives = 87/230 (37%), Gaps = 29/230 (12%)
Query: 331 CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACV 390
C C C G VS + C PC A G+ P C G + E P T CV
Sbjct: 5769 CQSCVCDEGSVSVQ---CKPLPC--DAQGQP--PPCNRPGFVTVTRPRAENPCCPETVCV 5821
Query: 391 CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC----DSCTYHSQVYANGQNFTDADSPCH 446
C +CPP TQ G CCP+ C+Y+ Y G F A PCH
Sbjct: 5822 CNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGA-LPCH 5880
Query: 447 ACHC-----QDGTVTCSLVDCPPTTCARP---QSGPGQCCPRCPD--CILE--EEVFVDG 494
C C QD TV C C TTC + + GQCC C C+ + V ++
Sbjct: 5881 MCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNE 5940
Query: 495 ESFSHPRDPCQECRCQ-EGHAHC---QPRPCPR-APCAHPLPGTCCPNDC 539
+ D C C+ EG H QP CP + C L T C C
Sbjct: 5941 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSC 5990
Score = 58.9 bits (141), Expect = 4e-08
Identities = 70/276 (25%), Positives = 94/276 (34%), Gaps = 61/276 (22%)
Query: 243 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSV--QCEPLPC----PPVPCRHP 296
G C C +G GE S C C C GSV QC+PLPC P PC P
Sbjct: 5743 GICVQACPCVGPDGFPKFPGERWVSN--CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRP 5800
Query: 297 G-------KIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRC--SCQAGEVS-CEEQ 346
G + CCP ET + C + C G+ S C ++
Sbjct: 5801 GFVTVTRPRAENPCCP---------------ETVCVCNTTTCPQSLPVCPPGQESICTQE 5845
Query: 347 E---CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC 403
E CP C QL C +G + G + P PC C C G + V C
Sbjct: 5846 EGDCCPTFRCR-----PQL---CSYNGTFYGVGATF-PGALPCHMCTCLSGDTQDPTVQC 5896
Query: 404 PPAPCQHPTQP--------PGACCPSC--DSC-TYHSQVYANGQNFTDA---DSPCHACH 449
C + T P G CC C +C T Q + + ++ + + C
Sbjct: 5897 QEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLCE 5956
Query: 450 CQDGT--VTCSLVDCPPTTCARPQSGPGQCCPRCPD 483
+ G +T CP + R CC C +
Sbjct: 5957 AEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEE 5992
Score = 56.6 bits (135), Expect = 2e-07
Identities = 81/306 (26%), Positives = 113/306 (36%), Gaps = 91/306 (29%)
Query: 106 GARWEPDACTACVCQDGAA--HCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLT 163
G RW + C +CVC +G+ C P LP C GQ P C +T
Sbjct: 5762 GERWVSN-CQSCVCDEGSVSVQCKP---LP----CDAQGQ---------PPPCNRPGFVT 5804
Query: 164 GA-VQCQGPSCSELNCLESCT---------PP----------GECCPI------CCTEGG 197
+ + P C E C+ + T PP G+CCP C+ G
Sbjct: 5805 VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNG 5864
Query: 198 SHWEHGQEWTTPGD-PCRICRCLEGH-----IQCRQREC-ASLCP--YPARPLPGTCCPV 248
+ + G T PG PC +C CL G +QC++ C + CP + + + G CC
Sbjct: 5865 TFYGVGA--TFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGE 5922
Query: 249 C--DGCFLNGREHRSGEPV--------GSGDPCSHCRC-ANGSVQC---EPLPCPPV-PC 293
C C G+PV D C+ C A G V +P CP V C
Sbjct: 5923 CVQTACLT-----PDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSC 5977
Query: 294 RHPGKIPGQCCPVC--DGCE---------YQGHQYQSQETFRLQERGLCVRCSCQAGEVS 342
R + G CC C D C+ +QG + + TF G C S + E
Sbjct: 5978 RGSLRKTG-CCYSCEEDSCQVRINTTILWHQGCETEVNITFC---EGSCPGASKYSAEAQ 6033
Query: 343 CEEQEC 348
+ +C
Sbjct: 6034 AMQHQC 6039
Score = 55.1 bits (131), Expect = 5e-07
Identities = 49/213 (23%), Positives = 71/213 (33%), Gaps = 48/213 (22%)
Query: 947 CCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQ 1006
C C +G PGE + C+ C+C+ EG S++C C + PP
Sbjct: 5745 CVQACPCVGPDGFPKFPGERW---VSNCQSCVCD---EGSVSVQCKPLPCDAQGQPPPCN 5798
Query: 1007 -------LLPPGPQHCCP--TCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQA 1057
P CCP C + C + L + PP C ++
Sbjct: 5799 RPGFVTVTRPRAENPCCPETVCVCNTTTCPQSL---PVCPPGQESICTQEE--------- 5846
Query: 1058 CPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWT-VDTCTSCSCMAG---- 1112
G CCP R Q C + G G + C C+C++G
Sbjct: 5847 ---------------GDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQD 5891
Query: 1113 -TVRCQSQRCSPLSCGPDKAPALSPGSCCPRCL 1144
TV+CQ C+ +C G CC C+
Sbjct: 5892 PTVQCQEDACNNTTCPQGFEYKRVAGQCCGECV 5924
Score = 50.4 bits (119), Expect = 1e-05
Identities = 69/283 (24%), Positives = 93/283 (32%), Gaps = 50/283 (17%)
Query: 97 WGLGRAWPEGARWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPD 154
W L + P+ A D CTA + A C H P C + E D
Sbjct: 1748 WKLSPSCPD-ALAPKDPCTANPFRKSWAQKQCSI-LHGPTFAACRSQVDSTKYYEACVND 1805
Query: 155 ACTT-----CRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCT----EGGSHWEHGQE 205
AC C C AV +C + S P + CP+ C GG W +
Sbjct: 1806 ACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTP-DTCPLFCDFYNPHGGCEWHY--- 1861
Query: 206 WTTPGDPC-RICRCLEGHIQCRQ---RECASLCPYPARPLPGT----CCPVCDGCF-LNG 256
G PC + CR GH C CP P++P C C GC+ +G
Sbjct: 1862 -QPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-PSQPFFNEDQMKCVAQC-GCYDKDG 1918
Query: 257 REHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQ 316
+ G V + + C C C +QC C C Y+
Sbjct: 1919 NYYDVGARVPTAENCQSCNCTPSGIQC-----------------AHSLEACT-CTYEDRT 1960
Query: 317 YQSQETFRLQERGL--CVRCSCQA-GEVSCEEQECPVTPCALP 356
Y Q+ GL C+ C + G + + CP TP P
Sbjct: 1961 YSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTP 2003
Score = 46.6 bits (109), Expect = 2e-04
Identities = 57/236 (24%), Positives = 72/236 (30%), Gaps = 66/236 (27%)
Query: 404 PPAPCQHPT-QPPGACCPSCDSCT--YHSQVYANGQNFTDADSPCHACH-----CQDGTV 455
P CQ P +PP C C H Q+++ D S AC C+D
Sbjct: 244 PTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED--- 300
Query: 456 TCSLVDCPPTTCAR-----------PQS--GPGQCCPRCPDCILEEEVFVDGESFSHPRD 502
L+ C T A PQ GP C +CP+ + E R
Sbjct: 301 -TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHEC----------RS 349
Query: 503 PCQE-CRCQEGHAHCQPRP-----CPRAPCAHPLPGT-CCPNDCSGCAFGGKEYPSGADF 555
PC + C QE C+ CP + T C P C + G Y GA +
Sbjct: 350 PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 556 PHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAH 611
S C C C G C + P P C G AH
Sbjct: 410 ---STDCTNCTCSGGRWSC---------------------QEVPCPGTCSVLGGAH 441
Score = 45.4 bits (106), Expect = 4e-04
Identities = 36/113 (31%), Positives = 47/113 (41%), Gaps = 22/113 (19%)
Query: 105 EGARWEPDACTA-CVCQDGAA--HCGPQAHLPHCR-GCSQNGQTYGNGETFSPDACTTCR 160
E +R D C A C C +G G +P + C NG Y G T+S D CT C
Sbjct: 359 EHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-CTNCT 417
Query: 161 CLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWE--HGQEWTTPGD 211
C G CQ C PG C + GG+H+ G+++T GD
Sbjct: 418 CSGGRWSCQEVPC-----------PGTCSVL----GGAHFSTFDGKQYTVHGD 455
Score = 44.3 bits (103), Expect = 0.001
Identities = 43/148 (29%), Positives = 50/148 (33%), Gaps = 30/148 (20%)
Query: 156 CTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWT-TPGDPCR 214
C TC C T + C+ E CP C H E G T T +P R
Sbjct: 950 CPTCPCATFVEYSR--QCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQR 1007
Query: 215 ICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------------CFLNGREHRS 261
C E H C C P PG C V D C GR +
Sbjct: 1008 AQLC-EDH-------CVDGCFCP----PGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP 1055
Query: 262 GEPVGSGDPCSHCRCANGSVQCEPLPCP 289
G + CS C C+ G QC+ LPCP
Sbjct: 1056 GTSFNT--TCSSCTCSGGLWQCQDLPCP 1081
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/173 (26%), Positives = 58/173 (33%), Gaps = 33/173 (19%)
Query: 89 CH-----PASPQCWGL--GRAWPEGARWEPDACTACVCQD------GAAHCGPQAHLPHC 135
CH PA +C L A+ + C C C AH G Q C
Sbjct: 918 CHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRC 977
Query: 136 -----RGCSQNGQTYGNGETFS-----PDACTTCR--CLTGAVQCQGPSCSELNCL--ES 181
R C N Q G + P C C+ G G SC+ L+ +
Sbjct: 978 PELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG 1037
Query: 182 CTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLC 234
C P G+C CT GG + G + T C C C G QC+ C C
Sbjct: 1038 CLPLGQCP---CTHGGRTYSPGTSFNTT---CSSCTCSGGLWQCQDLPCPGTC 1084
Score = 42.4 bits (98), Expect = 0.003
Identities = 38/162 (23%), Positives = 58/162 (35%), Gaps = 28/162 (17%)
Query: 304 CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLC 363
CP C + + Q C + ++ + QEC +PC S Q
Sbjct: 950 CPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECG-SPCTDTCSNPQRA 1008
Query: 364 PACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD 423
CE + +G + P GR CT D + G + P G C
Sbjct: 1009 QLCE---DHCVDGC-FCPPGRSCTVL---DDITHSGCL------------PLGQC----- 1044
Query: 424 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPT 465
CT+ + Y+ G +F ++ C +C C G C + CP T
Sbjct: 1045 PCTHGGRTYSPGTSF---NTTCSSCTCSGGLWQCQDLPCPGT 1083
Score = 41.2 bits (95), Expect = 0.008
Identities = 53/204 (25%), Positives = 72/204 (35%), Gaps = 33/204 (16%)
Query: 632 DGSVSCQR-LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACH--LCLCW 688
D + CQ +P PP C+ G C G L+ G + S AC LC C
Sbjct: 243 DPTEQCQDPVPEPPRNCS-TGFGICEELLHGQLFSG--CVALVDVGSYLEACRQDLCFCE 299
Query: 689 EGSV-SCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGG 747
+ + SC A G D G ++ + +N ++ + R PC
Sbjct: 300 DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCA------- 352
Query: 748 FVTCGR----RPCEPPGCSHPLIPSGH---------CCPTCQ-GCRYHGVTTASGETLPD 793
TC R CE + P G C P + C Y+G A G T
Sbjct: 353 -DTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY-- 409
Query: 794 PLDPTCSLCTCQEGSMRCQKKPCP 817
C+ CTC G CQ+ PCP
Sbjct: 410 --STDCTNCTCSGGRWSCQEVPCP 431
Score = 41.2 bits (95), Expect = 0.008
Identities = 47/179 (26%), Positives = 63/179 (35%), Gaps = 37/179 (20%)
Query: 389 CVCQDGVPKC--GAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH 446
C G+P+ G CP C + Q P D+C+ N ++ + C
Sbjct: 318 CTHAGGLPQDWRGPDFCPQK-CPNNMQYHECRSPCADTCS-------NQEHSRACEDHCV 369
Query: 447 A-CHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQ 505
A C C +GTV L D T C P C C+ + G ++S C
Sbjct: 370 AGCFCPEGTV---LDDIGQTGCV-----PVSKCA----CVYNGAAYAPGATYS---TDCT 414
Query: 506 ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP-NDCSGCAFGGKEYPSGADFPHP-SDPC 562
C C G CQ PC PGTC F GK+Y D + + PC
Sbjct: 415 NCTCSGGRWSCQEVPC---------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPC 464
Score = 40.4 bits (93), Expect = 0.013
Identities = 56/226 (24%), Positives = 70/226 (30%), Gaps = 48/226 (21%)
Query: 597 QCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPC- 655
QCP P P A + +E C R L C L A A Q C
Sbjct: 899 QCPDPLPLP---AGNCTDEEGI------CHRTLLGPAFAECHALVDSTAYLAACAQDLCR 949
Query: 656 CPSCDGCLY--QGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCC 713
CP+C + ++ A P LC P CP + C
Sbjct: 950 CPTCPCATFVEYSRQCAHAGGQPRNWRCPELC---------------PRTCPLNMQHQEC 994
Query: 714 --PDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHC 771
P D C + L D C C G GC +P G C
Sbjct: 995 GSPCTDTCSNPQRAQLCEDHCVDG------CFCPPGRSCTVLDDITHSGC----LPLGQC 1044
Query: 772 CPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCP 817
C + G T + G + + TCS CTC G +CQ PCP
Sbjct: 1045 -----PCTHGGRTYSPGTSF----NTTCSSCTCSGGLWQCQDLPCP 1081
Score = 40.4 bits (93), Expect = 0.013
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 24/194 (12%)
Query: 761 CSHPL-IPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPA 819
C PL +P+G+C +G + + + +D T L C + RC PC
Sbjct: 900 CPDPLPLPAGNCTDE-EGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATF 958
Query: 820 L-----CPHPSPGP--CFCP-VCHSCLSQGREHQD-GEEFEGPAGSCEWCRCQAGQVSCV 870
+ C H P CP +C +HQ+ G + + R Q + CV
Sbjct: 959 VEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQ--RAQLCEDHCV 1016
Query: 871 R-LQCPP-LPCKL--QVTERGSCCP--RCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEG 924
CPP C + +T G C P +C C G + G+ + ++ CSSC C G
Sbjct: 1017 DGCFCPPGRSCTVLDDITHSG-CLPLGQCP-CTHGGRTYSPGTSF---NTTCSSCTCSGG 1071
Query: 925 VVTCARIQCISSCA 938
+ C + C +C+
Sbjct: 1072 LWQCQDLPCPGTCS 1085
Score = 38.1 bits (87), Expect = 0.065
Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 11/113 (9%)
Query: 536 PNDCSGCAFGGKEYPSGADFPHPSDPCR-LCRCLSGNVQCLARRCVPLPCPEPVLLPG-- 592
P D G F ++ P+ + PC C + C CPE +L
Sbjct: 325 PQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIG 384
Query: 593 --ECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 643
C P + C GAA+A Y + C C C G SCQ +PCP
Sbjct: 385 QTGCVPV--SKCACVYNGAAYAPGATYSTD----CTNCTCSGGRWSCQEVPCP 431
Score = 38.1 bits (87), Expect = 0.065
Identities = 45/168 (26%), Positives = 60/168 (35%), Gaps = 29/168 (17%)
Query: 1329 VDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACL 1388
VD C+ R EA+ C V P C P F + D AC P
Sbjct: 1364 VDACQPT-CRGLSEADVTCSV-SFVPVDGC--TCPAGTF----LNDAGACVPAQECPCYA 1415
Query: 1389 CDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERG------FVFDEC--------GPPCP 1434
+ A G + G L +G L++ V+ +C G C
Sbjct: 1416 HGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECL 1475
Query: 1435 RTCFNQHIPLGELAAHCVRPCVPGCQCPAGLV-EHEAHCIPPEACPQV 1481
R+C + +G + HCV GC CP GLV + CI E CP V
Sbjct: 1476 RSCHT--LDVGCFSTHCVS----GCVCPPGLVSDGSGGCIAEEDCPCV 1517
Score = 37.7 bits (86), Expect = 0.084
Identities = 87/386 (22%), Positives = 115/386 (29%), Gaps = 97/386 (25%)
Query: 909 WVPPDSACSSCVCHEGVV-TCARIQCISSCAQPRQGP----------------HDCCPQ- 950
W+ PDS C G T + +SS P P H+ P
Sbjct: 5587 WLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPG 5646
Query: 951 -----CSDCEHEGRKYEPGESFQPGADPCE---VC-------------ICEP----QPEG 985
C GR P +S + A+ C VC C P +P G
Sbjct: 5647 PFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCG 5706
Query: 986 P--PSLRCHRRQCPSLVG------CPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAP 1037
P P+ R Q P L G CP Q+L C + G + P
Sbjct: 5707 PIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCV--------GPDGFP 5758
Query: 1038 PDP-------CYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQG 1090
P C +C C + + + C L C ++ PP C G
Sbjct: 5759 KFPGERWVSNCQSCVCDEGS---VSVQCKPLPCD-AQGQPPP-------------CNRPG 5801
Query: 1091 REVASGERWTVDTCTSCSCMAGTVRCQSQR--CSPLSCGPDKAPALSPGSCCPRCLPRPA 1148
+ R C C+ T C C P G + G CCP RP
Sbjct: 5802 FVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPP---GQESICTQEEGDCCPTFRCRPQ 5858
Query: 1149 SCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDF---SVHVTNDDRGRSGVAWTQEV 1205
C G TF G F G+ + C SGD +V D + E
Sbjct: 5859 LCSYNG-----TFYGVGATFPGALPCHMC-TCLSGDTQDPTVQCQEDACNNTTCPQGFEY 5912
Query: 1206 AVLLGDMAVRLLQDGAVTVDGHPVAL 1231
+ G +Q +T DG PV L
Sbjct: 5913 KRVAGQCCGECVQTACLTPDGQPVQL 5938
Score = 37.0 bits (84), Expect = 0.14
Identities = 41/147 (27%), Positives = 48/147 (32%), Gaps = 37/147 (25%)
Query: 274 CRC---ANGSVQCEPLPCPPVPCRHPGKIPGQC----------CPVCDGCEYQGHQYQSQ 320
C C A S QC P R P P +C P D C Q H
Sbjct: 306 CVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHS---- 361
Query: 321 ETFRLQERGLCVRCSCQAGEVSCE--EQEC-PVTPCALPASGRQLCPACELDGEEFAEGV 377
R E C C G V + + C PV+ CA C +G +A G
Sbjct: 362 ---RACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA-----------CVYNGAAYAPGA 407
Query: 378 QWEPDGRPCTACVCQDGVPKCGAVLCP 404
+ D CT C C G C V CP
Sbjct: 408 TYSTD---CTNCTCSGGRWSCQEVPCP 431
Score = 37.0 bits (84), Expect = 0.14
Identities = 40/145 (27%), Positives = 50/145 (34%), Gaps = 14/145 (9%)
Query: 386 CTACVCQDGVPKCGAVLCPPAPCQHPT-QPPGACCPSC--DSCTYHSQVYANGQNFTDAD 442
C +C+ C + C H QP CP +C + Q G TD
Sbjct: 943 CAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 1002
Query: 443 S-PCHACHCQDGTVTCSLVDCPP--TTCARPQSGPGQCCP--RCPDCILEEEVFVDGESF 497
S P A C+D V CPP + C P +CP C + G SF
Sbjct: 1003 SNPQRAQLCEDHCVDGCF--CPPGRSCTVLDDITHSGCLPLGQCP-CTHGGRTYSPGTSF 1059
Query: 498 SHPRDPCQECRCQEGHAHCQPRPCP 522
+ C C C G CQ PCP
Sbjct: 1060 N---TTCSSCTCSGGLWQCQDLPCP 1081
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/212 (25%), Positives = 66/212 (31%), Gaps = 62/212 (29%)
Query: 789 ETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCP-HP-----------SPGPCFCPVCHS 836
E PDPL CT +EG C + PA H + C CP C
Sbjct: 898 EQCPDPLPLPAGNCTDEEGI--CHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC-P 954
Query: 837 CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCP----- 891
C + F + C Q C L P +Q E GS C
Sbjct: 955 CAT----------FVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 1004
Query: 892 --RCRGCLAHGEEHPEGSRWVPPDSACSSC--VCHEGVVTCARIQCISSCAQPRQGPHDC 947
R + C E+H + PP +C+ + H G + P
Sbjct: 1005 PQRAQLC----EDHCVDGCFCPPGRSCTVLDDITHSGCL-----------------PLGQ 1043
Query: 948 CPQCSDCEHEGRKYEPGESFQPGADPCEVCIC 979
CP C H GR Y PG SF C C C
Sbjct: 1044 CP----CTHGGRTYSPGTSFN---TTCSSCTC 1068
Score = 35.8 bits (81), Expect = 0.32
Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 5/50 (10%)
Query: 303 CCPVCD-GCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVT 351
C PV C Y G Y T+ C C+C G SC+E CP T
Sbjct: 388 CVPVSKCACVYNGAAYAPGATYSTD----CTNCTCSGGRWSCQEVPCPGT 433
Score = 35.8 bits (81), Expect = 0.32
Identities = 50/191 (26%), Positives = 57/191 (29%), Gaps = 61/191 (31%)
Query: 437 NFTDADSPCHACHCQDGTVTC-SLVDCPPTTCARPQSGPGQC-CPRCPDCILEEEVFVDG 494
N TD + CH C +LVD A Q C CP CP E
Sbjct: 910 NCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQD---LCRCPTCPCATFVEYSRQCA 966
Query: 495 ESFSHPRDPCQECRCQEGHAHCQPRPCP----RAPCAHPLPGTC--------CPNDC--- 539
+ PR+ RC E PR CP C P TC C + C
Sbjct: 967 HAGGQPRN----WRCPE----LCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDG 1018
Query: 540 -----------------SGC--------AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQC 574
SGC GG+ Y G F + C C C G Q
Sbjct: 1019 CFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF---NTTCSSCTCSGGLWQ- 1074
Query: 575 LARRCVPLPCP 585
C LPCP
Sbjct: 1075 ----CQDLPCP 1081
Score = 35.0 bits (79), Expect = 0.55
Identities = 49/219 (22%), Positives = 69/219 (31%), Gaps = 56/219 (25%)
Query: 797 PTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE-------- 848
PT + C Q S + + C C S G C C C + + + D
Sbjct: 1784 PTFAACRSQVDSTKYYEA-CVNDACACDSGGDCEC-FCTAVAAYAQACHDAGLCVSWRTP 1841
Query: 849 -------EFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRC-------- 893
+F P G CEW G + P C + + C P+C
Sbjct: 1842 DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFN 1901
Query: 894 ---RGCLAH-------GEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQG 943
C+A G + G+R VP C SC C T + IQC S
Sbjct: 1902 EDQMKCVAQCGCYDKDGNYYDVGAR-VPTAENCQSCNC-----TPSGIQCAHSL------ 1949
Query: 944 PHDCCPQCSDCEHEGRKYEPGE---SFQPGADPCEVCIC 979
+ C +E R Y + + G C + IC
Sbjct: 1950 ------EACTCTYEDRTYSYQDVIYNTTDGLGACLIAIC 1982
Score = 34.3 bits (77), Expect = 0.93
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 245 CCPVCD-GCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
C PV C NG + G + C++C C+ G C+ +PCP
Sbjct: 388 CVPVSKCACVYNGAAYAPGATYSTD--CTNCTCSGGRWSCQEVPCP 431
Score = 33.5 bits (75), Expect = 1.6
Identities = 30/127 (23%), Positives = 46/127 (36%), Gaps = 28/127 (22%)
Query: 818 PALCPHPSPG-----PCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRL 872
P CP P C P +C +Q EH E AG C C G V
Sbjct: 331 PDFCPQKCPNNMQYHECRSPCADTCSNQ--EHSRACEDHCVAG----CFCPEGTV----- 379
Query: 873 QCPPLPCKLQVTERGSCCPRCR-GCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARI 931
L + C P + C+ +G + G+ + + C++C C G +C +
Sbjct: 380 --------LDDIGQTGCVPVSKCACVYNGAAYAPGATY---STDCTNCTCSGGRWSCQEV 428
Query: 932 QCISSCA 938
C +C+
Sbjct: 429 PCPGTCS 435
Score = 32.3 bits (72), Expect = 3.5
Identities = 45/189 (23%), Positives = 53/189 (28%), Gaps = 67/189 (35%)
Query: 117 CVCQDG-----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP 171
C C G A C P P C +G GE D C C G + C G
Sbjct: 1391 CTCPAGTFLNDAGACVPAQECP----CYAHGTVLAPGEVVH-DEGAVCSCTGGKLSCLGA 1445
Query: 172 SCSE----------LNCLESC--TPPGECCPICCT------------------------E 195
S + L+C S TP EC C T
Sbjct: 1446 SLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGS 1505
Query: 196 GGSHWE------HGQEWTTPGDP----CRICRCLEGHIQCRQRECASLCPYPARPLPGTC 245
GG E H + PG+ C C C +C R C GTC
Sbjct: 1506 GGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCL-----------GTC 1554
Query: 246 CPVCDGCFL 254
DG F+
Sbjct: 1555 VAYGDGHFI 1563
Score = 32.0 bits (71), Expect = 4.6
Identities = 40/154 (25%), Positives = 52/154 (33%), Gaps = 25/154 (16%)
Query: 84 LESCECHPA---SPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQ 140
L SC CH S QC G P+ R PD C C CR S
Sbjct: 303 LLSCVCHTLAEYSRQCTHAG-GLPQDWRG-PDFCPQ--------KCPNNMQYHECR--SP 350
Query: 141 NGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHW 200
T N E AC C+ G +G ++ C P +C C G+ +
Sbjct: 351 CADTCSNQE--HSRACED-HCVAGCFCPEGTVLDDIG-QTGCVPVSKCA---CVYNGAAY 403
Query: 201 EHGQEWTTPGDPCRICRCLEGHIQCRQRECASLC 234
G ++T C C C G C++ C C
Sbjct: 404 APGATYSTD---CTNCTCSGGRWSCQEVPCPGTC 434
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 176 bits (445), Expect = 2e-43
Identities = 148/507 (29%), Positives = 209/507 (41%), Gaps = 92/507 (18%)
Query: 995 QCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWLC 1053
+CP L CP + L Q C C + SN L D C C C
Sbjct: 320 RCPEL--CPRTCPLNMQHQECGSPCTDTCSNPQRAQLCE-----DHCVDGCFCP------ 366
Query: 1054 IHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGT 1113
P SC + + T G C P+ + P C H GR + G + TC+SC+C G
Sbjct: 367 -----PGRSCTVLDDITHSG-CLPLGQCP---CTHGGRTYSPGTSFNT-TCSSCTCSGGL 416
Query: 1114 VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCS 1173
+CQ LP P +C G H T+D +L G CS
Sbjct: 417 WQCQD-------------------------LPCPGTCSVQGGAHISTYDEKLYDLHGDCS 451
Query: 1174 YVLAKDCHSGDFSV-------HVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDG 1226
YVL+K C F+V +T+++ V + + GD A+R+ DG V ++
Sbjct: 452 YVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDG----GDTAIRVQADGGVFLNS 507
Query: 1227 HPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD--GQSQVEVSVPGSYQGRTCGLCGN 1284
LP + +++ GLQ+L QV V + ++QG+ CGLCGN
Sbjct: 508 IYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGN 567
Query: 1285 FNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGRE--VDPCRAAGYRARRE 1342
FN DD G++ + AAF N+W+ C+ R DPC +
Sbjct: 568 FNQNQADDFTALSGVVEATGAAFANTWKAQAA------CANARNSFEDPC-SLSVENENY 620
Query: 1343 ANARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCR 1400
A C L +S FSRCH+++ P+PF + C++D C C ++ CLC AL +Y C
Sbjct: 621 ARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNC---ERSEDCLCAALSSYVHACA 677
Query: 1401 QAGV-TPTWRGP--TLCVVGCPLER--GFVFDECGPPCPRTCFNQHIPLGELAAHCVRPC 1455
GV WR T + CP + +V D C P C L E C
Sbjct: 678 AKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCR--------GLSEADVTCSVSF 729
Query: 1456 VP--GCQCPAGLVEHEA-HCIPPEACP 1479
VP GC CPAG ++A C+P + CP
Sbjct: 730 VPVDGCTCPAGTFLNDAGACVPAQECP 756
Score = 171 bits (433), Expect = 5e-42
Identities = 164/609 (26%), Positives = 233/609 (38%), Gaps = 113/609 (18%)
Query: 888 SCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDC 947
+C P CRG L+ + S +VP D C C G C+ P
Sbjct: 710 ACQPTCRG-LSEADVTCSVS-FVPVDG----CTCPAGTFLNDAGACV---------PAQE 754
Query: 948 CPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQL 1007
CP C G PGE D VC C L C GC
Sbjct: 755 CP----CYAHGTVLAPGEVVH---DEGAVCSCTGG-----KLSCLGASLQKSTGC----- 797
Query: 1008 LPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSE 1067
P SN S G G+E C+T + C+ CP
Sbjct: 798 -------AAPMVYLDCSNSSAGTPGAECLRS--CHTLDVGCFSTHCVSGCV----CPPGL 844
Query: 1068 RHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCG 1127
G C P CVH GE VD C +C+C C + C
Sbjct: 845 VSDGSGGCIAEEDCP---CVHNEATYKPGETIRVD-CNTCTCRNRRWECSHRLCL----- 895
Query: 1128 PDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSV 1187
+C+A+GD H+ TFDG F+GSC Y+LA+D + GD +
Sbjct: 896 --------------------GTCVAYGDGHFITFDGDRYSFEGSCEYILAQD-YCGDNTT 934
Query: 1188 HVT------NDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYV 1241
H T N G +G ++ + + + + +LQ+G VA +P +
Sbjct: 935 HGTFRIVTENIPCGTTGTTCSKAIKLFVESYEL-ILQEGTFKA----VARGPGGDPPYKI 989
Query: 1242 ELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL 1301
G +++ G+ V WD ++ V + + Y+GR CGLCGNF+ A +D ++
Sbjct: 990 RYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVV 1048
Query: 1302 PSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAV 1361
FGNSW++S P P A DPC A +R + A +C +L F+ C +
Sbjct: 1049 GDALEFGNSWKLS----PSCP-DALAPKDPCTANPFR-KSWAQKQCSILHGPTFAACRSQ 1102
Query: 1362 VPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLE 1421
V ++ ACV D CAC G + C C A+ AYA C AG+ +WR P C + C
Sbjct: 1103 VDSTKYYEACVNDACACDSGGDCE-CFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFY 1161
Query: 1422 R-----GFVFDECGPPCPRTCFNQHIPLGELAAHCV--RPCVPGC--QCPAG---LVEHE 1469
+ + CG PC +TC N + HC+ P + GC +CP E +
Sbjct: 1162 NPHGGCEWHYQPCGAPCLKTCRNP-------SGHCLVDLPGLEGCYPKCPPSQPFFNEDQ 1214
Query: 1470 AHCIPPEAC 1478
C+ C
Sbjct: 1215 MKCVAQCGC 1223
Score = 149 bits (375), Expect = 3e-35
Identities = 108/340 (31%), Positives = 147/340 (43%), Gaps = 37/340 (10%)
Query: 1150 CMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG--DFSVHVTNDDRGRSGVAWTQEVAV 1207
C +GD HY+TFDG + F G C+YV ++ C + DF+V + RG G V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLR---RGLVGSRPVVTRVV 133
Query: 1208 LLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVE 1267
+ V +G+V ++G LP+ + LL VE G + + + L LW+G+
Sbjct: 134 IKAQGLVLEASNGSVLINGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNGEDSAL 192
Query: 1268 VSVPGSYQGRTCGLCGNFNGF-AQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAG 1326
+ + Y +TCGLCG+FNG A ++ L P + FGN ++ P C
Sbjct: 193 LELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLD---GPTEQCP-- 245
Query: 1327 REVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADA 1386
DP E L F+ CHA+V + AAC DLC C
Sbjct: 246 ---DPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRC------PT 296
Query: 1387 CLCDALEAYASHCRQAGVTP-TWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG 1445
C C Y+ C AG P WR P LC CPL ECG PC TC N
Sbjct: 297 CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPL--NMQHQECGSPCTDTCSNP----- 349
Query: 1446 ELAAHCVRPCVPGCQCPAG----LVEHEAH--CIPPEACP 1479
+ A C CV GC CP G +++ H C+P CP
Sbjct: 350 QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCP 389
Score = 135 bits (341), Expect = 2e-31
Identities = 130/460 (28%), Positives = 187/460 (40%), Gaps = 69/460 (15%)
Query: 1062 SCPLSERHTPPGSCCPVCR-APTQSCVHQGREVASGERWTVDTCTSCSCMAGT--VRCQS 1118
+CP S PP S P+ +P C + E WT++ CT C+ V
Sbjct: 4988 ACPTSP---PPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDP 5044
Query: 1119 QRCSPLSCGPDKAP--ALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVL 1176
+ + ++C P P C C +G HY TFDG F+G+C+YVL
Sbjct: 5045 KPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVL 5104
Query: 1177 AKDCHS--GDFSVHVTNDDRGRSGVAWT-----------QEVAVLLGDMAVRLLQDGAVT 1223
++ H+ G+ S+++ N S A + + ++L V ++G +
Sbjct: 5105 MREIHARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLIL 5164
Query: 1224 VDGHPVALPFLQEPLLYVELRGHTVILHAQP--GLQVLWDGQSQVEVSVPGS-YQGRTCG 1280
D PV+ F + +L V + G T + P G+ V ++GQ + +P S + T G
Sbjct: 5165 FDQIPVSSGFSKNGVL-VSVLGTTTMRVDIPALGVSVTFNGQ-VFQARLPYSLFHNNTEG 5222
Query: 1281 LCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQV----SEGLW----------PGRPCSAG 1326
CG +DD +G S +W V +G W P P S+
Sbjct: 5223 QCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSST 5282
Query: 1327 REVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADA 1386
PC C ++ S F+ CH +VPP PFF AC+ D C
Sbjct: 5283 PTPTPC---------PPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC-----RGRLE 5328
Query: 1387 CLCDALEAYASHCRQAGVTPTWRGPT--LCVVGCPLERGFVFDECGPPCPRTC--FNQHI 1442
C +LEAYA CR GV WRG T LC + CP + V+ CGP P TC NQ
Sbjct: 5329 VPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTK--VYKPCGPIQPATCNSRNQSP 5386
Query: 1443 PLGELAAHCVRPCVPGCQCPAGLVEHEAHC-IPPEACPQV 1481
L +A GC CP + AH I +ACP V
Sbjct: 5387 QLEGMA--------EGCFCPEDQILFNAHMGICVQACPCV 5418
Score = 86.7 bits (213), Expect = 2e-16
Identities = 123/504 (24%), Positives = 167/504 (33%), Gaps = 94/504 (18%)
Query: 727 LSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPT----CQGCRYHG 782
+S+ P P P LC + V PPG S HC CQ +
Sbjct: 5279 VSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYA 5338
Query: 783 VTTASGETLPDPLDPTCSLC--TCQEGSMRCQKKPCPPALCPHPSPGP--------CFCP 832
+ D T LC TC + P PA C + P CFCP
Sbjct: 5339 ELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCP 5398
Query: 833 -----------VC-HSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCK 880
+C +C G + E +C+ C C G VS +QC PLPC
Sbjct: 5399 EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVS---VQCKPLPCD 5455
Query: 881 LQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSAC--SSCVCHEGVVTCARIQCISSCA 938
Q P C P P++ C ++ C + + C Q S C
Sbjct: 5456 AQGQP-----PPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQ-ESICT 5509
Query: 939 QPRQGPHDCCP--QCSD--CEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRR 994
Q DCCP +C C + G Y G +F PGA PC +C C P+++C
Sbjct: 5510 QEEG---DCCPTFRCRPQLCSYNGTFYGVGATF-PGALPCHMCTCLSGDTQDPTVQCQED 5565
Query: 995 QCPSLVGCPPSQLLPPGPQHCCPTCAEALS--------NCSEGLLGSELAPPDPC--YTC 1044
C + CP CC C + +E + S + D C Y C
Sbjct: 5566 ACNNTT-CPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHV---DNCTVYLC 5621
Query: 1045 QCQDLTWLCIHQ--ACPEL-SCPLSERHTPPGSCCPVC-------RAPTQSCVHQGREVA 1094
+ + L Q +CP++ SC S R T CC C R T HQG E
Sbjct: 5622 EAEGGVHLLTPQPASCPDVSSCRGSLRKT---GCCYSCEEDSCQVRINTTILWHQGCETE 5678
Query: 1095 SGERWTVDTCTSCSCMAGTVRCQSQRCS------------PLSCGPDKA-----PALSPG 1137
+ +C S + + +C+ PL C A +
Sbjct: 5679 VNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILHTYTHVDEC 5738
Query: 1138 SCCPRCLPRPASCMAFGDPHYRTF 1161
C P C+P P PH R F
Sbjct: 5739 GCTPFCVPAP-----MAPPHTRGF 5757
Score = 79.0 bits (193), Expect = 3e-14
Identities = 115/457 (25%), Positives = 157/457 (34%), Gaps = 86/457 (18%)
Query: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDC-ILEEEVFVDGESFSHP 500
DS C GT + P ++ P CP P C ++ +VF + + P
Sbjct: 5257 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTP-----CPPQPLCDLMLSQVFAECHNLVPP 5311
Query: 501 RDPCQECRCQEGHAHCQPR---PCPRAPCAHPL---PGTCCPNDCSGCAFGGKEYPSGAD 554
C HC+ R PC L G C +D G G +
Sbjct: 5312 GPFFNACISD----HCRGRLEVPCQSLEAYAELCRARGVC--SDWRGATGGLCDLTCPPT 5365
Query: 555 FPH-PSDPCRLCRCLSGN----VQCLARRCVPLPCPEPVLL----PGECCPQCPA--PAG 603
+ P P + C S N ++ +A C CPE +L G C CP P G
Sbjct: 5366 KVYKPCGPIQPATCNSRNQSPQLEGMAEGCF---CPEDQILFNAHMGICVQACPCVGPDG 5422
Query: 604 CPR-PGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGC 662
P+ PG + C+ C+C +GSVS Q C P PC Q P C + G
Sbjct: 5423 FPKFPGERWVSN----------CQSCVCDEGSVSVQ---CKPLPCDAQGQPPPC-NRPGF 5468
Query: 663 LYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDC----DG 718
+ + A P C+ C + C P ++C GDCCP
Sbjct: 5469 VTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQ--ESICT-QEEGDCCPTFRCRPQL 5525
Query: 719 CEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIP--------SGH 770
C Y G Y FP PC++CTCL G C+ C++ P +G
Sbjct: 5526 CSYNGTFYGVGATFPGAL-PCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQ 5584
Query: 771 CCPTC--QGC-RYHGVTTASGETLPDPLDPTCSLCTCQ-EGSMRCQKKPCPPALCPHPSP 826
CC C C G ET + C++ C+ EG + +P
Sbjct: 5585 CCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLL------------TP 5632
Query: 827 GPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQ 863
P CP SC R+ G SCE CQ
Sbjct: 5633 QPASCPDVSSCRGSLRK-------TGCCYSCEEDSCQ 5662
Score = 76.6 bits (187), Expect = 2e-13
Identities = 71/230 (30%), Positives = 87/230 (37%), Gaps = 29/230 (12%)
Query: 331 CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACV 390
C C C G VS + C PC A G+ P C G + E P T CV
Sbjct: 5435 CQSCVCDEGSVSVQ---CKPLPC--DAQGQP--PPCNRPGFVTVTRPRAENPCCPETVCV 5487
Query: 391 CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC----DSCTYHSQVYANGQNFTDADSPCH 446
C +CPP TQ G CCP+ C+Y+ Y G F A PCH
Sbjct: 5488 CNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGA-LPCH 5546
Query: 447 ACHC-----QDGTVTCSLVDCPPTTCARP---QSGPGQCCPRCPD--CILE--EEVFVDG 494
C C QD TV C C TTC + + GQCC C C+ + V ++
Sbjct: 5547 MCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNE 5606
Query: 495 ESFSHPRDPCQECRCQ-EGHAHC---QPRPCPR-APCAHPLPGTCCPNDC 539
+ D C C+ EG H QP CP + C L T C C
Sbjct: 5607 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSC 5656
Score = 58.9 bits (141), Expect = 4e-08
Identities = 70/276 (25%), Positives = 94/276 (34%), Gaps = 61/276 (22%)
Query: 243 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSV--QCEPLPC----PPVPCRHP 296
G C C +G GE S C C C GSV QC+PLPC P PC P
Sbjct: 5409 GICVQACPCVGPDGFPKFPGERWVSN--CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRP 5466
Query: 297 G-------KIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRC--SCQAGEVS-CEEQ 346
G + CCP ET + C + C G+ S C ++
Sbjct: 5467 GFVTVTRPRAENPCCP---------------ETVCVCNTTTCPQSLPVCPPGQESICTQE 5511
Query: 347 E---CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC 403
E CP C QL C +G + G + P PC C C G + V C
Sbjct: 5512 EGDCCPTFRCR-----PQL---CSYNGTFYGVGATF-PGALPCHMCTCLSGDTQDPTVQC 5562
Query: 404 PPAPCQHPTQP--------PGACCPSC--DSC-TYHSQVYANGQNFTDA---DSPCHACH 449
C + T P G CC C +C T Q + + ++ + + C
Sbjct: 5563 QEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLCE 5622
Query: 450 CQDGT--VTCSLVDCPPTTCARPQSGPGQCCPRCPD 483
+ G +T CP + R CC C +
Sbjct: 5623 AEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEE 5658
Score = 56.6 bits (135), Expect = 2e-07
Identities = 81/306 (26%), Positives = 113/306 (36%), Gaps = 91/306 (29%)
Query: 106 GARWEPDACTACVCQDGAA--HCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLT 163
G RW + C +CVC +G+ C P LP C GQ P C +T
Sbjct: 5428 GERWVSN-CQSCVCDEGSVSVQCKP---LP----CDAQGQ---------PPPCNRPGFVT 5470
Query: 164 GA-VQCQGPSCSELNCLESCT---------PP----------GECCPI------CCTEGG 197
+ + P C E C+ + T PP G+CCP C+ G
Sbjct: 5471 VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNG 5530
Query: 198 SHWEHGQEWTTPGD-PCRICRCLEGH-----IQCRQREC-ASLCP--YPARPLPGTCCPV 248
+ + G T PG PC +C CL G +QC++ C + CP + + + G CC
Sbjct: 5531 TFYGVGA--TFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGE 5588
Query: 249 C--DGCFLNGREHRSGEPV--------GSGDPCSHCRC-ANGSVQC---EPLPCPPV-PC 293
C C G+PV D C+ C A G V +P CP V C
Sbjct: 5589 CVQTACLT-----PDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSC 5643
Query: 294 RHPGKIPGQCCPVC--DGCE---------YQGHQYQSQETFRLQERGLCVRCSCQAGEVS 342
R + G CC C D C+ +QG + + TF G C S + E
Sbjct: 5644 RGSLRKTG-CCYSCEEDSCQVRINTTILWHQGCETEVNITFC---EGSCPGASKYSAEAQ 5699
Query: 343 CEEQEC 348
+ +C
Sbjct: 5700 AMQHQC 5705
Score = 50.4 bits (119), Expect = 1e-05
Identities = 69/283 (24%), Positives = 93/283 (32%), Gaps = 50/283 (17%)
Query: 97 WGLGRAWPEGARWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPD 154
W L + P+ A D CTA + A C H P C + E D
Sbjct: 1058 WKLSPSCPD-ALAPKDPCTANPFRKSWAQKQCSI-LHGPTFAACRSQVDSTKYYEACVND 1115
Query: 155 ACTT-----CRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCT----EGGSHWEHGQE 205
AC C C AV +C + S P + CP+ C GG W +
Sbjct: 1116 ACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTP-DTCPLFCDFYNPHGGCEWHY--- 1171
Query: 206 WTTPGDPC-RICRCLEGHIQCRQ---RECASLCPYPARPLPGT----CCPVCDGCF-LNG 256
G PC + CR GH C CP P++P C C GC+ +G
Sbjct: 1172 -QPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-PSQPFFNEDQMKCVAQC-GCYDKDG 1228
Query: 257 REHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQ 316
+ G V + + C C C +QC C C Y+
Sbjct: 1229 NYYDVGARVPTAENCQSCNCTPSGIQC-----------------AHSLEACT-CTYEDRT 1270
Query: 317 YQSQETFRLQERGL--CVRCSCQA-GEVSCEEQECPVTPCALP 356
Y Q+ GL C+ C + G + + CP TP P
Sbjct: 1271 YSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTP 1313
Score = 44.3 bits (103), Expect = 0.001
Identities = 43/148 (29%), Positives = 50/148 (33%), Gaps = 30/148 (20%)
Query: 156 CTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWT-TPGDPCR 214
C TC C T + C+ E CP C H E G T T +P R
Sbjct: 294 CPTCPCATFVEYSR--QCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQR 351
Query: 215 ICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------------CFLNGREHRS 261
C E H C C P PG C V D C GR +
Sbjct: 352 AQLC-EDH-------CVDGCFCP----PGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP 399
Query: 262 GEPVGSGDPCSHCRCANGSVQCEPLPCP 289
G + CS C C+ G QC+ LPCP
Sbjct: 400 GTSFNT--TCSSCTCSGGLWQCQDLPCP 425
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/173 (26%), Positives = 58/173 (33%), Gaps = 33/173 (19%)
Query: 89 CH-----PASPQCWGL--GRAWPEGARWEPDACTACVCQD------GAAHCGPQAHLPHC 135
CH PA +C L A+ + C C C AH G Q C
Sbjct: 262 CHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRC 321
Query: 136 -----RGCSQNGQTYGNGETFS-----PDACTTCR--CLTGAVQCQGPSCSELNCL--ES 181
R C N Q G + P C C+ G G SC+ L+ +
Sbjct: 322 PELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG 381
Query: 182 CTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLC 234
C P G+C CT GG + G + T C C C G QC+ C C
Sbjct: 382 CLPLGQCP---CTHGGRTYSPGTSFNTT---CSSCTCSGGLWQCQDLPCPGTC 428
Score = 42.4 bits (98), Expect = 0.003
Identities = 38/162 (23%), Positives = 58/162 (35%), Gaps = 28/162 (17%)
Query: 304 CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLC 363
CP C + + Q C + ++ + QEC +PC S Q
Sbjct: 294 CPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECG-SPCTDTCSNPQRA 352
Query: 364 PACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD 423
CE + +G + P GR CT D + G + P G C
Sbjct: 353 QLCE---DHCVDGC-FCPPGRSCTVL---DDITHSGCL------------PLGQC----- 388
Query: 424 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPT 465
CT+ + Y+ G +F ++ C +C C G C + CP T
Sbjct: 389 PCTHGGRTYSPGTSF---NTTCSSCTCSGGLWQCQDLPCPGT 427
Score = 40.4 bits (93), Expect = 0.013
Identities = 56/226 (24%), Positives = 70/226 (30%), Gaps = 48/226 (21%)
Query: 597 QCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPC- 655
QCP P P A + +E C R L C L A A Q C
Sbjct: 243 QCPDPLPLP---AGNCTDEEGI------CHRTLLGPAFAECHALVDSTAYLAACAQDLCR 293
Query: 656 CPSCDGCLY--QGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCC 713
CP+C + ++ A P LC P CP + C
Sbjct: 294 CPTCPCATFVEYSRQCAHAGGQPRNWRCPELC---------------PRTCPLNMQHQEC 338
Query: 714 --PDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHC 771
P D C + L D C C G GC +P G C
Sbjct: 339 GSPCTDTCSNPQRAQLCEDHCVDG------CFCPPGRSCTVLDDITHSGC----LPLGQC 388
Query: 772 CPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCP 817
C + G T + G + + TCS CTC G +CQ PCP
Sbjct: 389 -----PCTHGGRTYSPGTSF----NTTCSSCTCSGGLWQCQDLPCP 425
Score = 40.4 bits (93), Expect = 0.013
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 24/194 (12%)
Query: 761 CSHPL-IPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPA 819
C PL +P+G+C +G + + + +D T L C + RC PC
Sbjct: 244 CPDPLPLPAGNCTDE-EGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATF 302
Query: 820 L-----CPHPSPGP--CFCP-VCHSCLSQGREHQD-GEEFEGPAGSCEWCRCQAGQVSCV 870
+ C H P CP +C +HQ+ G + + R Q + CV
Sbjct: 303 VEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQ--RAQLCEDHCV 360
Query: 871 R-LQCPP-LPCKL--QVTERGSCCP--RCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEG 924
CPP C + +T G C P +C C G + G+ + ++ CSSC C G
Sbjct: 361 DGCFCPPGRSCTVLDDITHSG-CLPLGQCP-CTHGGRTYSPGTSF---NTTCSSCTCSGG 415
Query: 925 VVTCARIQCISSCA 938
+ C + C +C+
Sbjct: 416 LWQCQDLPCPGTCS 429
Score = 37.0 bits (84), Expect = 0.14
Identities = 40/145 (27%), Positives = 50/145 (34%), Gaps = 14/145 (9%)
Query: 386 CTACVCQDGVPKCGAVLCPPAPCQHPT-QPPGACCPSC--DSCTYHSQVYANGQNFTDAD 442
C +C+ C + C H QP CP +C + Q G TD
Sbjct: 287 CAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 346
Query: 443 S-PCHACHCQDGTVTCSLVDCPP--TTCARPQSGPGQCCP--RCPDCILEEEVFVDGESF 497
S P A C+D V CPP + C P +CP C + G SF
Sbjct: 347 SNPQRAQLCEDHCVDGCF--CPPGRSCTVLDDITHSGCLPLGQCP-CTHGGRTYSPGTSF 403
Query: 498 SHPRDPCQECRCQEGHAHCQPRPCP 522
+ C C C G CQ PCP
Sbjct: 404 N---TTCSSCTCSGGLWQCQDLPCP 425
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/212 (25%), Positives = 66/212 (31%), Gaps = 62/212 (29%)
Query: 789 ETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCP-HP-----------SPGPCFCPVCHS 836
E PDPL CT +EG C + PA H + C CP C
Sbjct: 242 EQCPDPLPLPAGNCTDEEGI--CHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC-P 298
Query: 837 CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCP----- 891
C + F + C Q C L P +Q E GS C
Sbjct: 299 CAT----------FVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 348
Query: 892 --RCRGCLAHGEEHPEGSRWVPPDSACSSC--VCHEGVVTCARIQCISSCAQPRQGPHDC 947
R + C E+H + PP +C+ + H G + P
Sbjct: 349 PQRAQLC----EDHCVDGCFCPPGRSCTVLDDITHSGCL-----------------PLGQ 387
Query: 948 CPQCSDCEHEGRKYEPGESFQPGADPCEVCIC 979
CP C H GR Y PG SF C C C
Sbjct: 388 CP----CTHGGRTYSPGTSFN---TTCSSCTC 412
Score = 35.8 bits (81), Expect = 0.32
Identities = 50/191 (26%), Positives = 57/191 (29%), Gaps = 61/191 (31%)
Query: 437 NFTDADSPCHACHCQDGTVTC-SLVDCPPTTCARPQSGPGQC-CPRCPDCILEEEVFVDG 494
N TD + CH C +LVD A Q C CP CP E
Sbjct: 254 NCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQD---LCRCPTCPCATFVEYSRQCA 310
Query: 495 ESFSHPRDPCQECRCQEGHAHCQPRPCP----RAPCAHPLPGTC--------CPNDC--- 539
+ PR+ RC E PR CP C P TC C + C
Sbjct: 311 HAGGQPRN----WRCPE----LCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDG 362
Query: 540 -----------------SGC--------AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQC 574
SGC GG+ Y G F + C C C G Q
Sbjct: 363 CFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF---NTTCSSCTCSGGLWQ- 418
Query: 575 LARRCVPLPCP 585
C LPCP
Sbjct: 419 ----CQDLPCP 425
Score = 35.0 bits (79), Expect = 0.55
Identities = 49/219 (22%), Positives = 69/219 (31%), Gaps = 56/219 (25%)
Query: 797 PTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE-------- 848
PT + C Q S + + C C S G C C C + + + D
Sbjct: 1094 PTFAACRSQVDSTKYYEA-CVNDACACDSGGDCEC-FCTAVAAYAQACHDAGLCVSWRTP 1151
Query: 849 -------EFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRC-------- 893
+F P G CEW G + P C + + C P+C
Sbjct: 1152 DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFN 1211
Query: 894 ---RGCLAH-------GEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQG 943
C+A G + G+R VP C SC C T + IQC S
Sbjct: 1212 EDQMKCVAQCGCYDKDGNYYDVGAR-VPTAENCQSCNC-----TPSGIQCAHSL------ 1259
Query: 944 PHDCCPQCSDCEHEGRKYEPGE---SFQPGADPCEVCIC 979
+ C +E R Y + + G C + IC
Sbjct: 1260 ------EACTCTYEDRTYSYQDVIYNTTDGLGACLIAIC 1292
Score = 32.3 bits (72), Expect = 3.5
Identities = 45/189 (23%), Positives = 53/189 (28%), Gaps = 67/189 (35%)
Query: 117 CVCQDG-----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP 171
C C G A C P P C +G GE D C C G + C G
Sbjct: 735 CTCPAGTFLNDAGACVPAQECP----CYAHGTVLAPGEVVH-DEGAVCSCTGGKLSCLGA 789
Query: 172 SCSE----------LNCLESC--TPPGECCPICCT------------------------E 195
S + L+C S TP EC C T
Sbjct: 790 SLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGS 849
Query: 196 GGSHWE------HGQEWTTPGDP----CRICRCLEGHIQCRQRECASLCPYPARPLPGTC 245
GG E H + PG+ C C C +C R C GTC
Sbjct: 850 GGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCL-----------GTC 898
Query: 246 CPVCDGCFL 254
DG F+
Sbjct: 899 VAYGDGHFI 907
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 164 bits (416), Expect = 5e-40
Identities = 143/511 (27%), Positives = 194/511 (37%), Gaps = 89/511 (17%)
Query: 1017 PTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQAC-PELSCPLSERHTPPGSC 1075
P ++ S SE G+ AP TCQ C+ C P C G C
Sbjct: 767 PKTFKSCSQSSENKFGAACAP-----TCQMLATGVACVPTKCEPGCVCAEGLYENADGQC 821
Query: 1076 CPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALS 1135
P P C G G D C +CSC G CQ
Sbjct: 822 VPPEECP---CEFSGVSYPGGAELHTD-CRTCSCSRGRWACQQ----------------- 860
Query: 1136 PGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKD-CHSGD----FSVHVT 1190
G+ CP ++C +G+ H TFDG+ F G+C Y+LA D C D F +
Sbjct: 861 -GTHCP------STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTE 913
Query: 1191 NDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVIL 1250
N G SGV ++ + + LG ++V +L D TV G +EP + + + + L
Sbjct: 914 NVICGNSGVTCSRAIKIFLGGLSV-VLADRNYTVTG--------EEPHVQLGVTPGALSL 964
Query: 1251 HAQ---PG---LQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSE 1304
PG L ++W+ + + + + Q CGLCGNFNG +DD + + SE
Sbjct: 965 VVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSE 1024
Query: 1305 AAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPP 1364
NSW+ S DPC +R R A +C V+ S F+ CH+ V
Sbjct: 1025 LELVNSWKESPLCG-----DVSFVTDPCSLNAFR-RSWAERKCSVINSQTFATCHSKVYH 1078
Query: 1365 EPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
P++ ACV D C C G + CLCDA+ AYA C GV WR P C + C
Sbjct: 1079 LPYYEACVRDACGCDSGGDCE-CLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTH 1137
Query: 1425 VFDECG--------------PPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEA 1470
D G PC Q +P G C C E
Sbjct: 1138 TQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVP-GSNIEGCY-----NCSQDEYFDHEEG 1191
Query: 1471 HCIP--------PEACPQVLLTGDQPLGARP 1493
C+P P PQ+ TG +P P
Sbjct: 1192 VCVPCMPPTTPQPPTTPQLPTTGSRPTQVWP 1222
Score = 142 bits (359), Expect = 2e-33
Identities = 145/547 (26%), Positives = 207/547 (37%), Gaps = 97/547 (17%)
Query: 966 SFQPGADPCEVCICEPQPEGPPSLRC-----HRRQCPSLVGCPPSQLLPPGP-------- 1012
S +P C+ + GP + C + RQC S+VG P + PG
Sbjct: 246 SKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC-SMVGQPVRRWRSPGLCSVGQCPA 304
Query: 1013 ----QHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSC--PLS 1066
Q C C + SN P ++C T+ C CPE + LS
Sbjct: 305 NQVYQECGSACVKTCSN--------------PQHSCS-SSCTFGCF---CPEGTVLNDLS 346
Query: 1067 ERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSC 1126
HT C PV + P CV G A GE T+ C +C C G C + C
Sbjct: 347 NNHT----CVPVTQCP---CVLHGAMYAPGEV-TIAACQTCRCTLGRWVCTERPC----- 393
Query: 1127 GPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFS 1186
P C G TFD R F G+C+Y+L + +
Sbjct: 394 --------------------PGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDG 433
Query: 1187 VHVTNDDRGRSGVAWTQEVAVLLGDMAVRLL--QDGAVTVDGHPVALPFLQEPLLYVELR 1244
+ D+ + T VAV+ +++ QD VT +G LP+ +
Sbjct: 434 ALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQT 493
Query: 1245 GHTVILHAQPGLQVLWDGQS--QVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLP 1302
+ + GL+++ + Q V+V ++G+T GLCGNFNG DD G+
Sbjct: 494 STHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEG 553
Query: 1303 SEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVL--KSSPFSRCHA 1360
+ + F +SW+ P + RE DPC + + A C +L + F RCHA
Sbjct: 554 TASLFVDSWRAG-----NCPAALERETDPCSMSQLN-KVCAETHCSMLLRTGTVFERCHA 607
Query: 1361 VVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTP-TWRGPT-LCVVGC 1418
V P PF+ CVY C +C AL Y C GV WR C + C
Sbjct: 608 TVNPAPFYKRCVYQACNY---EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPC 664
Query: 1419 PLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP--GCQCPAG-LVEHEAHCIPP 1475
F ++ C RTC + L + A C VP GC CP G + + C+
Sbjct: 665 TGNTTFSYN--SQACERTC----LSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRK 718
Query: 1476 EACPQVL 1482
CP +L
Sbjct: 719 AQCPCIL 725
Score = 124 bits (312), Expect = 5e-28
Identities = 116/402 (28%), Positives = 161/402 (40%), Gaps = 59/402 (14%)
Query: 1097 ERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDP 1156
+RW + +C AG +P L P+ P C +G
Sbjct: 3 QRWLLLSCCGALLSAGLANTSYT-----------SPGLQRLKDSPQTAPDKGQCSTWGAG 51
Query: 1157 HYRTFDGRLLHFQGSCSYVLAKDCHSG--DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAV 1214
H+ TFD + F G+C+Y+ A C FSV + RG G + V LG V
Sbjct: 52 HFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLR---RGPDGSI--SRIIVELGASVV 106
Query: 1215 RLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQP---GLQVLWDGQSQVEVSVP 1271
+ + D ++LP+ L G +V L A+ L+V+W S + V V
Sbjct: 107 TVSEAIISVKDIGVISLPYTSNGLQITPF-GQSVRLVAKQLELELEVVWGPDSHLMVLVE 165
Query: 1272 GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDP 1331
Y G+ CGLCGNF+G ++ EG L F ++ + PG C+
Sbjct: 166 RKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPH-KFAALQKLDD---PGEICTFQ----- 216
Query: 1332 CRAAGYRARREANAR-CGVLKSSPFSRCHAVVPPEPFFAACVYDLCAC---GPGSSADAC 1387
R+ +AR C L + C V EPF +C D+ A GP +S+
Sbjct: 217 -DIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNSS--- 270
Query: 1388 LCDALEAYASHCRQAG-VTPTWRGPTLCVVG-CPLERGFVFDECGPPCPRTCFN-QHIPL 1444
C L Y+ C G WR P LC VG CP + V+ ECG C +TC N QH
Sbjct: 271 -CATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQ--VYQECGSACVKTCSNPQH--- 324
Query: 1445 GELAAHCVRPCVPGCQCPAGLVEHEAH----CIPPEACPQVL 1482
C C GC CP G V ++ C+P CP VL
Sbjct: 325 -----SCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVL 361
Score = 45.8 bits (107), Expect = 3e-04
Identities = 52/202 (25%), Positives = 62/202 (30%), Gaps = 49/202 (24%)
Query: 408 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH------------------ACH 449
C H P C +C TY +Q G+ A PC CH
Sbjct: 691 CHHSAVPVDGC--NCPDGTYLNQ---KGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
Query: 450 CQDGTVTCSLVDCPPTTCARPQSGPGQC-CPRC-PDCILEEEVFVDGESFSHPRDPCQEC 507
C +G ++C RPQ C P+ C E F P C
Sbjct: 746 CINGRLSCP---------QRPQMFLASCQAPKTFKSCSQSSE-----NKFGAACAPT--C 789
Query: 508 RCQEGHAHCQPRPC-PRAPCAHPL----PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPC 562
+ C P C P CA L G C P + C F G YP GA+ C
Sbjct: 790 QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAEL---HTDC 846
Query: 563 RLCRCLSGNVQCLARRCVPLPC 584
R C C G C P C
Sbjct: 847 RTCSCSRGRWACQQGTHCPSTC 868
Score = 45.1 bits (105), Expect = 5e-04
Identities = 58/224 (25%), Positives = 73/224 (32%), Gaps = 41/224 (18%)
Query: 161 CLTGAVQCQGPSCSELNCLESCTPPGEC-----CPICCTEGGSHWEHGQEWTTPGDPCRI 215
C AV G +C + L GEC CP C EG Q G C
Sbjct: 691 CHHSAVPVDGCNCPDGTYLNQ---KGECVRKAQCP-CILEGYKFILAEQSTVINGITCH- 745
Query: 216 CRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-C 274
C+ G + C QR L A +C + F G C+ C
Sbjct: 746 --CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF--------------GAACAPTC 789
Query: 275 RCANGSVQCEPLPCPPVPCRHPG---KIPGQCCPVCD-GCEYQGHQYQSQETFRLQERGL 330
+ V C P C P G GQC P + CE+ G Y
Sbjct: 790 QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTD---- 845
Query: 331 CVRCSCQAGEVSCEE-QECPVTPCALPASGRQLCPACELDGEEF 373
C CSC G +C++ CP T C L G + DG+ F
Sbjct: 846 CRTCSCSRGRWACQQGTHCPST-CTLYGEGHVI----TFDGQRF 884
Score = 44.3 bits (103), Expect = 0.001
Identities = 59/222 (26%), Positives = 77/222 (34%), Gaps = 41/222 (18%)
Query: 618 FSPPGDPCRR-CLCL-DGSVSCQRLPCPPAPCAHP------RQGPC-----CPSCDGCLY 664
FS C R CL L D + C P C P ++G C CP C+
Sbjct: 670 FSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCP----CIL 725
Query: 665 QGKEFASGERFPSPTAACHLCLCWEGSVSCEPKA-CAPALCPFPARGDCCPDCDGCEYLG 723
+G +F E+ S C C G +SC + A C P C
Sbjct: 726 EGYKFILAEQ--STVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSC---------- 773
Query: 724 ESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPG-CSHPLIPS--GHCCPTCQ-GCR 779
S S +F P C L V C CEP C+ L + G C P + C
Sbjct: 774 -SQSSENKFGAACAPT--CQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCE 830
Query: 780 YHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821
+ GV+ G L C C+C G CQ+ P+ C
Sbjct: 831 FSGVSYPGGAEL----HTDCRTCSCSRGRWACQQGTHCPSTC 868
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/250 (25%), Positives = 87/250 (34%), Gaps = 47/250 (18%)
Query: 298 KIPGQCCPVCDGCEYQ-GHQYQSQE-TFRLQERGLCVRCSCQAGEVSCEEQECPVTPCAL 355
K GQ C +C + + +++ S+E F + ++ GE+ C Q+ P T
Sbjct: 167 KYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEI-CTFQDIPSTHVRQ 225
Query: 356 PASGR-------QLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPK--CGAVLCPPA 406
R + P C + E F Q + P Q G C +
Sbjct: 226 AQHARICTQLLTLVAPECSVSKEPFVLSCQADVAAAP------QPGPQNSSCATLSEYSR 279
Query: 407 PCQHPTQP------PGAC----CPSCDSCTYHSQVY--ANGQNFTDADSPCHACHCQDGT 454
C QP PG C CP+ +QVY +P H+C T
Sbjct: 280 QCSMVGQPVRRWRSPGLCSVGQCPA-------NQVYQECGSACVKTCSNPQHSCS-SSCT 331
Query: 455 VTCSLVDCPPTTCARPQSGPGQCCP--RCPDCILEEEVFVDGESFSHPRDPCQECRCQEG 512
C CP T S C P +CP C+L ++ GE CQ CRC G
Sbjct: 332 FGCF---CPEGTVLNDLSNNHTCVPVTQCP-CVLHGAMYAPGEVTIAA---CQTCRCTLG 384
Query: 513 HAHCQPRPCP 522
C RPCP
Sbjct: 385 RWVCTERPCP 394
Score = 41.6 bits (96), Expect = 0.006
Identities = 41/159 (25%), Positives = 54/159 (33%), Gaps = 44/159 (27%)
Query: 134 HCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICC 193
+ R CS GQ SP C+ +C V + S C+++C+ P C C
Sbjct: 277 YSRQCSMVGQPVRRWR--SPGLCSVGQCPANQVYQECGSA----CVKTCSNPQHSCSSSC 330
Query: 194 TEGGSHWEHGQEWTTPGDPCRICRCLEGHIQ---CRQRECASLCPYPARPLPGTCCPVCD 250
T G C C EG + C +P T CP
Sbjct: 331 TFG-------------------CFCPEGTVLNDLSNNHTC----------VPVTQCP--- 358
Query: 251 GCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
C L+G + GE + C CRC G C PCP
Sbjct: 359 -CVLHGAMYAPGEVTIAA--CQTCRCTLGRWVCTERPCP 394
Score = 40.4 bits (93), Expect = 0.013
Identities = 44/185 (23%), Positives = 61/185 (32%), Gaps = 59/185 (31%)
Query: 742 CTCLGGFVTCGRRP------CEPPGCSHPLIPSGH------CCPTCQGCRYHGVTTASGE 789
C C+ G ++C +RP C+ P S C PTCQ +
Sbjct: 744 CHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQ------MLATGVA 797
Query: 790 TLPDPLDPTCSLCTCQEGSMRCQKKPC-PPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
+P +P C C EG C PP CP C G + G
Sbjct: 798 CVPTKCEPGC---VCAEGLYENADGQCVPPEECP--------------CEFSGVSYPGGA 840
Query: 849 EFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHP---E 905
E C C C G+ +C ++G+ CP C +GE H +
Sbjct: 841 ELHT---DCRTCSCSRGRWAC---------------QQGTHCPST--CTLYGEGHVITFD 880
Query: 906 GSRWV 910
G R+V
Sbjct: 881 GQRFV 885
Score = 35.4 bits (80), Expect = 0.42
Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 15/88 (17%)
Query: 106 GARWEPDACT-ACVCQDGA-----AHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTC 159
G P C CVC +G C P P C +G +Y G D C TC
Sbjct: 795 GVACVPTKCEPGCVCAEGLYENADGQCVPPEECP----CEFSGVSYPGGAELHTD-CRTC 849
Query: 160 RCLTGAVQCQGPSCSELNCLESCTPPGE 187
C G CQ +C +CT GE
Sbjct: 850 SCSRGRWACQ----QGTHCPSTCTLYGE 873
Score = 34.3 bits (77), Expect = 0.93
Identities = 32/125 (25%), Positives = 42/125 (33%), Gaps = 12/125 (9%)
Query: 595 CPQCPAP--AGCPRPGAAHARHQEYFSPPGDPCR-RCLCLDGSVSCQRLPCPPA-PCAHP 650
CPQ P A C P + Q + G C C L V+C C P CA
Sbjct: 753 CPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEG 812
Query: 651 ----RQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCP 705
G C P + C + G + G + C C C G +C+ P+ C
Sbjct: 813 LYENADGQCVPPEECPCEFSGVSYPGGAELHTD---CRTCSCSRGRWACQQGTHCPSTCT 869
Query: 706 FPARG 710
G
Sbjct: 870 LYGEG 874
Score = 33.5 bits (75), Expect = 1.6
Identities = 48/191 (25%), Positives = 63/191 (32%), Gaps = 53/191 (27%)
Query: 802 CTCQEGSMRCQKKPCP-PALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWC 860
C C +G+ QK C A CP C+ +G + E+ G C
Sbjct: 701 CNCPDGTYLNQKGECVRKAQCP--------------CILEGYKFILAEQSTVINGIT--C 744
Query: 861 RCQAGQVSCV-RLQCPPLPCKLQVTERG-----------SCCPRCRGCLAHGEEHPEGSR 908
C G++SC R Q C+ T + +C P C+ LA G
Sbjct: 745 HCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQ-MLATGVA------ 797
Query: 909 WVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQ 968
P CVC EG+ A QC+ P + CP CE G Y G
Sbjct: 798 -CVPTKCEPGCVCAEGLYENADGQCV---------PPEECP----CEFSGVSYPGGAELH 843
Query: 969 PGADPCEVCIC 979
C C C
Sbjct: 844 ---TDCRTCSC 851
Score = 32.3 bits (72), Expect = 3.5
Identities = 23/85 (27%), Positives = 30/85 (35%), Gaps = 12/85 (14%)
Query: 734 DPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ-GCRYHGVTTASGETLP 792
+P+ C+ G F C + L + C P Q C HG A GE
Sbjct: 321 NPQHSCSSSCTFGCF-------CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI 373
Query: 793 DPLDPTCSLCTCQEGSMRCQKKPCP 817
C C C G C ++PCP
Sbjct: 374 ----AACQTCRCTLGRWVCTERPCP 394
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 160 bits (406), Expect = 7e-39
Identities = 133/430 (30%), Positives = 182/430 (42%), Gaps = 50/430 (11%)
Query: 1083 TQSCVHQGREVASGERWTV-----DTCTSCSCMAGTVRCQSQRCSP---LSCGPDKAPAL 1134
+ S HQ +A G++ TV + S + + R +C+P SC + +
Sbjct: 62 SSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCF-NGGECV 120
Query: 1135 SPGSC-C-------PRCL-------PRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA-- 1177
P C C PRC R + C A+G H TFDG + G SY L
Sbjct: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180
Query: 1178 KDCHSGDFSVHVTNDDR-GRSGVAWTQEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQ 1235
+ FS+ V ND + G S ++ V++ +G+ + L ++ VT G V LP +
Sbjct: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVM 238
Query: 1236 EPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQG 1295
+L G+ ++ H Q + WDG S V + + G T GLCGN N +DDL
Sbjct: 239 GSARLQQLAGYVIVRH-QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVT 297
Query: 1296 PEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPF 1355
G L F +SWQ P P ++ PC + +C L PF
Sbjct: 298 SSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPF 357
Query: 1356 SRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-T 1412
CHA V P PF A+C DLC S D A C AL YA C QAG WR
Sbjct: 358 DACHAYVSPLPFTASCTSDLCQ----SMGDVATWCRALAEYARACAQAGRPLQGWRTQLR 413
Query: 1413 LCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR---PCVPGCQCPAGLVEHE 1469
C V C E+ F ++EC CP +C + A CV CV GC CP GL+ +
Sbjct: 414 QCTVHCK-EKAFTYNECIACCPASCHPR--------ASCVDSEIACVDGCYCPNGLIFED 464
Query: 1470 AHCIPPEACP 1479
C+ P CP
Sbjct: 465 GGCVAPAECP 474
Score = 160 bits (405), Expect = 9e-39
Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)
Query: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902
F P E CR C+ GQ C L C+ L V R R C E
Sbjct: 726 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 781
Query: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949
E S V P D A +G +R +C+ CA P D C P
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
QCS C +G Y PG+S P C C+ +G S C R
Sbjct: 842 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 877
Query: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
P CP + NCS+ EL+ C Q L L + P LS
Sbjct: 878 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 924
Query: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120
G CP C P + C +G+E G++ + C +C C G+ +C
Sbjct: 925 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 980
Query: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180
C+ ++C A+GD HYRTFDG F G+C L K
Sbjct: 981 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015
Query: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240
FSV V N + SG+ + +++ +G+ + D G+P FL +
Sbjct: 1016 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 1070
Query: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE
Sbjct: 1071 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1130
Query: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356
L L + FG+SW E +DP RE A C +L S F
Sbjct: 1131 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1181
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416
CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC
Sbjct: 1182 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1240
Query: 1417 GC 1418
C
Sbjct: 1241 DC 1242
Score = 159 bits (403), Expect = 1e-38
Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)
Query: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102
C +C P SC SE G CP C AP + C G G D
Sbjct: 432 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 491
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
C +C+C +G C + C PA C GD H+ TFD
Sbjct: 492 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 525
Query: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218
GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q
Sbjct: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 585
Query: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276
G V + D + + P+ + L + + G++VL+D + ++ + V +
Sbjct: 586 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332
T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 702
Query: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
+AA Y + C VL F+ C A + P P+F C D C CG CLC L
Sbjct: 703 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 752
Query: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445
YA CR+ G+ +R C + C E + C PC RTC + P
Sbjct: 753 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 810
Query: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496
+L+ CV GC CP L C+P C D P G PS
Sbjct: 811 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861
Score = 84.3 bits (207), Expect = 8e-16
Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)
Query: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154
C C+ G +R QSQ C +P CG A + CCP C R C F
Sbjct: 2059 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2115
Query: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211
D + TFDG + Y+L++ +VHV + G + W V+L
Sbjct: 2116 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2174
Query: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265
+A ++ D VTVD PV P + +E GH ++ +Q+ W G
Sbjct: 2175 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2233
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322
VE S QG GLCG +G A +DL +G ++ A F +SWQV L
Sbjct: 2234 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2286
Query: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379
S G+ D C A + + ++ + FS CH VPPE F + D
Sbjct: 2287 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2335
Query: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437
+ C AL Y + C + V WR C C + + C C P+TC
Sbjct: 2336 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2391
Query: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
Q LG L + GC C G + H H CIP C
Sbjct: 2392 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433
Score = 58.5 bits (140), Expect = 5e-08
Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)
Query: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
C C D E VDG D C EG A CP C P
Sbjct: 792 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 839
Query: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
+ C F G +YP G +D P C C G + C +R P C
Sbjct: 840 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 883
Query: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651
P C H + C + L L+ SVS R PC CA P R
Sbjct: 884 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 934
Query: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700
G C P C ++GKE+ G++ SP CH C+C GS C CA
Sbjct: 935 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 982
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
PC P G C +P C G GD R C++G C
Sbjct: 787 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 824
Query: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
PP + C P C +QG ++ G+ CH C +G +SC+ +A A
Sbjct: 825 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 881
Query: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758
A CP G+ +++ + E TC L R PC
Sbjct: 882 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924
Query: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814
GC+ P L+ G C P C + G G+ + P C C CQ GS +C
Sbjct: 925 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 979
Query: 815 PC 816
PC
Sbjct: 980 PC 981
Score = 50.8 bits (120), Expect = 1e-05
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372
C A +E PC A R ++ + CGV SR V PP+ + CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
+ C+C PG S D HC+ ++ R P CP G
Sbjct: 839 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 887
Query: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
VF C RTC Q L L+ PC+ GC CP GL+ H C PE
Sbjct: 888 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 944
Query: 1478 CP 1479
CP
Sbjct: 945 CP 946
Score = 50.8 bits (120), Expect = 1e-05
Identities = 52/185 (28%), Positives = 64/185 (34%), Gaps = 54/185 (29%)
Query: 771 CCPTCQ-GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPC 829
C P Q C + GV G D P+ C C++G M C + P A CP G
Sbjct: 837 CVPRNQCSCHFQGVDYPPG----DSDIPSLGHCHCKDGVMSCDSR-APAAACP---AGQV 888
Query: 830 F--CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERG 887
F C H+ L RE C L V+ RG
Sbjct: 889 FVNCSDLHTDLELSRERT----------------------------CEQQLLNLSVSARG 920
Query: 888 SCCPRC---RGCLAHG------EEHP---EGSRWVPPD---SACSSCVCHEGVVTCARIQ 932
C C +G L HG EE P +G + P D S C +CVC G C
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 980
Query: 933 CISSC 937
C S+C
Sbjct: 981 CASTC 985
Score = 50.4 bits (119), Expect = 1e-05
Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)
Query: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304
SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C
Sbjct: 691 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 747
Query: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
+C + H ++ FR + + C E S E C V PC
Sbjct: 748 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 800
Query: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396
AC +DG +E EG PD P C C +P
Sbjct: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860
Query: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454
G C ++ P A CP+ QV+ N + TD + S C Q
Sbjct: 861 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 913
Query: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
++ S + CA PQ G C CP +E F + S PC C C
Sbjct: 914 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 969
Query: 510 QEGHAHCQPRPC 521
Q G C PC
Sbjct: 970 QRGSFQCTLHPC 981
Score = 48.1 bits (113), Expect = 6e-05
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321
V GD S C G CPP + + +P C C +QG Y +
Sbjct: 807 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 856
Query: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375
+ + G C C+ G +SC+ + CP + S L EL E E
Sbjct: 857 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 910
Query: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
+ G + C C G+ + G P C CT+ + Y
Sbjct: 911 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 955
Query: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
G SPCH C CQ G+ C+L C T A
Sbjct: 956 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 987
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170
C C+DG C +A C GQ + N D TC + L +V +G
Sbjct: 865 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920
Query: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
P S C + G+ C + C CT G + G + +P C C C G QC
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 977
Query: 227 QRECASLC 234
CAS C
Sbjct: 978 LHPCASTC 985
Score = 44.7 bits (104), Expect = 7e-04
Identities = 93/393 (23%), Positives = 119/393 (30%), Gaps = 124/393 (31%)
Query: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
PLDP C + C C EG++ ++ ALC + C S G GE
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2447
Query: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ C +CQA + V L CP PR CL GE +
Sbjct: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2489
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPH--------DCCPQCSDCEHEGR 959
+P C C V C + C R G CCP S
Sbjct: 2490 LLLPTKDPC----CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS------- 2538
Query: 960 KYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCP 1017
C C+P C PS C Q+L G CC
Sbjct: 2539 -----------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCT 2571
Query: 1018 TCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCP 1077
+ A +C + + +CQ+ L +H+ EL CPL + C
Sbjct: 2572 SYFCACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCE 2612
Query: 1078 VCRAPTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS------ 1125
R P C G A E W+ D C SC C T+ RC S L
Sbjct: 2613 NFRCPQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHS 2669
Query: 1126 ----CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
CG K + P CL R M G
Sbjct: 2670 VENVCGCAKYECVK----APVCLSRELGVMQPG 2698
Score = 42.0 bits (97), Expect = 0.004
Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)
Query: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586
P +C DCS C + + + F P C L + VQ C+A C +
Sbjct: 2296 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2355
Query: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628
P L + C C P C + G E+ G+ C
Sbjct: 2356 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2411
Query: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683
+C +G++ +R L P A CA C S G A GE + S + C H
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2459
Query: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732
C + G S P++C P + CC LG + NQ
Sbjct: 2460 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2511
Query: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773
P R L T C CE P C L+PS CC
Sbjct: 2512 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2571
Query: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816
+ C C GE L + T C L C + RC + C
Sbjct: 2572 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2631
Query: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
P CP+ S C C P CH + + E G C
Sbjct: 2632 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2677
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925
+ +C P C R G + G+ E S D C + C +
Sbjct: 2678 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2724
Query: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976
+ + C C Q + P D C C + + F PGA
Sbjct: 2725 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2784
Query: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024
C C P G +R S + CPP + P + CC TC E
Sbjct: 2785 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2837
Query: 1025 NCSE 1028
+C +
Sbjct: 2838 SCKK 2841
Score = 39.3 bits (90), Expect = 0.029
Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)
Query: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990
++S Q R P C CS C R + F P CE+ I + + P +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2345
Query: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033
CH+ CP L + C T E C +G+LG
Sbjct: 2346 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2397
Query: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
P DP + CQ L C+ C E + L RH+ C P + + R
Sbjct: 2398 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2443
Query: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
A GE W S ++G + Q Q PD + G CP PRP SC+ F
Sbjct: 2444 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2485
Query: 1154 GD 1155
G+
Sbjct: 2486 GE 2487
Score = 37.7 bits (86), Expect = 0.084
Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)
Query: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172
AC C C AH H C ++G + P +C C P +
Sbjct: 740 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 795
Query: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215
C +L E+C G EC C ++ + + P + C
Sbjct: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 855
Query: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235
C C +G + C R A+ CP
Sbjct: 856 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 915
Query: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280
AR L G CP D CFL G+E+ G+ V S PC C C GS
Sbjct: 916 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 973
Query: 281 VQCEPLPC 288
QC PC
Sbjct: 974 FQCTLHPC 981
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725
K F E A+CH C + ++C P F G P CE+ G
Sbjct: 422 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 481
Query: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762
Y +E CN CTC G C C P CS
Sbjct: 482 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 514
Score = 36.6 bits (83), Expect = 0.19
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173
+ C C G G LP C+ G+ Y G + SP C TC C G+ QC C
Sbjct: 924 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 981
Query: 174 SELNCLESCTPPGE 187
+ +CT G+
Sbjct: 982 A-----STCTAYGD 990
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)
Query: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338
LP PP ++PG + G QC P D C H Y S F C CQ+
Sbjct: 329 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 380
Query: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386
G+V+ C CA P G RQ C+ + E + P P
Sbjct: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 440
Query: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441
+CV C DG ++ C P + CP C +H +Y G +
Sbjct: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 490
Query: 442 DSPCHACHCQDGTVTCSLVDCP 463
C+ C C G CS CP
Sbjct: 491 --DCNTCTCTSGKWECSTAVCP 510
Score = 35.4 bits (80), Expect = 0.42
Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)
Query: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233
C+ +C PP C + G + C++ C C EG I R+ ++L
Sbjct: 2381 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2426
Query: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289
C +P C D G GE S C H A ++ L CP
Sbjct: 2427 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477
Query: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334
P C G++ CC VC+ +G + RL QE C
Sbjct: 2478 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2537
Query: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394
SC+ CE + L P+C D Q GR +C
Sbjct: 2538 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2569
Query: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
C + C C P P C ++ T H +N T+ P + C C++
Sbjct: 2570 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2613
Query: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503
C V C T P +CCP C P C L E+ +D E F H
Sbjct: 2614 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2668
Query: 504 CQECRCQEGHAHCQPRPCPRAP 525
E C C +AP
Sbjct: 2669 -----SVENVCGCAKYECVKAP 2685
Score = 33.5 bits (75), Expect = 1.6
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)
Query: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
+CT+ +CQ D A C +A + R C+Q G+ T CT V C+
Sbjct: 372 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 420
Query: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
+ + C+ CCP C S C++ I C
Sbjct: 421 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 452
Query: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
CP G C P C +G + G V + C+ C C +G +C C
Sbjct: 453 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 509
Query: 289 P 289
P
Sbjct: 510 P 510
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801
C C G + E GC P CP C +HG G + + C+
Sbjct: 454 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 494
Query: 802 CTCQEGSMRCQKKPCP 817
CTC G C CP
Sbjct: 495 CTCTSGKWECSTAVCP 510
Score = 33.1 bits (74), Expect = 2.1
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)
Query: 1426 FDECGPPCPRTCFNQHIPLGELAAHCV-----RPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
+D C PC +TC + AA C R CVP C P L E C+ E C +
Sbjct: 1412 YDACASPCFQTCRDPR------AASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVE 1465
Query: 1481 -VLLTGDQPLGARPSPSREPQETP 1503
+ + LG P + TP
Sbjct: 1466 PAVWVPTEALGNETLPPSQGLPTP 1489
Score = 32.7 bits (73), Expect = 2.7
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)
Query: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442
CT+ +CQ D C A+ C +P CT H + A N A
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495
P +CH C D + C VD CP + G CP C ++ G
Sbjct: 433 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 485
Query: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
S ++ C C C G C CP A C+
Sbjct: 486 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 514
Score = 32.7 bits (73), Expect = 2.7
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622
+C+A C P C P + E C C P GC P PPG
Sbjct: 428 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 485
Query: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648
+ C C C G C C PA C+
Sbjct: 486 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 514
Score = 32.0 bits (71), Expect = 4.6
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906
PA C +++CV CP + E G C CP C HG +P G
Sbjct: 434 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 485
Query: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938
S V D C++C C G C+ C + C+
Sbjct: 486 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 514
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 160 bits (406), Expect = 7e-39
Identities = 133/430 (30%), Positives = 182/430 (42%), Gaps = 50/430 (11%)
Query: 1083 TQSCVHQGREVASGERWTV-----DTCTSCSCMAGTVRCQSQRCSP---LSCGPDKAPAL 1134
+ S HQ +A G++ TV + S + + R +C+P SC + +
Sbjct: 62 SSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCF-NGGECV 120
Query: 1135 SPGSC-C-------PRCL-------PRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA-- 1177
P C C PRC R + C A+G H TFDG + G SY L
Sbjct: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180
Query: 1178 KDCHSGDFSVHVTNDDR-GRSGVAWTQEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQ 1235
+ FS+ V ND + G S ++ V++ +G+ + L ++ VT G V LP +
Sbjct: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVM 238
Query: 1236 EPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQG 1295
+L G+ ++ H Q + WDG S V + + G T GLCGN N +DDL
Sbjct: 239 GSARLQQLAGYVIVRH-QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVT 297
Query: 1296 PEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPF 1355
G L F +SWQ P P ++ PC + +C L PF
Sbjct: 298 SSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPF 357
Query: 1356 SRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-T 1412
CHA V P PF A+C DLC S D A C AL YA C QAG WR
Sbjct: 358 DACHAYVSPLPFTASCTSDLCQ----SMGDVATWCRALAEYARACAQAGRPLQGWRTQLR 413
Query: 1413 LCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR---PCVPGCQCPAGLVEHE 1469
C V C E+ F ++EC CP +C + A CV CV GC CP GL+ +
Sbjct: 414 QCTVHCK-EKAFTYNECIACCPASCHPR--------ASCVDSEIACVDGCYCPNGLIFED 464
Query: 1470 AHCIPPEACP 1479
C+ P CP
Sbjct: 465 GGCVAPAECP 474
Score = 160 bits (405), Expect = 9e-39
Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)
Query: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902
F P E CR C+ GQ C L C+ L V R R C E
Sbjct: 726 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 781
Query: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949
E S V P D A +G +R +C+ CA P D C P
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
QCS C +G Y PG+S P C C+ +G S C R
Sbjct: 842 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 877
Query: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
P CP + NCS+ EL+ C Q L L + P LS
Sbjct: 878 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 924
Query: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120
G CP C P + C +G+E G++ + C +C C G+ +C
Sbjct: 925 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 980
Query: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180
C+ ++C A+GD HYRTFDG F G+C L K
Sbjct: 981 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015
Query: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240
FSV V N + SG+ + +++ +G+ + D G+P FL +
Sbjct: 1016 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 1070
Query: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE
Sbjct: 1071 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1130
Query: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356
L L + FG+SW E +DP RE A C +L S F
Sbjct: 1131 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1181
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416
CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC
Sbjct: 1182 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1240
Query: 1417 GC 1418
C
Sbjct: 1241 DC 1242
Score = 159 bits (403), Expect = 1e-38
Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)
Query: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102
C +C P SC SE G CP C AP + C G G D
Sbjct: 432 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 491
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
C +C+C +G C + C PA C GD H+ TFD
Sbjct: 492 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 525
Query: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218
GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q
Sbjct: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 585
Query: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276
G V + D + + P+ + L + + G++VL+D + ++ + V +
Sbjct: 586 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332
T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 702
Query: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
+AA Y + C VL F+ C A + P P+F C D C CG CLC L
Sbjct: 703 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 752
Query: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445
YA CR+ G+ +R C + C E + C PC RTC + P
Sbjct: 753 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 810
Query: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496
+L+ CV GC CP L C+P C D P G PS
Sbjct: 811 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861
Score = 84.3 bits (207), Expect = 8e-16
Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)
Query: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154
C C+ G +R QSQ C +P CG A + CCP C R C F
Sbjct: 2059 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2115
Query: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211
D + TFDG + Y+L++ +VHV + G + W V+L
Sbjct: 2116 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2174
Query: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265
+A ++ D VTVD PV P + +E GH ++ +Q+ W G
Sbjct: 2175 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2233
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322
VE S QG GLCG +G A +DL +G ++ A F +SWQV L
Sbjct: 2234 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2286
Query: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379
S G+ D C A + + ++ + FS CH VPPE F + D
Sbjct: 2287 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2335
Query: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437
+ C AL Y + C + V WR C C + + C C P+TC
Sbjct: 2336 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2391
Query: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
Q LG L + GC C G + H H CIP C
Sbjct: 2392 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433
Score = 58.5 bits (140), Expect = 5e-08
Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)
Query: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
C C D E VDG D C EG A CP C P
Sbjct: 792 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 839
Query: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
+ C F G +YP G +D P C C G + C +R P C
Sbjct: 840 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 883
Query: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651
P C H + C + L L+ SVS R PC CA P R
Sbjct: 884 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 934
Query: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700
G C P C ++GKE+ G++ SP CH C+C GS C CA
Sbjct: 935 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 982
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
PC P G C +P C G GD R C++G C
Sbjct: 787 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 824
Query: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
PP + C P C +QG ++ G+ CH C +G +SC+ +A A
Sbjct: 825 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 881
Query: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758
A CP G+ +++ + E TC L R PC
Sbjct: 882 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924
Query: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814
GC+ P L+ G C P C + G G+ + P C C CQ GS +C
Sbjct: 925 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 979
Query: 815 PC 816
PC
Sbjct: 980 PC 981
Score = 50.8 bits (120), Expect = 1e-05
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372
C A +E PC A R ++ + CGV SR V PP+ + CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
+ C+C PG S D HC+ ++ R P CP G
Sbjct: 839 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 887
Query: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
VF C RTC Q L L+ PC+ GC CP GL+ H C PE
Sbjct: 888 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 944
Query: 1478 CP 1479
CP
Sbjct: 945 CP 946
Score = 50.8 bits (120), Expect = 1e-05
Identities = 52/185 (28%), Positives = 64/185 (34%), Gaps = 54/185 (29%)
Query: 771 CCPTCQ-GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPC 829
C P Q C + GV G D P+ C C++G M C + P A CP G
Sbjct: 837 CVPRNQCSCHFQGVDYPPG----DSDIPSLGHCHCKDGVMSCDSR-APAAACP---AGQV 888
Query: 830 F--CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERG 887
F C H+ L RE C L V+ RG
Sbjct: 889 FVNCSDLHTDLELSRERT----------------------------CEQQLLNLSVSARG 920
Query: 888 SCCPRC---RGCLAHG------EEHP---EGSRWVPPD---SACSSCVCHEGVVTCARIQ 932
C C +G L HG EE P +G + P D S C +CVC G C
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 980
Query: 933 CISSC 937
C S+C
Sbjct: 981 CASTC 985
Score = 50.4 bits (119), Expect = 1e-05
Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)
Query: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304
SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C
Sbjct: 691 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 747
Query: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
+C + H ++ FR + + C E S E C V PC
Sbjct: 748 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 800
Query: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396
AC +DG +E EG PD P C C +P
Sbjct: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860
Query: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454
G C ++ P A CP+ QV+ N + TD + S C Q
Sbjct: 861 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 913
Query: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
++ S + CA PQ G C CP +E F + S PC C C
Sbjct: 914 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 969
Query: 510 QEGHAHCQPRPC 521
Q G C PC
Sbjct: 970 QRGSFQCTLHPC 981
Score = 48.1 bits (113), Expect = 6e-05
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321
V GD S C G CPP + + +P C C +QG Y +
Sbjct: 807 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 856
Query: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375
+ + G C C+ G +SC+ + CP + S L EL E E
Sbjct: 857 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 910
Query: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
+ G + C C G+ + G P C CT+ + Y
Sbjct: 911 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 955
Query: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
G SPCH C CQ G+ C+L C T A
Sbjct: 956 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 987
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170
C C+DG C +A C GQ + N D TC + L +V +G
Sbjct: 865 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920
Query: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
P S C + G+ C + C CT G + G + +P C C C G QC
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 977
Query: 227 QRECASLC 234
CAS C
Sbjct: 978 LHPCASTC 985
Score = 44.7 bits (104), Expect = 7e-04
Identities = 93/393 (23%), Positives = 119/393 (30%), Gaps = 124/393 (31%)
Query: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
PLDP C + C C EG++ ++ ALC + C S G GE
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2447
Query: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ C +CQA + V L CP PR CL GE +
Sbjct: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2489
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPH--------DCCPQCSDCEHEGR 959
+P C C V C + C R G CCP S
Sbjct: 2490 LLLPTKDPC----CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS------- 2538
Query: 960 KYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCP 1017
C C+P C PS C Q+L G CC
Sbjct: 2539 -----------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCT 2571
Query: 1018 TCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCP 1077
+ A +C + + +CQ+ L +H+ EL CPL + C
Sbjct: 2572 SYFCACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCE 2612
Query: 1078 VCRAPTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS------ 1125
R P C G A E W+ D C SC C T+ RC S L
Sbjct: 2613 NFRCPQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHS 2669
Query: 1126 ----CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
CG K + P CL R M G
Sbjct: 2670 VENVCGCAKYECVK----APVCLSRELGVMQPG 2698
Score = 42.0 bits (97), Expect = 0.004
Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)
Query: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586
P +C DCS C + + + F P C L + VQ C+A C +
Sbjct: 2296 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2355
Query: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628
P L + C C P C + G E+ G+ C
Sbjct: 2356 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2411
Query: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683
+C +G++ +R L P A CA C S G A GE + S + C H
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2459
Query: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732
C + G S P++C P + CC LG + NQ
Sbjct: 2460 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2511
Query: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773
P R L T C CE P C L+PS CC
Sbjct: 2512 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2571
Query: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816
+ C C GE L + T C L C + RC + C
Sbjct: 2572 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2631
Query: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
P CP+ S C C P CH + + E G C
Sbjct: 2632 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2677
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925
+ +C P C R G + G+ E S D C + C +
Sbjct: 2678 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2724
Query: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976
+ + C C Q + P D C C + + F PGA
Sbjct: 2725 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2784
Query: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024
C C P G +R S + CPP + P + CC TC E
Sbjct: 2785 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2837
Query: 1025 NCSE 1028
+C +
Sbjct: 2838 SCKK 2841
Score = 39.3 bits (90), Expect = 0.029
Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)
Query: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990
++S Q R P C CS C R + F P CE+ I + + P +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2345
Query: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033
CH+ CP L + C T E C +G+LG
Sbjct: 2346 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2397
Query: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
P DP + CQ L C+ C E + L RH+ C P + + R
Sbjct: 2398 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2443
Query: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
A GE W S ++G + Q Q PD + G CP PRP SC+ F
Sbjct: 2444 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2485
Query: 1154 GD 1155
G+
Sbjct: 2486 GE 2487
Score = 37.7 bits (86), Expect = 0.084
Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)
Query: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172
AC C C AH H C ++G + P +C C P +
Sbjct: 740 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 795
Query: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215
C +L E+C G EC C ++ + + P + C
Sbjct: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 855
Query: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235
C C +G + C R A+ CP
Sbjct: 856 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 915
Query: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280
AR L G CP D CFL G+E+ G+ V S PC C C GS
Sbjct: 916 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 973
Query: 281 VQCEPLPC 288
QC PC
Sbjct: 974 FQCTLHPC 981
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725
K F E A+CH C + ++C P F G P CE+ G
Sbjct: 422 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 481
Query: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762
Y +E CN CTC G C C P CS
Sbjct: 482 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 514
Score = 36.6 bits (83), Expect = 0.19
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173
+ C C G G LP C+ G+ Y G + SP C TC C G+ QC C
Sbjct: 924 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 981
Query: 174 SELNCLESCTPPGE 187
+ +CT G+
Sbjct: 982 A-----STCTAYGD 990
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)
Query: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338
LP PP ++PG + G QC P D C H Y S F C CQ+
Sbjct: 329 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 380
Query: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386
G+V+ C CA P G RQ C+ + E + P P
Sbjct: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 440
Query: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441
+CV C DG ++ C P + CP C +H +Y G +
Sbjct: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 490
Query: 442 DSPCHACHCQDGTVTCSLVDCP 463
C+ C C G CS CP
Sbjct: 491 --DCNTCTCTSGKWECSTAVCP 510
Score = 35.4 bits (80), Expect = 0.42
Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)
Query: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233
C+ +C PP C + G + C++ C C EG I R+ ++L
Sbjct: 2381 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2426
Query: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289
C +P C D G GE S C H A ++ L CP
Sbjct: 2427 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477
Query: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334
P C G++ CC VC+ +G + RL QE C
Sbjct: 2478 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2537
Query: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394
SC+ CE + L P+C D Q GR +C
Sbjct: 2538 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2569
Query: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
C + C C P P C ++ T H +N T+ P + C C++
Sbjct: 2570 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2613
Query: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503
C V C T P +CCP C P C L E+ +D E F H
Sbjct: 2614 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2668
Query: 504 CQECRCQEGHAHCQPRPCPRAP 525
E C C +AP
Sbjct: 2669 -----SVENVCGCAKYECVKAP 2685
Score = 33.5 bits (75), Expect = 1.6
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)
Query: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
+CT+ +CQ D A C +A + R C+Q G+ T CT V C+
Sbjct: 372 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 420
Query: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
+ + C+ CCP C S C++ I C
Sbjct: 421 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 452
Query: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
CP G C P C +G + G V + C+ C C +G +C C
Sbjct: 453 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 509
Query: 289 P 289
P
Sbjct: 510 P 510
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801
C C G + E GC P CP C +HG G + + C+
Sbjct: 454 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 494
Query: 802 CTCQEGSMRCQKKPCP 817
CTC G C CP
Sbjct: 495 CTCTSGKWECSTAVCP 510
Score = 33.1 bits (74), Expect = 2.1
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)
Query: 1426 FDECGPPCPRTCFNQHIPLGELAAHCV-----RPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
+D C PC +TC + AA C R CVP C P L E C+ E C +
Sbjct: 1412 YDACASPCFQTCRDPR------AASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVE 1465
Query: 1481 -VLLTGDQPLGARPSPSREPQETP 1503
+ + LG P + TP
Sbjct: 1466 PAVWVPTEALGNETLPPSQGLPTP 1489
Score = 32.7 bits (73), Expect = 2.7
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)
Query: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442
CT+ +CQ D C A+ C +P CT H + A N A
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495
P +CH C D + C VD CP + G CP C ++ G
Sbjct: 433 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 485
Query: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
S ++ C C C G C CP A C+
Sbjct: 486 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 514
Score = 32.7 bits (73), Expect = 2.7
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622
+C+A C P C P + E C C P GC P PPG
Sbjct: 428 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 485
Query: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648
+ C C C G C C PA C+
Sbjct: 486 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 514
Score = 32.0 bits (71), Expect = 4.6
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906
PA C +++CV CP + E G C CP C HG +P G
Sbjct: 434 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 485
Query: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938
S V D C++C C G C+ C + C+
Sbjct: 486 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 514
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 160 bits (406), Expect = 7e-39
Identities = 133/430 (30%), Positives = 182/430 (42%), Gaps = 50/430 (11%)
Query: 1083 TQSCVHQGREVASGERWTV-----DTCTSCSCMAGTVRCQSQRCSP---LSCGPDKAPAL 1134
+ S HQ +A G++ TV + S + + R +C+P SC + +
Sbjct: 62 SSSSSHQEATLAMGDKATVVGGQAEAPDSVAMSSWERRLHRAKCAPSYLFSCF-NGGECV 120
Query: 1135 SPGSC-C-------PRCL-------PRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA-- 1177
P C C PRC R + C A+G H TFDG + G SY L
Sbjct: 121 HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180
Query: 1178 KDCHSGDFSVHVTNDDR-GRSGVAWTQEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQ 1235
+ FS+ V ND + G S ++ V++ +G+ + L ++ VT G V LP +
Sbjct: 181 HEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVM 238
Query: 1236 EPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQG 1295
+L G+ ++ H Q + WDG S V + + G T GLCGN N +DDL
Sbjct: 239 GSARLQQLAGYVIVRH-QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVT 297
Query: 1296 PEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPF 1355
G L F +SWQ P P ++ PC + +C L PF
Sbjct: 298 SSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPF 357
Query: 1356 SRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-T 1412
CHA V P PF A+C DLC S D A C AL YA C QAG WR
Sbjct: 358 DACHAYVSPLPFTASCTSDLCQ----SMGDVATWCRALAEYARACAQAGRPLQGWRTQLR 413
Query: 1413 LCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR---PCVPGCQCPAGLVEHE 1469
C V C E+ F ++EC CP +C + A CV CV GC CP GL+ +
Sbjct: 414 QCTVHCK-EKAFTYNECIACCPASCHPR--------ASCVDSEIACVDGCYCPNGLIFED 464
Query: 1470 AHCIPPEACP 1479
C+ P CP
Sbjct: 465 GGCVAPAECP 474
Score = 160 bits (405), Expect = 9e-39
Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)
Query: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902
F P E CR C+ GQ C L C+ L V R R C E
Sbjct: 726 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 781
Query: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949
E S V P D A +G +R +C+ CA P D C P
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
QCS C +G Y PG+S P C C+ +G S C R
Sbjct: 842 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 877
Query: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
P CP + NCS+ EL+ C Q L L + P LS
Sbjct: 878 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 924
Query: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120
G CP C P + C +G+E G++ + C +C C G+ +C
Sbjct: 925 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 980
Query: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180
C+ ++C A+GD HYRTFDG F G+C L K
Sbjct: 981 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015
Query: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240
FSV V N + SG+ + +++ +G+ + D G+P FL +
Sbjct: 1016 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 1070
Query: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE
Sbjct: 1071 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1130
Query: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356
L L + FG+SW E +DP RE A C +L S F
Sbjct: 1131 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1181
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416
CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC
Sbjct: 1182 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1240
Query: 1417 GC 1418
C
Sbjct: 1241 DC 1242
Score = 159 bits (403), Expect = 1e-38
Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)
Query: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102
C +C P SC SE G CP C AP + C G G D
Sbjct: 432 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 491
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
C +C+C +G C + C PA C GD H+ TFD
Sbjct: 492 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 525
Query: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218
GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q
Sbjct: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 585
Query: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276
G V + D + + P+ + L + + G++VL+D + ++ + V +
Sbjct: 586 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332
T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 702
Query: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
+AA Y + C VL F+ C A + P P+F C D C CG CLC L
Sbjct: 703 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 752
Query: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445
YA CR+ G+ +R C + C E + C PC RTC + P
Sbjct: 753 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 810
Query: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496
+L+ CV GC CP L C+P C D P G PS
Sbjct: 811 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861
Score = 84.3 bits (207), Expect = 8e-16
Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)
Query: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154
C C+ G +R QSQ C +P CG A + CCP C R C F
Sbjct: 2059 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2115
Query: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211
D + TFDG + Y+L++ +VHV + G + W V+L
Sbjct: 2116 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2174
Query: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265
+A ++ D VTVD PV P + +E GH ++ +Q+ W G
Sbjct: 2175 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2233
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322
VE S QG GLCG +G A +DL +G ++ A F +SWQV L
Sbjct: 2234 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2286
Query: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379
S G+ D C A + + ++ + FS CH VPPE F + D
Sbjct: 2287 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2335
Query: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437
+ C AL Y + C + V WR C C + + C C P+TC
Sbjct: 2336 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2391
Query: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
Q LG L + GC C G + H H CIP C
Sbjct: 2392 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433
Score = 58.5 bits (140), Expect = 5e-08
Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)
Query: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
C C D E VDG D C EG A CP C P
Sbjct: 792 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 839
Query: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
+ C F G +YP G +D P C C G + C +R P C
Sbjct: 840 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 883
Query: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651
P C H + C + L L+ SVS R PC CA P R
Sbjct: 884 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 934
Query: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700
G C P C ++GKE+ G++ SP CH C+C GS C CA
Sbjct: 935 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 982
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
PC P G C +P C G GD R C++G C
Sbjct: 787 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 824
Query: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
PP + C P C +QG ++ G+ CH C +G +SC+ +A A
Sbjct: 825 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 881
Query: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758
A CP G+ +++ + E TC L R PC
Sbjct: 882 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924
Query: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814
GC+ P L+ G C P C + G G+ + P C C CQ GS +C
Sbjct: 925 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 979
Query: 815 PC 816
PC
Sbjct: 980 PC 981
Score = 50.8 bits (120), Expect = 1e-05
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372
C A +E PC A R ++ + CGV SR V PP+ + CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
+ C+C PG S D HC+ ++ R P CP G
Sbjct: 839 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 887
Query: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
VF C RTC Q L L+ PC+ GC CP GL+ H C PE
Sbjct: 888 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 944
Query: 1478 CP 1479
CP
Sbjct: 945 CP 946
Score = 50.8 bits (120), Expect = 1e-05
Identities = 52/185 (28%), Positives = 64/185 (34%), Gaps = 54/185 (29%)
Query: 771 CCPTCQ-GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPC 829
C P Q C + GV G D P+ C C++G M C + P A CP G
Sbjct: 837 CVPRNQCSCHFQGVDYPPG----DSDIPSLGHCHCKDGVMSCDSR-APAAACP---AGQV 888
Query: 830 F--CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERG 887
F C H+ L RE C L V+ RG
Sbjct: 889 FVNCSDLHTDLELSRERT----------------------------CEQQLLNLSVSARG 920
Query: 888 SCCPRC---RGCLAHG------EEHP---EGSRWVPPD---SACSSCVCHEGVVTCARIQ 932
C C +G L HG EE P +G + P D S C +CVC G C
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 980
Query: 933 CISSC 937
C S+C
Sbjct: 981 CASTC 985
Score = 50.4 bits (119), Expect = 1e-05
Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)
Query: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304
SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C
Sbjct: 691 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 747
Query: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
+C + H ++ FR + + C E S E C V PC
Sbjct: 748 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 800
Query: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396
AC +DG +E EG PD P C C +P
Sbjct: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860
Query: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454
G C ++ P A CP+ QV+ N + TD + S C Q
Sbjct: 861 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 913
Query: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
++ S + CA PQ G C CP +E F + S PC C C
Sbjct: 914 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 969
Query: 510 QEGHAHCQPRPC 521
Q G C PC
Sbjct: 970 QRGSFQCTLHPC 981
Score = 48.1 bits (113), Expect = 6e-05
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321
V GD S C G CPP + + +P C C +QG Y +
Sbjct: 807 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 856
Query: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375
+ + G C C+ G +SC+ + CP + S L EL E E
Sbjct: 857 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 910
Query: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
+ G + C C G+ + G P C CT+ + Y
Sbjct: 911 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 955
Query: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
G SPCH C CQ G+ C+L C T A
Sbjct: 956 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 987
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170
C C+DG C +A C GQ + N D TC + L +V +G
Sbjct: 865 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920
Query: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
P S C + G+ C + C CT G + G + +P C C C G QC
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 977
Query: 227 QRECASLC 234
CAS C
Sbjct: 978 LHPCASTC 985
Score = 44.7 bits (104), Expect = 7e-04
Identities = 93/393 (23%), Positives = 119/393 (30%), Gaps = 124/393 (31%)
Query: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
PLDP C + C C EG++ ++ ALC + C S G GE
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2447
Query: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ C +CQA + V L CP PR CL GE +
Sbjct: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2489
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPH--------DCCPQCSDCEHEGR 959
+P C C V C + C R G CCP S
Sbjct: 2490 LLLPTKDPC----CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS------- 2538
Query: 960 KYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCP 1017
C C+P C PS C Q+L G CC
Sbjct: 2539 -----------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCT 2571
Query: 1018 TCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCP 1077
+ A +C + + +CQ+ L +H+ EL CPL + C
Sbjct: 2572 SYFCACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCE 2612
Query: 1078 VCRAPTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS------ 1125
R P C G A E W+ D C SC C T+ RC S L
Sbjct: 2613 NFRCPQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHS 2669
Query: 1126 ----CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
CG K + P CL R M G
Sbjct: 2670 VENVCGCAKYECVK----APVCLSRELGVMQPG 2698
Score = 42.0 bits (97), Expect = 0.004
Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)
Query: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586
P +C DCS C + + + F P C L + VQ C+A C +
Sbjct: 2296 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2355
Query: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628
P L + C C P C + G E+ G+ C
Sbjct: 2356 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2411
Query: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683
+C +G++ +R L P A CA C S G A GE + S + C H
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2459
Query: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732
C + G S P++C P + CC LG + NQ
Sbjct: 2460 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2511
Query: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773
P R L T C CE P C L+PS CC
Sbjct: 2512 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2571
Query: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816
+ C C GE L + T C L C + RC + C
Sbjct: 2572 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2631
Query: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
P CP+ S C C P CH + + E G C
Sbjct: 2632 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2677
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925
+ +C P C R G + G+ E S D C + C +
Sbjct: 2678 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2724
Query: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976
+ + C C Q + P D C C + + F PGA
Sbjct: 2725 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2784
Query: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024
C C P G +R S + CPP + P + CC TC E
Sbjct: 2785 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2837
Query: 1025 NCSE 1028
+C +
Sbjct: 2838 SCKK 2841
Score = 39.3 bits (90), Expect = 0.029
Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)
Query: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990
++S Q R P C CS C R + F P CE+ I + + P +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2345
Query: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033
CH+ CP L + C T E C +G+LG
Sbjct: 2346 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2397
Query: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
P DP + CQ L C+ C E + L RH+ C P + + R
Sbjct: 2398 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2443
Query: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
A GE W S ++G + Q Q PD + G CP PRP SC+ F
Sbjct: 2444 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2485
Query: 1154 GD 1155
G+
Sbjct: 2486 GE 2487
Score = 37.7 bits (86), Expect = 0.084
Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)
Query: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172
AC C C AH H C ++G + P +C C P +
Sbjct: 740 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 795
Query: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215
C +L E+C G EC C ++ + + P + C
Sbjct: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 855
Query: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235
C C +G + C R A+ CP
Sbjct: 856 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 915
Query: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280
AR L G CP D CFL G+E+ G+ V S PC C C GS
Sbjct: 916 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 973
Query: 281 VQCEPLPC 288
QC PC
Sbjct: 974 FQCTLHPC 981
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725
K F E A+CH C + ++C P F G P CE+ G
Sbjct: 422 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 481
Query: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762
Y +E CN CTC G C C P CS
Sbjct: 482 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 514
Score = 36.6 bits (83), Expect = 0.19
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173
+ C C G G LP C+ G+ Y G + SP C TC C G+ QC C
Sbjct: 924 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 981
Query: 174 SELNCLESCTPPGE 187
+ +CT G+
Sbjct: 982 A-----STCTAYGD 990
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)
Query: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338
LP PP ++PG + G QC P D C H Y S F C CQ+
Sbjct: 329 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 380
Query: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386
G+V+ C CA P G RQ C+ + E + P P
Sbjct: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 440
Query: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441
+CV C DG ++ C P + CP C +H +Y G +
Sbjct: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 490
Query: 442 DSPCHACHCQDGTVTCSLVDCP 463
C+ C C G CS CP
Sbjct: 491 --DCNTCTCTSGKWECSTAVCP 510
Score = 35.4 bits (80), Expect = 0.42
Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)
Query: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233
C+ +C PP C + G + C++ C C EG I R+ ++L
Sbjct: 2381 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2426
Query: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289
C +P C D G GE S C H A ++ L CP
Sbjct: 2427 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477
Query: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334
P C G++ CC VC+ +G + RL QE C
Sbjct: 2478 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2537
Query: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394
SC+ CE + L P+C D Q GR +C
Sbjct: 2538 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2569
Query: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
C + C C P P C ++ T H +N T+ P + C C++
Sbjct: 2570 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2613
Query: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503
C V C T P +CCP C P C L E+ +D E F H
Sbjct: 2614 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2668
Query: 504 CQECRCQEGHAHCQPRPCPRAP 525
E C C +AP
Sbjct: 2669 -----SVENVCGCAKYECVKAP 2685
Score = 33.5 bits (75), Expect = 1.6
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)
Query: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
+CT+ +CQ D A C +A + R C+Q G+ T CT V C+
Sbjct: 372 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 420
Query: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
+ + C+ CCP C S C++ I C
Sbjct: 421 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 452
Query: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
CP G C P C +G + G V + C+ C C +G +C C
Sbjct: 453 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 509
Query: 289 P 289
P
Sbjct: 510 P 510
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801
C C G + E GC P CP C +HG G + + C+
Sbjct: 454 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 494
Query: 802 CTCQEGSMRCQKKPCP 817
CTC G C CP
Sbjct: 495 CTCTSGKWECSTAVCP 510
Score = 33.1 bits (74), Expect = 2.1
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)
Query: 1426 FDECGPPCPRTCFNQHIPLGELAAHCV-----RPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
+D C PC +TC + AA C R CVP C P L E C+ E C +
Sbjct: 1412 YDACASPCFQTCRDPR------AASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVE 1465
Query: 1481 -VLLTGDQPLGARPSPSREPQETP 1503
+ + LG P + TP
Sbjct: 1466 PAVWVPTEALGNETLPPSQGLPTP 1489
Score = 32.7 bits (73), Expect = 2.7
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)
Query: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442
CT+ +CQ D C A+ C +P CT H + A N A
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495
P +CH C D + C VD CP + G CP C ++ G
Sbjct: 433 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 485
Query: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
S ++ C C C G C CP A C+
Sbjct: 486 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 514
Score = 32.7 bits (73), Expect = 2.7
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622
+C+A C P C P + E C C P GC P PPG
Sbjct: 428 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 485
Query: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648
+ C C C G C C PA C+
Sbjct: 486 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 514
Score = 32.0 bits (71), Expect = 4.6
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906
PA C +++CV CP + E G C CP C HG +P G
Sbjct: 434 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 485
Query: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938
S V D C++C C G C+ C + C+
Sbjct: 486 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 514
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 160 bits (405), Expect = 9e-39
Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)
Query: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902
F P E CR C+ GQ C L C+ L V R R C E
Sbjct: 654 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 709
Query: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949
E S V P D A +G +R +C+ CA P D C P
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
QCS C +G Y PG+S P C C+ +G S C R
Sbjct: 770 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 805
Query: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
P CP + NCS+ EL+ C Q L L + P LS
Sbjct: 806 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 852
Query: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120
G CP C P + C +G+E G++ + C +C C G+ +C
Sbjct: 853 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 908
Query: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180
C+ ++C A+GD HYRTFDG F G+C L K
Sbjct: 909 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
Query: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240
FSV V N + SG+ + +++ +G+ + D G+P FL +
Sbjct: 944 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 998
Query: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE
Sbjct: 999 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1058
Query: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356
L L + FG+SW E +DP RE A C +L S F
Sbjct: 1059 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1109
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416
CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC
Sbjct: 1110 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1168
Query: 1417 GC 1418
C
Sbjct: 1169 DC 1170
Score = 159 bits (403), Expect = 1e-38
Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)
Query: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102
C +C P SC SE G CP C AP + C G G D
Sbjct: 360 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 419
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
C +C+C +G C + C PA C GD H+ TFD
Sbjct: 420 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 453
Query: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218
GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q
Sbjct: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 513
Query: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276
G V + D + + P+ + L + + G++VL+D + ++ + V +
Sbjct: 514 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332
T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 630
Query: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
+AA Y + C VL F+ C A + P P+F C D C CG CLC L
Sbjct: 631 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 680
Query: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445
YA CR+ G+ +R C + C E + C PC RTC + P
Sbjct: 681 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 738
Query: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496
+L+ CV GC CP L C+P C D P G PS
Sbjct: 739 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789
Score = 158 bits (400), Expect = 3e-38
Identities = 114/344 (33%), Positives = 152/344 (44%), Gaps = 26/344 (7%)
Query: 1146 RPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA--KDCHSGDFSVHVTNDDR-GRSGVAWT 1202
R + C A+G H TFDG + G SY L + FS+ V ND + G S +
Sbjct: 75 RDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
Query: 1203 QEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD 1261
+ V++ +G+ + L ++ VT G V LP + +L G+ ++ H Q + WD
Sbjct: 135 RAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRH-QSAFTLAWD 191
Query: 1262 GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR 1321
G S V + + G T GLCGN N +DDL G L F +SWQ P
Sbjct: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
Query: 1322 PCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPG 1381
P ++ PC + +C L PF CHA V P PF A+C DLC
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ---- 307
Query: 1382 SSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCF 1438
S D A C AL YA C QAG WR C V C E+ F ++EC CP +C
Sbjct: 308 SMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK-EKAFTYNECIACCPASCH 366
Query: 1439 NQHIPLGELAAHCVR---PCVPGCQCPAGLVEHEAHCIPPEACP 1479
+ A CV CV GC CP GL+ + C+ P CP
Sbjct: 367 PR--------ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
Score = 84.3 bits (207), Expect = 8e-16
Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)
Query: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154
C C+ G +R QSQ C +P CG A + CCP C R C F
Sbjct: 1987 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2043
Query: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211
D + TFDG + Y+L++ +VHV + G + W V+L
Sbjct: 2044 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2102
Query: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265
+A ++ D VTVD PV P + +E GH ++ +Q+ W G
Sbjct: 2103 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322
VE S QG GLCG +G A +DL +G ++ A F +SWQV L
Sbjct: 2162 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2214
Query: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379
S G+ D C A + + ++ + FS CH VPPE F + D
Sbjct: 2215 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2263
Query: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437
+ C AL Y + C + V WR C C + + C C P+TC
Sbjct: 2264 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2319
Query: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
Q LG L + GC C G + H H CIP C
Sbjct: 2320 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
Score = 58.5 bits (140), Expect = 5e-08
Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)
Query: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
C C D E VDG D C EG A CP C P
Sbjct: 720 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 767
Query: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
+ C F G +YP G +D P C C G + C +R P C
Sbjct: 768 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 811
Query: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651
P C H + C + L L+ SVS R PC CA P R
Sbjct: 812 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 862
Query: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700
G C P C ++GKE+ G++ SP CH C+C GS C CA
Sbjct: 863 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 910
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
PC P G C +P C G GD R C++G C
Sbjct: 715 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 752
Query: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
PP + C P C +QG ++ G+ CH C +G +SC+ +A A
Sbjct: 753 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 809
Query: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758
A CP G+ +++ + E TC L R PC
Sbjct: 810 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
Query: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814
GC+ P L+ G C P C + G G+ + P C C CQ GS +C
Sbjct: 853 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 907
Query: 815 PC 816
PC
Sbjct: 908 PC 909
Score = 50.8 bits (120), Expect = 1e-05
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372
C A +E PC A R ++ + CGV SR V PP+ + CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
+ C+C PG S D HC+ ++ R P CP G
Sbjct: 767 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 815
Query: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
VF C RTC Q L L+ PC+ GC CP GL+ H C PE
Sbjct: 816 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 872
Query: 1478 CP 1479
CP
Sbjct: 873 CP 874
Score = 50.8 bits (120), Expect = 1e-05
Identities = 52/185 (28%), Positives = 64/185 (34%), Gaps = 54/185 (29%)
Query: 771 CCPTCQ-GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPC 829
C P Q C + GV G D P+ C C++G M C + P A CP G
Sbjct: 765 CVPRNQCSCHFQGVDYPPG----DSDIPSLGHCHCKDGVMSCDSR-APAAACP---AGQV 816
Query: 830 F--CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERG 887
F C H+ L RE C L V+ RG
Sbjct: 817 FVNCSDLHTDLELSRERT----------------------------CEQQLLNLSVSARG 848
Query: 888 SCCPRC---RGCLAHG------EEHP---EGSRWVPPD---SACSSCVCHEGVVTCARIQ 932
C C +G L HG EE P +G + P D S C +CVC G C
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 908
Query: 933 CISSC 937
C S+C
Sbjct: 909 CASTC 913
Score = 50.4 bits (119), Expect = 1e-05
Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)
Query: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304
SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C
Sbjct: 619 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 675
Query: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
+C + H ++ FR + + C E S E C V PC
Sbjct: 676 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 728
Query: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396
AC +DG +E EG PD P C C +P
Sbjct: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
Query: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454
G C ++ P A CP+ QV+ N + TD + S C Q
Sbjct: 789 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 841
Query: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
++ S + CA PQ G C CP +E F + S PC C C
Sbjct: 842 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 897
Query: 510 QEGHAHCQPRPC 521
Q G C PC
Sbjct: 898 QRGSFQCTLHPC 909
Score = 48.1 bits (113), Expect = 6e-05
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321
V GD S C G CPP + + +P C C +QG Y +
Sbjct: 735 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 784
Query: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375
+ + G C C+ G +SC+ + CP + S L EL E E
Sbjct: 785 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 838
Query: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
+ G + C C G+ + G P C CT+ + Y
Sbjct: 839 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 883
Query: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
G SPCH C CQ G+ C+L C T A
Sbjct: 884 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 915
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170
C C+DG C +A C GQ + N D TC + L +V +G
Sbjct: 793 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848
Query: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
P S C + G+ C + C CT G + G + +P C C C G QC
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 905
Query: 227 QRECASLC 234
CAS C
Sbjct: 906 LHPCASTC 913
Score = 44.7 bits (104), Expect = 7e-04
Identities = 93/393 (23%), Positives = 119/393 (30%), Gaps = 124/393 (31%)
Query: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
PLDP C + C C EG++ ++ ALC + C S G GE
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2375
Query: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ C +CQA + V L CP PR CL GE +
Sbjct: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2417
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPH--------DCCPQCSDCEHEGR 959
+P C C V C + C R G CCP S
Sbjct: 2418 LLLPTKDPC----CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS------- 2466
Query: 960 KYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCP 1017
C C+P C PS C Q+L G CC
Sbjct: 2467 -----------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCT 2499
Query: 1018 TCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCP 1077
+ A +C + + +CQ+ L +H+ EL CPL + C
Sbjct: 2500 SYFCACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCE 2540
Query: 1078 VCRAPTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS------ 1125
R P C G A E W+ D C SC C T+ RC S L
Sbjct: 2541 NFRCPQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHS 2597
Query: 1126 ----CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
CG K + P CL R M G
Sbjct: 2598 VENVCGCAKYECVK----APVCLSRELGVMQPG 2626
Score = 42.0 bits (97), Expect = 0.004
Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)
Query: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586
P +C DCS C + + + F P C L + VQ C+A C +
Sbjct: 2224 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2283
Query: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628
P L + C C P C + G E+ G+ C
Sbjct: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2339
Query: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683
+C +G++ +R L P A CA C S G A GE + S + C H
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2387
Query: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732
C + G S P++C P + CC LG + NQ
Sbjct: 2388 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2439
Query: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773
P R L T C CE P C L+PS CC
Sbjct: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2499
Query: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816
+ C C GE L + T C L C + RC + C
Sbjct: 2500 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2559
Query: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
P CP+ S C C P CH + + E G C
Sbjct: 2560 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2605
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925
+ +C P C R G + G+ E S D C + C +
Sbjct: 2606 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2652
Query: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976
+ + C C Q + P D C C + + F PGA
Sbjct: 2653 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2712
Query: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024
C C P G +R S + CPP + P + CC TC E
Sbjct: 2713 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2765
Query: 1025 NCSE 1028
+C +
Sbjct: 2766 SCKK 2769
Score = 39.3 bits (90), Expect = 0.029
Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)
Query: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990
++S Q R P C CS C R + F P CE+ I + + P +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2273
Query: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033
CH+ CP L + C T E C +G+LG
Sbjct: 2274 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2325
Query: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
P DP + CQ L C+ C E + L RH+ C P + + R
Sbjct: 2326 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2371
Query: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
A GE W S ++G + Q Q PD + G CP PRP SC+ F
Sbjct: 2372 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2413
Query: 1154 GD 1155
G+
Sbjct: 2414 GE 2415
Score = 37.7 bits (86), Expect = 0.084
Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)
Query: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172
AC C C AH H C ++G + P +C C P +
Sbjct: 668 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 723
Query: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215
C +L E+C G EC C ++ + + P + C
Sbjct: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 783
Query: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235
C C +G + C R A+ CP
Sbjct: 784 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 843
Query: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280
AR L G CP D CFL G+E+ G+ V S PC C C GS
Sbjct: 844 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 901
Query: 281 VQCEPLPC 288
QC PC
Sbjct: 902 FQCTLHPC 909
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725
K F E A+CH C + ++C P F G P CE+ G
Sbjct: 350 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 409
Query: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762
Y +E CN CTC G C C P CS
Sbjct: 410 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 442
Score = 36.6 bits (83), Expect = 0.19
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173
+ C C G G LP C+ G+ Y G + SP C TC C G+ QC C
Sbjct: 852 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 909
Query: 174 SELNCLESCTPPGE 187
+ +CT G+
Sbjct: 910 A-----STCTAYGD 918
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)
Query: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338
LP PP ++PG + G QC P D C H Y S F C CQ+
Sbjct: 257 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 308
Query: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386
G+V+ C CA P G RQ C+ + E + P P
Sbjct: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 368
Query: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441
+CV C DG ++ C P + CP C +H +Y G +
Sbjct: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 418
Query: 442 DSPCHACHCQDGTVTCSLVDCP 463
C+ C C G CS CP
Sbjct: 419 --DCNTCTCTSGKWECSTAVCP 438
Score = 35.4 bits (80), Expect = 0.42
Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)
Query: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233
C+ +C PP C + G + C++ C C EG I R+ ++L
Sbjct: 2309 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2354
Query: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289
C +P C D G GE S C H A ++ L CP
Sbjct: 2355 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
Query: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334
P C G++ CC VC+ +G + RL QE C
Sbjct: 2406 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2465
Query: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394
SC+ CE + L P+C D Q GR +C
Sbjct: 2466 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2497
Query: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
C + C C P P C ++ T H +N T+ P + C C++
Sbjct: 2498 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2541
Query: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503
C V C T P +CCP C P C L E+ +D E F H
Sbjct: 2542 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2596
Query: 504 CQECRCQEGHAHCQPRPCPRAP 525
E C C +AP
Sbjct: 2597 -----SVENVCGCAKYECVKAP 2613
Score = 33.5 bits (75), Expect = 1.6
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)
Query: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
+CT+ +CQ D A C +A + R C+Q G+ T CT V C+
Sbjct: 300 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 348
Query: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
+ + C+ CCP C S C++ I C
Sbjct: 349 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 380
Query: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
CP G C P C +G + G V + C+ C C +G +C C
Sbjct: 381 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 437
Query: 289 P 289
P
Sbjct: 438 P 438
Score = 33.5 bits (75), Expect = 1.6
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)
Query: 1426 FDECGPPCPRTCFNQHIPLGELAAHC-----VRPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
+D C PC +TC + AA C V CVP C P L E C+ E C +
Sbjct: 1340 YDACASPCFQTCRDPR------AASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393
Query: 1481 -VLLTGDQPLGARPSPSREPQETP 1503
+ + LG P + TP
Sbjct: 1394 PAVWVPTEALGNETLPPSQGLPTP 1417
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801
C C G + E GC P CP C +HG G + + C+
Sbjct: 382 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 422
Query: 802 CTCQEGSMRCQKKPCP 817
CTC G C CP
Sbjct: 423 CTCTSGKWECSTAVCP 438
Score = 32.7 bits (73), Expect = 2.7
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)
Query: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442
CT+ +CQ D C A+ C +P CT H + A N A
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495
P +CH C D + C VD CP + G CP C ++ G
Sbjct: 361 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 413
Query: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
S ++ C C C G C CP A C+
Sbjct: 414 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 442
Score = 32.7 bits (73), Expect = 2.7
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622
+C+A C P C P + E C C P GC P PPG
Sbjct: 356 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 413
Query: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648
+ C C C G C C PA C+
Sbjct: 414 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
Score = 32.0 bits (71), Expect = 4.6
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906
PA C +++CV CP + E G C CP C HG +P G
Sbjct: 362 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 413
Query: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938
S V D C++C C G C+ C + C+
Sbjct: 414 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 442
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 160 bits (405), Expect = 9e-39
Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)
Query: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902
F P E CR C+ GQ C L C+ L V R R C E
Sbjct: 654 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 709
Query: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949
E S V P D A +G +R +C+ CA P D C P
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
QCS C +G Y PG+S P C C+ +G S C R
Sbjct: 770 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 805
Query: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
P CP + NCS+ EL+ C Q L L + P LS
Sbjct: 806 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 852
Query: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120
G CP C P + C +G+E G++ + C +C C G+ +C
Sbjct: 853 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 908
Query: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180
C+ ++C A+GD HYRTFDG F G+C L K
Sbjct: 909 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
Query: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240
FSV V N + SG+ + +++ +G+ + D G+P FL +
Sbjct: 944 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 998
Query: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE
Sbjct: 999 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1058
Query: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356
L L + FG+SW E +DP RE A C +L S F
Sbjct: 1059 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1109
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416
CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC
Sbjct: 1110 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1168
Query: 1417 GC 1418
C
Sbjct: 1169 DC 1170
Score = 159 bits (403), Expect = 1e-38
Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)
Query: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102
C +C P SC SE G CP C AP + C G G D
Sbjct: 360 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 419
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
C +C+C +G C + C PA C GD H+ TFD
Sbjct: 420 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 453
Query: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218
GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q
Sbjct: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 513
Query: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276
G V + D + + P+ + L + + G++VL+D + ++ + V +
Sbjct: 514 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332
T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 630
Query: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
+AA Y + C VL F+ C A + P P+F C D C CG CLC L
Sbjct: 631 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 680
Query: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445
YA CR+ G+ +R C + C E + C PC RTC + P
Sbjct: 681 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 738
Query: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496
+L+ CV GC CP L C+P C D P G PS
Sbjct: 739 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789
Score = 158 bits (400), Expect = 3e-38
Identities = 114/344 (33%), Positives = 152/344 (44%), Gaps = 26/344 (7%)
Query: 1146 RPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA--KDCHSGDFSVHVTNDDR-GRSGVAWT 1202
R + C A+G H TFDG + G SY L + FS+ V ND + G S +
Sbjct: 75 RDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
Query: 1203 QEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD 1261
+ V++ +G+ + L ++ VT G V LP + +L G+ ++ H Q + WD
Sbjct: 135 RAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRH-QSAFTLAWD 191
Query: 1262 GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR 1321
G S V + + G T GLCGN N +DDL G L F +SWQ P
Sbjct: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
Query: 1322 PCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPG 1381
P ++ PC + +C L PF CHA V P PF A+C DLC
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ---- 307
Query: 1382 SSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCF 1438
S D A C AL YA C QAG WR C V C E+ F ++EC CP +C
Sbjct: 308 SMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK-EKAFTYNECIACCPASCH 366
Query: 1439 NQHIPLGELAAHCVR---PCVPGCQCPAGLVEHEAHCIPPEACP 1479
+ A CV CV GC CP GL+ + C+ P CP
Sbjct: 367 PR--------ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
Score = 84.3 bits (207), Expect = 8e-16
Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)
Query: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154
C C+ G +R QSQ C +P CG A + CCP C R C F
Sbjct: 1987 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2043
Query: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211
D + TFDG + Y+L++ +VHV + G + W V+L
Sbjct: 2044 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2102
Query: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265
+A ++ D VTVD PV P + +E GH ++ +Q+ W G
Sbjct: 2103 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322
VE S QG GLCG +G A +DL +G ++ A F +SWQV L
Sbjct: 2162 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2214
Query: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379
S G+ D C A + + ++ + FS CH VPPE F + D
Sbjct: 2215 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2263
Query: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437
+ C AL Y + C + V WR C C + + C C P+TC
Sbjct: 2264 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2319
Query: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
Q LG L + GC C G + H H CIP C
Sbjct: 2320 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
Score = 58.5 bits (140), Expect = 5e-08
Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)
Query: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
C C D E VDG D C EG A CP C P
Sbjct: 720 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 767
Query: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
+ C F G +YP G +D P C C G + C +R P C
Sbjct: 768 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 811
Query: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651
P C H + C + L L+ SVS R PC CA P R
Sbjct: 812 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 862
Query: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700
G C P C ++GKE+ G++ SP CH C+C GS C CA
Sbjct: 863 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 910
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
PC P G C +P C G GD R C++G C
Sbjct: 715 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 752
Query: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
PP + C P C +QG ++ G+ CH C +G +SC+ +A A
Sbjct: 753 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 809
Query: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758
A CP G+ +++ + E TC L R PC
Sbjct: 810 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
Query: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814
GC+ P L+ G C P C + G G+ + P C C CQ GS +C
Sbjct: 853 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 907
Query: 815 PC 816
PC
Sbjct: 908 PC 909
Score = 50.8 bits (120), Expect = 1e-05
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372
C A +E PC A R ++ + CGV SR V PP+ + CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
+ C+C PG S D HC+ ++ R P CP G
Sbjct: 767 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 815
Query: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
VF C RTC Q L L+ PC+ GC CP GL+ H C PE
Sbjct: 816 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 872
Query: 1478 CP 1479
CP
Sbjct: 873 CP 874
Score = 50.8 bits (120), Expect = 1e-05
Identities = 52/185 (28%), Positives = 64/185 (34%), Gaps = 54/185 (29%)
Query: 771 CCPTCQ-GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPC 829
C P Q C + GV G D P+ C C++G M C + P A CP G
Sbjct: 765 CVPRNQCSCHFQGVDYPPG----DSDIPSLGHCHCKDGVMSCDSR-APAAACP---AGQV 816
Query: 830 F--CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERG 887
F C H+ L RE C L V+ RG
Sbjct: 817 FVNCSDLHTDLELSRERT----------------------------CEQQLLNLSVSARG 848
Query: 888 SCCPRC---RGCLAHG------EEHP---EGSRWVPPD---SACSSCVCHEGVVTCARIQ 932
C C +G L HG EE P +G + P D S C +CVC G C
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 908
Query: 933 CISSC 937
C S+C
Sbjct: 909 CASTC 913
Score = 50.4 bits (119), Expect = 1e-05
Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)
Query: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304
SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C
Sbjct: 619 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 675
Query: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
+C + H ++ FR + + C E S E C V PC
Sbjct: 676 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 728
Query: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396
AC +DG +E EG PD P C C +P
Sbjct: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
Query: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454
G C ++ P A CP+ QV+ N + TD + S C Q
Sbjct: 789 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 841
Query: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
++ S + CA PQ G C CP +E F + S PC C C
Sbjct: 842 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 897
Query: 510 QEGHAHCQPRPC 521
Q G C PC
Sbjct: 898 QRGSFQCTLHPC 909
Score = 48.1 bits (113), Expect = 6e-05
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321
V GD S C G CPP + + +P C C +QG Y +
Sbjct: 735 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 784
Query: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375
+ + G C C+ G +SC+ + CP + S L EL E E
Sbjct: 785 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 838
Query: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
+ G + C C G+ + G P C CT+ + Y
Sbjct: 839 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 883
Query: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
G SPCH C CQ G+ C+L C T A
Sbjct: 884 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 915
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170
C C+DG C +A C GQ + N D TC + L +V +G
Sbjct: 793 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848
Query: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
P S C + G+ C + C CT G + G + +P C C C G QC
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 905
Query: 227 QRECASLC 234
CAS C
Sbjct: 906 LHPCASTC 913
Score = 44.7 bits (104), Expect = 7e-04
Identities = 93/393 (23%), Positives = 119/393 (30%), Gaps = 124/393 (31%)
Query: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
PLDP C + C C EG++ ++ ALC + C S G GE
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2375
Query: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ C +CQA + V L CP PR CL GE +
Sbjct: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2417
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPH--------DCCPQCSDCEHEGR 959
+P C C V C + C R G CCP S
Sbjct: 2418 LLLPTKDPC----CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS------- 2466
Query: 960 KYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCP 1017
C C+P C PS C Q+L G CC
Sbjct: 2467 -----------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCT 2499
Query: 1018 TCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCP 1077
+ A +C + + +CQ+ L +H+ EL CPL + C
Sbjct: 2500 SYFCACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCE 2540
Query: 1078 VCRAPTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS------ 1125
R P C G A E W+ D C SC C T+ RC S L
Sbjct: 2541 NFRCPQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHS 2597
Query: 1126 ----CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
CG K + P CL R M G
Sbjct: 2598 VENVCGCAKYECVK----APVCLSRELGVMQPG 2626
Score = 42.0 bits (97), Expect = 0.004
Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)
Query: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586
P +C DCS C + + + F P C L + VQ C+A C +
Sbjct: 2224 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2283
Query: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628
P L + C C P C + G E+ G+ C
Sbjct: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2339
Query: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683
+C +G++ +R L P A CA C S G A GE + S + C H
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2387
Query: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732
C + G S P++C P + CC LG + NQ
Sbjct: 2388 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2439
Query: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773
P R L T C CE P C L+PS CC
Sbjct: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2499
Query: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816
+ C C GE L + T C L C + RC + C
Sbjct: 2500 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2559
Query: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
P CP+ S C C P CH + + E G C
Sbjct: 2560 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2605
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925
+ +C P C R G + G+ E S D C + C +
Sbjct: 2606 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2652
Query: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976
+ + C C Q + P D C C + + F PGA
Sbjct: 2653 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2712
Query: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024
C C P G +R S + CPP + P + CC TC E
Sbjct: 2713 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2765
Query: 1025 NCSE 1028
+C +
Sbjct: 2766 SCKK 2769
Score = 39.3 bits (90), Expect = 0.029
Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)
Query: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990
++S Q R P C CS C R + F P CE+ I + + P +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2273
Query: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033
CH+ CP L + C T E C +G+LG
Sbjct: 2274 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2325
Query: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
P DP + CQ L C+ C E + L RH+ C P + + R
Sbjct: 2326 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2371
Query: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
A GE W S ++G + Q Q PD + G CP PRP SC+ F
Sbjct: 2372 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2413
Query: 1154 GD 1155
G+
Sbjct: 2414 GE 2415
Score = 37.7 bits (86), Expect = 0.084
Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)
Query: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172
AC C C AH H C ++G + P +C C P +
Sbjct: 668 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 723
Query: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215
C +L E+C G EC C ++ + + P + C
Sbjct: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 783
Query: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235
C C +G + C R A+ CP
Sbjct: 784 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 843
Query: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280
AR L G CP D CFL G+E+ G+ V S PC C C GS
Sbjct: 844 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 901
Query: 281 VQCEPLPC 288
QC PC
Sbjct: 902 FQCTLHPC 909
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725
K F E A+CH C + ++C P F G P CE+ G
Sbjct: 350 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 409
Query: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762
Y +E CN CTC G C C P CS
Sbjct: 410 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 442
Score = 36.6 bits (83), Expect = 0.19
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173
+ C C G G LP C+ G+ Y G + SP C TC C G+ QC C
Sbjct: 852 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 909
Query: 174 SELNCLESCTPPGE 187
+ +CT G+
Sbjct: 910 A-----STCTAYGD 918
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)
Query: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338
LP PP ++PG + G QC P D C H Y S F C CQ+
Sbjct: 257 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 308
Query: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386
G+V+ C CA P G RQ C+ + E + P P
Sbjct: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 368
Query: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441
+CV C DG ++ C P + CP C +H +Y G +
Sbjct: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 418
Query: 442 DSPCHACHCQDGTVTCSLVDCP 463
C+ C C G CS CP
Sbjct: 419 --DCNTCTCTSGKWECSTAVCP 438
Score = 35.4 bits (80), Expect = 0.42
Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)
Query: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233
C+ +C PP C + G + C++ C C EG I R+ ++L
Sbjct: 2309 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2354
Query: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289
C +P C D G GE S C H A ++ L CP
Sbjct: 2355 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
Query: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334
P C G++ CC VC+ +G + RL QE C
Sbjct: 2406 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2465
Query: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394
SC+ CE + L P+C D Q GR +C
Sbjct: 2466 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2497
Query: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
C + C C P P C ++ T H +N T+ P + C C++
Sbjct: 2498 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2541
Query: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503
C V C T P +CCP C P C L E+ +D E F H
Sbjct: 2542 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2596
Query: 504 CQECRCQEGHAHCQPRPCPRAP 525
E C C +AP
Sbjct: 2597 -----SVENVCGCAKYECVKAP 2613
Score = 33.5 bits (75), Expect = 1.6
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)
Query: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
+CT+ +CQ D A C +A + R C+Q G+ T CT V C+
Sbjct: 300 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 348
Query: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
+ + C+ CCP C S C++ I C
Sbjct: 349 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 380
Query: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
CP G C P C +G + G V + C+ C C +G +C C
Sbjct: 381 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 437
Query: 289 P 289
P
Sbjct: 438 P 438
Score = 33.5 bits (75), Expect = 1.6
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)
Query: 1426 FDECGPPCPRTCFNQHIPLGELAAHC-----VRPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
+D C PC +TC + AA C V CVP C P L E C+ E C +
Sbjct: 1340 YDACASPCFQTCRDPR------AASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393
Query: 1481 -VLLTGDQPLGARPSPSREPQETP 1503
+ + LG P + TP
Sbjct: 1394 PAVWVPTEALGNETLPPSQGLPTP 1417
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801
C C G + E GC P CP C +HG G + + C+
Sbjct: 382 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 422
Query: 802 CTCQEGSMRCQKKPCP 817
CTC G C CP
Sbjct: 423 CTCTSGKWECSTAVCP 438
Score = 32.7 bits (73), Expect = 2.7
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)
Query: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442
CT+ +CQ D C A+ C +P CT H + A N A
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495
P +CH C D + C VD CP + G CP C ++ G
Sbjct: 361 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 413
Query: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
S ++ C C C G C CP A C+
Sbjct: 414 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 442
Score = 32.7 bits (73), Expect = 2.7
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622
+C+A C P C P + E C C P GC P PPG
Sbjct: 356 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 413
Query: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648
+ C C C G C C PA C+
Sbjct: 414 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
Score = 32.0 bits (71), Expect = 4.6
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906
PA C +++CV CP + E G C CP C HG +P G
Sbjct: 362 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 413
Query: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938
S V D C++C C G C+ C + C+
Sbjct: 414 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 442
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 160 bits (405), Expect = 9e-39
Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)
Query: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902
F P E CR C+ GQ C L C+ L V R R C E
Sbjct: 654 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 709
Query: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949
E S V P D A +G +R +C+ CA P D C P
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
QCS C +G Y PG+S P C C+ +G S C R
Sbjct: 770 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 805
Query: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
P CP + NCS+ EL+ C Q L L + P LS
Sbjct: 806 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 852
Query: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120
G CP C P + C +G+E G++ + C +C C G+ +C
Sbjct: 853 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 908
Query: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180
C+ ++C A+GD HYRTFDG F G+C L K
Sbjct: 909 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
Query: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240
FSV V N + SG+ + +++ +G+ + D G+P FL +
Sbjct: 944 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 998
Query: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE
Sbjct: 999 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1058
Query: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356
L L + FG+SW E +DP RE A C +L S F
Sbjct: 1059 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1109
Query: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416
CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC
Sbjct: 1110 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1168
Query: 1417 GC 1418
C
Sbjct: 1169 DC 1170
Score = 159 bits (403), Expect = 1e-38
Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)
Query: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102
C +C P SC SE G CP C AP + C G G D
Sbjct: 360 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 419
Query: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
C +C+C +G C + C PA C GD H+ TFD
Sbjct: 420 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 453
Query: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218
GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q
Sbjct: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 513
Query: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276
G V + D + + P+ + L + + G++VL+D + ++ + V +
Sbjct: 514 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332
T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 630
Query: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
+AA Y + C VL F+ C A + P P+F C D C CG CLC L
Sbjct: 631 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 680
Query: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445
YA CR+ G+ +R C + C E + C PC RTC + P
Sbjct: 681 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 738
Query: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496
+L+ CV GC CP L C+P C D P G PS
Sbjct: 739 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789
Score = 158 bits (400), Expect = 3e-38
Identities = 114/344 (33%), Positives = 152/344 (44%), Gaps = 26/344 (7%)
Query: 1146 RPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA--KDCHSGDFSVHVTNDDR-GRSGVAWT 1202
R + C A+G H TFDG + G SY L + FS+ V ND + G S +
Sbjct: 75 RDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
Query: 1203 QEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD 1261
+ V++ +G+ + L ++ VT G V LP + +L G+ ++ H Q + WD
Sbjct: 135 RAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRH-QSAFTLAWD 191
Query: 1262 GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR 1321
G S V + + G T GLCGN N +DDL G L F +SWQ P
Sbjct: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
Query: 1322 PCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPG 1381
P ++ PC + +C L PF CHA V P PF A+C DLC
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ---- 307
Query: 1382 SSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCF 1438
S D A C AL YA C QAG WR C V C E+ F ++EC CP +C
Sbjct: 308 SMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK-EKAFTYNECIACCPASCH 366
Query: 1439 NQHIPLGELAAHCVR---PCVPGCQCPAGLVEHEAHCIPPEACP 1479
+ A CV CV GC CP GL+ + C+ P CP
Sbjct: 367 PR--------ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
Score = 84.3 bits (207), Expect = 8e-16
Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)
Query: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154
C C+ G +R QSQ C +P CG A + CCP C R C F
Sbjct: 1987 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2043
Query: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211
D + TFDG + Y+L++ +VHV + G + W V+L
Sbjct: 2044 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2102
Query: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265
+A ++ D VTVD PV P + +E GH ++ +Q+ W G
Sbjct: 2103 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
Query: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322
VE S QG GLCG +G A +DL +G ++ A F +SWQV L
Sbjct: 2162 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2214
Query: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379
S G+ D C A + + ++ + FS CH VPPE F + D
Sbjct: 2215 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2263
Query: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437
+ C AL Y + C + V WR C C + + C C P+TC
Sbjct: 2264 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2319
Query: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
Q LG L + GC C G + H H CIP C
Sbjct: 2320 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
Score = 58.5 bits (140), Expect = 5e-08
Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)
Query: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
C C D E VDG D C EG A CP C P
Sbjct: 720 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 767
Query: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
+ C F G +YP G +D P C C G + C +R P C
Sbjct: 768 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 811
Query: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651
P C H + C + L L+ SVS R PC CA P R
Sbjct: 812 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 862
Query: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700
G C P C ++GKE+ G++ SP CH C+C GS C CA
Sbjct: 863 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 910
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
PC P G C +P C G GD R C++G C
Sbjct: 715 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 752
Query: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
PP + C P C +QG ++ G+ CH C +G +SC+ +A A
Sbjct: 753 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 809
Query: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758
A CP G+ +++ + E TC L R PC
Sbjct: 810 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
Query: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814
GC+ P L+ G C P C + G G+ + P C C CQ GS +C
Sbjct: 853 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 907
Query: 815 PC 816
PC
Sbjct: 908 PC 909
Score = 50.8 bits (120), Expect = 1e-05
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372
C A +E PC A R ++ + CGV SR V PP+ + CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
+ C+C PG S D HC+ ++ R P CP G
Sbjct: 767 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 815
Query: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
VF C RTC Q L L+ PC+ GC CP GL+ H C PE
Sbjct: 816 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 872
Query: 1478 CP 1479
CP
Sbjct: 873 CP 874
Score = 50.8 bits (120), Expect = 1e-05
Identities = 52/185 (28%), Positives = 64/185 (34%), Gaps = 54/185 (29%)
Query: 771 CCPTCQ-GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPC 829
C P Q C + GV G D P+ C C++G M C + P A CP G
Sbjct: 765 CVPRNQCSCHFQGVDYPPG----DSDIPSLGHCHCKDGVMSCDSR-APAAACP---AGQV 816
Query: 830 F--CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERG 887
F C H+ L RE C L V+ RG
Sbjct: 817 FVNCSDLHTDLELSRERT----------------------------CEQQLLNLSVSARG 848
Query: 888 SCCPRC---RGCLAHG------EEHP---EGSRWVPPD---SACSSCVCHEGVVTCARIQ 932
C C +G L HG EE P +G + P D S C +CVC G C
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 908
Query: 933 CISSC 937
C S+C
Sbjct: 909 CASTC 913
Score = 50.4 bits (119), Expect = 1e-05
Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)
Query: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304
SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C
Sbjct: 619 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 675
Query: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
+C + H ++ FR + + C E S E C V PC
Sbjct: 676 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 728
Query: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396
AC +DG +E EG PD P C C +P
Sbjct: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
Query: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454
G C ++ P A CP+ QV+ N + TD + S C Q
Sbjct: 789 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 841
Query: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
++ S + CA PQ G C CP +E F + S PC C C
Sbjct: 842 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 897
Query: 510 QEGHAHCQPRPC 521
Q G C PC
Sbjct: 898 QRGSFQCTLHPC 909
Score = 48.1 bits (113), Expect = 6e-05
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321
V GD S C G CPP + + +P C C +QG Y +
Sbjct: 735 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 784
Query: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375
+ + G C C+ G +SC+ + CP + S L EL E E
Sbjct: 785 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 838
Query: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
+ G + C C G+ + G P C CT+ + Y
Sbjct: 839 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 883
Query: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
G SPCH C CQ G+ C+L C T A
Sbjct: 884 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 915
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170
C C+DG C +A C GQ + N D TC + L +V +G
Sbjct: 793 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848
Query: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
P S C + G+ C + C CT G + G + +P C C C G QC
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 905
Query: 227 QRECASLC 234
CAS C
Sbjct: 906 LHPCASTC 913
Score = 44.7 bits (104), Expect = 7e-04
Identities = 93/393 (23%), Positives = 119/393 (30%), Gaps = 124/393 (31%)
Query: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
PLDP C + C C EG++ ++ ALC + C S G GE
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2375
Query: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
+ C +CQA + V L CP PR CL GE +
Sbjct: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2417
Query: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPH--------DCCPQCSDCEHEGR 959
+P C C V C + C R G CCP S
Sbjct: 2418 LLLPTKDPC----CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS------- 2466
Query: 960 KYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCP 1017
C C+P C PS C Q+L G CC
Sbjct: 2467 -----------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCT 2499
Query: 1018 TCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCP 1077
+ A +C + + +CQ+ L +H+ EL CPL + C
Sbjct: 2500 SYFCACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCE 2540
Query: 1078 VCRAPTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS------ 1125
R P C G A E W+ D C SC C T+ RC S L
Sbjct: 2541 NFRCPQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHS 2597
Query: 1126 ----CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
CG K + P CL R M G
Sbjct: 2598 VENVCGCAKYECVK----APVCLSRELGVMQPG 2626
Score = 42.0 bits (97), Expect = 0.004
Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)
Query: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586
P +C DCS C + + + F P C L + VQ C+A C +
Sbjct: 2224 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2283
Query: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628
P L + C C P C + G E+ G+ C
Sbjct: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2339
Query: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683
+C +G++ +R L P A CA C S G A GE + S + C H
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2387
Query: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732
C + G S P++C P + CC LG + NQ
Sbjct: 2388 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2439
Query: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773
P R L T C CE P C L+PS CC
Sbjct: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2499
Query: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816
+ C C GE L + T C L C + RC + C
Sbjct: 2500 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2559
Query: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
P CP+ S C C P CH + + E G C
Sbjct: 2560 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2605
Query: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925
+ +C P C R G + G+ E S D C + C +
Sbjct: 2606 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2652
Query: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976
+ + C C Q + P D C C + + F PGA
Sbjct: 2653 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2712
Query: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024
C C P G +R S + CPP + P + CC TC E
Sbjct: 2713 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2765
Query: 1025 NCSE 1028
+C +
Sbjct: 2766 SCKK 2769
Score = 39.3 bits (90), Expect = 0.029
Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)
Query: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990
++S Q R P C CS C R + F P CE+ I + + P +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2273
Query: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033
CH+ CP L + C T E C +G+LG
Sbjct: 2274 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2325
Query: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
P DP + CQ L C+ C E + L RH+ C P + + R
Sbjct: 2326 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2371
Query: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
A GE W S ++G + Q Q PD + G CP PRP SC+ F
Sbjct: 2372 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2413
Query: 1154 GD 1155
G+
Sbjct: 2414 GE 2415
Score = 37.7 bits (86), Expect = 0.084
Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)
Query: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172
AC C C AH H C ++G + P +C C P +
Sbjct: 668 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 723
Query: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215
C +L E+C G EC C ++ + + P + C
Sbjct: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 783
Query: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235
C C +G + C R A+ CP
Sbjct: 784 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 843
Query: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280
AR L G CP D CFL G+E+ G+ V S PC C C GS
Sbjct: 844 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 901
Query: 281 VQCEPLPC 288
QC PC
Sbjct: 902 FQCTLHPC 909
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725
K F E A+CH C + ++C P F G P CE+ G
Sbjct: 350 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 409
Query: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762
Y +E CN CTC G C C P CS
Sbjct: 410 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 442
Score = 36.6 bits (83), Expect = 0.19
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173
+ C C G G LP C+ G+ Y G + SP C TC C G+ QC C
Sbjct: 852 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 909
Query: 174 SELNCLESCTPPGE 187
+ +CT G+
Sbjct: 910 A-----STCTAYGD 918
Score = 36.2 bits (82), Expect = 0.25
Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)
Query: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338
LP PP ++PG + G QC P D C H Y S F C CQ+
Sbjct: 257 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 308
Query: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386
G+V+ C CA P G RQ C+ + E + P P
Sbjct: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 368
Query: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441
+CV C DG ++ C P + CP C +H +Y G +
Sbjct: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 418
Query: 442 DSPCHACHCQDGTVTCSLVDCP 463
C+ C C G CS CP
Sbjct: 419 --DCNTCTCTSGKWECSTAVCP 438
Score = 35.4 bits (80), Expect = 0.42
Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)
Query: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233
C+ +C PP C + G + C++ C C EG I R+ ++L
Sbjct: 2309 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2354
Query: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289
C +P C D G GE S C H A ++ L CP
Sbjct: 2355 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
Query: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334
P C G++ CC VC+ +G + RL QE C
Sbjct: 2406 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2465
Query: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394
SC+ CE + L P+C D Q GR +C
Sbjct: 2466 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2497
Query: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
C + C C P P C ++ T H +N T+ P + C C++
Sbjct: 2498 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2541
Query: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503
C V C T P +CCP C P C L E+ +D E F H
Sbjct: 2542 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2596
Query: 504 CQECRCQEGHAHCQPRPCPRAP 525
E C C +AP
Sbjct: 2597 -----SVENVCGCAKYECVKAP 2613
Score = 33.5 bits (75), Expect = 1.6
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)
Query: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
+CT+ +CQ D A C +A + R C+Q G+ T CT V C+
Sbjct: 300 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 348
Query: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
+ + C+ CCP C S C++ I C
Sbjct: 349 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 380
Query: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
CP G C P C +G + G V + C+ C C +G +C C
Sbjct: 381 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 437
Query: 289 P 289
P
Sbjct: 438 P 438
Score = 33.5 bits (75), Expect = 1.6
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)
Query: 1426 FDECGPPCPRTCFNQHIPLGELAAHC-----VRPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
+D C PC +TC + AA C V CVP C P L E C+ E C +
Sbjct: 1340 YDACASPCFQTCRDPR------AASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393
Query: 1481 -VLLTGDQPLGARPSPSREPQETP 1503
+ + LG P + TP
Sbjct: 1394 PAVWVPTEALGNETLPPSQGLPTP 1417
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801
C C G + E GC P CP C +HG G + + C+
Sbjct: 382 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 422
Query: 802 CTCQEGSMRCQKKPCP 817
CTC G C CP
Sbjct: 423 CTCTSGKWECSTAVCP 438
Score = 32.7 bits (73), Expect = 2.7
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)
Query: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442
CT+ +CQ D C A+ C +P CT H + A N A
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495
P +CH C D + C VD CP + G CP C ++ G
Sbjct: 361 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 413
Query: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
S ++ C C C G C CP A C+
Sbjct: 414 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 442
Score = 32.7 bits (73), Expect = 2.7
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622
+C+A C P C P + E C C P GC P PPG
Sbjct: 356 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 413
Query: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648
+ C C C G C C PA C+
Sbjct: 414 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
Score = 32.0 bits (71), Expect = 4.6
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906
PA C +++CV CP + E G C CP C HG +P G
Sbjct: 362 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 413
Query: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938
S V D C++C C G C+ C + C+
Sbjct: 414 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 442
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 150 bits (379), Expect = 9e-36
Identities = 127/479 (26%), Positives = 193/479 (40%), Gaps = 70/479 (14%)
Query: 1023 LSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTP--PGSCCP--- 1077
L NCS G + + P + Q T ++ C + P+ + + P G CP
Sbjct: 1214 LQNCSGGAEYVDCSDP------KAQRRT----NRTCSTRNIPVFDENLPCKRGCFCPEGM 1263
Query: 1078 ------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDK 1130
+C P C GRE G +V C C+C+ G+ C C +
Sbjct: 1264 VRNSKGICVFPNDCPCSFGGREYDEGSVTSVG-CNECTCIKGSWSCTQNECQTI------ 1316
Query: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC---HSGDFSV 1187
C +G+ H RTFDG+ F G C Y +D +G F +
Sbjct: 1317 -------------------CHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRI 1357
Query: 1188 HVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVT-VDGHPVALPFLQEPLLYVELRGH 1246
+ G+ ++++ V D + +LQDG VT V L + G
Sbjct: 1358 LTESVPCCEDGLTCSRKIIVAFQDQNI-VLQDGKVTAVKSTESKKCELNANAYSIHTVGL 1416
Query: 1247 TVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAA 1306
+IL Q G+ V+WD +++ V + ++ G+ CGLCGN NG +DD +
Sbjct: 1417 YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1476
Query: 1307 FGNSWQVSEGLWPGRPCS-AGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPE 1365
FGNSW+ S+ CS + PC + Y + A +C +L+ S F CH V P
Sbjct: 1477 FGNSWKTSQ------ECSDTVAQTFPCDSNPY-CKAWAVRKCEILRDSTFRDCHNKVDPS 1529
Query: 1366 PFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGC-----PL 1420
+ C+ + CAC C A+ YA C GV +WR P LC V C P
Sbjct: 1530 AYHDVCIEEACACDM-EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPG 1588
Query: 1421 ERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAG-LVEHEAHCIPPEAC 1478
E + ++ CG +TC +Q + G+ + + C C A L E+ C+ C
Sbjct: 1589 ECRWHYEPCGTVTAKTCKDQLV--GQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSEC 1645
Score = 100 bits (250), Expect = 8e-21
Identities = 109/450 (24%), Positives = 166/450 (36%), Gaps = 53/450 (11%)
Query: 1052 LCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVH-----QGREVAS-GERWTVDTCT 1105
+C Q CPE + P +C V CV +G + GE+
Sbjct: 756 VCETQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKA 815
Query: 1106 SCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRL 1165
C C + Q CG + SC P C G TFDG
Sbjct: 816 ECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCP--GRCKVEGSS-LTTFDGVK 872
Query: 1166 LHFQGSCSYVLAKDCHSGDFSVHVTNDD--RGRSGVAWTQEVAVLLGDMAVRLL---QDG 1220
+F G+C ++ H+ D+S+ V G++G +L + V DG
Sbjct: 873 YNFPGNCHFLAV---HNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDG 929
Query: 1221 AVTVDG-------HPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGS 1273
VT D + + Y+++ + H + +Q++ Q+ VS+P +
Sbjct: 930 TVTNDKIRNQGYYYSDKIQIFNASSSYLQVETY---FHVKLQIQIV--PVMQLYVSMPPN 984
Query: 1274 YQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCR 1333
T GLCG++N A+DD + +L + AF NSW++ C G +P
Sbjct: 985 QFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-------CPKG---NPSS 1034
Query: 1334 AAGYRARREANARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDA 1391
+ A CG+L S P + CH +V P+P+ C C C ++ CLC
Sbjct: 1035 CISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC---ENSQDCLCTI 1091
Query: 1392 LEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
L Y C + LC CP G VF C +C + L E C
Sbjct: 1092 LGNYVKACAEKETYIVGWRTGLCEHSCP--SGLVFKYNVKACNSSCRS----LSERDRSC 1145
Query: 1452 VRPCVP--GCQCPAGLVE-HEAHCIPPEAC 1478
VP GC CP + + +E +C+ C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 1175
Score = 43.1 bits (100), Expect = 0.002
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 55/224 (24%)
Query: 437 NFTDADSPCHACHCQDGTVTCSLVDCPPTTCARP----QSGPGQCCPRCP-DCILEEEVF 491
N +S C + +D + C + D P C P Q+ G C + DC + +EV
Sbjct: 1127 NVKACNSSCRSLSERDRS--CDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVM 1184
Query: 492 VDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPS 551
G+ H D +C C++G CQ +P +CSG
Sbjct: 1185 QPGKLI-HIDD--NKCVCRDGILLCQ------------IPIDLTLQNCSG---------- 1219
Query: 552 GADFPHPSDPCRLCR----CLSGNVQCLARRCVPLPCPEPVLLPGECCPQ---------C 598
GA++ SDP R C + N+ LPC G CP+ C
Sbjct: 1220 GAEYVDCSDPKAQRRTNRTCSTRNIPVFDEN---LPCKR-----GCFCPEGMVRNSKGIC 1271
Query: 599 PAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
P CP + R + S C C C+ GS SC + C
Sbjct: 1272 VFPNDCPC--SFGGREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313
Score = 40.8 bits (94), Expect = 0.010
Identities = 32/111 (28%), Positives = 41/111 (36%), Gaps = 27/111 (24%)
Query: 796 DPTCSLCTCQEGSMRCQKKPCPPALCPHPSP-------GPCFCPVCH------------- 835
D C C E + + P PA C + +P C CP +
Sbjct: 754 DVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVL 813
Query: 836 ----SCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQ 882
C S G +Q GE EGP GS C CQ + SC CP CK++
Sbjct: 814 KAECPCESSGTVYQPGEVREGPCGS--QCTCQDAKWSCTEALCPG-RCKVE 861
Score = 40.0 bits (92), Expect = 0.017
Identities = 35/129 (27%), Positives = 48/129 (37%), Gaps = 19/129 (14%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQ--------- 167
CVC+DG C L + CS G Y + T C T +
Sbjct: 1197 CVCRDGILLCQIPIDLT-LQNCS-GGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCK 1254
Query: 168 --CQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQC 225
C P N C P +C C+ GG ++ G T+ G C C C++G C
Sbjct: 1255 RGCFCPEGMVRNSKGICVFPNDCP---CSFGGREYDEGSV-TSVG--CNECTCIKGSWSC 1308
Query: 226 RQRECASLC 234
Q EC ++C
Sbjct: 1309 TQNECQTIC 1317
Score = 36.6 bits (83), Expect = 0.19
Identities = 47/185 (25%), Positives = 63/185 (34%), Gaps = 46/185 (24%)
Query: 168 CQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDP-CRICRCLEGHIQCR 226
C C + +C E +C ++G +E W + D C RC E HI
Sbjct: 714 CIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFE---SWRSDSDVVCETQRCPEQHIY-- 768
Query: 227 QRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPL 286
+EC P+ P TC V P + S C C G + +
Sbjct: 769 -KECG-----PSNP--ATCSNVA--------------PFQDSECVSGCTCPEGYLLDD-- 804
Query: 287 PCPPVPCRHPGKIPGQC-CPVCDGCEYQGHQYQSQETFRLQERGLC-VRCSCQAGEVSCE 344
GK + CP CE G YQ E G C +C+CQ + SC
Sbjct: 805 ------IGEKGKCVLKAECP----CESSGTVYQPGEV----REGPCGSQCTCQDAKWSCT 850
Query: 345 EQECP 349
E CP
Sbjct: 851 EALCP 855
Score = 36.2 bits (82), Expect = 0.25
Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDC--HSGDFSVHV-TNDDR 1194
Y++F+GR+ F+ SC Y + C GDF++ + N+DR
Sbjct: 616 YKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNNDR 655
Score = 33.9 bits (76), Expect = 1.2
Identities = 46/168 (27%), Positives = 57/168 (33%), Gaps = 38/168 (22%)
Query: 334 CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPC-TACVCQ 392
C+C G + + E C L A CP CE G + G E PC + C CQ
Sbjct: 794 CTCPEGYLLDDIGE--KGKCVLKAE----CP-CESSGTVYQPG---EVREGPCGSQCTCQ 843
Query: 393 DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH--ACHC 450
D C LC PG C S T V N CH A H
Sbjct: 844 DAKWSCTEALC-----------PGRCKVEGSSLTTFDGVKYN------FPGNCHFLAVHN 886
Query: 451 QDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFS 498
+D +++ L CP SG C +L V VD F+
Sbjct: 887 EDWSISVELRPCP--------SGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Score = 32.3 bits (72), Expect = 3.5
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 16/73 (21%)
Query: 802 CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCR 861
C C EG +R K +C P+ CP C GRE+ +G + C C
Sbjct: 1257 CFCPEGMVRNSK-----GICVFPND----CP----CSFGGREYDEGSV---TSVGCNECT 1300
Query: 862 CQAGQVSCVRLQC 874
C G SC + +C
Sbjct: 1301 CIKGSWSCTQNEC 1313
Score = 31.2 bits (69), Expect = 7.9
Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 995 QCPSLVGCPPSQLLPP-GPQHCCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWL 1052
+C S CP LL G + C AE S + PC + C CQD W
Sbjct: 789 ECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWS 848
Query: 1053 CIHQACP 1059
C CP
Sbjct: 849 CTEALCP 855
Score = 31.2 bits (69), Expect = 7.9
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 15/73 (20%)
Query: 685 CLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC 744
C C EG V + +C FP + CP C + G Y E CN CTC
Sbjct: 1257 CFCPEGMVRN-----SKGICVFP---NDCP----CSFGGREY---DEGSVTSVGCNECTC 1301
Query: 745 LGGFVTCGRRPCE 757
+ G +C + C+
Sbjct: 1302 IKGSWSCTQNECQ 1314
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 150 bits (379), Expect = 9e-36
Identities = 127/479 (26%), Positives = 193/479 (40%), Gaps = 70/479 (14%)
Query: 1023 LSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTP--PGSCCP--- 1077
L NCS G + + P + Q T ++ C + P+ + + P G CP
Sbjct: 1214 LQNCSGGAEYVDCSDP------KAQRRT----NRTCSTRNIPVFDENLPCKRGCFCPEGM 1263
Query: 1078 ------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDK 1130
+C P C GRE G +V C C+C+ G+ C C +
Sbjct: 1264 VRNSKGICVFPNDCPCSFGGREYDEGSVTSVG-CNECTCIKGSWSCTQNECQTI------ 1316
Query: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC---HSGDFSV 1187
C +G+ H RTFDG+ F G C Y +D +G F +
Sbjct: 1317 -------------------CHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRI 1357
Query: 1188 HVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVT-VDGHPVALPFLQEPLLYVELRGH 1246
+ G+ ++++ V D + +LQDG VT V L + G
Sbjct: 1358 LTESVPCCEDGLTCSRKIIVAFQDQNI-VLQDGKVTAVKSTESKKCELNANAYSIHTVGL 1416
Query: 1247 TVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAA 1306
+IL Q G+ V+WD +++ V + ++ G+ CGLCGN NG +DD +
Sbjct: 1417 YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1476
Query: 1307 FGNSWQVSEGLWPGRPCS-AGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPE 1365
FGNSW+ S+ CS + PC + Y + A +C +L+ S F CH V P
Sbjct: 1477 FGNSWKTSQ------ECSDTVAQTFPCDSNPY-CKAWAVRKCEILRDSTFRDCHNKVDPS 1529
Query: 1366 PFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGC-----PL 1420
+ C+ + CAC C A+ YA C GV +WR P LC V C P
Sbjct: 1530 AYHDVCIEEACACDM-EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPG 1588
Query: 1421 ERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAG-LVEHEAHCIPPEAC 1478
E + ++ CG +TC +Q + G+ + + C C A L E+ C+ C
Sbjct: 1589 ECRWHYEPCGTVTAKTCKDQLV--GQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSEC 1645
Score = 100 bits (249), Expect = 1e-20
Identities = 109/450 (24%), Positives = 166/450 (36%), Gaps = 53/450 (11%)
Query: 1052 LCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVH-----QGREVAS-GERWTVDTCT 1105
+C Q CPE + P +C V CV +G + GE+
Sbjct: 756 VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKA 815
Query: 1106 SCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRL 1165
C C + Q CG + SC P C G TFDG
Sbjct: 816 ECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCP--GRCKVEGSS-LTTFDGVK 872
Query: 1166 LHFQGSCSYVLAKDCHSGDFSVHVTNDD--RGRSGVAWTQEVAVLLGDMAVRLL---QDG 1220
+F G+C ++ H+ D+S+ V G++G +L + V DG
Sbjct: 873 YNFPGNCHFLAV---HNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDG 929
Query: 1221 AVTVDG-------HPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGS 1273
VT D + + Y+++ + H + +Q++ Q+ VS+P +
Sbjct: 930 TVTNDKIRNQGYYYSDKIQIFNASSSYLQVETY---FHVKLQIQIV--PVMQLYVSMPPN 984
Query: 1274 YQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCR 1333
T GLCG++N A+DD + +L + AF NSW++ C G +P
Sbjct: 985 QFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-------CPKG---NPSS 1034
Query: 1334 AAGYRARREANARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDA 1391
+ A CG+L S P + CH +V P+P+ C C C ++ CLC
Sbjct: 1035 CISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC---ENSQDCLCTI 1091
Query: 1392 LEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
L Y C + LC CP G VF C +C + L E C
Sbjct: 1092 LGNYVKACAEKETYIVGWRTGLCEHSCP--SGLVFKYNVKACNSSCRS----LSERDRSC 1145
Query: 1452 VRPCVP--GCQCPAGLVE-HEAHCIPPEAC 1478
VP GC CP + + +E +C+ C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 1175
Score = 43.1 bits (100), Expect = 0.002
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 55/224 (24%)
Query: 437 NFTDADSPCHACHCQDGTVTCSLVDCPPTTCARP----QSGPGQCCPRCP-DCILEEEVF 491
N +S C + +D + C + D P C P Q+ G C + DC + +EV
Sbjct: 1127 NVKACNSSCRSLSERDRS--CDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVM 1184
Query: 492 VDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPS 551
G+ H D +C C++G CQ +P +CSG
Sbjct: 1185 QPGKLI-HIDD--NKCVCRDGILLCQ------------IPIDLTLQNCSG---------- 1219
Query: 552 GADFPHPSDPCRLCR----CLSGNVQCLARRCVPLPCPEPVLLPGECCPQ---------C 598
GA++ SDP R C + N+ LPC G CP+ C
Sbjct: 1220 GAEYVDCSDPKAQRRTNRTCSTRNIPVFDEN---LPCKR-----GCFCPEGMVRNSKGIC 1271
Query: 599 PAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
P CP + R + S C C C+ GS SC + C
Sbjct: 1272 VFPNDCPC--SFGGREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313
Score = 40.8 bits (94), Expect = 0.010
Identities = 32/111 (28%), Positives = 41/111 (36%), Gaps = 27/111 (24%)
Query: 796 DPTCSLCTCQEGSMRCQKKPCPPALCPHPSP-------GPCFCPVCH------------- 835
D C C E + + P PA C + +P C CP +
Sbjct: 754 DVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVL 813
Query: 836 ----SCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQ 882
C S G +Q GE EGP GS C CQ + SC CP CK++
Sbjct: 814 KAECPCESSGTVYQPGEVREGPCGS--QCTCQDAKWSCTEALCPG-RCKVE 861
Score = 40.0 bits (92), Expect = 0.017
Identities = 35/129 (27%), Positives = 48/129 (37%), Gaps = 19/129 (14%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQ--------- 167
CVC+DG C L + CS G Y + T C T +
Sbjct: 1197 CVCRDGILLCQIPIDLT-LQNCS-GGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCK 1254
Query: 168 --CQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQC 225
C P N C P +C C+ GG ++ G T+ G C C C++G C
Sbjct: 1255 RGCFCPEGMVRNSKGICVFPNDCP---CSFGGREYDEGSV-TSVG--CNECTCIKGSWSC 1308
Query: 226 RQRECASLC 234
Q EC ++C
Sbjct: 1309 TQNECQTIC 1317
Score = 36.2 bits (82), Expect = 0.25
Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDC--HSGDFSVHV-TNDDR 1194
Y++F+GR+ F+ SC Y + C GDF++ + N+DR
Sbjct: 616 YKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNNDR 655
Score = 35.8 bits (81), Expect = 0.32
Identities = 47/185 (25%), Positives = 63/185 (34%), Gaps = 46/185 (24%)
Query: 168 CQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDP-CRICRCLEGHIQCR 226
C C + +C E +C ++G +E W + D C RC E HI
Sbjct: 714 CIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFE---SWRSDSDVVCGTQRCPEQHIY-- 768
Query: 227 QRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPL 286
+EC P+ P TC V P + S C C G + +
Sbjct: 769 -KECG-----PSNP--ATCSNVA--------------PFQDSECVSGCTCPEGYLLDD-- 804
Query: 287 PCPPVPCRHPGKIPGQC-CPVCDGCEYQGHQYQSQETFRLQERGLC-VRCSCQAGEVSCE 344
GK + CP CE G YQ E G C +C+CQ + SC
Sbjct: 805 ------IGEKGKCVLKAECP----CESSGTVYQPGEV----REGPCGSQCTCQDAKWSCT 850
Query: 345 EQECP 349
E CP
Sbjct: 851 EALCP 855
Score = 33.9 bits (76), Expect = 1.2
Identities = 46/168 (27%), Positives = 57/168 (33%), Gaps = 38/168 (22%)
Query: 334 CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPC-TACVCQ 392
C+C G + + E C L A CP CE G + G E PC + C CQ
Sbjct: 794 CTCPEGYLLDDIGE--KGKCVLKAE----CP-CESSGTVYQPG---EVREGPCGSQCTCQ 843
Query: 393 DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH--ACHC 450
D C LC PG C S T V N CH A H
Sbjct: 844 DAKWSCTEALC-----------PGRCKVEGSSLTTFDGVKYN------FPGNCHFLAVHN 886
Query: 451 QDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFS 498
+D +++ L CP SG C +L V VD F+
Sbjct: 887 EDWSISVELRPCP--------SGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Score = 32.3 bits (72), Expect = 3.5
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 16/73 (21%)
Query: 802 CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCR 861
C C EG +R K +C P+ CP C GRE+ +G + C C
Sbjct: 1257 CFCPEGMVRNSK-----GICVFPND----CP----CSFGGREYDEGSV---TSVGCNECT 1300
Query: 862 CQAGQVSCVRLQC 874
C G SC + +C
Sbjct: 1301 CIKGSWSCTQNEC 1313
Score = 31.2 bits (69), Expect = 7.9
Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 995 QCPSLVGCPPSQLLPP-GPQHCCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWL 1052
+C S CP LL G + C AE S + PC + C CQD W
Sbjct: 789 ECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWS 848
Query: 1053 CIHQACP 1059
C CP
Sbjct: 849 CTEALCP 855
Score = 31.2 bits (69), Expect = 7.9
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 15/73 (20%)
Query: 685 CLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC 744
C C EG V + +C FP + CP C + G Y E CN CTC
Sbjct: 1257 CFCPEGMVRN-----SKGICVFP---NDCP----CSFGGREY---DEGSVTSVGCNECTC 1301
Query: 745 LGGFVTCGRRPCE 757
+ G +C + C+
Sbjct: 1302 IKGSWSCTQNECQ 1314
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 144 bits (364), Expect = 5e-34
Identities = 124/478 (25%), Positives = 188/478 (39%), Gaps = 93/478 (19%)
Query: 1015 CCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGS 1074
CCP C LGS L D CY CP+ G+
Sbjct: 343 CCPPTCTFEKQC----LGSNLHCLDGCY---------------CPDGLV------MDNGT 377
Query: 1075 CCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPAL 1134
C + P C G + G + + CT C C+ G C Q C
Sbjct: 378 CISLENCP---CGFHGLAYSVGSKIEQE-CTECVCVGGVWNCTEQDC------------- 420
Query: 1135 SPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDR 1194
P C GD H+ TFDGR F G C Y+L K F++ +
Sbjct: 421 ------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPC 468
Query: 1195 GRS-GVAWTQEVAVLLGD---MAVRLLQDGAVTVDGHPVALPFLQEPLLYVE-LRGHTVI 1249
++ G+ Q + ++L D V L + G + + F ++ ++ L ++
Sbjct: 469 EQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQ---GFNLNGIVEIQTLSSLFIL 525
Query: 1250 LHAQPGLQVLW--DGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAF 1307
L GL++L+ DG+ ++ + + +++ RT GLCG FNG +DD P G++ +
Sbjct: 526 LKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLH 584
Query: 1308 GNSWQVSEGLWPGRPCSAGREVDPC----RAAGYRARREANARCGVLKSSPFSRCHAVVP 1363
N+W+VS + VDPC + GY A C V+ F+ CH +
Sbjct: 585 ANAWRVSSTCFAPVHVPV---VDPCNINQQNIGYA------AHCDVIHQELFAPCHIYIS 635
Query: 1364 PEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGP-TLCVVGCPLER 1422
P ++ C +D C CG +CLC+AL YA C Q GV +R + C V C ++
Sbjct: 636 PGLYYQLCRHDACKCG-----SSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC--QK 688
Query: 1423 GFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEA--HCIPPEAC 1478
G ++ C C +C + P C C GC CP G + C+P C
Sbjct: 689 GMLYHHCSSFCLHSCISLSSP-----EQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHC 741
Score = 137 bits (345), Expect = 8e-32
Identities = 99/341 (29%), Positives = 147/341 (43%), Gaps = 22/341 (6%)
Query: 1146 RPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGV-A 1200
R C +G H+ TFDG +F G+CSY+ AKDC GD ++V V N + V +
Sbjct: 60 RDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDC--GDLEPRYTVWVHNSPKCLGSVYS 117
Query: 1201 WTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW 1260
+ +++ + + + +G + LP + ++E +++ G + W
Sbjct: 118 CYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQI-FIEKLADYILVKTTFGFSLAW 176
Query: 1261 DGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPG 1320
DG S + + + ++G++CGLCGN+N DD + A F NSW V
Sbjct: 177 DGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTK 236
Query: 1321 RPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGP 1380
+ +PC ++G A +C +L PF CH + P + A+CV DLC
Sbjct: 237 CVLTPSDFPNPC-SSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCK--- 292
Query: 1381 GSSADACLCDALEAYASHCRQAGV-TPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCF 1438
+ D C A YA C AG WR C C + FV +C CP TC
Sbjct: 293 -TDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKC--DDSFVHRDCISCCPPTCT 349
Query: 1439 NQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACP 1479
+ LG C+ GC CP GLV CI E CP
Sbjct: 350 FEKQCLGSNL-----HCLDGCYCPDGLVMDNGTCISLENCP 385
Score = 133 bits (335), Expect = 1e-30
Identities = 116/446 (26%), Positives = 171/446 (38%), Gaps = 62/446 (13%)
Query: 1002 CPPSQLLPPGPQHCCPTCAEALSNCSEGLL-------------------GSELAP----P 1038
C S + P+ C CAE NC EG GS P P
Sbjct: 699 CLHSCISLSSPEQCSDDCAEGC-NCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIP 757
Query: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
P CQC + T C EL+ P + P G CR P G
Sbjct: 758 TPSGLCQCSNGT-----VKCDELATPSAVHICPEGKEYFDCRFPDPELPAGG-------- 804
Query: 1099 WTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSP-GSCCPRCLPRPASCMAFGDPH 1157
V+ T+C+ +A C SP G AP + G P PA C +GD H
Sbjct: 805 --VNCETTCANLAMNFTCTPS--SPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRH 860
Query: 1158 YRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLL 1217
Y +FDG + C L K D SV N + + ++ V + +GD + L
Sbjct: 861 YYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 1218 QDGAVTVDGHPVALPFLQEPLLYVELRG--HTVILHAQPGLQVLWDGQSQVEVSVPGSYQ 1275
T + FL+ Y + + V+ + + +LWD ++ + + V ++
Sbjct: 921 D----TPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWK 976
Query: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPG---RPCSAGREVDPC 1332
+ GLCGNF+ +D+ L + + FG+SW + + P +PC A + P
Sbjct: 977 NKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFP- 1035
Query: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
A C +L S F+ C V+ F C D C C G + CLC ++
Sbjct: 1036 ---------YAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCE-CLCTSI 1085
Query: 1393 EAYASHCRQAGVTPTWRGPTLCVVGC 1418
AYA C Q G++ WR T+C + C
Sbjct: 1086 AAYAYKCCQEGISIHWRSSTVCSLDC 1111
Score = 78.2 bits (191), Expect = 6e-14
Identities = 92/357 (25%), Positives = 128/357 (35%), Gaps = 43/357 (12%)
Query: 1139 CCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKD------CHSGDFSVHVTND 1192
CCP P C + TFDG SY+L + H S++
Sbjct: 1431 CCPEW-ECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPS 1489
Query: 1193 DRGRSGVAWTQ-EVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILH 1251
R SG+ + + V + + V L V VD V LPF + L +E G ++
Sbjct: 1490 GR-ISGLCFKKLNVTTPIHKIIVNRLAR-KVEVDSIVVPLPFSSQELS-IEDSGSMYVIT 1546
Query: 1252 AQPGLQVLWD---GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFG 1308
GL + W G + + T GLCG N DDL+ G ++ + G
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606
Query: 1309 ---NSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPE 1365
SW++ + EV R + + +L F CH V PE
Sbjct: 1607 LFIESWEIEKSF----------EVTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPE 1656
Query: 1366 PFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFV 1425
F + CDAL AY + C + + WR P C + CP G
Sbjct: 1657 DFCEKMWINYTYFWNYE------CDALSAYVALCNKFDICIQWRTPDYCSLSCP--EGKE 1708
Query: 1426 FDECGPPC-PRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
+ C PC RTC NQ G + +R C C G V H H CIP + C
Sbjct: 1709 YQPCVRPCEARTCLNQWF-YGHTSCLNLR---EDCVCKVGTVLHRPHSAQCIPEKEC 1761
Score = 45.1 bits (105), Expect = 5e-04
Identities = 42/160 (26%), Positives = 55/160 (34%), Gaps = 49/160 (30%)
Query: 662 CLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEY 721
C Y+G + GE P+P+ LC C G+V C+ A P+ CP +G EY
Sbjct: 743 CHYRGSVYQPGELIPTPSG---LCQCSNGTVKCDELAT-------PSAVHICP--EGKEY 790
Query: 722 LGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYH 781
+ FPDP P G V C C + PS C C
Sbjct: 791 F------DCRFPDPELP-------AGGVNC-ETTCANLAMNFTCTPSSPCISGC------ 830
Query: 782 GVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821
C+ C+ G C PC PA+C
Sbjct: 831 ----------------VCAPGVCRRGMFNCTYYPC-PAVC 853
Score = 43.5 bits (101), Expect = 0.002
Identities = 63/268 (23%), Positives = 87/268 (32%), Gaps = 62/268 (23%)
Query: 830 FCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSC 889
F P CH +S G +Q GS C A P+ + Q++
Sbjct: 627 FAP-CHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVV 685
Query: 890 CPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD--- 946
C + G L H CSS H + + QC CA+ P
Sbjct: 686 CQK--GMLYHH---------------CSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFY 728
Query: 947 ------CCP--QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS 998
C P C C + G Y+PGE P +C C +++C PS
Sbjct: 729 EDTLNFCVPIFHCR-CHYRGSVYQPGELI---PTPSGLCQC-----SNGTVKCDELATPS 779
Query: 999 LVG-CP----------PSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYT---C 1044
V CP P LP G +C TCA N + P PC + C
Sbjct: 780 AVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFT-------CTPSSPCISGCVC 832
Query: 1045 Q---CQDLTWLCIHQACPELSCPLSERH 1069
C+ + C + CP + +RH
Sbjct: 833 APGVCRRGMFNCTYYPCPAVCTIYGDRH 860
Score = 40.4 bits (93), Expect = 0.013
Identities = 72/315 (22%), Positives = 102/315 (32%), Gaps = 91/315 (28%)
Query: 126 CGPQAHLPHCRGCSQNGQTYG--------NGETFSP----------------DACTT-CR 160
C H+P C+ N Q G + E F+P DAC
Sbjct: 594 CFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSS 653
Query: 161 CLTGAVQCQGPSCSELNC-LESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCL 219
CL A+ C + ++ T C +C + G + H + C L
Sbjct: 654 CLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC--QKGMLYHHCSSFCLHS-----CISL 706
Query: 220 EGHIQCRQRECASLCPYPA----RPLPGTCCPVCD-GCFLNGREHRSGEPVGSGDPCSHC 274
QC +CA C P C P+ C G ++ GE + + P C
Sbjct: 707 SSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT--PSGLC 763
Query: 275 RCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRC 334
+C+NG+V+C+ L P CP +G EY ++ E
Sbjct: 764 QCSNGTVKCDELATPSAV---------HICP--EGKEYFDCRFPDPE------------- 799
Query: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPC-TACVCQD 393
AG V+CE T CA A P+ PC + CVC
Sbjct: 800 -LPAGGVNCE------TTCANLAMNFTCTPS------------------SPCISGCVCAP 834
Query: 394 GVPKCGAVLCPPAPC 408
GV + G C PC
Sbjct: 835 GVCRRGMFNCTYYPC 849
Score = 38.9 bits (89), Expect = 0.038
Identities = 39/134 (29%), Positives = 46/134 (34%), Gaps = 16/134 (11%)
Query: 521 CPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQC--LARR 578
CP C P C + G Y G P PS LC+C +G V+C LA
Sbjct: 722 CPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSG---LCQCSNGTVKCDELATP 778
Query: 579 CVPLPCPEPVLLPGECCPQCPAPAG---CPRPGAAHARHQEYFSPPGDPC-RRCLCLD-- 632
CPE P PAG C A A + P PC C+C
Sbjct: 779 SAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLA--MNFTCTPSSPCISGCVCAPGV 836
Query: 633 ---GSVSCQRLPCP 643
G +C PCP
Sbjct: 837 CRRGMFNCTYYPCP 850
Score = 34.7 bits (78), Expect = 0.71
Identities = 31/136 (22%), Positives = 46/136 (33%), Gaps = 20/136 (14%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNG---QTYGNGETFSPDACTTCRCLTGAVQCQGPSC 173
C D +C +A + R CS G Q + + D C + C P+C
Sbjct: 291 CKTDDDETYC--RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC 348
Query: 174 --------SELNCLESCTPP-------GECCPICCTEGGSHWEHGQEWTTPGDPCRICRC 218
S L+CL+ C P G C + G H + C C C
Sbjct: 349 TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECVC 408
Query: 219 LEGHIQCRQRECASLC 234
+ G C +++C C
Sbjct: 409 VGGVWNCTEQDCPVQC 424
Score = 34.3 bits (77), Expect = 0.93
Identities = 74/331 (22%), Positives = 106/331 (32%), Gaps = 77/331 (23%)
Query: 111 PDACTACVCQDGAAHCGPQAHLPHCRGCSQNG--QTYGNGETFSPDACTTCRCLTGAVQC 168
PD C+ C +G + + P R C + G T + C C G V
Sbjct: 1696 PDYCSLS-CPEG------KEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLH 1748
Query: 169 QGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLE-GHIQCRQ 227
+ S C P EC C G+ W D C + +CLE G I +
Sbjct: 1749 RPHSAQ-------CIPEKECA--CTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIE 1799
Query: 228 REC----ASLCPYPARPLPG-----TCCP--VCDGCFLNGREH------RSGEPVGSGDP 270
+C +C A + G TCC VC GC E S + + P
Sbjct: 1800 PDCDEEPTPVCEREAEVVMGIIDKWTCCSKEVC-GCDTTLCETSIPTCTNSQKLIVGHSP 1858
Query: 271 CSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL 330
S C C +C+PL CP + P C ++ F +Q R
Sbjct: 1859 LS-C-CPQYKCECDPLKCPSI-----------STPEC-----------REDQFMIQVR-- 1892
Query: 331 CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACV 390
+E+ C +P + S + P C DGE + P CV
Sbjct: 1893 -------------QEEPCCFSPFCVCESCTKPVPLCH-DGEFLTVDLNSTHFCCPQYYCV 1938
Query: 391 CQDGVPKCGAVLCPPAPCQHPTQPPGACCPS 421
C+ + + C G CCP+
Sbjct: 1939 CEPNLCPMPLLNCAEDMNLVKENVSGQCCPT 1969
Score = 32.7 bits (73), Expect = 2.7
Identities = 64/287 (22%), Positives = 89/287 (31%), Gaps = 72/287 (25%)
Query: 375 EGVQWEPDGRPCTACVC---------------QDGVPKCGAVLCPPAPCQHPTQPPGACC 419
EG +++P RPC A C +D V K G VL P Q + AC
Sbjct: 1705 EGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACT 1764
Query: 420 PS--------------CDSCTYHSQVYANGQNF---TDAD-SPCHACHCQDGTVTCSLVD 461
S D CT + + NG D D P C ++ V ++D
Sbjct: 1765 DSEDQPRTAGEIWNGGIDECTLY-KCLENGSIIPIEPDCDEEPTPVCE-REAEVVMGIID 1822
Query: 462 CPPTTCARPQSG--PGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPR 519
T C++ G C P C +++ V G S P C + +C+ C P
Sbjct: 1823 -KWTCCSKEVCGCDTTLCETSIPTCTNSQKLIV-GHS---PLSCCPQYKCE-----CDPL 1872
Query: 520 PCPRAPCAH----------PLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS 569
CP CC + C K P D +
Sbjct: 1873 KCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCC 1932
Query: 570 GNVQCLARRCVPLPCPEPVL------------LPGECCPQCPAPAGC 604
C+ C P CP P+L + G+CCP C
Sbjct: 1933 PQYYCV---CEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNC 1976
Score = 32.3 bits (72), Expect = 3.5
Identities = 34/145 (23%), Positives = 49/145 (33%), Gaps = 21/145 (14%)
Query: 215 ICRCLEGHIQCRQR-ECASLCPYPARPLPG------TCCPVCDGCFLNGREHRSGEPVGS 267
+C+ + CR E A C + P+ C CD F+ HR
Sbjct: 290 LCKTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFV----HRDCISCCP 345
Query: 268 GDPCSHCRCANGSVQC-EPLPCPPVPCRHPGK-IPGQCCPVCDGCEYQGHQYQSQETFRL 325
+C ++ C + CP G I + CP C + G Y
Sbjct: 346 PTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCP----CGFHGLAYSVGSKIEQ 401
Query: 326 QERGLCVRCSCQAGEVSCEEQECPV 350
+ C C C G +C EQ+CPV
Sbjct: 402 E----CTECVCVGGVWNCTEQDCPV 422
Score = 32.3 bits (72), Expect = 3.5
Identities = 27/106 (25%), Positives = 33/106 (31%), Gaps = 25/106 (23%)
Query: 379 WEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQP--------PGACCP--------SC 422
W D CT C D + C P C Q G CP +C
Sbjct: 320 WRDDFPACTD-KCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTC 378
Query: 423 DS-----CTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCP 463
S C +H Y+ G + C C C G C+ DCP
Sbjct: 379 ISLENCPCGFHGLAYSVGSKI---EQECTECVCVGGVWNCTEQDCP 421
Score = 32.3 bits (72), Expect = 3.5
Identities = 54/225 (24%), Positives = 73/225 (32%), Gaps = 40/225 (17%)
Query: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQ-PEGPPSLRCHRRQCPSLVGC-- 1002
D C Q ++ G+ +QP PCE C Q G S R C VG
Sbjct: 1688 DICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVL 1747
Query: 1003 --PPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQC-QDLTWLCIHQACP 1059
P S P + C + E G D C +C ++ + + I C
Sbjct: 1748 HRPHSAQCIPEKECACTDSEDQPRTAGEIWNGG----IDECTLYKCLENGSIIPIEPDCD 1803
Query: 1060 ELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASG--ERWTVDTCTSCSCMAGTVRCQ 1117
E P+ ER EV G ++WT C+ C T C+
Sbjct: 1804 EEPTPVCEREA---------------------EVVMGIIDKWT--CCSKEVCGCDTTLCE 1840
Query: 1118 SQRCSPLSCGPDK-APALSPGSCCP--RCLPRPASCMAFGDPHYR 1159
+ P K SP SCCP +C P C + P R
Sbjct: 1841 TS--IPTCTNSQKLIVGHSPLSCCPQYKCECDPLKCPSISTPECR 1883
Score = 32.0 bits (71), Expect = 4.6
Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 27/131 (20%)
Query: 697 KACAPALCPFPARGDCCPDC-DGCEYLGESYLSNQEFPDPREPCNL-CTCLGGFVTCGRR 754
+AC+ A P D P C D C+ +S++ C CLG + C
Sbjct: 308 RACSHAGYPIQDWRDDFPACTDKCD---DSFVHRDCISCCPPTCTFEKQCLGSNLHC--- 361
Query: 755 PCEPPGCSHP---LIPSGHC-----CPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQE 806
GC P ++ +G C CP C +HG+ + G + + C+ C C
Sbjct: 362 ---LDGCYCPDGLVMDNGTCISLENCP----CGFHGLAYSVGSKI----EQECTECVCVG 410
Query: 807 GSMRCQKKPCP 817
G C ++ CP
Sbjct: 411 GVWNCTEQDCP 421
Score = 31.2 bits (69), Expect = 7.9
Identities = 38/152 (25%), Positives = 50/152 (32%), Gaps = 43/152 (28%)
Query: 579 CVPLPCPEPVLLPGECCPQCPAPAG---------CPRPGAAHARHQEYFSPPGD----PC 625
C+ L PE +C C P G C ++ PG+ P
Sbjct: 703 CISLSSPEQC--SDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPS 760
Query: 626 RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSP------- 678
C C +G+V C L P A H CP +GKE+ RFP P
Sbjct: 761 GLCQCSNGTVKCDELATPSA--VH-----ICP-------EGKEYFDC-RFPDPELPAGGV 805
Query: 679 ---TAACHLCL---CWEGSVSCEPKACAPALC 704
T +L + C S CAP +C
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVC 837
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.512
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,861,838
Number of Sequences: 37866
Number of extensions: 5985787
Number of successful extensions: 30479
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 437
Number of HSP's that attempted gapping in prelim test: 17891
Number of HSP's gapped (non-prelim): 5456
length of query: 1503
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1388
effective length of database: 13,892,928
effective search space: 19283384064
effective search space used: 19283384064
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.