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Search of human proteins with 205360962
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
(4302 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 8665 0.0
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 8660 0.0
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 326 3e-88
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 179 4e-44
gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] 179 5e-44
gi|31559825 polycystin 1-like 3 [Homo sapiens] 178 9e-44
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 178 1e-43
gi|239745435 PREDICTED: hypothetical protein XP_002343464 [Homo ... 168 9e-41
gi|4505835 polycystin 2 [Homo sapiens] 122 1e-26
gi|19923084 polycystin-1L1 [Homo sapiens] 121 2e-26
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 110 2e-23
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 103 5e-21
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] 84 2e-15
gi|194306623 immunoglobulin superfamily containing leucine-rich ... 81 2e-14
gi|194306621 immunoglobulin superfamily containing leucine-rich ... 81 2e-14
gi|39930401 immunoglobulin superfamily containing leucine-rich r... 81 2e-14
gi|194306618 immunoglobulin superfamily containing leucine-rich ... 81 2e-14
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 78 2e-13
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 75 1e-12
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 75 1e-12
gi|59823631 G protein-coupled receptor 125 [Homo sapiens] 75 2e-12
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 74 4e-12
gi|188528675 slit homolog 1 [Homo sapiens] 73 5e-12
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 72 2e-11
gi|41582239 immunoglobulin superfamily containing leucine-rich r... 71 3e-11
gi|5031809 immunoglobulin superfamily containing leucine-rich re... 71 3e-11
gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens] 69 8e-11
gi|11321571 slit homolog 3 [Homo sapiens] 69 1e-10
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 69 1e-10
gi|4759146 slit homolog 2 [Homo sapiens] 68 2e-10
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 8665 bits (22484), Expect = 0.0
Identities = 4302/4302 (100%), Positives = 4302/4302 (100%)
Query: 1 MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60
MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
Sbjct: 1 MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60
Query: 61 PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120
PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
Sbjct: 61 PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120
Query: 121 NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180
NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
Sbjct: 121 NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180
Query: 181 VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240
VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
Sbjct: 181 VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240
Query: 241 SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300
SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV
Sbjct: 241 SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300
Query: 301 TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360
TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE
Sbjct: 301 TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360
Query: 361 LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420
LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY
Sbjct: 361 LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420
Query: 421 RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480
RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP
Sbjct: 421 RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480
Query: 481 APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540
APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD
Sbjct: 481 APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540
Query: 541 AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600
AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR
Sbjct: 541 AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600
Query: 601 RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660
RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC
Sbjct: 601 RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660
Query: 661 HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720
HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD
Sbjct: 661 HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720
Query: 721 AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780
AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
Sbjct: 721 AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780
Query: 781 LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840
LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT
Sbjct: 781 LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840
Query: 841 NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900
NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP
Sbjct: 841 NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900
Query: 901 WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960
WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG
Sbjct: 901 WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960
Query: 961 SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020
SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ
Sbjct: 961 SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020
Query: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080
GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP
Sbjct: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080
Query: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140
SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA
Sbjct: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140
Query: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200
GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA
Sbjct: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200
Query: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260
AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV
Sbjct: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260
Query: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320
EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN
Sbjct: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320
Query: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380
PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV
Sbjct: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380
Query: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440
GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS
Sbjct: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440
Query: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500
YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW
Sbjct: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500
Query: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560
DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV
Sbjct: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560
Query: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620
PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA
Sbjct: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620
Query: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680
QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG
Sbjct: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680
Query: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740
KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA
Sbjct: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740
Query: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800
ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV
Sbjct: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800
Query: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860
PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG
Sbjct: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860
Query: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920
TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR
Sbjct: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920
Query: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980
LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC
Sbjct: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980
Query: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040
EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV
Sbjct: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040
Query: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100
RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS
Sbjct: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100
Query: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160
PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL
Sbjct: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160
Query: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220
MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR
Sbjct: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220
Query: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280
LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE
Sbjct: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280
Query: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340
SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL
Sbjct: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340
Query: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400
TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS
Sbjct: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400
Query: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460
KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC
Sbjct: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460
Query: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520
ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
Sbjct: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520
Query: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580
HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS
Sbjct: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580
Query: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640
ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA
Sbjct: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640
Query: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700
QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA
Sbjct: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700
Query: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760
ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM
Sbjct: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760
Query: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820
RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS
Sbjct: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820
Query: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880
DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS
Sbjct: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880
Query: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940
DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP
Sbjct: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940
Query: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000
YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR
Sbjct: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000
Query: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060
WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
Sbjct: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060
Query: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120
HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY
Sbjct: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120
Query: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180
EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW
Sbjct: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180
Query: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240
KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA
Sbjct: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240
Query: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300
ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG
Sbjct: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300
Query: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360
AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA
Sbjct: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360
Query: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWP 3420
GQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWP
Sbjct: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWP 3420
Query: 3421 DLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGV 3480
DLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGV
Sbjct: 3421 DLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGV 3480
Query: 3481 SSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGL 3540
SSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGL
Sbjct: 3481 SSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGL 3540
Query: 3541 VEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFL 3600
VEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFL
Sbjct: 3541 VEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFL 3600
Query: 3601 GWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEA 3660
GWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEA
Sbjct: 3601 GWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEA 3660
Query: 3661 RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSE 3720
RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSE
Sbjct: 3661 RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSE 3720
Query: 3721 ELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDY 3780
ELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDY
Sbjct: 3721 ELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDY 3780
Query: 3781 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3840
DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN
Sbjct: 3781 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3840
Query: 3841 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3900
WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL
Sbjct: 3841 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3900
Query: 3901 LTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADR 3960
LTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADR
Sbjct: 3901 LTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADR 3960
Query: 3961 QWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCR 4020
QWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCR
Sbjct: 3961 QWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCR 4020
Query: 4021 ALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWH 4080
ALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWH
Sbjct: 4021 ALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWH 4080
Query: 4081 LSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWM 4140
LSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWM
Sbjct: 4081 LSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWM 4140
Query: 4141 GLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSL 4200
GLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSL
Sbjct: 4141 GLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSL 4200
Query: 4201 GRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG 4260
GRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG
Sbjct: 4201 GRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG 4260
Query: 4261 PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4302
PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST
Sbjct: 4261 PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4302
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 8660 bits (22472), Expect = 0.0
Identities = 4302/4303 (99%), Positives = 4302/4303 (99%), Gaps = 1/4303 (0%)
Query: 1 MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60
MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
Sbjct: 1 MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG 60
Query: 61 PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120
PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
Sbjct: 61 PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI 120
Query: 121 NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180
NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
Sbjct: 121 NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY 180
Query: 181 VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240
VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
Sbjct: 181 VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA 240
Query: 241 SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300
SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV
Sbjct: 241 SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV 300
Query: 301 TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360
TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE
Sbjct: 301 TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE 360
Query: 361 LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420
LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY
Sbjct: 361 LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY 420
Query: 421 RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480
RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP
Sbjct: 421 RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP 480
Query: 481 APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540
APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD
Sbjct: 481 APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD 540
Query: 541 AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600
AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR
Sbjct: 541 AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR 600
Query: 601 RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660
RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC
Sbjct: 601 RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC 660
Query: 661 HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720
HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD
Sbjct: 661 HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD 720
Query: 721 AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780
AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
Sbjct: 721 AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV 780
Query: 781 LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840
LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT
Sbjct: 781 LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT 840
Query: 841 NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900
NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP
Sbjct: 841 NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP 900
Query: 901 WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960
WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG
Sbjct: 901 WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG 960
Query: 961 SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020
SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ
Sbjct: 961 SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ 1020
Query: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080
GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP
Sbjct: 1021 GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP 1080
Query: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140
SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA
Sbjct: 1081 SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA 1140
Query: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200
GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA
Sbjct: 1141 GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA 1200
Query: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260
AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV
Sbjct: 1201 AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV 1260
Query: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320
EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN
Sbjct: 1261 EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN 1320
Query: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380
PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV
Sbjct: 1321 PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV 1380
Query: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440
GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS
Sbjct: 1381 GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS 1440
Query: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500
YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW
Sbjct: 1441 YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW 1500
Query: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560
DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV
Sbjct: 1501 DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV 1560
Query: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620
PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA
Sbjct: 1561 PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA 1620
Query: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680
QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG
Sbjct: 1621 QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG 1680
Query: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740
KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA
Sbjct: 1681 KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA 1740
Query: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800
ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV
Sbjct: 1741 ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV 1800
Query: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860
PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG
Sbjct: 1801 PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG 1860
Query: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920
TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR
Sbjct: 1861 TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR 1920
Query: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980
LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC
Sbjct: 1921 LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC 1980
Query: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040
EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV
Sbjct: 1981 EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV 2040
Query: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100
RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS
Sbjct: 2041 RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS 2100
Query: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160
PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL
Sbjct: 2101 PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL 2160
Query: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220
MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR
Sbjct: 2161 MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR 2220
Query: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280
LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE
Sbjct: 2221 LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE 2280
Query: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340
SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL
Sbjct: 2281 SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL 2340
Query: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400
TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS
Sbjct: 2341 TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS 2400
Query: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460
KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC
Sbjct: 2401 KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC 2460
Query: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520
ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
Sbjct: 2461 ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG 2520
Query: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580
HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS
Sbjct: 2521 HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS 2580
Query: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640
ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA
Sbjct: 2581 ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA 2640
Query: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700
QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA
Sbjct: 2641 QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA 2700
Query: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760
ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM
Sbjct: 2701 ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM 2760
Query: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820
RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS
Sbjct: 2761 RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS 2820
Query: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880
DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS
Sbjct: 2821 DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS 2880
Query: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940
DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP
Sbjct: 2881 DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP 2940
Query: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000
YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR
Sbjct: 2941 YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR 3000
Query: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060
WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
Sbjct: 3001 WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS 3060
Query: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120
HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY
Sbjct: 3061 HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY 3120
Query: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180
EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW
Sbjct: 3121 EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW 3180
Query: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240
KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA
Sbjct: 3181 KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA 3240
Query: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300
ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG
Sbjct: 3241 ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG 3300
Query: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360
AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA
Sbjct: 3301 AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA 3360
Query: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAE-AFVGQMKSDLFLDDSKSLVCWPSGEGTLSW 3419
GQQVLDIDSCLDSSVLDSSFLTFSGLHAE AFVGQMKSDLFLDDSKSLVCWPSGEGTLSW
Sbjct: 3361 GQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSW 3420
Query: 3420 PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG 3479
PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG
Sbjct: 3421 PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG 3480
Query: 3480 VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG 3539
VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG
Sbjct: 3481 VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG 3540
Query: 3540 LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF 3599
LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF
Sbjct: 3541 LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF 3600
Query: 3600 LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE 3659
LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE
Sbjct: 3601 LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE 3660
Query: 3660 ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS 3719
ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS
Sbjct: 3661 ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS 3720
Query: 3720 EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD 3779
EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD
Sbjct: 3721 EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD 3780
Query: 3780 YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH 3839
YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH
Sbjct: 3781 YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH 3840
Query: 3840 NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP 3899
NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP
Sbjct: 3841 NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP 3900
Query: 3900 LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD 3959
LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD
Sbjct: 3901 LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD 3960
Query: 3960 RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC 4019
RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC
Sbjct: 3961 RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC 4020
Query: 4020 RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW 4079
RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW
Sbjct: 4021 RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW 4080
Query: 4080 HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW 4139
HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW
Sbjct: 4081 HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW 4140
Query: 4140 MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS 4199
MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS
Sbjct: 4141 MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS 4200
Query: 4200 LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR 4259
LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR
Sbjct: 4201 LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR 4260
Query: 4260 GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4302
GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST
Sbjct: 4261 GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST 4303
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 326 bits (836), Expect = 3e-88
Identities = 390/1538 (25%), Positives = 647/1538 (42%), Gaps = 199/1538 (12%)
Query: 2602 QADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQ-----IRKNITE-TLVSLRV 2655
+ P+ +++ + A+ ++LN+ +HE Q Q +R+ + E L SL
Sbjct: 889 EGGPEQLLQLAKAVSSMLNQ-----------EHESQGSGQSLSIDVRQKVREHVLGSLSA 937
Query: 2656 HT--VDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIG 2713
T ++D+Q++ LA+ + RE+ CRS + EA + + A TV+ A
Sbjct: 938 VTTGLEDVQRVQE-LAEVL---REVTCRSKELTPSAQWEASLALQHASEALLTVSAKARP 993
Query: 2714 DSILN--ITGDLIHLASSDVRAPQPS--ELGAESPSRMVAS--QAYNLTSALMRILMRSR 2767
+ T DL S + A + E AE+ S +A+ + + + L+ +
Sbjct: 994 EDQRRQAATRDLFQAVGSVLEASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGK 1053
Query: 2768 VLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAP--GPGCHFSIPEAFS-GALANLSDVVQ 2824
+ P LA I R P S P F +P A S +L + V
Sbjct: 1054 LPGGLPAMLATPSISVYTNRIQPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVD 1113
Query: 2825 L-IFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWA 2883
+ I +PFP S++ VS V + + +G IP++ L+ I + +P +S
Sbjct: 1114 IKIMSFPKSPFPAR--SHFDVSGTVGGLRVTSPSGQLIPVKNLSEN--IEILLPRHSQ-- 1167
Query: 2884 ARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLA 2943
S N + P+A + ++ ++ A L +QL++ P+ L
Sbjct: 1168 ---RHSQPTVLN--LTSPEA-----LWVNVTSGEATLGIQLHW----------RPDIALT 1207
Query: 2944 VYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGS-RDPAGSYHLNLSSHFRWS 3002
+ L PN+ + A + P + D P T+ +SP R G Y+L +
Sbjct: 1208 LSLGYGYHPNKSSYDAQTHLVP--MVAPDELP-TWILSPQDLRFGEGVYYLTVVPESDLE 1264
Query: 3003 A-----LQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFV 3057
L V + + S C ++ E W G TSP Q CL HLT FG++ V
Sbjct: 1265 PAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLV 1324
Query: 3058 PPSHVRFVFPEPTADV------NYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAI-- 3109
+ + TA++ N +V+ T V Y+++ + D D ++ +
Sbjct: 1325 MSNAINI---HQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTVL 1381
Query: 3110 ----PFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL-DGDR-AFHRN 3163
PF ++ Y + V TG RG+ T++ V + LYG+D HL D D F R
Sbjct: 1382 EDNDPFA----QYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERG 1437
Query: 3164 SLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVET 3223
++D F ++T LG + +R+WHDN G P+W++ V+V DL R +FL N WLS+
Sbjct: 1438 AVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSI-- 1495
Query: 3224 EANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATC 3283
+++K A++ +F L + GF D HIW SI+ R RS FTR+QR +C
Sbjct: 1496 NVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSC 1555
Query: 3284 CV-LLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILF 3342
C LL+C L + W G D A + ++ + V +GL SS++++P+ L I+
Sbjct: 1556 CFSLLLCTMLTSIMFW-GVPKDPAEQKMDLGKIE-FTWQEVMIGLESSILMFPINLLIVQ 1613
Query: 3343 LFRMSRSKVA----------GSPSPTPAGQQVLD---------------IDSCLDSSVLD 3377
+F+ +R +VA GSP+ TP+ Q + D + S + +
Sbjct: 1614 IFQNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVP 1673
Query: 3378 SSFLTFSGLH---AEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLR 3434
S L + ++ + + ++ ++ ++ V W + P L+ S
Sbjct: 1674 SPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKRED-PVTLTLGSSEMKEKS 1732
Query: 3435 QLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETD 3494
Q + +A GP +D Y + E ++ V G S P H
Sbjct: 1733 QCPKPKAARS-GPWKDSAYRQCLYLQLEHV----EQELRLVGPRGFSQP------HSHAQ 1781
Query: 3495 LLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCA 3554
L L + G L +Q PG W A+ L + +G LP WC
Sbjct: 1782 ALRQLQTLKG----GLGVQ---------PG-TWAPAHASALQVSKPPQG-----LPWWCI 1822
Query: 3555 SLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYF 3614
+ L VA + G + S+ WL+S + SF+ S +PLKVL A +F
Sbjct: 1823 LVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFF 1882
Query: 3615 SLVAKRLHPDEDDTLVESPA--VTPVSARVPRVR---------PPHGFALFLAKEEARKV 3663
+LV KR+ DE+DT+ P + P + R R PP A+ K K
Sbjct: 1883 ALVLKRV-DDEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKE 1941
Query: 3664 KRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELW 3723
++ ++R +L Y+ FL + LL +YG AY L + Q +R F + E +
Sbjct: 1942 QKAFALIREILAYLGFLWMLLLVAYGQRD--PSAYHLNRHL-QHSFTRGFSGVLGFREFF 1998
Query: 3724 PWMAHVLLPYVHGNQ-------SSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFS 3776
W L+ ++G+ +S +G ++RQVR+QE+ P P+ + +S
Sbjct: 1999 KWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSCPLAQQPQAYLNGCRAPYS 2058
Query: 3777 -----TSDYDVGWESPHNGSGTWAYSAPDLLGAWS-WGSCAVYDSGGYVQELGLSLEESR 3830
+DY GW + W Y + D + WG VY GGYV LG + +
Sbjct: 2059 LDAEDMADYGEGWNA--TTLSEWQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQSTS 2116
Query: 3831 DRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALR 3890
LR+L + WLD +RAVF+E T Y+ V L VTL LE A G +++ L
Sbjct: 2117 RILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSALGTFFTHAALQSLRLY 2176
Query: 3891 RLSAGLSLPLLTSVCLL--LFAVHFAVAEARTWHRE------GRWRVLRLGAWARWLLVA 3942
+ G P + + L+ LF +++ V + + +E +W +L L +L +
Sbjct: 2177 PFTDGWH-PFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELAI----ILAS 2231
Query: 3943 LTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAA 4002
+A V+ A L D Q R R SF + A +A + A L+ L VK
Sbjct: 2232 WSALAVFVKRAVLAERDLQRCRNHR---EEGISFSETAAADAALGYIIAFLVLLSTVKLW 2288
Query: 4003 QQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYA 4040
LR + ++ L RA ++ G + ++ + +AY+
Sbjct: 2289 HLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYS 2326
Score = 37.7 bits (86), Expect = 0.25
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 30/199 (15%)
Query: 1087 VEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGV--------- 1137
V NV H + +PGE+ + + + ++T Q V+VR + +++V G+
Sbjct: 304 VSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAGPLC 363
Query: 1138 -LVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAA--------NHTYASRGTYH 1188
V G P+ + L GV YT GD + + +Q + T G
Sbjct: 364 QAVFGDPL-WIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGPGR 422
Query: 1189 VRLEV----NNTVSGAAAQADVRVFEELRGLSVD-MSLAVEQGAPVVVSAAVQTGDNITW 1243
RLE+ N T S + V + E L GL S +E G ++++ ++ G
Sbjct: 423 HRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEEL 482
Query: 1244 TFDMGDGTVLSGPEATVEH 1262
TF+ ++G AT H
Sbjct: 483 TFE------VAGLNATFSH 495
Score = 34.7 bits (78), Expect = 2.1
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 15/126 (11%)
Query: 993 KLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVA 1052
+L + A+ + + T++ N+TV + + GLQ S L L +T + + E+
Sbjct: 424 RLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEELT 483
Query: 1053 FLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFE 1112
F G H+ Q + E F + +V G +L+T+L NAF
Sbjct: 484 F-EVAGLNATFSHE-QVSFGEPFGICRLAV-------------PVEGTFLVTMLVRNAFS 528
Query: 1113 NLTQQV 1118
NL+ ++
Sbjct: 529 NLSLEI 534
>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1731
Score = 179 bits (455), Expect = 4e-44
Identities = 207/850 (24%), Positives = 360/850 (42%), Gaps = 68/850 (8%)
Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
L + +N T L+ + S +P+ L +YL + +PN + + + + D Y
Sbjct: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEE-Y 590
Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
T+ ++P + G+Y++ R Q VSV + C Y+ + W + G
Sbjct: 591 TWMLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
+++ + CL HLT F + FV P R V E T + N + + A
Sbjct: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L
Sbjct: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V
Sbjct: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
IV D+ R FL N WL+V + +++ + S L FR L + + F
Sbjct: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
++WLSI R P ++FTRIQR +CC+ L+ + N V + + + R ++
Sbjct: 886 YLWLSIATRHPWNQFTRIQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
+ V + ++V+++P+ L I LF P Q+ L + + +S L +
Sbjct: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991
Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
+ L A V ++K + FL + + + S D+ ++ S + G
Sbjct: 992 -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050
Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
Q H G E ++ P + F ++Q+ L + + TQ H D L +
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105
Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
S + E L L PS + ++ + + GL K W S+
Sbjct: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159
Query: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619
L + + + +W++S S L + +P+KV+ +SL+
Sbjct: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219
Query: 3620 ---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRLH 3667
RL+ + + T + S+ VP R + +++A E K K+L
Sbjct: 1220 RMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKLF 1278
Query: 3668 GMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMA 3727
+ +LV +LFL + + A Y ++ + + + L AI + S F I ++ +PW
Sbjct: 1279 KLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWAN 1335
Query: 3728 HVLLPYVHGN 3737
H+LLP ++G+
Sbjct: 1336 HILLPSLYGD 1345
Score = 38.1 bits (87), Expect = 0.19
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
RF SF + +++SAA L + L V+ LR + V +TL RA E++G L
Sbjct: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596
Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
+++L YA +A L+ C S + + V G + E + L P+L
Sbjct: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649
>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
Length = 1731
Score = 179 bits (454), Expect = 5e-44
Identities = 206/850 (24%), Positives = 361/850 (42%), Gaps = 68/850 (8%)
Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
L + +N T L+ + S +P+ L +YL + +PN + + + + + D Y
Sbjct: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590
Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
T+ ++P + G+Y++ R Q VSV + C Y+ + W + G
Sbjct: 591 TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
+++ + CL HLT F + FV P R V E T + N + + A
Sbjct: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L
Sbjct: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V
Sbjct: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
IV D+ R FL N WL+V + +++ + S L FR L + + F
Sbjct: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
++WLSI R P ++FTR+QR +CC+ L+ + N V + + + R ++
Sbjct: 886 YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
+ V + ++V+++P+ L I LF P Q+ L + + +S L +
Sbjct: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991
Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
+ L A V ++K + FL + + + S D+ ++ S + G
Sbjct: 992 -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050
Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
Q H G E ++ P + F ++Q+ L + + TQ H D L +
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105
Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
S + E L L PS + ++ + + GL K W S+
Sbjct: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159
Query: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619
L + + + +W++S S L + +P+KV+ +SL+
Sbjct: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219
Query: 3620 ---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRLH 3667
RL+ + + T + S+ VP R + +++A E K K+L
Sbjct: 1220 RMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKLF 1278
Query: 3668 GMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMA 3727
+ +LV +LFL + + A Y ++ + + + L AI + S F I ++ +PW
Sbjct: 1279 KLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWAN 1335
Query: 3728 HVLLPYVHGN 3737
H+LLP ++G+
Sbjct: 1336 HILLPSLYGD 1345
Score = 38.1 bits (87), Expect = 0.19
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
RF SF + +++SAA L + L V+ LR + V +TL RA E++G L
Sbjct: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596
Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
+++L YA +A L+ C S + + V G + E + L P+L
Sbjct: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649
>gi|31559825 polycystin 1-like 3 [Homo sapiens]
Length = 1732
Score = 178 bits (452), Expect = 9e-44
Identities = 206/851 (24%), Positives = 360/851 (42%), Gaps = 69/851 (8%)
Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
L + +N T L+ + S +P+ L +YL + +PN + + + + + D Y
Sbjct: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEE-Y 590
Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
T+ ++P + G+Y++ R Q VSV + C Y+ + W + G
Sbjct: 591 TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
+++ + CL HLT F + FV P R V E T + N + + A
Sbjct: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L
Sbjct: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V
Sbjct: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
IV D+ R FL N WL+V + +++ + S L FR L + + F
Sbjct: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
++WLSI R P ++FTR+QR +CC+ L+ + N V + + + R ++
Sbjct: 886 YLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
+ V + ++V+++P+ L I LF P Q+ L + + +S L +
Sbjct: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991
Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
+ L A V ++K + FL + + + S D+ ++ S + G
Sbjct: 992 -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050
Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
Q H G E ++ P + F ++Q+ L + + TQ H D L +
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105
Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
S + E L L PS + ++ + + GL K W S+
Sbjct: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159
Query: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619
L + + + +W++S S L + +P+KV+ +SL+
Sbjct: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219
Query: 3620 RL----HPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRL 3666
R+ +E T + S+ VP R + +++A E K K+L
Sbjct: 1220 RMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKL 1278
Query: 3667 HGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWM 3726
+ +LV +LFL + + A Y ++ + + + L AI + S F I ++ +PW
Sbjct: 1279 FKLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWA 1335
Query: 3727 AHVLLPYVHGN 3737
H+LLP ++G+
Sbjct: 1336 NHILLPSLYGD 1346
Score = 38.1 bits (87), Expect = 0.19
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
RF SF + +++SAA L + L V+ LR + V +TL RA E++G L
Sbjct: 1538 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1597
Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
+++L YA +A L+ C S + + V G + E + L P+L
Sbjct: 1598 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1650
>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1732
Score = 178 bits (451), Expect = 1e-43
Identities = 210/862 (24%), Positives = 368/862 (42%), Gaps = 91/862 (10%)
Query: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976
L + +N T L+ + S +P+ L +YL + +PN + + + + D Y
Sbjct: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEE-Y 590
Query: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030
T+ ++P + G+Y++ R Q VSV + C Y+ + W + G
Sbjct: 591 TWVLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650
Query: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084
+++ + CL HLT F + FV P R V E T + N + + A
Sbjct: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707
Query: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142
L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L
Sbjct: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767
Query: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200
YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V
Sbjct: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827
Query: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260
IV D+ R FL N WL+V + +++ + S L FR L + + F
Sbjct: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885
Query: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320
++WLSI R P ++FTRIQR +CC+ L+ + N V + + + R ++
Sbjct: 886 YLWLSIATRHPWNQFTRIQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944
Query: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380
+ V + ++V+++P+ L I LF P Q+ L + + +S L +
Sbjct: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991
Query: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439
+ L A V ++K + FL + + + S D+ ++ S + G
Sbjct: 992 -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050
Query: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499
Q H G E ++ P + F ++Q+ L + + TQ H D L +
Sbjct: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105
Query: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559
S LQ+L EL + L EQ + ++ ++ + +++G
Sbjct: 1106 SQ----------LQKLQEL-LETHILPTEQEPSREVTSFAILSSEEGK------KPISNG 1148
Query: 3560 LSLLLVAVAVAVSGWVGAS-----------FPPGVSVAWLLSSSASFLASFLGWEPLKVL 3608
LS L +V + G+ + + +W++S S L + +P+KV+
Sbjct: 1149 LSKWLTSVCWLLLGFTSLASAFFTALYRLELSKDQATSWMISIILSVLQNIFISQPVKVV 1208
Query: 3609 LEALYFSLVAKRL----HPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA-------- 3656
+SL+ R+ +E T + S+ VP R + +++A
Sbjct: 1209 FFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTK 1267
Query: 3657 -KEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLA 3715
E K K+L + +LV +LFL + + A Y ++ + + + L AI + S F
Sbjct: 1268 HPERTLKKKKLFKLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSE 1324
Query: 3716 ITRSEELWPWMAHVLLPYVHGN 3737
I ++ +PW H+LLP ++G+
Sbjct: 1325 IKLLQDFYPWANHILLPSLYGD 1346
Score = 38.1 bits (87), Expect = 0.19
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031
RF SF + +++SAA L + L V+ LR + V +TL RA E++G L
Sbjct: 1538 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1597
Query: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085
+++L YA +A L+ C S + + V G + E + L P+L
Sbjct: 1598 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1650
>gi|239745435 PREDICTED: hypothetical protein XP_002343464 [Homo
sapiens]
Length = 146
Score = 168 bits (426), Expect = 9e-41
Identities = 82/84 (97%), Positives = 83/84 (98%)
Query: 1016 MNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESF 1075
MNRMQGL+VSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESF
Sbjct: 1 MNRMQGLRVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESF 60
Query: 1076 PVPDPSVAQVLVEHNVMHTYAAPG 1099
PVPDPSVAQVLVEHNV HTYAAPG
Sbjct: 61 PVPDPSVAQVLVEHNVTHTYAAPG 84
>gi|4505835 polycystin 2 [Homo sapiens]
Length = 968
Score = 122 bits (305), Expect = 1e-26
Identities = 103/421 (24%), Positives = 178/421 (42%), Gaps = 25/421 (5%)
Query: 3655 LAKEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAY-RLQSAI-----KQEL 3708
+ + + K L +LR L+ Y+LFL+V + +YG S + + Y R+ S + +
Sbjct: 206 MEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKT 265
Query: 3709 HSRAFLAITRSEELWPWMAHVLLPYVH-----GNQSSPE-----------LGPPRLRQVR 3752
F ++ E+ W + LL ++ NQ+ + LG PR+RQ+R
Sbjct: 266 EKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLR 325
Query: 3753 LQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWESPHNGSGTWAY-SAPDLLGAWSWGSCA 3811
++ P R +S S D P NG+ W Y S DL G+ WG A
Sbjct: 326 VRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGT-AWIYTSEKDLNGSSHWGIIA 384
Query: 3812 VYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLE 3871
Y GY +L + EE+ ++ L+ + WLD +RA F++ + Y+ + L V L +E
Sbjct: 385 TYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVE 444
Query: 3872 FPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREGRWRVLR 3931
FPA G + + +P L R L + F + + V E R + R
Sbjct: 445 FPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFR 504
Query: 3932 LGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAA 3991
W +V + + + + ++ + F +F+ +A +AA
Sbjct: 505 -SFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAA 563
Query: 3992 SLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCV 4051
+F + +K + + F R S T+ R +L G + ++ +AYAQLA L+ + V
Sbjct: 564 VTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQV 623
Query: 4052 D 4052
D
Sbjct: 624 D 624
>gi|19923084 polycystin-1L1 [Homo sapiens]
Length = 2849
Score = 121 bits (303), Expect = 2e-26
Identities = 99/367 (26%), Positives = 163/367 (44%), Gaps = 39/367 (10%)
Query: 2993 LNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFG 3052
+N + HF+W C ++ + + W++E P TSP + C L AF
Sbjct: 1680 VNYTVHFQWIR-----------CLFWDKRE--WKSERFSPQPGTSPEKVNCSYHRLAAFA 1726
Query: 3053 -------ASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASR 3105
AS V PE N + + ++ Y + A ++D + +
Sbjct: 1727 LLRRKLKASFEVSDISKLQSHPE-----NLLPSIFIMGSVILYGFLVAKSRQVDHHEKKK 1781
Query: 3106 GRAIPF--CGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA--FH 3161
I G Y +++ TG+ + T+ V I+L G + S + L F
Sbjct: 1782 AGYIFLQEASLPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFE 1841
Query: 3162 RNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSV 3221
RNS F ++ P LG + KIR+WHD++G SP WF+ HV+V++L T + FF WLS
Sbjct: 1842 RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS- 1900
Query: 3222 ETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRA 3281
+ G VE+E+ L FR+L + D H+WLS++ RP SR+ R
Sbjct: 1901 -AGRHDGRVERELTCLQGG--LGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRL 1957
Query: 3282 TCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAIL 3341
T L+C++ A+ V H+ +SP ++ + VGL+ +++ P +
Sbjct: 1958 TVSFSLLCVYACLTAL----VAAGGQEQPHLD-VSP-TLGSFRVGLLCTLLASPGAQLLS 2011
Query: 3342 FLFRMSR 3348
LFR+S+
Sbjct: 2012 LLFRLSK 2018
Score = 85.1 bits (209), Expect = 1e-15
Identities = 97/373 (26%), Positives = 154/373 (41%), Gaps = 26/373 (6%)
Query: 1938 HSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQ 1997
H FP + + VS + V +QA + V + + V AT T+ FTA +
Sbjct: 473 HHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTV-FATDTDITFTAVTK 531
Query: 1998 RGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSE-NRTLVLE 2056
+ + WYF D V + R + + V+A N + S + V+
Sbjct: 532 ETIPLEFEWYFG-----EDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIR 586
Query: 2057 VQDAVQYVALQS-GPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSYL 2115
VQ + L S N S FE + VAY WDFGDG+ + + H Y
Sbjct: 587 VQKKIVANRLTSPSSALVNASVAFECWINFGTD-VAYLWDFGDGTVSLGSSS--SSHVYS 643
Query: 2116 RPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQ--RNYLEAHV 2173
R G++ V+V A N VS + + + C+ P V + P +V + RSQ R +
Sbjct: 644 REGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEA 703
Query: 2174 DLRDCVTYQTEYRWEVYRTASCQRPGRPARVALP-GVDVSRPRLVLPRLALPVGHYCFVF 2232
+ ++ Y W + G P V+LP VD R L+LP L G+Y +
Sbjct: 704 AVFCDISQGLSYTWNL-----MDSEGLP--VSLPAAVDTHRQTLILPSHTLEYGNYTALA 756
Query: 2233 VVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRD--LVLDGSESYDPNLEDGD 2290
V + + + + V + V +I G++ +S T +VL G++S+DP D
Sbjct: 757 KVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRTTSSPIVLRGTQSFDP---DDP 813
Query: 2291 QTPLSFHWACVAS 2303
L +HW C +
Sbjct: 814 GATLRYHWECATA 826
Score = 73.9 bits (180), Expect = 3e-12
Identities = 139/592 (23%), Positives = 213/592 (35%), Gaps = 102/592 (17%)
Query: 3548 LLPAWCASLAHGLSLLLVAVAVAVS-------GWVGASFPPGVSVAWLLSSSASFLASFL 3600
L+P W +L S + A+ S G++ F V WL S S +
Sbjct: 2121 LMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIF 2180
Query: 3601 GWEPLKVLLEALYFSLVAK-----------RLHPDEDDTLVE----------SPAVTPVS 3639
+PL V L AL F+ + D D L E S ++ +
Sbjct: 2181 ITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCSIPDCA 2240
Query: 3640 ARVPRV-------------RPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLA 3686
V +V PP L ++ R+ R LR + + +L LL+ L
Sbjct: 2241 GEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLLLLLCV 2300
Query: 3687 SYGDASCHGHAYRLQSAIKQEL--HSRAFLAITRS-EELWPWMAHVLLP--YVHGNQSSP 3741
YG S Y L AI++E ++R L R+ + W W LL Y G S+
Sbjct: 2301 IYGRFS--QDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLYPGGTPSAR 2358
Query: 3742 E--------------LGPPRLRQVRLQEALYPDPPGP-------RVHTCSAAGGFSTSDY 3780
+G +RQ+++ PP P + TCS G + Y
Sbjct: 2359 VPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEVGGPENPY 2418
Query: 3781 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3840
+ P N + T + P G C + V LG + E+ L L+
Sbjct: 2419 LI---DPENQNVT--LNGP--------GGCGTRED--CVLSLGRTRTEAHTALSRLRASM 2463
Query: 3841 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3900
W+D +RAV + T Y+P L +V+LR+E G + + V F++ R + L L
Sbjct: 2464 WIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL 2523
Query: 3901 LTS--VCLLLFAVHFAVAEARTWHRE--GRWRVLRLGAWARWLLVALTAATALVRLAQLG 3956
+ V L L +H V R + WR R W +V ++ V +
Sbjct: 2524 MLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPR--NWLELSVVGVSLTYYAVSGHLVT 2581
Query: 3957 AADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGK 4016
A +F RG R F +A + AR L LLFL +K +
Sbjct: 2582 LAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS 2641
Query: 4017 TLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGT 4068
+ +LP + L ++ A + L L+ S+W VL PGT
Sbjct: 2642 MMRHSLPSIFVAGLVGALMLAALSHLHRFLL-----SMW-------VLPPGT 2681
Score = 61.6 bits (148), Expect = 2e-08
Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 20/232 (8%)
Query: 1313 LTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFT 1372
++A++ + H F D N + V H+F ++ ++ + ++V + +
Sbjct: 442 VSAFMNSSSVHEDEVLVFADSQVN---QKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWH 498
Query: 1373 SICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVT 1432
S+ V ++ +V++ + A P + W FG E P R +
Sbjct: 499 SMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFG--EDPPVRTTSRSIK 556
Query: 1433 FIYRDPGSYLVTVTASNNISAA-NDSALVEVQEPVLV------TSIKVNGSLGLELQQPY 1485
P Y V V ASN +S+ ++ ++ VQ+ ++ +S VN S+ E
Sbjct: 557 KRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPSSALVNASVAFECW--- 613
Query: 1486 LFSAVGRGRPASYLWDLGDGG-WLEGPEVTHAYNSTGDFTVRVAGWNEVSRS 1536
+ G +YLWD GDG L +H Y+ G+FTV V +N VS S
Sbjct: 614 ----INFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS 661
Score = 46.2 bits (108), Expect = 7e-04
Identities = 73/328 (22%), Positives = 126/328 (38%), Gaps = 46/328 (14%)
Query: 1513 VTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSL 1572
V H + S + V +V S+AW ++TV +++ + V + TV + ++F+
Sbjct: 471 VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530
Query: 1573 EAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGT-------FNIIVTAENEVGSAQDSIF 1625
+ + + W + P + T RS+ + ++V A N + S
Sbjct: 531 KETIPLEFEWYFGE-------DPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPH 583
Query: 1626 VYVLQLIEGLQVVGGGRYFPT----NHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSGK 1681
V +Q ++V P+ N +V + + GT+V+Y W D G G
Sbjct: 584 VIRVQ----KKIVANRLTSPSSALVNASVAFECWINFGTDVAYLW----DFGDGTVSLGS 635
Query: 1682 GFSLTVL-EAGTYHVQLRATNMLGSA---------WADCTMDFVEPVGWLMVAA-SPNPA 1730
S V G + V++ A N + ++ C V+ +G V P
Sbjct: 636 SSSSHVYSREGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPV 695
Query: 1731 AVNTSVTLSAELAGGSGVVYTWSL--EEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLG 1788
+ + + G+ YTW+L EGL TH T L T+ GN
Sbjct: 696 RLGVTFEAAVFCDISQGLSYTWNLMDSEGLPVSLPAAVDTHR-QTLILPSHTLEYGN--Y 752
Query: 1789 SANATVEVDVQVPVS----GLSIRASEP 1812
+A A V+++ V S GL +RA P
Sbjct: 753 TALAKVQIEGSVVYSNYCVGLEVRAQAP 780
Score = 44.7 bits (104), Expect = 0.002
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 21/223 (9%)
Query: 1091 VMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYP-- 1148
V+H + + Y ++ ++ + ++V + SV+V + V +TF
Sbjct: 471 VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530
Query: 1149 -HPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADV- 1206
+P + + W FG+ PV T S+ + Y V ++ +N +S ++ V
Sbjct: 531 KETIP----LEFEWYFGEDPPVRTTSRSIKKRLSIPQW-YRVMVKASNRMSSVVSEPHVI 585
Query: 1207 RVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEHVYLR 1266
RV +++ + + A V + G ++ + +D GDGTV G ++ HVY R
Sbjct: 586 RVQKKIVANRLTSPSSALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSS-SHVYSR 644
Query: 1267 AQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQP 1309
TV V A + A +L +F++ C P QP
Sbjct: 645 EGEFTVEVLAFNNVS--ASTLRQQLFIV---------CEPCQP 676
Score = 38.9 bits (89), Expect = 0.11
Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 992 FKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEV 1051
+++ + ASN +S+V +V R+ + T P+ NA++A + + +V
Sbjct: 565 YRVMVKASNRMSSVVSEPHVI--RVQKKIVANRLTSPSSALVNASVAFECWI--NFGTDV 620
Query: 1052 AFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASN-- 1109
A+LW FGDG +L + H Y+ GE+ + VLA N
Sbjct: 621 AYLWDFGDGTVSLG----------------------SSSSSHVYSREGEFTVEVLAFNNV 658
Query: 1110 AFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRP------VTFYPHPL-PSPGGVLYTWD 1162
+ L QQ+ + P + + G + R VTF G+ YTW+
Sbjct: 659 SASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWN 718
Query: 1163 FGDGSPVLTQSQPAANHTY 1181
D S L S PAA T+
Sbjct: 719 LMD-SEGLPVSLPAAVDTH 736
>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
Length = 805
Score = 110 bits (276), Expect = 2e-23
Identities = 105/416 (25%), Positives = 179/416 (43%), Gaps = 43/416 (10%)
Query: 3670 LRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSR-------AFLAITRSEEL 3722
LR LLVY++FL+ L +YG S + Y + + EL +F AI+ +
Sbjct: 101 LRELLVYIVFLVDICLLTYGMTSSSAYYY---TKVMSELFLHTPSDTGVSFQAISSMADF 157
Query: 3723 WPWMAHVLLPYV------------HGNQS-----SPELGPPRLRQVRLQEALYPDPPGPR 3765
W + LL + HG+ S + LG PRLRQ++++ R
Sbjct: 158 WDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFR 217
Query: 3766 VHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGAWS-WGSCAVYDSGGYVQELGL 3824
S +S + P NG+ W Y + D LG +S WG Y GGY +L
Sbjct: 218 EDILSCYDVYSPDKEEQLPFGPFNGTA-WTYHSQDELGGFSHWGRLTSYSGGGYYLDLPG 276
Query: 3825 SLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSV 3884
S + S + LR LQ WLD +R VF++ + Y+ + L + L +EFPA G A+ + +
Sbjct: 277 SRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQI 336
Query: 3885 RPFALRRLSAGLSLPLL-TSVCLLLFAVHFAVAEA------RTWHREGRWRVLRLGAWAR 3937
R L R + ++ V +F ++ V E R + W +L L
Sbjct: 337 RTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDL----- 391
Query: 3938 WLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLL 3997
+++ L+ + + +R + ++ +P + F+ +A + + A LF
Sbjct: 392 -VVILLSIVAVGFHIFRTLEVNRLMGKLLQ-QPNTYADFEFLAFWQTQYNNMNAVNLFFA 449
Query: 3998 LVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDS 4053
+K + + F + + TL R ++LG + ++ AYAQL LL + V++
Sbjct: 450 WIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVEN 505
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 103 bits (256), Expect = 5e-21
Identities = 128/558 (22%), Positives = 217/558 (38%), Gaps = 77/558 (13%)
Query: 3548 LLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKV 3607
+LP WC +A L +++ + G ++ S+ WL +S SF S L +P K+
Sbjct: 1571 VLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKI 1630
Query: 3608 LLEALY---------------------FSLVAKRLHPDEDDTLVESPAVTPVSARVPRVR 3646
+L + + L R+HP+E + + V R R+
Sbjct: 1631 ILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQI----VRIRGTRMY 1686
Query: 3647 PPHGFALFLAKEEARKVKRLHGMLRSLLVYM---------LFLLVTLLASYGDASCHGHA 3697
P L ++E R KR + R L+++ L LL+ L+ C +
Sbjct: 1687 QP------LTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN 1740
Query: 3698 YRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGN--------QSSPELGPPRLR 3749
++ +L + +T+ E+++ W+ VLLP +H + SS LG P +R
Sbjct: 1741 QFIRDRFSMDLAT-----VTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMR 1795
Query: 3750 QVRLQEALYPDPPGPR-VHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGA---- 3804
QVR + + P + V Y + E N SG W +
Sbjct: 1796 QVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNG 1855
Query: 3805 ------------WSWGSCAVYDSGGYVQELGLSLEESRD----RLRFLQLHNWLDNRSRA 3848
+S+G Y SGGY L E+ R RL+ LQ NWLD ++ A
Sbjct: 1856 FTYKPQGTQWLYYSYGLLHTYGSGGYA--LYFFPEQQRFNSTLRLKELQESNWLDEKTWA 1913
Query: 3849 VFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLL 3908
V LELT ++P + L ++++ E G ++S+ F+L S + V +L+
Sbjct: 1914 VVLELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILI 1973
Query: 3909 FAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRG 3968
F + + V E +E V + + L + ++ L + A RF
Sbjct: 1974 FFLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLA-TGIIRFYLS 2032
Query: 3969 RPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGV 4028
P F F V+Q+ R + LLFL ++K + RF + + + ALP + +
Sbjct: 2033 NPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHM 2092
Query: 4029 TLGLVVLGVAYAQLAILL 4046
+ V Y L+
Sbjct: 2093 AFVVSVYFFVYMAFGYLV 2110
Score = 100 bits (249), Expect = 3e-20
Identities = 74/285 (25%), Positives = 125/285 (43%), Gaps = 21/285 (7%)
Query: 3074 NYIVMLTCAVCLVTYMVMAAILHKLDQLDAS-RGRAI--PFCGQRGRFKYEILVKTGWGR 3130
N + + T ++ Y+ +A D++D RG I P Y + + TG
Sbjct: 1183 NPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRW 1242
Query: 3131 GSGTTAHVGIMLYGVDSRS-----GHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVW 3185
GSGT A+V + L G S S H H +R S++ F + T LG + IRVW
Sbjct: 1243 GSGTRANVFVQLRGTVSTSDVHCLSHPHFT---TLYRGSINTFLLTTKSDLGDIHSIRVW 1299
Query: 3186 HDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRF 3245
H+N+G SP+W+L + V +L + F+ WLSV+T +++ L
Sbjct: 1300 HNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDT-----TLDRTFHVTHPDERLTR 1354
Query: 3246 RRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDS 3305
+ ++ H+W SI+ F R+QR +CC+ ++ L N +++
Sbjct: 1355 KDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQE 1414
Query: 3306 AYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSK 3350
+ + ++ +G+ S ++ PV L I FLF S+ K
Sbjct: 1415 QTESRERKYMR-----SMMIGIESVLITIPVQLLITFLFTCSQRK 1454
Score = 72.0 bits (175), Expect = 1e-11
Identities = 141/625 (22%), Positives = 243/625 (38%), Gaps = 80/625 (12%)
Query: 2100 SPGQDTDEPRAEHSYLR------PGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDV 2153
SP PR + ++ G RV + A N S +++V+ Q+ AC V +
Sbjct: 163 SPRSAAPGPRPQQGFVARTECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRI 222
Query: 2154 VL-----PLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASC-QRPGRPARVALP 2207
P+++ M+ + A V L W+V+ + Q P + LP
Sbjct: 223 NTDQKGAPVRLSMQAEAT--INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLP 280
Query: 2208 GVDVSRPRLVL--PRLALPVGHYCFVFVVSF--GDTPLTQ---SIQANVTVAPERLVPII 2260
+++ L + P +L G Y F F VS G+ + + S V + L ++
Sbjct: 281 QLEIRNSPLFIHIPNNSLQWGVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVM 340
Query: 2261 EGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPR-- 2318
G + + T L+LDGS S DP+ D L F W C + R GG + G +
Sbjct: 341 LGDANITANFTEQLILDGSTSSDPD-ADSPLQGLQFFWYC-TTDPRNYGGDRIILGSKEV 398
Query: 2319 -------------GSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPI 2365
+T+ E L Y F + + K R +++ V + G I
Sbjct: 399 CHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVIRKDSR-TAFSDKRVHVLQGPKAI 457
Query: 2366 VSLECV-SCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLD-ETTTS 2423
+ C+ +C+ + S ++ C NC+S +W+ + S ++ D T
Sbjct: 458 AHITCIENCERNFIVSDRFSLFL----NCTNCASRDFY-KWSILSSSGGEMLFDWMGETV 512
Query: 2424 TGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASI---RLSPNRPPLGGSCRLFP 2480
TG G L ++ R F++++ G S+ N P G C++ P
Sbjct: 513 TGRNGAYLSIKAFAFRHFLEAEFSISLYLACW--SGVTSVFRHSFIINHGPQIGECKINP 570
Query: 2481 LGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSY----- 2535
+ AL TK +C+ + D PL Y +++ E V + +L +
Sbjct: 571 AKGI-ALITKFVVQCSNFRDKH---VPLTYKIIVSDLHSVG-EISSVKENTLGTILYLGP 625
Query: 2536 GAVLPPGFRP----HFEVGLAVVVQ--DQLGAAVVALNRSLAITLPEPNGSATGLTVWLH 2589
+ +PP F P + GL + Q D LGA + A + N S T L L
Sbjct: 626 QSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNSSKTVLNQLLS 685
Query: 2590 GLT--ASVLPGLLRQAD--PQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKN 2645
+S+L L+++ D P + Y +A +VLN + L + R R +RK+
Sbjct: 686 FTVGPSSLLSTLIQKKDFLPAGYLLYIVA--SVLNNMKTELPL-------RDDRVNLRKH 736
Query: 2646 ITETLVSLRVHTVDDIQQIAAALAQ 2670
+ + L V T+ +I Q+ + +
Sbjct: 737 LIDQSFLLPVSTLVEIGQVVMTITK 761
>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
Length = 613
Score = 84.3 bits (207), Expect = 2e-15
Identities = 92/429 (21%), Positives = 170/429 (39%), Gaps = 51/429 (11%)
Query: 3661 RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYR-------LQSAIKQELHSRAF 3713
RK + L+ LL+Y +FL+ + ++G + H + L +++ E + F
Sbjct: 20 RKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTN-F 78
Query: 3714 LAITRSEELWPWMAHVLLPYVH-----GNQSSPEL-------------GPPRLRQVRLQE 3755
+I + W +M LL ++ NQ L G PR+RQ+++
Sbjct: 79 KSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKV-- 136
Query: 3756 ALYPDPPGPRVHTCSAAGGFST------SDYDVGWESPHNG----SGTWAYSAPDLLGAW 3805
R +TC F + Y E N + W YS + W
Sbjct: 137 ---------RNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNTNSPW 187
Query: 3806 SWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAA 3865
WG VY +GGY+ L S E++++ L+L++W+ +R +F++ + Y+ V L
Sbjct: 188 HWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCI 247
Query: 3866 VTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREG 3925
+ L EFPA G L S + ++++ L + C + F + V + +
Sbjct: 248 IRLVAEFPATGGILT--SWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIK 305
Query: 3926 RWRVLRLGAWARW--LLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLS 3983
++ + W LL+ L A+ + +++ F +A
Sbjct: 306 EFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWH 365
Query: 3984 SAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLA 4043
+ A +F +K + + F + S TL R + +++G + ++ AYAQL
Sbjct: 366 IYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLG 425
Query: 4044 ILLVSSCVD 4052
L+ S VD
Sbjct: 426 FLVFGSQVD 434
>gi|194306623 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 81.3 bits (199), Expect = 2e-14
Identities = 41/101 (40%), Positives = 56/101 (55%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
L ++HN L +L L L L L I+NN++ TL G F L LS + L NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187
Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
GL WL WA +V + +P++ CA P +L G P+ +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228
>gi|194306621 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 81.3 bits (199), Expect = 2e-14
Identities = 41/101 (40%), Positives = 56/101 (55%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
L ++HN L +L L L L L I+NN++ TL G F L LS + L NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187
Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
GL WL WA +V + +P++ CA P +L G P+ +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228
>gi|39930401 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 81.3 bits (199), Expect = 2e-14
Identities = 41/101 (40%), Positives = 56/101 (55%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
L ++HN L +L L L L L I+NN++ TL G F L LS + L NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187
Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
GL WL WA +V + +P++ CA P +L G P+ +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228
>gi|194306618 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 81.3 bits (199), Expect = 2e-14
Identities = 41/101 (40%), Positives = 56/101 (55%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
L ++HN L +L L L L L I+NN++ TL G F L LS + L NPF C C
Sbjct: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187
Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
GL WL WA +V + +P++ CA P +L G P+ +P L
Sbjct: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPAL 228
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 78.2 bits (191), Expect = 2e-13
Identities = 41/104 (39%), Positives = 66/104 (63%), Gaps = 4/104 (3%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLG 3177
YE++ TG RG+GT A+V I L+G + S L AF + ++D+FR+ T +++G
Sbjct: 45 YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRT-NNVG 103
Query: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVRDLQTAR-SAFFLVNDWLS 3220
++K+R+ HDN GL+ +W+L HVIV D++ +F N+WLS
Sbjct: 104 LIYKVRIEHDNTGLNASWYLDHVIVTDMKRPHLRYYFNCNNWLS 147
Score = 75.1 bits (183), Expect = 1e-12
Identities = 52/161 (32%), Positives = 79/161 (49%), Gaps = 7/161 (4%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD---RAFHRNSLDIFRIATPHSL 3176
Y + VKT G+GT A+V I+++G + SG L F RN+ D F SL
Sbjct: 1825 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 1884
Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLA 3236
G + K+RVWHDNKG+ P W L +V V+D + F + WLS ++E +G V A
Sbjct: 1885 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS-KSEGDGQTVRDFACA 1943
Query: 3237 AS---DAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSR 3274
+ D +++ G +++WL + R RS+
Sbjct: 1944 NNKICDELEETTYEIVIETGNGGETRENVWLILEGRKNRSK 1984
Score = 73.2 bits (178), Expect = 5e-12
Identities = 41/118 (34%), Positives = 68/118 (57%), Gaps = 4/118 (3%)
Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLG 3177
KYE+ V TG G+GT A V I ++G +G R L+ ++ F + + D F + P LG
Sbjct: 173 KYEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEKDNFEKGAEDRFILDAP-DLG 231
Query: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVL 3235
+ KI V H+NKG S WFL +++ D+ R F +N WL+++ + G +++++L
Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDED--DGKIQRDIL 287
Score = 66.2 bits (160), Expect = 7e-10
Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 6/115 (5%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA----FHRNSLDIFRIATPHS 3175
+ + +KTG + +GT A+V I L+G +G L + F R+S++IF + T
Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETL-D 1235
Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLV 3230
LG +WK+R+ HDN G +P WF+ V V + F WL+ + E +G ++
Sbjct: 1236 LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLA-KNEDDGSII 1289
Score = 62.0 bits (149), Expect = 1e-08
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIATPHSL 3176
KYE++V TG+ G+GT A+V + ++G + +G R L F R S D F + T L
Sbjct: 2093 KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LEL 2151
Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWL 3219
G + K+R+ HD+ G W ++ V V + T + F WL
Sbjct: 2152 GELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 2194
Score = 61.6 bits (148), Expect = 2e-08
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 7/131 (5%)
Query: 3117 RFKYEILVKTGWGRGSGTTAHVGIMLYGVD-SRSGHRHL---DGDRAFHRNSLDIFRIAT 3172
R YE+ V TG +GT A+V + +YG + +G R L D F + D F I
Sbjct: 1021 RNTYEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA 1080
Query: 3173 PHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEK 3232
LG++ KIR+ HDN G WFL + + D+ + +F WL+VE + G + +
Sbjct: 1081 I-DLGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEED--DGQLSR 1137
Query: 3233 EVLAASDAALL 3243
E+L ++ +L
Sbjct: 1138 ELLPVDESYVL 1148
Score = 57.4 bits (137), Expect = 3e-07
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLGS 3178
YE+ V TG G GT +++ + LYG++ + LD +A F R D F I +
Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKARFEREQNDTF-IMEILDIAP 1756
Query: 3179 VWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLS 3220
K+R+ D G P WFL+ ++++++ T F DWLS
Sbjct: 1757 FTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798
Score = 55.5 bits (132), Expect = 1e-06
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 11/161 (6%)
Query: 3116 GRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDR----AFHRNSLDIFRIA 3171
G +Y + V TG G+GT A+V + L+G +G R L R F + + D F I
Sbjct: 551 GMARYHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIE 610
Query: 3172 TPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARS--AFFLVNDWLSVETEANGGL 3229
+ ++ +V ++R+ HD KG W+L V+VR+ S F WL + + +G L
Sbjct: 611 SV-TMRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKDKD-DGQL 668
Query: 3230 VEKEVLAASDAALLRFR---RLLVAELQRGFFDKHIWLSIW 3267
V + + + S A L FR L ++ D +++ ++
Sbjct: 669 VRELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLY 709
Score = 55.1 bits (131), Expect = 2e-06
Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 8/131 (6%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGV--DSRSGHRHLDGDRAFHRNSLDIFRIATPHSLG 3177
Y + V TG RG+GT + + +++YG + SG L+G F R DIF I L
Sbjct: 298 YIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIFLEGG-VFDRGRTDIFHIELAVLLS 356
Query: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAA 3237
+ ++ V H N G++ WF + V++ T F ++WL E +A+ GL+E+++
Sbjct: 357 PLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNWLD-EKKAD-GLIERQLY-- 412
Query: 3238 SDAALLRFRRL 3248
+ LR +RL
Sbjct: 413 -EMVSLRKKRL 422
Score = 53.5 bits (127), Expect = 4e-06
Identities = 30/92 (32%), Positives = 52/92 (56%), Gaps = 7/92 (7%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDG-DRAFHRNSLDIFRIATPHSLGS 3178
YE+ + TG G+GT+A V + +YG ++ L + F R S D F++ +G
Sbjct: 816 YEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSKVFERASKDTFQLEAA-DVGE 874
Query: 3179 VWKIRVWHDNKGLSPAWF-----LQHVIVRDL 3205
V+K+R+ H +G P+WF L+H++VR++
Sbjct: 875 VYKLRLGHTGEGFGPSWFVDTVWLRHLVVREV 906
Score = 51.6 bits (122), Expect = 2e-05
Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL----DGDRAFHRNSLDIFRIATPHS 3175
Y + + TG G+GT A V I +YG +G R+L + F R + D F I
Sbjct: 1462 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEAA-D 1520
Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETE 3224
LG ++KI++ HDN W+++ V + + FL WLS++ E
Sbjct: 1521 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKE 1569
Score = 50.4 bits (119), Expect = 4e-05
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 3118 FKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL---DGDRA--FHRNSLDIFRIAT 3172
F+Y I +KTG G+ T + V I LYG S + + L D + F R +D F + T
Sbjct: 684 FRYHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVLLVSDNNLKDYFERGRVDEFTLET 743
Query: 3173 PHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGL 3229
+ +G++ ++ + HD+ G+ +WFL V +R + + F N WL + +A+G L
Sbjct: 744 LN-IGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGKQYTFPANRWLD-KNQADGRL 798
Score = 50.1 bits (118), Expect = 5e-05
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Query: 3117 RFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLD-GDRAFHRNSLDIFRIATPHS 3175
+F + + V T + +GT + + I +YG R+ L+ ++ F ++ FRI P
Sbjct: 424 KFPWSLWVWTTDLKKAGTNSPIFIQIYGQKGRTDEILLNPNNKWFKPGIIEKFRIELP-D 482
Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEAN 3226
LG +KIRVWHD + W L+ + + + F N WL + N
Sbjct: 483 LGRFYKIRVWHDKRSSGSGWHLERMTLMNTLNKDKYNFNCNRWLDANEDDN 533
Score = 45.4 bits (106), Expect = 0.001
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL------DGDRAFHRNSLDIFRIATP 3173
YEI + T +GT A++ I++YG D+ + + + F R S F +
Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 1367
Query: 3174 HSLGSVWKIRVWHDNKGLSPAWFLQHVIVR----DLQTARSAFFLVNDWLSVETE 3224
+ KIR+ H+N G++P W HV +R D A + F + WL+ +
Sbjct: 1368 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSED 1422
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sapiens]
Length = 1114
Score = 75.1 bits (183), Expect = 1e-12
Identities = 52/161 (32%), Positives = 79/161 (49%), Gaps = 7/161 (4%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD---RAFHRNSLDIFRIATPHSL 3176
Y + VKT G+GT A+V I+++G + SG L F RN+ D F SL
Sbjct: 776 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 835
Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLA 3236
G + K+RVWHDNKG+ P W L +V V+D + F + WLS ++E +G V A
Sbjct: 836 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS-KSEGDGQTVRDFACA 894
Query: 3237 AS---DAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSR 3274
+ D +++ G +++WL + R RS+
Sbjct: 895 NNKICDELEETTYEIVIETGNGGETRENVWLILEGRKNRSK 935
Score = 66.2 bits (160), Expect = 7e-10
Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 6/115 (5%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA----FHRNSLDIFRIATPHS 3175
+ + +KTG + +GT A+V I L+G +G L + F R+S++IF + T
Sbjct: 66 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETL-D 124
Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLV 3230
LG +WK+R+ HDN G +P WF+ V V + F WL+ + E +G ++
Sbjct: 125 LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLA-KNEDDGSII 178
Score = 57.4 bits (137), Expect = 3e-07
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLGS 3178
YE+ V TG G GT +++ + LYG++ + LD +A F R D F I +
Sbjct: 649 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKARFEREQNDTF-IMEILDIAP 707
Query: 3179 VWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLS 3220
K+R+ D G P WFL+ ++++++ T F DWLS
Sbjct: 708 FTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749
Score = 51.6 bits (122), Expect = 2e-05
Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL----DGDRAFHRNSLDIFRIATPHS 3175
Y + + TG G+GT A V I +YG +G R+L + F R + D F I
Sbjct: 351 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEAA-D 409
Query: 3176 LGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETE 3224
LG ++KI++ HDN W+++ V + + FL WLS++ E
Sbjct: 410 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKE 458
Score = 45.4 bits (106), Expect = 0.001
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL------DGDRAFHRNSLDIFRIATP 3173
YEI + T +GT A++ I++YG D+ + + + F R S F +
Sbjct: 197 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 256
Query: 3174 HSLGSVWKIRVWHDNKGLSPAWFLQHVIVR----DLQTARSAFFLVNDWLSVETE 3224
+ KIR+ H+N G++P W HV +R D A + F + WL+ +
Sbjct: 257 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSED 311
Score = 40.0 bits (92), Expect = 0.050
Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIAT 3172
KYE++V TG+ G+GT A+V + ++G + +G R L F R S D F + T
Sbjct: 1044 KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET 1099
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sapiens]
Length = 512
Score = 75.1 bits (183), Expect = 1e-12
Identities = 52/161 (32%), Positives = 79/161 (49%), Gaps = 7/161 (4%)
Query: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD---RAFHRNSLDIFRIATPHSL 3176
Y + VKT G+GT A+V I+++G + SG L F RN+ D F SL
Sbjct: 126 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 185
Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLA 3236
G + K+RVWHDNKG+ P W L +V V+D + F + WLS ++E +G V A
Sbjct: 186 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS-KSEGDGQTVRDFACA 244
Query: 3237 AS---DAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSR 3274
+ D +++ G +++WL + R RS+
Sbjct: 245 NNKICDELEETTYEIVIETGNGGETRENVWLILEGRKNRSK 285
Score = 62.0 bits (149), Expect = 1e-08
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Query: 3119 KYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIATPHSL 3176
KYE++V TG+ G+GT A+V + ++G + +G R L F R S D F + T L
Sbjct: 394 KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LEL 452
Query: 3177 GSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWL 3219
G + K+R+ HD+ G W ++ V V + T + F WL
Sbjct: 453 GELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 495
Score = 52.8 bits (125), Expect = 7e-06
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Query: 3124 VKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA-FHRNSLDIFRIATPHSLGSVWKI 3182
V TG G GT +++ + LYG++ + LD +A F R D F I + K+
Sbjct: 3 VWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKARFEREQNDTF-IMEILDIAPFTKM 61
Query: 3183 RVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLS 3220
R+ D G P WFL+ ++++++ T F DWLS
Sbjct: 62 RIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 99
>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
Length = 1321
Score = 74.7 bits (182), Expect = 2e-12
Identities = 63/217 (29%), Positives = 83/217 (38%), Gaps = 59/217 (27%)
Query: 9 LALALGLGLWLGALAGGPGRGCGPCEPPCL-------CGPAPGAA-CRVNCSGRGLRTLG 60
L L L L L L GG G G C G A GAA +V CS L +
Sbjct: 15 LLLPLSLLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCSSLELAQVL 74
Query: 61 PALRIPADATAL------------------------DVSHNLLRALDVGLLANLSALAEL 96
P +P L D+ +NL+ ++D G LS+L L
Sbjct: 75 PPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRL 134
Query: 97 DISNNKISTLEEGIFANLFNLSEINLSGNPFE------------------------CDCG 132
D++NN+I L IF L NL +NLSGN F CDC
Sbjct: 135 DLTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCN 194
Query: 133 LAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGI 169
+ W+ RW +E+ + V C P SL QP+ G+
Sbjct: 195 ILWMHRWVKEKNITV---RDTRCVYPKSLQAQPVTGV 228
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 73.6 bits (179), Expect = 4e-12
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
L + N L AL L NLS L L +S N+++TL EGIF +NL + L GNP++CDC
Sbjct: 342 LYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDC 401
Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
LA+L W ++ R++ + CAGP L GQ
Sbjct: 402 HLAYLFNWLQQYTDRLLNIQ-TYCAGPAYLKGQ 433
Score = 45.4 bits (106), Expect = 0.001
Identities = 23/56 (41%), Positives = 34/56 (60%)
Query: 70 TALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
T L + N+LR L GL A+ L L +++N++ T+ EG FA+L NL + LS N
Sbjct: 268 TFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYN 323
Score = 39.3 bits (90), Expect = 0.085
Identities = 21/54 (38%), Positives = 32/54 (59%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
L+++ NLL L L L++L L +SNN +S L +G+F L +L E+ L N
Sbjct: 174 LNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSN 227
Score = 37.0 bits (84), Expect = 0.42
Identities = 17/57 (29%), Positives = 33/57 (57%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
L+V+ + L + +NL++L +L ++ N + L EG+F +L L ++L GN +
Sbjct: 102 LEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQ 158
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 73.2 bits (178), Expect = 5e-12
Identities = 40/107 (37%), Positives = 56/107 (52%), Gaps = 3/107 (2%)
Query: 70 TALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFEC 129
T L +S+N L+ + L +L L + N ISTL+EGIFA++ +LS + + NP C
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYC 870
Query: 130 DCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGC 176
DC L WL W + +P A CAGP + G+ LL P C
Sbjct: 871 DCHLRWLSSWV---KTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914
Score = 62.8 bits (151), Expect = 7e-09
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 96 LDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATC 155
L + +N+I+T+ G F L +LS +NL NPF C+C LAWL W ++++ P C
Sbjct: 642 LSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPR---C 698
Query: 156 AGPGSLAGQPLLGIPLLDSGC--GEEYVACLP 185
P L PL + D C G+E CLP
Sbjct: 699 QNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLP 730
Score = 55.5 bits (132), Expect = 1e-06
Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 25/170 (14%)
Query: 62 ALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEIN 121
A R D L + N + ++ G L L L ++NN I+T+ F ++ L
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 122 LSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYV 181
L N CDC LAWL +W ++ + + C+GP SL G + + + C +
Sbjct: 212 LHSNHLFCDCHLAWLSQWLRQRPTIGLFTQ---CSGPASLRGLNVAEVQKSEFSCSGQ-- 266
Query: 182 ACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFST-------GQGLAAL 224
+G V + S+ +C A C + G+GL A+
Sbjct: 267 -----GEAGRVPTCTLSSG--------SCPAMCTCSNGIVDCRGKGLTAI 303
Score = 53.1 bits (126), Expect = 6e-06
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 3/88 (3%)
Query: 77 NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
N + + +L L+ L + +NKI +L +G F +L + ++L+ NPF CDC L WL
Sbjct: 391 NKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWL 450
Query: 137 PRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
A+ + ++ A CA P LA +
Sbjct: 451 ---ADFLRTNPIETSGARCASPRRLANK 475
Score = 47.0 bits (110), Expect = 4e-04
Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 8/97 (8%)
Query: 33 CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDV-GLLANLS 91
C C C A V CS L + RIP L +++N + L+ G+ L+
Sbjct: 513 CPHKCRC-----EANVVECSSLKLTKIPE--RIPQSTAELRLNNNEISILEATGMFKKLT 565
Query: 92 ALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
L ++++SNNK+S +E+G F ++SE++L+ N E
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 602
Score = 42.4 bits (98), Expect = 0.010
Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 7/109 (6%)
Query: 17 LWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSH 76
LWL A G C C C V+C G GL+ + IP + L+++
Sbjct: 18 LWLLLWAAAWRLGASACPALCTC-----TGTTVDCHGTGLQAIPK--NIPRNTERLELNG 70
Query: 77 NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
N + + A L L L + N+I +E G F ++ L + L+ N
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRN 119
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 71.6 bits (174), Expect = 2e-11
Identities = 39/105 (37%), Positives = 55/105 (52%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
+ + N LRAL L NLS+L + + +N++ TL +F L L+E+ L N + CDC
Sbjct: 368 VSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDC 427
Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGC 176
GL W + V E CAGPG+ AG PL +P D+ C
Sbjct: 428 GLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAEC 472
Score = 42.4 bits (98), Expect = 0.010
Identities = 21/54 (38%), Positives = 31/54 (57%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
L + HN LR +D + L L EL ++ N++ L +F NL NL ++LSGN
Sbjct: 127 LFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGN 180
Score = 40.8 bits (94), Expect = 0.029
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 6/61 (9%)
Query: 77 NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
N L +LD GLL +L AL EL N I ++ G F L NLS + LS N LA+L
Sbjct: 204 NRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRN------HLAFL 257
Query: 137 P 137
P
Sbjct: 258 P 258
>gi|41582239 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 70.9 bits (172), Expect = 3e-11
Identities = 57/212 (26%), Positives = 77/212 (36%), Gaps = 75/212 (35%)
Query: 33 CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVS----------------- 75
C PC CG G +C+ R L ++ P PA+ T L +S
Sbjct: 19 CPEPCDCGEKYGFQI-ADCAYRDLESVPPGF--PANVTTLSLSANRLPGLPEGAFREVPL 75
Query: 76 -------HNLLRALDVGLLANLSALAELDISNNKIS------------------------ 104
HN +R + G LA+LS L LD+S+N IS
Sbjct: 76 LQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELT 135
Query: 105 ------------------------TLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWA 140
TL EG F L LS + ++ NPF+C CG+ WL WA
Sbjct: 136 FIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWA 195
Query: 141 EEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
V + + + C P L G PL +P L
Sbjct: 196 LTTAVSIPEQDNIACTSPHVLKGTPLSRLPPL 227
>gi|5031809 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 70.9 bits (172), Expect = 3e-11
Identities = 57/212 (26%), Positives = 77/212 (36%), Gaps = 75/212 (35%)
Query: 33 CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVS----------------- 75
C PC CG G +C+ R L ++ P PA+ T L +S
Sbjct: 19 CPEPCDCGEKYGFQI-ADCAYRDLESVPPGF--PANVTTLSLSANRLPGLPEGAFREVPL 75
Query: 76 -------HNLLRALDVGLLANLSALAELDISNNKIS------------------------ 104
HN +R + G LA+LS L LD+S+N IS
Sbjct: 76 LQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELT 135
Query: 105 ------------------------TLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWA 140
TL EG F L LS + ++ NPF+C CG+ WL WA
Sbjct: 136 FIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWA 195
Query: 141 EEQQVRVVQPEAATCAGPGSLAGQPLLGIPLL 172
V + + + C P L G PL +P L
Sbjct: 196 LTTAVSIPEQDNIACTSPHVLKGTPLSRLPPL 227
>gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens]
Length = 347
Score = 69.3 bits (168), Expect = 8e-11
Identities = 42/128 (32%), Positives = 72/128 (56%), Gaps = 6/128 (4%)
Query: 48 RVNCSGRGLRTLGPALRIPA-DATALDVSHNLLRALDVGLLANLSALAELDISNNKISTL 106
R++ G L+ LG L +P D L ++ N L + G L L LD+SNN ++++
Sbjct: 216 RLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASV 275
Query: 107 EEGIFANL----FNLSE-INLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSL 161
EG++A+L +++ + ++SGNP+ CD L+ L RW + Q+ ++ CAGP ++
Sbjct: 276 PEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAV 335
Query: 162 AGQPLLGI 169
GQ LL +
Sbjct: 336 KGQTLLAV 343
Score = 43.5 bits (101), Expect = 0.005
Identities = 22/57 (38%), Positives = 31/57 (54%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
LD+S N LR L GLLAN + L LD+ N++ TL + L ++L GN +
Sbjct: 169 LDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQ 225
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 68.6 bits (166), Expect = 1e-10
Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
Query: 52 SGRGLRTL-GPALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGI 110
+G L T+ G R + L + NL+ + A LS++ L + +N+I+T+ G
Sbjct: 589 TGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGA 648
Query: 111 FANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIP 170
F L +LS INL NPF C+C LAWL +W ++++ P C P L P+ +
Sbjct: 649 FTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPR---CQKPFFLKEIPIQDVA 705
Query: 171 LLDSGC-GEEYVAC 183
+ D C G E +C
Sbjct: 706 IQDFTCDGNEESSC 719
Score = 65.1 bits (157), Expect = 1e-09
Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 3/101 (2%)
Query: 70 TALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFEC 129
+ L +S+N LR + V L +L L + N IS++ EG F +L +LS + L NP C
Sbjct: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
Query: 130 DCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIP 170
DC L WL W + +P A C+ P +A + LL P
Sbjct: 862 DCSLRWLSEWV---KAGYKEPGIARCSSPEPMADRLLLTTP 899
Score = 57.8 bits (138), Expect = 2e-07
Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Query: 77 NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
N + L V +L L L + +NK+ T+ +G+FA L ++ ++L+ NPF CDC L WL
Sbjct: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
Query: 137 PRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
A+ Q ++ A C+ P LA +
Sbjct: 449 ---ADYLQDNPIETSGARCSSPRRLANK 473
Score = 53.9 bits (128), Expect = 3e-06
Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
Query: 4 AAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPAL 63
A ARLALAL L L+G P C C C +A V+C G GLR +
Sbjct: 11 AVRARLALALALA---SVLSGPPAVAC---PTKCTC-----SAASVDCHGLGLRAVPRG- 58
Query: 64 RIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLS 123
IP +A LD+ N + + A L L L + +N++S +E G F +L L + L+
Sbjct: 59 -IPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLN 117
Query: 124 GNPFE 128
N +
Sbjct: 118 KNKLQ 122
Score = 45.1 bits (105), Expect = 0.002
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 9/137 (6%)
Query: 62 ALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEIN 121
A R D L + +N + ++ G L L L ++NN IS + F ++ + +
Sbjct: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLR 211
Query: 122 LSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYV 181
L N CDC LAWL W + R + C P L G + + +EYV
Sbjct: 212 LHSNHLYCDCHLAWLSDWLRQ---RRTVGQFTLCMAPVHLRGFNVADVQ------KKEYV 262
Query: 182 ACLPDNSSGTVAAVSFS 198
P + + A S S
Sbjct: 263 CPAPHSEPPSCNANSIS 279
Score = 44.7 bits (104), Expect = 0.002
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Query: 33 CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSA 92
C PC C V+C G+GL + PA +P + + N ++A+ G
Sbjct: 280 CPSPCTCSNNI-----VDCRGKGLMEI-PA-NLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
Query: 93 LAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
L +DIS N+IS + F L +L+ + L GN
Sbjct: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGN 365
Score = 40.4 bits (93), Expect = 0.038
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 8/97 (8%)
Query: 33 CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDV-GLLANLS 91
C C C V+CS + L + L P T L ++ N + L+ G+ L
Sbjct: 505 CPEKCRC-----EGTIVDCSNQKLVRIPSHL--PEYVTDLRLNDNEVSVLEATGIFKKLP 557
Query: 92 ALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFE 128
L ++++SNNKI + EG F ++ E+ L+GN E
Sbjct: 558 NLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLE 594
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 68.6 bits (166), Expect = 1e-10
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Query: 61 PALRIP-ADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSE 119
P L +P A L + N + + LA + L LD+SNN ++TL G+F +L NL++
Sbjct: 263 PPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQ 322
Query: 120 INLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEE 179
+ L NP+ C C L WL W + + VV C GP + G + I C E
Sbjct: 323 LLLRNNPWFCGCNLMWLRDWV-KARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFET 381
Query: 180 YVACLPDNSSGTVAAVSFSAAHEGLLQPE 208
P AA + ++ H P+
Sbjct: 382 G----PQGGVANAAAKTTASNHASATTPQ 406
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 67.8 bits (164), Expect = 2e-10
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 72 LDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDC 131
L +S+N LR + L +L L + N IS + EG F +L LS + + NP CDC
Sbjct: 806 LILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDC 865
Query: 132 GLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIP 170
+ WL W + + +P A CAGPG +A + LL P
Sbjct: 866 NMQWLSDWVKSE---YKEPGIARCAGPGEMADKLLLTTP 901
Score = 60.5 bits (145), Expect = 4e-08
Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 90 LSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQ 149
LS++ L + +N+I+T+ G F L +LS +NL NPF C+C LAWL W ++++
Sbjct: 629 LSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGN 688
Query: 150 PEAATCAGPGSLAGQPLLGIPLLDSGC--GEEYVACLP 185
P C P L P+ + + D C G + +C P
Sbjct: 689 PR---CQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSP 723
Score = 51.2 bits (121), Expect = 2e-05
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 77 NLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWL 136
N + L V +L L L + +NK+ T+ +G F+ L + ++L+ NPF CDC L WL
Sbjct: 382 NKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWL 441
Query: 137 PRWAEEQQVRVVQPEAATCAGPGSLAGQ 164
A+ ++ A C P LA +
Sbjct: 442 ---ADYLHTNPIETSGARCTSPRRLANK 466
Score = 49.3 bits (116), Expect = 8e-05
Identities = 33/102 (32%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 62 ALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEIN 121
A R D L + +N + ++ G L L L ++NN I+ L F ++ L
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 122 LSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAG 163
L N CDC LAWL W Q+ RV C GP L G
Sbjct: 206 LHSNNLYCDCHLAWLSDWL-RQRPRV--GLYTQCMGPSHLRG 244
Score = 46.6 bits (109), Expect = 5e-04
Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 27/195 (13%)
Query: 33 CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDV-GLLANLS 91
C C C V+CS + L + IP L +++N L+ G+ L
Sbjct: 506 CPEKCRC-----EGTTVDCSNQKLNKIPE--HIPQYTAELRLNNNEFTVLEATGIFKKLP 558
Query: 92 ALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPE 151
L +++ SNNKI+ +EEG F ++EI L+ N E + + E + +++
Sbjct: 559 QLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMF--KGLESLKTLMLRSN 616
Query: 152 AATCAGPGSLAGQPLLGIPLLDSGCGEEYVACLPDNSSGTVAAVSFSAAH-----EGLLQ 206
TC G S G L + LL L DN TVA +F H L
Sbjct: 617 RITCVGNDSFIG--LSSVRLLS----------LYDNQITTVAPGAFDTLHSLSTLNLLAN 664
Query: 207 PEACSAFCFSTGQGL 221
P C+ + G+ L
Sbjct: 665 PFNCNCYLAWLGEWL 679
Score = 45.4 bits (106), Expect = 0.001
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 10/115 (8%)
Query: 11 LALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADAT 70
L+L LGL L L + C P + C + V+C G LR++ IP +
Sbjct: 9 LSLSLGLVLAILNKVAPQAC-PAQCSC-------SGSTVDCHGLALRSV--PRNIPRNTE 58
Query: 71 ALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
LD++ N + + A L L L + NKIST+E G F +L L + L+ N
Sbjct: 59 RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRN 113
Score = 43.1 bits (100), Expect = 0.006
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 8/96 (8%)
Query: 35 PPCLCGPAPGAACR-----VNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLAN 89
P C P AAC V+C G+GL + +P T + + N ++ + G +
Sbjct: 266 PSCSVLHCP-AACTCSNNIVDCRGKGLTEI--PTNLPETITEIRLEQNTIKVIPPGAFSP 322
Query: 90 LSALAELDISNNKISTLEEGIFANLFNLSEINLSGN 125
L +D+SNN+IS L F L +L+ + L GN
Sbjct: 323 YKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGN 358
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 180,592,655
Number of Sequences: 37866
Number of extensions: 9226495
Number of successful extensions: 31271
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 174
Number of HSP's that attempted gapping in prelim test: 29351
Number of HSP's gapped (non-prelim): 1662
length of query: 4302
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4179
effective length of database: 13,590,000
effective search space: 56792610000
effective search space used: 56792610000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.