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Search of human proteins with 20270345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20270345 spermatogenesis associated 17 [Homo sapiens]
(361 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20270345 spermatogenesis associated 17 [Homo sapiens] 740 0.0
gi|215982794 myosin VA isoform 2 [Homo sapiens] 54 2e-07
gi|215982791 myosin VA isoform 1 [Homo sapiens] 54 2e-07
gi|126116596 asp (abnormal spindle)-like, microcephaly associate... 45 8e-05
gi|154354979 myosin X [Homo sapiens] 44 2e-04
gi|156119615 myosin IXA [Homo sapiens] 44 3e-04
gi|44662817 IQ motif containing F2 [Homo sapiens] 43 4e-04
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 42 9e-04
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 42 9e-04
gi|222831628 IQ motif containing F5 [Homo sapiens] 42 0.001
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom... 40 0.003
gi|229577354 IQ motif containing F1 [Homo sapiens] 39 0.006
gi|122937512 myosin VIIB [Homo sapiens] 39 0.006
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 39 0.009
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 39 0.009
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 39 0.009
gi|194328685 myosin IB isoform 1 [Homo sapiens] 38 0.012
gi|240120050 myosin IB isoform 1 [Homo sapiens] 38 0.012
gi|153945715 myosin VC [Homo sapiens] 38 0.012
gi|28269672 serologically defined colon cancer antigen 8 [Homo s... 37 0.021
gi|224451032 KIAA1683 isoform a [Homo sapiens] 37 0.027
gi|224451036 KIAA1683 isoform c [Homo sapiens] 37 0.027
gi|54606862 KIAA1683 isoform b [Homo sapiens] 37 0.027
gi|44889481 myosin IB isoform 2 [Homo sapiens] 36 0.047
gi|124494247 myosin IC isoform b [Homo sapiens] 36 0.061
gi|124494238 myosin IC isoform a [Homo sapiens] 36 0.061
gi|124494240 myosin IC isoform c [Homo sapiens] 36 0.061
gi|224591408 SH2 domain containing 4B isoform 2 [Homo sapiens] 35 0.080
gi|224591406 SH2 domain containing 4B isoform 1 [Homo sapiens] 35 0.080
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 35 0.10
>gi|20270345 spermatogenesis associated 17 [Homo sapiens]
Length = 361
Score = 740 bits (1911), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 1 MATLARLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVT 60
MATLARLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVT
Sbjct: 1 MATLARLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVT 60
Query: 61 IIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEY 120
IIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEY
Sbjct: 61 IIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEY 120
Query: 121 LKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNS 180
LKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNS
Sbjct: 121 LKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNS 180
Query: 181 PFRKEPDPWELQLQKAKPLTHRRPKVKQKDSTSLTDWLACTSARSFPRSEILPPINRKQC 240
PFRKEPDPWELQLQKAKPLTHRRPKVKQKDSTSLTDWLACTSARSFPRSEILPPINRKQC
Sbjct: 181 PFRKEPDPWELQLQKAKPLTHRRPKVKQKDSTSLTDWLACTSARSFPRSEILPPINRKQC 240
Query: 241 QGPFRDITEVLEQRYRPLEPTLRVAEPIDELKLAREELRREEWLQNVNDNMFLPFSSYHK 300
QGPFRDITEVLEQRYRPLEPTLRVAEPIDELKLAREELRREEWLQNVNDNMFLPFSSYHK
Sbjct: 241 QGPFRDITEVLEQRYRPLEPTLRVAEPIDELKLAREELRREEWLQNVNDNMFLPFSSYHK 300
Query: 301 NEKYIPSMHLSSKYGPISYKEQFRSENPKKWICDKDFQTVLPSFELFSKYGKLYSKAGQI 360
NEKYIPSMHLSSKYGPISYKEQFRSENPKKWICDKDFQTVLPSFELFSKYGKLYSKAGQI
Sbjct: 301 NEKYIPSMHLSSKYGPISYKEQFRSENPKKWICDKDFQTVLPSFELFSKYGKLYSKAGQI 360
Query: 361 V 361
V
Sbjct: 361 V 361
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 54.3 bits (129), Expect = 2e-07
Identities = 65/234 (27%), Positives = 107/234 (45%), Gaps = 36/234 (15%)
Query: 1 MATLARLQA---RSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNR 57
+A L +L+A R++ + Q R ++ + AA+ +Q + RG Q R Y + L R
Sbjct: 755 VAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRR 814
Query: 58 I--VTIIQKWWRSFLGRKQYQL----TVQVAYYT---MMMNLYNAM-----AVRIQRRWR 103
TIIQK+WR ++ R++Y++ T+ + Y + N Y + AV IQ+R R
Sbjct: 815 TKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVR 874
Query: 104 GYRVRKYLFNYYYLKEYLKVVSETNDAIR--KALEEFAEMKER--------EEKKANLER 153
G+ R + + YL+ A R K L+ A ER E K L+R
Sbjct: 875 GWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQR 934
Query: 154 --EEKKRDYQARKMHYLLSTKQIPGIYNS---PFRKEPDPWELQLQKAKPLTHR 202
+E+ +DY+ + + GIYNS R + + +L ++AK T R
Sbjct: 935 KVDEQNKDYKC----LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGR 984
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 54.3 bits (129), Expect = 2e-07
Identities = 65/234 (27%), Positives = 107/234 (45%), Gaps = 36/234 (15%)
Query: 1 MATLARLQA---RSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNR 57
+A L +L+A R++ + Q R ++ + AA+ +Q + RG Q R Y + L R
Sbjct: 755 VAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRR 814
Query: 58 I--VTIIQKWWRSFLGRKQYQL----TVQVAYYT---MMMNLYNAM-----AVRIQRRWR 103
TIIQK+WR ++ R++Y++ T+ + Y + N Y + AV IQ+R R
Sbjct: 815 TKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVR 874
Query: 104 GYRVRKYLFNYYYLKEYLKVVSETNDAIR--KALEEFAEMKER--------EEKKANLER 153
G+ R + + YL+ A R K L+ A ER E K L+R
Sbjct: 875 GWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQR 934
Query: 154 --EEKKRDYQARKMHYLLSTKQIPGIYNS---PFRKEPDPWELQLQKAKPLTHR 202
+E+ +DY+ + + GIYNS R + + +L ++AK T R
Sbjct: 935 KVDEQNKDYKC----LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGR 984
>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
[Homo sapiens]
Length = 3477
Score = 45.4 bits (106), Expect = 8e-05
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 18/120 (15%)
Query: 10 RSSTVGNQYYFRNSVVDPFRKKE----NDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKW 65
R+S + Q ++R + + KE A+KIQS +RG +VR +I+H++R T I+
Sbjct: 2067 RASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAM 2126
Query: 66 WRSFLGRKQYQ------LTVQV---AYYTMMMNLYNAMAVR-----IQRRWRGYRVRKYL 111
++ R Y + +QV AYY M + + +Q +RG RVR+ L
Sbjct: 2127 FKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTL 2186
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 18/93 (19%)
Query: 31 KENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNL 90
K A V +QS +RG +VR I+ N+ IQ +R++ +K+Y
Sbjct: 2019 KTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYA-------------T 2065
Query: 91 YNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKV 123
Y A A+ IQR +RG ++ + KEYL +
Sbjct: 2066 YRASAIIIQRWYRGIKITNHQH-----KEYLNL 2093
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 14/93 (15%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQ-----LTVQVAYYTMMMN 89
A + IQS++RG +VR I++++R T+IQ ++R + Y+ + V YY + +
Sbjct: 2668 AVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVR 2727
Query: 90 L----YNAMAVR-----IQRRWRGYRVRKYLFN 113
+ N +AV+ IQ +RG +VR+ L N
Sbjct: 2728 VKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKN 2760
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 14/116 (12%)
Query: 7 LQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWW 66
+Q R S + Q + R +V + + A + +QS+FR + R Y + + + +IQ ++
Sbjct: 1726 MQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYY 1785
Query: 67 ----------RSFLGRKQYQLTVQVAY----YTMMMNLYNAMAVRIQRRWRGYRVR 108
++FL K+ +Q AY ++ + A++IQ +RGY R
Sbjct: 1786 HAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKR 1841
Score = 39.7 bits (91), Expect = 0.004
Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 11/106 (10%)
Query: 7 LQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWW 66
LQ + + Q +R V K+++ AA+KIQS FRG R + + + + IQ+W+
Sbjct: 1799 LQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWY 1858
Query: 67 RSFLGRKQYQLTVQVAYYTMMMNL-YNAMAVRIQRRWRGYRVRKYL 111
R++ + + T L A + +Q +RG++VRK +
Sbjct: 1859 RAY----------KTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQI 1894
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/109 (23%), Positives = 50/109 (45%), Gaps = 14/109 (12%)
Query: 17 QYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRK-QY 75
Q++ + +V ++ AA+ +Q +FR Q R + ++Q +R+FL K Q
Sbjct: 2844 QFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQR 2903
Query: 76 QLTVQVAYYTMMMNLYNA-------------MAVRIQRRWRGYRVRKYL 111
Q+ +Q+ +++ + ++IQ WR YR +KYL
Sbjct: 2904 QVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYL 2952
Score = 39.3 bits (90), Expect = 0.006
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 9/118 (7%)
Query: 7 LQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWW 66
L+ +++ V Q +R V K N AAV IQS +R + + IIQ+W+
Sbjct: 2018 LKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWY 2077
Query: 67 RSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVV 124
R + + + +NL A++IQ +RG RVR+++ + + ++K +
Sbjct: 2078 RG--------IKITNHQHKEYLNL-KKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAM 2126
Score = 37.7 bits (86), Expect = 0.016
Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 11/106 (10%)
Query: 7 LQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWW 66
L+ +++ + Q +R V ++E+ AA+KIQS FR + + R +IQ+ +
Sbjct: 1872 LKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNF 1931
Query: 67 RSF-LGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYL 111
R++ GRKQ +++ + ++ +Q W+G +R+ L
Sbjct: 1932 RAWTAGRKQCMEYIELRHAVLV----------LQSMWKGKTLRRQL 1967
Score = 37.7 bits (86), Expect = 0.016
Identities = 39/174 (22%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 6 RLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKW 65
+LQ + + +Y F+ E +Q+ F+ ++ I+ ++ IIQK
Sbjct: 2575 KLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKH 2634
Query: 66 WRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVR------IQRRWRGYRVRKYLFNY----- 114
++F RK Y L ++ ++ AVR IQ +RG++VRK + N
Sbjct: 2635 CKAFKIRKHY-LHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAAT 2693
Query: 115 ----YYLKEYLKVVSETNDAIRKALEEFAEM--KEREEKKANLEREEKKRDYQA 162
+Y KV ET ++ + + + + E+K L ++ R QA
Sbjct: 2694 LIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQA 2747
Score = 36.6 bits (83), Expect = 0.036
Identities = 27/126 (21%), Positives = 59/126 (46%), Gaps = 14/126 (11%)
Query: 18 YYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQL 77
Y F V+ ++K + A + +QS +RG Q R H+ V IQ ++R+++ +K++
Sbjct: 1619 YIFAMKVLASYQKTRS-AVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEF-- 1675
Query: 78 TVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALEE 137
++L NA +++Q + + RK + +++ + + EE
Sbjct: 1676 ----------LSLKNA-TIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREE 1724
Query: 138 FAEMKE 143
+ +M+E
Sbjct: 1725 YMQMRE 1730
Score = 35.4 bits (80), Expect = 0.080
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 54/166 (32%)
Query: 31 KENDAAVKIQSWFRG-CQVRAYIRHL-----------------NRIVTIIQKWWRSFLGR 72
K+ ++ + IQ WFR Q + +I+ NR ++IQK R FL R
Sbjct: 3139 KQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLR 3198
Query: 73 KQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIR 132
K+ + + + ++IQ WRGY RK ND +
Sbjct: 3199 KKQEK-------------FTSGIIKIQALWRGYSWRK-----------------KNDCTK 3228
Query: 133 -KALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGI 177
KA+ ++ RE + E K A +HYLL+ K + I
Sbjct: 3229 IKAIRLSLQVVNRE-----IREENKLYKRTALALHYLLTYKHLSAI 3269
Score = 35.0 bits (79), Expect = 0.10
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 17/119 (14%)
Query: 10 RSSTVGNQYYFRNSVVDPFRK---KENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWW 66
++S V Q Y N R+ ++ +AV +Q+ FRG + R +++ ++ T+IQ +
Sbjct: 2359 QASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRF 2418
Query: 67 RSFLGR--------------KQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYL 111
RS L R ++Y+ T+ + A+ IQ +R V+K L
Sbjct: 2419 RSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKL 2477
Score = 34.7 bits (78), Expect = 0.14
Identities = 28/120 (23%), Positives = 60/120 (50%), Gaps = 17/120 (14%)
Query: 6 RLQARSSTVGNQYYFRNSVVDPFRK--KENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQ 63
+L+ + TV +Y+ F++ K + + IQ+ FRG + R +++ ++ T+IQ
Sbjct: 2211 KLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQ 2270
Query: 64 KWWRS------FLGRKQYQLTVQVAY--------YTMMMNLYNAMAVRIQRRWRGYRVRK 109
+ +R+ FL K+ + +Q Y + + + NA+ ++IQ +R + +RK
Sbjct: 2271 RRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAV-IKIQSSYRRWMIRK 2329
Score = 34.3 bits (77), Expect = 0.18
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 15/91 (16%)
Query: 36 AVKI-QSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGR------KQYQLTVQVAYYTM-- 86
AVK+ Q+ FRG +VR +R + T+IQ +R + + K+ TVQ Y+ M
Sbjct: 2169 AVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKE 2228
Query: 87 ---MMNLYNAM---AVRIQRRWRGYRVRKYL 111
YN + + IQ +RG + R++L
Sbjct: 2229 RNIQFQRYNKLRHSVIYIQAIFRGKKARRHL 2259
Score = 33.9 bits (76), Expect = 0.23
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 14/114 (12%)
Query: 7 LQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWW 66
L+ R S V Q FR K + +A IQS FR VR L + +Q+ +
Sbjct: 2382 LRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKY 2441
Query: 67 RS----------FLGRKQYQLTVQVAYYTMM----MNLYNAMAVRIQRRWRGYR 106
R+ FL ++ +T+Q +Y +M + AV IQ +R YR
Sbjct: 2442 RATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYR 2495
Score = 33.5 bits (75), Expect = 0.30
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 18/94 (19%)
Query: 34 DAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNA 93
+A +KIQS +R +R +R ++R T IQ +R +YQ Q + ++ Y A
Sbjct: 2313 NAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQAS--VVIQQQYQA 2370
Query: 94 ----------------MAVRIQRRWRGYRVRKYL 111
AV +Q +RG + R++L
Sbjct: 2371 NRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHL 2404
Score = 33.1 bits (74), Expect = 0.40
Identities = 30/136 (22%), Positives = 62/136 (45%), Gaps = 26/136 (19%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAM 94
A + +QS ++G +R ++ ++ IIQ ++R + +K++++ +
Sbjct: 1950 AVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKA------------- 1996
Query: 95 AVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALEEFAEMKEREE----KKAN 150
A+ IQ+ +R Y + + N+ YLK T A+ + MK R+ KA
Sbjct: 1997 ALLIQKYYRAYSIGREQ-NHLYLK--------TKAAVVTLQSAYRGMKVRKRIKDCNKAA 2047
Query: 151 LEREEKKRDYQARKMH 166
+ + K R Y+ +K +
Sbjct: 2048 VTIQSKYRAYKTKKKY 2063
Score = 30.4 bits (67), Expect = 2.6
Identities = 41/178 (23%), Positives = 84/178 (47%), Gaps = 28/178 (15%)
Query: 4 LARLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGC-QVRAYIRHLNRIVTII 62
L ++Q +++++ Y+ R S F K + + + +QS R V +Y R+L VTI
Sbjct: 1343 LEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSII-LQSRIRMIIAVTSYKRYLWATVTI- 1400
Query: 63 QKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYL---------FN 113
Q+ WR++L RKQ Q + M+ + + R+W+ +++ + F
Sbjct: 1401 QRHWRAYLRRKQDQQRYE------MLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFR 1454
Query: 114 YYYLKEYLKVVSETNDAIRKALEEFAEMKEREEKKANLER-----EEKKRDYQARKMH 166
++L++ K E N AI ++ + M + K + +++ R +QA+K++
Sbjct: 1455 EWHLRKQAK---EENSAI--IIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLY 1507
Score = 30.4 bits (67), Expect = 2.6
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 9/101 (8%)
Query: 11 SSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFL 70
+S + Q Y+R V +A +K+QS + Q R HL IQ+ +RS
Sbjct: 1657 TSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS-- 1714
Query: 71 GRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYL 111
K+ + Y M +++Q RGY VRK +
Sbjct: 1715 --KKIAAQKREEYMQM-----RESCIKLQAFVRGYLVRKQM 1748
Score = 30.0 bits (66), Expect = 3.4
Identities = 24/104 (23%), Positives = 52/104 (50%), Gaps = 14/104 (13%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAM 94
+AV IQ+ ++G + R +R ++ +IQ +R + +QY ++ + T +
Sbjct: 2533 SAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMY---RQYCFYQKLQWATKI------- 2582
Query: 95 AVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDA-IRKALEE 137
IQ ++R + ++ +F + LK+ V + D I+K ++E
Sbjct: 2583 ---IQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQE 2623
Score = 29.6 bits (65), Expect = 4.4
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 34/166 (20%)
Query: 61 IIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVR-KYLFNYYY--- 116
+IQK+WR L +++ + + + + N A IQ WR Y R ++L YY
Sbjct: 1321 VIQKYWRRVLAQRKLLMLKK----EKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSII 1376
Query: 117 LKEYLKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPG 176
L+ ++++ R +A + + +A L R++ ++ Y+ K L
Sbjct: 1377 LQSRIRMIIAVTSYKRYL---WATVTIQRHWRAYLRRKQDQQRYEMLKSSTL-------- 1425
Query: 177 IYNSPFRKEPDPWELQ-----------LQKAKPLTHRRPKVKQKDS 211
I S FRK W+ + LQ+A H R + K+++S
Sbjct: 1426 IIQSMFRK----WKQRKMQSQVKATVILQRAFREWHLRKQAKEENS 1467
Score = 29.6 bits (65), Expect = 4.4
Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 14/110 (12%)
Query: 8 QARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWR 67
+ ++ST+ Q +R + K AA KIQ+W+R + + + V IIQ +
Sbjct: 2931 EIKNSTIKIQAMWRRYRAKKYLCKVK-AACKIQAWYRCWRAHKEYLAILKAVKIIQGCFY 2989
Query: 68 SFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYL 117
+ L R T +N+ A A+ IQR+WR K ++ +
Sbjct: 2990 TKLER------------TRFLNV-RASAIIIQRKWRAILPAKIAHEHFLM 3026
Score = 28.9 bits (63), Expect = 7.5
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 14/107 (13%)
Query: 17 QYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIV-TIIQKWW----RSFLG 71
Q FR V +K AA IQS +R + + Y L +I T+ Q++W R+
Sbjct: 2174 QASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQF 2233
Query: 72 RKQYQLTVQVAYYTMM---------MNLYNAMAVRIQRRWRGYRVRK 109
++ +L V Y + + + + A IQRR+R +R+
Sbjct: 2234 QRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRR 2280
Score = 28.5 bits (62), Expect = 9.8
Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 20/138 (14%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAM 94
AA++IQ + + R R +Q ++R++ RKQ+ LY
Sbjct: 2839 AALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL-------------LYRKA 2885
Query: 95 AVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALEEFAEMKEREEKKANLERE 154
AV +Q +R + K + + YL++ S ++ + K +E K + ++ +
Sbjct: 2886 AVVLQNHYRAFLSAK-----HQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQ 2940
Query: 155 EKKRDYQARKMHYLLSTK 172
R Y+A+K YL K
Sbjct: 2941 AMWRRYRAKK--YLCKVK 2956
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/182 (24%), Positives = 86/182 (47%), Gaps = 29/182 (15%)
Query: 19 YFRNSVVDPFRKKEND----AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQ 74
+ R S+ K+ + AA+ I++ G R R + V IIQK +R+FL R++
Sbjct: 725 FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRR 784
Query: 75 YQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKA 134
+ ++L A A+ Q++ RG R+ Y ++++E + K
Sbjct: 785 F------------LHLKKA-AIVFQKQLRGQIARRV---------YRQLLAEKREQEEKK 822
Query: 135 LEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNSPFRKEPD-PWELQL 193
+E E K+REE++ ERE ++ + +A++ +++ + S +KE + EL+
Sbjct: 823 KQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS--QKEAELTRELEK 880
Query: 194 QK 195
QK
Sbjct: 881 QK 882
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 25/161 (15%)
Query: 37 VKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQ-LTVQVAYYTMMMNLYNAMA 95
+ +Q WFR R + HL + IIQ++WR++L +KQ + VQ + M + A
Sbjct: 1024 ILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMA-----SAA 1078
Query: 96 VRIQRRWRGYRVR-KYL------------FNYYYLKEYLKVVSETNDAIRKALEEFAEMK 142
+Q WR + R +YL + YY + ++ + A KA E +
Sbjct: 1079 ALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAI--CIQARWKAYRESKRYQ 1136
Query: 143 EREEKKANLERE----EKKRDYQARKMHYLLSTKQIPGIYN 179
E+ +K L+ ++ ++A K L TK G+ N
Sbjct: 1137 EQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVN 1177
Score = 30.4 bits (67), Expect = 2.6
Identities = 31/137 (22%), Positives = 53/137 (38%), Gaps = 22/137 (16%)
Query: 16 NQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQY 75
NQ R++ V AA +Q+ +R R L +IQ+ WR + R+
Sbjct: 1058 NQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRR-- 1115
Query: 76 QLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKAL 135
+ A+ IQ RW+ YR K Y ++ + ++ T R A
Sbjct: 1116 ----------------HMAAICIQARWKAYRESK---RYQEQRKKIILLQSTCRGFR-AR 1155
Query: 136 EEFAEMKEREEKKANLE 152
+ F +KE+ ++ E
Sbjct: 1156 QRFKALKEQRLRETKPE 1172
>gi|44662817 IQ motif containing F2 [Homo sapiens]
Length = 164
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 7/76 (9%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGR--KQYQLTVQVAYYTMMMNLYN 92
AAVKIQ+W+RG VR + H IIQ WWR L R ++ + +AY T
Sbjct: 46 AAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATR-----E 100
Query: 93 AMAVRIQRRWRGYRVR 108
+++Q R +RVR
Sbjct: 101 RAVIKLQSLVRMWRVR 116
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 42.0 bits (97), Expect = 9e-04
Identities = 44/181 (24%), Positives = 65/181 (35%), Gaps = 40/181 (22%)
Query: 39 IQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRI 98
+QSWFR R + + R IQ WRS+ R+ + T AV +
Sbjct: 963 LQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERT--------------QAAVYL 1008
Query: 99 QRRWRGY--------------RVRKYLFNYYYLKEYLKVVSETNDAIRKALEEFAEMKER 144
Q WRGY R++ + K + +++SE ++ AE KER
Sbjct: 1009 QASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISE---------KQKAEEKER 1059
Query: 145 EEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNSPFRKEPDPWELQLQKAKPLTHRRP 204
E +A E+ QA + P EP E+Q PL H P
Sbjct: 1060 EALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEP---EVQPSDRSPLEHSSP 1116
Query: 205 K 205
+
Sbjct: 1117 E 1117
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 42.0 bits (97), Expect = 9e-04
Identities = 44/181 (24%), Positives = 65/181 (35%), Gaps = 40/181 (22%)
Query: 39 IQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRI 98
+QSWFR R + + R IQ WRS+ R+ + T AV +
Sbjct: 963 LQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERT--------------QAAVYL 1008
Query: 99 QRRWRGY--------------RVRKYLFNYYYLKEYLKVVSETNDAIRKALEEFAEMKER 144
Q WRGY R++ + K + +++SE ++ AE KER
Sbjct: 1009 QASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISE---------KQKAEEKER 1059
Query: 145 EEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNSPFRKEPDPWELQLQKAKPLTHRRP 204
E +A E+ QA + P EP E+Q PL H P
Sbjct: 1060 EALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEP---EVQPSDRSPLEHSSP 1116
Query: 205 K 205
+
Sbjct: 1117 E 1117
>gi|222831628 IQ motif containing F5 [Homo sapiens]
Length = 148
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 22/110 (20%)
Query: 32 ENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGR--------------KQYQL 77
E AAV IQ+W+RG VR + H IIQ WWR L + +Q
Sbjct: 11 ERSAAVFIQAWWRGMLVRRTLLHAALRAWIIQCWWRQVLEKLLAKRRRMVLEFYVQQEWA 70
Query: 78 TVQVAYYTMM-------MNLYNAM-AVRIQRRWRGYRVRKYLFNYYYLKE 119
V++ + M L NA+ +++ RW R ++ +Y LKE
Sbjct: 71 AVRLQSWVRMWCVRQRYCRLLNAVRIIQVYWRWHSCHSRVFIEGHYELKE 120
Score = 32.3 bits (72), Expect = 0.68
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Query: 21 RNSVVDPFRKKENDAAVKIQSWFR-GCQVRAYIRHLNRIVTIIQKWWR 67
R +V F ++ AAV++QSW R C + Y R LN V IIQ +WR
Sbjct: 56 RRRMVLEFYVQQEWAAVRLQSWVRMWCVRQRYCRLLN-AVRIIQVYWR 102
>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
sapiens]
Length = 1551
Score = 40.0 bits (92), Expect = 0.003
Identities = 66/277 (23%), Positives = 109/277 (39%), Gaps = 29/277 (10%)
Query: 47 QVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYR 106
++ A + L+R VT +Q W L T+ A T M Q R
Sbjct: 556 ELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQLRKEVAA 615
Query: 107 VRKYLFNYYYLK-----EYLKVVSETNDAIRKALEEF-AEMKEREEKKANLE--REEKKR 158
+R+ L + + E L + E N + + E AE+ + +E K LE R E +
Sbjct: 616 LREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRETES 675
Query: 159 DYQARK---MHYLLSTKQIPGIYNSPFRKEPDPWE------LQLQKAKPLTHR-RPKVKQ 208
+++A+ + ++ K G + K + E Q A+PL H+ + + Q
Sbjct: 676 NWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARPLDHQWKARRLQ 735
Query: 209 KDSTSLTDWLACTSARSFPRSEILPPINRKQ-CQGPFRDITEVLEQRYRPLEPTLRVAEP 267
K S AR +S + I KQ Q + E Q R L+ + ++
Sbjct: 736 KMEAS---------ARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQA 786
Query: 268 ID-ELKLAREELRREEWLQNVNDNMFLPFSSYHKNEK 303
+ EL + REELR + N +PF S+ +EK
Sbjct: 787 LQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEK 823
>gi|229577354 IQ motif containing F1 [Homo sapiens]
Length = 205
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 32 ENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLG---RKQYQLTVQVAYYTMMM 88
++ A KIQ+W+RG VR + H IIQ WWR L +K+ Q ++
Sbjct: 68 KDTVATKIQAWWRGTLVRRALLHAALSACIIQCWWRLILSKILKKRRQAALEA------F 121
Query: 89 NLYNAMAVRIQRRWRGYRVRK 109
+ AV +Q + R +R+R+
Sbjct: 122 SRKEWAAVTLQSQARMWRIRR 142
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 10/85 (11%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTV-------QVAYYTMM 87
AA+ IQ RG + R R +Q WWR + R+ ++L + +A +
Sbjct: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPL 825
Query: 88 MNLYNAM---AVRIQRRWRGYRVRK 109
Y AM V++Q RGY VR+
Sbjct: 826 ARQYQAMRQRTVQLQALCRGYLVRQ 850
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 38.5 bits (88), Expect = 0.009
Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 23/158 (14%)
Query: 30 KKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQ------LTVQVAY 83
K D + +Q RG + R+ L T+IQ+ WR RK Y L +Q +
Sbjct: 742 KAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALH 801
Query: 84 YTMMMNLYNAMA----VRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALE--- 136
+ ++ +A ++ Q R R Y VRK + L L V + I + L
Sbjct: 802 RSRKLHQQYRLARQRIIQFQARCRAYLVRKAF--RHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 137 --------EFAEMKEREEKKANLEREEKKRDYQARKMH 166
E +M+ EE+K E KK +A + H
Sbjct: 860 RAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKH 897
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 38.5 bits (88), Expect = 0.009
Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 23/158 (14%)
Query: 30 KKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQ------LTVQVAY 83
K D + +Q RG + R+ L T+IQ+ WR RK Y L +Q +
Sbjct: 742 KAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALH 801
Query: 84 YTMMMNLYNAMA----VRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALE--- 136
+ ++ +A ++ Q R R Y VRK + L L V + I + L
Sbjct: 802 RSRKLHQQYRLARQRIIQFQARCRAYLVRKAF--RHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 137 --------EFAEMKEREEKKANLEREEKKRDYQARKMH 166
E +M+ EE+K E KK +A + H
Sbjct: 860 RAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKH 897
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 38.5 bits (88), Expect = 0.009
Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 23/158 (14%)
Query: 30 KKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQ------LTVQVAY 83
K D + +Q RG + R+ L T+IQ+ WR RK Y L +Q +
Sbjct: 742 KAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALH 801
Query: 84 YTMMMNLYNAMA----VRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALE--- 136
+ ++ +A ++ Q R R Y VRK + L L V + I + L
Sbjct: 802 RSRKLHQQYRLARQRIIQFQARCRAYLVRKAF--RHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 137 --------EFAEMKEREEKKANLEREEKKRDYQARKMH 166
E +M+ EE+K E KK +A + H
Sbjct: 860 RAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKH 897
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 38.1 bits (87), Expect = 0.012
Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 29/153 (18%)
Query: 29 RKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMM 88
+++ D A IQ +RG + R + + + +I W+R + +K+YQ T
Sbjct: 701 KQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQT---------- 750
Query: 89 NLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAI---RKALEEFAEMKERE 145
+ A+ IQ RG++ RK L + K + V+ T A +A E +KE
Sbjct: 751 ---KSSALVIQSYIRGWKARKILRELKHQKRCKEAVT-TIAAYWHGTQARRELRRLKEEA 806
Query: 146 EKK------------ANLEREEKKRDYQARKMH 166
K + RE K+ +AR+ H
Sbjct: 807 RNKHAIAVIWAYWLGSKARRELKRLKEEARRKH 839
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 38.1 bits (87), Expect = 0.012
Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 29/153 (18%)
Query: 29 RKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMM 88
+++ D A IQ +RG + R + + + +I W+R + +K+YQ T
Sbjct: 701 KQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQT---------- 750
Query: 89 NLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAI---RKALEEFAEMKERE 145
+ A+ IQ RG++ RK L + K + V+ T A +A E +KE
Sbjct: 751 ---KSSALVIQSYIRGWKARKILRELKHQKRCKEAVT-TIAAYWHGTQARRELRRLKEEA 806
Query: 146 EKK------------ANLEREEKKRDYQARKMH 166
K + RE K+ +AR+ H
Sbjct: 807 RNKHAIAVIWAYWLGSKARRELKRLKEEARRKH 839
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 38.1 bits (87), Expect = 0.012
Identities = 48/209 (22%), Positives = 97/209 (46%), Gaps = 24/209 (11%)
Query: 7 LQARSSTVGNQYYFRNS-----VVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTI 61
L+ R + + Q YFR + KE AA+ IQ RG VR+ + +
Sbjct: 777 LRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATIT 836
Query: 62 IQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYY----- 116
+Q + R FL R++Y+ ++ + +++ Y A A +RR++ +R+++ N
Sbjct: 837 MQAYSRGFLARRRYRKMLE-EHKAVILQKY-ARAWLARRRFQS--IRRFVLNIQLTYRVQ 892
Query: 117 -LKEYLKVVSETNDAIRKALEEFAEMKERE-EKKANLEREEKK-----RDYQARKMHYLL 169
L++ L+ ++ N + + L A ++ + EK LE E +K R+Y+ + Y
Sbjct: 893 RLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRD 952
Query: 170 STKQIPG---IYNSPFRKEPDPWELQLQK 195
+ ++ +NS + + +L+LQ+
Sbjct: 953 AVEEKLAKLQKHNSELETQKEQIQLKLQE 981
>gi|28269672 serologically defined colon cancer antigen 8 [Homo
sapiens]
Length = 713
Score = 37.4 bits (85), Expect = 0.021
Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 121 LKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKR--DYQARKMHYLLSTKQIPGIY 178
L++ + + +R L+E + E+E++KA L REE R + H L T+Q
Sbjct: 486 LEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSI 545
Query: 179 NSPFRKEPDPWELQL-QKAKPLTHRRPKVK-QKDSTSLTDWLACTSARSF 226
F KE LQ Q+ + LT + +++ Q D T +L TS +F
Sbjct: 546 QQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTF 595
>gi|224451032 KIAA1683 isoform a [Homo sapiens]
Length = 1367
Score = 37.0 bits (84), Expect = 0.027
Identities = 21/67 (31%), Positives = 32/67 (47%)
Query: 36 AVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMA 95
A+ IQ+ +RG +VR + HL R T IQ WR + R+ Q+ + + L +
Sbjct: 1140 AMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYSTRRDQARHWQMLHPVTWVELGSRAG 1199
Query: 96 VRIQRRW 102
V R W
Sbjct: 1200 VMSDRSW 1206
Score = 32.0 bits (71), Expect = 0.88
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 13/75 (17%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAM 94
A + IQ+ RG R IR +R +IQ WR + R+ + +L A
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRN------------LAHLCRA- 1162
Query: 95 AVRIQRRWRGYRVRK 109
IQ WRGY R+
Sbjct: 1163 TTTIQSAWRGYSTRR 1177
Score = 29.3 bits (64), Expect = 5.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 31 KENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWR 67
+++ AA IQS +RG ++R +R I+Q WR
Sbjct: 1299 RQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWR 1335
>gi|224451036 KIAA1683 isoform c [Homo sapiens]
Length = 1134
Score = 37.0 bits (84), Expect = 0.027
Identities = 21/67 (31%), Positives = 32/67 (47%)
Query: 36 AVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMA 95
A+ IQ+ +RG +VR + HL R T IQ WR + R+ Q+ + + L +
Sbjct: 907 AMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYSTRRDQARHWQMLHPVTWVELGSRAG 966
Query: 96 VRIQRRW 102
V R W
Sbjct: 967 VMSDRSW 973
Score = 32.0 bits (71), Expect = 0.88
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 13/75 (17%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAM 94
A + IQ+ RG R IR +R +IQ WR + R+ + +L A
Sbjct: 883 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRN------------LAHLCRA- 929
Query: 95 AVRIQRRWRGYRVRK 109
IQ WRGY R+
Sbjct: 930 TTTIQSAWRGYSTRR 944
Score = 29.3 bits (64), Expect = 5.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 31 KENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWR 67
+++ AA IQS +RG ++R +R I+Q WR
Sbjct: 1066 RQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWR 1102
>gi|54606862 KIAA1683 isoform b [Homo sapiens]
Length = 1180
Score = 37.0 bits (84), Expect = 0.027
Identities = 21/67 (31%), Positives = 32/67 (47%)
Query: 36 AVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMA 95
A+ IQ+ +RG +VR + HL R T IQ WR + R+ Q+ + + L +
Sbjct: 953 AMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYSTRRDQARHWQMLHPVTWVELGSRAG 1012
Query: 96 VRIQRRW 102
V R W
Sbjct: 1013 VMSDRSW 1019
Score = 32.0 bits (71), Expect = 0.88
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 13/75 (17%)
Query: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAM 94
A + IQ+ RG R IR +R +IQ WR + R+ + +L A
Sbjct: 929 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRN------------LAHLCRA- 975
Query: 95 AVRIQRRWRGYRVRK 109
IQ WRGY R+
Sbjct: 976 TTTIQSAWRGYSTRR 990
Score = 29.3 bits (64), Expect = 5.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 31 KENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWR 67
+++ AA IQS +RG ++R +R I+Q WR
Sbjct: 1112 RQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWR 1148
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 36.2 bits (82), Expect = 0.047
Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 13/97 (13%)
Query: 29 RKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMM 88
+++ D A IQ +RG + R + + + +I W+R + +K+YQ T
Sbjct: 701 KQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQT---------- 750
Query: 89 NLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVS 125
+ A+ IQ RG++ RK L + K + V+
Sbjct: 751 ---KSSALVIQSYIRGWKARKILRELKHQKRCKEAVT 784
Score = 31.2 bits (69), Expect = 1.5
Identities = 33/127 (25%), Positives = 52/127 (40%), Gaps = 25/127 (19%)
Query: 7 LQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNR------IVT 60
L +S V +Y R + +++ ++ A V IQS+ RG + R +R L VT
Sbjct: 726 LMKKSQIVIAAWYRRYAQQKRYQQTKSSALV-IQSYIRGWKARKILRELKHQKRCKEAVT 784
Query: 61 IIQKWW-------------RSFLGRKQYQLTVQVAYYTMMMNLYNAM--AVRIQRRWRGY 105
I +W R+ G+K Y+ T+Q + + N M I + W
Sbjct: 785 TIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPS- 843
Query: 106 RVRKYLF 112
R YLF
Sbjct: 844 --RPYLF 848
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 35.8 bits (81), Expect = 0.061
Identities = 17/49 (34%), Positives = 23/49 (46%)
Query: 26 DPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQ 74
D + A KIQ+ +RG R + R IQ WWR LGR++
Sbjct: 709 DALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRK 757
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 35.8 bits (81), Expect = 0.061
Identities = 17/49 (34%), Positives = 23/49 (46%)
Query: 26 DPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQ 74
D + A KIQ+ +RG R + R IQ WWR LGR++
Sbjct: 728 DALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRK 776
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 35.8 bits (81), Expect = 0.061
Identities = 17/49 (34%), Positives = 23/49 (46%)
Query: 26 DPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQ 74
D + A KIQ+ +RG R + R IQ WWR LGR++
Sbjct: 693 DALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRK 741
>gi|224591408 SH2 domain containing 4B isoform 2 [Homo sapiens]
Length = 309
Score = 35.4 bits (80), Expect = 0.080
Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 6/96 (6%)
Query: 117 LKEYLKVVSETNDA---IRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQ 173
L E KV E A + + + E + KE EE+K E+ + + +A+++++ L Q
Sbjct: 90 LAEKWKVEMEDRKAAKVLEERIHEEFKRKEEEERKRGEEQIRLQEEQRAKELYWTLKQAQ 149
Query: 174 IPGIYNSPFRKEPDPWELQLQKAKPLTHRRPKVKQK 209
+ + KE WE QL+++K R + Q+
Sbjct: 150 L---HCQASEKEEREWEEQLRRSKAADEERSRRAQR 182
>gi|224591406 SH2 domain containing 4B isoform 1 [Homo sapiens]
Length = 357
Score = 35.4 bits (80), Expect = 0.080
Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 6/96 (6%)
Query: 117 LKEYLKVVSETNDA---IRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQ 173
L E KV E A + + + E + KE EE+K E+ + + +A+++++ L Q
Sbjct: 139 LAEKWKVEMEDRKAAKVLEERIHEEFKRKEEEERKRGEEQIRLQEEQRAKELYWTLKQAQ 198
Query: 174 IPGIYNSPFRKEPDPWELQLQKAKPLTHRRPKVKQK 209
+ + KE WE QL+++K R + Q+
Sbjct: 199 L---HCQASEKEEREWEEQLRRSKAADEERSRRAQR 231
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 35.0 bits (79), Expect = 0.10
Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 16/119 (13%)
Query: 55 LNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNY 114
L +++T Q R FL R +YQ V+ ++ YN A + W ++ Y
Sbjct: 785 LAQLITRTQAMCRGFLARVEYQKMVE-RRESIFCIQYNVRAFMNVKHWPWMKL------Y 837
Query: 115 YYLKEYLKVVSETNDAIRKALEEFAEMKEREEK-KANLEREEKKRDYQARKMHYLLSTK 172
+ +K LK +ET +E A MKE EK K L + E KR KM L+ K
Sbjct: 838 FKIKPLLK-SAETE-------KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEK 888
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,399,457
Number of Sequences: 37866
Number of extensions: 599821
Number of successful extensions: 3867
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 3490
Number of HSP's gapped (non-prelim): 419
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.