BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo sapiens] (372 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 782 0.0 gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 782 0.0 gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 782 0.0 gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 337 1e-92 gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 165 5e-41 gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 138 7e-33 gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 138 7e-33 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 125 6e-29 gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 125 6e-29 gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 125 6e-29 gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 125 6e-29 gi|26190608 synaptojanin 2 [Homo sapiens] 123 3e-28 gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 103 2e-22 gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 94 3e-19 gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 94 3e-19 gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 75 1e-13 gi|119943086 Tax1 (human T-cell leukemia virus type I) binding p... 42 9e-04 gi|21361682 Tax1 (human T-cell leukemia virus type I) binding pr... 42 9e-04 gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 40 0.003 gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 37 0.022 gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens] 32 1.2 gi|66392146 RNA U, small nuclear RNA export adaptor (phosphoryla... 30 3.5 gi|62241001 conserved helix-loop-helix ubiquitous kinase [Homo s... 29 6.0 gi|27477111 step II splicing factor SLU7 [Homo sapiens] 29 6.0 gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ... 29 7.8 gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ... 29 7.8 gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 29 7.8 >gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo sapiens] Length = 372 Score = 782 bits (2020), Expect = 0.0 Identities = 372/372 (100%), Positives = 372/372 (100%) Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL Sbjct: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60 Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR Sbjct: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120 Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300 Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360 Query: 361 REDPLGEAQPQI 372 REDPLGEAQPQI Sbjct: 361 REDPLGEAQPQI 372 >gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo sapiens] Length = 372 Score = 782 bits (2020), Expect = 0.0 Identities = 372/372 (100%), Positives = 372/372 (100%) Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL Sbjct: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60 Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR Sbjct: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120 Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300 Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360 Query: 361 REDPLGEAQPQI 372 REDPLGEAQPQI Sbjct: 361 REDPLGEAQPQI 372 >gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo sapiens] Length = 448 Score = 782 bits (2020), Expect = 0.0 Identities = 372/372 (100%), Positives = 372/372 (100%) Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL Sbjct: 77 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 136 Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR Sbjct: 137 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 196 Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY Sbjct: 197 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 256 Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG Sbjct: 257 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 316 Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY Sbjct: 317 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 376 Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL Sbjct: 377 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 436 Query: 361 REDPLGEAQPQI 372 REDPLGEAQPQI Sbjct: 437 REDPLGEAQPQI 448 >gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A [Homo sapiens] Length = 638 Score = 337 bits (864), Expect = 1e-92 Identities = 167/355 (47%), Positives = 221/355 (62%), Gaps = 3/355 (0%) Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60 MD L P +F+ VS VRMQG++LL+FAKY HLP+++ + T T TGL GYWGNKGGV++ L Sbjct: 120 MDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRL 179 Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120 +G+ + +NCHLP H+ QR ++F IL +Q +G ILDHDL+ WFGD+NFR Sbjct: 180 AAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFR 239 Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 IE + LHFV+ +I + LWEKDQL++AK P+L+ FQEG L F PT+KFD +N Y Sbjct: 240 IESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKY 299 Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 DTS KKRKPAWTDRILW++K P GP + ++ Y SHM Y +SDHKPV+ Sbjct: 300 DTSAKKRKPAWTDRILWKVK-APGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAA 358 Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300 F L+ PL+ L D W +V Y + F S WDWIGLY+VG R DY Sbjct: 359 QFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDY 418 Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQI 355 V+Y W V N QV ++P +F+L YYS++ ++GI+ PFQI Sbjct: 419 VAYVWAKHEDV--DGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQI 471 >gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor [Homo sapiens] Length = 913 Score = 165 bits (418), Expect = 5e-41 Identities = 90/243 (37%), Positives = 135/243 (55%), Gaps = 21/243 (8%) Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 + KV +R+ GI+LL++ K +H YI + ++ TG+ G GNKGGV I + + + Sbjct: 336 YAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSIC 395 Query: 69 IINCHLPPHISNNYQRLEHFDRILE-MQNCE-GRDIP--NILDHDLIIWFGDMNFRIEDF 124 ++N HL HI +R + + I MQ C+ +P I +HD+I+W GD+N+RIE+ Sbjct: 396 VVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEEL 455 Query: 125 GLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSE 184 + V++ I+ + + L+ DQL I + F EG L F PTYK+D S+D+DTSE Sbjct: 456 DVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSE 515 Query: 185 KKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDL 244 K R PAW DRILW+ K +++ Y SHM SDHKPVS FD+ Sbjct: 516 KCRAPAWCDRILWKGK-----------------NITQLSYQSHMALKTSDHKPVSSVFDI 558 Query: 245 ELK 247 ++ Sbjct: 559 GVR 561 >gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase isoform b [Homo sapiens] Length = 893 Score = 138 bits (348), Expect = 7e-33 Identities = 81/247 (32%), Positives = 129/247 (52%), Gaps = 21/247 (8%) Query: 5 SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYG 64 S + KV VR+ G++LL+FA+ YI+ ++T++ TG+ G GNKGGV + + Sbjct: 307 SKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHN 366 Query: 65 YYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFGDMNFR 120 I+N HL H+ + +R + + I + + +P NI+ H+++IW GD+N+R Sbjct: 367 TTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYR 426 Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 + + V+ I + L + DQL+I + +F EG + F PTYK+D ++ + Sbjct: 427 LCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRW 486 Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 D+S K R PAW DRILWR +++ Y SHM SDHKPVS Sbjct: 487 DSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDHKPVSA 529 Query: 241 TFDLELK 247 F + +K Sbjct: 530 LFHIGVK 536 >gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase isoform a [Homo sapiens] Length = 901 Score = 138 bits (348), Expect = 7e-33 Identities = 81/247 (32%), Positives = 129/247 (52%), Gaps = 21/247 (8%) Query: 5 SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYG 64 S + KV VR+ G++LL+FA+ YI+ ++T++ TG+ G GNKGGV + + Sbjct: 307 SKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHN 366 Query: 65 YYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFGDMNFR 120 I+N HL H+ + +R + + I + + +P NI+ H+++IW GD+N+R Sbjct: 367 TTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYR 426 Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180 + + V+ I + L + DQL+I + +F EG + F PTYK+D ++ + Sbjct: 427 LCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRW 486 Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240 D+S K R PAW DRILWR +++ Y SHM SDHKPVS Sbjct: 487 DSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDHKPVSA 529 Query: 241 TFDLELK 247 F + +K Sbjct: 530 LFHIGVK 536 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 125 bits (314), Expect = 6e-29 Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%) Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 ++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + + Sbjct: 625 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 684 Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127 + H S +R E F I + GR + HD + W GD N+RI D Sbjct: 685 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 740 Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187 V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R Sbjct: 741 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 800 Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236 PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+ Sbjct: 801 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 860 Query: 237 PVSGTFDLEL 246 PV D+++ Sbjct: 861 PVVALIDIDI 870 >gi|237757310 synaptojanin 1 isoform a [Homo sapiens] Length = 1612 Score = 125 bits (314), Expect = 6e-29 Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%) Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 ++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + + Sbjct: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723 Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127 + H S +R E F I + GR + HD + W GD N+RI D Sbjct: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779 Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187 V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R Sbjct: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839 Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236 PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+ Sbjct: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899 Query: 237 PVSGTFDLEL 246 PV D+++ Sbjct: 900 PVVALIDIDI 909 >gi|237757308 synaptojanin 1 isoform b [Homo sapiens] Length = 1350 Score = 125 bits (314), Expect = 6e-29 Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%) Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 ++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + + Sbjct: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723 Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127 + H S +R E F I + GR + HD + W GD N+RI D Sbjct: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779 Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187 V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R Sbjct: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839 Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236 PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+ Sbjct: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899 Query: 237 PVSGTFDLEL 246 PV D+++ Sbjct: 900 PVVALIDIDI 909 >gi|237757326 synaptojanin 1 isoform d [Homo sapiens] Length = 1526 Score = 125 bits (314), Expect = 6e-29 Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%) Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 ++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + + Sbjct: 620 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 679 Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127 + H S +R E F I + GR + HD + W GD N+RI D Sbjct: 680 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 735 Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187 V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R Sbjct: 736 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 795 Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236 PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+ Sbjct: 796 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 855 Query: 237 PVSGTFDLEL 246 PV D+++ Sbjct: 856 PVVALIDIDI 865 >gi|26190608 synaptojanin 2 [Homo sapiens] Length = 1496 Score = 123 bits (308), Expect = 3e-28 Identities = 81/252 (32%), Positives = 123/252 (48%), Gaps = 18/252 (7%) Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 +I ++ ++ G+ L +F + H+P+I+ ++ + TG+ G GNKG V I + + Sbjct: 621 YILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFC 680 Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNC--EGRDIPNILDHDLIIWFGDMNFRIEDFGL 126 I HL S +R E + I + + C GR N+ HD + W GD N+RI D Sbjct: 681 FICSHLTAGQSQVKERNEDYKEITQ-KLCFPMGR---NVFSHDYVFWCGDFNYRI-DLTY 735 Query: 127 HFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKK 186 V +K + + L E DQL + K + ++F EG + F PTYK+D S YDTS+K Sbjct: 736 EEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKC 795 Query: 187 RKPAWTDRILWRLKRQP---CAGP--------DTPIPPASHFSLSLRGYSSHMTYGISDH 235 R PAWTDR+LW K+ P AG D +S Y SDH Sbjct: 796 RTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRAELQASDH 855 Query: 236 KPVSGTFDLELK 247 +PV ++E++ Sbjct: 856 RPVLAIVEVEVQ 867 >gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens] Length = 1258 Score = 103 bits (257), Expect = 2e-22 Identities = 70/252 (27%), Positives = 114/252 (45%), Gaps = 27/252 (10%) Query: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63 L+ L + ++ + I + V K +H I +ST S TG+ GNKG V + Sbjct: 492 LTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFN 551 Query: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDL----IIWFGDMNF 119 G +NCHL +R +++ IL + + R + N D L + WFGD+N+ Sbjct: 552 GTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQL-NAFDISLRFTHLFWFGDLNY 610 Query: 120 RIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSND 179 R+ D + + I + + L DQL++ ++ + F E + FPPTY+++R S D Sbjct: 611 RL-DMDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRD 669 Query: 180 -------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGI 232 T + P+W DRILW+ P +H + G + + Sbjct: 670 TYAWHKQKPTGVRTNVPSWCDRILWKSY------------PETHIICNSYGCTDDIV--T 715 Query: 233 SDHKPVSGTFDL 244 SDH PV GTF++ Sbjct: 716 SDHSPVFGTFEV 727 >gi|40254823 SH2 containing inositol phosphatase isoform b [Homo sapiens] Length = 1188 Score = 93.6 bits (231), Expect = 3e-19 Identities = 66/252 (26%), Positives = 111/252 (44%), Gaps = 26/252 (10%) Query: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63 ++ ++F V+ + I ++V AK +H I + T + TG+ GNKG V + Sbjct: 471 ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFN 530 Query: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDI-PNILDHDL--IIWFGDMNFR 120 G + +N HL +R +++ IL + + P + H + WFGD+N+R Sbjct: 531 GTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYR 590 Query: 121 IE--DFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSN 178 ++ + + + IK + Y L DQL ++ + F+E + F PTY+F+R + Sbjct: 591 VDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTR 650 Query: 179 D-------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYG 231 D T K P+W DR+LW+ P H + + Y S Sbjct: 651 DKYAYTKQKATGMKYNLPSWCDRVLWKSY------------PLVH--VVCQSYGSTSDIM 696 Query: 232 ISDHKPVSGTFD 243 SDH PV TF+ Sbjct: 697 TSDHSPVFATFE 708 >gi|64085167 SH2 containing inositol phosphatase isoform a [Homo sapiens] Length = 1189 Score = 93.6 bits (231), Expect = 3e-19 Identities = 66/252 (26%), Positives = 111/252 (44%), Gaps = 26/252 (10%) Query: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63 ++ ++F V+ + I ++V AK +H I + T + TG+ GNKG V + Sbjct: 472 ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFN 531 Query: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDI-PNILDHDL--IIWFGDMNFR 120 G + +N HL +R +++ IL + + P + H + WFGD+N+R Sbjct: 532 GTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYR 591 Query: 121 IE--DFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSN 178 ++ + + + IK + Y L DQL ++ + F+E + F PTY+F+R + Sbjct: 592 VDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTR 651 Query: 179 D-------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYG 231 D T K P+W DR+LW+ P H + + Y S Sbjct: 652 DKYAYTKQKATGMKYNLPSWCDRVLWKSY------------PLVH--VVCQSYGSTSDIM 697 Query: 232 ISDHKPVSGTFD 243 SDH PV TF+ Sbjct: 698 TSDHSPVFATFE 709 >gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] Length = 644 Score = 74.7 bits (182), Expect = 1e-13 Identities = 59/213 (27%), Positives = 96/213 (45%), Gaps = 36/213 (16%) Query: 53 KGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDH---- 108 KG + I +G I H +RL + R ++ R++P+ + Sbjct: 404 KGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLP-RNVPDTNPYRSSA 462 Query: 109 -------DLIIWFGDMNFRIEDFGLHFVRESIKNRCYG------GLWEKDQLSIAKKHDP 155 D + WFGD NFR+ G V +++ C G L + DQL + Sbjct: 463 ADVTTRFDEVFWFGDFNFRLS--GGRTVVDALL--CQGLVVDVPALLQHDQLIREMRKGS 518 Query: 156 LLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPAS 215 + + FQE + F P+YKFD + YD++ K+R P++TDR+L+R + + G P+ Sbjct: 519 IFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHK---GDICPV---- 571 Query: 216 HFSLSLRGYSSHMTYGISDHKPVSGTFDLELKP 248 YSS SDH+PV G F ++++P Sbjct: 572 -------SYSSCPGIKTSDHRPVYGLFRVKVRP 597 >gi|119943086 Tax1 (human T-cell leukemia virus type I) binding protein 1 isoform b [Homo sapiens] Length = 747 Score = 42.0 bits (97), Expect = 9e-04 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 12/100 (12%) Query: 273 YSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAW-------VGDSKVSCSDNLNQVYIDIS 325 Y+ T P DW+G++KVG DY ++ W V S V+C Y Sbjct: 36 YTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYY---- 91 Query: 326 NIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPL 365 +P + EF Y + G S PFQ S E+ L Sbjct: 92 -LPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELL 130 >gi|21361682 Tax1 (human T-cell leukemia virus type I) binding protein 1 isoform a [Homo sapiens] Length = 789 Score = 42.0 bits (97), Expect = 9e-04 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 12/100 (12%) Query: 273 YSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAW-------VGDSKVSCSDNLNQVYIDIS 325 Y+ T P DW+G++KVG DY ++ W V S V+C Y Sbjct: 36 YTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYY---- 91 Query: 326 NIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPL 365 +P + EF Y + G S PFQ S E+ L Sbjct: 92 -LPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELL 130 >gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] Length = 446 Score = 40.4 bits (93), Expect = 0.003 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 260 EDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWV--GDSKVSCSDNL 317 E + D+ Y+ T F DWIG+++VG + +Y ++ WV + S Sbjct: 29 EKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFMWVTLPIDLNNKSAKQ 88 Query: 318 NQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPP 357 +V +P ++ + CY V G S PFQ P Sbjct: 89 QEVQFKAYYLPKDDEYYQFCYVDED-GVVRGASIPFQFRP 127 >gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo sapiens] Length = 691 Score = 37.4 bits (85), Expect = 0.022 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 2/72 (2%) Query: 285 DWIGLYKVGLRDVNDYVSYAW--VGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNS 342 DWIG++KV V DY ++ W V +S S V S +P + Y N Sbjct: 46 DWIGIFKVEAACVRDYHTFVWSSVPESTTDGSPIHTSVQFQASYLPKPGAQLYQFRYVNR 105 Query: 343 LRSVVGISRPFQ 354 V G S PFQ Sbjct: 106 QGQVCGQSPPFQ 117 >gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens] Length = 412 Score = 31.6 bits (70), Expect = 1.2 Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 20/79 (25%) Query: 167 FPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSS 226 FPP+Y + ++ + R PAW DRIL P A L Sbjct: 323 FPPSYPYSEDARQGEQYMNTRCPAWCDRILMS-------------PSAKELVLRSESEEK 369 Query: 227 HMTYG-------ISDHKPV 238 +TY + DHKPV Sbjct: 370 VVTYDHIGPNVCMGDHKPV 388 >gi|66392146 RNA U, small nuclear RNA export adaptor (phosphorylation regulated) [Homo sapiens] Length = 394 Score = 30.0 bits (66), Expect = 3.5 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 2/67 (2%) Query: 154 DPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPP 213 D +R FQ P + R D+SE+ + D LW+ KRQ C P P P Sbjct: 38 DSAMRAFQNTATACAPVSHY-RAVESVDSSEESFSDSDDDSCLWKRKRQKCFNP-PPKPE 95 Query: 214 ASHFSLS 220 F S Sbjct: 96 PFQFGQS 102 >gi|62241001 conserved helix-loop-helix ubiquitous kinase [Homo sapiens] Length = 745 Score = 29.3 bits (64), Expect = 6.0 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 219 LSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSD 278 L L YS MTYGIS K + ++E K + A + V + +E+ +M ++ + Sbjct: 489 LDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGV-----IGYLEDQIMSLHAEIME 543 Query: 279 FPSSPW 284 SP+ Sbjct: 544 LQKSPY 549 >gi|27477111 step II splicing factor SLU7 [Homo sapiens] Length = 586 Score = 29.3 bits (64), Expect = 6.0 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 6/64 (9%) Query: 151 KKHDPLLREF--QEGRLLF-PPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGP 207 KKH+ L + +E RLL T + D Y++ + R+P + +R+KRQ P Sbjct: 520 KKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQ---RP 576 Query: 208 DTPI 211 D P+ Sbjct: 577 DDPM 580 >gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A isoform 2 [Homo sapiens] Length = 548 Score = 28.9 bits (63), Expect = 7.8 Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%) Query: 157 LREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASH 216 LR + L P +++ +++D E+KRK + + +K+ P +GP P PP Sbjct: 269 LRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTY-ETFKSIMKKSPFSGPTDPRPPPRR 327 Query: 217 FSLSLRGYSS 226 ++ R +S Sbjct: 328 IAVPSRSSAS 337 >gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A isoform 1 [Homo sapiens] Length = 551 Score = 28.9 bits (63), Expect = 7.8 Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%) Query: 157 LREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASH 216 LR + L P +++ +++D E+KRK + + +K+ P +GP P PP Sbjct: 272 LRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTY-ETFKSIMKKSPFSGPTDPRPPPRR 330 Query: 217 FSLSLRGYSS 226 ++ R +S Sbjct: 331 IAVPSRSSAS 340 >gi|219521893 coiled-coil transcriptional coactivator isoform 2 [Homo sapiens] Length = 606 Score = 28.9 bits (63), Expect = 7.8 Identities = 10/21 (47%), Positives = 14/21 (66%) Query: 285 DWIGLYKVGLRDVNDYVSYAW 305 DWIG++KV V DY ++ W Sbjct: 46 DWIGIFKVEAACVRDYHTFVW 66 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.140 0.448 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,138,348 Number of Sequences: 37866 Number of extensions: 761234 Number of successful extensions: 1606 Number of sequences better than 10.0: 27 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 1549 Number of HSP's gapped (non-prelim): 30 length of query: 372 length of database: 18,247,518 effective HSP length: 104 effective length of query: 268 effective length of database: 14,309,454 effective search space: 3834933672 effective search space used: 3834933672 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.