Search of human proteins with 207113124

Search of human proteins with 207113124

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|207113124 dynein, cytoplasmic 1, intermediate chain 1
isoform c [Homo sapiens]
         (608 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform...  1240   0.0  
gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform...  1228   0.0  
gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a...  1217   0.0  
gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa...   965   0.0  
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]              115   9e-26
gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens]      103   6e-22
gi|66267730 WD repeat domain 34 [Homo sapiens]                         99   9e-21
gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo ...    93   8e-19
gi|217272887 WD repeat domain 63 [Homo sapiens]                        57   4e-08
gi|155030242 WD repeat domain 60 [Homo sapiens]                        55   1e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     54   5e-07
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     54   5e-07
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    54   5e-07
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    54   5e-07
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    54   5e-07
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    54   5e-07
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    54   5e-07
gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]                  51   3e-06
gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]                  51   3e-06
gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]                  51   3e-06
gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]                   51   3e-06
gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]                   51   3e-06
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]             50   5e-06
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]              49   1e-05
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa...    49   1e-05
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa...    49   1e-05
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi...    49   1e-05
gi|161702986 ezrin [Homo sapiens]                                      49   2e-05
gi|21614499 ezrin [Homo sapiens]                                       49   2e-05
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     48   3e-05

>gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform c
           [Homo sapiens]
          Length = 608

 Score = 1240 bits (3208), Expect = 0.0
 Identities = 608/608 (100%), Positives = 608/608 (100%)

Query: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
           MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60

Query: 61  ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVD 120
           ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVD
Sbjct: 61  ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVD 120

Query: 121 FLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELT 180
           FLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELT
Sbjct: 121 FLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELT 180

Query: 181 EEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNR 240
           EEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNR
Sbjct: 181 EEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNR 240

Query: 241 QFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVF 300
           QFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVF
Sbjct: 241 QFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVF 300

Query: 301 HCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNV 360
           HCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNV
Sbjct: 301 HCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNV 360

Query: 361 VGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVV 420
           VGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVV
Sbjct: 361 VGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVV 420

Query: 421 GSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLW 480
           GSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLW
Sbjct: 421 GSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLW 480

Query: 481 TTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG 540
           TTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG
Sbjct: 481 TTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG 540

Query: 541 ASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEE 600
           ASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEE
Sbjct: 541 ASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEE 600

Query: 601 EGTVELSA 608
           EGTVELSA
Sbjct: 601 EGTVELSA 608


>gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform b
           [Homo sapiens]
          Length = 628

 Score = 1228 bits (3177), Expect = 0.0
 Identities = 608/628 (96%), Positives = 608/628 (96%), Gaps = 20/628 (3%)

Query: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
           MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60

Query: 61  ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTR--------------- 105
           ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTR               
Sbjct: 61  ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 120

Query: 106 -----RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 160
                RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS
Sbjct: 121 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 180

Query: 161 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 220
           ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG
Sbjct: 181 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 240

Query: 221 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 280
           RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP
Sbjct: 241 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 300

Query: 281 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 340
           DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP
Sbjct: 301 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 360

Query: 341 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 400
           VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS
Sbjct: 361 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 420

Query: 401 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 460
           KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG
Sbjct: 421 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 480

Query: 461 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 520
           PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL
Sbjct: 481 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 540

Query: 521 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 580
           DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE
Sbjct: 541 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 600

Query: 581 WTRFARTLVEIRANRADSEEEGTVELSA 608
           WTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 601 WTRFARTLVEIRANRADSEEEGTVELSA 628


>gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a
           [Homo sapiens]
          Length = 645

 Score = 1217 bits (3149), Expect = 0.0
 Identities = 608/645 (94%), Positives = 608/645 (94%), Gaps = 37/645 (5%)

Query: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
           MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60

Query: 61  ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL 103
           ALLQSIGISPEPPLV                 PTPMSPSSKSVSTPSEAGSQDSGDLGPL
Sbjct: 61  ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 120

Query: 104 TR--------------------RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 143
           TR                    RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE
Sbjct: 121 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 180

Query: 144 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 203
           EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV
Sbjct: 181 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 240

Query: 204 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 263
           IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP
Sbjct: 241 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 300

Query: 264 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 323
           ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT
Sbjct: 301 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 360

Query: 324 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 383
           YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL
Sbjct: 361 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 420

Query: 384 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 443
           DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF
Sbjct: 421 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 480

Query: 444 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 503
           EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW
Sbjct: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 540

Query: 504 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 563
           SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG
Sbjct: 541 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 600

Query: 564 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 608
           RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 601 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645


>gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
           sapiens]
          Length = 638

 Score =  965 bits (2495), Expect = 0.0
 Identities = 475/641 (74%), Positives = 542/641 (84%), Gaps = 36/641 (5%)

Query: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKE---PVQDDSDLDRKRR 57
           MSDKS+LKAELERKKQRLAQIREEKKRKEEERKKKE D  QKKE   PVQ++SDL++KRR
Sbjct: 1   MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETD--QKKEAVAPVQEESDLEKKRR 58

Query: 58  ETEALLQSIGISPEPPLV------PTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLH-- 109
           E EALLQS+G++PE P+V      P PMSPSSKSVSTPSEAGSQDSGD G +  R LH  
Sbjct: 59  EAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGD-GAVGSRTLHWD 117

Query: 110 -------------------KLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEE 150
                              KLG++K+TQVDF PRE+V+Y+KETQTP+     E++EED++
Sbjct: 118 TDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDD 177

Query: 151 MVESKVGQDSELENQDKKQEVKE--APPRELTEEEKQQILHSEEFLIFFDRTIRVIERAL 208
           +V  K   + E E   KK E  +  APP ELTEEEKQQILHSEEFL FFD + R++ERAL
Sbjct: 178 VVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERAL 237

Query: 209 AEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVA 268
           +E  +IFFDYSGR+LE+K+G++QAGA LS NRQF+DE WSKHRVV+C+DWS QYPEL+VA
Sbjct: 238 SEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVA 297

Query: 269 SYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQI 328
           SYNNNEDAPHEPDGVALVWNMK+KKTTPEYVFHCQS+VMS  FA+FHPNLVVGGTYSGQI
Sbjct: 298 SYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQI 357

Query: 329 VLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLST 388
           VLWDNRS++RTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLI++STDGK+CSWSLDMLS 
Sbjct: 358 VLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSH 417

Query: 389 PQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQG 448
           PQ+SMELV+ +SK VAVT M+FP GDVNNFVVGSEEG+VYTACRHGSKAGI E+FEGHQG
Sbjct: 418 PQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQG 477

Query: 449 PVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHP 508
           P+TGI+CH AVG +DFSHLFVTSSFDWTVKLWTTK+NKPLYSFEDNADYVYDVMWSP HP
Sbjct: 478 PITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHP 537

Query: 509 ALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVY 568
           ALFACVDGMGRLDLWNLNNDTEVPTAS+++EG  ALNRVRW  +G+E+AVGDSEG+I +Y
Sbjct: 538 ALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIY 597

Query: 569 DVGE-LAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 608
           DVGE +AVP NDEW RF RTL EI ANRAD+EEE    + A
Sbjct: 598 DVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638


>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
          Length = 848

 Score =  115 bits (289), Expect = 9e-26
 Identities = 115/483 (23%), Positives = 206/483 (42%), Gaps = 72/483 (14%)

Query: 146 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEF---LIFFDRTI- 201
           ++D+ +  S   ++SE  +    + V  A   E  E+    IL S++F   L F +R + 
Sbjct: 353 DQDQRLPGSTTEKNSETSSLMDIENVILAKIHEDEEDHSDAILKSDKFHQDLFFMERVLM 412

Query: 202 -RVIERALA--------------EDSDIFFDYSGRELEE---KDGDVQAGANLSFNRQFY 243
             + +  LA              E  D+       E+EE   K+ + +  A  S      
Sbjct: 413 ENIFQPKLAAYRQLPVLKEPEPEEPEDVLESAKHEEVEEESKKEEEEEIHAEESTIPANL 472

Query: 244 DEHWS------KHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPE 297
           +  WS      K   V+ + W+   P+L+   Y +      +  G+A  W++K     PE
Sbjct: 473 ERLWSFSCDLTKGLNVSSLAWNKTNPDLLAVGYGHF-GFKEQKRGLACCWSIK-NPMWPE 530

Query: 298 YVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYC 357
            ++     V +V F+   PNL+  G ++G I +++ RS+   PV  +  S   H  PV+ 
Sbjct: 531 RIYQSPYGVTAVDFSIGAPNLLAVGYHNGTIAIYNVRSNSNVPVLDSSESPQKHLGPVWQ 590

Query: 358 VNVV-------GTQNAHNLITVSTDGKMCSWSL-------DML-------------STPQ 390
           +  +       G      L+++S DG++  W +       D++                +
Sbjct: 591 LQWIEQDRGTTGDGKREILVSISADGRISKWVIRKGLDCYDLMRLKRTTAASNKKGGEKE 650

Query: 391 ESMELVYNKSKPVAVTGM--AFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQG 448
           +  E + ++  P    GM  AF   D N ++ G+EEG ++  C         + + GH+G
Sbjct: 651 KKDEALISRQAP----GMCFAFHPKDTNIYLAGTEEGHIHK-CSCSYNEQYLDTYRGHKG 705

Query: 449 PVTGINCHMAVGPIDFSH-LFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVH 507
           PV  +  +       F H +F++ S DW V +W  ++ KP  SF      VYDV WSP  
Sbjct: 706 PVYKVTWN------PFCHDVFLSCSADWGVIIWQQENVKPSLSFYPATSVVYDVAWSPKS 759

Query: 508 PALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWV 567
             +FA  +   R+++W+L+  T  P              + +A+    + VGDS+G++ V
Sbjct: 760 SYIFAAAN-ENRVEIWDLHISTLDPLIVNTANPGIKFTTILFAKQTDCLLVGDSDGQVSV 818

Query: 568 YDV 570
           Y++
Sbjct: 819 YEL 821


>gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens]
          Length = 699

 Score =  103 bits (256), Expect = 6e-22
 Identities = 107/433 (24%), Positives = 188/433 (43%), Gaps = 44/433 (10%)

Query: 161 ELENQDKKQEVKEAPP-----------RELTEEEKQQILHSEEFLIFFDRTIRVIERALA 209
           ELE Q+K +E ++A             R+LT  E Q      + LI   +  +++ER + 
Sbjct: 237 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQT-----DDLIKLSQAAKIMERMVN 291

Query: 210 EDS--DIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMV 267
           +++  DI  D+   +    +   Q G  L   +   D+  +K   VT + W+ +Y +L  
Sbjct: 292 QNTYDDIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDK--AKRLSVTALCWNPKYRDLFA 349

Query: 268 ASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQ 327
             Y +  D   +  G+ L++++K   + PEY+F   S VM +     HP LV  G Y G 
Sbjct: 350 VGYGSY-DFMKQSRGMLLLYSLK-NPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGN 407

Query: 328 IVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNL--ITVSTDGKMCSWSL-- 383
           + +++ +     P   +   +  H+ PV+ V         NL   +VS+DG++ SW+L  
Sbjct: 408 VAIYNLKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVK 467

Query: 384 ------DMLSTPQESMELVYNKS---KPVAV-TGMAFPTGDVNNFVVGSEEGTVYTACRH 433
                 D++    E       +     PV   T   F       F+VG+EEG +Y  C  
Sbjct: 468 RKLVHIDVIKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIY-KCSK 526

Query: 434 GSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFED 493
              +   + ++ H   V  ++ +        + +F++ S DWTVK+W      P++ ++ 
Sbjct: 527 SYSSQFLDTYDAHNMSVDTVSWNPY-----HTKVFMSCSSDWTVKIWDHTIKTPMFIYDL 581

Query: 494 NADYVYDVMWSPVHPALFACVDGMGRLDLWNLN-NDTEVPTASVAIEGASALNRVRWAQA 552
           N+  V DV W+P    +FA V   G+  +++L  N  E           + L  V++   
Sbjct: 582 NS-AVGDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLI 640

Query: 553 GKEVAVGDSEGRI 565
              + VGD  G I
Sbjct: 641 HPIIIVGDDRGHI 653


>gi|66267730 WD repeat domain 34 [Homo sapiens]
          Length = 536

 Score = 99.4 bits (246), Expect = 9e-21
 Identities = 80/320 (25%), Positives = 146/320 (45%), Gaps = 41/320 (12%)

Query: 287 WNMKFKKTTPEY---VFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQR 343
           WN+  +   P+    V    S+V+ + F    P+ V GG YSG++++WD        + R
Sbjct: 198 WNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWR 257

Query: 344 TPLSAAAHTHPVYCVNVV---GTQNAHNLITVSTDGKMCSW--------------SLDML 386
           T L+   HT PV  V  +   G  +   +++V+TDGK+  W              +L M 
Sbjct: 258 TGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQ 317

Query: 387 STPQESMELVYNKSKP-VAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV--- 442
             P+ +    + + +  V  T +AF + D   F++G+E G          +A +  +   
Sbjct: 318 QLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSS 377

Query: 443 ----------FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFE 492
                     F  H GP+  ++C     P    +LF+++  D  V L++     PL S +
Sbjct: 378 VPLRAPAQFTFSPHGGPIYSVSC----SPFH-RNLFLSAGTDGHVHLYSMLQAPPLTSLQ 432

Query: 493 DNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASV-AIEGASALNRVRW-A 550
            +  Y++ V WSPV P +FA   G G + L++L   ++ PT  +   +  S +  + + +
Sbjct: 433 LSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNS 492

Query: 551 QAGKEVAVGDSEGRIWVYDV 570
           Q  + +A GD++G + V+ +
Sbjct: 493 QQTQLLAAGDAQGTVKVWQL 512


>gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
           sapiens]
          Length = 605

 Score = 92.8 bits (229), Expect = 8e-19
 Identities = 78/330 (23%), Positives = 144/330 (43%), Gaps = 21/330 (6%)

Query: 251 RVVTCMDWSLQYPELMVASYN--NNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMS 308
           R  T + W       +  +Y+  + + AP      + +W+++     PE      S +++
Sbjct: 163 RAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLE-NPNKPELALKPSSPLVT 221

Query: 309 VCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHN 368
           + F     ++++GG Y+GQI  WD R  + + V       ++H  PVY    + ++    
Sbjct: 222 LEFNPKDSHVLLGGCYNGQIACWDTR--KGSLVAELSTIESSHRDPVYGTIWLQSKTGTE 279

Query: 369 LITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPV----AVTGMAFPTGDVNNFVVGSEE 424
             + STDG++  W +  +S P E + L   K + +        + F +     F+VG+E+
Sbjct: 280 CFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQ 339

Query: 425 GTVYTACRHGSKAGIGEV---FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWT 481
           G V + C   +K    ++   F GH GP+  +  +       +   F+T   DWT ++W+
Sbjct: 340 GIVIS-CNRKAKTSAEKIVCTFPGHHGPIYALQRNPF-----YPKNFLTVG-DWTARIWS 392

Query: 482 TKHNKPLYSFED-NADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG 540
               +    +   +  Y+ D  WSPV P +F      G LD+W+   +   PT S+ +  
Sbjct: 393 EDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKV-C 451

Query: 541 ASALNRVRWAQAGKEVAVGDSEGRIWVYDV 570
             AL  +R    G  +A G   G   + +V
Sbjct: 452 DEALFCLRVQDNGCLIACGSQLGTTTLLEV 481


>gi|217272887 WD repeat domain 63 [Homo sapiens]
          Length = 891

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 21/199 (10%)

Query: 156 VGQDSELENQDKKQEVKEAP----PRELTEEEKQQILHSEEFLIFFDRTIRVIERALAED 211
           + Q  ++  Q K    K A     PRE +EEEK+ +  S+  + F +     +E AL ++
Sbjct: 235 IPQIKDISTQTKWTYPKNATTQYYPREFSEEEKETLKQSKPLVDFLNNASISVEIALQQN 294

Query: 212 S--DIFFDYSGRELEEKDGDV--QAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMV 267
              + F D   + L E++G    +   +L   + F D H    +++TC+ W      L+ 
Sbjct: 295 EIMNTFID-DWKYLAEEEGTFGDKTDTHLKEYQSFTDLHSPTEKMITCVSWHPTIYGLIA 353

Query: 268 ASYN---NNEDAPH-------EPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPN 317
            S     + ED  H       +P  + L W+       P+ +      +    F    PN
Sbjct: 354 VSVAVRLSFEDRVHFSGKLLLQPS-LILFWSFS-DPIHPQLMLESPDDIFCFKFCPSDPN 411

Query: 318 LVVGGTYSGQIVLWDNRSH 336
           ++ GG  +GQIV+WD  +H
Sbjct: 412 IIAGGCINGQIVMWDITAH 430



 Score = 30.0 bits (66), Expect = 6.5
 Identities = 12/32 (37%), Positives = 22/32 (68%)

Query: 12  ERKKQRLAQIREEKKRKEEERKKKEADMQQKK 43
           ER+ + L  + + KK +E+E+K+ E +M +KK
Sbjct: 812 EREVKHLEYVEQRKKIREQEKKEMELEMAKKK 843


>gi|155030242 WD repeat domain 60 [Homo sapiens]
          Length = 1066

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 70/350 (20%), Positives = 130/350 (37%), Gaps = 80/350 (22%)

Query: 283  VALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRS------- 335
            V  VW++ ++ + P+ V  C+S V   C +     L+  GT  G +V+WD R        
Sbjct: 677  VLCVWDI-WQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGSVVVWDLREDSRLHYS 735

Query: 336  ------------------------HRRTPVQRT-PLSAAAHTHPVYCVNVVGTQN----- 365
                                    + R+P+Q   P+S + H    + ++   TQ      
Sbjct: 736  VTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQSFVLSPFSTQEEMSGL 795

Query: 366  AHNLITVSTDGKMCSWSL-------------DMLSTPQESMELVYNKSKPVA-------- 404
            + ++ ++   G +  W +             D+   P   ++LV++    +         
Sbjct: 796  SFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVHSALIQLGDSLSHKGN 855

Query: 405  -------VTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHM 457
                      + F   D N+F++G++ G +    R   +    ++F+  Q  +  +    
Sbjct: 856  EFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVA-PKLFKPQQHGIRPVK--- 911

Query: 458  AVGPIDFSH----LFVTSSFDWTVKLWTTKHNKPLYSFEDNADY--VYDVMWSPVHPALF 511
             V  IDFS     +F+    D +++L       PL  ++ + D   V  + WSP  PA+F
Sbjct: 912  -VNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGLQWSPTRPAVF 970

Query: 512  ACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDS 561
               D    + +W+L      P   VA +  S    V  A  G+    G S
Sbjct: 971  LVQDDTSNIYIWDLLQSDLGP---VAKQQVSPNRLVAMAAVGEPEKAGGS 1017



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 22 REEKKRKEEE-RKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISP 70
          +EE+K +E++ RK+ E D+ + KEP   D D D + R+  A + +   SP
Sbjct: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESP 80



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 37/200 (18%), Positives = 78/200 (39%), Gaps = 21/200 (10%)

Query: 2   SDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQK-KEPVQDDSDLDRKRRETE 60
           S + +   + +R+++R A+ RE++K KE+ R+ +++  + K +E  +D      + R+T 
Sbjct: 79  SPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTV 138

Query: 61  ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVD 120
           A    +G       +        +SVS        +  + G   R R ++          
Sbjct: 139 AHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYR---------- 188

Query: 121 FLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELT 180
                 + Y      PL     +E+ E       +  +D++   +   +E +E   +E +
Sbjct: 189 ---ERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKS 245

Query: 181 -------EEEKQQILHSEEF 193
                  EE  ++  H E F
Sbjct: 246 NSFSDKGEERHKEKRHKEGF 265


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 46/191 (24%), Positives = 89/191 (46%), Gaps = 15/191 (7%)

Query: 6   DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           D   +LERK++R  ++RE++K  R+++ER+++  + ++++E  ++ S   R  RE  +  
Sbjct: 154 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS-- 211

Query: 64  QSIGIS------PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLT--RRRLHKLGVSK 115
             +  S      P PP     +    K V            DL  ++   R+      S 
Sbjct: 212 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 271

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAP 175
                    E     +E +    + +SEE+EE+EE  E + G +SE  ++   +EV E  
Sbjct: 272 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-- 329

Query: 176 PRELTEEEKQQ 186
             E++E+E+++
Sbjct: 330 -EEMSEDEERE 339



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/230 (21%), Positives = 95/230 (41%), Gaps = 5/230 (2%)

Query: 8   KAELERKKQRLAQIREEKKRKEEERKKKEADMQ-QKKEPVQDDSDLDRKRRETEALLQSI 66
           + E+ R+  R  + R E+  ++ ER++K  + Q +++E  + +   + +R+E EA  +  
Sbjct: 141 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVS 200

Query: 67  G---ISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLP 123
                  E        S  S+S   P     +      P+   ++ +  +    Q D   
Sbjct: 201 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISD 259

Query: 124 REVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEE 183
            E  + S E+ +  +   SEE+EE+EE  E +     E E +++++E +E      +EE 
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319

Query: 184 KQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAG 233
            +Q           +   R  E  L    +  FD    E EE + +V  G
Sbjct: 320 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 369



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 38/196 (19%), Positives = 77/196 (39%), Gaps = 19/196 (9%)

Query: 21  IREEKKRKEEERK------KKEADMQQKKEPVQDDSDLDRKRRET--------EALLQSI 66
           ++E+K+RKE+E K      K   D   K++ +++    D     T        E  ++  
Sbjct: 17  LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76

Query: 67  GISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLPREV 126
           G   +   +  P   S K      +   +         + R H+       + D   RE 
Sbjct: 77  GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARRE- 135

Query: 127 VSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQ 186
             + ++ +  +A   S  + +  E +E K  ++ ++  Q K+Q  +E   RE   EE+++
Sbjct: 136 --WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ--REQKERERRAEERRK 191

Query: 187 ILHSEEFLIFFDRTIR 202
              +   +    RT+R
Sbjct: 192 EREARREVSAHHRTMR 207


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 46/191 (24%), Positives = 89/191 (46%), Gaps = 15/191 (7%)

Query: 6   DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           D   +LERK++R  ++RE++K  R+++ER+++  + ++++E  ++ S   R  RE  +  
Sbjct: 164 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS-- 221

Query: 64  QSIGIS------PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLT--RRRLHKLGVSK 115
             +  S      P PP     +    K V            DL  ++   R+      S 
Sbjct: 222 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 281

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAP 175
                    E     +E +    + +SEE+EE+EE  E + G +SE  ++   +EV E  
Sbjct: 282 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-- 339

Query: 176 PRELTEEEKQQ 186
             E++E+E+++
Sbjct: 340 -EEMSEDEERE 349



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/230 (21%), Positives = 95/230 (41%), Gaps = 5/230 (2%)

Query: 8   KAELERKKQRLAQIREEKKRKEEERKKKEADMQ-QKKEPVQDDSDLDRKRRETEALLQSI 66
           + E+ R+  R  + R E+  ++ ER++K  + Q +++E  + +   + +R+E EA  +  
Sbjct: 151 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVS 210

Query: 67  G---ISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLP 123
                  E        S  S+S   P     +      P+   ++ +  +    Q D   
Sbjct: 211 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISD 269

Query: 124 REVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEE 183
            E  + S E+ +  +   SEE+EE+EE  E +     E E +++++E +E      +EE 
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329

Query: 184 KQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAG 233
            +Q           +   R  E  L    +  FD    E EE + +V  G
Sbjct: 330 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 379


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 46/191 (24%), Positives = 89/191 (46%), Gaps = 15/191 (7%)

Query: 6   DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           D   +LERK++R  ++RE++K  R+++ER+++  + ++++E  ++ S   R  RE  +  
Sbjct: 155 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS-- 212

Query: 64  QSIGIS------PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLT--RRRLHKLGVSK 115
             +  S      P PP     +    K V            DL  ++   R+      S 
Sbjct: 213 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 272

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAP 175
                    E     +E +    + +SEE+EE+EE  E + G +SE  ++   +EV E  
Sbjct: 273 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-- 330

Query: 176 PRELTEEEKQQ 186
             E++E+E+++
Sbjct: 331 -EEMSEDEERE 340



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/230 (21%), Positives = 95/230 (41%), Gaps = 5/230 (2%)

Query: 8   KAELERKKQRLAQIREEKKRKEEERKKKEADMQ-QKKEPVQDDSDLDRKRRETEALLQSI 66
           + E+ R+  R  + R E+  ++ ER++K  + Q +++E  + +   + +R+E EA  +  
Sbjct: 142 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVS 201

Query: 67  G---ISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLP 123
                  E        S  S+S   P     +      P+   ++ +  +    Q D   
Sbjct: 202 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISD 260

Query: 124 REVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEE 183
            E  + S E+ +  +   SEE+EE+EE  E +     E E +++++E +E      +EE 
Sbjct: 261 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 320

Query: 184 KQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAG 233
            +Q           +   R  E  L    +  FD    E EE + +V  G
Sbjct: 321 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 370



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 39/197 (19%), Positives = 79/197 (40%), Gaps = 20/197 (10%)

Query: 21  IREEKKRKEEERK------KKEADMQQKKEPVQDDSDLDRKRRET--------EALLQSI 66
           ++E+K+RKE+E K      K   D   K++ +++    D     T        E  ++  
Sbjct: 17  LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76

Query: 67  GISPEPPLVPTPMSPSSK-SVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLPRE 125
           G   +   +  P   S K  V    +   ++        + R H+       + D   RE
Sbjct: 77  GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARRE 136

Query: 126 VVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQ 185
              + ++ +  +A   S  + +  E +E K  ++ ++  Q K+Q  +E   RE   EE++
Sbjct: 137 ---WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ--REQKERERRAEERR 191

Query: 186 QILHSEEFLIFFDRTIR 202
           +   +   +    RT+R
Sbjct: 192 KEREARREVSAHHRTMR 208


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 46/191 (24%), Positives = 89/191 (46%), Gaps = 15/191 (7%)

Query: 6   DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           D   +LERK++R  ++RE++K  R+++ER+++  + ++++E  ++ S   R  RE  +  
Sbjct: 164 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS-- 221

Query: 64  QSIGIS------PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLT--RRRLHKLGVSK 115
             +  S      P PP     +    K V            DL  ++   R+      S 
Sbjct: 222 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 281

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAP 175
                    E     +E +    + +SEE+EE+EE  E + G +SE  ++   +EV E  
Sbjct: 282 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-- 339

Query: 176 PRELTEEEKQQ 186
             E++E+E+++
Sbjct: 340 -EEMSEDEERE 349


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 46/191 (24%), Positives = 89/191 (46%), Gaps = 15/191 (7%)

Query: 6   DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           D   +LERK++R  ++RE++K  R+++ER+++  + ++++E  ++ S   R  RE  +  
Sbjct: 132 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS-- 189

Query: 64  QSIGIS------PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLT--RRRLHKLGVSK 115
             +  S      P PP     +    K V            DL  ++   R+      S 
Sbjct: 190 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 249

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAP 175
                    E     +E +    + +SEE+EE+EE  E + G +SE  ++   +EV E  
Sbjct: 250 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-- 307

Query: 176 PRELTEEEKQQ 186
             E++E+E+++
Sbjct: 308 -EEMSEDEERE 317



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/230 (21%), Positives = 95/230 (41%), Gaps = 5/230 (2%)

Query: 8   KAELERKKQRLAQIREEKKRKEEERKKKEADMQ-QKKEPVQDDSDLDRKRRETEALLQSI 66
           + E+ R+  R  + R E+  ++ ER++K  + Q +++E  + +   + +R+E EA  +  
Sbjct: 119 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVS 178

Query: 67  G---ISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLP 123
                  E        S  S+S   P     +      P+   ++ +  +    Q D   
Sbjct: 179 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISD 237

Query: 124 REVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEE 183
            E  + S E+ +  +   SEE+EE+EE  E +     E E +++++E +E      +EE 
Sbjct: 238 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 297

Query: 184 KQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAG 233
            +Q           +   R  E  L    +  FD    E EE + +V  G
Sbjct: 298 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 347


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 46/191 (24%), Positives = 89/191 (46%), Gaps = 15/191 (7%)

Query: 6   DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           D   +LERK++R  ++RE++K  R+++ER+++  + ++++E  ++ S   R  RE  +  
Sbjct: 121 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS-- 178

Query: 64  QSIGIS------PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLT--RRRLHKLGVSK 115
             +  S      P PP     +    K V            DL  ++   R+      S 
Sbjct: 179 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 238

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAP 175
                    E     +E +    + +SEE+EE+EE  E + G +SE  ++   +EV E  
Sbjct: 239 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-- 296

Query: 176 PRELTEEEKQQ 186
             E++E+E+++
Sbjct: 297 -EEMSEDEERE 306



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/230 (21%), Positives = 95/230 (41%), Gaps = 5/230 (2%)

Query: 8   KAELERKKQRLAQIREEKKRKEEERKKKEADMQ-QKKEPVQDDSDLDRKRRETEALLQSI 66
           + E+ R+  R  + R E+  ++ ER++K  + Q +++E  + +   + +R+E EA  +  
Sbjct: 108 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVS 167

Query: 67  G---ISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLP 123
                  E        S  S+S   P     +      P+   ++ +  +    Q D   
Sbjct: 168 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISD 226

Query: 124 REVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEE 183
            E  + S E+ +  +   SEE+EE+EE  E +     E E +++++E +E      +EE 
Sbjct: 227 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 286

Query: 184 KQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAG 233
            +Q           +   R  E  L    +  FD    E EE + +V  G
Sbjct: 287 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 336


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 46/191 (24%), Positives = 89/191 (46%), Gaps = 15/191 (7%)

Query: 6   DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           D   +LERK++R  ++RE++K  R+++ER+++  + ++++E  ++ S   R  RE  +  
Sbjct: 166 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS-- 223

Query: 64  QSIGIS------PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLT--RRRLHKLGVSK 115
             +  S      P PP     +    K V            DL  ++   R+      S 
Sbjct: 224 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 283

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAP 175
                    E     +E +    + +SEE+EE+EE  E + G +SE  ++   +EV E  
Sbjct: 284 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-- 341

Query: 176 PRELTEEEKQQ 186
             E++E+E+++
Sbjct: 342 -EEMSEDEERE 351



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/230 (21%), Positives = 95/230 (41%), Gaps = 5/230 (2%)

Query: 8   KAELERKKQRLAQIREEKKRKEEERKKKEADMQ-QKKEPVQDDSDLDRKRRETEALLQSI 66
           + E+ R+  R  + R E+  ++ ER++K  + Q +++E  + +   + +R+E EA  +  
Sbjct: 153 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVS 212

Query: 67  G---ISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLP 123
                  E        S  S+S   P     +      P+   ++ +  +    Q D   
Sbjct: 213 AHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISD 271

Query: 124 REVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEE 183
            E  + S E+ +  +   SEE+EE+EE  E +     E E +++++E +E      +EE 
Sbjct: 272 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 331

Query: 184 KQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAG 233
            +Q           +   R  E  L    +  FD    E EE + +V  G
Sbjct: 332 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 381


>gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]
          Length = 1205

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)

Query: 222 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 281
           +L +   D+++ A  S + +++   W  ++    MD       +++A   N     ++P 
Sbjct: 49  DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104

Query: 282 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 336
            +      +V     K T P         V ++    F  NLV  G    +I +WD  + 
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155

Query: 337 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 394
                  TP++  A T P   ++ +    Q  H L + S  G+   W L       E + 
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205

Query: 395 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 452
            V + S  +  +G+A+        V+ SE+  +        +       V E H   +  
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265

Query: 453 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 512
           I   MA        L ++   D  +        + LY    N  + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320

Query: 513 CVDGMGRLDLWNL 525
                GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333


>gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]
          Length = 1220

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)

Query: 222 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 281
           +L +   D+++ A  S + +++   W  ++    MD       +++A   N     ++P 
Sbjct: 49  DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104

Query: 282 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 336
            +      +V     K T P         V ++    F  NLV  G    +I +WD  + 
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155

Query: 337 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 394
                  TP++  A T P   ++ +    Q  H L + S  G+   W L       E + 
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205

Query: 395 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 452
            V + S  +  +G+A+        V+ SE+  +        +       V E H   +  
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265

Query: 453 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 512
           I   MA        L ++   D  +        + LY    N  + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320

Query: 513 CVDGMGRLDLWNL 525
                GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333


>gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
          Length = 1106

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)

Query: 222 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 281
           +L +   D+++ A  S + +++   W  ++    MD       +++A   N     ++P 
Sbjct: 49  DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104

Query: 282 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 336
            +      +V     K T P         V ++    F  NLV  G    +I +WD  + 
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155

Query: 337 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 394
                  TP++  A T P   ++ +    Q  H L + S  G+   W L       E + 
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205

Query: 395 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 452
            V + S  +  +G+A+        V+ SE+  +        +       V E H   +  
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265

Query: 453 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 512
           I   MA        L ++   D  +        + LY    N  + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320

Query: 513 CVDGMGRLDLWNL 525
                GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333


>gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]
          Length = 1181

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)

Query: 222 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 281
           +L +   D+++ A  S + +++   W  ++    MD       +++A   N     ++P 
Sbjct: 49  DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104

Query: 282 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 336
            +      +V     K T P         V ++    F  NLV  G    +I +WD  + 
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155

Query: 337 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 394
                  TP++  A T P   ++ +    Q  H L + S  G+   W L       E + 
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205

Query: 395 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 452
            V + S  +  +G+A+        V+ SE+  +        +       V E H   +  
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265

Query: 453 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 512
           I   MA        L ++   D  +        + LY    N  + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320

Query: 513 CVDGMGRLDLWNL 525
                GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333


>gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]
          Length = 1220

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)

Query: 222 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 281
           +L +   D+++ A  S + +++   W  ++    MD       +++A   N     ++P 
Sbjct: 49  DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104

Query: 282 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 336
            +      +V     K T P         V ++    F  NLV  G    +I +WD  + 
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155

Query: 337 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 394
                  TP++  A T P   ++ +    Q  H L + S  G+   W L       E + 
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205

Query: 395 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 452
            V + S  +  +G+A+        V+ SE+  +        +       V E H   +  
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265

Query: 453 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 512
           I   MA        L ++   D  +        + LY    N  + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320

Query: 513 CVDGMGRLDLWNL 525
                GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333


>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
          Length = 425

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 57/243 (23%), Positives = 104/243 (42%), Gaps = 25/243 (10%)

Query: 315 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 370
           +P+++   T S  ++++D   H   P         L    H    Y ++     + H L+
Sbjct: 135 NPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGH-LL 193

Query: 371 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFV--------VGS 422
           + S D  +C W  D+ + P+E  ++V  K+     TG +    DV   +        V  
Sbjct: 194 SASDDHTVCLW--DINAGPKEG-KIVDAKA---IFTGHSAVVEDVAWHLLHESLFGSVAD 247

Query: 423 EEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTT 482
           ++  +    R  + +    + + H   V   NC ++  P     +  T S D TV LW  
Sbjct: 248 DQKLMIWDTRSNTTSKPSHLVDAHTAEV---NC-LSFNPYS-EFILATGSADKTVALWDL 302

Query: 483 KHNK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGA 541
           ++ K  L++FE + D ++ V WSP +  + A      RL++W+L+   E  +A  A +G 
Sbjct: 303 RNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGP 362

Query: 542 SAL 544
             L
Sbjct: 363 PEL 365


>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
          Length = 323

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 437 AGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNAD 496
           AG  +V++ H   V  ++     G      L V+ S+D TVKLW     K L +F  +  
Sbjct: 101 AGPLQVYKEHAQEVYSVDWSQTRG----EQLVVSGSWDQTVKLWDPTVGKSLCTFRGHES 156

Query: 497 YVYDVMWSPVHPALFACVDGMGRLDLWNL 525
            +Y  +WSP  P  FA   G   L +W++
Sbjct: 157 IIYSTIWSPHIPGCFASASGDQTLRIWDV 185



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 41/168 (24%), Positives = 61/168 (36%), Gaps = 39/168 (23%)

Query: 419 VVGSEEGTVYTACRHGSKAGIGEVFEG--------HQGPVTGINCHMAVGPIDFSHLFVT 470
           V G     + T  RHG  A       G        H G + G    + + P D + L + 
Sbjct: 4   VCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYG-IAGCGTLLILDP-DEAGLRLF 61

Query: 471 SSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTE 530
            SFDW                    D ++DV WS  +  +     G G L LW    DT 
Sbjct: 62  RSFDWN-------------------DGLFDVTWSENNEHVLITCSGDGSLQLW----DTA 98

Query: 531 VPTASVAI--EGASALNRVRWAQA-GKEVAVG---DSEGRIWVYDVGE 572
                + +  E A  +  V W+Q  G+++ V    D   ++W   VG+
Sbjct: 99  KAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGK 146


>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
           sapiens]
          Length = 390

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)

Query: 315 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 370
           +P ++   T S  ++++D   H   P         L    H    Y ++     + H L+
Sbjct: 101 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 159

Query: 371 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 430
           + S D  +C W  D+ + P+E   +          TG      DV+  ++     +++ +
Sbjct: 160 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 210

Query: 431 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 484
                K  I +    +   P   ++ H A V  + F+     +  T S D TV LW  ++
Sbjct: 211 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 270

Query: 485 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 543
            K  L+SFE + D ++ V WSP +  + A      RL++W+L+   E  +   A +G   
Sbjct: 271 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 330

Query: 544 L 544
           L
Sbjct: 331 L 331


>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
           sapiens]
          Length = 424

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)

Query: 315 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 370
           +P ++   T S  ++++D   H   P         L    H    Y ++     + H L+
Sbjct: 135 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 193

Query: 371 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 430
           + S D  +C W  D+ + P+E   +          TG      DV+  ++     +++ +
Sbjct: 194 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 244

Query: 431 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 484
                K  I +    +   P   ++ H A V  + F+     +  T S D TV LW  ++
Sbjct: 245 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 304

Query: 485 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 543
            K  L+SFE + D ++ V WSP +  + A      RL++W+L+   E  +   A +G   
Sbjct: 305 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 364

Query: 544 L 544
           L
Sbjct: 365 L 365


>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
           sapiens]
          Length = 425

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)

Query: 315 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 370
           +P ++   T S  ++++D   H   P         L    H    Y ++     + H L+
Sbjct: 136 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 194

Query: 371 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 430
           + S D  +C W  D+ + P+E   +          TG      DV+  ++     +++ +
Sbjct: 195 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 245

Query: 431 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 484
                K  I +    +   P   ++ H A V  + F+     +  T S D TV LW  ++
Sbjct: 246 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 305

Query: 485 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 543
            K  L+SFE + D ++ V WSP +  + A      RL++W+L+   E  +   A +G   
Sbjct: 306 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 365

Query: 544 L 544
           L
Sbjct: 366 L 366


>gi|161702986 ezrin [Homo sapiens]
          Length = 586

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 9/174 (5%)

Query: 4   KSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           K+  + E  +K+    Q+  EKKR+E   ++KE  M++K+E +    D + K ++ E  L
Sbjct: 306 KAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAEREL 365

Query: 64  QSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL-TRRRLHKLGVSKVTQVDFL 122
                      +   +    +      EA   ++  +  L  +  L +  V ++   + L
Sbjct: 366 SE--------QIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417

Query: 123 PREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPP 176
             E+  Y+ +        + +EDE +E    +K  QD  ++ +++   V  APP
Sbjct: 418 AAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPP 471



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 32/178 (17%), Positives = 78/178 (43%), Gaps = 23/178 (12%)

Query: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
           +  +  L AEL     ++A + E ++RKE+E +    + Q + +  QDD        +T+
Sbjct: 411 IKSQEQLAAELAEYTAKIALLEEARRRKEDEVE----EWQHRAKEAQDD------LVKTK 460

Query: 61  ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRR-----RLHKLGVSK 115
             L  +  +P PP  P     S     +  + G++ +G    L+       R  +  +++
Sbjct: 461 EELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITE 520

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKE 173
             + + + R++++ S E         S+  +E++      +  ++  + +DK + +++
Sbjct: 521 AEKNERVQRQLLTLSSEL--------SQARDENKRTHNDIIHNENMRQGRDKYKTLRQ 570


>gi|21614499 ezrin [Homo sapiens]
          Length = 586

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 9/174 (5%)

Query: 4   KSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
           K+  + E  +K+    Q+  EKKR+E   ++KE  M++K+E +    D + K ++ E  L
Sbjct: 306 KAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAEREL 365

Query: 64  QSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL-TRRRLHKLGVSKVTQVDFL 122
                      +   +    +      EA   ++  +  L  +  L +  V ++   + L
Sbjct: 366 SE--------QIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417

Query: 123 PREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPP 176
             E+  Y+ +        + +EDE +E    +K  QD  ++ +++   V  APP
Sbjct: 418 AAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPP 471



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 32/178 (17%), Positives = 78/178 (43%), Gaps = 23/178 (12%)

Query: 1   MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
           +  +  L AEL     ++A + E ++RKE+E +    + Q + +  QDD        +T+
Sbjct: 411 IKSQEQLAAELAEYTAKIALLEEARRRKEDEVE----EWQHRAKEAQDD------LVKTK 460

Query: 61  ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRR-----RLHKLGVSK 115
             L  +  +P PP  P     S     +  + G++ +G    L+       R  +  +++
Sbjct: 461 EELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITE 520

Query: 116 VTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKE 173
             + + + R++++ S E         S+  +E++      +  ++  + +DK + +++
Sbjct: 521 AEKNERVQRQLLTLSSEL--------SQARDENKRTHNDIIHNENMRQGRDKYKTLRQ 570


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 45/181 (24%), Positives = 81/181 (44%), Gaps = 19/181 (10%)

Query: 393 MELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTG 452
           ++++Y  S PV   G +F + D N  +  SE+GTV           +G  ++GH  PV  
Sbjct: 536 LKILYGHSGPVY--GASF-SPDRNYLLSSSEDGTVRLWSLQTFTCLVG--YKGHNYPVWD 590

Query: 453 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 512
                      + + FV+   D   +LW T H +PL  F   A ++ DV  +  HP    
Sbjct: 591 TQFS------PYGYYFVSGGHDRVARLWATDHYQPLRIF---AGHLADVNCTRFHPNSNY 641

Query: 513 CVDGMG--RLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDV 570
              G     + LW++ N   V    +       ++ + ++  G+ +A G ++GR+ ++D+
Sbjct: 642 VATGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI 698

Query: 571 G 571
           G
Sbjct: 699 G 699


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,051,864
Number of Sequences: 37866
Number of extensions: 1268646
Number of successful extensions: 20096
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 413
Number of HSP's successfully gapped in prelim test: 666
Number of HSP's that attempted gapping in prelim test: 10265
Number of HSP's gapped (non-prelim): 6955
length of query: 608
length of database: 18,247,518
effective HSP length: 108
effective length of query: 500
effective length of database: 14,157,990
effective search space: 7078995000
effective search space used: 7078995000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.