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Search of human proteins with 20357588
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
(1872 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 3794 0.0
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 3782 0.0
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 3380 0.0
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 84 1e-15
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 84 1e-15
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 84 1e-15
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 79 5e-14
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 74 1e-12
gi|164419758 bromodomain containing 2 [Homo sapiens] 73 2e-12
gi|4826806 bromodomain containing 2 [Homo sapiens] 73 2e-12
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 70 2e-11
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 68 7e-11
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 68 7e-11
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 68 7e-11
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 67 2e-10
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 66 3e-10
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 65 8e-10
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 65 8e-10
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 63 3e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 63 3e-09
gi|34996489 pleckstrin homology domain interacting protein [Homo... 63 3e-09
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 62 4e-09
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 62 7e-09
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 62 7e-09
gi|38788260 bromodomain PHD finger transcription factor isoform ... 61 1e-08
gi|38788274 bromodomain PHD finger transcription factor isoform ... 61 1e-08
gi|119943102 CREB binding protein isoform b [Homo sapiens] 60 2e-08
gi|119943104 CREB binding protein isoform a [Homo sapiens] 60 2e-08
gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 60 3e-08
gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 60 3e-08
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 3794 bits (9840), Expect = 0.0
Identities = 1872/1872 (100%), Positives = 1872/1872 (100%)
Query: 1 MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD 60
MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD
Sbjct: 1 MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD 60
Query: 61 ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE 120
ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE
Sbjct: 61 ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE 120
Query: 121 SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGEKV 180
SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGEKV
Sbjct: 121 SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGEKV 180
Query: 181 DFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLR 240
DFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLR
Sbjct: 181 DFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLR 240
Query: 241 FLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPPP 300
FLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPPP
Sbjct: 241 FLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPPP 300
Query: 301 PPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDGS 360
PPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDGS
Sbjct: 301 PPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDGS 360
Query: 361 GFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLADENFLMVTQLHWEDDIIWDGED 420
GFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLADENFLMVTQLHWEDDIIWDGED
Sbjct: 361 GFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLADENFLMVTQLHWEDDIIWDGED 420
Query: 421 VKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLDDDKPWYSIFPIDNEDLVYGRW 480
VKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLDDDKPWYSIFPIDNEDLVYGRW
Sbjct: 421 VKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLDDDKPWYSIFPIDNEDLVYGRW 480
Query: 481 EDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSRI 540
EDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSRI
Sbjct: 481 EDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSRI 540
Query: 541 LLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQ 600
LLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQ
Sbjct: 541 LLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQ 600
Query: 601 PFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGG 660
PFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGG
Sbjct: 601 PFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGG 660
Query: 661 EMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYG 720
EMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYG
Sbjct: 661 EMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYG 720
Query: 721 ETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIF 780
ETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIF
Sbjct: 721 ETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIF 780
Query: 781 VVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSES 840
VVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSES
Sbjct: 781 VVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSES 840
Query: 841 SIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKD 900
SIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKD
Sbjct: 841 SIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKD 900
Query: 901 AGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCG 960
AGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCG
Sbjct: 901 AGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCG 960
Query: 961 EGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKL 1020
EGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKL
Sbjct: 961 EGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKL 1020
Query: 1021 SRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSST 1080
SRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSST
Sbjct: 1021 SRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSST 1080
Query: 1081 EVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAA 1140
EVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAA
Sbjct: 1081 EVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAA 1140
Query: 1141 SGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTT 1200
SGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTT
Sbjct: 1141 SGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTT 1200
Query: 1201 KDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDL 1260
KDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDL
Sbjct: 1201 KDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDL 1260
Query: 1261 KLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEG 1320
KLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEG
Sbjct: 1261 KLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEG 1320
Query: 1321 TKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTD 1380
TKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTD
Sbjct: 1321 TKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTD 1380
Query: 1381 PMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYP 1440
PMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYP
Sbjct: 1381 PMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYP 1440
Query: 1441 SREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLD 1500
SREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLD
Sbjct: 1441 SREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLD 1500
Query: 1501 DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKH 1560
DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKH
Sbjct: 1501 DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKH 1560
Query: 1561 KYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICT 1620
KYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICT
Sbjct: 1561 KYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICT 1620
Query: 1621 AKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSAT 1680
AKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSAT
Sbjct: 1621 AKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSAT 1680
Query: 1681 PEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSA 1740
PEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSA
Sbjct: 1681 PEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSA 1740
Query: 1741 IQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISY 1800
IQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISY
Sbjct: 1741 IQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISY 1800
Query: 1801 GSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSEDFH 1860
GSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSEDFH
Sbjct: 1801 GSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSEDFH 1860
Query: 1861 SIAGDSDLDSDE 1872
SIAGDSDLDSDE
Sbjct: 1861 SIAGDSDLDSDE 1872
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 3782 bits (9808), Expect = 0.0
Identities = 1872/1893 (98%), Positives = 1872/1893 (98%), Gaps = 21/1893 (1%)
Query: 1 MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD 60
MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD
Sbjct: 1 MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD 60
Query: 61 ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE 120
ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE
Sbjct: 61 ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE 120
Query: 121 SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITG--- 177
SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITG
Sbjct: 121 SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGVSE 180
Query: 178 ------------------EKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 219
EKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA
Sbjct: 181 NGEGIILPSIIAPSSLASEKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 240
Query: 220 TKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVE 279
TKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVE
Sbjct: 241 TKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVE 300
Query: 280 CSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVA 339
CSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVA
Sbjct: 301 CSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVA 360
Query: 340 EWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLAD 399
EWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLAD
Sbjct: 361 EWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLAD 420
Query: 400 ENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLD 459
ENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLD
Sbjct: 421 ENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLD 480
Query: 460 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEE 519
DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEE
Sbjct: 481 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEE 540
Query: 520 ATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQG 579
ATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQG
Sbjct: 541 ATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQG 600
Query: 580 LRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPL 639
LRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPL
Sbjct: 601 LRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPL 660
Query: 640 LKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 699
LKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK
Sbjct: 661 LKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 720
Query: 700 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPE 759
IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPE
Sbjct: 721 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPE 780
Query: 760 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSK 819
TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSK
Sbjct: 781 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSK 840
Query: 820 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAM 879
DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAM
Sbjct: 841 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAM 900
Query: 880 VSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFI 939
VSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFI
Sbjct: 901 VSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFI 960
Query: 940 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLS 999
AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLS
Sbjct: 961 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLS 1020
Query: 1000 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQ 1059
LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQ
Sbjct: 1021 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQ 1080
Query: 1060 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSR 1119
ERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSR
Sbjct: 1081 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSR 1140
Query: 1120 EREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEY 1179
EREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEY
Sbjct: 1141 EREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEY 1200
Query: 1180 VRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQE 1239
VRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQE
Sbjct: 1201 VRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQE 1260
Query: 1240 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQ 1299
KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQ
Sbjct: 1261 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQ 1320
Query: 1300 EEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVG 1359
EEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVG
Sbjct: 1321 EEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVG 1380
Query: 1360 TTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYK 1419
TTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYK
Sbjct: 1381 TTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYK 1440
Query: 1420 IITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1479
IITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE
Sbjct: 1441 IITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1500
Query: 1480 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1539
KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD
Sbjct: 1501 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1560
Query: 1540 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV
Sbjct: 1561 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1620
Query: 1600 CYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMS 1659
CYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMS
Sbjct: 1621 CYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMS 1680
Query: 1660 RDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMS 1719
RDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMS
Sbjct: 1681 RDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMS 1740
Query: 1720 EGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESM 1779
EGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESM
Sbjct: 1741 EGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESM 1800
Query: 1780 MSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRS 1839
MSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRS
Sbjct: 1801 MSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRS 1860
Query: 1840 GPSVLSQVHLSEDEEDSEDFHSIAGDSDLDSDE 1872
GPSVLSQVHLSEDEEDSEDFHSIAGDSDLDSDE
Sbjct: 1861 GPSVLSQVHLSEDEEDSEDFHSIAGDSDLDSDE 1893
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 3380 bits (8765), Expect = 0.0
Identities = 1678/1816 (92%), Positives = 1719/1816 (94%), Gaps = 52/1816 (2%)
Query: 1 MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD 60
M PGCDLLLR AAT+TAA IMSD+DS+EDS+GGGPF+LAG LFGNI+GAGQLEGESVLDD
Sbjct: 1 MRPGCDLLLRAAATVTAA-IMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLEGESVLDD 59
Query: 61 ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE 120
ECKKHLAGLGALGLGSLITELTANEELTGT GALVNDEGW+RSTEDAVDYSDINEVAEDE
Sbjct: 60 ECKKHLAGLGALGLGSLITELTANEELTGTGGALVNDEGWIRSTEDAVDYSDINEVAEDE 119
Query: 121 SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSIT---- 176
S+R+QQTMGSLQPL HSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQD+IT
Sbjct: 120 SQRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDAITCVSE 179
Query: 177 -----------------GEKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 219
EKVDFSS SDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA
Sbjct: 180 SGEDIILPSIIAPSFLASEKVDFSSYSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 239
Query: 220 TKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVE 279
TKLLPSVTELFPEFRPGKVLRFL LFGPGKNVPSVWRSARRKRKK HRELIQEEQIQEVE
Sbjct: 240 TKLLPSVTELFPEFRPGKVLRFLHLFGPGKNVPSVWRSARRKRKK-HRELIQEEQIQEVE 298
Query: 280 CSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVA 339
CSVESEVSQKSLWNYDYAPPPPPEQCL+DDEITMM PVESKFSQSTGD+DKVTDTKPRVA
Sbjct: 299 CSVESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTGDVDKVTDTKPRVA 358
Query: 340 EWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLAD 399
EWRYGPARLWYDMLGV EDGSGFDYGFKLRKT+HEPVIKSRM+EEFRKLEE+NGTDLLAD
Sbjct: 359 EWRYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEESNGTDLLAD 418
Query: 400 ENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLD 459
ENFLMVTQLHWED IIWDGED+KHKGTKPQ ASLAGWLPS TRN MAYNVQQGFA TLD
Sbjct: 419 ENFLMVTQLHWEDSIIWDGEDIKHKGTKPQGASLAGWLPSIKTRNVMAYNVQQGFAPTLD 478
Query: 460 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEE 519
DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVL LDPNDENLILEIPDEKEE
Sbjct: 479 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEE 538
Query: 520 ATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQG 579
ATSNSPSKESKKESSLKKSRILLGKTGVI+EEPQQNMSQPEVKDPWNLSNDEYY+PKQQG
Sbjct: 539 ATSNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPEVKDPWNLSNDEYYFPKQQG 598
Query: 580 LRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPL 639
LRGTFGGNIIQHSIPA+EL QPFFPTHMGPIK+RQFHRPPLKKYSFGALSQPGPHSVQPL
Sbjct: 599 LRGTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPL 658
Query: 640 LKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 699
LKHIKKKAKMREQERQASGGGE+FFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK
Sbjct: 659 LKHIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 718
Query: 700 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPE 759
IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQA ENNLFRAP+YLHKMPE
Sbjct: 719 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPE 778
Query: 760 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSK 819
TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNS+RAN HIRDFLQVFIYRLFWKSK
Sbjct: 779 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSK 838
Query: 820 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAM 879
DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRA
Sbjct: 839 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAK 898
Query: 880 VSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFI 939
VSPEQCCAYYSMIAA+QRLKDAGYGEKSFFAPEEENEEDFQMKIDDEV APWNTTRAFI
Sbjct: 899 VSPEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFI 958
Query: 940 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLS 999
AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQ VKKTVTGTDADLRRLS
Sbjct: 959 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLS 1018
Query: 1000 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQ 1059
LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQA SGEGPMSKFARGSRFSVAEHQ
Sbjct: 1019 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQ 1078
Query: 1060 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSR 1119
ERYKEECQRIFDLQNKVLSSTEVLSTDTDS SAEDSDFEEMGKNIENMLQNKKTSSQLSR
Sbjct: 1079 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSISAEDSDFEEMGKNIENMLQNKKTSSQLSR 1138
Query: 1120 EREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEY 1179
E EEQERKEL+RMLL AGSAASGNNHRDD TAS+TSL SSATG CLKIYRTFRDEEGKEY
Sbjct: 1139 EWEEQERKELRRMLLVAGSAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEY 1198
Query: 1180 VRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQE 1239
VRCETVRKPAVIDAYVRIRTTKDE+FI+KFALFDE+HREEMRKERRRIQEQLRRLKRNQE
Sbjct: 1199 VRCETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQE 1258
Query: 1240 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQ 1299
KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTN PPS PVAMTEEQ
Sbjct: 1259 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQ 1318
Query: 1300 EEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVG 1359
EEELEKTVIHNDNEELIKVEGTKIV GKQLIE+ EVRRKSLVLKFPKQQLPPKKKRRVG
Sbjct: 1319 EEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPPKKKRRVG 1378
Query: 1360 TTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYK 1419
TTVHCDYLN PHKSIHRRRTDPMVTLSSILESIINDMRDLPNT+PFHTPVNAKVVKDYYK
Sbjct: 1379 TTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYK 1438
Query: 1420 IITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1479
IITRPMDLQTLRENVRK LYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE
Sbjct: 1439 IITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1498
Query: 1480 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1539
KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD
Sbjct: 1499 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1558
Query: 1540 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
YYK+IVNP+DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVN+
Sbjct: 1559 YYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNI 1618
Query: 1600 CYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMS 1659
CYQT+TEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYT QPPD+YDTNTSLS S
Sbjct: 1619 CYQTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSLSTS 1678
Query: 1660 RDASVFQDESNMSVLDIPSATPEKQVTQ--------------EG---------------E 1690
RDASVFQDESN+SVLDI +ATPEKQ+ Q EG E
Sbjct: 1679 RDASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPE 1738
Query: 1691 DGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS 1750
GDGDLADEEEGTVQQP+ASVLYEDLL+SEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS
Sbjct: 1739 GGDGDLADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS 1798
Query: 1751 DVGSGGIRPKQPRMLQ 1766
DVG GGIRPKQP MLQ
Sbjct: 1799 DVGYGGIRPKQPFMLQ 1814
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 84.0 bits (206), Expect = 1e-15
Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 514 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 573
Query: 1465 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1524
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 574 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 618
Query: 1525 SWPFHHPVNKKF------------------------------VPDYYKVIVNPMDLETIR 1554
+ P+ +K +PDYY I PMD+E IR
Sbjct: 619 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 678
Query: 1555 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQT 1603
++ +KYQ +S ++D ++ N+ YN PES K A + V +T
Sbjct: 679 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 727
Score = 77.0 bits (188), Expect = 2e-13
Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 34/234 (14%)
Query: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRL 1438
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ +
Sbjct: 351 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 409
Query: 1439 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1498
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 410 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 460
Query: 1499 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1534
++D D + S D NI Q+M + P S F +K
Sbjct: 461 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 520
Query: 1535 KFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588
K PDYYK+I+ PMDL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 521 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 574
Score = 70.9 bits (172), Expect = 1e-11
Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 1367 LNRPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTYP------FHTPVNAKVVKDYY 1418
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
Query: 1419 KIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1478
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
Query: 1479 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1527
E ED + + + IL+ ++ ++A S
Sbjct: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
Query: 1528 --FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1585
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
Query: 1586 ESQYTKTAQEIVNVCYQTLTEYDEH 1610
SQ K A I + Y E + H
Sbjct: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/73 (34%), Positives = 41/73 (56%)
Query: 1527 PFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1586
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 375 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 434
Query: 1587 SQYTKTAQEIVNV 1599
S K ++ V
Sbjct: 435 SAIYKRVLKLQQV 447
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 84.0 bits (206), Expect = 1e-15
Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 546 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 605
Query: 1465 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1524
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 606 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 650
Query: 1525 SWPFHHPVNKKF------------------------------VPDYYKVIVNPMDLETIR 1554
+ P+ +K +PDYY I PMD+E IR
Sbjct: 651 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 710
Query: 1555 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQT 1603
++ +KYQ +S ++D ++ N+ YN PES K A + V +T
Sbjct: 711 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 759
Score = 77.0 bits (188), Expect = 2e-13
Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 34/234 (14%)
Query: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRL 1438
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ +
Sbjct: 383 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 441
Query: 1439 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1498
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 442 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 492
Query: 1499 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1534
++D D + S D NI Q+M + P S F +K
Sbjct: 493 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 552
Query: 1535 KFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588
K PDYYK+I+ PMDL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 553 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 606
Score = 70.9 bits (172), Expect = 1e-11
Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 1367 LNRPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTYP------FHTPVNAKVVKDYY 1418
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
Query: 1419 KIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1478
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
Query: 1479 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1527
E ED + + + IL+ ++ ++A S
Sbjct: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
Query: 1528 --FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1585
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
Query: 1586 ESQYTKTAQEIVNVCYQTLTEYDEH 1610
SQ K A I + Y E + H
Sbjct: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/73 (34%), Positives = 41/73 (56%)
Query: 1527 PFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1586
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 407 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 466
Query: 1587 SQYTKTAQEIVNV 1599
S K ++ V
Sbjct: 467 SAIYKRVLKLQQV 479
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 84.0 bits (206), Expect = 1e-15
Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 546 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 605
Query: 1465 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1524
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 606 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 650
Query: 1525 SWPFHHPVNKKF------------------------------VPDYYKVIVNPMDLETIR 1554
+ P+ +K +PDYY I PMD+E IR
Sbjct: 651 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 710
Query: 1555 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQT 1603
++ +KYQ +S ++D ++ N+ YN PES K A + V +T
Sbjct: 711 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 759
Score = 77.0 bits (188), Expect = 2e-13
Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 34/234 (14%)
Query: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRL 1438
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ +
Sbjct: 383 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 441
Query: 1439 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1498
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 442 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 492
Query: 1499 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1534
++D D + S D NI Q+M + P S F +K
Sbjct: 493 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 552
Query: 1535 KFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588
K PDYYK+I+ PMDL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 553 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 606
Score = 70.9 bits (172), Expect = 1e-11
Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 1367 LNRPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTYP------FHTPVNAKVVKDYY 1418
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
Query: 1419 KIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1478
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
Query: 1479 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1527
E ED + + + IL+ ++ ++A S
Sbjct: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
Query: 1528 --FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1585
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
Query: 1586 ESQYTKTAQEIVNVCYQTLTEYDEH 1610
SQ K A I + Y E + H
Sbjct: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/73 (34%), Positives = 41/73 (56%)
Query: 1527 PFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1586
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 407 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 466
Query: 1587 SQYTKTAQEIVNV 1599
S K ++ V
Sbjct: 467 SAIYKRVLKLQQV 479
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 78.6 bits (192), Expect = 5e-14
Identities = 39/119 (32%), Positives = 67/119 (56%), Gaps = 6/119 (5%)
Query: 1490 RLEKAINPLLD-DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPM 1548
R EK L + DDD A +LD + K DSWPF PV++ + P+YY++I PM
Sbjct: 425 REEKKTKDLFELDDDFTAMYKVLDVVKAHK-----DSWPFLEPVDESYAPNYYQIIKAPM 479
Query: 1549 DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEY 1607
D+ ++ K ++ Y ++E F++D+ + N KYNG S+YTK + + ++ + ++
Sbjct: 480 DISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKH 538
Score = 55.5 bits (132), Expect = 5e-07
Identities = 46/189 (24%), Positives = 91/189 (48%), Gaps = 11/189 (5%)
Query: 1293 VAMTEEQEEELEKTVIHNDNEELIK-VEGTKIVL----GKQLIESADEVRRKSLVLKFPK 1347
+A+ ++++E++ K + EE +K VEG V G L S R K L+ +
Sbjct: 342 LAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREER 401
Query: 1348 QQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLS---SILESIINDMRDLPNTYP 1404
L + K H D N P + ++T + L + + +++ ++ +++P
Sbjct: 402 AWLLAQGKELPPELSHLDP-NSPMRE--EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWP 458
Query: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464
F PV+ +YY+II PMD+ ++ + + LY ++EEF ++ + +N YNG
Sbjct: 459 FLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESS 518
Query: 1465 SLTQISQSM 1473
T++S ++
Sbjct: 519 EYTKMSDNL 527
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 73.9 bits (180), Expect = 1e-12
Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
Query: 1499 LDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNIS 1558
L D DQ+ + L N++ Q + + P +WPF PV K PDYY+VI P+DL+T+ + +
Sbjct: 727 LKDPDQLYTT--LKNLLAQ-IKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLR 783
Query: 1559 KHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTE 1606
Y +R+ F+ D+ ++AN +YN P+S+Y + A + Y L E
Sbjct: 784 SRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
Score = 61.6 bits (148), Expect = 7e-09
Identities = 30/99 (30%), Positives = 54/99 (54%)
Query: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
L + L++++ ++ P+ +PF PV DYY++I P+DL+T+ E +R R Y +R+
Sbjct: 733 LYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKL 792
Query: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1483
F L+ ++ N YN P + + ++ KLKE
Sbjct: 793 FVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 73.2 bits (178), Expect = 2e-12
Identities = 86/372 (23%), Positives = 150/372 (40%), Gaps = 77/372 (20%)
Query: 1510 ILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKVIVNPMDLETIRKNISKHKYQSRES 1567
IL ++++K A +WPF+ PV+ + DY+ +I +PMDL T+++ + Y+ +
Sbjct: 356 ILKELLSKKHAAY--AWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQE 413
Query: 1568 FLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALE 1627
F DV L+ +N KYN P+ A+++ +D+ + A +
Sbjct: 414 FAADVRLMFSNCYKYNPPDHDVVAMARKL-------------------QDVFEFRYAKMP 454
Query: 1628 EAELESLDPMTPGPY---TPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQ 1684
+ +P+ PGP T PP L +++ S +S E E++
Sbjct: 455 D------EPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEE-----------EEE 497
Query: 1685 VTQEGEDGDGDLADEEEGTVQ-----QPQASVLYEDL-LMSEG--EDDEEDAGSDEEGDN 1736
++ E+ + + +D EE Q Q ++E L +S+G + E+
Sbjct: 498 DEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKK 557
Query: 1737 PFSAIQLSESGSD-SDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLED 1795
+ +G+D D G RP QP+ +S + GG A+ G
Sbjct: 558 RKAEKHRGRAGADEDDKGPRAPRPPQPK-------------KSKKASGSGGGSAALGPSG 604
Query: 1796 SNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDE----EEEEQRS-------GPSVL 1844
S GS + PK T+ + GY+ EEEE +E+ Q S G +
Sbjct: 605 FGPSGGSGTKL-PKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLG 663
Query: 1845 SQVHLSEDEEDS 1856
VH+ + E S
Sbjct: 664 RVVHIIQAREPS 675
Score = 58.5 bits (140), Expect = 6e-08
Identities = 48/215 (22%), Positives = 95/215 (44%), Gaps = 25/215 (11%)
Query: 1280 PLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEV--- 1336
PL T APP+ P+A + + + + T I G+ L A +
Sbjct: 260 PLLAVTAAPPAQPLAKKKGVKRKADTTT---PTPTAILAPGSPASPPGSLEPKAARLPPM 316
Query: 1337 -RRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRR-TDPMVTLSSILESIIN 1394
R +K P++ LP +++ H+S + + ++ + + IL+ +++
Sbjct: 317 RRESGRPIKPPRKDLPDSQQQ--------------HQSSKKGKLSEQLKHCNGILKELLS 362
Query: 1395 DMRDLPNTYPFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELI 1452
+ +PF+ PV+A + DY+ II PMDL T++ + R Y +EF + L+
Sbjct: 363 K-KHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLM 421
Query: 1453 VKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDK 1487
N YN P H + +++ + D+ + + + D+
Sbjct: 422 FSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDE 456
Score = 57.0 bits (136), Expect = 2e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 2/106 (1%)
Query: 1511 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1568
L +V + + +WPF PV+ K +PDY+K+I PMD+ TI++ + + Y +
Sbjct: 82 LHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASEC 141
Query: 1569 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQL 1614
+ D N + N YN P AQ + + Q + + +L
Sbjct: 142 MQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQEL 187
Score = 43.1 bits (100), Expect = 0.003
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 1403 YPFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYN 1460
+PF PV+A + DY+KII +PMD+ T++ + Y + E + + N YN
Sbjct: 97 WPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Query: 1461 GPKHSLTQISQSM 1473
P + ++Q++
Sbjct: 157 KPTDDIVLMAQTL 169
Score = 31.6 bits (70), Expect = 7.6
Identities = 35/178 (19%), Positives = 70/178 (39%), Gaps = 11/178 (6%)
Query: 1173 DEEGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLR 1232
+EE E E R + + ++R ++ + R+ +KE+++ ++ +
Sbjct: 503 EEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEK 562
Query: 1233 RLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHM------RTNKFCPLYYQTN 1286
R E KGP +P + K+ G A+G + P
Sbjct: 563 HRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKT 622
Query: 1287 APPSNPVAMTEEQEEELEKTVIHNDNEELI----KVEGTKIVLGKQLIESADEVRRKS 1340
APP+ P E+EEE + + +++ +L K+ G K+ +I++ + R S
Sbjct: 623 APPALPTGYDSEEEEE-SRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDS 679
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 73.2 bits (178), Expect = 2e-12
Identities = 86/372 (23%), Positives = 150/372 (40%), Gaps = 77/372 (20%)
Query: 1510 ILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKVIVNPMDLETIRKNISKHKYQSRES 1567
IL ++++K A +WPF+ PV+ + DY+ +I +PMDL T+++ + Y+ +
Sbjct: 356 ILKELLSKKHAAY--AWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQE 413
Query: 1568 FLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALE 1627
F DV L+ +N KYN P+ A+++ +D+ + A +
Sbjct: 414 FAADVRLMFSNCYKYNPPDHDVVAMARKL-------------------QDVFEFRYAKMP 454
Query: 1628 EAELESLDPMTPGPY---TPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQ 1684
+ +P+ PGP T PP L +++ S +S E E++
Sbjct: 455 D------EPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEE-----------EEE 497
Query: 1685 VTQEGEDGDGDLADEEEGTVQ-----QPQASVLYEDL-LMSEG--EDDEEDAGSDEEGDN 1736
++ E+ + + +D EE Q Q ++E L +S+G + E+
Sbjct: 498 DEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKK 557
Query: 1737 PFSAIQLSESGSD-SDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLED 1795
+ +G+D D G RP QP+ +S + GG A+ G
Sbjct: 558 RKAEKHRGRAGADEDDKGPRAPRPPQPK-------------KSKKASGSGGGSAALGPSG 604
Query: 1796 SNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDE----EEEEQRS-------GPSVL 1844
S GS + PK T+ + GY+ EEEE +E+ Q S G +
Sbjct: 605 FGPSGGSGTKL-PKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLG 663
Query: 1845 SQVHLSEDEEDS 1856
VH+ + E S
Sbjct: 664 RVVHIIQAREPS 675
Score = 58.5 bits (140), Expect = 6e-08
Identities = 48/215 (22%), Positives = 95/215 (44%), Gaps = 25/215 (11%)
Query: 1280 PLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEV--- 1336
PL T APP+ P+A + + + + T I G+ L A +
Sbjct: 260 PLLAVTAAPPAQPLAKKKGVKRKADTTT---PTPTAILAPGSPASPPGSLEPKAARLPPM 316
Query: 1337 -RRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRR-TDPMVTLSSILESIIN 1394
R +K P++ LP +++ H+S + + ++ + + IL+ +++
Sbjct: 317 RRESGRPIKPPRKDLPDSQQQ--------------HQSSKKGKLSEQLKHCNGILKELLS 362
Query: 1395 DMRDLPNTYPFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELI 1452
+ +PF+ PV+A + DY+ II PMDL T++ + R Y +EF + L+
Sbjct: 363 K-KHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLM 421
Query: 1453 VKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDK 1487
N YN P H + +++ + D+ + + + D+
Sbjct: 422 FSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDE 456
Score = 57.0 bits (136), Expect = 2e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 2/106 (1%)
Query: 1511 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1568
L +V + + +WPF PV+ K +PDY+K+I PMD+ TI++ + + Y +
Sbjct: 82 LHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASEC 141
Query: 1569 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQL 1614
+ D N + N YN P AQ + + Q + + +L
Sbjct: 142 MQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQEL 187
Score = 43.1 bits (100), Expect = 0.003
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 1403 YPFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYN 1460
+PF PV+A + DY+KII +PMD+ T++ + Y + E + + N YN
Sbjct: 97 WPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Query: 1461 GPKHSLTQISQSM 1473
P + ++Q++
Sbjct: 157 KPTDDIVLMAQTL 169
Score = 31.6 bits (70), Expect = 7.6
Identities = 35/178 (19%), Positives = 70/178 (39%), Gaps = 11/178 (6%)
Query: 1173 DEEGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLR 1232
+EE E E R + + ++R ++ + R+ +KE+++ ++ +
Sbjct: 503 EEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEK 562
Query: 1233 RLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHM------RTNKFCPLYYQTN 1286
R E KGP +P + K+ G A+G + P
Sbjct: 563 HRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKT 622
Query: 1287 APPSNPVAMTEEQEEELEKTVIHNDNEELI----KVEGTKIVLGKQLIESADEVRRKS 1340
APP+ P E+EEE + + +++ +L K+ G K+ +I++ + R S
Sbjct: 623 APPALPTGYDSEEEEE-SRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDS 679
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 70.1 bits (170), Expect = 2e-11
Identities = 43/154 (27%), Positives = 72/154 (46%), Gaps = 14/154 (9%)
Query: 1511 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1568
+ N+V + + +WPF+ PV+ K +PDY+K+I NPMD+ TI+K + + Y S
Sbjct: 42 MQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASEC 101
Query: 1569 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQL---------EKDIC 1619
+ D N + N YN P AQ + + Q + + + +L K
Sbjct: 102 MQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAA 161
Query: 1620 TAKEAALEE-AELESLDPMTPGPYTPQPPDLYDT 1652
A+ A ++ A + S+ P T P+ PP + T
Sbjct: 162 GAQSAGTQQVAAVSSVSPAT--PFQSVPPTVSQT 193
Score = 59.7 bits (143), Expect = 3e-08
Identities = 29/92 (31%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 1510 ILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKVIVNPMDLETIRKNISKHKYQSRES 1567
IL ++++K A +WPF+ PV+ + + DY+ +I +PMDL T+++ + +Y +
Sbjct: 318 ILREMLSKKHAAY--AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
Query: 1568 FLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
F DV L+ +N KYN P+ + A+++ +V
Sbjct: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDV 407
Score = 57.4 bits (137), Expect = 1e-07
Identities = 29/103 (28%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
Query: 1390 ESIINDM---RDLPNTYPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREE 1444
+SI+ +M + +PF+ PV+A+ ++ DY+ II PMDL T++ + R YP +
Sbjct: 316 DSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
Query: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDK 1487
F + L+ N YN P H + +++ + D+ + + + D+
Sbjct: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 418
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Query: 1403 YPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYN 1460
+PF+ PV+A + DY+KII PMD+ T+++ + Y S E + + N YN
Sbjct: 57 WPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
Query: 1461 GPKHSLTQISQSMLDLCDEKLKE 1483
P + ++Q++ + +K+ +
Sbjct: 117 KPTDDIVLMAQALEKIFLQKVAQ 139
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 68.2 bits (165), Expect = 7e-11
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
Query: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K++Y E
Sbjct: 149 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207
Query: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1485
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 208 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
Score = 62.4 bits (150), Expect = 4e-09
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 1520 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1579
M P + F PV + PDY + I +PMDL T+ KN K Y E+FL D IL N
Sbjct: 160 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219
Query: 1580 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1608
+ YNG + T+ A+ ++ +C + E +
Sbjct: 220 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
Length = 1188
Score = 68.2 bits (165), Expect = 7e-11
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
Query: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K++Y E
Sbjct: 174 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
Query: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1485
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 233 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
Score = 62.4 bits (150), Expect = 4e-09
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 1520 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1579
M P + F PV + PDY + I +PMDL T+ KN K Y E+FL D IL N
Sbjct: 185 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
Query: 1580 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1608
+ YNG + T+ A+ ++ +C + E +
Sbjct: 245 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
Length = 1160
Score = 68.2 bits (165), Expect = 7e-11
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
Query: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K++Y E
Sbjct: 174 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
Query: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1485
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 233 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
Score = 62.4 bits (150), Expect = 4e-09
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 1520 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1579
M P + F PV + PDY + I +PMDL T+ KN K Y E+FL D IL N
Sbjct: 185 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
Query: 1580 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1608
+ YNG + T+ A+ ++ +C + E +
Sbjct: 245 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 66.6 bits (161), Expect = 2e-10
Identities = 30/92 (32%), Positives = 51/92 (55%)
Query: 1515 VTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNL 1574
+ Q++ + +WPF PV + P YY+VI PMDL+T+ + + Y S++ F+ D+
Sbjct: 735 ILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQR 794
Query: 1575 ILANSVKYNGPESQYTKTAQEIVNVCYQTLTE 1606
+ N +YN PES+Y K A + + + E
Sbjct: 795 VFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
Score = 58.5 bits (140), Expect = 6e-08
Identities = 30/99 (30%), Positives = 51/99 (51%)
Query: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
L S L+SI+ ++ + +PF PV YY++I PMDL+T+ E ++ R Y S++
Sbjct: 728 LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKL 787
Query: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1483
F L+ + N YN P+ + + + K+KE
Sbjct: 788 FMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 66.2 bits (160), Expect = 3e-10
Identities = 42/120 (35%), Positives = 62/120 (51%), Gaps = 14/120 (11%)
Query: 1475 DLCDEKLKE-------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP 1527
DL K++E K++ ++K P DD +A L +++ +M D+WP
Sbjct: 2032 DLKKRKMEENTSINLSKQESFTSVKK---PKRDDSKDLA----LCSMILTEMETHEDAWP 2084
Query: 1528 FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPES 1587
F PVN K VP Y KVI PMD TIR+ +S +Y + E+F DV L+ N +N +S
Sbjct: 2085 FLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDS 2144
Score = 58.5 bits (140), Expect = 6e-08
Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 2/128 (1%)
Query: 1353 KKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAK 1412
K+K T+++ S+ + + D L+ + I+ +M + +PF PVN K
Sbjct: 2035 KRKMEENTSINLSK-QESFTSVKKPKRDDSKDLA-LCSMILTEMETHEDAWPFLLPVNLK 2092
Query: 1413 VVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQS 1472
+V Y K+I +PMD T+RE + YP+ E F + L+ N T+N + + +
Sbjct: 2093 LVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHN 2152
Query: 1473 MLDLCDEK 1480
M ++K
Sbjct: 2153 MRKYFEKK 2160
Score = 38.5 bits (88), Expect = 0.062
Identities = 40/192 (20%), Positives = 73/192 (38%), Gaps = 25/192 (13%)
Query: 1594 QEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEE-AELESLDPMTPGPYTPQPPD---- 1648
Q ++ LT + +++ ++I A L + TPG TP P
Sbjct: 499 QSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPI 558
Query: 1649 LYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQPQ 1708
L+ ++S + + + + + + P K + ++ D D+ ++
Sbjct: 559 LHSQGKEKAVSNNVNPVKTQHH--------SHPAKSLVEQFRGTDSDIPSSKDS------ 604
Query: 1709 ASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQEN 1768
ED E EDDEE+ D+E D + S+S S+SD G Q+
Sbjct: 605 -----EDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDT-EGSEEEDDDDKDQDE 658
Query: 1769 TRMDMENEESMM 1780
+ D E E++ M
Sbjct: 659 SDSDTEGEKTSM 670
Score = 33.9 bits (76), Expect = 1.5
Identities = 52/220 (23%), Positives = 92/220 (41%), Gaps = 28/220 (12%)
Query: 1653 NTSLSMSRDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQPQASVL 1712
N S++ S +SV N SVL +++ Q T+ G G+ +E + QP
Sbjct: 170 NGSINGSNTSSVIG--INTSVLSTTASSSMGQ-TKSTSSGGGNRKCNQEQSKNQPL---- 222
Query: 1713 YEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMD 1772
D + + +D + + E N S +SG+ SD S GI L+E+ +
Sbjct: 223 --DARVDKIKDKKPRKKAMESSSNSDS-----DSGTSSDTSSEGISSSDSDDLEED---E 272
Query: 1773 MENEESMMSYEGDGGEA-SHGLEDSNISYGSYEEPDPKSNTQDTSFSS-----IGGYEVS 1826
E ++S+ E D ++ S SN + DPK++ Q + + ++
Sbjct: 273 EEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLA 332
Query: 1827 EEEEDEEEEEQRSGPSVLSQ-----VHLSEDEEDSEDFHS 1861
E + + Q+ P VLSQ S+ +E+S + H+
Sbjct: 333 SESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHT 372
Score = 31.2 bits (69), Expect = 9.9
Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 1183 ETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEK 1242
E +++A RI K++E R+ A+ + E R++ + + + K+ +EKE+
Sbjct: 973 EEAANAKLLEAEKRI---KEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKER 1029
Query: 1243 LKGPPEKKPKKMKER 1257
LK + + KER
Sbjct: 1030 LKQEKRDEKRLNKER 1044
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 64.7 bits (156), Expect = 8e-10
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Query: 1511 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1568
L +V + + SWPF PV+ K +PDYY +I NPMDL TI+K + Y
Sbjct: 35 LQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASEC 94
Query: 1569 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTE--YDEHLTQLEKDI--CTAKEA 1624
++D N + +N YN P AQ + + Q L++ +E + +++ I T +
Sbjct: 95 IEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNI 154
Query: 1625 ALEEAELESLDPMTPGPYTPQPPDLYDTNTSLS 1657
A+ A+ +S T + Q TS+S
Sbjct: 155 AVSSAKEKSSPSATEKVFKQQEIPSVFPKTSIS 187
Score = 59.3 bits (142), Expect = 3e-08
Identities = 32/94 (34%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 1508 SFILDNIVTQKMMAVPDSWPFHHPV--NKKFVPDYYKVIVNPMDLETIRKNISKHKYQSR 1565
S IL ++ +K + +WPF++PV N + +YY V+ NPMDL TI++ + +Y+
Sbjct: 277 SEILKEMLAKKHFSY--AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDA 334
Query: 1566 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
F DV L+ N KYN P+ + A+ + +V
Sbjct: 335 YKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
Score = 52.0 bits (123), Expect = 5e-06
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Query: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSR 1442
L + + ++ D+ ++PF PV+A ++ DYY II PMDL T+++ + + Y
Sbjct: 32 LQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKA 91
Query: 1443 EEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE--KEDKLARLEKAI 1495
E E + N YN P + ++Q++ L +KL + +E+++ +++ I
Sbjct: 92 SECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERI 146
Score = 50.1 bits (118), Expect = 2e-05
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRK 1436
T+ + S IL+ ++ + +PF+ PV NA + +YY ++ PMDL T++E +
Sbjct: 270 TEQLRHCSEILKEMLAK-KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDN 328
Query: 1437 RLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDL 1476
+ Y +F + L+ N YN P H + +++ + D+
Sbjct: 329 QEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 64.7 bits (156), Expect = 8e-10
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Query: 1511 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1568
L +V + + SWPF PV+ K +PDYY +I NPMDL TI+K + Y
Sbjct: 35 LQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASEC 94
Query: 1569 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTE--YDEHLTQLEKDI--CTAKEA 1624
++D N + +N YN P AQ + + Q L++ +E + +++ I T +
Sbjct: 95 IEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNI 154
Query: 1625 ALEEAELESLDPMTPGPYTPQPPDLYDTNTSLS 1657
A+ A+ +S T + Q TS+S
Sbjct: 155 AVSSAKEKSSPSATEKVFKQQEIPSVFPKTSIS 187
Score = 59.3 bits (142), Expect = 3e-08
Identities = 32/94 (34%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 1508 SFILDNIVTQKMMAVPDSWPFHHPV--NKKFVPDYYKVIVNPMDLETIRKNISKHKYQSR 1565
S IL ++ +K + +WPF++PV N + +YY V+ NPMDL TI++ + +Y+
Sbjct: 277 SEILKEMLAKKHFSY--AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDA 334
Query: 1566 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
F DV L+ N KYN P+ + A+ + +V
Sbjct: 335 YKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
Score = 52.0 bits (123), Expect = 5e-06
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Query: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSR 1442
L + + ++ D+ ++PF PV+A ++ DYY II PMDL T+++ + + Y
Sbjct: 32 LQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKA 91
Query: 1443 EEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE--KEDKLARLEKAI 1495
E E + N YN P + ++Q++ L +KL + +E+++ +++ I
Sbjct: 92 SECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERI 146
Score = 50.1 bits (118), Expect = 2e-05
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Query: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRK 1436
T+ + S IL+ ++ + +PF+ PV NA + +YY ++ PMDL T++E +
Sbjct: 270 TEQLRHCSEILKEMLAK-KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDN 328
Query: 1437 RLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDL 1476
+ Y +F + L+ N YN P H + +++ + D+
Sbjct: 329 QEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 62.8 bits (151), Expect = 3e-09
Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 1525 SWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKY 1582
+WPF PV+ K +PDYYK+I PMD+ TI+K + + Y + + + D N + N Y
Sbjct: 80 AWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY 139
Query: 1583 NGPESQYTKTAQEIVNVCYQTLTEYDEHLTQL-----------EKDICTAKE--AALEEA 1629
N P A+ + + Q + E T++ K+ TAK + +
Sbjct: 140 NKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNT 199
Query: 1630 ELESLDPMTPGPYTPQPPDLYDT 1652
S P T P P PP + T
Sbjct: 200 TQASTPPQTQTP-QPNPPPVQAT 221
Score = 57.4 bits (137), Expect = 1e-07
Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 20/164 (12%)
Query: 1508 SFILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKVIVNPMDLETIRKNISKHKYQSR 1565
S IL + +K A +WPF+ PV+ + + DY +I +PMD+ TI+ + +Y+
Sbjct: 358 SGILKEMFAKKHAAY--AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDA 415
Query: 1566 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAA 1625
+ F DV L+ +N KYN P+ + A+++ +V + +
Sbjct: 416 QEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE--------------- 460
Query: 1626 LEEAELESLDPMTPGP-YTPQPPDLYDTNTSLSMSRDASVFQDE 1668
EE + P P P PP D+++ S D+S E
Sbjct: 461 PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE 504
Score = 53.1 bits (126), Expect = 2e-06
Identities = 36/153 (23%), Positives = 70/153 (45%), Gaps = 16/153 (10%)
Query: 1337 RRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDM 1396
R S +K PK+ +P ++ P KS + ++ + S IL+ +
Sbjct: 322 RESSRPVKPPKKDVPDSQQHPA-----------PEKS--SKVSEQLKCCSGILKEMFAK- 367
Query: 1397 RDLPNTYPFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVK 1454
+ +PF+ PV+ + + DY II PMD+ T++ + R Y +EF + L+
Sbjct: 368 KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFS 427
Query: 1455 NSATYNGPKHSLTQISQSMLDLCDEKLKEKEDK 1487
N YN P H + +++ + D+ + + + D+
Sbjct: 428 NCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 460
Score = 47.4 bits (111), Expect = 1e-04
Identities = 33/137 (24%), Positives = 63/137 (45%), Gaps = 7/137 (5%)
Query: 1349 QLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTP 1408
Q P+ T + P+K +R+T+ L +L ++ + +PF P
Sbjct: 32 QAQPQPANAASTNPPPPETSNPNKP--KRQTNQ---LQYLLRVVLKTLWKHQFAWPFQQP 86
Query: 1409 VNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSL 1466
V+A + DYYKII PMD+ T+++ + Y + +E + + N YN P +
Sbjct: 87 VDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDI 146
Query: 1467 TQISQSMLDLCDEKLKE 1483
+++++ L +K+ E
Sbjct: 147 VLMAEALEKLFLQKINE 163
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 62.8 bits (151), Expect = 3e-09
Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 1525 SWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKY 1582
+WPF PV+ K +PDYYK+I PMD+ TI+K + + Y + + + D N + N Y
Sbjct: 80 AWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY 139
Query: 1583 NGPESQYTKTAQEIVNVCYQTLTEYDEHLTQL-----------EKDICTAKE--AALEEA 1629
N P A+ + + Q + E T++ K+ TAK + +
Sbjct: 140 NKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNT 199
Query: 1630 ELESLDPMTPGPYTPQPPDLYDT 1652
S P T P P PP + T
Sbjct: 200 TQASTPPQTQTP-QPNPPPVQAT 221
Score = 57.4 bits (137), Expect = 1e-07
Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 20/164 (12%)
Query: 1508 SFILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKVIVNPMDLETIRKNISKHKYQSR 1565
S IL + +K A +WPF+ PV+ + + DY +I +PMD+ TI+ + +Y+
Sbjct: 358 SGILKEMFAKKHAAY--AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDA 415
Query: 1566 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAA 1625
+ F DV L+ +N KYN P+ + A+++ +V + +
Sbjct: 416 QEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE--------------- 460
Query: 1626 LEEAELESLDPMTPGP-YTPQPPDLYDTNTSLSMSRDASVFQDE 1668
EE + P P P PP D+++ S D+S E
Sbjct: 461 PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE 504
Score = 53.1 bits (126), Expect = 2e-06
Identities = 36/153 (23%), Positives = 70/153 (45%), Gaps = 16/153 (10%)
Query: 1337 RRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDM 1396
R S +K PK+ +P ++ P KS + ++ + S IL+ +
Sbjct: 322 RESSRPVKPPKKDVPDSQQHPA-----------PEKS--SKVSEQLKCCSGILKEMFAK- 367
Query: 1397 RDLPNTYPFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVK 1454
+ +PF+ PV+ + + DY II PMD+ T++ + R Y +EF + L+
Sbjct: 368 KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFS 427
Query: 1455 NSATYNGPKHSLTQISQSMLDLCDEKLKEKEDK 1487
N YN P H + +++ + D+ + + + D+
Sbjct: 428 NCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 460
Score = 47.4 bits (111), Expect = 1e-04
Identities = 33/137 (24%), Positives = 63/137 (45%), Gaps = 7/137 (5%)
Query: 1349 QLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTP 1408
Q P+ T + P+K +R+T+ L +L ++ + +PF P
Sbjct: 32 QAQPQPANAASTNPPPPETSNPNKP--KRQTNQ---LQYLLRVVLKTLWKHQFAWPFQQP 86
Query: 1409 VNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSL 1466
V+A + DYYKII PMD+ T+++ + Y + +E + + N YN P +
Sbjct: 87 VDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDI 146
Query: 1467 TQISQSMLDLCDEKLKE 1483
+++++ L +K+ E
Sbjct: 147 VLMAEALEKLFLQKINE 163
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 62.8 bits (151), Expect = 3e-09
Identities = 54/263 (20%), Positives = 97/263 (36%), Gaps = 40/263 (15%)
Query: 1393 INDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELI 1452
IN + L F PV+ + Y ++ P DL T+++ + R Y + I
Sbjct: 1172 INQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYI 1231
Query: 1453 VKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE--DKLARLEKAINPLLDDDDQVAFSFI 1510
N+ T+N P + + ++ + DL +K++ + + +L D +
Sbjct: 1232 EHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDAD 1291
Query: 1511 LDNIVTQK--------------------------------MMAVPDSWPFHHPVNKKFVP 1538
+ T+K + DS PF PV+ P
Sbjct: 1292 VPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYP 1351
Query: 1539 DYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVN 1598
DY +I PMD T+R+ + Y+S DV LI +NS Y I +
Sbjct: 1352 DYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYT------PSKRSRIYS 1405
Query: 1599 VCYQTLTEYDEHLTQLEKDICTA 1621
+ + ++EH++ + D +A
Sbjct: 1406 MSLRLSAFFEEHISSVLSDYKSA 1428
Score = 45.4 bits (106), Expect = 5e-04
Identities = 26/76 (34%), Positives = 36/76 (47%)
Query: 1390 ESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHL 1449
E ++N + ++ PF PV+ DY II PMD T+RE + Y S E + +
Sbjct: 1326 EELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDV 1385
Query: 1450 ELIVKNSATYNGPKHS 1465
LI NS Y K S
Sbjct: 1386 RLIFSNSKAYTPSKRS 1401
Score = 45.1 bits (105), Expect = 7e-04
Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 20/140 (14%)
Query: 1518 KMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILA 1577
++M + + F PV+ + P Y V+ P DL TI++ + Y+ S + +V I
Sbjct: 1174 QLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEH 1233
Query: 1578 NSVKYNGPESQYTKTAQEIVNV---------CYQTLTEYDEHLTQLEKDICTAKEAALEE 1628
N+ +N P S K+A+ + ++ CY + Y+ + K+ L +
Sbjct: 1234 NTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYN-----------SMKKKVLSD 1282
Query: 1629 AELESLDPMTPGPYTPQPPD 1648
+E E D PG T + D
Sbjct: 1283 SEDEEKDADVPGTSTRKRKD 1302
Score = 31.2 bits (69), Expect = 9.9
Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 1214 EQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCG 1265
E +E + ++ Q+Q+++ K+ +EK GP K KK KER +L G
Sbjct: 878 ESSSDEEEESEKQKQKQIKKEKKKVNEEK-DGPISPKKKKPKERKQKRLAVG 928
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapiens]
Length = 1205
Score = 62.4 bits (150), Expect = 4e-09
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Query: 1480 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1539
+L K +KL R + + + + + F+ +L + P + F PVN VPD
Sbjct: 567 ELIRKREKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDP-AHIFAEPVNLSEVPD 625
Query: 1540 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTA 1593
Y + I PMD T+R+ + H Y++ E F +D NLI+ N +KYN ++ + + A
Sbjct: 626 YLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAA 679
Score = 57.4 bits (137), Expect = 1e-07
Identities = 60/284 (21%), Positives = 115/284 (40%), Gaps = 38/284 (13%)
Query: 1197 IRTTKDEEFIRKFALFDEQHREEMRKERRRIQ-------EQLRRLKRNQEKEKLKGPPEK 1249
I T DEE +++ +E+ EE+ +E + Q + + + + K+K+K PE+
Sbjct: 404 ISETGDEEGLKE-GDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEE 462
Query: 1250 KPKK---------MKERPDLKLKCGACGAIGHMRTNKFCPL---YYQTNAPPSNPVAMTE 1297
+ + + P +L C + R N+F Y+ N V +
Sbjct: 463 AGQDTPSTLPMLAVPQIPSYRLN-KICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIR 521
Query: 1298 EQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRR 1357
L+ E+ K K L K + ++ R L+++ +++
Sbjct: 522 RLHSHLQSQRNAEQREQDEKTSAVKEEL-KYWQKLRHDLERARLLIELIRKR-------- 572
Query: 1358 VGTTVHCDYLNRPHKSIHRRRTD-PMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKD 1416
+ L R + + + ++ + +L + ++ +++ + F PVN V D
Sbjct: 573 -------EKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPD 625
Query: 1417 YYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYN 1460
Y + I++PMD T+R + LY + EEF E LIV N YN
Sbjct: 626 YLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYN 669
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 61.6 bits (148), Expect = 7e-09
Identities = 32/102 (31%), Positives = 51/102 (50%)
Query: 1524 DSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYN 1583
DSWPF V+K VPDYY +I P+ L IR+ ++K +Y+ F+DD+ L+ +N +YN
Sbjct: 1418 DSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1477
Query: 1584 GPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAA 1625
+ K + + + H+T D + AA
Sbjct: 1478 PRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAA 1519
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Query: 1387 SILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFR 1446
S E ++ ++ +++PF V+ V DYY II +P+ L +RE V K Y EF
Sbjct: 1404 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1463
Query: 1447 EHLELIVKNSATYN 1460
+ +EL+ N YN
Sbjct: 1464 DDIELMFSNCFEYN 1477
Score = 39.7 bits (91), Expect = 0.028
Identities = 30/119 (25%), Positives = 62/119 (52%), Gaps = 5/119 (4%)
Query: 1138 SAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRI 1197
S A+ R ++ ++ A + L YR+ +E + ++ E ++ A A ++
Sbjct: 270 SPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKR 329
Query: 1198 RTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKE 1256
E +K +++ +E+ R+E ++I E+ RLK+ +EKE+LK EK+ +K++E
Sbjct: 330 EKADALEAKKK----EKEDKEKKREELKKIVEE-ERLKKKEEKERLKVEREKEREKLRE 383
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 1175 EGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLR-- 1232
E K+ + + +K + V K +E + + E+ RE++R+E+R+ E L+
Sbjct: 336 EAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQW 395
Query: 1233 -RLKRNQEKEKLKGPPEKKPKKMKERPDL 1260
+ + + E + LK PE P K + P++
Sbjct: 396 SKPREDMECDDLKELPEPTPVKTRLPPEI 424
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 20/85 (23%)
Query: 1758 RPKQ-PRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTS 1816
RPKQ R L R +E++E + E S G ED + +E + +S ++
Sbjct: 1164 RPKQRSRRLSSRQRPSLESDEDV--------EDSMGGEDDEVDG---DEEEGQSEEEE-- 1210
Query: 1817 FSSIGGYEVSEEEEDEEEEEQRSGP 1841
YEV ++E+D +EEE+ S P
Sbjct: 1211 ------YEVEQDEDDSQEEEEVSLP 1229
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 61.6 bits (148), Expect = 7e-09
Identities = 32/102 (31%), Positives = 51/102 (50%)
Query: 1524 DSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYN 1583
DSWPF V+K VPDYY +I P+ L IR+ ++K +Y+ F+DD+ L+ +N +YN
Sbjct: 1450 DSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
Query: 1584 GPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAA 1625
+ K + + + H+T D + AA
Sbjct: 1510 PRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAA 1551
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Query: 1387 SILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFR 1446
S E ++ ++ +++PF V+ V DYY II +P+ L +RE V K Y EF
Sbjct: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
Query: 1447 EHLELIVKNSATYN 1460
+ +EL+ N YN
Sbjct: 1496 DDIELMFSNCFEYN 1509
Score = 39.7 bits (91), Expect = 0.028
Identities = 30/119 (25%), Positives = 62/119 (52%), Gaps = 5/119 (4%)
Query: 1138 SAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRI 1197
S A+ R ++ ++ A + L YR+ +E + ++ E ++ A A ++
Sbjct: 270 SPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKR 329
Query: 1198 RTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKE 1256
E +K +++ +E+ R+E ++I E+ RLK+ +EKE+LK EK+ +K++E
Sbjct: 330 EKADALEAKKK----EKEDKEKKREELKKIVEE-ERLKKKEEKERLKVEREKEREKLRE 383
Score = 32.7 bits (73), Expect = 3.4
Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 1175 EGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLR-- 1232
E K+ + + +K + V K +E + + E+ RE++R+E+R+ E L+
Sbjct: 336 EAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQW 395
Query: 1233 -RLKRNQEKEKLKGPPEKKPKKMKERPDL 1260
+ + + E + LK PE P K + P++
Sbjct: 396 SKPREDMECDDLKELPEPTPVKTRLPPEI 424
Score = 32.0 bits (71), Expect = 5.8
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 20/85 (23%)
Query: 1758 RPKQ-PRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTS 1816
RPKQ R L R +E++E + E S G ED + +E + +S ++
Sbjct: 1196 RPKQRSRRLSSRQRPSLESDEDV--------EDSMGGEDDEVDG---DEEEGQSEEEE-- 1242
Query: 1817 FSSIGGYEVSEEEEDEEEEEQRSGP 1841
YEV ++E+D +EEE+ S P
Sbjct: 1243 ------YEVEQDEDDSQEEEEVSLP 1261
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 60.8 bits (146), Expect = 1e-08
Identities = 39/136 (28%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
Query: 1469 ISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPF 1528
I QS +L DE + + + PL + D + +L ++ KM +WPF
Sbjct: 2756 ILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYE-GLKRVLRSLQAHKM-----AWPF 2809
Query: 1529 HHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588
PV+ PDYY VI PMDL T+ + + + Y+ F+ D+ I N YN +S
Sbjct: 2810 LEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSP 2869
Query: 1589 YTKTAQEIVNVCYQTL 1604
+ + A+ + + Q L
Sbjct: 2870 FYQCAEVLESFFVQKL 2885
Score = 51.6 bits (122), Expect = 7e-06
Identities = 28/94 (29%), Positives = 44/94 (46%)
Query: 1389 LESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREH 1448
L+ ++ ++ +PF PV+ DYY +I PMDL T+ E V++R Y EF
Sbjct: 2793 LKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVAD 2852
Query: 1449 LELIVKNSATYNGPKHSLTQISQSMLDLCDEKLK 1482
+ I N YN Q ++ + +KLK
Sbjct: 2853 MTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2886
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 60.8 bits (146), Expect = 1e-08
Identities = 39/136 (28%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
Query: 1469 ISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPF 1528
I QS +L DE + + + PL + D + +L ++ KM +WPF
Sbjct: 2773 ILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYE-GLKRVLRSLQAHKM-----AWPF 2826
Query: 1529 HHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588
PV+ PDYY VI PMDL T+ + + + Y+ F+ D+ I N YN +S
Sbjct: 2827 LEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSP 2886
Query: 1589 YTKTAQEIVNVCYQTL 1604
+ + A+ + + Q L
Sbjct: 2887 FYQCAEVLESFFVQKL 2902
Score = 51.6 bits (122), Expect = 7e-06
Identities = 28/94 (29%), Positives = 44/94 (46%)
Query: 1389 LESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREH 1448
L+ ++ ++ +PF PV+ DYY +I PMDL T+ E V++R Y EF
Sbjct: 2810 LKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVAD 2869
Query: 1449 LELIVKNSATYNGPKHSLTQISQSMLDLCDEKLK 1482
+ I N YN Q ++ + +KLK
Sbjct: 2870 MTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 60.1 bits (144), Expect = 2e-08
Identities = 29/84 (34%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Query: 1523 PDSWPFHHPVNKKF--VPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSV 1580
P+S PF PV+ + +PDY+ ++ NPMDL TI++ + +YQ ++DDV L+ N+
Sbjct: 1068 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW 1127
Query: 1581 KYNGPESQYTKTAQEIVNVCYQTL 1604
YN S+ K ++ V Q +
Sbjct: 1128 LYNRKTSRVYKFCSKLAEVFEQEI 1151
Score = 44.7 bits (104), Expect = 9e-04
Identities = 39/195 (20%), Positives = 85/195 (43%), Gaps = 13/195 (6%)
Query: 1296 TEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVL----KFPKQQLP 1351
TE Q E+ E + E ++ + Q+ E D +KS + K P+ ++
Sbjct: 961 TETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE 1020
Query: 1352 PKKKRRV---GTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTP 1408
K++ GT ++P K I + P +++ ++ R P + PF P
Sbjct: 1021 VKEEEESSSNGTASQSTSPSQPRKKIFK----PEELRQALMPTLEALYRQDPESLPFRQP 1076
Query: 1409 VNAKV--VKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSL 1466
V+ ++ + DY+ I+ PMDL T++ + Y ++ + + L+ N+ YN +
Sbjct: 1077 VDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRV 1136
Query: 1467 TQISQSMLDLCDEKL 1481
+ + ++ ++++
Sbjct: 1137 YKFCSKLAEVFEQEI 1151
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 60.1 bits (144), Expect = 2e-08
Identities = 29/84 (34%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Query: 1523 PDSWPFHHPVNKKF--VPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSV 1580
P+S PF PV+ + +PDY+ ++ NPMDL TI++ + +YQ ++DDV L+ N+
Sbjct: 1106 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW 1165
Query: 1581 KYNGPESQYTKTAQEIVNVCYQTL 1604
YN S+ K ++ V Q +
Sbjct: 1166 LYNRKTSRVYKFCSKLAEVFEQEI 1189
Score = 44.7 bits (104), Expect = 9e-04
Identities = 39/195 (20%), Positives = 85/195 (43%), Gaps = 13/195 (6%)
Query: 1296 TEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVL----KFPKQQLP 1351
TE Q E+ E + E ++ + Q+ E D +KS + K P+ ++
Sbjct: 999 TETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE 1058
Query: 1352 PKKKRRV---GTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTP 1408
K++ GT ++P K I + P +++ ++ R P + PF P
Sbjct: 1059 VKEEEESSSNGTASQSTSPSQPRKKIFK----PEELRQALMPTLEALYRQDPESLPFRQP 1114
Query: 1409 VNAKV--VKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSL 1466
V+ ++ + DY+ I+ PMDL T++ + Y ++ + + L+ N+ YN +
Sbjct: 1115 VDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRV 1174
Query: 1467 TQISQSMLDLCDEKL 1481
+ + ++ ++++
Sbjct: 1175 YKFCSKLAEVFEQEI 1189
>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
[Homo sapiens]
Length = 2269
Score = 59.7 bits (143), Expect = 3e-08
Identities = 93/429 (21%), Positives = 160/429 (37%), Gaps = 69/429 (16%)
Query: 1393 INDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELI 1452
I+ + +L F PV+ Y ++ P DL T+R + R Y + I
Sbjct: 1173 IDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYI 1232
Query: 1453 VKNSATYNGPKHSLTQISQSMLDLCDEKLKE-KEDKLARLEKAINPL---------LDDD 1502
N+ T+N P+ + I++S + D+ LK K + + N LDD
Sbjct: 1233 EHNARTFNEPE---SVIARSAKKITDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDS 1289
Query: 1503 DQV-----------------AFSFILDNIVTQKMMAV------PDSWPFHHPVNKKFVPD 1539
D A +++ N Q V DS PF PV+ PD
Sbjct: 1290 DLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPD 1349
Query: 1540 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKY--NGPESQYTKTAQ--- 1594
Y +I PMD T+R+ + Y S F D+ LI +N+ Y N Y+ T +
Sbjct: 1350 YRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSA 1409
Query: 1595 ------EIVNVCYQTLTEYDEHL--TQLEKDICTAKEAALEEAELESLDPMTPGPYTPQP 1646
+ ++ ++ +++E L +Q K K + + +L P T
Sbjct: 1410 LFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKII 1469
Query: 1647 PDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQ 1706
P+L + T + SR A + ++ SA VT GD +D E + ++
Sbjct: 1470 PELVGSPTQSTSSRTAYLGTHKT--------SAGISSGVT------SGDSSDSAESSERR 1515
Query: 1707 PQASVLYEDLLMSEGEDDEE-----DAGSDEEGDNPFSAIQLSESGSDSDVG-SGGIRPK 1760
+ + +SE E ++ + + + + + ES S S + S +R
Sbjct: 1516 KRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVT 1575
Query: 1761 QPRMLQENT 1769
+ R Q T
Sbjct: 1576 RTRAAQRKT 1584
Score = 46.6 bits (109), Expect = 2e-04
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 1390 ESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHL 1449
+ ++N + ++ PF PV+ DY II PMD T+RE + Y S EF + +
Sbjct: 1323 KELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDI 1382
Query: 1450 ELIVKNSATYNGPKHS-LTQISQSMLDLCDEKLKE 1483
LI N+ Y K S + ++ + L +EK+K+
Sbjct: 1383 RLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKK 1417
>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
[Homo sapiens]
Length = 2320
Score = 59.7 bits (143), Expect = 3e-08
Identities = 93/429 (21%), Positives = 160/429 (37%), Gaps = 69/429 (16%)
Query: 1393 INDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELI 1452
I+ + +L F PV+ Y ++ P DL T+R + R Y + I
Sbjct: 1173 IDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYI 1232
Query: 1453 VKNSATYNGPKHSLTQISQSMLDLCDEKLKE-KEDKLARLEKAINPL---------LDDD 1502
N+ T+N P+ + I++S + D+ LK K + + N LDD
Sbjct: 1233 EHNARTFNEPE---SVIARSAKKITDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDS 1289
Query: 1503 DQV-----------------AFSFILDNIVTQKMMAV------PDSWPFHHPVNKKFVPD 1539
D A +++ N Q V DS PF PV+ PD
Sbjct: 1290 DLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPD 1349
Query: 1540 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKY--NGPESQYTKTAQ--- 1594
Y +I PMD T+R+ + Y S F D+ LI +N+ Y N Y+ T +
Sbjct: 1350 YRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSA 1409
Query: 1595 ------EIVNVCYQTLTEYDEHL--TQLEKDICTAKEAALEEAELESLDPMTPGPYTPQP 1646
+ ++ ++ +++E L +Q K K + + +L P T
Sbjct: 1410 LFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKII 1469
Query: 1647 PDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQ 1706
P+L + T + SR A + ++ SA VT GD +D E + ++
Sbjct: 1470 PELVGSPTQSTSSRTAYLGTHKT--------SAGISSGVT------SGDSSDSAESSERR 1515
Query: 1707 PQASVLYEDLLMSEGEDDEE-----DAGSDEEGDNPFSAIQLSESGSDSDVG-SGGIRPK 1760
+ + +SE E ++ + + + + + ES S S + S +R
Sbjct: 1516 KRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVT 1575
Query: 1761 QPRMLQENT 1769
+ R Q T
Sbjct: 1576 RTRAAQRKT 1584
Score = 46.6 bits (109), Expect = 2e-04
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 1390 ESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHL 1449
+ ++N + ++ PF PV+ DY II PMD T+RE + Y S EF + +
Sbjct: 1323 KELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDI 1382
Query: 1450 ELIVKNSATYNGPKHS-LTQISQSMLDLCDEKLKE 1483
LI N+ Y K S + ++ + L +EK+K+
Sbjct: 1383 RLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKK 1417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,030,261
Number of Sequences: 37866
Number of extensions: 4215248
Number of successful extensions: 32490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 205
Number of HSP's successfully gapped in prelim test: 499
Number of HSP's that attempted gapping in prelim test: 24556
Number of HSP's gapped (non-prelim): 5967
length of query: 1872
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1755
effective length of database: 13,817,196
effective search space: 24249178980
effective search space used: 24249178980
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.