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Search of human proteins with 20270387
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20270387 hypothetical protein LOC159091 [Homo sapiens]
(152 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20270387 hypothetical protein LOC159091 [Homo sapiens] 300 2e-82
gi|49472830 hypothetical protein LOC116224 [Homo sapiens] 134 2e-32
gi|40255094 hypothetical protein LOC159090 [Homo sapiens] 92 2e-19
gi|5453918 solute carrier family 25 (mitochondrial carrier; pero... 30 0.61
gi|226246554 hypothetical protein LOC643677 [Homo sapiens] 29 1.8
gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap... 29 1.8
gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap... 29 1.8
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap... 29 1.8
gi|13129148 apolipoprotein O [Homo sapiens] 29 1.8
gi|110611228 utrophin [Homo sapiens] 29 1.8
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 28 2.3
gi|6005747 ring finger protein 2 [Homo sapiens] 27 5.1
gi|148746206 MAGE-like protein 2 [Homo sapiens] 27 5.1
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 27 6.7
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 27 8.8
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 27 8.8
gi|26051271 voltage-gated potassium channel, subfamily H, member... 27 8.8
gi|4557729 voltage-gated potassium channel, subfamily H, member ... 27 8.8
gi|153792284 pote protein [Homo sapiens] 27 8.8
gi|10092691 tight junction protein 3 [Homo sapiens] 27 8.8
gi|31982906 cingulin-like 1 [Homo sapiens] 27 8.8
gi|207444687 solute carrier family 41, member 2 [Homo sapiens] 27 8.8
>gi|20270387 hypothetical protein LOC159091 [Homo sapiens]
Length = 152
Score = 300 bits (769), Expect = 2e-82
Identities = 152/152 (100%), Positives = 152/152 (100%)
Query: 1 MAQEKMKLGFKSLPSSTTADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNR 60
MAQEKMKLGFKSLPSSTTADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNR
Sbjct: 1 MAQEKMKLGFKSLPSSTTADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNR 60
Query: 61 RSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDNGL 120
RSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDNGL
Sbjct: 61 RSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDNGL 120
Query: 121 QKSSSLKCIDLTPVSSMASSIKKTGKSTSSYF 152
QKSSSLKCIDLTPVSSMASSIKKTGKSTSSYF
Sbjct: 121 QKSSSLKCIDLTPVSSMASSIKKTGKSTSSYF 152
>gi|49472830 hypothetical protein LOC116224 [Homo sapiens]
Length = 287
Score = 134 bits (338), Expect = 2e-32
Identities = 81/159 (50%), Positives = 97/159 (61%), Gaps = 10/159 (6%)
Query: 1 MAQEKMKLGFKSLPSST---------TADGNILRRVNSAPLINGLGFNSQVLQADMLRIR 51
MAQEKM+L + LP T + G LRR NSAPLI+GL S V QA+ R
Sbjct: 1 MAQEKMELDLE-LPPGTGGSPAEGGGSGGGGGLRRSNSAPLIHGLSDTSPVFQAEAPSAR 59
Query: 52 TNRTTFRNRRSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHSWEE 111
N TTF +R LLLP P SRLHQIKQEE MDLINRET+ E ++Q+ +QISHSWEE
Sbjct: 60 RNSTTFPSRHGLLLPASPVRMHSSRLHQIKQEEGMDLINRETVHEREVQTAMQISHSWEE 119
Query: 112 GLKLNDNGLQKSSSLKCIDLTPVSSMASSIKKTGKSTSS 150
L+DN ++KS+S K ID PVS S + GK S
Sbjct: 120 SFSLSDNDVEKSASPKRIDFIPVSPAPSPTRGIGKQCFS 158
>gi|40255094 hypothetical protein LOC159090 [Homo sapiens]
Length = 248
Score = 91.7 bits (226), Expect = 2e-19
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 26/149 (17%)
Query: 1 MAQEKMKLGFKSLPSSTTADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNR 60
MAQEKM+L + T+ G LRR +SAPLI+GL SQV Q LR R N TT +R
Sbjct: 1 MAQEKMELDLEP----DTSYGGTLRRSSSAPLIHGLSDLSQVFQPYTLRTRRNSTTIMSR 56
Query: 61 RSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDNGL 120
SL EE +D++NRET E ++Q+ +QIS SW+E L L+D+
Sbjct: 57 HSL-------------------EEGLDMVNRETAHEREMQTAMQISQSWDESLSLSDSDF 97
Query: 121 QKSSSL---KCIDLTPVSSMASSIKKTGK 146
K L K ID TPVS S + GK
Sbjct: 98 DKPEKLYSPKRIDFTPVSPAPSPTRGFGK 126
>gi|5453918 solute carrier family 25 (mitochondrial carrier;
peroxisomal membrane protein, 34kDa), member 17 [Homo
sapiens]
Length = 307
Score = 30.4 bits (67), Expect = 0.61
Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Query: 49 RIRTNRTTFRNRRSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHS 108
R++ FRN + P + G I HQI ++E + + T L I
Sbjct: 128 RLKLQGAKFRNED---IVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFM 184
Query: 109 WEEGLKLNDNGLQKSSSLKCIDLTPVSSMASSIKKT 144
+ EGLK L+K L +D+ + ++A +I T
Sbjct: 185 FYEGLK--RQLLKKRMKLSSLDVFIIGAVAKAIATT 218
>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
Length = 7081
Score = 28.9 bits (63), Expect = 1.8
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 23/144 (15%)
Query: 18 TADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNRRSLLLPPPPFHGSISRL 77
T DG I V S G N +V DM RI++ + R+S S+S +
Sbjct: 3642 TIDGVISSNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKS----------SLSHI 3691
Query: 78 HQIKQ-EEAMDLINRE-TMSEWKLQSEIQISH--------SWEEGLKLNDNGLQKSSSLK 127
IK+ +D+I +E M E K +S +++++ S G KS +LK
Sbjct: 3692 LSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLK 3751
Query: 128 -CIDLTPVSSMASSIKKTGKSTSS 150
C L P+ ASS + S S
Sbjct: 3752 GC--LPPLKLQASSNARRVSSAES 3773
>gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
Length = 6929
Score = 28.9 bits (63), Expect = 1.8
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 23/144 (15%)
Query: 18 TADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNRRSLLLPPPPFHGSISRL 77
T DG I V S G N +V DM RI++ + R+S S+S +
Sbjct: 3571 TIDGVISSNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKS----------SLSHI 3620
Query: 78 HQIKQ-EEAMDLINRE-TMSEWKLQSEIQISH--------SWEEGLKLNDNGLQKSSSLK 127
IK+ +D+I +E M E K +S +++++ S G KS +LK
Sbjct: 3621 LSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLK 3680
Query: 128 -CIDLTPVSSMASSIKKTGKSTSS 150
C L P+ ASS + S S
Sbjct: 3681 GC--LPPLKLQASSNARRVSSAES 3702
>gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
Length = 6929
Score = 28.9 bits (63), Expect = 1.8
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 23/144 (15%)
Query: 18 TADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNRRSLLLPPPPFHGSISRL 77
T DG I V S G N +V DM RI++ + R+S S+S +
Sbjct: 3571 TIDGVISSNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKS----------SLSHI 3620
Query: 78 HQIKQ-EEAMDLINRE-TMSEWKLQSEIQISH--------SWEEGLKLNDNGLQKSSSLK 127
IK+ +D+I +E M E K +S +++++ S G KS +LK
Sbjct: 3621 LSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLK 3680
Query: 128 -CIDLTPVSSMASSIKKTGKSTSS 150
C L P+ ASS + S S
Sbjct: 3681 GC--LPPLKLQASSNARRVSSAES 3702
>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
Length = 6929
Score = 28.9 bits (63), Expect = 1.8
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 23/144 (15%)
Query: 18 TADGNILRRVNSAPLINGLGFNSQVLQADMLRIRTNRTTFRNRRSLLLPPPPFHGSISRL 77
T DG I V S G N +V DM RI++ + R+S S+S +
Sbjct: 3571 TIDGVISSNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKS----------SLSHI 3620
Query: 78 HQIKQ-EEAMDLINRE-TMSEWKLQSEIQISH--------SWEEGLKLNDNGLQKSSSLK 127
IK+ +D+I +E M E K +S +++++ S G KS +LK
Sbjct: 3621 LSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLK 3680
Query: 128 -CIDLTPVSSMASSIKKTGKSTSS 150
C L P+ ASS + S S
Sbjct: 3681 GC--LPPLKLQASSNARRVSSAES 3702
>gi|13129148 apolipoprotein O [Homo sapiens]
Length = 198
Score = 28.9 bits (63), Expect = 1.8
Identities = 15/55 (27%), Positives = 26/55 (47%)
Query: 64 LLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDN 118
L+ PP F G + L+ +Q ++ E + +W L+ I I W+E + N
Sbjct: 136 LVYPPGFMGLAASLYYPQQAIVFAQVSGERLYDWGLRGYIVIEDLWKENFQKPGN 190
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 28.9 bits (63), Expect = 1.8
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 8/95 (8%)
Query: 40 SQVLQADML---RIRTNRTTFRNRRSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSE 96
SQ+ Q D+L R+R T ++++ L PPPP I I+ ++ D I+ E ++
Sbjct: 645 SQIPQKDLLETVRVREQAITKKSKQELPPPPPPKKRQIH--VDIEAKKKFDAISAELLN- 701
Query: 97 WKLQSEIQI-SHSWEEGLKLNDNGLQKSSSLKCID 130
W L+ + I + +E +K+ D K LK ++
Sbjct: 702 WILKWKTAIQTTEIKEYMKMQDTSEMK-KKLKALE 735
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 28.5 bits (62), Expect = 2.3
Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 11/109 (10%)
Query: 49 RIRTNRTTFR--NRRSLLLPP---PPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEI 103
R+R T ++ NR+ L P P G + ++ MDLIN+E W + +
Sbjct: 1397 RLRRLVTVYQRCNRKELCRPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQA 1456
Query: 104 QISHSWEEGLKLNDNGLQKSSSLKCIDLTPVSSMASSIKKTGKSTSSYF 152
+ ++ G+ K D T ++ KK+ +S YF
Sbjct: 1457 DFYRT------VSSFGVVYDQEKKTFDWTQFRIISRLDKKSDESLEQYF 1499
>gi|6005747 ring finger protein 2 [Homo sapiens]
Length = 336
Score = 27.3 bits (59), Expect = 5.1
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 15/78 (19%)
Query: 52 TNRTTFRNRRSLLLPPPPFHGSISRLH------QIKQEEAMDLINRETMSEWKLQSEIQI 105
T R ++RSL P P F IS+++ + QE + IN+ + +
Sbjct: 89 TCRKKLVSKRSLR-PDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQ-------AL 140
Query: 106 SHSWEEGLKLND-NGLQK 122
SHS EEGLK+ N LQ+
Sbjct: 141 SHSIEEGLKIQAMNRLQR 158
>gi|148746206 MAGE-like protein 2 [Homo sapiens]
Length = 646
Score = 27.3 bits (59), Expect = 5.1
Identities = 9/17 (52%), Positives = 14/17 (82%)
Query: 94 MSEWKLQSEIQISHSWE 110
+S+W++QS IQ+S WE
Sbjct: 316 LSDWEVQSPIQVSGDWE 332
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 26.9 bits (58), Expect = 6.7
Identities = 19/84 (22%), Positives = 39/84 (46%)
Query: 60 RRSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDNG 119
R +LLL P + K EE+ ++ + E L +E+Q E+ K +
Sbjct: 417 RENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTR 476
Query: 120 LQKSSSLKCIDLTPVSSMASSIKK 143
L+K++ ++T S+ S++++
Sbjct: 477 LEKTAKELEEEITLRKSVESALRQ 500
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 26.6 bits (57), Expect = 8.8
Identities = 16/67 (23%), Positives = 35/67 (52%)
Query: 84 EAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDNGLQKSSSLKCIDLTPVSSMASSIKK 143
+A++L + + +LQ ++ +WE+ +K D L++ + + +L P+ + KK
Sbjct: 6 KAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGNFRKKK 65
Query: 144 TGKSTSS 150
GK+ S
Sbjct: 66 KGKAKES 72
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 26.6 bits (57), Expect = 8.8
Identities = 16/67 (23%), Positives = 35/67 (52%)
Query: 84 EAMDLINRETMSEWKLQSEIQISHSWEEGLKLNDNGLQKSSSLKCIDLTPVSSMASSIKK 143
+A++L + + +LQ ++ +WE+ +K D L++ + + +L P+ + KK
Sbjct: 6 KAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGNFRKKK 65
Query: 144 TGKSTSS 150
GK+ S
Sbjct: 66 KGKAKES 72
>gi|26051271 voltage-gated potassium channel, subfamily H, member 2
isoform b [Homo sapiens]
Length = 888
Score = 26.6 bits (57), Expect = 8.8
Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 5/41 (12%)
Query: 61 RSLLLPPPPFHGSISRLHQIK-----QEEAMDLINRETMSE 96
R+ +LPPPP H S +H ++ DL+ T+S+
Sbjct: 292 RAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISK 332
>gi|4557729 voltage-gated potassium channel, subfamily H, member 2
isoform a [Homo sapiens]
Length = 1159
Score = 26.6 bits (57), Expect = 8.8
Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 5/41 (12%)
Query: 61 RSLLLPPPPFHGSISRLHQIK-----QEEAMDLINRETMSE 96
R+ +LPPPP H S +H ++ DL+ T+S+
Sbjct: 292 RAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISK 332
>gi|153792284 pote protein [Homo sapiens]
Length = 584
Score = 26.6 bits (57), Expect = 8.8
Identities = 15/53 (28%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 80 IKQEEAMDLINRET-MSEWKLQSEIQISHSWEEGLKLNDNGLQKSSSLKCIDL 131
I Q+E + ++ ++E K+ SE+ +SH EE L ++ LQ+ ++ ++L
Sbjct: 488 ISQDEILTNKQKQIEVAEQKMNSELSLSHKKEEDLLRENSVLQEEIAMLRLEL 540
>gi|10092691 tight junction protein 3 [Homo sapiens]
Length = 952
Score = 26.6 bits (57), Expect = 8.8
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 88 LINRETMSEW--KLQSEIQISHSWEEGLKLNDNGLQKSSSLKCIDLTPVSSMASSIKKT 144
L+ R E+ KL S+I I H + GL GLQ+ + + + VSS S+ T
Sbjct: 216 LVKRRDSEEFGVKLGSQIFIKHITDSGLAARHRGLQEGDLI--LQINGVSSQNLSLNDT 272
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 26.6 bits (57), Expect = 8.8
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 10/86 (11%)
Query: 52 TNRTTFRNRRSLLLPPPPFHGSIS--------RLHQIKQ--EEAMDLINRETMSEWKLQS 101
+NR R + L++ H S++ RL +K+ EEA + I+R S+ KLQ
Sbjct: 1175 SNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQR 1234
Query: 102 EIQISHSWEEGLKLNDNGLQKSSSLK 127
E++ E L+ N ++K LK
Sbjct: 1235 ELEEQMDMNEHLQGQLNSMKKDLRLK 1260
>gi|207444687 solute carrier family 41, member 2 [Homo sapiens]
Length = 573
Score = 26.6 bits (57), Expect = 8.8
Identities = 12/33 (36%), Positives = 20/33 (60%)
Query: 16 STTADGNILRRVNSAPLINGLGFNSQVLQADML 48
+T +D N++ V P+ING+G N +QA +
Sbjct: 400 TTVSDPNLVGIVVYTPVINGIGGNLVAIQASRI 432
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,597,769
Number of Sequences: 37866
Number of extensions: 209448
Number of successful extensions: 477
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 459
Number of HSP's gapped (non-prelim): 29
length of query: 152
length of database: 18,247,518
effective HSP length: 93
effective length of query: 59
effective length of database: 14,725,980
effective search space: 868832820
effective search space used: 868832820
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.