Guide to the Human Genome
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Search of human proteins with 20336267

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20336267 ADP-ribosylation factor binding protein 3 isoform
long [Homo sapiens]
         (723 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo...  1439   0.0  
gi|14719400 ADP-ribosylation factor binding protein 3 isoform sh...  1355   0.0  
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b...   635   0.0  
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ...   382   e-106
gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]   346   4e-95
gi|239758145 PREDICTED: similar to ADP-ribosylation factor bindi...   141   2e-33
gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]           123   5e-28
gi|209180457 target of myb1 isoform 2 [Homo sapiens]                  108   1e-23
gi|4885637 target of myb1 isoform 1 [Homo sapiens]                    108   1e-23
gi|209180448 target of myb1 isoform 3 [Homo sapiens]                   96   9e-20
gi|48527954 golgi associated, gamma adaptin ear containing, ARF ...    95   3e-19
gi|191252812 target of myb1-like 1 [Homo sapiens]                      94   4e-19
gi|209180450 target of myb1 isoform 4 [Homo sapiens]                   82   2e-15
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i...    78   3e-14
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i...    78   3e-14
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]      76   1e-13
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]        75   2e-13
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H...    72   1e-12
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su...    71   3e-12
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         69   2e-11
gi|75677327 target of myb1-like 2 isoform 1 [Homo sapiens]             67   8e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   2e-08
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         57   5e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   7e-07
gi|54860079 nadrin isoform 1 [Homo sapiens]                            54   7e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    53   9e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  53   1e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   2e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             52   3e-06
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           51   4e-06

>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
           [Homo sapiens]
          Length = 723

 Score = 1439 bits (3726), Expect = 0.0
 Identities = 723/723 (100%), Positives = 723/723 (100%)

Query: 1   MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW 60
           MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW
Sbjct: 1   MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW 60

Query: 61  EALQALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYS 120
           EALQALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYS
Sbjct: 61  EALQALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYS 120

Query: 121 WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK 180
           WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK
Sbjct: 121 WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK 180

Query: 181 LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS 240
           LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS
Sbjct: 181 LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS 240

Query: 241 SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ 300
           SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ
Sbjct: 241 SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ 300

Query: 301 VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP 360
           VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP
Sbjct: 301 VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP 360

Query: 361 QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL 420
           QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL
Sbjct: 361 QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL 420

Query: 421 QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG 480
           QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG
Sbjct: 421 QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG 480

Query: 481 SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL 540
           SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL
Sbjct: 481 SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL 540

Query: 541 IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT 600
           IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT
Sbjct: 541 IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT 600

Query: 601 AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS 660
           AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS
Sbjct: 601 AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS 660

Query: 661 GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW 720
           GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW
Sbjct: 661 GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW 720

Query: 721 GNL 723
           GNL
Sbjct: 721 GNL 723


>gi|14719400 ADP-ribosylation factor binding protein 3 isoform short
           [Homo sapiens]
          Length = 690

 Score = 1355 bits (3506), Expect = 0.0
 Identities = 690/723 (95%), Positives = 690/723 (95%), Gaps = 33/723 (4%)

Query: 1   MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW 60
           MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW
Sbjct: 1   MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW 60

Query: 61  EALQALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYS 120
           EALQALT                                 YLGDRVSEKVKTKVIELLYS
Sbjct: 61  EALQALT---------------------------------YLGDRVSEKVKTKVIELLYS 87

Query: 121 WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK 180
           WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK
Sbjct: 88  WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK 147

Query: 181 LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS 240
           LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS
Sbjct: 148 LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS 207

Query: 241 SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ 300
           SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ
Sbjct: 208 SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ 267

Query: 301 VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP 360
           VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP
Sbjct: 268 VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP 327

Query: 361 QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL 420
           QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL
Sbjct: 328 QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL 387

Query: 421 QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG 480
           QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG
Sbjct: 388 QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG 447

Query: 481 SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL 540
           SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL
Sbjct: 448 SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL 507

Query: 541 IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT 600
           IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT
Sbjct: 508 IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT 567

Query: 601 AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS 660
           AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS
Sbjct: 568 AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS 627

Query: 661 GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW 720
           GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW
Sbjct: 628 GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW 687

Query: 721 GNL 723
           GNL
Sbjct: 688 GNL 690


>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 1 [Homo sapiens]
          Length = 639

 Score =  635 bits (1638), Expect = 0.0
 Identities = 367/729 (50%), Positives = 466/729 (63%), Gaps = 105/729 (14%)

Query: 5   EGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ 64
           E E+LE+ +N+ATNP N++ DW  I GFC+Q+N++ EGP +A RLLAHKIQSPQEWEA+Q
Sbjct: 6   EPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ 65

Query: 65  ALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMA 124
           ALTVLE CMK+CG+RFH+EVGKFRFLNELIKVVSPKYLG R SEKVK K++ELLYSWT+ 
Sbjct: 66  ALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVG 125

Query: 125 LPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKS 184
           LPEE KI +AY MLK+QGIV+SDP +P D T  P PPPRPKN +F+DEEKSK+LA+LLKS
Sbjct: 126 LPEEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKS 184

Query: 185 KNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGD 244
            +P+DL+ ANKLIK MV+ED+ R++K++KR++ +EEVNNNV+LL+EM++ +SQ  ++ G 
Sbjct: 185 SHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGS 244

Query: 245 RE-LMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVIN 303
            E LMKEL+ +CE  R TLF+LAS+TEDND +L +ILQA+DNL++VIN YK ++ G+ +N
Sbjct: 245 SEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGEEVN 304

Query: 304 GEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPPQAS 363
           G+    ++P S           L+DL+ LD        L PA T      P +P  P   
Sbjct: 305 GDATAGSIPGS--------TSALLDLSGLD--------LPPAGTT----YPAMPTRPGEQ 344

Query: 364 GPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQRE 423
             P   S+S              +S LD+EL+ LGL+DP P  P   S   + W+  Q  
Sbjct: 345 ASPEQPSAS--------------VSLLDDELMSLGLSDPTP--PSGPSLDGTGWNSFQ-- 386

Query: 424 QSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSL 483
                                           SS A  PP       PA   APS  S  
Sbjct: 387 --------------------------------SSDATEPP------APALAQAPSMES-- 406

Query: 484 FSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPT 543
                     P  + ++P        +S L  LD L + L +  +     +       PT
Sbjct: 407 ---------RPPAQTSLP-------ASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPT 450

Query: 544 -TTPARPLLPFSTGPGSPLFQPLSFQSQGS--PPKGP------ELSLASIHVPLESIKPS 594
                R L   S+   SP     S     S  PP+ P      ELSLASI VPLESIKPS
Sbjct: 451 PRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPS 510

Query: 595 SALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKV 654
           + LPVT YD++GFRILFHFA++  PGR DVLVVVVSML+TAP P+++IV Q+AVPK MKV
Sbjct: 511 NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKV 570

Query: 655 KLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQF 714
           KLQPPSGTEL  F+PI  P+AITQV+LLANP KEKVRLRYKLTF +G+Q   E+G+VDQF
Sbjct: 571 KLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQF 630

Query: 715 PPVEQWGNL 723
           PP E WG+L
Sbjct: 631 PPPETWGSL 639


>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 2 [Homo sapiens]
          Length = 552

 Score =  382 bits (980), Expect = e-106
 Identities = 182/274 (66%), Positives = 232/274 (84%), Gaps = 2/274 (0%)

Query: 5   EGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ 64
           E E+LE+ +N+ATNP N++ DW  I GFC+Q+N++ EGP +A RLLAHKIQSPQEWEA+Q
Sbjct: 6   EPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ 65

Query: 65  ALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMA 124
           ALTVLE CMK+CG+RFH+EVGKFRFLNELIKVVSPKYLG R SEKVK K++ELLYSWT+ 
Sbjct: 66  ALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVG 125

Query: 125 LPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKS 184
           LPEE KI +AY MLK+QGIV+SDP +P D T  P PPPRPKN +F+DEEKSK+LA+LLKS
Sbjct: 126 LPEEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKS 184

Query: 185 KNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGD 244
            +P+DL+ ANKLIK MV+ED+ R++K++KR++ +EEVNNNV+LL+EM++ +SQ  ++ G 
Sbjct: 185 SHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGS 244

Query: 245 RE-LMKELFDQCENKRRTLFKLASETEDNDNSLG 277
            E LMKEL+ +CE  R TLF+LAS+TEDND +LG
Sbjct: 245 SEDLMKELYQRCERMRPTLFRLASDTEDNDEALG 278



 Score =  226 bits (577), Expect = 4e-59
 Identities = 143/274 (52%), Positives = 170/274 (62%), Gaps = 24/274 (8%)

Query: 473 SVPAPSAGSSLFSTG------------VAPALA--PKVEPAVPGHHGLALGNSALHHLDA 518
           S P P +G SL  TG             APALA  P +E   P    L   +S L  LD 
Sbjct: 280 SDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLP-ASSGLDDLDL 338

Query: 519 LDQLLEEAKVTSGLVKPTTSPLIPTTT-PARPLLPFSTGPGSPLFQPLSFQSQGSP--PK 575
           L + L +  +     +       PT     R L   S+   SP     S     SP  P+
Sbjct: 339 LGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPR 398

Query: 576 GP------ELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVV 629
            P      ELSLASI VPLESIKPS+ LPVT YD++GFRILFHFA++  PGR DVLVVVV
Sbjct: 399 PPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVV 458

Query: 630 SMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEK 689
           SML+TAP P+++IV Q+AVPK MKVKLQPPSGTEL  F+PI  P+AITQV+LLANP KEK
Sbjct: 459 SMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEK 518

Query: 690 VRLRYKLTFALGEQLSTEVGEVDQFPPVEQWGNL 723
           VRLRYKLTF +G+Q   E+G+VDQFPP E WG+L
Sbjct: 519 VRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 552


>gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]
          Length = 613

 Score =  346 bits (888), Expect = 4e-95
 Identities = 207/476 (43%), Positives = 290/476 (60%), Gaps = 32/476 (6%)

Query: 8   SLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQALT 67
           SLE WLNKAT+PS  ++DW  I  FC+Q+N +  GP  A  LLAHKIQSPQE EAL ALT
Sbjct: 25  SLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALT 84

Query: 68  VLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALPE 127
           VLE CM +CG +FH+EV KFRFLNELIKV+SPKYLG   + KVK +VIE+L+SWT+  PE
Sbjct: 85  VLEMCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPE 144

Query: 128 EAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFD-DEEKSKLLAKLLKSKN 186
           + KI+DAY MLK+QGI++ DP +PVD+ ++P P P PK+ +FD DEEKSKLL +LLKS +
Sbjct: 145 DIKIRDAYQMLKKQGIIKQDPKLPVDK-ILPPPSPWPKSSIFDADEEKSKLLTRLLKSNH 203

Query: 187 PDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGDRE 246
           P+DLQ AN+LIK++VKE++ + +KV+KR+  +EEV ++V++L EML  Y +   +  D+E
Sbjct: 204 PEDLQAANRLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRPGQAPPDQE 263

Query: 247 LMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVINGEV 306
            ++ ++++CE  R TLF+LAS+T D+D++L +ILQA+D L++ +  YK ++EG+V  G  
Sbjct: 264 ALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNR 323

Query: 307 ATLTLPD------SEGNSQCSNQGTLIDLAELDTTNSLSSVLAPA---PTPPSSGIPILP 357
            T +L D       +  + C     LIDL E+D   +    + P+       + GI   P
Sbjct: 324 VTSSLGDIPVSRVFQNPAGCMKTCPLIDL-EVDNGPAQMGTVVPSLLHQDLAALGISDAP 382

Query: 358 PPPQASGPP-RSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAP---------NVP 407
                SG        + + +TL      N  +  D  LL L  A PAP         +VP
Sbjct: 383 VTGMVSGQNCCEEKRNPSSSTLPGGGVQNPSA--DRNLLDLLSAQPAPCPLNYVSQKSVP 440

Query: 408 PKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPP 463
            +   G         E   L   +P P      + + PL Q   P  S   + LPP
Sbjct: 441 KEVPPGTKSSPGWSWEAGPL---APSP-----SSQNTPLAQVFVPLESVKPSSLPP 488



 Score =  166 bits (421), Expect = 5e-41
 Identities = 90/181 (49%), Positives = 119/181 (65%), Gaps = 12/181 (6%)

Query: 541 IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT 600
           +P  T + P   +  GP +P     S  SQ +P       LA + VPLES+KPSS  P+ 
Sbjct: 443 VPPGTKSSPGWSWEAGPLAP-----SPSSQNTP-------LAQVFVPLESVKPSSLPPLI 490

Query: 601 AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS 660
            YD+NGFRIL HF++   PG P+V V++++M++TAP PV  I+ Q AVPKSM+VKLQP S
Sbjct: 491 VYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPAS 550

Query: 661 GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW 720
            ++L  FSP+ PPA I+Q++LL NP KE +RLRYKLTF  G Q  +EVGEV  FP +   
Sbjct: 551 SSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVL 610

Query: 721 G 721
           G
Sbjct: 611 G 611


>gi|239758145 PREDICTED: similar to ADP-ribosylation factor binding
           protein 2 [Homo sapiens]
          Length = 134

 Score =  141 bits (356), Expect = 2e-33
 Identities = 69/124 (55%), Positives = 91/124 (73%)

Query: 598 PVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQ 657
           P+  YD+NGFRIL HF++   PG P+V V++++M++TAP PV  I+ Q AVPKSM+VKLQ
Sbjct: 9   PLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQ 68

Query: 658 PPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPV 717
           P S ++L  FSP+ PPA I+Q++LL NP KE +RLRYKLTF  G Q  +EVGEV  FP +
Sbjct: 69  PASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDL 128

Query: 718 EQWG 721
              G
Sbjct: 129 AVLG 132


>gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]
          Length = 507

 Score =  123 bits (309), Expect = 5e-28
 Identities = 109/393 (27%), Positives = 179/393 (45%), Gaps = 45/393 (11%)

Query: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW-EALQALTVLEA 71
           L KAT+ S + EDW   +  CD IN+  EGP+ A+R L  ++   + + E + ALTVLE 
Sbjct: 17  LEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTVLET 76

Query: 72  CMKNCGRRFHNEVGKFRFLNE-LIKVVSPKYLGDRVSEKVKTKVIELLYSWTMAL---PE 127
           C+KNCG RFH  V    F++  L+K++SPK   +     V+ KV+ L+ +W  A    P+
Sbjct: 77  CVKNCGHRFHILVANRDFIDSVLVKIISPK---NNPPTIVQDKVLALIQAWADAFRSSPD 133

Query: 128 EAKIKDAYHMLKRQGI------VQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKL 181
              +   Y  LKR+G+      + +  PI   +  +P   P    P    ++++   A  
Sbjct: 134 LTGVVHIYEELKRKGVEFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQRTS--AGS 191

Query: 182 LKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHY--SQED 239
             S  P           S+     A  +++ +    L+ V  N +++SEML      QED
Sbjct: 192 YSSPPPAPYSAPQAPALSVTGPITANSEQIARLRSELDVVRGNTKVMSEMLTEMVPGQED 251

Query: 240 SSDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEG 299
           SS  D EL++EL   C   ++ + +L S    N+    ++L  +D+L+ V   Y+     
Sbjct: 252 SS--DLELLQELNRTCRAMQQRIVELISRV-SNEEVTEELLHVNDDLNNVFLRYERFERY 308

Query: 300 QVINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPP 359
           +             S  + Q ++ G L ++ E        +++   P  P+    ++ P 
Sbjct: 309 R-------------SGRSVQNASNGVLNEVTE-------DNLIDLGPGSPA----VVSPM 344

Query: 360 PQASGPPRSRSSSQAEATLGPSSTSNALSWLDE 392
              + PP S SS  A   LG  S S  LS L +
Sbjct: 345 VGNTAPPSSLSSQLAGLDLGTESVSGTLSSLQQ 377


>gi|209180457 target of myb1 isoform 2 [Homo sapiens]
          Length = 493

 Score =  108 bits (271), Expect = 1e-23
 Identities = 87/287 (30%), Positives = 140/287 (48%), Gaps = 19/287 (6%)

Query: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW-EALQALTVLEA 71
           + KAT+ S + EDW   +  CD IN+  EGP+ A+R +  +I   + + E + ALTVLE 
Sbjct: 17  IEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLET 76

Query: 72  CMKNCGRRFHNEVGKFRFLNE-LIKVVSPKYLGDRVSEKVKTKVIELLYSWTMAL---PE 127
           C+KNCG RFH  V    F+   L++ + PK   +     V  KV+ L+ SW  A    P+
Sbjct: 77  CVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSPD 133

Query: 128 EAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKS-KLLAKLLKSKN 186
              +   Y  L+R+G+       P+    + SP   P+  VF+ E +S +       S+ 
Sbjct: 134 LTGVVTIYEDLRRKGL-----EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQ 188

Query: 187 PDDLQEANKLIKSMVKEDEARI----QKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSD 242
            D  Q A  L    +   +  I    +++ K    LE V+ NVR++SEML       +  
Sbjct: 189 EDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEP 248

Query: 243 GDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRV 289
            D EL++EL   C   ++ + +L  +   N+    ++L  +DNL+ V
Sbjct: 249 ADLELLQELNRTCRAMQQRVLELIPQIA-NEQLTEELLIVNDNLNNV 294


>gi|4885637 target of myb1 isoform 1 [Homo sapiens]
          Length = 492

 Score =  108 bits (271), Expect = 1e-23
 Identities = 87/287 (30%), Positives = 140/287 (48%), Gaps = 19/287 (6%)

Query: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW-EALQALTVLEA 71
           + KAT+ S + EDW   +  CD IN+  EGP+ A+R +  +I   + + E + ALTVLE 
Sbjct: 17  IEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLET 76

Query: 72  CMKNCGRRFHNEVGKFRFLNE-LIKVVSPKYLGDRVSEKVKTKVIELLYSWTMAL---PE 127
           C+KNCG RFH  V    F+   L++ + PK   +     V  KV+ L+ SW  A    P+
Sbjct: 77  CVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSPD 133

Query: 128 EAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKS-KLLAKLLKSKN 186
              +   Y  L+R+G+       P+    + SP   P+  VF+ E +S +       S+ 
Sbjct: 134 LTGVVTIYEDLRRKGL-----EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQ 188

Query: 187 PDDLQEANKLIKSMVKEDEARI----QKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSD 242
            D  Q A  L    +   +  I    +++ K    LE V+ NVR++SEML       +  
Sbjct: 189 EDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEP 248

Query: 243 GDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRV 289
            D EL++EL   C   ++ + +L  +   N+    ++L  +DNL+ V
Sbjct: 249 ADLELLQELNRTCRAMQQRVLELIPQIA-NEQLTEELLIVNDNLNNV 294


>gi|209180448 target of myb1 isoform 3 [Homo sapiens]
          Length = 460

 Score = 96.3 bits (238), Expect = 9e-20
 Identities = 80/267 (29%), Positives = 129/267 (48%), Gaps = 19/267 (7%)

Query: 33  CDQINKELEGPQIAVRLLAHKIQSPQEW-EALQALTVLEACMKNCGRRFHNEVGKFRFLN 91
           CD IN+  EGP+ A+R +  +I   + + E + ALTVLE C+KNCG RFH  V    F+ 
Sbjct: 4   CDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVE 63

Query: 92  E-LIKVVSPKYLGDRVSEKVKTKVIELLYSWTMAL---PEEAKIKDAYHMLKRQGIVQSD 147
             L++ + PK   +     V  KV+ L+ SW  A    P+   +   Y  L+R+G+    
Sbjct: 64  SVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGL---- 116

Query: 148 PPIPVDRTLIPSPPPRPKNPVFDDEEKS-KLLAKLLKSKNPDDLQEANKLIKSMVKEDEA 206
              P+    + SP   P+  VF+ E +S +       S+  D  Q A  L    +   + 
Sbjct: 117 -EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDT 175

Query: 207 RI----QKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGDRELMKELFDQCENKRRTL 262
            I    +++ K    LE V+ NVR++SEML       +   D EL++EL   C   ++ +
Sbjct: 176 PIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQELNRTCRAMQQRV 235

Query: 263 FKLASETEDNDNSLGDILQASDNLSRV 289
            +L  +   N+    ++L  +DNL+ V
Sbjct: 236 LELIPQIA-NEQLTEELLIVNDNLNNV 261


>gi|48527954 golgi associated, gamma adaptin ear containing, ARF
          binding protein 1 isoform 3 [Homo sapiens]
          Length = 89

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 42/64 (65%), Positives = 54/64 (84%)

Query: 5  EGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ 64
          E E+LE+ +N+ATNP N++ DW  I GFC+Q+N++ EGP +A RLLAHKIQSPQEWEA+Q
Sbjct: 6  EPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ 65

Query: 65 ALTV 68
          ALTV
Sbjct: 66 ALTV 69


>gi|191252812 target of myb1-like 1 [Homo sapiens]
          Length = 476

 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 108/480 (22%), Positives = 209/480 (43%), Gaps = 93/480 (19%)

Query: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ-ALTVLEA 71
           + KAT    + EDW   +  CD IN   +GP+ AV+ L  +I      + +Q  L++++ 
Sbjct: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78

Query: 72  CMKNCGRRFHNEVGKFRFLNE-LIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALP---E 127
           C++NCG  F + + K  F+ E L+K+++P+Y    +   ++ +++  + +W+   P   +
Sbjct: 79  CVQNCGPSFQSLIVKKEFVKENLVKLLNPRY---NLPLDIQNRILNFIKTWSQGFPGGVD 135

Query: 128 EAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKSKNP 187
            +++K+ Y  L ++G+                 PP         +E +++      S NP
Sbjct: 136 VSEVKEVYLDLVKKGV---------------QFPPSEAEAETARQETAQI------SSNP 174

Query: 188 DDLQEANKLIKSMVKEDEARIQKVTK---RLHT-LEEVNNNVRLLSEMLLHYSQEDSSDG 243
                    + S++    + +  V +   +LH+ L+ V  NVR++S +L+  +    +  
Sbjct: 175 PTSVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHE 234

Query: 244 DRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVIN 303
           D EL+++L+      +  +  L    E+ D ++ +++Q +++L+  I  Y+     Q   
Sbjct: 235 DIELLQKLYKTGREMQERIMDLLVVVENEDVTV-ELIQVNEDLNNAILGYERFTRNQ--- 290

Query: 304 GEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPPQAS 363
                  L  ++   + +N           TT+         P+ PS  +  L P P+  
Sbjct: 291 ----QRILEQNKNQKEATN-----------TTSE--------PSAPSQDLLDLSPSPRM- 326

Query: 364 GPPRSRSSSQAEATLGPSST-SNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQR 422
             PR        ATLG  +T +N LS L+     L  +D   N+ P   + + Q +LL  
Sbjct: 327 --PR--------ATLGELNTMNNQLSGLN---FSLPSSDVTNNLKP---SLHPQMNLLAL 370

Query: 423 EQSDLDFFSPRPGTAACGA---------SDAPLLQP------SAPSSSSSQAPLPPPFPA 467
           E +++  F+ R       +         S++  LQP      +A  S+ S  PLP   PA
Sbjct: 371 ENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPA 430


>gi|209180450 target of myb1 isoform 4 [Homo sapiens]
          Length = 447

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 71/279 (25%), Positives = 118/279 (42%), Gaps = 48/279 (17%)

Query: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW-EALQALTVLEA 71
           + KAT+ S + EDW   +  CD IN+  EGP+ A+R +  +I   + + E + ALTVLE 
Sbjct: 17  IEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLET 76

Query: 72  CMKNCGRRFHNEVGKFRFLNE-LIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALPEEAK 130
           C+KNCG RFH  V    F+   L++ + PK   +     V  KV+ L+ +   +  +  +
Sbjct: 77  CVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQTVFNSETQSGQ 133

Query: 131 IKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKSKNPDDL 190
                   +++   Q   P+P    L    P  P                          
Sbjct: 134 DSVGTDSSQQEDSGQHAAPLPAPPILSGDTPIAPTP------------------------ 169

Query: 191 QEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGDRELMKE 250
                             +++ K    LE V+ NVR++SEML       +   D EL++E
Sbjct: 170 ------------------EQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQE 211

Query: 251 LFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRV 289
           L   C   ++ + +L  +   N+    ++L  +DNL+ V
Sbjct: 212 LNRTCRAMQQRVLELIPQIA-NEQLTEELLIVNDNLNNV 249


>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
           isoform a [Homo sapiens]
          Length = 825

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 23/195 (11%)

Query: 538 SPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPE-LSLASIHVPLESIKPSSA 596
           +P+IPT   ++P    S+  G  L         G+P   P   S+  I  P   +   S+
Sbjct: 641 TPVIPTAPTSKP----SSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSS 696

Query: 597 LP-----------VTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQ 645
            P           +TAY KNG +I F F +      P V V+ +   N+  L +   V Q
Sbjct: 697 QPLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQ 754

Query: 646 AAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLS 705
           AAVPK+ +++L  PS + +  F+       ITQV+ + NP K+++R+R KLT+       
Sbjct: 755 AAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAM 810

Query: 706 TEVGEVDQFPPVEQW 720
            ++ EV+ FPP + W
Sbjct: 811 QDLAEVNNFPP-QSW 824


>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
           isoform b [Homo sapiens]
          Length = 822

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 23/195 (11%)

Query: 538 SPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPE-LSLASIHVPLESIKPSSA 596
           +P+IPT   ++P    S+  G  L         G+P   P   S+  I  P   +   S+
Sbjct: 638 TPVIPTAPTSKP----SSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSS 693

Query: 597 LP-----------VTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQ 645
            P           +TAY KNG +I F F +      P V V+ +   N+  L +   V Q
Sbjct: 694 QPLFNDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQ 751

Query: 646 AAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLS 705
           AAVPK+ +++L  PS + +  F+       ITQV+ + NP K+++R+R KLT+       
Sbjct: 752 AAVPKTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAM 807

Query: 706 TEVGEVDQFPPVEQW 720
            ++ EV+ FPP + W
Sbjct: 808 QDLAEVNNFPP-QSW 821


>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
          Length = 525

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 95/400 (23%), Positives = 158/400 (39%), Gaps = 53/400 (13%)

Query: 10  ESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQALTVL 69
           E  + KATN  N  EDW  I+  CD++     G +  ++ +  ++       ALQALT+L
Sbjct: 10  EQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLL 69

Query: 70  EACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMAL---P 126
            AC+ NCG+ FH EV    F  E+  V+  K    +V EK+K+ ++E    W+      P
Sbjct: 70  GACVANCGKIFHLEVCSRDFATEVRAVIKNK-AHPKVCEKLKSLMVE----WSEEFQKDP 124

Query: 127 EEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKSKN 186
           + + I      +K +GI  + PP         +      N   +DE+ +K +   L+ + 
Sbjct: 125 QFSLISATIKSMKEEGI--TFPPAGSQTVSAAAKNGTSSNKNKEDEDIAKAIELSLQEQK 182

Query: 187 PDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLL--SEMLLHYSQEDSS--D 242
                E   L  S   +   ++ +  + L+  E V +N       E+++     D++   
Sbjct: 183 QQH-TETKSLYPSSEIQLNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWK 241

Query: 243 GDRELMKELFDQCENKRRTLFKLASETEDNDNSLGD---ILQASDNLSRVINSYKTIIEG 299
           G+      LF           +  +   D  N + D    ++ S+     I+  K     
Sbjct: 242 GENHRGIGLFPSNFVTTNLNIETEAAAVDKLNVIDDDVEEIKKSEPEPVYIDEDKMDRAL 301

Query: 300 QVINGEVATLTLPDSEG----NSQCSNQGTLID--LAELDTTNS---------------- 337
           QV+     T + PDS+        C   G +ID  L E+D  +S                
Sbjct: 302 QVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELY 361

Query: 338 ------------LSSVLAPAPTPP-SSGIPILPPPPQASG 364
                        S +  PA  PP SSG+P+   P Q+ G
Sbjct: 362 NKLVNEAPVYSVYSKLHPPAHYPPASSGVPMQTYPVQSHG 401


>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
          Length = 540

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 44/134 (32%), Positives = 71/134 (52%), Gaps = 9/134 (6%)

Query: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQALTVLEAC 72
           + KAT+  N  EDW  I+  CD++ +   GP+  +R +  ++       A+QALT+L AC
Sbjct: 13  VEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGAC 72

Query: 73  MKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMAL---PEEA 129
           + NCG+ FH EV    F +E+  V++  +   +V EK+K  ++E    WT      P+ +
Sbjct: 73  VSNCGKIFHLEVCSRDFASEVSNVLNKGH--PKVCEKLKALMVE----WTDEFKNDPQLS 126

Query: 130 KIKDAYHMLKRQGI 143
            I      LK QG+
Sbjct: 127 LISAMIKNLKEQGV 140


>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
           sapiens]
          Length = 785

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 15/200 (7%)

Query: 524 EEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLAS 583
           EEAK +    + + +  +PT   A  LL         L    S   Q  P   P    A 
Sbjct: 597 EEAKESKEAAQLSEAAPVPTEPQASQLLDLLD-----LLDGASGDVQHPPHLDPSPGGAL 651

Query: 584 IHV---PLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVK 640
           +H+   P     P+    +  +++ G ++   F +  PP  P +L++ ++  N +   V 
Sbjct: 652 VHLLDLPCVPPPPAPIPDLKVFEREGVQLNLSFIR--PPENPALLLITITATNFSEGDVT 709

Query: 641 SIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFAL 700
             + QAAVPKS++++LQ PSG  +    P +    ITQ+  + NP K  +RL+ +LT+  
Sbjct: 710 HFICQAAVPKSLQLQLQAPSGNTV----PARGGLPITQLFRILNPNKAPLRLKLRLTYDH 765

Query: 701 GEQLSTEVGEVDQFPPVEQW 720
             Q   E+ EV+   PVE W
Sbjct: 766 FHQSVQEIFEVNNL-PVESW 784


>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
           substrate [Homo sapiens]
          Length = 777

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 44/140 (31%), Positives = 71/140 (50%), Gaps = 8/140 (5%)

Query: 8   SLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQALT 67
           + E  L+KAT+    + DWE I+  CD I +     + AV  +  K+       AL AL 
Sbjct: 7   TFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALE 66

Query: 68  VLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALPE 127
           V+E+ +KNCG+  H+EV   + + EL        L  +V   V+ K++ L+ +W  A   
Sbjct: 67  VMESVVKNCGQTVHDEVANKQTMEEL-----KDLLKRQVEVNVRNKILYLIQAWAHAFRN 121

Query: 128 EAK---IKDAYHMLKRQGIV 144
           E K   ++D Y ++K +G V
Sbjct: 122 EPKYKVVQDTYQIMKVEGHV 141


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 118/395 (29%), Positives = 152/395 (38%), Gaps = 56/395 (14%)

Query: 342  LAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLAD 401
            LAPAP PPSSG+P +  P     P R  +      TLG +        L   LL L +  
Sbjct: 1327 LAPAPRPPSSGLPAVLNPRPTLTPGRLPT-----PTLGTARAPMPTPTLVRPLLKL-VHS 1380

Query: 402  PAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACG---ASDAPLLQP-----SAPS 453
            P+P V    + G +   +     S L   S  PG A+      + +PL  P     S P 
Sbjct: 1381 PSPEV-SASAPGAAPLTI----SSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPL 1435

Query: 454  SSSSQAPLPPPFPAP-----VVPASVP-APSAGSSLFSTGVAPALAPKVEPAVPGHHGLA 507
            SSS    +P   PAP      +P S P   SA      T V P LAP V PA PG   LA
Sbjct: 1436 SSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAP-VVPAAPGPPSLA 1494

Query: 508  LGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPG-SPLFQPLS 566
              + A     AL   L  A   S    P    L+  T+   P L  +  P  SP+  P S
Sbjct: 1495 -PSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS 1553

Query: 567  FQSQGSP-PKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVL 625
              +   P    P  + AS+  P  S   + A P+         IL       PP  P  L
Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAIL--APSPAPPLAP--L 1609

Query: 626  VVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS---GTELSPFSPIQPPAAI-----T 677
             V+      AP+   S   Q  VP      +  PS   GT L+  SP+  P  +     T
Sbjct: 1610 PVLAPSPGAAPVLASS---QTPVP------VMAPSSTPGTSLASASPVPAPTPVLAPSST 1660

Query: 678  QVMLLA---NPLKEKVRLRYKLTFALGEQLSTEVG 709
            Q ML A   +PL      +   T AL   L+  +G
Sbjct: 1661 QTMLPAPVPSPLPSPASTQ---TLALAPALAPTLG 1692



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 71/254 (27%), Positives = 99/254 (38%), Gaps = 34/254 (13%)

Query: 339  SSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLG 398
            +++LAP+P PP + +P+L P P A+  P   SS      + PSST             L 
Sbjct: 1595 TAILAPSPAPPLAPLPVLAPSPGAA--PVLASSQTPVPVMAPSSTPGT---------SLA 1643

Query: 399  LADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPG---TAACGASDAPLLQPSAPSSS 455
             A P P   P  +  ++Q  L     S L    P P    T A   + AP L  S+PS +
Sbjct: 1644 SASPVPAPTPVLAPSSTQTMLPAPVPSPL----PSPASTQTLALAPALAPTLGGSSPSQT 1699

Query: 456  SSQAPLPP--PFPA---PVVPASVPAPSAGSSLFSTGVAPALAP----KVEPAVPGHHGL 506
             S     P  PFP     + PAS   P+   +L S    P L P     + PA P     
Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTL-SLAPGPPLGPTQTLSLAPAPPLAPAS 1758

Query: 507  ALGNSALHHL-----DALDQLLEEAKVTSGLVKPTTSPLI-PTTTPARPLLPFSTGPGSP 560
             +G +  H L      +   LL  A V +  + P   P + P       L P ST   + 
Sbjct: 1759 PVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPAS 1818

Query: 561  LFQPLSFQSQGSPP 574
                L   + G+ P
Sbjct: 1819 QASSLVVSASGAAP 1832



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 84/359 (23%), Positives = 128/359 (35%), Gaps = 56/359 (15%)

Query: 334  TTNSLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEE 393
            T ++    L  + TPP     + P  P A GPP          +L PS  S + S     
Sbjct: 1464 TVSASGPALLTSVTPP-----LAPVVPAAPGPP----------SLAPSGASPSAS----- 1503

Query: 394  LLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPS 453
             L LGLA  AP++   ++ G+    LL    S +      PG     ++ AP   P    
Sbjct: 1504 ALTLGLAT-APSLSSSQTPGHPL--LLAPTSSHV------PGL---NSTVAPACSPVLVP 1551

Query: 454  SSSSQAPLPP-PFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSA 512
            +S+  +P P  P PAP   + +   S+ S   +T +AP  AP+     P           
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPV 1611

Query: 513  LHHLDALDQLLEEAKVTSGLVKPTTSP------LIPTTTPARPLLPFSTGPGSPLFQPLS 566
            L        +L  ++    ++ P+++P        P   P   L P ST    P   P  
Sbjct: 1612 LAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSP 1671

Query: 567  FQSQGSPPKGPELSLASIHVP-LESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVL 625
              S   P     L+LA    P L    PS  L +   +  G               P   
Sbjct: 1672 LPS---PASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQG-------------PFPTQT 1715

Query: 626  VVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLAN 684
            + +    +  P P +++ L    P      L       L+P SP+ P  A T  +  A+
Sbjct: 1716 LSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS 1774



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 73/266 (27%), Positives = 100/266 (37%), Gaps = 48/266 (18%)

Query: 335  TNSLSSVLAPAPTP---PSSGIPILPPPPQASGPPRSRSSSQAEA-----TLGPSSTSNA 386
            T+  S+   PAPTP   PSS   +LP P  +  P  + + + A A     TLG SS S  
Sbjct: 1640 TSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQT 1699

Query: 387  LSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPL 446
            LS        LG  +P    P +  +      L+           P P      A   PL
Sbjct: 1700 LS--------LGTGNPQGPFPTQTLSLTPASSLV-----------PTPAQTLSLAPGPPL 1740

Query: 447  LQPSAPSSSSSQAPLPPPFPA-PVVPAS------VPAPSAGSSLFSTGV-----APALAP 494
                 P+ + S AP PP  PA PV PA        PA S+ S L    V     +PA  P
Sbjct: 1741 ----GPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVP 1796

Query: 495  KVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFS 554
             + PA      LAL  ++     +    L  +   +  +  T    +P +      L   
Sbjct: 1797 TLGPAAA--QTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLR 1854

Query: 555  TGPGSPLFQPLSF---QSQGSPPKGP 577
            +GP SP     SF   + +  PP  P
Sbjct: 1855 SGPPSPPSTATSFGGPRPRRQPPPPP 1880



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 86/383 (22%), Positives = 144/383 (37%), Gaps = 79/383 (20%)

Query: 342  LAPAPTPPSSGI--PILPPP----PQASGPPRSRSSSQAEATLGPSSTSNALSWL----- 390
            L+PAP P SS +  P+  PP    P A+    S +++ A  T  P+ T      +     
Sbjct: 1116 LSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDM 1175

Query: 391  -----DEELLCLG-LADPAPNVPPKESAGNSQWHLLQREQSDLDFFS----------PRP 434
                   E++ +G LA  A    P  +AG S+    Q + + L              PRP
Sbjct: 1176 QARLPSGEVVSIGQLASLAQR--PVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRP 1233

Query: 435  ------GTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGV 488
                     + G     + QP+  +   + AP P P P  V+P+S P+ +   +  S   
Sbjct: 1234 LQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLS--- 1290

Query: 489  APALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPAR 548
             P  A +V P +  + G+              +++       GL            TP  
Sbjct: 1291 LPLAANQVPPTMVNNTGVV-------------KIVVRQAPRDGL------------TPVP 1325

Query: 549  PLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLES---IKP------SSALPV 599
            PL P    P S L   L+ +   +P + P  +L +   P+ +   ++P      S +  V
Sbjct: 1326 PLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEV 1385

Query: 600  TAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPL--PVKSIV---LQAAVPKSMKV 654
            +A       +        P   P      + + N++PL  PV S V   L +++P S+  
Sbjct: 1386 SASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPT 1445

Query: 655  KLQPPSGTELSPFSPIQPPAAIT 677
             L  P+   L+   PI  P  ++
Sbjct: 1446 TLPAPASAPLT--IPISAPLTVS 1466



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 47/172 (27%), Positives = 68/172 (39%), Gaps = 25/172 (14%)

Query: 441  ASDAPLLQPSAPSSSS---SQAPLP---PPFPAPVVPASVPAPSAGSSLFST--GVAPAL 492
            ASD PL +P     +S   ++A  P   P  P  +V A V APS  SS  S+  G +PA 
Sbjct: 2659 ASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPAR 2718

Query: 493  APKVEPAVP--------GHHGLALGNSALHHLDA-LDQLLEEAKVTSGL--VKPTTSPLI 541
             P+   +          G  G   G   L  L   L  ++EE ++       +   S L+
Sbjct: 2719 PPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLV 2778

Query: 542  PTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKP 593
            P  +        S  PGSP  + +S      P  GP  +  S  +P    +P
Sbjct: 2779 PGVSET------SASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQP 2824



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 65/267 (24%), Positives = 94/267 (35%), Gaps = 64/267 (23%)

Query: 342  LAPAPTPPSS----GIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCL 397
            + P+P PPS       P   PPP  + PP           + PSS            L L
Sbjct: 2481 ILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSP-----------LLL 2529

Query: 398  GLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSS 457
            G     P+VP   S  N    L  R +++L          A  + ++  L   A S +SS
Sbjct: 2530 G----PPSVPISASVTNLPLGL--RPEAEL-------CAQALASPESLELASVASSETSS 2576

Query: 458  QAPLPPPFPAPVVPASVP--------APSAGSSLFSTGVAP----------------ALA 493
             + +PP    PV    +P         PSA S     G  P                 + 
Sbjct: 2577 LSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVL 2636

Query: 494  PKVEP---AVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPL 550
            P+ E     V   +GL L  SA     A D+ L+E        +  T    PT++P +P 
Sbjct: 2637 PEGEELPLCVSESNGLELPPSA-----ASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQ 2691

Query: 551  LPFSTGPGSPLFQPLSFQSQGSPPKGP 577
               +    + +  P +  S  S P+GP
Sbjct: 2692 ELVT----AEVAAPSTSSSATSSPEGP 2714



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 24/150 (16%)

Query: 341  VLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLA 400
            V+   P  P   +P+ PPP    GP  S     A+ T GP         L   L+     
Sbjct: 1010 VVVNNPRAPLGPVPVRPPP----GPELS-----AQPTPGPVPQV-----LPASLMVSASP 1055

Query: 401  DPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAP 460
               P +P     G      LQ     L    P P     G S     +P  P+ S     
Sbjct: 1056 AGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTS-----RPPTPTLS----- 1105

Query: 461  LPPPFPAPVVPASVPAPSAGSSLFSTGVAP 490
            L P  PAPV  +  P P + S L    V P
Sbjct: 1106 LKPTPPAPVRLSPAPPPGSSSLLKPLTVPP 1135



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 40/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)

Query: 459  APLPPPFPAPV------VPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSA 512
            AP PPP P PV      +   VP     + +        L P      PG        SA
Sbjct: 980  APDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPE-----LSA 1034

Query: 513  LHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLL--PFSTGPGS---PLFQPLSF 567
                  + Q+L  + + S    P   PLIP + P  P+L  P     GS    L  PL  
Sbjct: 1035 QPTPGPVPQVLPASLMVS--ASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGV 1092

Query: 568  QSQGSPPKGPELSL 581
             S  S P  P LSL
Sbjct: 1093 LSGTSRPPTPTLSL 1106



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 63/294 (21%), Positives = 97/294 (32%), Gaps = 68/294 (23%)

Query: 432  PRPGTAACGASDAPLLQPSAPSSSSSQAPL---------------PPPFPAPVVPASVPA 476
            PRP  A+  A+   L+    P   S+  P+                PP P+ + P S PA
Sbjct: 2443 PRPTPASAPAAIPALV----PVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPA 2498

Query: 477  ---------------PSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQ 521
                           P A + L +      L P   P       L LG      L A   
Sbjct: 2499 CTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQAL 2558

Query: 522  LLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSL 581
               E+   + +    TS L  +  P + LLP +         P+S ++    P  P L+L
Sbjct: 2559 ASPESLELASVASSETSSL--SLVPPKDLLPVAVE-----ILPVSEKNLSLTPSAPSLTL 2611

Query: 582  ASIHVP--LESIKPSSA-------------LPVTAYDKNGFRILFHFAKECPPGRP---- 622
             +  +P   E   P SA             LP+   + NG  +    A + P   P    
Sbjct: 2612 EAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEAD 2671

Query: 623  ---DVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPP 673
               + L    +  ++   P + +  + A P +       P G      SP +PP
Sbjct: 2672 RTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGP-----SPARPP 2720


>gi|75677327 target of myb1-like 2 isoform 1 [Homo sapiens]
          Length = 457

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 90/383 (23%), Positives = 151/383 (39%), Gaps = 75/383 (19%)

Query: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW-EALQALTVLEA 71
           L KAT+ S + EDW   +  CD IN+  EGP+ A+R L  ++   + + E + ALT    
Sbjct: 17  LEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTAW-- 74

Query: 72  CMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALPEEAKI 131
                          FR   +L  VV        + E++K K +E   +   AL      
Sbjct: 75  ------------ADAFRSSPDLTGVV-------HIYEELKRKGVEFPMADLDALS----- 110

Query: 132 KDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKSKNPDDLQ 191
                            PI   +  +P   P    P    ++++   +       P    
Sbjct: 111 -----------------PIHTPQRSVPEVDPAATMPRSQSQQRTSAGSYSSPPPAPYSAP 153

Query: 192 EANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHY--SQEDSSDGDRELMK 249
           +A  L  S+     A  +++ +    L+ V  N +++SEML      QEDSS  D EL++
Sbjct: 154 QAPAL--SVTGPITANSEQIARLRSELDVVRGNTKVMSEMLTEMVPGQEDSS--DLELLQ 209

Query: 250 ELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVINGEVATL 309
           EL   C   ++ + +L S    N+    ++L  +D+L+ V   Y+     +         
Sbjct: 210 ELNRTCRAMQQRIVELISRV-SNEEVTEELLHVNDDLNNVFLRYERFERYR--------- 259

Query: 310 TLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPPQASGPPRSR 369
               S  + Q ++ G L ++ E        +++   P  P+    ++ P    + PP S 
Sbjct: 260 ----SGRSVQNASNGVLNEVTE-------DNLIDLGPGSPA----VVSPMVGNTAPPSSL 304

Query: 370 SSSQAEATLGPSSTSNALSWLDE 392
           SS  A   LG  S S  LS L +
Sbjct: 305 SSQLAGLDLGTESVSGTLSSLQQ 327


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 109/423 (25%), Positives = 155/423 (36%), Gaps = 73/423 (17%)

Query: 306 VATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSS-------GIPILPP 358
           +++L    S G+       + + ++   T  SL+S   PA TPP S        +P  PP
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468

Query: 359 PPQASGPPRSRSSS-------QAEATLGPSSTSNALSWL-------DEELLCLGLADPAP 404
              +  P  S  SS       QA ++L   S    LS L          L    L  P  
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528

Query: 405 NV--PPKESAGNSQWHLLQREQSDLDF----FSPRPGTAACGASDAPLL--QPSAPSSSS 456
           ++  PP E+  +     LQ   + L        P P      A  +PL    P  PSS +
Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588

Query: 457 SQAPLPPPFPA----------PVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGL 506
           +  P  PP  A          P+ P + P P A   L    + P  AP   PA P    L
Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL---ALPPLQAPPSPPASPPLSPL 645

Query: 507 ALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGS--PLFQP 564
           A  +      +AL   L +A  +     P  +P  P  +P  P+ P +T P    P    
Sbjct: 646 ATPSPQAP--NALAVHLLQAPFSPPPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLAA 701

Query: 565 LSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDV 624
              Q   SPP  P +S  S   P ++  P +A P+                + PP  P  
Sbjct: 702 PPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPL----------------QVPPSPP-- 742

Query: 625 LVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFS--PIQPPAAITQVMLL 682
                 M  +A  P +   L AA P  ++V   PP+   +SP +  P Q P A+    L 
Sbjct: 743 --ASPPMSPSATPPPRVPPLLAAPP--LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798

Query: 683 ANP 685
           A P
Sbjct: 799 ALP 801



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 90/323 (27%), Positives = 115/323 (35%), Gaps = 32/323 (9%)

Query: 334 TTNSLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSS-TSNALSWLDE 392
           TT  L +   PAP P  +     PP P  + PP + SS        P +  S  L  L  
Sbjct: 554 TTPHLETPPCPAPCPLQA-----PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608

Query: 393 ELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQP--S 450
             L   LA P P  PP  +    Q          L   +  P   A  A    LLQ   S
Sbjct: 609 PPLS-PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFS 666

Query: 451 APSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGN 510
            P S   QAP  PP   PV P++ P   A  SL      P   P   PA P      +  
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL---AAPPLQVPPSPPASP-----PMSP 718

Query: 511 SALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTP---ARPLL---PFSTGPGSPLFQP 564
           SA     A    L    +      P + P+ P+ TP     PLL   P    P  P   P
Sbjct: 719 SATPPPQA-PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777

Query: 565 LSFQSQGSPPKGPELSLASIHVPLESI-KPSSALPVTAYDKNGFRILFHFAKECPPGRPD 623
           +S  ++  P   P L+      PL+++  P ++ P  A       +        PP  P 
Sbjct: 778 MSPLAKPPPQAPPALATP----PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833

Query: 624 VLVVVVSMLNTAPLPVKSIVLQA 646
           VL     +L   P P  S  LQA
Sbjct: 834 VL--AAPLLQVPPSPPASPTLQA 854



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 80/346 (23%), Positives = 122/346 (35%), Gaps = 57/346 (16%)

Query: 337 SLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLC 396
           SL ++ +P  TPPS   P +  PP  + P        +  T+ P    ++L+        
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPP--------SLQTIPPIQVPHSLT-------- 396

Query: 397 LGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSS 456
                P+   PP   A       L   Q+     SP         + +P    ++ +S S
Sbjct: 397 ----SPSLQAPPSPLA-------LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445

Query: 457 SQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHL 516
             A  PP  P    P S+PA    S    T ++PA++P   P              +H L
Sbjct: 446 RPASTPPDSPPLQAPLSLPA----SPPLQTSLSPAVSPLSSPL------------TIHPL 489

Query: 517 DALDQLLE---EAKVTSGLVKP--TTSPLIPTTTPARPLLPFSTGP--GSPLFQPLSFQS 569
            AL  L     +A ++S ++ P  T S L P +    P    +T P    P   P   Q+
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP-ASLTTPPLENLPSLAPPPLQT 548

Query: 570 QGSPPKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVV 629
             +P   P L       P     P S L     +          A   P   P +    +
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS-----SIATPPPQAPPALASPPL 603

Query: 630 SMLNTAPL-PVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPA 674
             L + PL P+ +   QA    ++     PPS     P SP+  P+
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 84/358 (23%), Positives = 116/358 (32%), Gaps = 39/358 (10%)

Query: 334 TTNSLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSST-SNALSWLDE 392
           T ++ +S   PA  PP+SG     PP + + P    S  +A  T  P       L    E
Sbjct: 80  TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139

Query: 393 ELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAP 452
           E +  G A  A    PK SA ++         +  D   P PGT +       + + S  
Sbjct: 140 ETVARGKATEA----PKRSALSA--------GARRDTSGPTPGTPS-----PAMARRSRA 182

Query: 453 SSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSA 512
           + +    P P P   P  P   P  S  S+   +   P+ A +  P+  G        S 
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 513 LHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGP----GSPLFQPLSFQ 568
                 L           G  +    P  P     + L P    P     +P   PLS  
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302

Query: 569 SQGSP-PKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVV 627
              +P P G +     +  P  +  P   LP T             A   P   P     
Sbjct: 303 PLATPSPSGTK--ARPVPPPDNAATP---LPATLPPSPPLATPLPLAPPSPSAPPS---- 353

Query: 628 VVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANP 685
               L T P P  +   QA    +      PPS   L    PIQ P ++T   L A P
Sbjct: 354 ----LQTLPSPPATPPSQAPPSMTTPPMQAPPS---LQTIPPIQVPHSLTSPSLQAPP 404



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 89/362 (24%), Positives = 130/362 (35%), Gaps = 62/362 (17%)

Query: 354 PILPPPPQASGPPRSRSSSQAEATLGPS-------STSNALSWLDEELLCLG---LADPA 403
           P   P P   GP +S SS+   +T  PS       S    L       L      L+ PA
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 404 PNVPPKESAGNSQWHLLQREQSDLDFFSP-------RPGTAACGA-SDAPLLQPS----- 450
            + P       +  H  Q +   L    P       +    A G  S +PL  PS     
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 451 ---APSSSSSQAPLP---PPFP--APVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPG 502
               P   ++  PLP   PP P  A  +P + P+PSA  SL +    PA  P   P    
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP--- 370

Query: 503 HHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLF 562
               ++    +    +L Q +   +V   L  P+     P +  A   L  +T  GSP  
Sbjct: 371 ----SMTTPPMQAPPSL-QTIPPIQVPHSLTSPSLQ--APPSPLALSSLQATTSLGSPTL 423

Query: 563 QPL-SFQSQGSPPKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGR 621
           Q   SF +    P+  + SL S   P  +  P  + P+ A            +    P  
Sbjct: 424 QATHSFLTMS--PRQTQASLTSPSRPAST--PPDSPPLQA----------PLSLPASPPL 469

Query: 622 PDVLVVVVSMLNTA----PLPVKSIVLQAAVPKSMKVKLQPPSGTE--LSPFSPIQPPAA 675
              L   VS L++     PL   S +   +    +   + PP  T+  L+P S   PPA+
Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529

Query: 676 IT 677
           +T
Sbjct: 530 LT 531



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 80/302 (26%), Positives = 99/302 (32%), Gaps = 73/302 (24%)

Query: 343 APAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSN-------ALSWLD---- 391
           A  P  PS+  P   PPP A+ P +   S  A   + PS+T         A   L     
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771

Query: 392 --EELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASD------ 443
               L    LA P P  PP  +    Q   L    +     +P   +A+   S       
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQ--ALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 444 -------APLLQ--PSAPSSSSSQAPLPPPFPAP------------VVPASVPAPSAGSS 482
                  APLLQ  PS P+S + QAP  PP P P            + P   P PS   S
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889

Query: 483 LFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIP 542
              +G          P + GH   A   S    L   D   E     S    P     + 
Sbjct: 890 STLSG----------PDLAGHSSSA--TSTPEELRGYDSGPEGGAAAS----PPPDAELA 933

Query: 543 TTTPA------RPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSA 596
              PA       P L F   PG+PL  P        P  GP  S   +    E+  P SA
Sbjct: 934 ACHPAAWSRGPAPPLAFRGAPGAPLPWP--------PATGPG-SADGLCTIYETEGPESA 984

Query: 597 LP 598
            P
Sbjct: 985 TP 986



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 55/205 (26%), Positives = 70/205 (34%), Gaps = 34/205 (16%)

Query: 338  LSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCL 397
            L+  LAP P PP    P   P    SGP  +  SS A      +ST   L   D      
Sbjct: 872  LTLALAPGPPPP----PSRSPSSTLSGPDLAGHSSSA------TSTPEELRGYDSGPEGG 921

Query: 398  GLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSS 457
              A P P+     +   + W              P P  A  GA  APL  P A    S+
Sbjct: 922  AAASPPPDA-ELAACHPAAWSR-----------GPAPPLAFRGAPGAPLPWPPATGPGSA 969

Query: 458  QA----------PLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGL- 506
                            P P  + P   P  S G +    G A A +   + A  G   L 
Sbjct: 970  DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG-AGASSRSPKQARLGELPLG 1028

Query: 507  ALGNSALHHLDALDQLLEEAKVTSG 531
            AL  S + HL +   LL  A+  +G
Sbjct: 1029 ALQASVVQHLLSRTLLLAAAEGAAG 1053


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 103/361 (28%), Positives = 134/361 (37%), Gaps = 81/361 (22%)

Query: 365 PPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQ 424
           P RSR  + A      S    +   L   L  LGL  P P      S  +  ++LL    
Sbjct: 384 PRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGP------SHSDGSFNLLGS-- 435

Query: 425 SDLDFFSPRPGTAACGASDAPL--LQPSAPSSSSSQ------APLPPPFP-APVVPASV- 474
              D   P P T + G+   P   +QPS P ++S        AP PP    APVVP+ V 
Sbjct: 436 ---DAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVL 492

Query: 475 PAPSAGSSLFSTGVAPALAP----KVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTS 530
            +PS G  +   G A  L P    +  P      GLAL  +          +L    +  
Sbjct: 493 QSPSEGLGM-GAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF------PGMLGALPLPL 545

Query: 531 GLVKPTTSPLIPTTT-----------PARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPEL 579
            L +P  SPL+  +            P  PLLP   GPG PL            P+GP L
Sbjct: 546 SLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPL--------APGEPEGPSL 597

Query: 580 SLASIHVP----------------LESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPD 623
            +AS+  P                L S  P  AL  TA D  G           P G P 
Sbjct: 598 LVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSA----EGAGGPSGEPF 653

Query: 624 VLVVVVSMLNTAPL--PVKSIVLQAAVPKSMKVKLQPPSGTE-----LSPFSPIQPPAAI 676
             +  +S L   PL  P   I L +A+   +   L PPSGT      LS   P  P +++
Sbjct: 654 SGLGDLSPLLFPPLSAPPTLIALNSAL---LAATLDPPSGTPPQPCVLSAPQPGPPTSSV 710

Query: 677 T 677
           T
Sbjct: 711 T 711



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 66/276 (23%), Positives = 96/276 (34%), Gaps = 45/276 (16%)

Query: 339 SSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTS------NALSWLDE 392
           S  L P P PPS+ +P  P P  AS PP S ++      LGP   +       A  +L  
Sbjct: 264 SDALTPPPLPPSNNLPAHPGP--ASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLAS 321

Query: 393 ELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQ---P 449
            LL        P +PP  +    +        S      P         +   LL+   P
Sbjct: 322 SLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGP 381

Query: 450 SAPSSSSSQAPLPPPFP-------APVVPA-------SVPAPSAGSSLF----------- 484
             P  S  +AP P P P        P++P+         P PS     F           
Sbjct: 382 QTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPP 441

Query: 485 ----STGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL 540
               S+G  P     ++P++PG    +L  S++    A     +   V S +++  +  L
Sbjct: 442 PPTLSSGSPPQPRHPIQPSLPGTTSGSL--SSVPGAPAPPAASKAPVVPSPVLQSPSEGL 499

Query: 541 IPTTTPARPLLPFSTGPGSPLFQP---LSFQSQGSP 573
                PA PL P + G   P   P   L+    G P
Sbjct: 500 GMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFP 535



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 69/263 (26%), Positives = 86/263 (32%), Gaps = 45/263 (17%)

Query: 340 SVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPS------------------ 381
           S L P P+ P S +     P  A GP        AE   GPS                  
Sbjct: 608 SDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL 667

Query: 382 STSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGA 441
           S    L  L+  LL   L DP    PP+                     +P+PG      
Sbjct: 668 SAPPTLIALNSALLAATL-DPPSGTPPQPCV----------------LSAPQPGPPTSSV 710

Query: 442 SDAPLLQPSAPS--SSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPA 499
           + A    P A S   + S +  PP   +P++ AS+      S   S G  P+L     P 
Sbjct: 711 TTA-TTDPGASSLGKAPSNSGRPPQLLSPLLGASL-LGDLSSLTSSPGALPSLLQPPGPL 768

Query: 500 VPGHHGLAL--GNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGP 557
           + G  GL L  G  A   L      L  A +   L  P   P  P   P  P       P
Sbjct: 769 LSGQLGLQLLPGGGAPPPLSEASSPL--ACLLQSLQIPPEQPEAPCLPPESPASALEPEP 826

Query: 558 GSPLFQPLSFQSQGSP-PKGPEL 579
             P    L+    GSP P  PEL
Sbjct: 827 ARPPLSALA-PPHGSPDPPVPEL 848



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 57/226 (25%), Positives = 79/226 (34%), Gaps = 32/226 (14%)

Query: 400 ADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQ- 458
           A P   VPP          L     S    F   P  A  G    P L    PS  SS  
Sbjct: 145 ARPPCRVPPTTPLNGGPGSLPPEPPSVSQAF---PTLAGPGGLFPPRLADPVPSGGSSSP 201

Query: 459 -------APLPPPFPAPVVPASVPAPSAGSSLFSTGVAPAL----APKVEPAVPGHHGLA 507
                  AP P P P P +  + P+ + G++L S+ V   L    AP    + P    L 
Sbjct: 202 RFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL- 260

Query: 508 LGNSALHHLDAL-DQLLEEAKVTSGLVKPTTSPLIPTTTPARPLL-------PFSTGPGS 559
                 H  DAL    L  +        P + P + + T   PL+       P   GPG+
Sbjct: 261 -----FHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGA 315

Query: 560 PLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVTAYDKN 605
           P F   S  S  +  + P L   S    L+  +P +  P  ++  +
Sbjct: 316 PPFLASSLLSAAAKAQHPPLPPPS---TLQGRRPRAQAPSASHSSS 358



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 77/280 (27%), Positives = 92/280 (32%), Gaps = 60/280 (21%)

Query: 354 PILPPP-----PQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPP 408
           P+LPPP     P A G P     S   A+L P   S+ L              P P+ PP
Sbjct: 575 PLLPPPGGPGPPLAPGEPEG--PSLLVASLLPPPPSDLL--------------PPPSAPP 618

Query: 409 KESAGNSQWHLLQREQSDLDFFSPRPGTAA------CGASD-APLLQP--SAP------S 453
                 S   LL    +  D      G          G  D +PLL P  SAP      +
Sbjct: 619 SNLLA-SFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALN 677

Query: 454 SSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSAL 513
           S+   A L PP   P  P  + AP  G    S   A           PG   L    S  
Sbjct: 678 SALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATT--------DPGASSLGKAPSNS 729

Query: 514 HHLDALDQLLEEAKVTSGLVKPTTSP--LIPTTTPARPLLPFSTG----PGSPLFQPLS- 566
                L   L  A +   L   T+SP  L     P  PLL    G    PG     PLS 
Sbjct: 730 GRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSE 789

Query: 567 --------FQSQGSPPKGPELSLASIHVPLESIKPSSALP 598
                    QS   PP+ PE        P  +++P  A P
Sbjct: 790 ASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARP 829



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 43/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 343 APAPTPPSSGIPILPPPPQASG----------PPRSRSSSQAEATLGPSSTSNALSWLDE 392
           AP P PP+S +      P AS           PP+  S     + LG  S+  +      
Sbjct: 700 APQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALP 759

Query: 393 ELLC---------LGLAD-PAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGAS 442
            LL          LGL   P    PP  S  +S    L +    L     +P        
Sbjct: 760 SLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQS---LQIPPEQP-------- 808

Query: 443 DAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTG 487
           +AP L P +P+S+    P  PP  A   P   P P     L   G
Sbjct: 809 EAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRG 853


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 75/271 (27%), Positives = 97/271 (35%), Gaps = 37/271 (13%)

Query: 337 SLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLC 396
           S S +  P+P+ P S  P  PP  Q    P +   SQA  +LG  +     S+L    L 
Sbjct: 291 SSSPLATPSPSAPPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348

Query: 397 LGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQP--SAPSS 454
             LA P P  PP  +    Q          L   +  P   A  A    LLQ   S P S
Sbjct: 349 -PLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFSPPPS 406

Query: 455 SSSQAPLPPPFPAPVVPASVPAPSAGSSLF--------STGVAPALAPKVEPAVPGHHGL 506
              QAP  PP   PV P++ P   A  SL         S   +P ++P   P       L
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466

Query: 507 ALGNSALHHLDALDQLLEEAKVTSGLVKPTTS--PLIPTTTPAR-PLLPFSTGPGSPLFQ 563
           A           L       +    L  P     P  P + P + P  P ++ P SPL  
Sbjct: 467 A--------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518

Query: 564 PLSFQSQGSPPKGPELSLASIHVPLESIKPS 594
           P        PP+ P +  A    PL  + PS
Sbjct: 519 P--------PPQAPPVLAA----PLLQVPPS 537



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 75/273 (27%), Positives = 94/273 (34%), Gaps = 52/273 (19%)

Query: 346 PTPPSSGIPILPPPPQAS-----GPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLA 400
           P+PP S  P+  PPPQA       P ++  S  A   L P                  LA
Sbjct: 343 PSPPLS--PLATPPPQAPPALALPPLQAPPSPPASPPLSP------------------LA 382

Query: 401 DPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSS-SSQA 459
            P+P  P   +      HLLQ        FSP P          P   P +PS++  SQA
Sbjct: 383 TPSPQAPNALAV-----HLLQAP------FSPPPSPPVQAPFSPPASPPVSPSATPPSQA 431

Query: 460 P---LPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHG-LALGNSALHH 515
           P     PP   P  P + P  S  ++       P  AP ++ A P      AL    L  
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491

Query: 516 LDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLL--PFSTGPGSPLFQPLSFQSQGSP 573
           L +           S       SPL      A P+L  P    P SP   P     +  P
Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551

Query: 574 PKGPE---------LSLASIHVPLESIKPSSAL 597
             GP+         L+LA    P  S  PSS L
Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 79/293 (26%), Positives = 99/293 (33%), Gaps = 65/293 (22%)

Query: 339 SSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLG 398
           S  ++P+ TPPS   P L  PP    P     S  A   + PS+T    +        L 
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPP-----SPPASPPMSPSATPPPQAPPPLAAPPLQ 472

Query: 399 LADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASD-------------AP 445
           LA P P  PP  +    Q   L    +     +P   +A+   S              AP
Sbjct: 473 LAKPPPQAPPALATPPLQ--ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530

Query: 446 LLQ--PSAPSSSSSQAPLPPPFPAP------------VVPASVPAPSAGSSLFSTGVAPA 491
           LLQ  PS P+S + QAP  PP P P            + P   P PS   S   +G    
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---- 586

Query: 492 LAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPA---- 547
                 P + GH   A   S    L   D   E     S    P     +    PA    
Sbjct: 587 ------PDLAGHSSSA--TSTPEELRGYDSGPEGGAAAS----PPPDAELAACHPAAWSR 634

Query: 548 --RPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALP 598
              P L F   PG+PL  P        P  GP  S   +    E+  P SA P
Sbjct: 635 GPAPPLAFRGAPGAPLPWP--------PATGPG-SADGLCTIYETEGPESATP 678



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 83/343 (24%), Positives = 110/343 (32%), Gaps = 64/343 (18%)

Query: 354 PILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAG 413
           P   P P   GP +S SS+   +T                       +P+P    + SAG
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHST----------------------TEPSPAARRRPSAG 222

Query: 414 NSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPAS 473
                 LQR           P + +  +S  PL  P+    S+   P  P  P+   P  
Sbjct: 223 GG----LQR-----------PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 267

Query: 474 VPA---PSAGSSLFSTGVAPALAP-KVEPAVPGHHGLALGNSALHHLDALDQ--LLEEAK 527
           + A   P           APAL P    P            SA   L  L        ++
Sbjct: 268 LQALRPPQVTPP--RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325

Query: 528 VTSGLVKPTTSPLIPTTTPARPLLPFSTGP--GSPLFQPLSFQSQGSPPKGPELSLASIH 585
            T+ L  PT      +  P+ PL P +T P    P       Q+  SPP  P LS     
Sbjct: 326 ATTSLGSPTLQ-ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS----- 379

Query: 586 VPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQ 645
            PL +  P +         N   +    A   PP  P V     S   + P+   +    
Sbjct: 380 -PLATPSPQA--------PNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPVSPSATPPS 429

Query: 646 AAVPKSMKVKLQ-PPSGTELSPFSPIQPPAAITQVMLLANPLK 687
            A P      LQ PPS     P SP   P       L A PL+
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 75/339 (22%), Positives = 108/339 (31%), Gaps = 50/339 (14%)

Query: 348 PPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSST-SNALSWLDEELLCLGLADPAPNV 406
           PP+SG     PP + + P    S  +A  T  P       L    EE +  G A  A   
Sbjct: 85  PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA--- 141

Query: 407 PPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFP 466
            PK SA ++         +  D   P PGT +       + + S  + +    P P P  
Sbjct: 142 -PKRSALSA--------GARRDTSGPTPGTPS-----PAMARRSRAAGTEVGLPRPAPSA 187

Query: 467 APVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEA 526
            P  P   P  S  S+   +   P+ A +  P+  G        S       L       
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247

Query: 527 KVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHV 586
               G  +    P  P     + L P    P          +   +P  GP LS + +  
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPP---------RKDAAPALGP-LSSSPLAT 297

Query: 587 PLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRP----------DVLVVVVSMLNTAP 636
           P  S  PS + P +                 PP  P            L    S L + P
Sbjct: 298 PSPSAPPSPSAPPSLQ-----------TLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346

Query: 637 L-PVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPA 674
           L P+ +   QA    ++     PPS     P SP+  P+
Sbjct: 347 LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 55/205 (26%), Positives = 70/205 (34%), Gaps = 34/205 (16%)

Query: 338 LSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCL 397
           L+  LAP P PP    P   P    SGP  +  SS A      +ST   L   D      
Sbjct: 564 LTLALAPGPPPP----PSRSPSSTLSGPDLAGHSSSA------TSTPEELRGYDSGPEGG 613

Query: 398 GLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSS 457
             A P P+     +   + W              P P  A  GA  APL  P A    S+
Sbjct: 614 AAASPPPDA-ELAACHPAAWSR-----------GPAPPLAFRGAPGAPLPWPPATGPGSA 661

Query: 458 QA----------PLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGL- 506
                           P P  + P   P  S G +    G A A +   + A  G   L 
Sbjct: 662 DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG-AGASSRSPKQARLGELPLG 720

Query: 507 ALGNSALHHLDALDQLLEEAKVTSG 531
           AL  S + HL +   LL  A+  +G
Sbjct: 721 ALQASVVQHLLSRTLLLAAAEGAAG 745


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 83/334 (24%), Positives = 131/334 (39%), Gaps = 45/334 (13%)

Query: 283 SDNLSRVINSYKTIIEGQVINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVL 342
           S  L R   +   ++EG ++  E   + L D + + +    GTL           +S   
Sbjct: 474 SGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRR---GGTL-------NRKHISPAF 523

Query: 343 APAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADP 402
            P P PP+ G  ++P  P+   PP+   SS+AE++ G  +  ++   L++         P
Sbjct: 524 QP-PLPPTDGSTVVPAGPEP--PPQ---SSRAESSSGGGTVPSSAGILEQG------PSP 571

Query: 403 APNVPPK-ESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQP---SAPSSSSSQ 458
               PPK +   ++      R  S +     +P  AA G+    + QP   + PS  + +
Sbjct: 572 GDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQP-QAAAGSHQLSMGQPHNAAGPSPHTLR 630

Query: 459 APLPPPFPAPVVPASVPA--PSAGSSLFSTGVAPALAPKVEPAVPG----HHGLALGNSA 512
             +  P PAP  P + P   P   SS  ++   P+L+PK     P     H G   G  +
Sbjct: 631 RAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPS 690

Query: 513 LHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTP---ARPLL---PFSTGPGSPLFQPLS 566
                A  QL    + +S L  P  +P  P   P   A PL+   P S GP +P+  P  
Sbjct: 691 -----APSQLSAPRRYSSSL-SPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSE 744

Query: 567 FQSQGSPPKGPELSLASIHVPLESIKPSSALPVT 600
              +      P+        PL    PS   P T
Sbjct: 745 HGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQT 778



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 38/156 (24%), Positives = 51/156 (32%), Gaps = 38/156 (24%)

Query: 335 TNSLSSVLAP---APTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLD 391
           ++SLS + AP    P PP+   P++   P + GPP   +         PS T        
Sbjct: 702 SSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQ----- 756

Query: 392 EELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSA 451
                       P+ PP           L ++   L    P P T A G        P  
Sbjct: 757 --------TPTPPSTPP-----------LGKQNPSL----PAPQTLAGG-------NPET 786

Query: 452 PSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTG 487
               +   P P P P P    SVP P     + S G
Sbjct: 787 AQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAG 822


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 90/378 (23%), Positives = 126/378 (33%), Gaps = 71/378 (18%)

Query: 344  PAPTPPSSGIPILPPPPQ------ASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCL 397
            PA TPPS    +  PPP+      A+ PP  +      +  G  +T  A     +     
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG---- 1207

Query: 398  GLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSS 457
            GLA P+P   P   A                  SP+ G A      AP    + P S   
Sbjct: 1208 GLATPSPKGAPTTPAATPP--------------SPKGGLATPSPKGAPTTPAATPPSPKG 1253

Query: 458  QAPLPPPFPAPVVPASVPAPSAGSSLF--------STGVAPALAPKVEPAVPGHHGLALG 509
                PPP  AP  PA+ P PS    L         +  V    +PK  PA     G    
Sbjct: 1254 GPATPPPKGAPTPPAATP-PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312

Query: 510  NSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTP----ARPLLPFST-----GPGSP 560
             +A              K + G   P  +P  P  TP      P LP +T     GP +P
Sbjct: 1313 PAATP---------PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363

Query: 561  LFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECP-- 618
                 S +   +PP           +   S K   A+P    D     ++    K+ P  
Sbjct: 1364 -----SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418

Query: 619  ---------PGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSP 669
                     P + D+    V+ ++    P  S         S K     P+   ++P SP
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK---GDPTLPAVTPPSP 1475

Query: 670  IQPPAAITQVMLLANPLK 687
             +PPA   QV   ++P K
Sbjct: 1476 KEPPAP-KQVATSSSPKK 1492



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 85/355 (23%), Positives = 109/355 (30%), Gaps = 63/355 (17%)

Query: 332  LDTTNSLSSVLAPAPTPPS-SGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWL 390
            L T +   +   PA TPPS  G P  PPP  A  PP +           P S    L+  
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT----------PPSLKGGLATP 1281

Query: 391  DEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPS 450
              +    G  +PA   PP                      SP+ G A      AP    +
Sbjct: 1282 PHK----GAPNPAVVTPP----------------------SPKGGPATSPPKGAPTPPAA 1315

Query: 451  APSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAP--KVEPAVP-GHHGLA 507
             P S       PPP  AP  PA  P    G     T   PA  P  K  P  P    G  
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKG-----TPTLPATTPSSKGGPTTPSSKEGPT 1370

Query: 508  LGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSF 567
               +   H           K    +  P   P  P   P  P    +T        P++ 
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT--------PVTR 1422

Query: 568  QSQGSPPKGPELSLASIHVPLESIKPSS------ALPVTAYDKNGFRILFHFAKECPPGR 621
            +   +P KG     A   V L+    +S      A P +  D     +     KE P  +
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482

Query: 622  PDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAI 676
                          P P+ +  L A +P S K     PS    S   PI P A +
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS----SRRDPIAPTATL 1533



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 83/353 (23%), Positives = 123/353 (34%), Gaps = 77/353 (21%)

Query: 334  TTNSLSSVLAPAPTPPSSGIPILPPPPQASGP----PRSRSSSQAEATLGPSSTSNALSW 389
            T +S      PA TP   G P + PP    GP    P+   +S A   L P         
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA------ 1415

Query: 390  LDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDF------FSPRPGTAACGASD 443
                        PA  V  + +A  S+  L     + +         +P+ G A   +  
Sbjct: 1416 ------------PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 444  APLL---------QPSAP-----SSSSSQAP-LPPPFPAPVVPASVPAPSAGSSLFSTGV 488
             P L         +P AP     SSS  +AP  P P  AP +PA +P+            
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS------------ 1511

Query: 489  APALAPKVEPAVPGHHGLALGNSA--LHHLDALDQLLEEAKVTSGLV--KPTTSPLIPT- 543
                +PK  PA P      +  +A  L          +EA +   +    P  +P IPT 
Sbjct: 1512 ----SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567

Query: 544  -TTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVTAY 602
               PA P    ++ P  P   P +++   SP +       +   P E+  P +  P +  
Sbjct: 1568 KEAPATPSSKEASSP--PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP- 1624

Query: 603  DKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIV--LQAAVPKSMK 653
            +K         A   P G P    V  S L  +P    S+   + A VP++ K
Sbjct: 1625 EKGP-------ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 62/233 (26%), Positives = 77/233 (33%), Gaps = 54/233 (23%)

Query: 344  PAPTPPS-SGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADP 402
            PA TPPS  G P  P P  A  PP         A   PS                GLA P
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPP---------AATPPSPKG-------------GLATP 1120

Query: 403  APNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLP 462
                 P   A                  SP+ G A      AP    + P S       P
Sbjct: 1121 PHKGAPTTPAATPP--------------SPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166

Query: 463  PPFPAPVVPASV-PAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQ 521
            PP  AP  PA+  P+P  G +  S   AP       P+  G  GLA  +           
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG--GLATPSP---------- 1214

Query: 522  LLEEAKVTSGLVKPTTSPLIPTTTP-ARPLLPFSTGPGSPLFQPLSFQSQGSP 573
              + A  T     P+    + T +P   P  P +T P SP   P +   +G+P
Sbjct: 1215 --KGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGPATPPPKGAP 1264



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 78/341 (22%), Positives = 104/341 (30%), Gaps = 68/341 (19%)

Query: 344  PAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPA 403
            PA TP S G P  P   +   PP +  S +    + P S               G A P+
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR------------GPAIPS 1397

Query: 404  PN----------VPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPS 453
            P           + PK++             S  D   P     +   + A       P+
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457

Query: 454  SSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSAL 513
            + SS+     P   P  P   PAP          VA + +PK  PA P   G        
Sbjct: 1458 TPSSKGDPTLPAVTPPSPKEPPAPKQ--------VATSSSPKKAPATPAPMGAPT----- 1504

Query: 514  HHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSP 573
              L A+  +    K           P+ PT T      P +  P   L  P    +  SP
Sbjct: 1505 --LPAV--IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA--MTVPSP 1558

Query: 574  PKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLN 633
             K P     +I  P E+       P T   K             PP       V  S   
Sbjct: 1559 KKTP-----AIPTPKEA-------PATPSSKEA---------SSPPA------VTPSTYK 1591

Query: 634  TAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPA 674
             AP P + ++  A    S K    PP+ T  SP      PA
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA 1632



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 54/218 (24%), Positives = 81/218 (37%), Gaps = 45/218 (20%)

Query: 449 PSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLAL 508
           P APS  ++ APL     AP +P SVP+PS         + PA  P     V G      
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPS---------LPPAGTPPGTKKVDG------ 753

Query: 509 GNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQ 568
               + H  AL  +    K       PT       T  ++  L +     SPL   +S Q
Sbjct: 754 ----ISHTSALAPVASSPKEC-----PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804

Query: 569 SQGSPPK----GPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDV 624
           ++  P K    GP+  + ++  P+  ++ +S LP  +       + F  +K+ P      
Sbjct: 805 TKRPPTKKGSAGPDTPIGNLSSPVSPVE-ASFLPENS-------LSFQGSKDSP------ 850

Query: 625 LVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGT 662
                +   T P P  +    A  P S K    PP  T
Sbjct: 851 ---ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKET 885



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 81/371 (21%), Positives = 127/371 (34%), Gaps = 55/371 (14%)

Query: 325  TLIDLAELDTTNSLSSVLAPAPTPPS-SGIPILPPPPQASGPPRSRSSSQAEATLGPSST 383
            TL+      T     +++ PA T PS    P +P P +A   P S+ +S   A   PS+ 
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT-PSTY 1590

Query: 384  SNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASD 443
              A S   E L+   +  P+P   P   A                  SP  G A      
Sbjct: 1591 KGAPS-PKELLIPPAVTSPSPKEAPTPPAVTPP--------------SPEKGPATPAPKG 1635

Query: 444  APLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG-------SSLFSTGVAPALAPKV 496
             P   P  PSS    +P  P      + A+VP  S G       ++L    VAPA  P+ 
Sbjct: 1636 TPTSPPVTPSSLKD-SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA--PES 1692

Query: 497  EPAV--PGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTT---------- 544
             P +  P   G     S+            +      L     +PL+P            
Sbjct: 1693 TPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGK 1752

Query: 545  ----TPARPLLPFSTGPGSPLFQ-------PLSFQSQGSPPKGPELSLASIHVPLESIKP 593
                +P  PL P  +   +PL         P    +  S    P +SL     P+ ++ P
Sbjct: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP 1812

Query: 594  SSA-LPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSM 652
                LP +     G  +        P    ++L ++     +  +P +S+++    PKS 
Sbjct: 1813 KQQFLPSSP----GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSA 1868

Query: 653  KVKLQPPSGTE 663
             + +  PS  +
Sbjct: 1869 GIPVPTPSAKQ 1879



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 96/432 (22%), Positives = 145/432 (33%), Gaps = 90/432 (20%)

Query: 289 VINSYKTIIEGQVINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAP-APT 347
           V+ +  TI        EVAT   P                ++ ++ T+  + V+AP AP 
Sbjct: 442 VVTNPCTIAAAPTTTFEVATCVSPPMSSGP----------ISNIEPTSPAALVMAPVAPK 491

Query: 348 PPSSG------IPILPPPPQASGP-----------PRSRSSSQAEATL--GPSSTSNALS 388
            PS+       IP+ PP P                P  +      A+L   P S + A  
Sbjct: 492 EPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGL 551

Query: 389 WLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDL---DFFSPRPGTAACGASDAP 445
              ++   L L   AP   P   + +S   +    ++ L       P P      +  +P
Sbjct: 552 TTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSP 611

Query: 446 LLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGS----SLFSTGVAPALAP------- 494
           L   S+ S   + +   P    P++ +S+  P+  +    S    GVAP  A        
Sbjct: 612 LGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTT 671

Query: 495 KVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFS 554
              P + G   LA  N                 V  G +  TT PL+PT +   P+ P  
Sbjct: 672 TASPFLEGTVSLAPKNHP---------------VKEGTL--TTLPLVPTASENCPVAPSP 714

Query: 555 TGPGSPLFQ-------PLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVTAYDKNGF 607
               +PL         P S  S   PP G       +    + I  +SAL   A      
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV----DGISHTSALAPVASS---- 766

Query: 608 RILFHFAKECPPGRPDVLVV-----VVSMLNTAPLPV-KSIVLQAAVPKSMKVKLQP--P 659
                  KECP               ++ L  +P P+  S+  Q   P + K    P  P
Sbjct: 767 ------PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820

Query: 660 SGTELSPFSPIQ 671
            G   SP SP++
Sbjct: 821 IGNLSSPVSPVE 832



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 84/341 (24%), Positives = 107/341 (31%), Gaps = 61/341 (17%)

Query: 342  LAPAPTPPSSGI--------PILPPPPQASGPPRSRSS-SQAEATLGPSSTSNALSWLDE 392
            L P  TP  S +        P  P P QA     + SS  +A AT  P            
Sbjct: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP-------- 931

Query: 393  ELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAP 452
                   A P+P   P   A                  SP+ G A      AP    + P
Sbjct: 932  -------ASPSPKGAPTPPAATPP--------------SPKGGPATPSPKWAPTPPAATP 970

Query: 453  SSSSSQAPLPPPFPAPVVPASV-PAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNS 511
             S       P P  AP  PA+  P+P  G +  S   AP   P V P  P       G+ 
Sbjct: 971  PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT-PPAVTPPSP------KGSP 1023

Query: 512  ALHHLDALDQLLEEAKVTSGLVKPTTSPLI--PTTTPARPLLPFSTGPGSPLFQPLSFQS 569
            A             A   S    P  +PL     TTPA  L     GP +P  +      
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 570  QGSP--PKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVV 627
              +P  PKG   + +    P+    P +A P +   K G     H   +  P  P     
Sbjct: 1084 AATPPSPKGGPATPSPKGAPM----PPAATPPS--PKGGLATPPH---KGAPTTPAATPP 1134

Query: 628  VVSMLNTAPLPVKSIVLQAAVPKSMK--VKLQPPSGTELSP 666
                    P P  +    AA P S K  +   PP G   +P
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 62/277 (22%), Positives = 96/277 (34%), Gaps = 39/277 (14%)

Query: 421 QREQSDLDFFSPRPGTAACGASDAPLLQPSAP-------SSSSSQAPLPPPFPAPVVPAS 473
           Q E + L   S    TAA G     L  P +P       S+++  +P P P      P  
Sbjct: 20  QAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLE 79

Query: 474 VPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLV 533
           VP P + S    T +    AP+    +P   G  +  +AL              + S ++
Sbjct: 80  VPFPQSSS---GTALPLGTAPEAPTFLPNLIGPPISPAAL-------------ALASPMI 123

Query: 534 KPTTSPLIPTTTPARPLLPFSTGP----GSPLFQPLSFQSQGSPPKGPELSLASIHVPLE 589
            PT   L  T + + PL   +  P     S  F P    S  S       S+ ++  P+ 
Sbjct: 124 APT---LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180

Query: 590 SIK--------PSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKS 641
             +        PS  +P      +   I+      C      +   V S+  T P    +
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA 240

Query: 642 IVL-QAAVPKSMKVKLQPPSGTELSPFSPIQPPAAIT 677
           I   Q        V + P +   LS   P+ PPAA++
Sbjct: 241 IASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALS 277



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 85/402 (21%), Positives = 140/402 (34%), Gaps = 73/402 (18%)

Query: 342 LAPAPTPPSSGIP--ILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELL---- 395
           LAP     SS  P  +L  PP  +    S S     A + PS     L+ +  E++    
Sbjct: 142 LAPHSVQKSSAFPPNLLTSPPSVA-VAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPK 200

Query: 396 ------CLGLADPAPNVPPKESAGNSQWHLLQREQSD-LDFFSPRPGTAACGASDAPLLQ 448
                 C+    P   V P  S  +    L Q   +  L   SP+       +    L+ 
Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSV---LIS 257

Query: 449 PSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLAL 508
           P  P S S + P+ PP    +   S+P  ++          P       P   G H   L
Sbjct: 258 PQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDF-----PISLGSHLAPL 312

Query: 509 GNSALHHLDALDQLLEEAKVTSGLVK-----------------------PTTSPLIPTTT 545
             S+   +  L Q    A ++   VK                       P+ + ++P T 
Sbjct: 313 HQSSFGSVQLLGQTGPSA-LSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATV 371

Query: 546 PARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVTAYDKN 605
            A P++  S   G      ++    GS      L++A+      S+ P+++L +    K+
Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGS------LNVATSF----SLSPTTSLIL----KS 417

Query: 606 GFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKS---MKVKLQPPSGT 662
                +H+        P V  + VS + T PL V +    AA P +   +   + PP  +
Sbjct: 418 SPNATYHY--------PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSS 469

Query: 663 ELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQL 704
              P S I+P +    VM    P +   ++   L   +   L
Sbjct: 470 --GPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPL 509



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 57/241 (23%), Positives = 85/241 (35%), Gaps = 37/241 (15%)

Query: 337  SLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLC 396
            +L  VL  AP P S+  PI+  P +  GP   +SS+ +       S  N           
Sbjct: 1680 ALKEVLV-APAPEST--PIITAPTR-KGPQTKKSSATSPPICPDPSAKNGSKGP------ 1729

Query: 397  LGLADPAPNVP-----PKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSA 451
            L    PAP +P      K + G    H  +   +  +  +  P TAA      P      
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP-----K 1784

Query: 452  PSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNS 511
            P S+S  A   PP   P+ P+ VP          +     L    +P  P          
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE------- 1837

Query: 512  ALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQG 571
                 D L  L+    ++ G+  P  S L+   TP    +P  T       QP++  ++G
Sbjct: 1838 -----DELLPLIPPEPISGGV--PFQSVLVNMPTPKSAGIPVPTPSAK---QPVTKNNKG 1887

Query: 572  S 572
            S
Sbjct: 1888 S 1888



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 99/385 (25%), Positives = 137/385 (35%), Gaps = 66/385 (17%)

Query: 320  CSNQGTLIDLAELDTTNSLSSVLAPAPTPPSS----GIPILPP-PPQASGPPRSRSS-SQ 373
            C+   TL+   E+  +    S L PA TPP +    GI       P AS P    +  S 
Sbjct: 718  CAPLATLVLAPEIPKSVPSPS-LPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSG 776

Query: 374  AEATLGPSSTSNALSWLDEELLCLGLA-DPAPNVPP--KESAG-NSQWHLLQREQSDLDF 429
            A AT   +S+   L++L +    LG++  P    PP  K SAG ++    L    S ++ 
Sbjct: 777  ASAT---ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833

Query: 430  -FSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGV 488
             F P    +  G+ D+P         +++ +P PP       P   P PSA + L   GV
Sbjct: 834  SFLPENSLSFQGSKDSP---------ATTHSPTPPS------PKGAPTPSAVTPLSPKGV 878

Query: 489  APALAPKVEPAVPGHHGLAL-----GNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPT 543
               L PK  P  P    L          A     AL       K       P   P  P+
Sbjct: 879  --TLPPKETP-TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS 935

Query: 544  TTPARPLLPFSTGPG--------SPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSS 595
               A P  P +T P         SP + P    +    PKG   + +    P  +  P +
Sbjct: 936  PKGA-PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS----PKGAPTPPA 990

Query: 596  ALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSMLN----TAPLPVKSIVLQAAVPKS 651
            A P +   K G       A   P G P    V            P P  +    AA P S
Sbjct: 991  ATPPS--PKGG------PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042

Query: 652  MKVKLQPPSGTELSPFSPIQPPAAI 676
             K     P+ T L   +P  P A +
Sbjct: 1043 PK---GSPAATPLPKGAPTTPAATL 1064


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 72/268 (26%), Positives = 103/268 (38%), Gaps = 33/268 (12%)

Query: 339 SSVLAPAPTPPSSGIPI--LPPPPQAS--------GPPRSRSSSQAEATLGPSSTSNALS 388
           +++  PA   P++  P   LPP P+A+        G  R  SSSQ     GP   S+ +S
Sbjct: 663 AAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMS 722

Query: 389 WLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQ 448
              E LL  G   PAP  PP+E+      H ++R         PR       +   P   
Sbjct: 723 RSQEYLLDEG---PAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQT 779

Query: 449 PSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLAL 508
           P+     S QA   P  PAP      P P     L      P ++P+  P  P H G A 
Sbjct: 780 PTKTRPGSPQALGGPHGPAPATAKVKPTP----QLLPPTERP-MSPRSLPQSPTHRGFAY 834

Query: 509 GNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFSTG-PGSPLFQPLS- 566
                     L Q + E +V      P   P +PT  P   L P +   PG P  +  S 
Sbjct: 835 ---------VLPQPV-EGEVGPAAPGPAPPP-VPTAVPTLCLPPEADAEPGRPKKRAHSL 883

Query: 567 --FQSQGSPPKGPELSLASIHVPLESIK 592
             + +  S P+  EL + +   P  +++
Sbjct: 884 NRYAASDSEPERDELLVPAAAGPYATVQ 911



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 53/208 (25%), Positives = 76/208 (36%), Gaps = 19/208 (9%)

Query: 401  DPAPNVPPKESAGNSQWHLLQR----EQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSS 456
            +  P  PP  S  ++    ++R    EQ+      P P  A    +D   L P  P    
Sbjct: 1158 EAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGE 1217

Query: 457  SQAPLPPPF-PAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHH 515
            ++ P  PP  P PV+  + P P    S   T     L     P V   HG     S    
Sbjct: 1218 ARKPAKPPVSPKPVL--TQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSP--K 1273

Query: 516  LDALDQLLEEAKVTSGLVKPTTSPLIPTTTPAR-PLLPFSTGPGSPLFQPLSFQSQG-SP 573
                    +  K  +GL   +  P  P  +PAR P    +  PG+P        S G SP
Sbjct: 1274 PPPPPTAPKPVKAVAGLPSGSAGP-SPAPSPARQPPAALAKPPGTP-------PSLGASP 1325

Query: 574  PKGPELSLASIHVPLESIKPSSALPVTA 601
             K P     ++HVP +  + ++A    A
Sbjct: 1326 AKPPSPGAPALHVPAKPPRAAAAAAAAA 1353



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 45/178 (25%), Positives = 59/178 (33%), Gaps = 18/178 (10%)

Query: 328  DLAELDTTNSLSSVLAPAPTPPSSGIPILPPP-PQASGPPRSRSSSQAEATLGPSSTSNA 386
            DLA L               PP S  P+L  P P+  G P    +S+     GP S    
Sbjct: 1204 DLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTP--TSKKVPLPGPGSP--- 1258

Query: 387  LSWLDEELLCLGLADP-APNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAP 445
                 E     G   P +P  PP  +A      +            P P  +      A 
Sbjct: 1259 -----EVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSA---GPSPAPSPARQPPAA 1310

Query: 446  LLQPSAPSSSSSQAPLPPPFP-APVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPG 502
            L +P     S   +P  PP P AP +      P A ++  +   AP   P  E A PG
Sbjct: 1311 LAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPP--EGASPG 1366



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 36/158 (22%), Positives = 49/158 (31%), Gaps = 49/158 (31%)

Query: 344  PAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPA 403
            P   PP + +  LPP P    PP   +   A+  + P                  L  P 
Sbjct: 1196 PPAEPPPTDLAHLPPLP----PPEGEARKPAKPPVSPKPV---------------LTQPV 1236

Query: 404  PNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPP 463
            P +                        SP P      +   PL  P +P    +    PP
Sbjct: 1237 PKLQG----------------------SPTP-----TSKKVPLPGPGSPEVKRAHGTPPP 1269

Query: 464  PFPAPVVPASVPAP---SAGSSLFSTGVAPALAPKVEP 498
              P P  P + P P    AG    S G +PA +P  +P
Sbjct: 1270 VSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQP 1307



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 13/75 (17%)

Query: 339  SSVLAPAPTPPSSGI-PILPPPPQASG------PPRSRSSSQAEATLGP------SSTSN 385
            +++  P  TPPS G  P  PP P A        PPR+ +++ A A   P      S   +
Sbjct: 1309 AALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDS 1368

Query: 386  ALSWLDEELLCLGLA 400
            A   L+E   CL  A
Sbjct: 1369 ARQKLEETSACLAAA 1383


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 91/357 (25%), Positives = 120/357 (33%), Gaps = 86/357 (24%)

Query: 335 TNSLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEEL 394
           + SLSS   P  +P  SG       P A G PR+ +        G               
Sbjct: 239 SRSLSSSATPLSSPARSG-------PSARGTPRAPAHPSQPKPKG--------------- 276

Query: 395 LCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSS 454
             L    P    PP++ A  +   L     S     +P P  A    S AP   P+ P S
Sbjct: 277 --LQALRPPQVTPPRKDAAPALGPL-----SSSPLATPSPSAAL--QSQAPPTLPATPHS 327

Query: 455 SSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALH 514
           SS    L  P     +P + P+PSA  SL +    PA  P            +LG+  L 
Sbjct: 328 SSLTCQLATP-----LPLAPPSPSAPPSLQTLPSPPATPPSQATT-------SLGSPTLQ 375

Query: 515 HLDALDQLLEEAKVTSGLVKPTTSPLI---PTTTPARPLLPFSTGPGSPLFQPLSFQSQG 571
                          S L  P  SPL    P   PA  L P    P  P   PLS  +  
Sbjct: 376 ------------ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423

Query: 572 SPPKGPELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVVSM 631
           SP     L++  +  P     P  + PV              A   PP  P V       
Sbjct: 424 SPQAPNALAVHLLQAP---FSPPPSPPVQ-------------APFSPPASPPV------- 460

Query: 632 LNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFS---PIQPPAAITQVMLLANP 685
             +A  P ++    AA P  ++V   PP+   +SP +   P  PP      + LA P
Sbjct: 461 SPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 77/274 (28%), Positives = 99/274 (36%), Gaps = 38/274 (13%)

Query: 335 TNSLSSVLA-PAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEE 393
           ++SL+  LA P P  P S  P  PP  Q    P +   SQA  +LG  +     S+L   
Sbjct: 327 SSSLTCQLATPLPLAPPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 384

Query: 394 LLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQP--SA 451
            L   LA P P  PP  +    Q          L   +  P   A  A    LLQ   S 
Sbjct: 385 PLS-PLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFSP 442

Query: 452 PSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLF--------STGVAPALAPKVEPAVPGH 503
           P S   QAP  PP   PV P++ P   A  SL         S   +P ++P   P     
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502

Query: 504 HGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTS--PLIPTTTPAR-PLLPFSTGPGSP 560
             LA           L       +    L  P     P  P + P + P  P ++ P SP
Sbjct: 503 PPLA--------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554

Query: 561 LFQPLSFQSQGSPPKGPELSLASIHVPLESIKPS 594
           L  P        PP+ P +  A    PL  + PS
Sbjct: 555 LATP--------PPQAPPVLAA----PLLQVPPS 576



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 79/293 (26%), Positives = 99/293 (33%), Gaps = 65/293 (22%)

Query: 339 SSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLG 398
           S  ++P+ TPPS   P L  PP    P     S  A   + PS+T    +        L 
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPP-----SPPASPPMSPSATPPPQAPPPLAAPPLQ 511

Query: 399 LADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASD-------------AP 445
           LA P P  PP  +    Q   L    +     +P   +A+   S              AP
Sbjct: 512 LAKPPPQAPPALATPPLQ--ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 569

Query: 446 LLQ--PSAPSSSSSQAPLPPPFPAP------------VVPASVPAPSAGSSLFSTGVAPA 491
           LLQ  PS P+S + QAP  PP P P            + P   P PS   S   +G    
Sbjct: 570 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---- 625

Query: 492 LAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPA---- 547
                 P + GH   A   S    L   D   E     S    P     +    PA    
Sbjct: 626 ------PDLAGHSSSA--TSTPEELRGYDSGPEGGAAAS----PPPDAELAACHPAAWSR 673

Query: 548 --RPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALP 598
              P L F   PG+PL  P        P  GP  S   +    E+  P SA P
Sbjct: 674 GPAPPLAFRGAPGAPLPWP--------PATGPG-SADGLCTIYETEGPESATP 717



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 93/376 (24%), Positives = 126/376 (33%), Gaps = 66/376 (17%)

Query: 334 TTNSLSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSST-SNALSWLDE 392
           T ++ +S   PA  PP+SG     PP + + P    S  +A  T  P       L    E
Sbjct: 80  TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139

Query: 393 ELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGT---AACGASDAPLLQP 449
           E +  G A  A    PK SA ++         +  D   P PGT   A    S A   + 
Sbjct: 140 ETVARGKATEA----PKRSALSA--------GARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 450 SAPSSSSSQAPLPP-PFPAPVV------------PASVPAPSAGSSL---FSTGVAPALA 493
             P  + S  P PP   P   V            PA+   PSAG  L    S  ++ +  
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247

Query: 494 PKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPF 553
           P   PA  G        +  H          + K    L  P  +P  P    A  L P 
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQ------PKPKGLQALRPPQVTP--PRKDAAPALGPL 299

Query: 554 STGPGSPLFQPLSFQSQGSP--PKGPELS--LASIHVPLESIKPSSALPVTAYDKNGFRI 609
           S+ P +      + QSQ  P  P  P  S     +  PL    PS + P +         
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ------- 352

Query: 610 LFHFAKECPPGRP----------DVLVVVVSMLNTAPL-PVKSIVLQAAVPKSMKVKLQP 658
                   PP  P            L    S L + PL P+ +   QA    ++     P
Sbjct: 353 ----TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 408

Query: 659 PSGTELSPFSPIQPPA 674
           PS     P SP+  P+
Sbjct: 409 PSPPASPPLSPLATPS 424



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 55/205 (26%), Positives = 70/205 (34%), Gaps = 34/205 (16%)

Query: 338 LSSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCL 397
           L+  LAP P PP    P   P    SGP  +  SS A      +ST   L   D      
Sbjct: 603 LTLALAPGPPPP----PSRSPSSTLSGPDLAGHSSSA------TSTPEELRGYDSGPEGG 652

Query: 398 GLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSS 457
             A P P+     +   + W              P P  A  GA  APL  P A    S+
Sbjct: 653 AAASPPPDA-ELAACHPAAWSR-----------GPAPPLAFRGAPGAPLPWPPATGPGSA 700

Query: 458 QA----------PLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGL- 506
                           P P  + P   P  S G +    G A A +   + A  G   L 
Sbjct: 701 DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG-AGASSRSPKQARLGELPLG 759

Query: 507 ALGNSALHHLDALDQLLEEAKVTSG 531
           AL  S + HL +   LL  A+  +G
Sbjct: 760 ALQASVVQHLLSRTLLLAAAEGAAG 784


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 71/289 (24%), Positives = 105/289 (36%), Gaps = 27/289 (9%)

Query: 330  AELDTTNSLSSVLAPAPTP--PSSGIPILPPP-----PQASGPPRSRSSSQAEATLGPSS 382
            A + T    +S  A  PTP  P+S    +PPP     P A+ P     +S A A   P  
Sbjct: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1064

Query: 383  TSNALSWLD--EELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACG 440
             ++  + +   EE      A P P  P   +A          E +      P P   A  
Sbjct: 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT----PEEPTSPAAAVPTPEEPASP 1120

Query: 441  ASDAPLLQPSAPSSSSSQAPLP--PPFPAPVVP---------ASVPAPSAGSSLFSTGVA 489
            A+  P   P  P+S ++  P P  P FPAP VP          +VP P   +S  +    
Sbjct: 1121 AAAVPT--PEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT 1178

Query: 490  PALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPLIPTTTPARP 549
            PA +      V          +++    A+   LEE    +  V  +  P       + P
Sbjct: 1179 PAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP 1238

Query: 550  LLPFSTGPGSP-LFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSAL 597
              P S     P L +P S  +    P+      AS+  P E   P++A+
Sbjct: 1239 EEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAV 1287



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 45/179 (25%), Positives = 65/179 (36%), Gaps = 22/179 (12%)

Query: 333  DTTNSLSSVLAPAP--------TPPSSGIPILPPPPQ----ASGPPRSRSSSQAEATLGP 380
            + T+  +SV  PA         T P++ +P    P       S P    S + A  TL  
Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE 1253

Query: 381  SSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACG 440
             ++S A     EEL     + P P  P   +A  S       E +      P P  AA  
Sbjct: 1254 PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSN----LEEPASPAAAVPTPEVAAIP 1309

Query: 441  ASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPA 499
            A+  P   P  P+  +  A +PP     V P  VP     +   S  ++    P +E A
Sbjct: 1310 AASVP--TPEVPAIPA--AAVPP--MEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEA 1362



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 53/251 (21%), Positives = 90/251 (35%), Gaps = 23/251 (9%)

Query: 353  IPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESA 412
            IP+L  P + +  P  + +  A        TS A     E    +    P P+     ++
Sbjct: 828  IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887

Query: 413  GNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFP-APVVP 471
                  ++  E+ D+         +A   +  P +  S P  +++ A +  P   AP V 
Sbjct: 888  ------IVSLEEEDVT----AAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVA 937

Query: 472  ASVPAPS----AGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAK 527
            A++        AG S     +A  +    E   P   G     + +H  +  D     A 
Sbjct: 938  AAITQEGMSAVAGFSPEWAALAITVPITEEDGTP--EGPVTPATTVHAPEEPDT----AA 991

Query: 528  VTSGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVP 587
            V     +   SP     TP  P  P +  P     +P S  +   PP+ P    A++  P
Sbjct: 992  VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE--EPTSPAAAVPPPEEPTSPAAAVPTP 1049

Query: 588  LESIKPSSALP 598
             E   P++A+P
Sbjct: 1050 EEPTSPAAAVP 1060


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 81/320 (25%), Positives = 115/320 (35%), Gaps = 70/320 (21%)

Query: 334 TTNSLSSVLAPAPTPP----SSGIP-ILPPPPQASGPPRSRSSSQAEATLGPSSTSNALS 388
           TT +LS    P+  PP     SG P +LP P   S PP +        ++ P++ + A  
Sbjct: 356 TTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPP 415

Query: 389 WLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQ 448
            L  E      A  AP+  PK+S       L   + +     SP    A   +S  P+ +
Sbjct: 416 TLQAETATKPQATSAPSPAPKQS------FLFGTQNT-----SPSSPAAPAASSAPPMFK 464

Query: 449 P--SAPSSSSSQAPLPP----------------------PFPAPVV-----PASVPAPSA 479
           P  +AP  S  + P PP                      P   PV      PASVP P  
Sbjct: 465 PIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLP-- 522

Query: 480 GSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEA----------KVT 529
            +  F     PA AP      P   GLA   SA+  + +     + A           V+
Sbjct: 523 -APFFKQTTTPATAPTT--TAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVS 579

Query: 530 SGLVKPTTSPLIPTTTPARPLLPFSTGPGSPLFQPL--SFQSQGSPPKGPELSLA----- 582
           S  V  TTS     T  ++P L  +    +  F P   S    G PP  P  +       
Sbjct: 580 SSSVSTTTS---TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQ 636

Query: 583 SIHVPLESIKPSSALPVTAY 602
           S+H  + +   SSA   + +
Sbjct: 637 SLHTAVPTATSSSAADFSGF 656



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 62/265 (23%), Positives = 92/265 (34%), Gaps = 53/265 (20%)

Query: 339 SSVLAPAPTPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLG 398
           +S+LAP+  P    +  +  PP     P S  ++  EA L P  T + L         LG
Sbjct: 322 TSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEA-LSPPKTPSLLP-------PLG 373

Query: 399 LADPA-PNVPPKESAGNSQWHLLQREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSS 457
           L+    P + P  S                  F  +P T   G   AP + P+  + +  
Sbjct: 374 LSQSGPPGLLPSPS------------------FDSKPPTTLLGLIPAPSMVPATDTKAPP 415

Query: 458 QAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLD 517
                         A  PAP       +   +P+      PA P          A     
Sbjct: 416 TLQAETATKPQATSAPSPAPKQSFLFGTQNTSPS-----SPAAP----------AASSAP 460

Query: 518 ALDQLLEEAKVTSGLVKPT-TSPLIPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKG 576
            + + +  A   S    PT   P +  T P+   LP +T   +P FQP+ F S G P   
Sbjct: 461 PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPV-FSSMGPP--- 516

Query: 577 PELSLASIHVPLESIKPSSALPVTA 601
                AS+ +P    K ++  P TA
Sbjct: 517 -----ASVPLPAPFFKQTTT-PATA 535



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 54/222 (24%), Positives = 76/222 (34%), Gaps = 29/222 (13%)

Query: 347 TPPSSGIPILPPPPQASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNV 406
           TP    I     PP         + SQ+  T  P++TS++ +        L  + PA + 
Sbjct: 610 TPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSS 669

Query: 407 PPKESAGNSQWHLLQ-----REQSDLDFFSPRPGTAACGASDA-------PLLQPSAPSS 454
            P  +  N+             +S L  +       A GA++        P L PS  SS
Sbjct: 670 QPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSS 729

Query: 455 ---SSSQAPLPPPFPAP-----VVPASVPAP---------SAGSSLFSTGVAPALAPKVE 497
               +S AP   P PAP     VVPA VP P          +   L +T  A       +
Sbjct: 730 FTFGNSAAPAAAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQ 789

Query: 498 PAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSP 539
           PA  G   +  G +      A  Q       +S     T SP
Sbjct: 790 PAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPSP 831


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,799,594
Number of Sequences: 37866
Number of extensions: 1985937
Number of successful extensions: 22300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 1092
Number of HSP's that attempted gapping in prelim test: 13418
Number of HSP's gapped (non-prelim): 6758
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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