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Search of human proteins with 207113122
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|207113122 dynein, cytoplasmic 1, intermediate chain 1
isoform b [Homo sapiens]
(628 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform... 1280 0.0
gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a... 1269 0.0
gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform... 1228 0.0
gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa... 1007 0.0
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens] 115 9e-26
gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens] 104 3e-22
gi|66267730 WD repeat domain 34 [Homo sapiens] 99 9e-21
gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo ... 94 3e-19
gi|217272887 WD repeat domain 63 [Homo sapiens] 57 4e-08
gi|155030242 WD repeat domain 60 [Homo sapiens] 55 1e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 52 1e-06
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 52 1e-06
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 52 1e-06
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 52 1e-06
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 52 1e-06
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 52 1e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 52 1e-06
gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] 51 3e-06
gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 51 3e-06
gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] 51 3e-06
gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 51 3e-06
gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 51 3e-06
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 50 5e-06
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 49 1e-05
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 49 1e-05
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 49 1e-05
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 49 1e-05
gi|148746195 trichohyalin [Homo sapiens] 49 2e-05
gi|21071067 TBP-associated factor 5 [Homo sapiens] 48 3e-05
gi|4505999 protein phosphatase 1G [Homo sapiens] 45 2e-04
>gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform b
[Homo sapiens]
Length = 628
Score = 1280 bits (3312), Expect = 0.0
Identities = 628/628 (100%), Positives = 628/628 (100%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
Query: 61 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 120
ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS
Sbjct: 61 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 120
Query: 121 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 180
DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS
Sbjct: 121 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 180
Query: 181 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 240
ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG
Sbjct: 181 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 240
Query: 241 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 300
RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP
Sbjct: 241 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 300
Query: 301 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 360
DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP
Sbjct: 301 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 360
Query: 361 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 420
VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS
Sbjct: 361 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 420
Query: 421 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 480
KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG
Sbjct: 421 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 480
Query: 481 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 540
PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL
Sbjct: 481 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 540
Query: 541 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 600
DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE
Sbjct: 541 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 600
Query: 601 WTRFARTLVEIRANRADSEEEGTVELSA 628
WTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 601 WTRFARTLVEIRANRADSEEEGTVELSA 628
>gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a
[Homo sapiens]
Length = 645
Score = 1269 bits (3284), Expect = 0.0
Identities = 628/645 (97%), Positives = 628/645 (97%), Gaps = 17/645 (2%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
Query: 61 ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL 103
ALLQSIGISPEPPLV PTPMSPSSKSVSTPSEAGSQDSGDLGPL
Sbjct: 61 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 120
Query: 104 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 163
TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE
Sbjct: 121 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 180
Query: 164 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 223
EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV
Sbjct: 181 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 240
Query: 224 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 283
IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP
Sbjct: 241 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 300
Query: 284 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 343
ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT
Sbjct: 301 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 360
Query: 344 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 403
YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL
Sbjct: 361 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 420
Query: 404 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 463
DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF
Sbjct: 421 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 480
Query: 464 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 523
EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW
Sbjct: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 540
Query: 524 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 583
SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG
Sbjct: 541 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 600
Query: 584 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 628
RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 601 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645
>gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform c
[Homo sapiens]
Length = 608
Score = 1228 bits (3177), Expect = 0.0
Identities = 608/628 (96%), Positives = 608/628 (96%), Gaps = 20/628 (3%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
Query: 61 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 120
ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTR
Sbjct: 61 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTR--------------- 105
Query: 121 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 180
RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS
Sbjct: 106 -----RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 160
Query: 181 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 240
ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG
Sbjct: 161 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 220
Query: 241 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 300
RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP
Sbjct: 221 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 280
Query: 301 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 360
DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP
Sbjct: 281 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 340
Query: 361 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 420
VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS
Sbjct: 341 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 400
Query: 421 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 480
KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG
Sbjct: 401 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 460
Query: 481 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 540
PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL
Sbjct: 461 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 520
Query: 541 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 600
DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE
Sbjct: 521 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 580
Query: 601 WTRFARTLVEIRANRADSEEEGTVELSA 628
WTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 581 WTRFARTLVEIRANRADSEEEGTVELSA 608
>gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
sapiens]
Length = 638
Score = 1007 bits (2604), Expect = 0.0
Identities = 490/640 (76%), Positives = 558/640 (87%), Gaps = 14/640 (2%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKE---PVQDDSDLDRKRR 57
MSDKS+LKAELERKKQRLAQIREEKKRKEEERKKKE D QKKE PVQ++SDL++KRR
Sbjct: 1 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETD--QKKEAVAPVQEESDLEKKRR 58
Query: 58 ETEALLQSIGISPEPPLV------PTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDT 111
E EALLQS+G++PE P+V P PMSPSSKSVSTPSEAGSQDSGD +RTL WDT
Sbjct: 59 EAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDT 118
Query: 112 DPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEM 171
DPSVLQL SDS+LGR KLG++K+TQVDF PRE+V+Y+KETQTP+ E++EED+++
Sbjct: 119 DPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDV 178
Query: 172 VESKVGQDSELENQDKKQEVKE--APPRELTEEEKQQILHSEEFLIFFDRTIRVIERALA 229
V K + E E KK E + APP ELTEEEKQQILHSEEFL FFD + R++ERAL+
Sbjct: 179 VAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALS 238
Query: 230 EDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVAS 289
E +IFFDYSGR+LE+K+G++QAGA LS NRQF+DE WSKHRVV+C+DWS QYPEL+VAS
Sbjct: 239 EQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVAS 298
Query: 290 YNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIV 349
YNNNEDAPHEPDGVALVWNMK+KKTTPEYVFHCQS+VMS FA+FHPNLVVGGTYSGQIV
Sbjct: 299 YNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIV 358
Query: 350 LWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTP 409
LWDNRS++RTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLI++STDGK+CSWSLDMLS P
Sbjct: 359 LWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHP 418
Query: 410 QESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGP 469
Q+SMELV+ +SK VAVT M+FP GDVNNFVVGSEEG+VYTACRHGSKAGI E+FEGHQGP
Sbjct: 419 QDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGP 478
Query: 470 VTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPA 529
+TGI+CH AVG +DFSHLFVTSSFDWTVKLWTTK+NKPLYSFEDNADYVYDVMWSP HPA
Sbjct: 479 ITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPA 538
Query: 530 LFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYD 589
LFACVDGMGRLDLWNLNNDTEVPTAS+++EG ALNRVRW +G+E+AVGDSEG+I +YD
Sbjct: 539 LFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYD 598
Query: 590 VGE-LAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 628
VGE +AVP NDEW RF RTL EI ANRAD+EEE + A
Sbjct: 599 VGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638
>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
Length = 848
Score = 115 bits (289), Expect = 9e-26
Identities = 115/483 (23%), Positives = 206/483 (42%), Gaps = 72/483 (14%)
Query: 166 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEF---LIFFDRTI- 221
++D+ + S ++SE + + V A E E+ IL S++F L F +R +
Sbjct: 353 DQDQRLPGSTTEKNSETSSLMDIENVILAKIHEDEEDHSDAILKSDKFHQDLFFMERVLM 412
Query: 222 -RVIERALA--------------EDSDIFFDYSGRELEE---KDGDVQAGANLSFNRQFY 263
+ + LA E D+ E+EE K+ + + A S
Sbjct: 413 ENIFQPKLAAYRQLPVLKEPEPEEPEDVLESAKHEEVEEESKKEEEEEIHAEESTIPANL 472
Query: 264 DEHWS------KHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPE 317
+ WS K V+ + W+ P+L+ Y + + G+A W++K PE
Sbjct: 473 ERLWSFSCDLTKGLNVSSLAWNKTNPDLLAVGYGHF-GFKEQKRGLACCWSIK-NPMWPE 530
Query: 318 YVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYC 377
++ V +V F+ PNL+ G ++G I +++ RS+ PV + S H PV+
Sbjct: 531 RIYQSPYGVTAVDFSIGAPNLLAVGYHNGTIAIYNVRSNSNVPVLDSSESPQKHLGPVWQ 590
Query: 378 VNVV-------GTQNAHNLITVSTDGKMCSWSL-------DML-------------STPQ 410
+ + G L+++S DG++ W + D++ +
Sbjct: 591 LQWIEQDRGTTGDGKREILVSISADGRISKWVIRKGLDCYDLMRLKRTTAASNKKGGEKE 650
Query: 411 ESMELVYNKSKPVAVTGM--AFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQG 468
+ E + ++ P GM AF D N ++ G+EEG ++ C + + GH+G
Sbjct: 651 KKDEALISRQAP----GMCFAFHPKDTNIYLAGTEEGHIHK-CSCSYNEQYLDTYRGHKG 705
Query: 469 PVTGINCHMAVGPIDFSH-LFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVH 527
PV + + F H +F++ S DW V +W ++ KP SF VYDV WSP
Sbjct: 706 PVYKVTWN------PFCHDVFLSCSADWGVIIWQQENVKPSLSFYPATSVVYDVAWSPKS 759
Query: 528 PALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWV 587
+FA + R+++W+L+ T P + +A+ + VGDS+G++ V
Sbjct: 760 SYIFAAAN-ENRVEIWDLHISTLDPLIVNTANPGIKFTTILFAKQTDCLLVGDSDGQVSV 818
Query: 588 YDV 590
Y++
Sbjct: 819 YEL 821
>gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens]
Length = 699
Score = 104 bits (259), Expect = 3e-22
Identities = 130/545 (23%), Positives = 230/545 (42%), Gaps = 71/545 (13%)
Query: 92 AGSQDSGDLGPLTRTLQWDTDPSVLQL----QSDSELGRRLHKLGVSKV----------- 136
AGSQ+S + T L+ D +P L+ Q+D K+ ++
Sbjct: 129 AGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTPKQPKERKL 188
Query: 137 -TQVDFLPREVVSYSK-------ETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKK 188
Q +F R +Y+ +T+ P T+ S + E+ ++ V ELE Q+K
Sbjct: 189 TNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQ-WEIYDAYV---EELEKQEKT 244
Query: 189 QEVKEAPP-----------RELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDS--DIF 235
+E ++A R+LT E Q + LI + +++ER + +++ DI
Sbjct: 245 KEKEKAKTPVAKKSGKMAMRKLTSMESQT-----DDLIKLSQAAKIMERMVNQNTYDDIA 299
Query: 236 FDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNED 295
D+ + + Q G L + D+ +K VT + W+ +Y +L Y + D
Sbjct: 300 QDFKYYDDAADEYRDQVGTLLPLWKFQNDK--AKRLSVTALCWNPKYRDLFAVGYGSY-D 356
Query: 296 APHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRS 355
+ G+ L++++K + PEY+F S VM + HP LV G Y G + +++ +
Sbjct: 357 FMKQSRGMLLLYSLK-NPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKK 415
Query: 356 HRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNL--ITVSTDGKMCSWSL--------DM 405
P + + H+ PV+ V NL +VS+DG++ SW+L D+
Sbjct: 416 PHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDV 475
Query: 406 LSTPQESMELVYNKS---KPVAV-TGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGE 461
+ E + PV T F F+VG+EEG +Y C + +
Sbjct: 476 IKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIY-KCSKSYSSQFLD 534
Query: 462 VFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDV 521
++ H V ++ + + +F++ S DWTVK+W P++ ++ N+ V DV
Sbjct: 535 TYDAHNMSVDTVSWNPY-----HTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNS-AVGDV 588
Query: 522 MWSPVHPALFACVDGMGRLDLWNLN-NDTEVPTASVAIEGASALNRVRWAQAGKEVAVGD 580
W+P +FA V G+ +++L N E + L V++ + VGD
Sbjct: 589 AWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGD 648
Query: 581 SEGRI 585
G I
Sbjct: 649 DRGHI 653
>gi|66267730 WD repeat domain 34 [Homo sapiens]
Length = 536
Score = 99.4 bits (246), Expect = 9e-21
Identities = 80/320 (25%), Positives = 146/320 (45%), Gaps = 41/320 (12%)
Query: 307 WNMKFKKTTPEY---VFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQR 363
WN+ + P+ V S+V+ + F P+ V GG YSG++++WD + R
Sbjct: 198 WNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWR 257
Query: 364 TPLSAAAHTHPVYCVNVV---GTQNAHNLITVSTDGKMCSW--------------SLDML 406
T L+ HT PV V + G + +++V+TDGK+ W +L M
Sbjct: 258 TGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQ 317
Query: 407 STPQESMELVYNKSKP-VAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV--- 462
P+ + + + + V T +AF + D F++G+E G +A + +
Sbjct: 318 QLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSS 377
Query: 463 ----------FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFE 512
F H GP+ ++C P +LF+++ D V L++ PL S +
Sbjct: 378 VPLRAPAQFTFSPHGGPIYSVSC----SPFH-RNLFLSAGTDGHVHLYSMLQAPPLTSLQ 432
Query: 513 DNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASV-AIEGASALNRVRW-A 570
+ Y++ V WSPV P +FA G G + L++L ++ PT + + S + + + +
Sbjct: 433 LSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNS 492
Query: 571 QAGKEVAVGDSEGRIWVYDV 590
Q + +A GD++G + V+ +
Sbjct: 493 QQTQLLAAGDAQGTVKVWQL 512
>gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
sapiens]
Length = 605
Score = 94.4 bits (233), Expect = 3e-19
Identities = 104/488 (21%), Positives = 201/488 (41%), Gaps = 37/488 (7%)
Query: 122 SELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATH-QSEEDEEDEEMVESKVGQDS 180
SE G++ + +D +P ++ + P+ T Q + E + ++
Sbjct: 12 SEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEHEANSERFEMET 71
Query: 181 ELENQDKKQEVKEAPPREL--TEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDI---- 234
N + K+ P EL T ++++ E ++ + ++E + +++ I
Sbjct: 72 RGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYE 131
Query: 235 --FFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYN- 291
F D E+ E+D + F D K R T + W + +Y+
Sbjct: 132 EYFNDEEAMEVMEEDPSAKT------INVFRDPQEIK-RAATHLSWHPDGNRKLAVAYSC 184
Query: 292 -NNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVL 350
+ + AP + +W+++ PE S ++++ F ++++GG Y+GQI
Sbjct: 185 LDFQRAPVGMSSDSYIWDLE-NPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIAC 243
Query: 351 WDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQ 410
WD R + + V ++H PVY + ++ + STDG++ W + +S P
Sbjct: 244 WDTR--KGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPT 301
Query: 411 ESMELVYNKSKPV----AVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV---F 463
E + L K + + + F + F+VG+E+G V + C +K ++ F
Sbjct: 302 EVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVIS-CNRKAKTSAEKIVCTF 360
Query: 464 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFED-NADYVYDVM 522
GH GP+ + + + F+T DWT ++W+ + + + Y+ D
Sbjct: 361 PGHHGPIYALQRNPF-----YPKNFLTVG-DWTARIWSEDSRESSIMWTKYHMAYLTDAA 414
Query: 523 WSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSE 582
WSPV P +F G LD+W+ + PT S+ + AL +R G +A G
Sbjct: 415 WSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKV-CDEALFCLRVQDNGCLIACGSQL 473
Query: 583 GRIWVYDV 590
G + +V
Sbjct: 474 GTTTLLEV 481
>gi|217272887 WD repeat domain 63 [Homo sapiens]
Length = 891
Score = 57.4 bits (137), Expect = 4e-08
Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 21/199 (10%)
Query: 176 VGQDSELENQDKKQEVKEAP----PRELTEEEKQQILHSEEFLIFFDRTIRVIERALAED 231
+ Q ++ Q K K A PRE +EEEK+ + S+ + F + +E AL ++
Sbjct: 235 IPQIKDISTQTKWTYPKNATTQYYPREFSEEEKETLKQSKPLVDFLNNASISVEIALQQN 294
Query: 232 S--DIFFDYSGRELEEKDGDV--QAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMV 287
+ F D + L E++G + +L + F D H +++TC+ W L+
Sbjct: 295 EIMNTFID-DWKYLAEEEGTFGDKTDTHLKEYQSFTDLHSPTEKMITCVSWHPTIYGLIA 353
Query: 288 ASYN---NNEDAPH-------EPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPN 337
S + ED H +P + L W+ P+ + + F PN
Sbjct: 354 VSVAVRLSFEDRVHFSGKLLLQPS-LILFWSFS-DPIHPQLMLESPDDIFCFKFCPSDPN 411
Query: 338 LVVGGTYSGQIVLWDNRSH 356
++ GG +GQIV+WD +H
Sbjct: 412 IIAGGCINGQIVMWDITAH 430
Score = 30.0 bits (66), Expect = 6.7
Identities = 12/32 (37%), Positives = 22/32 (68%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKK 43
ER+ + L + + KK +E+E+K+ E +M +KK
Sbjct: 812 EREVKHLEYVEQRKKIREQEKKEMELEMAKKK 843
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 55.5 bits (132), Expect = 1e-07
Identities = 70/350 (20%), Positives = 130/350 (37%), Gaps = 80/350 (22%)
Query: 303 VALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRS------- 355
V VW++ ++ + P+ V C+S V C + L+ GT G +V+WD R
Sbjct: 677 VLCVWDI-WQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGSVVVWDLREDSRLHYS 735
Query: 356 ------------------------HRRTPVQRT-PLSAAAHTHPVYCVNVVGTQN----- 385
+ R+P+Q P+S + H + ++ TQ
Sbjct: 736 VTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQSFVLSPFSTQEEMSGL 795
Query: 386 AHNLITVSTDGKMCSWSL-------------DMLSTPQESMELVYNKSKPVA-------- 424
+ ++ ++ G + W + D+ P ++LV++ +
Sbjct: 796 SFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVHSALIQLGDSLSHKGN 855
Query: 425 -------VTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHM 477
+ F D N+F++G++ G + R + ++F+ Q + +
Sbjct: 856 EFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVA-PKLFKPQQHGIRPVK--- 911
Query: 478 AVGPIDFSH----LFVTSSFDWTVKLWTTKHNKPLYSFEDNADY--VYDVMWSPVHPALF 531
V IDFS +F+ D +++L PL ++ + D V + WSP PA+F
Sbjct: 912 -VNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGLQWSPTRPAVF 970
Query: 532 ACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDS 581
D + +W+L P VA + S V A G+ G S
Sbjct: 971 LVQDDTSNIYIWDLLQSDLGP---VAKQQVSPNRLVAMAAVGEPEKAGGS 1017
Score = 33.5 bits (75), Expect = 0.61
Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 22 REEKKRKEEE-RKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISP 70
+EE+K +E++ RK+ E D+ + KEP D D D + R+ A + + SP
Sbjct: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESP 80
Score = 32.3 bits (72), Expect = 1.4
Identities = 48/214 (22%), Positives = 87/214 (40%), Gaps = 20/214 (9%)
Query: 2 SDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQK-KEPVQDDSDLDRKRRETE 60
S + + + +R+++R A+ RE++K KE+ R+ +++ + K +E +D + R+T
Sbjct: 79 SPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTV 138
Query: 61 ALLQSIGISPEPPLVPTPMSPSSKSVS--------TPSEAGSQDSGDLGPLTRTLQW-DT 111
A +G + +SVS SE G +D + R LQ+ D+
Sbjct: 139 AHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDR-ERRYRERKLQYGDS 197
Query: 112 DPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVS-------YSKETQTPLATHQSEE 164
+ L+ E G R H+ + D RE S YSKE + E
Sbjct: 198 KDNPLKYWLYKEEGERRHR--KPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEER 255
Query: 165 DEEDEEMVESKVGQDSELENQDKKQEVKEAPPRE 198
+E + N D+K++ + PR+
Sbjct: 256 HKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRK 289
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEA-L 62
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE +
Sbjct: 154 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 213
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
+++ S PP P E ++ L S LQ SDS
Sbjct: 214 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL-------------SDLQDISDS 260
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
E R+ S E +E + + +SEE+EE+EE E + G +SE
Sbjct: 261 E--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
++ +EV E E++E+E+++
Sbjct: 319 ASEQSAEEVSE---EEMSEDEERE 339
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEA-L 62
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE +
Sbjct: 164 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 223
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
+++ S PP P E ++ L S LQ SDS
Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL-------------SDLQDISDS 270
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
E R+ S E +E + + +SEE+EE+EE E + G +SE
Sbjct: 271 E--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
++ +EV E E++E+E+++
Sbjct: 329 ASEQSAEEVSE---EEMSEDEERE 349
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEA-L 62
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE +
Sbjct: 155 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 214
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
+++ S PP P E ++ L S LQ SDS
Sbjct: 215 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL-------------SDLQDISDS 261
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
E R+ S E +E + + +SEE+EE+EE E + G +SE
Sbjct: 262 E--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 319
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
++ +EV E E++E+E+++
Sbjct: 320 ASEQSAEEVSE---EEMSEDEERE 340
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEA-L 62
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE +
Sbjct: 164 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 223
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
+++ S PP P E ++ L S LQ SDS
Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL-------------SDLQDISDS 270
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
E R+ S E +E + + +SEE+EE+EE E + G +SE
Sbjct: 271 E--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
++ +EV E E++E+E+++
Sbjct: 329 ASEQSAEEVSE---EEMSEDEERE 349
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEA-L 62
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE +
Sbjct: 132 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 191
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
+++ S PP P E ++ L S LQ SDS
Sbjct: 192 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL-------------SDLQDISDS 238
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
E R+ S E +E + + +SEE+EE+EE E + G +SE
Sbjct: 239 E--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
++ +EV E E++E+E+++
Sbjct: 297 ASEQSAEEVSE---EEMSEDEERE 317
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEA-L 62
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE +
Sbjct: 121 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 180
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
+++ S PP P E ++ L S LQ SDS
Sbjct: 181 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL-------------SDLQDISDS 227
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
E R+ S E +E + + +SEE+EE+EE E + G +SE
Sbjct: 228 E--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 285
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
++ +EV E E++E+E+++
Sbjct: 286 ASEQSAEEVSE---EEMSEDEERE 306
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEA-L 62
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE +
Sbjct: 166 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 225
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
+++ S PP P E ++ L S LQ SDS
Sbjct: 226 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL-------------SDLQDISDS 272
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
E R+ S E +E + + +SEE+EE+EE E + G +SE
Sbjct: 273 E--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 330
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
++ +EV E E++E+E+++
Sbjct: 331 ASEQSAEEVSE---EEMSEDEERE 351
>gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]
Length = 1205
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 242 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 301
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 302 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 356
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 357 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 414
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 415 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 472
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 473 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 532
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 533 CVDGMGRLDLWNL 545
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 242 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 301
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 302 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 356
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 357 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 414
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 415 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 472
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 473 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 532
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 533 CVDGMGRLDLWNL 545
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
Length = 1106
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 242 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 301
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 302 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 356
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 357 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 414
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 415 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 472
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 473 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 532
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 533 CVDGMGRLDLWNL 545
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]
Length = 1181
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 242 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 301
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 302 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 356
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 357 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 414
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 415 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 472
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 473 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 532
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 533 CVDGMGRLDLWNL 545
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 242 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 301
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 302 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 356
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 357 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 414
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 415 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 472
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 473 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 532
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 533 CVDGMGRLDLWNL 545
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 50.4 bits (119), Expect = 5e-06
Identities = 57/243 (23%), Positives = 104/243 (42%), Gaps = 25/243 (10%)
Query: 335 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 390
+P+++ T S ++++D H P L H Y ++ + H L+
Sbjct: 135 NPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGH-LL 193
Query: 391 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFV--------VGS 442
+ S D +C W D+ + P+E ++V K+ TG + DV + V
Sbjct: 194 SASDDHTVCLW--DINAGPKEG-KIVDAKA---IFTGHSAVVEDVAWHLLHESLFGSVAD 247
Query: 443 EEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTT 502
++ + R + + + + H V NC ++ P + T S D TV LW
Sbjct: 248 DQKLMIWDTRSNTTSKPSHLVDAHTAEV---NC-LSFNPYS-EFILATGSADKTVALWDL 302
Query: 503 KHNK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGA 561
++ K L++FE + D ++ V WSP + + A RL++W+L+ E +A A +G
Sbjct: 303 RNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGP 362
Query: 562 SAL 564
L
Sbjct: 363 PEL 365
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 457 AGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNAD 516
AG +V++ H V ++ G L V+ S+D TVKLW K L +F +
Sbjct: 101 AGPLQVYKEHAQEVYSVDWSQTRG----EQLVVSGSWDQTVKLWDPTVGKSLCTFRGHES 156
Query: 517 YVYDVMWSPVHPALFACVDGMGRLDLWNL 545
+Y +WSP P FA G L +W++
Sbjct: 157 IIYSTIWSPHIPGCFASASGDQTLRIWDV 185
Score = 30.8 bits (68), Expect = 3.9
Identities = 41/168 (24%), Positives = 61/168 (36%), Gaps = 39/168 (23%)
Query: 439 VVGSEEGTVYTACRHGSKAGIGEVFEG--------HQGPVTGINCHMAVGPIDFSHLFVT 490
V G + T RHG A G H G + G + + P D + L +
Sbjct: 4 VCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYG-IAGCGTLLILDP-DEAGLRLF 61
Query: 491 SSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTE 550
SFDW D ++DV WS + + G G L LW DT
Sbjct: 62 RSFDWN-------------------DGLFDVTWSENNEHVLITCSGDGSLQLW----DTA 98
Query: 551 VPTASVAI--EGASALNRVRWAQA-GKEVAVG---DSEGRIWVYDVGE 592
+ + E A + V W+Q G+++ V D ++W VG+
Sbjct: 99 KAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGK 146
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)
Query: 335 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 390
+P ++ T S ++++D H P L H Y ++ + H L+
Sbjct: 101 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 159
Query: 391 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 450
+ S D +C W D+ + P+E + TG DV+ ++ +++ +
Sbjct: 160 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 210
Query: 451 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 504
K I + + P ++ H A V + F+ + T S D TV LW ++
Sbjct: 211 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 270
Query: 505 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 563
K L+SFE + D ++ V WSP + + A RL++W+L+ E + A +G
Sbjct: 271 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 330
Query: 564 L 564
L
Sbjct: 331 L 331
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)
Query: 335 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 390
+P ++ T S ++++D H P L H Y ++ + H L+
Sbjct: 135 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 193
Query: 391 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 450
+ S D +C W D+ + P+E + TG DV+ ++ +++ +
Sbjct: 194 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 244
Query: 451 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 504
K I + + P ++ H A V + F+ + T S D TV LW ++
Sbjct: 245 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 304
Query: 505 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 563
K L+SFE + D ++ V WSP + + A RL++W+L+ E + A +G
Sbjct: 305 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 364
Query: 564 L 564
L
Sbjct: 365 L 365
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)
Query: 335 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 390
+P ++ T S ++++D H P L H Y ++ + H L+
Sbjct: 136 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 194
Query: 391 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 450
+ S D +C W D+ + P+E + TG DV+ ++ +++ +
Sbjct: 195 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 245
Query: 451 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 504
K I + + P ++ H A V + F+ + T S D TV LW ++
Sbjct: 246 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 305
Query: 505 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 563
K L+SFE + D ++ V WSP + + A RL++W+L+ E + A +G
Sbjct: 306 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 365
Query: 564 L 564
L
Sbjct: 366 L 366
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/249 (22%), Positives = 106/249 (42%), Gaps = 32/249 (12%)
Query: 1 MSDKSDLKAELERK---KQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRR 57
+ ++ L+ E RK +++L Q REE++ +ER +K + +Q+ + DRK R
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR----RQERDRKFR 1504
Query: 58 ETEALLQSIGISPEPPLVPTP-----MSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTD 112
E E Q PE + K + + Q+ G R ++ +
Sbjct: 1505 EQELRSQ----EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 113 PSVLQLQSDSELGR----RLHKLGVSKVTQVD----FLPREVVSYSKETQTPLATHQSEE 164
+ Q + + +L R R +L KV + + F+ E +E Q L + +
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 165 DEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVI 224
EDE++++ + ++ +L Q++ ++ E P+ +E +QQ+ H DR R
Sbjct: 1621 FREDEQLLQER--EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR------DRKFREE 1672
Query: 225 ERALAEDSD 233
E+ L E +
Sbjct: 1673 EQLLQEGEE 1681
Score = 44.3 bits (103), Expect = 3e-04
Identities = 49/223 (21%), Positives = 97/223 (43%), Gaps = 21/223 (9%)
Query: 10 ELERKKQRLAQIREEKKRK-------EEERKKKEADMQQKKEPVQDDSDLDRKRRETEAL 62
E ER+KQ+L + +EE++R+ EE R+++E QQ + ++ + KR+E E
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSV------- 115
LQ + E L + + E + L R + D +
Sbjct: 528 LQQ-RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 116 ---LQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMV 172
L+ + + L +RL + V ++ Q + + + E + +SEE EE +
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 173 ---ESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEE 212
E + ++ L+ +++++ +++ RE EE ++Q L EE
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Score = 39.3 bits (90), Expect = 0.011
Identities = 37/201 (18%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPE 71
ER++Q+L + +EE++ ++ R+++E +Q+ Q++ +++ R + L + + E
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 72 PPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKL 131
L + + + + L R Q + + + E RR +L
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQ-----LRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 132 GVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEV 191
+ + D+L RE E + ++E + ++ +D E E +++ ++
Sbjct: 448 KREQEERRDWLKRE----------------EETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 192 KEAPPRELTEEEKQQILHSEE 212
+E RE E +QQ+ +E
Sbjct: 492 EEEERREQQERREQQLRREQE 512
Score = 37.7 bits (86), Expect = 0.032
Identities = 38/205 (18%), Positives = 92/205 (44%), Gaps = 23/205 (11%)
Query: 11 LERKKQRLAQIREEKKRKEEERK-KKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGIS 69
L+ ++Q Q R +++R++ +RK ++E ++Q++E Q L R+ R+ + L+ +
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ----LSRQERDRKFRLEEQKVR 1589
Query: 70 PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLH 129
+ K + + Q+ R ++ D +LQ + + +L R+
Sbjct: 1590 RQ--------EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Query: 130 KLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQ 189
FL E +E + L + + E+E++++ G++ +L Q++ +
Sbjct: 1642 DR--------KFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE--GEEQQLRRQERDR 1691
Query: 190 EVKEAPPRELTEEEKQQILHSEEFL 214
+ +E + +E +++ L E+ L
Sbjct: 1692 KFREEEQQLRRQERERKFLQEEQQL 1716
Score = 36.6 bits (83), Expect = 0.072
Identities = 50/220 (22%), Positives = 99/220 (45%), Gaps = 23/220 (10%)
Query: 3 DKSDLKAELERKKQRLAQIREEKK---RKEEERKKKEADMQQKKEPVQDDSDLDRKRRET 59
++ + K E ER++QRL + +EE++ ++EEE ++ E Q++ Q D + +RRE
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHE----QERRKQQLKRDQEEERRER 487
Query: 60 EALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQ 119
L+ + + + ++ L R+ Q QL+
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ--------QLR 539
Query: 120 SDSELGR-RLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDE-----EDEEMVE 173
+ E R +L K K + + + + +E + L + E + E EE +E
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 174 SKVGQDSELENQDKKQEVKEAPPRELTEEE-KQQILHSEE 212
++ ++ E+E ++++ ++ RE EEE +QQ+L SEE
Sbjct: 600 QRLKRE-EVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Score = 35.8 bits (81), Expect = 0.12
Identities = 47/249 (18%), Positives = 99/249 (39%), Gaps = 28/249 (11%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKK--KEADMQQKKEPVQDDSDLDRKRRETE------- 60
+L++K+++L EK+R++E KK +E ++QQ++E + + R+R+E E
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Query: 61 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 120
L Q + + E ++ LG T +
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERET------------RR 1072
Query: 121 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMV--ESKVGQ 178
EL R+ K + + L E ++ + + E +E+E+++ E + +
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 179 DSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDY 238
ELE Q +++E + +L EE ++ E +R R E E+ + +
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQE-----LERQYREEEELQQEEEQLLREE 1187
Query: 239 SGRELEEKD 247
+ +E++
Sbjct: 1188 QEKRRQERE 1196
Score = 35.8 bits (81), Expect = 0.12
Identities = 44/208 (21%), Positives = 90/208 (43%), Gaps = 28/208 (13%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGIS 69
+LER++Q+ A+ R+ K ++E++ ++E + +++++ + DRK RE E LLQ
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ------ETDRKFREEEQLLQE---R 1348
Query: 70 PEPPLVPTPMSPSSKSVSTPSEAGSQDSGD--LGPLTRTLQWDTDPSVLQLQSDSELGRR 127
E PL + E Q+ G L R + + + L+ + R
Sbjct: 1349 EEQPLRRQERDRKFRE----EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 128 LHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDK 187
+L + + + +E Q + + E+E+ V + + LE + +
Sbjct: 1405 EQQLRQDRDRK----------FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 188 KQEVKEAPPRE---LTEEEKQQILHSEE 212
++ + RE L +E ++Q LH +E
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQE 1482
Score = 33.9 bits (76), Expect = 0.46
Identities = 15/53 (28%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Query: 10 ELERKKQRLAQIREEKKRKEEERK--KKEADMQQKKEPVQDDSDLDRKRRETE 60
+L++++++L + EK+R++E + +K+ +QQK+E + + R+R+E E
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Score = 33.9 bits (76), Expect = 0.46
Identities = 57/262 (21%), Positives = 102/262 (38%), Gaps = 35/262 (13%)
Query: 7 LKAELERKKQ-RLAQIREEKKRKEEERKKKEADMQQK----------KEPVQDDSDLDRK 55
L+ E E+++Q R Q REE++ + ++RK++ D Q+ KE D+ + K
Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243
Query: 56 RRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWD----T 111
RE E Q L + + G Q D R Q
Sbjct: 1244 GRENEQFRQ---------LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 112 DPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEM 171
+ L+ + E RR K K Q+ RE +ET + E +E+
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEK--QLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 172 V----ESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERA 227
+ + ++ EL +Q++ ++ E R +E +++ L E+ L +R E+
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER-----EQQ 1407
Query: 228 LAEDSDIFFDYSGRELEEKDGD 249
L +D D F ++L ++ D
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERD 1429
Score = 33.5 bits (75), Expect = 0.61
Identities = 43/204 (21%), Positives = 87/204 (42%), Gaps = 7/204 (3%)
Query: 4 KSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDR-KRRETEAL 62
+ + + E ER++QRL RE+++R+++ K++E QQ+ + Q++ R KR E E L
Sbjct: 553 EEEKRLEQERREQRLK--REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 63 LQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDS 122
Q E L + SE Q+ L R Q + + + + +
Sbjct: 611 EQE--ERREQRLKREEPEEERRQQLLKSE--EQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 123 ELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
L +RL + + + + E + ++ + Q + + E + + +
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQ 206
E Q ++QE +E R +E + Q+
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQE 750
Score = 33.5 bits (75), Expect = 0.61
Identities = 19/53 (35%), Positives = 32/53 (60%), Gaps = 5/53 (9%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQ 64
ER++Q+L + ++K +EEE+ ++E + QQ + + DRK RE E L Q
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLR-----SQESDRKFREEEQLRQ 1805
Score = 33.1 bits (74), Expect = 0.79
Identities = 18/55 (32%), Positives = 38/55 (69%), Gaps = 2/55 (3%)
Query: 8 KAELERKKQRLAQIREEKKR-KEEERK-KKEADMQQKKEPVQDDSDLDRKRRETE 60
K EL++++++L + EK+R +E ER+ ++E ++QQ++E + + R+R+E E
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Score = 33.1 bits (74), Expect = 0.79
Identities = 16/49 (32%), Positives = 30/49 (61%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRE 58
+LE ++QRL Q R+ + R EE+ +E ++++E Q++ R+ RE
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Score = 32.7 bits (73), Expect = 1.0
Identities = 35/197 (17%), Positives = 79/197 (40%), Gaps = 39/197 (19%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGIS 69
E ++++QR EEK+++ +R+++E ++Q ++++ L R+ R + + G+
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQF----LEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 70 PEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLH 129
+ SQ+ R +W + Q + E RR H
Sbjct: 858 ED-----------------QERRRSQEQ------RRDQKW-------RWQLEEERKRRRH 887
Query: 130 KLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQ 189
L Q + + +E + Q EE E+ + + ++ E Q+++Q
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEEL-----QREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 190 EVKEAPPRELTEEEKQQ 206
++E + +E ++Q
Sbjct: 943 LLREEREKRRRQERERQ 959
Score = 32.3 bits (72), Expect = 1.4
Identities = 48/227 (21%), Positives = 95/227 (41%), Gaps = 31/227 (13%)
Query: 4 KSDLKAELERKKQRLAQIREEKKRKEEERK-KKEADMQQKKEPVQDDSDLDRKRRETEAL 62
+ L E E + QR + RE+++R+E+ER+ ++E +QQ++E + + R+R+E E
Sbjct: 902 EQQLLQEEEEELQR--EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 63 L-----------QSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDL---GPLTRTLQ 108
Q +G PE K E ++ L R +
Sbjct: 960 YRKDKKLQQKEEQLLGEEPE----KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Query: 109 WDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQ---SEED 165
W+ Q + EL + +L + + + L Y +E + Q E +
Sbjct: 1016 WER-----QYRKKDELQQEEEQL-LREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
Query: 166 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEE 212
+ +E + ++ EL+ Q+++Q ++E P + +E ++Q EE
Sbjct: 1070 TRRRQELERQYRKEEELQ-QEEEQLLREEPEKRRRQERERQCREEEE 1115
Score = 32.0 bits (71), Expect = 1.8
Identities = 40/206 (19%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPE 71
+R+ + L + R+E + +EE R ++E K ++ D ++ RR L+ G +
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 72 PPLVPTPMSPSSKSVSTPSEAGSQDSGD--LGPLTRTLQWDTDPSVLQLQSDSELGRRLH 129
V E + L LQ + +LQ + E R+L
Sbjct: 227 QQ----QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 130 KLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQ---D 186
+ + + Q + ++ + ++ + + E+ EE E E + Q+ E Q +
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 187 KKQEVKEAPPRELTEEEKQQILHSEE 212
+++ ++ RE EE ++Q L E+
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQ 368
Score = 31.6 bits (70), Expect = 2.3
Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 6/69 (8%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQ-----DDSDLDRK 55
+ + L+ E E ++++L + REE+KR E+ER+++ +Q++ Q ++ R
Sbjct: 532 LRSEQQLRREQEERREQLLK-REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 56 RRETEALLQ 64
+RE E L+
Sbjct: 591 KREQEERLE 599
Score = 31.2 bits (69), Expect = 3.0
Identities = 16/58 (27%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Query: 6 DLKAELERKKQRLAQIREEKKRKEEERK---KKEADMQQKKEPVQDDSDLDRKRRETE 60
D + E R +QR EE++ + EE+K +++ Q++K+ ++++ + R+R+ET+
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETD 1335
Score = 30.8 bits (68), Expect = 3.9
Identities = 41/209 (19%), Positives = 84/209 (40%), Gaps = 50/209 (23%)
Query: 10 ELERKKQRLAQIREEKKRKEEE----RKKKEADMQQKKEPVQDDSDLDRKRRETEALLQS 65
E R+++ Q REE++ ++EE R+++E Q+++ +++ +L R++R+
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK------- 1211
Query: 66 IGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSEL- 124
+D L+W +P D+++
Sbjct: 1212 ------------------------QRYRDEDQ------RSDLKWQWEPEKENAVRDNKVY 1241
Query: 125 --GRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSEL 182
GR + + +Q+ R+ S++ L Q E D E E + +
Sbjct: 1242 CKGRENEQFRQLEDSQL----RD--RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 183 ENQDKKQEVKEAPPRELTEEEKQQILHSE 211
E Q +++E KEA R+ +E++Q+L E
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Score = 30.4 bits (67), Expect = 5.1
Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 9/65 (13%)
Query: 8 KAELERKKQRLAQIREEKKRKE---EERKKKEADMQQKKEPVQDDSDL-----DRKRRET 59
+ ELERK + Q+R+E ++++ +ER +K + +Q + P +++ L DRK RE
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR-PEREEQQLRRQERDRKFREE 1776
Query: 60 EALLQ 64
E L Q
Sbjct: 1777 EQLRQ 1781
Score = 30.4 bits (67), Expect = 5.1
Identities = 16/34 (47%), Positives = 24/34 (70%), Gaps = 2/34 (5%)
Query: 13 RKKQRLAQIREEKKRKEEERKKKEADM--QQKKE 44
R++Q L Q E+K+R+E ERK +E + QQK+E
Sbjct: 1859 REEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 30.0 bits (66), Expect = 6.7
Identities = 15/66 (22%), Positives = 41/66 (62%), Gaps = 2/66 (3%)
Query: 3 DKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQ--DDSDLDRKRRETE 60
D+ + E + ++R +R+E+++ +EE +++ ++Q+++E ++ + +L R+R+E E
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 61 ALLQSI 66
Q +
Sbjct: 295 QQQQRL 300
Score = 30.0 bits (66), Expect = 6.7
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 3 DKSDLKAELERKKQRLAQIREEKK--RKEEERK--KKEADMQQKKEPVQDDSDLDRKRRE 58
D+ + EL ++Q + EE++ R+E ERK K+E ++ ++ Q D DRK RE
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Query: 59 TEALL 63
E L
Sbjct: 1419 EEQQL 1423
Score = 30.0 bits (66), Expect = 6.7
Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 9/55 (16%)
Query: 13 RKKQRLAQIREEK---KRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQ 64
R+++R + REE+ +R+E ERK + + Q +++ +L+RK RE E L Q
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ------ELERKFREEEQLRQ 1733
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/181 (24%), Positives = 81/181 (44%), Gaps = 19/181 (10%)
Query: 413 MELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTG 472
++++Y S PV G +F + D N + SE+GTV +G ++GH PV
Sbjct: 536 LKILYGHSGPVY--GASF-SPDRNYLLSSSEDGTVRLWSLQTFTCLVG--YKGHNYPVWD 590
Query: 473 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 532
+ + FV+ D +LW T H +PL F A ++ DV + HP
Sbjct: 591 TQFS------PYGYYFVSGGHDRVARLWATDHYQPLRIF---AGHLADVNCTRFHPNSNY 641
Query: 533 CVDGMG--RLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDV 590
G + LW++ N V + ++ + ++ G+ +A G ++GR+ ++D+
Sbjct: 642 VATGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI 698
Query: 591 G 591
G
Sbjct: 699 G 699
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 45.4 bits (106), Expect = 2e-04
Identities = 60/226 (26%), Positives = 90/226 (39%), Gaps = 37/226 (16%)
Query: 6 DLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQS 65
D K E + LAQI E+E KE V D+ D+D + E L +
Sbjct: 102 DAKLTTEEVIKELAQIAGRPTEDEDE-----------KEKVADEDDVDNE--EAALLHEE 148
Query: 66 IGISPEPPLVPTPMS-----PSSKSVS-TPSEAGSQD-SGDLGPLTRTLQWD------TD 112
++ E L + P SKS T E GSQ +G+ GP T + T
Sbjct: 149 ATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTA 208
Query: 113 PSVLQLQSDSELGRRLHKLGVSKV----------TQVDFLPREVVSYSKETQTPLATHQS 162
+ S+SE G ++G + + D LPR S E +
Sbjct: 209 KAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268
Query: 163 EEDEEDEEMVESKVGQDS-ELENQDKKQEVKEAPPRELTEEEKQQI 207
EE+E+ EE E + G S E EN++ + + +EA + EEE+ +
Sbjct: 269 EEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMV 314
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,837,635
Number of Sequences: 37866
Number of extensions: 1303125
Number of successful extensions: 20176
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 412
Number of HSP's successfully gapped in prelim test: 631
Number of HSP's that attempted gapping in prelim test: 10612
Number of HSP's gapped (non-prelim): 7045
length of query: 628
length of database: 18,247,518
effective HSP length: 108
effective length of query: 520
effective length of database: 14,157,990
effective search space: 7362154800
effective search space used: 7362154800
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.