Guide to the Human Genome
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Search of human proteins with 206725447

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|206725447 leucine rich repeat containing 23 isoform a [Homo
sapiens]
         (343 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|206725447 leucine rich repeat containing 23 isoform a [Homo s...   684   0.0  
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa...   684   0.0  
gi|5901898 leucine rich repeat containing 23 isoform b [Homo sap...   508   e-144
gi|21389483 leucine-rich repeats and guanylate kinase domain con...   142   6e-34
gi|55743114 leucine rich repeat containing 49 [Homo sapiens]           93   4e-19
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap...    87   2e-17
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  80   3e-15
gi|239752518 PREDICTED: similar to leucine rich repeat containin...    77   2e-14
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s...    67   2e-11
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s...    67   2e-11
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s...    67   2e-11
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s...    67   2e-11
gi|117414162 sodium channel associated protein 2 isoform a [Homo...    66   4e-11
gi|4826651 hypothetical protein LOC755 [Homo sapiens]                  63   4e-10
gi|31621309 leucine rich repeat containing 6 [Homo sapiens]            62   7e-10
gi|66472382 nischarin [Homo sapiens]                                   60   3e-09
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo...    59   5e-09
gi|153792305 leucine rich repeat containing 58 [Homo sapiens]          59   5e-09
gi|21687175 leucine rich transmembrane and 0-methyltransferase d...    57   2e-08
gi|164607156 axonemal dynein light chain 1 [Homo sapiens]              57   2e-08
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    57   3e-08
gi|4505047 lumican precursor [Homo sapiens]                            56   5e-08
gi|16904383 leucine rich repeat containing 7 [Homo sapiens]            56   5e-08
gi|223718151 leucine rich transmembrane and 0-methyltransferase ...    55   9e-08
gi|238908508 leucine-rich repeat and death domain-containing pro...    55   1e-07
gi|118442828 beta-tubulin cofactor E [Homo sapiens]                    55   1e-07
gi|4507375 beta-tubulin cofactor E [Homo sapiens]                      55   1e-07
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    55   1e-07
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    54   2e-07
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    54   2e-07

>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score =  684 bits (1765), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60
           MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL
Sbjct: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60

Query: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120
           CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA
Sbjct: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120

Query: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180
           DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS
Sbjct: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180

Query: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240
           LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF
Sbjct: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240

Query: 241 SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE 300
           SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE
Sbjct: 241 SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE 300

Query: 301 RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI 343
           RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI
Sbjct: 301 RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI 343


>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score =  684 bits (1765), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60
           MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL
Sbjct: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60

Query: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120
           CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA
Sbjct: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120

Query: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180
           DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS
Sbjct: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180

Query: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240
           LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF
Sbjct: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240

Query: 241 SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE 300
           SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE
Sbjct: 241 SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE 300

Query: 301 RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI 343
           RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI
Sbjct: 301 RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI 343


>gi|5901898 leucine rich repeat containing 23 isoform b [Homo
           sapiens]
          Length = 312

 Score =  508 bits (1309), Expect = e-144
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60
           MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL
Sbjct: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60

Query: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120
           CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA
Sbjct: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120

Query: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180
           DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS
Sbjct: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180

Query: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240
           LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF
Sbjct: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240

Query: 241 SREMKSLQYLNLR 253
           SREMKSLQYLNLR
Sbjct: 241 SREMKSLQYLNLR 253


>gi|21389483 leucine-rich repeats and guanylate kinase domain
           containing [Homo sapiens]
          Length = 825

 Score =  142 bits (357), Expect = 6e-34
 Identities = 99/303 (32%), Positives = 163/303 (53%), Gaps = 6/303 (1%)

Query: 16  DSEKEEDEKETEEGEDYRKEGEEFP-EEWLPTPLTEDMMKEGLSLLCKTGNGLAHAYVKL 74
           DS+ +ED+ E E G +   E E    EE     L E+ + + L  L ++G+G    Y+ L
Sbjct: 73  DSDGDEDQGEGEAGSEESSESEMLNLEEEFDGVLREEAVAKALHHLGRSGSGTEQVYLNL 132

Query: 75  EVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELP 134
            +   +L D+ +L  Y+HL+ +D+S N + DLS ++ + +LL L A  N L +    + P
Sbjct: 133 TLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPP 192

Query: 135 -YLQIASFAYNQITDTEGIS-HPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLE 192
             L+ A F++NQI++   +S +  L  L L GN I  ++GL  E   +L  + L  N++ 
Sbjct: 193 KNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISGL--EMCNNLIHLSLANNKIT 250

Query: 193 STLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
           +  G+N   +K L L+ N ++ + GLEDL  L  L L  NQI +L G       L+ +NL
Sbjct: 251 TINGLNKLPIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLENH-DLLEVINL 309

Query: 253 RGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEER 312
             N +A L E+  +++LP LR L LL+NP  +++ Y    +  +  L  LD++  + EE+
Sbjct: 310 EDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWFFVIFMLLRLTELDQKKIKVEEK 369

Query: 313 AEA 315
             A
Sbjct: 370 VSA 372


>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
          Length = 686

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 81/272 (29%), Positives = 129/272 (47%), Gaps = 27/272 (9%)

Query: 73  KLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNE 132
           +L ++ + LT   ++    HLR ++   N +T +  ++ L  L+ L              
Sbjct: 94  RLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISL-------------- 139

Query: 133 LPYLQIASFAYNQITDTEGISHPR-LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQL 191
                      NQI +  G+S  R L  L L  N I  ++ L  E L SL  ++L GNQ+
Sbjct: 140 -------DLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNL--ENLKSLDVLDLHGNQI 190

Query: 192 ESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYL 250
                IN L +L+ L LA+N L  V+ L  L +LT L+LR NQI  +      +  LQ+L
Sbjct: 191 TKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN-LPCLQHL 249

Query: 251 NLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEE 310
            L  N +++   ++ L D   L  +    NP   E+ Y+   L  M  L +LD +   EE
Sbjct: 250 FLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEE 309

Query: 311 ERAEADVIRQRLKEEKEQEPEPQRDLEPEQSL 342
           ER  A V+ ++ +EEK++E   Q  L+ ++ L
Sbjct: 310 ERRMASVLAKK-EEEKKRESHKQSLLKEKKRL 340


>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
           sapiens]
          Length = 360

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 41/340 (12%)

Query: 2   SDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMK------- 54
           S+E   E+ +        +  E+  ++GE+    GEE PEE    P+  + +        
Sbjct: 24  SEESGDEEGKKHSSGIVADLSEQSLKDGEE---RGEEDPEEEHELPVDMETINLDRDAED 80

Query: 55  -----------EGLSLLCKTGN-----GLAHAYVKLE----VKERDLTD-----IYLLRS 89
                      EG  +L K         L      LE    ++E DL D     I  L +
Sbjct: 81  VDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA 140

Query: 90  YIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQ-MNELPYLQIASFAYNQITD 148
              L  +DIS N L ++  ++ LT L  L    N++   + ++ L  LQ+     N+I  
Sbjct: 141 LTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRA 200

Query: 149 TEGISH-PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLKNLY 206
            E I     LE+L L  N I  +  LD   L +L  + ++ N+L    G+ NL  L+ LY
Sbjct: 201 IENIDTLTNLESLFLGKNKITKLQNLDA--LTNLTVLSMQSNRLTKIEGLQNLVNLRELY 258

Query: 207 LAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKL 266
           L+ N ++ +EGLE+ + LT L +  N+I  +   S  +  LQ   +  N++ +  +L +L
Sbjct: 259 LSHNGIEVIEGLENNNKLTMLDIASNRIKKIENIS-HLTELQEFWMNDNLLESWSDLDEL 317

Query: 267 RDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEF 306
           +    L  + L  NP   +  YR++ ++ +P + ++D  F
Sbjct: 318 KGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATF 357


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 54/164 (32%), Positives = 95/164 (57%), Gaps = 7/164 (4%)

Query: 176 EKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQI 234
           EK + L  + L  N +     ++ L KL+ L L+ N + K+EG+E++ NL  L+L  N+I
Sbjct: 122 EKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEI 181

Query: 235 DTLSGF-SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEAL 293
           + +  +  +++KSL+ LNL+GN +++L +++KL+ L  L +L+L++NP      Y Q  +
Sbjct: 182 EHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTI 241

Query: 294 VQMPYLERLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLE 337
             +  LE L+ +    ++R EA   R  L+E +  E    RDLE
Sbjct: 242 FHLRSLESLEGQPVTTQDRQEA-FERFSLEEVERLE----RDLE 280



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 60/223 (26%), Positives = 98/223 (43%), Gaps = 27/223 (12%)

Query: 129 QMNELPYLQIASFAYNQITDTEGISHP-RLETLNLKGNSIHMVTGLDPEKLISLHTVELR 187
           ++++L  L+  + +YN+I+  EGI +   L+ LNL GN I  +     +KL SL  + L+
Sbjct: 142 KLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLK 201

Query: 188 GNQLESTLGIN----LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSRE 243
           GN++ S   I+    L  L +L L +N    V  L      T  HLR   +++L G    
Sbjct: 202 GNKISSLQDISKLKPLQDLISLILVEN---PVVTLPHYLQFTIFHLR--SLESLEGQPVT 256

Query: 244 MKSLQYLNLRGNMVANLGELAKL-RDLPK------------LRALVLLDNPCTDETSYRQ 290
            +  Q    R     +L E+ +L RDL K             R L  + N      S ++
Sbjct: 257 TQDRQEAFER----FSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKE 312

Query: 291 EALVQMPYLERLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQ 333
           EA++Q    E L  +   + E  +   I      +K+ E E +
Sbjct: 313 EAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQE 355


>gi|239752518 PREDICTED: similar to leucine rich repeat containing
           50, partial [Homo sapiens]
          Length = 489

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 3/164 (1%)

Query: 180 SLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLS 238
           +L  ++L GNQ+     IN L +L+ L LA+N L  V+ L  L +LT L+LR NQI  + 
Sbjct: 4   NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63

Query: 239 GFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPY 298
                +  LQ+L L  N +++   ++ L D   L  +    NP   E+ Y+   L  M  
Sbjct: 64  DVDN-LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQ 122

Query: 299 LERLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSL 342
           L +LD +   EEER  A V+ ++ +EEK++E   Q  L+ ++ L
Sbjct: 123 LRQLDMKRITEEERRMASVLAKK-EEEKKRESHKQSLLKEKKRL 165


>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 5/199 (2%)

Query: 145 QITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLK 203
           Q+   EGI    + +L L   +I  +  L   +  +L  ++L  N +E   G+ NL  L 
Sbjct: 33  QLAKQEGILFKDVLSLQLDFRNILRIDNL--WQFENLRKLQLDNNIIEKIEGLENLAHLV 90

Query: 204 NLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGEL 263
            L L+ N ++ +EGL+ L NL  L L +N+I  +      +K LQ L+L  N + N+  +
Sbjct: 91  WLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVK-LQVLSLGNNRIDNMMNI 149

Query: 264 AKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQ-RL 322
             LR    LR L L  NP ++   Y+      +P L  LD    ++  +  A+   Q  +
Sbjct: 150 IYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSI 209

Query: 323 KEEKEQEPEPQRDLEPEQS 341
            E K QE   Q  LE EQ+
Sbjct: 210 DELKHQENLMQAQLEDEQA 228



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/186 (23%), Positives = 76/186 (40%), Gaps = 37/186 (19%)

Query: 45  PTPLTEDMMK---------EGLSLLCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRY 95
           P  + +DM+K         E    L K    L    + L++  R++  I  L  + +LR 
Sbjct: 10  PRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRK 69

Query: 96  VDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGI-SH 154
           + +  N +  +  L  L HL+WL                       ++N I   EG+ + 
Sbjct: 70  LQLDNNIIEKIEGLENLAHLVWL---------------------DLSFNNIETIEGLDTL 108

Query: 155 PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI----NLPKLKNLYLAQN 210
             LE L+L  N I  +  LD   L+ L  + L  N++++ + I        L+ L L++N
Sbjct: 109 VNLEDLSLFNNRISKIDSLD--ALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 211 MLKKVE 216
            + + E
Sbjct: 167 PISEAE 172


>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 5/199 (2%)

Query: 145 QITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLK 203
           Q+   EGI    + +L L   +I  +  L   +  +L  ++L  N +E   G+ NL  L 
Sbjct: 33  QLAKQEGILFKDVLSLQLDFRNILRIDNL--WQFENLRKLQLDNNIIEKIEGLENLAHLV 90

Query: 204 NLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGEL 263
            L L+ N ++ +EGL+ L NL  L L +N+I  +      +K LQ L+L  N + N+  +
Sbjct: 91  WLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVK-LQVLSLGNNRIDNMMNI 149

Query: 264 AKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQ-RL 322
             LR    LR L L  NP ++   Y+      +P L  LD    ++  +  A+   Q  +
Sbjct: 150 IYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSI 209

Query: 323 KEEKEQEPEPQRDLEPEQS 341
            E K QE   Q  LE EQ+
Sbjct: 210 DELKHQENLMQAQLEDEQA 228



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/186 (23%), Positives = 76/186 (40%), Gaps = 37/186 (19%)

Query: 45  PTPLTEDMMK---------EGLSLLCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRY 95
           P  + +DM+K         E    L K    L    + L++  R++  I  L  + +LR 
Sbjct: 10  PRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRK 69

Query: 96  VDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGI-SH 154
           + +  N +  +  L  L HL+WL                       ++N I   EG+ + 
Sbjct: 70  LQLDNNIIEKIEGLENLAHLVWL---------------------DLSFNNIETIEGLDTL 108

Query: 155 PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI----NLPKLKNLYLAQN 210
             LE L+L  N I  +  LD   L+ L  + L  N++++ + I        L+ L L++N
Sbjct: 109 VNLEDLSLFNNRISKIDSLD--ALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 211 MLKKVE 216
            + + E
Sbjct: 167 PISEAE 172


>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 5/199 (2%)

Query: 145 QITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLK 203
           Q+   EGI    + +L L   +I  +  L   +  +L  ++L  N +E   G+ NL  L 
Sbjct: 33  QLAKQEGILFKDVLSLQLDFRNILRIDNL--WQFENLRKLQLDNNIIEKIEGLENLAHLV 90

Query: 204 NLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGEL 263
            L L+ N ++ +EGL+ L NL  L L +N+I  +      +K LQ L+L  N + N+  +
Sbjct: 91  WLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVK-LQVLSLGNNRIDNMMNI 149

Query: 264 AKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQ-RL 322
             LR    LR L L  NP ++   Y+      +P L  LD    ++  +  A+   Q  +
Sbjct: 150 IYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSI 209

Query: 323 KEEKEQEPEPQRDLEPEQS 341
            E K QE   Q  LE EQ+
Sbjct: 210 DELKHQENLMQAQLEDEQA 228



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/186 (23%), Positives = 76/186 (40%), Gaps = 37/186 (19%)

Query: 45  PTPLTEDMMK---------EGLSLLCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRY 95
           P  + +DM+K         E    L K    L    + L++  R++  I  L  + +LR 
Sbjct: 10  PRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRK 69

Query: 96  VDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGI-SH 154
           + +  N +  +  L  L HL+WL                       ++N I   EG+ + 
Sbjct: 70  LQLDNNIIEKIEGLENLAHLVWL---------------------DLSFNNIETIEGLDTL 108

Query: 155 PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI----NLPKLKNLYLAQN 210
             LE L+L  N I  +  LD   L+ L  + L  N++++ + I        L+ L L++N
Sbjct: 109 VNLEDLSLFNNRISKIDSLD--ALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 211 MLKKVE 216
            + + E
Sbjct: 167 PISEAE 172


>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 5/199 (2%)

Query: 145 QITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLK 203
           Q+   EGI    + +L L   +I  +  L   +  +L  ++L  N +E   G+ NL  L 
Sbjct: 33  QLAKQEGILFKDVLSLQLDFRNILRIDNL--WQFENLRKLQLDNNIIEKIEGLENLAHLV 90

Query: 204 NLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGEL 263
            L L+ N ++ +EGL+ L NL  L L +N+I  +      +K LQ L+L  N + N+  +
Sbjct: 91  WLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVK-LQVLSLGNNRIDNMMNI 149

Query: 264 AKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQ-RL 322
             LR    LR L L  NP ++   Y+      +P L  LD    ++  +  A+   Q  +
Sbjct: 150 IYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSI 209

Query: 323 KEEKEQEPEPQRDLEPEQS 341
            E K QE   Q  LE EQ+
Sbjct: 210 DELKHQENLMQAQLEDEQA 228



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/186 (23%), Positives = 76/186 (40%), Gaps = 37/186 (19%)

Query: 45  PTPLTEDMMK---------EGLSLLCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRY 95
           P  + +DM+K         E    L K    L    + L++  R++  I  L  + +LR 
Sbjct: 10  PRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRK 69

Query: 96  VDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGI-SH 154
           + +  N +  +  L  L HL+WL                       ++N I   EG+ + 
Sbjct: 70  LQLDNNIIEKIEGLENLAHLVWL---------------------DLSFNNIETIEGLDTL 108

Query: 155 PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI----NLPKLKNLYLAQN 210
             LE L+L  N I  +  LD   L+ L  + L  N++++ + I        L+ L L++N
Sbjct: 109 VNLEDLSLFNNRISKIDSLD--ALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 211 MLKKVE 216
            + + E
Sbjct: 167 PISEAE 172


>gi|117414162 sodium channel associated protein 2 isoform a [Homo
           sapiens]
          Length = 1032

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 54/156 (34%), Positives = 80/156 (51%), Gaps = 11/156 (7%)

Query: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKV 215
           L  +NL  N+I  +  +D   + +L  ++L  NQ+    G+N L KL  L L+ N++ KV
Sbjct: 45  LHAVNLHCNNISKIEAID--HIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKV 102

Query: 216 EGLEDLSNLTTLHLRDNQIDTLSG---FSREMKSLQYLNLRGNMVANLGELAK-LRDLPK 271
           EGLE+L NLT L++  N ID LSG          L+Y++L  N + ++  L + +  L  
Sbjct: 103 EGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCMVGLHF 162

Query: 272 LRALVLL----DNPCTDETSYRQEALVQMPYLERLD 303
           L  L+L     DNP      YR   L  +P L  LD
Sbjct: 163 LTNLILEKDGDDNPVCRLPGYRAVILQTLPQLRILD 198



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 5/79 (6%)

Query: 81  LTDIYLLRSYIHLRYVDISENHLTDLS---PLNYLTH-LLWLKADGNRLRSAQMNELPYL 136
           +T +  L   I+L  +++S NH+ DLS   PL+ + H L ++    NR+ S   + L  +
Sbjct: 99  ITKVEGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIH-HLLQCM 157

Query: 137 QIASFAYNQITDTEGISHP 155
               F  N I + +G  +P
Sbjct: 158 VGLHFLTNLILEKDGDDNP 176


>gi|4826651 hypothetical protein LOC755 [Homo sapiens]
          Length = 256

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 9/139 (6%)

Query: 199 LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVA 258
           L  ++ L    + L  +   +++ +L  + L  N I TL   SR  + L  L LR N + 
Sbjct: 17  LHSVRKLNCWGSRLTDISICQEMPSLEVITLSVNSISTLEPVSR-CQRLSELYLRRNRIP 75

Query: 259 NLGELAKLRDLPKLRALVLLDNPC--TDETSYRQEALVQMPYLERLDKEFYEEEERAEAD 316
           +L EL  L+ LP+LR L L +NPC  T    YR   L  +P L++LD +   EEE + A 
Sbjct: 76  SLAELFYLKGLPRLRVLWLAENPCCGTSPHRYRMTVLRTLPRLQKLDNQAVTEEELSRA- 134

Query: 317 VIRQRLKEEKEQEPEPQRD 335
                L E +E    P+R+
Sbjct: 135 -----LSEGEEITAAPERE 148


>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
          Length = 466

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 46/168 (27%), Positives = 79/168 (47%), Gaps = 7/168 (4%)

Query: 178 LISLHTVELRGNQLESTLGIN--LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQID 235
           + SL  + L   ++E    I+     LK LYL  N++ K+E +  L  L  L+L  N I+
Sbjct: 20  IFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIE 79

Query: 236 TLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQ 295
            +       + L  L+L  N +  L  +  L+    L+ L L+ NPC     YR+  +  
Sbjct: 80  KIENLEG-CEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVAT 138

Query: 296 MPYLERLDKEFYEEEERAEA----DVIRQRLKEEKEQEPEPQRDLEPE 339
           +P L+ LD +  E  ER +A     VI  +++E+++     +  L+ E
Sbjct: 139 LPQLKWLDGKEIEPSERIKALQDYSVIEPQIREQEKDHCLKRAKLKEE 186


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 55/189 (29%), Positives = 90/189 (47%), Gaps = 36/189 (19%)

Query: 155 PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN--LPKLKNLYLAQNML 212
           P++E L+L  N + +V  L  + L +L  ++L  N+L S  G++  L  +K L LA N+L
Sbjct: 310 PKIEFLDLSHNGLLVVDNL--QHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLL 367

Query: 213 KKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKL 272
           + + GL  L +L  L LRDN+I+ +                        E+  +  LP L
Sbjct: 368 ESLSGLHKLYSLVNLDLRDNRIEQME-----------------------EVRSIGSLPCL 404

Query: 273 RALVLLDNPCTDETSYRQEALVQMPYLER-----LDKEFYEEEERAEADVIR--QRLKEE 325
             + LL+NP +    YR + L Q  + ER     LD     E+E    +V++  Q+ KE 
Sbjct: 405 EHVSLLNNPLSIIPDYRTKVLAQ--FGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEV 462

Query: 326 KEQEPEPQR 334
           K +   P++
Sbjct: 463 KSKLSNPEK 471



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/127 (28%), Positives = 63/127 (49%), Gaps = 31/127 (24%)

Query: 93  LRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGI 152
           + ++D+S N L  +  L +L +L+ L                       +YN+++  EG+
Sbjct: 312 IEFLDLSHNGLLVVDNLQHLYNLVHL---------------------DLSYNKLSSLEGL 350

Query: 153 SHPRL---ETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI----NLPKLKNL 205
            H +L   +TLNL GN +  ++GL   KL SL  ++LR N++E    +    +LP L+++
Sbjct: 351 -HTKLGNIKTLNLAGNLLESLSGL--HKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHV 407

Query: 206 YLAQNML 212
            L  N L
Sbjct: 408 SLLNNPL 414


>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
           sapiens]
          Length = 255

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 40/136 (29%), Positives = 70/136 (51%), Gaps = 3/136 (2%)

Query: 184 VELRGNQLE--STLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLS-GF 240
           ++LRG ++     LG  L +   +  + N ++K++G   L  L TL + +N+I  +  G 
Sbjct: 24  LDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGL 83

Query: 241 SREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE 300
            + +  L  L L  N +  LG+L  L  L  L  L +L NP T++  YR   + ++P + 
Sbjct: 84  DQALPCLTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVR 143

Query: 301 RLDKEFYEEEERAEAD 316
            LD +  + +ER EA+
Sbjct: 144 VLDFQKVKLKERQEAE 159


>gi|153792305 leucine rich repeat containing 58 [Homo sapiens]
          Length = 371

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 71/245 (28%), Positives = 110/245 (44%), Gaps = 22/245 (8%)

Query: 43  WLPTPLTEDMMKEGLSLLCKTGNGLAHAYVKLEVKERDLTDI--YLLRSYIHLRYVDISE 100
           W    ++ + ++  L    +   G   A ++L +    L  +   L   + HL+ +D+S 
Sbjct: 18  WSRLSVSTETLESELEARGEERRGAREALLRLLLPHNRLVSLPRALGSGFPHLQLLDVSG 77

Query: 101 NHLTDLSP-LNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLET 159
           N LT L P L  L  L  L A  NRL        P       A + +  +       L+ 
Sbjct: 78  NALTALGPELLALRGLRTLLAKNNRLGG------PSALPKGLAQSPLCRS-------LQV 124

Query: 160 LNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLG--INLPKLKNLYLAQNMLKKV-E 216
           LNL GN    V     E L +L T+ L GNQL+S      NL  L+ LYL  N +K++  
Sbjct: 125 LNLSGNCFQEVPASLLE-LRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPP 183

Query: 217 GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALV 276
            L +L +L  L L DN+I ++     ++ SL+ L+L  N++  L    ++ +L  L  L 
Sbjct: 184 ELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPR--EILNLIHLEELS 241

Query: 277 LLDNP 281
           L  NP
Sbjct: 242 LRGNP 246


>gi|21687175 leucine rich transmembrane and 0-methyltransferase
           domain containing isoform 1 [Homo sapiens]
          Length = 192

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 48/171 (28%), Positives = 76/171 (44%), Gaps = 6/171 (3%)

Query: 160 LNLKGNSIHMVTGL---DPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE 216
           L+    SIH++  L   +P   +        G  L  +L +N   L +L     +  ++ 
Sbjct: 16  LDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQL- 74

Query: 217 GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALV 276
            LE   NL  + L  N + ++        +L  L L GN +  LGE+ KL  LP+LR+L 
Sbjct: 75  -LEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLT 133

Query: 277 LLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADV-IRQRLKEEK 326
           L  NP  +E  YRQ  L  +  +   D     + +R  A+V  R  +K +K
Sbjct: 134 LHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKK 184


>gi|164607156 axonemal dynein light chain 1 [Homo sapiens]
          Length = 190

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 7/132 (5%)

Query: 178 LISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSN-LTTLHLRDNQID 235
           L +   + L  N +E    +N L  L+ L L +N +K + GLE + + L  L +  N I+
Sbjct: 47  LANCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIE 106

Query: 236 TLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTD----ETSYRQE 291
            L G    MK L+ L +  N+V +  E  KL +LP L  LV + NP  +    E ++ +E
Sbjct: 107 KLKGI-HIMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGNPLEEKHSAENNWIEE 165

Query: 292 ALVQMPYLERLD 303
           A  ++P L++LD
Sbjct: 166 ATKRVPKLKKLD 177


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 46/146 (31%), Positives = 72/146 (49%), Gaps = 6/146 (4%)

Query: 201 KLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDT-LSGFSREMKSLQYLNLRGNMVAN 259
           +L+ L +A   L  +  L  L+ L  L L DN I   L   + +  +L YLNL GN + +
Sbjct: 43  ELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKD 102

Query: 260 LGELAKLRDLPKLRALVLLDNPCTDETSYRQ---EALVQMPYLERLDKEFYEEEERAEAD 316
           L  +  L++L  L++L L +   T+   YR+   E L Q+ YL+  D+E  E  +  E D
Sbjct: 103 LSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEED 162

Query: 317 VI--RQRLKEEKEQEPEPQRDLEPEQ 340
                +  +EE+E E  P    E E+
Sbjct: 163 DEDGDEDDEEEEENEAGPPEGYEEEE 188



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 7/67 (10%)

Query: 3   DEDDLEDSEPDQDDSEKEEDE-------KETEEGEDYRKEGEEFPEEWLPTPLTEDMMKE 55
           D ++ +D + D+DD E+EE+E       +E EE E+   E E+  E+   + L E   + 
Sbjct: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216

Query: 56  GLSLLCK 62
           GLS L K
Sbjct: 217 GLSYLMK 223



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 16/40 (40%), Positives = 26/40 (65%), Gaps = 1/40 (2%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEE 42
           ++++  DSE ++DD + +ED++E EE E    EG E  EE
Sbjct: 151 EDNEAPDSE-EEDDEDGDEDDEEEEENEAGPPEGYEEEEE 189



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 4/43 (9%)

Query: 4   EDDLEDSEPDQDDSEKEEDEKETEE----GEDYRKEGEEFPEE 42
           +++++D E D D  E+ E+E+E EE    GE  +++ E+  EE
Sbjct: 223 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 15/55 (27%)

Query: 3   DEDDLEDSEPDQDDSEKE---------------EDEKETEEGEDYRKEGEEFPEE 42
           +E++ ED + D+D++  E               E+ ++ E+ +DY +EGEE  EE
Sbjct: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245


>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 12/123 (9%)

Query: 142 AYNQITDTEGI--SHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINL 199
           A+  +TD + +   H  LE   +KG            KL  L  + +  N L  ++G   
Sbjct: 85  AFENVTDLQWLILDHNLLENSKIKGRVF--------SKLKQLKKLHINHNNLTESVGPLP 136

Query: 200 PKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQI--DTLSGFSREMKSLQYLNLRGNMV 257
             L++L L  N + K+   E L NLT +HL+ N++  D +S   + +KSL+YL+L  N +
Sbjct: 137 KSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQI 196

Query: 258 ANL 260
           A L
Sbjct: 197 ARL 199


>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
          Length = 1537

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 68/256 (26%), Positives = 116/256 (45%), Gaps = 26/256 (10%)

Query: 92  HLRYVDISENHLTDL-SPLNYLTHLLWLKADGNRLRSAQMN-----ELPYLQIASFAYNQ 145
           +LR + +  N L  L   +  L  L++L    NR+ +  M+      L  L ++S    Q
Sbjct: 208 NLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQ 267

Query: 146 ITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLES---TLGINLPKL 202
           + D+ G+   +L TL +  N + M+       L  L   +   N+LES   T+G  L  L
Sbjct: 268 LPDSIGLLK-KLTTLKVDDNQLTMLPNTIGN-LSLLEEFDCSCNELESLPSTIGY-LHSL 324

Query: 203 KNLYLAQNMLKKV-EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLG 261
           + L + +N L ++   +    N+T + LR N+++ L     +M+ L+ LNL  N + NL 
Sbjct: 325 RTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLP 384

Query: 262 -ELAKLRDLPKL-------RALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERA 313
               KL++L  L       +AL+ L      ET  R       P   R D++F     ++
Sbjct: 385 FSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDF-----QS 439

Query: 314 EADVIRQRLKEEKEQE 329
           ++D     L EE+ Q+
Sbjct: 440 DSDSFNPTLWEEQRQQ 455


>gi|223718151 leucine rich transmembrane and 0-methyltransferase
           domain containing isoform 2 [Homo sapiens]
          Length = 158

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 5/142 (3%)

Query: 160 LNLKGNSIHMVTGL---DPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE 216
           L+    SIH++  L   +P   +        G  L  +L +N   L +L     +  ++ 
Sbjct: 16  LDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQL- 74

Query: 217 GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALV 276
            LE   NL  + L  N + ++        +L  L L GN +  LGE+ KL  LP+LR+L 
Sbjct: 75  -LEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLT 133

Query: 277 LLDNPCTDETSYRQEALVQMPY 298
           L  NP  +E  YR    V+MP+
Sbjct: 134 LHGNPMEEEKGYRVPGSVEMPH 155


>gi|238908508 leucine-rich repeat and death domain-containing
           protein [Homo sapiens]
          Length = 860

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 53/203 (26%), Positives = 100/203 (49%), Gaps = 12/203 (5%)

Query: 89  SYIHLRYVDISENHLTDL--SPLNYLT-HLLWLKADGNRLRSAQMNELPYLQIASFAYNQ 145
           S I+L+Y+D+ +N +  +  S  N ++ H+L L  +       ++  L  LQ+   + NQ
Sbjct: 531 SLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQ 590

Query: 146 IT--DTEGISHPRLETLNLKGNS-IHMVTGL-DPEKLISLHTVELRGNQLESTLG--INL 199
           +    ++  +   ++ LN   N  IH    L   + L  L+  +++G +L    G   N+
Sbjct: 591 LQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNM 650

Query: 200 PKLKNLYLAQNMLKKV-EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVA 258
            +LK L ++ N ++++   + +L NL +LH  +NQI  L      +  LQ LNL GN + 
Sbjct: 651 TQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLT 710

Query: 259 NLGELAKLRDLPKLRALVLLDNP 281
            L   + + ++  L+ +   DNP
Sbjct: 711 ALP--SAIYNIFSLKEINFDDNP 731



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 47/186 (25%), Positives = 84/186 (45%), Gaps = 12/186 (6%)

Query: 105 DLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEG---ISHPRLETLN 161
           D+  + Y+ +L   K      + A   +L  L+I S   N ++       + H  L  LN
Sbjct: 159 DILKIKYVKYLYLDKNQIKTFQGADSGDLLGLEILSLQENGLSSLPSEIQLLH-NLRILN 217

Query: 162 LKGNSIHMVTGLDPEKLISLHTVELRGNQLE---STLGINLPKLKNLYLAQNMLKKV-EG 217
           +  N I  +   +  +L ++  +    N +E   S L   L  L+ L L +N L+ + + 
Sbjct: 218 VSHNHISHIPK-EISQLGNIRQLFFYNNYIENFPSDLEC-LGNLEILSLGKNKLRHIPDT 275

Query: 218 LEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVL 277
           L  L  L  L+L  NQ+ T       +  L  L+L GN++++L +  ++R+L  L  L++
Sbjct: 276 LPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPK--EIRELKNLETLLM 333

Query: 278 LDNPCT 283
             N  T
Sbjct: 334 DHNKLT 339



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 43/181 (23%), Positives = 85/181 (46%), Gaps = 19/181 (10%)

Query: 93  LRYVDISENHLTDL-SPLNYLTHLLWLKADGNRLRSA--QMNELPYLQIASFAYNQIT-- 147
           LR +++  N LT     L +L  L+ L   GN + S   ++ EL  L+     +N++T  
Sbjct: 282 LRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFL 341

Query: 148 DTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLPK------ 201
             E     +++ L L  N + +++     K+ +    ELR   L+  L  N+P+      
Sbjct: 342 AVEIFQLLKIKELQLADNKLEVIS----HKIENFR--ELRILILDKNLLKNIPEKISCCA 395

Query: 202 -LKNLYLAQNMLKKV-EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVAN 259
            L+ L L+ N L ++ + +  L+NL  LH+  N +  ++     + ++  L   GN++ +
Sbjct: 396 MLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKITDCISHLNNICSLEFSGNIITD 455

Query: 260 L 260
           +
Sbjct: 456 V 456


>gi|118442828 beta-tubulin cofactor E [Homo sapiens]
          Length = 527

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 72/269 (26%), Positives = 117/269 (43%), Gaps = 42/269 (15%)

Query: 92  HLRYVDISENHLTDLSPL----NYLTHLLWLKADGNRLR----SAQMNELPYLQIASFAY 143
           ++R VD+S+N L+    +    + L HL  L    N+L+    S     L  L++     
Sbjct: 154 NIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQ 213

Query: 144 NQITDTEGI----SHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQL----ESTL 195
             IT  E +      P LE L L+ N+I  ++    + L ++  ++L  NQL    +  L
Sbjct: 214 TGITWAEVLRCVAGCPGLEELYLESNNI-FISERPTDVLQTVKLLDLSSNQLIDENQLYL 272

Query: 196 GINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGN 255
             +LP+L+ L L+             + +++LH  D  I   +       SL+YL +  N
Sbjct: 273 IAHLPRLEQLILSD------------TGISSLHFPDAGIGCKTSM---FPSLKYLVVNDN 317

Query: 256 MVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEA----LVQMPYLERLDK--EFYEE 309
            ++      +L  LP LRAL  L NP T E    + A    +  +  L+ L+K     EE
Sbjct: 318 QISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEE 377

Query: 310 EERAEADVIRQRLKEEKE----QEPEPQR 334
             RAE D  +    E K+    ++PE  R
Sbjct: 378 RRRAELDYRKAFGNEWKQAGGHKDPEKNR 406


>gi|4507375 beta-tubulin cofactor E [Homo sapiens]
          Length = 527

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 72/269 (26%), Positives = 117/269 (43%), Gaps = 42/269 (15%)

Query: 92  HLRYVDISENHLTDLSPL----NYLTHLLWLKADGNRLR----SAQMNELPYLQIASFAY 143
           ++R VD+S+N L+    +    + L HL  L    N+L+    S     L  L++     
Sbjct: 154 NIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQ 213

Query: 144 NQITDTEGI----SHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQL----ESTL 195
             IT  E +      P LE L L+ N+I  ++    + L ++  ++L  NQL    +  L
Sbjct: 214 TGITWAEVLRCVAGCPGLEELYLESNNI-FISERPTDVLQTVKLLDLSSNQLIDENQLYL 272

Query: 196 GINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGN 255
             +LP+L+ L L+             + +++LH  D  I   +       SL+YL +  N
Sbjct: 273 IAHLPRLEQLILSD------------TGISSLHFPDAGIGCKTSM---FPSLKYLVVNDN 317

Query: 256 MVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEA----LVQMPYLERLDK--EFYEE 309
            ++      +L  LP LRAL  L NP T E    + A    +  +  L+ L+K     EE
Sbjct: 318 QISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEE 377

Query: 310 EERAEADVIRQRLKEEKE----QEPEPQR 334
             RAE D  +    E K+    ++PE  R
Sbjct: 378 RRRAELDYRKAFGNEWKQAGGHKDPEKNR 406


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 44/140 (31%), Positives = 68/140 (48%), Gaps = 6/140 (4%)

Query: 207 LAQNMLKKVEGLEDLSNLTTLHLRDNQIDT-LSGFSREMKSLQYLNLRGNMVANLGELAK 265
           +A   L  +  L  L+ L  L L DN I   L   + +  +L YLNL GN + +L  +  
Sbjct: 1   MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA 60

Query: 266 LRDLPKLRALVLLDNPCTDETSYRQ---EALVQMPYLERLDKEFYEEEERAEADVI--RQ 320
           L++L  L++L L +   T+   YR+   E L Q+ YL+  D+E  E  +  E D     +
Sbjct: 61  LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE 120

Query: 321 RLKEEKEQEPEPQRDLEPEQ 340
             +EE+E E  P    E E+
Sbjct: 121 DDEEEEENEAGPPEGYEEEE 140



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 7/67 (10%)

Query: 3   DEDDLEDSEPDQDDSEKEEDE-------KETEEGEDYRKEGEEFPEEWLPTPLTEDMMKE 55
           D ++ +D + D+DD E+EE+E       +E EE E+   E E+  E+   + L E   + 
Sbjct: 109 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 168

Query: 56  GLSLLCK 62
           GLS L K
Sbjct: 169 GLSYLMK 175



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 16/40 (40%), Positives = 26/40 (65%), Gaps = 1/40 (2%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEE 42
           ++++  DSE ++DD + +ED++E EE E    EG E  EE
Sbjct: 103 EDNEAPDSE-EEDDEDGDEDDEEEEENEAGPPEGYEEEEE 141



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 4/43 (9%)

Query: 4   EDDLEDSEPDQDDSEKEEDEKETEE----GEDYRKEGEEFPEE 42
           +++++D E D D  E+ E+E+E EE    GE  +++ E+  EE
Sbjct: 175 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 217



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 15/55 (27%)

Query: 3   DEDDLEDSEPDQDDSEKE---------------EDEKETEEGEDYRKEGEEFPEE 42
           +E++ ED + D+D++  E               E+ ++ E+ +DY +EGEE  EE
Sbjct: 143 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 197


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 36/127 (28%), Positives = 63/127 (49%), Gaps = 3/127 (2%)

Query: 212 LKKVEGLEDLSNLTTLHLRDNQIDT-LSGFSREMKSLQYLNLRGNMVANLGELAKLRDLP 270
           L  +  L  L+ L  L L DN++   L   + +  +L +LNL GN + +L  +  L+ L 
Sbjct: 54  LTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLE 113

Query: 271 KLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADV--IRQRLKEEKEQ 328
            L++L L +   T+   YR+     +P L  LD    +++E  ++D     + L +E+E 
Sbjct: 114 NLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEED 173

Query: 329 EPEPQRD 335
           E E + D
Sbjct: 174 EDEEEYD 180



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 3/45 (6%)

Query: 1   MSDEDDLEDSEPDQDDS---EKEEDEKETEEGEDYRKEGEEFPEE 42
           + DE++ ED E   +D+   E EEDE E EEGE+    GEE  +E
Sbjct: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDE 211



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 2/36 (5%)

Query: 5   DDLEDSEPDQDDSEKEEDEK--ETEEGEDYRKEGEE 38
           + L+D E D+D+ E +ED +  E EE ED  +EGEE
Sbjct: 165 EGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEE 200



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKETEEGE-DYRKEGEEFPEE 42
           DED+ E+ E +    E+EEDE+   +GE D  ++ EE  EE
Sbjct: 191 DEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEE 231



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 4/43 (9%)

Query: 3   DEDDLEDSEPDQD----DSEKEEDEKETEEGEDYRKEGEEFPE 41
           +E+D ++ E D+D    + E++EDE+E  E ED   E EE  E
Sbjct: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEE 212


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 2/140 (1%)

Query: 202 LKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQI-DTLSGFSREMKSLQYLNLRGNMVANL 260
           L+ L L    L  V  L  L  L  L L +N+I   L   + ++ +L +LNL GN + ++
Sbjct: 44  LEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDI 103

Query: 261 GELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQ 320
             L  L+ L  L++L L +   T+   YR+     +P L  LD    E++E  ++D    
Sbjct: 104 STLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVD 163

Query: 321 RLKEEKE-QEPEPQRDLEPE 339
            + EE+E +E E + D + E
Sbjct: 164 GVDEEEEDEEGEDEEDEDDE 183



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 16/40 (40%), Positives = 26/40 (65%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEE 42
           +ED+  + E D+DD + EE+E + E+ ED   EG+E  +E
Sbjct: 169 EEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDE 208



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 14/41 (34%), Positives = 27/41 (65%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEW 43
           DE+D +D + ++++ ++E+DE E  EG++   E  E  EE+
Sbjct: 176 DEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEF 216



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 5/45 (11%)

Query: 3   DEDDLE----DSEPDQDDSEKEEDEKETEEGEDYRK-EGEEFPEE 42
           D +D E    D+E D  D E+E++E E EE ED    E EEF EE
Sbjct: 149 DREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEE 193



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 16/40 (40%), Positives = 23/40 (57%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEE 42
           DE+D ED + + D+ + E  E+E E G D   E E+  EE
Sbjct: 191 DEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEE 230



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 3/39 (7%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKE---TEEGEDYRKEGEE 38
           ++D+ ED E D+DD E  E+E+E    EE ED  ++ EE
Sbjct: 193 EDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEE 231



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 2/42 (4%)

Query: 3   DEDDLEDSEPDQDDSEKE--EDEKETEEGEDYRKEGEEFPEE 42
           D  D ED E    D+E +  ++E+E EEGED   E +E  EE
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEE 187



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 8/48 (16%)

Query: 3   DEDDLEDSEPDQD--------DSEKEEDEKETEEGEDYRKEGEEFPEE 42
           DEDD E SE +++        D +++E+E+E  +GE  ++E ++  E+
Sbjct: 203 DEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGED 250



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 14/46 (30%), Positives = 28/46 (60%), Gaps = 6/46 (13%)

Query: 3   DEDDLEDSEPDQDDSEKEE------DEKETEEGEDYRKEGEEFPEE 42
           D++D E+ E D++D E E+      D++ +EE E++  + E+  E+
Sbjct: 181 DDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDED 226


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,542,540
Number of Sequences: 37866
Number of extensions: 651525
Number of successful extensions: 13149
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 308
Number of HSP's that attempted gapping in prelim test: 6765
Number of HSP's gapped (non-prelim): 4488
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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