Guide to the Human Genome
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Search of human proteins with 205360962

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
         (4302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]         8665   0.0  
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]         8660   0.0  
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]             326   3e-88
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo...   179   4e-44
gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]            179   5e-44
gi|31559825 polycystin 1-like 3 [Homo sapiens]                        178   9e-44
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo...   178   1e-43
gi|239745435 PREDICTED: hypothetical protein XP_002343464 [Homo ...   168   9e-41
gi|4505835 polycystin 2 [Homo sapiens]                                122   1e-26
gi|19923084 polycystin-1L1 [Homo sapiens]                             121   2e-26
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]         110   2e-23
gi|5174633 receptor for egg jelly-like protein precursor [Homo s...   103   5e-21
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]         84   2e-15
gi|194306623 immunoglobulin superfamily containing leucine-rich ...    81   2e-14
gi|194306621 immunoglobulin superfamily containing leucine-rich ...    81   2e-14
gi|39930401 immunoglobulin superfamily containing leucine-rich r...    81   2e-14
gi|194306618 immunoglobulin superfamily containing leucine-rich ...    81   2e-14
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    78   2e-13
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap...    75   1e-12
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap...    75   1e-12
gi|59823631 G protein-coupled receptor 125 [Homo sapiens]              75   2e-12
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]    74   4e-12
gi|188528675 slit homolog 1 [Homo sapiens]                             73   5e-12
gi|4758460 glycoprotein V (platelet) [Homo sapiens]                    72   2e-11
gi|41582239 immunoglobulin superfamily containing leucine-rich r...    71   3e-11
gi|5031809 immunoglobulin superfamily containing leucine-rich re...    71   3e-11
gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens]         69   8e-11
gi|11321571 slit homolog 3 [Homo sapiens]                              69   1e-10
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho...    69   1e-10
gi|4759146 slit homolog 2 [Homo sapiens]                               68   2e-10

>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score = 8665 bits (22484), Expect = 0.0
 Identities = 4302/4302 (100%), Positives = 4302/4302 (100%)

Query: 1    MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60
            MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
Sbjct: 1    MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60

Query: 61   PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120
            PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
Sbjct: 61   PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120

Query: 121  NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180
            NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
Sbjct: 121  NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180

Query: 181  VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240
            VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
Sbjct: 181  VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240

Query: 241  SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300
            SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV
Sbjct: 241  SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300

Query: 301  TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360
            TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE
Sbjct: 301  TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360

Query: 361  LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420
            LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY
Sbjct: 361  LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420

Query: 421  RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480
            RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP
Sbjct: 421  RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480

Query: 481  APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540
            APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD
Sbjct: 481  APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540

Query: 541  AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600
            AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR
Sbjct: 541  AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600

Query: 601  RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660
            RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC
Sbjct: 601  RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660

Query: 661  HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720
            HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD
Sbjct: 661  HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720

Query: 721  AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780
            AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
Sbjct: 721  AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780

Query: 781  LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840
            LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT
Sbjct: 781  LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840

Query: 841  NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900
            NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP
Sbjct: 841  NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900

Query: 901  WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960
            WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG
Sbjct: 901  WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960

Query: 961  SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020
            SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ
Sbjct: 961  SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020

Query: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080
            GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP
Sbjct: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080

Query: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140
            SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA
Sbjct: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140

Query: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200
            GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA
Sbjct: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200

Query: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260
            AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV
Sbjct: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260

Query: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320
            EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN
Sbjct: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320

Query: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380
            PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV
Sbjct: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380

Query: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440
            GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS
Sbjct: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440

Query: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500
            YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW
Sbjct: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500

Query: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560
            DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV
Sbjct: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560

Query: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620
            PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA
Sbjct: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620

Query: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680
            QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG
Sbjct: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680

Query: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740
            KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA
Sbjct: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740

Query: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800
            ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV
Sbjct: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800

Query: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860
            PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG
Sbjct: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860

Query: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920
            TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR
Sbjct: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920

Query: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980
            LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC
Sbjct: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980

Query: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040
            EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV
Sbjct: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040

Query: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100
            RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS
Sbjct: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100

Query: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160
            PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL
Sbjct: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160

Query: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220
            MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR
Sbjct: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220

Query: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280
            LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE
Sbjct: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280

Query: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340
            SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL
Sbjct: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340

Query: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400
            TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS
Sbjct: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400

Query: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460
            KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC
Sbjct: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460

Query: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520
            ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
Sbjct: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520

Query: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580
            HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS
Sbjct: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580

Query: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640
            ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA
Sbjct: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640

Query: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700
            QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA
Sbjct: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700

Query: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760
            ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM
Sbjct: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760

Query: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820
            RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS
Sbjct: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820

Query: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880
            DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS
Sbjct: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880

Query: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940
            DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP
Sbjct: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940

Query: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000
            YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR
Sbjct: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000

Query: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060
            WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
Sbjct: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060

Query: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120
            HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY
Sbjct: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120

Query: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180
            EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW
Sbjct: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180

Query: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240
            KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA
Sbjct: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240

Query: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300
            ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG
Sbjct: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300

Query: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360
            AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA
Sbjct: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360

Query: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWP 3420
            GQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWP
Sbjct: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWP 3420

Query: 3421 DLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGV 3480
            DLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGV
Sbjct: 3421 DLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGV 3480

Query: 3481 SSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGL 3540
            SSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGL
Sbjct: 3481 SSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGL 3540

Query: 3541 VEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFL 3600
            VEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFL
Sbjct: 3541 VEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFL 3600

Query: 3601 GWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEA 3660
            GWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEA
Sbjct: 3601 GWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEA 3660

Query: 3661 RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSE 3720
            RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSE
Sbjct: 3661 RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSE 3720

Query: 3721 ELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDY 3780
            ELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDY
Sbjct: 3721 ELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDY 3780

Query: 3781 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3840
            DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN
Sbjct: 3781 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3840

Query: 3841 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3900
            WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL
Sbjct: 3841 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3900

Query: 3901 LTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADR 3960
            LTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADR
Sbjct: 3901 LTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADR 3960

Query: 3961 QWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCR 4020
            QWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCR
Sbjct: 3961 QWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCR 4020

Query: 4021 ALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWH 4080
            ALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWH
Sbjct: 4021 ALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWH 4080

Query: 4081 LSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWM 4140
            LSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWM
Sbjct: 4081 LSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWM 4140

Query: 4141 GLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSL 4200
            GLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSL
Sbjct: 4141 GLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSL 4200

Query: 4201 GRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG 4260
            GRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG
Sbjct: 4201 GRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG 4260

Query: 4261 PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4302
            PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST
Sbjct: 4261 PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4302


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score = 8660 bits (22472), Expect = 0.0
 Identities = 4302/4303 (99%), Positives = 4302/4303 (99%), Gaps = 1/4303 (0%)

Query: 1    MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60
            MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
Sbjct: 1    MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60

Query: 61   PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120
            PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
Sbjct: 61   PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120

Query: 121  NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180
            NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
Sbjct: 121  NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180

Query: 181  VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240
            VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
Sbjct: 181  VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240

Query: 241  SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300
            SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV
Sbjct: 241  SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300

Query: 301  TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360
            TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE
Sbjct: 301  TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360

Query: 361  LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420
            LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY
Sbjct: 361  LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420

Query: 421  RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480
            RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP
Sbjct: 421  RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480

Query: 481  APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540
            APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD
Sbjct: 481  APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540

Query: 541  AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600
            AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR
Sbjct: 541  AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600

Query: 601  RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660
            RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC
Sbjct: 601  RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660

Query: 661  HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720
            HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD
Sbjct: 661  HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720

Query: 721  AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780
            AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
Sbjct: 721  AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780

Query: 781  LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840
            LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT
Sbjct: 781  LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840

Query: 841  NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900
            NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP
Sbjct: 841  NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900

Query: 901  WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960
            WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG
Sbjct: 901  WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960

Query: 961  SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020
            SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ
Sbjct: 961  SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020

Query: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080
            GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP
Sbjct: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080

Query: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140
            SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA
Sbjct: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140

Query: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200
            GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA
Sbjct: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200

Query: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260
            AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV
Sbjct: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260

Query: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320
            EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN
Sbjct: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320

Query: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380
            PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV
Sbjct: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380

Query: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440
            GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS
Sbjct: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440

Query: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500
            YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW
Sbjct: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500

Query: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560
            DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV
Sbjct: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560

Query: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620
            PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA
Sbjct: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620

Query: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680
            QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG
Sbjct: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680

Query: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740
            KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA
Sbjct: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740

Query: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800
            ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV
Sbjct: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800

Query: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860
            PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG
Sbjct: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860

Query: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920
            TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR
Sbjct: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920

Query: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980
            LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC
Sbjct: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980

Query: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040
            EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV
Sbjct: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040

Query: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100
            RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS
Sbjct: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100

Query: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160
            PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL
Sbjct: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160

Query: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220
            MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR
Sbjct: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220

Query: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280
            LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE
Sbjct: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280

Query: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340
            SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL
Sbjct: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340

Query: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400
            TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS
Sbjct: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400

Query: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460
            KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC
Sbjct: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460

Query: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520
            ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
Sbjct: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520

Query: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580
            HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS
Sbjct: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580

Query: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640
            ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA
Sbjct: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640

Query: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700
            QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA
Sbjct: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700

Query: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760
            ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM
Sbjct: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760

Query: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820
            RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS
Sbjct: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820

Query: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880
            DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS
Sbjct: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880

Query: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940
            DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP
Sbjct: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940

Query: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000
            YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR
Sbjct: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000

Query: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060
            WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
Sbjct: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060

Query: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120
            HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY
Sbjct: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120

Query: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180
            EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW
Sbjct: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180

Query: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240
            KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA
Sbjct: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240

Query: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300
            ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG
Sbjct: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300

Query: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360
            AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA
Sbjct: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360

Query: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAE-AFVGQMKSDLFLDDSKSLVCWPSGEGTLSW 3419
            GQQVLDIDSCLDSSVLDSSFLTFSGLHAE AFVGQMKSDLFLDDSKSLVCWPSGEGTLSW
Sbjct: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSW 3420

Query: 3420 PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG 3479
            PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG
Sbjct: 3421 PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG 3480

Query: 3480 VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG 3539
            VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG
Sbjct: 3481 VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG 3540

Query: 3540 LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF 3599
            LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF
Sbjct: 3541 LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF 3600

Query: 3600 LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE 3659
            LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE
Sbjct: 3601 LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE 3660

Query: 3660 ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS 3719
            ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS
Sbjct: 3661 ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS 3720

Query: 3720 EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD 3779
            EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD
Sbjct: 3721 EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD 3780

Query: 3780 YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH 3839
            YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH
Sbjct: 3781 YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH 3840

Query: 3840 NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP 3899
            NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP
Sbjct: 3841 NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP 3900

Query: 3900 LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD 3959
            LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD
Sbjct: 3901 LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD 3960

Query: 3960 RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC 4019
            RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC
Sbjct: 3961 RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC 4020

Query: 4020 RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW 4079
            RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW
Sbjct: 4021 RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW 4080

Query: 4080 HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW 4139
            HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW
Sbjct: 4081 HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW 4140

Query: 4140 MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS 4199
            MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS
Sbjct: 4141 MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS 4200

Query: 4200 LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR 4259
            LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR
Sbjct: 4201 LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR 4260

Query: 4260 GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4302
            GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST
Sbjct: 4261 GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4303


>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
          Length = 2459

 Score =  326 bits (836), Expect = 3e-88
 Identities = 390/1538 (25%), Positives = 647/1538 (42%), Gaps = 199/1538 (12%)

Query: 2602 QADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQ-----IRKNITE-TLVSLRV 2655
            +  P+ +++ + A+ ++LN+           +HE Q   Q     +R+ + E  L SL  
Sbjct: 889  EGGPEQLLQLAKAVSSMLNQ-----------EHESQGSGQSLSIDVRQKVREHVLGSLSA 937

Query: 2656 HT--VDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIG 2713
             T  ++D+Q++   LA+ +   RE+ CRS       + EA + +  A     TV+  A  
Sbjct: 938  VTTGLEDVQRVQE-LAEVL---REVTCRSKELTPSAQWEASLALQHASEALLTVSAKARP 993

Query: 2714 DSILN--ITGDLIHLASSDVRAPQPS--ELGAESPSRMVAS--QAYNLTSALMRILMRSR 2767
            +       T DL     S + A   +  E  AE+ S  +A+  +   +   +   L+  +
Sbjct: 994  EDQRRQAATRDLFQAVGSVLEASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGK 1053

Query: 2768 VLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAP--GPGCHFSIPEAFS-GALANLSDVVQ 2824
            +    P  LA   I     R  P S       P       F +P A S  +L    + V 
Sbjct: 1054 LPGGLPAMLATPSISVYTNRIQPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVD 1113

Query: 2825 L-IFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWA 2883
            + I     +PFP    S++ VS  V  +   + +G  IP++ L+    I + +P +S   
Sbjct: 1114 IKIMSFPKSPFPAR--SHFDVSGTVGGLRVTSPSGQLIPVKNLSEN--IEILLPRHSQ-- 1167

Query: 2884 ARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLA 2943
                 S     N  +  P+A     + ++ ++  A L +QL++           P+  L 
Sbjct: 1168 ---RHSQPTVLN--LTSPEA-----LWVNVTSGEATLGIQLHW----------RPDIALT 1207

Query: 2944 VYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGS-RDPAGSYHLNLSSHFRWS 3002
            + L     PN+ +  A   + P  +   D  P T+ +SP   R   G Y+L +       
Sbjct: 1208 LSLGYGYHPNKSSYDAQTHLVP--MVAPDELP-TWILSPQDLRFGEGVYYLTVVPESDLE 1264

Query: 3003 A-----LQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFV 3057
                  L V +  + S C ++ E    W   G      TSP Q  CL  HLT FG++  V
Sbjct: 1265 PAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLV 1324

Query: 3058 PPSHVRFVFPEPTADV------NYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAI-- 3109
              + +       TA++      N +V+ T     V Y+++     + D  D ++ +    
Sbjct: 1325 MSNAINI---HQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTVL 1381

Query: 3110 ----PFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL-DGDR-AFHRN 3163
                PF     ++ Y + V TG  RG+ T++ V + LYG+D      HL D D   F R 
Sbjct: 1382 EDNDPFA----QYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERG 1437

Query: 3164 SLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVET 3223
            ++D F ++T   LG +  +R+WHDN G  P+W++  V+V DL   R  +FL N WLS+  
Sbjct: 1438 AVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSI-- 1495

Query: 3224 EANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATC 3283
                 +++K    A++    +F  L   +   GF D HIW SI+ R  RS FTR+QR +C
Sbjct: 1496 NVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSC 1555

Query: 3284 CV-LLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILF 3342
            C  LL+C  L +   W G   D A     + ++   +   V +GL SS++++P+ L I+ 
Sbjct: 1556 CFSLLLCTMLTSIMFW-GVPKDPAEQKMDLGKIE-FTWQEVMIGLESSILMFPINLLIVQ 1613

Query: 3343 LFRMSRSKVA----------GSPSPTPAGQQVLD---------------IDSCLDSSVLD 3377
            +F+ +R +VA          GSP+ TP+ Q + D               + S   +  + 
Sbjct: 1614 IFQNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVP 1673

Query: 3378 SSFLTFSGLH---AEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLR 3434
            S  L +  ++     + +  ++  ++  ++   V W   +     P  L+  S       
Sbjct: 1674 SPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKRED-PVTLTLGSSEMKEKS 1732

Query: 3435 QLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETD 3494
            Q  + +A    GP +D       Y   +      E  ++ V   G S P      H    
Sbjct: 1733 QCPKPKAARS-GPWKDSAYRQCLYLQLEHV----EQELRLVGPRGFSQP------HSHAQ 1781

Query: 3495 LLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCA 3554
             L  L +  G     L +Q         PG  W    A+ L  +   +G     LP WC 
Sbjct: 1782 ALRQLQTLKG----GLGVQ---------PG-TWAPAHASALQVSKPPQG-----LPWWCI 1822

Query: 3555 SLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYF 3614
             +   L      VA   +   G  +    S+ WL+S + SF+ S    +PLKVL  A +F
Sbjct: 1823 LVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFF 1882

Query: 3615 SLVAKRLHPDEDDTLVESPA--VTPVSARVPRVR---------PPHGFALFLAKEEARKV 3663
            +LV KR+  DE+DT+   P   + P    + R R         PP   A+   K    K 
Sbjct: 1883 ALVLKRV-DDEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKE 1941

Query: 3664 KRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELW 3723
            ++   ++R +L Y+ FL + LL +YG       AY L   + Q   +R F  +    E +
Sbjct: 1942 QKAFALIREILAYLGFLWMLLLVAYGQRD--PSAYHLNRHL-QHSFTRGFSGVLGFREFF 1998

Query: 3724 PWMAHVLLPYVHGNQ-------SSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFS 3776
             W    L+  ++G+        +S  +G  ++RQVR+QE+  P    P+ +       +S
Sbjct: 1999 KWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSCPLAQQPQAYLNGCRAPYS 2058

Query: 3777 -----TSDYDVGWESPHNGSGTWAYSAPDLLGAWS-WGSCAVYDSGGYVQELGLSLEESR 3830
                  +DY  GW +       W Y + D    +  WG   VY  GGYV  LG   + + 
Sbjct: 2059 LDAEDMADYGEGWNA--TTLSEWQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQSTS 2116

Query: 3831 DRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALR 3890
              LR+L  + WLD  +RAVF+E T Y+  V L   VTL LE  A G      +++   L 
Sbjct: 2117 RILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSALGTFFTHAALQSLRLY 2176

Query: 3891 RLSAGLSLPLLTSVCLL--LFAVHFAVAEARTWHRE------GRWRVLRLGAWARWLLVA 3942
              + G   P + +  L+  LF +++ V + +   +E       +W +L L      +L +
Sbjct: 2177 PFTDGWH-PFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELAI----ILAS 2231

Query: 3943 LTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAA 4002
             +A    V+ A L   D Q  R  R       SF + A   +A   + A L+ L  VK  
Sbjct: 2232 WSALAVFVKRAVLAERDLQRCRNHR---EEGISFSETAAADAALGYIIAFLVLLSTVKLW 2288

Query: 4003 QQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYA 4040
              LR   + ++    L RA  ++ G  + ++ + +AY+
Sbjct: 2289 HLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYS 2326



 Score = 37.7 bits (86), Expect = 0.25
 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 30/199 (15%)

Query: 1087 VEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGV--------- 1137
            V  NV H + +PGE+ +    + +  ++T Q  V+VR  + +++V    G+         
Sbjct: 304  VSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAGPLC 363

Query: 1138 -LVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAA--------NHTYASRGTYH 1188
              V G P+ +    L    GV YT   GD +   + +Q  +          T    G   
Sbjct: 364  QAVFGDPL-WIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGPGR 422

Query: 1189 VRLEV----NNTVSGAAAQADVRVFEELRGLSVD-MSLAVEQGAPVVVSAAVQTGDNITW 1243
             RLE+    N T S  +    V + E L GL     S  +E G  ++++ ++  G     
Sbjct: 423  HRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEEL 482

Query: 1244 TFDMGDGTVLSGPEATVEH 1262
            TF+      ++G  AT  H
Sbjct: 483  TFE------VAGLNATFSH 495



 Score = 34.7 bits (78), Expect = 2.1
 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 15/126 (11%)

Query: 993  KLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVA 1052
            +L + A+ + +  T++ N+TV  +  + GLQ S     L     L +T  +   +  E+ 
Sbjct: 424  RLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEELT 483

Query: 1053 FLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFE 1112
            F    G      H+ Q  + E F +   +V                G +L+T+L  NAF 
Sbjct: 484  F-EVAGLNATFSHE-QVSFGEPFGICRLAV-------------PVEGTFLVTMLVRNAFS 528

Query: 1113 NLTQQV 1118
            NL+ ++
Sbjct: 529  NLSLEI 534


>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
            sapiens]
          Length = 1731

 Score =  179 bits (455), Expect = 4e-44
 Identities = 207/850 (24%), Positives = 360/850 (42%), Gaps = 68/850 (8%)

Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
            L + +N T L+   + S +P+  L   +YL  + +PN      +  +  + +   D   Y
Sbjct: 532  LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEE-Y 590

Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
            T+ ++P   +   G+Y++      R    Q     VSV    + C Y+   +  W + G 
Sbjct: 591  TWMLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650

Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
                +++  +  CL  HLT F +  FV P   R V  E T  +      N + +   A  
Sbjct: 651  QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707

Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
            L  Y++      K DQ D  + +           +F Y I V TG+ R + TTA V I L
Sbjct: 708  LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767

Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
            YG + RS   HL   +   F R  LD+F + T  SLG++  +R+WHDN G+SP+W++  V
Sbjct: 768  YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827

Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
            IV D+   R   FL N WL+V  +     +++  +  S   L  FR L  + +   F   
Sbjct: 828  IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885

Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
            ++WLSI  R P ++FTRIQR +CC+ L+   +  N V +  +  +        R   ++ 
Sbjct: 886  YLWLSIATRHPWNQFTRIQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944

Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
              + V + ++V+++P+ L I  LF            P    Q+ L +   + +S L  + 
Sbjct: 945  SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991

Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
             +   L A   V ++K  + FL    + +     +   S  D+     ++ S +     G
Sbjct: 992  -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050

Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
            Q  H  G  E  ++   P +    F      ++Q+ L   + +   TQ  H   D L + 
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105

Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
            S    +  E L    L     PS  +      ++   +  +  GL K     W  S+   
Sbjct: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159

Query: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619
            L       +   +           + +W++S   S L +    +P+KV+     +SL+  
Sbjct: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219

Query: 3620 ---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRLH 3667
               RL+ + + T      +   S+ VP  R  +   +++A          E   K K+L 
Sbjct: 1220 RMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKLF 1278

Query: 3668 GMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMA 3727
             +   +LV +LFL + + A Y  ++ + + + L  AI  +  S  F  I   ++ +PW  
Sbjct: 1279 KLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWAN 1335

Query: 3728 HVLLPYVHGN 3737
            H+LLP ++G+
Sbjct: 1336 HILLPSLYGD 1345



 Score = 38.1 bits (87), Expect = 0.19
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)

Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
            RF SF +  +++SAA  L    + L  V+    LR   +  V  +TL RA  E++G  L 
Sbjct: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596

Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
            +++L   YA +A  L+  C  S +    +  V   G  +      E + L P+L
Sbjct: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649


>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
          Length = 1731

 Score =  179 bits (454), Expect = 5e-44
 Identities = 206/850 (24%), Positives = 361/850 (42%), Gaps = 68/850 (8%)

Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
            L + +N T L+   + S +P+  L   +YL  + +PN  +   +  +  + +   D   Y
Sbjct: 532  LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590

Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
            T+ ++P   +   G+Y++      R    Q     VSV    + C Y+   +  W + G 
Sbjct: 591  TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650

Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
                +++  +  CL  HLT F +  FV P   R V  E T  +      N + +   A  
Sbjct: 651  QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707

Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
            L  Y++      K DQ D  + +           +F Y I V TG+ R + TTA V I L
Sbjct: 708  LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767

Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
            YG + RS   HL   +   F R  LD+F + T  SLG++  +R+WHDN G+SP+W++  V
Sbjct: 768  YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827

Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
            IV D+   R   FL N WL+V  +     +++  +  S   L  FR L  + +   F   
Sbjct: 828  IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885

Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
            ++WLSI  R P ++FTR+QR +CC+ L+   +  N V +  +  +        R   ++ 
Sbjct: 886  YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944

Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
              + V + ++V+++P+ L I  LF            P    Q+ L +   + +S L  + 
Sbjct: 945  SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991

Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
             +   L A   V ++K  + FL    + +     +   S  D+     ++ S +     G
Sbjct: 992  -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050

Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
            Q  H  G  E  ++   P +    F      ++Q+ L   + +   TQ  H   D L + 
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105

Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
            S    +  E L    L     PS  +      ++   +  +  GL K     W  S+   
Sbjct: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159

Query: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619
            L       +   +           + +W++S   S L +    +P+KV+     +SL+  
Sbjct: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219

Query: 3620 ---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRLH 3667
               RL+ + + T      +   S+ VP  R  +   +++A          E   K K+L 
Sbjct: 1220 RMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKLF 1278

Query: 3668 GMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMA 3727
             +   +LV +LFL + + A Y  ++ + + + L  AI  +  S  F  I   ++ +PW  
Sbjct: 1279 KLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWAN 1335

Query: 3728 HVLLPYVHGN 3737
            H+LLP ++G+
Sbjct: 1336 HILLPSLYGD 1345



 Score = 38.1 bits (87), Expect = 0.19
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)

Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
            RF SF +  +++SAA  L    + L  V+    LR   +  V  +TL RA  E++G  L 
Sbjct: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596

Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
            +++L   YA +A  L+  C  S +    +  V   G  +      E + L P+L
Sbjct: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649


>gi|31559825 polycystin 1-like 3 [Homo sapiens]
          Length = 1732

 Score =  178 bits (452), Expect = 9e-44
 Identities = 206/851 (24%), Positives = 360/851 (42%), Gaps = 69/851 (8%)

Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
            L + +N T L+   + S +P+  L   +YL  + +PN  +   +  +  + +   D   Y
Sbjct: 532  LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590

Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
            T+ ++P   +   G+Y++      R    Q     VSV    + C Y+   +  W + G 
Sbjct: 591  TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650

Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
                +++  +  CL  HLT F +  FV P   R V  E T  +      N + +   A  
Sbjct: 651  QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707

Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
            L  Y++      K DQ D  + +           +F Y I V TG+ R + TTA V I L
Sbjct: 708  LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767

Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
            YG + RS   HL   +   F R  LD+F + T  SLG++  +R+WHDN G+SP+W++  V
Sbjct: 768  YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827

Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
            IV D+   R   FL N WL+V  +     +++  +  S   L  FR L  + +   F   
Sbjct: 828  IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885

Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
            ++WLSI  R P ++FTR+QR +CC+ L+   +  N V +  +  +        R   ++ 
Sbjct: 886  YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944

Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
              + V + ++V+++P+ L I  LF            P    Q+ L +   + +S L  + 
Sbjct: 945  SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991

Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
             +   L A   V ++K  + FL    + +     +   S  D+     ++ S +     G
Sbjct: 992  -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050

Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
            Q  H  G  E  ++   P +    F      ++Q+ L   + +   TQ  H   D L + 
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105

Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
            S    +  E L    L     PS  +      ++   +  +  GL K     W  S+   
Sbjct: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159

Query: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619
            L       +   +           + +W++S   S L +    +P+KV+     +SL+  
Sbjct: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219

Query: 3620 RL----HPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRL 3666
            R+      +E  T      +   S+ VP  R  +   +++A          E   K K+L
Sbjct: 1220 RMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKL 1278

Query: 3667 HGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWM 3726
              +   +LV +LFL + + A Y  ++ + + + L  AI  +  S  F  I   ++ +PW 
Sbjct: 1279 FKLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWA 1335

Query: 3727 AHVLLPYVHGN 3737
             H+LLP ++G+
Sbjct: 1336 NHILLPSLYGD 1346



 Score = 38.1 bits (87), Expect = 0.19
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)

Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
            RF SF +  +++SAA  L    + L  V+    LR   +  V  +TL RA  E++G  L 
Sbjct: 1538 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1597

Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
            +++L   YA +A  L+  C  S +    +  V   G  +      E + L P+L
Sbjct: 1598 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1650


>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
            sapiens]
          Length = 1732

 Score =  178 bits (451), Expect = 1e-43
 Identities = 210/862 (24%), Positives = 368/862 (42%), Gaps = 91/862 (10%)

Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
            L + +N T L+   + S +P+  L   +YL  + +PN      +  +  + +   D   Y
Sbjct: 532  LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEE-Y 590

Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
            T+ ++P   +   G+Y++      R    Q     VSV    + C Y+   +  W + G 
Sbjct: 591  TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650

Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
                +++  +  CL  HLT F +  FV P   R V  E T  +      N + +   A  
Sbjct: 651  QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707

Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
            L  Y++      K DQ D  + +           +F Y I V TG+ R + TTA V I L
Sbjct: 708  LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767

Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
            YG + RS   HL   +   F R  LD+F + T  SLG++  +R+WHDN G+SP+W++  V
Sbjct: 768  YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827

Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
            IV D+   R   FL N WL+V  +     +++  +  S   L  FR L  + +   F   
Sbjct: 828  IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885

Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
            ++WLSI  R P ++FTRIQR +CC+ L+   +  N V +  +  +        R   ++ 
Sbjct: 886  YLWLSIATRHPWNQFTRIQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944

Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
              + V + ++V+++P+ L I  LF            P    Q+ L +   + +S L  + 
Sbjct: 945  SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991

Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
             +   L A   V ++K  + FL    + +     +   S  D+     ++ S +     G
Sbjct: 992  -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050

Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
            Q  H  G  E  ++   P +    F      ++Q+ L   + +   TQ  H   D L + 
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105

Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
            S           LQ+L EL   +  L  EQ  +  ++   ++     +        +++G
Sbjct: 1106 SQ----------LQKLQEL-LETHILPTEQEPSREVTSFAILSSEEGK------KPISNG 1148

Query: 3560 LSLLLVAVAVAVSGWVGAS-----------FPPGVSVAWLLSSSASFLASFLGWEPLKVL 3608
            LS  L +V   + G+   +                + +W++S   S L +    +P+KV+
Sbjct: 1149 LSKWLTSVCWLLLGFTSLASAFFTALYRLELSKDQATSWMISIILSVLQNIFISQPVKVV 1208

Query: 3609 LEALYFSLVAKRL----HPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA-------- 3656
                 +SL+  R+      +E  T      +   S+ VP  R  +   +++A        
Sbjct: 1209 FFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTK 1267

Query: 3657 -KEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLA 3715
              E   K K+L  +   +LV +LFL + + A Y  ++ + + + L  AI  +  S  F  
Sbjct: 1268 HPERTLKKKKLFKLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSE 1324

Query: 3716 ITRSEELWPWMAHVLLPYVHGN 3737
            I   ++ +PW  H+LLP ++G+
Sbjct: 1325 IKLLQDFYPWANHILLPSLYGD 1346



 Score = 38.1 bits (87), Expect = 0.19
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)

Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
            RF SF +  +++SAA  L    + L  V+    LR   +  V  +TL RA  E++G  L 
Sbjct: 1538 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1597

Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
            +++L   YA +A  L+  C  S +    +  V   G  +      E + L P+L
Sbjct: 1598 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1650


>gi|239745435 PREDICTED: hypothetical protein XP_002343464 [Homo
            sapiens]
          Length = 146

 Score =  168 bits (426), Expect = 9e-41
 Identities = 82/84 (97%), Positives = 83/84 (98%)

Query: 1016 MNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESF 1075
            MNRMQGL+VSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESF
Sbjct: 1    MNRMQGLRVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESF 60

Query: 1076 PVPDPSVAQVLVEHNVMHTYAAPG 1099
            PVPDPSVAQVLVEHNV HTYAAPG
Sbjct: 61   PVPDPSVAQVLVEHNVTHTYAAPG 84


>gi|4505835 polycystin 2 [Homo sapiens]
          Length = 968

 Score =  122 bits (305), Expect = 1e-26
 Identities = 103/421 (24%), Positives = 178/421 (42%), Gaps = 25/421 (5%)

Query: 3655 LAKEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAY-RLQSAI-----KQEL 3708
            + +    + K L  +LR L+ Y+LFL+V  + +YG  S + + Y R+ S +       + 
Sbjct: 206  MEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKT 265

Query: 3709 HSRAFLAITRSEELWPWMAHVLLPYVH-----GNQSSPE-----------LGPPRLRQVR 3752
                F  ++  E+ W +    LL  ++      NQ+  +           LG PR+RQ+R
Sbjct: 266  EKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLR 325

Query: 3753 LQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWESPHNGSGTWAY-SAPDLLGAWSWGSCA 3811
            ++      P   R         +S S  D     P NG+  W Y S  DL G+  WG  A
Sbjct: 326  VRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGT-AWIYTSEKDLNGSSHWGIIA 384

Query: 3812 VYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLE 3871
             Y   GY  +L  + EE+  ++  L+ + WLD  +RA F++ + Y+  + L   V L +E
Sbjct: 385  TYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVE 444

Query: 3872 FPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREGRWRVLR 3931
            FPA G  + +   +P  L R        L     +  F + + V E     R  +    R
Sbjct: 445  FPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFR 504

Query: 3932 LGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAA 3991
               W    +V +  +   + +     ++ +           F +F+ +A        +AA
Sbjct: 505  -SFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAA 563

Query: 3992 SLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCV 4051
              +F + +K  + + F R  S    T+ R   +L G  +   ++ +AYAQLA L+  + V
Sbjct: 564  VTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQV 623

Query: 4052 D 4052
            D
Sbjct: 624  D 624


>gi|19923084 polycystin-1L1 [Homo sapiens]
          Length = 2849

 Score =  121 bits (303), Expect = 2e-26
 Identities = 99/367 (26%), Positives = 163/367 (44%), Gaps = 39/367 (10%)

Query: 2993 LNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFG 3052
            +N + HF+W             C ++ + +  W++E   P   TSP +  C    L AF 
Sbjct: 1680 VNYTVHFQWIR-----------CLFWDKRE--WKSERFSPQPGTSPEKVNCSYHRLAAFA 1726

Query: 3053 -------ASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASR 3105
                   AS  V         PE     N +  +     ++ Y  + A   ++D  +  +
Sbjct: 1727 LLRRKLKASFEVSDISKLQSHPE-----NLLPSIFIMGSVILYGFLVAKSRQVDHHEKKK 1781

Query: 3106 GRAIPF--CGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA--FH 3161
               I        G   Y +++ TG+   +  T+ V I+L G +  S  + L       F 
Sbjct: 1782 AGYIFLQEASLPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFE 1841

Query: 3162 RNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSV 3221
            RNS   F ++ P  LG + KIR+WHD++G SP WF+ HV+V++L T +  FF    WLS 
Sbjct: 1842 RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS- 1900

Query: 3222 ETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRA 3281
                + G VE+E+        L FR+L   +      D H+WLS++ RP  SR+    R 
Sbjct: 1901 -AGRHDGRVERELTCLQGG--LGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRL 1957

Query: 3282 TCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAIL 3341
            T    L+C++    A+    V        H+  +SP ++ +  VGL+ +++  P    + 
Sbjct: 1958 TVSFSLLCVYACLTAL----VAAGGQEQPHLD-VSP-TLGSFRVGLLCTLLASPGAQLLS 2011

Query: 3342 FLFRMSR 3348
             LFR+S+
Sbjct: 2012 LLFRLSK 2018



 Score = 85.1 bits (209), Expect = 1e-15
 Identities = 97/373 (26%), Positives = 154/373 (41%), Gaps = 26/373 (6%)

Query: 1938 HSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQ 1997
            H FP +  + VS   +  V  +QA   + V   +  + V        AT T+  FTA  +
Sbjct: 473  HHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTV-FATDTDITFTAVTK 531

Query: 1998 RGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSE-NRTLVLE 2056
                + + WYF       D  V  + R +           + V+A N + S  +   V+ 
Sbjct: 532  ETIPLEFEWYFG-----EDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIR 586

Query: 2057 VQDAVQYVALQS-GPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSYL 2115
            VQ  +    L S      N S  FE   +     VAY WDFGDG+    +    + H Y 
Sbjct: 587  VQKKIVANRLTSPSSALVNASVAFECWINFGTD-VAYLWDFGDGTVSLGSSS--SSHVYS 643

Query: 2116 RPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQ--RNYLEAHV 2173
            R G++ V+V A N VS    +  + +    C+ P V  + P +V + RSQ  R  +    
Sbjct: 644  REGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEA 703

Query: 2174 DLRDCVTYQTEYRWEVYRTASCQRPGRPARVALP-GVDVSRPRLVLPRLALPVGHYCFVF 2232
             +   ++    Y W +         G P  V+LP  VD  R  L+LP   L  G+Y  + 
Sbjct: 704  AVFCDISQGLSYTWNL-----MDSEGLP--VSLPAAVDTHRQTLILPSHTLEYGNYTALA 756

Query: 2233 VVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRD--LVLDGSESYDPNLEDGD 2290
             V    + +  +    + V  +  V +I  G++  +S T    +VL G++S+DP   D  
Sbjct: 757  KVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRTTSSPIVLRGTQSFDP---DDP 813

Query: 2291 QTPLSFHWACVAS 2303
               L +HW C  +
Sbjct: 814  GATLRYHWECATA 826



 Score = 73.9 bits (180), Expect = 3e-12
 Identities = 139/592 (23%), Positives = 213/592 (35%), Gaps = 102/592 (17%)

Query: 3548 LLPAWCASLAHGLSLLLVAVAVAVS-------GWVGASFPPGVSVAWLLSSSASFLASFL 3600
            L+P W  +L    S  + A+    S       G++   F     V WL   S S +    
Sbjct: 2121 LMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIF 2180

Query: 3601 GWEPLKVLLEALYFSLVAK-----------RLHPDEDDTLVE----------SPAVTPVS 3639
              +PL V L AL F+   +               D D  L E          S ++   +
Sbjct: 2181 ITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCSIPDCA 2240

Query: 3640 ARVPRV-------------RPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLA 3686
              V +V              PP    L   ++  R+  R    LR + + +L LL+ L  
Sbjct: 2241 GEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLLLLLCV 2300

Query: 3687 SYGDASCHGHAYRLQSAIKQEL--HSRAFLAITRS-EELWPWMAHVLLP--YVHGNQSSP 3741
             YG  S     Y L  AI++E   ++R  L   R+  + W W    LL   Y  G  S+ 
Sbjct: 2301 IYGRFS--QDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLYPGGTPSAR 2358

Query: 3742 E--------------LGPPRLRQVRLQEALYPDPPGP-------RVHTCSAAGGFSTSDY 3780
                           +G   +RQ+++       PP P        + TCS   G   + Y
Sbjct: 2359 VPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEVGGPENPY 2418

Query: 3781 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3840
             +    P N + T   + P        G C   +    V  LG +  E+   L  L+   
Sbjct: 2419 LI---DPENQNVT--LNGP--------GGCGTRED--CVLSLGRTRTEAHTALSRLRASM 2463

Query: 3841 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3900
            W+D  +RAV +  T Y+P   L  +V+LR+E    G  + +  V  F++ R  + L   L
Sbjct: 2464 WIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL 2523

Query: 3901 LTS--VCLLLFAVHFAVAEARTWHRE--GRWRVLRLGAWARWLLVALTAATALVRLAQLG 3956
            +    V L L  +H  V   R   +     WR  R   W    +V ++     V    + 
Sbjct: 2524 MLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPR--NWLELSVVGVSLTYYAVSGHLVT 2581

Query: 3957 AADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGK 4016
             A     +F RG  R F     +A  +  AR L   LLFL  +K           +    
Sbjct: 2582 LAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS 2641

Query: 4017 TLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGT 4068
             +  +LP +    L   ++  A + L   L+     S+W       VL PGT
Sbjct: 2642 MMRHSLPSIFVAGLVGALMLAALSHLHRFLL-----SMW-------VLPPGT 2681



 Score = 61.6 bits (148), Expect = 2e-08
 Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 20/232 (8%)

Query: 1313 LTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFT 1372
            ++A++  +  H      F D   N   +    V H+F    ++ ++ +  ++V  +  + 
Sbjct: 442  VSAFMNSSSVHEDEVLVFADSQVN---QKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWH 498

Query: 1373 SICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVT 1432
            S+ V  ++ +V++           +    A      P  + W FG  E  P R     + 
Sbjct: 499  SMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFG--EDPPVRTTSRSIK 556

Query: 1433 FIYRDPGSYLVTVTASNNISAA-NDSALVEVQEPVLV------TSIKVNGSLGLELQQPY 1485
                 P  Y V V ASN +S+  ++  ++ VQ+ ++       +S  VN S+  E     
Sbjct: 557  KRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPSSALVNASVAFECW--- 613

Query: 1486 LFSAVGRGRPASYLWDLGDGG-WLEGPEVTHAYNSTGDFTVRVAGWNEVSRS 1536
                +  G   +YLWD GDG   L     +H Y+  G+FTV V  +N VS S
Sbjct: 614  ----INFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS 661



 Score = 46.2 bits (108), Expect = 7e-04
 Identities = 73/328 (22%), Positives = 126/328 (38%), Gaps = 46/328 (14%)

Query: 1513 VTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSL 1572
            V H + S   + V      +V  S+AW ++TV  +++ + V  + TV   +  ++F+   
Sbjct: 471  VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530

Query: 1573 EAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGT-------FNIIVTAENEVGSAQDSIF 1625
            +    + + W   +        P +  T RS+         + ++V A N + S      
Sbjct: 531  KETIPLEFEWYFGE-------DPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPH 583

Query: 1626 VYVLQLIEGLQVVGGGRYFPT----NHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSGK 1681
            V  +Q     ++V      P+    N +V  +  +  GT+V+Y W    D G      G 
Sbjct: 584  VIRVQ----KKIVANRLTSPSSALVNASVAFECWINFGTDVAYLW----DFGDGTVSLGS 635

Query: 1682 GFSLTVL-EAGTYHVQLRATNMLGSA---------WADCTMDFVEPVGWLMVAA-SPNPA 1730
              S  V    G + V++ A N + ++            C    V+ +G   V      P 
Sbjct: 636  SSSSHVYSREGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPV 695

Query: 1731 AVNTSVTLSAELAGGSGVVYTWSL--EEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLG 1788
             +  +   +       G+ YTW+L   EGL         TH   T  L   T+  GN   
Sbjct: 696  RLGVTFEAAVFCDISQGLSYTWNLMDSEGLPVSLPAAVDTHR-QTLILPSHTLEYGN--Y 752

Query: 1789 SANATVEVDVQVPVS----GLSIRASEP 1812
            +A A V+++  V  S    GL +RA  P
Sbjct: 753  TALAKVQIEGSVVYSNYCVGLEVRAQAP 780



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 21/223 (9%)

Query: 1091 VMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYP-- 1148
            V+H + +   Y ++ ++     +      ++V   + SV+V  +  V      +TF    
Sbjct: 471  VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530

Query: 1149 -HPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADV- 1206
               +P    + + W FG+  PV T S+         +  Y V ++ +N +S   ++  V 
Sbjct: 531  KETIP----LEFEWYFGEDPPVRTTSRSIKKRLSIPQW-YRVMVKASNRMSSVVSEPHVI 585

Query: 1207 RVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEHVYLR 1266
            RV +++    +    +    A V     +  G ++ + +D GDGTV  G  ++  HVY R
Sbjct: 586  RVQKKIVANRLTSPSSALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSS-SHVYSR 644

Query: 1267 AQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQP 1309
                TV V A +     A +L   +F++         C P QP
Sbjct: 645  EGEFTVEVLAFNNVS--ASTLRQQLFIV---------CEPCQP 676



 Score = 38.9 bits (89), Expect = 0.11
 Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 36/199 (18%)

Query: 992  FKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEV 1051
            +++ + ASN +S+V    +V   R+ +       T P+    NA++A    +  +   +V
Sbjct: 565  YRVMVKASNRMSSVVSEPHVI--RVQKKIVANRLTSPSSALVNASVAFECWI--NFGTDV 620

Query: 1052 AFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASN-- 1109
            A+LW FGDG  +L                         +  H Y+  GE+ + VLA N  
Sbjct: 621  AYLWDFGDGTVSLG----------------------SSSSSHVYSREGEFTVEVLAFNNV 658

Query: 1110 AFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRP------VTFYPHPL-PSPGGVLYTWD 1162
            +   L QQ+ +      P +   +  G +   R       VTF          G+ YTW+
Sbjct: 659  SASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWN 718

Query: 1163 FGDGSPVLTQSQPAANHTY 1181
              D S  L  S PAA  T+
Sbjct: 719  LMD-SEGLPVSLPAAVDTH 736


>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
          Length = 805

 Score =  110 bits (276), Expect = 2e-23
 Identities = 105/416 (25%), Positives = 179/416 (43%), Gaps = 43/416 (10%)

Query: 3670 LRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSR-------AFLAITRSEEL 3722
            LR LLVY++FL+   L +YG  S   + Y   + +  EL          +F AI+   + 
Sbjct: 101  LRELLVYIVFLVDICLLTYGMTSSSAYYY---TKVMSELFLHTPSDTGVSFQAISSMADF 157

Query: 3723 WPWMAHVLLPYV------------HGNQS-----SPELGPPRLRQVRLQEALYPDPPGPR 3765
            W +    LL  +            HG+ S     +  LG PRLRQ++++          R
Sbjct: 158  WDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFR 217

Query: 3766 VHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGAWS-WGSCAVYDSGGYVQELGL 3824
                S    +S    +     P NG+  W Y + D LG +S WG    Y  GGY  +L  
Sbjct: 218  EDILSCYDVYSPDKEEQLPFGPFNGTA-WTYHSQDELGGFSHWGRLTSYSGGGYYLDLPG 276

Query: 3825 SLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSV 3884
            S + S + LR LQ   WLD  +R VF++ + Y+  + L   + L +EFPA G A+ +  +
Sbjct: 277  SRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQI 336

Query: 3885 RPFALRRLSAGLSLPLL-TSVCLLLFAVHFAVAEA------RTWHREGRWRVLRLGAWAR 3937
            R   L R  +     ++   V   +F  ++ V E       R  +    W +L L     
Sbjct: 337  RTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDL----- 391

Query: 3938 WLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLL 3997
             +++ L+       + +    +R   + ++ +P  +  F+ +A   +    + A  LF  
Sbjct: 392  -VVILLSIVAVGFHIFRTLEVNRLMGKLLQ-QPNTYADFEFLAFWQTQYNNMNAVNLFFA 449

Query: 3998 LVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDS 4053
             +K  + + F +  +    TL R   ++LG  +   ++  AYAQL  LL  + V++
Sbjct: 450  WIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVEN 505


>gi|5174633 receptor for egg jelly-like protein precursor [Homo
            sapiens]
          Length = 2253

 Score =  103 bits (256), Expect = 5e-21
 Identities = 128/558 (22%), Positives = 217/558 (38%), Gaps = 77/558 (13%)

Query: 3548 LLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKV 3607
            +LP WC  +A  L     +++     + G ++    S+ WL +S  SF  S L  +P K+
Sbjct: 1571 VLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKI 1630

Query: 3608 LLEALY---------------------FSLVAKRLHPDEDDTLVESPAVTPVSARVPRVR 3646
            +L + +                       L   R+HP+E   + +      V  R  R+ 
Sbjct: 1631 ILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQI----VRIRGTRMY 1686

Query: 3647 PPHGFALFLAKEEARKVKRLHGMLRSLLVYM---------LFLLVTLLASYGDASCHGHA 3697
             P      L ++E R  KR   + R  L+++         L LL+ L+       C  + 
Sbjct: 1687 QP------LTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN 1740

Query: 3698 YRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGN--------QSSPELGPPRLR 3749
              ++     +L +     +T+ E+++ W+  VLLP +H +         SS  LG P +R
Sbjct: 1741 QFIRDRFSMDLAT-----VTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMR 1795

Query: 3750 QVRLQEALYPDPPGPR-VHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGA---- 3804
            QVR + +     P  + V             Y +  E   N SG W       +      
Sbjct: 1796 QVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNG 1855

Query: 3805 ------------WSWGSCAVYDSGGYVQELGLSLEESRD----RLRFLQLHNWLDNRSRA 3848
                        +S+G    Y SGGY   L    E+ R     RL+ LQ  NWLD ++ A
Sbjct: 1856 FTYKPQGTQWLYYSYGLLHTYGSGGYA--LYFFPEQQRFNSTLRLKELQESNWLDEKTWA 1913

Query: 3849 VFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLL 3908
            V LELT ++P + L  ++++  E    G    ++S+  F+L       S  +   V +L+
Sbjct: 1914 VVLELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILI 1973

Query: 3909 FAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRG 3968
            F + + V E     +E    V  +     + L  +     ++ L +   A     RF   
Sbjct: 1974 FFLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLA-TGIIRFYLS 2032

Query: 3969 RPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGV 4028
             P  F  F  V+Q+    R +   LLFL ++K  +  RF     +  + +  ALP +  +
Sbjct: 2033 NPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHM 2092

Query: 4029 TLGLVVLGVAYAQLAILL 4046
               + V    Y     L+
Sbjct: 2093 AFVVSVYFFVYMAFGYLV 2110



 Score =  100 bits (249), Expect = 3e-20
 Identities = 74/285 (25%), Positives = 125/285 (43%), Gaps = 21/285 (7%)

Query: 3074 NYIVMLTCAVCLVTYMVMAAILHKLDQLDAS-RGRAI--PFCGQRGRFKYEILVKTGWGR 3130
            N + + T    ++ Y+ +A      D++D   RG  I  P         Y + + TG   
Sbjct: 1183 NPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRW 1242

Query: 3131 GSGTTAHVGIMLYGVDSRS-----GHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVW 3185
            GSGT A+V + L G  S S      H H       +R S++ F + T   LG +  IRVW
Sbjct: 1243 GSGTRANVFVQLRGTVSTSDVHCLSHPHFT---TLYRGSINTFLLTTKSDLGDIHSIRVW 1299

Query: 3186 HDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRF 3245
            H+N+G SP+W+L  + V +L +     F+   WLSV+T      +++          L  
Sbjct: 1300 HNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDT-----TLDRTFHVTHPDERLTR 1354

Query: 3246 RRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDS 3305
            +     ++       H+W SI+       F R+QR +CC+ ++   L  N +++      
Sbjct: 1355 KDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQE 1414

Query: 3306 AYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSK 3350
               +     +      ++ +G+ S ++  PV L I FLF  S+ K
Sbjct: 1415 QTESRERKYMR-----SMMIGIESVLITIPVQLLITFLFTCSQRK 1454



 Score = 72.0 bits (175), Expect = 1e-11
 Identities = 141/625 (22%), Positives = 243/625 (38%), Gaps = 80/625 (12%)

Query: 2100 SPGQDTDEPRAEHSYLR------PGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDV 2153
            SP      PR +  ++        G  RV + A N  S    +++V+ Q+ AC    V +
Sbjct: 163  SPRSAAPGPRPQQGFVARTECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRI 222

Query: 2154 VL-----PLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASC-QRPGRPARVALP 2207
                   P+++ M+      + A V L           W+V+   +  Q P     + LP
Sbjct: 223  NTDQKGAPVRLSMQAEAT--INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLP 280

Query: 2208 GVDVSRPRLVL--PRLALPVGHYCFVFVVSF--GDTPLTQ---SIQANVTVAPERLVPII 2260
             +++    L +  P  +L  G Y F F VS   G+  + +   S    V +    L  ++
Sbjct: 281  QLEIRNSPLFIHIPNNSLQWGVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVM 340

Query: 2261 EGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPR-- 2318
             G +    + T  L+LDGS S DP+  D     L F W C  +  R  GG  +  G +  
Sbjct: 341  LGDANITANFTEQLILDGSTSSDPD-ADSPLQGLQFFWYC-TTDPRNYGGDRIILGSKEV 398

Query: 2319 -------------GSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPI 2365
                             +T+  E L     Y F + + K  R    +++ V +  G   I
Sbjct: 399  CHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVIRKDSR-TAFSDKRVHVLQGPKAI 457

Query: 2366 VSLECV-SCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLD-ETTTS 2423
              + C+ +C+   +     S ++     C NC+S     +W+  + S   ++ D    T 
Sbjct: 458  AHITCIENCERNFIVSDRFSLFL----NCTNCASRDFY-KWSILSSSGGEMLFDWMGETV 512

Query: 2424 TGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASI---RLSPNRPPLGGSCRLFP 2480
            TG  G  L ++    R      F++++        G  S+       N  P  G C++ P
Sbjct: 513  TGRNGAYLSIKAFAFRHFLEAEFSISLYLACW--SGVTSVFRHSFIINHGPQIGECKINP 570

Query: 2481 LGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSY----- 2535
               + AL TK   +C+ + D      PL Y +++        E   V + +L +      
Sbjct: 571  AKGI-ALITKFVVQCSNFRDKH---VPLTYKIIVSDLHSVG-EISSVKENTLGTILYLGP 625

Query: 2536 GAVLPPGFRP----HFEVGLAVVVQ--DQLGAAVVALNRSLAITLPEPNGSATGLTVWLH 2589
             + +PP F P      + GL +  Q  D LGA       + A    + N S T L   L 
Sbjct: 626  QSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNSSKTVLNQLLS 685

Query: 2590 GLT--ASVLPGLLRQAD--PQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKN 2645
                 +S+L  L+++ D  P   + Y +A  +VLN  +  L +       R  R  +RK+
Sbjct: 686  FTVGPSSLLSTLIQKKDFLPAGYLLYIVA--SVLNNMKTELPL-------RDDRVNLRKH 736

Query: 2646 ITETLVSLRVHTVDDIQQIAAALAQ 2670
            + +    L V T+ +I Q+   + +
Sbjct: 737  LIDQSFLLPVSTLVEIGQVVMTITK 761


>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
          Length = 613

 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 92/429 (21%), Positives = 170/429 (39%), Gaps = 51/429 (11%)

Query: 3661 RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYR-------LQSAIKQELHSRAF 3713
            RK   +   L+ LL+Y +FL+   + ++G  + H +          L +++  E  +  F
Sbjct: 20   RKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTN-F 78

Query: 3714 LAITRSEELWPWMAHVLLPYVH-----GNQSSPEL-------------GPPRLRQVRLQE 3755
             +I    + W +M   LL  ++      NQ    L             G PR+RQ+++  
Sbjct: 79   KSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKV-- 136

Query: 3756 ALYPDPPGPRVHTCSAAGGFST------SDYDVGWESPHNG----SGTWAYSAPDLLGAW 3805
                     R +TC     F +        Y    E   N     +  W YS  +    W
Sbjct: 137  ---------RNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNTNSPW 187

Query: 3806 SWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAA 3865
             WG   VY +GGY+  L  S  E++++   L+L++W+   +R +F++ + Y+  V L   
Sbjct: 188  HWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCI 247

Query: 3866 VTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREG 3925
            + L  EFPA G  L   S + ++++ L          + C + F +   V   +   +  
Sbjct: 248  IRLVAEFPATGGILT--SWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIK 305

Query: 3926 RWRVLRLGAWARW--LLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLS 3983
             ++     +   W  LL+ L    A+                +     +++ F  +A   
Sbjct: 306  EFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWH 365

Query: 3984 SAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLA 4043
                 + A  +F   +K  + + F +  S    TL R + +++G  +   ++  AYAQL 
Sbjct: 366  IYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLG 425

Query: 4044 ILLVSSCVD 4052
             L+  S VD
Sbjct: 426  FLVFGSQVD 434


>gi|194306623 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 81.3 bits (199), Expect = 2e-14
 Identities = 41/101 (40%), Positives = 56/101 (55%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
           L ++HN L +L    L  L  L  L I+NN++ TL  G F  L  LS + L  NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187

Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
           GL WL  WA   +V + +P++  CA P +L G P+  +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228


>gi|194306621 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 81.3 bits (199), Expect = 2e-14
 Identities = 41/101 (40%), Positives = 56/101 (55%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
           L ++HN L +L    L  L  L  L I+NN++ TL  G F  L  LS + L  NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187

Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
           GL WL  WA   +V + +P++  CA P +L G P+  +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228


>gi|39930401 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 81.3 bits (199), Expect = 2e-14
 Identities = 41/101 (40%), Positives = 56/101 (55%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
           L ++HN L +L    L  L  L  L I+NN++ TL  G F  L  LS + L  NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187

Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
           GL WL  WA   +V + +P++  CA P +L G P+  +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228


>gi|194306618 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 81.3 bits (199), Expect = 2e-14
 Identities = 41/101 (40%), Positives = 56/101 (55%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
           L ++HN L +L    L  L  L  L I+NN++ TL  G F  L  LS + L  NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187

Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
           GL WL  WA   +V + +P++  CA P +L G P+  +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
          Length = 2211

 Score = 78.2 bits (191), Expect = 2e-13
 Identities = 41/104 (39%), Positives = 66/104 (63%), Gaps = 4/104 (3%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLG 3177
            YE++  TG  RG+GT A+V I L+G +  S    L      AF + ++D+FR+ T +++G
Sbjct: 45   YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRT-NNVG 103

Query: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVRDLQTAR-SAFFLVNDWLS 3220
             ++K+R+ HDN GL+ +W+L HVIV D++      +F  N+WLS
Sbjct: 104  LIYKVRIEHDNTGLNASWYLDHVIVTDMKRPHLRYYFNCNNWLS 147



 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 52/161 (32%), Positives = 79/161 (49%), Gaps = 7/161 (4%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD---RAFHRNSLDIFRIATPHSL 3176
            Y + VKT    G+GT A+V I+++G +  SG   L        F RN+ D F      SL
Sbjct: 1825 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 1884

Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLA 3236
            G + K+RVWHDNKG+ P W L +V V+D     +  F  + WLS ++E +G  V     A
Sbjct: 1885 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS-KSEGDGQTVRDFACA 1943

Query: 3237 AS---DAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSR 3274
             +   D        +++     G   +++WL +  R  RS+
Sbjct: 1944 NNKICDELEETTYEIVIETGNGGETRENVWLILEGRKNRSK 1984



 Score = 73.2 bits (178), Expect = 5e-12
 Identities = 41/118 (34%), Positives = 68/118 (57%), Gaps = 4/118 (3%)

Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLG 3177
            KYE+ V TG   G+GT A V I ++G    +G R L+ ++  F + + D F +  P  LG
Sbjct: 173  KYEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEKDNFEKGAEDRFILDAP-DLG 231

Query: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVL 3235
             + KI V H+NKG S  WFL  +++ D+   R   F +N WL+++ +   G +++++L
Sbjct: 232  QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDED--DGKIQRDIL 287



 Score = 66.2 bits (160), Expect = 7e-10
 Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 6/115 (5%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA----FHRNSLDIFRIATPHS 3175
            + + +KTG  + +GT A+V I L+G    +G   L   +     F R+S++IF + T   
Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETL-D 1235

Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLV 3230
            LG +WK+R+ HDN G +P WF+  V V      +   F    WL+ + E +G ++
Sbjct: 1236 LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLA-KNEDDGSII 1289



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 3/103 (2%)

Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIATPHSL 3176
            KYE++V TG+  G+GT A+V + ++G +  +G R L       F R S D F + T   L
Sbjct: 2093 KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LEL 2151

Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWL 3219
            G + K+R+ HD+ G    W ++ V V +  T  +  F    WL
Sbjct: 2152 GELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 2194



 Score = 61.6 bits (148), Expect = 2e-08
 Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 7/131 (5%)

Query: 3117 RFKYEILVKTGWGRGSGTTAHVGIMLYGVD-SRSGHRHL---DGDRAFHRNSLDIFRIAT 3172
            R  YE+ V TG    +GT A+V + +YG +   +G R L   D    F +   D F I  
Sbjct: 1021 RNTYEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA 1080

Query: 3173 PHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEK 3232
               LG++ KIR+ HDN G    WFL  + + D+    + +F    WL+VE +   G + +
Sbjct: 1081 I-DLGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEED--DGQLSR 1137

Query: 3233 EVLAASDAALL 3243
            E+L   ++ +L
Sbjct: 1138 ELLPVDESYVL 1148



 Score = 57.4 bits (137), Expect = 3e-07
 Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLGS 3178
            YE+ V TG   G GT +++ + LYG++  +    LD  +A F R   D F I     +  
Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKARFEREQNDTF-IMEILDIAP 1756

Query: 3179 VWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLS 3220
              K+R+  D  G  P WFL+ ++++++ T     F   DWLS
Sbjct: 1757 FTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798



 Score = 55.5 bits (132), Expect = 1e-06
 Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 11/161 (6%)

Query: 3116 GRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDR----AFHRNSLDIFRIA 3171
            G  +Y + V TG   G+GT A+V + L+G    +G R L   R     F + + D F I 
Sbjct: 551  GMARYHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIE 610

Query: 3172 TPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARS--AFFLVNDWLSVETEANGGL 3229
            +  ++ +V ++R+ HD KG    W+L  V+VR+     S    F    WL  + + +G L
Sbjct: 611  SV-TMRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKDKD-DGQL 668

Query: 3230 VEKEVLAASDAALLRFR---RLLVAELQRGFFDKHIWLSIW 3267
            V + + + S A L  FR    L   ++     D  +++ ++
Sbjct: 669  VRELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLY 709



 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 8/131 (6%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGV--DSRSGHRHLDGDRAFHRNSLDIFRIATPHSLG 3177
            Y + V TG  RG+GT + + +++YG   +  SG   L+G   F R   DIF I     L 
Sbjct: 298  YIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIFLEGG-VFDRGRTDIFHIELAVLLS 356

Query: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAA 3237
             + ++ V H N G++  WF + V++    T     F  ++WL  E +A+ GL+E+++   
Sbjct: 357  PLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNWLD-EKKAD-GLIERQLY-- 412

Query: 3238 SDAALLRFRRL 3248
             +   LR +RL
Sbjct: 413  -EMVSLRKKRL 422



 Score = 53.5 bits (127), Expect = 4e-06
 Identities = 30/92 (32%), Positives = 52/92 (56%), Gaps = 7/92 (7%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDG-DRAFHRNSLDIFRIATPHSLGS 3178
            YE+ + TG   G+GT+A V + +YG   ++    L    + F R S D F++     +G 
Sbjct: 816  YEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSKVFERASKDTFQLEAA-DVGE 874

Query: 3179 VWKIRVWHDNKGLSPAWF-----LQHVIVRDL 3205
            V+K+R+ H  +G  P+WF     L+H++VR++
Sbjct: 875  VYKLRLGHTGEGFGPSWFVDTVWLRHLVVREV 906



 Score = 51.6 bits (122), Expect = 2e-05
 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 5/109 (4%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL----DGDRAFHRNSLDIFRIATPHS 3175
            Y + + TG   G+GT A V I +YG    +G R+L    +    F R + D F I     
Sbjct: 1462 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEAA-D 1520

Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETE 3224
            LG ++KI++ HDN      W+++ V + +        FL   WLS++ E
Sbjct: 1521 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKE 1569



 Score = 50.4 bits (119), Expect = 4e-05
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 7/117 (5%)

Query: 3118 FKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL---DGDRA--FHRNSLDIFRIAT 3172
            F+Y I +KTG   G+ T + V I LYG  S +  + L   D +    F R  +D F + T
Sbjct: 684  FRYHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVLLVSDNNLKDYFERGRVDEFTLET 743

Query: 3173 PHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGL 3229
             + +G++ ++ + HD+ G+  +WFL  V +R  +  +   F  N WL  + +A+G L
Sbjct: 744  LN-IGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGKQYTFPANRWLD-KNQADGRL 798



 Score = 50.1 bits (118), Expect = 5e-05
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)

Query: 3117 RFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLD-GDRAFHRNSLDIFRIATPHS 3175
            +F + + V T   + +GT + + I +YG   R+    L+  ++ F    ++ FRI  P  
Sbjct: 424  KFPWSLWVWTTDLKKAGTNSPIFIQIYGQKGRTDEILLNPNNKWFKPGIIEKFRIELP-D 482

Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEAN 3226
            LG  +KIRVWHD +     W L+ + + +        F  N WL    + N
Sbjct: 483  LGRFYKIRVWHDKRSSGSGWHLERMTLMNTLNKDKYNFNCNRWLDANEDDN 533



 Score = 45.4 bits (106), Expect = 0.001
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL------DGDRAFHRNSLDIFRIATP 3173
            YEI + T     +GT A++ I++YG D+    +        +  + F R S   F +   
Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 1367

Query: 3174 HSLGSVWKIRVWHDNKGLSPAWFLQHVIVR----DLQTARSAFFLVNDWLSVETE 3224
                 + KIR+ H+N G++P W   HV +R    D   A +  F  + WL+   +
Sbjct: 1368 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSED 1422


>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sapiens]
          Length = 1114

 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 52/161 (32%), Positives = 79/161 (49%), Gaps = 7/161 (4%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD---RAFHRNSLDIFRIATPHSL 3176
            Y + VKT    G+GT A+V I+++G +  SG   L        F RN+ D F      SL
Sbjct: 776  YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 835

Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLA 3236
            G + K+RVWHDNKG+ P W L +V V+D     +  F  + WLS ++E +G  V     A
Sbjct: 836  GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS-KSEGDGQTVRDFACA 894

Query: 3237 AS---DAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSR 3274
             +   D        +++     G   +++WL +  R  RS+
Sbjct: 895  NNKICDELEETTYEIVIETGNGGETRENVWLILEGRKNRSK 935



 Score = 66.2 bits (160), Expect = 7e-10
 Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 6/115 (5%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA----FHRNSLDIFRIATPHS 3175
            + + +KTG  + +GT A+V I L+G    +G   L   +     F R+S++IF + T   
Sbjct: 66   FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETL-D 124

Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLV 3230
            LG +WK+R+ HDN G +P WF+  V V      +   F    WL+ + E +G ++
Sbjct: 125  LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLA-KNEDDGSII 178



 Score = 57.4 bits (137), Expect = 3e-07
 Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLGS 3178
            YE+ V TG   G GT +++ + LYG++  +    LD  +A F R   D F I     +  
Sbjct: 649  YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKARFEREQNDTF-IMEILDIAP 707

Query: 3179 VWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLS 3220
              K+R+  D  G  P WFL+ ++++++ T     F   DWLS
Sbjct: 708  FTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749



 Score = 51.6 bits (122), Expect = 2e-05
 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 5/109 (4%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL----DGDRAFHRNSLDIFRIATPHS 3175
            Y + + TG   G+GT A V I +YG    +G R+L    +    F R + D F I     
Sbjct: 351  YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEAA-D 409

Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETE 3224
            LG ++KI++ HDN      W+++ V + +        FL   WLS++ E
Sbjct: 410  LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKE 458



 Score = 45.4 bits (106), Expect = 0.001
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL------DGDRAFHRNSLDIFRIATP 3173
            YEI + T     +GT A++ I++YG D+    +        +  + F R S   F +   
Sbjct: 197  YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 256

Query: 3174 HSLGSVWKIRVWHDNKGLSPAWFLQHVIVR----DLQTARSAFFLVNDWLSVETE 3224
                 + KIR+ H+N G++P W   HV +R    D   A +  F  + WL+   +
Sbjct: 257  DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSED 311



 Score = 40.0 bits (92), Expect = 0.050
 Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 2/56 (3%)

Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIAT 3172
            KYE++V TG+  G+GT A+V + ++G +  +G R L       F R S D F + T
Sbjct: 1044 KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET 1099


>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sapiens]
          Length = 512

 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 52/161 (32%), Positives = 79/161 (49%), Gaps = 7/161 (4%)

Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD---RAFHRNSLDIFRIATPHSL 3176
            Y + VKT    G+GT A+V I+++G +  SG   L        F RN+ D F      SL
Sbjct: 126  YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 185

Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLA 3236
            G + K+RVWHDNKG+ P W L +V V+D     +  F  + WLS ++E +G  V     A
Sbjct: 186  GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS-KSEGDGQTVRDFACA 244

Query: 3237 AS---DAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSR 3274
             +   D        +++     G   +++WL +  R  RS+
Sbjct: 245  NNKICDELEETTYEIVIETGNGGETRENVWLILEGRKNRSK 285



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 3/103 (2%)

Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIATPHSL 3176
            KYE++V TG+  G+GT A+V + ++G +  +G R L       F R S D F + T   L
Sbjct: 394  KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LEL 452

Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWL 3219
            G + K+R+ HD+ G    W ++ V V +  T  +  F    WL
Sbjct: 453  GELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 495



 Score = 52.8 bits (125), Expect = 7e-06
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 3124 VKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLGSVWKI 3182
            V TG   G GT +++ + LYG++  +    LD  +A F R   D F I     +    K+
Sbjct: 3    VWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKARFEREQNDTF-IMEILDIAPFTKM 61

Query: 3183 RVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLS 3220
            R+  D  G  P WFL+ ++++++ T     F   DWLS
Sbjct: 62   RIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 99


>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
          Length = 1321

 Score = 74.7 bits (182), Expect = 2e-12
 Identities = 63/217 (29%), Positives = 83/217 (38%), Gaps = 59/217 (27%)

Query: 9   LALALGLGLWLGALAGGPGRGCGPCEPPCL-------CGPAPGAA-CRVNCSGRGLRTLG 60
           L L L L   L  L GG G G       C         G A GAA  +V CS   L  + 
Sbjct: 15  LLLPLSLLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCSSLELAQVL 74

Query: 61  PALRIPADATAL------------------------DVSHNLLRALDVGLLANLSALAEL 96
           P   +P     L                        D+ +NL+ ++D G    LS+L  L
Sbjct: 75  PPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRL 134

Query: 97  DISNNKISTLEEGIFANLFNLSEINLSGNPFE------------------------CDCG 132
           D++NN+I  L   IF  L NL  +NLSGN F                         CDC 
Sbjct: 135 DLTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCN 194

Query: 133 LAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGI 169
           + W+ RW +E+ + V       C  P SL  QP+ G+
Sbjct: 195 ILWMHRWVKEKNITV---RDTRCVYPKSLQAQPVTGV 228


>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
          Length = 545

 Score = 73.6 bits (179), Expect = 4e-12
 Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 1/93 (1%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
           L +  N L AL   L  NLS L  L +S N+++TL EGIF   +NL  + L GNP++CDC
Sbjct: 342 LYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDC 401

Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
            LA+L  W ++   R++  +   CAGP  L GQ
Sbjct: 402 HLAYLFNWLQQYTDRLLNIQ-TYCAGPAYLKGQ 433



 Score = 45.4 bits (106), Expect = 0.001
 Identities = 23/56 (41%), Positives = 34/56 (60%)

Query: 70  TALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
           T L +  N+LR L  GL A+   L  L +++N++ T+ EG FA+L NL  + LS N
Sbjct: 268 TFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYN 323



 Score = 39.3 bits (90), Expect = 0.085
 Identities = 21/54 (38%), Positives = 32/54 (59%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
           L+++ NLL  L   L   L++L  L +SNN +S L +G+F  L +L E+ L  N
Sbjct: 174 LNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSN 227



 Score = 37.0 bits (84), Expect = 0.42
 Identities = 17/57 (29%), Positives = 33/57 (57%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
           L+V+ +    L   + +NL++L +L ++ N +  L EG+F +L  L  ++L GN  +
Sbjct: 102 LEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQ 158


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 73.2 bits (178), Expect = 5e-12
 Identities = 40/107 (37%), Positives = 56/107 (52%), Gaps = 3/107 (2%)

Query: 70  TALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFEC 129
           T L +S+N L+ +       L +L  L +  N ISTL+EGIFA++ +LS + +  NP  C
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYC 870

Query: 130 DCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGC 176
           DC L WL  W    +    +P  A CAGP  + G+ LL  P     C
Sbjct: 871 DCHLRWLSSWV---KTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914



 Score = 62.8 bits (151), Expect = 7e-09
 Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 5/92 (5%)

Query: 96  LDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATC 155
           L + +N+I+T+  G F  L +LS +NL  NPF C+C LAWL  W  ++++    P    C
Sbjct: 642 LSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPR---C 698

Query: 156 AGPGSLAGQPLLGIPLLDSGC--GEEYVACLP 185
             P  L   PL  +   D  C  G+E   CLP
Sbjct: 699 QNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLP 730



 Score = 55.5 bits (132), Expect = 1e-06
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 25/170 (14%)

Query: 62  ALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEIN 121
           A R   D   L +  N +  ++ G    L  L  L ++NN I+T+    F ++  L    
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211

Query: 122 LSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYV 181
           L  N   CDC LAWL +W  ++    +  +   C+GP SL G  +  +   +  C  +  
Sbjct: 212 LHSNHLFCDCHLAWLSQWLRQRPTIGLFTQ---CSGPASLRGLNVAEVQKSEFSCSGQ-- 266

Query: 182 ACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFST-------GQGLAAL 224
                  +G V   + S+         +C A C  +       G+GL A+
Sbjct: 267 -----GEAGRVPTCTLSSG--------SCPAMCTCSNGIVDCRGKGLTAI 303



 Score = 53.1 bits (126), Expect = 6e-06
 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 3/88 (3%)

Query: 77  NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
           N +  +      +L  L+ L + +NKI +L +G F +L  +  ++L+ NPF CDC L WL
Sbjct: 391 NKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWL 450

Query: 137 PRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
              A+  +   ++   A CA P  LA +
Sbjct: 451 ---ADFLRTNPIETSGARCASPRRLANK 475



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 8/97 (8%)

Query: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDV-GLLANLS 91
           C   C C      A  V CS   L  +    RIP     L +++N +  L+  G+   L+
Sbjct: 513 CPHKCRC-----EANVVECSSLKLTKIPE--RIPQSTAELRLNNNEISILEATGMFKKLT 565

Query: 92  ALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
            L ++++SNNK+S +E+G F    ++SE++L+ N  E
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 602



 Score = 42.4 bits (98), Expect = 0.010
 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 7/109 (6%)

Query: 17  LWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSH 76
           LWL   A     G   C   C C         V+C G GL+ +     IP +   L+++ 
Sbjct: 18  LWLLLWAAAWRLGASACPALCTC-----TGTTVDCHGTGLQAIPK--NIPRNTERLELNG 70

Query: 77  NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
           N +  +     A L  L  L +  N+I  +E G F ++  L  + L+ N
Sbjct: 71  NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRN 119


>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
          Length = 560

 Score = 71.6 bits (174), Expect = 2e-11
 Identities = 39/105 (37%), Positives = 55/105 (52%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
           + +  N LRAL   L  NLS+L  + + +N++ TL   +F  L  L+E+ L  N + CDC
Sbjct: 368 VSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDC 427

Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGC 176
           GL     W  +    V   E   CAGPG+ AG PL  +P  D+ C
Sbjct: 428 GLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAEC 472



 Score = 42.4 bits (98), Expect = 0.010
 Identities = 21/54 (38%), Positives = 31/54 (57%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
           L + HN LR +D  +   L  L EL ++ N++  L   +F NL NL  ++LSGN
Sbjct: 127 LFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGN 180



 Score = 40.8 bits (94), Expect = 0.029
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 6/61 (9%)

Query: 77  NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
           N L +LD GLL +L AL EL    N I ++  G F  L NLS + LS N       LA+L
Sbjct: 204 NRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRN------HLAFL 257

Query: 137 P 137
           P
Sbjct: 258 P 258


>gi|41582239 immunoglobulin superfamily containing leucine-rich
           repeat [Homo sapiens]
          Length = 428

 Score = 70.9 bits (172), Expect = 3e-11
 Identities = 57/212 (26%), Positives = 77/212 (36%), Gaps = 75/212 (35%)

Query: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVS----------------- 75
           C  PC CG   G     +C+ R L ++ P    PA+ T L +S                 
Sbjct: 19  CPEPCDCGEKYGFQI-ADCAYRDLESVPPGF--PANVTTLSLSANRLPGLPEGAFREVPL 75

Query: 76  -------HNLLRALDVGLLANLSALAELDISNNKIS------------------------ 104
                  HN +R +  G LA+LS L  LD+S+N IS                        
Sbjct: 76  LQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELT 135

Query: 105 ------------------------TLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWA 140
                                   TL EG F  L  LS + ++ NPF+C CG+ WL  WA
Sbjct: 136 FIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWA 195

Query: 141 EEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
               V + + +   C  P  L G PL  +P L
Sbjct: 196 LTTAVSIPEQDNIACTSPHVLKGTPLSRLPPL 227


>gi|5031809 immunoglobulin superfamily containing leucine-rich
           repeat [Homo sapiens]
          Length = 428

 Score = 70.9 bits (172), Expect = 3e-11
 Identities = 57/212 (26%), Positives = 77/212 (36%), Gaps = 75/212 (35%)

Query: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVS----------------- 75
           C  PC CG   G     +C+ R L ++ P    PA+ T L +S                 
Sbjct: 19  CPEPCDCGEKYGFQI-ADCAYRDLESVPPGF--PANVTTLSLSANRLPGLPEGAFREVPL 75

Query: 76  -------HNLLRALDVGLLANLSALAELDISNNKIS------------------------ 104
                  HN +R +  G LA+LS L  LD+S+N IS                        
Sbjct: 76  LQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELT 135

Query: 105 ------------------------TLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWA 140
                                   TL EG F  L  LS + ++ NPF+C CG+ WL  WA
Sbjct: 136 FIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWA 195

Query: 141 EEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
               V + + +   C  P  L G PL  +P L
Sbjct: 196 LTTAVSIPEQDNIACTSPHVLKGTPLSRLPPL 227


>gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens]
          Length = 347

 Score = 69.3 bits (168), Expect = 8e-11
 Identities = 42/128 (32%), Positives = 72/128 (56%), Gaps = 6/128 (4%)

Query: 48  RVNCSGRGLRTLGPALRIPA-DATALDVSHNLLRALDVGLLANLSALAELDISNNKISTL 106
           R++  G  L+ LG  L +P  D   L ++ N L  +  G    L  L  LD+SNN ++++
Sbjct: 216 RLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASV 275

Query: 107 EEGIFANL----FNLSE-INLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSL 161
            EG++A+L    +++ +  ++SGNP+ CD  L+ L RW + Q+ ++       CAGP ++
Sbjct: 276 PEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAV 335

Query: 162 AGQPLLGI 169
            GQ LL +
Sbjct: 336 KGQTLLAV 343



 Score = 43.5 bits (101), Expect = 0.005
 Identities = 22/57 (38%), Positives = 31/57 (54%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
           LD+S N LR L  GLLAN + L  LD+  N++ TL   +      L  ++L GN  +
Sbjct: 169 LDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQ 225


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 5/134 (3%)

Query: 52  SGRGLRTL-GPALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGI 110
           +G  L T+ G   R  +    L +  NL+  +     A LS++  L + +N+I+T+  G 
Sbjct: 589 TGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGA 648

Query: 111 FANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIP 170
           F  L +LS INL  NPF C+C LAWL +W  ++++    P    C  P  L   P+  + 
Sbjct: 649 FTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPR---CQKPFFLKEIPIQDVA 705

Query: 171 LLDSGC-GEEYVAC 183
           + D  C G E  +C
Sbjct: 706 IQDFTCDGNEESSC 719



 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 3/101 (2%)

Query: 70  TALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFEC 129
           + L +S+N LR + V     L +L  L +  N IS++ EG F +L +LS + L  NP  C
Sbjct: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861

Query: 130 DCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIP 170
           DC L WL  W    +    +P  A C+ P  +A + LL  P
Sbjct: 862 DCSLRWLSEWV---KAGYKEPGIARCSSPEPMADRLLLTTP 899



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 3/88 (3%)

Query: 77  NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
           N +  L V    +L  L  L + +NK+ T+ +G+FA L ++  ++L+ NPF CDC L WL
Sbjct: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448

Query: 137 PRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
              A+  Q   ++   A C+ P  LA +
Sbjct: 449 ---ADYLQDNPIETSGARCSSPRRLANK 473



 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 13/125 (10%)

Query: 4   AAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPAL 63
           A  ARLALAL L      L+G P   C      C C     +A  V+C G GLR +    
Sbjct: 11  AVRARLALALALA---SVLSGPPAVAC---PTKCTC-----SAASVDCHGLGLRAVPRG- 58

Query: 64  RIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLS 123
            IP +A  LD+  N +  +     A L  L  L + +N++S +E G F +L  L  + L+
Sbjct: 59  -IPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLN 117

Query: 124 GNPFE 128
            N  +
Sbjct: 118 KNKLQ 122



 Score = 45.1 bits (105), Expect = 0.002
 Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 9/137 (6%)

Query: 62  ALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEIN 121
           A R   D   L + +N +  ++ G    L  L  L ++NN IS +    F ++  +  + 
Sbjct: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLR 211

Query: 122 LSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYV 181
           L  N   CDC LAWL  W  +   R    +   C  P  L G  +  +        +EYV
Sbjct: 212 LHSNHLYCDCHLAWLSDWLRQ---RRTVGQFTLCMAPVHLRGFNVADVQ------KKEYV 262

Query: 182 ACLPDNSSGTVAAVSFS 198
              P +   +  A S S
Sbjct: 263 CPAPHSEPPSCNANSIS 279



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSA 92
           C  PC C         V+C G+GL  + PA  +P     + +  N ++A+  G       
Sbjct: 280 CPSPCTCSNNI-----VDCRGKGLMEI-PA-NLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332

Query: 93  LAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
           L  +DIS N+IS +    F  L +L+ + L GN
Sbjct: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGN 365



 Score = 40.4 bits (93), Expect = 0.038
 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 8/97 (8%)

Query: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDV-GLLANLS 91
           C   C C         V+CS + L  +   L  P   T L ++ N +  L+  G+   L 
Sbjct: 505 CPEKCRC-----EGTIVDCSNQKLVRIPSHL--PEYVTDLRLNDNEVSVLEATGIFKKLP 557

Query: 92  ALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
            L ++++SNNKI  + EG F    ++ E+ L+GN  E
Sbjct: 558 NLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLE 594


>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
           sapiens]
          Length = 674

 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 6/149 (4%)

Query: 61  PALRIP-ADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSE 119
           P L +P A    L +  N +  +    LA +  L  LD+SNN ++TL  G+F +L NL++
Sbjct: 263 PPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQ 322

Query: 120 INLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEE 179
           + L  NP+ C C L WL  W  + +  VV      C GP  + G  +  I      C E 
Sbjct: 323 LLLRNNPWFCGCNLMWLRDWV-KARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFET 381

Query: 180 YVACLPDNSSGTVAAVSFSAAHEGLLQPE 208
                P       AA + ++ H     P+
Sbjct: 382 G----PQGGVANAAAKTTASNHASATTPQ 406


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 67.8 bits (164), Expect = 2e-10
 Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 72  LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
           L +S+N LR +       L +L  L +  N IS + EG F +L  LS + +  NP  CDC
Sbjct: 806 LILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDC 865

Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIP 170
            + WL  W + +     +P  A CAGPG +A + LL  P
Sbjct: 866 NMQWLSDWVKSE---YKEPGIARCAGPGEMADKLLLTTP 901



 Score = 60.5 bits (145), Expect = 4e-08
 Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 5/98 (5%)

Query: 90  LSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQ 149
           LS++  L + +N+I+T+  G F  L +LS +NL  NPF C+C LAWL  W  ++++    
Sbjct: 629 LSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGN 688

Query: 150 PEAATCAGPGSLAGQPLLGIPLLDSGC--GEEYVACLP 185
           P    C  P  L   P+  + + D  C  G +  +C P
Sbjct: 689 PR---CQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSP 723



 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 77  NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
           N +  L V    +L  L  L + +NK+ T+ +G F+ L  +  ++L+ NPF CDC L WL
Sbjct: 382 NKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWL 441

Query: 137 PRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
              A+      ++   A C  P  LA +
Sbjct: 442 ---ADYLHTNPIETSGARCTSPRRLANK 466



 Score = 49.3 bits (116), Expect = 8e-05
 Identities = 33/102 (32%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 62  ALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEIN 121
           A R   D   L + +N +  ++ G    L  L  L ++NN I+ L    F ++  L    
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205

Query: 122 LSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAG 163
           L  N   CDC LAWL  W   Q+ RV       C GP  L G
Sbjct: 206 LHSNNLYCDCHLAWLSDWL-RQRPRV--GLYTQCMGPSHLRG 244



 Score = 46.6 bits (109), Expect = 5e-04
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 27/195 (13%)

Query: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDV-GLLANLS 91
           C   C C         V+CS + L  +     IP     L +++N    L+  G+   L 
Sbjct: 506 CPEKCRC-----EGTTVDCSNQKLNKIPE--HIPQYTAELRLNNNEFTVLEATGIFKKLP 558

Query: 92  ALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPE 151
            L +++ SNNKI+ +EEG F     ++EI L+ N  E      +  +  E  +  +++  
Sbjct: 559 QLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMF--KGLESLKTLMLRSN 616

Query: 152 AATCAGPGSLAGQPLLGIPLLDSGCGEEYVACLPDNSSGTVAAVSFSAAH-----EGLLQ 206
             TC G  S  G  L  + LL           L DN   TVA  +F   H       L  
Sbjct: 617 RITCVGNDSFIG--LSSVRLLS----------LYDNQITTVAPGAFDTLHSLSTLNLLAN 664

Query: 207 PEACSAFCFSTGQGL 221
           P  C+ +    G+ L
Sbjct: 665 PFNCNCYLAWLGEWL 679



 Score = 45.4 bits (106), Expect = 0.001
 Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 10/115 (8%)

Query: 11  LALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADAT 70
           L+L LGL L  L     + C P +  C       +   V+C G  LR++     IP +  
Sbjct: 9   LSLSLGLVLAILNKVAPQAC-PAQCSC-------SGSTVDCHGLALRSV--PRNIPRNTE 58

Query: 71  ALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
            LD++ N +  +     A L  L  L +  NKIST+E G F +L  L  + L+ N
Sbjct: 59  RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRN 113



 Score = 43.1 bits (100), Expect = 0.006
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 35  PPCLCGPAPGAACR-----VNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLAN 89
           P C     P AAC      V+C G+GL  +     +P   T + +  N ++ +  G  + 
Sbjct: 266 PSCSVLHCP-AACTCSNNIVDCRGKGLTEI--PTNLPETITEIRLEQNTIKVIPPGAFSP 322

Query: 90  LSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
              L  +D+SNN+IS L    F  L +L+ + L GN
Sbjct: 323 YKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGN 358


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 180,592,655
Number of Sequences: 37866
Number of extensions: 9226495
Number of successful extensions: 31271
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 174
Number of HSP's that attempted gapping in prelim test: 29351
Number of HSP's gapped (non-prelim): 1662
length of query: 4302
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4179
effective length of database: 13,590,000
effective search space: 56792610000
effective search space used: 56792610000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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